Mlab_0731 283ad16faa1a145e7c80ca4152191115 290 Gene3D G3DSA:3.40.50.300 25 272 1.2E-83 T 23-10-2018 Mlab_0731 283ad16faa1a145e7c80ca4152191115 290 ProSitePatterns PS01215 Mrp family signature. 143 159 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 Mlab_0731 283ad16faa1a145e7c80ca4152191115 290 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 35 282 2.0E-98 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 Mlab_0731 283ad16faa1a145e7c80ca4152191115 290 SUPERFAMILY SSF52540 33 262 5.16E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0731 283ad16faa1a145e7c80ca4152191115 290 Hamap MF_02040 Iron-sulfur cluster carrier protein. 25 283 36.595 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein Mlab_0968 d2dc8dd0582f48c15cc0d55a094751bc 235 Pfam PF00535 Glycosyl transferase family 2 3 119 1.7E-28 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Mlab_0968 d2dc8dd0582f48c15cc0d55a094751bc 235 SUPERFAMILY SSF53448 1 214 3.38E-42 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0968 d2dc8dd0582f48c15cc0d55a094751bc 235 Gene3D G3DSA:3.90.550.10 1 199 4.8E-38 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0084 4440b92dfd2fb2d1aca946e7eb08c6a4 240 Gene3D G3DSA:4.10.950.10 163 240 4.3E-36 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0084 4440b92dfd2fb2d1aca946e7eb08c6a4 240 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 239 41.359 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0084 4440b92dfd2fb2d1aca946e7eb08c6a4 240 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 84 1.1E-10 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0084 4440b92dfd2fb2d1aca946e7eb08c6a4 240 SMART SM01382 91 224 3.4E-61 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Mlab_0084 4440b92dfd2fb2d1aca946e7eb08c6a4 240 SUPERFAMILY SSF50249 1 90 2.33E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0084 4440b92dfd2fb2d1aca946e7eb08c6a4 240 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 93 217 1.9E-42 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Mlab_0084 4440b92dfd2fb2d1aca946e7eb08c6a4 240 PIRSF PIRSF002158 1 240 2.8E-62 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0084 4440b92dfd2fb2d1aca946e7eb08c6a4 240 SUPERFAMILY SSF50104 94 238 7.82E-49 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily Mlab_0084 4440b92dfd2fb2d1aca946e7eb08c6a4 240 Gene3D G3DSA:2.40.50.140 1 81 4.2E-19 T 23-10-2018 Mlab_0084 4440b92dfd2fb2d1aca946e7eb08c6a4 240 Gene3D G3DSA:2.30.30.30 85 162 2.6E-26 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 Mlab_0084 4440b92dfd2fb2d1aca946e7eb08c6a4 240 SMART SM01383 11 85 1.4E-16 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0371 fef3ba695d80f62da41af7374a671234 656 Gene3D G3DSA:3.30.70.330 478 552 1.3E-18 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Mlab_0371 fef3ba695d80f62da41af7374a671234 656 Pfam PF00271 Helicase conserved C-terminal domain 230 339 2.9E-32 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0371 fef3ba695d80f62da41af7374a671234 656 Gene3D G3DSA:3.40.50.300 215 440 2.0E-56 T 23-10-2018 Mlab_0371 fef3ba695d80f62da41af7374a671234 656 SMART SM00490 258 339 3.0E-33 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0371 fef3ba695d80f62da41af7374a671234 656 Pfam PF03880 DbpA RNA binding domain 479 549 1.4E-21 T 23-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain Mlab_0371 fef3ba695d80f62da41af7374a671234 656 Pfam PF00270 DEAD/DEAH box helicase 29 193 5.7E-52 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Mlab_0371 fef3ba695d80f62da41af7374a671234 656 SMART SM00487 24 222 1.8E-67 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Mlab_0371 fef3ba695d80f62da41af7374a671234 656 Gene3D G3DSA:3.40.50.300 5 211 1.7E-77 T 23-10-2018 Mlab_0371 fef3ba695d80f62da41af7374a671234 656 SUPERFAMILY SSF52540 72 360 2.0E-78 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0096 74d99eb3b1897b4025de1506dc5546da 130 SUPERFAMILY SSF56047 4 130 8.24E-37 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0096 74d99eb3b1897b4025de1506dc5546da 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0096 74d99eb3b1897b4025de1506dc5546da 130 Pfam PF00410 Ribosomal protein S8 5 130 3.3E-26 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0096 74d99eb3b1897b4025de1506dc5546da 130 Gene3D G3DSA:3.30.1490.10 70 130 2.3E-29 T 23-10-2018 Mlab_0096 74d99eb3b1897b4025de1506dc5546da 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 36.362 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0096 74d99eb3b1897b4025de1506dc5546da 130 Gene3D G3DSA:3.30.1370.30 1 69 1.4E-23 T 23-10-2018 Mlab_0814 206507e21a1b81d6a6585013cbc53f8f 149 PIRSF PIRSF037181 1 147 2.8E-27 T 23-10-2018 IPR014958 DGC Mlab_0814 206507e21a1b81d6a6585013cbc53f8f 149 Pfam PF08859 DGC domain 18 121 1.6E-30 T 23-10-2018 IPR014958 DGC Mlab_0434 d750350ed359af9f7d64714a97bee4f7 286 SUPERFAMILY SSF56112 96 270 3.47E-25 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily Mlab_0434 d750350ed359af9f7d64714a97bee4f7 286 Pfam PF09202 Rio2, N-terminal 8 87 1.8E-20 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 Mlab_0434 d750350ed359af9f7d64714a97bee4f7 286 SMART SM00090 64 285 1.2E-40 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 Mlab_0434 d750350ed359af9f7d64714a97bee4f7 286 Gene3D G3DSA:1.10.10.10 1 91 1.6E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0434 d750350ed359af9f7d64714a97bee4f7 286 Gene3D G3DSA:3.30.200.20 92 187 7.4E-25 T 23-10-2018 Mlab_0434 d750350ed359af9f7d64714a97bee4f7 286 SUPERFAMILY SSF46785 7 86 1.59E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0434 d750350ed359af9f7d64714a97bee4f7 286 Pfam PF01163 RIO1 family 114 277 3.2E-39 T 23-10-2018 Mlab_0434 d750350ed359af9f7d64714a97bee4f7 286 Gene3D G3DSA:1.10.510.10 190 285 7.9E-26 T 23-10-2018 Mlab_1018 062939c02f54daac380456908c4a1fc3 258 Gene3D G3DSA:3.40.50.7700 126 256 2.6E-34 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Mlab_1018 062939c02f54daac380456908c4a1fc3 258 Pfam PF00731 AIR carboxylase 127 253 9.0E-19 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Mlab_1018 062939c02f54daac380456908c4a1fc3 258 SUPERFAMILY SSF52255 125 254 1.11E-28 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Mlab_1018 062939c02f54daac380456908c4a1fc3 258 SMART SM01001 125 256 3.2E-32 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Mlab_1132 83b684294e4b5045511a11087166002e 212 Gene3D G3DSA:3.40.50.360 1 211 2.8E-46 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1132 83b684294e4b5045511a11087166002e 212 Pfam PF03358 NADPH-dependent FMN reductase 1 109 1.3E-27 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Mlab_1132 83b684294e4b5045511a11087166002e 212 SUPERFAMILY SSF52218 1 196 5.59E-40 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0456 dbe7630fcd2bd32dc1cfe32befd0accf 184 Gene3D G3DSA:3.40.1280.10 4 183 6.5E-67 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Mlab_0456 dbe7630fcd2bd32dc1cfe32befd0accf 184 PIRSF PIRSF016123 4 180 8.7E-75 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 Mlab_0456 dbe7630fcd2bd32dc1cfe32befd0accf 184 SUPERFAMILY SSF75217 8 175 7.72E-67 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases Mlab_0456 dbe7630fcd2bd32dc1cfe32befd0accf 184 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 58 174 7.9E-49 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 Mlab_0456 dbe7630fcd2bd32dc1cfe32befd0accf 184 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 57 172 5.0E-32 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 Mlab_0456 dbe7630fcd2bd32dc1cfe32befd0accf 184 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 6 177 41.061 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 536 7.2E-177 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 Pfam PF03483 B3/4 domain 111 236 1.9E-16 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 SUPERFAMILY SSF46955 270 341 5.4E-15 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 Gene3D G3DSA:3.30.930.10 354 536 2.0E-34 T 23-10-2018 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 SUPERFAMILY SSF56037 80 239 6.02E-9 T 23-10-2018 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 534 32.182 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 SUPERFAMILY SSF46955 5 74 1.28E-6 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 SUPERFAMILY SSF55681 334 534 1.14E-36 T 23-10-2018 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 SMART SM00874 268 337 3.2E-20 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 SMART SM00873 93 251 4.9E-24 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 Gene3D G3DSA:3.50.40.10 74 267 1.4E-62 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 Pfam PF03484 tRNA synthetase B5 domain 272 337 4.8E-15 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 Gene3D G3DSA:3.30.56.10 268 337 5.7E-22 T 23-10-2018 Mlab_1371 05d86170938afe0648f97a6fa235bdfb 540 Gene3D G3DSA:3.30.56.10 1 73 2.4E-13 T 23-10-2018 Mlab_1554 76273a23db520ddaa1fb9b17452cf9ac 246 Hamap MF_01093 Tetrahydromethanopterin S-methyltransferase subunit A [mtrA]. 1 184 40.426 T 23-10-2018 IPR005778 Tetrahydromethanopterin S-methyltransferase subunit A, MtrA GO:0006814|GO:0030269|GO:0050897 KEGG: 00680+2.1.1.86 Mlab_1554 76273a23db520ddaa1fb9b17452cf9ac 246 Pfam PF04210 Tetrahydromethanopterin S-methyltransferase, subunit G 183 237 6.3E-23 T 23-10-2018 IPR005866 Tetrahydromethanopterin S-methyltransferase, subunit G GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1554 76273a23db520ddaa1fb9b17452cf9ac 246 TIGRFAM TIGR01111 mtrA: tetrahydromethanopterin S-methyltransferase, subunit A 1 234 9.5E-88 T 23-10-2018 IPR005778 Tetrahydromethanopterin S-methyltransferase subunit A, MtrA GO:0006814|GO:0030269|GO:0050897 KEGG: 00680+2.1.1.86 Mlab_1554 76273a23db520ddaa1fb9b17452cf9ac 246 TIGRFAM TIGR01149 mtrG: tetrahydromethanopterin S-methyltransferase, subunit G 185 239 1.8E-21 T 23-10-2018 IPR005866 Tetrahydromethanopterin S-methyltransferase, subunit G GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1554 76273a23db520ddaa1fb9b17452cf9ac 246 PIRSF PIRSF500207 1 238 9.5E-86 T 23-10-2018 IPR005778 Tetrahydromethanopterin S-methyltransferase subunit A, MtrA GO:0006814|GO:0030269|GO:0050897 KEGG: 00680+2.1.1.86 Mlab_1554 76273a23db520ddaa1fb9b17452cf9ac 246 ProDom PD012265 METHYLTRANSFERASE SUBUNIT G M TETRAHYDROMETHANOPTERIN TRANSFERASE MEMBRANE S-METHYLTRANSFERASE N5-METHYLTETRAHYDROMETHANOPTERIN--COENZYME METHANOGENESIS 186 236 3.0E-14 T 23-10-2018 IPR005866 Tetrahydromethanopterin S-methyltransferase, subunit G GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1554 76273a23db520ddaa1fb9b17452cf9ac 246 Pfam PF04208 Tetrahydromethanopterin S-methyltransferase, subunit A 4 173 3.2E-84 T 23-10-2018 IPR030688 Methyltransferase MtrA/MtxA KEGG: 00680+2.1.1.86 Mlab_1554 76273a23db520ddaa1fb9b17452cf9ac 246 Hamap MF_01500 Tetrahydromethanopterin S-methyltransferase subunit G [mtrG]. 167 246 24.526 T 23-10-2018 IPR005866 Tetrahydromethanopterin S-methyltransferase, subunit G GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1554 76273a23db520ddaa1fb9b17452cf9ac 246 PIRSF PIRSF009452 1 238 4.0E-86 T 23-10-2018 IPR030688 Methyltransferase MtrA/MtxA KEGG: 00680+2.1.1.86 Mlab_0683 8906c286155c404a573b2f451597eae6 355 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 10 343 2.1E-119 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 Mlab_0683 8906c286155c404a573b2f451597eae6 355 PIRSF PIRSF003314 4 355 1.2E-124 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 Mlab_0683 8906c286155c404a573b2f451597eae6 355 SMART SM01240 26 350 0.0049 T 23-10-2018 Mlab_0683 8906c286155c404a573b2f451597eae6 355 SUPERFAMILY SSF51395 28 350 1.14E-73 T 23-10-2018 Mlab_0683 8906c286155c404a573b2f451597eae6 355 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 7 347 40.106 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 Mlab_0683 8906c286155c404a573b2f451597eae6 355 Gene3D G3DSA:3.20.20.70 5 355 2.2E-122 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0683 8906c286155c404a573b2f451597eae6 355 Pfam PF01070 FMN-dependent dehydrogenase 169 339 9.0E-12 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 Mlab_0373 db7a029c3baaeac22ddfb6f1ec057625 157 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 2 145 29.173 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal Mlab_0373 db7a029c3baaeac22ddfb6f1ec057625 157 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 3 144 2.2E-48 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal Mlab_0373 db7a029c3baaeac22ddfb6f1ec057625 157 Gene3D G3DSA:3.30.300.20 75 145 3.7E-23 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta Mlab_0373 db7a029c3baaeac22ddfb6f1ec057625 157 Pfam PF07650 KH domain 16 99 2.0E-13 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0373 db7a029c3baaeac22ddfb6f1ec057625 157 SUPERFAMILY SSF54814 16 74 2.09E-9 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Mlab_0373 db7a029c3baaeac22ddfb6f1ec057625 157 SMART SM00322 33 115 0.0014 T 23-10-2018 IPR004087 K Homology domain GO:0003676 Mlab_0373 db7a029c3baaeac22ddfb6f1ec057625 157 Gene3D G3DSA:3.30.300.20 1 74 7.7E-27 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta Mlab_0373 db7a029c3baaeac22ddfb6f1ec057625 157 SUPERFAMILY SSF54814 76 141 4.9E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Mlab_0003 8233fa8793313cfb379ec4be2a880367 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Mlab_0003 8233fa8793313cfb379ec4be2a880367 387 Gene3D G3DSA:3.90.1150.10 29 379 4.8E-125 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_0003 8233fa8793313cfb379ec4be2a880367 387 Gene3D G3DSA:3.40.640.10 62 282 4.8E-125 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_0003 8233fa8793313cfb379ec4be2a880367 387 SUPERFAMILY SSF53383 4 384 8.78E-115 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_0003 8233fa8793313cfb379ec4be2a880367 387 Pfam PF00155 Aminotransferase class I and II 31 379 3.8E-66 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Mlab_1278 5ecc0af7dceefc29f2853e481c838309 420 Gene3D G3DSA:3.30.465.10 321 406 2.9E-19 T 23-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Mlab_1278 5ecc0af7dceefc29f2853e481c838309 420 Pfam PF03471 Transporter associated domain 329 405 3.6E-18 T 23-10-2018 IPR005170 Transporter-associated domain Mlab_1278 5ecc0af7dceefc29f2853e481c838309 420 SMART SM01091 327 409 4.1E-22 T 23-10-2018 IPR005170 Transporter-associated domain Mlab_1278 5ecc0af7dceefc29f2853e481c838309 420 Gene3D G3DSA:3.10.580.10 170 320 1.4E-54 T 23-10-2018 Mlab_1278 5ecc0af7dceefc29f2853e481c838309 420 Pfam PF01595 Domain of unknown function DUF21 8 176 3.9E-51 T 23-10-2018 IPR002550 CNNM, transmembrane domain Mlab_1278 5ecc0af7dceefc29f2853e481c838309 420 Pfam PF00571 CBS domain 263 311 5.0E-4 T 23-10-2018 IPR000644 CBS domain Mlab_1278 5ecc0af7dceefc29f2853e481c838309 420 Pfam PF00571 CBS domain 191 247 2.3E-7 T 23-10-2018 IPR000644 CBS domain Mlab_1278 5ecc0af7dceefc29f2853e481c838309 420 SUPERFAMILY SSF54631 178 314 1.02E-33 T 23-10-2018 Mlab_1278 5ecc0af7dceefc29f2853e481c838309 420 SUPERFAMILY SSF56176 325 414 7.63E-20 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Mlab_1278 5ecc0af7dceefc29f2853e481c838309 420 SMART SM00116 263 311 3.3 T 23-10-2018 IPR000644 CBS domain Mlab_1278 5ecc0af7dceefc29f2853e481c838309 420 SMART SM00116 200 249 0.0074 T 23-10-2018 IPR000644 CBS domain Mlab_0839 af44a48a8737741b9ba4094a4a601fad 387 Gene3D G3DSA:3.30.70.2130 78 218 6.7E-125 T 23-10-2018 Mlab_0839 af44a48a8737741b9ba4094a4a601fad 387 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 4 385 1.3E-114 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_0839 af44a48a8737741b9ba4094a4a601fad 387 SUPERFAMILY SSF53649 1 353 1.39E-33 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Mlab_0839 af44a48a8737741b9ba4094a4a601fad 387 Pfam PF01676 Metalloenzyme superfamily 1 385 7.0E-41 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 Mlab_0839 af44a48a8737741b9ba4094a4a601fad 387 Gene3D G3DSA:3.40.720.10 4 381 6.7E-125 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Mlab_0839 af44a48a8737741b9ba4094a4a601fad 387 TIGRFAM TIGR02535 hyp_Hser_kinase: proposed homoserine kinase 1 385 1.1E-146 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_0839 af44a48a8737741b9ba4094a4a601fad 387 PIRSF PIRSF006392 1 387 9.4E-130 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_0839 af44a48a8737741b9ba4094a4a601fad 387 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 37 196 5.9E-55 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_0867 ba16326533b2caa5af8b9e9095187173 429 SMART SM00382 199 342 7.9E-23 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0867 ba16326533b2caa5af8b9e9095187173 429 Gene3D G3DSA:1.10.8.60 341 415 1.1E-21 T 23-10-2018 Mlab_0867 ba16326533b2caa5af8b9e9095187173 429 ProSitePatterns PS00674 AAA-protein family signature. 310 328 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Mlab_0867 ba16326533b2caa5af8b9e9095187173 429 SUPERFAMILY SSF52540 162 414 2.74E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0867 ba16326533b2caa5af8b9e9095187173 429 Gene3D G3DSA:2.40.50.140 49 155 2.1E-15 T 23-10-2018 Mlab_0867 ba16326533b2caa5af8b9e9095187173 429 Gene3D G3DSA:3.40.50.300 156 340 1.3E-64 T 23-10-2018 Mlab_0867 ba16326533b2caa5af8b9e9095187173 429 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 50 415 1.5E-125 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_0867 ba16326533b2caa5af8b9e9095187173 429 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 339 8.7E-43 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_1550 d471c96e7db41f0a86b8298e78638d94 105 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 14 105 2.2E-38 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 Mlab_1550 d471c96e7db41f0a86b8298e78638d94 105 SMART SM00652 24 105 1.4E-34 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 Mlab_1550 d471c96e7db41f0a86b8298e78638d94 105 Pfam PF01176 Translation initiation factor 1A / IF-1 29 90 1.5E-21 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 Mlab_1550 d471c96e7db41f0a86b8298e78638d94 105 Gene3D G3DSA:2.40.50.140 11 105 6.1E-33 T 23-10-2018 Mlab_1550 d471c96e7db41f0a86b8298e78638d94 105 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 37 59 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 Mlab_1550 d471c96e7db41f0a86b8298e78638d94 105 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 11 105 23.902 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 Mlab_1550 d471c96e7db41f0a86b8298e78638d94 105 SUPERFAMILY SSF50249 18 105 1.42E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_1550 d471c96e7db41f0a86b8298e78638d94 105 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 49 105 1.0E-15 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 Mlab_0988 f4144d41f0a26feb2f4b86c26d82418e 262 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 68 1.6E-16 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal Mlab_0988 f4144d41f0a26feb2f4b86c26d82418e 262 Gene3D G3DSA:1.10.10.10 1 99 2.8E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0988 f4144d41f0a26feb2f4b86c26d82418e 262 SUPERFAMILY SSF46785 7 102 7.58E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0752 cd59c05215176c18207cecaa0e688a91 122 PIRSF PIRSF004977 2 121 2.3E-36 T 23-10-2018 IPR012017 Uncharacterised conserved protein UCP004977 Mlab_0752 cd59c05215176c18207cecaa0e688a91 122 Pfam PF09846 Uncharacterized protein conserved in archaea (DUF2073) 15 118 7.7E-42 T 23-10-2018 IPR012017 Uncharacterised conserved protein UCP004977 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 Hamap MF_00347 Polyphosphate kinase [ppk]. 26 687 24.645 T 23-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 Pfam PF13090 Polyphosphate kinase C-terminal domain 338 682 3.2E-133 T 23-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 Gene3D G3DSA:3.30.870.10 508 688 1.4E-58 T 23-10-2018 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 SUPERFAMILY SSF56024 508 681 5.61E-58 T 23-10-2018 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 Gene3D G3DSA:3.30.1840.10 22 322 4.2E-64 T 23-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 Gene3D G3DSA:3.30.870.10 332 507 1.3E-62 T 23-10-2018 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 SUPERFAMILY SSF56024 336 497 4.19E-44 T 23-10-2018 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 SUPERFAMILY SSF143724 131 323 1.88E-25 T 23-10-2018 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 Pfam PF02503 Polyphosphate kinase middle domain 143 330 1.9E-23 T 23-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 Pfam PF13089 Polyphosphate kinase N-terminal domain 29 133 1.2E-31 T 23-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 PIRSF PIRSF015589 7 688 1.4E-206 T 23-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 28 682 7.7E-197 T 23-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Mlab_0581 afc1038940c46b9732fd4c390ea8b5f8 689 SUPERFAMILY SSF140356 26 129 1.83E-29 T 23-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 Mlab_1099 79b31ab1d2610c1784f0e7e7cb169386 277 SUPERFAMILY SSF52540 1 226 1.5E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1099 79b31ab1d2610c1784f0e7e7cb169386 277 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 277 79.666 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 Mlab_1099 79b31ab1d2610c1784f0e7e7cb169386 277 Gene3D G3DSA:3.40.50.300 1 233 4.2E-51 T 23-10-2018 Mlab_1099 79b31ab1d2610c1784f0e7e7cb169386 277 Pfam PF13500 AAA domain 3 224 1.0E-20 T 23-10-2018 Mlab_1736 366a4931ae0e9531c2fd43380da9be5a 234 Pfam PF02525 Flavodoxin-like fold 1 173 5.1E-25 T 23-10-2018 IPR003680 Flavodoxin-like fold Mlab_1736 366a4931ae0e9531c2fd43380da9be5a 234 Gene3D G3DSA:3.40.50.360 1 232 1.5E-49 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1736 366a4931ae0e9531c2fd43380da9be5a 234 SUPERFAMILY SSF52218 1 227 6.45E-33 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1559 bbfc81208e05cb8bc2d68907801caa42 287 ProDom PD013594 METHYLTRANSFERASE SUBUNIT D M TETRAHYDROMETHANOPTERIN MEMBRANE S-METHYLTRANSFERASE N5-METHYLTETRAHYDROMETHANOPTERIN--COENZYME METHANOGENESIS TRANSFERASE 126 280 9.0E-48 T 23-10-2018 IPR005779 Tetrahydromethanopterin S-methyltransferase, subunit D GO:0005737|GO:0006814|GO:0012506|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1559 bbfc81208e05cb8bc2d68907801caa42 287 Hamap MF_01097 Tetrahydromethanopterin S-methyltransferase subunit D [mtrD]. 29 287 118.93 T 23-10-2018 IPR005779 Tetrahydromethanopterin S-methyltransferase, subunit D GO:0005737|GO:0006814|GO:0012506|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1559 bbfc81208e05cb8bc2d68907801caa42 287 TIGRFAM TIGR01112 mtrD: tetrahydromethanopterin S-methyltransferase, subunit D 52 273 1.9E-70 T 23-10-2018 IPR005779 Tetrahydromethanopterin S-methyltransferase, subunit D GO:0005737|GO:0006814|GO:0012506|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1559 bbfc81208e05cb8bc2d68907801caa42 287 Pfam PF04207 Tetrahydromethanopterin S-methyltransferase, subunit D 52 273 1.2E-90 T 23-10-2018 IPR005779 Tetrahydromethanopterin S-methyltransferase, subunit D GO:0005737|GO:0006814|GO:0012506|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1559 bbfc81208e05cb8bc2d68907801caa42 287 PIRSF PIRSF016552 14 41 320.0 T 23-10-2018 IPR005779 Tetrahydromethanopterin S-methyltransferase, subunit D GO:0005737|GO:0006814|GO:0012506|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1559 bbfc81208e05cb8bc2d68907801caa42 287 PIRSF PIRSF016552 47 287 8.7E-75 T 23-10-2018 IPR005779 Tetrahydromethanopterin S-methyltransferase, subunit D GO:0005737|GO:0006814|GO:0012506|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_0539 56221f91568b2b7a269fb0442c60b6fb 342 Hamap MF_01853 Protein pelota homolog [pelA]. 7 342 32.108 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 Mlab_0539 56221f91568b2b7a269fb0442c60b6fb 342 Gene3D G3DSA:2.30.30.870 5 131 6.1E-32 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain Mlab_0539 56221f91568b2b7a269fb0442c60b6fb 342 SMART SM01194 1 128 8.6E-42 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like Mlab_0539 56221f91568b2b7a269fb0442c60b6fb 342 Gene3D G3DSA:3.30.420.60 132 247 1.9E-19 T 23-10-2018 Mlab_0539 56221f91568b2b7a269fb0442c60b6fb 342 SUPERFAMILY SSF53137 131 244 2.42E-21 T 23-10-2018 Mlab_0539 56221f91568b2b7a269fb0442c60b6fb 342 Gene3D G3DSA:3.30.1330.30 250 342 4.0E-24 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like Mlab_0539 56221f91568b2b7a269fb0442c60b6fb 342 SUPERFAMILY SSF159065 10 127 2.35E-32 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain Mlab_0539 56221f91568b2b7a269fb0442c60b6fb 342 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 10 342 4.5E-79 T 23-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 Mlab_0539 56221f91568b2b7a269fb0442c60b6fb 342 SUPERFAMILY SSF55315 247 342 5.89E-23 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like Mlab_0539 56221f91568b2b7a269fb0442c60b6fb 342 Pfam PF03463 eRF1 domain 1 9 126 1.2E-23 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like Mlab_0539 56221f91568b2b7a269fb0442c60b6fb 342 Pfam PF03465 eRF1 domain 3 251 342 5.9E-17 T 23-10-2018 IPR005142 eRF1 domain 3 Mlab_1175 a3e7958834958634bb52ae3fdf9b7386 267 Gene3D G3DSA:3.30.470.80 160 263 1.8E-25 T 23-10-2018 Mlab_1175 a3e7958834958634bb52ae3fdf9b7386 267 SUPERFAMILY SSF56059 95 260 7.39E-35 T 23-10-2018 Mlab_1175 a3e7958834958634bb52ae3fdf9b7386 267 Gene3D G3DSA:3.30.1490.20 104 150 2.7E-5 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Mlab_1175 a3e7958834958634bb52ae3fdf9b7386 267 Pfam PF08443 RimK-like ATP-grasp domain 88 244 9.5E-19 T 23-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 SUPERFAMILY SSF51905 1 302 1.62E-45 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 Gene3D G3DSA:3.50.50.60 1 400 3.5E-61 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 390 410 1.1E-23 T 23-10-2018 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 1.1E-23 T 23-10-2018 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 1.1E-23 T 23-10-2018 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 21 36 1.1E-23 T 23-10-2018 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 117 126 1.1E-23 T 23-10-2018 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 1.1E-23 T 23-10-2018 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 SUPERFAMILY SSF55424 345 413 1.37E-5 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 5.4E-24 T 23-10-2018 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 5.4E-24 T 23-10-2018 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 5.4E-24 T 23-10-2018 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 5.4E-24 T 23-10-2018 Mlab_1355 55aac92487d3baaec71b07c2ed0588ce 425 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 292 5.3E-40 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Mlab_0375 44a31a7445435522bb9a2e6a1f859417 302 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 145 7.2E-25 T 23-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain Mlab_0375 44a31a7445435522bb9a2e6a1f859417 302 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 300 6.7E-70 T 23-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 Mlab_0375 44a31a7445435522bb9a2e6a1f859417 302 Gene3D G3DSA:1.10.1040.10 172 302 1.3E-41 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Mlab_0375 44a31a7445435522bb9a2e6a1f859417 302 SUPERFAMILY SSF48179 172 299 2.75E-33 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Mlab_0375 44a31a7445435522bb9a2e6a1f859417 302 Gene3D G3DSA:3.40.50.720 1 171 1.8E-34 T 23-10-2018 Mlab_0375 44a31a7445435522bb9a2e6a1f859417 302 SUPERFAMILY SSF51735 1 160 5.51E-9 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0375 44a31a7445435522bb9a2e6a1f859417 302 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 172 299 4.4E-36 T 23-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain Mlab_1618 0aeaf978ccede34fafd987f8b5593f23 222 Gene3D G3DSA:3.40.50.620 1 218 2.9E-72 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_1618 0aeaf978ccede34fafd987f8b5593f23 222 SUPERFAMILY SSF52402 1 220 5.51E-60 T 23-10-2018 Mlab_1618 0aeaf978ccede34fafd987f8b5593f23 222 PIRSF PIRSF006293 1 222 1.4E-72 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Mlab_1618 0aeaf978ccede34fafd987f8b5593f23 222 Pfam PF06508 Queuosine biosynthesis protein QueC 3 211 2.4E-70 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Mlab_1618 0aeaf978ccede34fafd987f8b5593f23 222 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 218 49.744 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Mlab_1618 0aeaf978ccede34fafd987f8b5593f23 222 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 205 2.8E-58 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Mlab_1009 0a4cf0854ff9f15461abe9a0cf70655d 560 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 108 118 - T 23-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Mlab_1009 0a4cf0854ff9f15461abe9a0cf70655d 560 Gene3D G3DSA:3.10.410.10 447 536 6.4E-31 T 23-10-2018 Mlab_1009 0a4cf0854ff9f15461abe9a0cf70655d 560 SUPERFAMILY SSF52540 9 558 7.67E-245 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1009 0a4cf0854ff9f15461abe9a0cf70655d 560 Gene3D G3DSA:3.30.1510.10 134 252 7.1E-210 T 23-10-2018 Mlab_1009 0a4cf0854ff9f15461abe9a0cf70655d 560 Pfam PF01268 Formate--tetrahydrofolate ligase 8 560 1.4E-269 T 23-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Mlab_1009 0a4cf0854ff9f15461abe9a0cf70655d 560 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 6 560 48.076 T 23-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Mlab_1009 0a4cf0854ff9f15461abe9a0cf70655d 560 Gene3D G3DSA:3.40.50.300 11 442 7.1E-210 T 23-10-2018 Mlab_1009 0a4cf0854ff9f15461abe9a0cf70655d 560 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 333 344 - T 23-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Mlab_0665 95654a08b82bc6d4e45d1c0bf9ac5ed7 374 Gene3D G3DSA:3.90.550.10 3 225 8.2E-58 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0665 95654a08b82bc6d4e45d1c0bf9ac5ed7 374 Gene3D G3DSA:2.160.10.10 226 374 6.0E-23 T 23-10-2018 Mlab_0665 95654a08b82bc6d4e45d1c0bf9ac5ed7 374 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 331 360 4.7E-4 T 23-10-2018 IPR001451 Hexapeptide repeat Mlab_0665 95654a08b82bc6d4e45d1c0bf9ac5ed7 374 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 240 274 9.8E-8 T 23-10-2018 IPR001451 Hexapeptide repeat Mlab_0665 95654a08b82bc6d4e45d1c0bf9ac5ed7 374 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 279 308 2.1E-4 T 23-10-2018 IPR001451 Hexapeptide repeat Mlab_0665 95654a08b82bc6d4e45d1c0bf9ac5ed7 374 SUPERFAMILY SSF51161 230 374 7.86E-27 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily Mlab_0665 95654a08b82bc6d4e45d1c0bf9ac5ed7 374 SUPERFAMILY SSF53448 4 300 1.19E-60 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0665 95654a08b82bc6d4e45d1c0bf9ac5ed7 374 Pfam PF00483 Nucleotidyl transferase 6 220 2.6E-31 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Mlab_1650 a74feb770745c617903cc6f0ef2989a3 422 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 418 32.769 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Mlab_1650 a74feb770745c617903cc6f0ef2989a3 422 PIRSF PIRSF000505 1 422 5.1E-133 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Mlab_1650 a74feb770745c617903cc6f0ef2989a3 422 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 23-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Mlab_1650 a74feb770745c617903cc6f0ef2989a3 422 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 412 1.3E-109 T 23-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 Mlab_1650 a74feb770745c617903cc6f0ef2989a3 422 ProSitePatterns PS00885 EPSP synthase signature 2. 329 347 - T 23-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Mlab_1650 a74feb770745c617903cc6f0ef2989a3 422 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 13 417 2.1E-131 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Mlab_1650 a74feb770745c617903cc6f0ef2989a3 422 Gene3D G3DSA:3.65.10.10 18 232 1.3E-129 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Mlab_1650 a74feb770745c617903cc6f0ef2989a3 422 Gene3D G3DSA:3.65.10.10 233 412 1.3E-129 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Mlab_1650 a74feb770745c617903cc6f0ef2989a3 422 SUPERFAMILY SSF55205 2 418 2.75E-118 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Mlab_1079 8513cfc6dbf839ec0a92b326d4669d4b 289 Gene3D G3DSA:3.30.420.180 166 289 1.9E-24 T 23-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 Mlab_1079 8513cfc6dbf839ec0a92b326d4669d4b 289 SUPERFAMILY SSF159664 171 289 2.75E-25 T 23-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 Mlab_1079 8513cfc6dbf839ec0a92b326d4669d4b 289 SUPERFAMILY SSF159672 9 180 5.36E-43 T 23-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 Mlab_1079 8513cfc6dbf839ec0a92b326d4669d4b 289 Pfam PF11760 Cobalamin synthesis G N-terminal 33 111 2.2E-28 T 23-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 Mlab_1079 8513cfc6dbf839ec0a92b326d4669d4b 289 Gene3D G3DSA:3.40.50.11220 6 106 1.0E-24 T 23-10-2018 Mlab_1079 8513cfc6dbf839ec0a92b326d4669d4b 289 Pfam PF01890 Cobalamin synthesis G C-terminus 174 287 3.2E-21 T 23-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 Mlab_0050 908b9b6093edaf1f2f1b02479b8e7061 296 SUPERFAMILY SSF52518 11 283 1.01E-73 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_0050 908b9b6093edaf1f2f1b02479b8e7061 296 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 61 199 1.7E-23 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Mlab_0050 908b9b6093edaf1f2f1b02479b8e7061 296 Gene3D G3DSA:3.40.50.970 3 84 5.5E-7 T 23-10-2018 Mlab_0050 908b9b6093edaf1f2f1b02479b8e7061 296 Gene3D G3DSA:3.40.50.970 85 294 1.1E-65 T 23-10-2018 Mlab_1241 29a0a679b1232f6da65ce6b645c3be37 132 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 3 132 32.781 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1241 29a0a679b1232f6da65ce6b645c3be37 132 ProSitePatterns PS00360 Ribosomal protein S9 signature. 67 85 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 Mlab_1241 29a0a679b1232f6da65ce6b645c3be37 132 SUPERFAMILY SSF54211 4 132 3.03E-33 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_1241 29a0a679b1232f6da65ce6b645c3be37 132 Pfam PF00380 Ribosomal protein S9/S16 8 132 4.5E-31 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 Mlab_1241 29a0a679b1232f6da65ce6b645c3be37 132 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 3 132 8.5E-59 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1241 29a0a679b1232f6da65ce6b645c3be37 132 Gene3D G3DSA:3.30.230.10 1 132 7.5E-47 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Mlab_0064 c536904871daf6fc5049d6414d09416b 336 SUPERFAMILY SSF52540 1 332 1.7E-96 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0064 c536904871daf6fc5049d6414d09416b 336 SMART SM00788 3 331 4.0E-133 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Mlab_0064 c536904871daf6fc5049d6414d09416b 336 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Mlab_0064 c536904871daf6fc5049d6414d09416b 336 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 336 87.764 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Mlab_0064 c536904871daf6fc5049d6414d09416b 336 Pfam PF00709 Adenylosuccinate synthetase 4 145 6.5E-35 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Mlab_0064 c536904871daf6fc5049d6414d09416b 336 Pfam PF00709 Adenylosuccinate synthetase 148 287 1.9E-40 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Mlab_0064 c536904871daf6fc5049d6414d09416b 336 Gene3D G3DSA:3.40.440.10 1 336 6.1E-120 T 23-10-2018 Mlab_1097 380569a642eecf2d02911c52c60f8112 243 SMART SM00382 32 228 1.1E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1097 380569a642eecf2d02911c52c60f8112 243 Pfam PF00005 ABC transporter 24 172 1.8E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1097 380569a642eecf2d02911c52c60f8112 243 SUPERFAMILY SSF52540 3 224 6.96E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1097 380569a642eecf2d02911c52c60f8112 243 Gene3D G3DSA:3.40.50.300 1 239 5.3E-60 T 23-10-2018 Mlab_0336 7585b27db817537e7fc54221e114a58a 319 SUPERFAMILY SSF102114 25 234 9.16E-21 T 23-10-2018 Mlab_0336 7585b27db817537e7fc54221e114a58a 319 Gene3D G3DSA:3.20.20.70 17 269 2.0E-19 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0336 7585b27db817537e7fc54221e114a58a 319 Pfam PF04055 Radical SAM superfamily 25 188 9.4E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0336 7585b27db817537e7fc54221e114a58a 319 SUPERFAMILY SSF46785 255 316 9.73E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0336 7585b27db817537e7fc54221e114a58a 319 Pfam PF13394 4Fe-4S single cluster domain 26 117 2.4E-5 T 23-10-2018 Mlab_0192 eabd9078b5c59becc5717aacfe0039af 309 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 304 33.89 T 23-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 Mlab_0192 eabd9078b5c59becc5717aacfe0039af 309 SUPERFAMILY SSF50486 203 309 1.57E-27 T 23-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 Mlab_0192 eabd9078b5c59becc5717aacfe0039af 309 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 301 5.8E-84 T 23-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 Mlab_0192 eabd9078b5c59becc5717aacfe0039af 309 Pfam PF00551 Formyl transferase 22 179 1.7E-35 T 23-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Mlab_0192 eabd9078b5c59becc5717aacfe0039af 309 Gene3D G3DSA:3.40.50.170 1 204 2.0E-73 T 23-10-2018 Mlab_0192 eabd9078b5c59becc5717aacfe0039af 309 Pfam PF02911 Formyl transferase, C-terminal domain 203 301 1.1E-23 T 23-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Mlab_0192 eabd9078b5c59becc5717aacfe0039af 309 SUPERFAMILY SSF53328 1 205 2.75E-62 T 23-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Mlab_0192 eabd9078b5c59becc5717aacfe0039af 309 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 131 154 - T 23-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Mlab_0192 eabd9078b5c59becc5717aacfe0039af 309 Gene3D G3DSA:3.10.25.10 205 309 4.8E-27 T 23-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Mlab_0013 8e90ab28b20df44a09741591ce93cd6b 303 TIGRFAM TIGR03294 FrhG: coenzyme F420 hydrogenase, subunit gamma 53 283 1.0E-110 T 23-10-2018 IPR017681 Coenzyme F420 hydrogenase, subunit gamma GO:0016151|GO:0050454|GO:0050660|GO:0051536|GO:0055114 KEGG: 00680+1.12.98.1|MetaCyc: PWY-5207 Mlab_0013 8e90ab28b20df44a09741591ce93cd6b 303 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 267 278 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0013 8e90ab28b20df44a09741591ce93cd6b 303 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 64 190 2.0E-23 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0013 8e90ab28b20df44a09741591ce93cd6b 303 SUPERFAMILY SSF56770 53 282 7.06E-37 T 23-10-2018 Mlab_0013 8e90ab28b20df44a09741591ce93cd6b 303 Gene3D G3DSA:3.30.70.20 222 288 4.2E-20 T 23-10-2018 Mlab_0013 8e90ab28b20df44a09741591ce93cd6b 303 Pfam PF13187 4Fe-4S dicluster domain 238 280 1.0E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0013 8e90ab28b20df44a09741591ce93cd6b 303 Gene3D G3DSA:3.40.50.700 52 219 3.1E-46 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily Mlab_0560 3f46a331838c44db9d2e779b6fab32a2 274 Gene3D G3DSA:3.10.310.10 132 261 1.8E-82 T 23-10-2018 Mlab_0560 3f46a331838c44db9d2e779b6fab32a2 274 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 13 274 33.377 T 23-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Mlab_0560 3f46a331838c44db9d2e779b6fab32a2 274 SUPERFAMILY SSF54506 150 272 1.21E-36 T 23-10-2018 Mlab_0560 3f46a331838c44db9d2e779b6fab32a2 274 Pfam PF01678 Diaminopimelate epimerase 15 139 6.1E-33 T 23-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Mlab_0560 3f46a331838c44db9d2e779b6fab32a2 274 Pfam PF01678 Diaminopimelate epimerase 153 265 4.2E-22 T 23-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Mlab_0560 3f46a331838c44db9d2e779b6fab32a2 274 Gene3D G3DSA:3.10.310.10 15 270 1.8E-82 T 23-10-2018 Mlab_0560 3f46a331838c44db9d2e779b6fab32a2 274 SUPERFAMILY SSF54506 13 140 1.02E-36 T 23-10-2018 Mlab_0560 3f46a331838c44db9d2e779b6fab32a2 274 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 13 272 2.1E-76 T 23-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Mlab_1277 f7807b1c31f021d7dfdbb42819d3508d 273 SUPERFAMILY SSF53335 27 262 3.29E-51 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1277 f7807b1c31f021d7dfdbb42819d3508d 273 Pfam PF05050 Methyltransferase FkbM domain 105 242 9.1E-18 T 23-10-2018 IPR006342 Methyltransferase FkbM Mlab_1277 f7807b1c31f021d7dfdbb42819d3508d 273 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 102 235 6.4E-26 T 23-10-2018 IPR006342 Methyltransferase FkbM Mlab_1277 f7807b1c31f021d7dfdbb42819d3508d 273 Gene3D G3DSA:3.40.50.150 90 271 1.7E-41 T 23-10-2018 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 Gene3D G3DSA:3.30.1490.20 122 189 1.0E-9 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 294 1.6E-57 T 23-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 Gene3D G3DSA:3.40.50.20 2 95 2.7E-25 T 23-10-2018 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 SUPERFAMILY SSF52440 1 103 1.58E-26 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 SMART SM01210 328 417 1.1E-20 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 SMART SM01209 103 294 3.3E-89 T 23-10-2018 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 SUPERFAMILY SSF51246 327 417 1.26E-14 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 417 34.888 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 Gene3D G3DSA:3.90.600.10 329 418 3.4E-11 T 23-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 Gene3D G3DSA:3.30.470.20 190 328 1.3E-51 T 23-10-2018 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 SUPERFAMILY SSF56059 104 317 3.72E-44 T 23-10-2018 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 288 295 - T 23-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 417 3.7E-133 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 5.9E-26 T 23-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Mlab_0316 d0bf377f443df1e08d346068ac98b98e 430 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 414 1.6E-12 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Mlab_0458 a39daecb303222c868a658d27922b3fe 211 SMART SM00531 66 199 7.4E-22 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 Mlab_0458 a39daecb303222c868a658d27922b3fe 211 SUPERFAMILY SSF46785 74 129 3.18E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0458 a39daecb303222c868a658d27922b3fe 211 Gene3D G3DSA:2.20.28.30 153 187 2.8E-5 T 23-10-2018 Mlab_0458 a39daecb303222c868a658d27922b3fe 211 Pfam PF08271 TFIIB zinc-binding 157 185 9.3E-8 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type Mlab_0458 a39daecb303222c868a658d27922b3fe 211 Hamap MF_01909 Transcription factor E [tfe]. 8 209 25.631 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 Mlab_0458 a39daecb303222c868a658d27922b3fe 211 Gene3D G3DSA:1.10.10.10 59 130 1.8E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0458 a39daecb303222c868a658d27922b3fe 211 Pfam PF02002 TFIIE alpha subunit 73 150 2.1E-16 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 Mlab_0458 a39daecb303222c868a658d27922b3fe 211 PIRSF PIRSF006373 4 59 46.0 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 Mlab_0458 a39daecb303222c868a658d27922b3fe 211 PIRSF PIRSF006373 42 211 4.2E-45 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 Mlab_0903 10f7f18ac4126e735ed19ccffd666250 291 Pfam PF00535 Glycosyl transferase family 2 1 110 1.2E-22 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Mlab_0903 10f7f18ac4126e735ed19ccffd666250 291 SUPERFAMILY SSF53448 1 218 4.42E-29 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0903 10f7f18ac4126e735ed19ccffd666250 291 Gene3D G3DSA:3.90.550.10 1 224 1.9E-38 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0307 440425de17abb4f9c145318ade719227 124 Gene3D G3DSA:3.10.180.10 2 121 1.4E-23 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Mlab_0307 440425de17abb4f9c145318ade719227 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 118 1.2E-12 T 23-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Mlab_0307 440425de17abb4f9c145318ade719227 124 SUPERFAMILY SSF54593 4 119 4.03E-24 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Mlab_0573 cc77b2e70118dfc4e8ce8eb887584c16 198 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 122 133 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0573 cc77b2e70118dfc4e8ce8eb887584c16 198 Pfam PF12800 4Fe-4S binding domain 43 55 0.49 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0573 cc77b2e70118dfc4e8ce8eb887584c16 198 Pfam PF00037 4Fe-4S binding domain 167 185 1.8E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0573 cc77b2e70118dfc4e8ce8eb887584c16 198 Gene3D G3DSA:3.30.70.20 37 99 2.0E-9 T 23-10-2018 Mlab_0573 cc77b2e70118dfc4e8ce8eb887584c16 198 Gene3D G3DSA:3.30.70.20 100 142 3.5E-6 T 23-10-2018 Mlab_0573 cc77b2e70118dfc4e8ce8eb887584c16 198 Pfam PF12838 4Fe-4S dicluster domain 77 135 3.5E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0573 cc77b2e70118dfc4e8ce8eb887584c16 198 SUPERFAMILY SSF54862 110 192 1.72E-16 T 23-10-2018 Mlab_0573 cc77b2e70118dfc4e8ce8eb887584c16 198 SUPERFAMILY SSF54862 37 97 3.14E-11 T 23-10-2018 Mlab_0573 cc77b2e70118dfc4e8ce8eb887584c16 198 Gene3D G3DSA:3.30.70.20 148 188 2.1E-6 T 23-10-2018 Mlab_0573 cc77b2e70118dfc4e8ce8eb887584c16 198 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 170 181 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 Pfam PF14520 Helix-hairpin-helix domain 895 926 0.0028 T 23-10-2018 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 Gene3D G3DSA:1.10.290.10 273 398 8.2E-106 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 Hamap MF_00952 DNA topoisomerase 1 [topA]. 1 662 40.357 T 23-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 SMART SM00493 1 126 5.8E-16 T 23-10-2018 IPR006171 TOPRIM domain Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 301 315 - T 23-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 Pfam PF01131 DNA topoisomerase 153 554 3.5E-109 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 SUPERFAMILY SSF47794 671 728 3.77E-5 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 Pfam PF01751 Toprim domain 3 138 4.2E-14 T 23-10-2018 IPR006171 TOPRIM domain Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 191 209 1.1E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 482 496 1.1E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 1.1E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 306 315 1.1E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 384 400 1.1E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 Gene3D G3DSA:1.10.460.10 160 565 8.2E-106 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 SMART SM00436 129 221 3.1E-36 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 SUPERFAMILY SSF56712 1 601 1.15E-140 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 Gene3D G3DSA:3.40.50.140 1 151 6.0E-32 T 23-10-2018 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 591 625 1.4E-8 T 23-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 SMART SM00437 265 517 9.1E-64 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 Mlab_1139 2e87940b3f041a66b02bc2a33dba81a6 935 Gene3D G3DSA:2.70.20.10 215 466 8.2E-106 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 Mlab_0787 b5099593e5a340e262af47f5ef0cf80b 320 Gene3D G3DSA:1.10.443.10 142 315 1.0E-46 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Mlab_0787 b5099593e5a340e262af47f5ef0cf80b 320 Pfam PF00589 Phage integrase family 149 301 1.9E-33 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Mlab_0787 b5099593e5a340e262af47f5ef0cf80b 320 SUPERFAMILY SSF56349 23 310 4.41E-53 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Mlab_0787 b5099593e5a340e262af47f5ef0cf80b 320 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 30 130 6.0E-7 T 23-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Mlab_0787 b5099593e5a340e262af47f5ef0cf80b 320 Gene3D G3DSA:1.10.150.130 26 138 3.6E-12 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 SUPERFAMILY SSF52540 178 438 2.43E-83 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 212 433 2.9E-92 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 SUPERFAMILY SSF50615 6 72 2.12E-7 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 87 202 5.6E-42 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 Gene3D G3DSA:1.10.1140.10 434 581 3.1E-47 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 424 433 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 Gene3D G3DSA:3.40.50.300 76 433 1.0E-176 T 23-10-2018 Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 12 71 7.3E-11 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 SUPERFAMILY SSF47917 446 552 3.4E-25 T 23-10-2018 Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 5 579 51.09 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 Gene3D G3DSA:2.40.30.20 2 74 3.8E-24 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Mlab_1222 f42c24c8dd09aa6c2814e776fd3df8f3 581 Gene3D G3DSA:2.40.50.100 118 185 1.0E-176 T 23-10-2018 Mlab_1691 6ce3528550290b618d1e6c483c6d649a 184 Pfam PF00583 Acetyltransferase (GNAT) family 34 130 1.3E-8 T 23-10-2018 IPR000182 GNAT domain Mlab_1691 6ce3528550290b618d1e6c483c6d649a 184 SUPERFAMILY SSF55729 5 162 8.31E-21 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_1691 6ce3528550290b618d1e6c483c6d649a 184 Gene3D G3DSA:3.40.630.30 1 181 3.8E-33 T 23-10-2018 Mlab_1063 03fc3d7e27e7d845a83daa13938b0104 526 Pfam PF00474 Sodium:solute symporter family 38 453 2.0E-47 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Mlab_1063 03fc3d7e27e7d845a83daa13938b0104 526 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 158 183 - T 23-10-2018 IPR018212 Sodium/solute symporter, conserved site Mlab_1063 03fc3d7e27e7d845a83daa13938b0104 526 Gene3D G3DSA:1.20.1730.10 26 518 4.0E-63 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily Mlab_1479 4a88ef843313dd812f8063a2fa0abf7a 87 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 3 85 20.087 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1479 4a88ef843313dd812f8063a2fa0abf7a 87 Gene3D G3DSA:3.10.440.10 2 86 3.5E-31 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1479 4a88ef843313dd812f8063a2fa0abf7a 87 SUPERFAMILY SSF54575 7 84 5.75E-24 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1479 4a88ef843313dd812f8063a2fa0abf7a 87 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 6 54 6.0E-12 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1479 4a88ef843313dd812f8063a2fa0abf7a 87 ProSitePatterns PS01144 Ribosomal protein L31e signature. 46 60 - T 23-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1479 4a88ef843313dd812f8063a2fa0abf7a 87 SMART SM01380 7 81 9.0E-32 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1479 4a88ef843313dd812f8063a2fa0abf7a 87 Pfam PF01198 Ribosomal protein L31e 10 72 6.7E-14 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 Gene3D G3DSA:3.40.50.300 411 592 1.7E-45 T 23-10-2018 Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 Gene3D G3DSA:3.40.50.300 250 410 4.8E-54 T 23-10-2018 Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 Gene3D G3DSA:3.30.2060.10 154 246 3.5E-27 T 23-10-2018 Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 SMART SM00490 456 542 2.0E-16 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 SUPERFAMILY SSF46600 596 641 6.54E-10 T 23-10-2018 IPR036876 UVR domain superfamily Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 Pfam PF02151 UvrB/uvrC motif 609 641 6.9E-11 T 23-10-2018 IPR001943 UVR domain GO:0005515 Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 Pfam PF12344 Ultra-violet resistance protein B 548 590 4.7E-22 T 23-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 Gene3D G3DSA:4.10.860.10 594 643 4.3E-5 T 23-10-2018 Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 Pfam PF04851 Type III restriction enzyme, res subunit 13 100 7.5E-11 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 SUPERFAMILY SSF52540 3 411 4.97E-121 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 SUPERFAMILY SSF52540 37 572 3.45E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 641 2.1E-292 T 23-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 643 41.017 T 23-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 Gene3D G3DSA:3.40.50.300 1 153 1.1E-68 T 23-10-2018 Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 SMART SM00487 9 421 5.1E-27 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Mlab_0911 6b5f1bfc42bf90d28ff870d303edcdb1 644 Pfam PF00271 Helicase conserved C-terminal domain 440 541 1.4E-14 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0181 11c9f3b5b99a20c20e6a1a0ed22059d8 168 Pfam PF01966 HD domain 39 78 2.5E-5 T 23-10-2018 IPR006674 HD domain Mlab_0181 11c9f3b5b99a20c20e6a1a0ed22059d8 168 SMART SM00471 35 154 0.0096 T 23-10-2018 IPR003607 HD/PDEase domain Mlab_0181 11c9f3b5b99a20c20e6a1a0ed22059d8 168 Gene3D G3DSA:1.10.3210.10 15 160 1.0E-8 T 23-10-2018 Mlab_0181 11c9f3b5b99a20c20e6a1a0ed22059d8 168 SUPERFAMILY SSF109604 25 150 1.05E-17 T 23-10-2018 Mlab_0181 11c9f3b5b99a20c20e6a1a0ed22059d8 168 TIGRFAM TIGR00277 HDIG: HDIG domain 37 74 3.3E-8 T 23-10-2018 IPR006675 HDIG domain Mlab_1246 c75f89920ba234ae0f93588e79b0af6a 181 SMART SM00363 108 170 4.4E-8 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1246 c75f89920ba234ae0f93588e79b0af6a 181 SUPERFAMILY SSF55174 17 151 6.32E-28 T 23-10-2018 Mlab_1246 c75f89920ba234ae0f93588e79b0af6a 181 Gene3D G3DSA:3.10.290.10 107 177 2.2E-19 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Mlab_1246 c75f89920ba234ae0f93588e79b0af6a 181 Pfam PF01479 S4 domain 108 150 4.4E-16 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1246 c75f89920ba234ae0f93588e79b0af6a 181 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 161 32.433 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 Mlab_1246 c75f89920ba234ae0f93588e79b0af6a 181 SMART SM01390 2 107 0.0094 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 Mlab_1246 c75f89920ba234ae0f93588e79b0af6a 181 ProSitePatterns PS00632 Ribosomal protein S4 signature. 106 130 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1246 c75f89920ba234ae0f93588e79b0af6a 181 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 164 6.2E-59 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1085 97fd11432efeafb245e68c498a8d44e4 231 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 1 214 1.3E-85 T 23-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 Mlab_1085 97fd11432efeafb245e68c498a8d44e4 231 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 1 216 28.747 T 23-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 Mlab_1085 97fd11432efeafb245e68c498a8d44e4 231 Gene3D G3DSA:1.10.1760.20 1 210 1.6E-54 T 23-10-2018 Mlab_1085 97fd11432efeafb245e68c498a8d44e4 231 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 211 6.9E-53 T 23-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 Mlab_0093 883e4fa16ac5f9d61ca60eb9114d6d2d 239 Pfam PF00900 Ribosomal family S4e 90 158 7.3E-17 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0093 883e4fa16ac5f9d61ca60eb9114d6d2d 239 Pfam PF08071 RS4NT (NUC023) domain 4 31 5.5E-9 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0093 883e4fa16ac5f9d61ca60eb9114d6d2d 239 Gene3D G3DSA:2.40.50.740 116 161 2.6E-11 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0093 883e4fa16ac5f9d61ca60eb9114d6d2d 239 Gene3D G3DSA:3.10.290.40 1 111 1.0E-30 T 23-10-2018 Mlab_0093 883e4fa16ac5f9d61ca60eb9114d6d2d 239 Gene3D G3DSA:2.30.30.30 173 232 1.6E-19 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 Mlab_0093 883e4fa16ac5f9d61ca60eb9114d6d2d 239 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 82 176 6.0E-18 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0093 883e4fa16ac5f9d61ca60eb9114d6d2d 239 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 2 234 30.172 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 SUPERFAMILY SSF50465 316 419 1.44E-37 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 167 3.6E-14 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 Pfam PF00009 Elongation factor Tu GTP binding domain 5 211 2.1E-55 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 Gene3D G3DSA:3.40.50.300 1 216 3.7E-85 T 23-10-2018 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 Gene3D G3DSA:2.40.30.10 314 420 4.4E-41 T 23-10-2018 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 Gene3D G3DSA:2.40.30.10 219 310 9.0E-40 T 23-10-2018 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 422 60.116 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 SUPERFAMILY SSF50447 222 313 4.86E-30 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 423 6.8E-222 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 SUPERFAMILY SSF52540 5 240 1.06E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 61 76 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 Pfam PF03144 Elongation factor Tu domain 2 239 305 2.0E-16 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 Pfam PF03143 Elongation factor Tu C-terminal domain 313 419 1.4E-35 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 PRINTS PR00315 GTP-binding elongation factor signature 88 98 1.8E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.8E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 PRINTS PR00315 GTP-binding elongation factor signature 141 150 1.8E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 PRINTS PR00315 GTP-binding elongation factor signature 68 76 1.8E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1441 5d3af13ea04202f1a215489cc8707418 425 PRINTS PR00315 GTP-binding elongation factor signature 104 115 1.8E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1590 77852c444ec2d7b1395a5b73f484e90c 321 Pfam PF04055 Radical SAM superfamily 14 181 1.1E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_1590 77852c444ec2d7b1395a5b73f484e90c 321 SUPERFAMILY SSF102114 9 282 1.31E-37 T 23-10-2018 Mlab_1590 77852c444ec2d7b1395a5b73f484e90c 321 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 5 311 7.2E-124 T 23-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 Mlab_1590 77852c444ec2d7b1395a5b73f484e90c 321 Hamap MF_01611 FO synthase subunit 1 [cofG]. 4 315 49.669 T 23-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 Mlab_1590 77852c444ec2d7b1395a5b73f484e90c 321 Gene3D G3DSA:3.20.20.70 4 253 4.8E-40 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1590 77852c444ec2d7b1395a5b73f484e90c 321 SMART SM00729 8 226 1.2E-5 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_0555 4e04a58a8d2c0629df164650965bf944 589 Pfam PF00005 ABC transporter 33 213 3.3E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0555 4e04a58a8d2c0629df164650965bf944 589 SMART SM00382 326 530 1.2E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0555 4e04a58a8d2c0629df164650965bf944 589 SMART SM00382 42 271 9.7E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0555 4e04a58a8d2c0629df164650965bf944 589 Gene3D G3DSA:3.40.50.300 296 586 6.6E-56 T 23-10-2018 Mlab_0555 4e04a58a8d2c0629df164650965bf944 589 TIGRFAM TIGR03269 met_CoM_red_A2: methyl coenzyme M reductase system, component A2 28 544 6.5E-251 T 23-10-2018 IPR017669 Methyl coenzyme M reductase system, component A2 Mlab_0555 4e04a58a8d2c0629df164650965bf944 589 Pfam PF00005 ABC transporter 318 472 1.9E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0555 4e04a58a8d2c0629df164650965bf944 589 SUPERFAMILY SSF52540 30 275 4.83E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0555 4e04a58a8d2c0629df164650965bf944 589 SUPERFAMILY SSF52540 310 536 1.2E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0555 4e04a58a8d2c0629df164650965bf944 589 ProSitePatterns PS00211 ABC transporters family signature. 186 200 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 70 81 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 Gene3D G3DSA:3.30.70.890 150 263 6.2E-72 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 Gene3D G3DSA:3.30.230.10 5 149 6.2E-72 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 Pfam PF00288 GHMP kinases N terminal domain 64 131 8.0E-16 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 PRINTS PR00960 LmbP protein signature 111 130 4.9E-17 T 23-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 PRINTS PR00960 LmbP protein signature 233 252 4.9E-17 T 23-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 PRINTS PR00960 LmbP protein signature 69 90 4.9E-17 T 23-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 53 254 1.6E-54 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 SUPERFAMILY SSF55060 145 286 5.22E-36 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 SUPERFAMILY SSF54211 1 140 4.71E-34 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 Hamap MF_00217 Mevalonate kinase [mvk]. 2 284 48.662 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 Mlab_0681 9bc1c34505b5af18a82426cd9f76cdcf 290 Pfam PF08544 GHMP kinases C terminal 197 267 1.2E-12 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain Mlab_1645 2826871f2249b618e238ebe052b37165 594 SUPERFAMILY SSF52518 7 218 1.45E-55 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_1645 2826871f2249b618e238ebe052b37165 594 Pfam PF00037 4Fe-4S binding domain 569 587 8.2E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_1645 2826871f2249b618e238ebe052b37165 594 Gene3D G3DSA:3.40.50.970 1 184 7.8E-53 T 23-10-2018 Mlab_1645 2826871f2249b618e238ebe052b37165 594 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 378 518 4.4E-28 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Mlab_1645 2826871f2249b618e238ebe052b37165 594 SUPERFAMILY SSF52518 349 561 6.87E-36 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_1645 2826871f2249b618e238ebe052b37165 594 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 7 587 8.3E-245 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 Mlab_1645 2826871f2249b618e238ebe052b37165 594 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 572 583 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_1645 2826871f2249b618e238ebe052b37165 594 Gene3D G3DSA:3.30.70.20 536 590 4.0E-9 T 23-10-2018 Mlab_1645 2826871f2249b618e238ebe052b37165 594 Gene3D G3DSA:3.40.50.970 357 535 2.0E-23 T 23-10-2018 Mlab_1645 2826871f2249b618e238ebe052b37165 594 PIRSF PIRSF006439 1 594 2.9E-218 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 Mlab_1645 2826871f2249b618e238ebe052b37165 594 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 18 186 8.1E-11 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Mlab_1007 ac87e2009e2cea49f09008ab54b2e59d 154 SUPERFAMILY SSF50475 2 152 7.11E-40 T 23-10-2018 Mlab_1007 ac87e2009e2cea49f09008ab54b2e59d 154 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 8 151 1.1E-22 T 23-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related Mlab_1007 ac87e2009e2cea49f09008ab54b2e59d 154 Gene3D G3DSA:2.30.110.10 2 153 2.4E-38 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 SMART SM00881 261 354 6.1E-39 T 23-10-2018 IPR003781 CoA-binding GO:0048037 Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 405 544 8.2E-48 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 Pfam PF13380 CoA binding domain 265 388 4.6E-28 T 23-10-2018 IPR003781 CoA-binding GO:0048037 Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 SUPERFAMILY SSF52210 553 703 2.35E-24 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 Gene3D G3DSA:3.40.50.261 550 707 1.5E-30 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 Gene3D G3DSA:3.30.470.20 29 238 4.3E-70 T 23-10-2018 Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 SUPERFAMILY SSF52210 385 545 4.97E-38 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 Gene3D G3DSA:3.40.50.261 384 545 1.9E-49 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 Gene3D G3DSA:3.30.1490.20 47 124 4.3E-70 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 SUPERFAMILY SSF51735 263 392 3.94E-40 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 Pfam PF13549 ATP-grasp domain 26 240 3.6E-64 T 23-10-2018 Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 Gene3D G3DSA:3.40.50.720 261 383 7.8E-45 T 23-10-2018 Mlab_0863 f256b5817265c21edbcc62389e5158f9 707 SUPERFAMILY SSF56059 28 242 3.72E-39 T 23-10-2018 Mlab_0168 55cca3a8ae657ddebb56278df4d823f2 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 317 3.2E-17 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Mlab_0168 55cca3a8ae657ddebb56278df4d823f2 340 SUPERFAMILY SSF52540 4 252 1.45E-67 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0168 55cca3a8ae657ddebb56278df4d823f2 340 Pfam PF00005 ABC transporter 25 182 3.6E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0168 55cca3a8ae657ddebb56278df4d823f2 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 296 5.2E-11 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Mlab_0168 55cca3a8ae657ddebb56278df4d823f2 340 Gene3D G3DSA:3.40.50.300 1 327 2.5E-91 T 23-10-2018 Mlab_0168 55cca3a8ae657ddebb56278df4d823f2 340 SMART SM00382 33 240 2.1E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1203 21732c8d61364785d2d09cf4cc6c13ac 1065 SUPERFAMILY SSF52540 345 843 1.57E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1203 21732c8d61364785d2d09cf4cc6c13ac 1065 Gene3D G3DSA:3.40.50.300 630 850 1.1E-25 T 23-10-2018 Mlab_1203 21732c8d61364785d2d09cf4cc6c13ac 1065 SUPERFAMILY SSF52540 238 421 8.62E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1203 21732c8d61364785d2d09cf4cc6c13ac 1065 Pfam PF00271 Helicase conserved C-terminal domain 698 819 1.4E-12 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_1203 21732c8d61364785d2d09cf4cc6c13ac 1065 Gene3D G3DSA:3.40.50.10810 244 490 6.6E-23 T 23-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Mlab_1203 21732c8d61364785d2d09cf4cc6c13ac 1065 Pfam PF00176 SNF2 family N-terminal domain 229 411 4.5E-11 T 23-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 Mlab_1203 21732c8d61364785d2d09cf4cc6c13ac 1065 SMART SM00490 719 819 4.6E-10 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_1203 21732c8d61364785d2d09cf4cc6c13ac 1065 SMART SM00487 242 433 2.4E-10 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 325 407 1.4E-30 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 SUPERFAMILY SSF50447 204 317 3.26E-33 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 193 9.1E-12 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 6 409 5.4E-198 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 1 410 57.815 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 Gene3D G3DSA:2.40.30.10 205 319 2.9E-41 T 23-10-2018 Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 SUPERFAMILY SSF52540 9 200 1.32E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 Pfam PF00009 Elongation factor Tu GTP binding domain 9 200 1.6E-29 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.9E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 PRINTS PR00315 GTP-binding elongation factor signature 103 114 1.9E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 PRINTS PR00315 GTP-binding elongation factor signature 87 97 1.9E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 PRINTS PR00315 GTP-binding elongation factor signature 141 150 1.9E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 Gene3D G3DSA:3.40.50.300 5 204 2.1E-58 T 23-10-2018 Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 Gene3D G3DSA:2.40.30.10 320 410 4.1E-30 T 23-10-2018 Mlab_0660 6364a1b5b74cd6e693f42b7847c884aa 411 SUPERFAMILY SSF50465 318 410 1.73E-31 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Mlab_1178 bad92cb8dea25f845d90207372101f23 540 Gene3D G3DSA:3.10.310.20 422 537 5.9E-16 T 23-10-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Mlab_1178 bad92cb8dea25f845d90207372101f23 540 Pfam PF00571 CBS domain 69 123 4.0E-7 T 23-10-2018 IPR000644 CBS domain Mlab_1178 bad92cb8dea25f845d90207372101f23 540 Pfam PF00571 CBS domain 246 297 1.5E-6 T 23-10-2018 IPR000644 CBS domain Mlab_1178 bad92cb8dea25f845d90207372101f23 540 SMART SM00116 252 300 2.1 T 23-10-2018 IPR000644 CBS domain Mlab_1178 bad92cb8dea25f845d90207372101f23 540 SMART SM00116 76 124 0.11 T 23-10-2018 IPR000644 CBS domain Mlab_1178 bad92cb8dea25f845d90207372101f23 540 SUPERFAMILY SSF64182 3 532 7.95E-59 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily Mlab_1178 bad92cb8dea25f845d90207372101f23 540 Gene3D G3DSA:3.10.580.10 44 133 1.0E-8 T 23-10-2018 Mlab_1178 bad92cb8dea25f845d90207372101f23 540 Pfam PF07085 DRTGG domain 142 240 3.6E-17 T 23-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Mlab_1178 bad92cb8dea25f845d90207372101f23 540 Gene3D G3DSA:3.90.1640.10 255 421 4.9E-44 T 23-10-2018 Mlab_1178 bad92cb8dea25f845d90207372101f23 540 SUPERFAMILY SSF54631 68 297 9.98E-24 T 23-10-2018 Mlab_1178 bad92cb8dea25f845d90207372101f23 540 Pfam PF02833 DHHA2 domain 415 532 6.2E-12 T 23-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Mlab_1178 bad92cb8dea25f845d90207372101f23 540 Pfam PF01368 DHH family 4 378 1.6E-28 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Mlab_1178 bad92cb8dea25f845d90207372101f23 540 Gene3D G3DSA:3.40.1390.20 134 241 9.1E-19 T 23-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Mlab_1178 bad92cb8dea25f845d90207372101f23 540 SMART SM01131 413 536 9.9E-27 T 23-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Mlab_1178 bad92cb8dea25f845d90207372101f23 540 SUPERFAMILY SSF75138 137 249 3.01E-12 T 23-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 Pfam PF13361 UvrD-like helicase C-terminal domain 426 599 3.6E-8 T 23-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 Gene3D G3DSA:3.40.50.300 1 166 1.8E-31 T 23-10-2018 Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 SUPERFAMILY SSF52540 3 816 3.87E-106 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 Pfam PF13361 UvrD-like helicase C-terminal domain 717 815 1.9E-13 T 23-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 Gene3D G3DSA:3.40.50.300 714 831 5.5E-16 T 23-10-2018 Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 SUPERFAMILY SSF52980 883 1014 1.45E-12 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 Gene3D G3DSA:3.90.320.10 865 1031 1.4E-7 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 Gene3D G3DSA:3.40.50.300 218 423 3.9E-29 T 23-10-2018 Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 418 3.2E-54 T 23-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 Pfam PF12705 PD-(D/E)XK nuclease superfamily 889 1026 2.8E-12 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 Gene3D G3DSA:3.40.50.300 428 562 8.9E-15 T 23-10-2018 Mlab_1322 20574226e08ff16c82fbbba360e5898c 1057 Gene3D G3DSA:1.10.486.10 563 713 5.5E-19 T 23-10-2018 Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 SUPERFAMILY SSF46565 7 76 1.44E-18 T 23-10-2018 IPR036869 Chaperone J-domain superfamily Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 PRINTS PR00625 DnaJ domain signature 48 68 9.8E-11 T 23-10-2018 IPR001623 DnaJ domain Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 PRINTS PR00625 DnaJ domain signature 9 27 9.8E-11 T 23-10-2018 IPR001623 DnaJ domain Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 PRINTS PR00625 DnaJ domain signature 27 42 9.8E-11 T 23-10-2018 IPR001623 DnaJ domain Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 Pfam PF01556 DnaJ C terminal domain 96 162 2.7E-6 T 23-10-2018 IPR002939 Chaperone DnaJ, C-terminal Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 Gene3D G3DSA:2.60.260.20 173 250 2.0E-9 T 23-10-2018 Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 Gene3D G3DSA:2.60.260.20 96 172 3.2E-8 T 23-10-2018 Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 SMART SM00271 6 68 5.7E-14 T 23-10-2018 IPR001623 DnaJ domain Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 SUPERFAMILY SSF49493 95 169 7.98E-9 T 23-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 Gene3D G3DSA:1.10.287.110 2 81 1.2E-19 T 23-10-2018 IPR036869 Chaperone J-domain superfamily Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 SUPERFAMILY SSF49493 175 243 1.96E-7 T 23-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 Pfam PF00226 DnaJ domain 8 73 1.9E-16 T 23-10-2018 IPR001623 DnaJ domain Mlab_1413 c157aedf396912f0fdb12b94a8f9bbb0 254 Pfam PF01556 DnaJ C terminal domain 104 244 1.8E-12 T 23-10-2018 IPR002939 Chaperone DnaJ, C-terminal Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 Gene3D G3DSA:3.30.420.40 6 298 1.0E-93 T 23-10-2018 Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 Hamap MF_01447 Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein. 4 525 48.631 T 23-10-2018 IPR009220 Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein GO:0004222|GO:0008270 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 Pfam PF00814 Glycoprotease family 31 290 7.8E-83 T 23-10-2018 IPR000905 Gcp-like domain Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 338 525 7.0E-68 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 289 6.7E-84 T 23-10-2018 IPR017861 Kae1/TsaD family Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 ProSitePatterns PS01016 Glycoprotease family signature. 91 111 - T 23-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 Pfam PF01163 RIO1 family 368 472 1.8E-11 T 23-10-2018 Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 Gene3D G3DSA:3.30.200.20 343 408 2.4E-16 T 23-10-2018 Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 Gene3D G3DSA:1.10.510.10 415 525 1.8E-26 T 23-10-2018 Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 1.1E-33 T 23-10-2018 IPR017861 Kae1/TsaD family Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 246 255 1.1E-33 T 23-10-2018 IPR017861 Kae1/TsaD family Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 1.1E-33 T 23-10-2018 IPR017861 Kae1/TsaD family Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 1.1E-33 T 23-10-2018 IPR017861 Kae1/TsaD family Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 92 111 1.1E-33 T 23-10-2018 IPR017861 Kae1/TsaD family Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 71 91 1.1E-33 T 23-10-2018 IPR017861 Kae1/TsaD family Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 Gene3D G3DSA:3.30.420.40 122 276 1.0E-93 T 23-10-2018 Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 SUPERFAMILY SSF56112 363 501 6.15E-21 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 4 323 37.93 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 6 322 2.0E-148 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 SUPERFAMILY SSF53067 5 288 4.17E-32 T 23-10-2018 Mlab_0653 48e567af6c33642e2cbc18a0ad6eb788 525 PIRSF PIRSF036401 4 525 1.2E-211 T 23-10-2018 IPR009220 Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein GO:0004222|GO:0008270 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 Mlab_1332 56f3dc66b4a3145890f01b79eab5c481 245 SUPERFAMILY SSF144010 7 243 4.05E-75 T 23-10-2018 Mlab_1332 56f3dc66b4a3145890f01b79eab5c481 245 Gene3D G3DSA:3.90.1660.10 50 240 4.4E-78 T 23-10-2018 Mlab_1332 56f3dc66b4a3145890f01b79eab5c481 245 Pfam PF01996 F420-0:Gamma-glutamyl ligase 11 219 2.2E-57 T 23-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 Mlab_1332 56f3dc66b4a3145890f01b79eab5c481 245 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 4 240 3.0E-81 T 23-10-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 Mlab_1332 56f3dc66b4a3145890f01b79eab5c481 245 Gene3D G3DSA:3.30.1330.100 7 226 4.4E-78 T 23-10-2018 Mlab_0939 2337361b3f5be7b2fa9ad2a1106619a6 321 SUPERFAMILY SSF50447 148 235 1.6E-19 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Mlab_0939 2337361b3f5be7b2fa9ad2a1106619a6 321 Gene3D G3DSA:3.40.50.300 4 137 1.3E-8 T 23-10-2018 Mlab_0939 2337361b3f5be7b2fa9ad2a1106619a6 321 Gene3D G3DSA:2.40.30.10 148 261 5.6E-22 T 23-10-2018 Mlab_0939 2337361b3f5be7b2fa9ad2a1106619a6 321 Pfam PF03144 Elongation factor Tu domain 2 161 228 1.5E-7 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 SUPERFAMILY SSF52374 7 640 6.08E-138 T 23-10-2018 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 Gene3D G3DSA:1.10.730.10 638 828 1.1E-43 T 23-10-2018 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 Gene3D G3DSA:3.40.50.620 14 620 3.5E-227 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 SUPERFAMILY SSF47323 645 879 3.92E-46 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 SUPERFAMILY SSF50677 196 391 6.8E-44 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1059 12.783 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 8 849 1.3E-284 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 Pfam PF08264 Anticodon-binding domain of tRNA 689 835 2.2E-28 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 633 6.2E-187 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 218 241 5.5E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 390 405 5.5E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 514 527 5.5E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 553 562 5.5E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 5.5E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 Gene3D G3DSA:3.90.740.10 194 396 3.5E-227 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Mlab_0186 fc1e472042eccda65f2784f075b58763 1066 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0467 9f74f3a66402fceff7ff5e2e0428939d 352 SUPERFAMILY SSF52540 5 236 1.61E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0467 9f74f3a66402fceff7ff5e2e0428939d 352 Gene3D G3DSA:3.40.50.300 4 242 6.2E-68 T 23-10-2018 Mlab_0467 9f74f3a66402fceff7ff5e2e0428939d 352 Pfam PF08402 TOBE domain 273 347 4.9E-6 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 Mlab_0467 9f74f3a66402fceff7ff5e2e0428939d 352 Pfam PF00005 ABC transporter 23 165 1.3E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0467 9f74f3a66402fceff7ff5e2e0428939d 352 SUPERFAMILY SSF50331 241 349 1.19E-11 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Mlab_0467 9f74f3a66402fceff7ff5e2e0428939d 352 SMART SM00382 30 231 1.5E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1483 a132287b50d0878234cbdc7cb887c36b 149 SUPERFAMILY SSF46785 2 149 2.54E-55 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1483 a132287b50d0878234cbdc7cb887c36b 149 Pfam PF01090 Ribosomal protein S19e 3 136 1.1E-56 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1483 a132287b50d0878234cbdc7cb887c36b 149 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 147 36.188 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 Mlab_1483 a132287b50d0878234cbdc7cb887c36b 149 SMART SM01413 3 138 8.1E-89 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1483 a132287b50d0878234cbdc7cb887c36b 149 Gene3D G3DSA:1.10.10.2700 1 149 5.2E-61 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1483 a132287b50d0878234cbdc7cb887c36b 149 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 117 6.0E-43 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0321 4c0eecdf312b850acfbfe791289baa65 101 Gene3D G3DSA:3.30.780.10 25 101 1.5E-28 T 23-10-2018 Mlab_0321 4c0eecdf312b850acfbfe791289baa65 101 Pfam PF01253 Translation initiation factor SUI1 25 95 2.1E-22 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 Mlab_0321 4c0eecdf312b850acfbfe791289baa65 101 SUPERFAMILY SSF55159 5 99 6.28E-28 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 Mlab_0321 4c0eecdf312b850acfbfe791289baa65 101 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 5 100 2.1E-34 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 Mlab_0321 4c0eecdf312b850acfbfe791289baa65 101 Hamap MF_00604 Protein translation factor SUI1 homolog. 7 98 28.161 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea Mlab_0321 4c0eecdf312b850acfbfe791289baa65 101 PIRSF PIRSF037511 1 101 6.9E-26 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 Mlab_0235 5fc4ea9b01766208ed17957fe92ba436 336 Gene3D G3DSA:3.40.718.10 3 335 4.0E-115 T 23-10-2018 Mlab_0235 5fc4ea9b01766208ed17957fe92ba436 336 SMART SM01329 4 324 9.4E-146 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Mlab_0235 5fc4ea9b01766208ed17957fe92ba436 336 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 322 1.4E-90 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Mlab_0235 5fc4ea9b01766208ed17957fe92ba436 336 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 221 240 - T 23-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 Mlab_0235 5fc4ea9b01766208ed17957fe92ba436 336 SUPERFAMILY SSF53659 2 326 1.46E-103 T 23-10-2018 Mlab_0139 25d09506fedaef629ce675a36268a24a 481 SUPERFAMILY SSF54292 2 93 1.44E-17 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Mlab_0139 25d09506fedaef629ce675a36268a24a 481 Pfam PF13183 4Fe-4S dicluster domain 127 196 3.1E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0139 25d09506fedaef629ce675a36268a24a 481 Gene3D G3DSA:3.10.20.30 1 93 2.2E-24 T 23-10-2018 IPR012675 Beta-grasp domain superfamily Mlab_0139 25d09506fedaef629ce675a36268a24a 481 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 52 60 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Mlab_0139 25d09506fedaef629ce675a36268a24a 481 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 5 207 8.9E-52 T 23-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Mlab_0139 25d09506fedaef629ce675a36268a24a 481 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 130 141 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0139 25d09506fedaef629ce675a36268a24a 481 Gene3D G3DSA:1.10.1060.10 94 215 4.3E-23 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Mlab_0139 25d09506fedaef629ce675a36268a24a 481 Pfam PF02754 Cysteine-rich domain 373 454 7.4E-17 T 23-10-2018 IPR004017 Cysteine-rich domain Mlab_0139 25d09506fedaef629ce675a36268a24a 481 Pfam PF02754 Cysteine-rich domain 259 342 1.9E-14 T 23-10-2018 IPR004017 Cysteine-rich domain Mlab_0139 25d09506fedaef629ce675a36268a24a 481 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 182 193 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0139 25d09506fedaef629ce675a36268a24a 481 SUPERFAMILY SSF46548 117 214 3.84E-17 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Mlab_0139 25d09506fedaef629ce675a36268a24a 481 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 3 101 1.0E-22 T 23-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Mlab_1242 9169bf20b90fcc301b68f1894a31e479 140 Pfam PF00572 Ribosomal protein L13 11 100 8.9E-5 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Mlab_1242 9169bf20b90fcc301b68f1894a31e479 140 ProSitePatterns PS00783 Ribosomal protein L13 signature. 77 100 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 Mlab_1242 9169bf20b90fcc301b68f1894a31e479 140 PIRSF PIRSF002181 1 140 2.2E-28 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Mlab_1242 9169bf20b90fcc301b68f1894a31e479 140 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 140 4.3E-46 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Mlab_1242 9169bf20b90fcc301b68f1894a31e479 140 SUPERFAMILY SSF52161 2 139 8.76E-35 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 Mlab_1242 9169bf20b90fcc301b68f1894a31e479 140 Gene3D G3DSA:3.90.1180.10 1 140 1.2E-44 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 Mlab_1242 9169bf20b90fcc301b68f1894a31e479 140 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 2 130 16.596 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Mlab_0624 faed6f18d40ccc03f0c0ed45e19da924 390 Pfam PF02824 TGS domain 333 386 4.0E-8 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 Mlab_0624 faed6f18d40ccc03f0c0ed45e19da924 390 SUPERFAMILY SSF52540 2 255 8.38E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0624 faed6f18d40ccc03f0c0ed45e19da924 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 1.9E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0624 faed6f18d40ccc03f0c0ed45e19da924 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 90 108 1.9E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0624 faed6f18d40ccc03f0c0ed45e19da924 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 88 1.9E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0624 faed6f18d40ccc03f0c0ed45e19da924 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 1.9E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0624 faed6f18d40ccc03f0c0ed45e19da924 390 Gene3D G3DSA:3.10.20.30 312 390 1.8E-27 T 23-10-2018 IPR012675 Beta-grasp domain superfamily Mlab_0624 faed6f18d40ccc03f0c0ed45e19da924 390 SUPERFAMILY SSF81271 314 387 3.05E-15 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Mlab_0624 faed6f18d40ccc03f0c0ed45e19da924 390 Pfam PF01926 50S ribosome-binding GTPase 3 115 3.3E-18 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0624 faed6f18d40ccc03f0c0ed45e19da924 390 Gene3D G3DSA:1.10.8.470 126 213 5.7E-16 T 23-10-2018 Mlab_0624 faed6f18d40ccc03f0c0ed45e19da924 390 Pfam PF08438 GTPase of unknown function C-terminal 218 320 1.2E-26 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal Mlab_1477 0665b86680a5512a3ed1147396cdd7be 147 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 14 141 4.1E-24 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 Mlab_1477 0665b86680a5512a3ed1147396cdd7be 147 Pfam PF02996 Prefoldin subunit 24 142 2.0E-22 T 23-10-2018 IPR004127 Prefoldin alpha-like Mlab_1477 0665b86680a5512a3ed1147396cdd7be 147 SUPERFAMILY SSF46579 14 142 3.14E-22 T 23-10-2018 Mlab_1477 0665b86680a5512a3ed1147396cdd7be 147 Gene3D G3DSA:1.10.287.370 12 144 2.1E-31 T 23-10-2018 IPR009053 Prefoldin Mlab_1477 0665b86680a5512a3ed1147396cdd7be 147 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 9 143 13.625 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 Mlab_0508 9a55dde3a1ae3a74d3a730e479958652 182 Pfam PF03729 Short repeat of unknown function (DUF308) 19 88 7.9E-10 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane Mlab_0508 9a55dde3a1ae3a74d3a730e479958652 182 Pfam PF03729 Short repeat of unknown function (DUF308) 75 136 2.7E-6 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane Mlab_0508 9a55dde3a1ae3a74d3a730e479958652 182 Pfam PF03729 Short repeat of unknown function (DUF308) 132 179 4.6E-8 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane Mlab_0857 fe08e29b0a62ed17d1cabc7a0815aebb 81 SMART SM00899 6 80 9.9E-17 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Mlab_0857 fe08e29b0a62ed17d1cabc7a0815aebb 81 SUPERFAMILY SSF50037 8 79 1.04E-16 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal Mlab_0857 fe08e29b0a62ed17d1cabc7a0815aebb 81 Gene3D G3DSA:2.30.30.90 10 81 1.1E-20 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain Mlab_0857 fe08e29b0a62ed17d1cabc7a0815aebb 81 Pfam PF04023 FeoA domain 6 79 2.3E-15 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Mlab_1247 3eb2a9043f9c2055c1b737a968c36d59 150 PIRSF PIRSF002134 3 150 3.4E-39 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1247 3eb2a9043f9c2055c1b737a968c36d59 150 Pfam PF00416 Ribosomal protein S13/S18 12 138 1.9E-37 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1247 3eb2a9043f9c2055c1b737a968c36d59 150 Gene3D G3DSA:4.10.910.10 90 139 1.0E-19 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1247 3eb2a9043f9c2055c1b737a968c36d59 150 ProSitePatterns PS00646 Ribosomal protein S13 signature. 118 131 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1247 3eb2a9043f9c2055c1b737a968c36d59 150 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 6 149 8.0E-57 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1247 3eb2a9043f9c2055c1b737a968c36d59 150 SUPERFAMILY SSF46946 11 144 1.22E-29 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Mlab_1247 3eb2a9043f9c2055c1b737a968c36d59 150 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 10 149 23.468 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1247 3eb2a9043f9c2055c1b737a968c36d59 150 Gene3D G3DSA:1.10.8.50 1 77 4.8E-20 T 23-10-2018 Mlab_0469 6182383ccdb3216fe68f1b1b13aa1ab7 406 Pfam PF13240 zinc-ribbon domain 329 349 9.7E-7 T 23-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 Mlab_0469 6182383ccdb3216fe68f1b1b13aa1ab7 406 Pfam PF12773 Double zinc ribbon 358 403 2.9E-12 T 23-10-2018 IPR025874 Double zinc ribbon Mlab_0469 6182383ccdb3216fe68f1b1b13aa1ab7 406 Pfam PF13421 SPFH domain-Band 7 family 38 246 1.9E-39 T 23-10-2018 IPR033880 SPFH domain, YdjI-like Mlab_0379 bef087baa114f8c8be05cfd285af8566 166 PIRSF PIRSF005590 1 166 5.4E-69 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0379 bef087baa114f8c8be05cfd285af8566 166 Pfam PF00252 Ribosomal protein L16p/L10e 14 163 2.1E-31 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 Mlab_0379 bef087baa114f8c8be05cfd285af8566 166 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0379 bef087baa114f8c8be05cfd285af8566 166 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 166 34.673 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea Mlab_0379 bef087baa114f8c8be05cfd285af8566 166 SUPERFAMILY SSF54686 4 165 2.49E-58 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 Mlab_0379 bef087baa114f8c8be05cfd285af8566 166 Gene3D G3DSA:3.90.1170.10 1 166 3.5E-65 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 Mlab_1546 ff3b2b4a7b5db811446ebf2b5d5b5ea6 229 Pfam PF03692 Putative zinc- or iron-chelating domain 38 133 2.3E-12 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein Mlab_1346 7686d3140933151c247115f3ee50a6bf 458 SUPERFAMILY SSF64153 13 216 6.8E-39 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 Mlab_1346 7686d3140933151c247115f3ee50a6bf 458 Gene3D G3DSA:3.40.1190.20 201 456 8.8E-63 T 23-10-2018 IPR029056 Ribokinase-like Mlab_1346 7686d3140933151c247115f3ee50a6bf 458 Pfam PF01256 Carbohydrate kinase 218 449 1.9E-44 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Mlab_1346 7686d3140933151c247115f3ee50a6bf 458 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 13 176 2.1E-32 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Mlab_1346 7686d3140933151c247115f3ee50a6bf 458 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 195 456 19.173 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Mlab_1346 7686d3140933151c247115f3ee50a6bf 458 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 192 452 2.5E-62 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Mlab_1346 7686d3140933151c247115f3ee50a6bf 458 Gene3D G3DSA:3.40.50.10260 11 178 3.2E-38 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 Mlab_1346 7686d3140933151c247115f3ee50a6bf 458 SUPERFAMILY SSF53613 200 454 8.65E-51 T 23-10-2018 IPR029056 Ribokinase-like Mlab_1346 7686d3140933151c247115f3ee50a6bf 458 Pfam PF03853 YjeF-related protein N-terminus 35 161 6.5E-27 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Mlab_1346 7686d3140933151c247115f3ee50a6bf 458 PIRSF PIRSF017184 11 167 2.6E-28 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 Mlab_1346 7686d3140933151c247115f3ee50a6bf 458 PIRSF PIRSF017184 181 457 3.2E-47 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 Mlab_0541 2f2421e370d37440c76d06be255b1d96 226 SUPERFAMILY SSF54862 3 70 2.19E-15 T 23-10-2018 Mlab_0541 2f2421e370d37440c76d06be255b1d96 226 Pfam PF14697 4Fe-4S dicluster domain 4 65 6.3E-9 T 23-10-2018 Mlab_0541 2f2421e370d37440c76d06be255b1d96 226 Gene3D G3DSA:3.30.70.20 4 123 4.5E-12 T 23-10-2018 Mlab_0541 2f2421e370d37440c76d06be255b1d96 226 PRINTS PR01868 ABC transporter family E signature 45 69 1.2E-8 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 Mlab_0541 2f2421e370d37440c76d06be255b1d96 226 PRINTS PR01868 ABC transporter family E signature 18 33 1.2E-8 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 Mlab_0541 2f2421e370d37440c76d06be255b1d96 226 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 48 59 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0232 c04b76f1748c5657f544160864df27a4 388 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 192 205 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_0232 c04b76f1748c5657f544160864df27a4 388 Gene3D G3DSA:1.10.238.260 269 383 1.4E-26 T 23-10-2018 Mlab_0232 c04b76f1748c5657f544160864df27a4 388 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 13 29 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_0232 c04b76f1748c5657f544160864df27a4 388 Gene3D G3DSA:3.20.20.70 2 268 6.2E-87 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0232 c04b76f1748c5657f544160864df27a4 388 SUPERFAMILY SSF51569 5 279 7.69E-84 T 23-10-2018 Mlab_0232 c04b76f1748c5657f544160864df27a4 388 Pfam PF00682 HMGL-like 6 262 1.0E-75 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Mlab_1240 7f7327b9a0295998d4737baf387743ae 62 Gene3D G3DSA:1.10.10.60 1 62 9.8E-31 T 23-10-2018 Mlab_1240 7f7327b9a0295998d4737baf387743ae 62 PIRSF PIRSF005653 1 62 1.7E-30 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1240 7f7327b9a0295998d4737baf387743ae 62 SUPERFAMILY SSF46924 1 61 2.75E-27 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1240 7f7327b9a0295998d4737baf387743ae 62 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 1 10 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1240 7f7327b9a0295998d4737baf387743ae 62 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 9 48 8.0E-12 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1240 7f7327b9a0295998d4737baf387743ae 62 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 62 22.05 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1240 7f7327b9a0295998d4737baf387743ae 62 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 58 9.0E-30 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_0803 25ccd71d2cab18fea957f351f567a129 422 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 84 97 - T 23-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 Mlab_0803 25ccd71d2cab18fea957f351f567a129 422 Gene3D G3DSA:3.30.70.3160 45 130 1.1E-112 T 23-10-2018 Mlab_0803 25ccd71d2cab18fea957f351f567a129 422 SUPERFAMILY SSF55120 10 415 4.03E-74 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_0803 25ccd71d2cab18fea957f351f567a129 422 Gene3D G3DSA:3.30.2350.20 131 412 1.1E-112 T 23-10-2018 Mlab_0803 25ccd71d2cab18fea957f351f567a129 422 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 13 418 26.535 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_0803 25ccd71d2cab18fea957f351f567a129 422 PIRSF PIRSF037016 334 421 0.005 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_0803 25ccd71d2cab18fea957f351f567a129 422 PIRSF PIRSF037016 25 327 7.1E-52 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_0803 25ccd71d2cab18fea957f351f567a129 422 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 17 416 1.2E-81 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_0803 25ccd71d2cab18fea957f351f567a129 422 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 12 413 1.5E-138 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_0803 25ccd71d2cab18fea957f351f567a129 422 Gene3D G3DSA:1.10.1510.30 175 263 1.1E-112 T 23-10-2018 Mlab_1361 6f0771045e43f413fca56b8bc8e28c71 103 SUPERFAMILY SSF158436 16 101 7.19E-33 T 23-10-2018 Mlab_1361 6f0771045e43f413fca56b8bc8e28c71 103 Pfam PF03685 Uncharacterised protein family (UPF0147) 21 100 4.8E-34 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 Mlab_1361 6f0771045e43f413fca56b8bc8e28c71 103 Gene3D G3DSA:1.20.1440.50 19 101 1.0E-31 T 23-10-2018 IPR023130 Ta0600-like superfamily Mlab_1361 6f0771045e43f413fca56b8bc8e28c71 103 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 27 100 1.0E-22 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 Mlab_1361 6f0771045e43f413fca56b8bc8e28c71 103 Hamap MF_00342 UPF0147 protein . 20 101 29.948 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 Mlab_1335 5a95b73dc4e5e0d2ef340cb46a0e6caa 257 Gene3D G3DSA:3.30.1330.100 18 239 5.9E-72 T 23-10-2018 Mlab_1335 5a95b73dc4e5e0d2ef340cb46a0e6caa 257 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 21 251 3.3E-62 T 23-10-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 Mlab_1335 5a95b73dc4e5e0d2ef340cb46a0e6caa 257 Gene3D G3DSA:3.90.1660.10 61 252 5.9E-72 T 23-10-2018 Mlab_1335 5a95b73dc4e5e0d2ef340cb46a0e6caa 257 Pfam PF01996 F420-0:Gamma-glutamyl ligase 13 231 2.4E-58 T 23-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 Mlab_1335 5a95b73dc4e5e0d2ef340cb46a0e6caa 257 SUPERFAMILY SSF144010 10 253 4.71E-77 T 23-10-2018 Mlab_0601 c486cabf8839c3ed3f7dd375ded44897 431 SUPERFAMILY SSF54862 262 428 1.09E-15 T 23-10-2018 Mlab_0601 c486cabf8839c3ed3f7dd375ded44897 431 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 386 397 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0601 c486cabf8839c3ed3f7dd375ded44897 431 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 410 421 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0601 c486cabf8839c3ed3f7dd375ded44897 431 Pfam PF00037 4Fe-4S binding domain 383 399 1.6E-4 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0601 c486cabf8839c3ed3f7dd375ded44897 431 Pfam PF12801 4Fe-4S binding domain 343 382 0.0014 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0601 c486cabf8839c3ed3f7dd375ded44897 431 Pfam PF12801 4Fe-4S binding domain 251 296 5.6E-13 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0601 c486cabf8839c3ed3f7dd375ded44897 431 Gene3D G3DSA:3.30.70.20 357 406 6.4E-6 T 23-10-2018 Mlab_1344 1ccf267c9f18845626d56bf0bd690f04 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 48 71 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1344 1ccf267c9f18845626d56bf0bd690f04 194 SUPERFAMILY SSF54189 4 192 3.79E-71 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1344 1ccf267c9f18845626d56bf0bd690f04 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 3 193 36.88 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1344 1ccf267c9f18845626d56bf0bd690f04 194 SMART SM01384 4 191 2.4E-103 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1344 1ccf267c9f18845626d56bf0bd690f04 194 Pfam PF00827 Ribosomal L15 4 188 4.7E-77 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1344 1ccf267c9f18845626d56bf0bd690f04 194 Gene3D G3DSA:3.40.1120.10 2 193 5.9E-73 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1142 367159a42fbead49318beee66b6d0222 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 11 99 17.017 T 23-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Mlab_1142 367159a42fbead49318beee66b6d0222 99 Gene3D G3DSA:1.10.20.60 9 98 3.7E-17 T 23-10-2018 Mlab_1142 367159a42fbead49318beee66b6d0222 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 12 99 3.2E-18 T 23-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Mlab_1142 367159a42fbead49318beee66b6d0222 99 SUPERFAMILY SSF141000 11 98 9.15E-20 T 23-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 Mlab_1142 367159a42fbead49318beee66b6d0222 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 29 94 1.6E-12 T 23-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Mlab_1553 e3fcc6974bfbd52462a99761f58ef1f3 339 PIRSF PIRSF004960 1 339 1.2E-94 T 23-10-2018 IPR023467 Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H GO:0006730|GO:0008168 Mlab_1553 e3fcc6974bfbd52462a99761f58ef1f3 339 Pfam PF02007 Tetrahydromethanopterin S-methyltransferase MtrH subunit 6 325 3.5E-94 T 23-10-2018 IPR023467 Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H GO:0006730|GO:0008168 Mlab_1553 e3fcc6974bfbd52462a99761f58ef1f3 339 TIGRFAM TIGR01114 mtrH: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H 1 338 1.4E-103 T 23-10-2018 IPR023467 Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H GO:0006730|GO:0008168 Mlab_1553 e3fcc6974bfbd52462a99761f58ef1f3 339 ProDom PD009948 METHYLTRANSFERASE SUBUNIT H TRANSFERASE M TETRAHYDROMETHANOPTERIN S-METHYLTRANSFERASE N5-METHYLTETRAHYDROMETHANOPTERIN--COENZYME METHANOGENESIS ONE-CARBON 75 335 7.0E-113 T 23-10-2018 IPR023467 Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H GO:0006730|GO:0008168 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 Pfam PF00271 Helicase conserved C-terminal domain 357 466 6.1E-21 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 Gene3D G3DSA:3.40.50.10130 545 686 2.3E-39 T 23-10-2018 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 Pfam PF12826 Helix-hairpin-helix motif 710 755 6.3E-10 T 23-10-2018 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 Gene3D G3DSA:3.40.50.300 213 484 1.1E-87 T 23-10-2018 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 Gene3D G3DSA:1.10.150.20 689 756 2.5E-16 T 23-10-2018 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 Pfam PF00270 DEAD/DEAH box helicase 18 152 1.2E-17 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 SMART SM00278 736 755 0.0066 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 SMART SM00278 704 723 210.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 SMART SM00891 549 629 4.6E-19 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 SUPERFAMILY SSF52980 546 678 1.98E-30 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 Pfam PF02732 ERCC4 domain 552 675 1.5E-23 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 SUPERFAMILY SSF47781 693 759 4.13E-14 T 23-10-2018 IPR010994 RuvA domain 2-like Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 SMART SM00487 12 206 1.0E-26 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 Gene3D G3DSA:3.40.50.300 8 203 1.2E-60 T 23-10-2018 Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 SUPERFAMILY SSF52540 58 485 3.01E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 SMART SM00490 378 467 2.9E-21 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_1157 00abe36cfc87ba94c2b49c770c36c9bb 763 Gene3D G3DSA:1.20.1320.20 216 344 1.1E-87 T 23-10-2018 Mlab_0162 b29a4c265897dd74871e8c0687a4dcea 139 SUPERFAMILY SSF47598 6 53 3.26E-13 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Mlab_0162 b29a4c265897dd74871e8c0687a4dcea 139 SUPERFAMILY SSF55021 57 138 1.19E-25 T 23-10-2018 Mlab_0162 b29a4c265897dd74871e8c0687a4dcea 139 Pfam PF08753 NikR C terminal nickel binding domain 61 136 7.8E-31 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal Mlab_0162 b29a4c265897dd74871e8c0687a4dcea 139 Gene3D G3DSA:3.30.70.1150 57 139 6.4E-28 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal Mlab_0162 b29a4c265897dd74871e8c0687a4dcea 139 Hamap MF_00476 Nickel-responsive regulator [nikR]. 7 138 27.966 T 23-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 Mlab_0162 b29a4c265897dd74871e8c0687a4dcea 139 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 47 4.4E-8 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Mlab_0162 b29a4c265897dd74871e8c0687a4dcea 139 Gene3D G3DSA:1.10.1220.10 14 53 1.3E-18 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Mlab_0529 b7d3a07f90237853a55cde20922b10b6 251 SUPERFAMILY SSF51735 1 251 7.57E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0529 b7d3a07f90237853a55cde20922b10b6 251 Gene3D G3DSA:3.40.50.720 5 249 2.8E-84 T 23-10-2018 Mlab_0529 b7d3a07f90237853a55cde20922b10b6 251 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 140 157 - T 23-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0529 b7d3a07f90237853a55cde20922b10b6 251 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 116 1.6E-26 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0529 b7d3a07f90237853a55cde20922b10b6 251 PIRSF PIRSF000161 1 251 1.6E-76 T 23-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0529 b7d3a07f90237853a55cde20922b10b6 251 Gene3D G3DSA:3.30.360.10 118 219 2.8E-84 T 23-10-2018 Mlab_0529 b7d3a07f90237853a55cde20922b10b6 251 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 250 1.7E-77 T 23-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0529 b7d3a07f90237853a55cde20922b10b6 251 SUPERFAMILY SSF55347 118 221 6.32E-29 T 23-10-2018 Mlab_0529 b7d3a07f90237853a55cde20922b10b6 251 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 250 30.902 T 23-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0529 b7d3a07f90237853a55cde20922b10b6 251 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 119 249 4.8E-43 T 23-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_1089 d6fcbc2e1950f01cb2e9fc9bfa1729c1 355 Gene3D G3DSA:1.10.3470.10 16 355 1.5E-103 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_1089 d6fcbc2e1950f01cb2e9fc9bfa1729c1 355 Pfam PF01032 FecCD transport family 29 351 3.9E-92 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Mlab_1089 d6fcbc2e1950f01cb2e9fc9bfa1729c1 355 SUPERFAMILY SSF81345 13 351 3.53E-83 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_0489 1a78904a4949c3f047cb45be4cd4165a 268 Hamap MF_00840 Diadenylate cyclase [dacZ]. 7 265 32.575 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type Mlab_0489 1a78904a4949c3f047cb45be4cd4165a 268 SUPERFAMILY SSF143597 102 257 7.32E-28 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily Mlab_0489 1a78904a4949c3f047cb45be4cd4165a 268 Gene3D G3DSA:3.40.1700.10 181 268 4.1E-14 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily Mlab_0489 1a78904a4949c3f047cb45be4cd4165a 268 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 130 255 2.0E-19 T 23-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal Mlab_1253 2bbc774ef225a8569e4e4bf5baac2b7c 247 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 191 205 2.2E-8 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 Mlab_1253 2bbc774ef225a8569e4e4bf5baac2b7c 247 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 33 51 2.2E-8 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 Mlab_1253 2bbc774ef225a8569e4e4bf5baac2b7c 247 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 9 28 2.2E-8 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 Mlab_1253 2bbc774ef225a8569e4e4bf5baac2b7c 247 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 230 247 2.2E-8 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 Mlab_1253 2bbc774ef225a8569e4e4bf5baac2b7c 247 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 1 244 22.101 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 Mlab_1253 2bbc774ef225a8569e4e4bf5baac2b7c 247 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 123 242 4.0E-6 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 Mlab_1253 2bbc774ef225a8569e4e4bf5baac2b7c 247 SUPERFAMILY SSF55979 123 245 7.12E-20 T 23-10-2018 Mlab_1253 2bbc774ef225a8569e4e4bf5baac2b7c 247 Gene3D G3DSA:3.70.10.10 1 247 4.6E-67 T 23-10-2018 Mlab_1253 2bbc774ef225a8569e4e4bf5baac2b7c 247 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 2 101 2.8E-12 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 Mlab_1253 2bbc774ef225a8569e4e4bf5baac2b7c 247 SUPERFAMILY SSF55979 1 120 5.65E-25 T 23-10-2018 Mlab_1017 972d18aa140bff9773db5dbce0276fae 427 SMART SM00382 214 349 9.6E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1017 972d18aa140bff9773db5dbce0276fae 427 Gene3D G3DSA:1.10.8.60 349 416 2.0E-11 T 23-10-2018 Mlab_1017 972d18aa140bff9773db5dbce0276fae 427 ProSitePatterns PS00674 AAA-protein family signature. 319 338 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Mlab_1017 972d18aa140bff9773db5dbce0276fae 427 SUPERFAMILY SSF52540 172 411 6.31E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1017 972d18aa140bff9773db5dbce0276fae 427 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 218 346 3.8E-34 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_1017 972d18aa140bff9773db5dbce0276fae 427 Gene3D G3DSA:3.40.50.300 169 348 2.9E-39 T 23-10-2018 Mlab_1675 9600b053440a71ee4e12581d7f588bb5 281 SUPERFAMILY SSF55120 1 225 4.6E-57 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_1675 9600b053440a71ee4e12581d7f588bb5 281 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 225 26.492 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_1675 9600b053440a71ee4e12581d7f588bb5 281 Gene3D G3DSA:3.30.70.580 1 102 5.1E-20 T 23-10-2018 Mlab_1675 9600b053440a71ee4e12581d7f588bb5 281 Pfam PF01416 tRNA pseudouridine synthase 126 223 1.3E-19 T 23-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_1675 9600b053440a71ee4e12581d7f588bb5 281 PIRSF PIRSF001430 1 241 2.7E-56 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_1675 9600b053440a71ee4e12581d7f588bb5 281 Gene3D G3DSA:3.30.70.660 103 224 4.0E-26 T 23-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 Mlab_1675 9600b053440a71ee4e12581d7f588bb5 281 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 218 6.7E-46 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_0965 4279f56bcb03a83156ff674736f9619d 382 Gene3D G3DSA:3.30.70.20 333 380 2.4E-7 T 23-10-2018 Mlab_0965 4279f56bcb03a83156ff674736f9619d 382 Pfam PF04015 Domain of unknown function (DUF362) 40 240 7.0E-45 T 23-10-2018 IPR007160 Domain of unknown function DUF362 Mlab_0965 4279f56bcb03a83156ff674736f9619d 382 Gene3D G3DSA:3.30.70.20 303 332 8.0E-6 T 23-10-2018 Mlab_0965 4279f56bcb03a83156ff674736f9619d 382 SUPERFAMILY SSF54862 312 372 9.77E-16 T 23-10-2018 Mlab_0965 4279f56bcb03a83156ff674736f9619d 382 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 322 333 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0965 4279f56bcb03a83156ff674736f9619d 382 Pfam PF00037 4Fe-4S binding domain 315 337 2.0E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0675 9f33fcb87fec65438e4a80d41d02a6d5 246 Gene3D G3DSA:2.60.40.2020 154 245 1.0E-19 T 23-10-2018 IPR036331 Chagasin-like superfamily Mlab_0675 9f33fcb87fec65438e4a80d41d02a6d5 246 Pfam PF09394 Chagasin family peptidase inhibitor I42 161 243 1.7E-20 T 23-10-2018 IPR018990 Proteinase inhibitor I42, chagasin Mlab_0675 9f33fcb87fec65438e4a80d41d02a6d5 246 Pfam PF09394 Chagasin family peptidase inhibitor I42 51 125 6.8E-16 T 23-10-2018 IPR018990 Proteinase inhibitor I42, chagasin Mlab_0675 9f33fcb87fec65438e4a80d41d02a6d5 246 Gene3D G3DSA:2.60.40.2020 34 135 1.9E-19 T 23-10-2018 IPR036331 Chagasin-like superfamily Mlab_0675 9f33fcb87fec65438e4a80d41d02a6d5 246 SUPERFAMILY SSF141066 46 130 1.44E-22 T 23-10-2018 IPR036331 Chagasin-like superfamily Mlab_0675 9f33fcb87fec65438e4a80d41d02a6d5 246 SUPERFAMILY SSF141066 155 244 9.55E-22 T 23-10-2018 IPR036331 Chagasin-like superfamily Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 SUPERFAMILY SSF52490 33 227 1.83E-57 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 SMART SM00865 226 343 1.2E-36 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 34 193 4.5E-38 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 SMART SM00864 34 224 1.7E-83 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 ProSitePatterns PS01134 FtsZ protein signature 1. 65 99 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 Pfam PF12327 FtsZ family, C-terminal domain 241 335 3.8E-31 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 PRINTS PR00423 Cell division protein FtsZ signature 147 168 2.6E-32 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 PRINTS PR00423 Cell division protein FtsZ signature 119 139 2.6E-32 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 PRINTS PR00423 Cell division protein FtsZ signature 231 252 2.6E-32 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 PRINTS PR00423 Cell division protein FtsZ signature 208 230 2.6E-32 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 Gene3D G3DSA:3.40.50.1440 31 335 2.5E-101 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 28 355 5.1E-124 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 SUPERFAMILY SSF55307 226 340 5.72E-34 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 30 378 32.235 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 Mlab_0743 b6edfc8b1b82d9b3012b064c6d9eaca0 385 ProSitePatterns PS01135 FtsZ protein signature 2. 118 139 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 SUPERFAMILY SSF51735 307 468 5.14E-42 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 Pfam PF01487 Type I 3-dehydroquinase 5 202 1.6E-33 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 SUPERFAMILY SSF53223 205 306 6.91E-26 T 23-10-2018 Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 Gene3D G3DSA:3.40.50.10860 211 456 2.8E-77 T 23-10-2018 Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 Gene3D G3DSA:3.40.50.720 307 446 2.8E-77 T 23-10-2018 Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 Gene3D G3DSA:3.20.20.70 1 205 6.9E-36 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 177 5.1E-5 T 23-10-2018 Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 326 351 5.1E-5 T 23-10-2018 Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 209 469 4.8E-72 T 23-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 212 294 2.4E-22 T 23-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 322 388 1.6E-9 T 23-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 SUPERFAMILY SSF51569 2 200 5.49E-38 T 23-10-2018 Mlab_1652 7a1f707f7f22208e4cdb75c8bea219ac 473 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 207 470 30.994 T 23-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 Gene3D G3DSA:1.25.40.10 106 210 7.1E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 Gene3D G3DSA:1.25.40.10 4 105 3.3E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 SUPERFAMILY SSF48452 10 167 3.67E-19 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 Pfam PF13432 Tetratricopeptide repeat 251 307 0.0044 T 23-10-2018 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 SMART SM00028 279 312 93.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 SMART SM00028 178 211 12.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 SMART SM00028 37 70 0.51 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 SMART SM00028 245 278 9.9 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 SMART SM00028 138 171 390.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 SMART SM00028 212 244 51.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 SMART SM00028 71 104 1.5 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 Pfam PF13181 Tetratricopeptide repeat 211 240 0.034 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 Pfam PF14559 Tetratricopeptide repeat 18 77 6.7E-6 T 23-10-2018 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 SUPERFAMILY SSF48452 178 305 1.82E-18 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 Pfam PF07719 Tetratricopeptide repeat 178 210 4.2E-5 T 23-10-2018 IPR013105 Tetratricopeptide repeat 2 Mlab_1021 c66ca4f7942c104f7dab0c9c1236debb 334 Gene3D G3DSA:1.25.40.10 211 326 4.3E-14 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0666 ae563129f764ad4394e2f48820b65500 399 Pfam PF00483 Nucleotidyl transferase 4 228 1.9E-40 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Mlab_0666 ae563129f764ad4394e2f48820b65500 399 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 301 334 0.0029 T 23-10-2018 IPR001451 Hexapeptide repeat Mlab_0666 ae563129f764ad4394e2f48820b65500 399 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 299 6.9E-9 T 23-10-2018 IPR001451 Hexapeptide repeat Mlab_0666 ae563129f764ad4394e2f48820b65500 399 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 355 390 4.5E-5 T 23-10-2018 IPR001451 Hexapeptide repeat Mlab_0666 ae563129f764ad4394e2f48820b65500 399 SUPERFAMILY SSF53448 1 306 7.43E-73 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0666 ae563129f764ad4394e2f48820b65500 399 SUPERFAMILY SSF51161 237 398 5.99E-34 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily Mlab_0666 ae563129f764ad4394e2f48820b65500 399 Gene3D G3DSA:3.90.550.10 1 230 1.0E-65 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0666 ae563129f764ad4394e2f48820b65500 399 Gene3D G3DSA:2.160.10.10 231 399 4.9E-42 T 23-10-2018 Mlab_0666 ae563129f764ad4394e2f48820b65500 399 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 388 3.3E-170 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 Mlab_0854 02c15caaea4762a44227db3f7c912d1c 134 Gene3D G3DSA:1.10.10.10 13 78 2.9E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0854 02c15caaea4762a44227db3f7c912d1c 134 SUPERFAMILY SSF47979 74 129 7.46E-14 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 Mlab_0854 02c15caaea4762a44227db3f7c912d1c 134 Gene3D G3DSA:1.10.60.10 79 133 3.5E-18 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 Mlab_0854 02c15caaea4762a44227db3f7c912d1c 134 SMART SM00529 35 133 2.5E-24 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 Mlab_0854 02c15caaea4762a44227db3f7c912d1c 134 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 13 71 2.7E-17 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 Mlab_0854 02c15caaea4762a44227db3f7c912d1c 134 SUPERFAMILY SSF46785 13 73 5.09E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0854 02c15caaea4762a44227db3f7c912d1c 134 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 74 129 2.2E-13 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 Mlab_1074 ecf9d6e890db7a9e78ddc6ab1502f747 380 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 15 204 3.1E-76 T 23-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 Mlab_1074 ecf9d6e890db7a9e78ddc6ab1502f747 380 Gene3D G3DSA:3.40.50.300 2 258 3.1E-74 T 23-10-2018 Mlab_1074 ecf9d6e890db7a9e78ddc6ab1502f747 380 SMART SM00382 31 219 1.8E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1074 ecf9d6e890db7a9e78ddc6ab1502f747 380 Pfam PF00005 ABC transporter 22 170 2.6E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1074 ecf9d6e890db7a9e78ddc6ab1502f747 380 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1074 ecf9d6e890db7a9e78ddc6ab1502f747 380 SUPERFAMILY SSF52540 3 239 3.06E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1223 3d9bd60a6b26faa77d92d7872f250ba0 458 PIRSF PIRSF039114 1 458 1.0E-235 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1223 3d9bd60a6b26faa77d92d7872f250ba0 458 SUPERFAMILY SSF52540 75 352 2.02E-81 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1223 3d9bd60a6b26faa77d92d7872f250ba0 458 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 129 347 1.9E-64 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Mlab_1223 3d9bd60a6b26faa77d92d7872f250ba0 458 Gene3D G3DSA:3.40.50.12240 12 458 1.5E-177 T 23-10-2018 Mlab_1223 3d9bd60a6b26faa77d92d7872f250ba0 458 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 1 457 59.098 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1223 3d9bd60a6b26faa77d92d7872f250ba0 458 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 338 347 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Mlab_1223 3d9bd60a6b26faa77d92d7872f250ba0 458 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 7 72 3.2E-10 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Mlab_1223 3d9bd60a6b26faa77d92d7872f250ba0 458 SUPERFAMILY SSF47917 359 415 2.12E-6 T 23-10-2018 Mlab_0410 f1c4cbdc10449059e01289e56968ff2c 472 SUPERFAMILY SSF88697 124 197 4.48E-16 T 23-10-2018 IPR015947 PUA-like superfamily Mlab_0410 f1c4cbdc10449059e01289e56968ff2c 472 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 242 413 3.2E-41 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 Mlab_0410 f1c4cbdc10449059e01289e56968ff2c 472 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 115 194 8.2E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 Mlab_0410 f1c4cbdc10449059e01289e56968ff2c 472 Gene3D G3DSA:2.30.130.10 121 197 1.7E-13 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 Mlab_0410 f1c4cbdc10449059e01289e56968ff2c 472 Gene3D G3DSA:3.40.50.620 211 418 4.4E-44 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0410 f1c4cbdc10449059e01289e56968ff2c 472 SUPERFAMILY SSF52402 219 402 4.19E-44 T 23-10-2018 Mlab_0410 f1c4cbdc10449059e01289e56968ff2c 472 SMART SM00359 124 198 4.1E-7 T 23-10-2018 IPR002478 PUA domain GO:0003723 Mlab_0410 f1c4cbdc10449059e01289e56968ff2c 472 Pfam PF01472 PUA domain 126 195 3.1E-12 T 23-10-2018 IPR002478 PUA domain GO:0003723 Mlab_0592 f6a1fe9538eda2b19b5bd9fb1f03abf9 329 Gene3D G3DSA:2.170.150.20 184 329 1.8E-51 T 23-10-2018 Mlab_0592 f6a1fe9538eda2b19b5bd9fb1f03abf9 329 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 17 166 9.1E-50 T 23-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Mlab_0592 f6a1fe9538eda2b19b5bd9fb1f03abf9 329 SUPERFAMILY SSF55068 10 170 3.79E-58 T 23-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Mlab_0592 f6a1fe9538eda2b19b5bd9fb1f03abf9 329 Pfam PF01625 Peptide methionine sulfoxide reductase 18 167 1.6E-55 T 23-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Mlab_0592 f6a1fe9538eda2b19b5bd9fb1f03abf9 329 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 15 172 33.143 T 23-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Mlab_0592 f6a1fe9538eda2b19b5bd9fb1f03abf9 329 SUPERFAMILY SSF51316 189 326 4.24E-52 T 23-10-2018 IPR011057 Mss4-like superfamily Mlab_0592 f6a1fe9538eda2b19b5bd9fb1f03abf9 329 Gene3D G3DSA:3.30.1060.10 1 179 1.4E-61 T 23-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Mlab_0592 f6a1fe9538eda2b19b5bd9fb1f03abf9 329 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 190 322 4.0E-55 T 23-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 Mlab_0592 f6a1fe9538eda2b19b5bd9fb1f03abf9 329 Pfam PF01641 SelR domain 195 313 7.7E-43 T 23-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 Gene3D G3DSA:3.10.580.10 60 121 4.0E-13 T 23-10-2018 Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 SUPERFAMILY SSF54631 2 121 4.93E-28 T 23-10-2018 Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 Gene3D G3DSA:3.10.580.10 1 59 7.9E-11 T 23-10-2018 Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 Gene3D G3DSA:3.10.580.10 265 381 4.6E-22 T 23-10-2018 Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 Pfam PF02195 ParB-like nuclease domain 408 482 1.2E-12 T 23-10-2018 IPR003115 ParB/Sulfiredoxin Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 Pfam PF02195 ParB-like nuclease domain 148 224 1.2E-9 T 23-10-2018 IPR003115 ParB/Sulfiredoxin Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 SUPERFAMILY SSF110849 144 303 1.26E-20 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 SMART SM00116 71 119 2.2E-6 T 23-10-2018 IPR000644 CBS domain Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 SMART SM00116 273 320 0.0025 T 23-10-2018 IPR000644 CBS domain Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 SMART SM00116 13 60 3.8E-7 T 23-10-2018 IPR000644 CBS domain Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 SMART SM00116 331 379 3.7E-4 T 23-10-2018 IPR000644 CBS domain Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 SUPERFAMILY SSF54631 259 377 2.02E-23 T 23-10-2018 Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 Pfam PF00571 CBS domain 328 377 5.2E-6 T 23-10-2018 IPR000644 CBS domain Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 Pfam PF00571 CBS domain 6 57 8.2E-10 T 23-10-2018 IPR000644 CBS domain Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 Pfam PF00571 CBS domain 66 117 1.9E-9 T 23-10-2018 IPR000644 CBS domain Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 Pfam PF00571 CBS domain 266 318 1.7E-6 T 23-10-2018 IPR000644 CBS domain Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 SMART SM00470 407 489 2.0E-12 T 23-10-2018 IPR003115 ParB/Sulfiredoxin Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 SMART SM00470 147 229 4.7E-11 T 23-10-2018 IPR003115 ParB/Sulfiredoxin Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 Gene3D G3DSA:3.90.1530.10 406 491 8.9E-8 T 23-10-2018 Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 Gene3D G3DSA:3.90.1530.10 139 232 9.7E-8 T 23-10-2018 Mlab_1295 4517a2c64841bd726064ee619ee2b147 512 SUPERFAMILY SSF110849 406 506 4.06E-19 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 Gene3D G3DSA:3.40.50.261 128 291 2.7E-55 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 Gene3D G3DSA:3.40.50.720 1 127 6.1E-42 T 23-10-2018 Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 Pfam PF02629 CoA binding domain 6 103 1.3E-19 T 23-10-2018 IPR003781 CoA-binding GO:0048037 Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 PIRSF PIRSF001553 1 291 1.8E-104 T 23-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 239 252 - T 23-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 PRINTS PR01798 Succinyl-CoA synthase signature 243 260 1.7E-25 T 23-10-2018 Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 1.7E-25 T 23-10-2018 Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 1.7E-25 T 23-10-2018 Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 1.7E-25 T 23-10-2018 Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 156 185 - T 23-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 SUPERFAMILY SSF52210 127 290 1.28E-41 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 SMART SM00881 3 104 3.1E-23 T 23-10-2018 IPR003781 CoA-binding GO:0048037 Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 291 35.717 T 23-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 SUPERFAMILY SSF51735 2 126 1.21E-31 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0488 08f81a3876e893b24e0deb1ca66778e6 291 Pfam PF00549 CoA-ligase 155 271 8.4E-10 T 23-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Mlab_0476 eea0a5c4dc7c36b53dcf9bd24a2ff1c7 303 ProSitePatterns PS00770 Aminotransferases class-IV signature. 198 226 - T 23-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 Mlab_0476 eea0a5c4dc7c36b53dcf9bd24a2ff1c7 303 Gene3D G3DSA:3.20.10.10 139 301 2.8E-47 T 23-10-2018 Mlab_0476 eea0a5c4dc7c36b53dcf9bd24a2ff1c7 303 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 20 295 3.0E-101 T 23-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 Mlab_0476 eea0a5c4dc7c36b53dcf9bd24a2ff1c7 303 Gene3D G3DSA:3.30.470.10 16 138 4.5E-54 T 23-10-2018 Mlab_0476 eea0a5c4dc7c36b53dcf9bd24a2ff1c7 303 SUPERFAMILY SSF56752 17 294 5.62E-87 T 23-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 Mlab_0476 eea0a5c4dc7c36b53dcf9bd24a2ff1c7 303 Pfam PF01063 Amino-transferase class IV 45 271 1.5E-50 T 23-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 Mlab_0848 8068a479cb349ce14347265e1ffe015a 649 TIGRFAM TIGR01863 cas_Csd1: CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG 5 625 1.7E-90 T 23-10-2018 IPR010144 CRISPR-associated protein, Csd1-type Mlab_0848 8068a479cb349ce14347265e1ffe015a 649 Pfam PF09709 CRISPR-associated protein (Cas_Csd1) 7 619 9.2E-132 T 23-10-2018 IPR010144 CRISPR-associated protein, Csd1-type Mlab_1513 6185026d98dbfe35846325704c113958 214 Gene3D G3DSA:3.20.20.140 1 197 1.4E-25 T 23-10-2018 Mlab_1513 6185026d98dbfe35846325704c113958 214 SMART SM00481 2 74 5.6E-16 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Mlab_1513 6185026d98dbfe35846325704c113958 214 SUPERFAMILY SSF89550 1 201 1.96E-37 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Mlab_0138 f5d5d65c7f9e36c0d947dd4460826cc0 500 SMART SM00878 338 444 6.6E-62 T 23-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Mlab_0138 f5d5d65c7f9e36c0d947dd4460826cc0 500 SUPERFAMILY SSF56059 89 351 8.66E-72 T 23-10-2018 Mlab_0138 f5d5d65c7f9e36c0d947dd4460826cc0 500 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Mlab_0138 f5d5d65c7f9e36c0d947dd4460826cc0 500 Pfam PF02785 Biotin carboxylase C-terminal domain 338 444 1.1E-38 T 23-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Mlab_0138 f5d5d65c7f9e36c0d947dd4460826cc0 500 Gene3D G3DSA:3.30.470.130 1 450 9.2E-194 T 23-10-2018 Mlab_0138 f5d5d65c7f9e36c0d947dd4460826cc0 500 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 7 446 4.6E-189 T 23-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 Mlab_0138 f5d5d65c7f9e36c0d947dd4460826cc0 500 Pfam PF00289 Biotin carboxylase, N-terminal domain 7 115 2.5E-45 T 23-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Mlab_0138 f5d5d65c7f9e36c0d947dd4460826cc0 500 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 123 324 3.5E-77 T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Mlab_0138 f5d5d65c7f9e36c0d947dd4460826cc0 500 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Mlab_0138 f5d5d65c7f9e36c0d947dd4460826cc0 500 SUPERFAMILY SSF52440 4 118 3.38E-48 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Mlab_0138 f5d5d65c7f9e36c0d947dd4460826cc0 500 SUPERFAMILY SSF51246 333 445 5.23E-42 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 317 328 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 Pfam PF13187 4Fe-4S dicluster domain 608 656 1.6E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 SUPERFAMILY SSF54862 573 665 1.22E-15 T 23-10-2018 Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 Gene3D G3DSA:3.50.50.60 157 240 4.8E-9 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 Gene3D G3DSA:3.30.70.3270 245 373 1.9E-11 T 23-10-2018 Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 SUPERFAMILY SSF51905 151 584 2.07E-24 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 608 619 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 Pfam PF12838 4Fe-4S dicluster domain 270 329 8.5E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 SUPERFAMILY SSF54862 270 330 1.07E-8 T 23-10-2018 Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 270 281 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 158 581 7.5E-13 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 Gene3D G3DSA:3.30.70.20 566 671 1.2E-12 T 23-10-2018 Mlab_0241 420ab08d5a6a83e792b2d79d963ea1fd 679 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 641 652 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_1282 2de10da2160fa980dd418e20c0d2a707 142 Pfam PF04027 Domain of unknown function (DUF371) 7 139 4.8E-49 T 23-10-2018 IPR007171 Protein of unknown function DUF371 Mlab_1282 2de10da2160fa980dd418e20c0d2a707 142 Gene3D G3DSA:2.60.120.630 1 142 7.3E-50 T 23-10-2018 IPR023131 Mth639-like domain superfamily Mlab_0173 e5e2c1990e7441c117a80cd416c3703e 127 SUPERFAMILY SSF49367 40 126 4.84E-28 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 Mlab_0173 e5e2c1990e7441c117a80cd416c3703e 127 SUPERFAMILY SSF57802 4 37 3.53E-11 T 23-10-2018 Mlab_0173 e5e2c1990e7441c117a80cd416c3703e 127 Gene3D G3DSA:2.20.28.100 1 39 5.5E-16 T 23-10-2018 IPR038094 Desulforodoxin domain superfamily Mlab_0173 e5e2c1990e7441c117a80cd416c3703e 127 Pfam PF06397 Desulfoferrodoxin, N-terminal domain 3 37 1.2E-16 T 23-10-2018 IPR004462 Desulforodoxin domain GO:0005506 Mlab_0173 e5e2c1990e7441c117a80cd416c3703e 127 TIGRFAM TIGR00319 desulf_FeS4: desulfoferrodoxin FeS4 iron-binding domain 1 34 1.3E-16 T 23-10-2018 IPR004462 Desulforodoxin domain GO:0005506 Mlab_0173 e5e2c1990e7441c117a80cd416c3703e 127 Gene3D G3DSA:2.60.40.730 40 126 9.8E-27 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 Mlab_0173 e5e2c1990e7441c117a80cd416c3703e 127 Pfam PF01880 Desulfoferrodoxin 43 125 1.2E-17 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 Mlab_0173 e5e2c1990e7441c117a80cd416c3703e 127 TIGRFAM TIGR00320 dfx_rbo: desulfoferrodoxin 1 124 8.8E-47 T 23-10-2018 IPR004793 Desulfoferrodoxin GO:0005506|GO:0019430 Mlab_0713 c176d6efdbf39c19bceb2f44dfdc2b6c 89 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 86 1.0E-21 T 23-10-2018 Mlab_0713 c176d6efdbf39c19bceb2f44dfdc2b6c 89 PIRSF PIRSF028732 1 89 7.4E-31 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 Mlab_0713 c176d6efdbf39c19bceb2f44dfdc2b6c 89 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 3 88 1.2E-33 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 Mlab_0713 c176d6efdbf39c19bceb2f44dfdc2b6c 89 SUPERFAMILY SSF82704 4 88 3.92E-20 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 Mlab_0713 c176d6efdbf39c19bceb2f44dfdc2b6c 89 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 88 21.766 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 Mlab_0713 c176d6efdbf39c19bceb2f44dfdc2b6c 89 Pfam PF01918 Alba 4 64 6.9E-16 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 Mlab_0713 c176d6efdbf39c19bceb2f44dfdc2b6c 89 Gene3D G3DSA:3.30.110.20 1 88 2.1E-30 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 Mlab_0090 cce8aa3239dffefa82740538a0743087 108 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 3 107 32.03 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0090 cce8aa3239dffefa82740538a0743087 108 Pfam PF00366 Ribosomal protein S17 36 104 8.0E-25 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0090 cce8aa3239dffefa82740538a0743087 108 PRINTS PR00973 Ribosomal protein S17 family signature 83 93 6.8E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0090 cce8aa3239dffefa82740538a0743087 108 PRINTS PR00973 Ribosomal protein S17 family signature 50 73 6.8E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0090 cce8aa3239dffefa82740538a0743087 108 PRINTS PR00973 Ribosomal protein S17 family signature 93 100 6.8E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0090 cce8aa3239dffefa82740538a0743087 108 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 5 105 3.5E-44 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0090 cce8aa3239dffefa82740538a0743087 108 Gene3D G3DSA:2.40.50.1000 1 108 3.8E-40 T 23-10-2018 Mlab_0090 cce8aa3239dffefa82740538a0743087 108 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 33 103 1.0E-24 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0090 cce8aa3239dffefa82740538a0743087 108 SUPERFAMILY SSF50249 30 107 6.43E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 PRINTS PR00415 Aconitase family signature 198 211 1.1E-17 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 PRINTS PR00415 Aconitase family signature 184 197 1.1E-17 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 PRINTS PR00415 Aconitase family signature 108 121 1.1E-17 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 PRINTS PR00415 Aconitase family signature 122 137 1.1E-17 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 PRINTS PR00415 Aconitase family signature 345 358 1.1E-17 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 Pfam PF00330 Aconitase family (aconitate hydratase) 17 403 1.3E-81 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 16 408 2.8E-138 T 23-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 6 409 1.5E-141 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 5 411 42.188 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 Gene3D G3DSA:3.30.499.20 6 265 2.1E-75 T 23-10-2018 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 ProSitePatterns PS01244 Aconitase family signature 2. 345 358 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 Gene3D G3DSA:3.30.499.10 268 416 3.5E-49 T 23-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Mlab_0233 993df4c00e7f2b04b09178a771fc9a8a 417 SUPERFAMILY SSF53732 7 411 1.06E-124 T 23-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Mlab_1183 fd08eb04d43cc3c4b746657063022303 352 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 12 341 2.5E-44 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Mlab_1183 fd08eb04d43cc3c4b746657063022303 352 Pfam PF00145 C-5 cytosine-specific DNA methylase 12 346 3.4E-57 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Mlab_1183 fd08eb04d43cc3c4b746657063022303 352 Gene3D G3DSA:3.40.50.150 12 340 4.5E-77 T 23-10-2018 Mlab_1183 fd08eb04d43cc3c4b746657063022303 352 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 164 177 1.1E-11 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Mlab_1183 fd08eb04d43cc3c4b746657063022303 352 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 119 133 1.1E-11 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Mlab_1183 fd08eb04d43cc3c4b746657063022303 352 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 10 26 1.1E-11 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Mlab_1183 fd08eb04d43cc3c4b746657063022303 352 SUPERFAMILY SSF53335 8 347 8.67E-80 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1183 fd08eb04d43cc3c4b746657063022303 352 Gene3D G3DSA:3.90.120.10 160 335 4.5E-77 T 23-10-2018 Mlab_1390 c1336a40f811ae1a5aa6fa7274116332 281 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 54 240 2.3E-33 T 23-10-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 Mlab_1390 c1336a40f811ae1a5aa6fa7274116332 281 Pfam PF02361 Cobalt transport protein 17 244 5.8E-28 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component Mlab_1552 db5c0f7b06a5c414d83925c678358726 716 SUPERFAMILY SSF48452 541 658 4.56E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1552 db5c0f7b06a5c414d83925c678358726 716 Gene3D G3DSA:1.25.40.10 519 707 9.3E-18 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1552 db5c0f7b06a5c414d83925c678358726 716 Gene3D G3DSA:1.25.40.10 238 376 5.7E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1552 db5c0f7b06a5c414d83925c678358726 716 Pfam PF13432 Tetratricopeptide repeat 589 647 2.0E-4 T 23-10-2018 Mlab_1552 db5c0f7b06a5c414d83925c678358726 716 SMART SM00028 582 615 0.088 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1552 db5c0f7b06a5c414d83925c678358726 716 SMART SM00028 616 649 0.034 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1552 db5c0f7b06a5c414d83925c678358726 716 SMART SM00028 545 578 0.024 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1552 db5c0f7b06a5c414d83925c678358726 716 SMART SM00028 271 304 320.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0963 fc5f0bbcab2738798f9bb6f01222a948 492 SUPERFAMILY SSF53300 322 461 4.11E-18 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Mlab_0963 fc5f0bbcab2738798f9bb6f01222a948 492 SMART SM00327 321 483 0.001 T 23-10-2018 IPR002035 von Willebrand factor, type A Mlab_0963 fc5f0bbcab2738798f9bb6f01222a948 492 Gene3D G3DSA:3.40.50.410 320 480 2.5E-8 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Mlab_0079 94b79fbaec7a74693e505ccfcc4c11b6 280 Gene3D G3DSA:3.40.50.10830 1 140 6.3E-34 T 23-10-2018 Mlab_0079 94b79fbaec7a74693e505ccfcc4c11b6 280 Hamap MF_00058 F420-dependent methylenetetrahydromethanopterin dehydrogenase [mtd]. 1 280 38.018 T 23-10-2018 IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 Mlab_0079 94b79fbaec7a74693e505ccfcc4c11b6 280 SUPERFAMILY SSF102324 1 280 3.66E-112 T 23-10-2018 IPR036080 F420-dependent methylenetetrahydromethanopterin dehydrogenase superfamily GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 Mlab_0079 94b79fbaec7a74693e505ccfcc4c11b6 280 Pfam PF01993 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase 3 280 1.5E-117 T 23-10-2018 IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 Mlab_0079 94b79fbaec7a74693e505ccfcc4c11b6 280 ProDom PD017604 DEHYDROGENASE METHYLENETETRAHYDROMETHANOPTERIN F420-DEPENDENT MTD COENZYME DEPENDENT F420 N5N10- ONE-CARBON METABOLISM 9 280 4.0E-110 T 23-10-2018 IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 Mlab_0462 1ed4a2dbf71cb36d58343465cf3b1385 414 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 7 82 1.4E-19 T 23-10-2018 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal Mlab_0462 1ed4a2dbf71cb36d58343465cf3b1385 414 SUPERFAMILY SSF46548 256 356 6.8E-13 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Mlab_0462 1ed4a2dbf71cb36d58343465cf3b1385 414 Pfam PF13534 4Fe-4S dicluster domain 291 356 6.1E-6 T 23-10-2018 Mlab_0462 1ed4a2dbf71cb36d58343465cf3b1385 414 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 341 352 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0462 1ed4a2dbf71cb36d58343465cf3b1385 414 Gene3D G3DSA:3.40.50.2030 252 286 1.2E-5 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_0462 1ed4a2dbf71cb36d58343465cf3b1385 414 Gene3D G3DSA:1.10.1060.10 287 367 1.2E-5 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Mlab_0462 1ed4a2dbf71cb36d58343465cf3b1385 414 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 92 247 2.0E-35 T 23-10-2018 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal Mlab_1710 e5bfa87329171b4c7ecdf158beb926ee 289 SUPERFAMILY SSF46689 13 70 4.51E-13 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Mlab_1710 e5bfa87329171b4c7ecdf158beb926ee 289 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 58 9.8E-7 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Mlab_1710 e5bfa87329171b4c7ecdf158beb926ee 289 Gene3D G3DSA:1.10.357.10 8 188 2.5E-44 T 23-10-2018 Mlab_0673 a304e0d15adcdde9461655471811a7c9 738 Pfam PF00270 DEAD/DEAH box helicase 46 213 7.9E-24 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Mlab_0673 a304e0d15adcdde9461655471811a7c9 738 Gene3D G3DSA:3.40.50.300 240 388 2.3E-23 T 23-10-2018 Mlab_0673 a304e0d15adcdde9461655471811a7c9 738 SMART SM00487 39 245 3.6E-25 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Mlab_0673 a304e0d15adcdde9461655471811a7c9 738 SUPERFAMILY SSF52540 52 373 1.47E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0673 a304e0d15adcdde9461655471811a7c9 738 SMART SM00490 281 364 2.0E-15 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0673 a304e0d15adcdde9461655471811a7c9 738 Pfam PF00271 Helicase conserved C-terminal domain 258 363 1.0E-14 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0673 a304e0d15adcdde9461655471811a7c9 738 Gene3D G3DSA:3.40.50.300 22 227 2.1E-38 T 23-10-2018 Mlab_0673 a304e0d15adcdde9461655471811a7c9 738 Pfam PF09369 Domain of unknown function (DUF1998) 619 697 8.0E-20 T 23-10-2018 IPR018973 DEAD/DEAH-box helicase, putative Mlab_0989 975fdcc9268c022cfa25e80ca46d77b5 398 TIGRFAM TIGR00836 amt: ammonium transporter 7 396 9.6E-128 T 23-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 Mlab_0989 975fdcc9268c022cfa25e80ca46d77b5 398 Gene3D G3DSA:1.10.3430.10 2 397 3.7E-137 T 23-10-2018 IPR029020 Ammonium/urea transporter Mlab_0989 975fdcc9268c022cfa25e80ca46d77b5 398 SUPERFAMILY SSF111352 2 379 1.19E-114 T 23-10-2018 Mlab_0989 975fdcc9268c022cfa25e80ca46d77b5 398 Pfam PF00909 Ammonium Transporter Family 8 396 9.7E-117 T 23-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 Mlab_0989 975fdcc9268c022cfa25e80ca46d77b5 398 ProSitePatterns PS01219 Ammonium transporters signature. 157 182 - T 23-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 Mlab_1423 32e242bbc72456cd55f79685d2454443 259 SUPERFAMILY SSF53448 1 255 2.5E-66 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1423 32e242bbc72456cd55f79685d2454443 259 Gene3D G3DSA:3.90.550.10 1 258 4.0E-72 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1423 32e242bbc72456cd55f79685d2454443 259 Pfam PF00483 Nucleotidyl transferase 3 202 1.1E-18 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Mlab_1423 32e242bbc72456cd55f79685d2454443 259 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 257 4.2E-124 T 23-10-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 Mlab_0298 17c2c70f4b89b7caef0edf8315aa9938 178 Pfam PF13302 Acetyltransferase (GNAT) domain 6 144 5.4E-30 T 23-10-2018 IPR000182 GNAT domain Mlab_0298 17c2c70f4b89b7caef0edf8315aa9938 178 SUPERFAMILY SSF55729 1 168 2.95E-41 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_0298 17c2c70f4b89b7caef0edf8315aa9938 178 Gene3D G3DSA:3.40.630.30 1 156 1.4E-42 T 23-10-2018 Mlab_1043 5da0f92dfe73bbd4b7318d9f03c620e4 334 Pfam PF01032 FecCD transport family 18 328 1.1E-90 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Mlab_1043 5da0f92dfe73bbd4b7318d9f03c620e4 334 Gene3D G3DSA:1.10.3470.10 2 333 3.2E-103 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_1043 5da0f92dfe73bbd4b7318d9f03c620e4 334 SUPERFAMILY SSF81345 7 328 1.83E-78 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 ProSitePatterns PS00211 ABC transporters family signature. 451 465 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 Gene3D G3DSA:3.40.50.300 326 585 8.9E-50 T 23-10-2018 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 32 1.2E-10 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 Gene3D G3DSA:3.40.50.300 1 324 6.3E-65 T 23-10-2018 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 PRINTS PR01868 ABC transporter family E signature 19 34 1.3E-52 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 PRINTS PR01868 ABC transporter family E signature 46 70 1.3E-52 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 PRINTS PR01868 ABC transporter family E signature 149 175 1.3E-52 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 PRINTS PR01868 ABC transporter family E signature 100 125 1.3E-52 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 PRINTS PR01868 ABC transporter family E signature 72 92 1.3E-52 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 PRINTS PR01868 ABC transporter family E signature 133 149 1.3E-52 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 SMART SM00382 361 528 2.4E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 SMART SM00382 95 286 1.1E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 SUPERFAMILY SSF54862 4 87 2.65E-15 T 23-10-2018 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 Pfam PF00005 ABC transporter 358 479 9.6E-20 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 Pfam PF00005 ABC transporter 95 237 1.8E-15 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 Pfam PF00037 4Fe-4S binding domain 43 64 1.0E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 SUPERFAMILY SSF52540 358 526 9.61E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0542 9c9795787de3b4e2117c009de03054a4 600 SUPERFAMILY SSF52540 84 280 1.09E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0404 c9ba337e8be85d4e13c808c206c7ad34 605 Gene3D G3DSA:3.30.300.30 490 592 6.3E-28 T 23-10-2018 Mlab_0404 c9ba337e8be85d4e13c808c206c7ad34 605 Gene3D G3DSA:3.40.50.980 85 410 4.5E-114 T 23-10-2018 Mlab_0404 c9ba337e8be85d4e13c808c206c7ad34 605 SUPERFAMILY SSF56801 72 589 2.62E-143 T 23-10-2018 Mlab_0404 c9ba337e8be85d4e13c808c206c7ad34 605 ProSitePatterns PS00455 Putative AMP-binding domain signature. 245 256 - T 23-10-2018 IPR020845 AMP-binding, conserved site Mlab_0404 c9ba337e8be85d4e13c808c206c7ad34 605 Gene3D G3DSA:2.30.38.10 411 489 4.5E-114 T 23-10-2018 Mlab_0404 c9ba337e8be85d4e13c808c206c7ad34 605 Pfam PF13193 AMP-binding enzyme C-terminal domain 505 580 1.8E-15 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Mlab_0404 c9ba337e8be85d4e13c808c206c7ad34 605 Gene3D G3DSA:3.40.50.980 87 261 4.5E-114 T 23-10-2018 Mlab_0404 c9ba337e8be85d4e13c808c206c7ad34 605 Pfam PF00501 AMP-binding enzyme 84 496 1.0E-100 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Mlab_1254 75cab0d6c07696134619c7952e3be31b 203 Gene3D G3DSA:3.40.50.150 16 200 1.8E-56 T 23-10-2018 Mlab_1254 75cab0d6c07696134619c7952e3be31b 203 PIRSF PIRSF005461 1 203 3.6E-61 T 23-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 Mlab_1254 75cab0d6c07696134619c7952e3be31b 203 SUPERFAMILY SSF53335 18 192 2.2E-33 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1254 75cab0d6c07696134619c7952e3be31b 203 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 3 192 27.276 T 23-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 Mlab_1254 75cab0d6c07696134619c7952e3be31b 203 Pfam PF01728 FtsJ-like methyltransferase 19 191 5.9E-53 T 23-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 SUPERFAMILY SSF52540 2 1133 1.35E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 2 1146 1.9E-288 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 Gene3D G3DSA:1.10.601.10 685 894 5.3E-5 T 23-10-2018 Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1135 1.8E-62 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 Gene3D G3DSA:3.40.50.300 995 1148 1.7E-40 T 23-10-2018 Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 Gene3D G3DSA:3.30.70.1620 568 647 3.0E-43 T 23-10-2018 Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1149 19.397 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 SUPERFAMILY SSF75553 473 648 4.71E-45 T 23-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 PIRSF PIRSF005719 1 1147 1.4E-223 T 23-10-2018 IPR024704 Structural maintenance of chromosomes protein Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 SMART SM00968 507 622 1.6E-39 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 Pfam PF06470 SMC proteins Flexible Hinge Domain 507 621 1.9E-27 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 Gene3D G3DSA:1.20.1060.20 505 649 3.0E-43 T 23-10-2018 Mlab_1012 d0ac3af4126b9844f39a4bbdd1c7fd2a 1149 Gene3D G3DSA:3.40.50.300 1 169 8.9E-43 T 23-10-2018 Mlab_0451 2d5a5281b38db82409dd6a6be5df7b7b 502 Pfam PF00571 CBS domain 379 433 8.2E-9 T 23-10-2018 IPR000644 CBS domain Mlab_0451 2d5a5281b38db82409dd6a6be5df7b7b 502 Pfam PF00571 CBS domain 442 492 4.6E-8 T 23-10-2018 IPR000644 CBS domain Mlab_0451 2d5a5281b38db82409dd6a6be5df7b7b 502 SMART SM00116 386 434 6.8E-7 T 23-10-2018 IPR000644 CBS domain Mlab_0451 2d5a5281b38db82409dd6a6be5df7b7b 502 SMART SM00116 449 497 8.0E-5 T 23-10-2018 IPR000644 CBS domain Mlab_0451 2d5a5281b38db82409dd6a6be5df7b7b 502 ProDom PD011569 METAL-BINDING IRON IRON-SULFUR 4FE-4S FERREDOXIN OXIDOREDUCTASE DOMAIN ELECTRON METHANOGENESIS A 18 313 1.0E-108 T 23-10-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation Mlab_0451 2d5a5281b38db82409dd6a6be5df7b7b 502 Gene3D G3DSA:3.10.580.10 377 499 8.9E-30 T 23-10-2018 Mlab_0451 2d5a5281b38db82409dd6a6be5df7b7b 502 Pfam PF01837 Homocysteine biosynthesis enzyme, sulfur-incorporation 18 354 1.2E-141 T 23-10-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation Mlab_0451 2d5a5281b38db82409dd6a6be5df7b7b 502 SUPERFAMILY SSF54631 379 492 1.95E-28 T 23-10-2018 Mlab_1236 51982ccf0dc326131838e647f862ff60 217 Gene3D G3DSA:1.10.10.10 4 98 7.3E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1236 51982ccf0dc326131838e647f862ff60 217 SUPERFAMILY SSF46785 146 209 6.17E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1236 51982ccf0dc326131838e647f862ff60 217 SMART SM00418 9 87 1.6E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_1236 51982ccf0dc326131838e647f862ff60 217 Pfam PF01022 Bacterial regulatory protein, arsR family 18 59 4.8E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_1236 51982ccf0dc326131838e647f862ff60 217 SUPERFAMILY SSF46785 5 133 8.12E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1236 51982ccf0dc326131838e647f862ff60 217 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 151 201 1.1E-6 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal Mlab_0634 48c081a1d89163767e0324974af04722 433 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 11 421 7.3E-145 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0634 48c081a1d89163767e0324974af04722 433 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 18 426 39.281 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0634 48c081a1d89163767e0324974af04722 433 Gene3D G3DSA:2.40.37.10 17 421 2.5E-143 T 23-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Mlab_0634 48c081a1d89163767e0324974af04722 433 Gene3D G3DSA:3.20.20.10 37 289 2.5E-143 T 23-10-2018 IPR029066 PLP-binding barrel Mlab_0634 48c081a1d89163767e0324974af04722 433 PRINTS PR01181 Diaminopimelate decarboxylase signature 80 97 5.7E-25 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0634 48c081a1d89163767e0324974af04722 433 PRINTS PR01181 Diaminopimelate decarboxylase signature 168 177 5.7E-25 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0634 48c081a1d89163767e0324974af04722 433 PRINTS PR01181 Diaminopimelate decarboxylase signature 311 329 5.7E-25 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0634 48c081a1d89163767e0324974af04722 433 PRINTS PR01181 Diaminopimelate decarboxylase signature 393 415 5.7E-25 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0634 48c081a1d89163767e0324974af04722 433 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 194 207 1.1E-19 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Mlab_0634 48c081a1d89163767e0324974af04722 433 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 284 303 1.1E-19 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Mlab_0634 48c081a1d89163767e0324974af04722 433 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 383 396 1.1E-19 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Mlab_0634 48c081a1d89163767e0324974af04722 433 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 62 80 1.1E-19 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Mlab_0634 48c081a1d89163767e0324974af04722 433 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 82 94 1.1E-19 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Mlab_0634 48c081a1d89163767e0324974af04722 433 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 294 383 3.5E-24 T 23-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Mlab_0634 48c081a1d89163767e0324974af04722 433 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 45 293 3.2E-52 T 23-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Mlab_0634 48c081a1d89163767e0324974af04722 433 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 62 80 - T 23-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Mlab_0634 48c081a1d89163767e0324974af04722 433 SUPERFAMILY SSF50621 278 423 7.95E-51 T 23-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Mlab_0634 48c081a1d89163767e0324974af04722 433 SUPERFAMILY SSF51419 29 296 7.71E-73 T 23-10-2018 IPR029066 PLP-binding barrel Mlab_1417 d08e33238d8fb5080a9986ccbe52a360 385 SUPERFAMILY SSF52518 1 249 1.96E-67 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_1417 d08e33238d8fb5080a9986ccbe52a360 385 Gene3D G3DSA:3.40.50.920 253 380 6.0E-42 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Mlab_1417 d08e33238d8fb5080a9986ccbe52a360 385 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 18 238 5.3E-70 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Mlab_1417 d08e33238d8fb5080a9986ccbe52a360 385 Gene3D G3DSA:3.40.50.970 1 250 5.1E-98 T 23-10-2018 Mlab_1417 d08e33238d8fb5080a9986ccbe52a360 385 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 261 362 1.8E-32 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II Mlab_1417 d08e33238d8fb5080a9986ccbe52a360 385 SUPERFAMILY SSF52922 255 372 6.02E-32 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Mlab_0941 00358b303c9553c964b97cf42d707c95 497 SUPERFAMILY SSF52335 3 187 9.39E-62 T 23-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Mlab_0941 00358b303c9553c964b97cf42d707c95 497 Pfam PF02142 MGS-like domain 13 124 1.3E-21 T 23-10-2018 IPR011607 Methylglyoxal synthase-like domain Mlab_0941 00358b303c9553c964b97cf42d707c95 497 Gene3D G3DSA:3.40.140.20 361 497 1.0E-55 T 23-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Mlab_0941 00358b303c9553c964b97cf42d707c95 497 PIRSF PIRSF000414 1 497 5.9E-192 T 23-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Mlab_0941 00358b303c9553c964b97cf42d707c95 497 Gene3D G3DSA:3.40.140.20 200 346 4.9E-50 T 23-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Mlab_0941 00358b303c9553c964b97cf42d707c95 497 SUPERFAMILY SSF53927 204 497 8.02E-114 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Mlab_0941 00358b303c9553c964b97cf42d707c95 497 SMART SM00851 13 125 1.7E-49 T 23-10-2018 IPR011607 Methylglyoxal synthase-like domain Mlab_0941 00358b303c9553c964b97cf42d707c95 497 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 497 41.032 T 23-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Mlab_0941 00358b303c9553c964b97cf42d707c95 497 SMART SM00798 130 429 2.0E-153 T 23-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Mlab_0941 00358b303c9553c964b97cf42d707c95 497 Pfam PF01808 AICARFT/IMPCHase bienzyme 130 428 4.2E-109 T 23-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Mlab_0941 00358b303c9553c964b97cf42d707c95 497 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 497 3.1E-186 T 23-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Mlab_0941 00358b303c9553c964b97cf42d707c95 497 Gene3D G3DSA:3.40.50.1380 1 191 1.4E-78 T 23-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Mlab_1028 2bf71d1b99aca3f1fd49b2ce9dd97b4c 394 Pfam PF00149 Calcineurin-like phosphoesterase 134 283 5.7E-10 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Mlab_1028 2bf71d1b99aca3f1fd49b2ce9dd97b4c 394 SUPERFAMILY SSF49363 60 102 6.15E-10 T 23-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 Mlab_1028 2bf71d1b99aca3f1fd49b2ce9dd97b4c 394 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 63 102 2.3E-9 T 23-10-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 Mlab_1028 2bf71d1b99aca3f1fd49b2ce9dd97b4c 394 SUPERFAMILY SSF56300 109 344 7.21E-38 T 23-10-2018 Mlab_1028 2bf71d1b99aca3f1fd49b2ce9dd97b4c 394 Gene3D G3DSA:2.60.40.380 28 105 3.5E-7 T 23-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 Mlab_1028 2bf71d1b99aca3f1fd49b2ce9dd97b4c 394 Gene3D G3DSA:3.60.21.10 106 356 5.4E-31 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like Mlab_1149 6369a8e2ce6e21e65524e376ac0c44f9 238 Gene3D G3DSA:3.10.50.40 6 143 8.7E-40 T 23-10-2018 Mlab_1149 6369a8e2ce6e21e65524e376ac0c44f9 238 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 97 2.9E-8 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Mlab_1149 6369a8e2ce6e21e65524e376ac0c44f9 238 Gene3D G3DSA:3.30.70.2210 148 229 9.6E-6 T 23-10-2018 Mlab_1149 6369a8e2ce6e21e65524e376ac0c44f9 238 Gene3D G3DSA:2.40.10.330 89 129 8.7E-40 T 23-10-2018 Mlab_1149 6369a8e2ce6e21e65524e376ac0c44f9 238 SUPERFAMILY SSF54534 3 147 3.14E-27 T 23-10-2018 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Gene3D G3DSA:3.30.1490.180 350 422 2.0E-68 T 23-10-2018 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Gene3D G3DSA:1.10.274.100 497 652 6.8E-88 T 23-10-2018 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Gene3D G3DSA:1.20.120.1280 1 120 4.4E-30 T 23-10-2018 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Gene3D G3DSA:1.20.120.1280 230 280 1.1E-11 T 23-10-2018 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 SMART SM00663 207 519 3.6E-172 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Pfam PF04983 RNA polymerase Rpb1, domain 3 494 660 2.9E-28 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Pfam PF05000 RNA polymerase Rpb1, domain 4 686 791 2.5E-31 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Gene3D G3DSA:2.20.25.410 837 887 2.9E-20 T 23-10-2018 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 5 880 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Gene3D G3DSA:2.40.40.20 307 486 2.0E-68 T 23-10-2018 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Pfam PF04997 RNA polymerase Rpb1, domain 1 5 315 1.6E-101 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Pfam PF04998 RNA polymerase Rpb1, domain 5 798 863 2.9E-28 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Pfam PF00623 RNA polymerase Rpb1, domain 2 317 490 8.9E-62 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 SUPERFAMILY SSF64484 3 869 1.56E-298 T 23-10-2018 Mlab_1161 75f756fb556126eda11a27b16e63337a 889 Gene3D G3DSA:1.10.132.30 653 799 6.8E-88 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1426 e12112ffb7d2cdba90c45682205c4a4b 282 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 224 2.0E-28 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Mlab_1426 e12112ffb7d2cdba90c45682205c4a4b 282 SUPERFAMILY SSF51735 1 280 3.56E-48 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1426 e12112ffb7d2cdba90c45682205c4a4b 282 Gene3D G3DSA:3.90.25.10 174 267 7.4E-44 T 23-10-2018 Mlab_1426 e12112ffb7d2cdba90c45682205c4a4b 282 Gene3D G3DSA:3.40.50.720 3 280 7.4E-44 T 23-10-2018 Mlab_1372 e589477912947c5b1cedeecfa1e955ed 335 SUPERFAMILY SSF53807 25 298 2.86E-68 T 23-10-2018 Mlab_1372 e589477912947c5b1cedeecfa1e955ed 335 Gene3D G3DSA:3.40.50.1980 162 298 2.8E-33 T 23-10-2018 Mlab_1372 e589477912947c5b1cedeecfa1e955ed 335 Gene3D G3DSA:3.40.50.1980 43 161 9.7E-37 T 23-10-2018 Mlab_1372 e589477912947c5b1cedeecfa1e955ed 335 Pfam PF01497 Periplasmic binding protein 46 276 2.0E-42 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain Mlab_1480 74aa2ae34c46ebef0467589c8d52ac9a 50 SUPERFAMILY SSF48662 5 50 2.48E-17 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily Mlab_1480 74aa2ae34c46ebef0467589c8d52ac9a 50 Gene3D G3DSA:1.10.1620.10 1 49 7.8E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily Mlab_1480 74aa2ae34c46ebef0467589c8d52ac9a 50 ProSitePatterns PS00051 Ribosomal protein L39e signature. 29 45 - T 23-10-2018 IPR020083 Ribosomal protein L39e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1480 74aa2ae34c46ebef0467589c8d52ac9a 50 Pfam PF00832 Ribosomal L39 protein 8 49 1.6E-21 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1480 74aa2ae34c46ebef0467589c8d52ac9a 50 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 50 16.58 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1548 ed56372c8bf45dd56f5f762651b42b6d 286 Pfam PF00005 ABC transporter 19 158 6.7E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1548 ed56372c8bf45dd56f5f762651b42b6d 286 SUPERFAMILY SSF52540 5 223 1.55E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1548 ed56372c8bf45dd56f5f762651b42b6d 286 Gene3D G3DSA:3.40.50.300 2 247 1.4E-46 T 23-10-2018 Mlab_1548 ed56372c8bf45dd56f5f762651b42b6d 286 SMART SM00382 28 214 1.4E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1087 22ba1543082a0e3fabc6ad451f10fce1 144 SUPERFAMILY SSF118196 5 136 3.53E-41 T 23-10-2018 IPR036413 YaeB-like superfamily Mlab_1087 22ba1543082a0e3fabc6ad451f10fce1 144 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 5 139 7.3E-43 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain Mlab_1087 22ba1543082a0e3fabc6ad451f10fce1 144 Pfam PF01980 Uncharacterised protein family UPF0066 23 135 1.3E-31 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain Mlab_1087 22ba1543082a0e3fabc6ad451f10fce1 144 Gene3D G3DSA:2.40.30.70 6 144 1.3E-42 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 Pfam PF02110 Hydroxyethylthiazole kinase family 9 252 9.5E-83 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 9 253 5.3E-87 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 Gene3D G3DSA:3.40.1190.20 1 263 2.2E-97 T 23-10-2018 IPR029056 Ribokinase-like Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 SUPERFAMILY SSF53613 7 261 3.27E-60 T 23-10-2018 IPR029056 Ribokinase-like Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 10 255 32.182 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 29 50 1.1E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 16 23 1.1E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 117 131 1.1E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 161 178 1.1E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 60 68 1.1E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 86 103 1.1E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1656 99f11a32274ad72472bfab5648ce63e7 264 PIRSF PIRSF000513 2 263 2.2E-90 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_0527 6040c9f850b20cdb37203266a69bc119 429 Pfam PF04326 Putative DNA-binding domain 42 157 3.8E-18 T 23-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 Mlab_0527 6040c9f850b20cdb37203266a69bc119 429 Gene3D G3DSA:3.30.950.30 29 163 1.8E-19 T 23-10-2018 IPR038461 Schlafen, AAA domain superfamily Mlab_1353 96e31ee15417241bbfca2e653d6ce66a 251 Gene3D G3DSA:3.40.50.620 11 247 9.7E-71 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_1353 96e31ee15417241bbfca2e653d6ce66a 251 TIGRFAM TIGR00552 nadE: NAD+ synthetase 15 244 5.4E-67 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 Mlab_1353 96e31ee15417241bbfca2e653d6ce66a 251 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 8 248 43.299 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 Mlab_1353 96e31ee15417241bbfca2e653d6ce66a 251 SUPERFAMILY SSF52402 15 246 4.19E-62 T 23-10-2018 Mlab_1353 96e31ee15417241bbfca2e653d6ce66a 251 Pfam PF02540 NAD synthase 13 244 1.8E-68 T 23-10-2018 IPR022310 NAD/GMP synthase Mlab_0992 94ca468717f9dcf4373ae424b7cf840d 175 Gene3D G3DSA:3.40.109.10 7 175 1.6E-49 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Mlab_0992 94ca468717f9dcf4373ae424b7cf840d 175 Pfam PF00881 Nitroreductase family 67 153 9.4E-16 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Mlab_0992 94ca468717f9dcf4373ae424b7cf840d 175 SUPERFAMILY SSF55469 5 175 3.66E-50 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 Pfam PF00118 TCP-1/cpn60 chaperonin family 36 522 8.0E-148 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 SUPERFAMILY SSF48592 17 522 2.62E-82 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 Gene3D G3DSA:3.30.260.10 148 403 6.2E-165 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 Gene3D G3DSA:3.50.7.10 218 367 6.2E-165 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 90 109 2.2E-27 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 60 78 2.2E-27 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 2.2E-27 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 405 417 2.2E-27 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 371 393 2.2E-27 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 SUPERFAMILY SSF52029 214 376 1.15E-38 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 SUPERFAMILY SSF54849 151 403 6.71E-20 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 Gene3D G3DSA:1.10.560.10 28 519 6.2E-165 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0771 5349b66f0e105daeee510214369d4f3b 528 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 62 78 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_1500 d048b3fc554dae43fda52e0430aaedf1 149 SUPERFAMILY SSF54919 1 148 1.1E-56 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Mlab_1500 d048b3fc554dae43fda52e0430aaedf1 149 Gene3D G3DSA:3.30.70.141 1 149 1.2E-58 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Mlab_1500 d048b3fc554dae43fda52e0430aaedf1 149 Pfam PF00334 Nucleoside diphosphate kinase 2 135 2.1E-53 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Mlab_1500 d048b3fc554dae43fda52e0430aaedf1 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 2.0E-45 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Mlab_1500 d048b3fc554dae43fda52e0430aaedf1 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 2.0E-45 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Mlab_1500 d048b3fc554dae43fda52e0430aaedf1 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 2.0E-45 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Mlab_1500 d048b3fc554dae43fda52e0430aaedf1 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 2.0E-45 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Mlab_1500 d048b3fc554dae43fda52e0430aaedf1 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 2.0E-45 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Mlab_1500 d048b3fc554dae43fda52e0430aaedf1 149 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 34.047 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Mlab_1500 d048b3fc554dae43fda52e0430aaedf1 149 SMART SM00562 1 138 7.3E-76 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Mlab_0341 c43a6ce27e3763b8c41bfd6eaba1c114 293 Gene3D G3DSA:3.40.50.300 119 288 1.9E-20 T 23-10-2018 Mlab_0341 c43a6ce27e3763b8c41bfd6eaba1c114 293 Gene3D G3DSA:3.30.70.20 89 118 3.8E-6 T 23-10-2018 Mlab_0341 c43a6ce27e3763b8c41bfd6eaba1c114 293 Gene3D G3DSA:3.30.70.20 32 88 5.8E-8 T 23-10-2018 Mlab_0341 c43a6ce27e3763b8c41bfd6eaba1c114 293 Pfam PF13187 4Fe-4S dicluster domain 69 112 2.6E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0341 c43a6ce27e3763b8c41bfd6eaba1c114 293 SUPERFAMILY SSF54862 91 135 2.72E-5 T 23-10-2018 Mlab_0341 c43a6ce27e3763b8c41bfd6eaba1c114 293 SUPERFAMILY SSF52540 1 287 6.45E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0341 c43a6ce27e3763b8c41bfd6eaba1c114 293 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 264 3.2E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Mlab_1041 7b70802b406d3506c05ce16de87be979 248 ProSitePatterns PS00692 NifH/frxC family signature 2. 123 136 - T 23-10-2018 IPR030655 NifH/chlL conserved site Mlab_1041 7b70802b406d3506c05ce16de87be979 248 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 2 246 2.5E-96 T 23-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 Mlab_1041 7b70802b406d3506c05ce16de87be979 248 ProSitePatterns PS00746 NifH/frxC family signature 1. 84 96 - T 23-10-2018 IPR030655 NifH/chlL conserved site Mlab_1041 7b70802b406d3506c05ce16de87be979 248 PRINTS PR00091 Nitrogenase component II signature 7 20 5.5E-32 T 23-10-2018 Mlab_1041 7b70802b406d3506c05ce16de87be979 248 PRINTS PR00091 Nitrogenase component II signature 82 96 5.5E-32 T 23-10-2018 Mlab_1041 7b70802b406d3506c05ce16de87be979 248 PRINTS PR00091 Nitrogenase component II signature 122 137 5.5E-32 T 23-10-2018 Mlab_1041 7b70802b406d3506c05ce16de87be979 248 PRINTS PR00091 Nitrogenase component II signature 29 44 5.5E-32 T 23-10-2018 Mlab_1041 7b70802b406d3506c05ce16de87be979 248 SUPERFAMILY SSF52540 1 247 1.05E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1041 7b70802b406d3506c05ce16de87be979 248 Gene3D G3DSA:3.40.50.300 1 248 2.2E-58 T 23-10-2018 Mlab_1041 7b70802b406d3506c05ce16de87be979 248 PIRSF PIRSF000363 1 248 5.0E-100 T 23-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 Mlab_0057 60dd07467ddc25ed5a88a203eb27aed0 412 SUPERFAMILY SSF143968 272 409 2.88E-39 T 23-10-2018 Mlab_0057 60dd07467ddc25ed5a88a203eb27aed0 412 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 7 374 3.8E-91 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Mlab_0057 60dd07467ddc25ed5a88a203eb27aed0 412 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 90 398 2.6E-110 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Mlab_0057 60dd07467ddc25ed5a88a203eb27aed0 412 SUPERFAMILY SSF50475 1 269 1.29E-64 T 23-10-2018 Mlab_0057 60dd07467ddc25ed5a88a203eb27aed0 412 Gene3D G3DSA:3.40.1670.10 287 397 8.6E-34 T 23-10-2018 Mlab_1272 5bc74a02f3f51ebc1928bc434b9e356e 224 SMART SM00382 25 193 1.3E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1272 5bc74a02f3f51ebc1928bc434b9e356e 224 Gene3D G3DSA:3.40.50.300 1 223 1.1E-47 T 23-10-2018 Mlab_1272 5bc74a02f3f51ebc1928bc434b9e356e 224 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 15 221 5.5E-71 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 Mlab_1272 5bc74a02f3f51ebc1928bc434b9e356e 224 PIRSF PIRSF003336 2 224 1.1E-67 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 Mlab_1272 5bc74a02f3f51ebc1928bc434b9e356e 224 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 14 222 31.882 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 Mlab_1272 5bc74a02f3f51ebc1928bc434b9e356e 224 Pfam PF08423 Rad51 5 199 2.4E-28 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 Mlab_1272 5bc74a02f3f51ebc1928bc434b9e356e 224 SUPERFAMILY SSF52540 5 222 6.48E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1657 a3abcce87bec90274cb2fb4bcd821213 210 Pfam PF02581 Thiamine monophosphate synthase 5 187 6.1E-56 T 23-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1657 a3abcce87bec90274cb2fb4bcd821213 210 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 5 199 4.7E-57 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1657 a3abcce87bec90274cb2fb4bcd821213 210 SUPERFAMILY SSF51391 3 205 1.29E-60 T 23-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1657 a3abcce87bec90274cb2fb4bcd821213 210 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 2 205 26.608 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1657 a3abcce87bec90274cb2fb4bcd821213 210 Gene3D G3DSA:3.20.20.70 1 209 1.4E-64 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0431 c66a499d510a235fe1f62179bc4dad4a 397 Pfam PF01494 FAD binding domain 100 309 7.0E-7 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 Mlab_0431 c66a499d510a235fe1f62179bc4dad4a 397 Pfam PF12831 FAD dependent oxidoreductase 6 40 6.5E-9 T 23-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal Mlab_0431 c66a499d510a235fe1f62179bc4dad4a 397 SUPERFAMILY SSF51905 5 330 4.77E-40 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0431 c66a499d510a235fe1f62179bc4dad4a 397 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 5 307 8.6E-62 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 Mlab_0431 c66a499d510a235fe1f62179bc4dad4a 397 Gene3D G3DSA:3.50.50.60 5 347 9.8E-113 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0431 c66a499d510a235fe1f62179bc4dad4a 397 Gene3D G3DSA:3.30.9.10 70 365 9.8E-113 T 23-10-2018 Mlab_0431 c66a499d510a235fe1f62179bc4dad4a 397 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 3 394 46.934 T 23-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 Mlab_0431 c66a499d510a235fe1f62179bc4dad4a 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.8E-12 T 23-10-2018 Mlab_0431 c66a499d510a235fe1f62179bc4dad4a 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 287 1.8E-12 T 23-10-2018 Mlab_0431 c66a499d510a235fe1f62179bc4dad4a 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.8E-12 T 23-10-2018 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 Gene3D G3DSA:3.30.420.40 158 339 4.9E-141 T 23-10-2018 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 5 581 3.6E-277 T 23-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 169 182 - T 23-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 Pfam PF00012 Hsp70 protein 6 581 1.5E-241 T 23-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 SUPERFAMILY SSF53067 6 162 1.78E-57 T 23-10-2018 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 Gene3D G3DSA:3.30.420.40 7 350 4.9E-141 T 23-10-2018 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 Gene3D G3DSA:1.20.1270.10 480 588 1.1E-22 T 23-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 SUPERFAMILY SSF100934 507 584 7.65E-10 T 23-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 PRINTS PR00301 70kDa heat shock protein signature 361 380 2.4E-76 T 23-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 PRINTS PR00301 70kDa heat shock protein signature 33 45 2.4E-76 T 23-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 PRINTS PR00301 70kDa heat shock protein signature 175 185 2.4E-76 T 23-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 PRINTS PR00301 70kDa heat shock protein signature 338 358 2.4E-76 T 23-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 PRINTS PR00301 70kDa heat shock protein signature 5 18 2.4E-76 T 23-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 PRINTS PR00301 70kDa heat shock protein signature 56 64 2.4E-76 T 23-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 PRINTS PR00301 70kDa heat shock protein signature 116 136 2.4E-76 T 23-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 PRINTS PR00301 70kDa heat shock protein signature 442 458 2.4E-76 T 23-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 PRINTS PR00301 70kDa heat shock protein signature 307 323 2.4E-76 T 23-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 SUPERFAMILY SSF100920 357 513 1.06E-59 T 23-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 23-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 3 619 36.115 T 23-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 9 16 - T 23-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 Gene3D G3DSA:3.90.640.10 202 289 4.9E-141 T 23-10-2018 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 Gene3D G3DSA:2.60.34.10 351 478 1.3E-56 T 23-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Mlab_0943 cca31ea2536b3f50a66a2d07e35cbb14 621 SUPERFAMILY SSF53067 166 355 7.5E-66 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 Gene3D G3DSA:3.30.70.100 1 65 3.2E-18 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 Gene3D G3DSA:3.40.50.1000 408 669 3.0E-86 T 23-10-2018 IPR023214 HAD superfamily Mlab_1233 91a80264120d6357fa600dafc9a16343 810 Gene3D G3DSA:3.40.1110.10 438 549 3.0E-86 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00943 Copper-transporting ATPase signature 410 425 4.8E-14 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00943 Copper-transporting ATPase signature 350 364 4.8E-14 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00943 Copper-transporting ATPase signature 218 236 4.8E-14 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00943 Copper-transporting ATPase signature 651 665 4.8E-14 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00943 Copper-transporting ATPase signature 137 156 4.8E-14 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00943 Copper-transporting ATPase signature 594 611 4.8E-14 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 ProSitePatterns PS01047 Heavy-metal-associated domain. 748 777 - T 23-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 152 726 6.8E-178 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 178 727 9.7E-169 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 743 806 7.8E-11 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 2 64 9.7E-11 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 278 292 2.8E-27 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 553 2.8E-27 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 427 441 2.8E-27 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 564 574 2.8E-27 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 617 636 2.8E-27 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 640 652 2.8E-27 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 Pfam PF00122 E1-E2 ATPase 229 405 4.1E-50 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 429 435 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 200 697 5.2E-89 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 183 726 8.2E-117 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 SUPERFAMILY SSF56784 425 724 1.92E-56 T 23-10-2018 IPR036412 HAD-like superfamily Mlab_1233 91a80264120d6357fa600dafc9a16343 810 Gene3D G3DSA:3.30.70.100 742 807 2.2E-16 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 SUPERFAMILY SSF81653 231 327 1.18E-24 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 SUPERFAMILY SSF55008 738 807 1.7E-16 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 Pfam PF00702 haloacid dehalogenase-like hydrolase 424 631 3.2E-35 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 Pfam PF00403 Heavy-metal-associated domain 746 805 9.8E-15 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 Pfam PF00403 Heavy-metal-associated domain 4 63 3.8E-14 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 Gene3D G3DSA:2.70.150.20 221 332 3.2E-35 T 23-10-2018 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 SUPERFAMILY SSF81665 185 713 1.05E-15 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Mlab_1233 91a80264120d6357fa600dafc9a16343 810 SUPERFAMILY SSF55008 1 69 6.15E-17 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 598 710 1.1E-12 T 23-10-2018 IPR000014 PAS domain Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 188 312 2.6E-17 T 23-10-2018 IPR000014 PAS domain Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 SUPERFAMILY SSF55785 588 710 3.21E-19 T 23-10-2018 IPR035965 PAS domain superfamily Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 Gene3D G3DSA:3.30.450.20 611 714 2.2E-15 T 23-10-2018 Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 SUPERFAMILY SSF55781 446 609 1.67E-5 T 23-10-2018 Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 49 9.1E-7 T 23-10-2018 Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 SUPERFAMILY SSF55785 72 179 4.71E-11 T 23-10-2018 IPR035965 PAS domain superfamily Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 Gene3D G3DSA:3.30.450.20 308 432 1.7E-9 T 23-10-2018 Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 SMART SM00091 320 387 3.6 T 23-10-2018 IPR000014 PAS domain Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 SMART SM00091 68 135 8.5 T 23-10-2018 IPR000014 PAS domain Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 SMART SM00091 192 258 3.0E-12 T 23-10-2018 IPR000014 PAS domain Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 SMART SM00091 600 667 5.8E-7 T 23-10-2018 IPR000014 PAS domain Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 SUPERFAMILY SSF55785 177 306 2.09E-23 T 23-10-2018 IPR035965 PAS domain superfamily Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 SUPERFAMILY SSF55785 305 432 1.48E-9 T 23-10-2018 IPR035965 PAS domain superfamily Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 Gene3D G3DSA:1.10.10.10 9 69 9.8E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 Gene3D G3DSA:3.30.450.20 75 191 1.7E-13 T 23-10-2018 Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 Gene3D G3DSA:3.30.450.20 192 307 6.9E-22 T 23-10-2018 Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 Pfam PF08447 PAS fold 630 709 3.6E-7 T 23-10-2018 IPR013655 PAS fold-3 GO:0005515 Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 SUPERFAMILY SSF46785 10 66 1.39E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 Pfam PF08448 PAS fold 75 180 4.0E-10 T 23-10-2018 IPR013656 PAS fold-4 Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 Pfam PF08448 PAS fold 327 434 4.0E-8 T 23-10-2018 IPR013656 PAS fold-4 Mlab_0201 9410822a0f37a3fd533a3cae7370fd3e 715 Pfam PF00989 PAS fold 193 305 2.7E-11 T 23-10-2018 IPR013767 PAS fold GO:0006355 Mlab_1226 30d2392dd168b45bee789d97e67e00ac 64 Gene3D G3DSA:1.10.60.20 1 60 1.3E-20 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1226 30d2392dd168b45bee789d97e67e00ac 64 Pfam PF00833 Ribosomal S17 7 57 3.2E-10 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1226 30d2392dd168b45bee789d97e67e00ac 64 ProSitePatterns PS00712 Ribosomal protein S17e signature. 40 55 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1226 30d2392dd168b45bee789d97e67e00ac 64 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 62 18.117 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1226 30d2392dd168b45bee789d97e67e00ac 64 SUPERFAMILY SSF116820 1 58 1.44E-18 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0116 52b85719dea1908f0e325d43b8fe0138 505 Gene3D G3DSA:1.10.10.350 411 502 7.0E-22 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Mlab_0116 52b85719dea1908f0e325d43b8fe0138 505 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 9 499 1.6E-154 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 Mlab_0116 52b85719dea1908f0e325d43b8fe0138 505 Pfam PF01921 tRNA synthetases class I (K) 10 334 2.4E-125 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 Mlab_0116 52b85719dea1908f0e325d43b8fe0138 505 Gene3D G3DSA:1.10.10.770 319 410 4.5E-12 T 23-10-2018 Mlab_0116 52b85719dea1908f0e325d43b8fe0138 505 SUPERFAMILY SSF48163 341 500 8.76E-29 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Mlab_0116 52b85719dea1908f0e325d43b8fe0138 505 Gene3D G3DSA:1.10.10.860 272 318 4.3E-11 T 23-10-2018 Mlab_0116 52b85719dea1908f0e325d43b8fe0138 505 Gene3D G3DSA:2.30.30.300 169 214 1.7E-96 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 Mlab_0116 52b85719dea1908f0e325d43b8fe0138 505 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 9 504 35.146 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 Mlab_0116 52b85719dea1908f0e325d43b8fe0138 505 Gene3D G3DSA:3.40.50.620 11 271 1.7E-96 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0116 52b85719dea1908f0e325d43b8fe0138 505 SUPERFAMILY SSF52374 21 319 7.7E-61 T 23-10-2018 Mlab_0116 52b85719dea1908f0e325d43b8fe0138 505 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 33 42 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0846 e9d045ec3c7d7ab0d59f2e896885904b 438 Gene3D G3DSA:3.30.1330.10 70 222 1.2E-17 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0846 e9d045ec3c7d7ab0d59f2e896885904b 438 SUPERFAMILY SSF55326 61 218 2.54E-22 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0846 e9d045ec3c7d7ab0d59f2e896885904b 438 Pfam PF00586 AIR synthase related protein, N-terminal domain 119 218 1.1E-7 T 23-10-2018 IPR016188 PurM-like, N-terminal domain Mlab_0846 e9d045ec3c7d7ab0d59f2e896885904b 438 SUPERFAMILY SSF56042 226 377 3.74E-23 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0846 e9d045ec3c7d7ab0d59f2e896885904b 438 Pfam PF02769 AIR synthase related protein, C-terminal domain 230 378 1.8E-14 T 23-10-2018 IPR010918 PurM-like, C-terminal domain Mlab_0846 e9d045ec3c7d7ab0d59f2e896885904b 438 PIRSF PIRSF006346 1 438 4.8E-178 T 23-10-2018 IPR009186 Predicted nickel metalloenzyme maturation factor, AIR synthase-related Mlab_0846 e9d045ec3c7d7ab0d59f2e896885904b 438 Gene3D G3DSA:3.90.650.10 225 394 3.1E-19 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_1388 3d570c9f25ab9c4daace0eb8daf159e6 419 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 16 236 5.5E-26 T 23-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit Mlab_0068 98c0ab60143ea37787cacd3a6b245709 394 Gene3D G3DSA:2.60.40.1120 195 272 5.0E-5 T 23-10-2018 Mlab_0068 98c0ab60143ea37787cacd3a6b245709 394 Gene3D G3DSA:2.60.40.1120 113 187 3.6E-5 T 23-10-2018 Mlab_0068 98c0ab60143ea37787cacd3a6b245709 394 SUPERFAMILY SSF49478 38 97 2.51E-5 T 23-10-2018 Mlab_0068 98c0ab60143ea37787cacd3a6b245709 394 SUPERFAMILY SSF49464 278 345 1.26E-6 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily Mlab_0068 98c0ab60143ea37787cacd3a6b245709 394 Gene3D G3DSA:2.60.40.1120 273 345 4.6E-6 T 23-10-2018 Mlab_0068 98c0ab60143ea37787cacd3a6b245709 394 Gene3D G3DSA:2.60.40.1120 32 105 1.9E-5 T 23-10-2018 Mlab_0068 98c0ab60143ea37787cacd3a6b245709 394 SUPERFAMILY SSF49464 116 187 1.43E-5 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily Mlab_0068 98c0ab60143ea37787cacd3a6b245709 394 SUPERFAMILY SSF49464 196 258 2.0E-5 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily Mlab_1395 de0e2188965091793acbada6388d37fd 192 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 185 1.8E-25 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Mlab_1395 de0e2188965091793acbada6388d37fd 192 SUPERFAMILY SSF51366 1 187 1.4E-38 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_1395 de0e2188965091793acbada6388d37fd 192 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 190 27.539 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Mlab_1395 de0e2188965091793acbada6388d37fd 192 Gene3D G3DSA:3.20.20.70 1 189 1.8E-42 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1561 becc92b987298af56d62a1172837f28c 568 SUPERFAMILY SSF55088 5 279 1.18E-143 T 23-10-2018 IPR009024 Methyl-coenzyme M reductase, ferredoxin-like fold GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1561 becc92b987298af56d62a1172837f28c 568 Gene3D G3DSA:3.90.390.10 4 111 1.1E-41 T 23-10-2018 IPR015811 Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 1 GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1561 becc92b987298af56d62a1172837f28c 568 Gene3D G3DSA:1.20.840.10 287 554 1.1E-138 T 23-10-2018 IPR008924 Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1561 becc92b987298af56d62a1172837f28c 568 Gene3D G3DSA:3.30.70.470 112 286 1.4E-90 T 23-10-2018 IPR015823 Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 2 GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1561 becc92b987298af56d62a1172837f28c 568 TIGRFAM TIGR03256 met_CoM_red_alp: methyl-coenzyme M reductase, alpha subunit 8 567 3.1E-288 T 23-10-2018 IPR016212 Methyl coenzyme M reductase, alpha subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1561 becc92b987298af56d62a1172837f28c 568 SUPERFAMILY SSF48081 280 567 4.97E-144 T 23-10-2018 IPR008924 Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1561 becc92b987298af56d62a1172837f28c 568 Pfam PF02745 Methyl-coenzyme M reductase alpha subunit, N-terminal domain 8 278 1.2E-153 T 23-10-2018 IPR003183 Methyl-coenzyme M reductase, alpha subunit, N-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1561 becc92b987298af56d62a1172837f28c 568 Pfam PF02249 Methyl-coenzyme M reductase alpha subunit, C-terminal domain 326 459 3.0E-70 T 23-10-2018 IPR009047 Methyl-coenzyme M reductase, alpha subunit, C-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1561 becc92b987298af56d62a1172837f28c 568 PIRSF PIRSF000262 3 568 6.7E-296 T 23-10-2018 IPR016212 Methyl coenzyme M reductase, alpha subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_0922 af2622c12e9ad826c60db96c9220e184 377 Pfam PF02441 Flavoprotein 8 168 2.8E-33 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 Mlab_0922 af2622c12e9ad826c60db96c9220e184 377 Gene3D G3DSA:3.40.50.1950 3 173 1.3E-42 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Mlab_0922 af2622c12e9ad826c60db96c9220e184 377 Gene3D G3DSA:3.40.50.10300 174 377 7.1E-43 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Mlab_0922 af2622c12e9ad826c60db96c9220e184 377 SUPERFAMILY SSF52507 1 171 4.06E-41 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Mlab_0922 af2622c12e9ad826c60db96c9220e184 377 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 376 3.6E-91 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 Mlab_0922 af2622c12e9ad826c60db96c9220e184 377 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 181 348 3.8E-35 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Mlab_0922 af2622c12e9ad826c60db96c9220e184 377 SUPERFAMILY SSF102645 179 376 2.49E-40 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 SUPERFAMILY SSF51735 180 415 7.14E-67 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 213 233 7.3E-26 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 342 353 7.3E-26 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 7.3E-26 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 171 193 7.3E-26 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 180 414 4.7E-62 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 Gene3D G3DSA:3.40.50.720 180 416 1.7E-76 T 23-10-2018 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 PIRSF PIRSF000185 1 416 4.0E-153 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 Gene3D G3DSA:3.40.50.10860 36 179 1.3E-63 T 23-10-2018 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 SMART SM00839 182 414 1.3E-68 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 SUPERFAMILY SSF53223 4 182 6.4E-68 T 23-10-2018 Mlab_0706 8e05c3eb64f9302e2c3d19d369d4fb5f 416 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 2.8E-54 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Mlab_0896 71bde7ab0be821eff4cac1f10735892c 393 Gene3D G3DSA:3.40.50.2000 173 367 1.6E-50 T 23-10-2018 Mlab_0896 71bde7ab0be821eff4cac1f10735892c 393 SUPERFAMILY SSF53756 10 383 9.42E-58 T 23-10-2018 Mlab_0896 71bde7ab0be821eff4cac1f10735892c 393 Pfam PF13439 Glycosyltransferase Family 4 14 175 1.3E-8 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Mlab_0896 71bde7ab0be821eff4cac1f10735892c 393 Pfam PF00534 Glycosyl transferases group 1 187 317 5.3E-28 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 Mlab_0896 71bde7ab0be821eff4cac1f10735892c 393 Gene3D G3DSA:3.40.50.2000 14 376 1.6E-50 T 23-10-2018 Mlab_1524 3c1cd7136e9826bae170316b6d7fc1f2 152 PIRSF PIRSF001467 1 152 1.2E-49 T 23-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 Mlab_1524 3c1cd7136e9826bae170316b6d7fc1f2 152 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 39 56 - T 23-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 Mlab_1524 3c1cd7136e9826bae170316b6d7fc1f2 152 Gene3D G3DSA:2.40.100.10 1 152 1.8E-60 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily Mlab_1524 3c1cd7136e9826bae170316b6d7fc1f2 152 SUPERFAMILY SSF50891 4 152 1.9E-58 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily Mlab_1524 3c1cd7136e9826bae170316b6d7fc1f2 152 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 44 56 1.8E-25 T 23-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Mlab_1524 3c1cd7136e9826bae170316b6d7fc1f2 152 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 83 98 1.8E-25 T 23-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Mlab_1524 3c1cd7136e9826bae170316b6d7fc1f2 152 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 98 110 1.8E-25 T 23-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Mlab_1524 3c1cd7136e9826bae170316b6d7fc1f2 152 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 18 33 1.8E-25 T 23-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Mlab_1524 3c1cd7136e9826bae170316b6d7fc1f2 152 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 111 126 1.8E-25 T 23-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Mlab_1524 3c1cd7136e9826bae170316b6d7fc1f2 152 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 6 150 1.3E-49 T 23-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Mlab_1299 b92534dc579dbbdbfe792c2869caa188 257 SUPERFAMILY SSF50249 9 86 1.72E-17 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_1299 b92534dc579dbbdbfe792c2869caa188 257 SMART SM00316 8 81 7.9E-18 T 23-10-2018 IPR022967 RNA-binding domain, S1 Mlab_1299 b92534dc579dbbdbfe792c2869caa188 257 Gene3D G3DSA:1.10.150.190 83 168 5.4E-21 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 Mlab_1299 b92534dc579dbbdbfe792c2869caa188 257 SUPERFAMILY SSF116742 83 169 2.94E-20 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 Mlab_1299 b92534dc579dbbdbfe792c2869caa188 257 SUPERFAMILY SSF110993 170 252 2.35E-21 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 Mlab_1299 b92534dc579dbbdbfe792c2869caa188 257 Pfam PF00575 S1 RNA binding domain 9 81 4.1E-11 T 23-10-2018 IPR003029 S1 domain GO:0003676 Mlab_1299 b92534dc579dbbdbfe792c2869caa188 257 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 117 225 1.4E-21 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 Mlab_1299 b92534dc579dbbdbfe792c2869caa188 257 Gene3D G3DSA:3.30.70.1130 169 254 1.9E-26 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 Mlab_1299 b92534dc579dbbdbfe792c2869caa188 257 Gene3D G3DSA:2.40.50.140 1 82 7.4E-29 T 23-10-2018 Mlab_1499 89f5348c3c0b2ea108f3480e11a083bf 63 SMART SM00746 7 45 7.0E-13 T 23-10-2018 IPR011017 TRASH domain Mlab_1499 89f5348c3c0b2ea108f3480e11a083bf 63 SUPERFAMILY SSF57716 6 56 9.98E-18 T 23-10-2018 Mlab_1499 89f5348c3c0b2ea108f3480e11a083bf 63 Pfam PF01246 Ribosomal protein L24e 4 63 9.2E-25 T 23-10-2018 IPR000988 Ribosomal protein L24e-related Mlab_1499 89f5348c3c0b2ea108f3480e11a083bf 63 Gene3D G3DSA:2.30.170.20 3 63 1.1E-27 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily Mlab_1499 89f5348c3c0b2ea108f3480e11a083bf 63 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 25.805 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1499 89f5348c3c0b2ea108f3480e11a083bf 63 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site Mlab_1081 64fac011c110233f07eb83966d1511c9 220 Pfam PF02570 Precorrin-8X methylmutase 29 214 1.2E-55 T 23-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 Mlab_1081 64fac011c110233f07eb83966d1511c9 220 SUPERFAMILY SSF63965 29 216 1.7E-53 T 23-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 Mlab_1081 64fac011c110233f07eb83966d1511c9 220 Gene3D G3DSA:3.40.50.10230 23 220 9.7E-53 T 23-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 Mlab_0140 e2962be937d41c34a428d375abc047c8 542 PIRSF PIRSF000171 3 537 7.6E-45 T 23-10-2018 Mlab_0140 e2962be937d41c34a428d375abc047c8 542 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 9.9E-6 T 23-10-2018 Mlab_0140 e2962be937d41c34a428d375abc047c8 542 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 363 370 9.9E-6 T 23-10-2018 Mlab_0140 e2962be937d41c34a428d375abc047c8 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.6E-9 T 23-10-2018 Mlab_0140 e2962be937d41c34a428d375abc047c8 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 348 370 1.6E-9 T 23-10-2018 Mlab_0140 e2962be937d41c34a428d375abc047c8 542 Gene3D G3DSA:3.90.700.10 236 351 1.2E-143 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Mlab_0140 e2962be937d41c34a428d375abc047c8 542 SUPERFAMILY SSF51905 5 400 1.98E-63 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0140 e2962be937d41c34a428d375abc047c8 542 Pfam PF00890 FAD binding domain 11 384 7.4E-93 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 Mlab_0140 e2962be937d41c34a428d375abc047c8 542 Gene3D G3DSA:3.50.50.60 11 396 1.2E-143 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0140 e2962be937d41c34a428d375abc047c8 542 SUPERFAMILY SSF56425 226 345 4.78E-36 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Mlab_0140 e2962be937d41c34a428d375abc047c8 542 Pfam PF02910 Fumarate reductase flavoprotein C-term 434 514 3.9E-14 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Mlab_0140 e2962be937d41c34a428d375abc047c8 542 Gene3D G3DSA:1.20.58.100 407 513 8.8E-21 T 23-10-2018 Mlab_0140 e2962be937d41c34a428d375abc047c8 542 SUPERFAMILY SSF46977 426 511 7.98E-22 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 Pfam PF00448 SRP54-type protein, GTPase domain 98 290 8.9E-68 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 SMART SM00382 96 295 7.2E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 Gene3D G3DSA:1.10.260.30 302 444 4.8E-39 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 SUPERFAMILY SSF47446 292 421 3.66E-37 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 Pfam PF02978 Signal peptide binding domain 319 417 5.6E-31 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 SUPERFAMILY SSF47364 2 91 3.79E-22 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 SMART SM00963 2 87 1.6E-22 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.8E-17 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 SMART SM00962 97 290 1.5E-92 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 SUPERFAMILY SSF52540 96 292 4.13E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 Gene3D G3DSA:1.20.120.140 6 300 5.2E-106 T 23-10-2018 Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 Gene3D G3DSA:3.40.50.300 91 279 5.2E-106 T 23-10-2018 Mlab_1474 8ac3739ee97842ba95e33d5959f44a23 446 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 444 35.48 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 3.3E-6 T 23-10-2018 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 3.3E-6 T 23-10-2018 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 9.0E-14 T 23-10-2018 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 9.0E-14 T 23-10-2018 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 9.0E-14 T 23-10-2018 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 Gene3D G3DSA:3.40.50.880 1 189 5.7E-63 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 SUPERFAMILY SSF52317 1 187 2.21E-54 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 187 3.7E-60 T 23-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 Pfam PF00117 Glutamine amidotransferase class-I 4 186 7.4E-52 T 23-10-2018 IPR017926 Glutamine amidotransferase Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 PRINTS PR00097 Anthranilate synthase component II signature 3 17 4.2E-32 T 23-10-2018 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 PRINTS PR00097 Anthranilate synthase component II signature 47 56 4.2E-32 T 23-10-2018 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 PRINTS PR00097 Anthranilate synthase component II signature 165 178 4.2E-32 T 23-10-2018 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 PRINTS PR00097 Anthranilate synthase component II signature 119 131 4.2E-32 T 23-10-2018 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 PRINTS PR00097 Anthranilate synthase component II signature 99 107 4.2E-32 T 23-10-2018 Mlab_1398 0c8e66699f46c050ed90b0c81a239d0f 192 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.2E-32 T 23-10-2018 Mlab_0811 2cbcccf5500cfff5d40613f322e3b205 401 Pfam PF01553 Acyltransferase 36 143 2.0E-9 T 23-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Mlab_0811 2cbcccf5500cfff5d40613f322e3b205 401 SMART SM00563 42 159 4.6E-8 T 23-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Mlab_0811 2cbcccf5500cfff5d40613f322e3b205 401 SUPERFAMILY SSF69593 34 144 3.27E-13 T 23-10-2018 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 1.9E-25 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 289 1.9E-25 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 254 263 1.9E-25 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 130 141 1.9E-25 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 SUPERFAMILY SSF53671 2 302 1.44E-108 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 149 299 1.7E-53 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 302 81.442 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 Gene3D G3DSA:3.40.50.1370 133 297 1.2E-120 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 301 3.8E-129 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 Gene3D G3DSA:3.40.50.1370 3 132 1.2E-120 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 143 7.2E-51 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 280 291 1.5E-29 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 119 133 1.5E-29 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 79 92 1.5E-29 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 46 60 1.5E-29 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Mlab_0315 e53b7dec0645d735c6657964702f47fd 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 218 228 1.5E-29 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 Gene3D G3DSA:3.40.50.720 93 282 6.4E-122 T 23-10-2018 Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 SUPERFAMILY SSF52283 3 135 5.48E-37 T 23-10-2018 Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 SUPERFAMILY SSF55021 451 525 1.12E-14 T 23-10-2018 Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 312 5.2E-37 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 4 527 5.3E-196 T 23-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 SUPERFAMILY SSF143548 318 449 1.07E-31 T 23-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 Pfam PF01842 ACT domain 454 514 1.7E-7 T 23-10-2018 IPR002912 ACT domain Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 191 213 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 SUPERFAMILY SSF51735 101 281 4.26E-58 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 280 2.3E-63 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 Gene3D G3DSA:3.30.70.260 454 527 6.3E-18 T 23-10-2018 Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 Gene3D G3DSA:3.30.1330.90 317 453 7.9E-33 T 23-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 143 170 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Mlab_1543 69305c61fb8259bba66bcab254df5f50 527 Gene3D G3DSA:3.40.50.720 5 291 6.4E-122 T 23-10-2018 Mlab_1297 f41e2f3c24719c528a3a3a9d6e449288 252 Gene3D G3DSA:3.40.50.10900 14 249 1.3E-48 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily Mlab_1297 f41e2f3c24719c528a3a3a9d6e449288 252 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 4 252 9.4E-65 T 23-10-2018 IPR004426 Conserved hypothetical protein CHP00062 Mlab_1297 f41e2f3c24719c528a3a3a9d6e449288 252 Pfam PF09754 PAC2 family 22 235 1.7E-40 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 Mlab_1297 f41e2f3c24719c528a3a3a9d6e449288 252 SUPERFAMILY SSF159659 7 241 2.75E-36 T 23-10-2018 Mlab_1510 420e3f9ce24b16e34c78561169a097f0 522 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 44 499 4.2E-79 T 23-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 Mlab_1510 420e3f9ce24b16e34c78561169a097f0 522 Pfam PF00939 Sodium:sulfate symporter transmembrane region 22 498 1.0E-83 T 23-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 Mlab_1369 95e48909a26005b1cc286bf0f313f5cb 418 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 222 1.7E-9 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Mlab_1369 95e48909a26005b1cc286bf0f313f5cb 418 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 78 94 1.7E-9 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Mlab_1369 95e48909a26005b1cc286bf0f313f5cb 418 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 309 319 1.7E-9 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Mlab_1369 95e48909a26005b1cc286bf0f313f5cb 418 SUPERFAMILY SSF52374 5 412 3.51E-62 T 23-10-2018 Mlab_1369 95e48909a26005b1cc286bf0f313f5cb 418 Gene3D G3DSA:1.10.240.10 310 418 5.2E-37 T 23-10-2018 Mlab_1369 95e48909a26005b1cc286bf0f313f5cb 418 Pfam PF00579 tRNA synthetases class I (W and Y) 63 224 2.9E-15 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1369 95e48909a26005b1cc286bf0f313f5cb 418 Pfam PF00579 tRNA synthetases class I (W and Y) 277 402 5.0E-15 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1369 95e48909a26005b1cc286bf0f313f5cb 418 Gene3D G3DSA:3.40.50.620 1 231 3.5E-45 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_1414 806db3a1ab36aebe392c36f8f6efabad 294 TIGRFAM TIGR03281 methan_mark_12: putative methanogenesis marker protein 12 2 289 3.8E-101 T 23-10-2018 IPR016735 Uncharacterised protein family UPF0285, methanogenesis Mlab_1414 806db3a1ab36aebe392c36f8f6efabad 294 Hamap MF_01087 UPF0285 protein . 1 294 146.368 T 23-10-2018 IPR016735 Uncharacterised protein family UPF0285, methanogenesis Mlab_0551 ae3a182da86d09126f12c868e0bf5fca 420 TIGRFAM TIGR03286 methan_mark_15: putative methanogenesis marker protein 15 8 412 2.3E-210 T 23-10-2018 IPR017676 Putative methanogenesis marker protein 15 Mlab_0551 ae3a182da86d09126f12c868e0bf5fca 420 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 153 408 2.7E-93 T 23-10-2018 IPR008275 CoA enzyme activase Mlab_0551 ae3a182da86d09126f12c868e0bf5fca 420 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 155 408 1.6E-55 T 23-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Mlab_0551 ae3a182da86d09126f12c868e0bf5fca 420 Gene3D G3DSA:3.30.420.40 154 408 2.7E-56 T 23-10-2018 Mlab_0551 ae3a182da86d09126f12c868e0bf5fca 420 Gene3D G3DSA:3.30.420.40 250 392 2.7E-56 T 23-10-2018 Mlab_0551 ae3a182da86d09126f12c868e0bf5fca 420 SUPERFAMILY SSF53067 154 408 4.72E-33 T 23-10-2018 Mlab_1113 d29c53efccae45185fb5699dde6ff920 307 Pfam PF16916 Dimerisation domain of Zinc Transporter 212 290 1.4E-22 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain Mlab_1113 d29c53efccae45185fb5699dde6ff920 307 Pfam PF01545 Cation efflux family 12 208 8.2E-43 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Mlab_1113 d29c53efccae45185fb5699dde6ff920 307 Gene3D G3DSA:1.20.1510.10 7 207 3.6E-55 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Mlab_1113 d29c53efccae45185fb5699dde6ff920 307 SUPERFAMILY SSF161111 7 209 1.44E-52 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Mlab_1113 d29c53efccae45185fb5699dde6ff920 307 Gene3D G3DSA:3.30.70.1350 208 296 3.1E-26 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Mlab_1113 d29c53efccae45185fb5699dde6ff920 307 SUPERFAMILY SSF160240 211 291 5.75E-21 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Mlab_1113 d29c53efccae45185fb5699dde6ff920 307 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 291 3.4E-69 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Mlab_0426 4a9a013f3f971ba7aad0beea5f43ae86 151 Gene3D G3DSA:2.40.50.140 93 150 3.6E-13 T 23-10-2018 Mlab_0426 4a9a013f3f971ba7aad0beea5f43ae86 151 SUPERFAMILY SSF50104 28 100 8.02E-19 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily Mlab_0426 4a9a013f3f971ba7aad0beea5f43ae86 151 PIRSF PIRSF003025 15 150 5.0E-38 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 Mlab_0426 4a9a013f3f971ba7aad0beea5f43ae86 151 SMART SM01376 92 149 0.0076 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 Mlab_0426 4a9a013f3f971ba7aad0beea5f43ae86 151 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 25 151 29.599 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal Mlab_0426 4a9a013f3f971ba7aad0beea5f43ae86 151 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 25 149 2.4E-44 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 Mlab_0426 4a9a013f3f971ba7aad0beea5f43ae86 151 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 57 64 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 Mlab_0426 4a9a013f3f971ba7aad0beea5f43ae86 151 SUPERFAMILY SSF50249 92 148 1.46E-7 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0426 4a9a013f3f971ba7aad0beea5f43ae86 151 Gene3D G3DSA:2.30.30.30 23 91 4.5E-26 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 Mlab_1570 598723864a6e5faf62c539b8f7cd93d7 192 Gene3D G3DSA:2.40.50.140 12 83 4.4E-23 T 23-10-2018 Mlab_1570 598723864a6e5faf62c539b8f7cd93d7 192 Pfam PF04919 Protein of unknown function (DUF655) 12 190 2.6E-64 T 23-10-2018 IPR007003 Protein of unknown function DUF655 Mlab_1570 598723864a6e5faf62c539b8f7cd93d7 192 Gene3D G3DSA:1.10.150.280 84 181 2.2E-35 T 23-10-2018 Mlab_1570 598723864a6e5faf62c539b8f7cd93d7 192 SUPERFAMILY SSF160975 14 191 3.01E-80 T 23-10-2018 Mlab_1636 741d3d81ccb96c77605bd47307baa788 200 Pfam PF01269 Fibrillarin 16 198 1.2E-57 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 Mlab_1636 741d3d81ccb96c77605bd47307baa788 200 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 1 200 34.862 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 Mlab_1636 741d3d81ccb96c77605bd47307baa788 200 SMART SM01206 2 199 2.9E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 Mlab_1636 741d3d81ccb96c77605bd47307baa788 200 PRINTS PR00052 Fibrillarin signature 178 199 8.1E-23 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 Mlab_1636 741d3d81ccb96c77605bd47307baa788 200 PRINTS PR00052 Fibrillarin signature 24 43 8.1E-23 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 Mlab_1636 741d3d81ccb96c77605bd47307baa788 200 PRINTS PR00052 Fibrillarin signature 97 126 8.1E-23 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 Mlab_1636 741d3d81ccb96c77605bd47307baa788 200 PRINTS PR00052 Fibrillarin signature 72 89 8.1E-23 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 Mlab_1636 741d3d81ccb96c77605bd47307baa788 200 SUPERFAMILY SSF53335 16 199 2.09E-32 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1636 741d3d81ccb96c77605bd47307baa788 200 Gene3D G3DSA:3.40.50.150 29 199 5.2E-54 T 23-10-2018 Mlab_1095 5eef26a0cbbfefefbf250e8f350e9cf5 330 Gene3D G3DSA:3.40.50.1980 24 183 5.5E-13 T 23-10-2018 Mlab_1095 5eef26a0cbbfefefbf250e8f350e9cf5 330 SUPERFAMILY SSF53807 21 302 1.72E-22 T 23-10-2018 Mlab_1095 5eef26a0cbbfefefbf250e8f350e9cf5 330 Pfam PF01297 Zinc-uptake complex component A periplasmic 27 224 2.6E-13 T 23-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 Mlab_0504 6fe822d9c6d5f3041077a4386fdda02a 371 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 106 4.7E-7 T 23-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Mlab_0504 6fe822d9c6d5f3041077a4386fdda02a 371 Gene3D G3DSA:3.40.50.970 184 343 3.2E-14 T 23-10-2018 Mlab_0504 6fe822d9c6d5f3041077a4386fdda02a 371 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 243 262 - T 23-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Mlab_0504 6fe822d9c6d5f3041077a4386fdda02a 371 SUPERFAMILY SSF52518 187 347 8.25E-18 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_0504 6fe822d9c6d5f3041077a4386fdda02a 371 TIGRFAM TIGR03846 sulfopy_beta: sulfopyruvate decarboxylase, beta subunit 191 365 2.2E-67 T 23-10-2018 IPR022494 Sulfopyruvate decarboxylase, beta subunit GO:0003824|GO:0030976 KEGG: 00680+4.1.1.79|MetaCyc: PWY-6637|MetaCyc: PWY-6643 Mlab_0504 6fe822d9c6d5f3041077a4386fdda02a 371 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 236 333 2.7E-8 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Mlab_0504 6fe822d9c6d5f3041077a4386fdda02a 371 TIGRFAM TIGR03845 sulfopyru_alph: sulfopyruvate decarboxylase, alpha subunit 3 159 4.8E-64 T 23-10-2018 IPR022502 Sulfopyruvate decarboxylase, alpha subunit GO:0030976|GO:0050545 KEGG: 00680+4.1.1.79|MetaCyc: PWY-6637|MetaCyc: PWY-6643 Mlab_0504 6fe822d9c6d5f3041077a4386fdda02a 371 SUPERFAMILY SSF52518 4 155 2.04E-13 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_1525 4e1549ffe5ef628ffd5945ed8568c6a2 381 Pfam PF13186 Iron-sulfur cluster-binding domain 244 305 5.9E-6 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain Mlab_1525 4e1549ffe5ef628ffd5945ed8568c6a2 381 TIGRFAM TIGR04083 rSAM_pep_methan: putative peptide-modifying radical SAM enzyme, Mhun_1560 family 6 377 1.2E-205 T 23-10-2018 IPR024018 Conserved hypothetical protein CHP04083, radical SAM Mlab_1525 4e1549ffe5ef628ffd5945ed8568c6a2 381 Gene3D G3DSA:3.20.20.70 2 355 4.6E-72 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1525 4e1549ffe5ef628ffd5945ed8568c6a2 381 Pfam PF04055 Radical SAM superfamily 9 152 2.4E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_1525 4e1549ffe5ef628ffd5945ed8568c6a2 381 SUPERFAMILY SSF102114 4 315 3.4E-40 T 23-10-2018 Mlab_1525 4e1549ffe5ef628ffd5945ed8568c6a2 381 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 244 334 3.2E-17 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain Mlab_0105 12502a965798e1bbbb8a7e055d850642 190 Pfam PF13207 AAA domain 9 146 3.8E-34 T 23-10-2018 Mlab_0105 12502a965798e1bbbb8a7e055d850642 190 Hamap MF_00234 Adenylate kinase [adkA]. 4 190 46.086 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 Mlab_0105 12502a965798e1bbbb8a7e055d850642 190 SUPERFAMILY SSF52540 3 189 2.68E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0105 12502a965798e1bbbb8a7e055d850642 190 Gene3D G3DSA:3.40.50.300 1 190 4.4E-56 T 23-10-2018 Mlab_0400 51137ae253f95e7025771eea849ac48e 377 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 12 358 6.9E-66 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea Mlab_0400 51137ae253f95e7025771eea849ac48e 377 Gene3D G3DSA:1.10.8.60 12 278 1.6E-66 T 23-10-2018 Mlab_0400 51137ae253f95e7025771eea849ac48e 377 SUPERFAMILY SSF52540 12 277 1.55E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0400 51137ae253f95e7025771eea849ac48e 377 Gene3D G3DSA:3.40.50.300 28 205 1.6E-66 T 23-10-2018 Mlab_0400 51137ae253f95e7025771eea849ac48e 377 Pfam PF13191 AAA ATPase domain 27 299 2.0E-22 T 23-10-2018 Mlab_0400 51137ae253f95e7025771eea849ac48e 377 Hamap MF_01407 ORC1-type DNA replication protein. 5 373 21.437 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea Mlab_0400 51137ae253f95e7025771eea849ac48e 377 SUPERFAMILY SSF46785 287 373 4.35E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1436 d5e03c26d567aa2617a39c9df282bf70 247 SUPERFAMILY SSF52540 6 239 3.3E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1436 d5e03c26d567aa2617a39c9df282bf70 247 SMART SM00382 31 218 6.0E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1436 d5e03c26d567aa2617a39c9df282bf70 247 PIRSF PIRSF039085 3 246 9.4E-98 T 23-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 Mlab_1436 d5e03c26d567aa2617a39c9df282bf70 247 Gene3D G3DSA:3.40.50.300 5 244 1.0E-74 T 23-10-2018 Mlab_1436 d5e03c26d567aa2617a39c9df282bf70 247 Pfam PF00005 ABC transporter 22 170 7.8E-36 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1436 d5e03c26d567aa2617a39c9df282bf70 247 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0829 0b1a978f1de5a831dc60536193dc53e6 138 Pfam PF03061 Thioesterase superfamily 49 120 1.6E-8 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Mlab_0829 0b1a978f1de5a831dc60536193dc53e6 138 Gene3D G3DSA:3.10.129.10 7 138 1.5E-27 T 23-10-2018 Mlab_0829 0b1a978f1de5a831dc60536193dc53e6 138 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 117 1.4E-13 T 23-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 Mlab_0829 0b1a978f1de5a831dc60536193dc53e6 138 SUPERFAMILY SSF54637 2 136 7.95E-25 T 23-10-2018 IPR029069 HotDog domain superfamily Mlab_1008 ac6322fd022a6cd18406a6c79ea920a4 270 Gene3D G3DSA:3.40.50.150 9 181 2.0E-22 T 23-10-2018 Mlab_1008 ac6322fd022a6cd18406a6c79ea920a4 270 SUPERFAMILY SSF53335 22 137 1.94E-23 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1008 ac6322fd022a6cd18406a6c79ea920a4 270 Pfam PF13847 Methyltransferase domain 55 165 1.5E-18 T 23-10-2018 IPR025714 Methyltransferase domain Mlab_1347 72532b125fcd8fa015128e4ec49c45b5 465 Gene3D G3DSA:3.90.1640.30 2 190 6.6E-14 T 23-10-2018 Mlab_1347 72532b125fcd8fa015128e4ec49c45b5 465 SUPERFAMILY SSF64182 4 459 5.06E-60 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily Mlab_1347 72532b125fcd8fa015128e4ec49c45b5 465 Pfam PF02272 DHHA1 domain 346 454 1.3E-16 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Mlab_0676 95e5123e0a43aa22e7b4fb902d207916 226 Gene3D G3DSA:3.30.200.20 1 98 2.0E-23 T 23-10-2018 Mlab_0676 95e5123e0a43aa22e7b4fb902d207916 226 Gene3D G3DSA:3.30.470.20 99 219 1.9E-29 T 23-10-2018 Mlab_0676 95e5123e0a43aa22e7b4fb902d207916 226 SUPERFAMILY SSF56104 1 214 1.24E-48 T 23-10-2018 Mlab_0676 95e5123e0a43aa22e7b4fb902d207916 226 Pfam PF01259 SAICAR synthetase 4 213 1.6E-28 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Mlab_0912 cfb4d0ba3596788e3042c06b4083fbf4 302 Pfam PF13197 Protein of unknown function (DUF4013) 81 249 2.3E-21 T 23-10-2018 IPR025098 Protein of unknown function DUF4013 Mlab_0608 49f6b194603ee7481c2484304a683d75 158 SUPERFAMILY SSF52016 3 153 1.47E-48 T 23-10-2018 Mlab_0608 49f6b194603ee7481c2484304a683d75 158 Pfam PF00694 Aconitase C-terminal domain 45 103 6.3E-23 T 23-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Mlab_0608 49f6b194603ee7481c2484304a683d75 158 Gene3D G3DSA:3.20.19.10 1 154 2.0E-56 T 23-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Mlab_0608 49f6b194603ee7481c2484304a683d75 158 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 1 157 35.286 T 23-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 Mlab_0608 49f6b194603ee7481c2484304a683d75 158 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 2 153 1.0E-62 T 23-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 28 401 1.0E-124 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 182 196 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 SUPERFAMILY SSF55035 125 238 1.96E-37 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 Gene3D G3DSA:3.30.70.420 125 238 3.1E-118 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 Gene3D G3DSA:3.90.770.10 71 387 3.1E-118 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 321 342 6.0E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 180 198 6.0E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 91 111 6.0E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 219 244 6.0E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 269 295 6.0E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 60 81 6.0E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 5 401 6.2E-150 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 SUPERFAMILY SSF56542 3 391 2.35E-78 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_1655 6ddd3fefd37a75eb22cc94ebabf42d16 404 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 333 340 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Mlab_0658 81ed2019b16026956ffb6cf82a41a067 190 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 9 76 7.0E-16 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 Mlab_0658 81ed2019b16026956ffb6cf82a41a067 190 SUPERFAMILY SSF88798 1 78 1.96E-20 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 Mlab_0658 81ed2019b16026956ffb6cf82a41a067 190 Gene3D G3DSA:2.40.50.140 82 190 4.2E-27 T 23-10-2018 Mlab_0658 81ed2019b16026956ffb6cf82a41a067 190 SMART SM00316 80 166 8.1E-11 T 23-10-2018 IPR022967 RNA-binding domain, S1 Mlab_0658 81ed2019b16026956ffb6cf82a41a067 190 Gene3D G3DSA:3.30.1490.120 1 81 1.0E-24 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 Mlab_0658 81ed2019b16026956ffb6cf82a41a067 190 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 7.4E-66 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 Mlab_0658 81ed2019b16026956ffb6cf82a41a067 190 SUPERFAMILY SSF50249 81 180 3.06E-22 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0658 81ed2019b16026956ffb6cf82a41a067 190 Pfam PF00575 S1 RNA binding domain 83 153 2.2E-11 T 23-10-2018 IPR003029 S1 domain GO:0003676 Mlab_1268 fe64c1c7963459092d26fb8b94b31a90 377 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 309 321 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site Mlab_1268 fe64c1c7963459092d26fb8b94b31a90 377 SUPERFAMILY SSF55920 136 375 1.31E-45 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like Mlab_1268 fe64c1c7963459092d26fb8b94b31a90 377 Gene3D G3DSA:3.90.230.10 137 376 2.8E-54 T 23-10-2018 Mlab_1268 fe64c1c7963459092d26fb8b94b31a90 377 Pfam PF00557 Metallopeptidase family M24 144 361 1.2E-42 T 23-10-2018 IPR000994 Peptidase M24 Mlab_1268 fe64c1c7963459092d26fb8b94b31a90 377 Gene3D G3DSA:3.40.350.10 1 136 3.1E-8 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Mlab_1268 fe64c1c7963459092d26fb8b94b31a90 377 SUPERFAMILY SSF53092 4 136 8.37E-6 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 SUPERFAMILY SSF52540 470 743 2.36E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 SMART SM01073 8 91 9.1E-28 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 746 9.1E-293 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 SUPERFAMILY SSF50692 2 88 1.24E-20 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 107 181 2.9E-8 T 23-10-2018 IPR004201 CDC48, domain 2 Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 SMART SM01072 106 188 1.3E-11 T 23-10-2018 IPR004201 CDC48, domain 2 Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 ProSitePatterns PS00674 AAA-protein family signature. 340 358 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 Gene3D G3DSA:3.40.50.300 470 744 7.2E-98 T 23-10-2018 Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 SUPERFAMILY SSF54585 91 205 5.23E-9 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 9 88 4.7E-20 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 Gene3D G3DSA:1.10.8.60 645 734 7.2E-98 T 23-10-2018 Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 SMART SM00382 236 372 1.2E-23 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 SMART SM00382 508 646 8.5E-22 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 Gene3D G3DSA:3.40.50.300 196 370 3.8E-67 T 23-10-2018 Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 SUPERFAMILY SSF52540 200 464 3.16E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 Gene3D G3DSA:1.10.8.60 371 465 2.6E-28 T 23-10-2018 Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 240 369 9.4E-50 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 513 643 1.7E-46 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 Gene3D G3DSA:2.40.40.20 1 89 9.2E-22 T 23-10-2018 Mlab_1124 7fe9007bf438ff5e278c931bcc020305 810 ProSitePatterns PS00674 AAA-protein family signature. 614 632 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Mlab_1038 b46d2c0f0eb0745b92721a68decea69f 446 Pfam PF00202 Aminotransferase class-III 30 422 2.7E-73 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Mlab_1038 b46d2c0f0eb0745b92721a68decea69f 446 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 14 428 4.1E-133 T 23-10-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 Mlab_1038 b46d2c0f0eb0745b92721a68decea69f 446 PIRSF PIRSF000521 8 140 0.013 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Mlab_1038 b46d2c0f0eb0745b92721a68decea69f 446 PIRSF PIRSF000521 133 425 7.3E-29 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Mlab_1038 b46d2c0f0eb0745b92721a68decea69f 446 SUPERFAMILY SSF53383 20 423 1.16E-100 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_1038 b46d2c0f0eb0745b92721a68decea69f 446 Gene3D G3DSA:3.90.1150.10 21 417 4.1E-103 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_1038 b46d2c0f0eb0745b92721a68decea69f 446 Gene3D G3DSA:3.40.640.10 66 325 4.1E-103 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_1038 b46d2c0f0eb0745b92721a68decea69f 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 243 279 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Mlab_1290 ae96a03669a00399b1147e817f68f629 350 Pfam PF01032 FecCD transport family 21 342 1.2E-92 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Mlab_1290 ae96a03669a00399b1147e817f68f629 350 SUPERFAMILY SSF81345 8 342 7.72E-78 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_1290 ae96a03669a00399b1147e817f68f629 350 Gene3D G3DSA:1.10.3470.10 7 348 4.8E-96 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_0330 c62756d88ed3c865b25db4dc8861f426 287 Pfam PF00924 Mechanosensitive ion channel 71 267 5.3E-35 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Mlab_0330 c62756d88ed3c865b25db4dc8861f426 287 SUPERFAMILY SSF50182 110 173 9.48E-16 T 23-10-2018 IPR010920 LSM domain superfamily Mlab_0330 c62756d88ed3c865b25db4dc8861f426 287 Gene3D G3DSA:2.30.30.60 126 174 2.8E-13 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily Mlab_0330 c62756d88ed3c865b25db4dc8861f426 287 SUPERFAMILY SSF82861 27 109 4.32E-7 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 Mlab_1024 e4cd5247861c7b7ffef5529913e9911e 335 Gene3D G3DSA:3.40.50.300 1 233 1.2E-71 T 23-10-2018 Mlab_1024 e4cd5247861c7b7ffef5529913e9911e 335 SUPERFAMILY SSF52540 1 236 1.6E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1024 e4cd5247861c7b7ffef5529913e9911e 335 SMART SM00382 25 215 3.7E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1024 e4cd5247861c7b7ffef5529913e9911e 335 Pfam PF00005 ABC transporter 16 158 9.3E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1024 e4cd5247861c7b7ffef5529913e9911e 335 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0222 9490fa65d507986556cb5face071f363 94 ProDom PD028584 ARCHAEA MJ0453 UNCHARACTERIZED MA0126 MA0129 1 88 3.0E-19 T 23-10-2018 IPR012031 Uncharacterised conserved protein UCP006577 Mlab_0222 9490fa65d507986556cb5face071f363 94 PIRSF PIRSF006577 1 93 3.0E-29 T 23-10-2018 IPR012031 Uncharacterised conserved protein UCP006577 Mlab_0222 9490fa65d507986556cb5face071f363 94 Pfam PF08979 Domain of unknown function (DUF1894) 1 87 5.1E-33 T 23-10-2018 IPR012031 Uncharacterised conserved protein UCP006577 Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 Gene3D G3DSA:1.10.150.20 634 688 2.4E-15 T 23-10-2018 Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 SUPERFAMILY SSF158702 494 691 1.78E-60 T 23-10-2018 Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 Pfam PF00271 Helicase conserved C-terminal domain 230 373 6.7E-9 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 Gene3D G3DSA:1.10.3380.30 413 632 1.5E-61 T 23-10-2018 Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 Pfam PF14520 Helix-hairpin-helix domain 638 688 1.2E-7 T 23-10-2018 Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 SMART SM00490 288 375 5.7E-17 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 SUPERFAMILY SSF46785 406 493 1.93E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 9 689 31.356 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 Gene3D G3DSA:3.40.50.300 200 401 8.6E-52 T 23-10-2018 Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 Gene3D G3DSA:3.40.50.300 7 199 9.3E-64 T 23-10-2018 Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 Pfam PF00270 DEAD/DEAH box helicase 26 179 6.0E-24 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 SUPERFAMILY SSF52540 196 389 6.05E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 SMART SM00487 20 208 4.2E-28 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Mlab_1751 7470a22f358fdb9daeca2d177631e12b 726 SUPERFAMILY SSF52540 2 189 7.44E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1389 64d0f5681edd6be158eed35f3e8bbdc3 574 SUPERFAMILY SSF50692 3 119 1.04E-15 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Mlab_1389 64d0f5681edd6be158eed35f3e8bbdc3 574 SUPERFAMILY SSF53706 145 562 5.63E-55 T 23-10-2018 Mlab_1389 64d0f5681edd6be158eed35f3e8bbdc3 574 Gene3D G3DSA:3.40.228.10 255 362 1.9E-17 T 23-10-2018 Mlab_1389 64d0f5681edd6be158eed35f3e8bbdc3 574 Gene3D G3DSA:2.40.40.20 1 124 8.6E-36 T 23-10-2018 Mlab_1389 64d0f5681edd6be158eed35f3e8bbdc3 574 TIGRFAM TIGR03129 one_C_dehyd_B: formylmethanofuran dehydrogenase subunit B 148 564 7.0E-164 T 23-10-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 Mlab_1389 64d0f5681edd6be158eed35f3e8bbdc3 574 Pfam PF00384 Molybdopterin oxidoreductase 188 354 1.8E-5 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_1389 64d0f5681edd6be158eed35f3e8bbdc3 574 Pfam PF01568 Molydopterin dinucleotide binding domain 4 100 2.5E-10 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Mlab_1566 ac6f820bd90f54a5d4f0ebcb14423b94 195 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 192 35.483 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 Mlab_1566 ac6f820bd90f54a5d4f0ebcb14423b94 195 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 191 3.3E-48 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 Mlab_1566 ac6f820bd90f54a5d4f0ebcb14423b94 195 SUPERFAMILY SSF75217 1 192 5.89E-55 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases Mlab_1566 ac6f820bd90f54a5d4f0ebcb14423b94 195 Gene3D G3DSA:3.40.1280.10 1 193 7.6E-62 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Mlab_0858 4e736582df524746856df67bfbc4fa97 470 SUPERFAMILY SSF103473 11 467 2.09E-60 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_0858 4e736582df524746856df67bfbc4fa97 470 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 421 7.4E-69 T 23-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 Mlab_0858 4e736582df524746856df67bfbc4fa97 470 Gene3D G3DSA:1.20.1250.20 256 468 1.6E-16 T 23-10-2018 Mlab_0858 4e736582df524746856df67bfbc4fa97 470 Gene3D G3DSA:1.20.1720.10 14 218 2.0E-41 T 23-10-2018 Mlab_0858 4e736582df524746856df67bfbc4fa97 470 Pfam PF07690 Major Facilitator Superfamily 19 409 1.5E-49 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_0858 4e736582df524746856df67bfbc4fa97 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 128 5.9E-9 T 23-10-2018 Mlab_0858 4e736582df524746856df67bfbc4fa97 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 5.9E-9 T 23-10-2018 Mlab_0858 4e736582df524746856df67bfbc4fa97 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 5.9E-9 T 23-10-2018 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 SMART SM01096 409 524 6.5E-49 T 23-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 692 706 - T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Gene3D G3DSA:3.40.50.20 501 638 2.0E-55 T 23-10-2018 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Gene3D G3DSA:3.30.470.20 648 917 1.6E-112 T 23-10-2018 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1044 12.265 T 23-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 292 299 - T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1034 0.0 T 23-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1051 13.742 T 23-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 656 857 1.3E-38 T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 126 329 6.2E-67 T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 292 321 1.4E-61 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.4E-61 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 202 221 1.4E-61 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 237 254 1.4E-61 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 166 178 1.4E-61 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 374 392 1.4E-61 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.4E-61 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 413 524 4.4E-32 T 23-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 821 828 - T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 SUPERFAMILY SSF48108 391 530 1.22E-37 T 23-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 SUPERFAMILY SSF56059 656 915 1.06E-102 T 23-10-2018 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Gene3D G3DSA:3.30.470.20 119 389 1.4E-110 T 23-10-2018 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Pfam PF02142 MGS-like domain 937 1023 7.1E-19 T 23-10-2018 IPR011607 Methylglyoxal synthase-like domain Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Gene3D G3DSA:3.30.1490.20 139 208 1.4E-110 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Gene3D G3DSA:1.10.1030.10 390 498 2.5E-19 T 23-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 SUPERFAMILY SSF56059 126 395 6.89E-101 T 23-10-2018 Mlab_0283 6c21f661027a8b34903df038c99504de 1053 SMART SM00851 937 1023 3.6E-27 T 23-10-2018 IPR011607 Methylglyoxal synthase-like domain Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Gene3D G3DSA:3.40.50.1380 918 1053 1.9E-40 T 23-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Mlab_0283 6c21f661027a8b34903df038c99504de 1053 SUPERFAMILY SSF52440 1 124 1.11E-43 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Mlab_0283 6c21f661027a8b34903df038c99504de 1053 SUPERFAMILY SSF52335 919 1052 7.33E-36 T 23-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Mlab_0283 6c21f661027a8b34903df038c99504de 1053 SUPERFAMILY SSF52440 532 655 1.17E-43 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Mlab_0283 6c21f661027a8b34903df038c99504de 1053 Gene3D G3DSA:3.40.50.20 1 114 8.7E-44 T 23-10-2018 Mlab_0712 0fac4aa5be34256445d003908cc893b3 338 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 156 317 1.4E-29 T 23-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Mlab_0712 0fac4aa5be34256445d003908cc893b3 338 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 127 1.2E-33 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Mlab_0712 0fac4aa5be34256445d003908cc893b3 338 PIRSF PIRSF000148 1 338 8.7E-92 T 23-10-2018 Mlab_0712 0fac4aa5be34256445d003908cc893b3 338 SUPERFAMILY SSF51735 2 173 1.09E-45 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0712 0fac4aa5be34256445d003908cc893b3 338 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 226 240 - T 23-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Mlab_0712 0fac4aa5be34256445d003908cc893b3 338 Gene3D G3DSA:3.30.360.10 148 315 1.9E-130 T 23-10-2018 Mlab_0712 0fac4aa5be34256445d003908cc893b3 338 SUPERFAMILY SSF55347 145 320 5.06E-37 T 23-10-2018 Mlab_0712 0fac4aa5be34256445d003908cc893b3 338 SMART SM00859 3 129 1.2E-37 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Mlab_0712 0fac4aa5be34256445d003908cc893b3 338 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 2 332 1.1E-124 T 23-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 Mlab_0712 0fac4aa5be34256445d003908cc893b3 338 Gene3D G3DSA:3.40.50.720 4 332 1.9E-130 T 23-10-2018 Mlab_1227 f5ef03c14f473a7231c7f18dcba035dc 170 Gene3D G3DSA:3.40.225.10 3 169 2.8E-25 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Mlab_1227 f5ef03c14f473a7231c7f18dcba035dc 170 Pfam PF10120 Thiamine-phosphate synthase 33 158 2.2E-17 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1227 f5ef03c14f473a7231c7f18dcba035dc 170 SUPERFAMILY SSF53639 8 166 7.46E-30 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Mlab_0384 f7b696d53f9bcf4f1151a50ff45b10e5 232 SUPERFAMILY SSF46785 8 81 2.41E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0384 f7b696d53f9bcf4f1151a50ff45b10e5 232 SUPERFAMILY SSF47979 60 119 3.14E-17 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 Mlab_0384 f7b696d53f9bcf4f1151a50ff45b10e5 232 Gene3D G3DSA:1.10.10.10 4 128 1.2E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0384 f7b696d53f9bcf4f1151a50ff45b10e5 232 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 60 117 8.7E-19 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 Mlab_0384 f7b696d53f9bcf4f1151a50ff45b10e5 232 Gene3D G3DSA:2.30.30.90 175 228 1.7E-8 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain Mlab_0384 f7b696d53f9bcf4f1151a50ff45b10e5 232 SMART SM00529 22 120 9.8E-15 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 Mlab_0384 f7b696d53f9bcf4f1151a50ff45b10e5 232 Pfam PF04023 FeoA domain 158 228 4.1E-9 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Mlab_0384 f7b696d53f9bcf4f1151a50ff45b10e5 232 SMART SM00899 158 228 3.6E-12 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Mlab_0384 f7b696d53f9bcf4f1151a50ff45b10e5 232 SUPERFAMILY SSF50037 173 228 7.78E-10 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal Mlab_1244 c90f6e6c1bda0064686397f224a1b403 275 Gene3D G3DSA:2.170.120.12 38 151 1.3E-82 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1244 c90f6e6c1bda0064686397f224a1b403 275 SMART SM00662 12 270 5.7E-72 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1244 c90f6e6c1bda0064686397f224a1b403 275 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 14 261 1.5E-16 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1244 c90f6e6c1bda0064686397f224a1b403 275 SUPERFAMILY SSF55257 4 273 1.81E-23 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1244 c90f6e6c1bda0064686397f224a1b403 275 Gene3D G3DSA:3.30.70.3110 162 234 1.3E-82 T 23-10-2018 Mlab_1244 c90f6e6c1bda0064686397f224a1b403 275 Pfam PF12838 4Fe-4S dicluster domain 170 218 2.4E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_1244 c90f6e6c1bda0064686397f224a1b403 275 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 44 152 3.2E-29 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1244 c90f6e6c1bda0064686397f224a1b403 275 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 1 273 33.543 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1244 c90f6e6c1bda0064686397f224a1b403 275 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 171 182 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_1244 c90f6e6c1bda0064686397f224a1b403 275 SUPERFAMILY SSF56553 37 153 5.23E-36 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1244 c90f6e6c1bda0064686397f224a1b403 275 Gene3D G3DSA:3.30.1360.10 9 265 1.3E-82 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1221 7e63e7fad1e946baffcc53c66d2ca019 100 SUPERFAMILY SSF159468 3 99 3.27E-21 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1221 7e63e7fad1e946baffcc53c66d2ca019 100 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 99 21.034 T 23-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal Mlab_1221 7e63e7fad1e946baffcc53c66d2ca019 100 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 92 1.5E-17 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1221 7e63e7fad1e946baffcc53c66d2ca019 100 Gene3D G3DSA:3.40.50.10580 1 78 6.7E-23 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1140 2cb5d13bc4ee0c82730c6d596eab9a23 477 Pfam PF02934 GatB/GatE catalytic domain 8 285 6.0E-99 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 Mlab_1140 2cb5d13bc4ee0c82730c6d596eab9a23 477 Gene3D G3DSA:1.10.10.410 419 476 4.6E-18 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal Mlab_1140 2cb5d13bc4ee0c82730c6d596eab9a23 477 SMART SM00845 325 475 1.6E-38 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Mlab_1140 2cb5d13bc4ee0c82730c6d596eab9a23 477 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 5 476 33.951 T 23-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Mlab_1140 2cb5d13bc4ee0c82730c6d596eab9a23 477 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 5 475 8.4E-156 T 23-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Mlab_1140 2cb5d13bc4ee0c82730c6d596eab9a23 477 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 151 165 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 Mlab_1140 2cb5d13bc4ee0c82730c6d596eab9a23 477 Gene3D G3DSA:1.10.150.380 294 395 3.2E-21 T 23-10-2018 Mlab_1140 2cb5d13bc4ee0c82730c6d596eab9a23 477 SUPERFAMILY SSF55931 4 291 7.85E-102 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Mlab_1140 2cb5d13bc4ee0c82730c6d596eab9a23 477 Pfam PF02637 GatB domain 333 475 2.3E-29 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Mlab_1140 2cb5d13bc4ee0c82730c6d596eab9a23 477 SUPERFAMILY SSF89095 294 394 1.36E-20 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 Mlab_0549 f2a99be165335eb8bc67437489fd9745 312 PIRSF PIRSF019164 1 312 1.8E-108 T 23-10-2018 IPR011312 Uncharacterised conserved protein UCP019164, methanogenesis Mlab_0549 f2a99be165335eb8bc67437489fd9745 312 TIGRFAM TIGR03274 methan_mark_7: putative methanogenesis marker protein 7 4 307 1.1E-123 T 23-10-2018 IPR011312 Uncharacterised conserved protein UCP019164, methanogenesis Mlab_0549 f2a99be165335eb8bc67437489fd9745 312 Pfam PF04609 Methyl-coenzyme M reductase operon protein C 4 275 3.9E-119 T 23-10-2018 IPR026327 Methyl-coenzyme M reductase, protein C-like Mlab_1392 0c3f45c594b4ac99d4348fa2b0cbe1be 382 Gene3D G3DSA:3.30.9.10 66 334 1.6E-76 T 23-10-2018 Mlab_1392 0c3f45c594b4ac99d4348fa2b0cbe1be 382 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 277 6.6E-62 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 Mlab_1392 0c3f45c594b4ac99d4348fa2b0cbe1be 382 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 243 258 1.9E-9 T 23-10-2018 Mlab_1392 0c3f45c594b4ac99d4348fa2b0cbe1be 382 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.9E-9 T 23-10-2018 Mlab_1392 0c3f45c594b4ac99d4348fa2b0cbe1be 382 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 258 274 1.9E-9 T 23-10-2018 Mlab_1392 0c3f45c594b4ac99d4348fa2b0cbe1be 382 SUPERFAMILY SSF51905 3 313 9.39E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_1392 0c3f45c594b4ac99d4348fa2b0cbe1be 382 Pfam PF01494 FAD binding domain 3 156 9.8E-7 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 Mlab_1392 0c3f45c594b4ac99d4348fa2b0cbe1be 382 Gene3D G3DSA:3.50.50.60 3 317 1.6E-76 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0637 42621aa224e14165ce037e63fec6db78 329 Pfam PF14520 Helix-hairpin-helix domain 5 59 1.0E-10 T 23-10-2018 Mlab_0637 42621aa224e14165ce037e63fec6db78 329 Gene3D G3DSA:3.40.50.300 73 327 8.1E-74 T 23-10-2018 Mlab_0637 42621aa224e14165ce037e63fec6db78 329 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 3 328 73.45 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 Mlab_0637 42621aa224e14165ce037e63fec6db78 329 SUPERFAMILY SSF47794 5 64 5.81E-13 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 Mlab_0637 42621aa224e14165ce037e63fec6db78 329 Pfam PF08423 Rad51 65 327 3.2E-79 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 Mlab_0637 42621aa224e14165ce037e63fec6db78 329 SUPERFAMILY SSF52540 81 327 1.49E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0637 42621aa224e14165ce037e63fec6db78 329 PIRSF PIRSF005856 1 329 1.3E-116 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 Mlab_0637 42621aa224e14165ce037e63fec6db78 329 SMART SM00382 99 298 4.3E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0637 42621aa224e14165ce037e63fec6db78 329 Gene3D G3DSA:1.10.150.20 5 72 1.7E-21 T 23-10-2018 Mlab_0637 42621aa224e14165ce037e63fec6db78 329 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 5 327 4.8E-140 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 Mlab_0937 d83286a4bed56d6315dfa11aa252d961 225 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 1 221 4.3E-62 T 23-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 Mlab_0937 d83286a4bed56d6315dfa11aa252d961 225 TIGRFAM TIGR01508 rib_reduct_arch: diaminohydroxyphosphoribosylaminopyrimidine reductase 3 220 1.9E-71 T 23-10-2018 IPR006401 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal GO:0016491|GO:0055114 KEGG: 00740+1.1.1.302|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0937 d83286a4bed56d6315dfa11aa252d961 225 Gene3D G3DSA:3.40.430.10 1 223 7.0E-66 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Mlab_0937 d83286a4bed56d6315dfa11aa252d961 225 Pfam PF01872 RibD C-terminal domain 3 219 8.9E-53 T 23-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Mlab_0937 d83286a4bed56d6315dfa11aa252d961 225 SUPERFAMILY SSF53597 1 221 4.06E-53 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Mlab_0878 f7d19d9856703136d5c33066c0c8a16c 321 Gene3D G3DSA:3.40.50.300 8 210 1.7E-37 T 23-10-2018 Mlab_0878 f7d19d9856703136d5c33066c0c8a16c 321 PIRSF PIRSF002849 1 321 1.3E-104 T 23-10-2018 Mlab_0878 f7d19d9856703136d5c33066c0c8a16c 321 SUPERFAMILY SSF52540 14 293 3.54E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0878 f7d19d9856703136d5c33066c0c8a16c 321 Gene3D G3DSA:1.10.8.300 211 318 4.4E-31 T 23-10-2018 Mlab_0878 f7d19d9856703136d5c33066c0c8a16c 321 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 45 174 2.5E-48 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Mlab_1280 d64f8e663f08d8af03aea2e364545be1 458 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 38 455 22.065 T 23-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 Mlab_1280 d64f8e663f08d8af03aea2e364545be1 458 Pfam PF02601 Exonuclease VII, large subunit 171 452 4.7E-75 T 23-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 Mlab_1280 d64f8e663f08d8af03aea2e364545be1 458 Pfam PF13742 OB-fold nucleic acid binding domain 41 138 3.9E-23 T 23-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 Mlab_1280 d64f8e663f08d8af03aea2e364545be1 458 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 42 454 4.3E-110 T 23-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 Mlab_1068 938f035ed67f5f6c91d2d8be1065f894 568 Gene3D G3DSA:3.90.390.10 4 111 1.3E-42 T 23-10-2018 IPR015811 Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 1 GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1068 938f035ed67f5f6c91d2d8be1065f894 568 Pfam PF02745 Methyl-coenzyme M reductase alpha subunit, N-terminal domain 8 278 4.4E-154 T 23-10-2018 IPR003183 Methyl-coenzyme M reductase, alpha subunit, N-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1068 938f035ed67f5f6c91d2d8be1065f894 568 SUPERFAMILY SSF48081 280 567 4.71E-144 T 23-10-2018 IPR008924 Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1068 938f035ed67f5f6c91d2d8be1065f894 568 Gene3D G3DSA:1.20.840.10 287 554 1.1E-137 T 23-10-2018 IPR008924 Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1068 938f035ed67f5f6c91d2d8be1065f894 568 SUPERFAMILY SSF55088 5 279 5.1E-144 T 23-10-2018 IPR009024 Methyl-coenzyme M reductase, ferredoxin-like fold GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1068 938f035ed67f5f6c91d2d8be1065f894 568 Pfam PF02249 Methyl-coenzyme M reductase alpha subunit, C-terminal domain 326 459 1.9E-70 T 23-10-2018 IPR009047 Methyl-coenzyme M reductase, alpha subunit, C-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1068 938f035ed67f5f6c91d2d8be1065f894 568 TIGRFAM TIGR03256 met_CoM_red_alp: methyl-coenzyme M reductase, alpha subunit 8 567 8.4E-289 T 23-10-2018 IPR016212 Methyl coenzyme M reductase, alpha subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1068 938f035ed67f5f6c91d2d8be1065f894 568 PIRSF PIRSF000262 3 568 3.9E-296 T 23-10-2018 IPR016212 Methyl coenzyme M reductase, alpha subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1068 938f035ed67f5f6c91d2d8be1065f894 568 Gene3D G3DSA:3.30.70.470 112 286 1.4E-90 T 23-10-2018 IPR015823 Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 2 GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_0258 a31c160b7a10c8917da82bd744dc0fc6 182 Gene3D G3DSA:1.10.1760.20 5 171 3.0E-6 T 23-10-2018 Mlab_0258 a31c160b7a10c8917da82bd744dc0fc6 182 Pfam PF09819 ABC-type cobalt transport system, permease component 16 116 1.6E-8 T 23-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted Mlab_1107 d2bdb9b09528b6765e988cf473a19e13 188 Pfam PF04289 Protein of unknown function (DUF447) 11 184 1.2E-52 T 23-10-2018 IPR007386 Protein of unknown function DUF447 Mlab_1107 d2bdb9b09528b6765e988cf473a19e13 188 Gene3D G3DSA:2.30.110.10 2 130 6.2E-24 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Mlab_1107 d2bdb9b09528b6765e988cf473a19e13 188 Gene3D G3DSA:1.20.58.290 131 188 3.7E-25 T 23-10-2018 Mlab_1107 d2bdb9b09528b6765e988cf473a19e13 188 SUPERFAMILY SSF50475 4 185 2.85E-46 T 23-10-2018 Mlab_1107 d2bdb9b09528b6765e988cf473a19e13 188 PIRSF PIRSF018747 5 90 6.6E-7 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 Mlab_1107 d2bdb9b09528b6765e988cf473a19e13 188 PIRSF PIRSF018747 101 185 0.082 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 Pfam PF01411 tRNA synthetases class II (A) 61 600 5.2E-118 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 SUPERFAMILY SSF55681 58 260 2.73E-54 T 23-10-2018 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 3 907 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 205 216 2.3E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 127 138 2.3E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 336 352 2.3E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 241 254 2.3E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 360 373 2.3E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 699 741 7.5E-13 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 SMART SM00863 699 741 9.0E-16 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 Gene3D G3DSA:3.10.310.40 808 910 1.4E-14 T 23-10-2018 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 Gene3D G3DSA:3.30.930.10 1 256 3.0E-102 T 23-10-2018 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 SUPERFAMILY SSF101353 306 498 2.48E-42 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 Gene3D G3DSA:3.30.980.10 606 742 8.2E-42 T 23-10-2018 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 Gene3D G3DSA:2.40.30.130 501 596 5.9E-27 T 23-10-2018 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 Pfam PF02272 DHHA1 domain 778 907 5.3E-18 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 890 2.8E-207 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 SUPERFAMILY SSF50447 510 594 1.41E-16 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 SUPERFAMILY SSF55186 596 753 4.19E-40 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 Gene3D G3DSA:3.30.54.20 668 722 8.2E-42 T 23-10-2018 Mlab_1380 97e627cf8160eceaacc6e1844e9a235c 913 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 5 905 22.766 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 Mlab_0188 31c87a736518b87d35896c64bb6f9a88 252 Pfam PF00899 ThiF family 12 238 2.0E-62 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 Mlab_0188 31c87a736518b87d35896c64bb6f9a88 252 Gene3D G3DSA:3.40.50.720 5 245 8.5E-77 T 23-10-2018 Mlab_0188 31c87a736518b87d35896c64bb6f9a88 252 SUPERFAMILY SSF69572 7 239 1.83E-79 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 Mlab_0822 6db675ce67bf2d80f59d98c840422d92 455 Gene3D G3DSA:3.40.710.10 1 313 1.7E-74 T 23-10-2018 Mlab_0822 6db675ce67bf2d80f59d98c840422d92 455 SUPERFAMILY SSF56601 1 308 2.9E-70 T 23-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Mlab_0822 6db675ce67bf2d80f59d98c840422d92 455 Pfam PF11954 Domain of unknown function (DUF3471) 362 441 1.0E-8 T 23-10-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal Mlab_0822 6db675ce67bf2d80f59d98c840422d92 455 Pfam PF00144 Beta-lactamase 1 308 3.8E-50 T 23-10-2018 IPR001466 Beta-lactamase-related Mlab_0822 6db675ce67bf2d80f59d98c840422d92 455 Gene3D G3DSA:2.40.128.600 357 453 4.8E-16 T 23-10-2018 Mlab_1641 2090564c73197a58581b1fd2df1806d7 295 SUPERFAMILY SSF53633 3 290 3.27E-87 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_1641 2090564c73197a58581b1fd2df1806d7 295 PIRSF PIRSF000728 6 290 3.3E-100 T 23-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Mlab_1641 2090564c73197a58581b1fd2df1806d7 295 Pfam PF00696 Amino acid kinase family 21 267 2.6E-46 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Mlab_1641 2090564c73197a58581b1fd2df1806d7 295 Hamap MF_00082 Acetylglutamate kinase [argB]. 20 283 48.95 T 23-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Mlab_1641 2090564c73197a58581b1fd2df1806d7 295 Gene3D G3DSA:3.40.1160.10 1 293 4.9E-97 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_1641 2090564c73197a58581b1fd2df1806d7 295 PRINTS PR00474 Glutamate 5-kinase family signature 52 66 5.5E-10 T 23-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Mlab_1641 2090564c73197a58581b1fd2df1806d7 295 PRINTS PR00474 Glutamate 5-kinase family signature 240 260 5.5E-10 T 23-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Mlab_1641 2090564c73197a58581b1fd2df1806d7 295 PRINTS PR00474 Glutamate 5-kinase family signature 189 216 5.5E-10 T 23-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Mlab_1641 2090564c73197a58581b1fd2df1806d7 295 TIGRFAM TIGR00761 argB: acetylglutamate kinase 22 265 7.2E-72 T 23-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Mlab_0449 d21db5b425f2de6f4d5cf17f86298044 284 TIGRFAM TIGR04125 exosort_PGF_TRM: archaeosortase A 10 275 2.1E-54 T 23-10-2018 IPR014522 Archaeosortase A Mlab_0449 d21db5b425f2de6f4d5cf17f86298044 284 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 152 257 1.7E-17 T 23-10-2018 IPR026392 Exosortase/Archaeosortase domain Mlab_0449 d21db5b425f2de6f4d5cf17f86298044 284 PIRSF PIRSF025737 1 283 8.1E-33 T 23-10-2018 IPR014522 Archaeosortase A Mlab_1154 fccdbb24448d7198a1ba7e9664c69a4e 219 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 218 32.996 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 Mlab_1154 fccdbb24448d7198a1ba7e9664c69a4e 219 Pfam PF13483 Beta-lactamase superfamily domain 2 181 9.8E-27 T 23-10-2018 Mlab_1154 fccdbb24448d7198a1ba7e9664c69a4e 219 Gene3D G3DSA:3.60.15.10 1 218 7.9E-62 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1154 fccdbb24448d7198a1ba7e9664c69a4e 219 SUPERFAMILY SSF56281 1 200 2.3E-32 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1154 fccdbb24448d7198a1ba7e9664c69a4e 219 SMART SM00849 7 181 2.1E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0512 110f879e0d8109e4a7647ca9c751c7a0 251 SUPERFAMILY SSF56300 21 178 1.06E-14 T 23-10-2018 Mlab_0512 110f879e0d8109e4a7647ca9c751c7a0 251 Pfam PF00149 Calcineurin-like phosphoesterase 21 116 4.6E-6 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Mlab_0512 110f879e0d8109e4a7647ca9c751c7a0 251 PIRSF PIRSF000887 1 246 1.3E-43 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 Mlab_0512 110f879e0d8109e4a7647ca9c751c7a0 251 Gene3D G3DSA:3.60.21.10 19 145 6.3E-11 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like Mlab_1391 924f0cc5cd55b68b7f2e0e18dd25f888 310 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 19 202 5.0E-70 T 23-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 Mlab_1391 924f0cc5cd55b68b7f2e0e18dd25f888 310 Gene3D G3DSA:3.40.50.300 2 279 4.6E-78 T 23-10-2018 Mlab_1391 924f0cc5cd55b68b7f2e0e18dd25f888 310 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1391 924f0cc5cd55b68b7f2e0e18dd25f888 310 Pfam PF00005 ABC transporter 21 167 6.2E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1391 924f0cc5cd55b68b7f2e0e18dd25f888 310 SUPERFAMILY SSF52540 3 228 6.85E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1391 924f0cc5cd55b68b7f2e0e18dd25f888 310 SMART SM00382 30 216 5.4E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1568 3a84985ae0bf540eb48ef864f65a1489 98 Gene3D G3DSA:2.30.30.70 1 96 2.1E-36 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1568 3a84985ae0bf540eb48ef864f65a1489 98 ProSitePatterns PS01171 Ribosomal protein L21e signature. 37 62 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1568 3a84985ae0bf540eb48ef864f65a1489 98 Pfam PF01157 Ribosomal protein L21e 4 94 1.2E-30 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1568 3a84985ae0bf540eb48ef864f65a1489 98 SUPERFAMILY SSF50104 4 95 1.11E-31 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily Mlab_1568 3a84985ae0bf540eb48ef864f65a1489 98 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 2 96 26.883 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 Gene3D G3DSA:3.10.580.10 284 410 4.1E-17 T 23-10-2018 Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 SUPERFAMILY SSF52540 55 288 1.5E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 Pfam PF00005 ABC transporter 61 209 2.0E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 SMART SM00116 300 348 14.0 T 23-10-2018 IPR000644 CBS domain Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 SMART SM00116 360 407 0.029 T 23-10-2018 IPR000644 CBS domain Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 ProSitePatterns PS00211 ABC transporters family signature. 182 196 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 Gene3D G3DSA:3.40.50.300 44 283 1.2E-73 T 23-10-2018 Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 SUPERFAMILY SSF54631 291 407 1.42E-21 T 23-10-2018 Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 54 407 3.7E-137 T 23-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 SMART SM00382 70 267 1.5E-19 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 Pfam PF00571 CBS domain 354 407 2.7E-9 T 23-10-2018 IPR000644 CBS domain Mlab_1060 7e76f15be440472ac5db7ed21e0fce80 413 Pfam PF00571 CBS domain 293 347 3.7E-4 T 23-10-2018 IPR000644 CBS domain Mlab_0131 fb0aa008eef087c99c91e71d7aa26da6 328 Pfam PF03099 Biotin/lipoate A/B protein ligase family 107 216 4.4E-12 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Mlab_0131 fb0aa008eef087c99c91e71d7aa26da6 328 SUPERFAMILY SSF55681 76 278 5.68E-46 T 23-10-2018 Mlab_0131 fb0aa008eef087c99c91e71d7aa26da6 328 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 7 328 30.941 T 23-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 Mlab_0131 fb0aa008eef087c99c91e71d7aa26da6 328 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 85 327 6.4E-53 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Mlab_0131 fb0aa008eef087c99c91e71d7aa26da6 328 Gene3D G3DSA:1.10.10.10 2 63 2.7E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0131 fb0aa008eef087c99c91e71d7aa26da6 328 Pfam PF08279 HTH domain 20 59 8.8E-10 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 Mlab_0131 fb0aa008eef087c99c91e71d7aa26da6 328 SUPERFAMILY SSF50037 284 327 3.98E-9 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal Mlab_0131 fb0aa008eef087c99c91e71d7aa26da6 328 Gene3D G3DSA:2.30.30.100 282 327 1.4E-14 T 23-10-2018 Mlab_0131 fb0aa008eef087c99c91e71d7aa26da6 328 SUPERFAMILY SSF46785 7 62 1.57E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0131 fb0aa008eef087c99c91e71d7aa26da6 328 Gene3D G3DSA:3.30.930.10 70 280 4.1E-48 T 23-10-2018 Mlab_0131 fb0aa008eef087c99c91e71d7aa26da6 328 Pfam PF02237 Biotin protein ligase C terminal domain 284 327 2.2E-7 T 23-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Mlab_1562 b0ca842da1ec3f1c21abcc5c2b44880c 254 Pfam PF02240 Methyl-coenzyme M reductase gamma subunit 5 250 1.1E-125 T 23-10-2018 IPR003178 Methyl-coenzyme M reductase, gamma subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1562 b0ca842da1ec3f1c21abcc5c2b44880c 254 SUPERFAMILY SSF55088 6 252 8.63E-120 T 23-10-2018 IPR009024 Methyl-coenzyme M reductase, ferredoxin-like fold GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1562 b0ca842da1ec3f1c21abcc5c2b44880c 254 TIGRFAM TIGR03259 met_CoM_red_gam: methyl-coenzyme M reductase, gamma subunit 6 249 3.6E-106 T 23-10-2018 IPR003178 Methyl-coenzyme M reductase, gamma subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1562 b0ca842da1ec3f1c21abcc5c2b44880c 254 Gene3D G3DSA:3.90.320.20 1 254 1.9E-115 T 23-10-2018 IPR036994 Methyl-coenzyme M reductase, gamma subunit superfamily GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1562 b0ca842da1ec3f1c21abcc5c2b44880c 254 ProDom PD005845 GAMMA SUBUNIT M REDUCTASE METHYL COENZYME METHYL-COENZYME TRANSFERASE SULFOETHYLTHIOTRANSFERASE COENZYME-B 10 251 6.0E-119 T 23-10-2018 IPR003178 Methyl-coenzyme M reductase, gamma subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 Gene3D G3DSA:3.40.50.10490 16 202 1.7E-67 T 23-10-2018 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 Pfam PF00318 Ribosomal protein S2 21 112 4.7E-11 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 Pfam PF00318 Ribosomal protein S2 119 181 7.2E-12 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 14 194 1.4E-78 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 120 144 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 9 202 45.835 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 SUPERFAMILY SSF52313 13 198 8.11E-59 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 17 28 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 PRINTS PR00395 Ribosomal protein S2 signature 17 35 4.7E-25 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 PRINTS PR00395 Ribosomal protein S2 signature 137 148 4.7E-25 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 PRINTS PR00395 Ribosomal protein S2 signature 158 172 4.7E-25 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 PRINTS PR00395 Ribosomal protein S2 signature 47 56 4.7E-25 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 PRINTS PR00395 Ribosomal protein S2 signature 120 137 4.7E-25 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1237 52a42221471b2bc71d5d8b7b2fc37926 202 PRINTS PR00395 Ribosomal protein S2 signature 95 112 4.7E-25 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0037 5e062617bc58f5fdff44a0484ece5508 68 SMART SM00530 4 59 9.0E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_0037 5e062617bc58f5fdff44a0484ece5508 68 SUPERFAMILY SSF47413 3 64 8.19E-17 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Mlab_0037 5e062617bc58f5fdff44a0484ece5508 68 Gene3D G3DSA:1.10.260.40 1 64 1.1E-24 T 23-10-2018 Mlab_0037 5e062617bc58f5fdff44a0484ece5508 68 Pfam PF01381 Helix-turn-helix 5 59 4.5E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 4 190 7.0E-73 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 Gene3D G3DSA:3.40.50.620 194 388 7.4E-73 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 Pfam PF00117 Glutamine amidotransferase class-I 6 185 1.0E-37 T 23-10-2018 IPR017926 Glutamine amidotransferase Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 1 508 52.653 T 23-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 Gene3D G3DSA:3.40.50.880 1 190 2.9E-53 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 4 18 1.0E-5 T 23-10-2018 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 1.0E-5 T 23-10-2018 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 1.0E-5 T 23-10-2018 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 Gene3D G3DSA:3.30.300.10 389 508 1.8E-52 T 23-10-2018 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 198 508 1.2E-149 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 Pfam PF00958 GMP synthase C terminal domain 416 507 5.8E-44 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 SUPERFAMILY SSF52402 178 430 1.67E-55 T 23-10-2018 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 Pfam PF02540 NAD synthase 205 277 8.9E-6 T 23-10-2018 IPR022310 NAD/GMP synthase Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 PRINTS PR00096 Glutamine amidotransferase superfamily signature 162 175 1.2E-6 T 23-10-2018 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 1.2E-6 T 23-10-2018 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 1.2E-6 T 23-10-2018 Mlab_1133 964cc0e6e1f5ae6441990567e4ee2502 508 SUPERFAMILY SSF52317 3 222 1.01E-53 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0276 e76c5acb211b6abbbd1e774dbdb3d2c5 212 Pfam PF02581 Thiamine monophosphate synthase 9 186 5.3E-51 T 23-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_0276 e76c5acb211b6abbbd1e774dbdb3d2c5 212 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 6 206 21.892 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_0276 e76c5acb211b6abbbd1e774dbdb3d2c5 212 SUPERFAMILY SSF51391 7 206 2.49E-54 T 23-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_0276 e76c5acb211b6abbbd1e774dbdb3d2c5 212 Gene3D G3DSA:3.20.20.70 1 209 2.9E-56 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0276 e76c5acb211b6abbbd1e774dbdb3d2c5 212 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 8 199 4.5E-51 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_1730 0f49256ea7aa8ac65e8205846845e29f 143 Gene3D G3DSA:2.60.40.10 31 135 1.4E-7 T 23-10-2018 IPR013783 Immunoglobulin-like fold Mlab_0564 7499f6b61b759e7d046649e3b8ceb162 80 Pfam PF09880 Predicted membrane protein (DUF2107) 7 78 7.7E-31 T 23-10-2018 IPR011317 Predicted [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaE Mlab_0010 ce0dfc9d4139517ae2d5dafc86adb152 270 Pfam PF13411 MerR HTH family regulatory protein 2 69 1.5E-16 T 23-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Mlab_0010 ce0dfc9d4139517ae2d5dafc86adb152 270 Gene3D G3DSA:1.10.1660.10 1 106 1.1E-24 T 23-10-2018 Mlab_0010 ce0dfc9d4139517ae2d5dafc86adb152 270 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 1.5E-5 T 23-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Mlab_0010 ce0dfc9d4139517ae2d5dafc86adb152 270 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 1.5E-5 T 23-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Mlab_0010 ce0dfc9d4139517ae2d5dafc86adb152 270 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 1.5E-5 T 23-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Mlab_0010 ce0dfc9d4139517ae2d5dafc86adb152 270 SMART SM00422 2 71 2.5E-19 T 23-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Mlab_0010 ce0dfc9d4139517ae2d5dafc86adb152 270 Pfam PF06445 GyrI-like small molecule binding domain 116 265 1.3E-13 T 23-10-2018 IPR029442 GyrI-like small molecule binding domain Mlab_0010 ce0dfc9d4139517ae2d5dafc86adb152 270 Gene3D G3DSA:3.20.80.10 108 267 8.8E-23 T 23-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily Mlab_0010 ce0dfc9d4139517ae2d5dafc86adb152 270 SUPERFAMILY SSF55136 159 266 5.93E-20 T 23-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily Mlab_0010 ce0dfc9d4139517ae2d5dafc86adb152 270 SMART SM00871 113 266 2.7E-20 T 23-10-2018 IPR010499 Bacterial transcription activator, effector binding Mlab_0010 ce0dfc9d4139517ae2d5dafc86adb152 270 SUPERFAMILY SSF46955 2 112 1.03E-22 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily Mlab_0486 c7c67a13dc36d72110044d485713b0db 177 Gene3D G3DSA:3.40.920.10 1 177 5.2E-50 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Mlab_0486 c7c67a13dc36d72110044d485713b0db 177 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 169 1.6E-28 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Mlab_0486 c7c67a13dc36d72110044d485713b0db 177 SUPERFAMILY SSF53323 3 174 6.67E-38 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Mlab_1661 ed9cbcc25c0194efa0a4e3f7e68e4e24 533 SUPERFAMILY SSF50249 67 189 5.43E-23 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_1661 ed9cbcc25c0194efa0a4e3f7e68e4e24 533 SUPERFAMILY SSF50249 171 269 6.0E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_1661 ed9cbcc25c0194efa0a4e3f7e68e4e24 533 Gene3D G3DSA:2.40.50.140 74 170 2.5E-19 T 23-10-2018 Mlab_1661 ed9cbcc25c0194efa0a4e3f7e68e4e24 533 Gene3D G3DSA:2.40.50.140 282 380 2.7E-20 T 23-10-2018 Mlab_1661 ed9cbcc25c0194efa0a4e3f7e68e4e24 533 Gene3D G3DSA:2.40.50.140 174 273 3.7E-17 T 23-10-2018 Mlab_1661 ed9cbcc25c0194efa0a4e3f7e68e4e24 533 SUPERFAMILY SSF50249 280 380 6.28E-21 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_1661 ed9cbcc25c0194efa0a4e3f7e68e4e24 533 SUPERFAMILY SSF50249 385 519 2.23E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0983 6c6f67ebba036ca1086516f56d591f0d 550 SUPERFAMILY SSF159245 107 491 1.96E-44 T 23-10-2018 Mlab_0983 6c6f67ebba036ca1086516f56d591f0d 550 Pfam PF07143 CrtC N-terminal lipocalin domain 132 316 1.0E-18 T 23-10-2018 IPR010791 AttH domain Mlab_0983 6c6f67ebba036ca1086516f56d591f0d 550 Gene3D G3DSA:2.40.370.10 118 320 8.3E-25 T 23-10-2018 IPR023374 AttH-like domain superfamily Mlab_0983 6c6f67ebba036ca1086516f56d591f0d 550 Pfam PF17186 Lipocalin-like domain 339 487 8.0E-7 T 23-10-2018 Mlab_0983 6c6f67ebba036ca1086516f56d591f0d 550 Gene3D G3DSA:2.40.370.10 338 496 1.4E-7 T 23-10-2018 IPR023374 AttH-like domain superfamily Mlab_1397 9fa0220f132c856f2e48913f1bf6884e 340 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 65 5.7E-19 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_1397 9fa0220f132c856f2e48913f1bf6884e 340 Pfam PF00591 Glycosyl transferase family, a/b domain 75 323 5.5E-96 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_1397 9fa0220f132c856f2e48913f1bf6884e 340 Gene3D G3DSA:3.40.1030.10 73 337 7.8E-108 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_1397 9fa0220f132c856f2e48913f1bf6884e 340 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 6 331 5.0E-124 T 23-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 Mlab_1397 9fa0220f132c856f2e48913f1bf6884e 340 SUPERFAMILY SSF47648 2 68 5.63E-18 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_1397 9fa0220f132c856f2e48913f1bf6884e 340 Gene3D G3DSA:1.20.970.10 1 69 5.8E-24 T 23-10-2018 Mlab_1397 9fa0220f132c856f2e48913f1bf6884e 340 SUPERFAMILY SSF52418 74 336 7.72E-97 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_1397 9fa0220f132c856f2e48913f1bf6884e 340 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 333 38.092 T 23-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 Mlab_0415 f4bae344836c2065335c7bc29bfeb30e 410 Gene3D G3DSA:3.40.50.800 318 408 6.0E-19 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily Mlab_0415 f4bae344836c2065335c7bc29bfeb30e 410 SUPERFAMILY SSF55681 1 312 3.58E-73 T 23-10-2018 Mlab_0415 f4bae344836c2065335c7bc29bfeb30e 410 Pfam PF03129 Anticodon binding domain 332 405 9.3E-12 T 23-10-2018 IPR004154 Anticodon-binding Mlab_0415 f4bae344836c2065335c7bc29bfeb30e 410 SUPERFAMILY SSF52954 317 406 1.19E-18 T 23-10-2018 Mlab_0415 f4bae344836c2065335c7bc29bfeb30e 410 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 3 397 1.4E-111 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 Mlab_0415 f4bae344836c2065335c7bc29bfeb30e 410 Pfam PF13393 Histidyl-tRNA synthetase 7 304 2.7E-52 T 23-10-2018 Mlab_0415 f4bae344836c2065335c7bc29bfeb30e 410 Gene3D G3DSA:3.30.930.10 1 315 9.3E-90 T 23-10-2018 Mlab_0415 f4bae344836c2065335c7bc29bfeb30e 410 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 407 26.944 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 Mlab_0415 f4bae344836c2065335c7bc29bfeb30e 410 PIRSF PIRSF001549 1 409 3.0E-108 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Mlab_1724 714c51da4a324d6521574404571d20dd 386 SUPERFAMILY SSF53254 197 368 1.83E-16 T 23-10-2018 IPR029033 Histidine phosphatase superfamily Mlab_1724 714c51da4a324d6521574404571d20dd 386 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 197 363 7.1E-9 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Mlab_1724 714c51da4a324d6521574404571d20dd 386 Gene3D G3DSA:3.40.50.1240 188 372 3.6E-12 T 23-10-2018 IPR029033 Histidine phosphatase superfamily Mlab_1579 0d7dd2ceb3596c91e74fd11faee0a929 103 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 100 13.436 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1579 0d7dd2ceb3596c91e74fd11faee0a929 103 Pfam PF00428 60s Acidic ribosomal protein 17 102 2.2E-18 T 23-10-2018 Mlab_1579 0d7dd2ceb3596c91e74fd11faee0a929 103 Gene3D G3DSA:1.10.10.1410 1 58 2.0E-25 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1579 0d7dd2ceb3596c91e74fd11faee0a929 103 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 103 8.6E-39 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 Mlab_0066 6bd82cf8675e3b5f3eae458bb7299327 442 Gene3D G3DSA:3.30.565.60 198 359 6.4E-30 T 23-10-2018 IPR038475 RecG, C-terminal domain superfamily Mlab_0066 6bd82cf8675e3b5f3eae458bb7299327 442 Pfam PF13412 Winged helix-turn-helix DNA-binding 384 427 1.4E-8 T 23-10-2018 Mlab_0066 6bd82cf8675e3b5f3eae458bb7299327 442 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 278 342 2.3E-15 T 23-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain Mlab_0066 6bd82cf8675e3b5f3eae458bb7299327 442 Gene3D G3DSA:1.10.10.10 384 440 1.4E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0066 6bd82cf8675e3b5f3eae458bb7299327 442 SUPERFAMILY SSF46785 377 433 4.73E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0066 6bd82cf8675e3b5f3eae458bb7299327 442 Pfam PF04326 Putative DNA-binding domain 4 123 3.4E-17 T 23-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 Mlab_0066 6bd82cf8675e3b5f3eae458bb7299327 442 Gene3D G3DSA:3.30.950.30 1 130 7.3E-22 T 23-10-2018 IPR038461 Schlafen, AAA domain superfamily Mlab_1741 2ced77c1409228616de2b03c4acc3f69 243 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 75 219 6.4E-29 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Mlab_1741 2ced77c1409228616de2b03c4acc3f69 243 Gene3D G3DSA:3.40.1390.30 75 212 1.8E-24 T 23-10-2018 Mlab_1741 2ced77c1409228616de2b03c4acc3f69 243 SUPERFAMILY SSF102705 1 220 2.88E-37 T 23-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily Mlab_1741 2ced77c1409228616de2b03c4acc3f69 243 Gene3D G3DSA:3.40.1390.30 80 202 1.8E-24 T 23-10-2018 Mlab_1308 2ece0533034f5e33dae4e7a2fb31d56f 360 PIRSF PIRSF000112 15 357 1.8E-59 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 Mlab_1308 2ece0533034f5e33dae4e7a2fb31d56f 360 Pfam PF13685 Iron-containing alcohol dehydrogenase 29 283 1.5E-62 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 Mlab_1308 2ece0533034f5e33dae4e7a2fb31d56f 360 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 19 360 42.17 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 Mlab_1308 2ece0533034f5e33dae4e7a2fb31d56f 360 Gene3D G3DSA:1.20.1090.10 171 358 5.0E-57 T 23-10-2018 Mlab_1308 2ece0533034f5e33dae4e7a2fb31d56f 360 Gene3D G3DSA:3.40.50.1970 17 170 2.7E-31 T 23-10-2018 Mlab_1308 2ece0533034f5e33dae4e7a2fb31d56f 360 SUPERFAMILY SSF56796 17 341 1.7E-66 T 23-10-2018 Mlab_0095 882289bcdc9005e93ca6516577cdc602 56 SUPERFAMILY SSF57716 10 54 2.71E-6 T 23-10-2018 Mlab_0095 882289bcdc9005e93ca6516577cdc602 56 Pfam PF00253 Ribosomal protein S14p/S29e 11 54 4.0E-13 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0095 882289bcdc9005e93ca6516577cdc602 56 Gene3D G3DSA:4.10.830.10 7 56 7.0E-21 T 23-10-2018 Mlab_0095 882289bcdc9005e93ca6516577cdc602 56 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 3 56 17.047 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 Mlab_0993 28d77b34d369394323e1f1b23fb363c1 200 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 12 200 2.0E-63 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 Mlab_0993 28d77b34d369394323e1f1b23fb363c1 200 Gene3D G3DSA:3.40.50.10490 5 200 8.8E-54 T 23-10-2018 Mlab_0993 28d77b34d369394323e1f1b23fb363c1 200 SUPERFAMILY SSF53697 9 199 5.64E-36 T 23-10-2018 Mlab_0993 28d77b34d369394323e1f1b23fb363c1 200 Pfam PF01380 SIS domain 39 137 1.6E-15 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Mlab_1239 46bc44ba99dc35bb92269cf39371f5c4 62 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 4 18 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1239 46bc44ba99dc35bb92269cf39371f5c4 62 Gene3D G3DSA:3.90.940.50 1 54 1.1E-24 T 23-10-2018 Mlab_1239 46bc44ba99dc35bb92269cf39371f5c4 62 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 1 55 19.468 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1239 46bc44ba99dc35bb92269cf39371f5c4 62 SUPERFAMILY SSF63562 2 55 1.96E-20 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1239 46bc44ba99dc35bb92269cf39371f5c4 62 SMART SM01409 1 49 3.5E-5 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1239 46bc44ba99dc35bb92269cf39371f5c4 62 PIRSF PIRSF000778 1 61 4.2E-25 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1239 46bc44ba99dc35bb92269cf39371f5c4 62 Pfam PF01192 RNA polymerase Rpb6 3 49 8.6E-14 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1126 6bbd7c8b9297b26d09df697cdae6d9f4 212 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Mlab_1126 6bbd7c8b9297b26d09df697cdae6d9f4 212 Gene3D G3DSA:1.20.120.1760 7 209 2.1E-46 T 23-10-2018 Mlab_1126 6bbd7c8b9297b26d09df697cdae6d9f4 212 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 90 2.3E-12 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Mlab_0193 3538fd9d1862946208bdb4ae8b04c15c 413 Pfam PF02687 FtsX-like permease family 314 406 3.3E-12 T 23-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Mlab_0193 3538fd9d1862946208bdb4ae8b04c15c 413 Pfam PF12704 MacB-like periplasmic core domain 32 249 1.1E-23 T 23-10-2018 IPR025857 MacB-like periplasmic core domain Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 PRINTS PR00097 Anthranilate synthase component II signature 329 342 8.1E-5 T 23-10-2018 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 PRINTS PR00097 Anthranilate synthase component II signature 218 227 8.1E-5 T 23-10-2018 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 PRINTS PR00097 Anthranilate synthase component II signature 245 256 8.1E-5 T 23-10-2018 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 SUPERFAMILY SSF52317 155 338 4.78E-42 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 245 261 1.2E-20 T 23-10-2018 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 176 190 1.2E-20 T 23-10-2018 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 286 297 1.2E-20 T 23-10-2018 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 262 279 1.2E-20 T 23-10-2018 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 215 229 1.2E-20 T 23-10-2018 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 8 336 1.3E-93 T 23-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 245 256 2.3E-6 T 23-10-2018 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 329 342 2.3E-6 T 23-10-2018 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 218 227 2.3E-6 T 23-10-2018 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 Gene3D G3DSA:3.50.30.20 5 150 8.7E-42 T 23-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 Pfam PF00117 Glutamine amidotransferase class-I 179 336 1.6E-28 T 23-10-2018 IPR017926 Glutamine amidotransferase Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 SMART SM01097 6 133 4.2E-59 T 23-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 SUPERFAMILY SSF52021 6 147 9.29E-41 T 23-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 Gene3D G3DSA:3.40.50.880 151 344 1.7E-43 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0282 88d09e84af7ccdda9b25aa119b75f3f2 358 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 7 131 1.3E-36 T 23-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_1437 149d036254d857ff0873426c9fbd441d 228 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 110 2.0E-20 T 23-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 Mlab_1437 149d036254d857ff0873426c9fbd441d 228 SUPERFAMILY SSF161098 13 201 3.4E-38 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1437 149d036254d857ff0873426c9fbd441d 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 216 7.4E-21 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_1437 149d036254d857ff0873426c9fbd441d 228 Gene3D G3DSA:1.10.3720.10 5 217 1.8E-47 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0295 0a7cbae3758f4bb1dc6e35bc6df8a1d0 115 Gene3D G3DSA:1.10.10.10 14 112 9.2E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0295 0a7cbae3758f4bb1dc6e35bc6df8a1d0 115 SUPERFAMILY SSF46785 17 105 2.54E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0295 0a7cbae3758f4bb1dc6e35bc6df8a1d0 115 Pfam PF03551 Transcriptional regulator PadR-like family 31 93 4.9E-13 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 Pfam PF10996 Beta-Casp domain 425 549 5.6E-23 T 23-10-2018 IPR022712 Beta-Casp domain Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 SUPERFAMILY SSF56281 182 634 1.02E-125 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 Gene3D G3DSA:3.30.300.230 13 169 5.3E-59 T 23-10-2018 Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 SMART SM00849 195 393 2.6E-23 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 Pfam PF00753 Metallo-beta-lactamase superfamily 197 392 3.0E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 8 635 4.7E-299 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 Pfam PF17214 KH domain 4 67 4.3E-26 T 23-10-2018 IPR033769 KH domain, archaeal Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 SUPERFAMILY SSF54814 91 129 6.54E-5 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 563 627 9.5E-16 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 SMART SM00322 95 162 9.0E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 SMART SM01027 424 549 8.2E-54 T 23-10-2018 IPR022712 Beta-Casp domain Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 Gene3D G3DSA:3.40.50.10890 392 576 7.7E-144 T 23-10-2018 Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 Gene3D G3DSA:3.30.300.20 67 135 5.3E-59 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta Mlab_1014 b1a416fa9c2a8350a4375e303409140e 636 Gene3D G3DSA:3.60.15.10 188 609 7.7E-144 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 258 1.1E-62 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 SUPERFAMILY SSF54980 389 464 1.87E-20 T 23-10-2018 IPR035647 EF-G domain III/V-like Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 SUPERFAMILY SSF52540 9 262 2.15E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 Gene3D G3DSA:3.40.50.300 7 223 2.4E-73 T 23-10-2018 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 154 2.0E-22 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 Gene3D G3DSA:3.30.70.240 469 720 1.8E-76 T 23-10-2018 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 SMART SM00889 511 621 5.5E-21 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 SUPERFAMILY SSF50447 260 385 1.81E-29 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 727 39.299 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 2.0E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 2.0E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 2.0E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 2.0E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 2.0E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 SMART SM00838 623 710 2.2E-43 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 Gene3D G3DSA:2.40.30.10 260 389 2.7E-22 T 23-10-2018 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 5 721 0.0 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 Pfam PF14492 Elongation Factor G, domain II 390 462 1.2E-23 T 23-10-2018 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 Gene3D G3DSA:3.30.230.10 475 724 1.8E-76 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 Pfam PF03764 Elongation factor G, domain IV 525 620 2.2E-23 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 SUPERFAMILY SSF54211 466 625 3.54E-45 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 Pfam PF03144 Elongation factor Tu domain 2 307 375 2.5E-15 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 Pfam PF00679 Elongation factor G C-terminus 624 708 1.0E-23 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 Gene3D G3DSA:3.30.70.870 391 467 5.5E-25 T 23-10-2018 Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site Mlab_1613 bb89019cc52a9606de11f25457ad188a 732 SUPERFAMILY SSF54980 626 720 5.76E-23 T 23-10-2018 IPR035647 EF-G domain III/V-like Mlab_1557 98a6a592d24d9c5eb47addc9895f91bb 98 PIRSF PIRSF005518 1 96 2.1E-19 T 23-10-2018 IPR008690 Tetrahydromethanopterin S-methyltransferase subunit B GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1557 98a6a592d24d9c5eb47addc9895f91bb 98 ProDom PD012565 METHYLTRANSFERASE SUBUNIT B M TETRAHYDROMETHANOPTERIN S-METHYLTRANSFERASE MEMBRANE N5-METHYLTETRAHYDROMETHANOPTERIN--COENZYME METHANOGENESIS TRANSFERASE 1 77 1.0E-17 T 23-10-2018 IPR008690 Tetrahydromethanopterin S-methyltransferase subunit B GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1557 98a6a592d24d9c5eb47addc9895f91bb 98 Hamap MF_01094 Tetrahydromethanopterin S-methyltransferase subunit B [mtrB]. 1 91 21.145 T 23-10-2018 IPR008690 Tetrahydromethanopterin S-methyltransferase subunit B GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1557 98a6a592d24d9c5eb47addc9895f91bb 98 TIGRFAM TIGR04166 methano_MtrB: tetrahydromethanopterin S-methyltransferase, subunit B 3 91 4.4E-26 T 23-10-2018 IPR008690 Tetrahydromethanopterin S-methyltransferase subunit B GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1557 98a6a592d24d9c5eb47addc9895f91bb 98 Pfam PF05440 Tetrahydromethanopterin S-methyltransferase subunit B 3 91 3.0E-31 T 23-10-2018 IPR008690 Tetrahydromethanopterin S-methyltransferase subunit B GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_0200 38c87bf4f4a6939701c15ce79c6e863c 421 Pfam PF01964 Radical SAM ThiC family 16 414 8.5E-159 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Mlab_0200 38c87bf4f4a6939701c15ce79c6e863c 421 Gene3D G3DSA:3.20.20.540 43 357 1.6E-123 T 23-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Mlab_0200 38c87bf4f4a6939701c15ce79c6e863c 421 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 17 416 9.8E-152 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Mlab_0022 3697514b1474cec4288ed41686ddb9ba 225 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 107 6.3E-14 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Mlab_0022 3697514b1474cec4288ed41686ddb9ba 225 Gene3D G3DSA:3.40.50.720 4 225 2.9E-44 T 23-10-2018 Mlab_0022 3697514b1474cec4288ed41686ddb9ba 225 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 5 223 8.3E-56 T 23-10-2018 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 Mlab_0022 3697514b1474cec4288ed41686ddb9ba 225 SUPERFAMILY SSF51735 4 220 1.67E-35 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0143 98b57d7ffaf17dae1bf9c967eef3cf79 331 SUPERFAMILY SSF55326 5 163 3.49E-32 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0143 98b57d7ffaf17dae1bf9c967eef3cf79 331 Pfam PF02769 AIR synthase related protein, C-terminal domain 171 325 2.7E-21 T 23-10-2018 IPR010918 PurM-like, C-terminal domain Mlab_0143 98b57d7ffaf17dae1bf9c967eef3cf79 331 SUPERFAMILY SSF56042 165 323 1.94E-40 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0143 98b57d7ffaf17dae1bf9c967eef3cf79 331 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 6 318 4.8E-101 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Mlab_0143 98b57d7ffaf17dae1bf9c967eef3cf79 331 Pfam PF00586 AIR synthase related protein, N-terminal domain 58 157 5.7E-10 T 23-10-2018 IPR016188 PurM-like, N-terminal domain Mlab_0143 98b57d7ffaf17dae1bf9c967eef3cf79 331 Gene3D G3DSA:3.90.650.10 165 331 1.9E-49 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0143 98b57d7ffaf17dae1bf9c967eef3cf79 331 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 5 328 34.252 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Mlab_0143 98b57d7ffaf17dae1bf9c967eef3cf79 331 Gene3D G3DSA:3.30.1330.10 4 164 1.3E-41 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_1669 b52652325c0ae7811e75ad8d475de41e 659 Pfam PF07694 5TMR of 5TMR-LYT 457 625 1.5E-42 T 23-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 Mlab_1669 b52652325c0ae7811e75ad8d475de41e 659 Gene3D G3DSA:1.10.1760.20 482 627 4.2E-6 T 23-10-2018 Mlab_1669 b52652325c0ae7811e75ad8d475de41e 659 Pfam PF01566 Natural resistance-associated macrophage protein 37 268 3.9E-13 T 23-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 Gene3D G3DSA:3.40.50.1260 12 395 6.2E-118 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 1.3E-65 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 PRINTS PR00477 Phosphoglycerate kinase family signature 319 344 1.3E-65 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.3E-65 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 1.3E-65 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 PRINTS PR00477 Phosphoglycerate kinase family signature 33 55 1.3E-65 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 PRINTS PR00477 Phosphoglycerate kinase family signature 351 362 1.3E-65 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 PRINTS PR00477 Phosphoglycerate kinase family signature 374 391 1.3E-65 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 PRINTS PR00477 Phosphoglycerate kinase family signature 107 122 1.3E-65 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 1.3E-65 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 PIRSF PIRSF000724 1 405 3.1E-130 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 Gene3D G3DSA:3.40.50.1260 191 388 6.2E-118 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 23-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 Pfam PF00162 Phosphoglycerate kinase 7 388 1.9E-109 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 398 34.198 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1251 4e7f4132433efb599ff062b1ccbf455a 405 SUPERFAMILY SSF53748 1 398 1.18E-111 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_0033 ca2a2e5b94c115ebc3df9fd9f15ce92f 743 Gene3D G3DSA:3.40.50.300 1 218 6.3E-6 T 23-10-2018 Mlab_0033 ca2a2e5b94c115ebc3df9fd9f15ce92f 743 Gene3D G3DSA:3.40.50.300 236 611 1.2E-12 T 23-10-2018 Mlab_0033 ca2a2e5b94c115ebc3df9fd9f15ce92f 743 SUPERFAMILY SSF52540 1 588 4.62E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0033 ca2a2e5b94c115ebc3df9fd9f15ce92f 743 Pfam PF13166 AAA domain 13 712 1.7E-206 T 23-10-2018 IPR026866 Protein CR006, P-loop domain Mlab_1678 526bb16f69764c3476c2b7f22e624a3e 355 SUPERFAMILY SSF103481 70 149 3.4E-11 T 23-10-2018 Mlab_1678 526bb16f69764c3476c2b7f22e624a3e 355 SUPERFAMILY SSF103481 197 294 4.97E-10 T 23-10-2018 Mlab_1678 526bb16f69764c3476c2b7f22e624a3e 355 Pfam PF00892 EamA-like transporter family 158 286 6.5E-12 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Mlab_1678 526bb16f69764c3476c2b7f22e624a3e 355 Pfam PF00892 EamA-like transporter family 9 146 8.0E-21 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 113 128 4.3E-27 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 130 148 4.3E-27 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 65 85 4.3E-27 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 86 104 4.3E-27 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 Pfam PF01926 50S ribosome-binding GTPase 65 152 9.2E-20 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 Gene3D G3DSA:3.40.50.300 192 293 4.6E-9 T 23-10-2018 Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 Gene3D G3DSA:3.40.50.300 51 181 1.8E-31 T 23-10-2018 Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 Gene3D G3DSA:3.10.20.30 294 369 9.4E-32 T 23-10-2018 IPR012675 Beta-grasp domain superfamily Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 SUPERFAMILY SSF81271 289 368 6.32E-18 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 SUPERFAMILY SSF52540 64 305 4.12E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 Pfam PF16897 C-terminal region of MMR_HSR1 domain 184 293 4.3E-26 T 23-10-2018 IPR031662 GTP binding protein, second domain Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 62 177 1.0E-21 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Mlab_1400 86d84905a0a25f8d4c007354b197904c 370 Pfam PF02824 TGS domain 295 368 2.6E-20 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 Mlab_0622 9a710c283b934c0c499ddfe1f923c916 483 Gene3D G3DSA:1.20.1740.10 63 451 5.3E-6 T 23-10-2018 Mlab_0622 9a710c283b934c0c499ddfe1f923c916 483 Pfam PF01235 Sodium:alanine symporter family 63 463 1.7E-141 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Mlab_0622 9a710c283b934c0c499ddfe1f923c916 483 PRINTS PR00175 Sodium/alanine symporter signature 359 381 1.5E-44 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Mlab_0622 9a710c283b934c0c499ddfe1f923c916 483 PRINTS PR00175 Sodium/alanine symporter signature 98 120 1.5E-44 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Mlab_0622 9a710c283b934c0c499ddfe1f923c916 483 PRINTS PR00175 Sodium/alanine symporter signature 189 207 1.5E-44 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Mlab_0622 9a710c283b934c0c499ddfe1f923c916 483 PRINTS PR00175 Sodium/alanine symporter signature 217 236 1.5E-44 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Mlab_0622 9a710c283b934c0c499ddfe1f923c916 483 PRINTS PR00175 Sodium/alanine symporter signature 419 439 1.5E-44 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Mlab_0622 9a710c283b934c0c499ddfe1f923c916 483 PRINTS PR00175 Sodium/alanine symporter signature 308 326 1.5E-44 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Mlab_0622 9a710c283b934c0c499ddfe1f923c916 483 TIGRFAM TIGR00835 agcS: amino acid carrier protein 23 450 1.5E-132 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Mlab_0622 9a710c283b934c0c499ddfe1f923c916 483 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 98 113 - T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Mlab_0909 8c0e1f51ac5f6f624b10b54b3942770e 328 Pfam PF02661 Fic/DOC family 94 191 2.7E-26 T 23-10-2018 IPR003812 Fido domain Mlab_0909 8c0e1f51ac5f6f624b10b54b3942770e 328 SUPERFAMILY SSF46785 272 323 2.56E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0909 8c0e1f51ac5f6f624b10b54b3942770e 328 Pfam PF13412 Winged helix-turn-helix DNA-binding 273 313 3.8E-7 T 23-10-2018 Mlab_0909 8c0e1f51ac5f6f624b10b54b3942770e 328 Gene3D G3DSA:1.10.10.10 264 328 1.0E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0909 8c0e1f51ac5f6f624b10b54b3942770e 328 SUPERFAMILY SSF140931 70 246 1.57E-43 T 23-10-2018 IPR036597 Fido-like domain superfamily Mlab_0909 8c0e1f51ac5f6f624b10b54b3942770e 328 Gene3D G3DSA:1.10.3290.10 4 249 5.9E-74 T 23-10-2018 IPR036597 Fido-like domain superfamily Mlab_0170 df39896de040454587bf4bcc0631d1a0 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 290 6.4E-19 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_0170 df39896de040454587bf4bcc0631d1a0 301 Gene3D G3DSA:1.10.3720.10 86 297 2.9E-19 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0170 df39896de040454587bf4bcc0631d1a0 301 SUPERFAMILY SSF161098 91 280 6.76E-22 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1384 39627f00277cb811cc33d77c59843e98 104 SUPERFAMILY SSF101386 6 97 1.18E-18 T 23-10-2018 Mlab_1384 39627f00277cb811cc33d77c59843e98 104 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 39 95 1.3E-11 T 23-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 Mlab_1384 39627f00277cb811cc33d77c59843e98 104 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 4 93 17.393 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 Mlab_1384 39627f00277cb811cc33d77c59843e98 104 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 8 93 1.0E-24 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 Mlab_1384 39627f00277cb811cc33d77c59843e98 104 Gene3D G3DSA:1.10.287.1080 3 99 7.9E-25 T 23-10-2018 Mlab_0744 14df2699bad77730a2d653a799d29d0e 61 SUPERFAMILY SSF47598 1 43 3.71E-10 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Mlab_0744 14df2699bad77730a2d653a799d29d0e 61 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 40 2.1E-8 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Mlab_1172 47b4f83a3cfd396b68ed3e909d6124d7 221 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 208 8.0E-60 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1172 47b4f83a3cfd396b68ed3e909d6124d7 221 ProSitePatterns PS00171 Triosephosphate isomerase active site. 138 148 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1172 47b4f83a3cfd396b68ed3e909d6124d7 221 Gene3D G3DSA:3.20.20.70 1 221 8.1E-74 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1172 47b4f83a3cfd396b68ed3e909d6124d7 221 Pfam PF05690 Thiazole biosynthesis protein ThiG 171 213 3.7E-5 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 Mlab_1172 47b4f83a3cfd396b68ed3e909d6124d7 221 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 3 221 39.805 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 Mlab_1172 47b4f83a3cfd396b68ed3e909d6124d7 221 Pfam PF00121 Triosephosphate isomerase 5 120 2.1E-10 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1172 47b4f83a3cfd396b68ed3e909d6124d7 221 SUPERFAMILY SSF51351 1 219 2.36E-42 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1693 85647d42ec9213cbceca06b266750db8 533 Pfam PF07969 Amidohydrolase family 54 524 7.3E-88 T 23-10-2018 IPR013108 Amidohydrolase 3 Mlab_1693 85647d42ec9213cbceca06b266750db8 533 Gene3D G3DSA:3.10.310.70 84 200 3.6E-96 T 23-10-2018 Mlab_1693 85647d42ec9213cbceca06b266750db8 533 Gene3D G3DSA:3.20.20.140 65 488 3.6E-96 T 23-10-2018 Mlab_1693 85647d42ec9213cbceca06b266750db8 533 SUPERFAMILY SSF51556 64 488 3.89E-28 T 23-10-2018 IPR032466 Metal-dependent hydrolase Mlab_1693 85647d42ec9213cbceca06b266750db8 533 SUPERFAMILY SSF51338 10 525 1.57E-14 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_1693 85647d42ec9213cbceca06b266750db8 533 Gene3D G3DSA:2.30.40.10 15 502 3.6E-96 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 96 102 - T 23-10-2018 IPR014762 DNA mismatch repair, conserved site Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 SMART SM01340 213 332 2.8E-47 T 23-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 SUPERFAMILY SSF118116 404 587 1.44E-42 T 23-10-2018 IPR037198 MutL, C-terminal domain superfamily Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 Gene3D G3DSA:3.30.1370.100 446 542 2.4E-51 T 23-10-2018 Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 SUPERFAMILY SSF54211 196 331 6.83E-32 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 213 331 1.8E-33 T 23-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 125 2.4E-13 T 23-10-2018 Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 SUPERFAMILY SSF55874 3 218 3.27E-49 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 312 4.2E-85 T 23-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 Gene3D G3DSA:3.30.565.10 3 208 4.7E-57 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 SMART SM00853 404 545 3.4E-39 T 23-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 Gene3D G3DSA:2.30.42.20 405 587 2.4E-51 T 23-10-2018 Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 Pfam PF08676 MutL C terminal dimerisation domain 403 545 2.0E-30 T 23-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 585 22.862 T 23-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 Mlab_1168 6fa0be418c0dac803b24452f3d6fe312 588 Gene3D G3DSA:3.30.230.10 218 331 3.3E-30 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Mlab_1304 c1c244639fcc98f1bb7f5430ac6fa9d6 520 SUPERFAMILY SSF55729 406 517 7.4E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_1304 c1c244639fcc98f1bb7f5430ac6fa9d6 520 SMART SM00729 73 334 6.4E-36 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_1304 c1c244639fcc98f1bb7f5430ac6fa9d6 520 Pfam PF04055 Radical SAM superfamily 82 277 3.0E-18 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_1304 c1c244639fcc98f1bb7f5430ac6fa9d6 520 Pfam PF00583 Acetyltransferase (GNAT) family 411 509 1.2E-4 T 23-10-2018 IPR000182 GNAT domain Mlab_1304 c1c244639fcc98f1bb7f5430ac6fa9d6 520 Gene3D G3DSA:3.80.30.20 184 346 1.3E-10 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Mlab_1304 c1c244639fcc98f1bb7f5430ac6fa9d6 520 Gene3D G3DSA:3.40.630.30 382 520 7.7E-10 T 23-10-2018 Mlab_1304 c1c244639fcc98f1bb7f5430ac6fa9d6 520 Pfam PF16199 Radical_SAM C-terminal domain 295 375 7.7E-25 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 Mlab_1304 c1c244639fcc98f1bb7f5430ac6fa9d6 520 PIRSF PIRSF005669 4 520 2.0E-203 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 Mlab_1304 c1c244639fcc98f1bb7f5430ac6fa9d6 520 SUPERFAMILY SSF102114 135 342 4.97E-27 T 23-10-2018 Mlab_1304 c1c244639fcc98f1bb7f5430ac6fa9d6 520 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 20 520 1.0E-201 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 Mlab_1054 5bb455956fddf86db642dd98d0cb3da1 434 Pfam PF01979 Amidohydrolase family 58 403 1.9E-72 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Mlab_1054 5bb455956fddf86db642dd98d0cb3da1 434 Gene3D G3DSA:3.20.20.140 61 351 1.1E-127 T 23-10-2018 Mlab_1054 5bb455956fddf86db642dd98d0cb3da1 434 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 12 428 41.21 T 23-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 Mlab_1054 5bb455956fddf86db642dd98d0cb3da1 434 Gene3D G3DSA:2.30.40.10 33 411 1.1E-127 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_1054 5bb455956fddf86db642dd98d0cb3da1 434 SUPERFAMILY SSF51338 32 422 1.28E-14 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_1054 5bb455956fddf86db642dd98d0cb3da1 434 SUPERFAMILY SSF51556 60 354 2.16E-97 T 23-10-2018 IPR032466 Metal-dependent hydrolase Mlab_0157 e1c2ed6501ae97bf1e75ab3e66eccb5a 399 Pfam PF00909 Ammonium Transporter Family 9 399 1.1E-120 T 23-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 Mlab_0157 e1c2ed6501ae97bf1e75ab3e66eccb5a 399 ProSitePatterns PS01219 Ammonium transporters signature. 159 184 - T 23-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 Mlab_0157 e1c2ed6501ae97bf1e75ab3e66eccb5a 399 SUPERFAMILY SSF111352 3 380 1.07E-112 T 23-10-2018 Mlab_0157 e1c2ed6501ae97bf1e75ab3e66eccb5a 399 TIGRFAM TIGR00836 amt: ammonium transporter 8 399 3.4E-128 T 23-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 Mlab_0157 e1c2ed6501ae97bf1e75ab3e66eccb5a 399 Gene3D G3DSA:1.10.3430.10 3 399 3.7E-135 T 23-10-2018 IPR029020 Ammonium/urea transporter Mlab_1711 bbfa8e05ea6303e25acefbe6519decae 425 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 425 84.589 T 23-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Mlab_1711 bbfa8e05ea6303e25acefbe6519decae 425 Gene3D G3DSA:3.20.20.540 45 361 9.5E-123 T 23-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Mlab_1711 bbfa8e05ea6303e25acefbe6519decae 425 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 1.3E-171 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Mlab_1711 bbfa8e05ea6303e25acefbe6519decae 425 Pfam PF01964 Radical SAM ThiC family 2 420 4.2E-171 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Mlab_0061 0e8a857a431fd259bfa369a8da37ca61 305 Pfam PF03186 CobD/Cbib protein 8 279 1.2E-79 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Mlab_0061 0e8a857a431fd259bfa369a8da37ca61 305 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 5 298 1.5E-64 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Mlab_0061 0e8a857a431fd259bfa369a8da37ca61 305 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 305 71.187 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Mlab_1266 bd463cdd5b02a58e979ee790825402fd 324 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 11 321 1.0E-90 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 Mlab_1266 bd463cdd5b02a58e979ee790825402fd 324 SMART SM00729 24 250 1.3E-21 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_1266 bd463cdd5b02a58e979ee790825402fd 324 SUPERFAMILY SSF102114 17 247 2.09E-13 T 23-10-2018 Mlab_1266 bd463cdd5b02a58e979ee790825402fd 324 PIRSF PIRSF004954 1 322 2.0E-89 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 Mlab_1281 478f72b6add96ca004761c601503e17b 67 Pfam PF02609 Exonuclease VII small subunit 10 60 7.1E-18 T 23-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Mlab_1281 478f72b6add96ca004761c601503e17b 67 SUPERFAMILY SSF116842 2 65 1.44E-16 T 23-10-2018 Mlab_1281 478f72b6add96ca004761c601503e17b 67 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 49 2.0E-7 T 23-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Mlab_1281 478f72b6add96ca004761c601503e17b 67 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 9 67 11.243 T 23-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Mlab_1281 478f72b6add96ca004761c601503e17b 67 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 9 64 3.3E-20 T 23-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Mlab_1281 478f72b6add96ca004761c601503e17b 67 Gene3D G3DSA:1.10.287.1040 3 67 6.3E-14 T 23-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 Mlab_1281 478f72b6add96ca004761c601503e17b 67 PIRSF PIRSF006488 1 67 9.6E-18 T 23-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Mlab_0781 4e7ebbc69d75923601b6f3ea6fa37c07 238 TIGRFAM TIGR03880 KaiC_arch_3: KaiC domain protein, AF_0351 family 14 237 1.6E-90 T 23-10-2018 IPR022420 Circadian clock protein, KaiC, archaea Mlab_0781 4e7ebbc69d75923601b6f3ea6fa37c07 238 Pfam PF06745 KaiC 11 201 1.5E-24 T 23-10-2018 IPR014774 KaiC-like domain Mlab_0781 4e7ebbc69d75923601b6f3ea6fa37c07 238 SUPERFAMILY SSF52540 11 230 1.42E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0781 4e7ebbc69d75923601b6f3ea6fa37c07 238 Gene3D G3DSA:3.40.50.300 3 224 5.3E-29 T 23-10-2018 Mlab_1364 d55eef591ede76178a6f9fb92fbbd0c5 256 Gene3D G3DSA:3.20.20.150 7 256 9.3E-52 T 23-10-2018 Mlab_1364 d55eef591ede76178a6f9fb92fbbd0c5 256 Pfam PF01261 Xylose isomerase-like TIM barrel 21 217 2.5E-26 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Mlab_1364 d55eef591ede76178a6f9fb92fbbd0c5 256 SUPERFAMILY SSF51658 16 255 2.07E-43 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 SUPERFAMILY SSF55920 2 290 1.96E-58 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 SUPERFAMILY SSF46785 199 264 2.04E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 4.5E-14 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 146 158 4.5E-14 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 55 68 4.5E-14 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 80 96 4.5E-14 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 Hamap MF_01975 Methionine aminopeptidase [map]. 6 290 43.302 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 Gene3D G3DSA:1.10.10.10 196 267 1.1E-79 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 Pfam PF00557 Metallopeptidase family M24 10 283 1.9E-39 T 23-10-2018 IPR000994 Peptidase M24 Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 80 96 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 5 290 1.9E-92 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 Mlab_1267 001529c07adc47788789bdcbe76b1d68 291 Gene3D G3DSA:3.90.230.10 11 281 1.1E-79 T 23-10-2018 Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 Pfam PF00571 CBS domain 233 287 1.5E-9 T 23-10-2018 IPR000644 CBS domain Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 Pfam PF00571 CBS domain 158 211 3.8E-10 T 23-10-2018 IPR000644 CBS domain Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 Pfam PF00571 CBS domain 19 68 2.7E-10 T 23-10-2018 IPR000644 CBS domain Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 Pfam PF00571 CBS domain 96 150 1.1E-7 T 23-10-2018 IPR000644 CBS domain Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 Gene3D G3DSA:3.10.580.10 153 288 2.0E-31 T 23-10-2018 Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 SUPERFAMILY SSF54631 13 150 9.67E-27 T 23-10-2018 Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 Gene3D G3DSA:3.10.580.10 13 151 1.7E-34 T 23-10-2018 Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 SMART SM00116 22 71 5.7E-11 T 23-10-2018 IPR000644 CBS domain Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 SMART SM00116 102 150 5.3E-6 T 23-10-2018 IPR000644 CBS domain Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 SMART SM00116 241 288 7.7E-11 T 23-10-2018 IPR000644 CBS domain Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 SMART SM00116 165 212 3.0E-5 T 23-10-2018 IPR000644 CBS domain Mlab_0750 4bb191a0eaf04435fa83dd4f86ecd24a 291 SUPERFAMILY SSF54631 155 289 4.84E-30 T 23-10-2018 Mlab_0932 fa6e670df6fd0c7568d4d18814142236 298 Gene3D G3DSA:3.40.1190.20 4 292 2.3E-74 T 23-10-2018 IPR029056 Ribokinase-like Mlab_0932 fa6e670df6fd0c7568d4d18814142236 298 Pfam PF00294 pfkB family carbohydrate kinase 7 281 1.9E-41 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB Mlab_0932 fa6e670df6fd0c7568d4d18814142236 298 SUPERFAMILY SSF53613 8 283 3.74E-55 T 23-10-2018 IPR029056 Ribokinase-like Mlab_0932 fa6e670df6fd0c7568d4d18814142236 298 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 42 66 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Mlab_0932 fa6e670df6fd0c7568d4d18814142236 298 PRINTS PR00990 Ribokinase signature 37 56 2.4E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Mlab_0932 fa6e670df6fd0c7568d4d18814142236 298 PRINTS PR00990 Ribokinase signature 10 31 2.4E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Mlab_0932 fa6e670df6fd0c7568d4d18814142236 298 PRINTS PR00990 Ribokinase signature 204 215 2.4E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Mlab_0932 fa6e670df6fd0c7568d4d18814142236 298 PRINTS PR00990 Ribokinase signature 168 183 2.4E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Mlab_1273 762604f8abb3b0123b460dfe912093bd 387 Pfam PF01969 Protein of unknown function DUF111 4 375 1.8E-113 T 23-10-2018 IPR002822 Nickel insertion protein Mlab_1273 762604f8abb3b0123b460dfe912093bd 387 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 3 375 2.1E-95 T 23-10-2018 IPR002822 Nickel insertion protein Mlab_1273 762604f8abb3b0123b460dfe912093bd 387 Gene3D G3DSA:3.30.70.1380 230 320 2.2E-21 T 23-10-2018 Mlab_1273 762604f8abb3b0123b460dfe912093bd 387 Gene3D G3DSA:3.10.20.300 324 385 1.4E-10 T 23-10-2018 Mlab_1273 762604f8abb3b0123b460dfe912093bd 387 Hamap MF_01074 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein [larC]. 1 386 32.814 T 23-10-2018 IPR002822 Nickel insertion protein Mlab_1671 b74f9c175c148eaf4612ae3810cebec8 61 Gene3D G3DSA:1.10.3910.10 1 60 1.3E-20 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily Mlab_1671 b74f9c175c148eaf4612ae3810cebec8 61 SUPERFAMILY SSF140683 1 59 4.71E-16 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily Mlab_1671 b74f9c175c148eaf4612ae3810cebec8 61 TIGRFAM TIGR03980 prismane_assoc: hybrid cluster protein-associated redox disulfide domain 3 59 7.4E-24 T 23-10-2018 IPR023883 Conserved hypothetical protein CHP03980, redox-disulphide Mlab_1671 b74f9c175c148eaf4612ae3810cebec8 61 Pfam PF08984 Domain of unknown function (DUF1858) 3 55 6.7E-21 T 23-10-2018 IPR015077 Domain of unknown function DUF1858 Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 Pfam PF00037 4Fe-4S binding domain 118 138 1.1E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 SUPERFAMILY SSF54862 161 361 4.49E-21 T 23-10-2018 Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 Gene3D G3DSA:3.30.70.20 116 187 1.9E-7 T 23-10-2018 Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 PIRSF PIRSF005658 11 401 3.1E-67 T 23-10-2018 Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 266 277 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 Gene3D G3DSA:3.30.70.20 33 105 1.5E-12 T 23-10-2018 Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 Pfam PF13237 4Fe-4S dicluster domain 291 353 1.2E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 SUPERFAMILY SSF54862 34 141 3.41E-19 T 23-10-2018 Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 Pfam PF12838 4Fe-4S dicluster domain 39 88 1.7E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 Pfam PF12838 4Fe-4S dicluster domain 227 280 9.0E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 Gene3D G3DSA:3.30.70.20 200 286 3.7E-10 T 23-10-2018 Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 123 134 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 Pfam PF12800 4Fe-4S binding domain 170 183 0.9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 Gene3D G3DSA:3.30.70.3270 287 401 4.5E-11 T 23-10-2018 Mlab_0398 00cd47922404dc2d656bc32301c0557a 403 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 227 238 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_1676 2d595b0eff0aa0a295cff2cc0d1a7512 200 Gene3D G3DSA:3.40.50.360 2 192 1.8E-42 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1676 2d595b0eff0aa0a295cff2cc0d1a7512 200 Pfam PF03358 NADPH-dependent FMN reductase 4 133 1.6E-24 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Mlab_1676 2d595b0eff0aa0a295cff2cc0d1a7512 200 SUPERFAMILY SSF52218 1 195 7.92E-41 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0085 a8edbb76aa3539e74900d2593569dd81 136 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 42 125 18.798 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0085 a8edbb76aa3539e74900d2593569dd81 136 SUPERFAMILY SSF54570 61 120 1.96E-20 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0085 a8edbb76aa3539e74900d2593569dd81 136 Gene3D G3DSA:3.30.860.20 2 136 4.0E-39 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0085 a8edbb76aa3539e74900d2593569dd81 136 PRINTS PR00975 Ribosomal protein S19 family signature 101 116 5.9E-12 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0085 a8edbb76aa3539e74900d2593569dd81 136 PRINTS PR00975 Ribosomal protein S19 family signature 89 101 5.9E-12 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0085 a8edbb76aa3539e74900d2593569dd81 136 PRINTS PR00975 Ribosomal protein S19 family signature 69 88 5.9E-12 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0085 a8edbb76aa3539e74900d2593569dd81 136 Pfam PF00203 Ribosomal protein S19 63 119 2.3E-21 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0085 a8edbb76aa3539e74900d2593569dd81 136 PIRSF PIRSF002144 1 136 1.2E-30 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0085 a8edbb76aa3539e74900d2593569dd81 136 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 13 136 1.8E-42 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1181 076198f5068ee296e6d2113b4d9daae8 719 Gene3D G3DSA:3.30.565.10 560 713 1.9E-27 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Mlab_1181 076198f5068ee296e6d2113b4d9daae8 719 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 606 715 2.0E-12 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Mlab_1181 076198f5068ee296e6d2113b4d9daae8 719 SUPERFAMILY SSF55874 570 714 3.86E-24 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Mlab_1181 076198f5068ee296e6d2113b4d9daae8 719 SUPERFAMILY SSF55874 15 187 1.15E-20 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Mlab_1181 076198f5068ee296e6d2113b4d9daae8 719 SMART SM00387 604 716 2.1E-19 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Mlab_1181 076198f5068ee296e6d2113b4d9daae8 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 700 713 5.3E-10 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Mlab_1181 076198f5068ee296e6d2113b4d9daae8 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 646 660 5.3E-10 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Mlab_1181 076198f5068ee296e6d2113b4d9daae8 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 675 693 5.3E-10 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Mlab_1181 076198f5068ee296e6d2113b4d9daae8 719 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 141 8.5E-19 T 23-10-2018 Mlab_1181 076198f5068ee296e6d2113b4d9daae8 719 Gene3D G3DSA:3.30.565.10 11 212 1.4E-27 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Mlab_1181 076198f5068ee296e6d2113b4d9daae8 719 Gene3D G3DSA:1.10.287.130 502 559 1.9E-27 T 23-10-2018 Mlab_1211 eff83d8cc991302f8e9396bfbc928cad 342 Gene3D G3DSA:3.40.50.11740 50 276 7.8E-106 T 23-10-2018 Mlab_1211 eff83d8cc991302f8e9396bfbc928cad 342 Pfam PF01924 Hydrogenase formation hypA family 7 339 1.2E-140 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 Mlab_1211 eff83d8cc991302f8e9396bfbc928cad 342 PIRSF PIRSF005622 2 342 9.0E-140 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 Mlab_1211 eff83d8cc991302f8e9396bfbc928cad 342 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 9 341 2.5E-137 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 Mlab_1211 eff83d8cc991302f8e9396bfbc928cad 342 Gene3D G3DSA:1.10.10.2140 290 341 6.6E-26 T 23-10-2018 Mlab_1211 eff83d8cc991302f8e9396bfbc928cad 342 Gene3D G3DSA:3.40.50.11750 10 236 7.8E-106 T 23-10-2018 Mlab_1614 dca54e0d905b7886d30aff5352bd9c90 194 Gene3D G3DSA:1.10.455.10 1 194 8.4E-68 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily Mlab_1614 dca54e0d905b7886d30aff5352bd9c90 194 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 10 194 38.267 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal Mlab_1614 dca54e0d905b7886d30aff5352bd9c90 194 ProSitePatterns PS00052 Ribosomal protein S7 signature. 60 86 - T 23-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1614 dca54e0d905b7886d30aff5352bd9c90 194 Pfam PF00177 Ribosomal protein S7p/S5e 53 194 6.2E-35 T 23-10-2018 IPR023798 Ribosomal protein S7 domain Mlab_1614 dca54e0d905b7886d30aff5352bd9c90 194 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 10 194 1.9E-71 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1614 dca54e0d905b7886d30aff5352bd9c90 194 PIRSF PIRSF002122 1 194 1.3E-30 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 Mlab_1614 dca54e0d905b7886d30aff5352bd9c90 194 SUPERFAMILY SSF47973 12 194 9.29E-50 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily Mlab_1077 a5a8ebe48ce3728cf7f30e79224442d3 203 Gene3D G3DSA:3.40.1010.10 1 117 1.4E-24 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Mlab_1077 a5a8ebe48ce3728cf7f30e79224442d3 203 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 190 3.3E-35 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Mlab_1077 a5a8ebe48ce3728cf7f30e79224442d3 203 SUPERFAMILY SSF53790 1 199 1.02E-33 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Mlab_1077 a5a8ebe48ce3728cf7f30e79224442d3 203 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 5 19 - T 23-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Mlab_1077 a5a8ebe48ce3728cf7f30e79224442d3 203 PIRSF PIRSF036427 1 203 1.3E-48 T 23-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 Mlab_0393 5d5eda4d8bc9b81df5bbb88c76225ccb 177 Pfam PF13432 Tetratricopeptide repeat 84 140 1.1E-9 T 23-10-2018 Mlab_0393 5d5eda4d8bc9b81df5bbb88c76225ccb 177 SMART SM00028 44 78 29.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0393 5d5eda4d8bc9b81df5bbb88c76225ccb 177 SMART SM00028 79 112 2.4E-4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0393 5d5eda4d8bc9b81df5bbb88c76225ccb 177 SMART SM00028 113 146 0.0014 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0393 5d5eda4d8bc9b81df5bbb88c76225ccb 177 SMART SM00028 10 43 31.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0393 5d5eda4d8bc9b81df5bbb88c76225ccb 177 Gene3D G3DSA:1.25.40.10 111 177 1.5E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0393 5d5eda4d8bc9b81df5bbb88c76225ccb 177 Gene3D G3DSA:1.25.40.10 3 110 1.8E-22 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0393 5d5eda4d8bc9b81df5bbb88c76225ccb 177 SUPERFAMILY SSF48452 8 175 3.79E-34 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0299 beb2b2e92ebfc7afc2f4907ad6a5c45f 285 Pfam PF01734 Patatin-like phospholipase 6 174 1.6E-20 T 23-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Mlab_0299 beb2b2e92ebfc7afc2f4907ad6a5c45f 285 SUPERFAMILY SSF52151 3 256 3.92E-42 T 23-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Mlab_0299 beb2b2e92ebfc7afc2f4907ad6a5c45f 285 Gene3D G3DSA:3.40.1090.10 89 206 3.5E-18 T 23-10-2018 Mlab_0299 beb2b2e92ebfc7afc2f4907ad6a5c45f 285 Gene3D G3DSA:3.40.1090.10 2 65 6.9E-7 T 23-10-2018 Mlab_1658 2ff39b2ea50d056056f95b0b416c7239 308 Pfam PF02475 Met-10+ like-protein 70 260 5.9E-46 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 Mlab_1658 2ff39b2ea50d056056f95b0b416c7239 308 SUPERFAMILY SSF53335 69 305 1.01E-48 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1658 2ff39b2ea50d056056f95b0b416c7239 308 Gene3D G3DSA:3.40.50.150 68 306 9.3E-53 T 23-10-2018 Mlab_1349 0e6747e7ff8fa97ed5fbdb9d03bb2f2d 112 SUPERFAMILY SSF46934 71 110 5.87E-5 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 Mlab_1349 0e6747e7ff8fa97ed5fbdb9d03bb2f2d 112 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 8 110 19.033 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 Mlab_1349 0e6747e7ff8fa97ed5fbdb9d03bb2f2d 112 Pfam PF01849 NAC domain 7 64 4.8E-14 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain Mlab_1349 0e6747e7ff8fa97ed5fbdb9d03bb2f2d 112 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 1 110 2.2E-31 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 Mlab_1349 0e6747e7ff8fa97ed5fbdb9d03bb2f2d 112 Gene3D G3DSA:2.20.70.30 11 71 8.4E-16 T 23-10-2018 IPR038187 NAC A/B domain superfamily Mlab_1349 0e6747e7ff8fa97ed5fbdb9d03bb2f2d 112 SMART SM01407 7 66 1.2E-19 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain Mlab_1349 0e6747e7ff8fa97ed5fbdb9d03bb2f2d 112 Gene3D G3DSA:1.10.8.10 72 110 2.3E-16 T 23-10-2018 Mlab_1370 c09bde503e24269b2e20c10c3e42c3b7 474 SUPERFAMILY SSF55681 202 469 3.2E-64 T 23-10-2018 Mlab_1370 c09bde503e24269b2e20c10c3e42c3b7 474 Gene3D G3DSA:3.30.930.10 217 474 1.6E-83 T 23-10-2018 Mlab_1370 c09bde503e24269b2e20c10c3e42c3b7 474 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 470 35.423 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 Mlab_1370 c09bde503e24269b2e20c10c3e42c3b7 474 Gene3D G3DSA:1.10.10.2310 24 196 1.6E-16 T 23-10-2018 Mlab_1370 c09bde503e24269b2e20c10c3e42c3b7 474 Gene3D G3DSA:1.10.10.2320 61 151 1.6E-16 T 23-10-2018 Mlab_1370 c09bde503e24269b2e20c10c3e42c3b7 474 Gene3D G3DSA:1.10.10.2330 74 125 1.6E-16 T 23-10-2018 Mlab_1370 c09bde503e24269b2e20c10c3e42c3b7 474 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 165 469 3.6E-111 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Mlab_1370 c09bde503e24269b2e20c10c3e42c3b7 474 Pfam PF01409 tRNA synthetases class II core domain (F) 206 467 5.7E-85 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 Mlab_1493 dc0c25b2ca164196a4340d67f48eed92 238 SUPERFAMILY SSF53448 5 234 4.88E-38 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1493 dc0c25b2ca164196a4340d67f48eed92 238 Pfam PF00535 Glycosyl transferase family 2 8 172 8.3E-26 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Mlab_1493 dc0c25b2ca164196a4340d67f48eed92 238 Gene3D G3DSA:3.90.550.10 2 238 4.6E-41 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0063 305f09dfd67c19c4624c6fd7190a63bc 59 SUPERFAMILY SSF158997 3 59 4.32E-14 T 23-10-2018 Mlab_0063 305f09dfd67c19c4624c6fd7190a63bc 59 Gene3D G3DSA:2.20.25.10 8 59 1.3E-13 T 23-10-2018 Mlab_0063 305f09dfd67c19c4624c6fd7190a63bc 59 Pfam PF03966 Trm112p-like protein 2 49 7.1E-11 T 23-10-2018 IPR005651 Trm112-like Mlab_0804 89fda638bf7c59fbdab10694d9e67acb 121 Gene3D G3DSA:3.40.1490.10 8 121 1.1E-39 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 Mlab_0804 89fda638bf7c59fbdab10694d9e67acb 121 SUPERFAMILY SSF102462 9 121 6.45E-39 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 Mlab_0804 89fda638bf7c59fbdab10694d9e67acb 121 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 10 121 3.2E-37 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 Mlab_0804 89fda638bf7c59fbdab10694d9e67acb 121 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 11 121 3.0E-38 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 Mlab_0326 b14c329342e6bb41f621ddbbf8083a82 276 Gene3D G3DSA:3.40.50.150 2 217 9.1E-17 T 23-10-2018 Mlab_0326 b14c329342e6bb41f621ddbbf8083a82 276 Pfam PF13489 Methyltransferase domain 50 161 4.7E-8 T 23-10-2018 Mlab_0326 b14c329342e6bb41f621ddbbf8083a82 276 SUPERFAMILY SSF53335 49 201 1.2E-18 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1333 db2f7a5471213abfefcc99b22eef2000 221 Pfam PF00977 Histidine biosynthesis protein 3 210 3.4E-22 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Mlab_1333 db2f7a5471213abfefcc99b22eef2000 221 Gene3D G3DSA:3.20.20.70 1 218 2.7E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1333 db2f7a5471213abfefcc99b22eef2000 221 SUPERFAMILY SSF51366 1 214 6.47E-28 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 SUPERFAMILY SSF48557 4 439 5.18E-122 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 PRINTS PR00149 Fumarate lyase superfamily signature 94 112 1.1E-23 T 23-10-2018 IPR000362 Fumarate lyase family Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 PRINTS PR00149 Fumarate lyase superfamily signature 225 252 1.1E-23 T 23-10-2018 IPR000362 Fumarate lyase family Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 1.1E-23 T 23-10-2018 IPR000362 Fumarate lyase family Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 PRINTS PR00149 Fumarate lyase superfamily signature 270 286 1.1E-23 T 23-10-2018 IPR000362 Fumarate lyase family Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 437 3.3E-151 T 23-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 SMART SM00998 358 438 7.6E-29 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 Pfam PF00206 Lyase 12 291 3.6E-51 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 ProSitePatterns PS00163 Fumarate lyases signature. 270 279 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 PRINTS PR00145 Argininosuccinate lyase family signature 270 286 6.5E-7 T 23-10-2018 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 PRINTS PR00145 Argininosuccinate lyase family signature 134 154 6.5E-7 T 23-10-2018 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 PRINTS PR00145 Argininosuccinate lyase family signature 225 249 6.5E-7 T 23-10-2018 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 PRINTS PR00145 Argininosuccinate lyase family signature 93 115 6.5E-7 T 23-10-2018 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 Gene3D G3DSA:1.10.40.30 358 438 1.8E-20 T 23-10-2018 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 Pfam PF10397 Adenylosuccinate lyase C-terminus 359 436 4.4E-19 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 Gene3D G3DSA:1.20.200.10 99 357 1.4E-85 T 23-10-2018 Mlab_1121 0386d8457cd84d5708765ed99ea16a35 447 Gene3D G3DSA:1.10.275.10 1 98 4.8E-28 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal Mlab_0420 f77395ff243324a57526d481ea3352ec 317 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 182 193 - T 23-10-2018 IPR000241 Putative RNA methylase domain Mlab_0420 f77395ff243324a57526d481ea3352ec 317 Pfam PF01170 Putative RNA methylase family UPF0020 149 311 2.2E-26 T 23-10-2018 IPR000241 Putative RNA methylase domain Mlab_0420 f77395ff243324a57526d481ea3352ec 317 Gene3D G3DSA:3.40.50.150 150 317 8.7E-35 T 23-10-2018 Mlab_0420 f77395ff243324a57526d481ea3352ec 317 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 260 284 2.7E-5 T 23-10-2018 Mlab_0420 f77395ff243324a57526d481ea3352ec 317 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 238 250 2.7E-5 T 23-10-2018 Mlab_0420 f77395ff243324a57526d481ea3352ec 317 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 180 194 2.7E-5 T 23-10-2018 Mlab_0420 f77395ff243324a57526d481ea3352ec 317 SUPERFAMILY SSF53335 129 285 2.49E-31 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1265 83b90ce5b4c3c5baabbe3b7a511c3e47 395 SUPERFAMILY SSF55031 168 296 4.49E-16 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Mlab_1265 83b90ce5b4c3c5baabbe3b7a511c3e47 395 Pfam PF07687 Peptidase dimerisation domain 165 293 1.7E-14 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain Mlab_1265 83b90ce5b4c3c5baabbe3b7a511c3e47 395 Gene3D G3DSA:3.30.70.360 173 295 3.0E-24 T 23-10-2018 Mlab_1265 83b90ce5b4c3c5baabbe3b7a511c3e47 395 Gene3D G3DSA:3.40.630.10 296 386 2.0E-7 T 23-10-2018 Mlab_1265 83b90ce5b4c3c5baabbe3b7a511c3e47 395 Pfam PF01546 Peptidase family M20/M25/M40 62 386 1.4E-37 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 Mlab_1265 83b90ce5b4c3c5baabbe3b7a511c3e47 395 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 96 133 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Mlab_1265 83b90ce5b4c3c5baabbe3b7a511c3e47 395 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 61 70 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Mlab_1265 83b90ce5b4c3c5baabbe3b7a511c3e47 395 SUPERFAMILY SSF53187 4 389 6.01E-55 T 23-10-2018 Mlab_1265 83b90ce5b4c3c5baabbe3b7a511c3e47 395 Gene3D G3DSA:3.40.630.10 1 172 2.0E-41 T 23-10-2018 Mlab_0247 4bbdeb6f358486b955ab259f405d6674 307 Gene3D G3DSA:3.30.70.20 159 218 1.7E-11 T 23-10-2018 Mlab_0247 4bbdeb6f358486b955ab259f405d6674 307 SUPERFAMILY SSF56014 97 293 3.79E-36 T 23-10-2018 Mlab_0247 4bbdeb6f358486b955ab259f405d6674 307 Pfam PF00037 4Fe-4S binding domain 164 185 8.4E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0247 4bbdeb6f358486b955ab259f405d6674 307 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 96 287 2.0E-24 T 23-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Mlab_0247 4bbdeb6f358486b955ab259f405d6674 307 PRINTS PR00397 Sirohaem Fe-binding site signature 141 159 5.1E-5 T 23-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Mlab_0247 4bbdeb6f358486b955ab259f405d6674 307 PRINTS PR00397 Sirohaem Fe-binding site signature 98 116 5.1E-5 T 23-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Mlab_0247 4bbdeb6f358486b955ab259f405d6674 307 SUPERFAMILY SSF54862 143 224 7.99E-15 T 23-10-2018 Mlab_0247 4bbdeb6f358486b955ab259f405d6674 307 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 20 85 5.7E-22 T 23-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Mlab_0247 4bbdeb6f358486b955ab259f405d6674 307 Gene3D G3DSA:3.90.480.10 28 96 1.1E-8 T 23-10-2018 Mlab_0247 4bbdeb6f358486b955ab259f405d6674 307 SUPERFAMILY SSF55124 15 109 3.2E-21 T 23-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Mlab_0165 df77d52c454e77123aedc4297f27f6f5 268 PIRSF PIRSF000363 1 268 9.5E-111 T 23-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 Mlab_0165 df77d52c454e77123aedc4297f27f6f5 268 ProSitePatterns PS00692 NifH/frxC family signature 2. 119 132 - T 23-10-2018 IPR030655 NifH/chlL conserved site Mlab_0165 df77d52c454e77123aedc4297f27f6f5 268 SUPERFAMILY SSF52540 1 266 2.31E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0165 df77d52c454e77123aedc4297f27f6f5 268 ProSitePatterns PS00746 NifH/frxC family signature 1. 83 95 - T 23-10-2018 IPR030655 NifH/chlL conserved site Mlab_0165 df77d52c454e77123aedc4297f27f6f5 268 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 2 266 2.8E-106 T 23-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 Mlab_0165 df77d52c454e77123aedc4297f27f6f5 268 Gene3D G3DSA:3.40.50.300 1 268 4.4E-60 T 23-10-2018 Mlab_0165 df77d52c454e77123aedc4297f27f6f5 268 PRINTS PR00091 Nitrogenase component II signature 7 20 4.9E-33 T 23-10-2018 Mlab_0165 df77d52c454e77123aedc4297f27f6f5 268 PRINTS PR00091 Nitrogenase component II signature 118 133 4.9E-33 T 23-10-2018 Mlab_0165 df77d52c454e77123aedc4297f27f6f5 268 PRINTS PR00091 Nitrogenase component II signature 29 44 4.9E-33 T 23-10-2018 Mlab_0165 df77d52c454e77123aedc4297f27f6f5 268 PRINTS PR00091 Nitrogenase component II signature 81 95 4.9E-33 T 23-10-2018 Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 Pfam PF00118 TCP-1/cpn60 chaperonin family 37 522 2.7E-181 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 SUPERFAMILY SSF48592 18 522 1.06E-94 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 Gene3D G3DSA:3.30.260.10 148 403 8.1E-204 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 SUPERFAMILY SSF52029 210 376 2.51E-57 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 9 522 5.8E-237 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 90 98 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 Gene3D G3DSA:1.10.560.10 29 520 8.1E-204 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 41 53 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 405 417 1.4E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 60 78 1.4E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 38 54 1.4E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 371 393 1.4E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 90 109 1.4E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 SUPERFAMILY SSF54849 151 403 1.68E-24 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 Gene3D G3DSA:3.50.7.10 216 367 8.1E-204 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily Mlab_0206 911ee82a03b3a78aab049532103be8d6 551 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 62 78 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 Mlab_0363 5aa603b19d2873094144bcd93dda6de1 421 ProSitePatterns PS00483 Dihydroorotase signature 2. 279 290 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Mlab_0363 5aa603b19d2873094144bcd93dda6de1 421 SUPERFAMILY SSF51556 51 341 9.67E-71 T 23-10-2018 IPR032466 Metal-dependent hydrolase Mlab_0363 5aa603b19d2873094144bcd93dda6de1 421 Gene3D G3DSA:3.20.20.140 50 344 2.3E-92 T 23-10-2018 Mlab_0363 5aa603b19d2873094144bcd93dda6de1 421 Pfam PF01979 Amidohydrolase family 47 356 4.2E-11 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Mlab_0363 5aa603b19d2873094144bcd93dda6de1 421 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 392 5.2E-90 T 23-10-2018 Mlab_0363 5aa603b19d2873094144bcd93dda6de1 421 SUPERFAMILY SSF51338 1 403 1.82E-15 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_0363 5aa603b19d2873094144bcd93dda6de1 421 Gene3D G3DSA:2.30.40.10 15 392 2.3E-92 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 SMART SM00963 48 124 1.3E-4 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 Pfam PF02881 SRP54-type protein, helical bundle domain 57 112 2.7E-8 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 64 334 8.6E-91 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 SUPERFAMILY SSF52540 136 335 1.05E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 Pfam PF00448 SRP54-type protein, GTPase domain 141 334 1.1E-65 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 308 321 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 Gene3D G3DSA:1.20.120.140 18 126 2.4E-21 T 23-10-2018 Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 63 335 54.98 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 Gene3D G3DSA:3.40.50.300 129 334 9.0E-69 T 23-10-2018 Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 SMART SM00962 140 335 4.0E-92 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 SMART SM00382 139 315 3.1E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1475 a358a51de83f62c97fa32124a8d3c049 337 SUPERFAMILY SSF47364 57 127 7.59E-12 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 Mlab_1184 b77897324145f9074d13f83bc043406e 339 Pfam PF02517 CAAX protease self-immunity 191 291 2.8E-11 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 Mlab_1257 233ae7308cb4530132cc24faa95d091f 639 SMART SM00382 425 611 7.3E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1257 233ae7308cb4530132cc24faa95d091f 639 Gene3D G3DSA:1.20.1560.10 17 356 5.1E-90 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Mlab_1257 233ae7308cb4530132cc24faa95d091f 639 Gene3D G3DSA:3.40.50.300 398 632 7.6E-95 T 23-10-2018 Mlab_1257 233ae7308cb4530132cc24faa95d091f 639 ProSitePatterns PS00211 ABC transporters family signature. 537 551 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1257 233ae7308cb4530132cc24faa95d091f 639 Pfam PF00005 ABC transporter 416 565 8.7E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1257 233ae7308cb4530132cc24faa95d091f 639 SUPERFAMILY SSF90123 27 353 5.23E-76 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Mlab_1257 233ae7308cb4530132cc24faa95d091f 639 Pfam PF00664 ABC transporter transmembrane region 47 324 4.5E-48 T 23-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Mlab_1257 233ae7308cb4530132cc24faa95d091f 639 SUPERFAMILY SSF52540 391 633 7.14E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0418 067bf84af20406bb49ede95e5d404d39 363 SUPERFAMILY SSF103473 6 354 3.01E-28 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_0418 067bf84af20406bb49ede95e5d404d39 363 Pfam PF07690 Major Facilitator Superfamily 9 307 3.0E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_0418 067bf84af20406bb49ede95e5d404d39 363 Gene3D G3DSA:1.20.1250.20 4 174 2.1E-16 T 23-10-2018 Mlab_0418 067bf84af20406bb49ede95e5d404d39 363 Gene3D G3DSA:1.20.1250.20 194 355 4.2E-8 T 23-10-2018 Mlab_0291 8146c8eb4919bee2358f9aec18c7dbbc 408 Gene3D G3DSA:1.10.8.260 266 330 2.8E-115 T 23-10-2018 IPR023166 HI0933-like insert domain superfamily Mlab_0291 8146c8eb4919bee2358f9aec18c7dbbc 408 Pfam PF03486 HI0933-like protein 6 400 5.3E-111 T 23-10-2018 Mlab_0291 8146c8eb4919bee2358f9aec18c7dbbc 408 SUPERFAMILY SSF51905 3 403 3.76E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0291 8146c8eb4919bee2358f9aec18c7dbbc 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.5E-6 T 23-10-2018 Mlab_0291 8146c8eb4919bee2358f9aec18c7dbbc 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 6.5E-6 T 23-10-2018 Mlab_0291 8146c8eb4919bee2358f9aec18c7dbbc 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 6.5E-6 T 23-10-2018 Mlab_0291 8146c8eb4919bee2358f9aec18c7dbbc 408 Gene3D G3DSA:3.50.50.60 9 396 2.8E-115 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0291 8146c8eb4919bee2358f9aec18c7dbbc 408 SUPERFAMILY SSF160996 192 348 3.01E-30 T 23-10-2018 Mlab_0291 8146c8eb4919bee2358f9aec18c7dbbc 408 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 8 400 5.6E-133 T 23-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like Mlab_0291 8146c8eb4919bee2358f9aec18c7dbbc 408 Gene3D G3DSA:2.40.30.10 191 347 2.8E-115 T 23-10-2018 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 Pfam PF00701 Dihydrodipicolinate synthetase family 2 289 2.1E-84 T 23-10-2018 IPR002220 DapA-like GO:0016829 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 SMART SM01130 1 297 1.9E-125 T 23-10-2018 IPR002220 DapA-like GO:0016829 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 23-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 295 2.1E-90 T 23-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 SUPERFAMILY SSF51569 2 296 1.67E-92 T 23-10-2018 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 Gene3D G3DSA:3.20.20.70 1 297 1.1E-100 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 PIRSF PIRSF001365 1 296 2.7E-85 T 23-10-2018 IPR002220 DapA-like GO:0016829 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 6.0E-32 T 23-10-2018 IPR002220 DapA-like GO:0016829 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 6.0E-32 T 23-10-2018 IPR002220 DapA-like GO:0016829 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 6.0E-32 T 23-10-2018 IPR002220 DapA-like GO:0016829 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 6.0E-32 T 23-10-2018 IPR002220 DapA-like GO:0016829 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 165 - T 23-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 Mlab_0530 646f3c0a370e354c186ae17ec9275577 297 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 295 59.63 T 23-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_0267 cbdd33015f4ea96e96736580b1a8f77e 288 Gene3D G3DSA:3.40.50.300 18 269 6.7E-84 T 23-10-2018 Mlab_0267 cbdd33015f4ea96e96736580b1a8f77e 288 Hamap MF_02040 Iron-sulfur cluster carrier protein. 25 280 36.99 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein Mlab_0267 cbdd33015f4ea96e96736580b1a8f77e 288 SUPERFAMILY SSF52540 30 261 1.4E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0267 cbdd33015f4ea96e96736580b1a8f77e 288 ProSitePatterns PS01215 Mrp family signature. 140 156 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 Mlab_0267 cbdd33015f4ea96e96736580b1a8f77e 288 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 32 279 3.1E-99 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 Mlab_1624 4b408dd3be4e209aaf0211762347dfaf 663 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 138 185 4.5E-10 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_1624 4b408dd3be4e209aaf0211762347dfaf 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 4.0E-27 T 23-10-2018 Mlab_1624 4b408dd3be4e209aaf0211762347dfaf 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 337 4.0E-27 T 23-10-2018 Mlab_1624 4b408dd3be4e209aaf0211762347dfaf 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 142 167 4.0E-27 T 23-10-2018 Mlab_1624 4b408dd3be4e209aaf0211762347dfaf 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 378 390 4.0E-27 T 23-10-2018 Mlab_1624 4b408dd3be4e209aaf0211762347dfaf 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 289 310 4.0E-27 T 23-10-2018 Mlab_1624 4b408dd3be4e209aaf0211762347dfaf 663 Pfam PF00361 Proton-conducting membrane transporter 201 473 2.5E-53 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0900 760a736f489fb556f97ae73d00287220 397 SUPERFAMILY SSF48179 197 292 4.76E-30 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Mlab_0900 760a736f489fb556f97ae73d00287220 397 Gene3D G3DSA:1.20.5.100 200 227 2.9E-19 T 23-10-2018 Mlab_0900 760a736f489fb556f97ae73d00287220 397 PIRSF PIRSF000124 1 397 1.8E-127 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 Mlab_0900 760a736f489fb556f97ae73d00287220 397 Gene3D G3DSA:3.40.50.720 228 397 2.5E-60 T 23-10-2018 Mlab_0900 760a736f489fb556f97ae73d00287220 397 Gene3D G3DSA:3.40.50.720 1 199 1.2E-58 T 23-10-2018 Mlab_0900 760a736f489fb556f97ae73d00287220 397 SUPERFAMILY SSF52413 305 395 1.09E-21 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 Mlab_0900 760a736f489fb556f97ae73d00287220 397 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 310 387 8.9E-8 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Mlab_0900 760a736f489fb556f97ae73d00287220 397 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 287 1.4E-27 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Mlab_0900 760a736f489fb556f97ae73d00287220 397 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 385 1.6E-97 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 Mlab_0900 760a736f489fb556f97ae73d00287220 397 SUPERFAMILY SSF51735 1 200 2.37E-44 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0900 760a736f489fb556f97ae73d00287220 397 PIRSF PIRSF500134 348 397 11.0 T 23-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 Mlab_0900 760a736f489fb556f97ae73d00287220 397 PIRSF PIRSF500134 1 375 2.6E-113 T 23-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 Mlab_0900 760a736f489fb556f97ae73d00287220 397 SMART SM00984 309 396 1.3E-13 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Mlab_0900 760a736f489fb556f97ae73d00287220 397 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 168 1.2E-31 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Mlab_1177 2ef82ce30ed0106738e344b7d8cf0fbf 96 SUPERFAMILY SSF140371 1 86 3.01E-27 T 23-10-2018 IPR036519 Uncharacterised UPF0058 superfamily Mlab_1177 2ef82ce30ed0106738e344b7d8cf0fbf 96 Gene3D G3DSA:1.20.1270.110 1 96 2.0E-27 T 23-10-2018 IPR036519 Uncharacterised UPF0058 superfamily Mlab_1177 2ef82ce30ed0106738e344b7d8cf0fbf 96 Pfam PF01893 Uncharacterised protein family UPF0058 1 85 2.4E-29 T 23-10-2018 IPR002753 Uncharacterised protein family UPF0058 Mlab_0152 7e9a641ce53cf66942295ffee8578d4a 304 SUPERFAMILY SSF142338 2 301 6.54E-83 T 23-10-2018 Mlab_0152 7e9a641ce53cf66942295ffee8578d4a 304 Gene3D G3DSA:3.40.50.10680 6 271 2.7E-88 T 23-10-2018 Mlab_0152 7e9a641ce53cf66942295ffee8578d4a 304 Gene3D G3DSA:1.10.8.240 36 123 2.7E-88 T 23-10-2018 Mlab_0152 7e9a641ce53cf66942295ffee8578d4a 304 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 304 108.81 T 23-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 Mlab_0152 7e9a641ce53cf66942295ffee8578d4a 304 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 2 294 5.2E-101 T 23-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 Mlab_0152 7e9a641ce53cf66942295ffee8578d4a 304 Pfam PF01933 Uncharacterised protein family UPF0052 2 268 1.4E-48 T 23-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 Mlab_0729 cadb296c0886190d104e5f8c4d681dfd 545 ProSitePatterns PS00211 ABC transporters family signature. 177 191 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0729 cadb296c0886190d104e5f8c4d681dfd 545 TIGRFAM TIGR03269 met_CoM_red_A2: methyl coenzyme M reductase system, component A2 6 537 7.3E-247 T 23-10-2018 IPR017669 Methyl coenzyme M reductase system, component A2 Mlab_0729 cadb296c0886190d104e5f8c4d681dfd 545 Pfam PF00005 ABC transporter 309 463 7.3E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0729 cadb296c0886190d104e5f8c4d681dfd 545 Pfam PF00005 ABC transporter 24 204 1.6E-20 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0729 cadb296c0886190d104e5f8c4d681dfd 545 SUPERFAMILY SSF52540 3 267 1.26E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0729 cadb296c0886190d104e5f8c4d681dfd 545 SUPERFAMILY SSF52540 301 528 1.3E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0729 cadb296c0886190d104e5f8c4d681dfd 545 SMART SM00382 33 262 5.9E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0729 cadb296c0886190d104e5f8c4d681dfd 545 SMART SM00382 317 522 7.3E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0729 cadb296c0886190d104e5f8c4d681dfd 545 Gene3D G3DSA:3.40.50.300 4 283 5.4E-52 T 23-10-2018 Mlab_0729 cadb296c0886190d104e5f8c4d681dfd 545 Gene3D G3DSA:3.40.50.300 284 543 6.6E-55 T 23-10-2018 Mlab_0616 b2781cb7eecc0db095870022fa7d2a50 796 Pfam PF03104 DNA polymerase family B, exonuclease domain 65 292 2.3E-28 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_0616 b2781cb7eecc0db095870022fa7d2a50 796 Gene3D G3DSA:3.30.342.10 4 116 3.9E-17 T 23-10-2018 Mlab_0616 b2781cb7eecc0db095870022fa7d2a50 796 SUPERFAMILY SSF56672 375 782 1.17E-105 T 23-10-2018 Mlab_0616 b2781cb7eecc0db095870022fa7d2a50 796 SUPERFAMILY SSF53098 10 374 3.09E-70 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily Mlab_0616 b2781cb7eecc0db095870022fa7d2a50 796 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 405 418 5.8E-8 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_0616 b2781cb7eecc0db095870022fa7d2a50 796 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 537 545 5.8E-8 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_0616 b2781cb7eecc0db095870022fa7d2a50 796 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 485 497 5.8E-8 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_0616 b2781cb7eecc0db095870022fa7d2a50 796 Pfam PF00136 DNA polymerase family B 347 694 2.0E-50 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_0616 b2781cb7eecc0db095870022fa7d2a50 796 Gene3D G3DSA:3.90.1600.10 183 679 2.7E-123 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_0616 b2781cb7eecc0db095870022fa7d2a50 796 SMART SM00486 132 551 1.5E-73 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_0616 b2781cb7eecc0db095870022fa7d2a50 796 ProSitePatterns PS00116 DNA polymerase family B signature. 539 547 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_1701 41b591a6c66c5757fd1ef9df2ffce286 310 SUPERFAMILY SSF82689 180 275 4.32E-30 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 Mlab_1701 41b591a6c66c5757fd1ef9df2ffce286 310 Gene3D G3DSA:3.30.70.100 177 269 1.7E-26 T 23-10-2018 Mlab_1701 41b591a6c66c5757fd1ef9df2ffce286 310 SUPERFAMILY SSF50182 110 174 9.81E-18 T 23-10-2018 IPR010920 LSM domain superfamily Mlab_1701 41b591a6c66c5757fd1ef9df2ffce286 310 SUPERFAMILY SSF82861 27 108 2.48E-8 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 Mlab_1701 41b591a6c66c5757fd1ef9df2ffce286 310 Pfam PF00924 Mechanosensitive ion channel 67 264 9.0E-56 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Mlab_1701 41b591a6c66c5757fd1ef9df2ffce286 310 Gene3D G3DSA:2.30.30.60 125 174 3.1E-12 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily Mlab_0409 4fbf5a5f474adac12240b8aaa0d29a3c 200 Pfam PF10050 Predicted metal-binding protein (DUF2284) 25 198 1.4E-47 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding Mlab_0620 6a5195fd40c36b0c31d63596e3f9af1e 546 Gene3D G3DSA:1.10.3260.10 1 218 2.3E-55 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 Mlab_0620 6a5195fd40c36b0c31d63596e3f9af1e 546 SUPERFAMILY SSF117018 2 229 9.94E-56 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 Mlab_0620 6a5195fd40c36b0c31d63596e3f9af1e 546 Pfam PF01068 ATP dependent DNA ligase domain 224 413 6.7E-50 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 Mlab_0620 6a5195fd40c36b0c31d63596e3f9af1e 546 SUPERFAMILY SSF56091 218 413 6.0E-48 T 23-10-2018 Mlab_0620 6a5195fd40c36b0c31d63596e3f9af1e 546 Gene3D G3DSA:2.40.50.140 414 546 9.4E-42 T 23-10-2018 Mlab_0620 6a5195fd40c36b0c31d63596e3f9af1e 546 Gene3D G3DSA:3.30.470.30 220 412 5.0E-57 T 23-10-2018 Mlab_0620 6a5195fd40c36b0c31d63596e3f9af1e 546 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 58 536 4.2E-116 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 Mlab_0620 6a5195fd40c36b0c31d63596e3f9af1e 546 Pfam PF04675 DNA ligase N terminus 3 175 2.0E-30 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 Mlab_0620 6a5195fd40c36b0c31d63596e3f9af1e 546 Hamap MF_00407 DNA ligase [lig]. 1 540 28.749 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 Mlab_0620 6a5195fd40c36b0c31d63596e3f9af1e 546 SUPERFAMILY SSF50249 416 542 8.48E-33 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0620 6a5195fd40c36b0c31d63596e3f9af1e 546 Pfam PF04679 ATP dependent DNA ligase C terminal region 433 524 3.2E-18 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 Mlab_1061 1b121f6104ed400406b26e8047d1093a 280 Gene3D G3DSA:1.10.3720.10 85 274 1.5E-34 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1061 1b121f6104ed400406b26e8047d1093a 280 SUPERFAMILY SSF161098 86 270 4.58E-42 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1061 1b121f6104ed400406b26e8047d1093a 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 276 1.2E-26 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_1433 3ad8443deb255d8f2c6d8de81f374147 248 Gene3D G3DSA:3.60.110.10 1 247 1.2E-61 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Mlab_1433 3ad8443deb255d8f2c6d8de81f374147 248 Pfam PF00795 Carbon-nitrogen hydrolase 3 242 3.6E-30 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Mlab_1433 3ad8443deb255d8f2c6d8de81f374147 248 SUPERFAMILY SSF56317 1 246 8.5E-54 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 Gene3D G3DSA:3.30.1640.10 2 109 1.6E-14 T 23-10-2018 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 Gene3D G3DSA:3.40.50.300 272 626 2.6E-129 T 23-10-2018 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 Pfam PF17207 MCM OB domain 111 238 2.3E-31 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 SMART SM00350 108 622 1.3E-181 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 Gene3D G3DSA:2.20.28.10 139 188 1.5E-41 T 23-10-2018 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 SUPERFAMILY SSF50249 19 257 7.2E-49 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 Pfam PF00493 MCM2/3/5 family 277 621 1.3E-131 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 Gene3D G3DSA:1.10.10.10 627 713 7.3E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 PRINTS PR01660 Mini-chromosome maintenance (MCM) protein 4 signature 134 147 2.8E-5 T 23-10-2018 IPR008047 Mini-chromosome maintenance complex protein 4 GO:0003677|GO:0003678|GO:0005524|GO:0006270|GO:0042555 Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 PRINTS PR01660 Mini-chromosome maintenance (MCM) protein 4 signature 304 315 2.8E-5 T 23-10-2018 IPR008047 Mini-chromosome maintenance complex protein 4 GO:0003677|GO:0003678|GO:0005524|GO:0006270|GO:0042555 Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 PRINTS PR01660 Mini-chromosome maintenance (MCM) protein 4 signature 182 194 2.8E-5 T 23-10-2018 IPR008047 Mini-chromosome maintenance complex protein 4 GO:0003677|GO:0003678|GO:0005524|GO:0006270|GO:0042555 Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 PRINTS PR01660 Mini-chromosome maintenance (MCM) protein 4 signature 451 468 2.8E-5 T 23-10-2018 IPR008047 Mini-chromosome maintenance complex protein 4 GO:0003677|GO:0003678|GO:0005524|GO:0006270|GO:0042555 Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 PRINTS PR01660 Mini-chromosome maintenance (MCM) protein 4 signature 622 631 2.8E-5 T 23-10-2018 IPR008047 Mini-chromosome maintenance complex protein 4 GO:0003677|GO:0003678|GO:0005524|GO:0006270|GO:0042555 Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 418 431 2.1E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 442 454 2.1E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 390 404 2.1E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 469 477 2.1E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 329 344 2.1E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 SUPERFAMILY SSF52540 298 634 1.33E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 Gene3D G3DSA:2.40.50.140 112 250 1.5E-41 T 23-10-2018 Mlab_0830 3fb0ac3f5b76e5b116e26056241ee56e 717 SMART SM00382 330 484 0.0071 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1366 c4d0f08f444cad6c5b03bb198c648926 252 Gene3D G3DSA:3.30.1380.20 101 251 1.4E-21 T 23-10-2018 Mlab_1366 c4d0f08f444cad6c5b03bb198c648926 252 Pfam PF01047 MarR family 29 80 1.4E-10 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_1366 c4d0f08f444cad6c5b03bb198c648926 252 SMART SM00418 18 99 3.5E-6 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_1366 c4d0f08f444cad6c5b03bb198c648926 252 Gene3D G3DSA:1.10.10.10 23 90 5.6E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1366 c4d0f08f444cad6c5b03bb198c648926 252 SUPERFAMILY SSF46785 24 111 6.94E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1366 c4d0f08f444cad6c5b03bb198c648926 252 Pfam PF02830 V4R domain 192 249 2.8E-10 T 23-10-2018 IPR004096 4-vinyl reductase, 4VR Mlab_1366 c4d0f08f444cad6c5b03bb198c648926 252 SMART SM00989 189 251 1.6E-15 T 23-10-2018 IPR004096 4-vinyl reductase, 4VR Mlab_1366 c4d0f08f444cad6c5b03bb198c648926 252 SUPERFAMILY SSF111126 103 249 5.18E-28 T 23-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily Mlab_1366 c4d0f08f444cad6c5b03bb198c648926 252 SMART SM00347 19 116 0.0062 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_1408 99b5741fed0d573f2d16234f50112806 268 SUPERFAMILY SSF51366 4 267 1.33E-73 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_1408 99b5741fed0d573f2d16234f50112806 268 Gene3D G3DSA:3.20.20.70 1 268 6.0E-101 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1408 99b5741fed0d573f2d16234f50112806 268 Pfam PF00977 Histidine biosynthesis protein 6 251 3.4E-84 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Mlab_1408 99b5741fed0d573f2d16234f50112806 268 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 267 2.0E-116 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 Mlab_1408 99b5741fed0d573f2d16234f50112806 268 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 267 46.621 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 Mlab_1374 1d13b02bab56e26d60d60df6695e6268 331 Gene3D G3DSA:3.40.50.1980 159 294 5.5E-36 T 23-10-2018 Mlab_1374 1d13b02bab56e26d60d60df6695e6268 331 SUPERFAMILY SSF53807 22 295 1.41E-71 T 23-10-2018 Mlab_1374 1d13b02bab56e26d60d60df6695e6268 331 Gene3D G3DSA:3.40.50.1980 28 158 1.0E-35 T 23-10-2018 Mlab_1374 1d13b02bab56e26d60d60df6695e6268 331 Pfam PF01497 Periplasmic binding protein 43 272 3.7E-37 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain Mlab_0226 0b915822a38b7974d02f70cd13e60022 281 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 280 33.513 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 Mlab_0226 0b915822a38b7974d02f70cd13e60022 281 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 274 1.1E-61 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 Mlab_0226 0b915822a38b7974d02f70cd13e60022 281 Gene3D G3DSA:3.20.20.150 1 279 7.1E-81 T 23-10-2018 Mlab_0226 0b915822a38b7974d02f70cd13e60022 281 SUPERFAMILY SSF51658 2 278 4.84E-71 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily Mlab_0226 0b915822a38b7974d02f70cd13e60022 281 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 174 181 - T 23-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 Mlab_0226 0b915822a38b7974d02f70cd13e60022 281 SMART SM00518 3 280 1.7E-59 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 Mlab_0226 0b915822a38b7974d02f70cd13e60022 281 Pfam PF01261 Xylose isomerase-like TIM barrel 19 236 6.5E-22 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 2.6E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 237 252 2.6E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 209 222 2.6E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 2.6E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 Gene3D G3DSA:3.40.120.10 174 364 7.3E-64 T 23-10-2018 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 Gene3D G3DSA:3.40.120.10 258 369 7.3E-64 T 23-10-2018 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 SUPERFAMILY SSF55957 365 457 2.72E-18 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 SUPERFAMILY SSF53738 158 259 1.84E-26 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 Gene3D G3DSA:3.40.120.10 8 155 5.4E-48 T 23-10-2018 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 Gene3D G3DSA:3.30.310.50 376 457 2.2E-15 T 23-10-2018 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 257 1.7E-25 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 9 135 4.9E-41 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 374 2.5E-22 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 9 452 2.1E-165 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 396 454 1.0E-11 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 SUPERFAMILY SSF53738 7 182 1.92E-43 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 SUPERFAMILY SSF53738 261 373 5.1E-23 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0785 8c9833d2a6bdeb1cb4e58143937d282d 458 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0944 2a0641f1026ab759c6bfec164282ecd8 201 SUPERFAMILY SSF58014 59 143 1.44E-23 T 23-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 Mlab_0944 2a0641f1026ab759c6bfec164282ecd8 201 Pfam PF01025 GrpE 41 198 4.7E-44 T 23-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Mlab_0944 2a0641f1026ab759c6bfec164282ecd8 201 ProSitePatterns PS01071 grpE protein signature. 154 196 - T 23-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Mlab_0944 2a0641f1026ab759c6bfec164282ecd8 201 Hamap MF_01151 Protein GrpE [grpE]. 27 198 18.332 T 23-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Mlab_0944 2a0641f1026ab759c6bfec164282ecd8 201 Gene3D G3DSA:2.30.22.10 143 201 7.3E-18 T 23-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 Mlab_0944 2a0641f1026ab759c6bfec164282ecd8 201 Gene3D G3DSA:3.90.20.20 27 141 2.4E-25 T 23-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 Mlab_0944 2a0641f1026ab759c6bfec164282ecd8 201 SUPERFAMILY SSF51064 144 200 2.35E-13 T 23-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 Mlab_0944 2a0641f1026ab759c6bfec164282ecd8 201 PRINTS PR00773 GrpE protein signature 74 90 8.0E-24 T 23-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Mlab_0944 2a0641f1026ab759c6bfec164282ecd8 201 PRINTS PR00773 GrpE protein signature 102 117 8.0E-24 T 23-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Mlab_0944 2a0641f1026ab759c6bfec164282ecd8 201 PRINTS PR00773 GrpE protein signature 177 196 8.0E-24 T 23-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Mlab_0944 2a0641f1026ab759c6bfec164282ecd8 201 PRINTS PR00773 GrpE protein signature 151 166 8.0E-24 T 23-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Mlab_1723 5851d8e970ae5a320fde389846a0aa60 341 Gene3D G3DSA:3.30.360.10 140 307 9.8E-135 T 23-10-2018 Mlab_1723 5851d8e970ae5a320fde389846a0aa60 341 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 341 188.077 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 Mlab_1723 5851d8e970ae5a320fde389846a0aa60 341 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 138 145 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1723 5851d8e970ae5a320fde389846a0aa60 341 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 145 272 3.6E-26 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1723 5851d8e970ae5a320fde389846a0aa60 341 SMART SM00846 2 140 3.4E-18 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1723 5851d8e970ae5a320fde389846a0aa60 341 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 105 4.6E-11 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Mlab_1723 5851d8e970ae5a320fde389846a0aa60 341 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 4 337 2.1E-139 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 Mlab_1723 5851d8e970ae5a320fde389846a0aa60 341 PIRSF PIRSF000149 1 322 3.5E-76 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1723 5851d8e970ae5a320fde389846a0aa60 341 SUPERFAMILY SSF51735 2 158 9.74E-45 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1723 5851d8e970ae5a320fde389846a0aa60 341 SUPERFAMILY SSF55347 140 302 2.95E-51 T 23-10-2018 Mlab_1723 5851d8e970ae5a320fde389846a0aa60 341 Gene3D G3DSA:3.40.50.720 3 336 9.8E-135 T 23-10-2018 Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 Gene3D G3DSA:3.40.50.720 1 258 2.3E-81 T 23-10-2018 Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.6E-31 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.6E-31 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.6E-31 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.6E-31 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.6E-31 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.6E-31 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 5.0E-10 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 5.0E-10 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 5.0E-10 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 255 2.9E-60 T 23-10-2018 Mlab_0825 2a4fa6db6819c44dad6f8b4d68869f62 258 SUPERFAMILY SSF51735 9 255 5.83E-78 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1292 0a4d90c9700d34706263297fa1632ede 309 Gene3D G3DSA:3.90.550.10 2 226 1.7E-41 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1292 0a4d90c9700d34706263297fa1632ede 309 TIGRFAM TIGR04182 glyco_TIGR04182: glycosyltransferase, TIGR04182 family 5 295 3.0E-137 T 23-10-2018 IPR026456 Glycosyltransferase AglJ GO:0016757 Mlab_1292 0a4d90c9700d34706263297fa1632ede 309 SUPERFAMILY SSF53448 2 253 1.52E-37 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1292 0a4d90c9700d34706263297fa1632ede 309 Pfam PF00535 Glycosyl transferase family 2 7 128 6.6E-19 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 Gene3D G3DSA:3.40.50.1820 22 353 6.5E-143 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 Gene3D G3DSA:1.10.1740.110 180 285 6.5E-143 T 23-10-2018 Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 SUPERFAMILY SSF53474 19 364 8.75E-103 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 Gene3D G3DSA:3.10.580.10 367 483 3.2E-33 T 23-10-2018 Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 SMART SM00116 437 485 6.8E-7 T 23-10-2018 IPR000644 CBS domain Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 SMART SM00116 376 424 2.3E-7 T 23-10-2018 IPR000644 CBS domain Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 19 364 2.4E-134 T 23-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 SUPERFAMILY SSF54631 365 479 7.08E-31 T 23-10-2018 Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 Pfam PF00561 alpha/beta hydrolase fold 45 352 7.6E-34 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 13 365 31.273 T 23-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 Pfam PF00571 CBS domain 431 478 7.1E-11 T 23-10-2018 IPR000644 CBS domain Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 Pfam PF00571 CBS domain 369 423 5.9E-13 T 23-10-2018 IPR000644 CBS domain Mlab_0545 6b7b4068723b054e9d4ddeeff1e5bb4b 487 PIRSF PIRSF000443 2 375 5.6E-150 T 23-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 Mlab_0576 536262abe449843d055c00878d913db4 492 SUPERFAMILY SSF48557 15 458 1.88E-115 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 Mlab_0576 536262abe449843d055c00878d913db4 492 Pfam PF00206 Lyase 9 303 3.0E-59 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal Mlab_0576 536262abe449843d055c00878d913db4 492 PRINTS PR00149 Fumarate lyase superfamily signature 278 294 4.5E-26 T 23-10-2018 IPR000362 Fumarate lyase family Mlab_0576 536262abe449843d055c00878d913db4 492 PRINTS PR00149 Fumarate lyase superfamily signature 150 168 4.5E-26 T 23-10-2018 IPR000362 Fumarate lyase family Mlab_0576 536262abe449843d055c00878d913db4 492 PRINTS PR00149 Fumarate lyase superfamily signature 105 123 4.5E-26 T 23-10-2018 IPR000362 Fumarate lyase family Mlab_0576 536262abe449843d055c00878d913db4 492 PRINTS PR00149 Fumarate lyase superfamily signature 234 261 4.5E-26 T 23-10-2018 IPR000362 Fumarate lyase family Mlab_0576 536262abe449843d055c00878d913db4 492 PRINTS PR00145 Argininosuccinate lyase family signature 145 165 2.3E-50 T 23-10-2018 Mlab_0576 536262abe449843d055c00878d913db4 492 PRINTS PR00145 Argininosuccinate lyase family signature 196 212 2.3E-50 T 23-10-2018 Mlab_0576 536262abe449843d055c00878d913db4 492 PRINTS PR00145 Argininosuccinate lyase family signature 313 332 2.3E-50 T 23-10-2018 Mlab_0576 536262abe449843d055c00878d913db4 492 PRINTS PR00145 Argininosuccinate lyase family signature 104 126 2.3E-50 T 23-10-2018 Mlab_0576 536262abe449843d055c00878d913db4 492 PRINTS PR00145 Argininosuccinate lyase family signature 278 294 2.3E-50 T 23-10-2018 Mlab_0576 536262abe449843d055c00878d913db4 492 PRINTS PR00145 Argininosuccinate lyase family signature 234 258 2.3E-50 T 23-10-2018 Mlab_0576 536262abe449843d055c00878d913db4 492 Hamap MF_00006 Argininosuccinate lyase [argH]. 5 460 38.208 T 23-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Mlab_0576 536262abe449843d055c00878d913db4 492 Gene3D G3DSA:1.10.275.10 33 232 6.5E-153 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal Mlab_0576 536262abe449843d055c00878d913db4 492 Gene3D G3DSA:1.20.200.10 122 456 6.5E-153 T 23-10-2018 Mlab_0576 536262abe449843d055c00878d913db4 492 TIGRFAM TIGR00838 argH: argininosuccinate lyase 7 460 1.2E-155 T 23-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Mlab_0576 536262abe449843d055c00878d913db4 492 Gene3D G3DSA:1.10.40.30 364 439 6.5E-153 T 23-10-2018 Mlab_0576 536262abe449843d055c00878d913db4 492 Pfam PF14698 Argininosuccinate lyase C-terminal 367 436 1.5E-14 T 23-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 SUPERFAMILY SSF103491 7 464 1.06E-102 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 Pfam PF10559 Plug domain of Sec61p 39 72 9.0E-12 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 PIRSF PIRSF004557 5 478 1.7E-99 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 Pfam PF00344 SecY translocase 73 457 1.6E-72 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 28 468 2.3E-91 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 PRINTS PR00303 Preprotein translocase SecY subunit signature 280 299 1.2E-9 T 23-10-2018 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 PRINTS PR00303 Preprotein translocase SecY subunit signature 31 49 1.2E-9 T 23-10-2018 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 PRINTS PR00303 Preprotein translocase SecY subunit signature 177 200 1.2E-9 T 23-10-2018 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 PRINTS PR00303 Preprotein translocase SecY subunit signature 151 176 1.2E-9 T 23-10-2018 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 Hamap MF_01465 Protein translocase subunit SecY [secY]. 18 473 21.313 T 23-10-2018 IPR026593 Protein translocase subunit SecY Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 ProSitePatterns PS00756 Protein secY signature 2. 170 187 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_0104 3e58ba387613a3e6dceaa35f71f725dd 479 Gene3D G3DSA:1.10.3370.10 5 478 9.9E-151 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_1719 946f8ef566ecaeca33e894d4957ebfc7 259 SUPERFAMILY SSF52540 3 230 2.66E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1719 946f8ef566ecaeca33e894d4957ebfc7 259 Pfam PF00005 ABC transporter 21 169 4.6E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1719 946f8ef566ecaeca33e894d4957ebfc7 259 SMART SM00382 29 216 1.2E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1719 946f8ef566ecaeca33e894d4957ebfc7 259 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1719 946f8ef566ecaeca33e894d4957ebfc7 259 Gene3D G3DSA:3.40.50.300 3 257 7.5E-62 T 23-10-2018 Mlab_1704 a9e25a3716fe3c8ec9b92815d4543d46 154 Gene3D G3DSA:2.40.50.140 86 154 1.8E-16 T 23-10-2018 Mlab_1704 a9e25a3716fe3c8ec9b92815d4543d46 154 SUPERFAMILY SSF141322 89 154 1.05E-7 T 23-10-2018 Mlab_1704 a9e25a3716fe3c8ec9b92815d4543d46 154 Pfam PF01957 NfeD-like C-terminal, partner-binding 15 153 8.1E-23 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain Mlab_1567 320c9b46b7f569610ec67c5d656d4e80 411 SUPERFAMILY SSF55120 290 403 6.47E-11 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_1567 320c9b46b7f569610ec67c5d656d4e80 411 Pfam PF02926 THUMP domain 75 160 1.8E-6 T 23-10-2018 IPR004114 THUMP domain GO:0003723 Mlab_1567 320c9b46b7f569610ec67c5d656d4e80 411 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 7 403 2.3E-130 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 Mlab_1567 320c9b46b7f569610ec67c5d656d4e80 411 Gene3D G3DSA:3.30.70.2510 161 294 3.7E-32 T 23-10-2018 Mlab_1567 320c9b46b7f569610ec67c5d656d4e80 411 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 6 404 49.522 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 Mlab_1567 320c9b46b7f569610ec67c5d656d4e80 411 Gene3D G3DSA:3.30.70.3190 295 403 3.8E-28 T 23-10-2018 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 SUPERFAMILY SSF89095 468 605 2.22E-14 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 Pfam PF02938 GAD domain 284 375 5.6E-11 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 168 182 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 SUPERFAMILY SSF55261 265 389 1.13E-42 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 1 607 2.6E-226 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 273 391 3.0E-42 T 23-10-2018 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 Pfam PF02934 GatB/GatE catalytic domain 9 430 1.2E-60 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 SMART SM00845 467 605 9.8E-17 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 SUPERFAMILY SSF55931 2 433 7.19E-87 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 Pfam PF02637 GatB domain 468 605 7.0E-12 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 609 288.404 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 Gene3D G3DSA:1.10.150.380 436 530 1.2E-18 T 23-10-2018 Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 Gene3D G3DSA:1.10.10.410 547 606 3.9E-9 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal Mlab_0578 7128cf6f52ee2ee43024664f2e6a2543 609 Gene3D G3DSA:3.30.1360.30 265 389 1.3E-43 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 Mlab_1406 d379b13784acdbef20f7c39c078493ef 123 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 29 102 2.4E-32 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Mlab_1406 d379b13784acdbef20f7c39c078493ef 123 Gene3D G3DSA:3.10.20.400 4 93 1.4E-37 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 Mlab_1406 d379b13784acdbef20f7c39c078493ef 123 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 3 106 29.443 T 23-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Mlab_1406 d379b13784acdbef20f7c39c078493ef 123 SUPERFAMILY SSF141734 11 110 1.57E-45 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 Mlab_1406 d379b13784acdbef20f7c39c078493ef 123 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 52 105 2.0E-17 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Mlab_0962 d57f6a74b3a6c0894b27da1d878f2754 157 Gene3D G3DSA:3.40.630.30 2 156 1.5E-36 T 23-10-2018 Mlab_0962 d57f6a74b3a6c0894b27da1d878f2754 157 Pfam PF13302 Acetyltransferase (GNAT) domain 4 139 4.2E-27 T 23-10-2018 IPR000182 GNAT domain Mlab_0962 d57f6a74b3a6c0894b27da1d878f2754 157 SUPERFAMILY SSF55729 3 148 2.05E-34 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_1116 44620d39e42532cb44642188cb749034 249 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 249 3.6E-121 T 23-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 Mlab_1116 44620d39e42532cb44642188cb749034 249 Gene3D G3DSA:3.40.50.300 1 247 8.3E-64 T 23-10-2018 Mlab_1116 44620d39e42532cb44642188cb749034 249 SMART SM00382 29 229 6.5E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1116 44620d39e42532cb44642188cb749034 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1116 44620d39e42532cb44642188cb749034 249 SUPERFAMILY SSF52540 4 236 8.57E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1116 44620d39e42532cb44642188cb749034 249 Pfam PF00005 ABC transporter 21 173 3.8E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1326 714519d0a8221b86ceecbcd252b8c63f 545 Gene3D G3DSA:3.40.50.2030 367 534 1.7E-61 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1326 714519d0a8221b86ceecbcd252b8c63f 545 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 532 3.6E-190 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1326 714519d0a8221b86ceecbcd252b8c63f 545 Gene3D G3DSA:1.20.1270.20 1 134 7.8E-29 T 23-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1326 714519d0a8221b86ceecbcd252b8c63f 545 Pfam PF03063 Prismane/CO dehydrogenase family 1 531 4.7E-146 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1326 714519d0a8221b86ceecbcd252b8c63f 545 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 536 19.657 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1326 714519d0a8221b86ceecbcd252b8c63f 545 SUPERFAMILY SSF56821 1 533 1.16E-171 T 23-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 Mlab_1326 714519d0a8221b86ceecbcd252b8c63f 545 Gene3D G3DSA:1.20.1270.20 135 216 1.6E-18 T 23-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1326 714519d0a8221b86ceecbcd252b8c63f 545 Gene3D G3DSA:3.40.50.2030 218 366 2.3E-58 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1326 714519d0a8221b86ceecbcd252b8c63f 545 PIRSF PIRSF000076 1 536 2.8E-206 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1584 9d2924e173f1760b2cd915eaab1b3ad8 81 SUPERFAMILY SSF103456 23 79 2.88E-15 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_1584 9d2924e173f1760b2cd915eaab1b3ad8 81 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 31 80 1.3E-6 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_1584 9d2924e173f1760b2cd915eaab1b3ad8 81 Hamap MF_00422 Protein translocase subunit SecE [secE]. 27 80 11.021 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_1584 9d2924e173f1760b2cd915eaab1b3ad8 81 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 28 79 5.8E-17 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_1584 9d2924e173f1760b2cd915eaab1b3ad8 81 Gene3D G3DSA:1.20.5.820 19 81 2.4E-18 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Mlab_1141 bfbcf4ccb9bd0cefbe427e25bcd79a5c 424 SUPERFAMILY SSF75304 13 423 3.66E-143 T 23-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Mlab_1141 bfbcf4ccb9bd0cefbe427e25bcd79a5c 424 Gene3D G3DSA:3.90.1300.10 2 424 3.8E-172 T 23-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Mlab_1141 bfbcf4ccb9bd0cefbe427e25bcd79a5c 424 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 1 422 82.01 T 23-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Mlab_1141 bfbcf4ccb9bd0cefbe427e25bcd79a5c 424 ProSitePatterns PS00571 Amidases signature. 103 134 - T 23-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 Mlab_1141 bfbcf4ccb9bd0cefbe427e25bcd79a5c 424 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 423 4.3E-170 T 23-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Mlab_1141 bfbcf4ccb9bd0cefbe427e25bcd79a5c 424 Pfam PF01425 Amidase 15 414 1.2E-140 T 23-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Mlab_0071 729a91c089f56d211a70dad7dbe926c6 161 Gene3D G3DSA:1.10.260.40 3 72 6.4E-8 T 23-10-2018 Mlab_0071 729a91c089f56d211a70dad7dbe926c6 161 SUPERFAMILY SSF47413 11 64 3.66E-8 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Mlab_0071 729a91c089f56d211a70dad7dbe926c6 161 SMART SM00530 14 68 2.0E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_0071 729a91c089f56d211a70dad7dbe926c6 161 Pfam PF01381 Helix-turn-helix 17 62 9.0E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_0002 be994201fe02db01f7fcba89d04a617f 163 SUPERFAMILY SSF54909 64 144 5.9E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel Mlab_0002 be994201fe02db01f7fcba89d04a617f 163 Pfam PF13404 AsnC-type helix-turn-helix domain 1 40 1.3E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Mlab_0002 be994201fe02db01f7fcba89d04a617f 163 Pfam PF01037 Lrp/AsnC ligand binding domain 71 142 8.3E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Mlab_0002 be994201fe02db01f7fcba89d04a617f 163 Gene3D G3DSA:1.10.10.10 1 53 2.2E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0002 be994201fe02db01f7fcba89d04a617f 163 SUPERFAMILY SSF46785 1 60 1.18E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0002 be994201fe02db01f7fcba89d04a617f 163 SMART SM00344 1 111 2.4E-20 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Mlab_0002 be994201fe02db01f7fcba89d04a617f 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.2E-7 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Mlab_0002 be994201fe02db01f7fcba89d04a617f 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.2E-7 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Mlab_0002 be994201fe02db01f7fcba89d04a617f 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.2E-7 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Mlab_0002 be994201fe02db01f7fcba89d04a617f 163 Gene3D G3DSA:3.30.70.920 54 148 1.7E-20 T 23-10-2018 Mlab_0111 a80a935e5a708be2b41bcda33bfb2a1f 168 SUPERFAMILY SSF57802 134 165 7.07E-8 T 23-10-2018 Mlab_0111 a80a935e5a708be2b41bcda33bfb2a1f 168 Pfam PF02915 Rubrerythrin 10 121 6.0E-18 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 Mlab_0111 a80a935e5a708be2b41bcda33bfb2a1f 168 SUPERFAMILY SSF47240 5 130 2.29E-33 T 23-10-2018 IPR009078 Ferritin-like superfamily Mlab_0111 a80a935e5a708be2b41bcda33bfb2a1f 168 Gene3D G3DSA:2.20.28.10 130 168 2.2E-11 T 23-10-2018 Mlab_0111 a80a935e5a708be2b41bcda33bfb2a1f 168 Gene3D G3DSA:1.20.1260.10 2 129 7.1E-40 T 23-10-2018 IPR012347 Ferritin-like Mlab_0015 cf5e4a9d624f8ac662de869d9f267d4f 455 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 41 66 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 Mlab_0015 cf5e4a9d624f8ac662de869d9f267d4f 455 TIGRFAM TIGR03295 frhA: coenzyme F420 hydrogenase, subunit alpha 1 454 1.2E-191 T 23-10-2018 IPR017682 Coenzyme F420 hydrogenase, subunit alpha GO:0016151|GO:0050454|GO:0050660|GO:0051536|GO:0055114 KEGG: 00680+1.12.98.1|MetaCyc: PWY-5207 Mlab_0015 cf5e4a9d624f8ac662de869d9f267d4f 455 SUPERFAMILY SSF56762 3 438 1.44E-93 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0015 cf5e4a9d624f8ac662de869d9f267d4f 455 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 429 438 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 Mlab_0015 cf5e4a9d624f8ac662de869d9f267d4f 455 Gene3D G3DSA:1.10.645.10 1 438 1.8E-123 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0015 cf5e4a9d624f8ac662de869d9f267d4f 455 Pfam PF00374 Nickel-dependent hydrogenase 41 109 1.1E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 Mlab_0015 cf5e4a9d624f8ac662de869d9f267d4f 455 Pfam PF00374 Nickel-dependent hydrogenase 329 438 8.1E-10 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 Mlab_0158 6fe7b01325f529ad8b9a58541b5e1a1c 110 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 23-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 Mlab_0158 6fe7b01325f529ad8b9a58541b5e1a1c 110 PRINTS PR00340 P-II protein signature 83 103 4.9E-32 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Mlab_0158 6fe7b01325f529ad8b9a58541b5e1a1c 110 PRINTS PR00340 P-II protein signature 52 75 4.9E-32 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Mlab_0158 6fe7b01325f529ad8b9a58541b5e1a1c 110 PRINTS PR00340 P-II protein signature 2 17 4.9E-32 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Mlab_0158 6fe7b01325f529ad8b9a58541b5e1a1c 110 PRINTS PR00340 P-II protein signature 23 41 4.9E-32 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Mlab_0158 6fe7b01325f529ad8b9a58541b5e1a1c 110 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.1E-33 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Mlab_0158 6fe7b01325f529ad8b9a58541b5e1a1c 110 Gene3D G3DSA:3.30.70.120 1 109 1.1E-39 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Mlab_0158 6fe7b01325f529ad8b9a58541b5e1a1c 110 SUPERFAMILY SSF54913 1 107 2.7E-36 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Mlab_0158 6fe7b01325f529ad8b9a58541b5e1a1c 110 SMART SM00938 4 105 2.3E-49 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Mlab_1340 9a4177a363003612f0b0f78017c8812c 233 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 8 93 7.9E-21 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal Mlab_1340 9a4177a363003612f0b0f78017c8812c 233 SUPERFAMILY SSF109728 82 154 6.67E-24 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily Mlab_1340 9a4177a363003612f0b0f78017c8812c 233 Gene3D G3DSA:3.30.70.240 162 233 4.0E-22 T 23-10-2018 Mlab_1340 9a4177a363003612f0b0f78017c8812c 233 SUPERFAMILY SSF89895 2 85 1.44E-21 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily Mlab_1340 9a4177a363003612f0b0f78017c8812c 233 Gene3D G3DSA:1.10.10.900 87 161 2.5E-30 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily Mlab_1340 9a4177a363003612f0b0f78017c8812c 233 Pfam PF09377 SBDS protein C-terminal domain 100 216 8.0E-18 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 Mlab_1340 9a4177a363003612f0b0f78017c8812c 233 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 1 232 1.6E-81 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 Mlab_1340 9a4177a363003612f0b0f78017c8812c 233 Gene3D G3DSA:3.30.1250.10 7 86 2.7E-25 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily Mlab_1340 9a4177a363003612f0b0f78017c8812c 233 SUPERFAMILY SSF54980 156 230 1.01E-17 T 23-10-2018 IPR035647 EF-G domain III/V-like Mlab_0047 0db3bf6aa0b9e3a72ea06103d1620691 84 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0047 0db3bf6aa0b9e3a72ea06103d1620691 84 Pfam PF00037 4Fe-4S binding domain 28 50 1.3E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0047 0db3bf6aa0b9e3a72ea06103d1620691 84 SUPERFAMILY SSF54862 12 82 3.91E-17 T 23-10-2018 Mlab_0047 0db3bf6aa0b9e3a72ea06103d1620691 84 Gene3D G3DSA:3.30.70.20 8 52 2.0E-5 T 23-10-2018 Mlab_0047 0db3bf6aa0b9e3a72ea06103d1620691 84 Gene3D G3DSA:3.30.70.20 53 84 1.2E-5 T 23-10-2018 Mlab_0047 0db3bf6aa0b9e3a72ea06103d1620691 84 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 11 83 1.4E-27 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR00418 DNA topoisomerase II family signature 287 300 7.2E-68 T 23-10-2018 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR00418 DNA topoisomerase II family signature 583 599 7.2E-68 T 23-10-2018 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR00418 DNA topoisomerase II family signature 542 554 7.2E-68 T 23-10-2018 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR00418 DNA topoisomerase II family signature 522 539 7.2E-68 T 23-10-2018 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR00418 DNA topoisomerase II family signature 69 82 7.2E-68 T 23-10-2018 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR00418 DNA topoisomerase II family signature 504 520 7.2E-68 T 23-10-2018 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR00418 DNA topoisomerase II family signature 34 49 7.2E-68 T 23-10-2018 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR00418 DNA topoisomerase II family signature 112 126 7.2E-68 T 23-10-2018 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR00418 DNA topoisomerase II family signature 438 452 7.2E-68 T 23-10-2018 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 190 3.7E-20 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 SUPERFAMILY SSF54211 238 409 4.36E-54 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 Pfam PF00204 DNA gyrase B 238 408 4.5E-61 T 23-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 5 651 1.6E-284 T 23-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 579 640 6.7E-27 T 23-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 Gene3D G3DSA:3.30.565.10 1 236 6.3E-87 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 SMART SM00433 34 644 0.0 T 23-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 2 651 87.247 T 23-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 Gene3D G3DSA:3.40.50.670 417 651 4.3E-104 T 23-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR01159 DNA gyrase subunit B signature 620 636 2.9E-72 T 23-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR01159 DNA gyrase subunit B signature 604 616 2.9E-72 T 23-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR01159 DNA gyrase subunit B signature 378 392 2.9E-72 T 23-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR01159 DNA gyrase subunit B signature 237 259 2.9E-72 T 23-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR01159 DNA gyrase subunit B signature 488 497 2.9E-72 T 23-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR01159 DNA gyrase subunit B signature 261 279 2.9E-72 T 23-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR01159 DNA gyrase subunit B signature 330 346 2.9E-72 T 23-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR01159 DNA gyrase subunit B signature 198 213 2.9E-72 T 23-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR01159 DNA gyrase subunit B signature 5 15 2.9E-72 T 23-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR01159 DNA gyrase subunit B signature 213 226 2.9E-72 T 23-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 PRINTS PR01159 DNA gyrase subunit B signature 392 412 2.9E-72 T 23-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 SUPERFAMILY SSF55874 4 235 2.49E-67 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 Gene3D G3DSA:3.30.230.10 237 416 7.5E-68 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 SMART SM00387 30 193 3.8E-26 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 SUPERFAMILY SSF56719 412 644 8.89E-85 T 23-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 Pfam PF01751 Toprim domain 437 548 3.0E-18 T 23-10-2018 IPR006171 TOPRIM domain Mlab_0412 a14af090b5e3121bfbb9d6d47b29f742 651 ProSitePatterns PS00177 DNA topoisomerase II signature. 440 448 - T 23-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Mlab_1082 7e310f8ec5e4c352fe28f2627f8cdf54 335 Pfam PF01888 CbiD 41 271 5.2E-41 T 23-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Mlab_1082 7e310f8ec5e4c352fe28f2627f8cdf54 335 Gene3D G3DSA:3.30.2110.10 43 206 2.9E-33 T 23-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Mlab_1082 7e310f8ec5e4c352fe28f2627f8cdf54 335 SUPERFAMILY SSF111342 2 288 3.27E-49 T 23-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Mlab_1082 7e310f8ec5e4c352fe28f2627f8cdf54 335 Gene3D G3DSA:3.40.50.10720 207 298 5.9E-19 T 23-10-2018 Mlab_0492 a6a065b5ba834e1ab97e0f6e4a87ea11 236 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 234 31.019 T 23-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 Mlab_0492 a6a065b5ba834e1ab97e0f6e4a87ea11 236 SUPERFAMILY SSF51366 1 233 2.29E-66 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_0492 a6a065b5ba834e1ab97e0f6e4a87ea11 236 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 231 1.5E-70 T 23-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 Mlab_0492 a6a065b5ba834e1ab97e0f6e4a87ea11 236 Gene3D G3DSA:3.20.20.70 1 236 5.5E-80 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0492 a6a065b5ba834e1ab97e0f6e4a87ea11 236 Pfam PF00977 Histidine biosynthesis protein 3 227 5.4E-69 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Mlab_0969 7e6a5ce7825eacf4a737c2bf5defd3b3 63 Gene3D G3DSA:3.10.20.30 4 63 1.0E-8 T 23-10-2018 IPR012675 Beta-grasp domain superfamily Mlab_0969 7e6a5ce7825eacf4a737c2bf5defd3b3 63 SUPERFAMILY SSF54285 6 63 3.66E-6 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Mlab_0331 25b71bb15b6eed5d85ca2f7fea1b1013 165 SUPERFAMILY SSF46785 29 162 1.82E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0331 25b71bb15b6eed5d85ca2f7fea1b1013 165 Gene3D G3DSA:1.10.10.10 29 164 3.9E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0331 25b71bb15b6eed5d85ca2f7fea1b1013 165 Pfam PF01047 MarR family 57 112 3.3E-11 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0331 25b71bb15b6eed5d85ca2f7fea1b1013 165 SMART SM00347 48 148 1.2E-18 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0331 25b71bb15b6eed5d85ca2f7fea1b1013 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 1.4E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0331 25b71bb15b6eed5d85ca2f7fea1b1013 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 1.4E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0664 0089d8e5d3d405beaf595f8d42846f8e 580 Pfam PF13522 Glutamine amidotransferase domain 52 188 1.6E-21 T 23-10-2018 Mlab_0664 0089d8e5d3d405beaf595f8d42846f8e 580 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 580 2.1E-208 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 Mlab_0664 0089d8e5d3d405beaf595f8d42846f8e 580 SUPERFAMILY SSF56235 2 219 5.49E-65 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Mlab_0664 0089d8e5d3d405beaf595f8d42846f8e 580 Pfam PF01380 SIS domain 275 400 1.6E-24 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Mlab_0664 0089d8e5d3d405beaf595f8d42846f8e 580 Pfam PF01380 SIS domain 435 562 1.7E-22 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Mlab_0664 0089d8e5d3d405beaf595f8d42846f8e 580 Gene3D G3DSA:3.40.50.10490 241 579 4.2E-117 T 23-10-2018 Mlab_0664 0089d8e5d3d405beaf595f8d42846f8e 580 Gene3D G3DSA:3.60.20.10 2 232 1.2E-69 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Mlab_0664 0089d8e5d3d405beaf595f8d42846f8e 580 SUPERFAMILY SSF53697 240 580 1.58E-90 T 23-10-2018 Mlab_0664 0089d8e5d3d405beaf595f8d42846f8e 580 Gene3D G3DSA:3.40.50.10490 420 565 4.2E-117 T 23-10-2018 Mlab_1538 9bcefb154f3e0db6756991ad00bb28a7 601 Gene3D G3DSA:1.20.81.30 399 512 2.0E-6 T 23-10-2018 Mlab_1538 9bcefb154f3e0db6756991ad00bb28a7 601 Pfam PF00482 Type II secretion system (T2SS), protein F 117 239 1.7E-15 T 23-10-2018 IPR018076 Type II secretion system F domain Mlab_1538 9bcefb154f3e0db6756991ad00bb28a7 601 Pfam PF00482 Type II secretion system (T2SS), protein F 407 524 2.1E-10 T 23-10-2018 IPR018076 Type II secretion system F domain Mlab_1197 747e4052e1708bb592b4bc219c0994b4 173 Gene3D G3DSA:3.90.75.20 30 123 1.1E-8 T 23-10-2018 Mlab_1197 747e4052e1708bb592b4bc219c0994b4 173 Pfam PF13392 HNH endonuclease 91 118 2.6E-8 T 23-10-2018 IPR003615 HNH nuclease Mlab_1197 747e4052e1708bb592b4bc219c0994b4 173 SUPERFAMILY SSF54060 27 118 1.29E-12 T 23-10-2018 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 PIRSF PIRSF500175 3 409 1.4E-152 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 SUPERFAMILY SSF53774 65 405 4.58E-102 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 PRINTS PR00139 Asparaginase/glutaminase family signature 149 167 9.5E-16 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 PRINTS PR00139 Asparaginase/glutaminase family signature 329 347 9.5E-16 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 PRINTS PR00139 Asparaginase/glutaminase family signature 73 84 9.5E-16 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 Gene3D G3DSA:3.40.50.1170 66 278 3.5E-69 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 9 408 42.407 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 20 405 1.5E-147 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 Gene3D G3DSA:3.40.50.40 279 409 1.1E-41 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 PIRSF PIRSF001220 67 403 3.9E-91 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 71 404 2.2E-122 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 SUPERFAMILY SSF141300 2 45 1.96E-9 T 23-10-2018 IPR037222 GatD, N-terminal Mlab_0577 187c42327b022c71a4c4f7db13113359 411 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 150 160 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 SMART SM00870 72 392 1.8E-135 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 75 83 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 Mlab_0577 187c42327b022c71a4c4f7db13113359 411 Pfam PF00710 Asparaginase, N-terminal 74 254 5.9E-55 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 Mlab_0098 5cb8b02f81fa1d8aee54318dfcf153a9 144 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 1 122 4.0E-34 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0098 5cb8b02f81fa1d8aee54318dfcf153a9 144 SMART SM01393 17 122 1.5E-47 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0098 5cb8b02f81fa1d8aee54318dfcf153a9 144 Pfam PF01655 Ribosomal protein L32 18 122 2.1E-31 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0098 5cb8b02f81fa1d8aee54318dfcf153a9 144 SUPERFAMILY SSF52042 11 126 9.15E-34 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1627 cb846b6a93dd03af5f3a14b4b0eaefef 347 SUPERFAMILY SSF53901 2 167 4.61E-35 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 Mlab_1627 cb846b6a93dd03af5f3a14b4b0eaefef 347 Gene3D G3DSA:3.40.47.10 1 344 3.5E-76 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 Mlab_1627 cb846b6a93dd03af5f3a14b4b0eaefef 347 Hamap MF_01409 UPF0219 protein . 1 347 57.688 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related Mlab_1627 cb846b6a93dd03af5f3a14b4b0eaefef 347 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 1 347 2.7E-167 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related Mlab_1627 cb846b6a93dd03af5f3a14b4b0eaefef 347 SUPERFAMILY SSF53901 169 344 6.81E-45 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 Mlab_1627 cb846b6a93dd03af5f3a14b4b0eaefef 347 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2 168 2.9E-6 T 23-10-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 Mlab_1627 cb846b6a93dd03af5f3a14b4b0eaefef 347 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 221 298 3.6E-8 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Mlab_0088 3803534e48da7d94f4b28eaaefe18d41 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 8 62 2.9E-12 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0088 3803534e48da7d94f4b28eaaefe18d41 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0088 3803534e48da7d94f4b28eaaefe18d41 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 4 64 12.843 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0088 3803534e48da7d94f4b28eaaefe18d41 66 SUPERFAMILY SSF46561 3 65 2.62E-15 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0088 3803534e48da7d94f4b28eaaefe18d41 66 Gene3D G3DSA:1.10.287.310 1 66 1.4E-21 T 23-10-2018 Mlab_0088 3803534e48da7d94f4b28eaaefe18d41 66 Pfam PF00831 Ribosomal L29 protein 7 64 7.6E-15 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0189 06f79a6fbe23fafb782a1319735a04a0 92 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 92 8.6E-21 T 23-10-2018 IPR010038 MoaD, archaeal-type Mlab_0189 06f79a6fbe23fafb782a1319735a04a0 92 Gene3D G3DSA:3.10.20.30 1 92 4.2E-26 T 23-10-2018 IPR012675 Beta-grasp domain superfamily Mlab_0189 06f79a6fbe23fafb782a1319735a04a0 92 SUPERFAMILY SSF54285 1 92 5.05E-22 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Mlab_0189 06f79a6fbe23fafb782a1319735a04a0 92 Pfam PF02597 ThiS family 5 92 8.0E-17 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 SUPERFAMILY SSF56655 10 271 3.27E-74 T 23-10-2018 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 19 146 1.4E-36 T 23-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 PIRSF PIRSF500210 3 273 1.9E-82 T 23-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 Gene3D G3DSA:3.30.540.10 3 148 4.6E-40 T 23-10-2018 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 1 273 28.646 T 23-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 132 155 5.2E-23 T 23-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 249 273 5.2E-23 T 23-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 33 59 5.2E-23 T 23-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 102 125 5.2E-23 T 23-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 PIRSF PIRSF000904 2 273 4.3E-82 T 23-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 215 227 - T 23-10-2018 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Mlab_1328 9184351a12f2b2c56e4968084283ea32 273 Gene3D G3DSA:3.40.190.80 154 273 2.7E-36 T 23-10-2018 Mlab_1582 b6ec7f145bd221531b1ef855965c00ad 157 Gene3D G3DSA:2.10.260.30 1 67 3.3E-26 T 23-10-2018 Mlab_1582 b6ec7f145bd221531b1ef855965c00ad 157 SMART SM00649 5 136 5.6E-56 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Mlab_1582 b6ec7f145bd221531b1ef855965c00ad 157 SUPERFAMILY SSF46906 64 136 3.66E-22 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily Mlab_1582 b6ec7f145bd221531b1ef855965c00ad 157 Pfam PF00298 Ribosomal protein L11, RNA binding domain 69 135 2.0E-21 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 Mlab_1582 b6ec7f145bd221531b1ef855965c00ad 157 Gene3D G3DSA:1.10.10.250 71 157 6.0E-33 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily Mlab_1582 b6ec7f145bd221531b1ef855965c00ad 157 ProSitePatterns PS00359 Ribosomal protein L11 signature. 122 137 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1582 b6ec7f145bd221531b1ef855965c00ad 157 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 60 1.6E-21 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal Mlab_1582 b6ec7f145bd221531b1ef855965c00ad 157 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 137 27.203 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Mlab_1582 b6ec7f145bd221531b1ef855965c00ad 157 SUPERFAMILY SSF54747 4 80 7.19E-24 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily Mlab_0984 7e66f803b1347da47eb1095379feddbf 262 Pfam PF14338 Mrr N-terminal domain 7 91 2.2E-14 T 23-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain Mlab_0845 47c0af6ca313b81b136500230dd4bf87 266 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 4 249 3.8E-75 T 23-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Mlab_0845 47c0af6ca313b81b136500230dd4bf87 266 Pfam PF08543 Phosphomethylpyrimidine kinase 11 249 3.7E-74 T 23-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 Mlab_0845 47c0af6ca313b81b136500230dd4bf87 266 Gene3D G3DSA:3.40.1190.20 1 265 4.3E-79 T 23-10-2018 IPR029056 Ribokinase-like Mlab_0845 47c0af6ca313b81b136500230dd4bf87 266 SUPERFAMILY SSF53613 3 253 1.48E-64 T 23-10-2018 IPR029056 Ribokinase-like Mlab_1300 387a8058ffaec2c88f7e198823712159 62 Gene3D G3DSA:2.20.25.100 8 62 2.3E-25 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily Mlab_1300 387a8058ffaec2c88f7e198823712159 62 SUPERFAMILY SSF57829 9 61 2.75E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Mlab_1300 387a8058ffaec2c88f7e198823712159 62 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 2 61 20.454 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1300 387a8058ffaec2c88f7e198823712159 62 Pfam PF01667 Ribosomal protein S27 8 58 5.1E-25 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0856 359aa97efd4b37295cb49429c635b4a5 649 Pfam PF07664 Ferrous iron transport protein B C terminus 438 490 1.9E-22 T 23-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 Mlab_0856 359aa97efd4b37295cb49429c635b4a5 649 Pfam PF02421 Ferrous iron transport protein B 4 161 1.9E-61 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 Mlab_0856 359aa97efd4b37295cb49429c635b4a5 649 Gene3D G3DSA:3.40.50.300 4 193 4.6E-39 T 23-10-2018 Mlab_0856 359aa97efd4b37295cb49429c635b4a5 649 Pfam PF07670 Nucleoside recognition 335 427 1.2E-15 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Mlab_0856 359aa97efd4b37295cb49429c635b4a5 649 Pfam PF07670 Nucleoside recognition 495 618 2.4E-27 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Mlab_0856 359aa97efd4b37295cb49429c635b4a5 649 SUPERFAMILY SSF52540 4 167 6.6E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0856 359aa97efd4b37295cb49429c635b4a5 649 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 614 2.8E-192 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 Mlab_1396 34c9d7db8b26713a9f17d6cafbccb00a 255 Pfam PF00218 Indole-3-glycerol phosphate synthase 29 251 2.2E-66 T 23-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 Mlab_1396 34c9d7db8b26713a9f17d6cafbccb00a 255 SUPERFAMILY SSF51366 2 252 6.12E-67 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_1396 34c9d7db8b26713a9f17d6cafbccb00a 255 Gene3D G3DSA:3.20.20.70 1 253 7.7E-79 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0745 c8fb04dab097fdc6bbfe9b4fd9bed144 331 Gene3D G3DSA:3.40.640.10 38 238 2.0E-77 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_0745 c8fb04dab097fdc6bbfe9b4fd9bed144 331 Pfam PF00155 Aminotransferase class I and II 57 326 1.4E-35 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Mlab_0745 c8fb04dab097fdc6bbfe9b4fd9bed144 331 Gene3D G3DSA:3.90.1150.10 26 327 2.0E-77 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_0745 c8fb04dab097fdc6bbfe9b4fd9bed144 331 SUPERFAMILY SSF53383 19 330 6.95E-61 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_0230 123c5986c2bc6ddb9641a7aa3cc5db87 343 Pfam PF04055 Radical SAM superfamily 110 262 4.5E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0230 123c5986c2bc6ddb9641a7aa3cc5db87 343 SMART SM00729 105 303 1.3E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_0230 123c5986c2bc6ddb9641a7aa3cc5db87 343 SUPERFAMILY SSF102114 102 330 1.57E-24 T 23-10-2018 Mlab_0230 123c5986c2bc6ddb9641a7aa3cc5db87 343 Gene3D G3DSA:3.20.20.70 98 300 4.3E-14 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0999 cf705b71b738a85553d7fbb4393edc6a 180 SUPERFAMILY SSF47240 5 136 3.95E-38 T 23-10-2018 IPR009078 Ferritin-like superfamily Mlab_0999 cf705b71b738a85553d7fbb4393edc6a 180 SUPERFAMILY SSF57802 139 179 6.16E-11 T 23-10-2018 Mlab_0999 cf705b71b738a85553d7fbb4393edc6a 180 Gene3D G3DSA:1.20.1260.10 1 135 2.7E-49 T 23-10-2018 IPR012347 Ferritin-like Mlab_0999 cf705b71b738a85553d7fbb4393edc6a 180 Gene3D G3DSA:2.20.28.10 136 180 9.6E-19 T 23-10-2018 Mlab_0999 cf705b71b738a85553d7fbb4393edc6a 180 Pfam PF02915 Rubrerythrin 12 128 2.0E-22 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 Mlab_0059 5b7897c8fea088e469f01c64395aa6f1 401 Gene3D G3DSA:1.10.3210.10 1 252 7.3E-78 T 23-10-2018 Mlab_0059 5b7897c8fea088e469f01c64395aa6f1 401 SUPERFAMILY SSF109604 3 387 3.01E-91 T 23-10-2018 Mlab_0059 5b7897c8fea088e469f01c64395aa6f1 401 Pfam PF01966 HD domain 51 163 5.1E-13 T 23-10-2018 IPR006674 HD domain Mlab_0059 5b7897c8fea088e469f01c64395aa6f1 401 SMART SM00471 47 170 3.6E-14 T 23-10-2018 IPR003607 HD/PDEase domain Mlab_0218 a988462ab499180054263c9b696b0b31 316 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 3 301 1.5E-86 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 Mlab_0218 a988462ab499180054263c9b696b0b31 316 Gene3D G3DSA:3.40.50.11850 94 199 1.5E-32 T 23-10-2018 Mlab_0218 a988462ab499180054263c9b696b0b31 316 Gene3D G3DSA:3.40.50.11840 3 92 2.0E-23 T 23-10-2018 Mlab_0218 a988462ab499180054263c9b696b0b31 316 Gene3D G3DSA:3.40.50.11860 204 301 4.4E-29 T 23-10-2018 Mlab_0218 a988462ab499180054263c9b696b0b31 316 Pfam PF01866 Putative diphthamide synthesis protein 23 309 1.3E-74 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 Mlab_0218 a988462ab499180054263c9b696b0b31 316 PIRSF PIRSF004967 1 314 3.3E-74 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 Mlab_0218 a988462ab499180054263c9b696b0b31 316 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 15 314 1.9E-109 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 Gene3D G3DSA:1.20.1110.10 52 869 7.2E-272 T 23-10-2018 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 Pfam PF00702 haloacid dehalogenase-like hydrolase 319 636 6.4E-22 T 23-10-2018 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 Pfam PF00122 E1-E2 ATPase 111 302 7.6E-53 T 23-10-2018 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 SUPERFAMILY SSF81653 113 221 5.1E-29 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 Gene3D G3DSA:2.70.150.10 13 225 7.2E-272 T 23-10-2018 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 SUPERFAMILY SSF81665 2 884 3.53E-118 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 Gene3D G3DSA:3.40.50.1000 319 667 7.2E-272 T 23-10-2018 IPR023214 HAD superfamily Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 646 658 2.5E-40 T 23-10-2018 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 552 2.5E-40 T 23-10-2018 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 520 531 2.5E-40 T 23-10-2018 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 322 336 2.5E-40 T 23-10-2018 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 159 173 2.5E-40 T 23-10-2018 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 641 2.5E-40 T 23-10-2018 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 Gene3D G3DSA:3.40.1110.10 332 527 7.2E-272 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 477 495 7.2E-20 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 594 610 7.2E-20 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 622 638 7.2E-20 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 654 679 7.2E-20 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 324 330 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 SMART SM00831 2 74 2.5E-20 T 23-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 592 707 1.2E-35 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 81 343 1.9E-40 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 Pfam PF00690 Cation transporter/ATPase, N-terminus 2 69 2.5E-20 T 23-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 SUPERFAMILY SSF81660 329 500 1.21E-40 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 Pfam PF00689 Cation transporting ATPase, C-terminus 706 877 1.1E-42 T 23-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 Mlab_0725 125238b96acee61dc0f0ea9be39a448f 886 SUPERFAMILY SSF56784 320 726 6.0E-60 T 23-10-2018 IPR036412 HAD-like superfamily Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 136 1.0E-9 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 Pfam PF09239 Topoisomerase VI B subunit, transducer 309 466 4.4E-61 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 SMART SM00387 31 182 9.6E-6 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 SUPERFAMILY SSF46946 230 301 5.0E-9 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 Gene3D G3DSA:1.10.8.50 230 303 1.5E-18 T 23-10-2018 Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 Gene3D G3DSA:3.30.565.10 2 229 6.4E-69 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 SUPERFAMILY SSF54211 309 469 2.73E-51 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 10 488 2.8E-152 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 8 505 29.029 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 308 509 1.0E-76 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 Gene3D G3DSA:3.30.230.10 305 523 2.2E-66 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 PIRSF PIRSF006553 1 565 2.0E-207 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Mlab_0416 8f085a203a56ed64dfe63d26b4dcf137 600 SUPERFAMILY SSF55874 18 220 4.32E-27 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Mlab_0153 5d0bc70a215170c0a0b2f01022b6b147 212 Gene3D G3DSA:3.20.20.70 1 210 1.1E-62 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0153 5d0bc70a215170c0a0b2f01022b6b147 212 SMART SM00934 3 207 1.3E-56 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0153 5d0bc70a215170c0a0b2f01022b6b147 212 SUPERFAMILY SSF51366 3 208 7.54E-53 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_0153 5d0bc70a215170c0a0b2f01022b6b147 212 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 4 207 1.6E-49 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0153 5d0bc70a215170c0a0b2f01022b6b147 212 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 206 1.0E-36 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0153 5d0bc70a215170c0a0b2f01022b6b147 212 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 55 68 - T 23-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0148 84111d65a4d82327f2a52b7606d122f7 165 Gene3D G3DSA:2.30.130.10 80 163 7.2E-26 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 Mlab_0148 84111d65a4d82327f2a52b7606d122f7 165 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 52 158 3.3E-28 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 Mlab_0148 84111d65a4d82327f2a52b7606d122f7 165 Pfam PF09183 Domain of unknown function (DUF1947) 8 72 1.3E-5 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 Mlab_0148 84111d65a4d82327f2a52b7606d122f7 165 SMART SM00359 82 157 1.7E-12 T 23-10-2018 IPR002478 PUA domain GO:0003723 Mlab_0148 84111d65a4d82327f2a52b7606d122f7 165 PIRSF PIRSF005067 1 165 8.4E-42 T 23-10-2018 IPR016437 MCT-1/Tma20 Mlab_0148 84111d65a4d82327f2a52b7606d122f7 165 Pfam PF01472 PUA domain 83 156 2.6E-14 T 23-10-2018 IPR002478 PUA domain GO:0003723 Mlab_0148 84111d65a4d82327f2a52b7606d122f7 165 SUPERFAMILY SSF88697 83 163 4.81E-19 T 23-10-2018 IPR015947 PUA-like superfamily Mlab_0148 84111d65a4d82327f2a52b7606d122f7 165 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 9 163 8.1E-55 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 Mlab_0148 84111d65a4d82327f2a52b7606d122f7 165 Gene3D G3DSA:3.10.450.120 1 77 8.6E-7 T 23-10-2018 Mlab_0483 efe2dcdbbb12a7126dbf39ee918e0e38 95 Pfam PF13237 4Fe-4S dicluster domain 8 74 3.8E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0483 efe2dcdbbb12a7126dbf39ee918e0e38 95 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 15 26 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0483 efe2dcdbbb12a7126dbf39ee918e0e38 95 SUPERFAMILY SSF54862 6 86 1.6E-16 T 23-10-2018 Mlab_0483 efe2dcdbbb12a7126dbf39ee918e0e38 95 Gene3D G3DSA:3.30.70.20 6 82 4.1E-9 T 23-10-2018 Mlab_0194 c85b1dcdd479a6201451693315341acd 226 Gene3D G3DSA:3.40.50.300 4 226 8.6E-72 T 23-10-2018 Mlab_0194 c85b1dcdd479a6201451693315341acd 226 Pfam PF00005 ABC transporter 26 174 6.3E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0194 c85b1dcdd479a6201451693315341acd 226 SMART SM00382 35 222 1.1E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0194 c85b1dcdd479a6201451693315341acd 226 SUPERFAMILY SSF52540 6 225 3.79E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0194 c85b1dcdd479a6201451693315341acd 226 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0239 82c4736454f7ab51d08ec6bd2a5bde8d 194 Gene3D G3DSA:1.10.1060.10 15 132 6.9E-7 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Mlab_0239 82c4736454f7ab51d08ec6bd2a5bde8d 194 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0239 82c4736454f7ab51d08ec6bd2a5bde8d 194 SUPERFAMILY SSF46548 42 121 7.15E-17 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Mlab_0239 82c4736454f7ab51d08ec6bd2a5bde8d 194 Pfam PF13187 4Fe-4S dicluster domain 46 104 1.2E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0239 82c4736454f7ab51d08ec6bd2a5bde8d 194 TIGRFAM TIGR03290 CoB_CoM_SS_C: CoB--CoM heterodisulfide reductase, subunit C 44 185 1.2E-61 T 23-10-2018 IPR017680 CoB--CoM heterodisulphide reductase, subunit C GO:0015948|GO:0051186|GO:0051539|GO:0051912|GO:0055114 Mlab_0768 ac9562eb65c6c98216e07501e45188e4 262 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 19 24 - T 23-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 Mlab_0768 ac9562eb65c6c98216e07501e45188e4 262 SUPERFAMILY SSF53335 1 248 9.79E-54 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0768 ac9562eb65c6c98216e07501e45188e4 262 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 14 28 1.2E-23 T 23-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Mlab_0768 ac9562eb65c6c98216e07501e45188e4 262 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 205 223 1.2E-23 T 23-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Mlab_0768 ac9562eb65c6c98216e07501e45188e4 262 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 228 248 1.2E-23 T 23-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Mlab_0768 ac9562eb65c6c98216e07501e45188e4 262 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 185 202 1.2E-23 T 23-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Mlab_0768 ac9562eb65c6c98216e07501e45188e4 262 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 49 69 1.2E-23 T 23-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Mlab_0768 ac9562eb65c6c98216e07501e45188e4 262 Pfam PF01555 DNA methylase 15 245 2.1E-41 T 23-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 Mlab_0768 ac9562eb65c6c98216e07501e45188e4 262 Gene3D G3DSA:3.40.50.150 1 261 7.4E-55 T 23-10-2018 Mlab_0364 8efd4d80388292bd287a673045e60286 341 PIRSF PIRSF005644 2 341 6.9E-125 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE Mlab_0364 8efd4d80388292bd287a673045e60286 341 Gene3D G3DSA:3.30.1330.10 8 157 5.6E-44 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0364 8efd4d80388292bd287a673045e60286 341 SUPERFAMILY SSF55326 6 157 1.45E-31 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0364 8efd4d80388292bd287a673045e60286 341 Pfam PF02769 AIR synthase related protein, C-terminal domain 168 317 3.2E-33 T 23-10-2018 IPR010918 PurM-like, C-terminal domain Mlab_0364 8efd4d80388292bd287a673045e60286 341 Pfam PF00586 AIR synthase related protein, N-terminal domain 54 154 4.1E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain Mlab_0364 8efd4d80388292bd287a673045e60286 341 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 7 341 1.1E-124 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE Mlab_0364 8efd4d80388292bd287a673045e60286 341 Gene3D G3DSA:3.90.650.10 161 341 1.6E-53 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0364 8efd4d80388292bd287a673045e60286 341 SUPERFAMILY SSF56042 162 335 2.09E-45 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 Gene3D G3DSA:3.40.50.1000 482 619 1.3E-107 T 23-10-2018 IPR023214 HAD superfamily Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 Gene3D G3DSA:3.40.50.1000 324 336 3.1E-96 T 23-10-2018 IPR023214 HAD superfamily Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 Gene3D G3DSA:1.20.1110.10 620 828 1.3E-107 T 23-10-2018 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 Pfam PF00689 Cation transporting ATPase, C-terminus 658 830 1.0E-33 T 23-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 SUPERFAMILY SSF81660 337 481 1.11E-9 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 474 485 7.7E-37 T 23-10-2018 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 165 179 7.7E-37 T 23-10-2018 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 496 506 7.7E-37 T 23-10-2018 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 574 593 7.7E-37 T 23-10-2018 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 598 610 7.7E-37 T 23-10-2018 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 327 341 7.7E-37 T 23-10-2018 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 SUPERFAMILY SSF81653 118 225 1.57E-25 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 Gene3D G3DSA:2.70.150.10 20 230 3.1E-96 T 23-10-2018 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 SUPERFAMILY SSF81665 7 833 3.4E-98 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 606 631 3.2E-16 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 574 590 3.2E-16 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 443 461 3.2E-16 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 546 562 3.2E-16 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 329 335 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 Pfam PF00702 haloacid dehalogenase-like hydrolase 324 588 1.2E-23 T 23-10-2018 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 Gene3D G3DSA:3.40.1110.10 465 481 1.3E-107 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 Gene3D G3DSA:3.40.1110.10 337 388 3.1E-96 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 Pfam PF00690 Cation transporter/ATPase, N-terminus 8 73 9.4E-11 T 23-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 SUPERFAMILY SSF56784 325 672 5.89E-50 T 23-10-2018 IPR036412 HAD-like superfamily Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 SMART SM00831 6 80 7.9E-11 T 23-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 544 663 8.4E-35 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 86 351 1.4E-36 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 Pfam PF00122 E1-E2 ATPase 114 306 4.8E-50 T 23-10-2018 Mlab_0985 8ba8df1b76204e8203a587bb15afa221 844 Gene3D G3DSA:1.20.1110.10 58 323 3.1E-96 T 23-10-2018 Mlab_0436 acee0be7beaa150309500b0bd84cb9e7 286 Gene3D G3DSA:3.30.1330.10 1 133 5.0E-26 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0436 acee0be7beaa150309500b0bd84cb9e7 286 SUPERFAMILY SSF56042 135 274 2.44E-24 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0436 acee0be7beaa150309500b0bd84cb9e7 286 Gene3D G3DSA:3.90.650.10 136 284 4.2E-34 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0436 acee0be7beaa150309500b0bd84cb9e7 286 PIRSF PIRSF005303 1 285 5.4E-63 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 Mlab_0436 acee0be7beaa150309500b0bd84cb9e7 286 Pfam PF00586 AIR synthase related protein, N-terminal domain 21 129 3.5E-16 T 23-10-2018 IPR016188 PurM-like, N-terminal domain Mlab_0436 acee0be7beaa150309500b0bd84cb9e7 286 SUPERFAMILY SSF55326 5 130 1.5E-23 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0436 acee0be7beaa150309500b0bd84cb9e7 286 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 18 284 7.0E-62 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 Mlab_0436 acee0be7beaa150309500b0bd84cb9e7 286 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 285 23.633 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 Mlab_0099 271d72c014b598f868203490adb7e052 150 Gene3D G3DSA:1.10.1200.60 90 146 2.7E-19 T 23-10-2018 IPR015974 Ribosomal protein L19/L19e, domain 3 GO:0003735|GO:0006412 Mlab_0099 271d72c014b598f868203490adb7e052 150 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 3 149 25.344 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0099 271d72c014b598f868203490adb7e052 150 Gene3D G3DSA:1.10.1650.10 1 56 1.1E-24 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0099 271d72c014b598f868203490adb7e052 150 SUPERFAMILY SSF48140 3 142 2.88E-49 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0099 271d72c014b598f868203490adb7e052 150 Pfam PF01280 Ribosomal protein L19e 4 143 1.4E-54 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0099 271d72c014b598f868203490adb7e052 150 ProSitePatterns PS00526 Ribosomal protein L19e signature. 7 26 - T 23-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0099 271d72c014b598f868203490adb7e052 150 SMART SM01416 3 146 5.4E-82 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0099 271d72c014b598f868203490adb7e052 150 Gene3D G3DSA:1.20.5.560 57 89 7.9E-6 T 23-10-2018 IPR015973 Ribosomal protein L19/L19e, domain 2 GO:0003735|GO:0006412 Mlab_1271 a15e92da0027341273bf86fde3a10b8e 319 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 23-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 Mlab_1271 a15e92da0027341273bf86fde3a10b8e 319 PIRSF PIRSF000102 1 316 2.8E-92 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Mlab_1271 a15e92da0027341273bf86fde3a10b8e 319 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 3 145 9.4E-32 T 23-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 Mlab_1271 a15e92da0027341273bf86fde3a10b8e 319 SUPERFAMILY SSF51735 3 145 8.72E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1271 a15e92da0027341273bf86fde3a10b8e 319 Gene3D G3DSA:3.90.110.10 148 309 1.3E-46 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Mlab_1271 a15e92da0027341273bf86fde3a10b8e 319 SUPERFAMILY SSF56327 147 309 2.51E-45 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Mlab_1271 a15e92da0027341273bf86fde3a10b8e 319 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 310 3.6E-23 T 23-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 Mlab_1271 a15e92da0027341273bf86fde3a10b8e 319 Gene3D G3DSA:3.40.50.720 1 146 1.3E-38 T 23-10-2018 Mlab_1271 a15e92da0027341273bf86fde3a10b8e 319 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 2.4E-16 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Mlab_1271 a15e92da0027341273bf86fde3a10b8e 319 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 2.4E-16 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Mlab_1271 a15e92da0027341273bf86fde3a10b8e 319 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 2.4E-16 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Mlab_1549 04f1f4d2131b037b0977c6d9c5cf0d78 124 SUPERFAMILY SSF46785 6 93 4.16E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1549 04f1f4d2131b037b0977c6d9c5cf0d78 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.1E-14 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Mlab_1549 04f1f4d2131b037b0977c6d9c5cf0d78 124 Gene3D G3DSA:1.10.10.10 10 124 6.0E-29 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1549 04f1f4d2131b037b0977c6d9c5cf0d78 124 SMART SM00345 17 76 1.1E-12 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Mlab_0720 ca42af3f06be54af6796ef60e4109bdc 234 Pfam PF13847 Methyltransferase domain 44 162 1.3E-22 T 23-10-2018 IPR025714 Methyltransferase domain Mlab_0720 ca42af3f06be54af6796ef60e4109bdc 234 SUPERFAMILY SSF53335 3 215 6.87E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0720 ca42af3f06be54af6796ef60e4109bdc 234 Gene3D G3DSA:3.40.50.150 4 223 5.1E-37 T 23-10-2018 Mlab_0635 68d41f2f479cd06ced12a0a90523c674 424 SUPERFAMILY SSF50249 160 251 1.91E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0635 68d41f2f479cd06ced12a0a90523c674 424 Gene3D G3DSA:2.40.50.140 45 149 3.8E-14 T 23-10-2018 Mlab_0635 68d41f2f479cd06ced12a0a90523c674 424 SUPERFAMILY SSF50249 48 126 2.29E-12 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0635 68d41f2f479cd06ced12a0a90523c674 424 Gene3D G3DSA:2.40.50.140 152 254 2.3E-9 T 23-10-2018 Mlab_0635 68d41f2f479cd06ced12a0a90523c674 424 SUPERFAMILY SSF50249 254 347 1.71E-12 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0635 68d41f2f479cd06ced12a0a90523c674 424 Gene3D G3DSA:2.40.50.140 255 349 1.4E-18 T 23-10-2018 Mlab_0075 2ec66f08f9cd48dc4c5e05b5832aff17 143 SUPERFAMILY SSF51283 1 142 9.16E-43 T 23-10-2018 IPR036157 dUTPase-like superfamily Mlab_0075 2ec66f08f9cd48dc4c5e05b5832aff17 143 Gene3D G3DSA:2.70.40.10 40 143 1.3E-31 T 23-10-2018 IPR036157 dUTPase-like superfamily Mlab_0075 2ec66f08f9cd48dc4c5e05b5832aff17 143 Gene3D G3DSA:2.70.40.10 1 39 8.2E-8 T 23-10-2018 IPR036157 dUTPase-like superfamily Mlab_0075 2ec66f08f9cd48dc4c5e05b5832aff17 143 Pfam PF00692 dUTPase 30 137 1.9E-19 T 23-10-2018 IPR029054 dUTPase-like Mlab_0075 2ec66f08f9cd48dc4c5e05b5832aff17 143 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 38 143 1.5E-31 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 SUPERFAMILY SSF50677 200 334 1.05E-43 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 TIGRFAM TIGR00422 valS: valine--tRNA ligase 7 807 2.7E-268 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 Gene3D G3DSA:3.90.740.10 175 336 6.0E-237 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 Gene3D G3DSA:3.40.50.620 26 523 6.0E-237 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 Gene3D G3DSA:1.10.730.10 6 733 6.0E-237 T 23-10-2018 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 Hamap MF_02005 Valine--tRNA ligase [valS]. 6 773 27.377 T 23-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 560 5.6E-132 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 Pfam PF08264 Anticodon-binding domain of tRNA 604 744 9.1E-31 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 PRINTS PR00986 Valyl-tRNA synthetase signature 39 50 1.0E-20 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 PRINTS PR00986 Valyl-tRNA synthetase signature 474 492 1.0E-20 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 PRINTS PR00986 Valyl-tRNA synthetase signature 224 241 1.0E-20 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 PRINTS PR00986 Valyl-tRNA synthetase signature 339 352 1.0E-20 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 PRINTS PR00986 Valyl-tRNA synthetase signature 445 466 1.0E-20 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 SUPERFAMILY SSF47323 575 756 6.35E-41 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 SUPERFAMILY SSF52374 3 572 1.78E-133 T 23-10-2018 Mlab_0403 90c03ab04d8f420e926cc74587d48434 865 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 57 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0849 c14d28928da7f477d97f62c541f9eec1 237 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 6 201 4.7E-42 T 23-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 Mlab_0849 c14d28928da7f477d97f62c541f9eec1 237 Gene3D G3DSA:3.30.70.2660 2 223 2.6E-88 T 23-10-2018 Mlab_0849 c14d28928da7f477d97f62c541f9eec1 237 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 7 50 1.3E-10 T 23-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal Mlab_0849 c14d28928da7f477d97f62c541f9eec1 237 TIGRFAM TIGR01876 cas_Cas5d: CRISPR-associated protein Cas5, subtype I-C/DVULG 9 207 1.4E-71 T 23-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 Mlab_0849 c14d28928da7f477d97f62c541f9eec1 237 PIRSF PIRSF029950 2 220 3.9E-64 T 23-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 Mlab_1357 9845c5834f1b97901681decf4a857b6e 267 Pfam PF00809 Pterin binding enzyme 19 250 2.7E-45 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Mlab_1357 9845c5834f1b97901681decf4a857b6e 267 SUPERFAMILY SSF51717 7 266 1.7E-63 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Mlab_1357 9845c5834f1b97901681decf4a857b6e 267 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 18 264 1.1E-54 T 23-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 Mlab_1357 9845c5834f1b97901681decf4a857b6e 267 Gene3D G3DSA:3.20.20.20 7 267 9.9E-68 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Mlab_0038 a76c04167f41a162f77991fa7bb1ac77 94 Pfam PF07876 Stress responsive A/B Barrel Domain 2 93 1.3E-18 T 23-10-2018 IPR013097 Stress responsive alpha-beta barrel Mlab_0038 a76c04167f41a162f77991fa7bb1ac77 94 SUPERFAMILY SSF54909 1 93 1.18E-22 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel Mlab_0038 a76c04167f41a162f77991fa7bb1ac77 94 SMART SM00886 2 94 8.2E-26 T 23-10-2018 IPR013097 Stress responsive alpha-beta barrel Mlab_0038 a76c04167f41a162f77991fa7bb1ac77 94 Gene3D G3DSA:3.30.70.100 1 94 1.0E-18 T 23-10-2018 Mlab_1639 35ea3e7425e1cc9a58b9d234c7cc18cf 330 Gene3D G3DSA:3.40.50.720 4 316 2.5E-110 T 23-10-2018 Mlab_1639 35ea3e7425e1cc9a58b9d234c7cc18cf 330 SUPERFAMILY SSF51735 2 158 6.37E-43 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1639 35ea3e7425e1cc9a58b9d234c7cc18cf 330 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 330 9.2E-115 T 23-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Mlab_1639 35ea3e7425e1cc9a58b9d234c7cc18cf 330 Gene3D G3DSA:3.30.360.10 141 302 2.5E-110 T 23-10-2018 Mlab_1639 35ea3e7425e1cc9a58b9d234c7cc18cf 330 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 135 5.9E-29 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Mlab_1639 35ea3e7425e1cc9a58b9d234c7cc18cf 330 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 324 40.025 T 23-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Mlab_1639 35ea3e7425e1cc9a58b9d234c7cc18cf 330 SMART SM00859 2 135 4.9E-41 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Mlab_1639 35ea3e7425e1cc9a58b9d234c7cc18cf 330 SUPERFAMILY SSF55347 143 298 2.94E-44 T 23-10-2018 Mlab_1639 35ea3e7425e1cc9a58b9d234c7cc18cf 330 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 138 154 - T 23-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Mlab_1639 35ea3e7425e1cc9a58b9d234c7cc18cf 330 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 160 301 1.0E-16 T 23-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Mlab_0297 e869783b3ec9946b7b516b2838c78607 373 Pfam PF07690 Major Facilitator Superfamily 3 251 5.6E-23 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_0297 e869783b3ec9946b7b516b2838c78607 373 SUPERFAMILY SSF103473 4 367 1.01E-48 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_0297 e869783b3ec9946b7b516b2838c78607 373 Gene3D G3DSA:1.20.1250.20 1 361 3.2E-43 T 23-10-2018 Mlab_1062 2b4e9527df694d2a2e7683a54b82bfdb 298 SUPERFAMILY SSF53850 38 297 1.2E-82 T 23-10-2018 Mlab_1062 2b4e9527df694d2a2e7683a54b82bfdb 298 Gene3D G3DSA:3.40.190.100 123 229 2.1E-100 T 23-10-2018 Mlab_1062 2b4e9527df694d2a2e7683a54b82bfdb 298 Gene3D G3DSA:3.40.190.10 42 293 2.1E-100 T 23-10-2018 Mlab_1062 2b4e9527df694d2a2e7683a54b82bfdb 298 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 40 283 1.2E-68 T 23-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 Mlab_1672 4381a50bde035c312bd7c46edb5b1472 307 Pfam PF01955 Adenosylcobinamide amidohydrolase 19 175 5.1E-25 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ Mlab_1672 4381a50bde035c312bd7c46edb5b1472 307 Pfam PF04071 Cysteine-rich small domain 222 301 9.0E-30 T 23-10-2018 IPR007212 Cysteine-rich small domain Mlab_1489 aff7c5be7a4e4b07b104c48ca3512ba1 218 SUPERFAMILY SSF51735 1 134 1.16E-32 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1489 aff7c5be7a4e4b07b104c48ca3512ba1 218 SUPERFAMILY SSF116726 143 210 1.01E-11 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Mlab_1489 aff7c5be7a4e4b07b104c48ca3512ba1 218 Pfam PF02254 TrkA-N domain 4 113 1.9E-27 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Mlab_1489 aff7c5be7a4e4b07b104c48ca3512ba1 218 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.8E-10 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Mlab_1489 aff7c5be7a4e4b07b104c48ca3512ba1 218 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.8E-10 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Mlab_1489 aff7c5be7a4e4b07b104c48ca3512ba1 218 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.8E-10 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Mlab_1489 aff7c5be7a4e4b07b104c48ca3512ba1 218 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 1.8E-10 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Mlab_1489 aff7c5be7a4e4b07b104c48ca3512ba1 218 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.8E-10 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Mlab_1489 aff7c5be7a4e4b07b104c48ca3512ba1 218 Pfam PF02080 TrkA-C domain 146 205 4.4E-12 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Mlab_1489 aff7c5be7a4e4b07b104c48ca3512ba1 218 Gene3D G3DSA:3.30.70.1450 125 210 1.7E-14 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Mlab_1489 aff7c5be7a4e4b07b104c48ca3512ba1 218 Gene3D G3DSA:3.40.50.720 1 124 2.4E-35 T 23-10-2018 Mlab_1523 33f749b86dbd2303a893e0a78e0c84bd 526 Pfam PF03063 Prismane/CO dehydrogenase family 1 520 2.2E-143 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1523 33f749b86dbd2303a893e0a78e0c84bd 526 Gene3D G3DSA:3.40.50.2030 356 524 1.4E-57 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1523 33f749b86dbd2303a893e0a78e0c84bd 526 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 525 19.745 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1523 33f749b86dbd2303a893e0a78e0c84bd 526 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 522 9.3E-189 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1523 33f749b86dbd2303a893e0a78e0c84bd 526 Gene3D G3DSA:1.20.1270.20 124 205 3.2E-21 T 23-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1523 33f749b86dbd2303a893e0a78e0c84bd 526 Gene3D G3DSA:1.20.1270.20 1 121 9.3E-21 T 23-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1523 33f749b86dbd2303a893e0a78e0c84bd 526 PIRSF PIRSF000076 1 525 1.6E-206 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_1523 33f749b86dbd2303a893e0a78e0c84bd 526 SUPERFAMILY SSF56821 1 523 8.85E-166 T 23-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 Mlab_1523 33f749b86dbd2303a893e0a78e0c84bd 526 Gene3D G3DSA:3.40.50.2030 207 355 1.6E-59 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Mlab_0370 1214bc443226ec02b098831ef91f7098 154 Gene3D G3DSA:3.90.1140.10 1 154 1.4E-37 T 23-10-2018 Mlab_0370 1214bc443226ec02b098831ef91f7098 154 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 12 154 2.8E-35 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 Mlab_0370 1214bc443226ec02b098831ef91f7098 154 SUPERFAMILY SSF55144 11 154 1.55E-32 T 23-10-2018 IPR009097 Cyclic phosphodiesterase Mlab_0370 1214bc443226ec02b098831ef91f7098 154 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 3 154 16.843 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 Mlab_0370 1214bc443226ec02b098831ef91f7098 154 Pfam PF02834 LigT like Phosphoesterase 14 61 4.3E-10 T 23-10-2018 IPR014051 Phosphoesterase, HXTX Mlab_0370 1214bc443226ec02b098831ef91f7098 154 Pfam PF02834 LigT like Phosphoesterase 75 146 3.2E-10 T 23-10-2018 IPR014051 Phosphoesterase, HXTX Mlab_0767 6e7714635b3e59084f054b3b2d97093d 199 Gene3D G3DSA:3.40.50.620 2 177 5.1E-34 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0767 6e7714635b3e59084f054b3b2d97093d 199 SUPERFAMILY SSF52374 3 163 4.69E-22 T 23-10-2018 Mlab_0767 6e7714635b3e59084f054b3b2d97093d 199 Pfam PF01467 Cytidylyltransferase-like 5 59 2.3E-12 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Mlab_0767 6e7714635b3e59084f054b3b2d97093d 199 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 62 4.2E-14 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Mlab_0767 6e7714635b3e59084f054b3b2d97093d 199 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 199 75.273 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 Mlab_0767 6e7714635b3e59084f054b3b2d97093d 199 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 3 166 3.6E-57 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 Mlab_0546 c28721cbdb49239ee78e5105baaecef2 158 Gene3D G3DSA:3.50.80.10 1 136 3.5E-40 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily Mlab_0546 c28721cbdb49239ee78e5105baaecef2 158 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 135 2.6E-44 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 Mlab_0546 c28721cbdb49239ee78e5105baaecef2 158 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 136 9.0E-30 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 SUPERFAMILY SSF52540 476 800 1.54E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 Gene3D G3DSA:1.10.8.60 720 813 2.4E-14 T 23-10-2018 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 216 345 1.4E-50 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 517 647 1.3E-45 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 Gene3D G3DSA:2.40.40.20 1 89 6.0E-28 T 23-10-2018 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 4 690 3.7E-257 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 SUPERFAMILY SSF50692 3 88 4.72E-26 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 Gene3D G3DSA:1.10.8.60 380 470 6.5E-16 T 23-10-2018 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 ProSitePatterns PS00674 AAA-protein family signature. 316 334 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 ProSitePatterns PS00674 AAA-protein family signature. 618 636 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 5 88 1.1E-27 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 SUPERFAMILY SSF52540 175 458 1.48E-66 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 SMART SM01073 5 89 1.8E-35 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 Gene3D G3DSA:3.40.50.300 175 346 2.6E-76 T 23-10-2018 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 Gene3D G3DSA:3.40.50.300 476 648 8.7E-79 T 23-10-2018 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 SMART SM00382 212 348 1.6E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 SMART SM00382 513 650 2.9E-22 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 Gene3D G3DSA:1.10.8.60 649 692 8.7E-79 T 23-10-2018 Mlab_0625 585336f1738a8226c3d716d4d52c80b2 826 Gene3D G3DSA:1.10.8.60 347 375 2.6E-76 T 23-10-2018 Mlab_0169 f408b3f3e477dfe3be4bef4956bbe720 518 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 431 1.1E-63 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain Mlab_0169 f408b3f3e477dfe3be4bef4956bbe720 518 Gene3D G3DSA:3.10.105.10 268 480 1.7E-117 T 23-10-2018 Mlab_0169 f408b3f3e477dfe3be4bef4956bbe720 518 PIRSF PIRSF002741 10 512 4.1E-88 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Mlab_0169 f408b3f3e477dfe3be4bef4956bbe720 518 Gene3D G3DSA:3.40.190.10 45 486 1.7E-117 T 23-10-2018 Mlab_0169 f408b3f3e477dfe3be4bef4956bbe720 518 Gene3D G3DSA:3.90.76.10 60 175 1.7E-117 T 23-10-2018 Mlab_0169 f408b3f3e477dfe3be4bef4956bbe720 518 SUPERFAMILY SSF53850 46 509 1.17E-99 T 23-10-2018 Mlab_0574 23b5f8b302cfae9e77b7bc2fe2f0e0ec 566 TIGRFAM TIGR03121 one_C_dehyd_A: formylmethanofuran dehydrogenase subunit A 3 552 2.6E-224 T 23-10-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A Mlab_0574 23b5f8b302cfae9e77b7bc2fe2f0e0ec 566 PIRSF PIRSF006453 1 565 2.7E-222 T 23-10-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A Mlab_0574 23b5f8b302cfae9e77b7bc2fe2f0e0ec 566 Gene3D G3DSA:2.30.40.10 1 73 1.3E-10 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_0574 23b5f8b302cfae9e77b7bc2fe2f0e0ec 566 Pfam PF07969 Amidohydrolase family 40 496 6.0E-73 T 23-10-2018 IPR013108 Amidohydrolase 3 Mlab_0574 23b5f8b302cfae9e77b7bc2fe2f0e0ec 566 SUPERFAMILY SSF51556 52 450 1.97E-10 T 23-10-2018 IPR032466 Metal-dependent hydrolase Mlab_0574 23b5f8b302cfae9e77b7bc2fe2f0e0ec 566 SUPERFAMILY SSF51338 421 517 2.75E-16 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_0574 23b5f8b302cfae9e77b7bc2fe2f0e0ec 566 SUPERFAMILY SSF51338 1 70 1.79E-15 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_0376 2dc1e41d699126e4273f3ee98422a13c 412 SUPERFAMILY SSF53850 37 139 3.48E-10 T 23-10-2018 Mlab_0376 2dc1e41d699126e4273f3ee98422a13c 412 Pfam PF13379 NMT1-like family 237 405 8.1E-9 T 23-10-2018 Mlab_0376 2dc1e41d699126e4273f3ee98422a13c 412 Pfam PF13379 NMT1-like family 39 139 7.9E-11 T 23-10-2018 Mlab_0376 2dc1e41d699126e4273f3ee98422a13c 412 Gene3D G3DSA:3.40.190.10 24 206 2.2E-16 T 23-10-2018 Mlab_0376 2dc1e41d699126e4273f3ee98422a13c 412 Gene3D G3DSA:3.40.190.10 238 375 8.0E-11 T 23-10-2018 Mlab_0376 2dc1e41d699126e4273f3ee98422a13c 412 SUPERFAMILY SSF53850 240 405 8.15E-10 T 23-10-2018 Mlab_1592 c4d504cb01ae463dd90a4eb7b3a6c13c 499 Pfam PF13091 PLD-like domain 340 462 4.4E-23 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Mlab_1592 c4d504cb01ae463dd90a4eb7b3a6c13c 499 Pfam PF13091 PLD-like domain 146 286 4.3E-13 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Mlab_1592 c4d504cb01ae463dd90a4eb7b3a6c13c 499 Gene3D G3DSA:3.30.870.10 121 310 2.4E-46 T 23-10-2018 Mlab_1592 c4d504cb01ae463dd90a4eb7b3a6c13c 499 Pfam PF13396 Phospholipase_D-nuclease N-terminal 28 68 2.4E-11 T 23-10-2018 IPR027379 Cardiolipin synthase N-terminal Mlab_1592 c4d504cb01ae463dd90a4eb7b3a6c13c 499 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 18 499 5.5E-155 T 23-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 Mlab_1592 c4d504cb01ae463dd90a4eb7b3a6c13c 499 SUPERFAMILY SSF56024 117 328 1.92E-51 T 23-10-2018 Mlab_1592 c4d504cb01ae463dd90a4eb7b3a6c13c 499 Hamap MF_01916 Cardiolipin synthase. 20 499 43.535 T 23-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 Mlab_1592 c4d504cb01ae463dd90a4eb7b3a6c13c 499 SUPERFAMILY SSF56024 279 485 1.05E-45 T 23-10-2018 Mlab_1592 c4d504cb01ae463dd90a4eb7b3a6c13c 499 Gene3D G3DSA:3.30.870.10 321 467 1.6E-24 T 23-10-2018 Mlab_1592 c4d504cb01ae463dd90a4eb7b3a6c13c 499 SMART SM00155 411 438 4.8 T 23-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 Mlab_1592 c4d504cb01ae463dd90a4eb7b3a6c13c 499 SMART SM00155 228 255 5.2E-6 T 23-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 Mlab_0496 31c7339c48ff4eb021d563a879d410f7 331 SUPERFAMILY SSF55326 37 158 4.19E-28 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0496 31c7339c48ff4eb021d563a879d410f7 331 Pfam PF02769 AIR synthase related protein, C-terminal domain 188 308 2.3E-16 T 23-10-2018 IPR010918 PurM-like, C-terminal domain Mlab_0496 31c7339c48ff4eb021d563a879d410f7 331 PIRSF PIRSF036540 8 331 2.4E-119 T 23-10-2018 IPR011413 Uncharacterised conserved protein UCP036540 Mlab_0496 31c7339c48ff4eb021d563a879d410f7 331 Pfam PF00586 AIR synthase related protein, N-terminal domain 48 151 4.4E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain Mlab_0496 31c7339c48ff4eb021d563a879d410f7 331 SUPERFAMILY SSF56042 163 313 1.09E-22 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0496 31c7339c48ff4eb021d563a879d410f7 331 TIGRFAM TIGR03267 methan_mark_2: putative methanogenesis marker protein 2 11 327 3.9E-117 T 23-10-2018 IPR017668 Putative methanogenesis marker protein 2 Mlab_0496 31c7339c48ff4eb021d563a879d410f7 331 Gene3D G3DSA:3.30.1330.10 17 154 1.4E-24 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0496 31c7339c48ff4eb021d563a879d410f7 331 Gene3D G3DSA:3.90.650.10 155 320 5.3E-20 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0815 985e2098f90699933095581f8b40ad85 78 Pfam PF13192 Thioredoxin domain 3 76 7.1E-26 T 23-10-2018 IPR012336 Thioredoxin-like fold Mlab_0815 985e2098f90699933095581f8b40ad85 78 SUPERFAMILY SSF52833 1 76 6.32E-18 T 23-10-2018 IPR036249 Thioredoxin-like superfamily Mlab_0815 985e2098f90699933095581f8b40ad85 78 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 1 77 1.6E-25 T 23-10-2018 IPR005243 Redox-active disulphide protein 2 Mlab_0815 985e2098f90699933095581f8b40ad85 78 Gene3D G3DSA:3.40.30.10 1 77 7.7E-28 T 23-10-2018 Mlab_0815 985e2098f90699933095581f8b40ad85 78 PIRSF PIRSF037031 1 78 2.6E-30 T 23-10-2018 IPR005243 Redox-active disulphide protein 2 Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 Gene3D G3DSA:1.10.287.110 2 115 7.2E-36 T 23-10-2018 IPR036869 Chaperone J-domain superfamily Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 SUPERFAMILY SSF49493 112 269 4.45E-18 T 23-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 Gene3D G3DSA:2.10.230.10 146 209 1.8E-34 T 23-10-2018 Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 SUPERFAMILY SSF57938 144 211 4.45E-16 T 23-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 Pfam PF01556 DnaJ C terminal domain 121 334 2.4E-33 T 23-10-2018 IPR002939 Chaperone DnaJ, C-terminal Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 SMART SM00271 4 61 7.1E-32 T 23-10-2018 IPR001623 DnaJ domain Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 PRINTS PR00625 DnaJ domain signature 25 40 1.2E-26 T 23-10-2018 IPR001623 DnaJ domain Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 PRINTS PR00625 DnaJ domain signature 41 61 1.2E-26 T 23-10-2018 IPR001623 DnaJ domain Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 PRINTS PR00625 DnaJ domain signature 7 25 1.2E-26 T 23-10-2018 IPR001623 DnaJ domain Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 PRINTS PR00625 DnaJ domain signature 61 80 1.2E-26 T 23-10-2018 IPR001623 DnaJ domain Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 351 9.0E-125 T 23-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 SUPERFAMILY SSF46565 2 106 1.7E-33 T 23-10-2018 IPR036869 Chaperone J-domain superfamily Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 Pfam PF00684 DnaJ central domain 146 209 1.4E-13 T 23-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 373 35.488 T 23-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 SUPERFAMILY SSF49493 261 345 4.45E-19 T 23-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 23-10-2018 IPR018253 DnaJ domain, conserved site Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 Pfam PF00226 DnaJ domain 6 66 8.0E-28 T 23-10-2018 IPR001623 DnaJ domain Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 Gene3D G3DSA:2.60.260.20 116 251 1.8E-34 T 23-10-2018 Mlab_0942 20c621c74db1728361b1b070e7222bb1 377 Gene3D G3DSA:2.60.260.20 256 367 3.7E-24 T 23-10-2018 Mlab_0054 717da692d7661adcea31adc84644a9cc 319 Gene3D G3DSA:3.30.930.10 71 270 7.5E-49 T 23-10-2018 Mlab_0054 717da692d7661adcea31adc84644a9cc 319 SUPERFAMILY SSF50037 273 318 1.79E-6 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal Mlab_0054 717da692d7661adcea31adc84644a9cc 319 SUPERFAMILY SSF55681 73 264 1.04E-47 T 23-10-2018 Mlab_0054 717da692d7661adcea31adc84644a9cc 319 Pfam PF08279 HTH domain 7 57 4.2E-14 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 Mlab_0054 717da692d7661adcea31adc84644a9cc 319 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 6 318 31.066 T 23-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 Mlab_0054 717da692d7661adcea31adc84644a9cc 319 Gene3D G3DSA:2.30.30.100 273 319 2.0E-10 T 23-10-2018 Mlab_0054 717da692d7661adcea31adc84644a9cc 319 Gene3D G3DSA:1.10.10.10 1 62 9.8E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0054 717da692d7661adcea31adc84644a9cc 319 Pfam PF03099 Biotin/lipoate A/B protein ligase family 89 213 5.8E-13 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Mlab_0054 717da692d7661adcea31adc84644a9cc 319 Pfam PF02237 Biotin protein ligase C terminal domain 279 318 1.0E-6 T 23-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Mlab_0054 717da692d7661adcea31adc84644a9cc 319 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 83 317 4.9E-42 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Mlab_0054 717da692d7661adcea31adc84644a9cc 319 SUPERFAMILY SSF46785 11 59 2.17E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0072 db8aba89b350ec86cede8d99956b9d6a 282 SMART SM00359 203 276 0.0068 T 23-10-2018 IPR002478 PUA domain GO:0003723 Mlab_0072 db8aba89b350ec86cede8d99956b9d6a 282 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 137 1.6E-21 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 Mlab_0072 db8aba89b350ec86cede8d99956b9d6a 282 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 138 198 6.3E-18 T 23-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 Mlab_0072 db8aba89b350ec86cede8d99956b9d6a 282 SUPERFAMILY SSF55120 3 198 5.12E-60 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Mlab_0072 db8aba89b350ec86cede8d99956b9d6a 282 SMART SM01136 3 21 0.0019 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 Mlab_0072 db8aba89b350ec86cede8d99956b9d6a 282 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 4 277 9.3E-89 T 23-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 Mlab_0072 db8aba89b350ec86cede8d99956b9d6a 282 Gene3D G3DSA:2.30.130.70 196 278 4.2E-95 T 23-10-2018 Mlab_0072 db8aba89b350ec86cede8d99956b9d6a 282 Pfam PF01472 PUA domain 203 261 2.2E-9 T 23-10-2018 IPR002478 PUA domain GO:0003723 Mlab_0072 db8aba89b350ec86cede8d99956b9d6a 282 SUPERFAMILY SSF88697 203 266 2.32E-10 T 23-10-2018 IPR015947 PUA-like superfamily Mlab_0072 db8aba89b350ec86cede8d99956b9d6a 282 Gene3D G3DSA:3.30.2350.10 4 195 4.2E-95 T 23-10-2018 Mlab_1583 f02e7e6ea6b1caa1cbc15778fab00d77 158 SMART SM00739 99 126 0.0043 T 23-10-2018 IPR005824 KOW Mlab_1583 f02e7e6ea6b1caa1cbc15778fab00d77 158 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 11 158 6.5E-44 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 Mlab_1583 f02e7e6ea6b1caa1cbc15778fab00d77 158 SUPERFAMILY SSF50104 59 155 9.46E-16 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily Mlab_1583 f02e7e6ea6b1caa1cbc15778fab00d77 158 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 9 155 34.805 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 Mlab_1583 f02e7e6ea6b1caa1cbc15778fab00d77 158 SUPERFAMILY SSF82679 8 58 1.02E-5 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Mlab_1583 f02e7e6ea6b1caa1cbc15778fab00d77 158 Gene3D G3DSA:3.30.70.940 6 94 5.6E-21 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Mlab_1583 f02e7e6ea6b1caa1cbc15778fab00d77 158 Pfam PF00467 KOW motif 103 133 1.5E-5 T 23-10-2018 IPR005824 KOW Mlab_1583 f02e7e6ea6b1caa1cbc15778fab00d77 158 SMART SM00738 7 94 5.8E-9 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Mlab_1583 f02e7e6ea6b1caa1cbc15778fab00d77 158 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 10 91 3.2E-18 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Mlab_1583 f02e7e6ea6b1caa1cbc15778fab00d77 158 Gene3D G3DSA:2.30.30.30 95 158 6.5E-27 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 Mlab_1521 424ad9366596c7c1499a208553ea66f4 163 PIRSF PIRSF005859 2 163 8.7E-43 T 23-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 Mlab_1521 424ad9366596c7c1499a208553ea66f4 163 Gene3D G3DSA:1.20.1260.100 7 163 9.6E-44 T 23-10-2018 IPR038330 TspO/MBR-related superfamily Mlab_1521 424ad9366596c7c1499a208553ea66f4 163 Pfam PF03073 TspO/MBR family 16 161 1.5E-38 T 23-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 Mlab_1131 fbd51ff3391ba35e4bc4f7b013d63534 179 SUPERFAMILY SSF52218 1 178 2.02E-41 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1131 fbd51ff3391ba35e4bc4f7b013d63534 179 Pfam PF03358 NADPH-dependent FMN reductase 3 122 2.4E-27 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Mlab_1131 fbd51ff3391ba35e4bc4f7b013d63534 179 Gene3D G3DSA:3.40.50.360 2 178 1.7E-46 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0570 4d6fee29995696e2a9c450c934eef9d1 119 SUPERFAMILY SSF101332 24 101 1.29E-6 T 23-10-2018 IPR036606 EhaM-like superfamily Mlab_0570 4d6fee29995696e2a9c450c934eef9d1 119 Pfam PF09218 Domain of unknown function (DUF1959) 23 98 2.0E-8 T 23-10-2018 IPR012056 [NiFe]-hydrogenase-3-type complex Eha, subunit EhaM Mlab_0570 4d6fee29995696e2a9c450c934eef9d1 119 Gene3D G3DSA:1.10.3070.10 6 116 7.4E-9 T 23-10-2018 IPR036606 EhaM-like superfamily Mlab_1188 a14a85d16fe90ce09338781011500a15 682 SUPERFAMILY SSF51735 410 550 2.32E-30 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1188 a14a85d16fe90ce09338781011500a15 682 Pfam PF02080 TrkA-C domain 606 673 1.6E-14 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Mlab_1188 a14a85d16fe90ce09338781011500a15 682 Gene3D G3DSA:3.40.50.720 410 568 1.2E-33 T 23-10-2018 Mlab_1188 a14a85d16fe90ce09338781011500a15 682 Gene3D G3DSA:3.30.70.1450 604 679 5.4E-16 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Mlab_1188 a14a85d16fe90ce09338781011500a15 682 SUPERFAMILY SSF116726 597 673 2.62E-13 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Mlab_1188 a14a85d16fe90ce09338781011500a15 682 Pfam PF02254 TrkA-N domain 412 526 5.0E-21 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Mlab_1188 a14a85d16fe90ce09338781011500a15 682 Pfam PF00999 Sodium/hydrogen exchanger family 11 376 4.1E-61 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Mlab_1188 a14a85d16fe90ce09338781011500a15 682 Gene3D G3DSA:1.20.1530.20 4 384 2.3E-81 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily Mlab_0390 ab973f40187f94ed23b6f2247c6d358e 526 Gene3D G3DSA:1.20.1720.10 13 225 3.5E-29 T 23-10-2018 Mlab_0390 ab973f40187f94ed23b6f2247c6d358e 526 Pfam PF07690 Major Facilitator Superfamily 27 382 2.0E-39 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_0390 ab973f40187f94ed23b6f2247c6d358e 526 Gene3D G3DSA:1.20.1250.20 255 384 6.1E-7 T 23-10-2018 Mlab_0390 ab973f40187f94ed23b6f2247c6d358e 526 SUPERFAMILY SSF103473 368 513 2.62E-9 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_0390 ab973f40187f94ed23b6f2247c6d358e 526 SUPERFAMILY SSF103473 5 379 4.05E-42 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_0390 ab973f40187f94ed23b6f2247c6d358e 526 Gene3D G3DSA:1.20.1250.20 385 520 2.0E-7 T 23-10-2018 Mlab_1289 4c46ca71d8f2a39d1b8cbb30f3335e6f 259 Gene3D G3DSA:3.40.50.300 2 255 1.9E-67 T 23-10-2018 Mlab_1289 4c46ca71d8f2a39d1b8cbb30f3335e6f 259 Pfam PF00005 ABC transporter 22 170 6.2E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1289 4c46ca71d8f2a39d1b8cbb30f3335e6f 259 SUPERFAMILY SSF52540 5 227 8.61E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1289 4c46ca71d8f2a39d1b8cbb30f3335e6f 259 SMART SM00382 30 214 9.4E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1289 4c46ca71d8f2a39d1b8cbb30f3335e6f 259 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0853 fa2b8c3752b1192ebf05688bc25f11ed 96 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 95 16.271 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Mlab_0853 fa2b8c3752b1192ebf05688bc25f11ed 96 SUPERFAMILY SSF143430 1 88 4.32E-26 T 23-10-2018 Mlab_0853 fa2b8c3752b1192ebf05688bc25f11ed 96 PIRSF PIRSF032582 1 96 4.3E-40 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Mlab_0853 fa2b8c3752b1192ebf05688bc25f11ed 96 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 96 3.8E-20 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Mlab_0853 fa2b8c3752b1192ebf05688bc25f11ed 96 Pfam PF09827 CRISPR associated protein Cas2 1 74 3.8E-23 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 Mlab_0853 fa2b8c3752b1192ebf05688bc25f11ed 96 Gene3D G3DSA:3.30.70.240 1 96 3.6E-33 T 23-10-2018 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Gene3D G3DSA:3.90.199.10 35 489 3.5E-203 T 23-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Gene3D G3DSA:1.10.268.10 373 462 3.5E-203 T 23-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 808 0.0 T 23-10-2018 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 SMART SM00434 14 468 1.5E-260 T 23-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 5 810 23.141 T 23-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Gene3D G3DSA:3.30.1360.40 240 336 3.5E-203 T 23-10-2018 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 35 467 1.1E-154 T 23-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 SUPERFAMILY SSF101904 503 819 4.45E-94 T 23-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Gene3D G3DSA:2.120.10.90 501 809 9.8E-111 T 23-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 509 554 3.1E-12 T 23-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 614 657 1.4E-4 T 23-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 558 599 5.1E-10 T 23-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 762 809 4.2E-13 T 23-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 662 696 1.7E-10 T 23-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 711 758 7.7E-11 T 23-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Mlab_0413 6f2765cf8a033bd5c3e305e0bc466ab5 824 SUPERFAMILY SSF56719 34 490 4.97E-167 T 23-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Mlab_1615 9631812f045eaa12dc5062c84a219277 142 ProSitePatterns PS00055 Ribosomal protein S12 signature. 58 65 - T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1615 9631812f045eaa12dc5062c84a219277 142 Gene3D G3DSA:2.40.50.140 23 142 1.8E-46 T 23-10-2018 Mlab_1615 9631812f045eaa12dc5062c84a219277 142 PIRSF PIRSF002133 14 142 1.3E-30 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1615 9631812f045eaa12dc5062c84a219277 142 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 4 142 6.4E-69 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1615 9631812f045eaa12dc5062c84a219277 142 Pfam PF00164 Ribosomal protein S12/S23 27 140 3.4E-44 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1615 9631812f045eaa12dc5062c84a219277 142 SUPERFAMILY SSF50249 18 140 1.37E-30 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_1615 9631812f045eaa12dc5062c84a219277 142 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 142 40.796 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea Mlab_0500 ff12fb854710164d860dcc59788fe24d 236 PIRSF PIRSF005624 1 193 1.7E-36 T 23-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 Mlab_0500 ff12fb854710164d860dcc59788fe24d 236 SMART SM00382 2 142 2.2E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0500 ff12fb854710164d860dcc59788fe24d 236 Gene3D G3DSA:3.40.50.300 1 188 1.8E-27 T 23-10-2018 Mlab_0500 ff12fb854710164d860dcc59788fe24d 236 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 166 2.6E-13 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain Mlab_0500 ff12fb854710164d860dcc59788fe24d 236 SUPERFAMILY SSF52540 4 193 1.79E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0491 13bb8dbdb82d1fa670c585afade84304 286 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 3 286 34.333 T 23-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 Mlab_0491 13bb8dbdb82d1fa670c585afade84304 286 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 145 166 - T 23-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 Mlab_0491 13bb8dbdb82d1fa670c585afade84304 286 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 187 285 1.5E-30 T 23-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Mlab_0491 13bb8dbdb82d1fa670c585afade84304 286 Pfam PF01634 ATP phosphoribosyltransferase 52 204 1.8E-50 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Mlab_0491 13bb8dbdb82d1fa670c585afade84304 286 Gene3D G3DSA:3.40.190.10 91 180 1.3E-69 T 23-10-2018 Mlab_0491 13bb8dbdb82d1fa670c585afade84304 286 Gene3D G3DSA:3.40.190.10 5 201 1.3E-69 T 23-10-2018 Mlab_0491 13bb8dbdb82d1fa670c585afade84304 286 SUPERFAMILY SSF54913 214 285 8.34E-20 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Mlab_0491 13bb8dbdb82d1fa670c585afade84304 286 Pfam PF08029 HisG, C-terminal domain 211 282 2.8E-25 T 23-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Mlab_0491 13bb8dbdb82d1fa670c585afade84304 286 SUPERFAMILY SSF53850 4 208 3.08E-64 T 23-10-2018 Mlab_0491 13bb8dbdb82d1fa670c585afade84304 286 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 186 2.6E-63 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Mlab_0491 13bb8dbdb82d1fa670c585afade84304 286 Gene3D G3DSA:3.30.70.120 214 286 7.5E-26 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Mlab_1190 55da83a69fb6e7b71045f1137435d1dc 228 Gene3D G3DSA:3.40.50.1000 10 199 1.7E-40 T 23-10-2018 IPR023214 HAD superfamily Mlab_1190 55da83a69fb6e7b71045f1137435d1dc 228 Gene3D G3DSA:1.10.150.520 23 94 1.7E-40 T 23-10-2018 Mlab_1190 55da83a69fb6e7b71045f1137435d1dc 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 4.4E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_1190 55da83a69fb6e7b71045f1137435d1dc 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 4.4E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_1190 55da83a69fb6e7b71045f1137435d1dc 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 4.4E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_1190 55da83a69fb6e7b71045f1137435d1dc 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 9 20 4.4E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_1190 55da83a69fb6e7b71045f1137435d1dc 228 SUPERFAMILY SSF56784 8 226 1.6E-44 T 23-10-2018 IPR036412 HAD-like superfamily Mlab_1190 55da83a69fb6e7b71045f1137435d1dc 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 107 188 1.2E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_1190 55da83a69fb6e7b71045f1137435d1dc 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 192 1.8E-31 T 23-10-2018 Mlab_0978 ed15618e3aa98023cb7fd23b5347e688 338 SUPERFAMILY SSF100950 5 332 5.58E-102 T 23-10-2018 IPR037171 NagB/RpiA transferase-like Mlab_0978 ed15618e3aa98023cb7fd23b5347e688 338 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 3 338 34.761 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Mlab_0978 ed15618e3aa98023cb7fd23b5347e688 338 Gene3D G3DSA:3.40.50.10470 147 336 1.8E-62 T 23-10-2018 Mlab_0978 ed15618e3aa98023cb7fd23b5347e688 338 Pfam PF01008 Initiation factor 2 subunit family 47 330 2.6E-74 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 Mlab_0978 ed15618e3aa98023cb7fd23b5347e688 338 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 34 330 2.1E-110 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Mlab_0978 ed15618e3aa98023cb7fd23b5347e688 338 Gene3D G3DSA:1.20.120.420 1 143 2.5E-35 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Mlab_0978 ed15618e3aa98023cb7fd23b5347e688 338 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 5 329 3.7E-112 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Mlab_1245 81c28186395bbe2f285521ae80fae163 131 ProSitePatterns PS00054 Ribosomal protein S11 signature. 96 118 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site Mlab_1245 81c28186395bbe2f285521ae80fae163 131 Pfam PF00411 Ribosomal protein S11 9 127 7.5E-47 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Mlab_1245 81c28186395bbe2f285521ae80fae163 131 PIRSF PIRSF002131 1 130 2.6E-34 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Mlab_1245 81c28186395bbe2f285521ae80fae163 131 SUPERFAMILY SSF53137 6 129 4.58E-36 T 23-10-2018 Mlab_1245 81c28186395bbe2f285521ae80fae163 131 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 7 128 22.198 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Mlab_1245 81c28186395bbe2f285521ae80fae163 131 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 7 123 4.1E-62 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1245 81c28186395bbe2f285521ae80fae163 131 Gene3D G3DSA:3.30.420.80 1 131 4.4E-61 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 Mlab_0754 6a1317d0ea344076aba9f9110f793826 497 Gene3D G3DSA:3.90.1640.10 168 353 2.9E-29 T 23-10-2018 Mlab_0754 6a1317d0ea344076aba9f9110f793826 497 Gene3D G3DSA:3.40.50.720 15 155 5.6E-28 T 23-10-2018 Mlab_0754 6a1317d0ea344076aba9f9110f793826 497 Pfam PF02254 TrkA-N domain 22 134 1.3E-19 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Mlab_0754 6a1317d0ea344076aba9f9110f793826 497 Pfam PF02272 DHHA1 domain 364 462 4.0E-12 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Mlab_0754 6a1317d0ea344076aba9f9110f793826 497 SUPERFAMILY SSF51735 21 147 1.15E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0754 6a1317d0ea344076aba9f9110f793826 497 SUPERFAMILY SSF64182 169 458 6.41E-52 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily Mlab_0754 6a1317d0ea344076aba9f9110f793826 497 Pfam PF01368 DHH family 171 317 3.7E-12 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Mlab_1418 9888c9341fdcbee9fa3649bf425ff3a3 296 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 42 205 4.8E-22 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Mlab_1418 9888c9341fdcbee9fa3649bf425ff3a3 296 Gene3D G3DSA:3.40.50.970 85 293 1.8E-63 T 23-10-2018 Mlab_1418 9888c9341fdcbee9fa3649bf425ff3a3 296 Gene3D G3DSA:3.40.50.970 7 84 3.4E-17 T 23-10-2018 Mlab_1418 9888c9341fdcbee9fa3649bf425ff3a3 296 SUPERFAMILY SSF52518 9 288 5.54E-76 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_0365 0c6a42d87a4c73569bba33fd66b8e3d6 114 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 109 17.025 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 Mlab_0365 0c6a42d87a4c73569bba33fd66b8e3d6 114 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 108 3.1E-20 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 Mlab_0365 0c6a42d87a4c73569bba33fd66b8e3d6 114 Gene3D G3DSA:3.30.2320.80 1 111 1.5E-19 T 23-10-2018 Mlab_0365 0c6a42d87a4c73569bba33fd66b8e3d6 114 PIRSF PIRSF004761 1 112 1.4E-20 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 Mlab_1283 22291c9bb8f8913fcafa20cdfa2fc450 193 PIRSF PIRSF015877 3 193 1.1E-41 T 23-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing Mlab_0080 2d5813d54ac76f6fdf206dca8f3f13d8 134 Pfam PF14601 DNA_binding protein, TFX, C-term 51 133 1.2E-29 T 23-10-2018 IPR029291 DNA binding protein Tfx, C-terminal Mlab_0080 2d5813d54ac76f6fdf206dca8f3f13d8 134 Gene3D G3DSA:3.30.1190.10 16 133 3.2E-40 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 Mlab_0080 2d5813d54ac76f6fdf206dca8f3f13d8 134 SUPERFAMILY SSF89915 17 132 1.01E-21 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 Mlab_0080 2d5813d54ac76f6fdf206dca8f3f13d8 134 Pfam PF04545 Sigma-70, region 4 6 49 1.3E-8 T 23-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Mlab_0080 2d5813d54ac76f6fdf206dca8f3f13d8 134 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 2 132 8.3E-32 T 23-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 Mlab_0652 93ff844c6c5f6db9c8735a71f045dad5 185 SUPERFAMILY SSF52972 2 177 4.97E-55 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Mlab_0652 93ff844c6c5f6db9c8735a71f045dad5 185 Gene3D G3DSA:3.90.950.10 1 179 1.7E-60 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Mlab_0652 93ff844c6c5f6db9c8735a71f045dad5 185 Pfam PF01725 Ham1 family 2 175 1.2E-50 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 Mlab_0652 93ff844c6c5f6db9c8735a71f045dad5 185 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 178 38.759 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 Mlab_0652 93ff844c6c5f6db9c8735a71f045dad5 185 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 2 176 1.5E-54 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 Mlab_1094 380a4ea9ddc3ec3dd43ff1de4304914b 205 SUPERFAMILY SSF143555 13 173 1.44E-48 T 23-10-2018 Mlab_1094 380a4ea9ddc3ec3dd43ff1de4304914b 205 PIRSF PIRSF006578 1 205 1.5E-88 T 23-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E Mlab_1094 380a4ea9ddc3ec3dd43ff1de4304914b 205 Gene3D G3DSA:3.30.1330.130 8 156 2.2E-39 T 23-10-2018 Mlab_1094 380a4ea9ddc3ec3dd43ff1de4304914b 205 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 22 156 8.6E-39 T 23-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain Mlab_0516 be4dcd7eff5a467797d95ff64178a53b 162 SUPERFAMILY SSF48452 5 141 2.59E-26 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0516 be4dcd7eff5a467797d95ff64178a53b 162 SMART SM00028 38 71 0.34 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0516 be4dcd7eff5a467797d95ff64178a53b 162 SMART SM00028 4 37 17.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0516 be4dcd7eff5a467797d95ff64178a53b 162 SMART SM00028 111 144 2.3 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0516 be4dcd7eff5a467797d95ff64178a53b 162 SMART SM00028 72 105 14.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0516 be4dcd7eff5a467797d95ff64178a53b 162 Pfam PF13432 Tetratricopeptide repeat 10 71 8.4E-8 T 23-10-2018 Mlab_0516 be4dcd7eff5a467797d95ff64178a53b 162 Pfam PF13432 Tetratricopeptide repeat 76 139 4.2E-9 T 23-10-2018 Mlab_0516 be4dcd7eff5a467797d95ff64178a53b 162 Gene3D G3DSA:1.25.40.10 4 161 3.3E-25 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1207 d9cd58e14e27c4918262f478eee25cb1 481 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 5 336 2.6E-75 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Mlab_1207 d9cd58e14e27c4918262f478eee25cb1 481 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 5 473 41.033 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 Mlab_1207 d9cd58e14e27c4918262f478eee25cb1 481 Gene3D G3DSA:3.20.20.105 1 355 8.0E-103 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Mlab_1207 d9cd58e14e27c4918262f478eee25cb1 481 SUPERFAMILY SSF51713 1 353 3.79E-105 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Mlab_1207 d9cd58e14e27c4918262f478eee25cb1 481 Pfam PF01702 Queuine tRNA-ribosyltransferase 110 329 2.2E-38 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Mlab_1207 d9cd58e14e27c4918262f478eee25cb1 481 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 5 440 3.3E-150 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 Mlab_1207 d9cd58e14e27c4918262f478eee25cb1 481 SUPERFAMILY SSF88802 358 438 7.19E-7 T 23-10-2018 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 10 560 3.1E-191 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 10 558 35.366 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 SUPERFAMILY SSF50715 408 557 1.36E-21 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 Gene3D G3DSA:3.40.50.620 93 407 1.7E-104 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 408 546 9.4E-25 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 SUPERFAMILY SSF52374 102 413 7.24E-82 T 23-10-2018 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 Gene3D G3DSA:2.40.240.10 417 506 8.8E-37 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 102 404 2.8E-69 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 Gene3D G3DSA:2.40.240.100 408 559 8.8E-37 T 23-10-2018 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 105 117 6.9E-20 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 119 130 6.9E-20 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 134 147 6.9E-20 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 279 289 6.9E-20 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 295 303 6.9E-20 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Mlab_0747 0b02e236d93236d1e8117acdf44f37a0 560 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 108 119 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0185 3e44050a876d0de0d70ee6d719d88f83 335 Pfam PF00293 NUDIX domain 197 319 3.4E-10 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Mlab_0185 3e44050a876d0de0d70ee6d719d88f83 335 Pfam PF12724 Flavodoxin domain 5 133 3.2E-26 T 23-10-2018 IPR026816 Flavodoxin domain Mlab_0185 3e44050a876d0de0d70ee6d719d88f83 335 Gene3D G3DSA:3.40.50.360 2 124 8.6E-13 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0185 3e44050a876d0de0d70ee6d719d88f83 335 SUPERFAMILY SSF55811 166 327 6.09E-37 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Mlab_0185 3e44050a876d0de0d70ee6d719d88f83 335 Gene3D G3DSA:3.90.79.10 163 334 1.1E-42 T 23-10-2018 Mlab_0185 3e44050a876d0de0d70ee6d719d88f83 335 ProSitePatterns PS00893 Nudix box signature. 231 252 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Mlab_0185 3e44050a876d0de0d70ee6d719d88f83 335 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 23-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 Mlab_0185 3e44050a876d0de0d70ee6d719d88f83 335 SUPERFAMILY SSF52218 3 132 2.58E-17 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1173 38dedad6f2efbc5b5713306ce84fb872 177 Pfam PF01381 Helix-turn-helix 97 146 2.4E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_1173 38dedad6f2efbc5b5713306ce84fb872 177 SUPERFAMILY SSF47413 91 146 1.51E-9 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Mlab_1173 38dedad6f2efbc5b5713306ce84fb872 177 SMART SM00530 96 151 1.7E-4 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_1173 38dedad6f2efbc5b5713306ce84fb872 177 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 10 176 3.0E-28 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 Mlab_1173 38dedad6f2efbc5b5713306ce84fb872 177 Gene3D G3DSA:1.10.260.40 84 177 2.7E-13 T 23-10-2018 Mlab_0679 ad580cc90518fd5f8aa4209ce5af0056 310 Pfam PF04055 Radical SAM superfamily 47 227 2.6E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0679 ad580cc90518fd5f8aa4209ce5af0056 310 SMART SM00729 41 264 9.5E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_0679 ad580cc90518fd5f8aa4209ce5af0056 310 SUPERFAMILY SSF102114 38 281 2.75E-40 T 23-10-2018 Mlab_0679 ad580cc90518fd5f8aa4209ce5af0056 310 TIGRFAM TIGR01290 nifB: nitrogenase cofactor biosynthesis protein NifB 20 294 3.5E-112 T 23-10-2018 IPR005980 Nitrogenase cofactor biosynthesis protein NifB GO:0009108|GO:0009399 Mlab_0679 ad580cc90518fd5f8aa4209ce5af0056 310 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 47 58 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_0679 ad580cc90518fd5f8aa4209ce5af0056 310 Pfam PF13394 4Fe-4S single cluster domain 50 138 5.5E-5 T 23-10-2018 Mlab_0679 ad580cc90518fd5f8aa4209ce5af0056 310 Gene3D G3DSA:3.20.20.70 36 302 1.1E-36 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0021 ca0a16541089384dd75e77f51b82edd3 382 Pfam PF13535 ATP-grasp domain 119 276 2.7E-63 T 23-10-2018 Mlab_0021 ca0a16541089384dd75e77f51b82edd3 382 Gene3D G3DSA:3.30.470.20 80 344 1.4E-31 T 23-10-2018 Mlab_0021 ca0a16541089384dd75e77f51b82edd3 382 SUPERFAMILY SSF56059 116 292 2.3E-22 T 23-10-2018 Mlab_0207 f1eff3c549de8eacea5d19f98c04a746 376 Gene3D G3DSA:3.90.1150.10 26 372 2.2E-119 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_0207 f1eff3c549de8eacea5d19f98c04a746 376 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Mlab_0207 f1eff3c549de8eacea5d19f98c04a746 376 SUPERFAMILY SSF53383 1 375 4.21E-105 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_0207 f1eff3c549de8eacea5d19f98c04a746 376 Gene3D G3DSA:3.40.640.10 63 280 2.2E-119 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_0207 f1eff3c549de8eacea5d19f98c04a746 376 Pfam PF00155 Aminotransferase class I and II 32 372 2.0E-65 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Mlab_0719 abf22da5f634c3242353d53b3cf87629 316 SUPERFAMILY SSF161098 95 298 2.88E-25 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0719 abf22da5f634c3242353d53b3cf87629 316 Gene3D G3DSA:1.10.3720.10 88 304 3.9E-32 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0719 abf22da5f634c3242353d53b3cf87629 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 311 2.8E-43 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SUPERFAMILY SSF52540 153 365 6.73E-6 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SUPERFAMILY SSF48452 1046 1161 9.2E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SMART SM00028 1047 1080 0.039 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SMART SM00028 1199 1232 0.018 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SMART SM00028 1275 1308 0.96 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SMART SM00028 1238 1271 66.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SMART SM00028 1123 1156 0.0038 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SMART SM00028 1086 1119 50.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SMART SM00028 879 923 79.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SMART SM00028 1162 1195 290.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SUPERFAMILY SSF48452 784 962 1.21E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 Gene3D G3DSA:1.25.40.10 1165 1309 3.0E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 Gene3D G3DSA:1.25.40.10 1011 1164 3.2E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 Gene3D G3DSA:1.25.40.10 772 977 1.9E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 SUPERFAMILY SSF48452 1123 1307 1.71E-22 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 Pfam PF13181 Tetratricopeptide repeat 1055 1079 0.081 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 Pfam PF13181 Tetratricopeptide repeat 1129 1155 0.0025 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0727 46b46c9a9fdc93792243e90d2d95465c 1310 Pfam PF13181 Tetratricopeptide repeat 1281 1307 0.17 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0026 d51beb75a9cc14840e8d9bcb1f2fbce2 647 SUPERFAMILY SSF52540 425 643 2.88E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0026 d51beb75a9cc14840e8d9bcb1f2fbce2 647 ProSitePatterns PS00211 ABC transporters family signature. 330 344 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0026 d51beb75a9cc14840e8d9bcb1f2fbce2 647 Pfam PF00005 ABC transporter 449 590 1.6E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0026 d51beb75a9cc14840e8d9bcb1f2fbce2 647 Pfam PF00005 ABC transporter 206 358 1.6E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0026 d51beb75a9cc14840e8d9bcb1f2fbce2 647 SUPERFAMILY SSF52540 190 413 1.09E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0026 d51beb75a9cc14840e8d9bcb1f2fbce2 647 Gene3D G3DSA:3.40.50.300 431 646 1.6E-59 T 23-10-2018 Mlab_0026 d51beb75a9cc14840e8d9bcb1f2fbce2 647 SMART SM00382 458 639 3.3E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0026 d51beb75a9cc14840e8d9bcb1f2fbce2 647 SMART SM00382 215 406 1.9E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0026 d51beb75a9cc14840e8d9bcb1f2fbce2 647 Gene3D G3DSA:3.40.50.300 188 430 2.0E-59 T 23-10-2018 Mlab_1201 bcef0e705aab4f43c989076e1bbf8846 636 PIRSF PIRSF015855 9 624 9.0E-164 T 23-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Mlab_1201 bcef0e705aab4f43c989076e1bbf8846 636 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 119 131 2.1E-11 T 23-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Mlab_1201 bcef0e705aab4f43c989076e1bbf8846 636 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 412 426 2.1E-11 T 23-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Mlab_1201 bcef0e705aab4f43c989076e1bbf8846 636 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 182 201 2.1E-11 T 23-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Mlab_1201 bcef0e705aab4f43c989076e1bbf8846 636 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 122 128 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Mlab_1201 bcef0e705aab4f43c989076e1bbf8846 636 Pfam PF01555 DNA methylase 119 441 2.5E-35 T 23-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 Mlab_1201 bcef0e705aab4f43c989076e1bbf8846 636 SUPERFAMILY SSF53335 87 467 1.48E-63 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1407 5c98125caa848b468a1e7dd9f813f005 191 SUPERFAMILY SSF53335 21 167 1.15E-27 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1407 5c98125caa848b468a1e7dd9f813f005 191 Gene3D G3DSA:3.40.50.150 18 176 2.1E-34 T 23-10-2018 Mlab_1407 5c98125caa848b468a1e7dd9f813f005 191 Pfam PF08241 Methyltransferase domain 31 116 1.5E-17 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Mlab_0102 df0c8a396372c142d79953e19a110495 153 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 153 83.128 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 Mlab_0102 df0c8a396372c142d79953e19a110495 153 ProSitePatterns PS00634 Ribosomal protein L30 signature. 20 52 - T 23-10-2018 IPR018038 Ribosomal protein L30, conserved site Mlab_0102 df0c8a396372c142d79953e19a110495 153 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 2 153 3.2E-62 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 Mlab_0102 df0c8a396372c142d79953e19a110495 153 Gene3D G3DSA:1.10.15.30 58 113 4.7E-56 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type Mlab_0102 df0c8a396372c142d79953e19a110495 153 Pfam PF00327 Ribosomal protein L30p/L7e 2 52 1.4E-15 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain Mlab_0102 df0c8a396372c142d79953e19a110495 153 Gene3D G3DSA:3.30.1390.20 3 140 4.7E-56 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily Mlab_0102 df0c8a396372c142d79953e19a110495 153 SUPERFAMILY SSF55129 1 152 8.89E-47 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily Mlab_0020 62a10220eba5dca1f60c3d316fe3ba92 493 Gene3D G3DSA:1.10.10.10 338 492 2.6E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0020 62a10220eba5dca1f60c3d316fe3ba92 493 Gene3D G3DSA:3.40.50.300 201 335 2.8E-41 T 23-10-2018 Mlab_0020 62a10220eba5dca1f60c3d316fe3ba92 493 SUPERFAMILY SSF52540 58 347 2.33E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0020 62a10220eba5dca1f60c3d316fe3ba92 493 SMART SM00490 245 326 2.0E-26 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0020 62a10220eba5dca1f60c3d316fe3ba92 493 Gene3D G3DSA:3.40.50.300 1 200 9.6E-81 T 23-10-2018 Mlab_0020 62a10220eba5dca1f60c3d316fe3ba92 493 Pfam PF00270 DEAD/DEAH box helicase 20 179 2.5E-20 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Mlab_0020 62a10220eba5dca1f60c3d316fe3ba92 493 Pfam PF00271 Helicase conserved C-terminal domain 223 325 1.6E-16 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0020 62a10220eba5dca1f60c3d316fe3ba92 493 Pfam PF16124 RecQ zinc-binding 338 398 1.4E-16 T 23-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain Mlab_0020 62a10220eba5dca1f60c3d316fe3ba92 493 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 458 1.2E-153 T 23-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 Mlab_0020 62a10220eba5dca1f60c3d316fe3ba92 493 SMART SM00487 14 210 3.8E-31 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Mlab_1358 2910b0015539d4fc771eb77d6bb02b5e 212 Pfam PF01983 Guanylyl transferase CofC like 5 200 2.9E-45 T 23-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 Mlab_1358 2910b0015539d4fc771eb77d6bb02b5e 212 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 3 191 27.137 T 23-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 Mlab_1358 2910b0015539d4fc771eb77d6bb02b5e 212 SUPERFAMILY SSF53448 3 203 2.69E-44 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1358 2910b0015539d4fc771eb77d6bb02b5e 212 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 5 184 2.0E-50 T 23-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 Mlab_1358 2910b0015539d4fc771eb77d6bb02b5e 212 Gene3D G3DSA:3.90.550.10 2 163 4.5E-35 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0252 626bb61af73e1d9ae7e815c980cc3e40 316 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 45 173 1.1E-60 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Mlab_0252 626bb61af73e1d9ae7e815c980cc3e40 316 SUPERFAMILY SSF52540 13 291 1.07E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0252 626bb61af73e1d9ae7e815c980cc3e40 316 SMART SM00382 41 182 2.0E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0252 626bb61af73e1d9ae7e815c980cc3e40 316 PIRSF PIRSF002849 6 316 2.7E-125 T 23-10-2018 Mlab_0252 626bb61af73e1d9ae7e815c980cc3e40 316 Gene3D G3DSA:1.10.8.300 204 313 1.6E-34 T 23-10-2018 Mlab_0252 626bb61af73e1d9ae7e815c980cc3e40 316 Gene3D G3DSA:3.40.50.300 25 191 4.5E-44 T 23-10-2018 Mlab_0366 08d3158118900fe81f9ef05b2f15d000 78 Gene3D G3DSA:2.40.50.970 1 75 3.6E-24 T 23-10-2018 IPR037254 HupF/HypC superfamily Mlab_0366 08d3158118900fe81f9ef05b2f15d000 78 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 77 9.8E-22 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC Mlab_0366 08d3158118900fe81f9ef05b2f15d000 78 SUPERFAMILY SSF159127 1 76 1.7E-22 T 23-10-2018 IPR037254 HupF/HypC superfamily Mlab_0366 08d3158118900fe81f9ef05b2f15d000 78 Pfam PF01455 HupF/HypC family 1 65 1.2E-22 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC Mlab_0366 08d3158118900fe81f9ef05b2f15d000 78 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 2.5E-7 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC Mlab_0366 08d3158118900fe81f9ef05b2f15d000 78 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 2.5E-7 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC Mlab_0366 08d3158118900fe81f9ef05b2f15d000 78 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 2.5E-7 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC Mlab_1023 e02ca2edb149f0a340ab9bac0d56fea5 269 SUPERFAMILY SSF161098 4 256 1.02E-43 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1023 e02ca2edb149f0a340ab9bac0d56fea5 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 258 8.6E-19 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_1023 e02ca2edb149f0a340ab9bac0d56fea5 269 Gene3D G3DSA:1.10.3720.10 8 262 6.3E-61 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0001 88c93b61928c6dd265bb9e75d1c7fadd 425 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 63 212 1.5E-10 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_0001 88c93b61928c6dd265bb9e75d1c7fadd 425 SUPERFAMILY SSF52540 21 299 1.33E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0001 88c93b61928c6dd265bb9e75d1c7fadd 425 SMART SM01074 320 402 1.5E-31 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 Mlab_0001 88c93b61928c6dd265bb9e75d1c7fadd 425 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 21 389 9.5E-135 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea Mlab_0001 88c93b61928c6dd265bb9e75d1c7fadd 425 Gene3D G3DSA:1.10.10.10 312 411 2.6E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0001 88c93b61928c6dd265bb9e75d1c7fadd 425 SMART SM00382 59 226 1.6E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0001 88c93b61928c6dd265bb9e75d1c7fadd 425 Gene3D G3DSA:3.40.50.300 37 224 1.7E-100 T 23-10-2018 Mlab_0001 88c93b61928c6dd265bb9e75d1c7fadd 425 Pfam PF09079 CDC6, C terminal winged helix domain 320 400 4.5E-21 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 Mlab_0001 88c93b61928c6dd265bb9e75d1c7fadd 425 SUPERFAMILY SSF46785 305 411 3.54E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0001 88c93b61928c6dd265bb9e75d1c7fadd 425 Hamap MF_01407 ORC1-type DNA replication protein. 14 402 31.145 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea Mlab_0001 88c93b61928c6dd265bb9e75d1c7fadd 425 Gene3D G3DSA:1.10.8.60 21 303 1.7E-100 T 23-10-2018 Mlab_1402 9172b75c8710dea09930c3db7f12400f 267 Pfam PF09754 PAC2 family 46 246 1.6E-36 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 Mlab_1402 9172b75c8710dea09930c3db7f12400f 267 Gene3D G3DSA:3.40.50.10900 31 256 4.1E-46 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily Mlab_1402 9172b75c8710dea09930c3db7f12400f 267 SUPERFAMILY SSF159659 32 252 6.02E-32 T 23-10-2018 Mlab_1025 5ddbc92a7552478041a5ceee8f28bfba 328 Gene3D G3DSA:3.40.190.10 29 315 1.1E-103 T 23-10-2018 Mlab_1025 5ddbc92a7552478041a5ceee8f28bfba 328 Pfam PF13531 Bacterial extracellular solute-binding protein 30 315 9.6E-30 T 23-10-2018 Mlab_1025 5ddbc92a7552478041a5ceee8f28bfba 328 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 28 313 6.1E-112 T 23-10-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 Mlab_1025 5ddbc92a7552478041a5ceee8f28bfba 328 Gene3D G3DSA:3.40.190.10 113 290 1.1E-103 T 23-10-2018 Mlab_1025 5ddbc92a7552478041a5ceee8f28bfba 328 SUPERFAMILY SSF53850 26 325 2.35E-37 T 23-10-2018 Mlab_1138 da65c4dc3af25fbb10ad84f4938f1d01 226 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 7 221 1.9E-57 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 Mlab_1138 da65c4dc3af25fbb10ad84f4938f1d01 226 SUPERFAMILY SSF51395 2 214 2.2E-48 T 23-10-2018 Mlab_1138 da65c4dc3af25fbb10ad84f4938f1d01 226 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 2 224 26.538 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 Mlab_1138 da65c4dc3af25fbb10ad84f4938f1d01 226 TIGRFAM TIGR04146 GGGPS_Afulg: phosphoglycerol geranylgeranyltransferase 3 222 2.1E-107 T 23-10-2018 IPR026438 Geranylgeranylglyceryl phosphate synthase, archaea GO:0002094|GO:0046474 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 Mlab_1138 da65c4dc3af25fbb10ad84f4938f1d01 226 Gene3D G3DSA:3.20.20.390 1 226 2.5E-77 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily Mlab_1138 da65c4dc3af25fbb10ad84f4938f1d01 226 Pfam PF01884 PcrB family 1 223 1.8E-59 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 Mlab_0699 bcf17c76eb866c066c08453f72bec212 121 Gene3D G3DSA:2.60.120.10 19 117 4.5E-32 T 23-10-2018 IPR014710 RmlC-like jelly roll fold Mlab_0699 bcf17c76eb866c066c08453f72bec212 121 Pfam PF07883 Cupin domain 56 119 2.5E-11 T 23-10-2018 IPR013096 Cupin 2, conserved barrel Mlab_0699 bcf17c76eb866c066c08453f72bec212 121 SUPERFAMILY SSF51182 22 119 1.6E-22 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily Mlab_1478 d7f62934c51592e77b863ac3c085078c 222 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 222 74.687 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 Mlab_1478 d7f62934c51592e77b863ac3c085078c 222 Gene3D G3DSA:3.75.10.10 1 221 2.0E-61 T 23-10-2018 Mlab_1478 d7f62934c51592e77b863ac3c085078c 222 SUPERFAMILY SSF55909 4 221 1.67E-55 T 23-10-2018 Mlab_1478 d7f62934c51592e77b863ac3c085078c 222 Pfam PF01912 eIF-6 family 5 201 5.8E-63 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 Mlab_1478 d7f62934c51592e77b863ac3c085078c 222 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 6 221 6.5E-58 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 Mlab_1478 d7f62934c51592e77b863ac3c085078c 222 SMART SM00654 3 201 4.8E-51 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 Mlab_0279 223be705d9b215f9438ea0d49684f7f6 301 Gene3D G3DSA:1.20.1640.10 95 293 6.5E-12 T 23-10-2018 Mlab_0279 223be705d9b215f9438ea0d49684f7f6 301 SUPERFAMILY SSF82866 112 270 4.19E-22 T 23-10-2018 Mlab_0279 223be705d9b215f9438ea0d49684f7f6 301 Pfam PF07549 SecD/SecF GG Motif 35 61 2.1E-4 T 23-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site Mlab_0279 223be705d9b215f9438ea0d49684f7f6 301 Pfam PF02355 Protein export membrane protein 108 278 2.2E-30 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Mlab_0279 223be705d9b215f9438ea0d49684f7f6 301 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 9 284 28.277 T 23-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 127 138 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 Gene3D G3DSA:3.30.70.20 157 193 2.0E-5 T 23-10-2018 Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 Pfam PF00037 4Fe-4S binding domain 121 142 1.8E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 Pfam PF00037 4Fe-4S binding domain 171 188 6.1E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 Gene3D G3DSA:3.30.70.20 280 355 2.1E-9 T 23-10-2018 Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 39 50 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 Gene3D G3DSA:3.30.70.3270 195 279 7.7E-12 T 23-10-2018 Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 SUPERFAMILY SSF54862 33 342 2.83E-27 T 23-10-2018 Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 Pfam PF12838 4Fe-4S dicluster domain 215 266 3.2E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 Pfam PF12838 4Fe-4S dicluster domain 287 338 9.8E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 Pfam PF12838 4Fe-4S dicluster domain 39 94 2.1E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 252 263 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 326 337 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 PIRSF PIRSF005658 9 387 2.2E-79 T 23-10-2018 Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 Gene3D G3DSA:3.30.70.20 108 146 1.1E-5 T 23-10-2018 Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 Gene3D G3DSA:3.30.70.20 18 57 2.0E-5 T 23-10-2018 Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 Gene3D G3DSA:3.30.70.20 58 100 3.6E-5 T 23-10-2018 Mlab_0238 67ace01eca70be1a4e3b61b05fd30e54 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 215 226 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_1057 205c73fa733247eb1ae566b7be86fe1b 390 Gene3D G3DSA:3.40.228.10 117 194 2.1E-7 T 23-10-2018 Mlab_1057 205c73fa733247eb1ae566b7be86fe1b 390 Gene3D G3DSA:3.40.50.740 200 384 2.8E-22 T 23-10-2018 Mlab_1057 205c73fa733247eb1ae566b7be86fe1b 390 Gene3D G3DSA:3.40.50.740 68 116 2.1E-7 T 23-10-2018 Mlab_1057 205c73fa733247eb1ae566b7be86fe1b 390 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 3 53 1.5E-13 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_1057 205c73fa733247eb1ae566b7be86fe1b 390 Pfam PF00384 Molybdopterin oxidoreductase 251 337 2.3E-7 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_1057 205c73fa733247eb1ae566b7be86fe1b 390 Gene3D G3DSA:2.20.25.90 3 56 3.4E-13 T 23-10-2018 Mlab_1057 205c73fa733247eb1ae566b7be86fe1b 390 SMART SM00926 3 57 1.2E-12 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_1057 205c73fa733247eb1ae566b7be86fe1b 390 SUPERFAMILY SSF53706 3 377 1.15E-64 T 23-10-2018 Mlab_1057 205c73fa733247eb1ae566b7be86fe1b 390 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 8 25 - T 23-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 Mlab_0543 ae3c3359fd6037b5de29bc40832052fa 187 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 177 9.2E-55 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 Mlab_0543 ae3c3359fd6037b5de29bc40832052fa 187 Gene3D G3DSA:2.70.40.10 1 182 1.2E-53 T 23-10-2018 IPR036157 dUTPase-like superfamily Mlab_0543 ae3c3359fd6037b5de29bc40832052fa 187 Hamap MF_00146 dCTP deaminase [dcd]. 1 178 29.176 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 Mlab_0543 ae3c3359fd6037b5de29bc40832052fa 187 SUPERFAMILY SSF51283 1 179 5.89E-51 T 23-10-2018 IPR036157 dUTPase-like superfamily Mlab_0543 ae3c3359fd6037b5de29bc40832052fa 187 Pfam PF00692 dUTPase 68 174 1.4E-10 T 23-10-2018 IPR029054 dUTPase-like Mlab_0380 cb82419e962cd7692af93b97dd0cfb93 259 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 30 239 1.2E-52 T 23-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 Mlab_0380 cb82419e962cd7692af93b97dd0cfb93 259 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 29 244 25.935 T 23-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 Mlab_0380 cb82419e962cd7692af93b97dd0cfb93 259 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 29 242 1.4E-73 T 23-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 Mlab_0380 cb82419e962cd7692af93b97dd0cfb93 259 Gene3D G3DSA:1.10.1760.20 29 238 7.4E-52 T 23-10-2018 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 3 589 42.273 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 Gene3D G3DSA:2.40.30.10 232 344 7.7E-37 T 23-10-2018 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 159 1.6E-16 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 SUPERFAMILY SSF52156 330 451 1.7E-22 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 Gene3D G3DSA:2.40.30.10 461 549 4.4E-30 T 23-10-2018 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 Pfam PF03144 Elongation factor Tu domain 2 245 322 3.0E-7 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 Pfam PF00009 Elongation factor Tu GTP binding domain 8 214 8.7E-28 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 Pfam PF14578 Elongation factor Tu domain 4 462 546 1.1E-28 T 23-10-2018 IPR029459 Elongation factor Tu-type domain Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 PRINTS PR00315 GTP-binding elongation factor signature 88 99 6.8E-8 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 PRINTS PR00315 GTP-binding elongation factor signature 72 82 6.8E-8 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 PRINTS PR00315 GTP-binding elongation factor signature 9 22 6.8E-8 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 PRINTS PR00315 GTP-binding elongation factor signature 124 133 6.8E-8 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 SUPERFAMILY SSF50447 460 585 3.34E-27 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 SUPERFAMILY SSF52540 6 291 7.09E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 Gene3D G3DSA:3.40.50.10050 345 452 2.4E-25 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 5 589 3.7E-222 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 Gene3D G3DSA:3.40.50.300 1 225 7.4E-61 T 23-10-2018 Mlab_1520 5506b435f097b742d2c587456bfbdb6a 589 Pfam PF11987 Translation-initiation factor 2 337 440 5.8E-16 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 Mlab_1534 75d6e546fcc9eb946f55a2458f6f1844 211 Pfam PF07790 Archaeal Type IV pilin, N-terminal 16 89 3.9E-18 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 5 363 38.821 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 Gene3D G3DSA:3.40.1360.10 140 363 2.3E-74 T 23-10-2018 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 37 57 1.8E-39 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 334 357 1.8E-39 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 166 184 1.8E-39 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 222 242 1.8E-39 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 107 124 1.8E-39 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 Gene3D G3DSA:1.10.10.10 2 139 2.7E-45 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 SUPERFAMILY SSF56726 72 361 2.88E-80 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 Pfam PF04406 Type IIB DNA topoisomerase 73 135 3.5E-15 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 192 209 6.0E-13 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 248 264 6.0E-13 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 113 130 6.0E-13 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 Mlab_0417 fbf5f448f6d96dccb6501eb83e1b2293 365 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 216 237 6.0E-13 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 Mlab_0521 9ba4996fabb31d8f0b6d952187e1901b 467 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 187 6.3E-15 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Mlab_0521 9ba4996fabb31d8f0b6d952187e1901b 467 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 1 443 37.253 T 23-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 Mlab_0521 9ba4996fabb31d8f0b6d952187e1901b 467 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 438 4.2E-36 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 Mlab_0521 9ba4996fabb31d8f0b6d952187e1901b 467 Gene3D G3DSA:3.40.50.880 253 428 4.1E-7 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0521 9ba4996fabb31d8f0b6d952187e1901b 467 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 448 6.2E-123 T 23-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 Mlab_0521 9ba4996fabb31d8f0b6d952187e1901b 467 Gene3D G3DSA:3.40.50.300 1 189 4.5E-23 T 23-10-2018 Mlab_0521 9ba4996fabb31d8f0b6d952187e1901b 467 SUPERFAMILY SSF52540 1 193 1.71E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0521 9ba4996fabb31d8f0b6d952187e1901b 467 SUPERFAMILY SSF52317 249 443 4.09E-28 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0273 8309cf615ee3bac09742e18be7c6a003 111 Pfam PF04434 SWIM zinc finger 48 86 2.4E-4 T 23-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 Gene3D G3DSA:3.50.50.60 203 330 1.3E-87 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 Gene3D G3DSA:3.40.30.10 2 86 3.2E-21 T 23-10-2018 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 Gene3D G3DSA:3.50.50.60 94 390 1.3E-87 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 371 1.1E-29 T 23-10-2018 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 114 1.1E-29 T 23-10-2018 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 191 209 1.1E-29 T 23-10-2018 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 322 338 1.1E-29 T 23-10-2018 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 251 1.1E-29 T 23-10-2018 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 Pfam PF00462 Glutaredoxin 5 62 5.0E-16 T 23-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 221 241 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 93 374 5.0E-38 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 156 5.0E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 229 253 5.0E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 94 116 5.0E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 141 5.0E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 192 200 5.0E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 226 5.0E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 324 345 5.0E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 359 377 5.0E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 SUPERFAMILY SSF51905 84 396 4.14E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_1501 be50a45ce31b1aedc313eee986fcc8e2 398 SUPERFAMILY SSF52833 3 72 1.89E-16 T 23-10-2018 IPR036249 Thioredoxin-like superfamily Mlab_0520 912f54c382c5df126a8e4165169cf350 353 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 25 107 2.4E-16 T 23-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 Mlab_0520 912f54c382c5df126a8e4165169cf350 353 TIGRFAM TIGR03282 methan_mark_13: putative methanogenesis marker 13 metalloprotein 5 352 2.2E-146 T 23-10-2018 IPR017675 Ni-sirohydrochlorin a,c-diamide reductive cyclase complex, component CfbD KEGG: 00860+6.3.3.7|MetaCyc: PWY-5196 Mlab_0520 912f54c382c5df126a8e4165169cf350 353 SUPERFAMILY SSF53807 4 134 8.18E-28 T 23-10-2018 Mlab_0520 912f54c382c5df126a8e4165169cf350 353 Gene3D G3DSA:3.40.50.1980 9 137 7.2E-23 T 23-10-2018 Mlab_0177 71029a46e4c98317f0ee23adc6a2f387 471 SUPERFAMILY SSF102114 111 396 1.2E-48 T 23-10-2018 Mlab_0177 71029a46e4c98317f0ee23adc6a2f387 471 Pfam PF04055 Radical SAM superfamily 118 247 2.5E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0177 71029a46e4c98317f0ee23adc6a2f387 471 Gene3D G3DSA:3.20.20.70 111 382 1.5E-35 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0425 0346388fb71df55ab3fb478b1c30409a 283 PIRSF PIRSF036979 1 281 9.0E-78 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 Mlab_0425 0346388fb71df55ab3fb478b1c30409a 283 SUPERFAMILY SSF52768 8 279 5.04E-72 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily Mlab_0425 0346388fb71df55ab3fb478b1c30409a 283 TIGRFAM TIGR01230 agmatinase: agmatinase 8 276 4.0E-67 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 Mlab_0425 0346388fb71df55ab3fb478b1c30409a 283 Gene3D G3DSA:3.40.800.10 1 282 6.9E-80 T 23-10-2018 Mlab_0425 0346388fb71df55ab3fb478b1c30409a 283 Pfam PF00491 Arginase family 21 275 4.2E-67 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 Mlab_0368 0742a7de72cbfc634ce93400e67fd596 251 Pfam PF06508 Queuosine biosynthesis protein QueC 13 76 6.6E-5 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Mlab_0368 0742a7de72cbfc634ce93400e67fd596 251 PIRSF PIRSF006661 1 251 2.0E-59 T 23-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 Mlab_0368 0742a7de72cbfc634ce93400e67fd596 251 SUPERFAMILY SSF52402 12 175 1.76E-28 T 23-10-2018 Mlab_0368 0742a7de72cbfc634ce93400e67fd596 251 Gene3D G3DSA:3.40.50.620 3 157 9.4E-24 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0368 0742a7de72cbfc634ce93400e67fd596 251 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 3 235 2.3E-52 T 23-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 Mlab_1260 3fc98a9fa8ecf1df85cabfc6f5d41964 461 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 36 117 8.1E-29 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Mlab_1260 3fc98a9fa8ecf1df85cabfc6f5d41964 461 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 251 266 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Mlab_1260 3fc98a9fa8ecf1df85cabfc6f5d41964 461 Gene3D G3DSA:3.10.20.70 24 126 8.3E-36 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Mlab_1260 3fc98a9fa8ecf1df85cabfc6f5d41964 461 Gene3D G3DSA:3.30.590.10 127 461 2.7E-129 T 23-10-2018 Mlab_1260 3fc98a9fa8ecf1df85cabfc6f5d41964 461 SUPERFAMILY SSF54368 25 123 7.72E-29 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Mlab_1260 3fc98a9fa8ecf1df85cabfc6f5d41964 461 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 28 458 2.0E-159 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Mlab_1260 3fc98a9fa8ecf1df85cabfc6f5d41964 461 Pfam PF00120 Glutamine synthetase, catalytic domain 125 457 5.0E-127 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Mlab_1260 3fc98a9fa8ecf1df85cabfc6f5d41964 461 SMART SM01230 124 371 1.9E-133 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Mlab_1260 3fc98a9fa8ecf1df85cabfc6f5d41964 461 ProSitePatterns PS00180 Glutamine synthetase signature 1. 71 89 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Mlab_1260 3fc98a9fa8ecf1df85cabfc6f5d41964 461 SUPERFAMILY SSF55931 126 458 1.28E-120 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Mlab_0619 334f9ac563c46956fe58393a22556fdf 290 SMART SM00729 12 235 0.0046 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_0619 334f9ac563c46956fe58393a22556fdf 290 SUPERFAMILY SSF102114 17 200 2.62E-12 T 23-10-2018 Mlab_0619 334f9ac563c46956fe58393a22556fdf 290 Gene3D G3DSA:3.80.30.30 49 257 2.7E-7 T 23-10-2018 Mlab_0619 334f9ac563c46956fe58393a22556fdf 290 Pfam PF04055 Radical SAM superfamily 17 181 3.9E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_1080 da18a184ecb3390476598f5bfd3e66be 253 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 210 7.8E-38 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Mlab_1080 da18a184ecb3390476598f5bfd3e66be 253 SUPERFAMILY SSF53790 1 251 3.14E-50 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Mlab_1080 da18a184ecb3390476598f5bfd3e66be 253 Gene3D G3DSA:3.40.1010.10 1 111 8.7E-25 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Mlab_1080 da18a184ecb3390476598f5bfd3e66be 253 Gene3D G3DSA:3.30.950.10 112 246 2.8E-44 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Mlab_1080 da18a184ecb3390476598f5bfd3e66be 253 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 4 247 4.8E-81 T 23-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 Mlab_0603 d2c1fb68e107d18ac73d8fd5d3a7216c 522 Pfam PF08502 LeuA allosteric (dimerisation) domain 383 514 3.3E-26 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_0603 d2c1fb68e107d18ac73d8fd5d3a7216c 522 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 214 227 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_0603 d2c1fb68e107d18ac73d8fd5d3a7216c 522 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 34 50 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_0603 d2c1fb68e107d18ac73d8fd5d3a7216c 522 Pfam PF00682 HMGL-like 26 285 3.1E-88 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Mlab_0603 d2c1fb68e107d18ac73d8fd5d3a7216c 522 SUPERFAMILY SSF51569 22 303 4.58E-94 T 23-10-2018 Mlab_0603 d2c1fb68e107d18ac73d8fd5d3a7216c 522 Gene3D G3DSA:3.20.20.70 23 288 3.4E-101 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0603 d2c1fb68e107d18ac73d8fd5d3a7216c 522 Gene3D G3DSA:3.30.160.270 409 516 1.1E-9 T 23-10-2018 Mlab_0603 d2c1fb68e107d18ac73d8fd5d3a7216c 522 SMART SM00917 382 515 9.1E-27 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_0603 d2c1fb68e107d18ac73d8fd5d3a7216c 522 Gene3D G3DSA:1.10.238.260 293 408 1.1E-26 T 23-10-2018 Mlab_0603 d2c1fb68e107d18ac73d8fd5d3a7216c 522 SUPERFAMILY SSF110921 409 513 1.83E-20 T 23-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_1575 8f1495186cfb71e24772cb507cdf2a52 903 Pfam PF00271 Helicase conserved C-terminal domain 428 527 3.8E-15 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_1575 8f1495186cfb71e24772cb507cdf2a52 903 Pfam PF00270 DEAD/DEAH box helicase 214 377 9.1E-20 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Mlab_1575 8f1495186cfb71e24772cb507cdf2a52 903 SMART SM00487 208 406 1.1E-26 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Mlab_1575 8f1495186cfb71e24772cb507cdf2a52 903 SUPERFAMILY SSF52540 224 543 4.05E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1575 8f1495186cfb71e24772cb507cdf2a52 903 Gene3D G3DSA:1.25.40.10 799 875 5.9E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1575 8f1495186cfb71e24772cb507cdf2a52 903 SMART SM00490 447 529 6.5E-18 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_1575 8f1495186cfb71e24772cb507cdf2a52 903 Gene3D G3DSA:3.40.50.300 201 397 5.2E-39 T 23-10-2018 Mlab_1575 8f1495186cfb71e24772cb507cdf2a52 903 SUPERFAMILY SSF48452 809 873 1.09E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1575 8f1495186cfb71e24772cb507cdf2a52 903 Gene3D G3DSA:3.40.50.300 452 547 5.0E-27 T 23-10-2018 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 197 213 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 65 79 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 175 331 2.0E-48 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 4 125 1.2E-27 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 SUPERFAMILY SSF51735 175 334 2.85E-59 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 Gene3D G3DSA:3.40.50.720 177 336 2.9E-163 T 23-10-2018 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 3 408 1.6E-166 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 PIRSF PIRSF001109 1 408 5.3E-171 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 Gene3D G3DSA:3.40.50.1480 3 396 2.9E-163 T 23-10-2018 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 SUPERFAMILY SSF52283 3 408 2.95E-90 T 23-10-2018 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 SMART SM00996 1 407 1.1E-112 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 SMART SM00997 175 334 5.8E-99 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Mlab_1411 a6cd2c3e9bf07bc3c85eb2f8d969df9b 408 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 131 401 3.4E-23 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 Pfam PF00515 Tetratricopeptide repeat 279 307 3.8E-7 T 23-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 Pfam PF13181 Tetratricopeptide repeat 213 242 3.5E-4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 Pfam PF13181 Tetratricopeptide repeat 111 142 1.1E-4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 Pfam PF13181 Tetratricopeptide repeat 180 209 0.031 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 Pfam PF13181 Tetratricopeptide repeat 247 272 0.011 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 SUPERFAMILY SSF48452 44 314 3.75E-44 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 SMART SM00028 109 142 0.019 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 SMART SM00028 245 278 0.0035 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 SMART SM00028 177 210 7.1E-4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 SMART SM00028 279 312 8.6E-6 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 SMART SM00028 75 108 0.18 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 SMART SM00028 41 74 0.0036 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 SMART SM00028 211 244 9.5E-4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 Gene3D G3DSA:1.25.40.10 3 176 4.2E-27 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 Gene3D G3DSA:1.25.40.10 177 244 7.1E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 Gene3D G3DSA:1.25.40.10 245 330 4.4E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1311 110af25bc1bf67fa274358d804461e3f 331 Pfam PF13432 Tetratricopeptide repeat 46 108 5.1E-5 T 23-10-2018 Mlab_1565 f1686aa6af67ec2b616bcf4bf280c29c 437 Pfam PF02241 Methyl-coenzyme M reductase beta subunit, C-terminal domain 188 436 7.6E-133 T 23-10-2018 IPR022679 Methyl-coenzyme M reductase, beta subunit, C-terminal GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1565 f1686aa6af67ec2b616bcf4bf280c29c 437 TIGRFAM TIGR03257 met_CoM_red_bet: methyl-coenzyme M reductase, beta subunit 6 435 9.8E-186 T 23-10-2018 IPR003179 Methyl-coenzyme M reductase, beta subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1565 f1686aa6af67ec2b616bcf4bf280c29c 437 Gene3D G3DSA:3.30.70.470 45 190 2.0E-181 T 23-10-2018 IPR015823 Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 2 GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1565 f1686aa6af67ec2b616bcf4bf280c29c 437 SUPERFAMILY SSF55088 3 186 1.57E-74 T 23-10-2018 IPR009024 Methyl-coenzyme M reductase, ferredoxin-like fold GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1565 f1686aa6af67ec2b616bcf4bf280c29c 437 Gene3D G3DSA:1.20.840.10 4 436 2.0E-181 T 23-10-2018 IPR008924 Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1565 f1686aa6af67ec2b616bcf4bf280c29c 437 Pfam PF02783 Methyl-coenzyme M reductase beta subunit, N-terminal domain 6 185 3.3E-80 T 23-10-2018 IPR022680 Methyl-coenzyme M reductase, beta subunit, N-terminal GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1565 f1686aa6af67ec2b616bcf4bf280c29c 437 SUPERFAMILY SSF48081 188 437 2.43E-111 T 23-10-2018 IPR008924 Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_0948 75cf7660e3dd9e8ffc12843fb4562fe1 179 Pfam PF01899 Na+/H+ ion antiporter subunit 13 161 2.2E-31 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 Mlab_0948 75cf7660e3dd9e8ffc12843fb4562fe1 179 PIRSF PIRSF019239 1 179 9.3E-51 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 Mlab_0758 b9c62ebe2fdb7676b96ffbb4b0b5f961 90 Pfam PF05239 PRC-barrel domain 5 75 5.2E-12 T 23-10-2018 IPR027275 PRC-barrel domain Mlab_0758 b9c62ebe2fdb7676b96ffbb4b0b5f961 90 Gene3D G3DSA:2.30.30.240 1 76 1.3E-10 T 23-10-2018 Mlab_0758 b9c62ebe2fdb7676b96ffbb4b0b5f961 90 SUPERFAMILY SSF50346 3 76 9.73E-13 T 23-10-2018 IPR011033 PRC-barrel-like superfamily Mlab_1093 30ef804ec4b61b21b342a02e06a58ac9 376 SUPERFAMILY SSF53807 32 335 5.1E-51 T 23-10-2018 Mlab_1093 30ef804ec4b61b21b342a02e06a58ac9 376 Gene3D G3DSA:3.40.50.1980 179 376 7.4E-62 T 23-10-2018 Mlab_1093 30ef804ec4b61b21b342a02e06a58ac9 376 Pfam PF01497 Periplasmic binding protein 53 310 5.5E-23 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain Mlab_1093 30ef804ec4b61b21b342a02e06a58ac9 376 Gene3D G3DSA:3.40.50.1980 30 176 4.1E-35 T 23-10-2018 Mlab_0159 ba66ccce7af0c272ddf0deb13dc23260 415 Gene3D G3DSA:2.40.50.1010 263 398 1.3E-40 T 23-10-2018 Mlab_0159 ba66ccce7af0c272ddf0deb13dc23260 415 Pfam PF08489 Domain of unknown function (DUF1743) 142 254 2.3E-33 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 Mlab_0159 ba66ccce7af0c272ddf0deb13dc23260 415 Gene3D G3DSA:3.30.70.2200 8 156 3.8E-45 T 23-10-2018 Mlab_0159 ba66ccce7af0c272ddf0deb13dc23260 415 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 10 415 33.677 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 Mlab_0159 ba66ccce7af0c272ddf0deb13dc23260 415 Gene3D G3DSA:3.90.600.20 158 253 1.2E-28 T 23-10-2018 Mlab_0032 b8e4c86165684fdb9b9c687fc92dec45 201 SMART SM01266 4 57 2.7E-10 T 23-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 Mlab_0032 b8e4c86165684fdb9b9c687fc92dec45 201 Pfam PF12464 Maltose acetyltransferase 7 56 1.5E-8 T 23-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 Mlab_0032 b8e4c86165684fdb9b9c687fc92dec45 201 Gene3D G3DSA:2.160.10.10 1 200 8.3E-58 T 23-10-2018 Mlab_0032 b8e4c86165684fdb9b9c687fc92dec45 201 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 139 172 6.2E-10 T 23-10-2018 IPR001451 Hexapeptide repeat Mlab_0032 b8e4c86165684fdb9b9c687fc92dec45 201 SUPERFAMILY SSF51161 4 196 1.04E-42 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily Mlab_0032 b8e4c86165684fdb9b9c687fc92dec45 201 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 146 174 - T 23-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Gene3D G3DSA:1.25.40.10 518 659 1.7E-23 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Gene3D G3DSA:1.25.40.10 660 792 2.8E-25 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Gene3D G3DSA:1.25.40.10 387 517 1.9E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SUPERFAMILY SSF48452 557 837 4.07E-38 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Pfam PF13181 Tetratricopeptide repeat 282 314 0.13 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Pfam PF13181 Tetratricopeptide repeat 318 341 0.065 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Pfam PF13181 Tetratricopeptide repeat 693 725 0.018 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 726 759 20.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 964 997 210.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 590 623 450.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 998 1031 0.026 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 213 246 55.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 82 115 240.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 522 555 13.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 316 349 170.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 453 486 150.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 760 793 160.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 692 725 0.13 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 657 691 26.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 14 47 0.19 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 896 929 5.4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 828 861 120.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 794 827 9.5 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 1032 1065 52.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 282 315 0.007 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 48 81 0.017 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SMART SM00028 556 589 0.03 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Pfam PF13414 TPR repeat 529 570 1.6E-9 T 23-10-2018 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Gene3D G3DSA:1.25.40.10 793 1069 1.7E-47 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Gene3D G3DSA:1.25.40.10 185 354 4.5E-18 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Gene3D G3DSA:1.25.40.10 119 184 3.2E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SUPERFAMILY SSF48452 459 554 6.83E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SUPERFAMILY SSF48452 893 1061 8.63E-29 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SUPERFAMILY SSF48452 17 173 3.79E-25 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Pfam PF13432 Tetratricopeptide repeat 466 509 0.013 T 23-10-2018 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Pfam PF13432 Tetratricopeptide repeat 731 791 0.0011 T 23-10-2018 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Pfam PF13432 Tetratricopeptide repeat 871 929 2.3E-6 T 23-10-2018 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Pfam PF13432 Tetratricopeptide repeat 1005 1059 7.6E-7 T 23-10-2018 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 SUPERFAMILY SSF48452 254 485 3.04E-21 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Gene3D G3DSA:1.25.40.10 10 118 6.3E-22 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Pfam PF14559 Tetratricopeptide repeat 25 88 2.2E-8 T 23-10-2018 Mlab_0678 f0a0d461ec7ee7b1051df3dcb05c7326 1073 Pfam PF14559 Tetratricopeptide repeat 125 177 1.1E-5 T 23-10-2018 Mlab_1648 acdadff1645f93f5255b01efce4afc36 351 SUPERFAMILY SSF48179 243 349 1.31E-16 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Mlab_1648 acdadff1645f93f5255b01efce4afc36 351 SUPERFAMILY SSF51735 92 235 1.32E-24 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1648 acdadff1645f93f5255b01efce4afc36 351 Pfam PF01817 Chorismate mutase type II 8 85 3.7E-12 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Mlab_1648 acdadff1645f93f5255b01efce4afc36 351 SUPERFAMILY SSF48600 3 85 1.83E-12 T 23-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Mlab_1648 acdadff1645f93f5255b01efce4afc36 351 Pfam PF02153 Prephenate dehydrogenase 127 315 1.2E-20 T 23-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 Mlab_1648 acdadff1645f93f5255b01efce4afc36 351 Gene3D G3DSA:3.40.50.720 81 248 2.1E-28 T 23-10-2018 Mlab_1648 acdadff1645f93f5255b01efce4afc36 351 Gene3D G3DSA:1.20.59.10 2 80 3.3E-11 T 23-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Mlab_1648 acdadff1645f93f5255b01efce4afc36 351 SMART SM00830 8 88 7.1E-12 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Mlab_1648 acdadff1645f93f5255b01efce4afc36 351 Gene3D G3DSA:1.10.3660.10 251 351 3.2E-5 T 23-10-2018 Mlab_0618 a29f65d3efb7d66918bd600a0bb86b7e 255 Gene3D G3DSA:3.30.70.20 176 232 3.3E-11 T 23-10-2018 Mlab_0618 a29f65d3efb7d66918bd600a0bb86b7e 255 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 213 224 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0618 a29f65d3efb7d66918bd600a0bb86b7e 255 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 181 192 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0618 a29f65d3efb7d66918bd600a0bb86b7e 255 Pfam PF12838 4Fe-4S dicluster domain 181 227 1.4E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0618 a29f65d3efb7d66918bd600a0bb86b7e 255 SUPERFAMILY SSF52218 2 106 1.73E-7 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0618 a29f65d3efb7d66918bd600a0bb86b7e 255 SUPERFAMILY SSF54862 178 248 1.74E-15 T 23-10-2018 Mlab_0355 383a8fb8cb4d72fec55518badbd7e8f2 222 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 4 222 31.175 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Mlab_0355 383a8fb8cb4d72fec55518badbd7e8f2 222 Gene3D G3DSA:3.30.70.260 129 205 1.5E-78 T 23-10-2018 Mlab_0355 383a8fb8cb4d72fec55518badbd7e8f2 222 SUPERFAMILY SSF100950 5 149 1.91E-40 T 23-10-2018 IPR037171 NagB/RpiA transferase-like Mlab_0355 383a8fb8cb4d72fec55518badbd7e8f2 222 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 8 216 1.0E-74 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Mlab_0355 383a8fb8cb4d72fec55518badbd7e8f2 222 SUPERFAMILY SSF75445 132 207 9.55E-23 T 23-10-2018 Mlab_0355 383a8fb8cb4d72fec55518badbd7e8f2 222 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 53 216 1.8E-61 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Mlab_0355 383a8fb8cb4d72fec55518badbd7e8f2 222 Gene3D G3DSA:3.40.50.1360 8 216 1.5E-78 T 23-10-2018 Mlab_0778 1ead8f7be3f54a86f4dcce521f0eac1c 445 Pfam PF01523 Putative modulator of DNA gyrase 6 295 9.8E-52 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 Mlab_0778 1ead8f7be3f54a86f4dcce521f0eac1c 445 PIRSF PIRSF004919 1 443 9.3E-116 T 23-10-2018 IPR025502 TldD Mlab_0778 1ead8f7be3f54a86f4dcce521f0eac1c 445 Gene3D G3DSA:3.30.2290.10 2 204 9.9E-10 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal Mlab_0778 1ead8f7be3f54a86f4dcce521f0eac1c 445 SUPERFAMILY SSF111283 4 441 1.02E-88 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 Gene3D G3DSA:3.20.20.70 4 487 3.6E-188 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 SMART SM01240 10 474 5.1E-266 T 23-10-2018 Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 Pfam PF00571 CBS domain 95 145 7.6E-10 T 23-10-2018 IPR000644 CBS domain Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 Pfam PF00571 CBS domain 154 208 2.7E-13 T 23-10-2018 IPR000644 CBS domain Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 SUPERFAMILY SSF51412 8 478 1.96E-107 T 23-10-2018 Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 11 455 4.1E-172 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 11 487 77.131 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 11 474 8.0E-145 T 23-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 294 306 - T 23-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 SUPERFAMILY SSF54631 92 206 1.04E-30 T 23-10-2018 Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 SMART SM00116 161 209 8.9E-8 T 23-10-2018 IPR000644 CBS domain Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 SMART SM00116 99 147 2.7E-11 T 23-10-2018 IPR000644 CBS domain Mlab_1382 99f0b6b75946d9688db971a9d1e969a4 489 PIRSF PIRSF000130 1 489 2.9E-189 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 TIGRFAM TIGR02090 LEU1_arch: isopropylmalate/citramalate/homocitrate synthases 10 368 2.9E-150 T 23-10-2018 IPR011830 Isopropylmalate/citramalate/homocitrate synthase GO:0019752|GO:0046912 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 17 33 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 Gene3D G3DSA:3.30.160.270 382 493 8.2E-9 T 23-10-2018 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 SUPERFAMILY SSF110921 383 491 8.89E-22 T 23-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 SMART SM00917 359 492 9.2E-33 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 193 206 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 Hamap MF_01028 Putative (R)-citramalate synthase CimA [cimA]. 17 492 71.614 T 23-10-2018 IPR024890 (R)-citramalate synthase CimA GO:0043714 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 SUPERFAMILY SSF51569 8 280 1.39E-85 T 23-10-2018 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 Pfam PF00682 HMGL-like 10 264 1.9E-74 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 Gene3D G3DSA:3.20.20.70 7 268 1.8E-87 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 Gene3D G3DSA:1.10.238.260 271 381 8.5E-34 T 23-10-2018 Mlab_0604 d43cde0b900c1fdfa456ad506f0529f2 504 Pfam PF08502 LeuA allosteric (dimerisation) domain 359 492 3.1E-30 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Mlab_0042 c4cc64b990ec811214a5e89f7041c2dc 318 Gene3D G3DSA:1.10.3720.10 80 317 1.0E-19 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0042 c4cc64b990ec811214a5e89f7041c2dc 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 313 2.4E-35 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_0042 c4cc64b990ec811214a5e89f7041c2dc 318 SUPERFAMILY SSF161098 91 296 5.1E-19 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0460 c3a84617f576d779b83284f4ac5a56e8 152 TIGRFAM TIGR01909 C_GCAxxG_C_C: C_GCAxxG_C_C family protein 15 142 3.3E-23 T 23-10-2018 IPR010181 CGCAxxGCC motif Mlab_0460 c3a84617f576d779b83284f4ac5a56e8 152 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 16 141 8.9E-30 T 23-10-2018 IPR010181 CGCAxxGCC motif Mlab_0967 52f11e199610e0e2e55fe9ebfa39657b 324 Pfam PF13439 Glycosyltransferase Family 4 42 134 1.0E-7 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Mlab_0967 52f11e199610e0e2e55fe9ebfa39657b 324 Gene3D G3DSA:3.40.50.2000 131 306 2.9E-43 T 23-10-2018 Mlab_0967 52f11e199610e0e2e55fe9ebfa39657b 324 Pfam PF00534 Glycosyl transferases group 1 146 279 2.4E-17 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 Mlab_0967 52f11e199610e0e2e55fe9ebfa39657b 324 SUPERFAMILY SSF53756 17 322 4.19E-52 T 23-10-2018 Mlab_0967 52f11e199610e0e2e55fe9ebfa39657b 324 Gene3D G3DSA:3.40.50.2000 42 319 2.9E-43 T 23-10-2018 Mlab_0640 38677bf2018774a20f95a644e6f5db42 292 SUPERFAMILY SSF46785 13 130 1.58E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0640 38677bf2018774a20f95a644e6f5db42 292 SMART SM00116 243 290 8.6E-8 T 23-10-2018 IPR000644 CBS domain Mlab_0640 38677bf2018774a20f95a644e6f5db42 292 SMART SM00116 180 227 5.8E-10 T 23-10-2018 IPR000644 CBS domain Mlab_0640 38677bf2018774a20f95a644e6f5db42 292 Gene3D G3DSA:3.10.580.10 231 290 5.2E-12 T 23-10-2018 Mlab_0640 38677bf2018774a20f95a644e6f5db42 292 PIRSF PIRSF005063 1 291 7.7E-100 T 23-10-2018 IPR016436 Uncharacterised conserved protein UCP005063, CBS-type Mlab_0640 38677bf2018774a20f95a644e6f5db42 292 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 2 78 2.4E-33 T 23-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 Mlab_0640 38677bf2018774a20f95a644e6f5db42 292 Gene3D G3DSA:3.10.580.10 105 230 2.2E-16 T 23-10-2018 Mlab_0640 38677bf2018774a20f95a644e6f5db42 292 SUPERFAMILY SSF54631 167 289 2.31E-29 T 23-10-2018 Mlab_0640 38677bf2018774a20f95a644e6f5db42 292 Pfam PF00571 CBS domain 236 288 1.3E-10 T 23-10-2018 IPR000644 CBS domain Mlab_0640 38677bf2018774a20f95a644e6f5db42 292 Pfam PF00571 CBS domain 173 227 1.2E-12 T 23-10-2018 IPR000644 CBS domain Mlab_0640 38677bf2018774a20f95a644e6f5db42 292 Gene3D G3DSA:1.10.10.10 10 86 1.6E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1296 d7d5baf7cbe94b0f3c2c728f5ad556cf 373 SUPERFAMILY SSF89550 3 226 4.12E-18 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Mlab_1296 d7d5baf7cbe94b0f3c2c728f5ad556cf 373 Pfam PF13263 PHP-associated 180 222 2.2E-6 T 23-10-2018 Mlab_1296 d7d5baf7cbe94b0f3c2c728f5ad556cf 373 Gene3D G3DSA:3.20.20.140 4 227 2.2E-16 T 23-10-2018 Mlab_1230 062821eee5242f5fa2016f91871b711d 571 ProSitePatterns PS00455 Putative AMP-binding domain signature. 218 229 - T 23-10-2018 IPR020845 AMP-binding, conserved site Mlab_1230 062821eee5242f5fa2016f91871b711d 571 SUPERFAMILY SSF56801 32 570 4.45E-117 T 23-10-2018 Mlab_1230 062821eee5242f5fa2016f91871b711d 571 Gene3D G3DSA:3.40.50.12780 21 471 3.4E-92 T 23-10-2018 Mlab_1230 062821eee5242f5fa2016f91871b711d 571 Gene3D G3DSA:3.30.300.30 472 571 2.5E-17 T 23-10-2018 Mlab_1230 062821eee5242f5fa2016f91871b711d 571 Pfam PF13193 AMP-binding enzyme C-terminal domain 486 560 9.1E-7 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Mlab_1230 062821eee5242f5fa2016f91871b711d 571 Pfam PF00501 AMP-binding enzyme 46 476 3.5E-87 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Mlab_0629 ec3529e450d2134f35dea11314935afa 550 SMART SM00155 457 484 5.2E-6 T 23-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 Mlab_0629 ec3529e450d2134f35dea11314935afa 550 SMART SM00155 264 291 48.0 T 23-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 Mlab_0629 ec3529e450d2134f35dea11314935afa 550 Pfam PF13091 PLD-like domain 375 512 3.1E-23 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Mlab_0629 ec3529e450d2134f35dea11314935afa 550 Pfam PF13091 PLD-like domain 186 322 1.7E-14 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Mlab_0629 ec3529e450d2134f35dea11314935afa 550 SUPERFAMILY SSF56024 361 520 4.26E-29 T 23-10-2018 Mlab_0629 ec3529e450d2134f35dea11314935afa 550 Gene3D G3DSA:3.30.870.10 356 514 2.0E-28 T 23-10-2018 Mlab_0629 ec3529e450d2134f35dea11314935afa 550 Gene3D G3DSA:3.30.870.10 152 325 9.9E-26 T 23-10-2018 Mlab_0629 ec3529e450d2134f35dea11314935afa 550 SUPERFAMILY SSF56024 164 324 6.06E-22 T 23-10-2018 Mlab_1255 b72d665e351b549177eeaca5fc546779 319 Pfam PF04055 Radical SAM superfamily 26 187 3.1E-31 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_1255 b72d665e351b549177eeaca5fc546779 319 Pfam PF13353 4Fe-4S single cluster domain 27 131 6.8E-8 T 23-10-2018 Mlab_1255 b72d665e351b549177eeaca5fc546779 319 SMART SM00729 20 227 4.6E-7 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_1255 b72d665e351b549177eeaca5fc546779 319 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 11 317 38.813 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 Mlab_1255 b72d665e351b549177eeaca5fc546779 319 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 26 37 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1255 b72d665e351b549177eeaca5fc546779 319 SUPERFAMILY SSF102114 12 296 4.58E-68 T 23-10-2018 Mlab_1255 b72d665e351b549177eeaca5fc546779 319 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 11 316 2.4E-106 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 Mlab_1255 b72d665e351b549177eeaca5fc546779 319 Pfam PF06463 Molybdenum Cofactor Synthesis C 196 316 1.6E-21 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1255 b72d665e351b549177eeaca5fc546779 319 Gene3D G3DSA:3.20.20.70 8 316 1.5E-75 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1249 58b19fb253ee484f882137a6b355e164 204 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 4 135 4.6E-45 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 Mlab_1249 58b19fb253ee484f882137a6b355e164 204 Pfam PF01938 TRAM domain 148 200 1.1E-9 T 23-10-2018 IPR002792 TRAM domain Mlab_1249 58b19fb253ee484f882137a6b355e164 204 Pfam PF01873 Domain found in IF2B/IF5 21 130 1.6E-38 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 Mlab_1249 58b19fb253ee484f882137a6b355e164 204 Gene3D G3DSA:2.40.50.140 137 204 3.2E-19 T 23-10-2018 Mlab_1249 58b19fb253ee484f882137a6b355e164 204 SUPERFAMILY SSF75689 100 134 4.58E-11 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 Mlab_1249 58b19fb253ee484f882137a6b355e164 204 SMART SM00653 23 130 3.0E-51 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 Mlab_1249 58b19fb253ee484f882137a6b355e164 204 SUPERFAMILY SSF100966 4 103 5.1E-27 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 Mlab_1249 58b19fb253ee484f882137a6b355e164 204 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 3 136 32.011 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 Mlab_1249 58b19fb253ee484f882137a6b355e164 204 Gene3D G3DSA:3.30.70.3150 34 124 3.2E-31 T 23-10-2018 Mlab_1249 58b19fb253ee484f882137a6b355e164 204 SUPERFAMILY SSF50249 143 200 2.4E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0964 5ed13b96b713b4af6243b086b82df70d 543 Gene3D G3DSA:3.40.50.300 5 223 3.2E-52 T 23-10-2018 Mlab_0964 5ed13b96b713b4af6243b086b82df70d 543 Pfam PF07728 AAA domain (dynein-related subfamily) 45 173 1.2E-21 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Mlab_0964 5ed13b96b713b4af6243b086b82df70d 543 Gene3D G3DSA:1.10.8.300 224 292 5.3E-23 T 23-10-2018 Mlab_0964 5ed13b96b713b4af6243b086b82df70d 543 SUPERFAMILY SSF52540 26 265 1.01E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0964 5ed13b96b713b4af6243b086b82df70d 543 SMART SM00382 41 183 6.4E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0137 7506dc78be8592aac31dfd6dc9cbfbed 577 Pfam PF02436 Conserved carboxylase domain 292 481 3.1E-53 T 23-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 Mlab_0137 7506dc78be8592aac31dfd6dc9cbfbed 577 SUPERFAMILY SSF89000 297 456 8.63E-49 T 23-10-2018 Mlab_0137 7506dc78be8592aac31dfd6dc9cbfbed 577 Pfam PF00364 Biotin-requiring enzyme 515 575 1.3E-16 T 23-10-2018 IPR000089 Biotin/lipoyl attachment Mlab_0137 7506dc78be8592aac31dfd6dc9cbfbed 577 Gene3D G3DSA:3.20.20.70 1 457 1.7E-160 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0137 7506dc78be8592aac31dfd6dc9cbfbed 577 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 533 550 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Mlab_0137 7506dc78be8592aac31dfd6dc9cbfbed 577 SUPERFAMILY SSF51569 1 285 6.23E-84 T 23-10-2018 Mlab_0137 7506dc78be8592aac31dfd6dc9cbfbed 577 SUPERFAMILY SSF51230 506 576 1.83E-20 T 23-10-2018 IPR011053 Single hybrid motif Mlab_0137 7506dc78be8592aac31dfd6dc9cbfbed 577 Pfam PF00682 HMGL-like 4 267 2.8E-42 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Mlab_0137 7506dc78be8592aac31dfd6dc9cbfbed 577 Gene3D G3DSA:2.40.50.100 506 576 1.2E-21 T 23-10-2018 Mlab_0407 7d57875155b5eeb63bc43ca963096b61 107 Gene3D G3DSA:3.40.140.10 1 107 1.1E-22 T 23-10-2018 Mlab_0407 7d57875155b5eeb63bc43ca963096b61 107 Pfam PF14464 Prokaryotic homologs of the JAB domain 13 93 2.6E-9 T 23-10-2018 IPR028090 JAB domain, prokaryotic Mlab_0407 7d57875155b5eeb63bc43ca963096b61 107 SUPERFAMILY SSF102712 2 105 2.22E-22 T 23-10-2018 Mlab_0150 c93d414263630b16be6b98ff8a508b11 462 Gene3D G3DSA:3.40.50.2020 263 426 3.9E-129 T 23-10-2018 Mlab_0150 c93d414263630b16be6b98ff8a508b11 462 PIRSF PIRSF000485 1 455 2.4E-144 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Mlab_0150 c93d414263630b16be6b98ff8a508b11 462 Gene3D G3DSA:3.60.20.10 3 444 3.9E-129 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Mlab_0150 c93d414263630b16be6b98ff8a508b11 462 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 443 39.828 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Mlab_0150 c93d414263630b16be6b98ff8a508b11 462 SUPERFAMILY SSF56235 3 245 5.06E-46 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Mlab_0150 c93d414263630b16be6b98ff8a508b11 462 SUPERFAMILY SSF53271 239 450 1.13E-61 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like Mlab_0150 c93d414263630b16be6b98ff8a508b11 462 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 3 444 6.4E-134 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Mlab_0150 c93d414263630b16be6b98ff8a508b11 462 Pfam PF00156 Phosphoribosyl transferase domain 261 372 3.4E-8 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Mlab_0150 c93d414263630b16be6b98ff8a508b11 462 Pfam PF13537 Glutamine amidotransferase domain 83 201 1.2E-13 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain Mlab_0484 021e808c97480837c2ae651a11d03797 377 SUPERFAMILY SSF52518 5 253 3.19E-71 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_0484 021e808c97480837c2ae651a11d03797 377 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 247 5.4E-73 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Mlab_0484 021e808c97480837c2ae651a11d03797 377 Gene3D G3DSA:3.40.50.970 2 192 3.8E-77 T 23-10-2018 Mlab_0484 021e808c97480837c2ae651a11d03797 377 SUPERFAMILY SSF52922 267 365 6.28E-13 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Mlab_0484 021e808c97480837c2ae651a11d03797 377 Gene3D G3DSA:3.40.50.920 265 365 1.7E-14 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Mlab_0484 021e808c97480837c2ae651a11d03797 377 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 270 357 4.3E-11 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II Mlab_0191 98c38eea8893513331e703b5c94ae252 162 PRINTS PR01576 Peptide deformylase signature 96 114 3.5E-32 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0191 98c38eea8893513331e703b5c94ae252 162 PRINTS PR01576 Peptide deformylase signature 84 95 3.5E-32 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0191 98c38eea8893513331e703b5c94ae252 162 PRINTS PR01576 Peptide deformylase signature 115 144 3.5E-32 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0191 98c38eea8893513331e703b5c94ae252 162 PRINTS PR01576 Peptide deformylase signature 30 59 3.5E-32 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0191 98c38eea8893513331e703b5c94ae252 162 Gene3D G3DSA:3.90.45.10 1 162 5.5E-55 T 23-10-2018 IPR036821 Peptide deformylase superfamily Mlab_0191 98c38eea8893513331e703b5c94ae252 162 Pfam PF01327 Polypeptide deformylase 2 146 2.8E-46 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0191 98c38eea8893513331e703b5c94ae252 162 SUPERFAMILY SSF56420 2 157 5.63E-53 T 23-10-2018 IPR036821 Peptide deformylase superfamily Mlab_0191 98c38eea8893513331e703b5c94ae252 162 Hamap MF_00163 Peptide deformylase [def]. 1 157 25.945 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0191 98c38eea8893513331e703b5c94ae252 162 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 2 154 1.1E-41 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0191 98c38eea8893513331e703b5c94ae252 162 PIRSF PIRSF004749 1 162 5.5E-50 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0887 b217fc981ba8b193e3052a12b839086d 232 SUPERFAMILY SSF52540 1 145 6.14E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0887 b217fc981ba8b193e3052a12b839086d 232 Gene3D G3DSA:3.40.50.300 3 195 4.4E-25 T 23-10-2018 Mlab_0887 b217fc981ba8b193e3052a12b839086d 232 Pfam PF13671 AAA domain 6 141 2.6E-7 T 23-10-2018 Mlab_0305 257cff797676f42f2b653b2967b609f6 571 SUPERFAMILY SSF54001 15 292 6.78E-31 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Mlab_0305 257cff797676f42f2b653b2967b609f6 571 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 44 55 - T 23-10-2018 IPR000169 Cysteine peptidase, cysteine active site Mlab_1435 6573520be1dab696f9e1a4be9b5447c0 255 SUPERFAMILY SSF161098 38 225 2.62E-42 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1435 6573520be1dab696f9e1a4be9b5447c0 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 58 239 9.1E-18 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_1435 6573520be1dab696f9e1a4be9b5447c0 255 Gene3D G3DSA:1.10.3720.10 34 240 8.9E-52 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1435 6573520be1dab696f9e1a4be9b5447c0 255 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 37 134 2.9E-29 T 23-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 Mlab_0323 5dc6a5e8e48279e4891fca49a1bd6aaf 496 TIGRFAM TIGR03285 methan_mark_14: putative methanogenesis marker protein 14 41 494 3.8E-182 T 23-10-2018 IPR008303 Putative methanogenesis marker protein 14 Mlab_0323 5dc6a5e8e48279e4891fca49a1bd6aaf 496 PIRSF PIRSF016937 10 496 2.4E-195 T 23-10-2018 IPR008303 Putative methanogenesis marker protein 14 Mlab_0323 5dc6a5e8e48279e4891fca49a1bd6aaf 496 Pfam PF09887 Uncharacterized protein conserved in archaea (DUF2114) 40 494 1.8E-223 T 23-10-2018 IPR008303 Putative methanogenesis marker protein 14 Mlab_0793 e13c419dd2334c78bb811ac270a49a9b 155 SUPERFAMILY SSF57825 105 148 2.62E-14 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily Mlab_0793 e13c419dd2334c78bb811ac270a49a9b 155 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 11 100 3.5E-29 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal Mlab_0793 e13c419dd2334c78bb811ac270a49a9b 155 SUPERFAMILY SSF54893 7 103 3.27E-30 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily Mlab_0793 e13c419dd2334c78bb811ac270a49a9b 155 Gene3D G3DSA:3.30.70.140 1 102 3.3E-32 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily Mlab_0793 e13c419dd2334c78bb811ac270a49a9b 155 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 11 92 5.0E-22 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal Mlab_0793 e13c419dd2334c78bb811ac270a49a9b 155 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 105 146 4.2E-14 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal Mlab_0793 e13c419dd2334c78bb811ac270a49a9b 155 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 9 146 1.2E-50 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 Mlab_0793 e13c419dd2334c78bb811ac270a49a9b 155 Gene3D G3DSA:2.30.30.20 103 149 1.6E-13 T 23-10-2018 Mlab_0793 e13c419dd2334c78bb811ac270a49a9b 155 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 6 152 30.387 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 Mlab_1409 f7a68715fbadbdb43815eaebf7ff723a 282 Gene3D G3DSA:3.40.1090.10 2 63 3.7E-10 T 23-10-2018 Mlab_1409 f7a68715fbadbdb43815eaebf7ff723a 282 Gene3D G3DSA:3.40.1090.10 83 231 9.3E-14 T 23-10-2018 Mlab_1409 f7a68715fbadbdb43815eaebf7ff723a 282 Pfam PF01734 Patatin-like phospholipase 6 169 1.6E-20 T 23-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Mlab_1409 f7a68715fbadbdb43815eaebf7ff723a 282 SUPERFAMILY SSF52151 5 271 1.44E-43 T 23-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Mlab_1556 4514f7f0d283daac63b5d7a312091d13 245 PIRSF PIRSF009452 1 241 2.2E-90 T 23-10-2018 IPR030688 Methyltransferase MtrA/MtxA KEGG: 00680+2.1.1.86 Mlab_1556 4514f7f0d283daac63b5d7a312091d13 245 Hamap MF_01093 Tetrahydromethanopterin S-methyltransferase subunit A [mtrA]. 1 181 40.114 T 23-10-2018 IPR005778 Tetrahydromethanopterin S-methyltransferase subunit A, MtrA GO:0006814|GO:0030269|GO:0050897 KEGG: 00680+2.1.1.86 Mlab_1556 4514f7f0d283daac63b5d7a312091d13 245 PIRSF PIRSF500207 1 241 4.2E-91 T 23-10-2018 IPR005778 Tetrahydromethanopterin S-methyltransferase subunit A, MtrA GO:0006814|GO:0030269|GO:0050897 KEGG: 00680+2.1.1.86 Mlab_1556 4514f7f0d283daac63b5d7a312091d13 245 TIGRFAM TIGR01111 mtrA: tetrahydromethanopterin S-methyltransferase, subunit A 1 239 1.3E-96 T 23-10-2018 IPR005778 Tetrahydromethanopterin S-methyltransferase subunit A, MtrA GO:0006814|GO:0030269|GO:0050897 KEGG: 00680+2.1.1.86 Mlab_1556 4514f7f0d283daac63b5d7a312091d13 245 Pfam PF04208 Tetrahydromethanopterin S-methyltransferase, subunit A 4 172 2.1E-81 T 23-10-2018 IPR030688 Methyltransferase MtrA/MtxA KEGG: 00680+2.1.1.86 Mlab_0843 a9045aff75852798a5269d4e7ab9acef 983 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 113 208 1.7E-16 T 23-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 Mlab_0843 a9045aff75852798a5269d4e7ab9acef 983 SMART SM00487 270 491 1.8E-12 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Mlab_0843 a9045aff75852798a5269d4e7ab9acef 983 SUPERFAMILY SSF52540 235 475 1.68E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0843 a9045aff75852798a5269d4e7ab9acef 983 Gene3D G3DSA:3.90.1570.50 102 261 9.2E-10 T 23-10-2018 Mlab_0843 a9045aff75852798a5269d4e7ab9acef 983 SUPERFAMILY SSF52540 295 713 3.54E-6 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0843 a9045aff75852798a5269d4e7ab9acef 983 Gene3D G3DSA:3.40.50.300 491 724 1.8E-22 T 23-10-2018 Mlab_0843 a9045aff75852798a5269d4e7ab9acef 983 Gene3D G3DSA:3.40.50.300 270 432 2.2E-26 T 23-10-2018 Mlab_0843 a9045aff75852798a5269d4e7ab9acef 983 Pfam PF04851 Type III restriction enzyme, res subunit 274 466 1.5E-15 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Mlab_0769 5192d069a79c321128c8dd92ab5c0925 144 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 137 1.6E-14 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Mlab_0769 5192d069a79c321128c8dd92ab5c0925 144 SUPERFAMILY SSF54534 4 141 2.86E-32 T 23-10-2018 Mlab_0769 5192d069a79c321128c8dd92ab5c0925 144 Gene3D G3DSA:3.10.50.40 2 144 4.6E-38 T 23-10-2018 Mlab_0902 3b3dbe914df7a1e31ae1424254c5907b 465 Gene3D G3DSA:3.50.50.60 2 463 4.6E-85 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0902 3b3dbe914df7a1e31ae1424254c5907b 465 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 5.5E-6 T 23-10-2018 Mlab_0902 3b3dbe914df7a1e31ae1424254c5907b 465 PRINTS PR00419 Adrenodoxin reductase family signature 29 42 5.5E-6 T 23-10-2018 Mlab_0902 3b3dbe914df7a1e31ae1424254c5907b 465 SUPERFAMILY SSF51905 1 458 2.07E-29 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0902 3b3dbe914df7a1e31ae1424254c5907b 465 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 63 1.0E-13 T 23-10-2018 Mlab_0154 0e780a7c5ce5f26c60dc21ba063f3757 312 Pfam PF01916 Deoxyhypusine synthase 22 305 5.1E-94 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 Mlab_0154 0e780a7c5ce5f26c60dc21ba063f3757 312 SUPERFAMILY SSF52467 4 310 4.58E-97 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Mlab_0154 0e780a7c5ce5f26c60dc21ba063f3757 312 Gene3D G3DSA:3.40.910.10 2 312 4.1E-90 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 Pfam PF01624 MutS domain I 8 120 2.5E-40 T 23-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 7 853 23.534 T 23-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 Gene3D G3DSA:3.40.1170.10 1 122 1.1E-45 T 23-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 SUPERFAMILY SSF52540 573 803 1.54E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 Gene3D G3DSA:1.10.1420.10 394 509 3.9E-95 T 23-10-2018 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 SMART SM00533 290 597 1.9E-92 T 23-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 Pfam PF05188 MutS domain II 130 259 2.6E-21 T 23-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 Gene3D G3DSA:3.40.50.300 574 862 4.7E-99 T 23-10-2018 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 SUPERFAMILY SSF55271 4 116 1.44E-41 T 23-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 Gene3D G3DSA:1.10.1420.10 272 565 3.9E-95 T 23-10-2018 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 Gene3D G3DSA:3.30.420.110 129 265 3.6E-24 T 23-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 695 711 - T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 Pfam PF05192 MutS domain III 276 565 4.4E-41 T 23-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 7 858 4.6E-277 T 23-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 SUPERFAMILY SSF53150 118 285 9.94E-29 T 23-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 Pfam PF00488 MutS domain V 617 803 2.0E-79 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 Pfam PF05190 MutS family domain IV 434 524 2.0E-27 T 23-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 SUPERFAMILY SSF48334 273 570 9.02E-85 T 23-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 SMART SM00534 614 803 4.2E-111 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Mlab_1169 acb1e413bbce85ab29ae2fcb56769f73 864 PIRSF PIRSF037677 3 829 6.5E-165 T 23-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 Mlab_0459 c836c9fbd373a79e4bb7f0419297afe2 159 Pfam PF01966 HD domain 18 120 6.0E-15 T 23-10-2018 IPR006674 HD domain Mlab_0459 c836c9fbd373a79e4bb7f0419297afe2 159 SUPERFAMILY SSF109604 16 121 2.43E-16 T 23-10-2018 Mlab_0459 c836c9fbd373a79e4bb7f0419297afe2 159 TIGRFAM TIGR00277 HDIG: HDIG domain 14 86 2.0E-17 T 23-10-2018 IPR006675 HDIG domain Mlab_0459 c836c9fbd373a79e4bb7f0419297afe2 159 SMART SM00471 13 132 1.3E-8 T 23-10-2018 IPR003607 HD/PDEase domain Mlab_0459 c836c9fbd373a79e4bb7f0419297afe2 159 Gene3D G3DSA:1.10.3210.10 3 146 7.6E-16 T 23-10-2018 Mlab_0204 d46dede7c3d7bee8dfc5d3213763321a 736 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 10 554 5.7E-194 T 23-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Mlab_0204 d46dede7c3d7bee8dfc5d3213763321a 736 SUPERFAMILY SSF48168 27 68 1.62E-5 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Mlab_0204 d46dede7c3d7bee8dfc5d3213763321a 736 PRINTS PR01183 Ribonucleotide reductase large chain signature 145 164 9.0E-28 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Mlab_0204 d46dede7c3d7bee8dfc5d3213763321a 736 PRINTS PR01183 Ribonucleotide reductase large chain signature 386 413 9.0E-28 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Mlab_0204 d46dede7c3d7bee8dfc5d3213763321a 736 PRINTS PR01183 Ribonucleotide reductase large chain signature 318 340 9.0E-28 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Mlab_0204 d46dede7c3d7bee8dfc5d3213763321a 736 PRINTS PR01183 Ribonucleotide reductase large chain signature 346 369 9.0E-28 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Mlab_0204 d46dede7c3d7bee8dfc5d3213763321a 736 PRINTS PR01183 Ribonucleotide reductase large chain signature 280 303 9.0E-28 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Mlab_0204 d46dede7c3d7bee8dfc5d3213763321a 736 Pfam PF02867 Ribonucleotide reductase, barrel domain 70 544 2.9E-144 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Mlab_0204 d46dede7c3d7bee8dfc5d3213763321a 736 SUPERFAMILY SSF51998 69 553 5.49E-144 T 23-10-2018 Mlab_0204 d46dede7c3d7bee8dfc5d3213763321a 736 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 9 67 1.9E-13 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Mlab_0204 d46dede7c3d7bee8dfc5d3213763321a 736 Gene3D G3DSA:3.20.70.20 3 559 3.3E-202 T 23-10-2018 Mlab_1466 6406b64bff94e8112756613cf1b381d5 182 Pfam PF07790 Archaeal Type IV pilin, N-terminal 53 118 1.4E-11 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_1466 6406b64bff94e8112756613cf1b381d5 182 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 54 75 1.9E-4 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal Mlab_0817 02442aea75d9e4bcad7be64c5ab76f7b 132 SMART SM00418 54 131 2.2E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0817 02442aea75d9e4bcad7be64c5ab76f7b 132 Gene3D G3DSA:1.10.10.10 18 127 9.9E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0817 02442aea75d9e4bcad7be64c5ab76f7b 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 88 103 5.3E-15 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0817 02442aea75d9e4bcad7be64c5ab76f7b 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 86 5.3E-15 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0817 02442aea75d9e4bcad7be64c5ab76f7b 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 5.3E-15 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0817 02442aea75d9e4bcad7be64c5ab76f7b 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 103 118 5.3E-15 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0817 02442aea75d9e4bcad7be64c5ab76f7b 132 SUPERFAMILY SSF46785 49 126 9.49E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0817 02442aea75d9e4bcad7be64c5ab76f7b 132 Pfam PF01022 Bacterial regulatory protein, arsR family 61 106 1.2E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_1011 66599a46b9de861138bc748b0d87cf2d 253 Pfam PF02616 Segregation and condensation protein ScpA 20 245 1.1E-12 T 23-10-2018 IPR003768 Segregation and condensation protein A Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 Gene3D G3DSA:3.10.580.10 2 127 2.3E-14 T 23-10-2018 Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 SMART SM00116 138 185 0.012 T 23-10-2018 IPR000644 CBS domain Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 SMART SM00116 81 127 7.9 T 23-10-2018 IPR000644 CBS domain Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 SMART SM00116 13 60 3.0 T 23-10-2018 IPR000644 CBS domain Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 SMART SM00116 211 257 3.2E-4 T 23-10-2018 IPR000644 CBS domain Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 Gene3D G3DSA:3.10.580.10 133 257 6.1E-25 T 23-10-2018 Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 Pfam PF00571 CBS domain 77 126 0.001 T 23-10-2018 IPR000644 CBS domain Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 Pfam PF00571 CBS domain 7 58 0.0013 T 23-10-2018 IPR000644 CBS domain Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 Pfam PF00571 CBS domain 141 185 4.1E-7 T 23-10-2018 IPR000644 CBS domain Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 Pfam PF00571 CBS domain 204 257 2.7E-10 T 23-10-2018 IPR000644 CBS domain Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 SUPERFAMILY SSF54631 142 257 1.52E-23 T 23-10-2018 Mlab_0749 dc1761029365d1be5fcbf9e22c52e297 257 SUPERFAMILY SSF54631 5 127 3.54E-17 T 23-10-2018 Mlab_0481 8569af31d696adc468d7ca76118133ff 328 Pfam PF00742 Homoserine dehydrogenase 145 320 1.7E-54 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 Mlab_0481 8569af31d696adc468d7ca76118133ff 328 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 191 213 - T 23-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 Mlab_0481 8569af31d696adc468d7ca76118133ff 328 Gene3D G3DSA:3.30.360.10 156 303 7.3E-96 T 23-10-2018 Mlab_0481 8569af31d696adc468d7ca76118133ff 328 PIRSF PIRSF036497 1 328 1.6E-99 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 Mlab_0481 8569af31d696adc468d7ca76118133ff 328 SUPERFAMILY SSF55347 145 307 2.22E-46 T 23-10-2018 Mlab_0481 8569af31d696adc468d7ca76118133ff 328 SUPERFAMILY SSF51735 1 166 8.62E-29 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0481 8569af31d696adc468d7ca76118133ff 328 Gene3D G3DSA:3.40.50.720 6 320 7.3E-96 T 23-10-2018 Mlab_0481 8569af31d696adc468d7ca76118133ff 328 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 137 1.8E-8 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 Gene3D G3DSA:2.170.190.11 49 145 1.0E-96 T 23-10-2018 Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 181 310 2.8E-29 T 23-10-2018 IPR001453 MoaB/Mog domain Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 1.9E-37 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 Gene3D G3DSA:3.40.980.10 179 320 1.0E-96 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 Pfam PF00994 Probable molybdopterin binding domain 184 319 2.8E-23 T 23-10-2018 IPR001453 MoaB/Mog domain Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 SUPERFAMILY SSF63867 331 400 1.57E-17 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 Gene3D G3DSA:3.90.105.10 26 178 1.0E-96 T 23-10-2018 Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 SMART SM00852 184 321 1.8E-34 T 23-10-2018 IPR001453 MoaB/Mog domain Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 Gene3D G3DSA:2.40.340.10 331 400 2.3E-21 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 Pfam PF03454 MoeA C-terminal region (domain IV) 333 399 6.5E-16 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 SUPERFAMILY SSF63882 6 180 5.89E-50 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1505 8925a7b4c4aef6a038828d450132c158 400 SUPERFAMILY SSF53218 181 323 1.83E-39 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily Mlab_0626 aae75bb8e59ad099ec5965b40f4a65ca 86 Pfam PF00736 EF-1 guanine nucleotide exchange domain 6 85 2.8E-18 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 Mlab_0626 aae75bb8e59ad099ec5965b40f4a65ca 86 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 1 85 2.3E-20 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 Mlab_0626 aae75bb8e59ad099ec5965b40f4a65ca 86 Gene3D G3DSA:3.30.70.60 1 86 1.3E-26 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 Mlab_0626 aae75bb8e59ad099ec5965b40f4a65ca 86 SUPERFAMILY SSF54984 1 85 4.32E-21 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 Mlab_0626 aae75bb8e59ad099ec5965b40f4a65ca 86 SMART SM00888 3 85 5.6E-33 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 Mlab_0626 aae75bb8e59ad099ec5965b40f4a65ca 86 PIRSF PIRSF006521 1 85 5.5E-26 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 Mlab_0626 aae75bb8e59ad099ec5965b40f4a65ca 86 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 86 34.347 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 Mlab_0691 54df2a9861f1ec328fc0a2627a484b9c 564 Gene3D G3DSA:3.30.450.20 304 432 4.9E-27 T 23-10-2018 Mlab_0691 54df2a9861f1ec328fc0a2627a484b9c 564 Gene3D G3DSA:3.30.450.20 433 553 2.9E-9 T 23-10-2018 Mlab_0691 54df2a9861f1ec328fc0a2627a484b9c 564 Pfam PF17200 Single Cache domain 2 316 424 1.1E-15 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0691 54df2a9861f1ec328fc0a2627a484b9c 564 SMART SM01049 294 376 5.3E-7 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0691 54df2a9861f1ec328fc0a2627a484b9c 564 SMART SM01049 440 516 1.0 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_1104 e7d6faa8ca3d620b5344e6ad82f5f773 676 Pfam PF13307 Helicase C-terminal domain 487 651 3.6E-33 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Mlab_1104 e7d6faa8ca3d620b5344e6ad82f5f773 676 Gene3D G3DSA:3.40.50.300 453 644 1.9E-43 T 23-10-2018 Mlab_1104 e7d6faa8ca3d620b5344e6ad82f5f773 676 SUPERFAMILY SSF52540 9 266 1.44E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1104 e7d6faa8ca3d620b5344e6ad82f5f773 676 SMART SM00491 504 638 3.8E-26 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Mlab_1104 e7d6faa8ca3d620b5344e6ad82f5f773 676 Pfam PF06777 Helical and beta-bridge domain 338 467 5.5E-10 T 23-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 Mlab_1104 e7d6faa8ca3d620b5344e6ad82f5f773 676 Pfam PF06733 DEAD_2 63 273 1.9E-15 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 Mlab_1104 e7d6faa8ca3d620b5344e6ad82f5f773 676 SMART SM00488 4 295 6.5E-6 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 Gene3D G3DSA:3.10.580.10 131 284 2.9E-23 T 23-10-2018 Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 Pfam PF00571 CBS domain 232 283 1.2E-6 T 23-10-2018 IPR000644 CBS domain Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 Pfam PF00571 CBS domain 141 181 8.2E-5 T 23-10-2018 IPR000644 CBS domain Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 Pfam PF00571 CBS domain 69 120 2.0E-14 T 23-10-2018 IPR000644 CBS domain Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 Pfam PF00571 CBS domain 6 60 3.2E-12 T 23-10-2018 IPR000644 CBS domain Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 SMART SM00116 235 283 2.4E-5 T 23-10-2018 IPR000644 CBS domain Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 SMART SM00116 13 62 1.1E-8 T 23-10-2018 IPR000644 CBS domain Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 SMART SM00116 136 184 7.4 T 23-10-2018 IPR000644 CBS domain Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 SMART SM00116 73 120 1.1E-12 T 23-10-2018 IPR000644 CBS domain Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 SUPERFAMILY SSF54631 2 121 5.56E-33 T 23-10-2018 Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 Gene3D G3DSA:3.10.580.10 2 130 5.5E-30 T 23-10-2018 Mlab_0310 0ed5bc68df1cb490edd2bce3396076df 284 SUPERFAMILY SSF54631 135 282 5.31E-21 T 23-10-2018 Mlab_0182 2b4d77cf5d76ff179cdd445f1dd83f2f 529 Pfam PF00860 Permease family 24 394 7.5E-46 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 Mlab_0552 da0fa9a508d955ce38765dc7d352a5b3 148 Pfam PF09885 Uncharacterized protein conserved in archaea (DUF2112) 2 144 1.6E-63 T 23-10-2018 IPR012356 Uncharacterised conserved protein UCP018781, methanogenesis Mlab_0552 da0fa9a508d955ce38765dc7d352a5b3 148 PIRSF PIRSF018781 1 148 3.4E-67 T 23-10-2018 IPR012356 Uncharacterised conserved protein UCP018781, methanogenesis Mlab_0552 da0fa9a508d955ce38765dc7d352a5b3 148 TIGRFAM TIGR03271 methan_mark_5: putative methanogenesis marker protein 5 3 144 6.3E-68 T 23-10-2018 IPR012356 Uncharacterised conserved protein UCP018781, methanogenesis Mlab_1067 51dae246e750c1ed85e99b33ea2e72c2 254 Pfam PF02240 Methyl-coenzyme M reductase gamma subunit 5 250 3.2E-125 T 23-10-2018 IPR003178 Methyl-coenzyme M reductase, gamma subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1067 51dae246e750c1ed85e99b33ea2e72c2 254 SUPERFAMILY SSF55088 6 252 1.22E-117 T 23-10-2018 IPR009024 Methyl-coenzyme M reductase, ferredoxin-like fold GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1067 51dae246e750c1ed85e99b33ea2e72c2 254 ProDom PD005845 GAMMA SUBUNIT M REDUCTASE METHYL COENZYME METHYL-COENZYME TRANSFERASE SULFOETHYLTHIOTRANSFERASE COENZYME-B 10 251 5.0E-116 T 23-10-2018 IPR003178 Methyl-coenzyme M reductase, gamma subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1067 51dae246e750c1ed85e99b33ea2e72c2 254 Gene3D G3DSA:3.90.320.20 1 254 3.5E-114 T 23-10-2018 IPR036994 Methyl-coenzyme M reductase, gamma subunit superfamily GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1067 51dae246e750c1ed85e99b33ea2e72c2 254 TIGRFAM TIGR03259 met_CoM_red_gam: methyl-coenzyme M reductase, gamma subunit 6 249 6.0E-105 T 23-10-2018 IPR003178 Methyl-coenzyme M reductase, gamma subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1232 cea20d780893229544fbc1b8309da535 568 Pfam PF13193 AMP-binding enzyme C-terminal domain 469 544 1.1E-6 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Mlab_1232 cea20d780893229544fbc1b8309da535 568 ProSitePatterns PS00455 Putative AMP-binding domain signature. 201 212 - T 23-10-2018 IPR020845 AMP-binding, conserved site Mlab_1232 cea20d780893229544fbc1b8309da535 568 Gene3D G3DSA:3.30.300.30 455 564 4.5E-15 T 23-10-2018 Mlab_1232 cea20d780893229544fbc1b8309da535 568 Pfam PF00501 AMP-binding enzyme 30 459 4.5E-85 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Mlab_1232 cea20d780893229544fbc1b8309da535 568 SUPERFAMILY SSF56801 13 559 1.09E-111 T 23-10-2018 Mlab_1232 cea20d780893229544fbc1b8309da535 568 Gene3D G3DSA:3.40.50.12780 6 454 2.8E-89 T 23-10-2018 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 Gene3D G3DSA:2.40.180.10 3 486 2.3E-220 T 23-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 PRINTS PR00067 Catalase signature 83 101 6.1E-74 T 23-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 PRINTS PR00067 Catalase signature 320 346 6.1E-74 T 23-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 PRINTS PR00067 Catalase signature 288 315 6.1E-74 T 23-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 PRINTS PR00067 Catalase signature 21 44 6.1E-74 T 23-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 PRINTS PR00067 Catalase signature 123 141 6.1E-74 T 23-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 PRINTS PR00067 Catalase signature 104 121 6.1E-74 T 23-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 SMART SM01060 8 391 8.8E-283 T 23-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 Pfam PF00199 Catalase 8 388 3.1E-186 T 23-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 ProSitePatterns PS00438 Catalase proximal active site signature. 44 60 - T 23-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 SUPERFAMILY SSF56634 3 484 5.1E-209 T 23-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 PIRSF PIRSF038928 1 483 1.2E-221 T 23-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 Pfam PF06628 Catalase-related immune-responsive 418 475 1.5E-17 T 23-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_1574 3fd5a80a66b7b3d693dbece7f891c198 501 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 23-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Mlab_0427 6aff65b2714f2fbb95b03616ab15252a 264 Gene3D G3DSA:3.30.540.10 4 144 9.1E-26 T 23-10-2018 Mlab_0427 6aff65b2714f2fbb95b03616ab15252a 264 SUPERFAMILY SSF56655 7 262 4.58E-52 T 23-10-2018 Mlab_0427 6aff65b2714f2fbb95b03616ab15252a 264 Gene3D G3DSA:3.40.190.80 154 261 6.5E-25 T 23-10-2018 Mlab_0427 6aff65b2714f2fbb95b03616ab15252a 264 Pfam PF00459 Inositol monophosphatase family 38 255 1.1E-35 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Mlab_0427 6aff65b2714f2fbb95b03616ab15252a 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 2.2E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Mlab_0427 6aff65b2714f2fbb95b03616ab15252a 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 2.2E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Mlab_0427 6aff65b2714f2fbb95b03616ab15252a 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 2.2E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Mlab_0427 6aff65b2714f2fbb95b03616ab15252a 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 2.2E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Mlab_0427 6aff65b2714f2fbb95b03616ab15252a 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 174 195 2.2E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Mlab_0759 0726b30b54adde7c147ca20e00837cbd 240 Pfam PF14413 Thg1 C terminal domain 125 200 3.3E-7 T 23-10-2018 IPR025845 Thg1 C-terminal domain Reactome: R-HSA-6782315 Mlab_0759 0726b30b54adde7c147ca20e00837cbd 240 Gene3D G3DSA:3.30.70.3000 1 240 3.1E-73 T 23-10-2018 IPR038469 tRNAHis guanylyltransferase Thg1 superfamily Reactome: R-HSA-6782315 Mlab_0759 0726b30b54adde7c147ca20e00837cbd 240 Pfam PF04446 tRNAHis guanylyltransferase 2 116 9.5E-25 T 23-10-2018 IPR024956 tRNAHis guanylyltransferase catalytic domain GO:0000287|GO:0006400|GO:0008193 Reactome: R-HSA-6782315 Mlab_0642 b8ca7263b927edd945173ef4a35804b1 215 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Mlab_0642 b8ca7263b927edd945173ef4a35804b1 215 Gene3D G3DSA:1.20.120.1760 8 208 2.0E-39 T 23-10-2018 Mlab_0642 b8ca7263b927edd945173ef4a35804b1 215 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 90 1.4E-13 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Mlab_1487 486f50039516bbde69ada084fad89223 441 Pfam PF13180 PDZ domain 209 276 4.9E-9 T 23-10-2018 IPR001478 PDZ domain GO:0005515 Mlab_1487 486f50039516bbde69ada084fad89223 441 SUPERFAMILY SSF50156 209 303 1.71E-14 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 Mlab_1487 486f50039516bbde69ada084fad89223 441 Pfam PF02163 Peptidase family M50 120 428 1.8E-21 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 Mlab_1487 486f50039516bbde69ada084fad89223 441 Gene3D G3DSA:2.30.42.10 207 287 2.1E-12 T 23-10-2018 Mlab_1487 486f50039516bbde69ada084fad89223 441 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 103 122 4.5E-14 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 Mlab_1487 486f50039516bbde69ada084fad89223 441 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 126 140 4.5E-14 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 Mlab_1487 486f50039516bbde69ada084fad89223 441 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 142 157 4.5E-14 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 Mlab_1487 486f50039516bbde69ada084fad89223 441 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 158 170 4.5E-14 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 Mlab_0110 2344e197bc6355384127b5685529fd10 247 Pfam PF04002 RadC-like JAB domain 129 245 1.9E-36 T 23-10-2018 IPR025657 RadC-like JAB domain Mlab_0110 2344e197bc6355384127b5685529fd10 247 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 197 202 - T 23-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site Mlab_0110 2344e197bc6355384127b5685529fd10 247 TIGRFAM TIGR00608 radc: DNA repair protein RadC 39 238 5.9E-48 T 23-10-2018 IPR001405 Uncharacterised protein family UPF0758 Mlab_0110 2344e197bc6355384127b5685529fd10 247 Gene3D G3DSA:3.40.140.10 126 247 6.4E-36 T 23-10-2018 Mlab_1747 b9eda672f019c1bf7c1de43b98b1c0e5 271 Pfam PF00753 Metallo-beta-lactamase superfamily 24 111 2.4E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1747 b9eda672f019c1bf7c1de43b98b1c0e5 271 Gene3D G3DSA:3.60.15.10 1 267 4.6E-75 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1747 b9eda672f019c1bf7c1de43b98b1c0e5 271 SUPERFAMILY SSF56281 4 247 5.37E-32 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1747 b9eda672f019c1bf7c1de43b98b1c0e5 271 SMART SM00849 25 244 7.7E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0142 97b824d9863247c38adbb1976156aa9d 463 PIRSF PIRSF000726 1 463 2.4E-123 T 23-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Mlab_0142 97b824d9863247c38adbb1976156aa9d 463 SUPERFAMILY SSF55021 384 459 1.51E-20 T 23-10-2018 Mlab_0142 97b824d9863247c38adbb1976156aa9d 463 Gene3D G3DSA:3.40.1160.10 2 300 2.1E-97 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_0142 97b824d9863247c38adbb1976156aa9d 463 Pfam PF00696 Amino acid kinase family 1 287 3.6E-52 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Mlab_0142 97b824d9863247c38adbb1976156aa9d 463 Pfam PF13840 ACT domain 392 454 4.1E-9 T 23-10-2018 IPR027795 CASTOR, ACT domain Mlab_0142 97b824d9863247c38adbb1976156aa9d 463 ProSitePatterns PS00324 Aspartokinase signature. 4 12 - T 23-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Mlab_0142 97b824d9863247c38adbb1976156aa9d 463 Pfam PF01842 ACT domain 328 376 4.1E-7 T 23-10-2018 IPR002912 ACT domain Mlab_0142 97b824d9863247c38adbb1976156aa9d 463 Gene3D G3DSA:3.30.2130.10 301 463 4.1E-43 T 23-10-2018 Mlab_0142 97b824d9863247c38adbb1976156aa9d 463 SUPERFAMILY SSF55021 306 376 1.92E-16 T 23-10-2018 Mlab_0142 97b824d9863247c38adbb1976156aa9d 463 SUPERFAMILY SSF53633 2 301 1.7E-81 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_0142 97b824d9863247c38adbb1976156aa9d 463 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 456 5.8E-133 T 23-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Mlab_0381 27a783344b831b900bdd0974294d5cb0 324 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 63 291 1.5E-29 T 23-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 Mlab_0381 27a783344b831b900bdd0974294d5cb0 324 Gene3D G3DSA:3.10.310.10 62 159 8.7E-39 T 23-10-2018 Mlab_0381 27a783344b831b900bdd0974294d5cb0 324 Gene3D G3DSA:3.10.310.10 160 303 8.7E-39 T 23-10-2018 Mlab_0381 27a783344b831b900bdd0974294d5cb0 324 SUPERFAMILY SSF54506 63 322 6.89E-33 T 23-10-2018 Mlab_0381 27a783344b831b900bdd0974294d5cb0 324 PIRSF PIRSF016184 57 323 2.9E-27 T 23-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 Mlab_0381 27a783344b831b900bdd0974294d5cb0 324 Pfam PF02567 Phenazine biosynthesis-like protein 63 316 1.9E-27 T 23-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 Mlab_0187 b6251cde08bbc3749e10bb89dd494655 591 Gene3D G3DSA:1.10.569.10 241 418 3.8E-138 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 Mlab_0187 b6251cde08bbc3749e10bb89dd494655 591 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 590 5.1E-137 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Mlab_0187 b6251cde08bbc3749e10bb89dd494655 591 SUPERFAMILY SSF48310 213 590 1.44E-130 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Mlab_0187 b6251cde08bbc3749e10bb89dd494655 591 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 205 1.0E-73 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Mlab_0187 b6251cde08bbc3749e10bb89dd494655 591 SMART SM00790 4 207 4.0E-109 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Mlab_0187 b6251cde08bbc3749e10bb89dd494655 591 Gene3D G3DSA:1.10.599.10 239 590 3.8E-138 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 Mlab_0187 b6251cde08bbc3749e10bb89dd494655 591 Gene3D G3DSA:3.60.9.10 1 210 1.5E-80 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Mlab_0187 b6251cde08bbc3749e10bb89dd494655 591 SUPERFAMILY SSF56228 1 208 2.09E-70 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Mlab_1541 068bb4561e8b3c9eb8d7209f59861818 160 Pfam PF07790 Archaeal Type IV pilin, N-terminal 4 77 1.7E-18 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_1722 f84f979e9e463fab0ec920025feec17d 279 Gene3D G3DSA:3.40.50.150 13 181 1.5E-18 T 23-10-2018 Mlab_1722 f84f979e9e463fab0ec920025feec17d 279 SUPERFAMILY SSF53335 15 151 2.26E-20 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1722 f84f979e9e463fab0ec920025feec17d 279 Pfam PF13649 Methyltransferase domain 62 148 2.3E-11 T 23-10-2018 Mlab_0575 7a1d93b47bb2b1bc766f2ce33242572e 256 Pfam PF01493 GXGXG motif 104 216 4.0E-6 T 23-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 Mlab_0575 7a1d93b47bb2b1bc766f2ce33242572e 256 SUPERFAMILY SSF69336 17 225 1.03E-38 T 23-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Mlab_0575 7a1d93b47bb2b1bc766f2ce33242572e 256 Gene3D G3DSA:2.160.20.60 54 127 1.3E-5 T 23-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Mlab_0575 7a1d93b47bb2b1bc766f2ce33242572e 256 TIGRFAM TIGR03122 one_C_dehyd_C: formylmethanofuran dehydrogenase subunit C 5 248 7.7E-68 T 23-10-2018 IPR017550 Formylmethanofuran dehydrogenase subunit C GO:0015948|GO:0018493|GO:0046914|GO:0055114 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 Mlab_1248 5301e7c78fc78ee1dbb632c08dd6ca18 94 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 17 89 1.4E-15 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 Mlab_1248 5301e7c78fc78ee1dbb632c08dd6ca18 94 Gene3D G3DSA:3.30.1360.10 2 94 1.0E-20 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1248 5301e7c78fc78ee1dbb632c08dd6ca18 94 SUPERFAMILY SSF55257 4 93 3.66E-18 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1569 b374bdbc1edfed487f017db39e4e458b 122 Pfam PF03874 RNA polymerase Rpb4 12 121 1.6E-9 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 Mlab_1569 b374bdbc1edfed487f017db39e4e458b 122 SUPERFAMILY SSF47819 1 118 2.96E-24 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 Mlab_1569 b374bdbc1edfed487f017db39e4e458b 122 PIRSF PIRSF005053 1 122 4.3E-22 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) Mlab_1569 b374bdbc1edfed487f017db39e4e458b 122 Gene3D G3DSA:1.10.150.80 59 122 3.1E-15 T 23-10-2018 Mlab_0515 0b6309ae1ec32fe2d4a4062780344109 321 Hamap MF_01509 Replication factor C small subunit [rfcS]. 4 319 47.548 T 23-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 Mlab_0515 0b6309ae1ec32fe2d4a4062780344109 321 Gene3D G3DSA:1.10.8.60 163 227 1.1E-19 T 23-10-2018 Mlab_0515 0b6309ae1ec32fe2d4a4062780344109 321 SUPERFAMILY SSF52540 7 222 2.97E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0515 0b6309ae1ec32fe2d4a4062780344109 321 SMART SM00382 38 169 1.2E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0515 0b6309ae1ec32fe2d4a4062780344109 321 Pfam PF08542 Replication factor C C-terminal domain 228 314 8.2E-21 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 Mlab_0515 0b6309ae1ec32fe2d4a4062780344109 321 Gene3D G3DSA:1.20.272.10 228 320 6.1E-26 T 23-10-2018 Mlab_0515 0b6309ae1ec32fe2d4a4062780344109 321 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 159 1.5E-15 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_0515 0b6309ae1ec32fe2d4a4062780344109 321 Gene3D G3DSA:3.40.50.300 2 162 9.7E-55 T 23-10-2018 Mlab_0515 0b6309ae1ec32fe2d4a4062780344109 321 SUPERFAMILY SSF48019 229 316 2.58E-19 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Mlab_1284 bdbeea262e978882f7b1488c3b85afe5 248 PRINTS PR00783 Major intrinsic protein family signature 223 243 4.2E-52 T 23-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Mlab_1284 bdbeea262e978882f7b1488c3b85afe5 248 PRINTS PR00783 Major intrinsic protein family signature 179 201 4.2E-52 T 23-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Mlab_1284 bdbeea262e978882f7b1488c3b85afe5 248 PRINTS PR00783 Major intrinsic protein family signature 61 85 4.2E-52 T 23-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Mlab_1284 bdbeea262e978882f7b1488c3b85afe5 248 PRINTS PR00783 Major intrinsic protein family signature 98 117 4.2E-52 T 23-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Mlab_1284 bdbeea262e978882f7b1488c3b85afe5 248 PRINTS PR00783 Major intrinsic protein family signature 5 24 4.2E-52 T 23-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Mlab_1284 bdbeea262e978882f7b1488c3b85afe5 248 PRINTS PR00783 Major intrinsic protein family signature 148 166 4.2E-52 T 23-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Mlab_1284 bdbeea262e978882f7b1488c3b85afe5 248 Gene3D G3DSA:1.20.1080.10 1 245 1.2E-83 T 23-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 Mlab_1284 bdbeea262e978882f7b1488c3b85afe5 248 Pfam PF00230 Major intrinsic protein 3 240 1.0E-54 T 23-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Mlab_1284 bdbeea262e978882f7b1488c3b85afe5 248 SUPERFAMILY SSF81338 3 244 4.19E-65 T 23-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 Mlab_1284 bdbeea262e978882f7b1488c3b85afe5 248 TIGRFAM TIGR00861 MIP: MIP family channel proteins 9 240 7.3E-59 T 23-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Mlab_1284 bdbeea262e978882f7b1488c3b85afe5 248 ProSitePatterns PS00221 MIP family signature. 79 87 - T 23-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 Mlab_1626 ed9a4d387ed034718ce0aa03e3e7fd02 387 Gene3D G3DSA:3.40.47.10 3 387 1.3E-131 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 Mlab_1626 ed9a4d387ed034718ce0aa03e3e7fd02 387 SUPERFAMILY SSF53901 247 374 1.83E-31 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 Mlab_1626 ed9a4d387ed034718ce0aa03e3e7fd02 387 Pfam PF02803 Thiolase, C-terminal domain 260 371 2.5E-12 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Mlab_1626 ed9a4d387ed034718ce0aa03e3e7fd02 387 SUPERFAMILY SSF53901 3 230 1.11E-45 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 Mlab_1626 ed9a4d387ed034718ce0aa03e3e7fd02 387 Pfam PF00108 Thiolase, N-terminal domain 4 223 2.1E-28 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Mlab_1626 ed9a4d387ed034718ce0aa03e3e7fd02 387 PIRSF PIRSF000429 1 384 1.9E-74 T 23-10-2018 IPR002155 Thiolase GO:0016747 Mlab_0478 6c578630c2fdb322fb37b3688f865c6c 92 SUPERFAMILY SSF54285 4 92 5.67E-12 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Mlab_0478 6c578630c2fdb322fb37b3688f865c6c 92 Gene3D G3DSA:3.10.20.30 2 92 4.7E-15 T 23-10-2018 IPR012675 Beta-grasp domain superfamily Mlab_0478 6c578630c2fdb322fb37b3688f865c6c 92 Pfam PF02597 ThiS family 9 92 2.5E-7 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Mlab_0605 e9810d3592588bd8a04f2b39b8b7f84c 567 SUPERFAMILY SSF52518 1 172 1.79E-59 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_0605 e9810d3592588bd8a04f2b39b8b7f84c 567 Gene3D G3DSA:3.40.50.970 1 179 3.8E-68 T 23-10-2018 Mlab_0605 e9810d3592588bd8a04f2b39b8b7f84c 567 Gene3D G3DSA:3.40.50.970 358 563 2.3E-75 T 23-10-2018 Mlab_0605 e9810d3592588bd8a04f2b39b8b7f84c 567 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 1.2E-54 T 23-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Mlab_0605 e9810d3592588bd8a04f2b39b8b7f84c 567 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 5 558 1.2E-257 T 23-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Mlab_0605 e9810d3592588bd8a04f2b39b8b7f84c 567 Gene3D G3DSA:3.40.50.1220 189 355 3.0E-67 T 23-10-2018 Mlab_0605 e9810d3592588bd8a04f2b39b8b7f84c 567 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 533 8.9E-55 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Mlab_0605 e9810d3592588bd8a04f2b39b8b7f84c 567 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 424 443 - T 23-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Mlab_0605 e9810d3592588bd8a04f2b39b8b7f84c 567 SUPERFAMILY SSF52467 188 356 2.73E-67 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Mlab_0605 e9810d3592588bd8a04f2b39b8b7f84c 567 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 328 2.1E-52 T 23-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Mlab_0605 e9810d3592588bd8a04f2b39b8b7f84c 567 SUPERFAMILY SSF52518 364 556 9.21E-74 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_1127 5d17e39b66e17033565ad39918ece941 170 Gene3D G3DSA:3.40.50.300 1 170 2.4E-32 T 23-10-2018 Mlab_1127 5d17e39b66e17033565ad39918ece941 170 Hamap MF_00039 Putative adenylate kinase. 1 158 21.131 T 23-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Mlab_1127 5d17e39b66e17033565ad39918ece941 170 Pfam PF13238 AAA domain 3 113 4.5E-17 T 23-10-2018 Mlab_1127 5d17e39b66e17033565ad39918ece941 170 SUPERFAMILY SSF52540 1 150 7.07E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0645 69fd3952dbd359c257c739f11ae0c8a7 406 Pfam PF01676 Metalloenzyme superfamily 5 394 8.2E-40 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 Mlab_0645 69fd3952dbd359c257c739f11ae0c8a7 406 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 40 212 3.6E-51 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_0645 69fd3952dbd359c257c739f11ae0c8a7 406 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 397 40.256 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_0645 69fd3952dbd359c257c739f11ae0c8a7 406 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 7 396 5.7E-126 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_0645 69fd3952dbd359c257c739f11ae0c8a7 406 PIRSF PIRSF006392 1 402 1.7E-136 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_0645 69fd3952dbd359c257c739f11ae0c8a7 406 Gene3D G3DSA:3.40.720.10 7 392 2.1E-115 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Mlab_0645 69fd3952dbd359c257c739f11ae0c8a7 406 Gene3D G3DSA:3.30.70.2130 81 234 2.1E-115 T 23-10-2018 Mlab_0645 69fd3952dbd359c257c739f11ae0c8a7 406 SUPERFAMILY SSF53649 4 399 5.03E-34 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Mlab_1586 0cc7449f1fee0c35977f8f25f479f382 443 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 2 259 33.941 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 Mlab_1586 0cc7449f1fee0c35977f8f25f479f382 443 Pfam PF04414 D-aminoacyl-tRNA deacylase 60 256 1.5E-62 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 Mlab_1586 0cc7449f1fee0c35977f8f25f479f382 443 Gene3D G3DSA:3.40.50.10700 176 269 5.6E-18 T 23-10-2018 Mlab_1586 0cc7449f1fee0c35977f8f25f479f382 443 SUPERFAMILY SSF56281 381 433 9.33E-5 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1586 0cc7449f1fee0c35977f8f25f479f382 443 SUPERFAMILY SSF142535 3 268 2.22E-73 T 23-10-2018 Mlab_1586 0cc7449f1fee0c35977f8f25f479f382 443 Gene3D G3DSA:3.40.630.50 1 172 2.6E-43 T 23-10-2018 Mlab_0249 1dabf59fa9dab891ab6f2a6aea33c076 141 SUPERFAMILY SSF52540 1 117 1.67E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0249 1dabf59fa9dab891ab6f2a6aea33c076 141 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 3 115 4.3E-27 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 Mlab_0249 1dabf59fa9dab891ab6f2a6aea33c076 141 Gene3D G3DSA:3.40.50.300 1 136 1.7E-28 T 23-10-2018 Mlab_0249 1dabf59fa9dab891ab6f2a6aea33c076 141 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 3 109 5.0E-20 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 5 418 5.6E-154 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 SUPERFAMILY SSF55003 252 448 4.32E-54 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 Gene3D G3DSA:3.30.70.590 276 435 1.5E-50 T 23-10-2018 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 Gene3D G3DSA:3.30.70.1550 351 398 1.5E-50 T 23-10-2018 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 Hamap MF_01264 CCA-adding enzyme [cca]. 1 464 176.151 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 Gene3D G3DSA:3.30.460.10 15 147 3.9E-86 T 23-10-2018 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 Pfam PF09249 tRNA nucleotidyltransferase, second domain 150 265 7.4E-38 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 Gene3D G3DSA:1.10.1410.30 8 265 3.9E-86 T 23-10-2018 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 PIRSF PIRSF005335 3 451 3.2E-134 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 SUPERFAMILY SSF81631 148 266 1.73E-30 T 23-10-2018 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 SUPERFAMILY SSF81301 6 145 9.0E-31 T 23-10-2018 Mlab_0369 0d090317e1ca47599fd422d2dc82bd9a 464 Pfam PF01909 Nucleotidyltransferase domain 29 134 4.7E-12 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Mlab_0795 47bfd5ad75527a71ac256d8cbbfbfb8d 282 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 277 21.912 T 23-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 Mlab_0795 47bfd5ad75527a71ac256d8cbbfbfb8d 282 Pfam PF01040 UbiA prenyltransferase family 21 254 1.0E-43 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 Mlab_0795 47bfd5ad75527a71ac256d8cbbfbfb8d 282 Gene3D G3DSA:1.10.357.140 15 151 2.6E-17 T 23-10-2018 Mlab_0621 5c00448a52390f84745c5e189307d6ba 280 Pfam PF12706 Beta-lactamase superfamily domain 24 225 5.2E-17 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0621 5c00448a52390f84745c5e189307d6ba 280 SMART SM00849 11 184 3.0E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0621 5c00448a52390f84745c5e189307d6ba 280 SUPERFAMILY SSF56281 1 257 2.88E-31 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 Gene3D G3DSA:3.40.190.10 4 200 4.3E-63 T 23-10-2018 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 303 515 7.7E-46 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 SUPERFAMILY SSF54782 212 279 3.14E-10 T 23-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 Gene3D G3DSA:3.30.160.40 214 293 3.9E-6 T 23-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 302 538 5.2E-88 T 23-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 218 280 3.6E-7 T 23-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 Gene3D G3DSA:3.30.950.10 418 542 8.9E-45 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 Gene3D G3DSA:3.40.190.10 99 195 4.3E-63 T 23-10-2018 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 262 1.0E-77 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 SUPERFAMILY SSF53850 2 202 1.3E-59 T 23-10-2018 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 223 239 - T 23-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 PRINTS PR00151 Porphobilinogen deaminase signature 137 154 6.5E-27 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 PRINTS PR00151 Porphobilinogen deaminase signature 72 91 6.5E-27 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 PRINTS PR00151 Porphobilinogen deaminase signature 41 61 6.5E-27 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 PRINTS PR00151 Porphobilinogen deaminase signature 222 239 6.5E-27 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 201 5.7E-63 T 23-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 Gene3D G3DSA:3.40.1010.10 300 417 1.8E-39 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Mlab_0526 569cf65475f5f2142b2ca5397190c33b 542 SUPERFAMILY SSF53790 300 539 9.68E-73 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Mlab_0441 993469349b0fcb4700a653eb86ffd618 348 Pfam PF05726 Pirin C-terminal cupin domain 209 309 1.3E-23 T 23-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 Mlab_0441 993469349b0fcb4700a653eb86ffd618 348 SUPERFAMILY SSF51182 52 314 1.93E-59 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily Mlab_0441 993469349b0fcb4700a653eb86ffd618 348 Pfam PF02678 Pirin 53 140 1.7E-23 T 23-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 Mlab_0441 993469349b0fcb4700a653eb86ffd618 348 PIRSF PIRSF006232 23 317 3.1E-69 T 23-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 Mlab_0441 993469349b0fcb4700a653eb86ffd618 348 Gene3D G3DSA:2.60.120.10 58 304 5.6E-64 T 23-10-2018 IPR014710 RmlC-like jelly roll fold Mlab_0441 993469349b0fcb4700a653eb86ffd618 348 Gene3D G3DSA:2.60.120.10 162 278 5.6E-64 T 23-10-2018 IPR014710 RmlC-like jelly roll fold Mlab_0128 9ee42922d311232ac7e7d0757c1b4560 136 SUPERFAMILY SSF69819 3 136 7.72E-25 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 Mlab_0128 9ee42922d311232ac7e7d0757c1b4560 136 Pfam PF01951 Archease protein family (MTH1598/TM1083) 3 136 6.0E-29 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 Mlab_0128 9ee42922d311232ac7e7d0757c1b4560 136 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 7 135 2.0E-9 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 Mlab_0128 9ee42922d311232ac7e7d0757c1b4560 136 Gene3D G3DSA:3.55.10.10 1 136 8.2E-28 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 Gene3D G3DSA:1.10.240.10 199 317 1.6E-35 T 23-10-2018 Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 Hamap MF_02008 Tyrosine--tRNA ligase [tyrS]. 1 313 49.174 T 23-10-2018 IPR023684 Tyrosine-tRNA ligase, type 3 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 Gene3D G3DSA:3.40.50.620 1 198 6.7E-66 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 5 239 2.4E-53 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 SUPERFAMILY SSF52374 3 315 4.9E-71 T 23-10-2018 Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 144 159 1.1E-16 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 40 62 1.1E-16 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 183 1.1E-16 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 194 206 1.1E-16 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 PIRSF PIRSF006588 1 317 1.4E-111 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 37 46 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1734 3e2dc6052c8cec3f78d9ef7f0e965c0d 317 Pfam PF00579 tRNA synthetases class I (W and Y) 29 305 7.8E-51 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0378 4b79414f23cd00d7eb49372fcc2433d9 260 SUPERFAMILY SSF52540 9 243 1.04E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0378 4b79414f23cd00d7eb49372fcc2433d9 260 Pfam PF00005 ABC transporter 28 167 3.7E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0378 4b79414f23cd00d7eb49372fcc2433d9 260 Gene3D G3DSA:3.40.50.300 7 257 1.1E-66 T 23-10-2018 Mlab_0378 4b79414f23cd00d7eb49372fcc2433d9 260 SMART SM00382 37 216 3.6E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0378 4b79414f23cd00d7eb49372fcc2433d9 260 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0259 5f321a779173d17ee2635e142994d6a2 469 SMART SM00382 37 228 1.3E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0259 5f321a779173d17ee2635e142994d6a2 469 SMART SM00382 274 460 2.7E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0259 5f321a779173d17ee2635e142994d6a2 469 SUPERFAMILY SSF52540 264 463 1.17E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0259 5f321a779173d17ee2635e142994d6a2 469 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 41 54 - T 23-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Mlab_0259 5f321a779173d17ee2635e142994d6a2 469 Pfam PF00005 ABC transporter 29 178 4.7E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0259 5f321a779173d17ee2635e142994d6a2 469 Pfam PF00005 ABC transporter 265 411 6.3E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0259 5f321a779173d17ee2635e142994d6a2 469 SUPERFAMILY SSF52540 4 222 5.99E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0259 5f321a779173d17ee2635e142994d6a2 469 Gene3D G3DSA:3.40.50.300 3 225 2.6E-57 T 23-10-2018 Mlab_0259 5f321a779173d17ee2635e142994d6a2 469 Gene3D G3DSA:3.40.50.300 243 467 6.3E-60 T 23-10-2018 Mlab_0505 2654d5b1e91fe8a06a8b977fcbda9a1b 208 SUPERFAMILY SSF55136 132 207 4.19E-8 T 23-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily Mlab_0505 2654d5b1e91fe8a06a8b977fcbda9a1b 208 Pfam PF06445 GyrI-like small molecule binding domain 20 203 9.7E-32 T 23-10-2018 IPR029442 GyrI-like small molecule binding domain Mlab_0505 2654d5b1e91fe8a06a8b977fcbda9a1b 208 Gene3D G3DSA:3.20.80.10 1 206 2.9E-83 T 23-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily Mlab_0505 2654d5b1e91fe8a06a8b977fcbda9a1b 208 PIRSF PIRSF031644 1 208 3.8E-77 T 23-10-2018 IPR008319 Uncharacterised conserved protein UCP031644 Mlab_0599 e5c1adbbb1f43ceec506869f0e0490be 288 Pfam PF02153 Prephenate dehydrogenase 52 260 8.0E-39 T 23-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 Mlab_0599 e5c1adbbb1f43ceec506869f0e0490be 288 Gene3D G3DSA:3.40.50.720 5 162 1.6E-39 T 23-10-2018 Mlab_0599 e5c1adbbb1f43ceec506869f0e0490be 288 Gene3D G3DSA:1.10.3660.10 164 288 1.2E-39 T 23-10-2018 Mlab_0599 e5c1adbbb1f43ceec506869f0e0490be 288 SUPERFAMILY SSF51735 16 156 3.6E-33 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0599 e5c1adbbb1f43ceec506869f0e0490be 288 SUPERFAMILY SSF48179 158 283 1.04E-32 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Mlab_0966 4a71adb49c9316f85b9c7e51eb33d381 447 SUPERFAMILY SSF51905 12 441 3.75E-36 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0966 4a71adb49c9316f85b9c7e51eb33d381 447 Gene3D G3DSA:3.50.50.60 4 446 9.3E-123 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0966 4a71adb49c9316f85b9c7e51eb33d381 447 Pfam PF01593 Flavin containing amine oxidoreductase 18 391 6.5E-24 T 23-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 Mlab_0762 0f74cad79dce0a85c534261628ffc549 256 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 16 80 2.9E-13 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal Mlab_0762 0f74cad79dce0a85c534261628ffc549 256 SUPERFAMILY SSF46785 7 98 5.94E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0762 0f74cad79dce0a85c534261628ffc549 256 Gene3D G3DSA:1.10.10.10 5 103 3.3E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1581 0cc4f63b9b9ce1123d882b63444d1ca1 213 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 3 213 34.979 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 Mlab_1581 0cc4f63b9b9ce1123d882b63444d1ca1 213 PIRSF PIRSF002155 1 213 2.2E-56 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1581 0cc4f63b9b9ce1123d882b63444d1ca1 213 Pfam PF00687 Ribosomal protein L1p/L10e family 20 208 4.2E-44 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein Mlab_1581 0cc4f63b9b9ce1123d882b63444d1ca1 213 Gene3D G3DSA:3.30.190.20 18 208 8.3E-64 T 23-10-2018 Mlab_1581 0cc4f63b9b9ce1123d882b63444d1ca1 213 ProSitePatterns PS01199 Ribosomal protein L1 signature. 113 132 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1581 0cc4f63b9b9ce1123d882b63444d1ca1 213 Gene3D G3DSA:3.40.50.790 58 148 8.3E-64 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich Mlab_1581 0cc4f63b9b9ce1123d882b63444d1ca1 213 SUPERFAMILY SSF56808 14 212 9.29E-54 T 23-10-2018 IPR023674 Ribosomal protein L1-like Mlab_1200 b8f910ab9d265c514cedc6685afc7f4f 1076 Pfam PF04851 Type III restriction enzyme, res subunit 13 253 1.3E-14 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Mlab_1200 b8f910ab9d265c514cedc6685afc7f4f 1076 Gene3D G3DSA:3.40.50.300 397 660 2.4E-6 T 23-10-2018 Mlab_1200 b8f910ab9d265c514cedc6685afc7f4f 1076 SUPERFAMILY SSF52540 6 295 4.65E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1200 b8f910ab9d265c514cedc6685afc7f4f 1076 Gene3D G3DSA:3.40.50.300 69 271 5.2E-11 T 23-10-2018 Mlab_0756 31d0244771d6efa776aa35c6ab67703a 551 SUPERFAMILY SSF81585 482 546 1.9E-6 T 23-10-2018 Mlab_0756 31d0244771d6efa776aa35c6ab67703a 551 Gene3D G3DSA:3.80.30.20 180 419 1.1E-16 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Mlab_0756 31d0244771d6efa776aa35c6ab67703a 551 SUPERFAMILY SSF102114 182 405 6.47E-16 T 23-10-2018 Mlab_0756 31d0244771d6efa776aa35c6ab67703a 551 Pfam PF04055 Radical SAM superfamily 193 370 2.5E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0756 31d0244771d6efa776aa35c6ab67703a 551 SMART SM00729 178 425 5.2E-13 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 ProSitePatterns PS00841 XPG protein signature 1. 74 88 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 Gene3D G3DSA:3.40.50.1010 18 333 7.8E-85 T 23-10-2018 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 Pfam PF00867 XPG I-region 142 235 1.4E-23 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 Pfam PF00752 XPG N-terminal domain 25 101 3.4E-15 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 333 113.183 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 SUPERFAMILY SSF88723 22 235 2.58E-52 T 23-10-2018 IPR029060 PIN-like domain superfamily Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 333 1.0E-135 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 SMART SM00279 222 255 4.0E-11 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 22 36 1.1E-30 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 161 181 1.1E-30 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 225 240 1.1E-30 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 76 95 1.1E-30 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 140 157 1.1E-30 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 SMART SM00485 1 102 6.1E-31 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 SUPERFAMILY SSF47807 220 333 1.42E-22 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily Mlab_0356 9cc0636ca781d40407743dc0b84ece9e 333 SMART SM00484 141 220 2.2E-18 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 Mlab_1649 5757d4bff2f4aacd6daa8ded2886c951 357 PIRSF PIRSF001456 1 355 6.2E-117 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Mlab_1649 5757d4bff2f4aacd6daa8ded2886c951 357 SUPERFAMILY SSF103263 1 353 1.83E-101 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Mlab_1649 5757d4bff2f4aacd6daa8ded2886c951 357 Hamap MF_00300 Chorismate synthase [aroC]. 8 356 30.153 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Mlab_1649 5757d4bff2f4aacd6daa8ded2886c951 357 Pfam PF01264 Chorismate synthase 9 351 1.3E-108 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Mlab_1649 5757d4bff2f4aacd6daa8ded2886c951 357 TIGRFAM TIGR00033 aroC: chorismate synthase 9 353 2.4E-104 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Mlab_1649 5757d4bff2f4aacd6daa8ded2886c951 357 ProSitePatterns PS00789 Chorismate synthase signature 3. 325 341 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Mlab_1649 5757d4bff2f4aacd6daa8ded2886c951 357 Gene3D G3DSA:3.60.150.10 1 355 2.4E-119 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Mlab_1649 5757d4bff2f4aacd6daa8ded2886c951 357 ProSitePatterns PS00788 Chorismate synthase signature 2. 121 137 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Mlab_1744 50f0e64ab3c4647955d4567edce468eb 342 PIRSF PIRSF016158 1 341 5.6E-107 T 23-10-2018 IPR024190 Methenyltetrahydromethanopterin dehydrogenase, Hmd-type KEGG: 00680+1.12.98.2|MetaCyc: PWY-7784 Mlab_1744 50f0e64ab3c4647955d4567edce468eb 342 Pfam PF03201 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase 242 338 3.3E-38 T 23-10-2018 IPR004889 H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase, C-terminal KEGG: 00680+1.12.98.2|MetaCyc: PWY-7784 Mlab_1744 50f0e64ab3c4647955d4567edce468eb 342 SUPERFAMILY SSF48179 242 340 3.16E-38 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Mlab_1744 50f0e64ab3c4647955d4567edce468eb 342 TIGRFAM TIGR01723 hmd_TIGR: 5,10-methenyltetrahydromethanopterin hydrogenase 1 340 3.2E-176 T 23-10-2018 IPR010062 5,10-methenyltetrahydromethanopterin hydrogenase GO:0019386|GO:0047068|GO:0055114 KEGG: 00680+1.12.98.2|MetaCyc: PWY-7784 Mlab_1744 50f0e64ab3c4647955d4567edce468eb 342 SUPERFAMILY SSF51735 1 241 1.02E-62 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1744 50f0e64ab3c4647955d4567edce468eb 342 Gene3D G3DSA:1.20.120.1300 252 341 4.0E-42 T 23-10-2018 IPR038182 HMD, C-terminal domain superfamily KEGG: 00680+1.12.98.2|MetaCyc: PWY-7784 Mlab_1744 50f0e64ab3c4647955d4567edce468eb 342 Gene3D G3DSA:3.40.50.720 1 251 8.3E-121 T 23-10-2018 Mlab_1744 50f0e64ab3c4647955d4567edce468eb 342 Hamap MF_01090 5,10-methenyltetrahydromethanopterin hydrogenase [hmd]. 1 342 197.938 T 23-10-2018 IPR010062 5,10-methenyltetrahydromethanopterin hydrogenase GO:0019386|GO:0047068|GO:0055114 KEGG: 00680+1.12.98.2|MetaCyc: PWY-7784 Mlab_0598 a294030e3a4e31ed7d2d07ee358b44ab 265 Gene3D G3DSA:3.30.70.260 185 259 1.4E-24 T 23-10-2018 Mlab_0598 a294030e3a4e31ed7d2d07ee358b44ab 265 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 213 220 - T 23-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Mlab_0598 a294030e3a4e31ed7d2d07ee358b44ab 265 Pfam PF00800 Prephenate dehydratase 4 173 1.7E-46 T 23-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Mlab_0598 a294030e3a4e31ed7d2d07ee358b44ab 265 Gene3D G3DSA:3.40.190.10 6 172 2.8E-43 T 23-10-2018 Mlab_0598 a294030e3a4e31ed7d2d07ee358b44ab 265 SUPERFAMILY SSF53850 1 180 4.23E-41 T 23-10-2018 Mlab_0598 a294030e3a4e31ed7d2d07ee358b44ab 265 SUPERFAMILY SSF55021 169 260 2.55E-20 T 23-10-2018 Mlab_0598 a294030e3a4e31ed7d2d07ee358b44ab 265 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 150 172 - T 23-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Mlab_0598 a294030e3a4e31ed7d2d07ee358b44ab 265 Gene3D G3DSA:3.40.190.10 82 164 2.8E-43 T 23-10-2018 Mlab_0598 a294030e3a4e31ed7d2d07ee358b44ab 265 Pfam PF01842 ACT domain 193 250 1.1E-11 T 23-10-2018 IPR002912 ACT domain Mlab_0081 89e09249d99e8f4e5b173f778251445f 333 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 332 46.734 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0081 89e09249d99e8f4e5b173f778251445f 333 Gene3D G3DSA:4.10.960.10 5 253 7.2E-124 T 23-10-2018 Mlab_0081 89e09249d99e8f4e5b173f778251445f 333 SUPERFAMILY SSF50447 4 333 5.12E-98 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Mlab_0081 89e09249d99e8f4e5b173f778251445f 333 Gene3D G3DSA:3.30.1430.10 78 184 7.2E-124 T 23-10-2018 Mlab_0081 89e09249d99e8f4e5b173f778251445f 333 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 331 1.4E-147 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0081 89e09249d99e8f4e5b173f778251445f 333 ProSitePatterns PS00474 Ribosomal protein L3 signature. 189 212 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site Mlab_0081 89e09249d99e8f4e5b173f778251445f 333 Gene3D G3DSA:2.40.30.10 39 313 7.2E-124 T 23-10-2018 Mlab_0081 89e09249d99e8f4e5b173f778251445f 333 Pfam PF00297 Ribosomal protein L3 5 333 2.2E-86 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0014 fa36173858876042bfebee6def98070d 160 Gene3D G3DSA:3.40.50.1450 7 160 5.0E-35 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily Mlab_0014 fa36173858876042bfebee6def98070d 160 SUPERFAMILY SSF53163 7 159 6.28E-34 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily Mlab_0014 fa36173858876042bfebee6def98070d 160 Pfam PF01750 Hydrogenase maturation protease 27 157 5.8E-23 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_0014 fa36173858876042bfebee6def98070d 160 PRINTS PR00446 Hydrogen uptake protein signature 63 73 2.6E-19 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_0014 fa36173858876042bfebee6def98070d 160 PRINTS PR00446 Hydrogen uptake protein signature 74 90 2.6E-19 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_0014 fa36173858876042bfebee6def98070d 160 PRINTS PR00446 Hydrogen uptake protein signature 20 31 2.6E-19 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_0014 fa36173858876042bfebee6def98070d 160 PRINTS PR00446 Hydrogen uptake protein signature 39 56 2.6E-19 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_0014 fa36173858876042bfebee6def98070d 160 PRINTS PR00446 Hydrogen uptake protein signature 8 20 2.6E-19 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_0014 fa36173858876042bfebee6def98070d 160 TIGRFAM TIGR00130 frhD: coenzyme F420-reducing hydrogenase, FrhD protein 7 159 5.5E-44 T 23-10-2018 IPR004411 Peptidase A31, coenzyme F420-reducing hydrogenase delta subunit GO:0006464|GO:0008233 Mlab_0014 fa36173858876042bfebee6def98070d 160 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 10 158 9.8E-37 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_1385 23d987f095f6a76650b76bb3364ed1b3 151 Pfam PF07650 KH domain 20 74 1.5E-13 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1385 23d987f095f6a76650b76bb3364ed1b3 151 SUPERFAMILY SSF54814 20 76 1.7E-10 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Mlab_1385 23d987f095f6a76650b76bb3364ed1b3 151 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 4 144 25.979 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal Mlab_1385 23d987f095f6a76650b76bb3364ed1b3 151 Gene3D G3DSA:3.30.300.20 77 145 6.2E-17 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta Mlab_1385 23d987f095f6a76650b76bb3364ed1b3 151 Gene3D G3DSA:3.30.300.20 4 76 2.8E-23 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta Mlab_1385 23d987f095f6a76650b76bb3364ed1b3 151 SMART SM00322 35 102 5.9E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 Mlab_1385 23d987f095f6a76650b76bb3364ed1b3 151 SUPERFAMILY SSF54814 78 132 6.54E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Mlab_1385 23d987f095f6a76650b76bb3364ed1b3 151 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 10 137 2.8E-34 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal Mlab_0244 1a6d95348a3c8a9e68fc2b6f89994032 438 SUPERFAMILY SSF53706 6 431 4.71E-68 T 23-10-2018 Mlab_0244 1a6d95348a3c8a9e68fc2b6f89994032 438 PIRSF PIRSF005646 2 436 1.3E-176 T 23-10-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 Mlab_0244 1a6d95348a3c8a9e68fc2b6f89994032 438 Gene3D G3DSA:3.40.50.740 60 119 7.2E-20 T 23-10-2018 Mlab_0244 1a6d95348a3c8a9e68fc2b6f89994032 438 Gene3D G3DSA:3.40.50.740 295 426 2.1E-7 T 23-10-2018 Mlab_0244 1a6d95348a3c8a9e68fc2b6f89994032 438 Gene3D G3DSA:3.40.228.10 232 291 2.1E-7 T 23-10-2018 Mlab_0244 1a6d95348a3c8a9e68fc2b6f89994032 438 Gene3D G3DSA:3.40.228.10 120 218 7.2E-20 T 23-10-2018 Mlab_0244 1a6d95348a3c8a9e68fc2b6f89994032 438 TIGRFAM TIGR03129 one_C_dehyd_B: formylmethanofuran dehydrogenase subunit B 7 429 4.3E-181 T 23-10-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 Mlab_0244 1a6d95348a3c8a9e68fc2b6f89994032 438 Pfam PF00384 Molybdopterin oxidoreductase 53 387 2.2E-11 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 391 1.4E-153 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 2 390 1.1E-159 T 23-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 ProSitePatterns PS01244 Aconitase family signature 2. 325 338 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 Pfam PF00330 Aconitase family (aconitate hydratase) 5 384 2.1E-90 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 SUPERFAMILY SSF53732 4 392 2.22E-131 T 23-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 Gene3D G3DSA:3.30.499.20 1 243 1.9E-89 T 23-10-2018 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 1 392 44.289 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 PRINTS PR00415 Aconitase family signature 101 116 6.5E-17 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 PRINTS PR00415 Aconitase family signature 87 100 6.5E-17 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 PRINTS PR00415 Aconitase family signature 325 338 6.5E-17 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 PRINTS PR00415 Aconitase family signature 76 84 6.5E-17 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 PRINTS PR00415 Aconitase family signature 163 176 6.5E-17 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 PRINTS PR00415 Aconitase family signature 177 190 6.5E-17 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Mlab_0607 cd18946e253b2244e300902ccab94aa8 392 Gene3D G3DSA:3.30.499.10 246 392 3.6E-55 T 23-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Mlab_0528 aa5e10d8a4260cd489b45e243c7515a9 57 Gene3D G3DSA:3.30.70.20 1 57 1.6E-16 T 23-10-2018 Mlab_0528 aa5e10d8a4260cd489b45e243c7515a9 57 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0528 aa5e10d8a4260cd489b45e243c7515a9 57 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 39 50 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0528 aa5e10d8a4260cd489b45e243c7515a9 57 SUPERFAMILY SSF54862 2 56 2.56E-17 T 23-10-2018 Mlab_0528 aa5e10d8a4260cd489b45e243c7515a9 57 Pfam PF13187 4Fe-4S dicluster domain 9 54 1.3E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0272 61c1fd90930c730f6a61fc98f298932a 240 SUPERFAMILY SSF102705 1 229 9.03E-50 T 23-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily Mlab_0272 61c1fd90930c730f6a61fc98f298932a 240 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 223 6.7E-43 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Mlab_0272 61c1fd90930c730f6a61fc98f298932a 240 Gene3D G3DSA:3.40.1390.30 6 221 1.6E-44 T 23-10-2018 Mlab_0272 61c1fd90930c730f6a61fc98f298932a 240 Gene3D G3DSA:3.40.1390.30 99 209 1.6E-44 T 23-10-2018 Mlab_0303 306cd055909d51aef8385c6a7f3c4d31 94 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 1.0E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0303 306cd055909d51aef8385c6a7f3c4d31 94 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.0E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0303 306cd055909d51aef8385c6a7f3c4d31 94 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 1.0E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0303 306cd055909d51aef8385c6a7f3c4d31 94 SMART SM00418 8 86 1.5E-21 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0303 306cd055909d51aef8385c6a7f3c4d31 94 SUPERFAMILY SSF46785 5 89 4.25E-25 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0303 306cd055909d51aef8385c6a7f3c4d31 94 Pfam PF12840 Helix-turn-helix domain 8 63 6.9E-15 T 23-10-2018 Mlab_0303 306cd055909d51aef8385c6a7f3c4d31 94 Gene3D G3DSA:1.10.10.10 5 94 9.1E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1047 3e8e35cbaa12e6fce3260069f791daaf 282 SUPERFAMILY SSF51695 38 271 2.88E-44 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Mlab_1047 3e8e35cbaa12e6fce3260069f791daaf 282 Gene3D G3DSA:3.20.20.190 36 281 6.1E-39 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Mlab_1047 3e8e35cbaa12e6fce3260069f791daaf 282 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 41 147 2.8E-21 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Mlab_1084 16a6ecb568755b99c6f7ce28d100b6e6 104 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 104 36.227 T 23-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 Mlab_1084 16a6ecb568755b99c6f7ce28d100b6e6 104 Pfam PF02553 Cobalt transport protein component CbiN 12 77 1.6E-22 T 23-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 Mlab_1558 ca868817e7ab985c802458f57baa84eb 281 ProDom PD013899 METHYLTRANSFERASE C SUBUNIT M TETRAHYDROMETHANOPTERIN MEMBRANE S-METHYLTRANSFERASE N5-METHYLTETRAHYDROMETHANOPTERIN--COENZYME METHANOGENESIS TRANSFERASE 8 267 2.0E-47 T 23-10-2018 IPR005865 Tetrahydromethanopterin S-methyltransferase, subunit C GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1558 ca868817e7ab985c802458f57baa84eb 281 TIGRFAM TIGR01148 mtrC: tetrahydromethanopterin S-methyltransferase, subunit C 9 273 1.4E-62 T 23-10-2018 IPR005865 Tetrahydromethanopterin S-methyltransferase, subunit C GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1558 ca868817e7ab985c802458f57baa84eb 281 Hamap MF_01096 Tetrahydromethanopterin S-methyltransferase subunit C [mtrC]. 1 281 119.622 T 23-10-2018 IPR005865 Tetrahydromethanopterin S-methyltransferase, subunit C GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1558 ca868817e7ab985c802458f57baa84eb 281 Pfam PF04211 Tetrahydromethanopterin S-methyltransferase, subunit C 7 269 1.4E-67 T 23-10-2018 IPR005865 Tetrahydromethanopterin S-methyltransferase, subunit C GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1558 ca868817e7ab985c802458f57baa84eb 281 PIRSF PIRSF006530 1 281 2.8E-60 T 23-10-2018 IPR005865 Tetrahydromethanopterin S-methyltransferase, subunit C GO:0015948|GO:0016021|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_0556 8a60aba6ecb4dd9da8a585db42674364 274 Pfam PF00702 haloacid dehalogenase-like hydrolase 5 232 1.6E-16 T 23-10-2018 Mlab_0556 8a60aba6ecb4dd9da8a585db42674364 274 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 126 235 2.2E-19 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_0556 8a60aba6ecb4dd9da8a585db42674364 274 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 163 173 1.3E-6 T 23-10-2018 Mlab_0556 8a60aba6ecb4dd9da8a585db42674364 274 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 218 237 1.3E-6 T 23-10-2018 Mlab_0556 8a60aba6ecb4dd9da8a585db42674364 274 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 6 20 1.3E-6 T 23-10-2018 Mlab_0556 8a60aba6ecb4dd9da8a585db42674364 274 Gene3D G3DSA:3.40.50.1000 120 266 2.1E-26 T 23-10-2018 IPR023214 HAD superfamily Mlab_0556 8a60aba6ecb4dd9da8a585db42674364 274 SUPERFAMILY SSF56784 5 260 1.82E-27 T 23-10-2018 IPR036412 HAD-like superfamily Mlab_0076 a572eeba2df39a1701bf833b14fb1ef9 327 Pfam PF00296 Luciferase-like monooxygenase 12 305 2.1E-49 T 23-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Mlab_0076 a572eeba2df39a1701bf833b14fb1ef9 327 TIGRFAM TIGR03555 F420_mer: 5,10-methylenetetrahydromethanopterin reductase 3 325 2.8E-112 T 23-10-2018 IPR019946 5,10-methylenetetrahydromethanopterin reductase GO:0018537|GO:0055114 KEGG: 00680+1.5.98.2|MetaCyc: PWY-7784 Mlab_0076 a572eeba2df39a1701bf833b14fb1ef9 327 Hamap MF_01091 5,10-methylenetetrahydromethanopterin reductase [mer]. 1 327 179.281 T 23-10-2018 IPR019946 5,10-methylenetetrahydromethanopterin reductase GO:0018537|GO:0055114 KEGG: 00680+1.5.98.2|MetaCyc: PWY-7784 Mlab_0076 a572eeba2df39a1701bf833b14fb1ef9 327 Gene3D G3DSA:3.20.20.30 1 327 5.6E-84 T 23-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 Mlab_0076 a572eeba2df39a1701bf833b14fb1ef9 327 SUPERFAMILY SSF51679 1 325 1.7E-57 T 23-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 Mlab_1506 c0fa3e733b4a939243f993003969562e 490 Gene3D G3DSA:2.40.340.10 313 388 5.5E-7 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1506 c0fa3e733b4a939243f993003969562e 490 Gene3D G3DSA:3.40.980.10 165 305 2.4E-74 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily Mlab_1506 c0fa3e733b4a939243f993003969562e 490 Gene3D G3DSA:2.170.190.11 51 132 2.4E-74 T 23-10-2018 Mlab_1506 c0fa3e733b4a939243f993003969562e 490 Gene3D G3DSA:3.90.105.10 29 164 2.4E-74 T 23-10-2018 Mlab_1506 c0fa3e733b4a939243f993003969562e 490 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 169 301 1.3E-26 T 23-10-2018 IPR001453 MoaB/Mog domain Mlab_1506 c0fa3e733b4a939243f993003969562e 490 SUPERFAMILY SSF53218 169 306 7.98E-36 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily Mlab_1506 c0fa3e733b4a939243f993003969562e 490 SUPERFAMILY SSF63867 317 388 1.47E-8 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1506 c0fa3e733b4a939243f993003969562e 490 SUPERFAMILY SSF63882 8 166 3.14E-35 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1506 c0fa3e733b4a939243f993003969562e 490 SMART SM00852 170 307 8.0E-33 T 23-10-2018 IPR001453 MoaB/Mog domain Mlab_1506 c0fa3e733b4a939243f993003969562e 490 Pfam PF00994 Probable molybdopterin binding domain 170 305 6.3E-22 T 23-10-2018 IPR001453 MoaB/Mog domain Mlab_1506 c0fa3e733b4a939243f993003969562e 490 Pfam PF03454 MoeA C-terminal region (domain IV) 320 387 7.1E-6 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1506 c0fa3e733b4a939243f993003969562e 490 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 158 4.0E-31 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_0430 084bf6f583bb008ce3f82abfcf0c87cd 59 Gene3D G3DSA:3.30.70.20 1 27 9.9E-6 T 23-10-2018 Mlab_0430 084bf6f583bb008ce3f82abfcf0c87cd 59 Gene3D G3DSA:3.30.70.20 28 59 3.4E-5 T 23-10-2018 Mlab_0430 084bf6f583bb008ce3f82abfcf0c87cd 59 SUPERFAMILY SSF54862 1 59 5.73E-15 T 23-10-2018 Mlab_0430 084bf6f583bb008ce3f82abfcf0c87cd 59 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0430 084bf6f583bb008ce3f82abfcf0c87cd 59 Pfam PF00037 4Fe-4S binding domain 3 25 1.2E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_1128 dc405499e2dbd5915f898a5bc832a880 351 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 351 51.01 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Mlab_1128 dc405499e2dbd5915f898a5bc832a880 351 Pfam PF00155 Aminotransferase class I and II 31 347 1.5E-42 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Mlab_1128 dc405499e2dbd5915f898a5bc832a880 351 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 21 350 1.4E-84 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Mlab_1128 dc405499e2dbd5915f898a5bc832a880 351 SUPERFAMILY SSF53383 26 350 1.05E-67 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_1128 dc405499e2dbd5915f898a5bc832a880 351 Gene3D G3DSA:3.90.1150.10 31 342 9.0E-86 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_1128 dc405499e2dbd5915f898a5bc832a880 351 Gene3D G3DSA:3.40.640.10 44 261 9.0E-86 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_0953 2e81dfad64b39b12485c893779c34087 177 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 6 141 2.5E-25 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein Mlab_0646 d1a1535be8389d724dd7a51b7ac6ee12 278 Gene3D G3DSA:2.160.10.10 5 124 3.1E-8 T 23-10-2018 Mlab_0646 d1a1535be8389d724dd7a51b7ac6ee12 278 Pfam PF04519 Polymer-forming cytoskeletal 183 247 4.7E-7 T 23-10-2018 IPR007607 Bactofilin A/B Mlab_0646 d1a1535be8389d724dd7a51b7ac6ee12 278 Gene3D G3DSA:2.160.10.10 194 276 1.2E-5 T 23-10-2018 Mlab_0646 d1a1535be8389d724dd7a51b7ac6ee12 278 SUPERFAMILY SSF51161 67 263 1.25E-12 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily Mlab_1318 69dbb7cfdae8fde68f70e54a14f61b63 151 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 101 3.7E-22 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain Mlab_1318 69dbb7cfdae8fde68f70e54a14f61b63 151 Gene3D G3DSA:3.40.140.10 1 149 1.1E-44 T 23-10-2018 Mlab_1318 69dbb7cfdae8fde68f70e54a14f61b63 151 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 90 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Mlab_1318 69dbb7cfdae8fde68f70e54a14f61b63 151 SUPERFAMILY SSF53927 3 147 8.2E-41 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Mlab_1174 08fda336e2a3e1283263e7c013ed0f80 422 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 43 405 1.4E-156 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_1174 08fda336e2a3e1283263e7c013ed0f80 422 ProSitePatterns PS00674 AAA-protein family signature. 304 322 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Mlab_1174 08fda336e2a3e1283263e7c013ed0f80 422 SMART SM00382 196 336 2.2E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1174 08fda336e2a3e1283263e7c013ed0f80 422 Gene3D G3DSA:2.40.50.140 54 152 8.1E-21 T 23-10-2018 Mlab_1174 08fda336e2a3e1283263e7c013ed0f80 422 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 17 421 41.735 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN Mlab_1174 08fda336e2a3e1283263e7c013ed0f80 422 SUPERFAMILY SSF52540 158 412 1.19E-66 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1174 08fda336e2a3e1283263e7c013ed0f80 422 Gene3D G3DSA:3.40.50.300 153 334 2.2E-65 T 23-10-2018 Mlab_1174 08fda336e2a3e1283263e7c013ed0f80 422 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 200 334 1.2E-42 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_1174 08fda336e2a3e1283263e7c013ed0f80 422 Gene3D G3DSA:1.10.8.60 335 405 4.5E-22 T 23-10-2018 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 SUPERFAMILY SSF54826 4 125 3.76E-35 T 23-10-2018 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 PIRSF PIRSF001400 1 399 2.5E-141 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 Pfam PF03952 Enolase, N-terminal domain 4 123 3.4E-32 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 398 1.3E-136 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 ProSitePatterns PS00164 Enolase signature. 323 336 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 SMART SM01193 4 123 8.5E-48 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 SUPERFAMILY SSF51604 131 398 7.47E-90 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 Gene3D G3DSA:3.30.390.10 1 115 1.8E-29 T 23-10-2018 IPR029017 Enolase-like, N-terminal Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 Hamap MF_00318 Enolase [eno]. 2 399 38.273 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 PRINTS PR00148 Enolase signature 323 337 3.3E-35 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 PRINTS PR00148 Enolase signature 96 112 3.3E-35 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 PRINTS PR00148 Enolase signature 150 163 3.3E-35 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 PRINTS PR00148 Enolase signature 352 369 3.3E-35 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 PRINTS PR00148 Enolase signature 300 311 3.3E-35 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 PRINTS PR00148 Enolase signature 37 51 3.3E-35 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 SMART SM01192 128 399 2.0E-116 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 Pfam PF00113 Enolase, C-terminal TIM barrel domain 132 398 7.2E-72 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Mlab_1238 fe84cb91e3a9393e549d9daaecb6dab4 399 Gene3D G3DSA:3.20.20.120 117 399 4.5E-93 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Mlab_1103 bf4b65168ec4c2f98bacb2a6c3652d7a 148 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 66 140 4.9E-28 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Mlab_1103 bf4b65168ec4c2f98bacb2a6c3652d7a 148 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 110 116 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 Mlab_1103 bf4b65168ec4c2f98bacb2a6c3652d7a 148 Gene3D G3DSA:1.10.10.10 65 144 7.2E-29 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1103 bf4b65168ec4c2f98bacb2a6c3652d7a 148 SUPERFAMILY SSF46767 62 140 1.03E-25 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 Mlab_1103 bf4b65168ec4c2f98bacb2a6c3652d7a 148 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 67 139 2.6E-25 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Mlab_1243 d0a4b01747b3b2c6075468e905941ca0 117 Gene3D G3DSA:3.100.10.10 1 117 6.4E-38 T 23-10-2018 Mlab_1243 d0a4b01747b3b2c6075468e905941ca0 117 SUPERFAMILY SSF52080 3 117 3.79E-26 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily Mlab_1243 d0a4b01747b3b2c6075468e905941ca0 117 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 1 116 25.61 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea Mlab_1243 d0a4b01747b3b2c6075468e905941ca0 117 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 4 117 3.5E-13 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P Mlab_0834 24d810d3beec62d5b9b5eebd5baf325f 319 SUPERFAMILY SSF52402 71 299 1.98E-44 T 23-10-2018 Mlab_0834 24d810d3beec62d5b9b5eebd5baf325f 319 Gene3D G3DSA:3.40.50.620 69 317 1.2E-54 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0834 24d810d3beec62d5b9b5eebd5baf325f 319 Pfam PF00733 Asparagine synthase 227 292 6.1E-9 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 Mlab_0834 24d810d3beec62d5b9b5eebd5baf325f 319 Pfam PF00733 Asparagine synthase 71 217 8.0E-23 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 Mlab_1642 c3434b3af10ff5f6f19a452d38ae3f00 521 Pfam PF17200 Single Cache domain 2 279 382 1.6E-18 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_1642 c3434b3af10ff5f6f19a452d38ae3f00 521 Pfam PF17200 Single Cache domain 2 417 505 1.7E-6 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_1642 c3434b3af10ff5f6f19a452d38ae3f00 521 SMART SM01049 396 473 1.4 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_1642 c3434b3af10ff5f6f19a452d38ae3f00 521 SMART SM01049 251 332 3.2E-14 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_1642 c3434b3af10ff5f6f19a452d38ae3f00 521 Gene3D G3DSA:3.30.450.20 251 389 1.9E-31 T 23-10-2018 Mlab_1642 c3434b3af10ff5f6f19a452d38ae3f00 521 Gene3D G3DSA:3.30.450.20 414 517 3.4E-11 T 23-10-2018 Mlab_0970 200dceb6c72a4b440baba9d627deb14f 300 Pfam PF01171 PP-loop family 52 191 1.9E-11 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 Mlab_0970 200dceb6c72a4b440baba9d627deb14f 300 SUPERFAMILY SSF52402 39 262 4.85E-45 T 23-10-2018 Mlab_0970 200dceb6c72a4b440baba9d627deb14f 300 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 196 299 5.2E-23 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 Mlab_0970 200dceb6c72a4b440baba9d627deb14f 300 Gene3D G3DSA:3.40.50.620 4 300 1.2E-71 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0970 200dceb6c72a4b440baba9d627deb14f 300 PIRSF PIRSF004976 1 300 2.9E-88 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 Mlab_1717 6c80ada958dcab020041b260abd8f473 2772 SUPERFAMILY SSF56524 2064 2169 3.66E-10 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Mlab_1717 6c80ada958dcab020041b260abd8f473 2772 SUPERFAMILY SSF56524 1657 1794 8.24E-8 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 SMART SM00863 121 170 3.0E-15 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 Gene3D G3DSA:3.40.50.800 482 586 5.3E-30 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 Pfam PF03129 Anticodon binding domain 491 579 3.4E-18 T 23-10-2018 IPR004154 Anticodon-binding Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 Gene3D G3DSA:3.30.54.20 82 138 1.7E-55 T 23-10-2018 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 17 584 32.772 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 275 478 8.6E-40 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 23 581 1.9E-207 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 PRINTS PR01047 Threonyl-tRNA synthetase signature 313 336 1.5E-49 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 PRINTS PR01047 Threonyl-tRNA synthetase signature 457 470 1.5E-49 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 PRINTS PR01047 Threonyl-tRNA synthetase signature 414 442 1.5E-49 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 PRINTS PR01047 Threonyl-tRNA synthetase signature 484 496 1.5E-49 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 PRINTS PR01047 Threonyl-tRNA synthetase signature 280 308 1.5E-49 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 125 169 6.9E-10 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 SUPERFAMILY SSF52954 480 584 2.42E-28 T 23-10-2018 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 SUPERFAMILY SSF55681 194 475 6.89E-96 T 23-10-2018 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 SUPERFAMILY SSF55186 16 192 4.32E-54 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 Gene3D G3DSA:3.30.930.10 174 481 2.9E-128 T 23-10-2018 Mlab_1319 db2a12d42188d997e65b5b86491874b6 586 Gene3D G3DSA:3.30.980.10 20 173 1.7E-55 T 23-10-2018 Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 967 1229 1.9E-86 T 23-10-2018 Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 SMART SM01211 966 1229 1.7E-113 T 23-10-2018 Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 Gene3D G3DSA:3.40.50.880 942 1229 1.2E-79 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 SUPERFAMILY SSF55326 196 421 2.89E-32 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 SUPERFAMILY SSF55326 622 799 4.54E-36 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 TIGRFAM TIGR01857 FGAM-synthase: phosphoribosylformylglycinamidine synthase 4 1229 0.0 T 23-10-2018 IPR010141 Phosphoribosylformylglycinamidine synthase, FGAM Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 SUPERFAMILY SSF56042 431 600 8.02E-39 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 Gene3D G3DSA:3.30.1330.10 634 795 2.7E-31 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 Gene3D G3DSA:3.90.650.10 800 935 8.4E-6 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 SUPERFAMILY SSF56042 802 936 5.23E-10 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 SUPERFAMILY SSF52317 964 1229 1.06E-71 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 Gene3D G3DSA:3.90.650.10 420 598 4.0E-46 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Mlab_0300 58225326aa64cacf084cc9667be6f39c 1231 Pfam PF02769 AIR synthase related protein, C-terminal domain 431 580 2.6E-22 T 23-10-2018 IPR010918 PurM-like, C-terminal domain Mlab_1694 c8b2c69e1cbfbd62e081f2f49b115347 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 6.0E-9 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Mlab_1694 c8b2c69e1cbfbd62e081f2f49b115347 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 6.0E-9 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Mlab_1694 c8b2c69e1cbfbd62e081f2f49b115347 219 SUPERFAMILY SSF46689 9 81 4.17E-18 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Mlab_1694 c8b2c69e1cbfbd62e081f2f49b115347 219 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 65 - T 23-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Mlab_1694 c8b2c69e1cbfbd62e081f2f49b115347 219 Gene3D G3DSA:1.10.357.10 10 199 6.4E-30 T 23-10-2018 Mlab_1694 c8b2c69e1cbfbd62e081f2f49b115347 219 SUPERFAMILY SSF48498 90 197 1.57E-15 T 23-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Mlab_1694 c8b2c69e1cbfbd62e081f2f49b115347 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 2.4E-16 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Mlab_0580 6e3683d86989ed25608fcf8be2030604 416 Pfam PF04055 Radical SAM superfamily 131 301 6.6E-21 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0580 6e3683d86989ed25608fcf8be2030604 416 SMART SM00729 125 344 3.6E-53 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_0580 6e3683d86989ed25608fcf8be2030604 416 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 127 413 2.0E-94 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 Mlab_0580 6e3683d86989ed25608fcf8be2030604 416 Gene3D G3DSA:3.40.50.12160 15 125 4.5E-17 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Mlab_0580 6e3683d86989ed25608fcf8be2030604 416 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 129 149 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Mlab_0580 6e3683d86989ed25608fcf8be2030604 416 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 124 411 2.3E-80 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Mlab_0580 6e3683d86989ed25608fcf8be2030604 416 SUPERFAMILY SSF102114 97 348 2.09E-52 T 23-10-2018 Mlab_0580 6e3683d86989ed25608fcf8be2030604 416 Pfam PF00919 Uncharacterized protein family UPF0004 18 104 2.1E-16 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Mlab_0580 6e3683d86989ed25608fcf8be2030604 416 Gene3D G3DSA:3.80.30.20 126 358 7.9E-72 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Mlab_0682 56f620cea11476e80c299006d4fac454 251 Gene3D G3DSA:3.40.1160.10 2 250 4.6E-60 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_0682 56f620cea11476e80c299006d4fac454 251 PIRSF PIRSF016496 1 251 4.0E-76 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 Mlab_0682 56f620cea11476e80c299006d4fac454 251 SUPERFAMILY SSF53633 3 250 3.01E-35 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_0682 56f620cea11476e80c299006d4fac454 251 Pfam PF00696 Amino acid kinase family 4 230 1.7E-44 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 Pfam PF03129 Anticodon binding domain 473 561 4.0E-19 T 23-10-2018 IPR004154 Anticodon-binding Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 Gene3D G3DSA:3.30.930.10 7 122 9.0E-26 T 23-10-2018 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 Gene3D G3DSA:3.40.50.800 471 575 7.9E-33 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 159 227 1.1E-8 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 SUPERFAMILY SSF55681 7 476 8.11E-106 T 23-10-2018 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 8 561 8.2E-205 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 PRINTS PR01043 Glycyl-tRNA synthetase signature 143 155 6.5E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 PRINTS PR01043 Glycyl-tRNA synthetase signature 211 221 6.5E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 PRINTS PR01043 Glycyl-tRNA synthetase signature 429 441 6.5E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 6.5E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 PRINTS PR01043 Glycyl-tRNA synthetase signature 162 179 6.5E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 PRINTS PR01043 Glycyl-tRNA synthetase signature 511 530 6.5E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 PRINTS PR01043 Glycyl-tRNA synthetase signature 194 211 6.5E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Mlab_1156 aeae1fb2a1dc17779ef46db46de216c0 576 SUPERFAMILY SSF52954 460 569 7.1E-30 T 23-10-2018 Mlab_1321 25388bf1acfad566cad8c3fa9a315849 915 Pfam PF12705 PD-(D/E)XK nuclease superfamily 639 906 3.5E-33 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type Mlab_1321 25388bf1acfad566cad8c3fa9a315849 915 Gene3D G3DSA:3.90.320.10 656 838 7.0E-8 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal Mlab_1321 25388bf1acfad566cad8c3fa9a315849 915 SUPERFAMILY SSF52980 647 831 9.12E-7 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Mlab_1321 25388bf1acfad566cad8c3fa9a315849 915 Gene3D G3DSA:3.40.50.300 424 559 7.4E-8 T 23-10-2018 Mlab_1321 25388bf1acfad566cad8c3fa9a315849 915 SUPERFAMILY SSF52540 205 554 4.04E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0432 fe888c9834080f37021a1f4918dad4fc 265 Pfam PF13187 4Fe-4S dicluster domain 15 61 1.6E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0432 fe888c9834080f37021a1f4918dad4fc 265 Gene3D G3DSA:3.40.109.10 77 254 1.4E-29 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Mlab_0432 fe888c9834080f37021a1f4918dad4fc 265 SUPERFAMILY SSF55469 81 264 2.75E-33 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Mlab_0432 fe888c9834080f37021a1f4918dad4fc 265 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0432 fe888c9834080f37021a1f4918dad4fc 265 SUPERFAMILY SSF54862 7 80 1.47E-18 T 23-10-2018 Mlab_0432 fe888c9834080f37021a1f4918dad4fc 265 Pfam PF00881 Nitroreductase family 82 246 1.8E-21 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Mlab_0432 fe888c9834080f37021a1f4918dad4fc 265 Gene3D G3DSA:3.30.70.20 3 71 1.8E-11 T 23-10-2018 Mlab_1696 b0c0baf76a16396677ddd23a7dbec6a4 298 Pfam PF04072 Leucine carboxyl methyltransferase 16 200 2.0E-55 T 23-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 Mlab_1696 b0c0baf76a16396677ddd23a7dbec6a4 298 SUPERFAMILY SSF53335 12 295 3.65E-65 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1696 b0c0baf76a16396677ddd23a7dbec6a4 298 Gene3D G3DSA:3.40.50.150 3 276 5.4E-61 T 23-10-2018 Mlab_1696 b0c0baf76a16396677ddd23a7dbec6a4 298 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 13 264 3.5E-63 T 23-10-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 Mlab_0554 6a591b5e05185792172235cab6f52c27 514 PIRSF PIRSF005852 4 514 1.8E-109 T 23-10-2018 IPR016466 Uncharacterised protein family UPF0288, methanogenesis Mlab_0554 6a591b5e05185792172235cab6f52c27 514 Hamap MF_01089 UPF0288 protein . 4 513 26.68 T 23-10-2018 IPR016466 Uncharacterised protein family UPF0288, methanogenesis Mlab_0554 6a591b5e05185792172235cab6f52c27 514 TIGRFAM TIGR03268 methan_mark_3: putative methanogenesis marker protein 3 6 511 8.6E-132 T 23-10-2018 IPR016466 Uncharacterised protein family UPF0288, methanogenesis Mlab_1015 9bb47c56338fffe14bdc238b2ef57678 212 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 15 62 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_1015 9bb47c56338fffe14bdc238b2ef57678 212 SUPERFAMILY SSF56235 6 208 6.72E-68 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Mlab_1015 9bb47c56338fffe14bdc238b2ef57678 212 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 11 195 4.5E-76 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 Mlab_1015 9bb47c56338fffe14bdc238b2ef57678 212 Pfam PF00227 Proteasome subunit 8 191 1.2E-59 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_1015 9bb47c56338fffe14bdc238b2ef57678 212 Hamap MF_02113_A Proteasome subunit beta [prcB]. 7 203 36.121 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 Mlab_1015 9bb47c56338fffe14bdc238b2ef57678 212 PRINTS PR00141 Proteasome component signature 141 152 3.0E-12 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_1015 9bb47c56338fffe14bdc238b2ef57678 212 PRINTS PR00141 Proteasome component signature 177 188 3.0E-12 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_1015 9bb47c56338fffe14bdc238b2ef57678 212 PRINTS PR00141 Proteasome component signature 152 163 3.0E-12 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_1015 9bb47c56338fffe14bdc238b2ef57678 212 PRINTS PR00141 Proteasome component signature 19 34 3.0E-12 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_1015 9bb47c56338fffe14bdc238b2ef57678 212 Gene3D G3DSA:3.60.20.10 1 209 5.3E-74 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Mlab_0818 73a86faf1059da37186d2b79181f725f 352 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 9 339 1.9E-114 T 23-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Mlab_0818 73a86faf1059da37186d2b79181f725f 352 Pfam PF01758 Sodium Bile acid symporter family 54 251 1.9E-46 T 23-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 Mlab_0818 73a86faf1059da37186d2b79181f725f 352 Gene3D G3DSA:1.20.1530.20 5 340 2.8E-26 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily Mlab_0818 73a86faf1059da37186d2b79181f725f 352 PIRSF PIRSF005508 1 351 1.2E-127 T 23-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Mlab_1668 49512b52bd3bad568aa00a9170884759 323 SUPERFAMILY SSF53067 16 319 6.49E-47 T 23-10-2018 Mlab_1668 49512b52bd3bad568aa00a9170884759 323 Gene3D G3DSA:3.30.420.40 19 310 2.5E-64 T 23-10-2018 Mlab_1668 49512b52bd3bad568aa00a9170884759 323 Pfam PF00480 ROK family 18 311 9.6E-47 T 23-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Mlab_1668 49512b52bd3bad568aa00a9170884759 323 Gene3D G3DSA:3.30.420.40 139 298 2.5E-64 T 23-10-2018 Mlab_1733 092d0f3cb5074fbd0e27c5710c03482d 286 Gene3D G3DSA:1.10.10.10 199 264 3.7E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1733 092d0f3cb5074fbd0e27c5710c03482d 286 SUPERFAMILY SSF46785 197 270 3.72E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 Pfam PF05746 DALR anticodon binding domain 444 558 4.9E-31 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 SMART SM01016 7 82 5.4E-12 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 SUPERFAMILY SSF55190 20 92 1.7E-11 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 SUPERFAMILY SSF52374 103 437 3.01E-76 T 23-10-2018 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 118 127 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 Gene3D G3DSA:1.10.730.10 444 558 5.5E-31 T 23-10-2018 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 PRINTS PR01038 Arginyl-tRNA synthetase signature 108 123 2.4E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 PRINTS PR01038 Arginyl-tRNA synthetase signature 147 160 2.4E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 PRINTS PR01038 Arginyl-tRNA synthetase signature 294 315 2.4E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 PRINTS PR01038 Arginyl-tRNA synthetase signature 123 139 2.4E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 Gene3D G3DSA:3.40.50.620 105 443 4.0E-93 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 SMART SM00836 444 558 2.2E-36 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 Hamap MF_00123 Arginine--tRNA ligase [argS]. 4 558 25.071 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 Pfam PF00750 tRNA synthetases class I (R) 104 430 3.2E-33 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 SUPERFAMILY SSF47323 440 558 1.63E-33 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 25 558 3.7E-153 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 3 81 2.3E-9 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_1508 1d8f110213e156550e2b74aa7e6e72e6 558 Gene3D G3DSA:3.30.1360.70 2 103 9.1E-12 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 Mlab_0851 5f6c1857a13c8b6327391a4559fdb875 224 Gene3D G3DSA:3.90.320.10 7 199 1.1E-6 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal Mlab_0851 5f6c1857a13c8b6327391a4559fdb875 224 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 10 198 7.6E-41 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 Mlab_0851 5f6c1857a13c8b6327391a4559fdb875 224 Pfam PF01930 Domain of unknown function DUF83 9 198 1.7E-33 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 Mlab_0531 ddbde33755d84a97f9e5653be8e82b73 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 223 234 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0531 ddbde33755d84a97f9e5653be8e82b73 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0531 ddbde33755d84a97f9e5653be8e82b73 367 Gene3D G3DSA:3.30.70.20 188 265 1.4E-13 T 23-10-2018 Mlab_0531 ddbde33755d84a97f9e5653be8e82b73 367 Pfam PF04015 Domain of unknown function (DUF362) 42 312 1.4E-40 T 23-10-2018 IPR007160 Domain of unknown function DUF362 Mlab_0531 ddbde33755d84a97f9e5653be8e82b73 367 Pfam PF00037 4Fe-4S binding domain 217 238 2.2E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0531 ddbde33755d84a97f9e5653be8e82b73 367 Pfam PF00037 4Fe-4S binding domain 189 209 3.1E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0531 ddbde33755d84a97f9e5653be8e82b73 367 SUPERFAMILY SSF54862 144 302 1.2E-27 T 23-10-2018 Mlab_1638 1cf7b700166bbbd94955f1cc5eafa93f 290 SUPERFAMILY SSF101478 18 278 2.75E-36 T 23-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily Mlab_1638 1cf7b700166bbbd94955f1cc5eafa93f 290 Pfam PF03747 ADP-ribosylglycohydrolase 21 258 2.2E-34 T 23-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 Mlab_1638 1cf7b700166bbbd94955f1cc5eafa93f 290 Gene3D G3DSA:1.10.4080.10 1 288 1.6E-37 T 23-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily Mlab_1356 b76fbb58382956c305804fe02021f952 416 Gene3D G3DSA:3.90.1150.10 7 390 3.3E-173 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_1356 b76fbb58382956c305804fe02021f952 416 PIRSF PIRSF000412 1 415 2.5E-157 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Mlab_1356 b76fbb58382956c305804fe02021f952 416 Gene3D G3DSA:3.40.640.10 33 283 3.3E-173 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_1356 b76fbb58382956c305804fe02021f952 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 49.268 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Mlab_1356 b76fbb58382956c305804fe02021f952 416 Pfam PF00464 Serine hydroxymethyltransferase 6 380 5.4E-155 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Mlab_1356 b76fbb58382956c305804fe02021f952 416 SUPERFAMILY SSF53383 2 411 6.05E-168 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_1700 96d4de9c5b829746d8843c90dc53e867 158 Pfam PF13646 HEAT repeats 95 150 3.9E-7 T 23-10-2018 Mlab_1700 96d4de9c5b829746d8843c90dc53e867 158 SMART SM00567 E-Z type HEAT repeats 49 77 650.0 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Mlab_1700 96d4de9c5b829746d8843c90dc53e867 158 SMART SM00567 E-Z type HEAT repeats 110 138 0.59 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Mlab_1700 96d4de9c5b829746d8843c90dc53e867 158 SMART SM00567 E-Z type HEAT repeats 15 47 83.0 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Mlab_1700 96d4de9c5b829746d8843c90dc53e867 158 SUPERFAMILY SSF48371 7 152 4.99E-16 T 23-10-2018 IPR016024 Armadillo-type fold Mlab_1700 96d4de9c5b829746d8843c90dc53e867 158 Gene3D G3DSA:1.25.10.10 2 156 1.5E-18 T 23-10-2018 IPR011989 Armadillo-like helical Mlab_0091 c99229bc8f86e9afbddebbbdecacc814 132 Pfam PF00238 Ribosomal protein L14p/L23e 12 131 1.1E-34 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Mlab_0091 c99229bc8f86e9afbddebbbdecacc814 132 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 11 132 19.443 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Mlab_0091 c99229bc8f86e9afbddebbbdecacc814 132 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 2 132 9.8E-61 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal Mlab_0091 c99229bc8f86e9afbddebbbdecacc814 132 SMART SM01374 11 132 1.6E-57 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Mlab_0091 c99229bc8f86e9afbddebbbdecacc814 132 Gene3D G3DSA:2.40.150.20 1 132 6.0E-49 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 Mlab_0091 c99229bc8f86e9afbddebbbdecacc814 132 SUPERFAMILY SSF50193 1 132 1.96E-42 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 1 429 42.269 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 15 429 1.1E-187 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 384 398 4.2E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 183 195 4.2E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 344 360 4.2E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 200 213 4.2E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 Gene3D G3DSA:2.40.50.140 13 99 4.4E-21 T 23-10-2018 Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 SUPERFAMILY SSF50249 16 101 1.84E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 Gene3D G3DSA:3.30.930.10 103 429 2.3E-105 T 23-10-2018 Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 SUPERFAMILY SSF55681 113 424 1.91E-93 T 23-10-2018 Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 Pfam PF00152 tRNA synthetases class II (D, K and N) 114 423 2.1E-88 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0039 17520b49d270f3664c2ad9b5e6f2256f 429 Pfam PF01336 OB-fold nucleic acid binding domain 16 87 4.5E-10 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Mlab_0145 ef10a68c0de563942a5d195ad793cb26 467 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 114 260 3.5E-5 T 23-10-2018 IPR015324 Ribosomal protein Rsm22-like GO:0006412|GO:0008168 Mlab_0145 ef10a68c0de563942a5d195ad793cb26 467 SUPERFAMILY SSF53335 95 238 5.42E-11 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0145 ef10a68c0de563942a5d195ad793cb26 467 Gene3D G3DSA:3.40.50.150 56 268 4.1E-10 T 23-10-2018 Mlab_1368 11294ef1634df6e3a6f1eb56a23cce4a 336 SUPERFAMILY SSF55267 2 63 3.53E-8 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 Mlab_1368 11294ef1634df6e3a6f1eb56a23cce4a 336 SUPERFAMILY SSF53032 68 157 3.84E-20 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 Mlab_1368 11294ef1634df6e3a6f1eb56a23cce4a 336 TIGRFAM TIGR00324 endA: tRNA-intron lyase 208 332 3.0E-17 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 Mlab_1368 11294ef1634df6e3a6f1eb56a23cce4a 336 TIGRFAM TIGR00324 endA: tRNA-intron lyase 22 157 3.0E-18 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 Mlab_1368 11294ef1634df6e3a6f1eb56a23cce4a 336 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 70 153 3.5E-18 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 Mlab_1368 11294ef1634df6e3a6f1eb56a23cce4a 336 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 247 323 5.7E-23 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 Mlab_1368 11294ef1634df6e3a6f1eb56a23cce4a 336 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 1 60 4.5E-13 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 Mlab_1368 11294ef1634df6e3a6f1eb56a23cce4a 336 Gene3D G3DSA:3.40.1350.150 17 160 2.6E-35 T 23-10-2018 Mlab_1368 11294ef1634df6e3a6f1eb56a23cce4a 336 SUPERFAMILY SSF53032 246 323 9.77E-20 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 Mlab_1368 11294ef1634df6e3a6f1eb56a23cce4a 336 Gene3D G3DSA:3.40.1350.10 246 336 3.0E-21 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 Mlab_1378 c674af3ee94016c56b6bf64411cc658c 409 Gene3D G3DSA:3.40.50.300 1 253 1.9E-68 T 23-10-2018 Mlab_1378 c674af3ee94016c56b6bf64411cc658c 409 SUPERFAMILY SSF52540 3 230 6.43E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1378 c674af3ee94016c56b6bf64411cc658c 409 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1378 c674af3ee94016c56b6bf64411cc658c 409 SMART SM00382 29 216 6.0E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1378 c674af3ee94016c56b6bf64411cc658c 409 Pfam PF00005 ABC transporter 21 169 1.7E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1378 c674af3ee94016c56b6bf64411cc658c 409 ProDom PD064925 ATP-BINDING ABC NUCLEOTIDE-BINDING MEMBRANE TRANSPORTER IRON TRANSPORTER COMPOUND ATPASE III 291 361 1.0E-10 T 23-10-2018 IPR020322 Uncharacterised domain MJ0874 Mlab_1160 d98c9e3a364c03cee4e815a2e9d0f902 504 Pfam PF04998 RNA polymerase Rpb1, domain 5 134 448 1.3E-50 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1160 d98c9e3a364c03cee4e815a2e9d0f902 504 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 144 498 1.5E-144 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1160 d98c9e3a364c03cee4e815a2e9d0f902 504 Gene3D G3DSA:1.10.150.390 449 494 6.6E-22 T 23-10-2018 Mlab_1160 d98c9e3a364c03cee4e815a2e9d0f902 504 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 96 501 38.864 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1160 d98c9e3a364c03cee4e815a2e9d0f902 504 SUPERFAMILY SSF64484 142 498 1.53E-94 T 23-10-2018 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 SUPERFAMILY SSF54975 3 86 6.98E-19 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 PIRSF PIRSF006256 1 741 1.9E-228 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 7 732 4.3E-214 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 Gene3D G3DSA:3.30.420.360 371 731 1.3E-99 T 23-10-2018 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 Pfam PF00708 Acylphosphatase 5 85 1.1E-18 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 SUPERFAMILY SSF53067 577 713 3.08E-5 T 23-10-2018 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 Gene3D G3DSA:3.30.420.350 473 719 1.3E-99 T 23-10-2018 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 SUPERFAMILY SSF55821 170 376 8.55E-28 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 Gene3D G3DSA:3.30.110.120 245 362 6.7E-120 T 23-10-2018 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 Pfam PF07503 HypF finger 154 186 1.8E-15 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 Pfam PF07503 HypF finger 103 136 2.4E-13 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 Gene3D G3DSA:3.90.870.50 6 353 6.7E-120 T 23-10-2018 Mlab_1577 440f0568b0f81a3f09a24b63e4b49b73 742 Pfam PF01300 Telomere recombination 204 363 1.1E-32 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 SUPERFAMILY SSF48452 4 78 9.05E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 SUPERFAMILY SSF48452 56 227 7.25E-30 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 Pfam PF13371 Tetratricopeptide repeat 168 238 2.7E-10 T 23-10-2018 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 SMART SM00028 92 125 12.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 SMART SM00028 24 57 1.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 SMART SM00028 160 193 2.9 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 SMART SM00028 58 91 96.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 SMART SM00028 194 227 2.6E-4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 SMART SM00028 126 159 53.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 Pfam PF13432 Tetratricopeptide repeat 97 145 5.2E-5 T 23-10-2018 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 Pfam PF13432 Tetratricopeptide repeat 63 92 0.0019 T 23-10-2018 Mlab_1454 d92241e499574e59761e9f92ccf15386 240 Gene3D G3DSA:1.25.40.10 1 238 5.0E-43 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0860 0e81cd2b02b5df54a49bf2a02ea0657c 285 PIRSF PIRSF006593 1 285 1.1E-67 T 23-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 Mlab_0860 0e81cd2b02b5df54a49bf2a02ea0657c 285 SUPERFAMILY SSF111321 1 283 1.83E-70 T 23-10-2018 IPR036075 AF1104-like superfamily Mlab_0860 0e81cd2b02b5df54a49bf2a02ea0657c 285 Gene3D G3DSA:1.10.285.20 69 134 2.8E-11 T 23-10-2018 Mlab_0860 0e81cd2b02b5df54a49bf2a02ea0657c 285 Gene3D G3DSA:1.10.8.380 7 68 2.1E-10 T 23-10-2018 Mlab_0860 0e81cd2b02b5df54a49bf2a02ea0657c 285 Gene3D G3DSA:3.40.50.10880 135 283 8.0E-41 T 23-10-2018 Mlab_0860 0e81cd2b02b5df54a49bf2a02ea0657c 285 Pfam PF01937 Protein of unknown function DUF89 4 278 3.8E-43 T 23-10-2018 IPR002791 Domain of unknown function DUF89 Mlab_0760 ab120998af8d66f8eb0e16d1e0d83171 120 ProSitePatterns PS00194 Thioredoxin family active site. 36 54 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Mlab_0760 ab120998af8d66f8eb0e16d1e0d83171 120 SUPERFAMILY SSF52833 16 117 1.37E-26 T 23-10-2018 IPR036249 Thioredoxin-like superfamily Mlab_0760 ab120998af8d66f8eb0e16d1e0d83171 120 PRINTS PR00421 Thioredoxin family signature 35 43 9.4E-5 T 23-10-2018 Mlab_0760 ab120998af8d66f8eb0e16d1e0d83171 120 PRINTS PR00421 Thioredoxin family signature 82 93 9.4E-5 T 23-10-2018 Mlab_0760 ab120998af8d66f8eb0e16d1e0d83171 120 PRINTS PR00421 Thioredoxin family signature 43 52 9.4E-5 T 23-10-2018 Mlab_0760 ab120998af8d66f8eb0e16d1e0d83171 120 PIRSF PIRSF000077 15 118 8.3E-21 T 23-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Mlab_0760 ab120998af8d66f8eb0e16d1e0d83171 120 Pfam PF00085 Thioredoxin 17 115 1.3E-19 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 Mlab_0760 ab120998af8d66f8eb0e16d1e0d83171 120 Gene3D G3DSA:3.40.30.10 13 118 4.4E-22 T 23-10-2018 Mlab_1235 5ab053dfd1d3922b9a8ecb2dd63faa0c 222 Gene3D G3DSA:3.40.50.10550 82 222 6.4E-65 T 23-10-2018 Mlab_1235 5ab053dfd1d3922b9a8ecb2dd63faa0c 222 Gene3D G3DSA:3.30.70.260 3 80 2.3E-11 T 23-10-2018 Mlab_1235 5ab053dfd1d3922b9a8ecb2dd63faa0c 222 SUPERFAMILY SSF52172 82 219 3.48E-61 T 23-10-2018 IPR011006 CheY-like superfamily Mlab_1235 5ab053dfd1d3922b9a8ecb2dd63faa0c 222 Pfam PF01842 ACT domain 6 40 9.6E-7 T 23-10-2018 IPR002912 ACT domain Mlab_1235 5ab053dfd1d3922b9a8ecb2dd63faa0c 222 PIRSF PIRSF006363 3 222 3.7E-83 T 23-10-2018 IPR015832 Uncharacterised conserved protein UCP006363, ACT-type Mlab_1235 5ab053dfd1d3922b9a8ecb2dd63faa0c 222 SUPERFAMILY SSF55021 5 79 1.94E-11 T 23-10-2018 Mlab_0176 f758f368c95ac168812ab1bee83ca7cc 547 SUPERFAMILY SSF56112 89 425 5.33E-26 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily Mlab_0176 f758f368c95ac168812ab1bee83ca7cc 547 Pfam PF03109 ABC1 family 110 226 7.5E-29 T 23-10-2018 IPR004147 UbiB domain Mlab_1218 c6d6088031c9bb9474b05f37f608fe8f 83 PRINTS PR00124 ATP synthase C subunit signature 18 37 4.6E-7 T 23-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Mlab_1218 c6d6088031c9bb9474b05f37f608fe8f 83 PRINTS PR00124 ATP synthase C subunit signature 56 81 4.6E-7 T 23-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Mlab_1218 c6d6088031c9bb9474b05f37f608fe8f 83 Gene3D G3DSA:1.20.120.610 1 83 3.2E-15 T 23-10-2018 Mlab_1218 c6d6088031c9bb9474b05f37f608fe8f 83 Pfam PF00137 ATP synthase subunit C 21 80 7.2E-14 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 Mlab_1218 c6d6088031c9bb9474b05f37f608fe8f 83 SUPERFAMILY SSF81333 14 82 4.18E-14 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily Mlab_0685 c07c2443a4e7d14fdd0749392adb240b 322 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 79 93 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site Mlab_0685 c07c2443a4e7d14fdd0749392adb240b 322 SUPERFAMILY SSF48576 6 321 8.11E-83 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily Mlab_0685 c07c2443a4e7d14fdd0749392adb240b 322 Gene3D G3DSA:1.10.600.10 1 322 8.0E-93 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily Mlab_0685 c07c2443a4e7d14fdd0749392adb240b 322 Pfam PF00348 Polyprenyl synthetase 28 249 3.2E-64 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 Mlab_1310 5180a822c52c660fbae113a0f86ec64f 392 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 332 363 2.7E-5 T 23-10-2018 IPR001451 Hexapeptide repeat Mlab_1310 5180a822c52c660fbae113a0f86ec64f 392 Pfam PF00483 Nucleotidyl transferase 2 230 3.3E-44 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Mlab_1310 5180a822c52c660fbae113a0f86ec64f 392 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 273 303 2.6E-6 T 23-10-2018 IPR001451 Hexapeptide repeat Mlab_1310 5180a822c52c660fbae113a0f86ec64f 392 Gene3D G3DSA:3.90.550.10 1 236 7.0E-65 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1310 5180a822c52c660fbae113a0f86ec64f 392 Gene3D G3DSA:2.160.10.10 310 381 2.3E-9 T 23-10-2018 Mlab_1310 5180a822c52c660fbae113a0f86ec64f 392 Gene3D G3DSA:2.160.10.10 237 309 4.3E-11 T 23-10-2018 Mlab_1310 5180a822c52c660fbae113a0f86ec64f 392 SUPERFAMILY SSF51161 187 376 3.9E-33 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily Mlab_1310 5180a822c52c660fbae113a0f86ec64f 392 SUPERFAMILY SSF53448 1 298 1.96E-72 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1163 7e58afaaa4d3f51a17fd6d06eabab042 516 Gene3D G3DSA:3.90.1110.10 171 346 5.2E-32 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1163 7e58afaaa4d3f51a17fd6d06eabab042 516 Pfam PF04561 RNA polymerase Rpb2, domain 2 170 360 5.0E-17 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1163 7e58afaaa4d3f51a17fd6d06eabab042 516 Pfam PF04565 RNA polymerase Rpb2, domain 3 428 492 5.8E-26 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1163 7e58afaaa4d3f51a17fd6d06eabab042 516 Gene3D G3DSA:3.90.1100.10 347 509 6.3E-52 T 23-10-2018 Mlab_1163 7e58afaaa4d3f51a17fd6d06eabab042 516 Gene3D G3DSA:3.90.1100.10 11 170 4.4E-8 T 23-10-2018 Mlab_1163 7e58afaaa4d3f51a17fd6d06eabab042 516 SUPERFAMILY SSF64484 6 513 1.07E-119 T 23-10-2018 Mlab_1163 7e58afaaa4d3f51a17fd6d06eabab042 516 Pfam PF04563 RNA polymerase beta subunit 18 407 2.0E-49 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_0717 8220c3afc0338c5470ecaf4d40e99c5c 312 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0717 8220c3afc0338c5470ecaf4d40e99c5c 312 SMART SM00382 33 229 5.0E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0717 8220c3afc0338c5470ecaf4d40e99c5c 312 Pfam PF00005 ABC transporter 25 181 5.3E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0717 8220c3afc0338c5470ecaf4d40e99c5c 312 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 310 2.1E-23 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Mlab_0717 8220c3afc0338c5470ecaf4d40e99c5c 312 Gene3D G3DSA:3.40.50.300 1 312 1.0E-79 T 23-10-2018 Mlab_0717 8220c3afc0338c5470ecaf4d40e99c5c 312 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 291 1.2E-15 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Mlab_0717 8220c3afc0338c5470ecaf4d40e99c5c 312 SUPERFAMILY SSF52540 4 251 5.81E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0392 929fcc267229efc06991811deecb6063 309 SUPERFAMILY SSF49464 124 197 1.16E-5 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily Mlab_1430 a7bb963e7537066712d15b64f4f02f8f 245 Pfam PF08759 Glycosyltransferase GT-D fold 1 217 3.9E-81 T 23-10-2018 IPR014869 Glycosyltransferase GT-D fold Mlab_1430 a7bb963e7537066712d15b64f4f02f8f 245 TIGRFAM TIGR03728 glyco_access_1: glycosyltransferase, SP_1767 family 1 241 2.5E-97 T 23-10-2018 IPR014869 Glycosyltransferase GT-D fold Mlab_0864 70b14c1d7d3f8d2345e17eeecdb28740 524 Pfam PF00474 Sodium:solute symporter family 39 452 6.7E-57 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Mlab_0864 70b14c1d7d3f8d2345e17eeecdb28740 524 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 434 454 - T 23-10-2018 IPR018212 Sodium/solute symporter, conserved site Mlab_0864 70b14c1d7d3f8d2345e17eeecdb28740 524 Gene3D G3DSA:1.20.1730.10 10 516 1.6E-77 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily Mlab_1420 f01c5556c50d101275528daffee542df 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 66 369 6.6E-76 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Mlab_1420 f01c5556c50d101275528daffee542df 399 SUPERFAMILY SSF53686 2 393 4.71E-114 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Mlab_1420 f01c5556c50d101275528daffee542df 399 Gene3D G3DSA:3.40.50.1100 103 199 1.8E-126 T 23-10-2018 Mlab_1420 f01c5556c50d101275528daffee542df 399 TIGRFAM TIGR00260 thrC: threonine synthase 53 376 1.5E-104 T 23-10-2018 IPR004450 Threonine synthase-like Mlab_1420 f01c5556c50d101275528daffee542df 399 Gene3D G3DSA:3.40.50.1100 54 375 1.8E-126 T 23-10-2018 Mlab_1420 f01c5556c50d101275528daffee542df 399 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 94 108 - T 23-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Mlab_1420 f01c5556c50d101275528daffee542df 399 PIRSF PIRSF038945 35 399 2.5E-148 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 Mlab_0167 9e2e5e3a440d1b7be177009f187cd19e 295 Pfam PF00005 ABC transporter 28 182 6.7E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0167 9e2e5e3a440d1b7be177009f187cd19e 295 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0167 9e2e5e3a440d1b7be177009f187cd19e 295 SUPERFAMILY SSF52540 6 253 2.66E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0167 9e2e5e3a440d1b7be177009f187cd19e 295 SMART SM00382 36 231 1.3E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0167 9e2e5e3a440d1b7be177009f187cd19e 295 Gene3D G3DSA:3.40.50.300 4 290 1.8E-77 T 23-10-2018 Mlab_1572 2635d3d11dff0d36a3aa08ffbb89f606 193 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 8 172 2.0E-48 T 23-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 Mlab_1572 2635d3d11dff0d36a3aa08ffbb89f606 193 Pfam PF05175 Methyltransferase small domain 15 96 3.0E-5 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 Mlab_1572 2635d3d11dff0d36a3aa08ffbb89f606 193 Gene3D G3DSA:3.40.50.150 6 189 1.2E-40 T 23-10-2018 Mlab_1572 2635d3d11dff0d36a3aa08ffbb89f606 193 SUPERFAMILY SSF53335 6 168 1.67E-27 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0394 1987e87d87bdb687dff0bbf2d6241c04 303 Gene3D G3DSA:3.30.420.40 4 293 4.1E-71 T 23-10-2018 Mlab_0394 1987e87d87bdb687dff0bbf2d6241c04 303 Gene3D G3DSA:3.30.420.150 105 285 4.1E-71 T 23-10-2018 Mlab_0394 1987e87d87bdb687dff0bbf2d6241c04 303 Pfam PF02541 Ppx/GppA phosphatase family 39 298 7.6E-46 T 23-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 Mlab_0394 1987e87d87bdb687dff0bbf2d6241c04 303 SUPERFAMILY SSF53067 2 121 2.94E-28 T 23-10-2018 Mlab_0394 1987e87d87bdb687dff0bbf2d6241c04 303 SUPERFAMILY SSF53067 125 297 7.08E-33 T 23-10-2018 Mlab_1185 c6a53babfb3d30fc4b4859940a1a9520 445 Pfam PF13173 AAA domain 18 152 5.8E-31 T 23-10-2018 Mlab_1185 c6a53babfb3d30fc4b4859940a1a9520 445 Pfam PF13635 Domain of unknown function (DUF4143) 224 386 1.3E-19 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 Mlab_1185 c6a53babfb3d30fc4b4859940a1a9520 445 SUPERFAMILY SSF52540 4 219 4.07E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1185 c6a53babfb3d30fc4b4859940a1a9520 445 Gene3D G3DSA:3.40.50.300 3 81 7.7E-6 T 23-10-2018 Mlab_0040 ac417429b1d96a75864735951c6ef8ef 274 SUPERFAMILY SSF53335 53 205 3.25E-20 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0040 ac417429b1d96a75864735951c6ef8ef 274 Gene3D G3DSA:3.40.50.150 2 199 1.7E-16 T 23-10-2018 Mlab_0040 ac417429b1d96a75864735951c6ef8ef 274 Pfam PF13489 Methyltransferase domain 58 162 1.2E-10 T 23-10-2018 Mlab_1153 bd3f78d9a31c1cacdc616355d519cc6d 375 SUPERFAMILY SSF81345 14 368 6.02E-83 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_1153 bd3f78d9a31c1cacdc616355d519cc6d 375 Pfam PF01032 FecCD transport family 32 368 5.5E-89 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Mlab_1153 bd3f78d9a31c1cacdc616355d519cc6d 375 Gene3D G3DSA:1.10.3470.10 19 373 2.8E-103 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 Gene3D G3DSA:1.20.970.10 85 152 4.5E-20 T 23-10-2018 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 Pfam PF02885 Glycosyl transferase family, helical bundle domain 91 151 3.4E-10 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 Hamap MF_02132 AMP phosphorylase. 1 504 47.269 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 PIRSF PIRSF000478 85 504 4.5E-120 T 23-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 Gene3D G3DSA:3.40.1030.10 153 413 1.3E-86 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 SMART SM00941 425 492 3.2E-25 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 SUPERFAMILY SSF52418 156 405 1.18E-63 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 SUPERFAMILY SSF47648 89 154 1.44E-13 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 Gene3D G3DSA:3.90.1170.30 414 494 8.5E-22 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 SUPERFAMILY SSF54680 412 496 3.01E-16 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 8 495 1.6E-168 T 23-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 194 209 - T 23-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 Pfam PF00591 Glycosyl transferase family, a/b domain 159 387 3.3E-9 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 425 490 1.2E-13 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Mlab_0067 261ec21ee7179b21c727a92072ccf075 505 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 7 501 7.8E-203 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 Mlab_0343 6126d5755a6fe15b28f1428ee5b66504 368 Gene3D G3DSA:3.20.20.70 32 320 2.7E-89 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0343 6126d5755a6fe15b28f1428ee5b66504 368 SUPERFAMILY SSF102114 86 310 2.75E-19 T 23-10-2018 Mlab_0343 6126d5755a6fe15b28f1428ee5b66504 368 TIGRFAM TIGR00238 TIGR00238: KamA family protein 8 304 2.2E-61 T 23-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase Mlab_0343 6126d5755a6fe15b28f1428ee5b66504 368 PIRSF PIRSF004911 2 362 7.5E-96 T 23-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase Mlab_0343 6126d5755a6fe15b28f1428ee5b66504 368 Pfam PF13394 4Fe-4S single cluster domain 100 174 7.3E-5 T 23-10-2018 Mlab_1410 425507130c14918dd433b7b682e398ee 270 Pfam PF01734 Patatin-like phospholipase 1 158 2.3E-13 T 23-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Mlab_1410 425507130c14918dd433b7b682e398ee 270 Gene3D G3DSA:3.40.1090.10 74 217 2.6E-9 T 23-10-2018 Mlab_1410 425507130c14918dd433b7b682e398ee 270 SUPERFAMILY SSF52151 1 260 2.88E-33 T 23-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 Pfam PF00005 ABC transporter 615 851 1.4E-9 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 931 22.096 T 23-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 Gene3D G3DSA:1.20.1580.10 90 486 3.6E-239 T 23-10-2018 Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 Gene3D G3DSA:3.30.190.20 130 239 3.6E-239 T 23-10-2018 Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 Gene3D G3DSA:3.40.50.300 5 588 3.6E-239 T 23-10-2018 Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 Gene3D G3DSA:3.40.50.300 605 927 2.4E-142 T 23-10-2018 Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 SUPERFAMILY SSF52540 1 563 3.61E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 SUPERFAMILY SSF52540 612 904 3.33E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 916 0.0 T 23-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 Gene3D G3DSA:1.20.1580.10 684 821 2.4E-142 T 23-10-2018 Mlab_0976 c28c342dfb0475e0e267c2202972db33 931 Gene3D G3DSA:1.10.8.280 282 397 3.6E-239 T 23-10-2018 Mlab_0367 fbb23f35a22538c753858546355cacb8 404 SUPERFAMILY SSF52402 173 376 8.16E-41 T 23-10-2018 Mlab_0367 fbb23f35a22538c753858546355cacb8 404 Pfam PF02926 THUMP domain 31 154 6.8E-14 T 23-10-2018 IPR004114 THUMP domain GO:0003723 Mlab_0367 fbb23f35a22538c753858546355cacb8 404 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 404 110.168 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 Mlab_0367 fbb23f35a22538c753858546355cacb8 404 SUPERFAMILY SSF143437 7 172 2.62E-35 T 23-10-2018 Mlab_0367 fbb23f35a22538c753858546355cacb8 404 Gene3D G3DSA:3.40.50.620 174 385 1.2E-61 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0367 fbb23f35a22538c753858546355cacb8 404 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 174 368 4.7E-54 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 Mlab_0367 fbb23f35a22538c753858546355cacb8 404 SMART SM00981 74 164 1.9E-15 T 23-10-2018 IPR004114 THUMP domain GO:0003723 Mlab_0367 fbb23f35a22538c753858546355cacb8 404 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 7 371 8.2E-82 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 Mlab_0367 fbb23f35a22538c753858546355cacb8 404 Gene3D G3DSA:3.30.2130.30 1 173 3.4E-35 T 23-10-2018 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 120 4.9E-28 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 355 410 5.6E-12 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 Gene3D G3DSA:3.40.120.10 238 311 9.2E-47 T 23-10-2018 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 SUPERFAMILY SSF53738 2 163 4.41E-30 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 SUPERFAMILY SSF53738 152 239 2.79E-20 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 SUPERFAMILY SSF55957 346 415 1.57E-15 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 Gene3D G3DSA:3.40.120.10 1 134 4.6E-33 T 23-10-2018 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 154 237 5.7E-20 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 Gene3D G3DSA:3.30.310.50 342 415 2.1E-16 T 23-10-2018 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 83 92 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 Gene3D G3DSA:3.40.120.10 156 325 9.2E-47 T 23-10-2018 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 241 326 5.9E-16 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 SUPERFAMILY SSF53738 241 327 1.88E-15 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 82 96 3.0E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 217 232 3.0E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0667 d5d1d17e3b1daac3975b9b2de1682ed6 419 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 156 175 3.0E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Mlab_0275 4329ecc5457b70625ee0a0378df01772 263 Pfam PF01975 Survival protein SurE 6 196 6.9E-53 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Mlab_0275 4329ecc5457b70625ee0a0378df01772 263 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 4 263 33.523 T 23-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Mlab_0275 4329ecc5457b70625ee0a0378df01772 263 Gene3D G3DSA:3.40.1210.10 5 262 3.6E-81 T 23-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Mlab_0275 4329ecc5457b70625ee0a0378df01772 263 SUPERFAMILY SSF64167 5 260 5.75E-73 T 23-10-2018 Mlab_0275 4329ecc5457b70625ee0a0378df01772 263 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 5 246 1.1E-67 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Mlab_0558 63bb4dcaa4296507015e1365bf26b011 403 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 2 109 1.1E-24 T 23-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Mlab_0558 63bb4dcaa4296507015e1365bf26b011 403 Gene3D G3DSA:3.20.20.110 114 403 8.6E-115 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Mlab_0558 63bb4dcaa4296507015e1365bf26b011 403 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 120 400 1.4E-85 T 23-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Mlab_0558 63bb4dcaa4296507015e1365bf26b011 403 Gene3D G3DSA:3.30.70.150 1 111 8.1E-30 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Mlab_0558 63bb4dcaa4296507015e1365bf26b011 403 SUPERFAMILY SSF54966 1 110 1.7E-28 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Mlab_0558 63bb4dcaa4296507015e1365bf26b011 403 SUPERFAMILY SSF51649 115 401 1.2E-99 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Mlab_0718 41629cfdc42b3b046fbb0890ee46e18f 282 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 43 2.9E-8 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Mlab_0718 41629cfdc42b3b046fbb0890ee46e18f 282 Gene3D G3DSA:1.10.3720.10 63 271 3.8E-21 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0718 41629cfdc42b3b046fbb0890ee46e18f 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 275 1.9E-29 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_0718 41629cfdc42b3b046fbb0890ee46e18f 282 SUPERFAMILY SSF161098 70 259 4.06E-26 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1551 250ec66e4f0c844ec95242827f460aa8 153 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 14 144 7.8E-18 T 23-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain Mlab_1551 250ec66e4f0c844ec95242827f460aa8 153 SUPERFAMILY SSF143555 4 149 1.31E-25 T 23-10-2018 Mlab_1551 250ec66e4f0c844ec95242827f460aa8 153 Gene3D G3DSA:3.30.1330.130 1 145 4.6E-13 T 23-10-2018 Mlab_1580 dda83ba90e598922310a0b8b80abf63e 282 Gene3D G3DSA:3.90.105.20 106 185 9.4E-64 T 23-10-2018 Mlab_1580 dda83ba90e598922310a0b8b80abf63e 282 Gene3D G3DSA:3.30.70.1730 19 209 9.4E-64 T 23-10-2018 Mlab_1580 dda83ba90e598922310a0b8b80abf63e 282 Pfam PF00466 Ribosomal protein L10 9 104 1.1E-19 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 Mlab_1580 dda83ba90e598922310a0b8b80abf63e 282 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 5 282 32.664 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea Mlab_1580 dda83ba90e598922310a0b8b80abf63e 282 SUPERFAMILY SSF160369 8 139 4.05E-22 T 23-10-2018 Mlab_0353 ba6241bf68b3b41f920b0339da37b0f3 168 SMART SM00347 29 145 2.5E-10 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0353 ba6241bf68b3b41f920b0339da37b0f3 168 SUPERFAMILY SSF46785 7 159 3.19E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0353 ba6241bf68b3b41f920b0339da37b0f3 168 Gene3D G3DSA:1.10.10.10 2 158 6.0E-29 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0353 ba6241bf68b3b41f920b0339da37b0f3 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 85 1.4E-10 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0353 ba6241bf68b3b41f920b0339da37b0f3 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 1.4E-10 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0353 ba6241bf68b3b41f920b0339da37b0f3 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 1.4E-10 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0353 ba6241bf68b3b41f920b0339da37b0f3 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 1.4E-10 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0353 ba6241bf68b3b41f920b0339da37b0f3 168 Pfam PF12802 MarR family 35 109 9.3E-9 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0728 6ef84186b2e6e98e5efc66d4665bced6 112 Pfam PF07883 Cupin domain 48 90 1.2E-9 T 23-10-2018 IPR013096 Cupin 2, conserved barrel Mlab_0728 6ef84186b2e6e98e5efc66d4665bced6 112 SUPERFAMILY SSF51182 32 103 1.16E-13 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily Mlab_0728 6ef84186b2e6e98e5efc66d4665bced6 112 Gene3D G3DSA:2.60.120.10 13 110 8.7E-14 T 23-10-2018 IPR014710 RmlC-like jelly roll fold Mlab_0897 3980b33d2db021565fc2f3743c8b8767 337 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 254 1.9E-59 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Mlab_0897 3980b33d2db021565fc2f3743c8b8767 337 SUPERFAMILY SSF51735 5 323 1.24E-92 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0897 3980b33d2db021565fc2f3743c8b8767 337 PRINTS PR01713 Nucleotide sugar epimerase signature 248 263 5.0E-25 T 23-10-2018 Mlab_0897 3980b33d2db021565fc2f3743c8b8767 337 PRINTS PR01713 Nucleotide sugar epimerase signature 32 48 5.0E-25 T 23-10-2018 Mlab_0897 3980b33d2db021565fc2f3743c8b8767 337 PRINTS PR01713 Nucleotide sugar epimerase signature 219 234 5.0E-25 T 23-10-2018 Mlab_0897 3980b33d2db021565fc2f3743c8b8767 337 PRINTS PR01713 Nucleotide sugar epimerase signature 287 304 5.0E-25 T 23-10-2018 Mlab_0897 3980b33d2db021565fc2f3743c8b8767 337 Gene3D G3DSA:3.40.50.720 7 308 2.1E-100 T 23-10-2018 Mlab_0897 3980b33d2db021565fc2f3743c8b8767 337 Gene3D G3DSA:3.90.25.10 183 320 2.1E-100 T 23-10-2018 Mlab_1497 ee6867f71535b571c10efcc24520221a 122 SUPERFAMILY SSF55315 4 120 6.77E-32 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like Mlab_1497 ee6867f71535b571c10efcc24520221a 122 PRINTS PR00884 Ribosomal protein HS6 signature 39 49 3.3E-20 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1497 ee6867f71535b571c10efcc24520221a 122 PRINTS PR00884 Ribosomal protein HS6 signature 5 16 3.3E-20 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1497 ee6867f71535b571c10efcc24520221a 122 PRINTS PR00884 Ribosomal protein HS6 signature 49 60 3.3E-20 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1497 ee6867f71535b571c10efcc24520221a 122 PRINTS PR00884 Ribosomal protein HS6 signature 76 86 3.3E-20 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1497 ee6867f71535b571c10efcc24520221a 122 PRINTS PR00884 Ribosomal protein HS6 signature 90 106 3.3E-20 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1497 ee6867f71535b571c10efcc24520221a 122 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 2 121 29.506 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1497 ee6867f71535b571c10efcc24520221a 122 Gene3D G3DSA:3.30.1330.30 1 122 1.2E-31 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like Mlab_1497 ee6867f71535b571c10efcc24520221a 122 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 5 121 2.1E-51 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1497 ee6867f71535b571c10efcc24520221a 122 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 17 109 1.1E-23 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 Mlab_1497 ee6867f71535b571c10efcc24520221a 122 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 76 90 2.2E-15 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family Mlab_1497 ee6867f71535b571c10efcc24520221a 122 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 66 76 2.2E-15 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family Mlab_1497 ee6867f71535b571c10efcc24520221a 122 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 31 45 2.2E-15 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family Mlab_1497 ee6867f71535b571c10efcc24520221a 122 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 50 63 2.2E-15 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family Mlab_0593 a2e6e535e5ecf803df9bd69a61b71330 294 Pfam PF01180 Dihydroorotate dehydrogenase 9 278 1.8E-53 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 Mlab_0593 a2e6e535e5ecf803df9bd69a61b71330 294 Gene3D G3DSA:3.20.20.70 16 277 1.9E-75 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0593 a2e6e535e5ecf803df9bd69a61b71330 294 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 9 293 1.1E-90 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 Mlab_0593 a2e6e535e5ecf803df9bd69a61b71330 294 PIRSF PIRSF000164 4 294 2.5E-64 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Mlab_0593 a2e6e535e5ecf803df9bd69a61b71330 294 SUPERFAMILY SSF51395 10 277 1.19E-63 T 23-10-2018 Mlab_0593 a2e6e535e5ecf803df9bd69a61b71330 294 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 234 254 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 Mlab_0593 a2e6e535e5ecf803df9bd69a61b71330 294 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 2 292 31.192 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 Mlab_0593 a2e6e535e5ecf803df9bd69a61b71330 294 Gene3D G3DSA:2.30.26.10 58 211 1.9E-75 T 23-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 Mlab_1440 92987e18dfd538c79109648afb55263f 102 SMART SM01403 5 99 7.6E-39 T 23-10-2018 IPR027486 Ribosomal protein S10 domain Mlab_1440 92987e18dfd538c79109648afb55263f 102 Gene3D G3DSA:3.30.70.600 1 100 1.3E-33 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily Mlab_1440 92987e18dfd538c79109648afb55263f 102 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 5.8E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1440 92987e18dfd538c79109648afb55263f 102 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 5.8E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1440 92987e18dfd538c79109648afb55263f 102 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 5.8E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1440 92987e18dfd538c79109648afb55263f 102 SUPERFAMILY SSF54999 3 99 3.01E-28 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily Mlab_1440 92987e18dfd538c79109648afb55263f 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 23-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1440 92987e18dfd538c79109648afb55263f 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 2 99 4.7E-48 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1440 92987e18dfd538c79109648afb55263f 102 Pfam PF00338 Ribosomal protein S10p/S20e 5 98 4.4E-27 T 23-10-2018 IPR027486 Ribosomal protein S10 domain Mlab_1440 92987e18dfd538c79109648afb55263f 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 24.494 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0452 ed7a5705c10c8db8ad59e0fa77c3fb0c 128 Pfam PF12800 4Fe-4S binding domain 79 90 0.07 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0452 ed7a5705c10c8db8ad59e0fa77c3fb0c 128 Gene3D G3DSA:3.30.70.20 65 125 1.2E-11 T 23-10-2018 Mlab_0452 ed7a5705c10c8db8ad59e0fa77c3fb0c 128 Pfam PF00037 4Fe-4S binding domain 103 124 3.5E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0452 ed7a5705c10c8db8ad59e0fa77c3fb0c 128 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 109 120 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0452 ed7a5705c10c8db8ad59e0fa77c3fb0c 128 SUPERFAMILY SSF54862 52 126 1.13E-17 T 23-10-2018 Mlab_1004 6dee10e93f9f003e699a68f6213bad2b 216 Gene3D G3DSA:1.10.340.30 24 135 6.7E-72 T 23-10-2018 Mlab_1004 6dee10e93f9f003e699a68f6213bad2b 216 SUPERFAMILY SSF48150 4 211 1.73E-65 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Mlab_1004 6dee10e93f9f003e699a68f6213bad2b 216 TIGRFAM TIGR01083 nth: endonuclease III 6 198 1.9E-69 T 23-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 Mlab_1004 6dee10e93f9f003e699a68f6213bad2b 216 Gene3D G3DSA:1.10.1670.10 22 207 6.7E-72 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 Mlab_1004 6dee10e93f9f003e699a68f6213bad2b 216 SMART SM00478 41 189 5.5E-55 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Mlab_1004 6dee10e93f9f003e699a68f6213bad2b 216 Pfam PF00633 Helix-hairpin-helix motif 103 128 2.3E-9 T 23-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 Mlab_1004 6dee10e93f9f003e699a68f6213bad2b 216 PIRSF PIRSF001435 4 215 8.8E-48 T 23-10-2018 Mlab_1004 6dee10e93f9f003e699a68f6213bad2b 216 Hamap MF_00942 Endonuclease III [nth]. 4 213 35.143 T 23-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 Mlab_1004 6dee10e93f9f003e699a68f6213bad2b 216 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 37 172 4.2E-23 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Mlab_1603 98ca849ebf62623525ac904f17b2ae79 347 Pfam PF01381 Helix-turn-helix 6 60 3.4E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_1603 98ca849ebf62623525ac904f17b2ae79 347 SMART SM00530 5 60 3.9E-16 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_1603 98ca849ebf62623525ac904f17b2ae79 347 Gene3D G3DSA:1.10.260.40 1 104 8.9E-21 T 23-10-2018 Mlab_1603 98ca849ebf62623525ac904f17b2ae79 347 SUPERFAMILY SSF47413 1 64 4.83E-18 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Mlab_1603 98ca849ebf62623525ac904f17b2ae79 347 Pfam PF06114 IrrE N-terminal-like domain 184 270 9.6E-10 T 23-10-2018 IPR010359 IrrE N-terminal-like domain Mlab_0290 756e758cf616b49a89a3fa63e462b4b8 152 Pfam PF00312 Ribosomal protein S15 80 148 4.2E-13 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0290 756e758cf616b49a89a3fa63e462b4b8 152 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 32.311 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0290 756e758cf616b49a89a3fa63e462b4b8 152 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0290 756e758cf616b49a89a3fa63e462b4b8 152 SMART SM01386 1 60 7.2E-33 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0290 756e758cf616b49a89a3fa63e462b4b8 152 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 1.1E-25 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0290 756e758cf616b49a89a3fa63e462b4b8 152 SUPERFAMILY SSF47060 67 142 1.03E-17 T 23-10-2018 IPR009068 S15/NS1, RNA-binding Mlab_0290 756e758cf616b49a89a3fa63e462b4b8 152 Gene3D G3DSA:1.10.287.10 83 151 4.3E-28 T 23-10-2018 Mlab_0290 756e758cf616b49a89a3fa63e462b4b8 152 Gene3D G3DSA:1.10.8.1030 35 82 1.4E-16 T 23-10-2018 Mlab_0290 756e758cf616b49a89a3fa63e462b4b8 152 SMART SM01387 71 149 2.4E-12 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0606 bc9a0cc42ff707de46cb1cf2134018aa 167 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 159 1.6E-63 T 23-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Mlab_0606 bc9a0cc42ff707de46cb1cf2134018aa 167 Pfam PF10369 Small subunit of acetolactate synthase 85 159 6.2E-30 T 23-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Mlab_0606 bc9a0cc42ff707de46cb1cf2134018aa 167 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 4.0E-26 T 23-10-2018 Mlab_0606 bc9a0cc42ff707de46cb1cf2134018aa 167 SUPERFAMILY SSF55021 77 159 1.5E-26 T 23-10-2018 Mlab_0606 bc9a0cc42ff707de46cb1cf2134018aa 167 Pfam PF13710 ACT domain 13 74 1.3E-18 T 23-10-2018 Mlab_0606 bc9a0cc42ff707de46cb1cf2134018aa 167 Gene3D G3DSA:3.30.70.1150 84 164 7.9E-30 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal Mlab_0606 bc9a0cc42ff707de46cb1cf2134018aa 167 Gene3D G3DSA:3.30.70.260 1 80 6.6E-37 T 23-10-2018 Mlab_0606 bc9a0cc42ff707de46cb1cf2134018aa 167 SUPERFAMILY SSF55021 3 77 6.72E-23 T 23-10-2018 Mlab_0019 e0c181306f447115fed60cc86d6771cb 346 SUPERFAMILY SSF51735 24 203 1.03E-60 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0019 e0c181306f447115fed60cc86d6771cb 346 PIRSF PIRSF000116 9 344 1.3E-44 T 23-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Mlab_0019 e0c181306f447115fed60cc86d6771cb 346 SUPERFAMILY SSF48179 204 345 1.5E-51 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Mlab_0019 e0c181306f447115fed60cc86d6771cb 346 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 37 344 2.0E-114 T 23-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Mlab_0019 e0c181306f447115fed60cc86d6771cb 346 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 36 197 8.0E-63 T 23-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Mlab_0019 e0c181306f447115fed60cc86d6771cb 346 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 23 346 36.324 T 23-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Mlab_0019 e0c181306f447115fed60cc86d6771cb 346 Gene3D G3DSA:1.10.3730.40 203 346 4.8E-56 T 23-10-2018 Mlab_0019 e0c181306f447115fed60cc86d6771cb 346 Gene3D G3DSA:3.40.50.720 22 202 1.0E-66 T 23-10-2018 Mlab_0019 e0c181306f447115fed60cc86d6771cb 346 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 204 344 1.4E-50 T 23-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Mlab_1032 df3348e5c3a58b4d502c190d7c0dc87e 348 SMART SM00729 33 240 0.003 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_1032 df3348e5c3a58b4d502c190d7c0dc87e 348 SUPERFAMILY SSF47781 277 333 7.11E-6 T 23-10-2018 IPR010994 RuvA domain 2-like Mlab_1032 df3348e5c3a58b4d502c190d7c0dc87e 348 SUPERFAMILY SSF102114 35 241 1.19E-16 T 23-10-2018 Mlab_1032 df3348e5c3a58b4d502c190d7c0dc87e 348 Gene3D G3DSA:3.20.20.70 23 253 2.1E-10 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1032 df3348e5c3a58b4d502c190d7c0dc87e 348 Pfam PF04055 Radical SAM superfamily 43 195 2.7E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_1258 6321d6212551e9a83bf6f891ee6a696a 578 SUPERFAMILY SSF90123 7 317 1.96E-71 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Mlab_1258 6321d6212551e9a83bf6f891ee6a696a 578 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1258 6321d6212551e9a83bf6f891ee6a696a 578 Gene3D G3DSA:1.20.1560.10 1 318 1.9E-82 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Mlab_1258 6321d6212551e9a83bf6f891ee6a696a 578 Gene3D G3DSA:3.40.50.300 331 578 5.5E-79 T 23-10-2018 Mlab_1258 6321d6212551e9a83bf6f891ee6a696a 578 SUPERFAMILY SSF52540 325 572 7.88E-84 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1258 6321d6212551e9a83bf6f891ee6a696a 578 Pfam PF00664 ABC transporter transmembrane region 24 290 3.2E-42 T 23-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Mlab_1258 6321d6212551e9a83bf6f891ee6a696a 578 SMART SM00382 362 548 3.5E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1258 6321d6212551e9a83bf6f891ee6a696a 578 Pfam PF00005 ABC transporter 353 502 4.8E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0342 40891b99df7c46c71fe79a425b9c627b 124 Pfam PF02001 Protein of unknown function DUF134 7 81 9.4E-16 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 Mlab_0342 40891b99df7c46c71fe79a425b9c627b 124 Gene3D G3DSA:1.10.10.10 24 73 3.3E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0342 40891b99df7c46c71fe79a425b9c627b 124 SUPERFAMILY SSF88659 25 72 8.97E-5 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Mlab_0224 8a8588be89c55016b5fdb7f95df20564 168 Hamap MF_01116 Probable ribosome biogenesis protein . 5 168 32.103 T 23-10-2018 IPR022968 Ribosome biogenesis protein Reactome: R-HSA-6790901 Mlab_0224 8a8588be89c55016b5fdb7f95df20564 168 ProDom PD016638 UPF0293 SIMILAR RNASE YOR006C RNA COMPONENT SACCHAROMYCES P RIKEN CERVISIAE 25 167 3.0E-47 T 23-10-2018 IPR007177 Ribosome biogenesis protein, C-terminal Reactome: R-HSA-6790901 Mlab_0224 8a8588be89c55016b5fdb7f95df20564 168 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 8 33 2.2E-7 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain Mlab_0224 8a8588be89c55016b5fdb7f95df20564 168 Pfam PF04034 Ribosome biogenesis protein, C-terminal 45 167 4.4E-44 T 23-10-2018 IPR007177 Ribosome biogenesis protein, C-terminal Reactome: R-HSA-6790901 Mlab_1000 696aa28aaebde07c99f785a6f22f4706 177 Pfam PF03703 Bacterial PH domain 50 129 1.1E-18 T 23-10-2018 IPR005182 Domain of unknown function DUF304 Mlab_0933 82f1054243af9012c58b5d78365a4d3c 218 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 216 7.5E-82 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding Mlab_0933 82f1054243af9012c58b5d78365a4d3c 218 PIRSF PIRSF039123 1 218 1.0E-76 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 Mlab_0933 82f1054243af9012c58b5d78365a4d3c 218 Pfam PF01902 Diphthamide synthase 1 216 5.0E-63 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 Mlab_0933 82f1054243af9012c58b5d78365a4d3c 218 SUPERFAMILY SSF52402 1 212 1.84E-58 T 23-10-2018 Mlab_0933 82f1054243af9012c58b5d78365a4d3c 218 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 216 2.6E-62 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 Mlab_0933 82f1054243af9012c58b5d78365a4d3c 218 Gene3D G3DSA:3.40.50.620 1 122 1.7E-38 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0933 82f1054243af9012c58b5d78365a4d3c 218 Gene3D G3DSA:3.90.1490.10 123 218 7.9E-21 T 23-10-2018 Mlab_0960 aa391f15ed4a8e9f2ff77cc5e3634740 333 Pfam PF00146 NADH dehydrogenase 12 323 4.7E-63 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0852 d8c14d0eff91022979ec4924f843d7a4 344 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 8 335 2.1E-79 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Mlab_0852 d8c14d0eff91022979ec4924f843d7a4 344 Pfam PF01867 CRISPR associated protein Cas1 8 299 1.1E-100 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Mlab_0852 d8c14d0eff91022979ec4924f843d7a4 344 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 329 26.333 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Mlab_0852 d8c14d0eff91022979ec4924f843d7a4 344 Gene3D G3DSA:3.100.10.20 6 82 1.1E-15 T 23-10-2018 Mlab_0852 d8c14d0eff91022979ec4924f843d7a4 344 TIGRFAM TIGR03640 cas1_DVULG: CRISPR-associated endonuclease Cas1, subtype I-C/DVULG 3 342 6.5E-141 T 23-10-2018 IPR019856 CRISPR-associated protein Cas1, DVULG subtype GO:0004520|GO:0043571|GO:0046872 Mlab_0852 d8c14d0eff91022979ec4924f843d7a4 344 Gene3D G3DSA:1.20.120.920 86 344 1.4E-76 T 23-10-2018 Mlab_0045 6e2ec187d05a0db940322ec91b377ae7 207 SMART SM00382 28 207 1.9E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0045 6e2ec187d05a0db940322ec91b377ae7 207 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0045 6e2ec187d05a0db940322ec91b377ae7 207 Pfam PF00005 ABC transporter 19 162 5.4E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0045 6e2ec187d05a0db940322ec91b377ae7 207 SUPERFAMILY SSF52540 3 207 7.71E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0045 6e2ec187d05a0db940322ec91b377ae7 207 Gene3D G3DSA:3.40.50.300 1 207 1.2E-61 T 23-10-2018 Mlab_0234 6da54feb8765ba1942badeff91d86c0b 158 Gene3D G3DSA:3.20.19.10 1 154 9.1E-45 T 23-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Mlab_0234 6da54feb8765ba1942badeff91d86c0b 158 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 152 1.2E-44 T 23-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 Mlab_0234 6da54feb8765ba1942badeff91d86c0b 158 Pfam PF00694 Aconitase C-terminal domain 52 99 2.5E-17 T 23-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Mlab_0234 6da54feb8765ba1942badeff91d86c0b 158 SUPERFAMILY SSF52016 2 152 3.53E-39 T 23-10-2018 Mlab_0958 4fa4f0ebf259fd0019967ebd1c7221ee 193 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 45 165 1.1E-17 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0958 4fa4f0ebf259fd0019967ebd1c7221ee 193 Gene3D G3DSA:3.30.460.80 20 146 8.3E-16 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0958 4fa4f0ebf259fd0019967ebd1c7221ee 193 SUPERFAMILY SSF143243 9 173 4.32E-26 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0958 4fa4f0ebf259fd0019967ebd1c7221ee 193 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 110 154 9.0E-8 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0831 1c55f197f04699bdd5ad530b636035f0 107 Pfam PF04038 Dihydroneopterin aldolase 3 105 3.4E-39 T 23-10-2018 IPR007181 Dihydroneopterin aldolase MtpD, C-terminal domain KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Mlab_0831 1c55f197f04699bdd5ad530b636035f0 107 ProDom PD027636 ARCHAEA UNCHARACTERIZED TVG0753807 MA0117 VNG0127C MJ0408 3 49 2.0E-8 T 23-10-2018 IPR007179 7,8-dihydroneopterin aldolase MtpD, N-terminal domain KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Mlab_0831 1c55f197f04699bdd5ad530b636035f0 107 Hamap MF_02130 Dihydroneopterin aldolase [mptD]. 1 107 28.444 T 23-10-2018 IPR027508 7,8-dihydroneopterin aldolase, MptD GO:0004150 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Mlab_0831 1c55f197f04699bdd5ad530b636035f0 107 Gene3D G3DSA:3.30.1300.20 1 107 2.5E-37 T 23-10-2018 IPR036839 7,8-dihydroneopterin aldolase (MptD) superfamily GO:0004150 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Mlab_0831 1c55f197f04699bdd5ad530b636035f0 107 SUPERFAMILY SSF143560 2 106 1.7E-40 T 23-10-2018 IPR036839 7,8-dihydroneopterin aldolase (MptD) superfamily GO:0004150 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Mlab_1189 43499b6dbd4fa184d79ce515ae2b0653 344 SMART SM00849 89 318 9.3E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1189 43499b6dbd4fa184d79ce515ae2b0653 344 SUPERFAMILY SSF56281 72 322 7.34E-26 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1189 43499b6dbd4fa184d79ce515ae2b0653 344 Pfam PF00753 Metallo-beta-lactamase superfamily 94 266 3.4E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1189 43499b6dbd4fa184d79ce515ae2b0653 344 Gene3D G3DSA:3.60.15.10 64 329 2.0E-22 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1317 8f81c4928571e558cd2e98f1b0cdc0ab 238 SUPERFAMILY SSF53335 9 197 1.82E-25 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1317 8f81c4928571e558cd2e98f1b0cdc0ab 238 Gene3D G3DSA:3.40.50.150 16 237 2.0E-23 T 23-10-2018 Mlab_1317 8f81c4928571e558cd2e98f1b0cdc0ab 238 Pfam PF08241 Methyltransferase domain 44 142 9.0E-10 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Mlab_1327 ac69233dac89797b209c28d91de6a069 223 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 136 219 1.0E-7 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Mlab_1327 ac69233dac89797b209c28d91de6a069 223 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 1 112 1.0E-7 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Mlab_1327 ac69233dac89797b209c28d91de6a069 223 Pfam PF01950 Fructose-1,6-bisphosphatase 141 219 4.3E-9 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Mlab_1327 ac69233dac89797b209c28d91de6a069 223 Pfam PF01950 Fructose-1,6-bisphosphatase 3 86 8.1E-8 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Mlab_1327 ac69233dac89797b209c28d91de6a069 223 SUPERFAMILY SSF111249 3 219 3.66E-22 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 SUPERFAMILY SSF52374 4 378 2.33E-100 T 23-10-2018 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 Pfam PF09334 tRNA synthetases class I (M) 7 391 1.6E-148 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 Hamap MF_00098 Methionine--tRNA ligase [metG]. 4 541 38.093 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 Gene3D G3DSA:2.40.50.140 567 673 4.7E-36 T 23-10-2018 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 7 531 1.8E-173 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 Pfam PF01588 Putative tRNA binding domain 581 671 2.9E-28 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 Gene3D G3DSA:3.40.50.620 7 373 2.7E-138 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 Pfam PF08264 Anticodon-binding domain of tRNA 409 535 7.4E-9 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 Gene3D G3DSA:1.10.730.10 374 542 1.0E-38 T 23-10-2018 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 SUPERFAMILY SSF50249 571 672 3.43E-31 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 Gene3D G3DSA:2.20.28.20 140 174 2.7E-138 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 SUPERFAMILY SSF47323 379 530 2.62E-36 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 1.2E-26 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 PRINTS PR01041 Methionyl-tRNA synthetase signature 378 389 1.2E-26 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 PRINTS PR01041 Methionyl-tRNA synthetase signature 284 299 1.2E-26 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 PRINTS PR01041 Methionyl-tRNA synthetase signature 248 259 1.2E-26 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 1.2E-26 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 1.2E-26 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 SUPERFAMILY SSF57770 140 174 2.62E-6 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_0726 aaf1530a30c9641d0b7f537b427a7a08 673 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 543 672 3.0E-41 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Mlab_1664 9f0207bfc158a6b6944ecf772aaf62cb 300 Gene3D G3DSA:3.40.50.10800 85 296 4.7E-108 T 23-10-2018 Mlab_1664 9f0207bfc158a6b6944ecf772aaf62cb 300 Pfam PF02445 Quinolinate synthetase A protein 5 296 9.3E-103 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Mlab_1664 9f0207bfc158a6b6944ecf772aaf62cb 300 Gene3D G3DSA:3.40.50.10800 171 254 4.7E-108 T 23-10-2018 Mlab_1664 9f0207bfc158a6b6944ecf772aaf62cb 300 Gene3D G3DSA:3.40.50.10800 5 279 4.7E-108 T 23-10-2018 Mlab_1664 9f0207bfc158a6b6944ecf772aaf62cb 300 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 2 297 2.7E-97 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Mlab_1664 9f0207bfc158a6b6944ecf772aaf62cb 300 SUPERFAMILY SSF142754 2 296 1.44E-103 T 23-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Mlab_0058 85417c8a21c8b2ceb04d4e4a048533a0 181 Pfam PF02441 Flavoprotein 2 160 6.8E-29 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 Mlab_0058 85417c8a21c8b2ceb04d4e4a048533a0 181 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 2 181 34.362 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like Mlab_0058 85417c8a21c8b2ceb04d4e4a048533a0 181 Gene3D G3DSA:3.40.50.1950 2 181 4.3E-69 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Mlab_0058 85417c8a21c8b2ceb04d4e4a048533a0 181 SUPERFAMILY SSF52507 2 180 7.19E-55 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Mlab_0058 85417c8a21c8b2ceb04d4e4a048533a0 181 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 3 179 1.1E-61 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like Mlab_1117 9c85702b85ee67bca99228cb728b9a41 627 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 292 1.8E-25 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_1117 9c85702b85ee67bca99228cb728b9a41 627 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 425 626 7.4E-28 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_1117 9c85702b85ee67bca99228cb728b9a41 627 Gene3D G3DSA:1.10.3720.10 400 626 6.0E-35 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1117 9c85702b85ee67bca99228cb728b9a41 627 Gene3D G3DSA:1.10.3720.10 63 297 7.0E-37 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1117 9c85702b85ee67bca99228cb728b9a41 627 SUPERFAMILY SSF161098 18 290 1.87E-36 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1117 9c85702b85ee67bca99228cb728b9a41 627 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 14 294 5.1E-88 T 23-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 Mlab_1117 9c85702b85ee67bca99228cb728b9a41 627 SUPERFAMILY SSF161098 367 614 1.57E-35 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1117 9c85702b85ee67bca99228cb728b9a41 627 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 356 623 2.5E-90 T 23-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 Mlab_0337 ad9c61c5f7180f9c6719612e87f2a582 183 ProSitePatterns PS01318 TsaA-like domain signature. 104 115 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site Mlab_0337 ad9c61c5f7180f9c6719612e87f2a582 183 SUPERFAMILY SSF118196 26 170 1.57E-50 T 23-10-2018 IPR036413 YaeB-like superfamily Mlab_0337 ad9c61c5f7180f9c6719612e87f2a582 183 Pfam PF01980 Uncharacterised protein family UPF0066 44 156 2.9E-37 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain Mlab_0337 ad9c61c5f7180f9c6719612e87f2a582 183 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 27 162 1.0E-35 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain Mlab_0337 ad9c61c5f7180f9c6719612e87f2a582 183 Gene3D G3DSA:2.40.30.70 28 171 6.4E-46 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily Mlab_0345 340d9045030a786c5292fdfd7b409539 453 Gene3D G3DSA:2.40.50.600 364 433 2.7E-19 T 23-10-2018 Mlab_0345 340d9045030a786c5292fdfd7b409539 453 SUPERFAMILY SSF102114 134 371 2.35E-31 T 23-10-2018 Mlab_0345 340d9045030a786c5292fdfd7b409539 453 Pfam PF04055 Radical SAM superfamily 145 259 3.7E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0345 340d9045030a786c5292fdfd7b409539 453 Gene3D G3DSA:3.20.20.70 77 363 1.9E-117 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0345 340d9045030a786c5292fdfd7b409539 453 Pfam PF13394 4Fe-4S single cluster domain 142 213 7.6E-5 T 23-10-2018 Mlab_0345 340d9045030a786c5292fdfd7b409539 453 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 36 448 2.5E-236 T 23-10-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 Mlab_0345 340d9045030a786c5292fdfd7b409539 453 TIGRFAM TIGR00238 TIGR00238: KamA family protein 36 357 9.5E-108 T 23-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase Mlab_0345 340d9045030a786c5292fdfd7b409539 453 PIRSF PIRSF004911 6 420 7.7E-152 T 23-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase Mlab_0345 340d9045030a786c5292fdfd7b409539 453 Pfam PF12544 Lysine-2,3-aminomutase 336 451 5.8E-42 T 23-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain Mlab_1488 e1114c13071617b2b9fbb626f56862cb 212 Gene3D G3DSA:1.10.10.460 157 204 2.4E-21 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 Mlab_1488 e1114c13071617b2b9fbb626f56862cb 212 Hamap MF_00052_A Ribonuclease HII [rnhB]. 2 201 32.299 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 Mlab_1488 e1114c13071617b2b9fbb626f56862cb 212 Gene3D G3DSA:3.30.420.10 2 156 3.2E-44 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Mlab_1488 e1114c13071617b2b9fbb626f56862cb 212 Pfam PF01351 Ribonuclease HII 4 196 3.7E-45 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain Mlab_1488 e1114c13071617b2b9fbb626f56862cb 212 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 3 201 4.7E-62 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 Mlab_1488 e1114c13071617b2b9fbb626f56862cb 212 SUPERFAMILY SSF53098 1 202 2.73E-48 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily Mlab_0005 bd182db5a71067dcf528e3162607707b 694 PIRSF PIRSF001265 1 693 2.9E-269 T 23-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Mlab_0005 bd182db5a71067dcf528e3162607707b 694 Pfam PF03030 Inorganic H+ pyrophosphatase 12 687 4.2E-273 T 23-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Mlab_0005 bd182db5a71067dcf528e3162607707b 694 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 1 692 25.531 T 23-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Mlab_0005 bd182db5a71067dcf528e3162607707b 694 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 5 691 4.5E-259 T 23-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Mlab_1119 8c46bb92b7262d5140b1c953c22c1086 333 Pfam PF01895 PhoU domain 250 325 2.8E-5 T 23-10-2018 IPR026022 PhoU domain Mlab_1119 8c46bb92b7262d5140b1c953c22c1086 333 Pfam PF01895 PhoU domain 140 230 9.8E-17 T 23-10-2018 IPR026022 PhoU domain Mlab_1119 8c46bb92b7262d5140b1c953c22c1086 333 SUPERFAMILY SSF109755 129 328 1.88E-32 T 23-10-2018 Mlab_1119 8c46bb92b7262d5140b1c953c22c1086 333 Gene3D G3DSA:1.20.58.220 134 239 8.5E-23 T 23-10-2018 IPR038078 PhoU-like domain superfamily Mlab_1119 8c46bb92b7262d5140b1c953c22c1086 333 SMART SM00966 8 54 1.6E-4 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Mlab_1526 f4863ea19dece82cea2b9801f1748f90 182 SUPERFAMILY SSF109604 39 167 6.77E-18 T 23-10-2018 Mlab_1526 f4863ea19dece82cea2b9801f1748f90 182 Pfam PF01966 HD domain 53 155 9.9E-6 T 23-10-2018 IPR006674 HD domain Mlab_1526 f4863ea19dece82cea2b9801f1748f90 182 Gene3D G3DSA:1.10.3210.10 25 177 7.6E-9 T 23-10-2018 Mlab_1526 f4863ea19dece82cea2b9801f1748f90 182 SMART SM00471 49 168 0.0025 T 23-10-2018 IPR003607 HD/PDEase domain Mlab_1526 f4863ea19dece82cea2b9801f1748f90 182 TIGRFAM TIGR00277 HDIG: HDIG domain 51 88 2.3E-8 T 23-10-2018 IPR006675 HDIG domain Mlab_0335 392671bbe133bd0f48769c83a3d09309 533 Pfam PF00144 Beta-lactamase 63 387 1.2E-64 T 23-10-2018 IPR001466 Beta-lactamase-related Mlab_0335 392671bbe133bd0f48769c83a3d09309 533 Gene3D G3DSA:3.40.710.10 49 386 1.6E-86 T 23-10-2018 Mlab_0335 392671bbe133bd0f48769c83a3d09309 533 SUPERFAMILY SSF56601 59 392 1.11E-79 T 23-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Mlab_1511 69b43dea33c5e023065794776723e1e0 340 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 191 206 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 Pfam PF08271 TFIIB zinc-binding 43 84 2.0E-18 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type Mlab_1511 69b43dea33c5e023065794776723e1e0 340 PRINTS PR00685 Transcription initiation factor IIB signature 199 218 1.5E-66 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 PRINTS PR00685 Transcription initiation factor IIB signature 78 91 1.5E-66 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 PRINTS PR00685 Transcription initiation factor IIB signature 252 270 1.5E-66 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 PRINTS PR00685 Transcription initiation factor IIB signature 91 112 1.5E-66 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 PRINTS PR00685 Transcription initiation factor IIB signature 56 76 1.5E-66 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 PRINTS PR00685 Transcription initiation factor IIB signature 286 302 1.5E-66 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 PRINTS PR00685 Transcription initiation factor IIB signature 318 332 1.5E-66 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 PRINTS PR00685 Transcription initiation factor IIB signature 225 240 1.5E-66 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 SUPERFAMILY SSF47954 151 244 8.99E-30 T 23-10-2018 IPR036915 Cyclin-like superfamily Mlab_1511 69b43dea33c5e023065794776723e1e0 340 Gene3D G3DSA:1.10.472.10 248 340 1.8E-28 T 23-10-2018 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 285 300 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 SUPERFAMILY SSF47954 248 338 8.84E-31 T 23-10-2018 IPR036915 Cyclin-like superfamily Mlab_1511 69b43dea33c5e023065794776723e1e0 340 SMART SM00385 251 332 4.0E-10 T 23-10-2018 IPR013763 Cyclin-like Mlab_1511 69b43dea33c5e023065794776723e1e0 340 SMART SM00385 157 238 3.4E-14 T 23-10-2018 IPR013763 Cyclin-like Mlab_1511 69b43dea33c5e023065794776723e1e0 340 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 38 338 46.876 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea Mlab_1511 69b43dea33c5e023065794776723e1e0 340 Gene3D G3DSA:1.10.472.170 42 240 9.0E-72 T 23-10-2018 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 Pfam PF00382 Transcription factor TFIIB repeat 253 323 4.0E-20 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 Pfam PF00382 Transcription factor TFIIB repeat 160 229 8.8E-22 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 Mlab_1511 69b43dea33c5e023065794776723e1e0 340 SUPERFAMILY SSF57783 42 87 2.38E-17 T 23-10-2018 Mlab_0996 2428335b0a307416d2a81dd23c4d5ae9 420 Gene3D G3DSA:3.20.20.70 191 406 9.9E-57 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0996 2428335b0a307416d2a81dd23c4d5ae9 420 SUPERFAMILY SSF51366 112 409 1.8E-46 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_0996 2428335b0a307416d2a81dd23c4d5ae9 420 SMART SM00934 191 402 1.1E-40 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0996 2428335b0a307416d2a81dd23c4d5ae9 420 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 20 177 1.2E-68 T 23-10-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 Mlab_0996 2428335b0a307416d2a81dd23c4d5ae9 420 SUPERFAMILY SSF54211 17 180 3.57E-59 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_0996 2428335b0a307416d2a81dd23c4d5ae9 420 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 191 401 1.5E-21 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0996 2428335b0a307416d2a81dd23c4d5ae9 420 Gene3D G3DSA:3.30.230.60 15 180 1.9E-57 T 23-10-2018 IPR037075 Formaldehyde-activating enzyme superfamily GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 Mlab_0996 2428335b0a307416d2a81dd23c4d5ae9 420 Hamap MF_01268 Bifunctional enzyme Fae/Hps [fae-hps]. 1 420 228.182 T 23-10-2018 IPR020868 Bifunctional enzyme Fae/Hps GO:0016051|GO:0016832|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 Mlab_0996 2428335b0a307416d2a81dd23c4d5ae9 420 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 21 178 2.7E-61 T 23-10-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 Mlab_0929 84d69e0fa549887b442ea9b03adf787f 959 SUPERFAMILY SSF56317 662 929 3.03E-7 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Mlab_0801 2910132fc8c0444bc11f5114b1f38ebc 366 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 3 362 4.8E-141 T 23-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type Mlab_0801 2910132fc8c0444bc11f5114b1f38ebc 366 SUPERFAMILY SSF102114 120 346 2.35E-36 T 23-10-2018 Mlab_0801 2910132fc8c0444bc11f5114b1f38ebc 366 SMART SM00729 139 351 4.0E-33 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_0801 2910132fc8c0444bc11f5114b1f38ebc 366 Gene3D G3DSA:3.80.30.20 137 359 1.2E-37 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Mlab_0801 2910132fc8c0444bc11f5114b1f38ebc 366 Pfam PF04055 Radical SAM superfamily 143 310 5.0E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0801 2910132fc8c0444bc11f5114b1f38ebc 366 Gene3D G3DSA:3.40.50.280 4 111 7.2E-13 T 23-10-2018 Mlab_0801 2910132fc8c0444bc11f5114b1f38ebc 366 Pfam PF02310 B12 binding domain 49 98 4.6E-8 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Mlab_0801 2910132fc8c0444bc11f5114b1f38ebc 366 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 143 163 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Mlab_1134 29573e68689462dc14f4bbb7afee7ac1 527 SUPERFAMILY SSF52540 1 272 1.51E-112 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1134 29573e68689462dc14f4bbb7afee7ac1 527 Gene3D G3DSA:3.40.50.300 1 287 3.0E-126 T 23-10-2018 Mlab_1134 29573e68689462dc14f4bbb7afee7ac1 527 SUPERFAMILY SSF52317 291 525 4.44E-68 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_1134 29573e68689462dc14f4bbb7afee7ac1 527 Gene3D G3DSA:3.40.50.880 288 527 4.4E-91 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_1134 29573e68689462dc14f4bbb7afee7ac1 527 Pfam PF00117 Glutamine amidotransferase class-I 302 519 1.5E-53 T 23-10-2018 IPR017926 Glutamine amidotransferase Mlab_1134 29573e68689462dc14f4bbb7afee7ac1 527 Hamap MF_01227 CTP synthase [pyrG]. 1 524 44.898 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Mlab_1134 29573e68689462dc14f4bbb7afee7ac1 527 TIGRFAM TIGR00337 PyrG: CTP synthase 1 519 4.7E-215 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Mlab_1134 29573e68689462dc14f4bbb7afee7ac1 527 Pfam PF06418 CTP synthase N-terminus 2 271 8.4E-119 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Mlab_0775 5054df3584aa6ce5773b12ded4480acb 281 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 108 1.1E-17 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Mlab_0775 5054df3584aa6ce5773b12ded4480acb 281 Pfam PF00156 Phosphoribosyl transferase domain 150 236 1.4E-11 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Mlab_0775 5054df3584aa6ce5773b12ded4480acb 281 SUPERFAMILY SSF53271 72 264 4.3E-34 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like Mlab_0775 5054df3584aa6ce5773b12ded4480acb 281 Gene3D G3DSA:3.40.50.2020 146 270 8.3E-27 T 23-10-2018 Mlab_0775 5054df3584aa6ce5773b12ded4480acb 281 Gene3D G3DSA:3.40.50.2020 1 145 4.6E-40 T 23-10-2018 Mlab_0775 5054df3584aa6ce5773b12ded4480acb 281 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 280 1.4E-75 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Mlab_0775 5054df3584aa6ce5773b12ded4480acb 281 SMART SM01400 1 109 5.1E-30 T 23-10-2018 Mlab_0163 2ab78291237d0ba28da4d8027bd9d3de 377 Gene3D G3DSA:3.40.50.1980 13 133 7.9E-24 T 23-10-2018 Mlab_0163 2ab78291237d0ba28da4d8027bd9d3de 377 SUPERFAMILY SSF53807 4 369 3.11E-53 T 23-10-2018 Mlab_0163 2ab78291237d0ba28da4d8027bd9d3de 377 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 13 184 3.7E-24 T 23-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 Mlab_0163 2ab78291237d0ba28da4d8027bd9d3de 377 Gene3D G3DSA:3.40.50.1980 134 209 1.1E-5 T 23-10-2018 Mlab_0716 6429f6911d96d35a4371d62db00d3d03 305 Pfam PF00005 ABC transporter 25 176 6.2E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0716 6429f6911d96d35a4371d62db00d3d03 305 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 227 299 2.3E-10 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Mlab_0716 6429f6911d96d35a4371d62db00d3d03 305 SUPERFAMILY SSF52540 1 245 1.0E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0716 6429f6911d96d35a4371d62db00d3d03 305 Gene3D G3DSA:3.40.50.300 1 302 1.7E-73 T 23-10-2018 Mlab_0716 6429f6911d96d35a4371d62db00d3d03 305 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 282 4.9E-7 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Mlab_0716 6429f6911d96d35a4371d62db00d3d03 305 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_0716 6429f6911d96d35a4371d62db00d3d03 305 SMART SM00382 33 227 5.5E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0184 de1bf6e5bf0d92ae82e15f1d66370131 198 Pfam PF04893 Yip1 domain 10 165 1.1E-20 T 23-10-2018 IPR006977 Yip1 domain GO:0016020 Mlab_0800 36bc21b753233327b50c4666f6f80cfb 131 PIRSF PIRSF004966 1 129 2.4E-45 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative Mlab_0800 36bc21b753233327b50c4666f6f80cfb 131 Pfam PF01989 Protein of unknown function DUF126 24 103 1.9E-37 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative Mlab_0800 36bc21b753233327b50c4666f6f80cfb 131 Gene3D G3DSA:3.50.30.10 1 130 8.1E-46 T 23-10-2018 Mlab_0800 36bc21b753233327b50c4666f6f80cfb 131 Hamap MF_00078 UPF0107 protein . 2 128 32.533 T 23-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative Mlab_0800 36bc21b753233327b50c4666f6f80cfb 131 SUPERFAMILY SSF52016 1 126 1.57E-42 T 23-10-2018 Mlab_0994 6d7e4291ca28e08b6c365152d46a7b33 369 Pfam PF00155 Aminotransferase class I and II 28 364 7.0E-60 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Mlab_0994 6d7e4291ca28e08b6c365152d46a7b33 369 Gene3D G3DSA:3.90.1150.10 25 363 1.2E-110 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_0994 6d7e4291ca28e08b6c365152d46a7b33 369 Gene3D G3DSA:3.40.640.10 57 274 1.2E-110 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_0994 6d7e4291ca28e08b6c365152d46a7b33 369 SUPERFAMILY SSF53383 3 368 4.3E-100 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_1379 f1e28dc5e4f55df9623b6145327ea375 242 Gene3D G3DSA:3.20.20.150 16 241 3.0E-43 T 23-10-2018 Mlab_1379 f1e28dc5e4f55df9623b6145327ea375 242 SUPERFAMILY SSF51658 4 232 1.57E-32 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily Mlab_1379 f1e28dc5e4f55df9623b6145327ea375 242 Pfam PF01261 Xylose isomerase-like TIM barrel 47 205 8.5E-15 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Mlab_0714 d1a7b097279895d64cf9d28e3afe0a37 410 Pfam PF03600 Citrate transporter 15 335 5.9E-29 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 Mlab_1187 3d6df99042d217a377c72ce84939f3ff 387 Pfam PF13353 4Fe-4S single cluster domain 90 153 1.1E-5 T 23-10-2018 Mlab_1187 3d6df99042d217a377c72ce84939f3ff 387 SUPERFAMILY SSF102114 81 373 4.12E-44 T 23-10-2018 Mlab_1187 3d6df99042d217a377c72ce84939f3ff 387 Gene3D G3DSA:3.20.20.70 83 353 3.2E-35 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1187 3d6df99042d217a377c72ce84939f3ff 387 Pfam PF04055 Radical SAM superfamily 88 240 3.1E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0557 939fe83e926bf77794c7956b4e32d280 319 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 3 304 1.4E-125 T 23-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 Mlab_0557 939fe83e926bf77794c7956b4e32d280 319 SUPERFAMILY SSF100950 3 303 5.76E-90 T 23-10-2018 IPR037171 NagB/RpiA transferase-like Mlab_0557 939fe83e926bf77794c7956b4e32d280 319 Pfam PF01008 Initiation factor 2 subunit family 14 291 4.7E-84 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 Mlab_0557 939fe83e926bf77794c7956b4e32d280 319 Gene3D G3DSA:3.40.50.10470 106 302 3.9E-72 T 23-10-2018 Mlab_0557 939fe83e926bf77794c7956b4e32d280 319 Gene3D G3DSA:1.20.120.420 1 105 1.0E-23 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Mlab_0557 939fe83e926bf77794c7956b4e32d280 319 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 3 291 1.9E-79 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Mlab_0349 b622870cbd8f616a975d36c81dbacda8 367 SUPERFAMILY SSF102114 4 307 1.45E-31 T 23-10-2018 Mlab_0349 b622870cbd8f616a975d36c81dbacda8 367 Pfam PF13353 4Fe-4S single cluster domain 7 121 3.4E-6 T 23-10-2018 Mlab_0349 b622870cbd8f616a975d36c81dbacda8 367 Gene3D G3DSA:3.20.20.70 2 344 6.0E-35 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0349 b622870cbd8f616a975d36c81dbacda8 367 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 245 314 4.6E-8 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain Mlab_0349 b622870cbd8f616a975d36c81dbacda8 367 TIGRFAM TIGR04084 rSAM_AF0577: putative peptide-modifying radical SAM enzyme, AF0577 family 6 367 8.3E-79 T 23-10-2018 IPR023819 Peptide-modifying radical SAM enzyme putative, AF0577 Mlab_0311 43f1e6e8acef2e944aedab92ca836db1 102 PIRSF PIRSF000077 8 102 1.6E-27 T 23-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Mlab_0311 43f1e6e8acef2e944aedab92ca836db1 102 Gene3D G3DSA:3.40.30.10 11 102 4.3E-25 T 23-10-2018 Mlab_0311 43f1e6e8acef2e944aedab92ca836db1 102 SUPERFAMILY SSF52833 15 101 1.95E-27 T 23-10-2018 IPR036249 Thioredoxin-like superfamily Mlab_0311 43f1e6e8acef2e944aedab92ca836db1 102 Pfam PF00085 Thioredoxin 15 99 1.7E-21 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 Mlab_0311 43f1e6e8acef2e944aedab92ca836db1 102 PRINTS PR00421 Thioredoxin family signature 26 35 6.5E-5 T 23-10-2018 Mlab_0311 43f1e6e8acef2e944aedab92ca836db1 102 PRINTS PR00421 Thioredoxin family signature 18 26 6.5E-5 T 23-10-2018 Mlab_0311 43f1e6e8acef2e944aedab92ca836db1 102 PRINTS PR00421 Thioredoxin family signature 66 77 6.5E-5 T 23-10-2018 Mlab_1195 66f65ac1b9f8ffbf7f63dff88ed54239 145 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 15 130 2.0E-41 T 23-10-2018 IPR026350 GxxExxY protein Mlab_1195 66f65ac1b9f8ffbf7f63dff88ed54239 145 Pfam PF13366 PD-(D/E)XK nuclease superfamily 15 129 6.0E-40 T 23-10-2018 IPR026350 GxxExxY protein Mlab_1545 76e9375f2d79643c2a4bf1335f764fe8 365 SUPERFAMILY SSF53383 2 364 1.9E-91 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_1545 76e9375f2d79643c2a4bf1335f764fe8 365 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 13 365 54.35 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Mlab_1545 76e9375f2d79643c2a4bf1335f764fe8 365 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 8 364 8.2E-158 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Mlab_1545 76e9375f2d79643c2a4bf1335f764fe8 365 Gene3D G3DSA:3.90.1150.10 4 358 1.8E-112 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_1545 76e9375f2d79643c2a4bf1335f764fe8 365 Gene3D G3DSA:3.40.640.10 37 282 1.8E-112 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_1545 76e9375f2d79643c2a4bf1335f764fe8 365 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 59 305 6.9E-35 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 Mlab_1545 76e9375f2d79643c2a4bf1335f764fe8 365 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 218 239 - T 23-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 Mlab_0100 c95c49a76c3082111a3b60f459d4b0fe 174 SUPERFAMILY SSF53137 3 160 2.62E-54 T 23-10-2018 Mlab_0100 c95c49a76c3082111a3b60f459d4b0fe 174 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 103 131 7.6E-7 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0100 c95c49a76c3082111a3b60f459d4b0fe 174 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 93 5.1E-24 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0100 c95c49a76c3082111a3b60f459d4b0fe 174 Gene3D G3DSA:3.30.420.100 1 173 3.1E-56 T 23-10-2018 Mlab_0100 c95c49a76c3082111a3b60f459d4b0fe 174 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 169 33.568 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1313 51cb7a09ffae4ee4e964b87ffc25e388 361 SUPERFAMILY SSF48371 3 328 1.6E-33 T 23-10-2018 IPR016024 Armadillo-type fold Mlab_1313 51cb7a09ffae4ee4e964b87ffc25e388 361 Pfam PF13646 HEAT repeats 72 152 4.1E-9 T 23-10-2018 Mlab_1313 51cb7a09ffae4ee4e964b87ffc25e388 361 Pfam PF13646 HEAT repeats 271 342 2.0E-14 T 23-10-2018 Mlab_1313 51cb7a09ffae4ee4e964b87ffc25e388 361 SMART SM00567 E-Z type HEAT repeats 110 139 0.17 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Mlab_1313 51cb7a09ffae4ee4e964b87ffc25e388 361 SMART SM00567 E-Z type HEAT repeats 282 311 1.2E-7 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Mlab_1313 51cb7a09ffae4ee4e964b87ffc25e388 361 SMART SM00567 E-Z type HEAT repeats 313 342 4.2E-4 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Mlab_1313 51cb7a09ffae4ee4e964b87ffc25e388 361 SMART SM00567 E-Z type HEAT repeats 141 170 93.0 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Mlab_1313 51cb7a09ffae4ee4e964b87ffc25e388 361 Gene3D G3DSA:1.25.10.10 222 361 1.1E-23 T 23-10-2018 IPR011989 Armadillo-like helical Mlab_1313 51cb7a09ffae4ee4e964b87ffc25e388 361 Gene3D G3DSA:1.25.10.10 67 221 3.4E-20 T 23-10-2018 IPR011989 Armadillo-like helical Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 Pfam PF00815 Histidinol dehydrogenase 6 401 3.1E-164 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 Gene3D G3DSA:3.40.50.1980 209 324 3.6E-120 T 23-10-2018 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 PIRSF PIRSF000099 1 403 1.6E-159 T 23-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 Gene3D G3DSA:3.40.50.1980 10 207 3.6E-120 T 23-10-2018 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 SUPERFAMILY SSF53720 6 401 4.51E-77 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 205 237 - T 23-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 402 40.002 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 PRINTS PR00083 Histidinol dehydrogenase signature 146 172 1.1E-88 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 PRINTS PR00083 Histidinol dehydrogenase signature 227 246 1.1E-88 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 PRINTS PR00083 Histidinol dehydrogenase signature 176 201 1.1E-88 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 PRINTS PR00083 Histidinol dehydrogenase signature 205 226 1.1E-88 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 PRINTS PR00083 Histidinol dehydrogenase signature 336 354 1.1E-88 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 PRINTS PR00083 Histidinol dehydrogenase signature 13 37 1.1E-88 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 PRINTS PR00083 Histidinol dehydrogenase signature 115 141 1.1E-88 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 PRINTS PR00083 Histidinol dehydrogenase signature 295 320 1.1E-88 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_0461 4f0c94f3142a7de76ee0c9baf6b17d0c 403 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 13 401 2.9E-159 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Mlab_1629 696ca91ea948311974aaf7c3c08d7fc5 222 Pfam PF13412 Winged helix-turn-helix DNA-binding 26 56 7.0E-5 T 23-10-2018 Mlab_1629 696ca91ea948311974aaf7c3c08d7fc5 222 Gene3D G3DSA:1.10.10.10 2 89 2.5E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1629 696ca91ea948311974aaf7c3c08d7fc5 222 SUPERFAMILY SSF46785 11 88 1.73E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1629 696ca91ea948311974aaf7c3c08d7fc5 222 Pfam PF01982 Domain of unknown function DUF120 101 221 5.9E-44 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 Mlab_1629 696ca91ea948311974aaf7c3c08d7fc5 222 SUPERFAMILY SSF82114 94 221 4.58E-46 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 Mlab_1629 696ca91ea948311974aaf7c3c08d7fc5 222 Hamap MF_01285 Riboflavin kinase [ribK]. 95 221 24.954 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 Mlab_1629 696ca91ea948311974aaf7c3c08d7fc5 222 Gene3D G3DSA:2.40.30.30 91 222 2.2E-45 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 Mlab_0202 df0ddd97c88fbf9c2499678ebbbffd36 467 PIRSF PIRSF000485 1 461 1.6E-165 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Mlab_0202 df0ddd97c88fbf9c2499678ebbbffd36 467 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 444 44.405 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Mlab_0202 df0ddd97c88fbf9c2499678ebbbffd36 467 Gene3D G3DSA:3.60.20.10 2 445 3.4E-146 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Mlab_0202 df0ddd97c88fbf9c2499678ebbbffd36 467 Pfam PF13537 Glutamine amidotransferase domain 82 202 9.3E-20 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain Mlab_0202 df0ddd97c88fbf9c2499678ebbbffd36 467 Pfam PF00156 Phosphoribosyl transferase domain 270 373 1.9E-6 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Mlab_0202 df0ddd97c88fbf9c2499678ebbbffd36 467 SUPERFAMILY SSF56235 2 245 1.37E-64 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Mlab_0202 df0ddd97c88fbf9c2499678ebbbffd36 467 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 445 1.6E-152 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Mlab_0202 df0ddd97c88fbf9c2499678ebbbffd36 467 SUPERFAMILY SSF53271 238 451 1.97E-65 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like Mlab_0202 df0ddd97c88fbf9c2499678ebbbffd36 467 Gene3D G3DSA:3.40.50.2020 263 427 3.4E-146 T 23-10-2018 Mlab_1146 c96b1820c4bba445b864309ec000f308 184 Gene3D G3DSA:3.40.470.10 29 182 2.7E-13 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Mlab_1146 c96b1820c4bba445b864309ec000f308 184 SUPERFAMILY SSF52141 49 123 1.41E-7 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Mlab_1146 c96b1820c4bba445b864309ec000f308 184 Pfam PF03167 Uracil DNA glycosylase superfamily 48 126 5.0E-7 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 Gene3D G3DSA:3.30.420.40 103 247 3.0E-68 T 23-10-2018 Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 899 981 2.8E-12 T 23-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 11 260 1.7E-39 T 23-10-2018 IPR008275 CoA enzyme activase Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 326 578 5.6E-38 T 23-10-2018 IPR008275 CoA enzyme activase Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 12 223 1.9E-26 T 23-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 326 580 9.0E-37 T 23-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 Gene3D G3DSA:3.30.420.40 326 580 2.2E-80 T 23-10-2018 Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 SUPERFAMILY SSF53067 325 580 7.86E-53 T 23-10-2018 Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 Gene3D G3DSA:3.30.420.40 420 563 2.2E-80 T 23-10-2018 Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 668 885 5.6E-72 T 23-10-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 SUPERFAMILY SSF53067 11 260 2.32E-52 T 23-10-2018 Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 Gene3D G3DSA:3.30.420.40 12 260 3.0E-68 T 23-10-2018 Mlab_1387 5089c833d88bf91517bffda9415b61ca 981 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 25 33 - T 23-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Mlab_0338 d3705080249a14fb48cb3762bfa1a289 249 Gene3D G3DSA:3.30.390.100 18 218 1.2E-45 T 23-10-2018 Mlab_0338 d3705080249a14fb48cb3762bfa1a289 249 Pfam PF13938 Putative heavy-metal chelation 10 93 1.0E-21 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 Mlab_0338 d3705080249a14fb48cb3762bfa1a289 249 Pfam PF04016 Putative heavy-metal chelation 104 236 1.1E-42 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain Mlab_0338 d3705080249a14fb48cb3762bfa1a289 249 SUPERFAMILY SSF159713 6 238 1.44E-63 T 23-10-2018 Mlab_0338 d3705080249a14fb48cb3762bfa1a289 249 Gene3D G3DSA:3.40.50.11590 104 215 1.2E-45 T 23-10-2018 Mlab_1457 03b34d1750338d47dfa6074ac015430a 428 PIRSF PIRSF006444 1 428 1.0E-181 T 23-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 Mlab_1457 03b34d1750338d47dfa6074ac015430a 428 Gene3D G3DSA:3.40.50.12780 1 321 1.4E-120 T 23-10-2018 Mlab_1457 03b34d1750338d47dfa6074ac015430a 428 Pfam PF14535 AMP-binding enzyme C-terminal domain 330 426 1.1E-30 T 23-10-2018 IPR028154 AMP-dependent ligase, C-terminal Mlab_1457 03b34d1750338d47dfa6074ac015430a 428 Gene3D G3DSA:3.30.300.30 322 427 5.8E-33 T 23-10-2018 Mlab_1457 03b34d1750338d47dfa6074ac015430a 428 SUPERFAMILY SSF56801 45 394 6.28E-60 T 23-10-2018 Mlab_1457 03b34d1750338d47dfa6074ac015430a 428 Pfam PF00501 AMP-binding enzyme 80 281 5.9E-17 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Mlab_1359 bf25ea56691f7fa5ea314c87e288cf83 278 SUPERFAMILY SSF48452 4 145 5.69E-20 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1359 bf25ea56691f7fa5ea314c87e288cf83 278 SUPERFAMILY SSF48452 190 258 1.04E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1359 bf25ea56691f7fa5ea314c87e288cf83 278 SMART SM00028 227 260 1.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1359 bf25ea56691f7fa5ea314c87e288cf83 278 SMART SM00028 35 68 1.2 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1359 bf25ea56691f7fa5ea314c87e288cf83 278 SMART SM00028 1 34 16.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1359 bf25ea56691f7fa5ea314c87e288cf83 278 SMART SM00028 192 225 0.99 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1359 bf25ea56691f7fa5ea314c87e288cf83 278 Gene3D G3DSA:1.25.40.10 1 169 1.5E-18 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1359 bf25ea56691f7fa5ea314c87e288cf83 278 Gene3D G3DSA:1.25.40.10 190 276 1.5E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_1359 bf25ea56691f7fa5ea314c87e288cf83 278 Pfam PF13181 Tetratricopeptide repeat 38 66 0.0022 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_1458 7d667ca6c39d65c742ca67cf8812b5dd 625 Gene3D G3DSA:1.20.81.30 410 517 2.9E-9 T 23-10-2018 Mlab_1458 7d667ca6c39d65c742ca67cf8812b5dd 625 Pfam PF00482 Type II secretion system (T2SS), protein F 117 243 1.1E-11 T 23-10-2018 IPR018076 Type II secretion system F domain Mlab_1458 7d667ca6c39d65c742ca67cf8812b5dd 625 Pfam PF00482 Type II secretion system (T2SS), protein F 417 542 7.7E-14 T 23-10-2018 IPR018076 Type II secretion system F domain Mlab_0533 93538389aec272e20a16660f63d38f67 167 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 10 166 1.1E-47 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 Mlab_0533 93538389aec272e20a16660f63d38f67 167 SUPERFAMILY SSF117457 4 165 8.37E-50 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 Mlab_0533 93538389aec272e20a16660f63d38f67 167 Pfam PF05683 Fumarase C-terminus 9 165 6.3E-38 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 Mlab_0533 93538389aec272e20a16660f63d38f67 167 Gene3D G3DSA:3.20.130.10 1 167 1.6E-57 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 Mlab_1399 6b02370d4970dd2ce64bb158e058880c 508 Gene3D G3DSA:3.60.120.10 11 508 2.2E-161 T 23-10-2018 IPR005801 ADC synthase GO:0009058 Mlab_1399 6b02370d4970dd2ce64bb158e058880c 508 SUPERFAMILY SSF56322 33 502 6.54E-143 T 23-10-2018 IPR005801 ADC synthase GO:0009058 Mlab_1399 6b02370d4970dd2ce64bb158e058880c 508 PRINTS PR00095 Anthranilate synthase component I signature 450 464 9.9E-24 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Mlab_1399 6b02370d4970dd2ce64bb158e058880c 508 PRINTS PR00095 Anthranilate synthase component I signature 355 368 9.9E-24 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Mlab_1399 6b02370d4970dd2ce64bb158e058880c 508 PRINTS PR00095 Anthranilate synthase component I signature 341 354 9.9E-24 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Mlab_1399 6b02370d4970dd2ce64bb158e058880c 508 PRINTS PR00095 Anthranilate synthase component I signature 435 449 9.9E-24 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Mlab_1399 6b02370d4970dd2ce64bb158e058880c 508 Pfam PF04715 Anthranilate synthase component I, N terminal region 46 182 1.6E-21 T 23-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Mlab_1399 6b02370d4970dd2ce64bb158e058880c 508 Pfam PF00425 chorismate binding enzyme 240 493 1.5E-95 T 23-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal Mlab_0708 7d84d96be5e85e25254681fa03433e4e 195 Gene3D G3DSA:3.40.1380.20 1 195 1.9E-65 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Mlab_0708 7d84d96be5e85e25254681fa03433e4e 195 ProDom PD022619 AF0103 MM1100 MJ0504 UNCHARACTERIZED SIMILAR MA4416 12 193 9.0E-66 T 23-10-2018 IPR015074 Protein of unknown function DUF1867 Mlab_0708 7d84d96be5e85e25254681fa03433e4e 195 PIRSF PIRSF016138 3 195 2.3E-65 T 23-10-2018 IPR015074 Protein of unknown function DUF1867 Mlab_0708 7d84d96be5e85e25254681fa03433e4e 195 SUPERFAMILY SSF52935 4 194 4.3E-62 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Mlab_0708 7d84d96be5e85e25254681fa03433e4e 195 Pfam PF02887 Pyruvate kinase, alpha/beta domain 21 172 4.3E-13 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Mlab_0362 22b734e79e1aaa12a9ed9d7d15154ebb 183 Pfam PF07790 Archaeal Type IV pilin, N-terminal 11 94 9.2E-6 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_0190 5dcb4ae05a12a2e9d286a999d22c44ab 60 TIGRFAM TIGR04272 cxxc_cxxc_Mbark: CxxC-x17-CxxC domain 18 54 2.8E-20 T 23-10-2018 IPR026363 CxxC-x17-CxxC domain Mlab_0980 bf13aba579cc73feaad493956d26a253 163 SUPERFAMILY SSF51161 3 161 5.41E-49 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily Mlab_0980 bf13aba579cc73feaad493956d26a253 163 Gene3D G3DSA:2.160.10.10 5 163 2.4E-60 T 23-10-2018 Mlab_0980 bf13aba579cc73feaad493956d26a253 163 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 82 115 2.1E-8 T 23-10-2018 IPR001451 Hexapeptide repeat Mlab_0980 bf13aba579cc73feaad493956d26a253 163 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 6 38 3.6E-7 T 23-10-2018 IPR001451 Hexapeptide repeat Mlab_1129 1839665717758b408f9519b482450b21 375 Gene3D G3DSA:3.40.640.10 54 290 4.3E-126 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_1129 1839665717758b408f9519b482450b21 375 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 211 248 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Mlab_1129 1839665717758b408f9519b482450b21 375 Gene3D G3DSA:3.90.1150.10 21 367 4.3E-126 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_1129 1839665717758b408f9519b482450b21 375 SUPERFAMILY SSF53383 19 373 3.85E-110 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_1129 1839665717758b408f9519b482450b21 375 PIRSF PIRSF000521 116 152 0.026 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Mlab_1129 1839665717758b408f9519b482450b21 375 PIRSF PIRSF000521 163 375 2.6E-23 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Mlab_1129 1839665717758b408f9519b482450b21 375 PIRSF PIRSF000521 2 122 1.7E-5 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Mlab_1129 1839665717758b408f9519b482450b21 375 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 17 370 1.0E-124 T 23-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Mlab_1129 1839665717758b408f9519b482450b21 375 Pfam PF00202 Aminotransferase class-III 20 370 6.4E-94 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Mlab_1739 ce668348a4f27c68b049ebfeb6e36dca 163 Pfam PF11576 Protein of unknown function (DUF3236) 7 158 3.0E-68 T 23-10-2018 IPR012019 Protein of unknown function DUF3236 Mlab_1739 ce668348a4f27c68b049ebfeb6e36dca 163 Gene3D G3DSA:1.10.287.470 1 39 2.9E-6 T 23-10-2018 Mlab_1739 ce668348a4f27c68b049ebfeb6e36dca 163 Gene3D G3DSA:3.40.50.10150 40 160 3.2E-48 T 23-10-2018 IPR010254 B12-dependent dehydratases, beta subunit Mlab_1739 ce668348a4f27c68b049ebfeb6e36dca 163 PIRSF PIRSF005018 6 160 1.9E-59 T 23-10-2018 IPR012019 Protein of unknown function DUF3236 Mlab_1064 999c78607e9744592bfdf92f79019b07 80 Gene3D G3DSA:3.30.70.100 8 72 3.1E-9 T 23-10-2018 Mlab_1064 999c78607e9744592bfdf92f79019b07 80 Pfam PF00403 Heavy-metal-associated domain 13 55 4.2E-8 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Mlab_1064 999c78607e9744592bfdf92f79019b07 80 SUPERFAMILY SSF55008 8 64 8.77E-13 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Mlab_1143 d68c522c201698ba09bcffbd67d5d684 138 Pfam PF02675 S-adenosylmethionine decarboxylase 30 136 5.5E-21 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 Mlab_1143 d68c522c201698ba09bcffbd67d5d684 138 SUPERFAMILY SSF56276 25 137 1.53E-16 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 Mlab_1143 d68c522c201698ba09bcffbd67d5d684 138 Gene3D G3DSA:3.60.90.10 22 138 8.4E-14 T 23-10-2018 Mlab_0004 2ccd7170cee51dfc1d04869554fdf2e5 471 Pfam PF01336 OB-fold nucleic acid binding domain 132 200 9.2E-7 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Mlab_0004 2ccd7170cee51dfc1d04869554fdf2e5 471 PIRSF PIRSF000803 87 471 1.1E-147 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_0004 2ccd7170cee51dfc1d04869554fdf2e5 471 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 224 415 1.0E-12 T 23-10-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 Mlab_0004 2ccd7170cee51dfc1d04869554fdf2e5 471 Gene3D G3DSA:3.60.21.10 222 467 9.6E-16 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like Mlab_0004 2ccd7170cee51dfc1d04869554fdf2e5 471 Hamap MF_00325 DNA polymerase II small subunit [polB]. 5 468 31.114 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_0004 2ccd7170cee51dfc1d04869554fdf2e5 471 SUPERFAMILY SSF56300 222 445 4.27E-20 T 23-10-2018 Mlab_1450 303646f746b280733268497166d08697 472 SMART SM00331 254 468 3.7E-44 T 23-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Mlab_1450 303646f746b280733268497166d08697 472 SUPERFAMILY SSF81606 268 467 2.88E-8 T 23-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Mlab_1450 303646f746b280733268497166d08697 472 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 281 468 4.7E-44 T 23-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Mlab_1450 303646f746b280733268497166d08697 472 Gene3D G3DSA:3.60.40.10 224 468 9.8E-61 T 23-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Mlab_0680 df5e0658cfd302cc55965ab619101ba0 279 Pfam PF01875 Memo-like protein 20 276 2.0E-58 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 Mlab_0680 df5e0658cfd302cc55965ab619101ba0 279 Gene3D G3DSA:3.40.830.10 15 279 1.9E-49 T 23-10-2018 Mlab_0680 df5e0658cfd302cc55965ab619101ba0 279 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 19 276 7.2E-72 T 23-10-2018 Mlab_0680 df5e0658cfd302cc55965ab619101ba0 279 Hamap MF_00055 MEMO1 family protein . 15 279 43.604 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 Mlab_1118 b7d7a16e3e908608e64b860578efec8b 278 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 4 276 2.2E-79 T 23-10-2018 IPR011862 Phosphate binding protein GO:0042301 Mlab_1118 b7d7a16e3e908608e64b860578efec8b 278 Pfam PF12849 PBP superfamily domain 31 263 2.6E-44 T 23-10-2018 IPR024370 PBP domain Mlab_1118 b7d7a16e3e908608e64b860578efec8b 278 Gene3D G3DSA:3.40.190.10 111 233 2.4E-89 T 23-10-2018 Mlab_1118 b7d7a16e3e908608e64b860578efec8b 278 SUPERFAMILY SSF53850 37 276 2.21E-80 T 23-10-2018 Mlab_1118 b7d7a16e3e908608e64b860578efec8b 278 Gene3D G3DSA:3.40.190.10 40 276 2.4E-89 T 23-10-2018 Mlab_1170 cc5767ef16e64980d7ff4d40fbd4bef2 333 Gene3D G3DSA:3.60.60.10 84 316 3.0E-15 T 23-10-2018 Mlab_0253 57fa911625af71e2ad3abc3989e73fdb 287 Pfam PF01882 Protein of unknown function DUF58 37 120 7.7E-12 T 23-10-2018 IPR002881 Domain of unknown function DUF58 Mlab_0253 57fa911625af71e2ad3abc3989e73fdb 287 SUPERFAMILY SSF53300 73 199 2.22E-5 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Mlab_0175 f6cfd102fefd699a624c3cba3b60593d 51 SUPERFAMILY SSF57802 1 50 3.2E-20 T 23-10-2018 Mlab_0175 f6cfd102fefd699a624c3cba3b60593d 51 PRINTS PR00163 Rubredoxin signature 32 48 8.6E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 Mlab_0175 f6cfd102fefd699a624c3cba3b60593d 51 PRINTS PR00163 Rubredoxin signature 3 19 8.6E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 Mlab_0175 f6cfd102fefd699a624c3cba3b60593d 51 ProSitePatterns PS00202 Rubredoxin signature. 32 42 - T 23-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 Mlab_0175 f6cfd102fefd699a624c3cba3b60593d 51 Gene3D G3DSA:2.20.28.10 1 51 3.4E-24 T 23-10-2018 Mlab_0175 f6cfd102fefd699a624c3cba3b60593d 51 Pfam PF00301 Rubredoxin 3 48 2.1E-20 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 Mlab_0175 f6cfd102fefd699a624c3cba3b60593d 51 PIRSF PIRSF000071 1 51 1.0E-24 T 23-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 Mlab_0129 7cde21ed9017488732d29aa993544c80 477 SUPERFAMILY SSF103365 5 477 9.55E-165 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Mlab_0129 7cde21ed9017488732d29aa993544c80 477 Gene3D G3DSA:3.90.1860.10 1 477 1.9E-192 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Mlab_0129 7cde21ed9017488732d29aa993544c80 477 Pfam PF01139 tRNA-splicing ligase RtcB 46 477 1.0E-162 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Mlab_0129 7cde21ed9017488732d29aa993544c80 477 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 46 75 - T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Mlab_0113 c2dd4be32cd1e1540773d4eec8e1e2ca 346 Pfam PF01594 AI-2E family transporter 14 325 2.1E-34 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like Mlab_0532 684ba17092e7fa2f3c905556d746ecfe 401 Pfam PF01940 Integral membrane protein DUF92 171 373 2.3E-52 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 Mlab_0532 684ba17092e7fa2f3c905556d746ecfe 401 TIGRFAM TIGR00297 TIGR00297: TIGR00297 family protein 164 394 3.7E-63 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 Mlab_0009 b6d76aa1710c83fee0e0f662ad78cfe4 417 PIRSF PIRSF033563 1 417 8.8E-111 T 23-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 Mlab_0009 b6d76aa1710c83fee0e0f662ad78cfe4 417 Pfam PF06245 Protein of unknown function (DUF1015) 4 414 4.1E-113 T 23-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 Mlab_1070 482daa3964d16640c831ec27c86ba9dc 535 Gene3D G3DSA:1.10.3860.10 124 533 7.0E-68 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Mlab_1070 482daa3964d16640c831ec27c86ba9dc 535 SUPERFAMILY SSF118215 137 512 6.41E-64 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Mlab_1070 482daa3964d16640c831ec27c86ba9dc 535 PRINTS PR00173 Glutamate-aspartate symporter signature 179 199 4.5E-5 T 23-10-2018 Mlab_1070 482daa3964d16640c831ec27c86ba9dc 535 PRINTS PR00173 Glutamate-aspartate symporter signature 478 498 4.5E-5 T 23-10-2018 Mlab_1070 482daa3964d16640c831ec27c86ba9dc 535 PRINTS PR00173 Glutamate-aspartate symporter signature 416 442 4.5E-5 T 23-10-2018 Mlab_1070 482daa3964d16640c831ec27c86ba9dc 535 Pfam PF00375 Sodium:dicarboxylate symporter family 139 512 9.9E-61 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Mlab_1686 d6b532b9474746d662fcb126d168a03f 287 Gene3D G3DSA:3.40.50.150 87 281 4.8E-39 T 23-10-2018 Mlab_1686 d6b532b9474746d662fcb126d168a03f 287 Pfam PF13847 Methyltransferase domain 140 266 1.4E-21 T 23-10-2018 IPR025714 Methyltransferase domain Mlab_1686 d6b532b9474746d662fcb126d168a03f 287 SUPERFAMILY SSF53335 110 276 1.35E-40 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0525 299bde01df858948ccf7448688284f0b 412 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 265 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Mlab_0525 299bde01df858948ccf7448688284f0b 412 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 2 412 81.644 T 23-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 Mlab_0525 299bde01df858948ccf7448688284f0b 412 Gene3D G3DSA:3.90.1150.10 5 406 8.7E-146 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_0525 299bde01df858948ccf7448688284f0b 412 Pfam PF00202 Aminotransferase class-III 28 337 1.6E-59 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Mlab_0525 299bde01df858948ccf7448688284f0b 412 Gene3D G3DSA:3.40.640.10 65 312 8.7E-146 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_0525 299bde01df858948ccf7448688284f0b 412 SUPERFAMILY SSF53383 2 409 8.74E-105 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 Gene3D G3DSA:3.30.310.10 11 176 5.8E-59 T 23-10-2018 IPR012295 TBP domain superfamily Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 100 180 2.7E-28 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 9 89 1.0E-24 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 Gene3D G3DSA:3.30.310.10 16 102 5.8E-59 T 23-10-2018 IPR012295 TBP domain superfamily Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 Hamap MF_00408 TATA-box-binding protein [tbp]. 5 186 35.627 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 131 180 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 PRINTS PR00686 Transcription initiation factor TFIID signature 127 142 5.6E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 PRINTS PR00686 Transcription initiation factor TFIID signature 146 162 5.6E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 PRINTS PR00686 Transcription initiation factor TFIID signature 35 54 5.6E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 PRINTS PR00686 Transcription initiation factor TFIID signature 11 26 5.6E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 PRINTS PR00686 Transcription initiation factor TFIID signature 54 72 5.6E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 PRINTS PR00686 Transcription initiation factor TFIID signature 102 118 5.6E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 SUPERFAMILY SSF55945 6 93 1.32E-25 T 23-10-2018 Mlab_0447 ad9f3afa1019d97b41e00b68dba73225 189 SUPERFAMILY SSF55945 94 184 2.98E-27 T 23-10-2018 Mlab_1066 f672430fab22905321a900d729242bc6 437 Gene3D G3DSA:3.30.70.470 45 190 1.5E-178 T 23-10-2018 IPR015823 Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 2 GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1066 f672430fab22905321a900d729242bc6 437 Pfam PF02241 Methyl-coenzyme M reductase beta subunit, C-terminal domain 188 437 1.1E-131 T 23-10-2018 IPR022679 Methyl-coenzyme M reductase, beta subunit, C-terminal GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1066 f672430fab22905321a900d729242bc6 437 SUPERFAMILY SSF48081 188 436 2.04E-109 T 23-10-2018 IPR008924 Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1066 f672430fab22905321a900d729242bc6 437 SUPERFAMILY SSF55088 3 186 3.37E-72 T 23-10-2018 IPR009024 Methyl-coenzyme M reductase, ferredoxin-like fold GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1066 f672430fab22905321a900d729242bc6 437 Pfam PF02783 Methyl-coenzyme M reductase beta subunit, N-terminal domain 6 185 4.2E-78 T 23-10-2018 IPR022680 Methyl-coenzyme M reductase, beta subunit, N-terminal GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1066 f672430fab22905321a900d729242bc6 437 TIGRFAM TIGR03257 met_CoM_red_bet: methyl-coenzyme M reductase, beta subunit 6 436 2.6E-181 T 23-10-2018 IPR003179 Methyl-coenzyme M reductase, beta subunit GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_1066 f672430fab22905321a900d729242bc6 437 Gene3D G3DSA:1.20.840.10 4 437 1.5E-178 T 23-10-2018 IPR008924 Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal GO:0015948|GO:0050524 KEGG: 00680+2.8.4.1 Mlab_0280 90dcc2cf20144da946ac0d9946b0f1ee 497 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 20 497 20.704 T 23-10-2018 IPR024912 Protein translocase subunit SecD, archaeal Mlab_0280 90dcc2cf20144da946ac0d9946b0f1ee 497 SUPERFAMILY SSF82866 302 483 3.66E-24 T 23-10-2018 Mlab_0280 90dcc2cf20144da946ac0d9946b0f1ee 497 Pfam PF02355 Protein export membrane protein 333 481 7.0E-11 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Mlab_0280 90dcc2cf20144da946ac0d9946b0f1ee 497 Gene3D G3DSA:1.20.1640.10 310 486 9.1E-6 T 23-10-2018 Mlab_0025 8fbdc52c568aef802f8d887970c45bc9 497 Gene3D G3DSA:3.40.50.12780 3 396 8.0E-106 T 23-10-2018 Mlab_0025 8fbdc52c568aef802f8d887970c45bc9 497 Pfam PF00501 AMP-binding enzyme 16 400 2.4E-89 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Mlab_0025 8fbdc52c568aef802f8d887970c45bc9 497 SUPERFAMILY SSF56801 18 496 1.19E-134 T 23-10-2018 Mlab_0025 8fbdc52c568aef802f8d887970c45bc9 497 Gene3D G3DSA:3.30.300.310 397 497 4.1E-27 T 23-10-2018 Mlab_0025 8fbdc52c568aef802f8d887970c45bc9 497 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 23-10-2018 IPR020845 AMP-binding, conserved site Mlab_0025 8fbdc52c568aef802f8d887970c45bc9 497 Pfam PF13193 AMP-binding enzyme C-terminal domain 409 481 8.2E-18 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Mlab_0439 114bb3d3a759a39973f65deed88b5469 310 Gene3D G3DSA:3.100.10.20 5 78 1.2E-12 T 23-10-2018 Mlab_0439 114bb3d3a759a39973f65deed88b5469 310 Pfam PF01867 CRISPR associated protein Cas1 7 279 3.2E-32 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Mlab_0439 114bb3d3a759a39973f65deed88b5469 310 Gene3D G3DSA:1.20.120.920 153 308 1.2E-23 T 23-10-2018 Mlab_0439 114bb3d3a759a39973f65deed88b5469 310 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 298 15.408 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Mlab_0439 114bb3d3a759a39973f65deed88b5469 310 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 7 295 5.4E-26 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 145 1.3E-46 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 303 35.332 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 Gene3D G3DSA:3.40.50.1370 132 289 3.9E-103 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 Gene3D G3DSA:3.40.50.1370 7 298 3.9E-103 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 298 2.2E-24 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 302 6.9E-108 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 SUPERFAMILY SSF53671 4 302 2.75E-93 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 7.6E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 7.6E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 7.6E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 290 7.6E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 PRINTS PR00101 Aspartate carbamoyltransferase signature 222 231 1.6E-35 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 1.6E-35 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 1.6E-35 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 PRINTS PR00101 Aspartate carbamoyltransferase signature 283 297 1.6E-35 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 PRINTS PR00101 Aspartate carbamoyltransferase signature 131 148 1.6E-35 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0792 b17bed1c168cc9b8a3d04a24ffe6666f 303 PRINTS PR00101 Aspartate carbamoyltransferase signature 261 266 1.6E-35 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0690 a342b4cfbc1571379d79d9300be1beb6 598 SMART SM01049 482 550 1.8 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0690 a342b4cfbc1571379d79d9300be1beb6 598 SMART SM01049 329 410 1.2E-13 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0690 a342b4cfbc1571379d79d9300be1beb6 598 Gene3D G3DSA:3.30.450.20 471 592 6.1E-8 T 23-10-2018 Mlab_0690 a342b4cfbc1571379d79d9300be1beb6 598 Pfam PF17200 Single Cache domain 2 502 584 1.8E-6 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0690 a342b4cfbc1571379d79d9300be1beb6 598 Pfam PF17200 Single Cache domain 2 346 460 1.1E-17 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0690 a342b4cfbc1571379d79d9300be1beb6 598 Gene3D G3DSA:3.30.450.20 311 470 1.7E-31 T 23-10-2018 Mlab_0428 94a6e05932ef9c1e45059901644b820e 271 SUPERFAMILY SSF111331 2 269 5.89E-65 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily Mlab_0428 94a6e05932ef9c1e45059901644b820e 271 Gene3D G3DSA:3.40.50.10330 20 269 1.3E-65 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 Mlab_0428 94a6e05932ef9c1e45059901644b820e 271 Hamap MF_00361 NAD kinase [nadK]. 1 270 28.911 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Mlab_0428 94a6e05932ef9c1e45059901644b820e 271 Gene3D G3DSA:2.60.200.30 117 248 1.3E-65 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Mlab_0428 94a6e05932ef9c1e45059901644b820e 271 Pfam PF01513 ATP-NAD kinase 51 256 4.2E-50 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Mlab_0464 d0a0ecefa31ee42ffb790f41b2033ccc 123 Pfam PF14601 DNA_binding protein, TFX, C-term 40 122 2.9E-22 T 23-10-2018 IPR029291 DNA binding protein Tfx, C-terminal Mlab_0464 d0a0ecefa31ee42ffb790f41b2033ccc 123 SUPERFAMILY SSF89915 6 122 1.96E-18 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 Mlab_0464 d0a0ecefa31ee42ffb790f41b2033ccc 123 Gene3D G3DSA:3.30.1190.10 5 123 1.8E-35 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 Mlab_0464 d0a0ecefa31ee42ffb790f41b2033ccc 123 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 2 120 1.0E-22 T 23-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 Mlab_0485 649973b2d31352fe0d7fdb4646044dd7 264 SUPERFAMILY SSF52518 11 218 1.97E-74 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_0485 649973b2d31352fe0d7fdb4646044dd7 264 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 49 196 7.2E-39 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Mlab_0485 649973b2d31352fe0d7fdb4646044dd7 264 Gene3D G3DSA:3.40.50.970 63 222 7.3E-32 T 23-10-2018 Mlab_0837 22ec85751a1873baecdec55c7f9c35fb 308 Gene3D G3DSA:3.90.25.10 175 227 1.0E-11 T 23-10-2018 Mlab_0837 22ec85751a1873baecdec55c7f9c35fb 308 Gene3D G3DSA:3.90.25.10 228 308 2.6E-26 T 23-10-2018 Mlab_0837 22ec85751a1873baecdec55c7f9c35fb 308 SUPERFAMILY SSF51735 1 304 2.94E-75 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0837 22ec85751a1873baecdec55c7f9c35fb 308 Gene3D G3DSA:3.40.50.720 2 174 7.5E-47 T 23-10-2018 Mlab_0837 22ec85751a1873baecdec55c7f9c35fb 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 235 6.6E-47 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Mlab_1164 d37432b6a7cf0dcb77f8b41fbc5c01d3 82 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 10 76 6.0E-19 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1164 d37432b6a7cf0dcb77f8b41fbc5c01d3 82 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 5 76 2.7E-30 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1164 d37432b6a7cf0dcb77f8b41fbc5c01d3 82 SUPERFAMILY SSF55287 4 77 4.84E-24 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1164 d37432b6a7cf0dcb77f8b41fbc5c01d3 82 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 4 77 21.858 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1164 d37432b6a7cf0dcb77f8b41fbc5c01d3 82 Gene3D G3DSA:3.90.940.20 1 78 5.0E-28 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Mlab_1485 de4223f229d1e0289f8433fdccbd5b29 106 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 6 101 21.022 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 Mlab_1485 de4223f229d1e0289f8433fdccbd5b29 106 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 17 92 8.8E-14 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Mlab_1485 de4223f229d1e0289f8433fdccbd5b29 106 Gene3D G3DSA:1.20.5.420 3 58 2.8E-15 T 23-10-2018 Mlab_1485 de4223f229d1e0289f8433fdccbd5b29 106 PIRSF PIRSF004878 1 106 5.8E-32 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 Mlab_1485 de4223f229d1e0289f8433fdccbd5b29 106 SUPERFAMILY SSF82919 55 100 7.85E-5 T 23-10-2018 IPR036174 Zinc finger, Sec23/Sec24-type superfamily GO:0006886|GO:0006888|GO:0008270|GO:0030127 Mlab_1485 de4223f229d1e0289f8433fdccbd5b29 106 Gene3D G3DSA:2.20.25.200 59 106 9.1E-15 T 23-10-2018 Mlab_0087 00b23a16c1bf65778403f6108c9e41df 231 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.456 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 Mlab_0087 00b23a16c1bf65778403f6108c9e41df 231 SUPERFAMILY SSF54821 87 185 2.49E-27 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0087 00b23a16c1bf65778403f6108c9e41df 231 Gene3D G3DSA:3.30.1140.32 87 225 8.9E-41 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0087 00b23a16c1bf65778403f6108c9e41df 231 Gene3D G3DSA:3.30.300.20 1 86 1.6E-26 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta Mlab_0087 00b23a16c1bf65778403f6108c9e41df 231 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 196 1.9E-82 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0087 00b23a16c1bf65778403f6108c9e41df 231 SMART SM00322 38 104 2.5E-6 T 23-10-2018 IPR004087 K Homology domain GO:0003676 Mlab_0087 00b23a16c1bf65778403f6108c9e41df 231 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 2.2E-22 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0087 00b23a16c1bf65778403f6108c9e41df 231 SUPERFAMILY SSF54814 6 95 6.87E-23 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Mlab_0087 00b23a16c1bf65778403f6108c9e41df 231 Pfam PF07650 KH domain 17 85 8.9E-13 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0049 bf8d1e0d1cc081a7e2955214a50ac91c 374 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 258 353 1.1E-24 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II Mlab_0049 bf8d1e0d1cc081a7e2955214a50ac91c 374 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 235 2.9E-66 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Mlab_0049 bf8d1e0d1cc081a7e2955214a50ac91c 374 SUPERFAMILY SSF52518 4 247 6.42E-67 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_0049 bf8d1e0d1cc081a7e2955214a50ac91c 374 Gene3D G3DSA:3.40.50.920 249 371 2.3E-25 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Mlab_0049 bf8d1e0d1cc081a7e2955214a50ac91c 374 Gene3D G3DSA:3.40.50.970 1 248 2.2E-96 T 23-10-2018 Mlab_0049 bf8d1e0d1cc081a7e2955214a50ac91c 374 SUPERFAMILY SSF52922 249 359 3.27E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Mlab_1560 773d683b2587280569888e0c0744c714 295 PIRSF PIRSF016509 1 295 9.1E-115 T 23-10-2018 IPR005780 Tetrahydromethanopterin S-methyltransferase, subunit E GO:0005737|GO:0006814|GO:0012506|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1560 773d683b2587280569888e0c0744c714 295 Pfam PF04206 Tetrahydromethanopterin S-methyltransferase, subunit E 8 276 1.2E-128 T 23-10-2018 IPR005780 Tetrahydromethanopterin S-methyltransferase, subunit E GO:0005737|GO:0006814|GO:0012506|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1560 773d683b2587280569888e0c0744c714 295 Hamap MF_01098 Tetrahydromethanopterin S-methyltransferase subunit E [mtrE]. 1 295 172.843 T 23-10-2018 IPR005780 Tetrahydromethanopterin S-methyltransferase, subunit E GO:0005737|GO:0006814|GO:0012506|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1560 773d683b2587280569888e0c0744c714 295 TIGRFAM TIGR01113 mtrE: tetrahydromethanopterin S-methyltransferase, subunit E 8 291 3.0E-111 T 23-10-2018 IPR005780 Tetrahydromethanopterin S-methyltransferase, subunit E GO:0005737|GO:0006814|GO:0012506|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_0510 850bef399fba06a5fef79aed5ebf3b87 451 SUPERFAMILY SSF49299 311 390 9.55E-21 T 23-10-2018 IPR035986 PKD domain superfamily Mlab_0510 850bef399fba06a5fef79aed5ebf3b87 451 Pfam PF00801 PKD domain 236 296 1.5E-5 T 23-10-2018 IPR000601 PKD domain Mlab_0510 850bef399fba06a5fef79aed5ebf3b87 451 Pfam PF00801 PKD domain 315 377 5.5E-9 T 23-10-2018 IPR000601 PKD domain Mlab_0510 850bef399fba06a5fef79aed5ebf3b87 451 Gene3D G3DSA:2.60.40.10 310 394 5.2E-20 T 23-10-2018 IPR013783 Immunoglobulin-like fold Mlab_0510 850bef399fba06a5fef79aed5ebf3b87 451 Gene3D G3DSA:2.60.40.10 223 309 4.9E-17 T 23-10-2018 IPR013783 Immunoglobulin-like fold Mlab_0510 850bef399fba06a5fef79aed5ebf3b87 451 SMART SM00089 227 306 1.0E-9 T 23-10-2018 IPR022409 PKD/Chitinase domain Mlab_0510 850bef399fba06a5fef79aed5ebf3b87 451 SMART SM00089 311 390 5.9E-18 T 23-10-2018 IPR022409 PKD/Chitinase domain Mlab_0510 850bef399fba06a5fef79aed5ebf3b87 451 SUPERFAMILY SSF49299 230 305 3.14E-14 T 23-10-2018 IPR035986 PKD domain superfamily Mlab_0518 33025f17e3c0b4e0b6728a8b25a9b950 143 Pfam PF01903 CbiX 17 129 1.9E-23 T 23-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 Mlab_0518 33025f17e3c0b4e0b6728a8b25a9b950 143 SUPERFAMILY SSF53800 10 136 6.28E-28 T 23-10-2018 Mlab_0518 33025f17e3c0b4e0b6728a8b25a9b950 143 Gene3D G3DSA:3.40.50.1400 9 139 1.4E-26 T 23-10-2018 Mlab_0641 90165f517482294b8d7cd0a22492b2e1 340 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 154 298 2.3E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Mlab_0641 90165f517482294b8d7cd0a22492b2e1 340 SUPERFAMILY SSF52540 147 313 1.09E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0641 90165f517482294b8d7cd0a22492b2e1 340 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 223 278 6.8E-21 T 23-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 Mlab_0641 90165f517482294b8d7cd0a22492b2e1 340 Gene3D G3DSA:1.20.120.1190 1 147 2.8E-39 T 23-10-2018 Mlab_0641 90165f517482294b8d7cd0a22492b2e1 340 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 157 177 1.7E-10 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0641 90165f517482294b8d7cd0a22492b2e1 340 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 196 1.7E-10 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0641 90165f517482294b8d7cd0a22492b2e1 340 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 206 221 1.7E-10 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0641 90165f517482294b8d7cd0a22492b2e1 340 Gene3D G3DSA:3.40.50.300 148 323 3.5E-42 T 23-10-2018 Mlab_0537 a763159ef49216ef775d97e310a2c5b8 526 Gene3D G3DSA:3.30.930.10 43 347 8.6E-71 T 23-10-2018 Mlab_0537 a763159ef49216ef775d97e310a2c5b8 526 TIGRFAM TIGR00470 sepS: O-phosphoserine--tRNA ligase 1 525 2.8E-203 T 23-10-2018 IPR005246 O-phosphoseryl-tRNA(Cys) ligase GO:0004812|GO:0005524|GO:0043039 KEGG: 00970+6.1.1.27|MetaCyc: PWY-6308 Mlab_0537 a763159ef49216ef775d97e310a2c5b8 526 Pfam PF01409 tRNA synthetases class II core domain (F) 125 341 8.4E-50 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 Mlab_0537 a763159ef49216ef775d97e310a2c5b8 526 Hamap MF_01674 O-phosphoserine--tRNA(Cys) ligase [sepS]. 1 526 297.828 T 23-10-2018 IPR005246 O-phosphoseryl-tRNA(Cys) ligase GO:0004812|GO:0005524|GO:0043039 KEGG: 00970+6.1.1.27|MetaCyc: PWY-6308 Mlab_0537 a763159ef49216ef775d97e310a2c5b8 526 SUPERFAMILY SSF55681 35 342 1.76E-36 T 23-10-2018 Mlab_1735 4bf91f0969f6080ff33c654de4950fae 303 SUPERFAMILY SSF56112 11 249 1.92E-33 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily Mlab_1735 4bf91f0969f6080ff33c654de4950fae 303 Pfam PF01636 Phosphotransferase enzyme family 12 234 8.2E-27 T 23-10-2018 IPR002575 Aminoglycoside phosphotransferase Mlab_1735 4bf91f0969f6080ff33c654de4950fae 303 Gene3D G3DSA:3.90.1200.10 93 281 3.7E-18 T 23-10-2018 Mlab_0254 ae1918e852b8c25618be431c82c24563 313 SMART SM00327 86 278 6.7E-21 T 23-10-2018 IPR002035 von Willebrand factor, type A Mlab_0254 ae1918e852b8c25618be431c82c24563 313 Pfam PF07584 Aerotolerance regulator N-terminal 1 76 1.2E-10 T 23-10-2018 IPR024163 Aerotolerance regulator, N-terminal Mlab_0254 ae1918e852b8c25618be431c82c24563 313 Gene3D G3DSA:3.40.50.410 83 277 2.4E-43 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Mlab_0254 ae1918e852b8c25618be431c82c24563 313 Pfam PF00092 von Willebrand factor type A domain 88 271 6.3E-22 T 23-10-2018 IPR002035 von Willebrand factor, type A Mlab_0254 ae1918e852b8c25618be431c82c24563 313 SUPERFAMILY SSF53300 85 275 1.48E-32 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Mlab_0385 73784fca407fbba1f9a7ff206fab2171 624 Pfam PF07670 Nucleoside recognition 335 426 5.3E-11 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Mlab_0385 73784fca407fbba1f9a7ff206fab2171 624 Pfam PF07670 Nucleoside recognition 491 595 4.1E-12 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Mlab_0385 73784fca407fbba1f9a7ff206fab2171 624 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 158 2.7E-12 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Mlab_0385 73784fca407fbba1f9a7ff206fab2171 624 Pfam PF07664 Ferrous iron transport protein B C terminus 434 485 9.0E-10 T 23-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 Mlab_0385 73784fca407fbba1f9a7ff206fab2171 624 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 593 3.6E-128 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 Mlab_0385 73784fca407fbba1f9a7ff206fab2171 624 Gene3D G3DSA:3.40.50.300 2 164 1.8E-40 T 23-10-2018 Mlab_0385 73784fca407fbba1f9a7ff206fab2171 624 SUPERFAMILY SSF52540 5 185 2.81E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0385 73784fca407fbba1f9a7ff206fab2171 624 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 53 68 2.1E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0385 73784fca407fbba1f9a7ff206fab2171 624 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.1E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0385 73784fca407fbba1f9a7ff206fab2171 624 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.1E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0385 73784fca407fbba1f9a7ff206fab2171 624 Pfam PF02421 Ferrous iron transport protein B 5 156 2.0E-53 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 Mlab_0638 9b23d9e1b2bab87f45d25eca4b6bb4f8 226 Hamap MF_01419 Phosphoglycolate phosphatase. 2 226 27.194 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 Mlab_0638 9b23d9e1b2bab87f45d25eca4b6bb4f8 226 Gene3D G3DSA:3.90.1070.10 86 148 8.4E-59 T 23-10-2018 Mlab_0638 9b23d9e1b2bab87f45d25eca4b6bb4f8 226 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 110 5.7E-12 T 23-10-2018 Mlab_0638 9b23d9e1b2bab87f45d25eca4b6bb4f8 226 Pfam PF08282 haloacid dehalogenase-like hydrolase 129 222 4.2E-17 T 23-10-2018 Mlab_0638 9b23d9e1b2bab87f45d25eca4b6bb4f8 226 Gene3D G3DSA:3.40.50.1000 5 215 8.4E-59 T 23-10-2018 IPR023214 HAD superfamily Mlab_0638 9b23d9e1b2bab87f45d25eca4b6bb4f8 226 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 5 222 2.5E-51 T 23-10-2018 Mlab_0638 9b23d9e1b2bab87f45d25eca4b6bb4f8 226 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 6 221 1.4E-39 T 23-10-2018 Mlab_0638 9b23d9e1b2bab87f45d25eca4b6bb4f8 226 SUPERFAMILY SSF56784 1 226 1.08E-42 T 23-10-2018 IPR036412 HAD-like superfamily Mlab_0638 9b23d9e1b2bab87f45d25eca4b6bb4f8 226 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 194 3.6E-15 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 Mlab_1720 4a842958702f63baa4d41b9b366fc637 350 Gene3D G3DSA:1.10.3470.10 14 349 5.7E-98 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_1720 4a842958702f63baa4d41b9b366fc637 350 Pfam PF01032 FecCD transport family 32 344 3.9E-84 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Mlab_1720 4a842958702f63baa4d41b9b366fc637 350 SUPERFAMILY SSF81345 17 344 7.06E-75 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_1083 1b88003b751ca53e141ea0df163f1b77 192 Gene3D G3DSA:3.30.950.10 92 186 2.0E-8 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Mlab_1083 1b88003b751ca53e141ea0df163f1b77 192 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 173 4.8E-20 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Mlab_1083 1b88003b751ca53e141ea0df163f1b77 192 SUPERFAMILY SSF53790 3 177 2.49E-28 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Mlab_1083 1b88003b751ca53e141ea0df163f1b77 192 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 3 178 3.7E-32 T 23-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 Mlab_1083 1b88003b751ca53e141ea0df163f1b77 192 Gene3D G3DSA:3.40.1010.10 1 91 1.3E-11 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Mlab_0986 53416e6c89a21a93a7f45c82b999ed74 219 SUPERFAMILY SSF102198 1 215 1.01E-51 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Mlab_0986 53416e6c89a21a93a7f45c82b999ed74 219 Pfam PF04199 Putative cyclase 4 152 3.9E-30 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Mlab_0986 53416e6c89a21a93a7f45c82b999ed74 219 Gene3D G3DSA:3.50.30.50 1 219 1.5E-58 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Mlab_0823 d8ed4bdf6e22233f14b9c411e2f9f1a2 85 SUPERFAMILY SSF69025 3 85 1.09E-27 T 23-10-2018 IPR036825 MTH865-like superfamily Mlab_0823 d8ed4bdf6e22233f14b9c411e2f9f1a2 85 Gene3D G3DSA:1.10.238.80 3 85 2.7E-30 T 23-10-2018 IPR036825 MTH865-like superfamily Mlab_0823 d8ed4bdf6e22233f14b9c411e2f9f1a2 85 Pfam PF07747 MTH865-like family 12 81 1.4E-27 T 23-10-2018 IPR024093 Uncharacterised protein family MTH865 Mlab_0669 a20118e699c008dd88bf2b81d96593f0 176 SUPERFAMILY SSF102198 2 173 1.44E-43 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Mlab_0669 a20118e699c008dd88bf2b81d96593f0 176 Gene3D G3DSA:3.50.30.50 1 85 4.1E-21 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Mlab_0669 a20118e699c008dd88bf2b81d96593f0 176 Pfam PF04199 Putative cyclase 5 79 1.9E-9 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Mlab_0669 a20118e699c008dd88bf2b81d96593f0 176 Gene3D G3DSA:3.50.30.50 86 174 1.1E-21 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Mlab_1010 f7abca260e56d09fc52f498baa86b03b 101 SUPERFAMILY SSF47240 14 87 1.34E-16 T 23-10-2018 IPR009078 Ferritin-like superfamily Mlab_1010 f7abca260e56d09fc52f498baa86b03b 101 Pfam PF02915 Rubrerythrin 30 94 1.5E-7 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 Mlab_1010 f7abca260e56d09fc52f498baa86b03b 101 Gene3D G3DSA:1.20.1260.10 5 82 2.5E-8 T 23-10-2018 IPR012347 Ferritin-like Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 SUPERFAMILY SSF81653 128 225 5.62E-22 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 463 473 2.4E-22 T 23-10-2018 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 543 555 2.4E-22 T 23-10-2018 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 175 189 2.4E-22 T 23-10-2018 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 519 538 2.4E-22 T 23-10-2018 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 326 340 2.4E-22 T 23-10-2018 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 328 334 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 Gene3D G3DSA:2.70.150.20 118 230 4.3E-28 T 23-10-2018 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 Gene3D G3DSA:3.40.1110.10 337 447 1.4E-82 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 96 601 1.6E-72 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 SUPERFAMILY SSF81665 76 619 5.75E-14 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 76 624 2.7E-152 T 23-10-2018 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 Gene3D G3DSA:3.40.50.1000 307 572 1.4E-82 T 23-10-2018 IPR023214 HAD superfamily Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 Pfam PF00122 E1-E2 ATPase 126 305 2.3E-45 T 23-10-2018 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 77 621 2.2E-165 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 SUPERFAMILY SSF56784 324 620 1.15E-62 T 23-10-2018 IPR036412 HAD-like superfamily Mlab_1065 d6fb1dbc59a7f06633edcd9e9aad1376 626 Pfam PF00702 haloacid dehalogenase-like hydrolase 323 533 9.8E-37 T 23-10-2018 Mlab_1058 fa9a80dc17379983db039dee24596702 412 Pfam PF13534 4Fe-4S dicluster domain 291 355 3.7E-5 T 23-10-2018 Mlab_1058 fa9a80dc17379983db039dee24596702 412 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 93 247 3.3E-35 T 23-10-2018 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal Mlab_1058 fa9a80dc17379983db039dee24596702 412 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 341 352 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_1058 fa9a80dc17379983db039dee24596702 412 SUPERFAMILY SSF46548 278 357 1.8E-12 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Mlab_1058 fa9a80dc17379983db039dee24596702 412 Gene3D G3DSA:3.30.70.3270 267 399 1.3E-7 T 23-10-2018 Mlab_1058 fa9a80dc17379983db039dee24596702 412 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 7 83 2.1E-19 T 23-10-2018 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal Mlab_0553 4cdaf3a611aea46b2a953a2e6bffb515 153 TIGRFAM TIGR03272 methan_mark_6: putative methanogenesis marker protein 6 15 147 2.4E-40 T 23-10-2018 IPR012025 Uncharacterised conserved protein UCP005642, methanogenesis Mlab_0553 4cdaf3a611aea46b2a953a2e6bffb515 153 Pfam PF09875 Uncharacterized protein conserved in archaea (DUF2102) 15 116 2.9E-40 T 23-10-2018 IPR012025 Uncharacterised conserved protein UCP005642, methanogenesis Mlab_0761 80f3b2d2e21403f60963d3bf930f54a8 710 Gene3D G3DSA:3.40.50.300 11 210 3.4E-41 T 23-10-2018 Mlab_0761 80f3b2d2e21403f60963d3bf930f54a8 710 Pfam PF00270 DEAD/DEAH box helicase 27 193 2.1E-25 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Mlab_0761 80f3b2d2e21403f60963d3bf930f54a8 710 Gene3D G3DSA:3.40.50.300 231 380 1.1E-25 T 23-10-2018 Mlab_0761 80f3b2d2e21403f60963d3bf930f54a8 710 SUPERFAMILY SSF52540 37 350 3.68E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0761 80f3b2d2e21403f60963d3bf930f54a8 710 SMART SM00487 20 223 4.2E-28 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Mlab_0761 80f3b2d2e21403f60963d3bf930f54a8 710 Pfam PF00271 Helicase conserved C-terminal domain 242 339 1.8E-15 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0761 80f3b2d2e21403f60963d3bf930f54a8 710 SMART SM00490 258 339 3.3E-19 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0214 75400a7442446884a1232d2b0e7da929 435 Gene3D G3DSA:2.60.40.1120 184 249 7.2E-8 T 23-10-2018 Mlab_0214 75400a7442446884a1232d2b0e7da929 435 Pfam PF08308 PEGA domain 336 403 9.0E-17 T 23-10-2018 IPR013229 PEGA Mlab_0214 75400a7442446884a1232d2b0e7da929 435 Pfam PF08308 PEGA domain 111 176 7.3E-18 T 23-10-2018 IPR013229 PEGA Mlab_0214 75400a7442446884a1232d2b0e7da929 435 Pfam PF08308 PEGA domain 182 248 1.2E-18 T 23-10-2018 IPR013229 PEGA Mlab_0214 75400a7442446884a1232d2b0e7da929 435 Pfam PF08308 PEGA domain 253 328 1.9E-5 T 23-10-2018 IPR013229 PEGA Mlab_0214 75400a7442446884a1232d2b0e7da929 435 SUPERFAMILY SSF49452 202 246 4.51E-6 T 23-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 Mlab_1314 2941cb5f54fb69d0065ca3e7c64d640c 93 Pfam PF13616 PPIC-type PPIASE domain 3 91 1.2E-28 T 23-10-2018 Mlab_1314 2941cb5f54fb69d0065ca3e7c64d640c 93 SUPERFAMILY SSF54534 4 92 9.81E-34 T 23-10-2018 Mlab_1314 2941cb5f54fb69d0065ca3e7c64d640c 93 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 30 50 - T 23-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 Mlab_1314 2941cb5f54fb69d0065ca3e7c64d640c 93 Gene3D G3DSA:3.10.50.40 2 91 2.6E-40 T 23-10-2018 Mlab_1030 dd743b56c42bb5229106d8fae7ad7523 454 SUPERFAMILY SSF51998 2 449 5.04E-179 T 23-10-2018 Mlab_1030 dd743b56c42bb5229106d8fae7ad7523 454 Pfam PF05167 Uncharacterised ACR (DUF711) 13 418 1.3E-182 T 23-10-2018 IPR007841 Uncharacterised protein family UPF0210 Mlab_1030 dd743b56c42bb5229106d8fae7ad7523 454 Hamap MF_01221 UPF0210 protein . 2 454 51.844 T 23-10-2018 IPR007841 Uncharacterised protein family UPF0210 Mlab_1030 dd743b56c42bb5229106d8fae7ad7523 454 Gene3D G3DSA:3.20.70.20 1 454 3.6E-184 T 23-10-2018 Mlab_1662 322ec483154ec3047050b22fd59b8d4d 165 SUPERFAMILY SSF55729 1 161 2.7E-29 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_1662 322ec483154ec3047050b22fd59b8d4d 165 Pfam PF13420 Acetyltransferase (GNAT) domain 7 156 2.9E-14 T 23-10-2018 Mlab_1662 322ec483154ec3047050b22fd59b8d4d 165 Gene3D G3DSA:3.40.630.30 1 163 7.8E-37 T 23-10-2018 Mlab_0734 8ee174068eb755c75498fec95c04beda 402 Gene3D G3DSA:1.20.58.220 204 313 4.0E-18 T 23-10-2018 IPR038078 PhoU-like domain superfamily Mlab_0734 8ee174068eb755c75498fec95c04beda 402 Gene3D G3DSA:1.20.58.220 2 112 2.0E-18 T 23-10-2018 IPR038078 PhoU-like domain superfamily Mlab_0734 8ee174068eb755c75498fec95c04beda 402 SUPERFAMILY SSF116726 109 190 1.96E-13 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Mlab_0734 8ee174068eb755c75498fec95c04beda 402 SUPERFAMILY SSF116726 305 390 7.32E-16 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Mlab_0734 8ee174068eb755c75498fec95c04beda 402 Pfam PF01895 PhoU domain 215 297 1.0E-10 T 23-10-2018 IPR026022 PhoU domain Mlab_0734 8ee174068eb755c75498fec95c04beda 402 Pfam PF01895 PhoU domain 14 97 2.8E-10 T 23-10-2018 IPR026022 PhoU domain Mlab_0734 8ee174068eb755c75498fec95c04beda 402 Pfam PF02080 TrkA-C domain 123 174 9.7E-11 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Mlab_0734 8ee174068eb755c75498fec95c04beda 402 Pfam PF02080 TrkA-C domain 320 387 4.1E-7 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Mlab_0734 8ee174068eb755c75498fec95c04beda 402 SUPERFAMILY SSF109755 6 101 3.27E-15 T 23-10-2018 Mlab_0734 8ee174068eb755c75498fec95c04beda 402 SUPERFAMILY SSF109755 205 300 2.09E-14 T 23-10-2018 Mlab_0734 8ee174068eb755c75498fec95c04beda 402 Gene3D G3DSA:3.30.70.1450 114 193 7.0E-14 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Mlab_0734 8ee174068eb755c75498fec95c04beda 402 Gene3D G3DSA:3.30.70.1450 314 397 6.5E-13 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Mlab_1123 0ef026bc0cb5285905b059a2467e2cac 243 Gene3D G3DSA:3.30.70.2970 45 155 1.0E-47 T 23-10-2018 Mlab_1123 0ef026bc0cb5285905b059a2467e2cac 243 Gene3D G3DSA:3.30.110.170 35 241 1.0E-47 T 23-10-2018 Mlab_1123 0ef026bc0cb5285905b059a2467e2cac 243 Pfam PF04402 Protein of unknown function (DUF541) 33 241 1.3E-39 T 23-10-2018 IPR007497 Protein of unknown function DUF541 Mlab_0595 789d8f65c6a52f87a723b539c4c2fdc3 208 Pfam PF14353 CpXC protein 8 126 3.1E-33 T 23-10-2018 IPR025682 CpXC domain Mlab_0340 dfd58f42f2d65675695bf8cbcaadf3fd 268 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 82 93 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0340 dfd58f42f2d65675695bf8cbcaadf3fd 268 Gene3D G3DSA:3.30.70.20 49 95 2.0E-8 T 23-10-2018 Mlab_0340 dfd58f42f2d65675695bf8cbcaadf3fd 268 SUPERFAMILY SSF54862 39 101 1.05E-15 T 23-10-2018 Mlab_0340 dfd58f42f2d65675695bf8cbcaadf3fd 268 SUPERFAMILY SSF52540 2 249 2.5E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0340 dfd58f42f2d65675695bf8cbcaadf3fd 268 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 2 240 3.5E-10 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Mlab_0120 15cae823f3c03e5478d046d54e4bf8d6 200 Pfam PF03358 NADPH-dependent FMN reductase 4 104 1.4E-20 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Mlab_0120 15cae823f3c03e5478d046d54e4bf8d6 200 SUPERFAMILY SSF52218 1 193 4.66E-32 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0120 15cae823f3c03e5478d046d54e4bf8d6 200 Gene3D G3DSA:3.40.50.360 2 191 5.8E-36 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0946 1bfd028eb7dc7b1bb9d145b4b4ea8520 209 Pfam PF13197 Protein of unknown function (DUF4013) 29 181 1.9E-23 T 23-10-2018 IPR025098 Protein of unknown function DUF4013 Mlab_0215 e04957ae03c5b0bcfb1b5ef4870d25d6 300 Pfam PF01913 Formylmethanofuran-tetrahydromethanopterin formyltransferase 7 147 2.8E-57 T 23-10-2018 IPR022667 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal GO:0006730|GO:0016740 Mlab_0215 e04957ae03c5b0bcfb1b5ef4870d25d6 300 SUPERFAMILY SSF55112 150 299 4.71E-64 T 23-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily Mlab_0215 e04957ae03c5b0bcfb1b5ef4870d25d6 300 SUPERFAMILY SSF55112 7 148 2.88E-54 T 23-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily Mlab_0215 e04957ae03c5b0bcfb1b5ef4870d25d6 300 Gene3D G3DSA:3.30.70.520 10 298 5.7E-127 T 23-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily Mlab_0215 e04957ae03c5b0bcfb1b5ef4870d25d6 300 Hamap MF_00579 Formylmethanofuran--tetrahydromethanopterin formyltransferase [ftr]. 7 300 45.632 T 23-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 Mlab_0215 e04957ae03c5b0bcfb1b5ef4870d25d6 300 PIRSF PIRSF006414 7 300 5.4E-128 T 23-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 Mlab_0215 e04957ae03c5b0bcfb1b5ef4870d25d6 300 Gene3D G3DSA:3.30.70.520 23 165 5.7E-127 T 23-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily Mlab_0215 e04957ae03c5b0bcfb1b5ef4870d25d6 300 Pfam PF02741 FTR, proximal lobe 150 298 1.6E-69 T 23-10-2018 IPR002770 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal GO:0006730|GO:0016740 Mlab_0215 e04957ae03c5b0bcfb1b5ef4870d25d6 300 TIGRFAM TIGR03119 one_C_fhcD: formylmethanofuran--tetrahydromethanopterin N-formyltransferase 15 298 3.3E-126 T 23-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 Mlab_0266 89c6282efe6aef7b5b1db289406fb0d6 393 PIRSF PIRSF005572 3 382 1.6E-133 T 23-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Mlab_0266 89c6282efe6aef7b5b1db289406fb0d6 393 SUPERFAMILY SSF53383 4 376 1.45E-111 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_0266 89c6282efe6aef7b5b1db289406fb0d6 393 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 2 393 51.849 T 23-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 Mlab_0266 89c6282efe6aef7b5b1db289406fb0d6 393 Gene3D G3DSA:3.90.1150.10 6 374 6.3E-157 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_0266 89c6282efe6aef7b5b1db289406fb0d6 393 Pfam PF00266 Aminotransferase class-V 6 366 2.2E-82 T 23-10-2018 IPR000192 Aminotransferase class V domain Mlab_0266 89c6282efe6aef7b5b1db289406fb0d6 393 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 195 214 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Mlab_0266 89c6282efe6aef7b5b1db289406fb0d6 393 Gene3D G3DSA:3.40.640.10 17 258 6.3E-157 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_0266 89c6282efe6aef7b5b1db289406fb0d6 393 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 6 384 3.2E-182 T 23-10-2018 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Mlab_0806 9e684b040fae83259b2dd7a892f95fee 334 Gene3D G3DSA:3.40.50.720 25 319 1.2E-81 T 23-10-2018 Mlab_0806 9e684b040fae83259b2dd7a892f95fee 334 SUPERFAMILY SSF51735 115 302 1.54E-42 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0806 9e684b040fae83259b2dd7a892f95fee 334 SUPERFAMILY SSF52283 13 135 5.95E-23 T 23-10-2018 Mlab_0806 9e684b040fae83259b2dd7a892f95fee 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 121 302 2.3E-46 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Mlab_0806 9e684b040fae83259b2dd7a892f95fee 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 156 184 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Mlab_0806 9e684b040fae83259b2dd7a892f95fee 334 Gene3D G3DSA:3.40.50.720 108 304 1.2E-81 T 23-10-2018 Mlab_0806 9e684b040fae83259b2dd7a892f95fee 334 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 205 227 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Mlab_0806 9e684b040fae83259b2dd7a892f95fee 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 333 1.2E-20 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 Mlab_1059 b78e150f19bdbcd62cf757a50e12a56c 317 SUPERFAMILY SSF103481 205 309 4.71E-16 T 23-10-2018 Mlab_1059 b78e150f19bdbcd62cf757a50e12a56c 317 SUPERFAMILY SSF103481 58 156 1.44E-15 T 23-10-2018 Mlab_1059 b78e150f19bdbcd62cf757a50e12a56c 317 Pfam PF00892 EamA-like transporter family 170 305 2.4E-26 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Mlab_1059 b78e150f19bdbcd62cf757a50e12a56c 317 Pfam PF00892 EamA-like transporter family 24 156 3.0E-22 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Mlab_1059 b78e150f19bdbcd62cf757a50e12a56c 317 Gene3D G3DSA:1.10.3730.20 201 312 6.9E-6 T 23-10-2018 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 Gene3D G3DSA:3.40.50.740 66 531 5.0E-186 T 23-10-2018 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 Pfam PF01568 Molydopterin dinucleotide binding domain 574 680 9.9E-32 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 SMART SM00926 4 58 6.0E-20 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 9 683 1.2E-262 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 58 3.2E-18 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 SUPERFAMILY SSF50692 536 685 3.11E-52 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 Gene3D G3DSA:2.20.25.90 4 58 9.5E-20 T 23-10-2018 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 Gene3D G3DSA:3.40.228.10 135 335 5.0E-186 T 23-10-2018 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 SUPERFAMILY SSF53706 3 576 1.01E-201 T 23-10-2018 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 432 449 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 Pfam PF00384 Molybdopterin oxidoreductase 61 486 6.1E-85 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 Gene3D G3DSA:2.40.40.20 564 686 1.4E-47 T 23-10-2018 Mlab_0463 13eed468e397d00420ea2ef7de5a51f5 689 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 9 26 - T 23-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 Mlab_1472 60d2bfcb6fa15817809ca9a40dd24495 299 SMART SM00478 128 292 2.8E-5 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Mlab_1472 60d2bfcb6fa15817809ca9a40dd24495 299 SUPERFAMILY SSF55945 22 117 5.02E-18 T 23-10-2018 Mlab_1472 60d2bfcb6fa15817809ca9a40dd24495 299 Gene3D G3DSA:1.10.1670.50 239 299 5.0E-20 T 23-10-2018 Mlab_1472 60d2bfcb6fa15817809ca9a40dd24495 299 Pfam PF07934 8-oxoguanine DNA glycosylase, N-terminal domain 26 123 3.6E-17 T 23-10-2018 IPR012904 8-oxoguanine DNA glycosylase, N-terminal GO:0003684|GO:0006289|GO:0008534 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357|Reactome: R-HSA-5649702 Mlab_1472 60d2bfcb6fa15817809ca9a40dd24495 299 Gene3D G3DSA:3.30.310.260 8 117 8.4E-16 T 23-10-2018 Mlab_1472 60d2bfcb6fa15817809ca9a40dd24495 299 Gene3D G3DSA:1.10.340.30 118 238 3.9E-38 T 23-10-2018 Mlab_1472 60d2bfcb6fa15817809ca9a40dd24495 299 SUPERFAMILY SSF48150 118 288 3.77E-34 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Mlab_0923 f12ab14892dc3748b8730291e44051f5 289 Pfam PF02475 Met-10+ like-protein 58 243 2.6E-38 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 Mlab_0923 f12ab14892dc3748b8730291e44051f5 289 SUPERFAMILY SSF53335 77 288 1.13E-47 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0923 f12ab14892dc3748b8730291e44051f5 289 Gene3D G3DSA:3.40.50.150 57 288 1.7E-53 T 23-10-2018 Mlab_0998 f7b0357e883021fb9eb30931e1431b31 399 Pfam PF01384 Phosphate transporter family 176 386 4.8E-48 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 Mlab_0998 f7b0357e883021fb9eb30931e1431b31 399 Pfam PF01384 Phosphate transporter family 23 180 2.6E-32 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 Mlab_0317 a7d86e76fa2d7fb0889ece99145c0033 169 SUPERFAMILY SSF53271 4 166 4.46E-38 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like Mlab_0317 a7d86e76fa2d7fb0889ece99145c0033 169 Pfam PF00156 Phosphoribosyl transferase domain 43 149 3.5E-13 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Mlab_0317 a7d86e76fa2d7fb0889ece99145c0033 169 Gene3D G3DSA:3.40.50.2020 1 169 3.4E-50 T 23-10-2018 Mlab_0317 a7d86e76fa2d7fb0889ece99145c0033 169 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 169 23.764 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_0317 a7d86e76fa2d7fb0889ece99145c0033 169 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 8 166 2.6E-43 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_1259 c476b563207d3128e5f7a35de8076840 147 SUPERFAMILY SSF46785 9 141 1.39E-25 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1259 c476b563207d3128e5f7a35de8076840 147 Gene3D G3DSA:1.10.10.10 6 140 5.8E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1259 c476b563207d3128e5f7a35de8076840 147 Pfam PF12802 MarR family 33 92 1.4E-9 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_1259 c476b563207d3128e5f7a35de8076840 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 3.2E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_1259 c476b563207d3128e5f7a35de8076840 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 3.2E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_1259 c476b563207d3128e5f7a35de8076840 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 3.2E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_1259 c476b563207d3128e5f7a35de8076840 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 3.2E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_1259 c476b563207d3128e5f7a35de8076840 147 SMART SM00347 27 129 1.7E-9 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0046 65b5d0468411c9649b0742be7a8fae71 242 Gene3D G3DSA:3.40.50.300 26 102 5.1E-9 T 23-10-2018 Mlab_0046 65b5d0468411c9649b0742be7a8fae71 242 SMART SM00382 39 210 1.9E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0046 65b5d0468411c9649b0742be7a8fae71 242 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 150 196 4.9E-8 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_0046 65b5d0468411c9649b0742be7a8fae71 242 SUPERFAMILY SSF52540 32 205 2.54E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0046 65b5d0468411c9649b0742be7a8fae71 242 Gene3D G3DSA:3.40.50.300 103 225 3.5E-9 T 23-10-2018 Mlab_0046 65b5d0468411c9649b0742be7a8fae71 242 Pfam PF13476 AAA domain 35 84 3.7E-9 T 23-10-2018 IPR038729 Rad50/SbcC-type AAA domain Mlab_0588 781e98ab8b87d89b3eea23b69015e78f 81 Pfam PF04024 PspC domain 6 62 4.9E-20 T 23-10-2018 IPR007168 Phage shock protein, PspC, N-terminal Mlab_1144 98d92ed7dbad79163e1cabf5c9d38835 924 SUPERFAMILY SSF55486 303 514 8.06E-41 T 23-10-2018 Mlab_1144 98d92ed7dbad79163e1cabf5c9d38835 924 Gene3D G3DSA:2.60.40.1730 15 201 2.5E-37 T 23-10-2018 Mlab_1144 98d92ed7dbad79163e1cabf5c9d38835 924 SUPERFAMILY SSF63737 13 200 7.85E-36 T 23-10-2018 Mlab_1144 98d92ed7dbad79163e1cabf5c9d38835 924 Pfam PF01433 Peptidase family M1 domain 278 504 7.9E-26 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Mlab_1144 98d92ed7dbad79163e1cabf5c9d38835 924 Gene3D G3DSA:1.25.50.10 598 910 1.4E-34 T 23-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily Mlab_1144 98d92ed7dbad79163e1cabf5c9d38835 924 Gene3D G3DSA:1.10.390.60 272 509 3.4E-32 T 23-10-2018 Mlab_1144 98d92ed7dbad79163e1cabf5c9d38835 924 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 600 908 7.5E-31 T 23-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal Mlab_0639 8d1fab488b2745b3181387b9ee4fd06e 83 SUPERFAMILY SSF50346 8 78 3.14E-11 T 23-10-2018 IPR011033 PRC-barrel-like superfamily Mlab_0639 8d1fab488b2745b3181387b9ee4fd06e 83 Pfam PF05239 PRC-barrel domain 6 78 1.0E-12 T 23-10-2018 IPR027275 PRC-barrel domain Mlab_0639 8d1fab488b2745b3181387b9ee4fd06e 83 Gene3D G3DSA:2.30.30.240 5 80 2.4E-9 T 23-10-2018 Mlab_1687 e1dd082397b8639e990bf3a603756425 172 Gene3D G3DSA:3.20.80.10 2 172 3.0E-38 T 23-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily Mlab_1687 e1dd082397b8639e990bf3a603756425 172 SUPERFAMILY SSF55136 2 170 6.02E-42 T 23-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily Mlab_1687 e1dd082397b8639e990bf3a603756425 172 Pfam PF04832 SOUL heme-binding protein 3 168 4.3E-40 T 23-10-2018 IPR006917 SOUL haem-binding protein Mlab_1491 4882fe7b09ccfb29a200abdcde4e5e62 397 Gene3D G3DSA:3.30.1330.20 228 374 6.3E-37 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 Mlab_1491 4882fe7b09ccfb29a200abdcde4e5e62 397 SMART SM00864 2 194 6.6E-11 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Mlab_1491 4882fe7b09ccfb29a200abdcde4e5e62 397 SUPERFAMILY SSF52490 1 194 7.98E-39 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Mlab_1491 4882fe7b09ccfb29a200abdcde4e5e62 397 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 395 37.12 T 23-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 Mlab_1491 4882fe7b09ccfb29a200abdcde4e5e62 397 Gene3D G3DSA:3.40.50.1440 1 227 4.5E-78 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Mlab_1491 4882fe7b09ccfb29a200abdcde4e5e62 397 PRINTS PR00423 Cell division protein FtsZ signature 99 119 6.4E-6 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Mlab_1491 4882fe7b09ccfb29a200abdcde4e5e62 397 PRINTS PR00423 Cell division protein FtsZ signature 215 236 6.4E-6 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Mlab_1491 4882fe7b09ccfb29a200abdcde4e5e62 397 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 107 113 - T 23-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 Mlab_1491 4882fe7b09ccfb29a200abdcde4e5e62 397 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 3 173 1.3E-25 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Mlab_1647 ebcbeb910f58156d207149fd41b5c270 310 Pfam PF03547 Membrane transport protein 7 154 3.4E-11 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Mlab_1647 ebcbeb910f58156d207149fd41b5c270 310 Pfam PF03547 Membrane transport protein 160 304 1.7E-19 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Mlab_0931 9e2a88691a337624bffd9491ebd3a744 119 Hamap MF_01223 UPF0212 protein . 1 111 27.746 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 Mlab_0931 9e2a88691a337624bffd9491ebd3a744 119 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 3 100 1.0E-31 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 Mlab_0931 9e2a88691a337624bffd9491ebd3a744 119 Pfam PF04475 Protein of unknown function (DUF555) 3 102 6.7E-45 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 Mlab_1709 6455536de31ead5e63b8c43f6544ce7f 688 Pfam PF03176 MMPL family 42 326 4.3E-27 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Mlab_1709 6455536de31ead5e63b8c43f6544ce7f 688 Pfam PF03176 MMPL family 460 668 5.7E-25 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Mlab_1709 6455536de31ead5e63b8c43f6544ce7f 688 Gene3D G3DSA:1.20.1640.10 497 679 8.1E-8 T 23-10-2018 Mlab_1709 6455536de31ead5e63b8c43f6544ce7f 688 SUPERFAMILY SSF82866 464 672 2.22E-22 T 23-10-2018 Mlab_1709 6455536de31ead5e63b8c43f6544ce7f 688 Gene3D G3DSA:1.20.1640.10 133 335 3.9E-10 T 23-10-2018 Mlab_1709 6455536de31ead5e63b8c43f6544ce7f 688 SUPERFAMILY SSF82866 144 326 1.7E-26 T 23-10-2018 Mlab_1515 1fa521ad171b60a170f4b1104303614a 215 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 37 195 4.6E-22 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain Mlab_1515 1fa521ad171b60a170f4b1104303614a 215 Gene3D G3DSA:3.40.50.300 14 215 9.7E-52 T 23-10-2018 Mlab_1515 1fa521ad171b60a170f4b1104303614a 215 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 2 213 4.3E-77 T 23-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 Mlab_1515 1fa521ad171b60a170f4b1104303614a 215 SUPERFAMILY SSF52540 28 214 2.31E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1515 1fa521ad171b60a170f4b1104303614a 215 PIRSF PIRSF005624 1 215 1.2E-75 T 23-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 Mlab_0579 379163f510083ad5096cf3d82e9bb9db 92 ProDom PD052873 AF2193 1 38 5.0E-11 T 23-10-2018 IPR035258 Protein of unknown function DUF5350 Mlab_0579 379163f510083ad5096cf3d82e9bb9db 92 Pfam PF17299 Family of unknown function (DUF5350) 1 56 1.6E-26 T 23-10-2018 IPR035258 Protein of unknown function DUF5350 Mlab_0146 63990e4a30e3eb4892b61490d8c0793e 183 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 9 168 1.3E-45 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 Mlab_0146 63990e4a30e3eb4892b61490d8c0793e 183 Pfam PF03367 ZPR1 zinc-finger domain 8 158 2.2E-31 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 Mlab_0146 63990e4a30e3eb4892b61490d8c0793e 183 Gene3D G3DSA:2.60.120.1040 52 175 4.6E-19 T 23-10-2018 Mlab_0146 63990e4a30e3eb4892b61490d8c0793e 183 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 8 169 3.6E-42 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 Mlab_0146 63990e4a30e3eb4892b61490d8c0793e 183 SMART SM00709 7 160 5.8E-32 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 Mlab_0647 469d079224105b0771519b12d8b66ba2 279 SUPERFAMILY SSF53335 124 233 1.9E-7 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1684 af767ce0a34e24bcb84a2692289f45a7 606 SUPERFAMILY SSF52540 298 464 1.31E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1684 af767ce0a34e24bcb84a2692289f45a7 606 SMART SM00885 122 286 1.2E-26 T 23-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal Mlab_1684 af767ce0a34e24bcb84a2692289f45a7 606 Pfam PF08706 D5 N terminal like 124 260 8.5E-5 T 23-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal Mlab_1684 af767ce0a34e24bcb84a2692289f45a7 606 Gene3D G3DSA:3.40.50.300 298 484 2.2E-5 T 23-10-2018 Mlab_0133 e14faa7f9543fd1a61840a47b1aebae5 191 SMART SM00382 20 191 1.8E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0133 e14faa7f9543fd1a61840a47b1aebae5 191 Pfam PF00005 ABC transporter 17 149 9.9E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0133 e14faa7f9543fd1a61840a47b1aebae5 191 SUPERFAMILY SSF52540 12 189 6.86E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0133 e14faa7f9543fd1a61840a47b1aebae5 191 Gene3D G3DSA:3.40.50.300 5 190 1.0E-38 T 23-10-2018 Mlab_1166 6b1d03a8c0c7532b2479093cb4889668 463 Pfam PF01554 MatE 251 409 3.9E-24 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Mlab_1166 6b1d03a8c0c7532b2479093cb4889668 463 Pfam PF01554 MatE 23 182 3.8E-37 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Mlab_1166 6b1d03a8c0c7532b2479093cb4889668 463 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 424 8.8E-67 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Mlab_1166 6b1d03a8c0c7532b2479093cb4889668 463 PIRSF PIRSF006603 1 460 2.4E-141 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Mlab_0086 0029f0c924d181b51d29d8b7938d45e3 157 ProSitePatterns PS00464 Ribosomal protein L22 signature. 129 153 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0086 0029f0c924d181b51d29d8b7938d45e3 157 Gene3D G3DSA:3.90.470.10 1 157 1.3E-45 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 Mlab_0086 0029f0c924d181b51d29d8b7938d45e3 157 Pfam PF00237 Ribosomal protein L22p/L17e 18 154 1.2E-27 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 Mlab_0086 0029f0c924d181b51d29d8b7938d45e3 157 SUPERFAMILY SSF54843 5 155 9.42E-43 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 Mlab_0086 0029f0c924d181b51d29d8b7938d45e3 157 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 2 156 32.757 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0086 0029f0c924d181b51d29d8b7938d45e3 157 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 13 155 1.1E-43 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0243 943ff8e222407857a8f6ed6767f16e31 131 Gene3D G3DSA:2.40.40.20 4 131 7.5E-44 T 23-10-2018 Mlab_0243 943ff8e222407857a8f6ed6767f16e31 131 Pfam PF01568 Molydopterin dinucleotide binding domain 6 106 4.7E-15 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Mlab_0243 943ff8e222407857a8f6ed6767f16e31 131 SUPERFAMILY SSF50692 5 117 2.26E-22 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Mlab_0243 943ff8e222407857a8f6ed6767f16e31 131 PIRSF PIRSF015873 4 131 4.5E-42 T 23-10-2018 IPR012040 Formylmethanofuran dehydrogenase, subunit D Mlab_1681 0b11cf55ad7513c4ff308c15b6ea01fc 366 SUPERFAMILY SSF53335 20 320 2.78E-16 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1681 0b11cf55ad7513c4ff308c15b6ea01fc 366 Gene3D G3DSA:3.40.50.150 2 118 6.7E-8 T 23-10-2018 Mlab_1681 0b11cf55ad7513c4ff308c15b6ea01fc 366 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 50 61 - T 23-10-2018 IPR000241 Putative RNA methylase domain Mlab_1681 0b11cf55ad7513c4ff308c15b6ea01fc 366 Gene3D G3DSA:3.40.50.150 221 359 1.2E-5 T 23-10-2018 Mlab_1681 0b11cf55ad7513c4ff308c15b6ea01fc 366 Pfam PF01170 Putative RNA methylase family UPF0020 42 70 1.6E-5 T 23-10-2018 IPR000241 Putative RNA methylase domain Mlab_1621 46aa78fa40ae744a1db12143d3f55530 127 SUPERFAMILY SSF143243 5 121 1.57E-14 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_1621 46aa78fa40ae744a1db12143d3f55530 127 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 9 93 1.9E-7 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0126 0bc48e31624d94d7deed40c03cacf60f 104 ProDom PD066267 AF1218 MA3722 MA2389 18 101 3.0E-9 T 23-10-2018 IPR020501 Uncharacterised protein family AF1218 Mlab_0126 0bc48e31624d94d7deed40c03cacf60f 104 Pfam PF10826 Protein of unknown function (DUF2551) 15 97 3.5E-33 T 23-10-2018 IPR020501 Uncharacterised protein family AF1218 Mlab_0955 fc972eef3a2f95d2917711a069be3103 523 Pfam PF00361 Proton-conducting membrane transporter 143 445 3.6E-47 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0955 fc972eef3a2f95d2917711a069be3103 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 179 203 1.8E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0955 fc972eef3a2f95d2917711a069be3103 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 402 428 1.8E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0955 fc972eef3a2f95d2917711a069be3103 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 350 369 1.8E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 PIRSF PIRSF000854 506 751 9.7E-49 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 PIRSF PIRSF000854 1 506 8.3E-137 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 Gene3D G3DSA:3.30.470.20 188 334 2.1E-43 T 23-10-2018 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 Pfam PF00391 PEP-utilising enzyme, mobile domain 363 434 8.5E-27 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 SUPERFAMILY SSF52009 331 441 1.57E-34 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 325 9.5E-108 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 SUPERFAMILY SSF51621 463 746 1.1E-85 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 SUPERFAMILY SSF56059 3 363 4.0E-99 T 23-10-2018 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 669 684 1.2E-12 T 23-10-2018 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 705 717 1.2E-12 T 23-10-2018 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 489 508 1.2E-12 T 23-10-2018 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 652 667 1.2E-12 T 23-10-2018 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 Gene3D G3DSA:3.20.20.60 453 758 1.5E-91 T 23-10-2018 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 393 404 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 747 7.2E-266 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 463 746 3.8E-79 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 Gene3D G3DSA:3.30.1490.20 3 186 9.1E-70 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Mlab_1544 57ece6d712893ce461fd01dda8406eb4 758 Gene3D G3DSA:3.50.30.10 335 444 4.2E-40 T 23-10-2018 Mlab_1640 e4f43a3d66465b2fbca0ce329812e74d 387 Pfam PF01960 ArgJ family 16 387 5.6E-127 T 23-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Mlab_1640 e4f43a3d66465b2fbca0ce329812e74d 387 Gene3D G3DSA:3.60.70.12 7 256 1.0E-81 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Mlab_1640 e4f43a3d66465b2fbca0ce329812e74d 387 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 7 387 1.5E-128 T 23-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Mlab_1640 e4f43a3d66465b2fbca0ce329812e74d 387 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 387 115.515 T 23-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Mlab_1640 e4f43a3d66465b2fbca0ce329812e74d 387 SUPERFAMILY SSF56266 17 383 1.57E-114 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Mlab_1640 e4f43a3d66465b2fbca0ce329812e74d 387 Gene3D G3DSA:3.10.20.340 257 387 1.1E-41 T 23-10-2018 Mlab_1640 e4f43a3d66465b2fbca0ce329812e74d 387 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 14 387 2.0E-124 T 23-10-2018 Mlab_1287 db6df4ab6d1be122493b9dcd6288298c 459 Gene3D G3DSA:1.20.1720.10 12 224 3.5E-44 T 23-10-2018 Mlab_1287 db6df4ab6d1be122493b9dcd6288298c 459 Pfam PF07690 Major Facilitator Superfamily 18 409 1.8E-49 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_1287 db6df4ab6d1be122493b9dcd6288298c 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 3.3E-5 T 23-10-2018 Mlab_1287 db6df4ab6d1be122493b9dcd6288298c 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 3.3E-5 T 23-10-2018 Mlab_1287 db6df4ab6d1be122493b9dcd6288298c 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 107 127 3.3E-5 T 23-10-2018 Mlab_1287 db6df4ab6d1be122493b9dcd6288298c 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 162 186 3.3E-5 T 23-10-2018 Mlab_1287 db6df4ab6d1be122493b9dcd6288298c 459 SUPERFAMILY SSF103473 5 449 7.06E-61 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_1287 db6df4ab6d1be122493b9dcd6288298c 459 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 415 9.2E-73 T 23-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 Mlab_1287 db6df4ab6d1be122493b9dcd6288298c 459 Gene3D G3DSA:1.20.1250.20 256 454 2.2E-16 T 23-10-2018 Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 Gene3D G3DSA:3.40.50.300 156 307 5.5E-39 T 23-10-2018 Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 Gene3D G3DSA:3.40.50.300 13 126 3.8E-27 T 23-10-2018 Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 427 443 1.4E-28 T 23-10-2018 Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 532 551 1.4E-28 T 23-10-2018 Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 57 76 1.4E-28 T 23-10-2018 Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 555 573 1.4E-28 T 23-10-2018 Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 502 521 1.4E-28 T 23-10-2018 Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 SUPERFAMILY SSF52540 26 401 3.62E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 14 605 1.4E-271 T 23-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 Pfam PF01078 Magnesium chelatase, subunit ChlI 31 84 4.4E-11 T 23-10-2018 IPR000523 Magnesium chelatase ChlI domain Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 Pfam PF13654 AAA domain 170 396 6.5E-19 T 23-10-2018 Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 Gene3D G3DSA:3.30.230.10 416 618 2.6E-64 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 SUPERFAMILY SSF54211 427 598 1.18E-40 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 SMART SM00382 49 305 5.4E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 Gene3D G3DSA:1.10.8.60 308 400 3.0E-38 T 23-10-2018 Mlab_0776 dd037979ad711cfbb0a5a2f01563ada7 632 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 423 600 3.9E-34 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Mlab_1619 f3295e0ab7eea781bd35196a645d19fa 124 Gene3D G3DSA:3.30.70.20 65 124 4.3E-6 T 23-10-2018 Mlab_1619 f3295e0ab7eea781bd35196a645d19fa 124 Gene3D G3DSA:3.30.70.20 15 64 1.1E-8 T 23-10-2018 Mlab_1619 f3295e0ab7eea781bd35196a645d19fa 124 Pfam PF13187 4Fe-4S dicluster domain 41 86 1.9E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_1619 f3295e0ab7eea781bd35196a645d19fa 124 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 42 53 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_1619 f3295e0ab7eea781bd35196a645d19fa 124 SUPERFAMILY SSF54862 25 103 1.05E-18 T 23-10-2018 Mlab_0808 291d37310606ee1803b42aaf0749a6d0 212 Pfam PF01965 DJ-1/PfpI family 3 174 2.1E-24 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 Mlab_0808 291d37310606ee1803b42aaf0749a6d0 212 SUPERFAMILY SSF52317 1 176 9.16E-30 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0808 291d37310606ee1803b42aaf0749a6d0 212 Gene3D G3DSA:3.40.50.880 2 208 2.3E-48 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0609 149c81f1453d4147ddd6ba056d5506cb 374 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 366 4.4E-92 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Mlab_0609 149c81f1453d4147ddd6ba056d5506cb 374 Gene3D G3DSA:3.40.718.10 1 373 2.7E-124 T 23-10-2018 Mlab_0609 149c81f1453d4147ddd6ba056d5506cb 374 SMART SM01329 5 367 1.5E-172 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Mlab_0609 149c81f1453d4147ddd6ba056d5506cb 374 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 263 282 - T 23-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 Mlab_0609 149c81f1453d4147ddd6ba056d5506cb 374 SUPERFAMILY SSF53659 3 369 5.38E-117 T 23-10-2018 Mlab_1208 ff81202b83131e49ca8f9e0127743909 541 Gene3D G3DSA:2.30.130.10 472 541 2.6E-16 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 Mlab_1208 ff81202b83131e49ca8f9e0127743909 541 SMART SM00359 472 540 2.5E-7 T 23-10-2018 IPR002478 PUA domain GO:0003723 Mlab_1208 ff81202b83131e49ca8f9e0127743909 541 SUPERFAMILY SSF88697 478 537 4.54E-13 T 23-10-2018 IPR015947 PUA-like superfamily Mlab_1208 ff81202b83131e49ca8f9e0127743909 541 Gene3D G3DSA:3.40.50.10630 242 408 1.1E-54 T 23-10-2018 Mlab_1208 ff81202b83131e49ca8f9e0127743909 541 SUPERFAMILY SSF51713 92 227 1.07E-26 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Mlab_1208 ff81202b83131e49ca8f9e0127743909 541 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 483 536 4.7E-7 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 Mlab_1208 ff81202b83131e49ca8f9e0127743909 541 Gene3D G3DSA:3.20.20.105 90 230 1.6E-12 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Mlab_1208 ff81202b83131e49ca8f9e0127743909 541 Pfam PF01472 PUA domain 475 537 6.1E-8 T 23-10-2018 IPR002478 PUA domain GO:0003723 Mlab_1208 ff81202b83131e49ca8f9e0127743909 541 SUPERFAMILY SSF52141 257 405 1.1E-47 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Mlab_1206 251ba3d37ab6446a67c3e53fbe983051 188 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 14 186 1.5E-49 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A Mlab_1206 251ba3d37ab6446a67c3e53fbe983051 188 Pfam PF01871 AMMECR1 23 186 2.2E-44 T 23-10-2018 IPR002733 AMMECR1 domain Mlab_1206 251ba3d37ab6446a67c3e53fbe983051 188 SUPERFAMILY SSF143447 2 188 1.57E-58 T 23-10-2018 IPR036071 AMMECR1 domain superfamily Mlab_1206 251ba3d37ab6446a67c3e53fbe983051 188 Gene3D G3DSA:3.30.700.20 10 188 5.8E-55 T 23-10-2018 IPR027485 AMMECR1, N-terminal Mlab_1206 251ba3d37ab6446a67c3e53fbe983051 188 Hamap MF_00645 Protein . 7 184 31.252 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 Mlab_1206 251ba3d37ab6446a67c3e53fbe983051 188 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 3 188 3.2E-55 T 23-10-2018 IPR023473 AMMECR1 Mlab_1206 251ba3d37ab6446a67c3e53fbe983051 188 Gene3D G3DSA:3.30.1490.150 109 182 5.8E-55 T 23-10-2018 Mlab_0493 e9cd9bfb9745838eae24ea9629d99735 193 SUPERFAMILY SSF54211 87 178 3.04E-29 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_0493 e9cd9bfb9745838eae24ea9629d99735 193 SUPERFAMILY SSF54211 1 84 3.29E-29 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_0493 e9cd9bfb9745838eae24ea9629d99735 193 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 23-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Mlab_0493 e9cd9bfb9745838eae24ea9629d99735 193 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 193 37.037 T 23-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Mlab_0493 e9cd9bfb9745838eae24ea9629d99735 193 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 155 167 - T 23-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Mlab_0493 e9cd9bfb9745838eae24ea9629d99735 193 Gene3D G3DSA:3.30.230.40 90 193 1.1E-31 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 Mlab_0493 e9cd9bfb9745838eae24ea9629d99735 193 Gene3D G3DSA:3.30.230.40 1 89 1.3E-33 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 Mlab_0493 e9cd9bfb9745838eae24ea9629d99735 193 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 173 1.0E-56 T 23-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Mlab_1725 a558cfd8f49d763d5454aaf0585389c6 156 Pfam PF12681 Glyoxalase-like domain 3 121 4.8E-44 T 23-10-2018 IPR025870 Glyoxalase-like domain Mlab_1725 a558cfd8f49d763d5454aaf0585389c6 156 SUPERFAMILY SSF54593 1 119 1.24E-24 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Mlab_1725 a558cfd8f49d763d5454aaf0585389c6 156 Gene3D G3DSA:3.10.180.10 1 156 3.0E-66 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Mlab_1599 7818388c9931cb909c73e89ebd1b488a 154 Pfam PF13310 Virulence protein RhuM family 7 120 2.2E-35 T 23-10-2018 IPR011204 Virulence protein RhuM-like Mlab_0816 507d43ea16165c1462c144bbc8caef5e 357 Pfam PF03773 Predicted permease 15 353 3.2E-69 T 23-10-2018 IPR005524 Predicted permease DUF318 Mlab_1443 8a6884d47c1073f8a4dfaabe96861cd7 246 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 246 31.782 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 Mlab_1443 8a6884d47c1073f8a4dfaabe96861cd7 246 Pfam PF02654 Cobalamin-5-phosphate synthase 8 237 1.7E-41 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 Mlab_1443 8a6884d47c1073f8a4dfaabe96861cd7 246 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 238 1.7E-46 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 Mlab_1073 30fbe0b981d05b40f73ee0246383d2ba 599 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 215 6.3E-46 T 23-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 Mlab_1073 30fbe0b981d05b40f73ee0246383d2ba 599 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 1 216 5.0E-71 T 23-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 Mlab_1073 30fbe0b981d05b40f73ee0246383d2ba 599 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 359 558 5.7E-38 T 23-10-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 Mlab_1073 30fbe0b981d05b40f73ee0246383d2ba 599 Pfam PF02361 Cobalt transport protein 352 562 1.2E-36 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component Mlab_1073 30fbe0b981d05b40f73ee0246383d2ba 599 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 1 220 24.659 T 23-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 Mlab_1073 30fbe0b981d05b40f73ee0246383d2ba 599 Gene3D G3DSA:1.10.1760.20 1 214 1.4E-43 T 23-10-2018 Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 28 427 41.79 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 18 425 3.6E-182 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 SUPERFAMILY SSF55481 11 146 5.62E-47 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 Gene3D G3DSA:3.30.960.10 5 146 1.8E-50 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 Gene3D G3DSA:3.30.420.60 148 276 9.5E-42 T 23-10-2018 Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 Gene3D G3DSA:3.30.1330.30 284 428 8.0E-39 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 Pfam PF03465 eRF1 domain 3 286 425 3.2E-27 T 23-10-2018 IPR005142 eRF1 domain 3 Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 Pfam PF03463 eRF1 domain 1 23 143 1.6E-11 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 Pfam PF03464 eRF1 domain 2 150 281 7.3E-37 T 23-10-2018 IPR005141 eRF1 domain 2 Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 SMART SM01194 11 145 1.3E-41 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 SUPERFAMILY SSF55315 286 427 6.47E-35 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like Mlab_1509 18164dd5a3b2c4c58422f5c6a619d77f 428 SUPERFAMILY SSF53137 148 281 1.31E-39 T 23-10-2018 Mlab_1115 c69e1db65c4d4b052deff1f4cc9d0e28 218 Pfam PF01895 PhoU domain 118 200 2.4E-12 T 23-10-2018 IPR026022 PhoU domain Mlab_1115 c69e1db65c4d4b052deff1f4cc9d0e28 218 Pfam PF01895 PhoU domain 20 103 2.8E-15 T 23-10-2018 IPR026022 PhoU domain Mlab_1115 c69e1db65c4d4b052deff1f4cc9d0e28 218 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 210 3.5E-40 T 23-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Mlab_1115 c69e1db65c4d4b052deff1f4cc9d0e28 218 SUPERFAMILY SSF109755 3 213 4.6E-49 T 23-10-2018 Mlab_1115 c69e1db65c4d4b052deff1f4cc9d0e28 218 Gene3D G3DSA:1.20.58.220 1 214 1.2E-45 T 23-10-2018 IPR038078 PhoU-like domain superfamily Mlab_1115 c69e1db65c4d4b052deff1f4cc9d0e28 218 PIRSF PIRSF003107 1 215 2.2E-68 T 23-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Mlab_0855 7f7d8cbbf6aeeba97bc19f8713736345 145 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 15 130 4.8E-42 T 23-10-2018 IPR026350 GxxExxY protein Mlab_0855 7f7d8cbbf6aeeba97bc19f8713736345 145 Pfam PF13366 PD-(D/E)XK nuclease superfamily 15 129 5.9E-41 T 23-10-2018 IPR026350 GxxExxY protein Mlab_0117 02ab6390c4343fd560c99a29f036bdaf 334 Pfam PF13394 4Fe-4S single cluster domain 25 113 3.3E-7 T 23-10-2018 Mlab_0117 02ab6390c4343fd560c99a29f036bdaf 334 SUPERFAMILY SSF102114 19 135 2.88E-14 T 23-10-2018 Mlab_0117 02ab6390c4343fd560c99a29f036bdaf 334 Gene3D G3DSA:3.20.20.70 21 132 4.0E-9 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 153 9.1E-13 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 408 426 9.1E-13 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 265 289 9.1E-13 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 398 420 1.3E-20 T 23-10-2018 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 287 1.3E-20 T 23-10-2018 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 151 1.3E-20 T 23-10-2018 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 370 386 1.3E-20 T 23-10-2018 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 130 430 7.9E-34 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 SUPERFAMILY SSF51971 128 379 1.12E-70 T 23-10-2018 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 Gene3D G3DSA:3.50.50.60 254 351 2.1E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 Gene3D G3DSA:1.10.1060.10 2 130 4.4E-40 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 9 118 5.0E-43 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 Gene3D G3DSA:3.50.50.60 357 445 4.1E-7 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 Gene3D G3DSA:3.50.50.60 131 253 3.0E-36 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 SUPERFAMILY SSF46548 3 140 2.98E-33 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Mlab_1112 4dca314e0c96398d6d8f446ba256583b 446 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 7 442 3.7E-166 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 Mlab_1460 a37f2ae7b767865d56c7b6603a720af1 451 Pfam PF00801 PKD domain 214 262 1.4E-6 T 23-10-2018 IPR000601 PKD domain Mlab_1460 a37f2ae7b767865d56c7b6603a720af1 451 SMART SM00089 204 281 3.3E-4 T 23-10-2018 IPR022409 PKD/Chitinase domain Mlab_1460 a37f2ae7b767865d56c7b6603a720af1 451 Gene3D G3DSA:2.60.120.200 279 448 1.9E-5 T 23-10-2018 Mlab_1460 a37f2ae7b767865d56c7b6603a720af1 451 SUPERFAMILY SSF49299 215 280 1.57E-8 T 23-10-2018 IPR035986 PKD domain superfamily Mlab_1460 a37f2ae7b767865d56c7b6603a720af1 451 SUPERFAMILY SSF49899 280 442 5.07E-7 T 23-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Mlab_1460 a37f2ae7b767865d56c7b6603a720af1 451 Gene3D G3DSA:2.60.40.10 209 278 8.6E-9 T 23-10-2018 IPR013783 Immunoglobulin-like fold Mlab_1460 a37f2ae7b767865d56c7b6603a720af1 451 Pfam PF07790 Archaeal Type IV pilin, N-terminal 37 107 1.8E-13 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_1234 3f412471433cdc4e4557b945a31ed78f 198 SUPERFAMILY SSF55821 8 185 5.19E-53 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Mlab_1234 3f412471433cdc4e4557b945a31ed78f 198 Gene3D G3DSA:3.90.870.10 2 195 1.0E-59 T 23-10-2018 Mlab_1234 3f412471433cdc4e4557b945a31ed78f 198 Pfam PF01300 Telomere recombination 16 178 4.2E-42 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 Mlab_1234 3f412471433cdc4e4557b945a31ed78f 198 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 191 8.1E-49 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 Mlab_1316 fc273feff4441c74186aa58bf4ec280e 407 Gene3D G3DSA:3.20.20.70 11 261 4.0E-13 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1316 fc273feff4441c74186aa58bf4ec280e 407 SUPERFAMILY SSF102114 34 233 2.55E-14 T 23-10-2018 Mlab_1316 fc273feff4441c74186aa58bf4ec280e 407 Pfam PF04055 Radical SAM superfamily 13 191 5.8E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_1316 fc273feff4441c74186aa58bf4ec280e 407 TIGRFAM TIGR03278 methan_mark_10: methanogenesis marker radical SAM protein 8 404 3.7E-167 T 23-10-2018 IPR017672 Putative methanogenesis marker protein 10 Mlab_1210 bd19f0f11bec8f7b101564384ce41140 140 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 7 121 2.2E-35 T 23-10-2018 IPR026350 GxxExxY protein Mlab_1210 bd19f0f11bec8f7b101564384ce41140 140 Pfam PF13366 PD-(D/E)XK nuclease superfamily 6 119 1.5E-35 T 23-10-2018 IPR026350 GxxExxY protein Mlab_1343 37dae3f82b8c4a004f7592a606afb963 214 Pfam PF01876 RNase P subunit p30 73 195 1.2E-15 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Mlab_1343 37dae3f82b8c4a004f7592a606afb963 214 SUPERFAMILY SSF89550 14 195 1.22E-17 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Mlab_1343 37dae3f82b8c4a004f7592a606afb963 214 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 108 195 3.0E-7 T 23-10-2018 Mlab_1343 37dae3f82b8c4a004f7592a606afb963 214 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 8 207 24.635 T 23-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 Mlab_1343 37dae3f82b8c4a004f7592a606afb963 214 Gene3D G3DSA:3.20.20.140 37 204 6.1E-32 T 23-10-2018 Mlab_0160 de54fa08d8bc0fb4e03243732d7446e9 317 SUPERFAMILY SSF47413 129 183 1.1E-10 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Mlab_0160 de54fa08d8bc0fb4e03243732d7446e9 317 SMART SM00530 131 185 3.0E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_0160 de54fa08d8bc0fb4e03243732d7446e9 317 Pfam PF01381 Helix-turn-helix 132 179 6.1E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_0160 de54fa08d8bc0fb4e03243732d7446e9 317 Gene3D G3DSA:1.10.260.40 126 210 1.6E-9 T 23-10-2018 Mlab_0160 de54fa08d8bc0fb4e03243732d7446e9 317 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 2 308 24.587 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 Mlab_1630 1ad5ba3cc4e99d221b02617a903f0bd8 63 Pfam PF01381 Helix-turn-helix 5 59 8.5E-16 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_1630 1ad5ba3cc4e99d221b02617a903f0bd8 63 Gene3D G3DSA:1.10.260.40 1 63 5.2E-28 T 23-10-2018 Mlab_1630 1ad5ba3cc4e99d221b02617a903f0bd8 63 SMART SM00530 4 59 7.6E-16 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_1630 1ad5ba3cc4e99d221b02617a903f0bd8 63 SUPERFAMILY SSF47413 2 61 3.75E-18 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Mlab_0572 fc1ad060291dae8b4e3601b173546503 361 SUPERFAMILY SSF56762 17 361 7.85E-92 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0572 fc1ad060291dae8b4e3601b173546503 361 Gene3D G3DSA:1.10.645.20 7 361 7.8E-99 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0572 fc1ad060291dae8b4e3601b173546503 361 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 124 282 2.4E-38 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0572 fc1ad060291dae8b4e3601b173546503 361 Pfam PF00374 Nickel-dependent hydrogenase 45 116 1.2E-13 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 Mlab_1748 ab15a394d7b73882f193bacc495aee79 310 Pfam PF00805 Pentapeptide repeats (8 copies) 103 139 1.2E-7 T 23-10-2018 IPR001646 Pentapeptide repeat Mlab_1748 ab15a394d7b73882f193bacc495aee79 310 Pfam PF00805 Pentapeptide repeats (8 copies) 66 99 1.6E-8 T 23-10-2018 IPR001646 Pentapeptide repeat Mlab_1748 ab15a394d7b73882f193bacc495aee79 310 Gene3D G3DSA:2.160.20.80 50 176 8.2E-23 T 23-10-2018 Mlab_1748 ab15a394d7b73882f193bacc495aee79 310 SUPERFAMILY SSF141571 46 145 2.22E-21 T 23-10-2018 Mlab_1632 f9ee41da9c27e855b50acb9536f1eaa9 612 SUPERFAMILY SSF102114 293 550 3.53E-11 T 23-10-2018 Mlab_1632 f9ee41da9c27e855b50acb9536f1eaa9 612 Pfam PF04055 Radical SAM superfamily 309 500 7.8E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_1632 f9ee41da9c27e855b50acb9536f1eaa9 612 Pfam PF08497 Radical SAM N-terminal 15 307 9.6E-110 T 23-10-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal Mlab_1632 f9ee41da9c27e855b50acb9536f1eaa9 612 SMART SM00729 304 553 6.7E-7 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_1632 f9ee41da9c27e855b50acb9536f1eaa9 612 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 308 328 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Mlab_1632 f9ee41da9c27e855b50acb9536f1eaa9 612 Gene3D G3DSA:3.80.30.20 305 544 1.1E-10 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Mlab_1632 f9ee41da9c27e855b50acb9536f1eaa9 612 Pfam PF11842 Domain of unknown function (DUF3362) 521 591 3.2E-20 T 23-10-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal Mlab_1632 f9ee41da9c27e855b50acb9536f1eaa9 612 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 15 566 1.3E-232 T 23-10-2018 IPR022946 Uncharacterised protein family UPF0313 Mlab_1632 f9ee41da9c27e855b50acb9536f1eaa9 612 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 15 567 49.895 T 23-10-2018 IPR022946 Uncharacterised protein family UPF0313 Mlab_0498 7849849219f173573d5fcecc66e3564e 476 Gene3D G3DSA:1.10.8.60 159 219 6.8E-11 T 23-10-2018 Mlab_0498 7849849219f173573d5fcecc66e3564e 476 SMART SM00382 35 157 3.3E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0498 7849849219f173573d5fcecc66e3564e 476 SUPERFAMILY SSF52540 2 218 1.8E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0498 7849849219f173573d5fcecc66e3564e 476 Hamap MF_01508 Replication factor C large subunit [rfcL]. 1 438 29.445 T 23-10-2018 IPR023935 Replication factor C, large subunit Mlab_0498 7849849219f173573d5fcecc66e3564e 476 Gene3D G3DSA:3.40.50.300 2 155 4.0E-36 T 23-10-2018 Mlab_0498 7849849219f173573d5fcecc66e3564e 476 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 39 125 8.1E-11 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_1069 8f3e67ce578245ba0325b5d10102169d 421 Gene3D G3DSA:3.30.559.10 11 161 3.4E-5 T 23-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Mlab_1069 8f3e67ce578245ba0325b5d10102169d 421 SUPERFAMILY SSF52777 14 156 6.45E-11 T 23-10-2018 Mlab_1069 8f3e67ce578245ba0325b5d10102169d 421 SUPERFAMILY SSF52777 200 310 8.34E-7 T 23-10-2018 Mlab_0522 668f43adc6efa7cde96b083f4398225a 204 SUPERFAMILY SSF75615 113 189 7.72E-10 T 23-10-2018 Mlab_0522 668f43adc6efa7cde96b083f4398225a 204 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 2 175 2.4E-20 T 23-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Mlab_0522 668f43adc6efa7cde96b083f4398225a 204 Pfam PF13241 Putative NAD(P)-binding 4 107 3.7E-19 T 23-10-2018 Mlab_0522 668f43adc6efa7cde96b083f4398225a 204 Gene3D G3DSA:3.40.50.720 1 128 3.5E-22 T 23-10-2018 Mlab_0522 668f43adc6efa7cde96b083f4398225a 204 SUPERFAMILY SSF51735 1 104 2.93E-12 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0842 553213fd1b286ddbd89496d7b99f1997 446 SUPERFAMILY SSF116734 5 212 7.85E-35 T 23-10-2018 Mlab_0842 553213fd1b286ddbd89496d7b99f1997 446 Gene3D G3DSA:3.90.220.20 224 357 3.4E-21 T 23-10-2018 Mlab_0842 553213fd1b286ddbd89496d7b99f1997 446 Gene3D G3DSA:3.90.220.20 8 210 6.3E-31 T 23-10-2018 Mlab_0842 553213fd1b286ddbd89496d7b99f1997 446 SUPERFAMILY SSF116734 216 412 5.23E-35 T 23-10-2018 Mlab_0842 553213fd1b286ddbd89496d7b99f1997 446 Gene3D G3DSA:1.10.287.1120 360 446 5.9E-5 T 23-10-2018 Mlab_0842 553213fd1b286ddbd89496d7b99f1997 446 Pfam PF01420 Type I restriction modification DNA specificity domain 230 385 1.1E-11 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 Mlab_0842 553213fd1b286ddbd89496d7b99f1997 446 Pfam PF01420 Type I restriction modification DNA specificity domain 20 193 3.8E-7 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 Pfam PF03129 Anticodon binding domain 290 382 4.1E-16 T 23-10-2018 IPR004154 Anticodon-binding Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 411 477 1.1E-11 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 Hamap MF_01571 Proline--tRNA ligase [proS]. 7 477 38.003 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 103 273 7.6E-24 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 Gene3D G3DSA:3.30.110.30 404 475 6.4E-13 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 SMART SM00946 410 477 2.4E-20 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 Gene3D G3DSA:3.40.50.800 285 401 2.3E-31 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 Gene3D G3DSA:3.30.930.10 13 283 6.0E-85 T 23-10-2018 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 SUPERFAMILY SSF52954 278 402 3.62E-31 T 23-10-2018 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 SUPERFAMILY SSF55681 13 277 1.51E-76 T 23-10-2018 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 10 477 6.4E-175 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 SUPERFAMILY SSF64586 405 477 3.53E-13 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 2.9E-11 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 2.9E-11 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 2.9E-11 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Mlab_1386 a24c92ac06d7680d1b6d89bd77ea99fd 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 2.9E-11 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Mlab_0101 b2b2470b25d618522105385848e7ba1d 205 Gene3D G3DSA:3.30.230.10 112 200 9.4E-31 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Mlab_0101 b2b2470b25d618522105385848e7ba1d 205 ProSitePatterns PS00585 Ribosomal protein S5 signature. 66 98 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site Mlab_0101 b2b2470b25d618522105385848e7ba1d 205 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 1 201 46.079 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0101 b2b2470b25d618522105385848e7ba1d 205 SUPERFAMILY SSF54211 127 197 1.14E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_0101 b2b2470b25d618522105385848e7ba1d 205 Gene3D G3DSA:3.30.160.770 7 111 1.3E-34 T 23-10-2018 Mlab_0101 b2b2470b25d618522105385848e7ba1d 205 Pfam PF00333 Ribosomal protein S5, N-terminal domain 49 113 1.8E-23 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 Mlab_0101 b2b2470b25d618522105385848e7ba1d 205 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 4 200 4.3E-90 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0101 b2b2470b25d618522105385848e7ba1d 205 SUPERFAMILY SSF54768 44 114 2.41E-20 T 23-10-2018 Mlab_0101 b2b2470b25d618522105385848e7ba1d 205 Pfam PF03719 Ribosomal protein S5, C-terminal domain 134 197 3.6E-21 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 Mlab_0995 681bbbd7e565b94858ec53cc7f9d101f 349 Gene3D G3DSA:2.40.30.40 69 161 3.4E-124 T 23-10-2018 IPR023367 Peptidase M42, domain 2 Mlab_0995 681bbbd7e565b94858ec53cc7f9d101f 349 PIRSF PIRSF001123 4 348 2.2E-122 T 23-10-2018 IPR008007 Peptidase M42 Mlab_0995 681bbbd7e565b94858ec53cc7f9d101f 349 SUPERFAMILY SSF101821 70 178 6.26E-31 T 23-10-2018 Mlab_0995 681bbbd7e565b94858ec53cc7f9d101f 349 Gene3D G3DSA:3.40.630.10 9 338 3.4E-124 T 23-10-2018 Mlab_0995 681bbbd7e565b94858ec53cc7f9d101f 349 SUPERFAMILY SSF53187 8 345 4.11E-63 T 23-10-2018 Mlab_0995 681bbbd7e565b94858ec53cc7f9d101f 349 Pfam PF05343 M42 glutamyl aminopeptidase 47 338 1.1E-103 T 23-10-2018 IPR008007 Peptidase M42 Mlab_0651 693b3597a3e9cedfc6a36867826aceb8 47 SUPERFAMILY SSF57829 3 46 9.89E-16 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Mlab_0651 693b3597a3e9cedfc6a36867826aceb8 47 Gene3D G3DSA:2.20.28.70 1 47 3.8E-18 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 Mlab_0651 693b3597a3e9cedfc6a36867826aceb8 47 SMART SM01377 1 45 5.7E-11 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 Mlab_0651 693b3597a3e9cedfc6a36867826aceb8 47 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 1 46 17.0 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 Mlab_0651 693b3597a3e9cedfc6a36867826aceb8 47 Pfam PF01020 Ribosomal L40e family 14 43 6.9E-7 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 Mlab_1219 938e94946e89a9e7ad4f0c3b1f9bfa20 192 Pfam PF01991 ATP synthase (E/31 kDa) subunit 9 191 9.8E-14 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1219 938e94946e89a9e7ad4f0c3b1f9bfa20 192 Gene3D G3DSA:3.30.2320.30 101 192 2.6E-7 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1219 938e94946e89a9e7ad4f0c3b1f9bfa20 192 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 1 192 13.139 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1219 938e94946e89a9e7ad4f0c3b1f9bfa20 192 SUPERFAMILY SSF160527 80 192 2.09E-15 T 23-10-2018 Mlab_1219 938e94946e89a9e7ad4f0c3b1f9bfa20 192 Gene3D G3DSA:1.20.5.620 6 99 7.8E-8 T 23-10-2018 Mlab_1006 f76c424d36766426388e076ac8a3d8b2 165 Gene3D G3DSA:3.40.50.620 1 150 9.7E-37 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_1006 f76c424d36766426388e076ac8a3d8b2 165 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 62 2.3E-10 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Mlab_1006 f76c424d36766426388e076ac8a3d8b2 165 Pfam PF01467 Cytidylyltransferase-like 5 139 5.9E-9 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Mlab_1006 f76c424d36766426388e076ac8a3d8b2 165 SUPERFAMILY SSF52374 3 141 4.29E-16 T 23-10-2018 Mlab_1715 7795a3cdc649a240300b565ff68d09eb 314 Pfam PF01544 CorA-like Mg2+ transporter protein 23 311 6.6E-58 T 23-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 Mlab_1715 7795a3cdc649a240300b565ff68d09eb 314 SUPERFAMILY SSF143865 1 249 1.83E-46 T 23-10-2018 Mlab_1715 7795a3cdc649a240300b565ff68d09eb 314 Gene3D G3DSA:3.30.460.20 2 133 1.5E-16 T 23-10-2018 Mlab_1715 7795a3cdc649a240300b565ff68d09eb 314 Gene3D G3DSA:1.20.58.340 134 256 1.2E-26 T 23-10-2018 Mlab_1715 7795a3cdc649a240300b565ff68d09eb 314 SUPERFAMILY SSF144083 250 311 1.83E-12 T 23-10-2018 Mlab_1715 7795a3cdc649a240300b565ff68d09eb 314 Gene3D G3DSA:1.20.58.340 258 314 1.5E-7 T 23-10-2018 Mlab_1405 6fa29f69674fabe060156d961146df21 671 SUPERFAMILY SSF88723 1 129 5.89E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily Mlab_1405 6fa29f69674fabe060156d961146df21 671 Pfam PF00437 Type II/IV secretion system protein 215 382 2.3E-11 T 23-10-2018 IPR001482 Type II/IV secretion system protein Mlab_1405 6fa29f69674fabe060156d961146df21 671 SUPERFAMILY SSF54814 521 580 8.5E-6 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Mlab_1405 6fa29f69674fabe060156d961146df21 671 Gene3D G3DSA:3.40.50.1010 2 127 7.5E-35 T 23-10-2018 Mlab_1405 6fa29f69674fabe060156d961146df21 671 Pfam PF01850 PIN domain 4 118 4.5E-6 T 23-10-2018 IPR002716 PIN domain Mlab_1405 6fa29f69674fabe060156d961146df21 671 SUPERFAMILY SSF52540 191 386 2.24E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1405 6fa29f69674fabe060156d961146df21 671 Gene3D G3DSA:3.40.50.300 238 393 7.8E-18 T 23-10-2018 Mlab_1405 6fa29f69674fabe060156d961146df21 671 SMART SM00670 1 115 2.8E-20 T 23-10-2018 IPR002716 PIN domain Mlab_1516 e3acc9134f3ceb38512f0d9913d47e6f 125 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 1 125 29.382 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1516 e3acc9134f3ceb38512f0d9913d47e6f 125 Gene3D G3DSA:2.40.10.310 58 125 6.7E-31 T 23-10-2018 Mlab_1516 e3acc9134f3ceb38512f0d9913d47e6f 125 Pfam PF01201 Ribosomal protein S8e 3 124 2.2E-36 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 Mlab_1516 e3acc9134f3ceb38512f0d9913d47e6f 125 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 125 3.7E-50 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1516 e3acc9134f3ceb38512f0d9913d47e6f 125 ProSitePatterns PS01193 Ribosomal protein S8e signature. 9 28 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0264 a153c982b19454e8277ff52deeed537f 211 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 85 182 7.8E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_0264 a153c982b19454e8277ff52deeed537f 211 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 180 9.8E-31 T 23-10-2018 Mlab_0264 a153c982b19454e8277ff52deeed537f 211 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 6.5E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_0264 a153c982b19454e8277ff52deeed537f 211 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 6.5E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_0264 a153c982b19454e8277ff52deeed537f 211 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 127 143 6.5E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_0264 a153c982b19454e8277ff52deeed537f 211 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 6.5E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_0264 a153c982b19454e8277ff52deeed537f 211 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 89 178 3.6E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_0264 a153c982b19454e8277ff52deeed537f 211 Gene3D G3DSA:1.10.150.520 18 84 4.5E-37 T 23-10-2018 Mlab_0264 a153c982b19454e8277ff52deeed537f 211 Gene3D G3DSA:3.40.50.1000 6 193 4.5E-37 T 23-10-2018 IPR023214 HAD superfamily Mlab_0264 a153c982b19454e8277ff52deeed537f 211 SUPERFAMILY SSF56784 5 209 3.53E-41 T 23-10-2018 IPR036412 HAD-like superfamily Mlab_1721 af07c28c9b23784bca30e4adb6d58053 351 SUPERFAMILY SSF53807 36 345 3.49E-58 T 23-10-2018 Mlab_1721 af07c28c9b23784bca30e4adb6d58053 351 Gene3D G3DSA:3.40.50.1980 22 343 6.2E-78 T 23-10-2018 Mlab_1721 af07c28c9b23784bca30e4adb6d58053 351 Pfam PF01497 Periplasmic binding protein 59 281 5.6E-26 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain Mlab_1492 cc5cf2490fed2185bcb0fe47443cbaa0 436 Pfam PF01593 Flavin containing amine oxidoreductase 33 429 3.1E-24 T 23-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 Mlab_1492 cc5cf2490fed2185bcb0fe47443cbaa0 436 Gene3D G3DSA:3.50.50.60 18 436 6.8E-28 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_1492 cc5cf2490fed2185bcb0fe47443cbaa0 436 SUPERFAMILY SSF51905 24 431 6.04E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0633 fe41f5c2ec1050051255a925669bc91c 384 TIGRFAM TIGR03540 DapC_direct: LL-diaminopimelate aminotransferase 2 379 2.5E-189 T 23-10-2018 IPR019881 Diaminopimelate aminotransferase, DapL, Desulfovibrio-type GO:0009089|GO:0010285 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097 Mlab_0633 fe41f5c2ec1050051255a925669bc91c 384 Pfam PF00155 Aminotransferase class I and II 30 376 2.0E-59 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Mlab_0633 fe41f5c2ec1050051255a925669bc91c 384 Gene3D G3DSA:3.90.1150.10 20 377 5.9E-131 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_0633 fe41f5c2ec1050051255a925669bc91c 384 Gene3D G3DSA:3.40.640.10 41 282 5.9E-131 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_0633 fe41f5c2ec1050051255a925669bc91c 384 SUPERFAMILY SSF53383 2 379 1.36E-112 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_0633 fe41f5c2ec1050051255a925669bc91c 384 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Mlab_1091 7ed9138534b91762a329188a5212f929 337 Pfam PF01497 Periplasmic binding protein 21 269 3.7E-24 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain Mlab_1091 7ed9138534b91762a329188a5212f929 337 Gene3D G3DSA:3.40.50.1980 139 337 1.1E-56 T 23-10-2018 Mlab_1091 7ed9138534b91762a329188a5212f929 337 Gene3D G3DSA:3.40.50.1980 1 138 2.6E-35 T 23-10-2018 Mlab_1091 7ed9138534b91762a329188a5212f929 337 SUPERFAMILY SSF53807 2 293 1.33E-43 T 23-10-2018 Mlab_0361 694c329a49d4aa0ca554580c23ac6147 434 SUPERFAMILY SSF56731 165 234 6.8E-9 T 23-10-2018 Mlab_0361 694c329a49d4aa0ca554580c23ac6147 434 SMART SM00493 171 240 3.7E-7 T 23-10-2018 IPR006171 TOPRIM domain Mlab_0361 694c329a49d4aa0ca554580c23ac6147 434 Hamap MF_00007 DNA primase DnaG [dnaG]. 7 434 31.223 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 Mlab_0361 694c329a49d4aa0ca554580c23ac6147 434 Pfam PF13662 Toprim domain 171 238 9.0E-11 T 23-10-2018 IPR006171 TOPRIM domain Mlab_0361 694c329a49d4aa0ca554580c23ac6147 434 Gene3D G3DSA:3.40.1360.10 166 264 1.1E-12 T 23-10-2018 Mlab_0263 019a32cf106d830601b0d8db721fa8b2 194 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 40 47 - T 23-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Mlab_0263 019a32cf106d830601b0d8db721fa8b2 194 Pfam PF00484 Carbonic anhydrase 35 189 1.2E-48 T 23-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Mlab_0263 019a32cf106d830601b0d8db721fa8b2 194 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 80 100 - T 23-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Mlab_0263 019a32cf106d830601b0d8db721fa8b2 194 SMART SM00947 28 194 2.3E-58 T 23-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Mlab_0263 019a32cf106d830601b0d8db721fa8b2 194 Gene3D G3DSA:3.40.1050.10 1 194 5.7E-63 T 23-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 Mlab_0263 019a32cf106d830601b0d8db721fa8b2 194 SUPERFAMILY SSF53056 2 193 1.31E-56 T 23-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 Mlab_0078 2e881d8a48d0af39f62b7f1b4b2e7865 189 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 183 7.8E-68 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Mlab_0078 2e881d8a48d0af39f62b7f1b4b2e7865 189 SUPERFAMILY SSF52317 2 185 3.55E-47 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0078 2e881d8a48d0af39f62b7f1b4b2e7865 189 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 23-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Mlab_0078 2e881d8a48d0af39f62b7f1b4b2e7865 189 PIRSF PIRSF005639 1 189 6.1E-67 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Mlab_0078 2e881d8a48d0af39f62b7f1b4b2e7865 189 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 184 35.692 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Mlab_0078 2e881d8a48d0af39f62b7f1b4b2e7865 189 Gene3D G3DSA:3.40.50.880 1 189 1.7E-66 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0078 2e881d8a48d0af39f62b7f1b4b2e7865 189 Pfam PF01174 SNO glutamine amidotransferase family 5 185 3.6E-54 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Mlab_0571 1a37251e2489db497e6eeac19b5c0ce8 159 Gene3D G3DSA:3.40.50.12280 1 157 2.1E-38 T 23-10-2018 Mlab_0571 1a37251e2489db497e6eeac19b5c0ce8 159 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 26 136 2.2E-21 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0571 1a37251e2489db497e6eeac19b5c0ce8 159 SUPERFAMILY SSF56770 3 146 1.31E-45 T 23-10-2018 Mlab_1136 f6bbbe145e9b7f8fec34f62f2cdb2924 147 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 5 131 8.9E-27 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_1136 f6bbbe145e9b7f8fec34f62f2cdb2924 147 Pfam PF01750 Hydrogenase maturation protease 21 128 2.9E-15 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_1136 f6bbbe145e9b7f8fec34f62f2cdb2924 147 PRINTS PR00446 Hydrogen uptake protein signature 54 64 2.6E-10 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_1136 f6bbbe145e9b7f8fec34f62f2cdb2924 147 PRINTS PR00446 Hydrogen uptake protein signature 65 81 2.6E-10 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_1136 f6bbbe145e9b7f8fec34f62f2cdb2924 147 PRINTS PR00446 Hydrogen uptake protein signature 3 15 2.6E-10 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_1136 f6bbbe145e9b7f8fec34f62f2cdb2924 147 PRINTS PR00446 Hydrogen uptake protein signature 15 26 2.6E-10 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Mlab_1136 f6bbbe145e9b7f8fec34f62f2cdb2924 147 SUPERFAMILY SSF53163 1 131 5.49E-28 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily Mlab_1136 f6bbbe145e9b7f8fec34f62f2cdb2924 147 Gene3D G3DSA:3.40.50.1450 1 143 5.0E-41 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily Mlab_0594 ee82dbc828b4ed0cba29d7ec9a4864df 251 Gene3D G3DSA:3.40.50.80 89 189 6.2E-23 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Mlab_0594 ee82dbc828b4ed0cba29d7ec9a4864df 251 Gene3D G3DSA:2.40.30.10 6 87 1.6E-10 T 23-10-2018 Mlab_0594 ee82dbc828b4ed0cba29d7ec9a4864df 251 PIRSF PIRSF006816 2 240 2.7E-68 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 Mlab_0594 ee82dbc828b4ed0cba29d7ec9a4864df 251 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 201 234 4.4E-11 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain Mlab_0594 ee82dbc828b4ed0cba29d7ec9a4864df 251 Gene3D G3DSA:2.10.240.10 201 235 4.1E-5 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily Mlab_0594 ee82dbc828b4ed0cba29d7ec9a4864df 251 SUPERFAMILY SSF52343 83 233 4.06E-29 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Mlab_0594 ee82dbc828b4ed0cba29d7ec9a4864df 251 SUPERFAMILY SSF63380 5 88 9.68E-18 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Mlab_1108 6985666e67b65444d874215b51d5880d 268 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 7 258 6.4E-64 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 Mlab_1108 6985666e67b65444d874215b51d5880d 268 Gene3D G3DSA:1.10.4200.10 26 265 4.5E-67 T 23-10-2018 Mlab_1393 adc496e0add0739509ebb63db7183507 274 SUPERFAMILY SSF51366 15 264 8.57E-87 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_1393 adc496e0add0739509ebb63db7183507 274 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 23-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Mlab_1393 adc496e0add0739509ebb63db7183507 274 Gene3D G3DSA:3.20.20.70 8 266 2.9E-97 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1393 adc496e0add0739509ebb63db7183507 274 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 12 264 36.758 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Mlab_1393 adc496e0add0739509ebb63db7183507 274 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 18 262 3.9E-92 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Mlab_1393 adc496e0add0739509ebb63db7183507 274 Pfam PF00290 Tryptophan synthase alpha chain 16 265 2.9E-88 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Mlab_1455 39b4137a17487934faf2a26a06230266 144 Pfam PF01842 ACT domain 76 124 1.7E-7 T 23-10-2018 IPR002912 ACT domain Mlab_1455 39b4137a17487934faf2a26a06230266 144 Gene3D G3DSA:3.30.2130.10 2 143 1.8E-39 T 23-10-2018 Mlab_1455 39b4137a17487934faf2a26a06230266 144 SUPERFAMILY SSF55021 75 140 6.55E-13 T 23-10-2018 Mlab_1455 39b4137a17487934faf2a26a06230266 144 SUPERFAMILY SSF55021 6 72 8.74E-11 T 23-10-2018 Mlab_0450 2a9f26053c3897e4aa84d504d4b9f047 124 PRINTS PR00332 Histidine triad family signature 19 37 4.5E-5 T 23-10-2018 IPR001310 Histidine triad (HIT) protein Mlab_0450 2a9f26053c3897e4aa84d504d4b9f047 124 PRINTS PR00332 Histidine triad family signature 86 96 4.5E-5 T 23-10-2018 IPR001310 Histidine triad (HIT) protein Mlab_0450 2a9f26053c3897e4aa84d504d4b9f047 124 SUPERFAMILY SSF54197 1 110 6.66E-37 T 23-10-2018 IPR036265 HIT-like superfamily Mlab_0450 2a9f26053c3897e4aa84d504d4b9f047 124 Gene3D G3DSA:3.30.428.10 1 118 1.3E-36 T 23-10-2018 IPR036265 HIT-like superfamily Mlab_0450 2a9f26053c3897e4aa84d504d4b9f047 124 Pfam PF01230 HIT domain 9 100 3.4E-21 T 23-10-2018 IPR001310 Histidine triad (HIT) protein Mlab_1147 1e44ee38d827ebc9bbaa836fca81e8c3 199 Pfam PF01928 CYTH domain 17 163 2.4E-22 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 Mlab_1147 1e44ee38d827ebc9bbaa836fca81e8c3 199 Gene3D G3DSA:2.40.320.10 9 199 2.3E-37 T 23-10-2018 Mlab_1147 1e44ee38d827ebc9bbaa836fca81e8c3 199 SMART SM01118 16 195 1.1E-22 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 Mlab_1147 1e44ee38d827ebc9bbaa836fca81e8c3 199 SUPERFAMILY SSF55154 17 193 1.8E-33 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 Mlab_1147 1e44ee38d827ebc9bbaa836fca81e8c3 199 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 17 193 1.9E-39 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 Mlab_1147 1e44ee38d827ebc9bbaa836fca81e8c3 199 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 17 157 2.0E-26 T 23-10-2018 Mlab_1036 1447262083ca5c7a0b20f1ef56d8c188 188 Pfam PF09851 Short C-terminal domain 160 187 3.1E-10 T 23-10-2018 IPR018649 SHOCT domain Mlab_1712 e5905a13f8b5d8b9e4294b8f3c2742da 393 SUPERFAMILY SSF49265 83 219 2.55E-11 T 23-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 Mlab_1712 e5905a13f8b5d8b9e4294b8f3c2742da 393 Gene3D G3DSA:2.60.40.10 131 226 1.7E-6 T 23-10-2018 IPR013783 Immunoglobulin-like fold Mlab_1712 e5905a13f8b5d8b9e4294b8f3c2742da 393 Gene3D G3DSA:2.60.40.10 27 127 3.6E-5 T 23-10-2018 IPR013783 Immunoglobulin-like fold Mlab_0766 449798967826235888f3e1ecac4fec16 259 TIGRFAM TIGR03855 NAD_NadX: aspartate dehydrogenase 30 257 1.8E-83 T 23-10-2018 IPR022487 L-aspartate dehydrogenase, archaeal GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 Mlab_0766 449798967826235888f3e1ecac4fec16 259 Pfam PF01958 Domain of unknown function DUF108 163 245 4.2E-28 T 23-10-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 Mlab_0766 449798967826235888f3e1ecac4fec16 259 Gene3D G3DSA:3.30.360.10 126 232 2.9E-70 T 23-10-2018 Mlab_0766 449798967826235888f3e1ecac4fec16 259 PIRSF PIRSF005227 6 259 4.1E-71 T 23-10-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 Mlab_0766 449798967826235888f3e1ecac4fec16 259 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 123 4.4E-16 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 Mlab_0766 449798967826235888f3e1ecac4fec16 259 SUPERFAMILY SSF51735 9 146 1.15E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0766 449798967826235888f3e1ecac4fec16 259 SUPERFAMILY SSF55347 126 227 6.54E-21 T 23-10-2018 Mlab_0766 449798967826235888f3e1ecac4fec16 259 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 8 257 28.791 T 23-10-2018 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 Mlab_0766 449798967826235888f3e1ecac4fec16 259 Gene3D G3DSA:3.40.50.720 11 249 2.9E-70 T 23-10-2018 Mlab_0399 1b0842e1e73afc3d9fb9f9762953a5d8 314 Gene3D G3DSA:3.10.340.11 2 169 1.1E-123 T 23-10-2018 Mlab_0399 1b0842e1e73afc3d9fb9f9762953a5d8 314 TIGRFAM TIGR03120 one_C_mch: methenyltetrahydromethanopterin cyclohydrolase 3 312 9.5E-132 T 23-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 Mlab_0399 1b0842e1e73afc3d9fb9f9762953a5d8 314 Pfam PF02289 Cyclohydrolase (MCH) 3 311 1.1E-128 T 23-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 Mlab_0399 1b0842e1e73afc3d9fb9f9762953a5d8 314 Gene3D G3DSA:3.30.1030.10 45 306 1.1E-123 T 23-10-2018 Mlab_0399 1b0842e1e73afc3d9fb9f9762953a5d8 314 Hamap MF_00486 Methenyltetrahydromethanopterin cyclohydrolase [mch]. 1 314 155.25 T 23-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 Mlab_0399 1b0842e1e73afc3d9fb9f9762953a5d8 314 SUPERFAMILY SSF56199 2 313 6.41E-113 T 23-10-2018 Mlab_0043 0ffbccfa78443e48001f2b57ddefcb38 269 Gene3D G3DSA:1.10.3720.10 53 265 4.2E-20 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0043 0ffbccfa78443e48001f2b57ddefcb38 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 264 2.0E-22 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_0043 0ffbccfa78443e48001f2b57ddefcb38 269 SUPERFAMILY SSF161098 60 252 6.02E-25 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0309 6a0f5b19be6354ca13e1161fa2979f00 142 SUPERFAMILY SSF52402 2 141 1.59E-36 T 23-10-2018 Mlab_0309 6a0f5b19be6354ca13e1161fa2979f00 142 PRINTS PR01438 Universal stress protein signature 2 20 1.6E-17 T 23-10-2018 IPR006015 Universal stress protein A Mlab_0309 6a0f5b19be6354ca13e1161fa2979f00 142 PRINTS PR01438 Universal stress protein signature 119 141 1.6E-17 T 23-10-2018 IPR006015 Universal stress protein A Mlab_0309 6a0f5b19be6354ca13e1161fa2979f00 142 PRINTS PR01438 Universal stress protein signature 101 113 1.6E-17 T 23-10-2018 IPR006015 Universal stress protein A Mlab_0309 6a0f5b19be6354ca13e1161fa2979f00 142 PIRSF PIRSF006276 1 142 1.3E-19 T 23-10-2018 IPR006015 Universal stress protein A Mlab_0309 6a0f5b19be6354ca13e1161fa2979f00 142 Gene3D G3DSA:3.40.50.620 1 142 1.3E-37 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0309 6a0f5b19be6354ca13e1161fa2979f00 142 Pfam PF00582 Universal stress protein family 1 141 1.5E-32 T 23-10-2018 IPR006016 UspA Mlab_1078 9273acce93f155f03119d12492786de3 237 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 202 6.3E-46 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Mlab_1078 9273acce93f155f03119d12492786de3 237 Gene3D G3DSA:3.40.1010.10 1 109 1.1E-26 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Mlab_1078 9273acce93f155f03119d12492786de3 237 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 4 236 5.1E-78 T 23-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 Mlab_1078 9273acce93f155f03119d12492786de3 237 SUPERFAMILY SSF53790 4 224 1.01E-57 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Mlab_1078 9273acce93f155f03119d12492786de3 237 Gene3D G3DSA:3.30.950.10 110 224 9.1E-40 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Mlab_1078 9273acce93f155f03119d12492786de3 237 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 75 108 - T 23-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Mlab_1256 dfe2cb25f9541c80343da8b66bcd2f2f 563 Pfam PF13193 AMP-binding enzyme C-terminal domain 463 541 1.7E-21 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Mlab_1256 dfe2cb25f9541c80343da8b66bcd2f2f 563 Pfam PF00501 AMP-binding enzyme 35 454 1.1E-82 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Mlab_1256 dfe2cb25f9541c80343da8b66bcd2f2f 563 Gene3D G3DSA:3.30.300.30 450 561 2.3E-29 T 23-10-2018 Mlab_1256 dfe2cb25f9541c80343da8b66bcd2f2f 563 Gene3D G3DSA:3.40.50.12780 3 447 5.9E-139 T 23-10-2018 Mlab_1256 dfe2cb25f9541c80343da8b66bcd2f2f 563 SUPERFAMILY SSF56801 12 553 7.33E-150 T 23-10-2018 Mlab_1571 caa7abe46cf10ad435e7679bd85ece21 258 SMART SM00650 15 181 4.7E-71 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 Mlab_1571 caa7abe46cf10ad435e7679bd85ece21 258 Pfam PF00398 Ribosomal RNA adenine dimethylase 6 226 3.2E-48 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm Mlab_1571 caa7abe46cf10ad435e7679bd85ece21 258 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 7 254 4.4E-71 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Mlab_1571 caa7abe46cf10ad435e7679bd85ece21 258 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 1 255 43.015 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Mlab_1571 caa7abe46cf10ad435e7679bd85ece21 258 Gene3D G3DSA:3.40.50.150 2 182 1.6E-56 T 23-10-2018 Mlab_1571 caa7abe46cf10ad435e7679bd85ece21 258 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 30 57 - T 23-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 Mlab_1571 caa7abe46cf10ad435e7679bd85ece21 258 Gene3D G3DSA:1.10.8.100 190 253 3.0E-9 T 23-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 Mlab_1571 caa7abe46cf10ad435e7679bd85ece21 258 SUPERFAMILY SSF53335 5 256 2.09E-63 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0544 750ddffb997404b2383ca2ab9c199402 424 Gene3D G3DSA:3.90.1150.10 287 422 1.9E-45 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_0544 750ddffb997404b2383ca2ab9c199402 424 Gene3D G3DSA:3.40.640.10 6 286 7.3E-97 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_0544 750ddffb997404b2383ca2ab9c199402 424 SUPERFAMILY SSF53383 6 421 6.25E-119 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_0544 750ddffb997404b2383ca2ab9c199402 424 PIRSF PIRSF001434 2 424 2.6E-118 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Mlab_0544 750ddffb997404b2383ca2ab9c199402 424 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 7 421 4.9E-172 T 23-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 Mlab_0544 750ddffb997404b2383ca2ab9c199402 424 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 421 1.3E-128 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 Gene3D G3DSA:3.40.50.620 11 652 3.4E-259 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 SUPERFAMILY SSF47323 677 834 5.61E-24 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 Gene3D G3DSA:3.90.740.10 200 428 3.4E-259 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 Gene3D G3DSA:3.30.2320.20 792 932 4.9E-34 T 23-10-2018 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 382 496 2.5E-6 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 25 322 1.7E-40 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 SUPERFAMILY SSF50677 210 411 1.83E-32 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 51 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 Pfam PF09334 tRNA synthetases class I (M) 570 658 4.0E-6 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 7 932 15.5 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 9 932 0.0 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 SUPERFAMILY SSF52374 21 661 6.31E-88 T 23-10-2018 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 Gene3D G3DSA:1.10.730.10 655 767 1.7E-16 T 23-10-2018 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 Pfam PF08264 Anticodon-binding domain of tRNA 685 812 4.9E-18 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Mlab_1404 0c8b87f2d915d3eb770eeaeaed85d7e7 932 Gene3D G3DSA:1.10.10.720 822 880 4.9E-34 T 23-10-2018 Mlab_1637 c61a9998bde0603896a28618c07dd5ba 295 Pfam PF01798 snoRNA binding domain, fibrillarin 139 287 3.7E-35 T 23-10-2018 IPR002687 Nop domain Mlab_1637 c61a9998bde0603896a28618c07dd5ba 295 Gene3D G3DSA:1.10.246.90 179 292 3.2E-35 T 23-10-2018 Mlab_1637 c61a9998bde0603896a28618c07dd5ba 295 Gene3D G3DSA:1.10.287.660 88 177 2.0E-5 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily Mlab_1637 c61a9998bde0603896a28618c07dd5ba 295 SUPERFAMILY SSF89124 87 289 1.83E-49 T 23-10-2018 IPR036070 Nop domain superfamily Mlab_0035 28f002a7b363dbc3834b50aabac11af8 159 Gene3D G3DSA:2.30.110.10 6 157 1.1E-22 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Mlab_0035 28f002a7b363dbc3834b50aabac11af8 159 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 12 121 1.1E-22 T 23-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related Mlab_0035 28f002a7b363dbc3834b50aabac11af8 159 SUPERFAMILY SSF50475 6 147 1.38E-25 T 23-10-2018 Mlab_0954 05f29dc8f06cdb43332326684ef17d23 115 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 112 6.7E-28 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like Mlab_0511 41dc077390904231bb79c9c9e622b75f 903 PIRSF PIRSF037307 1 903 3.1E-285 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 Mlab_0511 41dc077390904231bb79c9c9e622b75f 903 Pfam PF00270 DEAD/DEAH box helicase 30 196 5.0E-29 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Mlab_0511 41dc077390904231bb79c9c9e622b75f 903 Gene3D G3DSA:3.40.50.300 225 378 1.3E-23 T 23-10-2018 Mlab_0511 41dc077390904231bb79c9c9e622b75f 903 Pfam PF00271 Helicase conserved C-terminal domain 245 338 4.7E-16 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0511 41dc077390904231bb79c9c9e622b75f 903 Pfam PF08494 DEAD/H associated 578 740 1.3E-24 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 Mlab_0511 41dc077390904231bb79c9c9e622b75f 903 SMART SM00487 24 227 6.2E-39 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Mlab_0511 41dc077390904231bb79c9c9e622b75f 903 SUPERFAMILY SSF52540 37 343 1.33E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0511 41dc077390904231bb79c9c9e622b75f 903 Gene3D G3DSA:3.40.50.300 10 213 1.5E-49 T 23-10-2018 Mlab_0511 41dc077390904231bb79c9c9e622b75f 903 SMART SM00490 257 338 6.2E-15 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0048 b204e12042cf8ced6d4452de7f97496c 176 Gene3D G3DSA:3.40.920.10 1 176 5.1E-52 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Mlab_0048 b204e12042cf8ced6d4452de7f97496c 176 SUPERFAMILY SSF53323 1 174 1.96E-40 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Mlab_0048 b204e12042cf8ced6d4452de7f97496c 176 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 172 6.0E-33 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Mlab_0048 b204e12042cf8ced6d4452de7f97496c 176 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 174 5.5E-53 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 Mlab_0122 6c9b55e7886b303659dc7b76232221d6 255 Gene3D G3DSA:1.20.120.1220 18 241 3.5E-10 T 23-10-2018 Mlab_0122 6c9b55e7886b303659dc7b76232221d6 255 Pfam PF06847 Archaeal Peptidase A24 C-terminus Type II 142 241 4.8E-19 T 23-10-2018 IPR009655 Preflagellin peptidase, C-terminal Mlab_0122 6c9b55e7886b303659dc7b76232221d6 255 Gene3D G3DSA:3.30.1360.160 124 227 3.5E-10 T 23-10-2018 Mlab_1120 60601bcfc1806fd0cb94d35d9254f624 292 SUPERFAMILY SSF48150 21 204 2.36E-46 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Mlab_1120 60601bcfc1806fd0cb94d35d9254f624 292 SMART SM00478 56 203 7.9E-26 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Mlab_1120 60601bcfc1806fd0cb94d35d9254f624 292 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 52 171 2.4E-13 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Mlab_1120 60601bcfc1806fd0cb94d35d9254f624 292 Gene3D G3DSA:1.10.1670.10 26 211 6.0E-53 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 Mlab_1120 60601bcfc1806fd0cb94d35d9254f624 292 Gene3D G3DSA:1.10.340.30 38 149 6.0E-53 T 23-10-2018 Mlab_0387 dee19177a08095ea0ed1b4f942ac79ac 186 Pfam PF04010 Protein of unknown function (DUF357) 104 175 4.3E-23 T 23-10-2018 IPR023140 Domain of unknown function DUF357 Mlab_0387 dee19177a08095ea0ed1b4f942ac79ac 186 Pfam PF04010 Protein of unknown function (DUF357) 19 75 9.6E-22 T 23-10-2018 IPR023140 Domain of unknown function DUF357 Mlab_0387 dee19177a08095ea0ed1b4f942ac79ac 186 SUPERFAMILY SSF158372 25 76 3.14E-17 T 23-10-2018 IPR036809 AF1782-like superfamily Mlab_0387 dee19177a08095ea0ed1b4f942ac79ac 186 Gene3D G3DSA:1.20.1270.90 3 78 7.0E-17 T 23-10-2018 Mlab_0387 dee19177a08095ea0ed1b4f942ac79ac 186 Gene3D G3DSA:1.20.1270.90 96 174 2.8E-8 T 23-10-2018 Mlab_0387 dee19177a08095ea0ed1b4f942ac79ac 186 SUPERFAMILY SSF158372 96 177 6.41E-16 T 23-10-2018 IPR036809 AF1782-like superfamily Mlab_1162 37e3af1d135619a99a244199b1290df5 637 Pfam PF04567 RNA polymerase Rpb2, domain 5 90 130 5.5E-7 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1162 37e3af1d135619a99a244199b1290df5 637 ProSitePatterns PS01166 RNA polymerases beta chain signature. 362 374 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1162 37e3af1d135619a99a244199b1290df5 637 Pfam PF00562 RNA polymerase Rpb2, domain 6 138 540 5.8E-132 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1162 37e3af1d135619a99a244199b1290df5 637 Gene3D G3DSA:3.90.1800.10 527 635 8.2E-41 T 23-10-2018 Mlab_1162 37e3af1d135619a99a244199b1290df5 637 Gene3D G3DSA:3.90.1070.20 1 57 5.4E-14 T 23-10-2018 Mlab_1162 37e3af1d135619a99a244199b1290df5 637 SUPERFAMILY SSF64484 4 635 2.66E-224 T 23-10-2018 Mlab_1162 37e3af1d135619a99a244199b1290df5 637 Pfam PF04566 RNA polymerase Rpb2, domain 4 8 69 5.9E-20 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1162 37e3af1d135619a99a244199b1290df5 637 Pfam PF04560 RNA polymerase Rpb2, domain 7 542 632 1.9E-30 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Mlab_1453 2a33b14a81a0b79547de83eec6ac2a50 427 PIRSF PIRSF037137 1 427 3.8E-181 T 23-10-2018 IPR017120 Bifunctional 3-hexulose-6-phosphate synthase/demethylmenaquinone methyltransferase, predicted KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 Mlab_1453 2a33b14a81a0b79547de83eec6ac2a50 427 SUPERFAMILY SSF51366 3 211 3.24E-36 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_1453 2a33b14a81a0b79547de83eec6ac2a50 427 SMART SM00934 5 205 5.4E-38 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_1453 2a33b14a81a0b79547de83eec6ac2a50 427 Pfam PF03737 Aldolase/RraA 236 382 8.8E-40 T 23-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein Mlab_1453 2a33b14a81a0b79547de83eec6ac2a50 427 SUPERFAMILY SSF89562 232 393 5.49E-43 T 23-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily Mlab_1453 2a33b14a81a0b79547de83eec6ac2a50 427 Gene3D G3DSA:3.20.20.70 1 212 1.1E-65 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1453 2a33b14a81a0b79547de83eec6ac2a50 427 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 204 7.8E-18 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Mlab_1453 2a33b14a81a0b79547de83eec6ac2a50 427 Gene3D G3DSA:3.50.30.40 232 392 1.5E-43 T 23-10-2018 Mlab_0972 0b9aa1194b91222531e289c9bc0a3663 183 Gene3D G3DSA:3.40.220.10 3 178 2.9E-73 T 23-10-2018 Mlab_0972 0b9aa1194b91222531e289c9bc0a3663 183 SUPERFAMILY SSF52949 8 170 6.06E-61 T 23-10-2018 Mlab_0972 0b9aa1194b91222531e289c9bc0a3663 183 Pfam PF01661 Macro domain 28 139 1.3E-41 T 23-10-2018 IPR002589 Macro domain Mlab_0972 0b9aa1194b91222531e289c9bc0a3663 183 SMART SM00506 11 140 8.5E-42 T 23-10-2018 IPR002589 Macro domain Mlab_0559 e8a7220a0f9cc44fb1456459dc82a4a8 277 SUPERFAMILY SSF53474 43 270 3.27E-45 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold Mlab_0559 e8a7220a0f9cc44fb1456459dc82a4a8 277 Gene3D G3DSA:3.40.50.1820 42 271 2.9E-42 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold Mlab_0559 e8a7220a0f9cc44fb1456459dc82a4a8 277 Pfam PF12146 Serine aminopeptidase, S33 84 169 3.9E-16 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 Mlab_1663 789324ee0abc3991edd8b23cca44947e 275 Gene3D G3DSA:3.90.1170.20 10 271 2.7E-83 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 Mlab_1663 789324ee0abc3991edd8b23cca44947e 275 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 107 272 7.5E-47 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 Mlab_1663 789324ee0abc3991edd8b23cca44947e 275 SUPERFAMILY SSF54675 4 102 3.3E-23 T 23-10-2018 Mlab_1663 789324ee0abc3991edd8b23cca44947e 275 SUPERFAMILY SSF51690 103 272 2.67E-45 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 Mlab_1663 789324ee0abc3991edd8b23cca44947e 275 PIRSF PIRSF006250 3 275 2.6E-79 T 23-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 Mlab_1663 789324ee0abc3991edd8b23cca44947e 275 Gene3D G3DSA:3.20.20.70 119 263 2.7E-83 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1663 789324ee0abc3991edd8b23cca44947e 275 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 101 8.2E-24 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 Mlab_1663 789324ee0abc3991edd8b23cca44947e 275 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 7 273 1.8E-80 T 23-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 Mlab_0132 b3c10b2a9b879c9a01d73ae998f54ea1 176 PIRSF PIRSF016661 3 175 1.2E-32 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 Mlab_0132 b3c10b2a9b879c9a01d73ae998f54ea1 176 Pfam PF02632 BioY family 32 168 8.1E-34 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 Mlab_0132 b3c10b2a9b879c9a01d73ae998f54ea1 176 Gene3D G3DSA:1.10.1760.20 2 175 5.0E-44 T 23-10-2018 Mlab_0109 2c3d1f53127a2561328511f0de678f68 239 SUPERFAMILY SSF55831 16 204 1.57E-40 T 23-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Mlab_0109 2c3d1f53127a2561328511f0de678f68 239 TIGRFAM TIGR03283 thy_syn_methano: thymidylate synthase, methanogen type 3 209 7.5E-63 T 23-10-2018 IPR014620 Thymidylate synthase, archaea GO:0004799|GO:0005737|GO:0006235 Mlab_0109 2c3d1f53127a2561328511f0de678f68 239 Hamap MF_01686 Putative thymidylate synthase [thyA]. 1 239 114.24 T 23-10-2018 IPR014620 Thymidylate synthase, archaea GO:0004799|GO:0005737|GO:0006235 Mlab_0109 2c3d1f53127a2561328511f0de678f68 239 Gene3D G3DSA:3.30.572.10 47 210 7.1E-29 T 23-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Mlab_0109 2c3d1f53127a2561328511f0de678f68 239 PIRSF PIRSF036752 1 217 8.0E-55 T 23-10-2018 IPR014620 Thymidylate synthase, archaea GO:0004799|GO:0005737|GO:0006235 Mlab_0109 2c3d1f53127a2561328511f0de678f68 239 Pfam PF00303 Thymidylate synthase 100 205 1.1E-16 T 23-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 SUPERFAMILY SSF55945 98 182 1.49E-24 T 23-10-2018 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 PRINTS PR00686 Transcription initiation factor TFIID signature 11 26 3.8E-35 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 PRINTS PR00686 Transcription initiation factor TFIID signature 35 54 3.8E-35 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 PRINTS PR00686 Transcription initiation factor TFIID signature 127 142 3.8E-35 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 PRINTS PR00686 Transcription initiation factor TFIID signature 102 118 3.8E-35 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 PRINTS PR00686 Transcription initiation factor TFIID signature 146 162 3.8E-35 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 PRINTS PR00686 Transcription initiation factor TFIID signature 54 72 3.8E-35 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 SUPERFAMILY SSF55945 6 94 6.12E-20 T 23-10-2018 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 131 180 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 Hamap MF_00408 TATA-box-binding protein [tbp]. 5 186 31.847 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 100 181 2.9E-23 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 9 89 5.1E-21 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 Gene3D G3DSA:3.30.310.10 16 102 1.8E-51 T 23-10-2018 IPR012295 TBP domain superfamily Mlab_0440 a3df0d1521351e8848cade4e22efee35 188 Gene3D G3DSA:3.30.310.10 11 173 1.8E-51 T 23-10-2018 IPR012295 TBP domain superfamily Mlab_0684 5ac0c37ff08e82f770deaae7035bcdbd 447 Pfam PF00753 Metallo-beta-lactamase superfamily 74 108 3.5E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0684 5ac0c37ff08e82f770deaae7035bcdbd 447 Gene3D G3DSA:3.40.50.10710 218 379 2.9E-128 T 23-10-2018 Mlab_0684 5ac0c37ff08e82f770deaae7035bcdbd 447 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 381 436 1.9E-8 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain Mlab_0684 5ac0c37ff08e82f770deaae7035bcdbd 447 Hamap MF_01492 Ribonuclease J [rnj]. 3 446 54.281 T 23-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 Mlab_0684 5ac0c37ff08e82f770deaae7035bcdbd 447 SUPERFAMILY SSF56281 4 443 4.06E-63 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_0684 5ac0c37ff08e82f770deaae7035bcdbd 447 SMART SM00849 16 230 5.6E-20 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0684 5ac0c37ff08e82f770deaae7035bcdbd 447 Gene3D G3DSA:3.60.15.10 7 444 2.9E-128 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_0684 5ac0c37ff08e82f770deaae7035bcdbd 447 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 4 445 8.9E-135 T 23-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 Mlab_1623 7dd99e22c2cbd30d93dfad9a274c409a 289 Pfam PF00146 NADH dehydrogenase 11 280 1.0E-32 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_1628 73a06f642a23787c8d2b71702bda380f 236 PIRSF PIRSF037724 1 236 5.4E-91 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted Mlab_1628 73a06f642a23787c8d2b71702bda380f 236 Gene3D G3DSA:1.10.260.40 13 81 5.2E-6 T 23-10-2018 Mlab_1628 73a06f642a23787c8d2b71702bda380f 236 SMART SM00530 26 81 1.1E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_1628 73a06f642a23787c8d2b71702bda380f 236 SUPERFAMILY SSF47413 23 74 2.95E-7 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Mlab_0828 9d4b3e63d6c3b81531b552d6ee03ab80 455 Gene3D G3DSA:3.40.605.10 3 447 5.1E-156 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Mlab_0828 9d4b3e63d6c3b81531b552d6ee03ab80 455 SUPERFAMILY SSF53720 4 454 1.13E-144 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Mlab_0828 9d4b3e63d6c3b81531b552d6ee03ab80 455 Pfam PF00171 Aldehyde dehydrogenase family 4 452 4.8E-148 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Mlab_0828 9d4b3e63d6c3b81531b552d6ee03ab80 455 Gene3D G3DSA:3.40.309.10 237 424 5.1E-156 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Mlab_1150 2e937625ee08044ad7d2a884a564da86 338 Pfam PF04055 Radical SAM superfamily 80 234 9.3E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_1150 2e937625ee08044ad7d2a884a564da86 338 SUPERFAMILY SSF102114 55 310 2.49E-37 T 23-10-2018 Mlab_1150 2e937625ee08044ad7d2a884a564da86 338 SMART SM00729 73 272 0.0039 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_1150 2e937625ee08044ad7d2a884a564da86 338 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 9 334 3.2E-102 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme Mlab_1150 2e937625ee08044ad7d2a884a564da86 338 PIRSF PIRSF004869 2 310 4.7E-95 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted Mlab_1150 2e937625ee08044ad7d2a884a564da86 338 Gene3D G3DSA:3.20.20.70 66 281 2.0E-33 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1456 ca93f437a2b76c6fcdc17f1ec4264758 433 Pfam PF00501 AMP-binding enzyme 74 285 5.2E-17 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Mlab_1456 ca93f437a2b76c6fcdc17f1ec4264758 433 Pfam PF14535 AMP-binding enzyme C-terminal domain 335 431 2.7E-26 T 23-10-2018 IPR028154 AMP-dependent ligase, C-terminal Mlab_1456 ca93f437a2b76c6fcdc17f1ec4264758 433 Gene3D G3DSA:3.30.300.30 327 432 6.4E-30 T 23-10-2018 Mlab_1456 ca93f437a2b76c6fcdc17f1ec4264758 433 Gene3D G3DSA:3.40.50.12780 1 326 7.9E-116 T 23-10-2018 Mlab_1456 ca93f437a2b76c6fcdc17f1ec4264758 433 SUPERFAMILY SSF56801 47 382 9.55E-54 T 23-10-2018 Mlab_1456 ca93f437a2b76c6fcdc17f1ec4264758 433 PIRSF PIRSF006444 1 433 1.8E-198 T 23-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 Mlab_1427 9c9dea039694e23b36dc36aed94dab04 375 TIGRFAM TIGR04440 glyco_TIGR04440: glycosyltransferase domain 22 235 5.4E-65 T 23-10-2018 IPR031042 Glycosyltransferase domain Mlab_1427 9c9dea039694e23b36dc36aed94dab04 375 SUPERFAMILY SSF53448 21 187 6.56E-10 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1576 688d670d4702e118ae0e8f597046b832 266 SUPERFAMILY SSF46785 3 109 5.17E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1576 688d670d4702e118ae0e8f597046b832 266 Pfam PF13412 Winged helix-turn-helix DNA-binding 16 61 8.8E-10 T 23-10-2018 Mlab_1576 688d670d4702e118ae0e8f597046b832 266 SMART SM00419 24 73 1.7E-10 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Mlab_1576 688d670d4702e118ae0e8f597046b832 266 PIRSF PIRSF004955 6 266 3.9E-88 T 23-10-2018 IPR012015 Uncharacterised conserved protein HTH transcriptional regulator, archaea Mlab_1576 688d670d4702e118ae0e8f597046b832 266 Gene3D G3DSA:1.10.10.10 10 103 1.1E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0824 012573a2594669a8fc531e11f8a19190 251 Pfam PF01022 Bacterial regulatory protein, arsR family 178 219 1.5E-4 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0824 012573a2594669a8fc531e11f8a19190 251 SUPERFAMILY SSF46785 164 248 1.51E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0824 012573a2594669a8fc531e11f8a19190 251 PIRSF PIRSF018357 1 251 1.5E-85 T 23-10-2018 IPR016723 Transcription regulator, ArsR, predicted Mlab_0824 012573a2594669a8fc531e11f8a19190 251 Gene3D G3DSA:1.10.10.10 148 241 8.9E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1182 e4be939ef09496a1a08d8e5ee925fd34 362 Pfam PF00072 Response regulator receiver domain 3 83 5.4E-7 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Mlab_1182 e4be939ef09496a1a08d8e5ee925fd34 362 Gene3D G3DSA:3.40.50.2300 1 115 2.2E-10 T 23-10-2018 Mlab_1182 e4be939ef09496a1a08d8e5ee925fd34 362 SUPERFAMILY SSF52172 1 86 1.57E-11 T 23-10-2018 IPR011006 CheY-like superfamily Mlab_0479 92a0cdf6586415efbda20d095ac9ed39 132 Pfam PF02391 MoaE protein 5 113 5.0E-29 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Mlab_0479 92a0cdf6586415efbda20d095ac9ed39 132 Gene3D G3DSA:3.90.1170.40 1 132 1.0E-37 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Mlab_0479 92a0cdf6586415efbda20d095ac9ed39 132 SUPERFAMILY SSF54690 4 131 2.88E-36 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Mlab_1682 6d87a446c1f342ce8cfb55cb83ae54e8 847 Pfam PF00069 Protein kinase domain 14 169 2.5E-14 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Mlab_1682 6d87a446c1f342ce8cfb55cb83ae54e8 847 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 51 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 Mlab_1682 6d87a446c1f342ce8cfb55cb83ae54e8 847 SUPERFAMILY SSF52540 286 400 1.62E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1682 6d87a446c1f342ce8cfb55cb83ae54e8 847 SMART SM00220 14 257 1.6E-7 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Mlab_1682 6d87a446c1f342ce8cfb55cb83ae54e8 847 Gene3D G3DSA:1.10.510.10 2 185 8.1E-18 T 23-10-2018 Mlab_1682 6d87a446c1f342ce8cfb55cb83ae54e8 847 SUPERFAMILY SSF56112 13 220 3.6E-23 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily Mlab_0724 e27b65b110c5ee2f6caa5656fa947922 406 Gene3D G3DSA:1.20.1250.20 12 400 6.4E-44 T 23-10-2018 Mlab_0724 e27b65b110c5ee2f6caa5656fa947922 406 Pfam PF07690 Major Facilitator Superfamily 252 398 2.5E-12 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_0724 e27b65b110c5ee2f6caa5656fa947922 406 Pfam PF07690 Major Facilitator Superfamily 27 246 2.0E-24 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_0724 e27b65b110c5ee2f6caa5656fa947922 406 ProSitePatterns PS00216 Sugar transport proteins signature 1. 276 292 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Mlab_0724 e27b65b110c5ee2f6caa5656fa947922 406 SUPERFAMILY SSF103473 21 399 3.27E-53 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_0654 ef5390e372de57006df957aa2e78785e 60 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 13 59 16.029 T 23-10-2018 IPR022845 Ribosomal protein S27ae Mlab_0654 ef5390e372de57006df957aa2e78785e 60 Pfam PF01599 Ribosomal protein S27a 15 56 1.8E-19 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 Mlab_0654 ef5390e372de57006df957aa2e78785e 60 Gene3D G3DSA:2.20.25.660 2 59 2.0E-20 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 Mlab_0654 ef5390e372de57006df957aa2e78785e 60 SMART SM01402 13 56 1.4E-21 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 Mlab_0654 ef5390e372de57006df957aa2e78785e 60 SUPERFAMILY SSF57829 14 60 1.25E-17 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Mlab_1365 405d8cd07bd229c75990d86ecf14dea0 312 SMART SM00849 23 214 0.0013 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1365 405d8cd07bd229c75990d86ecf14dea0 312 SUPERFAMILY SSF56281 8 307 1.36E-74 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1365 405d8cd07bd229c75990d86ecf14dea0 312 Gene3D G3DSA:3.60.15.10 6 307 2.2E-85 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1365 405d8cd07bd229c75990d86ecf14dea0 312 Pfam PF00753 Metallo-beta-lactamase superfamily 21 225 3.9E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1365 405d8cd07bd229c75990d86ecf14dea0 312 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 8 306 5.8E-89 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 Mlab_1365 405d8cd07bd229c75990d86ecf14dea0 312 Hamap MF_01818 Ribonuclease BN [rbn]. 6 307 33.581 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 Mlab_0171 31b476e5db27717bb3e61e7797e05c69 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 324 5.9E-39 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_0171 31b476e5db27717bb3e61e7797e05c69 333 SUPERFAMILY SSF161098 101 307 4.71E-18 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0171 31b476e5db27717bb3e61e7797e05c69 333 Gene3D G3DSA:1.10.3720.10 95 319 1.4E-20 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_1360 f9f1410ee8659e050bdab6e5d6ff751d 82 Gene3D G3DSA:3.90.820.10 7 74 6.5E-12 T 23-10-2018 Mlab_1360 f9f1410ee8659e050bdab6e5d6ff751d 82 Pfam PF09082 Domain of unknown function (DUF1922) 12 65 2.0E-10 T 23-10-2018 IPR015166 Protein of unknown function DUF1922 Mlab_1360 f9f1410ee8659e050bdab6e5d6ff751d 82 SUPERFAMILY SSF57821 14 72 2.09E-8 T 23-10-2018 IPR036304 Hypothetical protein MTH1184 Mlab_0517 1e2a917db7afc1cb96cf0241fb5d7892 124 SMART SM00567 E-Z type HEAT repeats 17 45 13.0 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Mlab_0517 1e2a917db7afc1cb96cf0241fb5d7892 124 SMART SM00567 E-Z type HEAT repeats 47 76 0.11 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Mlab_0517 1e2a917db7afc1cb96cf0241fb5d7892 124 SMART SM00567 E-Z type HEAT repeats 78 107 4.1 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Mlab_0517 1e2a917db7afc1cb96cf0241fb5d7892 124 SUPERFAMILY SSF48371 4 121 2.16E-24 T 23-10-2018 IPR016024 Armadillo-type fold Mlab_0517 1e2a917db7afc1cb96cf0241fb5d7892 124 Pfam PF13646 HEAT repeats 37 115 2.8E-15 T 23-10-2018 Mlab_0517 1e2a917db7afc1cb96cf0241fb5d7892 124 Gene3D G3DSA:1.25.10.10 3 123 2.9E-23 T 23-10-2018 IPR011989 Armadillo-like helical Mlab_0237 c6546176dc70100dcb8c5d9ec325d5c1 93 SUPERFAMILY SSF54862 4 81 3.0E-19 T 23-10-2018 Mlab_0237 c6546176dc70100dcb8c5d9ec325d5c1 93 Pfam PF12838 4Fe-4S dicluster domain 11 72 4.0E-13 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0237 c6546176dc70100dcb8c5d9ec325d5c1 93 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 12 23 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0237 c6546176dc70100dcb8c5d9ec325d5c1 93 Gene3D G3DSA:3.30.70.20 33 77 2.3E-8 T 23-10-2018 Mlab_0237 c6546176dc70100dcb8c5d9ec325d5c1 93 Gene3D G3DSA:3.30.70.20 2 32 2.4E-7 T 23-10-2018 Mlab_0237 c6546176dc70100dcb8c5d9ec325d5c1 93 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 58 69 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0672 15c23916d4390f354d4b9707cdce3ab4 297 Gene3D G3DSA:3.30.420.10 142 268 9.9E-7 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Mlab_0672 15c23916d4390f354d4b9707cdce3ab4 297 Pfam PF13482 RNase_H superfamily 143 239 8.5E-18 T 23-10-2018 IPR038720 YprB, ribonuclease H-like domain Mlab_0672 15c23916d4390f354d4b9707cdce3ab4 297 SUPERFAMILY SSF53098 138 241 3.94E-17 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily Mlab_1498 a8903c02efedf608cf4b9a6df390de23 69 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1498 a8903c02efedf608cf4b9a6df390de23 69 Pfam PF01200 Ribosomal protein S28e 4 66 3.2E-30 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1498 a8903c02efedf608cf4b9a6df390de23 69 SUPERFAMILY SSF50249 3 67 4.71E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_1498 a8903c02efedf608cf4b9a6df390de23 69 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 23.845 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1498 a8903c02efedf608cf4b9a6df390de23 69 Gene3D G3DSA:2.40.50.140 2 68 2.2E-30 T 23-10-2018 Mlab_1498 a8903c02efedf608cf4b9a6df390de23 69 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 4 47 1.0E-14 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1334 61f38d9d75db6ea6689db096acd41dc5 198 SUPERFAMILY SSF52540 2 192 1.9E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1334 61f38d9d75db6ea6689db096acd41dc5 198 Gene3D G3DSA:3.40.50.300 1 194 1.4E-46 T 23-10-2018 Mlab_1334 61f38d9d75db6ea6689db096acd41dc5 198 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 186 1.1E-38 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Mlab_1334 61f38d9d75db6ea6689db096acd41dc5 198 Hamap MF_00165 Thymidylate kinase [tmk]. 1 196 22.615 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Mlab_1334 61f38d9d75db6ea6689db096acd41dc5 198 Pfam PF02223 Thymidylate kinase 5 184 1.3E-35 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 Mlab_0540 5fee484603b348efd1078c255b67bce4 642 Pfam PF05670 Domain of unknown function (DUF814) 437 530 3.2E-21 T 23-10-2018 IPR008532 Domain of unknown function DUF814 Mlab_0540 5fee484603b348efd1078c255b67bce4 642 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 9 411 2.1E-55 T 23-10-2018 Mlab_0540 5fee484603b348efd1078c255b67bce4 642 Gene3D G3DSA:2.30.310.10 6 157 1.3E-25 T 23-10-2018 Mlab_1306 8e6775c734ebbff8480f8a65a412cbcb 279 Gene3D G3DSA:1.10.4080.10 1 274 5.5E-59 T 23-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily Mlab_1306 8e6775c734ebbff8480f8a65a412cbcb 279 Pfam PF03747 ADP-ribosylglycohydrolase 10 185 1.9E-29 T 23-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 Mlab_1306 8e6775c734ebbff8480f8a65a412cbcb 279 Pfam PF03747 ADP-ribosylglycohydrolase 202 248 7.0E-10 T 23-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 Mlab_1306 8e6775c734ebbff8480f8a65a412cbcb 279 SUPERFAMILY SSF101478 1 272 7.06E-50 T 23-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily Mlab_0523 fe2f14498066ffe30c59b720eb525112 424 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 162 302 9.8E-35 T 23-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase Mlab_0523 fe2f14498066ffe30c59b720eb525112 424 Gene3D G3DSA:3.40.50.720 151 309 1.6E-43 T 23-10-2018 Mlab_0523 fe2f14498066ffe30c59b720eb525112 424 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 15 146 1.4E-22 T 23-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Mlab_0523 fe2f14498066ffe30c59b720eb525112 424 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 30 404 1.8E-90 T 23-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Mlab_0523 fe2f14498066ffe30c59b720eb525112 424 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 317 408 2.0E-10 T 23-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Mlab_0523 fe2f14498066ffe30c59b720eb525112 424 SUPERFAMILY SSF51735 150 311 2.14E-32 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0523 fe2f14498066ffe30c59b720eb525112 424 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 8 412 22.9 T 23-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Mlab_0523 fe2f14498066ffe30c59b720eb525112 424 SUPERFAMILY SSF69075 314 408 7.06E-12 T 23-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Mlab_0523 fe2f14498066ffe30c59b720eb525112 424 SUPERFAMILY SSF69742 8 148 1.29E-27 T 23-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Mlab_0523 fe2f14498066ffe30c59b720eb525112 424 Gene3D G3DSA:3.30.460.30 6 150 2.5E-25 T 23-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Mlab_0523 fe2f14498066ffe30c59b720eb525112 424 PIRSF PIRSF000445 7 418 1.0E-102 T 23-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Mlab_0735 efa74ec9ea911aac7ff952b2a55e6b5a 612 SUPERFAMILY SSF64182 221 607 8.76E-39 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily Mlab_0735 efa74ec9ea911aac7ff952b2a55e6b5a 612 SUPERFAMILY SSF50249 110 183 4.97E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_0735 efa74ec9ea911aac7ff952b2a55e6b5a 612 Pfam PF01336 OB-fold nucleic acid binding domain 112 184 2.8E-6 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Mlab_0735 efa74ec9ea911aac7ff952b2a55e6b5a 612 Gene3D G3DSA:2.40.50.140 104 189 3.1E-6 T 23-10-2018 Mlab_0735 efa74ec9ea911aac7ff952b2a55e6b5a 612 Gene3D G3DSA:3.90.1640.30 216 409 2.2E-11 T 23-10-2018 Mlab_0735 efa74ec9ea911aac7ff952b2a55e6b5a 612 Gene3D G3DSA:2.40.50.140 18 70 4.3E-6 T 23-10-2018 Mlab_0735 efa74ec9ea911aac7ff952b2a55e6b5a 612 SMART SM00316 18 80 1.3E-4 T 23-10-2018 IPR022967 RNA-binding domain, S1 Mlab_0735 efa74ec9ea911aac7ff952b2a55e6b5a 612 SUPERFAMILY SSF50249 16 77 3.15E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_1039 9a3ee4a8d86c0fa7ecc95d62e9439af5 387 Gene3D G3DSA:3.40.50.1980 143 253 4.2E-19 T 23-10-2018 Mlab_1039 9a3ee4a8d86c0fa7ecc95d62e9439af5 387 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 15 233 1.8E-29 T 23-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 Mlab_1039 9a3ee4a8d86c0fa7ecc95d62e9439af5 387 Gene3D G3DSA:3.40.50.1980 15 142 2.1E-21 T 23-10-2018 Mlab_1039 9a3ee4a8d86c0fa7ecc95d62e9439af5 387 SUPERFAMILY SSF53807 8 333 2.94E-50 T 23-10-2018 Mlab_0936 6c8b27b57a43dc2e1a5373ecec3b19ba 520 Hamap MF_00203 UvrABC system protein C [uvrC]. 1 520 21.773 T 23-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 Mlab_0936 6c8b27b57a43dc2e1a5373ecec3b19ba 520 SMART SM00465 12 93 3.6E-19 T 23-10-2018 IPR000305 GIY-YIG endonuclease Mlab_0936 6c8b27b57a43dc2e1a5373ecec3b19ba 520 Pfam PF02151 UvrB/uvrC motif 195 228 3.4E-7 T 23-10-2018 IPR001943 UVR domain GO:0005515 Mlab_0936 6c8b27b57a43dc2e1a5373ecec3b19ba 520 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 517 5.3E-151 T 23-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 Mlab_0936 6c8b27b57a43dc2e1a5373ecec3b19ba 520 Pfam PF01541 GIY-YIG catalytic domain 14 88 7.8E-12 T 23-10-2018 IPR000305 GIY-YIG endonuclease Mlab_0936 6c8b27b57a43dc2e1a5373ecec3b19ba 520 Gene3D G3DSA:3.40.1440.10 4 97 3.0E-32 T 23-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Mlab_0936 6c8b27b57a43dc2e1a5373ecec3b19ba 520 Gene3D G3DSA:3.30.420.340 352 517 1.6E-58 T 23-10-2018 IPR038476 UvrC homology region 2 superfamily Mlab_0936 6c8b27b57a43dc2e1a5373ecec3b19ba 520 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 359 507 3.8E-53 T 23-10-2018 IPR001162 UvrC family homology region Mlab_0936 6c8b27b57a43dc2e1a5373ecec3b19ba 520 SUPERFAMILY SSF46600 182 233 4.45E-10 T 23-10-2018 IPR036876 UVR domain superfamily Mlab_0936 6c8b27b57a43dc2e1a5373ecec3b19ba 520 SUPERFAMILY SSF82771 12 94 8.24E-23 T 23-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Mlab_1602 ae6750e208ffa283148b787ea08b0f24 206 Gene3D G3DSA:3.40.50.1010 29 112 4.6E-5 T 23-10-2018 Mlab_1602 ae6750e208ffa283148b787ea08b0f24 206 SUPERFAMILY SSF88723 60 117 1.09E-5 T 23-10-2018 IPR029060 PIN-like domain superfamily Mlab_0092 5b9a2f2000a80f5fd256c8038314b1e8 121 SUPERFAMILY SSF50104 6 116 5.12E-31 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily Mlab_0092 5b9a2f2000a80f5fd256c8038314b1e8 121 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 6 119 27.98 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0092 5b9a2f2000a80f5fd256c8038314b1e8 121 ProSitePatterns PS01108 Ribosomal protein L24 signature. 50 67 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0092 5b9a2f2000a80f5fd256c8038314b1e8 121 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 6 120 2.2E-26 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0092 5b9a2f2000a80f5fd256c8038314b1e8 121 Gene3D G3DSA:2.30.30.30 1 121 8.3E-39 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 Mlab_0092 5b9a2f2000a80f5fd256c8038314b1e8 121 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 1.1E-38 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0284 37423dba3bea5c4d75ac0929ad68953a 391 Gene3D G3DSA:1.20.1250.20 5 390 2.6E-49 T 23-10-2018 Mlab_0284 37423dba3bea5c4d75ac0929ad68953a 391 SUPERFAMILY SSF103473 1 390 6.67E-60 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_0284 37423dba3bea5c4d75ac0929ad68953a 391 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 82 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Mlab_0284 37423dba3bea5c4d75ac0929ad68953a 391 Pfam PF07690 Major Facilitator Superfamily 15 277 2.1E-28 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_0012 d68d0b253f673e1687e912c09c9f8c40 290 Gene3D G3DSA:2.30.30.1030 140 187 1.8E-15 T 23-10-2018 Mlab_0012 d68d0b253f673e1687e912c09c9f8c40 290 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 10 87 4.7E-29 T 23-10-2018 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal Mlab_0012 d68d0b253f673e1687e912c09c9f8c40 290 TIGRFAM TIGR03289 frhB: coenzyme F420 hydrogenase, subunit beta 4 275 5.1E-132 T 23-10-2018 IPR017679 Coenzyme F420 hydrogenase, subunit beta GO:0016151|GO:0050454|GO:0050660|GO:0051536|GO:0055114 KEGG: 00680+1.12.98.1|MetaCyc: PWY-5207 Mlab_0012 d68d0b253f673e1687e912c09c9f8c40 290 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 96 247 2.0E-42 T 23-10-2018 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal Mlab_0377 2888a76e1aaea8642f6d3c3b205b839f 253 Gene3D G3DSA:1.10.3720.10 51 244 1.1E-27 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0377 2888a76e1aaea8642f6d3c3b205b839f 253 SUPERFAMILY SSF161098 53 237 5.23E-33 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0377 2888a76e1aaea8642f6d3c3b205b839f 253 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 234 2.1E-23 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_1152 8ee98ee74f94bd8da166bd1f1d140451 255 SUPERFAMILY SSF52540 3 231 3.55E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1152 8ee98ee74f94bd8da166bd1f1d140451 255 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1152 8ee98ee74f94bd8da166bd1f1d140451 255 SMART SM00382 27 214 9.5E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1152 8ee98ee74f94bd8da166bd1f1d140451 255 Gene3D G3DSA:3.40.50.300 1 252 4.0E-71 T 23-10-2018 Mlab_1152 8ee98ee74f94bd8da166bd1f1d140451 255 Pfam PF00005 ABC transporter 18 165 1.0E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1514 7dbdbfb600cd8a1ece63f321a8b6d18d 90 Pfam PF01922 SRP19 protein 6 85 3.5E-18 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Mlab_1514 7dbdbfb600cd8a1ece63f321a8b6d18d 90 SUPERFAMILY SSF69695 4 87 1.07E-20 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Mlab_1514 7dbdbfb600cd8a1ece63f321a8b6d18d 90 Gene3D G3DSA:3.30.56.30 5 90 7.9E-24 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Mlab_1514 7dbdbfb600cd8a1ece63f321a8b6d18d 90 Hamap MF_00305 Signal recognition particle 19 kDa protein [srp19]. 5 89 25.697 T 23-10-2018 IPR022938 Signal recognition particle, SRP19 subunit, archaeal-type Mlab_0346 fbcebbc1e57b25a89a505f5e51cdefe4 286 Pfam PF09872 Uncharacterized protein conserved in archaea (DUF2099) 5 259 3.8E-100 T 23-10-2018 IPR009181 Uncharacterised conserved protein UCP004929, methanogenesis Mlab_0346 fbcebbc1e57b25a89a505f5e51cdefe4 286 TIGRFAM TIGR03275 methan_mark_8: putative methanogenesis marker protein 8 5 259 5.9E-92 T 23-10-2018 IPR009181 Uncharacterised conserved protein UCP004929, methanogenesis Mlab_0346 fbcebbc1e57b25a89a505f5e51cdefe4 286 PIRSF PIRSF004929 1 286 4.0E-97 T 23-10-2018 IPR009181 Uncharacterised conserved protein UCP004929, methanogenesis Mlab_0656 cd9ab1fcb16d4bb440dd9b769a908717 161 Hamap MF_00590 UPF0218 protein . 4 161 27.504 T 23-10-2018 IPR007164 Protein of unknown function DUF359 Mlab_0656 cd9ab1fcb16d4bb440dd9b769a908717 161 Pfam PF04019 Protein of unknown function (DUF359) 42 158 3.8E-35 T 23-10-2018 IPR007164 Protein of unknown function DUF359 Mlab_0656 cd9ab1fcb16d4bb440dd9b769a908717 161 PIRSF PIRSF006533 1 161 1.4E-40 T 23-10-2018 IPR007164 Protein of unknown function DUF359 Mlab_1214 0c0cba8a0e74576c8d65dffd6a133654 392 Pfam PF05889 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS 101 377 1.1E-20 T 23-10-2018 IPR008829 SepSecS/SepCysS family GO:0016740 Reactome: R-HSA-2408557 Mlab_1214 0c0cba8a0e74576c8d65dffd6a133654 392 Gene3D G3DSA:3.40.640.10 25 284 5.7E-129 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_1214 0c0cba8a0e74576c8d65dffd6a133654 392 Gene3D G3DSA:3.90.1150.10 13 385 5.7E-129 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_1214 0c0cba8a0e74576c8d65dffd6a133654 392 Hamap MF_01675 O-phospho-L-seryl-tRNA:Cys-tRNA synthase. 1 388 52.837 T 23-10-2018 IPR013375 O-phosphoseryl-tRNA:Cys-tRNA synthase, archaea GO:0043766 KEGG: 00970+2.5.1.73|MetaCyc: PWY-6308 Mlab_1214 0c0cba8a0e74576c8d65dffd6a133654 392 SUPERFAMILY SSF53383 6 382 3.13E-49 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_0466 b50fb8e749c45b84d2d4aa7ffe981421 235 Gene3D G3DSA:1.10.3720.10 5 230 2.0E-31 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0466 b50fb8e749c45b84d2d4aa7ffe981421 235 SUPERFAMILY SSF161098 16 219 1.44E-32 T 23-10-2018 IPR035906 MetI-like superfamily Mlab_0466 b50fb8e749c45b84d2d4aa7ffe981421 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 225 9.1E-11 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Mlab_0016 b2cb538cdccbbcc0ab18623ec8bba1cc 341 Pfam PF01969 Protein of unknown function DUF111 121 328 7.2E-48 T 23-10-2018 IPR002822 Nickel insertion protein Mlab_0016 b2cb538cdccbbcc0ab18623ec8bba1cc 341 Gene3D G3DSA:3.10.20.300 275 337 8.1E-6 T 23-10-2018 Mlab_0016 b2cb538cdccbbcc0ab18623ec8bba1cc 341 Gene3D G3DSA:3.30.70.1380 185 274 2.1E-20 T 23-10-2018 Mlab_0755 49e1f0bf0d8cc6e4f23091c7a3994976 209 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 7 209 32.98 T 23-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Mlab_0755 49e1f0bf0d8cc6e4f23091c7a3994976 209 Pfam PF01973 Protein of unknown function DUF115 35 184 1.1E-28 T 23-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like Mlab_0755 49e1f0bf0d8cc6e4f23091c7a3994976 209 SUPERFAMILY SSF63999 44 123 7.46E-8 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 Mlab_0755 49e1f0bf0d8cc6e4f23091c7a3994976 209 Gene3D G3DSA:3.40.50.10240 50 123 3.6E-5 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 Mlab_0212 6223bf6ff85be0c180730f8d01724f59 157 PIRSF PIRSF004749 1 157 2.0E-39 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0212 6223bf6ff85be0c180730f8d01724f59 157 SUPERFAMILY SSF56420 1 156 2.75E-44 T 23-10-2018 IPR036821 Peptide deformylase superfamily Mlab_0212 6223bf6ff85be0c180730f8d01724f59 157 Pfam PF01327 Polypeptide deformylase 4 148 4.6E-37 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0212 6223bf6ff85be0c180730f8d01724f59 157 Gene3D G3DSA:3.90.45.10 1 157 4.3E-39 T 23-10-2018 IPR036821 Peptide deformylase superfamily Mlab_0212 6223bf6ff85be0c180730f8d01724f59 157 Hamap MF_00163 Peptide deformylase [def]. 1 155 20.285 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0212 6223bf6ff85be0c180730f8d01724f59 157 PRINTS PR01576 Peptide deformylase signature 85 96 5.2E-24 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0212 6223bf6ff85be0c180730f8d01724f59 157 PRINTS PR01576 Peptide deformylase signature 116 145 5.2E-24 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0212 6223bf6ff85be0c180730f8d01724f59 157 PRINTS PR01576 Peptide deformylase signature 32 61 5.2E-24 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0212 6223bf6ff85be0c180730f8d01724f59 157 PRINTS PR01576 Peptide deformylase signature 97 115 5.2E-24 T 23-10-2018 IPR023635 Peptide deformylase Mlab_0034 c9269b434371e53d2f9d300679febc91 297 Gene3D G3DSA:3.20.20.210 1 297 1.9E-71 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Mlab_0034 c9269b434371e53d2f9d300679febc91 297 SUPERFAMILY SSF51726 7 296 9.81E-54 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Mlab_0034 c9269b434371e53d2f9d300679febc91 297 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 7 291 3.5E-43 T 23-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 Mlab_0028 32ca9812db752aaffe8db347d294941a 245 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 171 1.4E-20 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase Mlab_0671 4987abf83c83ed338ccc6dbd3a8c8a2c 242 Gene3D G3DSA:3.40.50.300 1 236 2.7E-47 T 23-10-2018 Mlab_0671 4987abf83c83ed338ccc6dbd3a8c8a2c 242 SMART SM00382 26 213 1.6E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0671 4987abf83c83ed338ccc6dbd3a8c8a2c 242 Pfam PF00005 ABC transporter 17 158 1.8E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0671 4987abf83c83ed338ccc6dbd3a8c8a2c 242 SUPERFAMILY SSF52540 1 229 1.52E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0615 d84d5083d366063900e6718a22a3f76f 283 Gene3D G3DSA:3.40.50.720 2 136 8.2E-27 T 23-10-2018 Mlab_0615 d84d5083d366063900e6718a22a3f76f 283 Gene3D G3DSA:3.90.110.10 137 283 4.2E-22 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Mlab_0615 d84d5083d366063900e6718a22a3f76f 283 PRINTS PR00086 L-lactate dehydrogenase signature 3 27 8.7E-21 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Mlab_0615 d84d5083d366063900e6718a22a3f76f 283 PRINTS PR00086 L-lactate dehydrogenase signature 132 150 8.7E-21 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Mlab_0615 d84d5083d366063900e6718a22a3f76f 283 PRINTS PR00086 L-lactate dehydrogenase signature 158 171 8.7E-21 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Mlab_0615 d84d5083d366063900e6718a22a3f76f 283 PRINTS PR00086 L-lactate dehydrogenase signature 108 128 8.7E-21 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Mlab_0615 d84d5083d366063900e6718a22a3f76f 283 PRINTS PR00086 L-lactate dehydrogenase signature 28 52 8.7E-21 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Mlab_0615 d84d5083d366063900e6718a22a3f76f 283 PIRSF PIRSF000102 1 282 2.1E-47 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Mlab_0615 d84d5083d366063900e6718a22a3f76f 283 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 4 134 9.2E-19 T 23-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 Mlab_0615 d84d5083d366063900e6718a22a3f76f 283 SUPERFAMILY SSF56327 136 281 1.87E-25 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Mlab_0615 d84d5083d366063900e6718a22a3f76f 283 SUPERFAMILY SSF51735 4 136 4.81E-24 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0475 41b63da03f33f580fcc16f1fba697f3f 106 Pfam PF13371 Tetratricopeptide repeat 20 84 1.0E-9 T 23-10-2018 Mlab_0475 41b63da03f33f580fcc16f1fba697f3f 106 SUPERFAMILY SSF48452 7 101 2.74E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0475 41b63da03f33f580fcc16f1fba697f3f 106 SMART SM00028 43 76 6.7E-4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0475 41b63da03f33f580fcc16f1fba697f3f 106 SMART SM00028 9 42 56.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Mlab_0475 41b63da03f33f580fcc16f1fba697f3f 106 Gene3D G3DSA:1.25.40.10 6 106 1.1E-16 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0240 86c4dc7f7d4ee2d9cf0f30f16362e67f 308 TIGRFAM TIGR03288 CoB_CoM_SS_B: CoB--CoM heterodisulfide reductase, subunit B 7 304 1.3E-139 T 23-10-2018 IPR017678 CoB--CoM heterodisulphide reductase, subunit B GO:0015948|GO:0051186|GO:0051912|GO:0055114 Mlab_0240 86c4dc7f7d4ee2d9cf0f30f16362e67f 308 Gene3D G3DSA:3.40.50.11800 24 134 2.5E-5 T 23-10-2018 Mlab_0240 86c4dc7f7d4ee2d9cf0f30f16362e67f 308 Pfam PF02754 Cysteine-rich domain 155 252 3.0E-18 T 23-10-2018 IPR004017 Cysteine-rich domain Mlab_0240 86c4dc7f7d4ee2d9cf0f30f16362e67f 308 Pfam PF02754 Cysteine-rich domain 8 89 1.4E-11 T 23-10-2018 IPR004017 Cysteine-rich domain Mlab_1617 297400550de412bb248edb4c689cb6b4 202 PIRSF PIRSF000370 1 202 3.7E-69 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 Mlab_1617 297400550de412bb248edb4c689cb6b4 202 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 1 202 38.841 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 Mlab_1617 297400550de412bb248edb4c689cb6b4 202 Pfam PF04055 Radical SAM superfamily 26 102 5.2E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_1617 297400550de412bb248edb4c689cb6b4 202 Pfam PF13394 4Fe-4S single cluster domain 23 104 5.4E-13 T 23-10-2018 Mlab_1617 297400550de412bb248edb4c689cb6b4 202 Gene3D G3DSA:3.20.20.70 1 202 1.5E-41 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1617 297400550de412bb248edb4c689cb6b4 202 SUPERFAMILY SSF102114 12 108 8.76E-19 T 23-10-2018 Mlab_1394 7d24583c3e6540b1213a1bd44f86e498 392 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 52 375 5.9E-42 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Mlab_1394 7d24583c3e6540b1213a1bd44f86e498 392 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 79 93 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Mlab_1394 7d24583c3e6540b1213a1bd44f86e498 392 Gene3D G3DSA:3.40.50.1100 9 204 8.0E-174 T 23-10-2018 Mlab_1394 7d24583c3e6540b1213a1bd44f86e498 392 Gene3D G3DSA:3.40.50.1100 53 381 8.0E-174 T 23-10-2018 Mlab_1394 7d24583c3e6540b1213a1bd44f86e498 392 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 388 49.58 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Mlab_1394 7d24583c3e6540b1213a1bd44f86e498 392 SUPERFAMILY SSF53686 4 386 2.62E-138 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Mlab_1394 7d24583c3e6540b1213a1bd44f86e498 392 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 6 386 2.3E-181 T 23-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Mlab_1394 7d24583c3e6540b1213a1bd44f86e498 392 PIRSF PIRSF001413 1 392 3.5E-159 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Mlab_0819 94986e9573693cdae0f760244e83482b 125 SUPERFAMILY SSF52788 1 123 5.63E-34 T 23-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily Mlab_0819 94986e9573693cdae0f760244e83482b 125 Gene3D G3DSA:3.40.50.2300 1 125 4.6E-40 T 23-10-2018 Mlab_0819 94986e9573693cdae0f760244e83482b 125 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 123 5.0E-19 T 23-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Mlab_0819 94986e9573693cdae0f760244e83482b 125 SMART SM00226 2 125 6.1E-31 T 23-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Mlab_0861 98f843b23db5a5ec7f05c619d40058a9 64 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 3 64 8.0E-33 T 23-10-2018 IPR019240 Protein of unknown function DUF2196 Mlab_0861 98f843b23db5a5ec7f05c619d40058a9 64 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 4 63 5.7E-30 T 23-10-2018 IPR019240 Protein of unknown function DUF2196 Mlab_0503 91befd7cb19e04de2e1decfcb4d79844 412 Hamap MF_02109 Cysteate synthase. 1 412 55.9 T 23-10-2018 IPR022401 Cysteate synthase GO:0016765 MetaCyc: PWY-6643 Mlab_0503 91befd7cb19e04de2e1decfcb4d79844 412 SUPERFAMILY SSF53686 97 387 1.44E-35 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Mlab_0503 91befd7cb19e04de2e1decfcb4d79844 412 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 100 383 3.0E-33 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Mlab_0503 91befd7cb19e04de2e1decfcb4d79844 412 TIGRFAM TIGR03844 cysteate_syn: cysteate synthase 4 404 1.6E-203 T 23-10-2018 IPR022401 Cysteate synthase GO:0016765 MetaCyc: PWY-6643 Mlab_0503 91befd7cb19e04de2e1decfcb4d79844 412 Gene3D G3DSA:3.40.50.1100 73 387 7.5E-50 T 23-10-2018 Mlab_0503 91befd7cb19e04de2e1decfcb4d79844 412 Gene3D G3DSA:3.40.50.1100 104 202 7.5E-50 T 23-10-2018 Mlab_0502 880ac64ae982ef84a54b7e2c9059230c 408 SUPERFAMILY SSF54862 288 361 4.19E-8 T 23-10-2018 Mlab_0502 880ac64ae982ef84a54b7e2c9059230c 408 TIGRFAM TIGR03287 methan_mark_16: putative methanogenesis marker 16 metalloprotein 18 406 1.7E-135 T 23-10-2018 IPR017677 Putative methanogenesis marker 16 metalloprotein Mlab_0502 880ac64ae982ef84a54b7e2c9059230c 408 ProDom PD011569 METAL-BINDING IRON IRON-SULFUR 4FE-4S FERREDOXIN OXIDOREDUCTASE DOMAIN ELECTRON METHANOGENESIS A 16 312 9.0E-80 T 23-10-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation Mlab_0502 880ac64ae982ef84a54b7e2c9059230c 408 Pfam PF01837 Homocysteine biosynthesis enzyme, sulfur-incorporation 16 406 2.9E-89 T 23-10-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation Mlab_1261 b59965af636225e739f67fc557d6ce07 133 SUPERFAMILY SSF50475 1 132 1.23E-26 T 23-10-2018 Mlab_1261 b59965af636225e739f67fc557d6ce07 133 Gene3D G3DSA:2.30.110.10 3 133 6.8E-33 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Mlab_1261 b59965af636225e739f67fc557d6ce07 133 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 4 87 5.4E-18 T 23-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 Mlab_0590 3ebb3288b941237880da86bde691dfde 213 Pfam PF07812 TfuA-like protein 51 168 3.8E-43 T 23-10-2018 IPR012924 TfuA-like, core Mlab_0388 32b2ab27304aaa418cb16dc5fa62cfe2 447 SUPERFAMILY SSF53720 3 431 1.96E-100 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Mlab_0388 32b2ab27304aaa418cb16dc5fa62cfe2 447 PIRSF PIRSF036492 1 445 3.8E-148 T 23-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 Mlab_0388 32b2ab27304aaa418cb16dc5fa62cfe2 447 Gene3D G3DSA:3.40.605.10 9 415 2.0E-141 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Mlab_0388 32b2ab27304aaa418cb16dc5fa62cfe2 447 Pfam PF00171 Aldehyde dehydrogenase family 10 415 1.7E-74 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Mlab_0388 32b2ab27304aaa418cb16dc5fa62cfe2 447 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 198 205 - T 23-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Mlab_0388 32b2ab27304aaa418cb16dc5fa62cfe2 447 Gene3D G3DSA:3.40.309.10 202 395 2.0E-141 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Mlab_0388 32b2ab27304aaa418cb16dc5fa62cfe2 447 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 226 237 - T 23-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Mlab_0229 f09a8977192646eb1ed4ddd751cf3d9d 295 Pfam PF08489 Domain of unknown function (DUF1743) 155 241 2.6E-4 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 Mlab_0229 f09a8977192646eb1ed4ddd751cf3d9d 295 TIGRFAM TIGR03280 methan_mark_11: methanogenesis imperfect marker protein 11 15 293 2.8E-90 T 23-10-2018 IPR017674 Putative methanogenesis marker protein 11 Mlab_0229 f09a8977192646eb1ed4ddd751cf3d9d 295 Gene3D G3DSA:3.30.70.2200 146 286 6.1E-17 T 23-10-2018 Mlab_1042 33ba5b3c4a1b45acddb0a67692521a9b 260 SMART SM00382 27 215 6.7E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1042 33ba5b3c4a1b45acddb0a67692521a9b 260 Gene3D G3DSA:3.40.50.300 2 252 3.3E-57 T 23-10-2018 Mlab_1042 33ba5b3c4a1b45acddb0a67692521a9b 260 SUPERFAMILY SSF52540 3 228 1.66E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1042 33ba5b3c4a1b45acddb0a67692521a9b 260 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1042 33ba5b3c4a1b45acddb0a67692521a9b 260 Pfam PF00005 ABC transporter 19 166 1.8E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_1050 3fa7c4978196a3fc32cd2ca3e518cf0f 473 Gene3D G3DSA:1.20.1740.10 8 468 3.1E-35 T 23-10-2018 Mlab_1050 3fa7c4978196a3fc32cd2ca3e518cf0f 473 PIRSF PIRSF006060 4 472 9.2E-62 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 Mlab_1050 3fa7c4978196a3fc32cd2ca3e518cf0f 473 Pfam PF13520 Amino acid permease 11 449 6.7E-62 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 Mlab_1685 54de00dc789288c5c8d668a334f2ae96 128 SUPERFAMILY SSF47598 6 45 1.19E-7 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Mlab_1713 97c78a4ebcd13e975bab7d8c1023d876 321 SUPERFAMILY SSF103481 55 155 3.53E-7 T 23-10-2018 Mlab_1713 97c78a4ebcd13e975bab7d8c1023d876 321 Pfam PF00892 EamA-like transporter family 172 307 1.6E-8 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Mlab_0709 197335bba1821675acb86a04e40bb0e7 90 Pfam PF00708 Acylphosphatase 6 87 9.0E-19 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Mlab_0709 197335bba1821675acb86a04e40bb0e7 90 SUPERFAMILY SSF54975 3 88 3.27E-21 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Mlab_0709 197335bba1821675acb86a04e40bb0e7 90 Gene3D G3DSA:3.30.70.100 1 88 2.3E-20 T 23-10-2018 Mlab_1674 affd2fe30a18e8a21647d689cc6e21dc 232 SUPERFAMILY SSF89550 4 195 1.44E-47 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Mlab_1674 affd2fe30a18e8a21647d689cc6e21dc 232 Pfam PF13263 PHP-associated 140 194 1.0E-17 T 23-10-2018 Mlab_1674 affd2fe30a18e8a21647d689cc6e21dc 232 SMART SM00481 6 71 6.3E-15 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Mlab_1674 affd2fe30a18e8a21647d689cc6e21dc 232 Pfam PF02811 PHP domain 7 125 8.8E-12 T 23-10-2018 IPR004013 PHP domain GO:0003824 Mlab_1674 affd2fe30a18e8a21647d689cc6e21dc 232 Gene3D G3DSA:3.20.20.140 3 206 1.6E-53 T 23-10-2018 Mlab_0821 5aa79b8b6329629f0d3c341c34f4de51 148 Pfam PF01022 Bacterial regulatory protein, arsR family 44 90 4.3E-15 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0821 5aa79b8b6329629f0d3c341c34f4de51 148 Gene3D G3DSA:1.10.10.10 6 119 1.0E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0821 5aa79b8b6329629f0d3c341c34f4de51 148 SUPERFAMILY SSF46785 32 118 1.33E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0821 5aa79b8b6329629f0d3c341c34f4de51 148 SMART SM00418 37 114 3.5E-23 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0821 5aa79b8b6329629f0d3c341c34f4de51 148 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 4.1E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0821 5aa79b8b6329629f0d3c341c34f4de51 148 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 4.1E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0821 5aa79b8b6329629f0d3c341c34f4de51 148 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 86 101 4.1E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0821 5aa79b8b6329629f0d3c341c34f4de51 148 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 69 4.1E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_0448 ecd8a2fc45063d67045fb61cd23074ee 96 TIGRFAM TIGR01384 TFS_arch: transcription factor S 1 96 8.9E-23 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 Mlab_0448 ecd8a2fc45063d67045fb61cd23074ee 96 PIRSF PIRSF005586 1 96 1.5E-24 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 Mlab_0448 ecd8a2fc45063d67045fb61cd23074ee 96 SUPERFAMILY SSF57783 34 96 4.31E-21 T 23-10-2018 Mlab_0448 ecd8a2fc45063d67045fb61cd23074ee 96 SMART SM00440 55 94 1.4E-16 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 Mlab_0448 ecd8a2fc45063d67045fb61cd23074ee 96 Pfam PF01096 Transcription factor S-II (TFIIS) 55 93 3.5E-17 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 Mlab_0448 ecd8a2fc45063d67045fb61cd23074ee 96 Gene3D G3DSA:2.20.25.10 41 96 4.5E-22 T 23-10-2018 Mlab_0448 ecd8a2fc45063d67045fb61cd23074ee 96 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 57 92 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 Mlab_0494 0c927b7447a608192c709e03944d9166 67 SUPERFAMILY SSF47113 4 66 3.14E-18 T 23-10-2018 IPR009072 Histone-fold GO:0046982 Mlab_0494 0c927b7447a608192c709e03944d9166 67 Gene3D G3DSA:1.10.20.10 1 66 1.5E-18 T 23-10-2018 IPR009072 Histone-fold GO:0046982 Mlab_0494 0c927b7447a608192c709e03944d9166 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 3 64 1.1E-14 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain Mlab_0172 ca9c8a7a22e39f71c3ec91b1773ab033 493 Pfam PF02386 Cation transport protein 57 475 8.0E-33 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 Mlab_0386 d66174a0fcfa4672adf6c28151de1ba3 252 Hamap MF_01084 Diphthine synthase [dphB]. 1 251 32.571 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 Mlab_0386 d66174a0fcfa4672adf6c28151de1ba3 252 SUPERFAMILY SSF53790 1 249 7.72E-55 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Mlab_0386 d66174a0fcfa4672adf6c28151de1ba3 252 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 218 8.0E-21 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Mlab_0386 d66174a0fcfa4672adf6c28151de1ba3 252 TIGRFAM TIGR00522 dph5: diphthine synthase 1 250 8.8E-89 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 Mlab_0386 d66174a0fcfa4672adf6c28151de1ba3 252 Gene3D G3DSA:3.40.1010.10 1 112 6.8E-33 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Mlab_0386 d66174a0fcfa4672adf6c28151de1ba3 252 PIRSF PIRSF036432 1 251 8.8E-92 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 Mlab_0386 d66174a0fcfa4672adf6c28151de1ba3 252 Gene3D G3DSA:3.30.950.10 113 251 2.3E-43 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Mlab_1665 f438fd609b9c610e12500d28bc764a42 252 SUPERFAMILY SSF55347 119 220 1.11E-22 T 23-10-2018 Mlab_1665 f438fd609b9c610e12500d28bc764a42 252 Gene3D G3DSA:3.40.50.720 4 243 2.8E-71 T 23-10-2018 Mlab_1665 f438fd609b9c610e12500d28bc764a42 252 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 8 116 2.5E-14 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 Mlab_1665 f438fd609b9c610e12500d28bc764a42 252 PIRSF PIRSF005227 1 252 7.7E-74 T 23-10-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 Mlab_1665 f438fd609b9c610e12500d28bc764a42 252 Gene3D G3DSA:3.30.360.10 119 225 2.8E-71 T 23-10-2018 Mlab_1665 f438fd609b9c610e12500d28bc764a42 252 TIGRFAM TIGR03855 NAD_NadX: aspartate dehydrogenase 22 250 1.2E-89 T 23-10-2018 IPR022487 L-aspartate dehydrogenase, archaeal GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 Mlab_1665 f438fd609b9c610e12500d28bc764a42 252 SUPERFAMILY SSF51735 1 140 1.27E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_1665 f438fd609b9c610e12500d28bc764a42 252 Pfam PF01958 Domain of unknown function DUF108 153 237 6.2E-29 T 23-10-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 Mlab_0293 97d8ce3d36a5dc0eef74c12fdf5939a4 309 Pfam PF08902 Domain of unknown function (DUF1848) 2 262 5.7E-95 T 23-10-2018 IPR014998 Protein of unknown function DUF1848 Mlab_0197 ac928506de420a5a584293fab22695e9 197 SUPERFAMILY SSF46689 8 75 1.05E-15 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Mlab_0197 ac928506de420a5a584293fab22695e9 197 Pfam PF14278 Transcriptional regulator C-terminal region 94 169 3.2E-10 T 23-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type Mlab_0197 ac928506de420a5a584293fab22695e9 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 62 2.2E-10 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Mlab_0197 ac928506de420a5a584293fab22695e9 197 Gene3D G3DSA:1.10.357.10 7 189 1.2E-40 T 23-10-2018 Mlab_0018 6ee073b32597bf2efab03ce5ac8a1277 311 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 5 309 2.3E-104 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 Mlab_0018 6ee073b32597bf2efab03ce5ac8a1277 311 Gene3D G3DSA:3.10.270.10 14 303 3.8E-67 T 23-10-2018 Mlab_0018 6ee073b32597bf2efab03ce5ac8a1277 311 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 2 300 38.608 T 23-10-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 Mlab_0018 6ee073b32597bf2efab03ce5ac8a1277 311 Pfam PF02649 Type I GTP cyclohydrolase folE2 3 296 1.2E-76 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 Mlab_1607 7cdcdb5cd856be39b1169ab963bf9757 175 Gene3D G3DSA:3.90.75.20 24 124 5.4E-5 T 23-10-2018 Mlab_1607 7cdcdb5cd856be39b1169ab963bf9757 175 SUPERFAMILY SSF46689 127 165 7.89E-5 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Mlab_1607 7cdcdb5cd856be39b1169ab963bf9757 175 SUPERFAMILY SSF54060 28 120 6.12E-12 T 23-10-2018 Mlab_0107 29027cf9522e005c111df33fec071398 177 Gene3D G3DSA:3.40.50.300 1 172 2.8E-36 T 23-10-2018 Mlab_0107 29027cf9522e005c111df33fec071398 177 Pfam PF13189 Cytidylate kinase-like family 3 155 7.9E-21 T 23-10-2018 Mlab_0107 29027cf9522e005c111df33fec071398 177 Hamap MF_00239 Cytidylate kinase [cmk]. 1 174 42.353 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Mlab_0107 29027cf9522e005c111df33fec071398 177 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 2 170 1.5E-52 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Mlab_0107 29027cf9522e005c111df33fec071398 177 SUPERFAMILY SSF52540 2 171 3.17E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0354 95b1a782ff0f632452ef9b95ac1474f3 484 Pfam PF07690 Major Facilitator Superfamily 19 415 4.0E-50 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_0354 95b1a782ff0f632452ef9b95ac1474f3 484 Gene3D G3DSA:1.20.1250.20 266 484 2.5E-25 T 23-10-2018 Mlab_0354 95b1a782ff0f632452ef9b95ac1474f3 484 Gene3D G3DSA:1.20.1720.10 14 257 3.8E-47 T 23-10-2018 Mlab_0354 95b1a782ff0f632452ef9b95ac1474f3 484 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 424 1.1E-82 T 23-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 Mlab_0354 95b1a782ff0f632452ef9b95ac1474f3 484 SUPERFAMILY SSF103473 4 480 4.84E-64 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_0354 95b1a782ff0f632452ef9b95ac1474f3 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 7.8E-5 T 23-10-2018 Mlab_0354 95b1a782ff0f632452ef9b95ac1474f3 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 112 132 7.8E-5 T 23-10-2018 Mlab_0354 95b1a782ff0f632452ef9b95ac1474f3 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 7.8E-5 T 23-10-2018 Mlab_1100 1371fc9b6a54cd865a864687120bc441 217 Gene3D G3DSA:3.90.1490.10 139 210 3.7E-9 T 23-10-2018 Mlab_1100 1371fc9b6a54cd865a864687120bc441 217 Gene3D G3DSA:3.40.50.620 1 138 4.0E-28 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_1100 1371fc9b6a54cd865a864687120bc441 217 Pfam PF01902 Diphthamide synthase 1 192 9.1E-37 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 Mlab_1100 1371fc9b6a54cd865a864687120bc441 217 SUPERFAMILY SSF52402 1 213 1.99E-57 T 23-10-2018 Mlab_1100 1371fc9b6a54cd865a864687120bc441 217 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 192 1.1E-35 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 Mlab_0083 9d6a0f6069c8e39a1bb08763d21fe137 82 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 6 82 1.1E-28 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0083 9d6a0f6069c8e39a1bb08763d21fe137 82 Pfam PF00276 Ribosomal protein L23 3 62 4.5E-13 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Mlab_0083 9d6a0f6069c8e39a1bb08763d21fe137 82 Gene3D G3DSA:3.30.70.330 1 82 3.9E-23 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Mlab_0083 9d6a0f6069c8e39a1bb08763d21fe137 82 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 2 82 21.325 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Mlab_0083 9d6a0f6069c8e39a1bb08763d21fe137 82 SUPERFAMILY SSF54189 3 72 7.55E-19 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0465 fc721612f8938b86c20a55a381a49cf9 312 Gene3D G3DSA:3.40.190.10 36 273 4.3E-80 T 23-10-2018 Mlab_0465 fc721612f8938b86c20a55a381a49cf9 312 Gene3D G3DSA:3.40.190.10 111 236 4.3E-80 T 23-10-2018 Mlab_0465 fc721612f8938b86c20a55a381a49cf9 312 SUPERFAMILY SSF53850 33 277 2.83E-29 T 23-10-2018 Mlab_0465 fc721612f8938b86c20a55a381a49cf9 312 Pfam PF12849 PBP superfamily domain 27 267 1.7E-25 T 23-10-2018 IPR024370 PBP domain Mlab_1262 6ac103cbce36cc79dcd101fdb0cc9a24 213 Pfam PF09920 Uncharacterized protein conserved in archaea (DUF2150) 21 208 9.2E-61 T 23-10-2018 IPR014518 Uncharacterised conserved protein UCP022079 Mlab_0538 b00d283157a0ec5f16904ffef3bd8857 311 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 13 308 5.8E-114 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 Mlab_0538 b00d283157a0ec5f16904ffef3bd8857 311 Gene3D G3DSA:3.20.20.70 7 311 1.5E-92 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0538 b00d283157a0ec5f16904ffef3bd8857 311 Pfam PF04055 Radical SAM superfamily 64 237 1.6E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0538 b00d283157a0ec5f16904ffef3bd8857 311 SUPERFAMILY SSF102114 62 284 1.92E-21 T 23-10-2018 Mlab_0538 b00d283157a0ec5f16904ffef3bd8857 311 Pfam PF08608 Wyosine base formation 249 309 7.9E-20 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 Mlab_0438 82bb29f5dbf49cdeb6252be714d0e140 202 SUPERFAMILY SSF55486 37 189 2.78E-13 T 23-10-2018 Mlab_0438 82bb29f5dbf49cdeb6252be714d0e140 202 Pfam PF07998 Peptidase family M54 91 191 5.0E-21 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 Mlab_0438 82bb29f5dbf49cdeb6252be714d0e140 202 Gene3D G3DSA:3.40.390.10 1 192 2.9E-79 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 Mlab_0438 82bb29f5dbf49cdeb6252be714d0e140 202 PIRSF PIRSF005785 7 197 1.4E-41 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 Mlab_0348 fd09b04dbcd7b3820218154ba52e51d3 392 Pfam PF05889 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS 127 390 3.9E-16 T 23-10-2018 IPR008829 SepSecS/SepCysS family GO:0016740 Reactome: R-HSA-2408557 Mlab_0348 fd09b04dbcd7b3820218154ba52e51d3 392 Hamap MF_01675 O-phospho-L-seryl-tRNA:Cys-tRNA synthase. 1 388 55.968 T 23-10-2018 IPR013375 O-phosphoseryl-tRNA:Cys-tRNA synthase, archaea GO:0043766 KEGG: 00970+2.5.1.73|MetaCyc: PWY-6308 Mlab_0348 fd09b04dbcd7b3820218154ba52e51d3 392 Gene3D G3DSA:3.40.640.10 25 284 6.0E-133 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_0348 fd09b04dbcd7b3820218154ba52e51d3 392 SUPERFAMILY SSF53383 25 382 1.02E-45 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_0348 fd09b04dbcd7b3820218154ba52e51d3 392 Gene3D G3DSA:3.90.1150.10 14 385 6.0E-133 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_0348 fd09b04dbcd7b3820218154ba52e51d3 392 TIGRFAM TIGR02539 SepCysS: O-phospho-L-seryl-tRNA:Cys-tRNA synthase 11 387 4.0E-112 T 23-10-2018 IPR013375 O-phosphoseryl-tRNA:Cys-tRNA synthase, archaea GO:0043766 KEGG: 00970+2.5.1.73|MetaCyc: PWY-6308 Mlab_0219 44e3984ac71cd0e5ed1e11688d4de159 187 Pfam PF00156 Phosphoribosyl transferase domain 58 160 1.9E-12 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Mlab_0219 44e3984ac71cd0e5ed1e11688d4de159 187 Gene3D G3DSA:3.40.50.2020 2 187 1.8E-32 T 23-10-2018 Mlab_0219 44e3984ac71cd0e5ed1e11688d4de159 187 SUPERFAMILY SSF53271 3 181 3.41E-28 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like Mlab_0219 44e3984ac71cd0e5ed1e11688d4de159 187 Hamap MF_01467 Hypoxanthine/guanine phosphoribosyltransferase [hpt]. 3 183 38.062 T 23-10-2018 IPR026597 Hypoxanthine/guanine phosphoribosyltransferase-like Mlab_0077 3c07df62d94240c138045c660acb53aa 291 ProSitePatterns PS01235 PdxS/SNZ family signature. 204 222 - T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Mlab_0077 3c07df62d94240c138045c660acb53aa 291 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 8 285 1.0E-149 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Mlab_0077 3c07df62d94240c138045c660acb53aa 291 SUPERFAMILY SSF51366 17 266 5.65E-64 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_0077 3c07df62d94240c138045c660acb53aa 291 Pfam PF01680 SOR/SNZ family 7 211 2.4E-107 T 23-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Mlab_0077 3c07df62d94240c138045c660acb53aa 291 Gene3D G3DSA:3.20.20.70 1 289 1.0E-145 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0077 3c07df62d94240c138045c660acb53aa 291 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 3 291 50.003 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Mlab_0077 3c07df62d94240c138045c660acb53aa 291 PIRSF PIRSF029271 1 291 2.2E-145 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Mlab_1631 27ed928a1f06f434f731b939dbf9129a 170 Pfam PF09946 Predicted membrane protein (DUF2178) 7 88 1.8E-7 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane Mlab_0587 1c6b6e916fb88c26e255495051450126 201 Gene3D G3DSA:3.40.50.10630 16 169 1.5E-18 T 23-10-2018 Mlab_0587 1c6b6e916fb88c26e255495051450126 201 SUPERFAMILY SSF52141 23 181 1.96E-41 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Mlab_1746 37439077f912f6884456ae20905fe40a 234 SUPERFAMILY SSF52218 1 225 1.39E-32 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1746 37439077f912f6884456ae20905fe40a 234 Pfam PF03358 NADPH-dependent FMN reductase 1 146 2.1E-23 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Mlab_1746 37439077f912f6884456ae20905fe40a 234 Gene3D G3DSA:3.40.50.360 1 232 7.6E-44 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0949 079767300bbc993a864c0561f6a776b0 86 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 81 2.2E-18 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 Mlab_1703 b6661181e91edcefec746455fdf8f88c 345 Pfam PF01145 SPFH domain / Band 7 family 25 194 8.6E-37 T 23-10-2018 IPR001107 Band 7 domain Mlab_1703 b6661181e91edcefec746455fdf8f88c 345 SMART SM00244 21 178 8.1E-50 T 23-10-2018 IPR001107 Band 7 domain Mlab_1703 b6661181e91edcefec746455fdf8f88c 345 SUPERFAMILY SSF117892 52 185 1.22E-41 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily Mlab_1703 b6661181e91edcefec746455fdf8f88c 345 PRINTS PR00721 Stomatin signature 173 194 3.0E-33 T 23-10-2018 IPR001972 Stomatin family GO:0016020 Mlab_1703 b6661181e91edcefec746455fdf8f88c 345 PRINTS PR00721 Stomatin signature 75 96 3.0E-33 T 23-10-2018 IPR001972 Stomatin family GO:0016020 Mlab_1703 b6661181e91edcefec746455fdf8f88c 345 PRINTS PR00721 Stomatin signature 130 153 3.0E-33 T 23-10-2018 IPR001972 Stomatin family GO:0016020 Mlab_1703 b6661181e91edcefec746455fdf8f88c 345 PRINTS PR00721 Stomatin signature 28 50 3.0E-33 T 23-10-2018 IPR001972 Stomatin family GO:0016020 Mlab_1703 b6661181e91edcefec746455fdf8f88c 345 PRINTS PR00721 Stomatin signature 110 127 3.0E-33 T 23-10-2018 IPR001972 Stomatin family GO:0016020 Mlab_1703 b6661181e91edcefec746455fdf8f88c 345 PRINTS PR00721 Stomatin signature 154 172 3.0E-33 T 23-10-2018 IPR001972 Stomatin family GO:0016020 Mlab_1703 b6661181e91edcefec746455fdf8f88c 345 ProSitePatterns PS01270 Band 7 protein family signature. 134 162 - T 23-10-2018 IPR018080 Band 7/stomatin-like, conserved site Mlab_1703 b6661181e91edcefec746455fdf8f88c 345 Gene3D G3DSA:3.30.479.30 49 180 1.3E-45 T 23-10-2018 Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 Gene3D G3DSA:3.10.20.490 1021 1117 1.4E-9 T 23-10-2018 Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 SMART SM00089 749 834 8.1E-4 T 23-10-2018 IPR022409 PKD/Chitinase domain Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 SUPERFAMILY SSF49299 736 835 1.83E-8 T 23-10-2018 IPR035986 PKD domain superfamily Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 Pfam PF13360 PQQ-like domain 80 342 1.1E-18 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 SUPERFAMILY SSF50998 43 469 1.09E-35 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 Gene3D G3DSA:2.130.10.10 28 247 2.7E-24 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 Gene3D G3DSA:2.60.40.10 735 836 1.1E-8 T 23-10-2018 IPR013783 Immunoglobulin-like fold Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 Gene3D G3DSA:2.140.10.10 248 392 1.9E-11 T 23-10-2018 Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 Pfam PF00801 PKD domain 754 818 1.6E-7 T 23-10-2018 IPR000601 PKD domain Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 Pfam PF14478 Domain of unknown function (DUF4430) 1063 1114 6.0E-12 T 23-10-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 SMART SM00564 268 298 70.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 SMART SM00564 100 132 0.0025 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 SMART SM00564 144 177 130.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 SMART SM00564 311 344 0.82 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Mlab_1375 5ed0e82166cbe002d9b25c331c3b3169 1238 SMART SM00564 52 93 850.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Mlab_1447 b6ee68e81f985b34b908d5e6cfe8f914 280 Pfam PF13649 Methyltransferase domain 72 157 2.3E-8 T 23-10-2018 Mlab_1447 b6ee68e81f985b34b908d5e6cfe8f914 280 SUPERFAMILY SSF53335 34 265 1.4E-20 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1447 b6ee68e81f985b34b908d5e6cfe8f914 280 Gene3D G3DSA:3.40.50.150 16 169 2.1E-15 T 23-10-2018 Mlab_0225 c2968ab032f11a5b93563c01ff879416 276 Pfam PF04463 Protein of unknown function (DUF523) 3 126 2.5E-9 T 23-10-2018 IPR007553 Domain of unknown function DUF523 Mlab_0225 c2968ab032f11a5b93563c01ff879416 276 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 142 244 1.9E-25 T 23-10-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase Reactome: R-HSA-74259 Mlab_0225 c2968ab032f11a5b93563c01ff879416 276 SUPERFAMILY SSF52309 138 261 1.07E-32 T 23-10-2018 Mlab_0225 c2968ab032f11a5b93563c01ff879416 276 Gene3D G3DSA:3.40.50.450 137 272 5.7E-38 T 23-10-2018 Mlab_0649 0427b51ef924296fddbe3fe014ea350f 224 Pfam PF08939 Domain of unknown function (DUF1917) 120 204 5.5E-24 T 23-10-2018 IPR015034 Protein of unknown function DUF1917 Mlab_0649 0427b51ef924296fddbe3fe014ea350f 224 SUPERFAMILY SSF55418 23 223 7.45E-40 T 23-10-2018 IPR023398 Translation Initiation factor eIF- 4e-like Mlab_0649 0427b51ef924296fddbe3fe014ea350f 224 Gene3D G3DSA:3.30.760.10 113 223 2.4E-29 T 23-10-2018 IPR023398 Translation Initiation factor eIF- 4e-like Mlab_0094 11f0032852e4fb540000bd17873db0f3 171 Gene3D G3DSA:3.30.1440.10 1 170 2.5E-56 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0094 11f0032852e4fb540000bd17873db0f3 171 Pfam PF00281 Ribosomal protein L5 4 56 6.7E-16 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0094 11f0032852e4fb540000bd17873db0f3 171 PIRSF PIRSF002161 1 170 7.0E-45 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0094 11f0032852e4fb540000bd17873db0f3 171 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 1 171 38.598 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0094 11f0032852e4fb540000bd17873db0f3 171 SUPERFAMILY SSF55282 3 169 1.11E-45 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0094 11f0032852e4fb540000bd17873db0f3 171 Pfam PF00673 ribosomal L5P family C-terminus 60 143 2.6E-23 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1738 7f82af008badcefa096a869bbbf07d7c 349 SUPERFAMILY SSF102114 17 293 9.94E-39 T 23-10-2018 Mlab_1738 7f82af008badcefa096a869bbbf07d7c 349 Pfam PF04055 Radical SAM superfamily 60 220 9.3E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_1738 7f82af008badcefa096a869bbbf07d7c 349 TIGRFAM TIGR03957 rSAM_HmdB: 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB 16 331 6.4E-182 T 23-10-2018 IPR023858 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB Mlab_1738 7f82af008badcefa096a869bbbf07d7c 349 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 230 294 2.1E-6 T 23-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Mlab_1738 7f82af008badcefa096a869bbbf07d7c 349 SMART SM00729 52 262 4.1E-12 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Mlab_1738 7f82af008badcefa096a869bbbf07d7c 349 SMART SM00876 230 329 0.0012 T 23-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Mlab_1738 7f82af008badcefa096a869bbbf07d7c 349 Gene3D G3DSA:3.20.20.70 1 336 8.3E-55 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0901 3439309650731bc9c23230c4a7903ac5 372 Pfam PF00534 Glycosyl transferases group 1 191 347 8.0E-28 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 Mlab_0901 3439309650731bc9c23230c4a7903ac5 372 SUPERFAMILY SSF53756 6 370 3.14E-80 T 23-10-2018 Mlab_0901 3439309650731bc9c23230c4a7903ac5 372 Gene3D G3DSA:3.40.50.2000 3 185 1.2E-28 T 23-10-2018 Mlab_0901 3439309650731bc9c23230c4a7903ac5 372 Gene3D G3DSA:3.40.50.2000 186 370 1.2E-39 T 23-10-2018 Mlab_0901 3439309650731bc9c23230c4a7903ac5 372 Pfam PF13439 Glycosyltransferase Family 4 20 183 9.0E-26 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Mlab_1416 e1f8d6528284450fb867a4cca2c57033 88 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 9 87 1.6E-30 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 Mlab_1416 e1f8d6528284450fb867a4cca2c57033 88 Gene3D G3DSA:3.30.70.20 7 54 3.3E-5 T 23-10-2018 Mlab_1416 e1f8d6528284450fb867a4cca2c57033 88 Gene3D G3DSA:3.30.70.20 55 88 4.7E-5 T 23-10-2018 Mlab_1416 e1f8d6528284450fb867a4cca2c57033 88 SUPERFAMILY SSF54862 17 86 2.89E-19 T 23-10-2018 Mlab_1416 e1f8d6528284450fb867a4cca2c57033 88 Pfam PF12838 4Fe-4S dicluster domain 33 78 1.3E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_1416 e1f8d6528284450fb867a4cca2c57033 88 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_1090 83b20a068eec2fc48d7c8cd0182cf2f7 141 SUPERFAMILY SSF118196 6 139 2.75E-40 T 23-10-2018 IPR036413 YaeB-like superfamily Mlab_1090 83b20a068eec2fc48d7c8cd0182cf2f7 141 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 7 139 1.4E-38 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain Mlab_1090 83b20a068eec2fc48d7c8cd0182cf2f7 141 Gene3D G3DSA:2.40.30.70 7 141 3.9E-41 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily Mlab_1090 83b20a068eec2fc48d7c8cd0182cf2f7 141 Pfam PF01980 Uncharacterised protein family UPF0066 23 136 3.0E-30 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain Mlab_0030 ace7d22cb4269a5629ee7225406add9c 95 Pfam PF01844 HNH endonuclease 19 66 2.9E-7 T 23-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 Mlab_0030 ace7d22cb4269a5629ee7225406add9c 95 Gene3D G3DSA:3.30.40.60 2 93 2.1E-8 T 23-10-2018 Mlab_0507 42dea124c76ca218c837d0d193225ef6 373 PIRSF PIRSF029347 15 125 3.1E-17 T 23-10-2018 IPR014555 RecF-like Mlab_0507 42dea124c76ca218c837d0d193225ef6 373 PIRSF PIRSF029347 145 356 2.9E-23 T 23-10-2018 IPR014555 RecF-like Mlab_0507 42dea124c76ca218c837d0d193225ef6 373 Gene3D G3DSA:3.40.50.300 15 135 6.7E-10 T 23-10-2018 Mlab_0507 42dea124c76ca218c837d0d193225ef6 373 SUPERFAMILY SSF52540 16 345 3.55E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0507 42dea124c76ca218c837d0d193225ef6 373 Gene3D G3DSA:3.40.50.300 195 347 2.6E-7 T 23-10-2018 Mlab_0507 42dea124c76ca218c837d0d193225ef6 373 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 38 321 1.1E-21 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Mlab_1749 e81510e5ccd793f2046e912183984f8b 288 SMART SM00090 47 282 5.2E-88 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 Mlab_1749 e81510e5ccd793f2046e912183984f8b 288 Pfam PF01163 RIO1 family 89 270 8.9E-55 T 23-10-2018 Mlab_1749 e81510e5ccd793f2046e912183984f8b 288 Gene3D G3DSA:1.10.510.10 187 287 2.1E-30 T 23-10-2018 Mlab_1749 e81510e5ccd793f2046e912183984f8b 288 SUPERFAMILY SSF56112 79 265 2.84E-21 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily Mlab_1749 e81510e5ccd793f2046e912183984f8b 288 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 216 227 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 Mlab_1749 e81510e5ccd793f2046e912183984f8b 288 Gene3D G3DSA:3.30.200.20 75 179 7.9E-11 T 23-10-2018 Mlab_0799 f19ac4dbac90f4cad2fccb0209189177 210 SUPERFAMILY SSF53927 8 209 3.91E-38 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Mlab_0799 f19ac4dbac90f4cad2fccb0209189177 210 Pfam PF02634 FdhD/NarQ family 10 209 2.5E-34 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Mlab_0799 f19ac4dbac90f4cad2fccb0209189177 210 Gene3D G3DSA:3.40.140.10 96 210 5.2E-22 T 23-10-2018 Mlab_0799 f19ac4dbac90f4cad2fccb0209189177 210 Gene3D G3DSA:3.10.20.10 11 88 1.8E-13 T 23-10-2018 Mlab_1547 1149c1e411423047bc00801727b69cee 208 Pfam PF13346 ABC-2 family transporter protein 7 204 2.9E-43 T 23-10-2018 IPR025699 ABC-2 membrane transporter-like Mlab_1403 1b555184c20d919f2a78f6fe8bded0a3 140 Gene3D G3DSA:3.30.310.190 27 135 2.5E-16 T 23-10-2018 Mlab_1403 1b555184c20d919f2a78f6fe8bded0a3 140 PIRSF PIRSF022080 27 139 1.1E-18 T 23-10-2018 IPR016800 Uncharacterised conserved protein UCP022080 Mlab_0070 fdebfafb564d537e9494f4666745d874 142 SUPERFAMILY SSF46785 15 125 1.14E-25 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0070 fdebfafb564d537e9494f4666745d874 142 Pfam PF01638 HxlR-like helix-turn-helix 26 114 1.7E-20 T 23-10-2018 IPR002577 Helix-turn-helix, HxlR type Mlab_0070 fdebfafb564d537e9494f4666745d874 142 Gene3D G3DSA:1.10.10.10 12 138 3.9E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0007 75e7f151dc32e2131d870b65d9ceae61 144 Pfam PF12675 Protein of unknown function (DUF3795) 7 102 1.6E-14 T 23-10-2018 IPR024227 Protein of unknown function DUF3795 Mlab_1045 5088a1575941a7163088a087c2b9f305 277 Pfam PF02527 rRNA small subunit methyltransferase G 64 165 6.2E-5 T 23-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Mlab_1045 5088a1575941a7163088a087c2b9f305 277 SUPERFAMILY SSF53335 59 213 7.37E-17 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1045 5088a1575941a7163088a087c2b9f305 277 Gene3D G3DSA:3.40.50.150 37 173 5.5E-12 T 23-10-2018 Mlab_0655 45366aa60d5b147a46c04f760cd4ead1 97 Gene3D G3DSA:3.30.70.330 1 97 1.7E-26 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Mlab_0655 45366aa60d5b147a46c04f760cd4ead1 97 Pfam PF01282 Ribosomal protein S24e 21 96 7.1E-19 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0655 45366aa60d5b147a46c04f760cd4ead1 97 SUPERFAMILY SSF54189 1 97 8.63E-24 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_0655 45366aa60d5b147a46c04f760cd4ead1 97 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 97 16.06 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0655 45366aa60d5b147a46c04f760cd4ead1 97 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 78 2.0E-11 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1053 60759ae221653d02107fbe59dae4a451 223 Pfam PF01048 Phosphorylase superfamily 3 217 1.3E-30 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Mlab_1053 60759ae221653d02107fbe59dae4a451 223 Gene3D G3DSA:3.40.50.1580 1 223 1.4E-48 T 23-10-2018 Mlab_1053 60759ae221653d02107fbe59dae4a451 223 SUPERFAMILY SSF53167 1 222 6.41E-48 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 Mlab_0149 8ddc5865d2d8ea8a57b03a18bf3f51d0 75 SMART SM00651 7 72 1.0E-20 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type Mlab_0149 8ddc5865d2d8ea8a57b03a18bf3f51d0 75 Gene3D G3DSA:2.30.30.100 1 75 6.0E-22 T 23-10-2018 Mlab_0149 8ddc5865d2d8ea8a57b03a18bf3f51d0 75 SUPERFAMILY SSF50182 2 72 1.29E-18 T 23-10-2018 IPR010920 LSM domain superfamily Mlab_0149 8ddc5865d2d8ea8a57b03a18bf3f51d0 75 Pfam PF01423 LSM domain 12 72 1.6E-20 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type Mlab_1588 efc7bb858fc28808d722dc7aa874fd05 270 Pfam PF07786 Protein of unknown function (DUF1624) 19 252 5.2E-55 T 23-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 Mlab_1122 334611346745ca7ef420ab4ba692c77e 879 Gene3D G3DSA:3.40.50.620 187 416 2.6E-44 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_1122 334611346745ca7ef420ab4ba692c77e 879 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 691 710 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Mlab_1122 334611346745ca7ef420ab4ba692c77e 879 SUPERFAMILY SSF52402 194 372 2.33E-38 T 23-10-2018 Mlab_1122 334611346745ca7ef420ab4ba692c77e 879 Gene3D G3DSA:3.40.640.10 522 772 6.4E-137 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_1122 334611346745ca7ef420ab4ba692c77e 879 Gene3D G3DSA:3.90.1150.10 497 870 6.4E-137 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_1122 334611346745ca7ef420ab4ba692c77e 879 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 221 383 1.3E-36 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 Mlab_1122 334611346745ca7ef420ab4ba692c77e 879 SUPERFAMILY SSF53383 489 876 1.58E-109 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_1122 334611346745ca7ef420ab4ba692c77e 879 Pfam PF00266 Aminotransferase class-V 504 868 1.2E-119 T 23-10-2018 IPR000192 Aminotransferase class V domain Mlab_0487 c11077bb368250945a1922bc00f2546b 361 Gene3D G3DSA:3.30.1490.20 21 95 9.7E-63 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Mlab_0487 c11077bb368250945a1922bc00f2546b 361 Gene3D G3DSA:3.30.470.20 5 211 9.7E-63 T 23-10-2018 Mlab_0487 c11077bb368250945a1922bc00f2546b 361 Pfam PF08442 ATP-grasp domain 3 188 8.3E-52 T 23-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Mlab_0487 c11077bb368250945a1922bc00f2546b 361 Pfam PF00549 CoA-ligase 245 357 3.0E-14 T 23-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Mlab_0487 c11077bb368250945a1922bc00f2546b 361 Gene3D G3DSA:3.40.50.261 221 361 3.3E-46 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Mlab_0487 c11077bb368250945a1922bc00f2546b 361 PIRSF PIRSF001554 1 361 1.9E-119 T 23-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Mlab_0487 c11077bb368250945a1922bc00f2546b 361 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 360 2.0E-117 T 23-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Mlab_0487 c11077bb368250945a1922bc00f2546b 361 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 361 34.98 T 23-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Mlab_0487 c11077bb368250945a1922bc00f2546b 361 SUPERFAMILY SSF56059 1 211 1.34E-50 T 23-10-2018 Mlab_0487 c11077bb368250945a1922bc00f2546b 361 SUPERFAMILY SSF52210 221 360 1.05E-43 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Mlab_0487 c11077bb368250945a1922bc00f2546b 361 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 238 263 - T 23-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Mlab_0213 ae6ea3ad97d02a22abf34eddaaba343f 108 Gene3D G3DSA:3.30.1980.10 11 102 5.4E-23 T 23-10-2018 IPR036493 Hypothetical protein YunC superfamily Mlab_0213 ae6ea3ad97d02a22abf34eddaaba343f 108 SUPERFAMILY SSF102891 15 101 2.62E-20 T 23-10-2018 IPR036493 Hypothetical protein YunC superfamily Mlab_0213 ae6ea3ad97d02a22abf34eddaaba343f 108 Pfam PF08827 Domain of unknown function (DUF1805) 43 100 6.3E-21 T 23-10-2018 IPR014931 Protein of unknown function DUF1805 Mlab_1699 e621c80cb8a7da2b9477885fa6176022 1141 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 11 1140 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_1699 e621c80cb8a7da2b9477885fa6176022 1141 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1141 492.298 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_1699 e621c80cb8a7da2b9477885fa6176022 1141 Pfam PF03833 DNA polymerase II large subunit DP2 13 889 0.0 T 23-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_1699 e621c80cb8a7da2b9477885fa6176022 1141 PIRSF PIRSF016275 3 1141 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Mlab_0644 326dcd8d8454cb4cc31cf2507b9d81e1 155 SUPERFAMILY SSF52833 3 154 1.98E-42 T 23-10-2018 IPR036249 Thioredoxin-like superfamily Mlab_0644 326dcd8d8454cb4cc31cf2507b9d81e1 155 PIRSF PIRSF000239 1 155 7.6E-20 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Mlab_0644 326dcd8d8454cb4cc31cf2507b9d81e1 155 Pfam PF00578 AhpC/TSA family 6 132 4.6E-29 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Mlab_0644 326dcd8d8454cb4cc31cf2507b9d81e1 155 Gene3D G3DSA:3.40.30.10 2 153 3.7E-41 T 23-10-2018 Mlab_0360 1a92ae95e2c7b76f6c27965c5be41b87 241 SUPERFAMILY SSF51182 10 179 1.17E-28 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily Mlab_0360 1a92ae95e2c7b76f6c27965c5be41b87 241 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 34 181 2.0E-41 T 23-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 Mlab_0360 1a92ae95e2c7b76f6c27965c5be41b87 241 Gene3D G3DSA:2.60.120.10 7 190 4.3E-56 T 23-10-2018 IPR014710 RmlC-like jelly roll fold Mlab_1022 38cc256ef7a0eae6cc11e2df3d1f3259 407 Pfam PF01769 Divalent cation transporter 273 399 1.0E-15 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 Mlab_1022 38cc256ef7a0eae6cc11e2df3d1f3259 407 Pfam PF01769 Divalent cation transporter 62 188 1.1E-13 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 Mlab_1022 38cc256ef7a0eae6cc11e2df3d1f3259 407 Gene3D G3DSA:1.10.357.20 220 406 6.4E-8 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain Mlab_1022 38cc256ef7a0eae6cc11e2df3d1f3259 407 SUPERFAMILY SSF161093 21 194 2.09E-18 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 Mlab_1022 38cc256ef7a0eae6cc11e2df3d1f3259 407 SUPERFAMILY SSF161093 227 404 2.22E-21 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 Mlab_0350 31462ba6b6fdf32499cd8aee04761875 268 Pfam PF01925 Sulfite exporter TauE/SafE 10 265 9.1E-48 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 Mlab_1228 9abc9765ef5f0a6c91c0cfd738c12fea 183 Gene3D G3DSA:1.10.3210.10 1 141 9.3E-10 T 23-10-2018 Mlab_1228 9abc9765ef5f0a6c91c0cfd738c12fea 183 SMART SM00471 15 124 1.2E-5 T 23-10-2018 IPR003607 HD/PDEase domain Mlab_1228 9abc9765ef5f0a6c91c0cfd738c12fea 183 SUPERFAMILY SSF109604 15 113 3.43E-15 T 23-10-2018 Mlab_1228 9abc9765ef5f0a6c91c0cfd738c12fea 183 TIGRFAM TIGR00277 HDIG: HDIG domain 17 91 4.2E-12 T 23-10-2018 IPR006675 HDIG domain Mlab_1228 9abc9765ef5f0a6c91c0cfd738c12fea 183 Pfam PF01966 HD domain 21 113 4.2E-9 T 23-10-2018 IPR006674 HD domain Mlab_0203 02f346f989654eb18dfc41fe02c52643 166 PIRSF PIRSF005216 1 166 1.0E-58 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Mlab_0203 02f346f989654eb18dfc41fe02c52643 166 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 166 72.979 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Mlab_0203 02f346f989654eb18dfc41fe02c52643 166 SUPERFAMILY SSF56271 2 163 6.02E-43 T 23-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Mlab_0203 02f346f989654eb18dfc41fe02c52643 166 Gene3D G3DSA:3.50.20.10 1 165 1.8E-39 T 23-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Mlab_0203 02f346f989654eb18dfc41fe02c52643 166 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 3 165 1.6E-59 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Mlab_0203 02f346f989654eb18dfc41fe02c52643 166 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 2 165 1.9E-42 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Mlab_0203 02f346f989654eb18dfc41fe02c52643 166 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 4 102 1.0E-30 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Mlab_0382 25818e7575566a86500c74a9bbe8521f 97 Pfam PF11950 Protein of unknown function (DUF3467) 5 80 7.2E-17 T 23-10-2018 IPR021857 Protein of unknown function DUF3467 Mlab_1342 b55e8bf8dfb533c92ec72c294685de97 147 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 1 110 17.504 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 Mlab_1342 b55e8bf8dfb533c92ec72c294685de97 147 SUPERFAMILY SSF160350 1 108 1.83E-25 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 Mlab_1342 b55e8bf8dfb533c92ec72c294685de97 147 Gene3D G3DSA:3.30.70.3250 1 111 1.1E-28 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 Mlab_1342 b55e8bf8dfb533c92ec72c294685de97 147 Pfam PF01900 Rpp14/Pop5 family 13 108 2.1E-16 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 Mlab_0314 b182ea3666e02a31e3c61c8f5634fcb7 178 SUPERFAMILY SSF53639 8 175 7.85E-36 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Mlab_0314 b182ea3666e02a31e3c61c8f5634fcb7 178 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 170 2.8E-31 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal Mlab_0314 b182ea3666e02a31e3c61c8f5634fcb7 178 SMART SM01007 3 172 1.1E-38 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal Mlab_0314 b182ea3666e02a31e3c61c8f5634fcb7 178 Gene3D G3DSA:3.40.225.10 2 178 2.0E-46 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Mlab_1076 dd1e395f3a472fa63149a88dd0052a4e 176 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 7 123 5.8E-26 T 23-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 Mlab_1076 dd1e395f3a472fa63149a88dd0052a4e 176 SUPERFAMILY SSF53335 7 163 6.75E-27 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1076 dd1e395f3a472fa63149a88dd0052a4e 176 Pfam PF13649 Methyltransferase domain 28 97 1.2E-9 T 23-10-2018 Mlab_1076 dd1e395f3a472fa63149a88dd0052a4e 176 Gene3D G3DSA:3.40.50.150 2 175 9.1E-43 T 23-10-2018 Mlab_1432 3702eac16bcd39d9079526eccf8b60c1 384 TIGRFAM TIGR04440 glyco_TIGR04440: glycosyltransferase domain 18 239 2.0E-69 T 23-10-2018 IPR031042 Glycosyltransferase domain Mlab_1432 3702eac16bcd39d9079526eccf8b60c1 384 SUPERFAMILY SSF53448 17 197 1.31E-15 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1432 3702eac16bcd39d9079526eccf8b60c1 384 Gene3D G3DSA:3.90.550.10 4 209 7.2E-14 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0586 24f77c786fea5db9a41bb4c18f46eec1 125 SUPERFAMILY SSF54211 9 117 5.31E-24 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_0586 24f77c786fea5db9a41bb4c18f46eec1 125 Gene3D G3DSA:3.30.230.30 1 122 9.6E-25 T 23-10-2018 IPR036956 Impact, N-terminal domain superfamily Mlab_0586 24f77c786fea5db9a41bb4c18f46eec1 125 Pfam PF01205 Uncharacterized protein family UPF0029 14 114 2.0E-22 T 23-10-2018 IPR001498 Impact, N-terminal Mlab_0610 6395ae5de43077d32d6aca1745846cde 464 SUPERFAMILY SSF103473 3 455 1.31E-58 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_0610 6395ae5de43077d32d6aca1745846cde 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 389 408 7.8E-9 T 23-10-2018 Mlab_0610 6395ae5de43077d32d6aca1745846cde 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 126 150 7.8E-9 T 23-10-2018 Mlab_0610 6395ae5de43077d32d6aca1745846cde 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 5 29 7.8E-9 T 23-10-2018 Mlab_0610 6395ae5de43077d32d6aca1745846cde 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 151 175 7.8E-9 T 23-10-2018 Mlab_0610 6395ae5de43077d32d6aca1745846cde 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 96 116 7.8E-9 T 23-10-2018 Mlab_0610 6395ae5de43077d32d6aca1745846cde 464 Gene3D G3DSA:1.20.1250.20 248 453 4.6E-18 T 23-10-2018 Mlab_0610 6395ae5de43077d32d6aca1745846cde 464 Pfam PF07690 Major Facilitator Superfamily 7 398 1.8E-50 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_0610 6395ae5de43077d32d6aca1745846cde 464 Gene3D G3DSA:1.20.1720.10 2 242 1.2E-40 T 23-10-2018 Mlab_0850 59ecc228352d345c612a28471c99f8a0 834 Gene3D G3DSA:3.40.50.300 271 469 1.1E-12 T 23-10-2018 Mlab_0850 59ecc228352d345c612a28471c99f8a0 834 SMART SM00490 526 609 3.7E-4 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0850 59ecc228352d345c612a28471c99f8a0 834 Pfam PF00271 Helicase conserved C-terminal domain 498 609 6.3E-6 T 23-10-2018 IPR001650 Helicase, C-terminal Mlab_0850 59ecc228352d345c612a28471c99f8a0 834 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 284 626 4.4E-36 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core Mlab_0850 59ecc228352d345c612a28471c99f8a0 834 SUPERFAMILY SSF52540 282 610 5.62E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0850 59ecc228352d345c612a28471c99f8a0 834 SUPERFAMILY SSF109604 18 218 1.53E-9 T 23-10-2018 Mlab_0850 59ecc228352d345c612a28471c99f8a0 834 Gene3D G3DSA:1.10.3210.30 8 192 2.7E-15 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily Mlab_0850 59ecc228352d345c612a28471c99f8a0 834 Gene3D G3DSA:3.40.50.300 483 642 1.9E-13 T 23-10-2018 Mlab_0850 59ecc228352d345c612a28471c99f8a0 834 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 27 219 8.3E-30 T 23-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain Mlab_0850 59ecc228352d345c612a28471c99f8a0 834 Pfam PF00270 DEAD/DEAH box helicase 284 448 5.2E-7 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Mlab_0850 59ecc228352d345c612a28471c99f8a0 834 Pfam PF01966 HD domain 28 126 3.4E-7 T 23-10-2018 IPR006674 HD domain Mlab_0663 8b092925dc53242241b2a8cfaa89412c 376 Pfam PF00535 Glycosyl transferase family 2 48 208 6.6E-20 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Mlab_0663 8b092925dc53242241b2a8cfaa89412c 376 Gene3D G3DSA:3.90.550.10 30 265 7.1E-33 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0663 8b092925dc53242241b2a8cfaa89412c 376 SUPERFAMILY SSF53448 42 307 2.16E-40 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1092 dcb75ef0678ee93db627c531d0f49301 378 Pfam PF01497 Periplasmic binding protein 55 312 1.1E-19 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain Mlab_1092 dcb75ef0678ee93db627c531d0f49301 378 Gene3D G3DSA:3.40.50.1980 181 378 3.5E-58 T 23-10-2018 Mlab_1092 dcb75ef0678ee93db627c531d0f49301 378 Gene3D G3DSA:3.40.50.1980 31 179 9.6E-29 T 23-10-2018 Mlab_1092 dcb75ef0678ee93db627c531d0f49301 378 SUPERFAMILY SSF53807 37 339 4.32E-38 T 23-10-2018 Mlab_0209 d8e880668600383c13c73367f29751ad 129 SUPERFAMILY SSF52255 3 128 7.98E-43 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Mlab_0209 d8e880668600383c13c73367f29751ad 129 Pfam PF00731 AIR carboxylase 3 128 1.0E-42 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Mlab_0209 d8e880668600383c13c73367f29751ad 129 SMART SM01001 2 129 5.2E-42 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Mlab_0209 d8e880668600383c13c73367f29751ad 129 PIRSF PIRSF001338 1 129 8.2E-45 T 23-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 Mlab_0209 d8e880668600383c13c73367f29751ad 129 Gene3D G3DSA:3.40.50.7700 1 129 7.6E-47 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Mlab_1109 03a88455423f813fefc779b01fb8cad0 367 TIGRFAM TIGR03277 methan_mark_9: putative methanogenesis marker domain 9 254 362 2.5E-47 T 23-10-2018 IPR017671 Putative methanogenesis marker domain 9 Mlab_1109 03a88455423f813fefc779b01fb8cad0 367 Pfam PF01207 Dihydrouridine synthase (Dus) 92 234 1.6E-7 T 23-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Mlab_1109 03a88455423f813fefc779b01fb8cad0 367 Gene3D G3DSA:3.20.20.70 8 257 1.7E-19 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1109 03a88455423f813fefc779b01fb8cad0 367 SUPERFAMILY SSF51395 9 250 4.03E-26 T 23-10-2018 Mlab_1654 8bcdc409d66d2a300ca2caaf36a5d37f 264 SUPERFAMILY SSF51569 3 250 2.69E-78 T 23-10-2018 Mlab_1654 8bcdc409d66d2a300ca2caaf36a5d37f 264 SMART SM01133 19 235 1.2E-62 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Mlab_1654 8bcdc409d66d2a300ca2caaf36a5d37f 264 Hamap MF_00960 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [aroA']. 1 263 58.635 T 23-10-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 Mlab_1654 8bcdc409d66d2a300ca2caaf36a5d37f 264 TIGRFAM TIGR01949 AroFGH_arch: predicted phospho-2-dehydro-3-deoxyheptonate aldolase 3 259 5.4E-107 T 23-10-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 Mlab_1654 8bcdc409d66d2a300ca2caaf36a5d37f 264 Gene3D G3DSA:3.20.20.70 1 264 3.9E-89 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1654 8bcdc409d66d2a300ca2caaf36a5d37f 264 Pfam PF01791 DeoC/LacD family aldolase 20 235 1.2E-56 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Mlab_1654 8bcdc409d66d2a300ca2caaf36a5d37f 264 PIRSF PIRSF038992 1 264 4.0E-90 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Mlab_0277 008e92888089baa79f1b47c7515176dc 255 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 3 255 3.1E-86 T 23-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family Mlab_0277 008e92888089baa79f1b47c7515176dc 255 Gene3D G3DSA:3.50.50.60 1 255 1.3E-86 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0277 008e92888089baa79f1b47c7515176dc 255 SUPERFAMILY SSF51905 4 254 4.58E-41 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0277 008e92888089baa79f1b47c7515176dc 255 Pfam PF01946 Thi4 family 6 236 2.2E-67 T 23-10-2018 Mlab_0277 008e92888089baa79f1b47c7515176dc 255 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 1 255 36.242 T 23-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic Mlab_1503 2a0e323f9d60b38a45e8beba2d9ab817 284 Pfam PF01226 Formate/nitrite transporter 9 271 2.2E-73 T 23-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 Mlab_1503 2a0e323f9d60b38a45e8beba2d9ab817 284 Gene3D G3DSA:1.20.1080.10 1 263 2.4E-78 T 23-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 Mlab_1503 2a0e323f9d60b38a45e8beba2d9ab817 284 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 174 184 - T 23-10-2018 IPR024002 Formate/nitrite transporter, conserved site Mlab_1503 2a0e323f9d60b38a45e8beba2d9ab817 284 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 78 87 - T 23-10-2018 IPR024002 Formate/nitrite transporter, conserved site Mlab_0124 230d99cb64eecc3504e9e1a8c69227d2 218 Gene3D G3DSA:2.10.109.10 44 180 5.1E-6 T 23-10-2018 Mlab_0124 230d99cb64eecc3504e9e1a8c69227d2 218 SUPERFAMILY SSF51306 43 174 2.51E-9 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Mlab_0344 4b13278d5b229c3e49b85cae8650f7f2 279 Pfam PF00583 Acetyltransferase (GNAT) family 150 230 5.0E-6 T 23-10-2018 IPR000182 GNAT domain Mlab_0344 4b13278d5b229c3e49b85cae8650f7f2 279 Gene3D G3DSA:3.40.630.30 57 257 1.4E-13 T 23-10-2018 Mlab_0344 4b13278d5b229c3e49b85cae8650f7f2 279 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 13 279 5.9E-105 T 23-10-2018 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 Mlab_0344 4b13278d5b229c3e49b85cae8650f7f2 279 SUPERFAMILY SSF55729 127 277 5.15E-18 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_1005 06d1c4e0ddbfd346a824a2e160c27142 453 Gene3D G3DSA:1.20.1720.10 2 231 5.0E-38 T 23-10-2018 Mlab_1005 06d1c4e0ddbfd346a824a2e160c27142 453 Pfam PF07690 Major Facilitator Superfamily 7 393 2.0E-57 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_1005 06d1c4e0ddbfd346a824a2e160c27142 453 Gene3D G3DSA:1.20.1250.20 240 446 8.7E-23 T 23-10-2018 Mlab_1005 06d1c4e0ddbfd346a824a2e160c27142 453 SUPERFAMILY SSF103473 2 445 4.05E-63 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_1016 f8a8133f0e3529bf8f5ab242430599e7 239 SUPERFAMILY SSF56281 1 224 1.28E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1016 f8a8133f0e3529bf8f5ab242430599e7 239 Gene3D G3DSA:3.60.15.10 1 238 1.5E-57 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1016 f8a8133f0e3529bf8f5ab242430599e7 239 SMART SM00849 35 218 4.6E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1016 f8a8133f0e3529bf8f5ab242430599e7 239 Pfam PF12706 Beta-lactamase superfamily domain 46 219 2.4E-31 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1476 17f9f5a68c0048e476369473e481dbd1 679 Pfam PF03415 Clostripain family 39 363 3.5E-30 T 23-10-2018 IPR005077 Peptidase C11, clostripain Mlab_1086 f74a55f519366cda3cf55ef52965c1f0 135 SUPERFAMILY SSF53800 3 130 3.92E-28 T 23-10-2018 Mlab_1086 f74a55f519366cda3cf55ef52965c1f0 135 Pfam PF01903 CbiX 11 123 2.6E-23 T 23-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 Mlab_1086 f74a55f519366cda3cf55ef52965c1f0 135 Gene3D G3DSA:3.40.50.1400 2 134 1.8E-27 T 23-10-2018 Mlab_0112 cb36c0aa51a3194c50b3ad91315df01a 166 Gene3D G3DSA:1.20.1260.10 1 127 1.5E-33 T 23-10-2018 IPR012347 Ferritin-like Mlab_0112 cb36c0aa51a3194c50b3ad91315df01a 166 Pfam PF02915 Rubrerythrin 7 119 2.8E-13 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 Mlab_0112 cb36c0aa51a3194c50b3ad91315df01a 166 SUPERFAMILY SSF47240 3 128 3.44E-28 T 23-10-2018 IPR009078 Ferritin-like superfamily Mlab_0112 cb36c0aa51a3194c50b3ad91315df01a 166 Gene3D G3DSA:2.20.28.10 128 166 5.6E-12 T 23-10-2018 Mlab_0112 cb36c0aa51a3194c50b3ad91315df01a 166 SUPERFAMILY SSF57802 132 165 1.71E-8 T 23-10-2018 Mlab_0179 b4966dad8a05d2b604f4228b40b18e6e 257 Gene3D G3DSA:1.10.1760.20 75 243 1.5E-13 T 23-10-2018 Mlab_0179 b4966dad8a05d2b604f4228b40b18e6e 257 Pfam PF07694 5TMR of 5TMR-LYT 70 237 1.8E-40 T 23-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 Mlab_0268 0e5bf69bd9960f59803512701f6548a1 301 SUPERFAMILY SSF56059 86 262 6.72E-20 T 23-10-2018 Mlab_0268 0e5bf69bd9960f59803512701f6548a1 301 Gene3D G3DSA:3.30.1490.350 109 154 1.0E-39 T 23-10-2018 Mlab_0268 0e5bf69bd9960f59803512701f6548a1 301 Gene3D G3DSA:3.30.470.20 89 269 1.0E-39 T 23-10-2018 Mlab_0268 0e5bf69bd9960f59803512701f6548a1 301 Pfam PF02655 ATP-grasp domain 93 254 4.6E-26 T 23-10-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 Mlab_0268 0e5bf69bd9960f59803512701f6548a1 301 PIRSF PIRSF016766 1 301 3.1E-50 T 23-10-2018 IPR024710 Tyramine--L-glutamate ligase KEGG: 00680+6.3.4.24|MetaCyc: PWY-5254 Mlab_1594 f7c0a2ee34178b085c88ece2a6bd7a28 253 Pfam PF13263 PHP-associated 156 209 3.3E-15 T 23-10-2018 Mlab_1594 f7c0a2ee34178b085c88ece2a6bd7a28 253 SMART SM00481 1 59 1.0E-5 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Mlab_1594 f7c0a2ee34178b085c88ece2a6bd7a28 253 SUPERFAMILY SSF89550 1 205 1.94E-31 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Mlab_1594 f7c0a2ee34178b085c88ece2a6bd7a28 253 Gene3D G3DSA:3.20.20.140 1 220 6.1E-36 T 23-10-2018 Mlab_1718 d4de4f187f61894901c9fbd7211d8bf5 965 TIGRFAM TIGR04213 PGF_pre_PGF: PGF-pre-PGF domain 813 888 3.4E-8 T 23-10-2018 IPR026453 PGF-pre-PGF domain Mlab_0695 40b3896ba6e97b6757d34cee18feacab 175 SUPERFAMILY SSF54060 30 119 2.24E-12 T 23-10-2018 Mlab_0695 40b3896ba6e97b6757d34cee18feacab 175 Gene3D G3DSA:3.90.75.20 29 125 4.8E-6 T 23-10-2018 Mlab_0695 40b3896ba6e97b6757d34cee18feacab 175 SUPERFAMILY SSF46689 125 165 8.07E-5 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Mlab_1072 42ecb23a771e609e7e98ac76a8a85509 433 Gene3D G3DSA:3.40.50.300 10 47 1.7E-5 T 23-10-2018 Mlab_1072 42ecb23a771e609e7e98ac76a8a85509 433 Gene3D G3DSA:3.40.50.300 48 196 2.4E-20 T 23-10-2018 Mlab_1072 42ecb23a771e609e7e98ac76a8a85509 433 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 8 432 40.612 T 23-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 Mlab_1072 42ecb23a771e609e7e98ac76a8a85509 433 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 243 430 9.5E-39 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 Mlab_1072 42ecb23a771e609e7e98ac76a8a85509 433 SUPERFAMILY SSF52317 240 428 2.78E-29 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_1072 42ecb23a771e609e7e98ac76a8a85509 433 SUPERFAMILY SSF52540 9 199 4.56E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1072 42ecb23a771e609e7e98ac76a8a85509 433 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 10 432 3.2E-134 T 23-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 Mlab_1072 42ecb23a771e609e7e98ac76a8a85509 433 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 11 186 1.3E-16 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Mlab_1072 42ecb23a771e609e7e98ac76a8a85509 433 Gene3D G3DSA:3.40.50.880 239 396 4.8E-8 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0211 adc0a0f715aba4cca5bcdb56dfb42aca 98 Gene3D G3DSA:3.90.460.10 6 98 9.6E-19 T 23-10-2018 IPR036644 Ferredoxin thioredoxin reductase catalytic beta subunit superfamily GO:0016730|GO:0055114 Mlab_0211 adc0a0f715aba4cca5bcdb56dfb42aca 98 SUPERFAMILY SSF57662 12 97 2.88E-24 T 23-10-2018 IPR036644 Ferredoxin thioredoxin reductase catalytic beta subunit superfamily GO:0016730|GO:0055114 Mlab_0211 adc0a0f715aba4cca5bcdb56dfb42aca 98 Pfam PF02943 Ferredoxin thioredoxin reductase catalytic beta chain 15 97 3.0E-21 T 23-10-2018 IPR004209 Ferredoxin thioredoxin reductase catalytic beta subunit GO:0016730|GO:0055114 Mlab_1301 aeac27597108e43f069c41aafcf5aa41 92 SUPERFAMILY SSF57829 1 92 2.24E-30 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Mlab_1301 aeac27597108e43f069c41aafcf5aa41 92 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 91 23.643 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1301 aeac27597108e43f069c41aafcf5aa41 92 Gene3D G3DSA:3.10.450.80 1 92 6.1E-33 T 23-10-2018 Mlab_1301 aeac27597108e43f069c41aafcf5aa41 92 Pfam PF00935 Ribosomal protein L44 16 91 6.3E-25 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1301 aeac27597108e43f069c41aafcf5aa41 92 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 92 2.0E-35 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0602 9cd119b6f759910a02e7d9369d936827 330 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 42.817 T 23-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Mlab_0602 9cd119b6f759910a02e7d9369d936827 330 Gene3D G3DSA:3.40.50.720 1 181 5.6E-76 T 23-10-2018 Mlab_0602 9cd119b6f759910a02e7d9369d936827 330 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 326 1.3E-140 T 23-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Mlab_0602 9cd119b6f759910a02e7d9369d936827 330 PIRSF PIRSF000116 1 205 2.6E-40 T 23-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Mlab_0602 9cd119b6f759910a02e7d9369d936827 330 PIRSF PIRSF000116 201 330 5.1E-13 T 23-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Mlab_0602 9cd119b6f759910a02e7d9369d936827 330 SUPERFAMILY SSF48179 183 327 5.44E-65 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Mlab_0602 9cd119b6f759910a02e7d9369d936827 330 Gene3D G3DSA:1.10.3730.40 182 330 4.3E-66 T 23-10-2018 Mlab_0602 9cd119b6f759910a02e7d9369d936827 330 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 176 3.9E-75 T 23-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Mlab_0602 9cd119b6f759910a02e7d9369d936827 330 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 3.6E-63 T 23-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Mlab_0602 9cd119b6f759910a02e7d9369d936827 330 SUPERFAMILY SSF51735 2 182 6.08E-71 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0446 713c4c18f1cc2e24a649247b4735e406 152 Pfam PF01161 Phosphatidylethanolamine-binding protein 19 150 1.1E-8 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein Mlab_0446 713c4c18f1cc2e24a649247b4735e406 152 SUPERFAMILY SSF49777 17 136 1.44E-10 T 23-10-2018 IPR036610 PEBP-like superfamily Mlab_0446 713c4c18f1cc2e24a649247b4735e406 152 Gene3D G3DSA:3.90.280.10 7 151 1.7E-16 T 23-10-2018 IPR036610 PEBP-like superfamily Mlab_0746 0cc8b0f3c4a8c03c7dffe5881bacabe8 200 SUPERFAMILY SSF53448 1 187 1.08E-27 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0746 0cc8b0f3c4a8c03c7dffe5881bacabe8 200 Gene3D G3DSA:3.90.550.10 3 194 2.1E-37 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0746 0cc8b0f3c4a8c03c7dffe5881bacabe8 200 Pfam PF12804 MobA-like NTP transferase domain 3 120 1.9E-20 T 23-10-2018 IPR025877 MobA-like NTP transferase Mlab_1341 e937bab8ec1d87c69d35b9990c7581b4 272 SUPERFAMILY SSF56235 10 236 1.59E-74 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Mlab_1341 e937bab8ec1d87c69d35b9990c7581b4 272 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 11 33 - T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_1341 e937bab8ec1d87c69d35b9990c7581b4 272 Pfam PF10584 Proteasome subunit A N-terminal signature 11 33 1.3E-13 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_1341 e937bab8ec1d87c69d35b9990c7581b4 272 Pfam PF00227 Proteasome subunit 34 221 3.5E-56 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_1341 e937bab8ec1d87c69d35b9990c7581b4 272 SMART SM00948 11 33 5.0E-11 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Mlab_1341 e937bab8ec1d87c69d35b9990c7581b4 272 Gene3D G3DSA:3.60.20.10 6 269 3.3E-78 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Mlab_1341 e937bab8ec1d87c69d35b9990c7581b4 272 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 10 236 1.6E-98 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 Mlab_1341 e937bab8ec1d87c69d35b9990c7581b4 272 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 6 260 43.127 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 Mlab_0325 addae22415f18a497bbbc75bc2bf8feb 77 Pfam PF01423 LSM domain 11 75 8.4E-17 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type Mlab_0325 addae22415f18a497bbbc75bc2bf8feb 77 SUPERFAMILY SSF50182 5 76 1.28E-17 T 23-10-2018 IPR010920 LSM domain superfamily Mlab_0325 addae22415f18a497bbbc75bc2bf8feb 77 Gene3D G3DSA:2.30.30.100 3 76 7.6E-19 T 23-10-2018 Mlab_0325 addae22415f18a497bbbc75bc2bf8feb 77 PIRSF PIRSF006609 1 77 3.9E-18 T 23-10-2018 IPR016487 Sm-like protein Lsm6/SmF GO:0000398|GO:0005732 Reactome: R-HSA-72163 Mlab_0325 addae22415f18a497bbbc75bc2bf8feb 77 SMART SM00651 10 75 1.4E-15 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type Mlab_0910 175463f2b85120308dae1d860438c415 307 Gene3D G3DSA:3.90.25.10 173 301 1.1E-106 T 23-10-2018 Mlab_0910 175463f2b85120308dae1d860438c415 307 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 236 2.4E-62 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Mlab_0910 175463f2b85120308dae1d860438c415 307 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 1.0E-5 T 23-10-2018 Mlab_0910 175463f2b85120308dae1d860438c415 307 PRINTS PR01713 Nucleotide sugar epimerase signature 209 224 1.0E-5 T 23-10-2018 Mlab_0910 175463f2b85120308dae1d860438c415 307 PRINTS PR01713 Nucleotide sugar epimerase signature 269 286 1.0E-5 T 23-10-2018 Mlab_0910 175463f2b85120308dae1d860438c415 307 Gene3D G3DSA:3.40.50.720 4 236 1.1E-106 T 23-10-2018 Mlab_0910 175463f2b85120308dae1d860438c415 307 SUPERFAMILY SSF51735 1 306 1.38E-97 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0567 a44d560e38b66e8fd7a44c9f87f8fde1 213 Pfam PF10125 NADH dehydrogenase I, subunit N related protein 3 213 1.6E-97 T 23-10-2018 IPR017059 [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaH, predicted Mlab_0567 a44d560e38b66e8fd7a44c9f87f8fde1 213 PIRSF PIRSF036536 1 213 3.5E-66 T 23-10-2018 IPR017059 [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaH, predicted Mlab_0721 3b70f89b4a32b7c23dfde71ba41e61cf 225 Gene3D G3DSA:3.40.50.150 1 216 1.3E-45 T 23-10-2018 Mlab_0721 3b70f89b4a32b7c23dfde71ba41e61cf 225 SUPERFAMILY SSF53335 7 199 1.03E-49 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0721 3b70f89b4a32b7c23dfde71ba41e61cf 225 Pfam PF08241 Methyltransferase domain 49 143 7.2E-28 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Mlab_1179 e722abc5357fc5589fc1ff4b1912806c 506 Pfam PF00149 Calcineurin-like phosphoesterase 67 412 6.8E-8 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Mlab_1179 e722abc5357fc5589fc1ff4b1912806c 506 TIGRFAM TIGR03768 RPA4764: metallophosphoesterase, RPA4764 family 33 494 6.6E-226 T 23-10-2018 IPR022507 Metallophosphoesterase, RPA4764 Mlab_1179 e722abc5357fc5589fc1ff4b1912806c 506 Gene3D G3DSA:3.60.21.10 287 480 5.6E-14 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like Mlab_1179 e722abc5357fc5589fc1ff4b1912806c 506 SUPERFAMILY SSF56300 66 452 3.6E-35 T 23-10-2018 Mlab_1563 db652f325cb77f535d5ad0d3028c61c0 207 TIGRFAM TIGR03264 met_CoM_red_C: methyl-coenzyme M reductase I operon protein C 4 201 4.3E-87 T 23-10-2018 IPR007687 Methyl-coenzyme M reductase, protein C Mlab_1563 db652f325cb77f535d5ad0d3028c61c0 207 PIRSF PIRSF003137 2 207 1.9E-80 T 23-10-2018 IPR007687 Methyl-coenzyme M reductase, protein C Mlab_1563 db652f325cb77f535d5ad0d3028c61c0 207 Pfam PF04609 Methyl-coenzyme M reductase operon protein C 37 153 1.2E-6 T 23-10-2018 IPR026327 Methyl-coenzyme M reductase, protein C-like Mlab_0711 e51c4a7dc52d43a460488ecca4f6cbf2 256 SUPERFAMILY SSF56219 23 254 4.84E-23 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Mlab_0711 e51c4a7dc52d43a460488ecca4f6cbf2 256 Gene3D G3DSA:3.60.10.10 20 254 5.5E-25 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Mlab_1425 5492d494616cae3ec5399fd4eb297077 193 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 24 179 6.0E-48 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Mlab_1425 5492d494616cae3ec5399fd4eb297077 193 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 178 2.8E-61 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Mlab_1425 5492d494616cae3ec5399fd4eb297077 193 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 6 179 3.4E-47 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Mlab_1425 5492d494616cae3ec5399fd4eb297077 193 Gene3D G3DSA:2.60.120.10 4 183 2.2E-63 T 23-10-2018 IPR014710 RmlC-like jelly roll fold Mlab_1425 5492d494616cae3ec5399fd4eb297077 193 SUPERFAMILY SSF51182 4 184 2.59E-64 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily Mlab_0147 582b0cb05844e0b2ef56257944b33def 124 Pfam PF04472 Cell division protein SepF 42 116 3.5E-13 T 23-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 Mlab_0147 582b0cb05844e0b2ef56257944b33def 124 Gene3D G3DSA:3.30.110.150 40 123 1.3E-23 T 23-10-2018 IPR038594 SepF-like superfamily Mlab_0147 582b0cb05844e0b2ef56257944b33def 124 PIRSF PIRSF019313 1 124 7.2E-33 T 23-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea Mlab_0648 f403d657a85465b2a493face74bc5918 304 Hamap MF_00188 Protease HtpX [htpX]. 8 297 26.217 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 Mlab_0648 f403d657a85465b2a493face74bc5918 304 Gene3D G3DSA:3.30.2010.10 66 161 1.1E-28 T 23-10-2018 Mlab_0648 f403d657a85465b2a493face74bc5918 304 Pfam PF01435 Peptidase family M48 75 296 1.5E-39 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Mlab_0051 4a26d2dd6bee4f1b60897db16055f6dc 295 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 10 32 7.7E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal Mlab_0051 4a26d2dd6bee4f1b60897db16055f6dc 295 Pfam PF07790 Archaeal Type IV pilin, N-terminal 10 80 1.7E-12 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_1695 bd6b124f7bbeb7736353d51e9236dc10 227 Gene3D G3DSA:1.20.120.1630 38 226 3.4E-24 T 23-10-2018 Mlab_1695 bd6b124f7bbeb7736353d51e9236dc10 227 Pfam PF04191 Phospholipid methyltransferase 114 204 1.1E-10 T 23-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 Mlab_0643 d962199a91ef838e13d13d8d01c11645 225 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 6 222 1.2E-46 T 23-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 Mlab_0643 d962199a91ef838e13d13d8d01c11645 225 Gene3D G3DSA:3.40.430.10 5 224 1.8E-54 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Mlab_0643 d962199a91ef838e13d13d8d01c11645 225 Pfam PF01872 RibD C-terminal domain 7 218 5.3E-44 T 23-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Mlab_0643 d962199a91ef838e13d13d8d01c11645 225 SUPERFAMILY SSF53597 5 222 1.66E-50 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Mlab_0389 342a5e32136924b3d6b07e59e6b66311 336 Pfam PF00753 Metallo-beta-lactamase superfamily 67 271 1.9E-11 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0389 342a5e32136924b3d6b07e59e6b66311 336 SMART SM00849 68 272 7.7E-5 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0389 342a5e32136924b3d6b07e59e6b66311 336 SUPERFAMILY SSF56281 60 322 1.62E-47 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_0389 342a5e32136924b3d6b07e59e6b66311 336 Gene3D G3DSA:3.60.15.10 57 320 7.1E-68 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1496 3d498fe309287f83d17ccf97bfc0147f 672 Pfam PF10060 Uncharacterized membrane protein (DUF2298) 49 482 2.6E-87 T 23-10-2018 IPR018746 Protein of unknown function DUF2298 Mlab_1496 3d498fe309287f83d17ccf97bfc0147f 672 TIGRFAM TIGR03662 Chlor_Arch_YYY: chlor_Arch_YYY domain 7 672 5.8E-208 T 23-10-2018 IPR018746 Protein of unknown function DUF2298 Mlab_0764 02215e51097cde7cd5dc87d4da17e6e0 357 Gene3D G3DSA:3.90.180.10 22 342 2.8E-104 T 23-10-2018 Mlab_0764 02215e51097cde7cd5dc87d4da17e6e0 357 Gene3D G3DSA:3.40.50.720 166 296 2.8E-104 T 23-10-2018 Mlab_0764 02215e51097cde7cd5dc87d4da17e6e0 357 SUPERFAMILY SSF50129 6 186 1.52E-46 T 23-10-2018 IPR011032 GroES-like superfamily Mlab_0764 02215e51097cde7cd5dc87d4da17e6e0 357 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Mlab_0764 02215e51097cde7cd5dc87d4da17e6e0 357 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 132 5.2E-13 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Mlab_0764 02215e51097cde7cd5dc87d4da17e6e0 357 SUPERFAMILY SSF51735 144 317 5.17E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0764 02215e51097cde7cd5dc87d4da17e6e0 357 SMART SM00829 11 353 2.0E-4 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Mlab_0764 02215e51097cde7cd5dc87d4da17e6e0 357 Pfam PF00107 Zinc-binding dehydrogenase 181 269 2.4E-16 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Mlab_0372 f21484f8279ce8be9f26ee2b415de0e4 96 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 91 1.9E-14 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 Mlab_0372 f21484f8279ce8be9f26ee2b415de0e4 96 SUPERFAMILY SSF55315 1 92 2.94E-21 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like Mlab_0372 f21484f8279ce8be9f26ee2b415de0e4 96 Gene3D G3DSA:3.30.1330.30 1 96 5.9E-27 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like Mlab_1135 844090f9d7c0a589d35c919bc04802cd 300 SMART SM01133 32 270 7.7E-33 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Mlab_1135 844090f9d7c0a589d35c919bc04802cd 300 Gene3D G3DSA:3.20.20.70 1 300 4.6E-90 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1135 844090f9d7c0a589d35c919bc04802cd 300 PIRSF PIRSF038992 12 300 2.7E-65 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Mlab_1135 844090f9d7c0a589d35c919bc04802cd 300 SUPERFAMILY SSF51569 19 287 1.57E-61 T 23-10-2018 Mlab_1135 844090f9d7c0a589d35c919bc04802cd 300 Pfam PF01791 DeoC/LacD family aldolase 33 270 1.4E-43 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Mlab_1159 0c81af5ebb4705b8ff396886427b968e 783 Pfam PF12392 Collagenase 387 496 1.7E-18 T 23-10-2018 IPR020988 Peptidase U32, collagenase Mlab_1159 0c81af5ebb4705b8ff396886427b968e 783 Pfam PF01136 Peptidase family U32 77 302 9.9E-83 T 23-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Mlab_1159 0c81af5ebb4705b8ff396886427b968e 783 Pfam PF01136 Peptidase family U32 583 778 2.2E-24 T 23-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Mlab_1159 0c81af5ebb4705b8ff396886427b968e 783 SUPERFAMILY SSF51366 12 144 9.42E-5 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_0121 2a970fae8accc4138fcc6473fc980f7e 110 Pfam PF02627 Carboxymuconolactone decarboxylase family 23 100 6.6E-13 T 23-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Mlab_0121 2a970fae8accc4138fcc6473fc980f7e 110 Gene3D G3DSA:1.20.1290.10 1 109 2.9E-21 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Mlab_0121 2a970fae8accc4138fcc6473fc980f7e 110 SUPERFAMILY SSF69118 3 110 2.36E-22 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Mlab_0600 c7909e282c3ba237909173d5db5be728 265 SUPERFAMILY SSF51569 3 250 2.22E-77 T 23-10-2018 Mlab_0600 c7909e282c3ba237909173d5db5be728 265 SMART SM01133 19 234 9.0E-61 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Mlab_0600 c7909e282c3ba237909173d5db5be728 265 Hamap MF_00960 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [aroA']. 1 262 59.262 T 23-10-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 Mlab_0600 c7909e282c3ba237909173d5db5be728 265 Gene3D G3DSA:3.20.20.70 1 263 1.1E-88 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0600 c7909e282c3ba237909173d5db5be728 265 PIRSF PIRSF038992 1 264 9.7E-84 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Mlab_0600 c7909e282c3ba237909173d5db5be728 265 TIGRFAM TIGR01949 AroFGH_arch: predicted phospho-2-dehydro-3-deoxyheptonate aldolase 3 259 2.6E-102 T 23-10-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 Mlab_0600 c7909e282c3ba237909173d5db5be728 265 Pfam PF01791 DeoC/LacD family aldolase 19 234 2.3E-54 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Mlab_0612 04aab30880711562fa671e258fc02b0e 397 Pfam PF00557 Metallopeptidase family M24 144 380 3.1E-38 T 23-10-2018 IPR000994 Peptidase M24 Mlab_0612 04aab30880711562fa671e258fc02b0e 397 Pfam PF01321 Creatinase/Prolidase N-terminal domain 13 136 6.2E-12 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 Mlab_0612 04aab30880711562fa671e258fc02b0e 397 SUPERFAMILY SSF53092 27 136 7.85E-22 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Mlab_0612 04aab30880711562fa671e258fc02b0e 397 Gene3D G3DSA:3.90.230.10 136 393 3.7E-46 T 23-10-2018 Mlab_0612 04aab30880711562fa671e258fc02b0e 397 SUPERFAMILY SSF55920 138 388 2.09E-48 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like Mlab_0612 04aab30880711562fa671e258fc02b0e 397 Gene3D G3DSA:3.40.350.10 10 134 1.2E-11 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Mlab_0971 ecc1c6a1157e96984df1177bfb44460f 296 SUPERFAMILY SSF103481 36 138 1.31E-14 T 23-10-2018 Mlab_0971 ecc1c6a1157e96984df1177bfb44460f 296 SUPERFAMILY SSF103481 186 277 3.4E-13 T 23-10-2018 Mlab_0971 ecc1c6a1157e96984df1177bfb44460f 296 Pfam PF00892 EamA-like transporter family 146 276 1.7E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Mlab_0971 ecc1c6a1157e96984df1177bfb44460f 296 Pfam PF00892 EamA-like transporter family 9 135 8.2E-14 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Mlab_0304 6e99f6366f42a133cc3ea750a88e94dd 213 Pfam PF07853 Protein of unknown function (DUF1648) 12 59 5.1E-19 T 23-10-2018 IPR012867 Domain of unknown function DUF1648 Mlab_0304 6e99f6366f42a133cc3ea750a88e94dd 213 PIRSF PIRSF038959 1 212 3.5E-36 T 23-10-2018 IPR026272 Immunity protein SdpI Mlab_0304 6e99f6366f42a133cc3ea750a88e94dd 213 Pfam PF13630 SdpI/YhfL protein family 132 205 5.5E-23 T 23-10-2018 IPR025962 SdpI/YhfL protein family Mlab_0319 6ab28374bfc15c35f87aaf4900dadd96 491 SUPERFAMILY SSF102114 81 376 9.55E-46 T 23-10-2018 Mlab_0319 6ab28374bfc15c35f87aaf4900dadd96 491 Pfam PF13353 4Fe-4S single cluster domain 99 183 1.5E-7 T 23-10-2018 Mlab_0319 6ab28374bfc15c35f87aaf4900dadd96 491 Gene3D G3DSA:3.20.20.70 92 381 1.4E-35 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0319 6ab28374bfc15c35f87aaf4900dadd96 491 Pfam PF04055 Radical SAM superfamily 97 253 4.1E-19 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0589 bce8a9fbabbb7bf9c7e81e7f8725badc 236 SUPERFAMILY SSF69572 2 235 7.72E-83 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 Mlab_0589 bce8a9fbabbb7bf9c7e81e7f8725badc 236 Gene3D G3DSA:3.40.50.720 1 236 2.6E-80 T 23-10-2018 Mlab_0589 bce8a9fbabbb7bf9c7e81e7f8725badc 236 Pfam PF00899 ThiF family 5 230 3.3E-65 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 Mlab_1044 48f470f5ce3d4a5a8ebaf1c0e38cce18 397 Pfam PF01497 Periplasmic binding protein 134 327 5.1E-22 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain Mlab_1044 48f470f5ce3d4a5a8ebaf1c0e38cce18 397 Gene3D G3DSA:3.40.50.1980 53 393 1.4E-84 T 23-10-2018 Mlab_1044 48f470f5ce3d4a5a8ebaf1c0e38cce18 397 SUPERFAMILY SSF53807 64 389 5.89E-51 T 23-10-2018 Mlab_1756 d6e902a8183a527935a2a5c790d66d26 162 SMART SM00852 14 156 6.4E-30 T 23-10-2018 IPR001453 MoaB/Mog domain Mlab_1756 d6e902a8183a527935a2a5c790d66d26 162 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 11 151 5.4E-35 T 23-10-2018 IPR001453 MoaB/Mog domain Mlab_1756 d6e902a8183a527935a2a5c790d66d26 162 Pfam PF00994 Probable molybdopterin binding domain 14 154 2.9E-34 T 23-10-2018 IPR001453 MoaB/Mog domain Mlab_1756 d6e902a8183a527935a2a5c790d66d26 162 PIRSF PIRSF006443 1 162 2.2E-58 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 Mlab_1756 d6e902a8183a527935a2a5c790d66d26 162 Gene3D G3DSA:3.40.980.10 2 162 3.7E-46 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily Mlab_1756 d6e902a8183a527935a2a5c790d66d26 162 SUPERFAMILY SSF53218 10 160 2.75E-39 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily Mlab_1225 b294aa5e175e6b706334e875b76d80fc 316 Gene3D G3DSA:3.60.15.10 60 316 2.6E-22 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1225 b294aa5e175e6b706334e875b76d80fc 316 SUPERFAMILY SSF56281 88 315 1.97E-17 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1225 b294aa5e175e6b706334e875b76d80fc 316 SMART SM00849 88 310 2.8E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1225 b294aa5e175e6b706334e875b76d80fc 316 Pfam PF00753 Metallo-beta-lactamase superfamily 86 148 1.1E-4 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1459 e8620c665af12b5b068940784d4b3b48 770 Gene3D G3DSA:3.40.50.300 239 522 1.3E-88 T 23-10-2018 Mlab_1459 e8620c665af12b5b068940784d4b3b48 770 SUPERFAMILY SSF52540 122 446 3.21E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1459 e8620c665af12b5b068940784d4b3b48 770 Pfam PF00437 Type II/IV secretion system protein 148 402 9.4E-47 T 23-10-2018 IPR001482 Type II/IV secretion system protein Mlab_1459 e8620c665af12b5b068940784d4b3b48 770 Gene3D G3DSA:3.30.450.380 20 238 8.8E-65 T 23-10-2018 Mlab_0069 3554c8182010b0092a2b94823512bd60 648 Gene3D G3DSA:3.30.1330.20 238 369 7.4E-39 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 Mlab_0069 3554c8182010b0092a2b94823512bd60 648 Gene3D G3DSA:3.40.50.1440 1 237 7.7E-46 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Mlab_0069 3554c8182010b0092a2b94823512bd60 648 SUPERFAMILY SSF52490 1 202 2.35E-19 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Mlab_0928 81f2d441814c7ed2f821a6f19af99de3 228 Gene3D G3DSA:3.30.420.10 1 176 1.4E-37 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Mlab_0928 81f2d441814c7ed2f821a6f19af99de3 228 SUPERFAMILY SSF53098 2 222 2.72E-40 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily Mlab_0928 81f2d441814c7ed2f821a6f19af99de3 228 Pfam PF00929 Exonuclease 2 163 6.4E-24 T 23-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Mlab_0928 81f2d441814c7ed2f821a6f19af99de3 228 SMART SM00479 1 172 2.0E-28 T 23-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Mlab_0408 04f7c7cc6d5014230fe659606251ec97 140 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 65 3.6E-19 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Mlab_0408 04f7c7cc6d5014230fe659606251ec97 140 SUPERFAMILY SSF52374 1 132 4.22E-21 T 23-10-2018 Mlab_0408 04f7c7cc6d5014230fe659606251ec97 140 Gene3D G3DSA:3.40.50.620 1 120 3.8E-31 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0408 04f7c7cc6d5014230fe659606251ec97 140 Hamap MF_02115 FAD synthase [ribL]. 2 139 31.745 T 23-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0408 04f7c7cc6d5014230fe659606251ec97 140 Pfam PF01467 Cytidylyltransferase-like 5 131 6.0E-16 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Mlab_0773 cd9c86bad79ebbc053883c7189b5f397 367 Pfam PF00753 Metallo-beta-lactamase superfamily 92 261 2.4E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0773 cd9c86bad79ebbc053883c7189b5f397 367 SMART SM00849 92 321 0.0016 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0773 cd9c86bad79ebbc053883c7189b5f397 367 SUPERFAMILY SSF56281 90 326 3.93E-23 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_0773 cd9c86bad79ebbc053883c7189b5f397 367 Gene3D G3DSA:3.60.15.10 82 333 1.2E-22 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_1215 11440110c6b08405e371e264b9efe406 263 Gene3D G3DSA:3.40.50.150 79 250 3.1E-8 T 23-10-2018 Mlab_1215 11440110c6b08405e371e264b9efe406 263 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 86 223 3.0E-12 T 23-10-2018 IPR006342 Methyltransferase FkbM Mlab_1215 11440110c6b08405e371e264b9efe406 263 SUPERFAMILY SSF53335 54 238 2.06E-13 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1324 f77ae78de3b672a8bf1cd258e4e72f87 327 SUPERFAMILY SSF48239 51 225 1.23E-5 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Mlab_0722 5c5f4cde39402c991c5ba62f036cdf14 522 Gene3D G3DSA:3.40.190.10 66 264 2.4E-126 T 23-10-2018 Mlab_0722 5c5f4cde39402c991c5ba62f036cdf14 522 Gene3D G3DSA:3.10.105.10 265 479 2.4E-126 T 23-10-2018 Mlab_0722 5c5f4cde39402c991c5ba62f036cdf14 522 SUPERFAMILY SSF53850 36 517 9.05E-130 T 23-10-2018 Mlab_0722 5c5f4cde39402c991c5ba62f036cdf14 522 PIRSF PIRSF002741 6 520 8.6E-99 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Mlab_0722 5c5f4cde39402c991c5ba62f036cdf14 522 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 440 2.1E-88 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain Mlab_1114 8f354d3e8bda9100a1bdc03835fd1492 384 SUPERFAMILY SSF54862 304 371 2.17E-16 T 23-10-2018 Mlab_1114 8f354d3e8bda9100a1bdc03835fd1492 384 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 324 335 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_1114 8f354d3e8bda9100a1bdc03835fd1492 384 Pfam PF04015 Domain of unknown function (DUF362) 40 242 6.9E-45 T 23-10-2018 IPR007160 Domain of unknown function DUF362 Mlab_1114 8f354d3e8bda9100a1bdc03835fd1492 384 Gene3D G3DSA:3.30.70.20 312 375 2.2E-12 T 23-10-2018 Mlab_1114 8f354d3e8bda9100a1bdc03835fd1492 384 Pfam PF00037 4Fe-4S binding domain 317 338 4.2E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_1467 a808151d66db64cbfb6c6cabb8a13a0e 430 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 273 383 3.3E-9 T 23-10-2018 Mlab_1467 a808151d66db64cbfb6c6cabb8a13a0e 430 SUPERFAMILY SSF49899 274 422 9.18E-11 T 23-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Mlab_1467 a808151d66db64cbfb6c6cabb8a13a0e 430 Pfam PF07790 Archaeal Type IV pilin, N-terminal 5 72 1.3E-8 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_1467 a808151d66db64cbfb6c6cabb8a13a0e 430 Gene3D G3DSA:2.60.120.200 246 424 9.4E-11 T 23-10-2018 Mlab_1714 f4ddf1e6319eb067338ae02924363082 227 Gene3D G3DSA:3.40.50.150 2 227 8.0E-61 T 23-10-2018 Mlab_1714 f4ddf1e6319eb067338ae02924363082 227 SUPERFAMILY SSF53335 16 220 2.03E-33 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1714 f4ddf1e6319eb067338ae02924363082 227 Pfam PF13649 Methyltransferase domain 40 130 2.3E-12 T 23-10-2018 Mlab_0913 68adfc166b807e5fe52f019a258104f4 313 SUPERFAMILY SSF109604 158 278 6.28E-16 T 23-10-2018 Mlab_0913 68adfc166b807e5fe52f019a258104f4 313 Gene3D G3DSA:2.40.50.140 18 97 2.3E-6 T 23-10-2018 Mlab_0913 68adfc166b807e5fe52f019a258104f4 313 TIGRFAM TIGR00277 HDIG: HDIG domain 163 259 5.1E-8 T 23-10-2018 IPR006675 HDIG domain Mlab_0913 68adfc166b807e5fe52f019a258104f4 313 Gene3D G3DSA:1.10.3210.10 154 292 4.6E-11 T 23-10-2018 Mlab_0913 68adfc166b807e5fe52f019a258104f4 313 SMART SM00471 162 292 0.0036 T 23-10-2018 IPR003607 HD/PDEase domain Mlab_0913 68adfc166b807e5fe52f019a258104f4 313 Pfam PF01966 HD domain 168 279 1.0E-9 T 23-10-2018 IPR006674 HD domain Mlab_0332 8666d8b1307b72afbd7675d35ce59edf 278 Pfam PF02596 Uncharacterised ArCR, COG2043 6 256 1.9E-46 T 23-10-2018 IPR003748 Protein of unknown function DUF169 Mlab_0296 e7ffa6d36d3f0dc7dea0daf8a5a6f6c6 184 Pfam PF11193 Protein of unknown function (DUF2812) 11 120 5.3E-33 T 23-10-2018 IPR021359 Protein of unknown function DUF2812 Mlab_0921 85bc191e2ed6ce30cb56370fa4362136 278 PIRSF PIRSF016896 4 274 2.2E-59 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 Mlab_0921 85bc191e2ed6ce30cb56370fa4362136 278 Gene3D G3DSA:3.30.230.10 26 149 1.3E-11 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Mlab_0921 85bc191e2ed6ce30cb56370fa4362136 278 SUPERFAMILY SSF54211 5 148 2.58E-16 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_0921 85bc191e2ed6ce30cb56370fa4362136 278 Pfam PF00288 GHMP kinases N terminal domain 82 142 5.4E-7 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 Mlab_0082 5340ba6308c8c82e29b7fcc4241ef50a 247 SUPERFAMILY SSF52166 1 246 6.28E-58 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 Mlab_0082 5340ba6308c8c82e29b7fcc4241ef50a 247 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 246 3.0E-104 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Mlab_0082 5340ba6308c8c82e29b7fcc4241ef50a 247 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 247 39.773 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Mlab_0082 5340ba6308c8c82e29b7fcc4241ef50a 247 Pfam PF00573 Ribosomal protein L4/L1 family 16 246 3.3E-41 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 Mlab_0082 5340ba6308c8c82e29b7fcc4241ef50a 247 Gene3D G3DSA:3.40.1370.10 2 247 5.5E-81 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 Mlab_0196 1c10d7e9cd626cd1d3f884093e987589 234 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 12 232 1.0E-53 T 23-10-2018 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 Mlab_0196 1c10d7e9cd626cd1d3f884093e987589 234 SUPERFAMILY SSF51735 12 229 7.74E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0196 1c10d7e9cd626cd1d3f884093e987589 234 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 12 116 1.2E-16 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Mlab_0196 1c10d7e9cd626cd1d3f884093e987589 234 Gene3D G3DSA:3.40.50.720 12 234 6.4E-47 T 23-10-2018 Mlab_0245 97e444981328ded9b51672384be364bd 570 TIGRFAM TIGR03121 one_C_dehyd_A: formylmethanofuran dehydrogenase subunit A 3 559 7.6E-245 T 23-10-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A Mlab_0245 97e444981328ded9b51672384be364bd 570 PIRSF PIRSF006453 1 570 8.7E-239 T 23-10-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A Mlab_0245 97e444981328ded9b51672384be364bd 570 Gene3D G3DSA:2.30.40.10 1 71 3.6E-12 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_0245 97e444981328ded9b51672384be364bd 570 SUPERFAMILY SSF51556 53 458 3.01E-11 T 23-10-2018 IPR032466 Metal-dependent hydrolase Mlab_0245 97e444981328ded9b51672384be364bd 570 Pfam PF07969 Amidohydrolase family 41 504 6.5E-74 T 23-10-2018 IPR013108 Amidohydrolase 3 Mlab_0245 97e444981328ded9b51672384be364bd 570 SUPERFAMILY SSF51338 431 518 8.97E-14 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_0245 97e444981328ded9b51672384be364bd 570 SUPERFAMILY SSF51338 1 64 4.03E-16 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_1597 ef057477fe6fb5718b2fab77069f7564 538 Pfam PF08757 CotH kinase protein 289 482 4.4E-30 T 23-10-2018 IPR014867 Spore coat protein CotH Mlab_1597 ef057477fe6fb5718b2fab77069f7564 538 Pfam PF08757 CotH kinase protein 89 219 2.5E-28 T 23-10-2018 IPR014867 Spore coat protein CotH Mlab_0730 6bfe7c0c2a2cdc74d3a5ce6dd7f040ef 124 Gene3D G3DSA:1.10.10.10 42 97 1.4E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0730 6bfe7c0c2a2cdc74d3a5ce6dd7f040ef 124 Pfam PF02001 Protein of unknown function DUF134 12 101 3.6E-15 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 Mlab_0730 6bfe7c0c2a2cdc74d3a5ce6dd7f040ef 124 SUPERFAMILY SSF88659 46 94 3.18E-7 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Mlab_0847 4f8c49fe106cd431c2298c71c9cd1f66 307 Pfam PF05107 CRISPR-associated protein Cas7 6 294 4.8E-78 T 23-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C Mlab_0847 4f8c49fe106cd431c2298c71c9cd1f66 307 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 4 293 1.2E-67 T 23-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C Mlab_0847 4f8c49fe106cd431c2298c71c9cd1f66 307 TIGRFAM TIGR02589 cas_Csd2: CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG 7 294 1.2E-95 T 23-10-2018 IPR013418 CRISPR-associated protein Csd2 Mlab_1522 a7d4ce9bd7c0a6e1ccff3a5187c29c7a 126 Gene3D G3DSA:1.10.10.10 4 123 3.2E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1522 a7d4ce9bd7c0a6e1ccff3a5187c29c7a 126 SUPERFAMILY SSF46785 6 113 8.18E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1522 a7d4ce9bd7c0a6e1ccff3a5187c29c7a 126 Pfam PF01638 HxlR-like helix-turn-helix 21 110 5.3E-23 T 23-10-2018 IPR002577 Helix-turn-helix, HxlR type Mlab_0613 4dfda74fd20f4f499b097899d054b047 547 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Mlab_0613 4dfda74fd20f4f499b097899d054b047 547 SUPERFAMILY SSF143975 2 368 5.1E-133 T 23-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Mlab_0613 4dfda74fd20f4f499b097899d054b047 547 SUPERFAMILY SSF52016 369 545 4.94E-59 T 23-10-2018 Mlab_0613 4dfda74fd20f4f499b097899d054b047 547 Gene3D G3DSA:3.50.30.80 369 520 6.0E-55 T 23-10-2018 Mlab_0613 4dfda74fd20f4f499b097899d054b047 547 Pfam PF00920 Dehydratase family 31 544 1.6E-216 T 23-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Mlab_0613 4dfda74fd20f4f499b097899d054b047 547 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 547 45.816 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Mlab_0613 4dfda74fd20f4f499b097899d054b047 547 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 545 1.0E-237 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Mlab_0613 4dfda74fd20f4f499b097899d054b047 547 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 456 467 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Mlab_0334 018f06d43e9f03af203c49608ca83aed 79 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0334 018f06d43e9f03af203c49608ca83aed 79 Gene3D G3DSA:1.10.1060.10 24 77 3.1E-6 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Mlab_0334 018f06d43e9f03af203c49608ca83aed 79 SUPERFAMILY SSF46548 29 56 3.4E-5 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Mlab_0334 018f06d43e9f03af203c49608ca83aed 79 Pfam PF13534 4Fe-4S dicluster domain 9 47 7.2E-7 T 23-10-2018 Mlab_1075 09074916628d934ffbbd0dd99d51a0ef 109 Pfam PF14358 Domain of unknown function (DUF4405) 31 96 8.0E-15 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 Mlab_1075 09074916628d934ffbbd0dd99d51a0ef 109 SUPERFAMILY SSF81342 31 103 4.79E-6 T 23-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 Mlab_1130 9583eb2abfdabb35520beba9a951ba1d 125 Pfam PF03992 Antibiotic biosynthesis monooxygenase 29 104 1.4E-10 T 23-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain Mlab_1130 9583eb2abfdabb35520beba9a951ba1d 125 Gene3D G3DSA:3.30.70.100 5 125 2.4E-19 T 23-10-2018 Mlab_1130 9583eb2abfdabb35520beba9a951ba1d 125 SUPERFAMILY SSF54909 27 119 9.49E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel Mlab_0421 8612d0b0a44fdd4e508b2be079ea671d 300 Gene3D G3DSA:3.40.630.30 6 121 6.6E-79 T 23-10-2018 Mlab_0421 8612d0b0a44fdd4e508b2be079ea671d 300 PIRSF PIRSF018688 1 299 9.4E-80 T 23-10-2018 IPR016732 Uncharacterised conserved protein UCP018688 Mlab_0421 8612d0b0a44fdd4e508b2be079ea671d 300 SUPERFAMILY SSF55729 135 297 7.31E-46 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_0421 8612d0b0a44fdd4e508b2be079ea671d 300 SUPERFAMILY SSF55729 4 134 1.14E-29 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_0421 8612d0b0a44fdd4e508b2be079ea671d 300 Gene3D G3DSA:3.40.630.30 122 290 6.6E-79 T 23-10-2018 Mlab_0421 8612d0b0a44fdd4e508b2be079ea671d 300 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 22 291 3.1E-49 T 23-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal Mlab_1643 8ee0bed8a43ee653a098d4d5b039b40b 241 SUPERFAMILY SSF53474 4 234 2.78E-28 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold Mlab_1643 8ee0bed8a43ee653a098d4d5b039b40b 241 Gene3D G3DSA:3.40.50.1820 2 236 1.8E-24 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold Mlab_0534 709c60ca9b52c499f273f21c05588194 273 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 10 270 2.8E-94 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 Mlab_0534 709c60ca9b52c499f273f21c05588194 273 Pfam PF05681 Fumarate hydratase (Fumerase) 11 268 8.1E-91 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 Mlab_0495 854ad8322c37e0b694e8536885e6c55c 259 SUPERFAMILY SSF53659 15 235 1.82E-17 T 23-10-2018 Mlab_0495 854ad8322c37e0b694e8536885e6c55c 259 TIGRFAM TIGR03270 methan_mark_4: putative methanogen marker protein 4 51 243 3.3E-64 T 23-10-2018 IPR016764 Methyltransferase Mtx, subunit X GO:0008168 Mlab_1481 b90a4f2b034b962dbd9fb3962c86b2fc 199 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 3 145 2.4E-4 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 Mlab_1481 b90a4f2b034b962dbd9fb3962c86b2fc 199 SUPERFAMILY SSF52402 1 145 1.9E-21 T 23-10-2018 Mlab_1481 b90a4f2b034b962dbd9fb3962c86b2fc 199 Gene3D G3DSA:3.40.50.620 1 196 8.4E-57 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0524 c31473d579fe4900696e68223566ea90 315 Pfam PF00490 Delta-aminolevulinic acid dehydratase 2 312 5.0E-138 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Mlab_0524 c31473d579fe4900696e68223566ea90 315 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 113 127 1.2E-56 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Mlab_0524 c31473d579fe4900696e68223566ea90 315 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 233 249 1.2E-56 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Mlab_0524 c31473d579fe4900696e68223566ea90 315 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 288 307 1.2E-56 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Mlab_0524 c31473d579fe4900696e68223566ea90 315 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 143 162 1.2E-56 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Mlab_0524 c31473d579fe4900696e68223566ea90 315 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 181 200 1.2E-56 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Mlab_0524 c31473d579fe4900696e68223566ea90 315 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 258 273 1.2E-56 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Mlab_0524 c31473d579fe4900696e68223566ea90 315 SMART SM01004 1 314 1.3E-214 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Mlab_0524 c31473d579fe4900696e68223566ea90 315 SUPERFAMILY SSF51569 3 314 7.03E-128 T 23-10-2018 Mlab_0524 c31473d579fe4900696e68223566ea90 315 PIRSF PIRSF001415 1 315 1.8E-138 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Mlab_0524 c31473d579fe4900696e68223566ea90 315 Gene3D G3DSA:3.20.20.70 1 315 5.1E-137 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0524 c31473d579fe4900696e68223566ea90 315 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 233 245 - T 23-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Mlab_0919 e2117ca121bc3c807b9a625a8a2848a4 332 SUPERFAMILY SSF52540 3 229 4.84E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0919 e2117ca121bc3c807b9a625a8a2848a4 332 Gene3D G3DSA:1.10.8.60 179 247 1.7E-5 T 23-10-2018 Mlab_0919 e2117ca121bc3c807b9a625a8a2848a4 332 Pfam PF08542 Replication factor C C-terminal domain 252 321 2.5E-6 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 Mlab_0919 e2117ca121bc3c807b9a625a8a2848a4 332 Gene3D G3DSA:1.20.272.10 248 328 1.6E-7 T 23-10-2018 Mlab_0919 e2117ca121bc3c807b9a625a8a2848a4 332 SUPERFAMILY SSF48019 255 324 2.55E-7 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Mlab_0919 e2117ca121bc3c807b9a625a8a2848a4 332 Gene3D G3DSA:3.40.50.300 1 177 3.4E-35 T 23-10-2018 Mlab_0919 e2117ca121bc3c807b9a625a8a2848a4 332 Pfam PF13177 DNA polymerase III, delta subunit 17 178 4.3E-11 T 23-10-2018 Mlab_1088 01bc4b96f7fdc0697f385be43096c9ce 299 SUPERFAMILY SSF52540 43 265 5.03E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1088 01bc4b96f7fdc0697f385be43096c9ce 299 SMART SM00382 75 261 1.1E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_1088 01bc4b96f7fdc0697f385be43096c9ce 299 ProSitePatterns PS00211 ABC transporters family signature. 184 198 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1088 01bc4b96f7fdc0697f385be43096c9ce 299 Gene3D G3DSA:3.40.50.300 44 293 3.1E-60 T 23-10-2018 Mlab_1088 01bc4b96f7fdc0697f385be43096c9ce 299 Pfam PF00005 ABC transporter 66 212 3.7E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0950 8a593ecb2bfac68f6208f8070946f40a 124 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 8 108 1.5E-21 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 Mlab_0950 8a593ecb2bfac68f6208f8070946f40a 124 Pfam PF03334 Na+/H+ antiporter subunit 9 97 7.5E-24 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 Mlab_0347 c8838228ebc44ce96fd4aeb9f1fbd88e 245 Pfam PF07786 Protein of unknown function (DUF1624) 5 231 4.8E-61 T 23-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 Mlab_1288 e1cad92733a7a82d8a1058e364daee04 317 Gene3D G3DSA:3.40.50.1980 147 313 3.3E-48 T 23-10-2018 Mlab_1288 e1cad92733a7a82d8a1058e364daee04 317 Gene3D G3DSA:3.40.50.1980 32 146 1.4E-18 T 23-10-2018 Mlab_1288 e1cad92733a7a82d8a1058e364daee04 317 SUPERFAMILY SSF53807 43 317 2.38E-61 T 23-10-2018 Mlab_1288 e1cad92733a7a82d8a1058e364daee04 317 Pfam PF01497 Periplasmic binding protein 56 290 2.8E-30 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain Mlab_0274 fa31a5cf8c48ab9980cf29b8da5349de 168 SUPERFAMILY SSF52218 1 166 8.65E-40 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0274 fa31a5cf8c48ab9980cf29b8da5349de 168 Pfam PF03358 NADPH-dependent FMN reductase 49 121 7.2E-12 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Mlab_0274 fa31a5cf8c48ab9980cf29b8da5349de 168 Gene3D G3DSA:3.40.50.360 1 167 3.8E-48 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0757 57484d9f90788920224f8d68c0057fab 151 PIRSF PIRSF037663 4 143 1.8E-15 T 23-10-2018 IPR017255 Acetyltransferase, GNAT, predicted Mlab_0757 57484d9f90788920224f8d68c0057fab 151 SUPERFAMILY SSF55729 4 151 1.69E-25 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_0757 57484d9f90788920224f8d68c0057fab 151 Pfam PF00583 Acetyltransferase (GNAT) family 34 128 6.6E-15 T 23-10-2018 IPR000182 GNAT domain Mlab_0757 57484d9f90788920224f8d68c0057fab 151 Gene3D G3DSA:3.40.630.30 4 151 4.4E-29 T 23-10-2018 Mlab_0548 b645bcc8d964856b994aef5e42ae792e 144 Gene3D G3DSA:1.20.1290.10 12 135 1.7E-24 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Mlab_0548 b645bcc8d964856b994aef5e42ae792e 144 SUPERFAMILY SSF69118 10 128 9.81E-27 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Mlab_0548 b645bcc8d964856b994aef5e42ae792e 144 Pfam PF02627 Carboxymuconolactone decarboxylase family 58 129 6.4E-17 T 23-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Mlab_0548 b645bcc8d964856b994aef5e42ae792e 144 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 66 114 2.4E-12 T 23-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Mlab_1350 817c9c9ae65a09bba323bdb058027a5a 244 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 77 161 1.3E-6 T 23-10-2018 Mlab_1350 817c9c9ae65a09bba323bdb058027a5a 244 SUPERFAMILY SSF53335 9 243 2.86E-46 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_1350 817c9c9ae65a09bba323bdb058027a5a 244 Gene3D G3DSA:3.40.50.150 66 244 5.3E-33 T 23-10-2018 Mlab_1350 817c9c9ae65a09bba323bdb058027a5a 244 Gene3D G3DSA:3.10.330.20 5 60 7.0E-10 T 23-10-2018 Mlab_0006 8e2f0295b1fa7a581f72829cc74dc097 109 SUPERFAMILY SSF51182 12 108 7.32E-22 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily Mlab_0006 8e2f0295b1fa7a581f72829cc74dc097 109 Gene3D G3DSA:2.60.120.10 8 109 6.0E-32 T 23-10-2018 IPR014710 RmlC-like jelly roll fold Mlab_0006 8e2f0295b1fa7a581f72829cc74dc097 109 Pfam PF07883 Cupin domain 42 103 2.8E-10 T 23-10-2018 IPR013096 Cupin 2, conserved barrel Mlab_0115 ebd6f8357fcde51588b54596eb5bbe63 272 Pfam PF13197 Protein of unknown function (DUF4013) 92 237 9.9E-20 T 23-10-2018 IPR025098 Protein of unknown function DUF4013 Mlab_1056 e2b9c9197661960587958d3e9f215c9d 248 SUPERFAMILY SSF53146 139 246 6.8E-21 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Mlab_1056 e2b9c9197661960587958d3e9f215c9d 248 Gene3D G3DSA:3.30.420.130 137 247 3.2E-23 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Mlab_1056 e2b9c9197661960587958d3e9f215c9d 248 Gene3D G3DSA:3.30.420.130 3 108 2.5E-25 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Mlab_1056 e2b9c9197661960587958d3e9f215c9d 248 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 18 106 7.7E-19 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis Mlab_1056 e2b9c9197661960587958d3e9f215c9d 248 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 150 240 4.4E-20 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis Mlab_1056 e2b9c9197661960587958d3e9f215c9d 248 SUPERFAMILY SSF53146 12 125 1.57E-27 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Mlab_1448 1af401fd70b6c150d0eb819bf8b210f6 176 Pfam PF00881 Nitroreductase family 74 151 7.9E-12 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Mlab_1448 1af401fd70b6c150d0eb819bf8b210f6 176 Pfam PF00881 Nitroreductase family 16 71 4.4E-16 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Mlab_1448 1af401fd70b6c150d0eb819bf8b210f6 176 Gene3D G3DSA:3.40.109.10 13 176 4.3E-45 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Mlab_1448 1af401fd70b6c150d0eb819bf8b210f6 176 SUPERFAMILY SSF55469 15 176 7.2E-46 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Mlab_0210 74e717d561fcbf116edcffa8de3e81ba 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 260 3.1E-59 T 23-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Mlab_0210 74e717d561fcbf116edcffa8de3e81ba 263 SMART SM00079 33 262 0.0072 T 23-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 Mlab_0210 74e717d561fcbf116edcffa8de3e81ba 263 Gene3D G3DSA:3.40.190.10 119 219 6.2E-59 T 23-10-2018 Mlab_0210 74e717d561fcbf116edcffa8de3e81ba 263 Gene3D G3DSA:3.40.190.10 35 259 6.2E-59 T 23-10-2018 Mlab_0210 74e717d561fcbf116edcffa8de3e81ba 263 SUPERFAMILY SSF53850 4 260 1.31E-61 T 23-10-2018 Mlab_0210 74e717d561fcbf116edcffa8de3e81ba 263 SMART SM00062 33 263 3.7E-46 T 23-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Mlab_0977 0225bcdd11849bbc1e0895babff66512 245 PIRSF PIRSF006594 16 228 5.0E-50 T 23-10-2018 IPR002829 Protein of unknown function DUF116 Mlab_0977 0225bcdd11849bbc1e0895babff66512 245 Pfam PF01976 Protein of unknown function DUF116 70 221 5.0E-47 T 23-10-2018 IPR002829 Protein of unknown function DUF116 Mlab_1670 283d41cfde489fdad4dc02c3b5623e20 412 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 111 121 4.2E-7 T 23-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Mlab_1670 283d41cfde489fdad4dc02c3b5623e20 412 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 71 87 4.2E-7 T 23-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Mlab_1670 283d41cfde489fdad4dc02c3b5623e20 412 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 49 65 4.2E-7 T 23-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Mlab_1670 283d41cfde489fdad4dc02c3b5623e20 412 Pfam PF13458 Periplasmic binding protein 49 384 7.8E-38 T 23-10-2018 IPR028081 Leucine-binding protein domain Mlab_1670 283d41cfde489fdad4dc02c3b5623e20 412 SUPERFAMILY SSF53822 46 393 6.6E-65 T 23-10-2018 IPR028082 Periplasmic binding protein-like I Mlab_1670 283d41cfde489fdad4dc02c3b5623e20 412 Gene3D G3DSA:3.40.50.2300 166 297 2.2E-58 T 23-10-2018 Mlab_1670 283d41cfde489fdad4dc02c3b5623e20 412 Gene3D G3DSA:3.40.50.2300 51 367 2.2E-58 T 23-10-2018 Mlab_0987 4475542da2412ed2e6c2f36ee290c584 344 Pfam PF00682 HMGL-like 2 253 1.3E-38 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Mlab_0987 4475542da2412ed2e6c2f36ee290c584 344 SUPERFAMILY SSF51569 2 277 7.81E-56 T 23-10-2018 Mlab_0987 4475542da2412ed2e6c2f36ee290c584 344 Gene3D G3DSA:3.20.20.70 1 261 5.3E-73 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1303 686015c4558bb0e957a5e9a26cb92285 380 Pfam PF01896 DNA primase small subunit 102 313 1.4E-14 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 Mlab_1303 686015c4558bb0e957a5e9a26cb92285 380 Hamap MF_00700 DNA primase small subunit PriS [priS]. 7 372 25.807 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 Mlab_1303 686015c4558bb0e957a5e9a26cb92285 380 SUPERFAMILY SSF56747 1 376 8.94E-77 T 23-10-2018 Mlab_1303 686015c4558bb0e957a5e9a26cb92285 380 Gene3D G3DSA:3.90.920.30 250 380 6.4E-27 T 23-10-2018 Mlab_1303 686015c4558bb0e957a5e9a26cb92285 380 Gene3D G3DSA:3.90.920.30 1 114 8.0E-32 T 23-10-2018 Mlab_1303 686015c4558bb0e957a5e9a26cb92285 380 Gene3D G3DSA:3.90.920.30 115 211 1.1E-19 T 23-10-2018 Mlab_0208 896bae16d440be0a3aaf59e5f3db94e5 387 SUPERFAMILY SSF53383 15 372 3.02E-93 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_0208 896bae16d440be0a3aaf59e5f3db94e5 387 Gene3D G3DSA:3.90.1150.10 22 375 1.3E-117 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Mlab_0208 896bae16d440be0a3aaf59e5f3db94e5 387 Pfam PF00266 Aminotransferase class-V 18 355 1.8E-33 T 23-10-2018 IPR000192 Aminotransferase class V domain Mlab_0208 896bae16d440be0a3aaf59e5f3db94e5 387 Gene3D G3DSA:3.40.640.10 27 265 1.3E-117 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_0208 896bae16d440be0a3aaf59e5f3db94e5 387 PIRSF PIRSF000524 11 387 1.8E-119 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 Mlab_1231 4ba1e43f9ca292fa3501b7238969c64c 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 477 551 1.8E-9 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Mlab_1231 4ba1e43f9ca292fa3501b7238969c64c 562 Pfam PF00501 AMP-binding enzyme 38 467 7.1E-84 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Mlab_1231 4ba1e43f9ca292fa3501b7238969c64c 562 SUPERFAMILY SSF56801 18 561 1.57E-116 T 23-10-2018 Mlab_1231 4ba1e43f9ca292fa3501b7238969c64c 562 Gene3D G3DSA:3.40.50.12780 11 462 7.5E-92 T 23-10-2018 Mlab_1231 4ba1e43f9ca292fa3501b7238969c64c 562 Gene3D G3DSA:3.30.300.30 463 562 7.7E-19 T 23-10-2018 Mlab_1231 4ba1e43f9ca292fa3501b7238969c64c 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 209 220 - T 23-10-2018 IPR020845 AMP-binding, conserved site Mlab_1697 19e527a02be42e565390de5e38c93657 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.4E-10 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Mlab_1697 19e527a02be42e565390de5e38c93657 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.4E-10 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Mlab_1697 19e527a02be42e565390de5e38c93657 199 SUPERFAMILY SSF48498 97 184 9.54E-12 T 23-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Mlab_1697 19e527a02be42e565390de5e38c93657 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 7.0E-18 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Mlab_1697 19e527a02be42e565390de5e38c93657 199 SUPERFAMILY SSF46689 4 71 2.59E-18 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Mlab_1697 19e527a02be42e565390de5e38c93657 199 Gene3D G3DSA:1.10.357.10 10 191 5.1E-33 T 23-10-2018 Mlab_1659 7abbe24eed400e1f07cb8cfab56dab3d 213 SUPERFAMILY SSF51366 1 209 1.24E-42 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Mlab_1659 7abbe24eed400e1f07cb8cfab56dab3d 213 Gene3D G3DSA:3.20.20.70 1 211 9.9E-50 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_1659 7abbe24eed400e1f07cb8cfab56dab3d 213 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 212 28.627 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Mlab_1659 7abbe24eed400e1f07cb8cfab56dab3d 213 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 4 207 4.4E-27 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Mlab_0844 c9cff89ebc5b36c190bf0aa895939613 586 Gene3D G3DSA:3.40.50.12780 22 465 4.1E-140 T 23-10-2018 Mlab_0844 c9cff89ebc5b36c190bf0aa895939613 586 SUPERFAMILY SSF56801 24 571 7.59E-151 T 23-10-2018 Mlab_0844 c9cff89ebc5b36c190bf0aa895939613 586 Pfam PF13193 AMP-binding enzyme C-terminal domain 481 559 7.4E-25 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Mlab_0844 c9cff89ebc5b36c190bf0aa895939613 586 Pfam PF00501 AMP-binding enzyme 55 472 3.5E-83 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Mlab_0844 c9cff89ebc5b36c190bf0aa895939613 586 Gene3D G3DSA:3.30.300.30 468 585 9.5E-31 T 23-10-2018 Mlab_0289 6dbed64b1645862a3c658e2aa17c22a1 399 Pfam PF02272 DHHA1 domain 301 398 7.3E-10 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Mlab_0289 6dbed64b1645862a3c658e2aa17c22a1 399 Gene3D G3DSA:3.90.1640.30 1 171 1.0E-11 T 23-10-2018 Mlab_0289 6dbed64b1645862a3c658e2aa17c22a1 399 SUPERFAMILY SSF64182 2 397 1.31E-48 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily Mlab_0265 c176af65cd1a95d6fb08d27019c9667d 143 SUPERFAMILY SSF82649 4 122 1.18E-48 T 23-10-2018 Mlab_0265 c176af65cd1a95d6fb08d27019c9667d 143 TIGRFAM TIGR03419 NifU_clost: FeS cluster assembly scaffold protein NifU 2 120 5.2E-67 T 23-10-2018 IPR017787 NIF system FeS cluster assembly, NifU-like Mlab_0265 c176af65cd1a95d6fb08d27019c9667d 143 Gene3D G3DSA:3.90.1010.10 1 141 1.5E-60 T 23-10-2018 Mlab_0265 c176af65cd1a95d6fb08d27019c9667d 143 Pfam PF01592 NifU-like N terminal domain 1 121 5.2E-51 T 23-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 Mlab_0435 9824f2aa4e01da02d35614781dce2831 767 Pfam PF04312 Protein of unknown function (DUF460) 215 345 1.1E-41 T 23-10-2018 IPR007408 Protein of unknown function DUF460 Mlab_1537 71d1c4101d3dafeb3a4af793225879e3 583 Pfam PF00437 Type II/IV secretion system protein 212 459 8.7E-49 T 23-10-2018 IPR001482 Type II/IV secretion system protein Mlab_1537 71d1c4101d3dafeb3a4af793225879e3 583 SUPERFAMILY SSF52540 190 511 2.67E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1537 71d1c4101d3dafeb3a4af793225879e3 583 Gene3D G3DSA:3.30.450.380 88 307 2.8E-65 T 23-10-2018 Mlab_1537 71d1c4101d3dafeb3a4af793225879e3 583 Gene3D G3DSA:3.40.50.300 308 582 2.4E-87 T 23-10-2018 Mlab_1415 535cd22b3d5fa7a7c1cfb2a5c6c8ab54 182 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 174 9.7E-40 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Mlab_1415 535cd22b3d5fa7a7c1cfb2a5c6c8ab54 182 Gene3D G3DSA:3.40.920.10 1 179 2.0E-61 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Mlab_1415 535cd22b3d5fa7a7c1cfb2a5c6c8ab54 182 SUPERFAMILY SSF53323 2 179 7.72E-51 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Mlab_1415 535cd22b3d5fa7a7c1cfb2a5c6c8ab54 182 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 178 7.7E-68 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 Mlab_0041 5db1580f82bbd8f880909f6b8befe858 529 PIRSF PIRSF002741 1 524 3.2E-55 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Mlab_0041 5db1580f82bbd8f880909f6b8befe858 529 SUPERFAMILY SSF53850 48 514 6.99E-87 T 23-10-2018 Mlab_0041 5db1580f82bbd8f880909f6b8befe858 529 Gene3D G3DSA:3.40.190.10 21 274 5.2E-39 T 23-10-2018 Mlab_0041 5db1580f82bbd8f880909f6b8befe858 529 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 438 1.3E-59 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain Mlab_0041 5db1580f82bbd8f880909f6b8befe858 529 Gene3D G3DSA:3.10.105.10 275 495 3.6E-41 T 23-10-2018 Mlab_0008 92d7c3395a29e130ddc14853e343f79f 160 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 24 156 2.8E-30 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 Mlab_0008 92d7c3395a29e130ddc14853e343f79f 160 SUPERFAMILY SSF55729 15 159 2.45E-33 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_0008 92d7c3395a29e130ddc14853e343f79f 160 Pfam PF00583 Acetyltransferase (GNAT) family 25 137 4.3E-19 T 23-10-2018 IPR000182 GNAT domain Mlab_0008 92d7c3395a29e130ddc14853e343f79f 160 Gene3D G3DSA:3.40.630.30 14 160 3.1E-39 T 23-10-2018 Mlab_1750 5191a17b77ff9779500bd136987c1127 180 Gene3D G3DSA:3.30.1370.10 1 78 1.7E-24 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Mlab_1750 5191a17b77ff9779500bd136987c1127 180 Gene3D G3DSA:3.30.1370.10 80 180 7.1E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Mlab_1750 5191a17b77ff9779500bd136987c1127 180 SUPERFAMILY SSF54791 2 72 6.83E-10 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Mlab_1750 5191a17b77ff9779500bd136987c1127 180 Pfam PF00013 KH domain 2 48 4.8E-8 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 Mlab_1750 5191a17b77ff9779500bd136987c1127 180 SUPERFAMILY SSF54791 88 164 1.61E-14 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Mlab_1750 5191a17b77ff9779500bd136987c1127 180 SMART SM00322 1 64 0.0018 T 23-10-2018 IPR004087 K Homology domain GO:0003676 Mlab_1750 5191a17b77ff9779500bd136987c1127 180 SMART SM00322 90 153 0.29 T 23-10-2018 IPR004087 K Homology domain GO:0003676 Mlab_1750 5191a17b77ff9779500bd136987c1127 180 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 4 174 8.8E-67 T 23-10-2018 IPR019964 KH domain protein, archaea Mlab_0442 7a7b832ec564b59d794330e00bb6e772 172 Pfam PF01914 MarC family integral membrane protein 7 166 8.5E-29 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 Mlab_0547 bae13ecb1ace6e63d3aefc2b8da008d1 199 Pfam PF03641 Possible lysine decarboxylase 48 135 1.1E-5 T 23-10-2018 IPR031100 LOG family Mlab_0547 bae13ecb1ace6e63d3aefc2b8da008d1 199 SUPERFAMILY SSF102405 3 181 2.14E-29 T 23-10-2018 Mlab_0547 bae13ecb1ace6e63d3aefc2b8da008d1 199 Gene3D G3DSA:3.40.50.450 1 185 5.0E-35 T 23-10-2018 Mlab_1625 974cd90a8a2609151025da70f0194e0d 130 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 8 41 9.8E-10 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal Mlab_1625 974cd90a8a2609151025da70f0194e0d 130 Gene3D G3DSA:1.10.12.20 1 45 5.7E-9 T 23-10-2018 Mlab_1625 974cd90a8a2609151025da70f0194e0d 130 SUPERFAMILY SSF50249 4 112 1.37E-30 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold Mlab_1625 974cd90a8a2609151025da70f0194e0d 130 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 48 109 1.4E-18 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal Mlab_1049 990c30ea95ebf8d66237c16d87899351 232 Pfam PF02596 Uncharacterised ArCR, COG2043 9 215 1.4E-29 T 23-10-2018 IPR003748 Protein of unknown function DUF169 Mlab_0123 d649e0d2f80282333d266ad8e8a9dc64 361 Gene3D G3DSA:3.20.20.70 2 355 1.9E-47 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Mlab_0123 d649e0d2f80282333d266ad8e8a9dc64 361 Pfam PF04055 Radical SAM superfamily 61 230 8.6E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Mlab_0123 d649e0d2f80282333d266ad8e8a9dc64 361 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 51 361 8.8E-100 T 23-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 Mlab_0123 d649e0d2f80282333d266ad8e8a9dc64 361 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 17 360 1.4E-120 T 23-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 Mlab_0123 d649e0d2f80282333d266ad8e8a9dc64 361 SUPERFAMILY SSF102114 14 317 5.62E-36 T 23-10-2018 Mlab_0123 d649e0d2f80282333d266ad8e8a9dc64 361 PIRSF PIRSF004762 2 361 3.6E-97 T 23-10-2018 Mlab_0591 7f050b633d5136e8d3df1b737be33382 403 TIGRFAM TIGR03266 methan_mark_1: putative methanogenesis marker protein 1 15 390 1.4E-138 T 23-10-2018 IPR017667 Putative methanogenesis marker protein 1 Mlab_0591 7f050b633d5136e8d3df1b737be33382 403 Gene3D G3DSA:1.10.490.140 265 384 4.7E-9 T 23-10-2018 Mlab_0591 7f050b633d5136e8d3df1b737be33382 403 Gene3D G3DSA:1.10.490.140 157 258 1.7E-23 T 23-10-2018 Mlab_0591 7f050b633d5136e8d3df1b737be33382 403 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 70 377 8.0E-88 T 23-10-2018 IPR003776 YcaO-like domain Mlab_0591 7f050b633d5136e8d3df1b737be33382 403 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 19 388 2.8E-96 T 23-10-2018 IPR003776 YcaO-like domain Mlab_0281 5687f64b3577a12cb88380a4e73f628f 432 Pfam PF02450 Lecithin:cholesterol acyltransferase 96 214 4.2E-12 T 23-10-2018 IPR003386 Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase GO:0006629|GO:0008374 Mlab_0281 5687f64b3577a12cb88380a4e73f628f 432 SUPERFAMILY SSF53474 8 375 6.16E-20 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold Mlab_0812 e4b5937dcfbc37a836c5018985606348 132 Pfam PF10865 Domain of unknown function (DUF2703) 8 122 5.9E-35 T 23-10-2018 IPR021219 Protein of unknown function DUF2703 Mlab_0308 edc2f59b69b2fd96227d6368b819ecb6 347 SUPERFAMILY SSF51556 46 289 6.53E-36 T 23-10-2018 IPR032466 Metal-dependent hydrolase Mlab_0308 edc2f59b69b2fd96227d6368b819ecb6 347 SUPERFAMILY SSF51338 17 55 1.8E-5 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Mlab_0308 edc2f59b69b2fd96227d6368b819ecb6 347 Gene3D G3DSA:3.20.20.140 48 314 1.4E-24 T 23-10-2018 Mlab_0308 edc2f59b69b2fd96227d6368b819ecb6 347 Pfam PF00962 Adenosine/AMP deaminase 158 284 1.4E-10 T 23-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 Mlab_1707 30d5164cbe4bbad6d7b4fec56801cb79 348 SUPERFAMILY SSF53474 121 207 8.95E-7 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold Mlab_1707 30d5164cbe4bbad6d7b4fec56801cb79 348 Pfam PF11288 Protein of unknown function (DUF3089) 72 260 4.9E-58 T 23-10-2018 IPR021440 Protein of unknown function DUF3089 Mlab_0917 af493129af3154ec2f958bb86c94ceef 607 SUPERFAMILY SSF48452 37 271 5.22E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Mlab_0199 42382cc247d930584f7b550607b38769 200 Gene3D G3DSA:3.60.15.10 5 194 4.6E-43 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_0199 42382cc247d930584f7b550607b38769 200 SUPERFAMILY SSF56281 10 184 2.62E-38 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_0199 42382cc247d930584f7b550607b38769 200 SMART SM00849 14 177 2.9E-26 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0199 42382cc247d930584f7b550607b38769 200 Pfam PF00753 Metallo-beta-lactamase superfamily 21 177 5.6E-19 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_1692 aabcc9d20564bfd31d39690c2a8417c2 235 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 123 213 3.9E-13 T 23-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 Mlab_1692 aabcc9d20564bfd31d39690c2a8417c2 235 Gene3D G3DSA:1.20.120.1630 45 234 1.2E-30 T 23-10-2018 Mlab_1610 caf0174a064d8877d48d48ab574c6e6f 151 Pfam PF13366 PD-(D/E)XK nuclease superfamily 21 135 4.4E-40 T 23-10-2018 IPR026350 GxxExxY protein Mlab_1610 caf0174a064d8877d48d48ab574c6e6f 151 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 21 136 3.1E-41 T 23-10-2018 IPR026350 GxxExxY protein Mlab_0866 07b99ce43e56f6b8b37c814b598f3b2c 500 Gene3D G3DSA:3.10.20.70 25 125 3.0E-18 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Mlab_0866 07b99ce43e56f6b8b37c814b598f3b2c 500 SUPERFAMILY SSF55931 128 467 3.14E-52 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Mlab_0866 07b99ce43e56f6b8b37c814b598f3b2c 500 SUPERFAMILY SSF54368 25 125 2.35E-20 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Mlab_0866 07b99ce43e56f6b8b37c814b598f3b2c 500 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 37 119 1.5E-16 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Mlab_0866 07b99ce43e56f6b8b37c814b598f3b2c 500 SMART SM01230 126 397 6.0E-51 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Mlab_0866 07b99ce43e56f6b8b37c814b598f3b2c 500 Gene3D G3DSA:3.30.590.10 129 474 1.0E-63 T 23-10-2018 Mlab_0866 07b99ce43e56f6b8b37c814b598f3b2c 500 Pfam PF00120 Glutamine synthetase, catalytic domain 128 458 1.2E-41 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Mlab_0927 2b9eb428c0dff5326a27390469b39a9f 109 Gene3D G3DSA:3.30.460.10 5 101 5.6E-24 T 23-10-2018 Mlab_0927 2b9eb428c0dff5326a27390469b39a9f 109 SUPERFAMILY SSF81301 4 99 2.86E-23 T 23-10-2018 Mlab_0927 2b9eb428c0dff5326a27390469b39a9f 109 Pfam PF01909 Nucleotidyltransferase domain 22 101 1.9E-13 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Mlab_0262 e858982b56c4f8f8afa2a006d88c373d 107 SUPERFAMILY SSF47413 15 58 1.76E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Mlab_1504 b799ee6ee614919e131a0a2ec19899cc 251 Pfam PF01226 Formate/nitrite transporter 9 251 2.3E-65 T 23-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 Mlab_1504 b799ee6ee614919e131a0a2ec19899cc 251 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 174 184 - T 23-10-2018 IPR024002 Formate/nitrite transporter, conserved site Mlab_1504 b799ee6ee614919e131a0a2ec19899cc 251 Gene3D G3DSA:1.20.1080.10 1 251 5.1E-73 T 23-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 Mlab_0813 e85b5196077b620f01cda345b8ccaf75 78 Pfam PF08859 DGC domain 4 73 7.4E-18 T 23-10-2018 IPR014958 DGC Mlab_0221 070b17b3423c20d25a60b39e517681fb 185 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 3 183 23.911 T 23-10-2018 IPR022929 Putative manganese efflux pump MntP Mlab_0221 070b17b3423c20d25a60b39e517681fb 185 Pfam PF02659 Putative manganese efflux pump 36 180 4.8E-42 T 23-10-2018 IPR003810 Putative manganese efflux pump Mlab_1348 09e4d5c42ae3c6708eddefe313e7edb3 164 SMART SM00359 88 162 7.9E-13 T 23-10-2018 IPR002478 PUA domain GO:0003723 Mlab_1348 09e4d5c42ae3c6708eddefe313e7edb3 164 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 17 86 9.7E-28 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 Mlab_1348 09e4d5c42ae3c6708eddefe313e7edb3 164 Gene3D G3DSA:3.10.450.90 10 84 2.8E-25 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 Mlab_1348 09e4d5c42ae3c6708eddefe313e7edb3 164 SUPERFAMILY SSF88802 11 84 1.44E-19 T 23-10-2018 Mlab_1348 09e4d5c42ae3c6708eddefe313e7edb3 164 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 82 158 3.7E-14 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 Mlab_1348 09e4d5c42ae3c6708eddefe313e7edb3 164 Gene3D G3DSA:2.30.130.10 85 161 3.3E-30 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 Mlab_1348 09e4d5c42ae3c6708eddefe313e7edb3 164 SUPERFAMILY SSF88697 87 159 1.1E-19 T 23-10-2018 IPR015947 PUA-like superfamily Mlab_1348 09e4d5c42ae3c6708eddefe313e7edb3 164 Pfam PF01472 PUA domain 89 159 6.6E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 Mlab_0119 d0fd91aa6abd357df79adddeb22a56c8 235 Pfam PF08713 DNA alkylation repair enzyme 13 214 6.6E-13 T 23-10-2018 IPR014825 DNA alkylation repair enzyme Mlab_0119 d0fd91aa6abd357df79adddeb22a56c8 235 SUPERFAMILY SSF48371 16 217 9.35E-39 T 23-10-2018 IPR016024 Armadillo-type fold Mlab_0119 d0fd91aa6abd357df79adddeb22a56c8 235 Gene3D G3DSA:1.25.10.90 5 229 4.9E-14 T 23-10-2018 Mlab_1755 b3baf2898f79e9af58900351d19ff0f3 172 Pfam PF00583 Acetyltransferase (GNAT) family 60 146 8.7E-13 T 23-10-2018 IPR000182 GNAT domain Mlab_1755 b3baf2898f79e9af58900351d19ff0f3 172 Gene3D G3DSA:3.40.630.30 9 153 7.0E-27 T 23-10-2018 Mlab_1755 b3baf2898f79e9af58900351d19ff0f3 172 SUPERFAMILY SSF55729 10 169 2.92E-23 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_1482 9f3ed8f80d8ea8b868d24b67ee921faa 110 Gene3D G3DSA:1.10.8.140 30 109 3.9E-27 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 Mlab_1482 9f3ed8f80d8ea8b868d24b67ee921faa 110 PIRSF PIRSF015730 1 110 5.4E-30 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 Mlab_1482 9f3ed8f80d8ea8b868d24b67ee921faa 110 Pfam PF01984 Double-stranded DNA-binding domain 9 106 3.4E-28 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 Mlab_1482 9f3ed8f80d8ea8b868d24b67ee921faa 110 Hamap MF_00026 DNA-binding protein . 4 108 16.657 T 23-10-2018 IPR022889 DNA-binding protein, archaeal Mlab_1482 9f3ed8f80d8ea8b868d24b67ee921faa 110 SUPERFAMILY SSF46950 9 108 1.44E-29 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 Mlab_0327 4d9c513c174c4eea925f8148da27e9eb 381 Pfam PF01497 Periplasmic binding protein 117 315 3.4E-25 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain Mlab_0327 4d9c513c174c4eea925f8148da27e9eb 381 Gene3D G3DSA:3.40.50.1980 33 181 1.8E-29 T 23-10-2018 Mlab_0327 4d9c513c174c4eea925f8148da27e9eb 381 SUPERFAMILY SSF53807 36 340 3.49E-51 T 23-10-2018 Mlab_0327 4d9c513c174c4eea925f8148da27e9eb 381 Gene3D G3DSA:3.40.50.1980 183 381 3.6E-64 T 23-10-2018 Mlab_1529 f562626a0ccaf61a2860adee47c08b65 242 Pfam PF07790 Archaeal Type IV pilin, N-terminal 14 101 4.2E-13 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_0657 636c71da6cd1036dad7ef5642fa6431b 72 Pfam PF06093 Spt4/RpoE2 zinc finger 13 72 4.5E-12 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 Mlab_0657 636c71da6cd1036dad7ef5642fa6431b 72 Gene3D G3DSA:2.20.28.90 3 72 7.2E-23 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily Mlab_0657 636c71da6cd1036dad7ef5642fa6431b 72 SUPERFAMILY SSF63393 7 72 6.8E-20 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 Mlab_0657 636c71da6cd1036dad7ef5642fa6431b 72 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 14 72 27.49 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 Mlab_0657 636c71da6cd1036dad7ef5642fa6431b 72 SMART SM01389 12 72 6.2E-24 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 Mlab_0657 636c71da6cd1036dad7ef5642fa6431b 72 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 29 71 2.0E-8 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 Mlab_0433 e5841f02c60ef5d2e0075cdc6893770d 323 SUPERFAMILY SSF64182 25 311 4.97E-18 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily Mlab_0433 e5841f02c60ef5d2e0075cdc6893770d 323 Gene3D G3DSA:3.10.310.30 255 317 3.6E-8 T 23-10-2018 Mlab_0248 833955633872b1e2b9d5cf41393cb69d 70 Gene3D G3DSA:2.20.28.10 2 55 4.6E-21 T 23-10-2018 Mlab_0248 833955633872b1e2b9d5cf41393cb69d 70 PRINTS PR00163 Rubredoxin signature 33 49 4.6E-7 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 Mlab_0248 833955633872b1e2b9d5cf41393cb69d 70 PRINTS PR00163 Rubredoxin signature 3 19 4.6E-7 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 Mlab_0248 833955633872b1e2b9d5cf41393cb69d 70 SUPERFAMILY SSF57802 1 48 8.92E-20 T 23-10-2018 Mlab_0248 833955633872b1e2b9d5cf41393cb69d 70 Pfam PF00301 Rubredoxin 3 47 2.8E-20 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 Mlab_1737 9dfbc679aa3ee22bca95f42a5de9bee5 234 Pfam PF03358 NADPH-dependent FMN reductase 1 144 9.9E-22 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Mlab_1737 9dfbc679aa3ee22bca95f42a5de9bee5 234 SUPERFAMILY SSF52218 1 226 9.51E-30 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1737 9dfbc679aa3ee22bca95f42a5de9bee5 234 Gene3D G3DSA:3.40.50.360 1 229 5.2E-46 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1071 b4dcacfcd5db86453735b5aa451763d0 457 SUPERFAMILY SSF81340 12 449 5.89E-88 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 Mlab_1071 b4dcacfcd5db86453735b5aa451763d0 457 PRINTS PR00762 Chloride channel signature 387 403 3.0E-22 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Mlab_1071 b4dcacfcd5db86453735b5aa451763d0 457 PRINTS PR00762 Chloride channel signature 350 370 3.0E-22 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Mlab_1071 b4dcacfcd5db86453735b5aa451763d0 457 PRINTS PR00762 Chloride channel signature 405 424 3.0E-22 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Mlab_1071 b4dcacfcd5db86453735b5aa451763d0 457 PRINTS PR00762 Chloride channel signature 172 191 3.0E-22 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Mlab_1071 b4dcacfcd5db86453735b5aa451763d0 457 PRINTS PR00762 Chloride channel signature 121 140 3.0E-22 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Mlab_1071 b4dcacfcd5db86453735b5aa451763d0 457 Gene3D G3DSA:1.10.3080.10 5 452 1.3E-90 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 Mlab_1071 b4dcacfcd5db86453735b5aa451763d0 457 Pfam PF00654 Voltage gated chloride channel 80 436 3.9E-81 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Mlab_1209 a7e661e74f5e822ea90a6dc2af5e58ac 196 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 4 179 7.1E-43 T 23-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Mlab_1209 a7e661e74f5e822ea90a6dc2af5e58ac 196 Gene3D G3DSA:3.40.50.10420 1 187 1.4E-50 T 23-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily Mlab_1209 a7e661e74f5e822ea90a6dc2af5e58ac 196 SUPERFAMILY SSF100950 3 187 5.16E-47 T 23-10-2018 IPR037171 NagB/RpiA transferase-like Mlab_1209 a7e661e74f5e822ea90a6dc2af5e58ac 196 PIRSF PIRSF006806 1 182 5.2E-39 T 23-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Mlab_1209 a7e661e74f5e822ea90a6dc2af5e58ac 196 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 4 179 3.3E-36 T 23-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Mlab_0044 aebfe89ae0d189ca52ced4720949811a 307 Pfam PF00005 ABC transporter 25 180 5.5E-24 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0044 aebfe89ae0d189ca52ced4720949811a 307 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 301 4.9E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Mlab_0044 aebfe89ae0d189ca52ced4720949811a 307 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 291 1.7E-15 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Mlab_0044 aebfe89ae0d189ca52ced4720949811a 307 SMART SM00382 33 229 1.7E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0044 aebfe89ae0d189ca52ced4720949811a 307 Gene3D G3DSA:3.40.50.300 1 306 7.6E-81 T 23-10-2018 Mlab_0044 aebfe89ae0d189ca52ced4720949811a 307 SUPERFAMILY SSF52540 4 251 5.55E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0044 aebfe89ae0d189ca52ced4720949811a 307 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Mlab_1519 1af0f3fe365b433eb52e00161729f0e5 129 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 114 14.438 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 Mlab_1519 1af0f3fe365b433eb52e00161729f0e5 129 SMART SM01405 4 125 3.4E-58 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1519 1af0f3fe365b433eb52e00161729f0e5 129 Pfam PF01092 Ribosomal protein S6e 4 123 6.0E-37 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0065 9dc179dab9bdc819c0d3ded167312cd4 754 TIGRFAM TIGR04126 PGF_CTERM: PGF-CTERM archaeal protein-sorting signal 727 754 3.2E-6 T 23-10-2018 IPR026371 PGF-CTERM archaeal protein-sorting signal Mlab_0217 60923f5038c29654f4d9f7b13dea94ce 200 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 115 121 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Mlab_0217 60923f5038c29654f4d9f7b13dea94ce 200 SUPERFAMILY SSF53335 6 159 9.1E-33 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0217 60923f5038c29654f4d9f7b13dea94ce 200 Pfam PF05175 Methyltransferase small domain 44 129 2.1E-16 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 Mlab_0217 60923f5038c29654f4d9f7b13dea94ce 200 Gene3D G3DSA:3.40.50.150 1 200 2.4E-54 T 23-10-2018 Mlab_0437 f3b888f5b2e160b25d324478761d38bb 143 Gene3D G3DSA:3.40.50.150 9 142 1.1E-20 T 23-10-2018 Mlab_0437 f3b888f5b2e160b25d324478761d38bb 143 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 27 118 5.0E-15 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 Mlab_0437 f3b888f5b2e160b25d324478761d38bb 143 Pfam PF03686 Uncharacterised protein family (UPF0146) 22 118 1.3E-19 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 Mlab_0437 f3b888f5b2e160b25d324478761d38bb 143 Hamap MF_00341 UPF0146 protein . 16 140 20.729 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 Mlab_0287 7b3ce99901a16f11afdc8658fa0800c9 206 SMART SM01397 6 197 2.0E-72 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0287 7b3ce99901a16f11afdc8658fa0800c9 206 Pfam PF01015 Ribosomal S3Ae family 8 194 7.9E-50 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0287 7b3ce99901a16f11afdc8658fa0800c9 206 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 6 197 25.545 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Mlab_1274 c03fcb5d739da0d65acbdf6ed021255a 334 SUPERFAMILY SSF48239 11 176 2.28E-18 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Mlab_1274 c03fcb5d739da0d65acbdf6ed021255a 334 Gene3D G3DSA:1.50.10.20 2 191 3.8E-18 T 23-10-2018 Mlab_1125 c51f1f2b99091fc4770e7ed5746c1a13 127 SUPERFAMILY SSF49764 45 121 4.97E-8 T 23-10-2018 IPR008978 HSP20-like chaperone Mlab_1125 c51f1f2b99091fc4770e7ed5746c1a13 127 Gene3D G3DSA:2.60.40.790 42 122 7.4E-7 T 23-10-2018 IPR008978 HSP20-like chaperone Mlab_1424 a5ebe3ca29bef00754f0bee62d909270 361 Gene3D G3DSA:3.40.50.720 3 193 4.9E-48 T 23-10-2018 Mlab_1424 a5ebe3ca29bef00754f0bee62d909270 361 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 6 356 8.5E-146 T 23-10-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 Mlab_1424 a5ebe3ca29bef00754f0bee62d909270 361 Gene3D G3DSA:3.90.25.10 194 359 9.0E-62 T 23-10-2018 Mlab_1424 a5ebe3ca29bef00754f0bee62d909270 361 Pfam PF16363 GDP-mannose 4,6 dehydratase 12 331 4.2E-40 T 23-10-2018 IPR016040 NAD(P)-binding domain Mlab_1424 a5ebe3ca29bef00754f0bee62d909270 361 SUPERFAMILY SSF51735 8 339 5.07E-62 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0702 de34a1a32ebef6ab70da247697f6574b 564 Pfam PF02743 Cache domain 124 255 8.2E-12 T 23-10-2018 IPR033479 Double Cache domain 1 Mlab_0702 de34a1a32ebef6ab70da247697f6574b 564 Gene3D G3DSA:3.30.450.20 291 425 1.8E-21 T 23-10-2018 Mlab_0702 de34a1a32ebef6ab70da247697f6574b 564 Gene3D G3DSA:3.30.450.20 426 543 9.0E-7 T 23-10-2018 Mlab_0702 de34a1a32ebef6ab70da247697f6574b 564 SMART SM01049 292 376 2.9E-14 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0702 de34a1a32ebef6ab70da247697f6574b 564 Pfam PF17200 Single Cache domain 2 318 424 1.2E-16 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_1439 a972b4a6dc3a5ca0cade9a98fb0b1d97 540 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 65 220 5.0E-21 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like Mlab_1439 a972b4a6dc3a5ca0cade9a98fb0b1d97 540 TIGRFAM TIGR03663 TIGR03663: TIGR03663 family protein 16 457 3.1E-166 T 23-10-2018 IPR019962 Conserved hypothetical protein CHP03663 Mlab_0477 5ce3650b8cdd4235be6beb2dec5fda65 147 SUPERFAMILY SSF54534 3 140 2.95E-38 T 23-10-2018 Mlab_0477 5ce3650b8cdd4235be6beb2dec5fda65 147 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 137 6.7E-23 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Mlab_0477 5ce3650b8cdd4235be6beb2dec5fda65 147 Gene3D G3DSA:3.10.50.40 1 147 7.3E-49 T 23-10-2018 Mlab_1279 1bba29a18f1c49f62faec60bfe624d7f 280 Pfam PF01261 Xylose isomerase-like TIM barrel 20 204 7.8E-14 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Mlab_1279 1bba29a18f1c49f62faec60bfe624d7f 280 Gene3D G3DSA:3.20.20.150 1 250 3.9E-36 T 23-10-2018 Mlab_1279 1bba29a18f1c49f62faec60bfe624d7f 280 SUPERFAMILY SSF51658 2 243 5.63E-34 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily Mlab_0871 33f6521d64b3eba39d962a626af8ae08 241 Pfam PF01261 Xylose isomerase-like TIM barrel 50 201 1.4E-10 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Mlab_0871 33f6521d64b3eba39d962a626af8ae08 241 SUPERFAMILY SSF51658 2 225 7.46E-32 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily Mlab_0871 33f6521d64b3eba39d962a626af8ae08 241 Gene3D G3DSA:3.20.20.150 1 238 1.8E-40 T 23-10-2018 Mlab_0339 4437ab824cad209addf297f2df932223 111 Gene3D G3DSA:3.30.420.130 1 111 9.7E-26 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Mlab_0339 4437ab824cad209addf297f2df932223 111 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 103 5.8E-20 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis Mlab_0339 4437ab824cad209addf297f2df932223 111 SUPERFAMILY SSF53146 1 109 9.81E-25 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Mlab_1528 98a173d346d877e03c4d450f64b0af8c 200 Pfam PF09339 IclR helix-turn-helix domain 24 63 1.2E-5 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Mlab_1528 98a173d346d877e03c4d450f64b0af8c 200 SUPERFAMILY SSF46785 21 87 8.29E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1528 98a173d346d877e03c4d450f64b0af8c 200 Gene3D G3DSA:1.10.10.10 16 80 5.5E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0097 178151fedde67f54f7efad7443ded5c0 174 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 151 172 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0097 178151fedde67f54f7efad7443ded5c0 174 Gene3D G3DSA:3.90.930.12 81 174 2.1E-37 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0097 178151fedde67f54f7efad7443ded5c0 174 Pfam PF00347 Ribosomal protein L6 8 80 4.2E-13 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0097 178151fedde67f54f7efad7443ded5c0 174 Pfam PF00347 Ribosomal protein L6 92 166 2.0E-11 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0097 178151fedde67f54f7efad7443ded5c0 174 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 1 173 33.128 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 Mlab_0097 178151fedde67f54f7efad7443ded5c0 174 SUPERFAMILY SSF56053 81 171 1.73E-28 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0097 178151fedde67f54f7efad7443ded5c0 174 PIRSF PIRSF002162 1 174 3.6E-32 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0097 178151fedde67f54f7efad7443ded5c0 174 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 5 171 1.8E-72 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 Mlab_0097 178151fedde67f54f7efad7443ded5c0 174 Gene3D G3DSA:3.90.930.12 1 80 1.0E-23 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0097 178151fedde67f54f7efad7443ded5c0 174 SUPERFAMILY SSF56053 3 80 1.01E-16 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_1151 94e4316768de5f9740b57bffddb606fe 333 SUPERFAMILY SSF53807 37 315 7.46E-51 T 23-10-2018 Mlab_1151 94e4316768de5f9740b57bffddb606fe 333 Pfam PF01497 Periplasmic binding protein 51 280 1.2E-30 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain Mlab_1151 94e4316768de5f9740b57bffddb606fe 333 Gene3D G3DSA:3.40.50.1980 23 328 6.3E-63 T 23-10-2018 Mlab_1752 dd3b7c88c9e7dd1a1ae7bdd33695864f 164 PIRSF PIRSF022062 1 164 1.5E-30 T 23-10-2018 IPR016799 Uncharacterised conserved protein UCP022062 Mlab_1752 dd3b7c88c9e7dd1a1ae7bdd33695864f 164 SUPERFAMILY SSF143870 2 151 1.28E-25 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 Mlab_1752 dd3b7c88c9e7dd1a1ae7bdd33695864f 164 Gene3D G3DSA:3.30.2380.10 11 152 2.9E-18 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 Mlab_1752 dd3b7c88c9e7dd1a1ae7bdd33695864f 164 Pfam PF08617 Kinase binding protein CGI-121 33 159 3.2E-8 T 23-10-2018 IPR013926 CGI121/TPRKB Reactome: R-HSA-6782315 Mlab_1212 3afab674c0da395020263be944ccaf45 219 Gene3D G3DSA:3.40.50.1000 7 206 1.9E-66 T 23-10-2018 IPR023214 HAD superfamily Mlab_1212 3afab674c0da395020263be944ccaf45 219 SUPERFAMILY SSF56784 1 215 6.27E-61 T 23-10-2018 IPR036412 HAD-like superfamily Mlab_1212 3afab674c0da395020263be944ccaf45 219 Gene3D G3DSA:1.10.150.240 18 84 1.9E-66 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Mlab_1212 3afab674c0da395020263be944ccaf45 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 186 1.7E-31 T 23-10-2018 Mlab_1212 3afab674c0da395020263be944ccaf45 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 71 180 7.2E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Mlab_0974 d87ef2b2762b831fa6969c4c22d28cb3 1278 SUPERFAMILY SSF48371 559 1108 4.48E-5 T 23-10-2018 IPR016024 Armadillo-type fold Mlab_0974 d87ef2b2762b831fa6969c4c22d28cb3 1278 SUPERFAMILY SSF52540 207 388 5.74E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0260 5a339e4af85bc4b552f319ec237107a7 266 Pfam PF02361 Cobalt transport protein 15 227 2.7E-27 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component Mlab_0134 703fc16c6cbfd22803735fcc5aa63065 187 SMART SM00382 24 173 0.0083 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0134 703fc16c6cbfd22803735fcc5aa63065 187 SUPERFAMILY SSF52540 27 173 1.24E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0134 703fc16c6cbfd22803735fcc5aa63065 187 Pfam PF00005 ABC transporter 102 138 4.2E-6 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0134 703fc16c6cbfd22803735fcc5aa63065 187 Gene3D G3DSA:3.40.50.300 21 184 2.1E-23 T 23-10-2018 Mlab_1003 bf5de1d9637f576f743911158a106904 235 Gene3D G3DSA:3.40.1160.10 2 226 1.7E-51 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_1003 bf5de1d9637f576f743911158a106904 235 PIRSF PIRSF005650 1 232 2.6E-53 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 Mlab_1003 bf5de1d9637f576f743911158a106904 235 SUPERFAMILY SSF53633 3 225 2.36E-43 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_1003 bf5de1d9637f576f743911158a106904 235 Hamap MF_01220_A Uridylate kinase [pyrH]. 2 227 32.377 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 Mlab_1003 bf5de1d9637f576f743911158a106904 235 Pfam PF00696 Amino acid kinase family 3 204 2.0E-24 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Mlab_1003 bf5de1d9637f576f743911158a106904 235 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 4 225 7.0E-75 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 Mlab_1742 d41fe08feab0edeb6d81639bf3c523ec 211 Gene3D G3DSA:3.40.50.720 1 211 8.5E-7 T 23-10-2018 Mlab_1742 d41fe08feab0edeb6d81639bf3c523ec 211 Pfam PF00899 ThiF family 6 147 5.5E-6 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 Mlab_1742 d41fe08feab0edeb6d81639bf3c523ec 211 PIRSF PIRSF006529 1 211 4.9E-89 T 23-10-2018 IPR012028 Uncharacterised conserved protein UCP006529, dinucleotide-utilising ThiF/HesA Mlab_1742 d41fe08feab0edeb6d81639bf3c523ec 211 SUPERFAMILY SSF69572 3 138 1.06E-6 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 Mlab_0961 d3de2ddee62b2f26d152f5b9dc6feb48 146 SUPERFAMILY SSF54862 57 139 1.95E-20 T 23-10-2018 Mlab_0961 d3de2ddee62b2f26d152f5b9dc6feb48 146 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 65 76 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0961 d3de2ddee62b2f26d152f5b9dc6feb48 146 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0961 d3de2ddee62b2f26d152f5b9dc6feb48 146 Gene3D G3DSA:3.30.70.3270 46 145 4.7E-22 T 23-10-2018 Mlab_0961 d3de2ddee62b2f26d152f5b9dc6feb48 146 Pfam PF13237 4Fe-4S dicluster domain 59 121 4.3E-12 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_1486 bc069c3ee79bb61d711539fc8faa9031 206 Gene3D G3DSA:3.40.50.170 1 206 3.5E-78 T 23-10-2018 Mlab_1486 bc069c3ee79bb61d711539fc8faa9031 206 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 23-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Mlab_1486 bc069c3ee79bb61d711539fc8faa9031 206 SUPERFAMILY SSF53328 2 198 4.45E-64 T 23-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Mlab_1486 bc069c3ee79bb61d711539fc8faa9031 206 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 191 8.2E-75 T 23-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 Mlab_1486 bc069c3ee79bb61d711539fc8faa9031 206 Pfam PF00551 Formyl transferase 2 182 2.1E-58 T 23-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Mlab_1486 bc069c3ee79bb61d711539fc8faa9031 206 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 32.882 T 23-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 Mlab_1307 ebd48f0a6b51cc4b622a08a6c9a78987 152 Hamap MF_00498 UPF0179 protein . 6 149 25.591 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 Mlab_1307 ebd48f0a6b51cc4b622a08a6c9a78987 152 Pfam PF03684 Uncharacterised protein family (UPF0179) 8 147 7.7E-45 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 Mlab_1307 ebd48f0a6b51cc4b622a08a6c9a78987 152 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 8 139 2.0E-24 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 Mlab_0453 14bf944819af65cbd26ecaf85a2e4fd4 236 Hamap MF_01079 UPF0280 protein . 1 236 36.922 T 23-10-2018 IPR037456 MA1715-like Mlab_0453 14bf944819af65cbd26ecaf85a2e4fd4 236 SUPERFAMILY SSF143631 2 224 7.59E-64 T 23-10-2018 IPR003374 ApbE-like superfamily Mlab_0453 14bf944819af65cbd26ecaf85a2e4fd4 236 PIRSF PIRSF006421 1 236 8.6E-62 T 23-10-2018 IPR007183 Uncharacterised protein family UPF0280 Mlab_0453 14bf944819af65cbd26ecaf85a2e4fd4 236 Gene3D G3DSA:3.10.520.10 3 224 1.7E-58 T 23-10-2018 Mlab_0688 1831b64b8cd31f9ab2d6a1efdcc66e25 273 Gene3D G3DSA:3.40.1160.10 6 271 1.8E-51 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_0688 1831b64b8cd31f9ab2d6a1efdcc66e25 273 SUPERFAMILY SSF53633 41 270 4.45E-29 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_0688 1831b64b8cd31f9ab2d6a1efdcc66e25 273 PIRSF PIRSF039097 1 273 6.6E-122 T 23-10-2018 IPR030669 Molybdenum storage protein subunit alpha/beta GO:0005737|GO:0030151 Mlab_0688 1831b64b8cd31f9ab2d6a1efdcc66e25 273 Pfam PF00696 Amino acid kinase family 42 250 4.2E-24 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Mlab_0582 1c2689d2350f28f17939430ad0655a1b 189 Pfam PF03729 Short repeat of unknown function (DUF308) 135 183 1.4E-5 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane Mlab_0582 1c2689d2350f28f17939430ad0655a1b 189 Pfam PF03729 Short repeat of unknown function (DUF308) 78 148 3.5E-7 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane Mlab_0582 1c2689d2350f28f17939430ad0655a1b 189 Pfam PF03729 Short repeat of unknown function (DUF308) 23 90 1.9E-9 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane Mlab_1651 93333c97b9d9e02eceb7c5abcb9fd8a5 280 TIGRFAM TIGR01920 Shik_kin_archae: shikimate kinase 8 257 4.6E-69 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Mlab_1651 93333c97b9d9e02eceb7c5abcb9fd8a5 280 SUPERFAMILY SSF54211 26 172 2.13E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_1651 93333c97b9d9e02eceb7c5abcb9fd8a5 280 Pfam PF00288 GHMP kinases N terminal domain 79 142 3.6E-8 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 Mlab_1651 93333c97b9d9e02eceb7c5abcb9fd8a5 280 Gene3D G3DSA:3.30.230.10 19 161 8.2E-21 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Mlab_1651 93333c97b9d9e02eceb7c5abcb9fd8a5 280 Hamap MF_00370 Shikimate kinase [aroK]. 1 280 94.535 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Mlab_1651 93333c97b9d9e02eceb7c5abcb9fd8a5 280 PIRSF PIRSF005758 1 277 1.5E-72 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Mlab_1220 7ae088e4bc349b39b25e347bbb6acf22 352 Gene3D G3DSA:1.10.132.50 11 344 9.2E-81 T 23-10-2018 Mlab_1220 7ae088e4bc349b39b25e347bbb6acf22 352 Pfam PF01992 ATP synthase (C/AC39) subunit 15 349 9.0E-71 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1220 7ae088e4bc349b39b25e347bbb6acf22 352 SUPERFAMILY SSF103486 11 351 9.55E-58 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1220 7ae088e4bc349b39b25e347bbb6acf22 352 Gene3D G3DSA:1.20.1690.10 194 311 9.2E-81 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1220 7ae088e4bc349b39b25e347bbb6acf22 352 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 8 351 9.8E-85 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 Mlab_1220 7ae088e4bc349b39b25e347bbb6acf22 352 Gene3D G3DSA:1.20.1690.10 89 193 9.2E-81 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1220 7ae088e4bc349b39b25e347bbb6acf22 352 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 7 352 28.098 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 Mlab_1616 adb7fec16f7ba8b02258a3cf8fbdfe18 135 SUPERFAMILY SSF55620 1 134 1.06E-32 T 23-10-2018 Mlab_1616 adb7fec16f7ba8b02258a3cf8fbdfe18 135 Gene3D G3DSA:3.30.479.10 81 135 3.2E-5 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 Mlab_1616 adb7fec16f7ba8b02258a3cf8fbdfe18 135 Gene3D G3DSA:3.30.479.10 1 80 2.9E-17 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 Mlab_1616 adb7fec16f7ba8b02258a3cf8fbdfe18 135 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 133 8.1E-32 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 Mlab_0174 1e492daec6fe8f61037d85a4e770e01f 394 Gene3D G3DSA:3.60.15.10 1 244 8.0E-78 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_0174 1e492daec6fe8f61037d85a4e770e01f 394 SUPERFAMILY SSF52218 248 391 3.38E-28 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0174 1e492daec6fe8f61037d85a4e770e01f 394 SMART SM00849 34 225 9.4E-23 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0174 1e492daec6fe8f61037d85a4e770e01f 394 PIRSF PIRSF005243 1 394 5.4E-112 T 23-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 Mlab_0174 1e492daec6fe8f61037d85a4e770e01f 394 Gene3D G3DSA:3.40.50.360 247 393 7.8E-23 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0174 1e492daec6fe8f61037d85a4e770e01f 394 Pfam PF00258 Flavodoxin 253 371 1.4E-6 T 23-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 Mlab_0174 1e492daec6fe8f61037d85a4e770e01f 394 SUPERFAMILY SSF56281 4 280 3.41E-44 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Mlab_0174 1e492daec6fe8f61037d85a4e770e01f 394 Pfam PF00753 Metallo-beta-lactamase superfamily 35 215 3.9E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase Mlab_0536 39be647d3486ab82e40bd1a54d94c992 224 SUPERFAMILY SSF158702 125 182 1.96E-7 T 23-10-2018 Mlab_0536 39be647d3486ab82e40bd1a54d94c992 224 Pfam PF14229 Domain of unknown function (DUF4332) 99 196 1.3E-12 T 23-10-2018 IPR025567 Domain of unknown function DUF4332 KEGG: 00970+6.1.1.6 Mlab_0536 39be647d3486ab82e40bd1a54d94c992 224 Gene3D G3DSA:1.10.150.20 149 194 4.5E-7 T 23-10-2018 Mlab_0704 cd19d7bad3a57545568591a9b284dc5e 553 SMART SM01049 289 369 6.1E-12 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0704 cd19d7bad3a57545568591a9b284dc5e 553 SMART SM01049 429 505 0.13 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0704 cd19d7bad3a57545568591a9b284dc5e 553 Pfam PF17200 Single Cache domain 2 305 416 1.2E-17 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0704 cd19d7bad3a57545568591a9b284dc5e 553 Gene3D G3DSA:3.30.450.20 423 548 9.6E-12 T 23-10-2018 Mlab_0704 cd19d7bad3a57545568591a9b284dc5e 553 Gene3D G3DSA:3.30.450.20 284 422 2.4E-32 T 23-10-2018 Mlab_0841 0649c7b4d01b467c86605d0dad30a953 608 Pfam PF12161 HsdM N-terminal domain 12 148 2.6E-21 T 23-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain Mlab_0841 0649c7b4d01b467c86605d0dad30a953 608 SUPERFAMILY SSF53335 11 606 2.53E-111 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0841 0649c7b4d01b467c86605d0dad30a953 608 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 197 213 8.9E-11 T 23-10-2018 Mlab_0841 0649c7b4d01b467c86605d0dad30a953 608 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 228 242 8.9E-11 T 23-10-2018 Mlab_0841 0649c7b4d01b467c86605d0dad30a953 608 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 306 318 8.9E-11 T 23-10-2018 Mlab_0841 0649c7b4d01b467c86605d0dad30a953 608 Pfam PF02384 N-6 DNA Methylase 174 494 3.3E-52 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 Mlab_0841 0649c7b4d01b467c86605d0dad30a953 608 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 309 315 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Mlab_0841 0649c7b4d01b467c86605d0dad30a953 608 Gene3D G3DSA:3.40.50.150 175 504 1.1E-85 T 23-10-2018 Mlab_0705 435880386ee8955e453f1c162b78d6da 296 Pfam PF04071 Cysteine-rich small domain 210 290 4.5E-30 T 23-10-2018 IPR007212 Cysteine-rich small domain Mlab_0705 435880386ee8955e453f1c162b78d6da 296 Pfam PF01955 Adenosylcobinamide amidohydrolase 18 178 1.6E-35 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ Mlab_1438 1a2bb71fadca2cc51e779d2f0770c7cf 1572 SUPERFAMILY SSF52980 1255 1352 1.02E-12 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Mlab_1438 1a2bb71fadca2cc51e779d2f0770c7cf 1572 SUPERFAMILY SSF52540 291 1232 1.61E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1438 1a2bb71fadca2cc51e779d2f0770c7cf 1572 Pfam PF13087 AAA domain 1014 1205 5.3E-13 T 23-10-2018 Mlab_1438 1a2bb71fadca2cc51e779d2f0770c7cf 1572 Pfam PF13086 AAA domain 944 987 2.1E-6 T 23-10-2018 Mlab_1438 1a2bb71fadca2cc51e779d2f0770c7cf 1572 Gene3D G3DSA:3.40.50.300 241 472 1.6E-15 T 23-10-2018 Mlab_1438 1a2bb71fadca2cc51e779d2f0770c7cf 1572 Gene3D G3DSA:3.40.50.300 846 1018 4.0E-13 T 23-10-2018 Mlab_1438 1a2bb71fadca2cc51e779d2f0770c7cf 1572 Pfam PF13195 Protein of unknown function (DUF4011) 14 181 9.3E-41 T 23-10-2018 IPR025103 Protein of unknown function DUF4011 Mlab_1438 1a2bb71fadca2cc51e779d2f0770c7cf 1572 Gene3D G3DSA:3.40.960.10 1254 1354 1.7E-10 T 23-10-2018 Mlab_1438 1a2bb71fadca2cc51e779d2f0770c7cf 1572 Pfam PF11784 Protein of unknown function (DUF3320) 1412 1458 1.0E-8 T 23-10-2018 IPR021754 Protein of unknown function DUF3320 Mlab_1438 1a2bb71fadca2cc51e779d2f0770c7cf 1572 Gene3D G3DSA:3.40.50.300 1031 1243 8.0E-27 T 23-10-2018 Mlab_1438 1a2bb71fadca2cc51e779d2f0770c7cf 1572 SMART SM00952 1295 1352 0.001 T 23-10-2018 IPR013584 RAP domain Mlab_0550 9e498aafeff04926f91bc5b42177e546 193 TIGRFAM TIGR03291 methan_mark_17: putative methanogenesis marker protein 17 9 180 2.7E-48 T 23-10-2018 IPR016762 Uncharacterised conserved protein UCP019464, methanogenesis Mlab_0550 9e498aafeff04926f91bc5b42177e546 193 Pfam PF09886 Uncharacterized protein conserved in archaea (DUF2113) 7 187 2.8E-61 T 23-10-2018 IPR016762 Uncharacterised conserved protein UCP019464, methanogenesis Mlab_0890 0945b57ed85020eb5122ecc6cd773ca9 337 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 42 320 6.1E-47 T 23-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system Mlab_0890 0945b57ed85020eb5122ecc6cd773ca9 337 Gene3D G3DSA:3.10.450.620 41 112 3.6E-6 T 23-10-2018 Mlab_1422 9cc44effe99b32eaaed1834ba34e0bb5 490 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 332 467 2.7E-23 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain Mlab_1422 9cc44effe99b32eaaed1834ba34e0bb5 490 Pfam PF13440 Polysaccharide biosynthesis protein 43 325 1.3E-18 T 23-10-2018 Mlab_1291 5cbd9f1571074956107751026c59d30a 402 SUPERFAMILY SSF69864 177 400 8.11E-83 T 23-10-2018 Mlab_1291 5cbd9f1571074956107751026c59d30a 402 Gene3D G3DSA:3.90.1260.10 180 402 1.3E-81 T 23-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Mlab_1291 5cbd9f1571074956107751026c59d30a 402 Pfam PF00764 Arginosuccinate synthase 14 395 4.8E-162 T 23-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Mlab_1291 5cbd9f1571074956107751026c59d30a 402 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 124 135 - T 23-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Mlab_1291 5cbd9f1571074956107751026c59d30a 402 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 395 9.3E-151 T 23-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Mlab_1291 5cbd9f1571074956107751026c59d30a 402 SUPERFAMILY SSF52402 11 210 5.82E-38 T 23-10-2018 Mlab_1291 5cbd9f1571074956107751026c59d30a 402 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 16 24 - T 23-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Mlab_1291 5cbd9f1571074956107751026c59d30a 402 Hamap MF_00005 Argininosuccinate synthase [argG]. 10 401 47.502 T 23-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Mlab_1291 5cbd9f1571074956107751026c59d30a 402 Gene3D G3DSA:3.40.50.620 2 179 3.8E-51 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_1339 3a2604d980120d9ac39ff0bdecd8f7b9 94 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 4 78 23.293 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1339 3a2604d980120d9ac39ff0bdecd8f7b9 94 SUPERFAMILY SSF57829 17 87 1.28E-27 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Mlab_1339 3a2604d980120d9ac39ff0bdecd8f7b9 94 Gene3D G3DSA:2.20.25.30 16 93 1.4E-28 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1339 3a2604d980120d9ac39ff0bdecd8f7b9 94 Pfam PF01780 Ribosomal L37ae protein family 11 91 1.8E-31 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Mlab_1706 5637dafcf0da64606c31a73c24054669 303 Pfam PF11288 Protein of unknown function (DUF3089) 25 214 3.0E-57 T 23-10-2018 IPR021440 Protein of unknown function DUF3089 Mlab_1706 5637dafcf0da64606c31a73c24054669 303 SUPERFAMILY SSF53474 70 170 6.55E-7 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold Mlab_1706 5637dafcf0da64606c31a73c24054669 303 SUPERFAMILY SSF53474 97 250 2.6E-6 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold Mlab_0628 00846cc6c0bcee098dda7da4143b2dcd 170 Gene3D G3DSA:3.40.1160.10 1 131 7.0E-11 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_0628 00846cc6c0bcee098dda7da4143b2dcd 170 SUPERFAMILY SSF53633 3 164 7.72E-9 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Mlab_0114 76ef87edcd9499db47db99a907dbe15e 235 SUPERFAMILY SSF141571 38 229 1.41E-35 T 23-10-2018 Mlab_0114 76ef87edcd9499db47db99a907dbe15e 235 Gene3D G3DSA:2.160.20.100 12 136 5.4E-18 T 23-10-2018 Mlab_0114 76ef87edcd9499db47db99a907dbe15e 235 Gene3D G3DSA:2.160.20.80 142 233 1.0E-23 T 23-10-2018 Mlab_0114 76ef87edcd9499db47db99a907dbe15e 235 Pfam PF00805 Pentapeptide repeats (8 copies) 80 109 1.4E-6 T 23-10-2018 IPR001646 Pentapeptide repeat Mlab_0114 76ef87edcd9499db47db99a907dbe15e 235 Pfam PF00805 Pentapeptide repeats (8 copies) 189 225 2.1E-11 T 23-10-2018 IPR001646 Pentapeptide repeat Mlab_0614 0bb419af69f9b468dc2cebb04d5e27bf 181 Gene3D G3DSA:3.40.630.30 6 169 1.0E-26 T 23-10-2018 Mlab_0614 0bb419af69f9b468dc2cebb04d5e27bf 181 SUPERFAMILY SSF55729 7 167 1.41E-27 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_0614 0bb419af69f9b468dc2cebb04d5e27bf 181 Pfam PF00583 Acetyltransferase (GNAT) family 53 143 7.1E-15 T 23-10-2018 IPR000182 GNAT domain Mlab_1040 ecee1dba0b3c6d21aa1acba2d4270e2b 408 SUPERFAMILY SSF53807 14 394 4.58E-28 T 23-10-2018 Mlab_1040 ecee1dba0b3c6d21aa1acba2d4270e2b 408 Gene3D G3DSA:3.40.50.1980 151 251 2.3E-8 T 23-10-2018 Mlab_1040 ecee1dba0b3c6d21aa1acba2d4270e2b 408 Gene3D G3DSA:3.40.50.1980 7 123 1.5E-7 T 23-10-2018 Mlab_1040 ecee1dba0b3c6d21aa1acba2d4270e2b 408 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 18 371 1.8E-15 T 23-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 Mlab_1276 807587247cef3ae7e53522526aafa7cd 347 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 13 325 7.7E-46 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD Mlab_1276 807587247cef3ae7e53522526aafa7cd 347 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 15 339 2.3E-57 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD Mlab_0765 ce95cd436024514945ee0bc0fee74519 223 SUPERFAMILY SSF51735 1 218 1.87E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily Mlab_0765 ce95cd436024514945ee0bc0fee74519 223 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 105 2.2E-15 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Mlab_0765 ce95cd436024514945ee0bc0fee74519 223 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 1 221 1.4E-52 T 23-10-2018 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 Mlab_0765 ce95cd436024514945ee0bc0fee74519 223 Gene3D G3DSA:3.40.50.720 1 223 3.4E-44 T 23-10-2018 Mlab_0103 69d8c5d25e7756f019865ca6777192af 141 Gene3D G3DSA:3.100.10.10 60 141 3.1E-18 T 23-10-2018 Mlab_0103 69d8c5d25e7756f019865ca6777192af 141 SUPERFAMILY SSF52080 4 139 7.19E-26 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily Mlab_0103 69d8c5d25e7756f019865ca6777192af 141 Gene3D G3DSA:4.10.990.10 3 59 1.4E-17 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal Mlab_0103 69d8c5d25e7756f019865ca6777192af 141 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 138 1.1E-17 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P Mlab_0103 69d8c5d25e7756f019865ca6777192af 141 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 140 12.68 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 Mlab_0103 69d8c5d25e7756f019865ca6777192af 141 ProSitePatterns PS00475 Ribosomal protein L15 signature. 104 134 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Mlab_0920 9cdeb43b2d8c12568e732d6e9eff061f 245 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 66 240 1.0E-52 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase Mlab_0920 9cdeb43b2d8c12568e732d6e9eff061f 245 Gene3D G3DSA:3.40.50.12640 1 245 1.3E-92 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily Mlab_0920 9cdeb43b2d8c12568e732d6e9eff061f 245 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 66 236 3.2E-62 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase Mlab_0832 cb2b342fc86b5f103b5e173fd978a349 273 Pfam PF01026 TatD related DNase 8 189 1.2E-15 T 23-10-2018 IPR001130 TatD family GO:0016788 Mlab_0832 cb2b342fc86b5f103b5e173fd978a349 273 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 103 272 3.0E-48 T 23-10-2018 Mlab_0832 cb2b342fc86b5f103b5e173fd978a349 273 PIRSF PIRSF004961 1 272 3.9E-79 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 Mlab_0832 cb2b342fc86b5f103b5e173fd978a349 273 SUPERFAMILY SSF51556 5 269 6.81E-24 T 23-10-2018 IPR032466 Metal-dependent hydrolase Mlab_0832 cb2b342fc86b5f103b5e173fd978a349 273 Gene3D G3DSA:3.20.20.140 6 271 1.3E-10 T 23-10-2018 Mlab_0662 4efef884fd49b2ca386ad260177e3bbb 868 Gene3D G3DSA:2.60.40.3390 792 868 1.8E-11 T 23-10-2018 Mlab_0662 4efef884fd49b2ca386ad260177e3bbb 868 Gene3D G3DSA:3.40.50.12610 523 692 9.4E-47 T 23-10-2018 Mlab_0662 4efef884fd49b2ca386ad260177e3bbb 868 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 49 578 8.9E-24 T 23-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 Mlab_0662 4efef884fd49b2ca386ad260177e3bbb 868 TIGRFAM TIGR04154 archaeo_STT3: oligosaccharyl transferase, archaeosortase A system-associated 20 864 2.7E-258 T 23-10-2018 IPR026410 Oligosaccharyl transferase, archaeal MetaCyc: PWY-7658|MetaCyc: PWY-7661 Mlab_0374 c9d37ef1e07b9ec15424de68465fef6d 209 SUPERFAMILY SSF53448 5 193 9.69E-27 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0374 c9d37ef1e07b9ec15424de68465fef6d 209 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 3 196 19.45 T 23-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 Mlab_0374 c9d37ef1e07b9ec15424de68465fef6d 209 Pfam PF12804 MobA-like NTP transferase domain 7 148 9.1E-28 T 23-10-2018 IPR025877 MobA-like NTP transferase Mlab_0374 c9d37ef1e07b9ec15424de68465fef6d 209 Gene3D G3DSA:3.90.550.10 6 205 6.1E-39 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0231 74e22808e2c2318e2ea29d4b4cf7f8e0 375 SUPERFAMILY SSF52518 215 323 8.83E-8 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_0231 74e22808e2c2318e2ea29d4b4cf7f8e0 375 SUPERFAMILY SSF52518 8 169 4.03E-19 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold Mlab_0231 74e22808e2c2318e2ea29d4b4cf7f8e0 375 Gene3D G3DSA:3.40.50.970 1 165 2.1E-19 T 23-10-2018 Mlab_0231 74e22808e2c2318e2ea29d4b4cf7f8e0 375 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 260 320 1.2E-5 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Mlab_0411 9d6d02f07df5bc61764fce376969d37a 202 Pfam PF00117 Glutamine amidotransferase class-I 8 198 2.0E-19 T 23-10-2018 IPR017926 Glutamine amidotransferase Mlab_0411 9d6d02f07df5bc61764fce376969d37a 202 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 5 200 35.581 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Mlab_0411 9d6d02f07df5bc61764fce376969d37a 202 Gene3D G3DSA:3.40.50.880 2 202 5.7E-73 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0411 9d6d02f07df5bc61764fce376969d37a 202 SUPERFAMILY SSF52317 6 201 9.6E-54 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0411 9d6d02f07df5bc61764fce376969d37a 202 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 6 200 7.6E-66 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Mlab_0411 9d6d02f07df5bc61764fce376969d37a 202 PIRSF PIRSF000495 4 202 1.0E-68 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Mlab_1690 1cd9ec88c438bf83efaa946475aec9aa 118 SUPERFAMILY SSF51182 11 103 1.38E-18 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily Mlab_1690 1cd9ec88c438bf83efaa946475aec9aa 118 Gene3D G3DSA:2.60.120.10 13 111 2.2E-19 T 23-10-2018 IPR014710 RmlC-like jelly roll fold Mlab_1690 1cd9ec88c438bf83efaa946475aec9aa 118 Pfam PF07883 Cupin domain 35 102 6.8E-13 T 23-10-2018 IPR013096 Cupin 2, conserved barrel Mlab_0584 0b6f3c59a050d60fb8111f046d9e79c5 387 Hamap MF_02096 DNA repair protein. 1 387 33.753 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 Mlab_0584 0b6f3c59a050d60fb8111f046d9e79c5 387 Pfam PF04894 Archaeal Nre, N-terminal 13 269 1.1E-87 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal Mlab_0584 0b6f3c59a050d60fb8111f046d9e79c5 387 Pfam PF04895 Archaeal Nre, C-terminal 284 387 5.6E-32 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal Mlab_0324 9ee8f22e0005e4590157443d75bc7bcf 120 Gene3D G3DSA:1.10.10.10 1 77 3.2E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0324 9ee8f22e0005e4590157443d75bc7bcf 120 Pfam PF01047 MarR family 25 62 8.6E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Mlab_0324 9ee8f22e0005e4590157443d75bc7bcf 120 SUPERFAMILY SSF46785 4 68 1.1E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1019 0419dd9f1da8d44f813a3e8def35c5f0 168 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 3 165 1.4E-71 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 Mlab_1019 0419dd9f1da8d44f813a3e8def35c5f0 168 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 61 1.1E-14 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Mlab_1019 0419dd9f1da8d44f813a3e8def35c5f0 168 SUPERFAMILY SSF52374 2 162 9.7E-33 T 23-10-2018 Mlab_1019 0419dd9f1da8d44f813a3e8def35c5f0 168 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 168 84.061 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 Mlab_1019 0419dd9f1da8d44f813a3e8def35c5f0 168 Pfam PF01467 Cytidylyltransferase-like 5 132 1.8E-15 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Mlab_1019 0419dd9f1da8d44f813a3e8def35c5f0 168 Gene3D G3DSA:3.40.50.620 1 168 8.5E-47 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Mlab_0490 53b2fe180613bd7eef22fb052b604812 405 Gene3D G3DSA:3.30.300.340 15 286 5.9E-148 T 23-10-2018 Mlab_0490 53b2fe180613bd7eef22fb052b604812 405 Gene3D G3DSA:3.30.300.10 27 156 5.9E-148 T 23-10-2018 Mlab_0490 53b2fe180613bd7eef22fb052b604812 405 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 3 401 6.0E-169 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 Mlab_0490 53b2fe180613bd7eef22fb052b604812 405 Gene3D G3DSA:3.30.300.280 13 398 5.9E-148 T 23-10-2018 Mlab_0490 53b2fe180613bd7eef22fb052b604812 405 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 3 393 3.0E-133 T 23-10-2018 Mlab_1381 e701a7db2519e44c58ee588b81369736 200 SMART SM00418 18 103 0.0016 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Mlab_1381 e701a7db2519e44c58ee588b81369736 200 SUPERFAMILY SSF46785 15 100 5.1E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1381 e701a7db2519e44c58ee588b81369736 200 Gene3D G3DSA:1.10.10.10 10 95 2.9E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1381 e701a7db2519e44c58ee588b81369736 200 Pfam PF12840 Helix-turn-helix domain 18 75 4.6E-13 T 23-10-2018 Mlab_1452 701edf63c0a6992d14f241bfe2467664 777 Pfam PF13581 Histidine kinase-like ATPase domain 649 771 2.1E-18 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Mlab_1452 701edf63c0a6992d14f241bfe2467664 777 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 65 175 5.4E-6 T 23-10-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 Mlab_1452 701edf63c0a6992d14f241bfe2467664 777 Gene3D G3DSA:3.30.565.10 641 776 3.8E-14 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Mlab_0125 520cc1302906160f41563a8e237af92c 197 Gene3D G3DSA:3.40.1180.10 21 197 2.8E-26 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Mlab_0125 520cc1302906160f41563a8e237af92c 197 Pfam PF01255 Putative undecaprenyl diphosphate synthase 76 196 1.4E-21 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Mlab_0125 520cc1302906160f41563a8e237af92c 197 SUPERFAMILY SSF64005 97 191 3.4E-25 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Mlab_0794 dd8683d51938e268e71c7ed9261aa7b9 379 SUPERFAMILY SSF53335 5 369 7.72E-100 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0794 dd8683d51938e268e71c7ed9261aa7b9 379 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 26 369 1.3E-94 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 Mlab_0794 dd8683d51938e268e71c7ed9261aa7b9 379 Gene3D G3DSA:3.40.50.150 1 311 4.7E-87 T 23-10-2018 Mlab_0794 dd8683d51938e268e71c7ed9261aa7b9 379 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 8 369 2.8E-86 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 Mlab_0794 dd8683d51938e268e71c7ed9261aa7b9 379 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 371 39.177 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 Mlab_0794 dd8683d51938e268e71c7ed9261aa7b9 379 Gene3D G3DSA:3.30.56.70 313 371 4.7E-18 T 23-10-2018 Mlab_0223 2877d4095a608236ad5dbb4ed926864d 153 SUPERFAMILY SSF75181 2 147 4.84E-33 T 23-10-2018 IPR036608 MTH777-like superfamily Mlab_0223 2877d4095a608236ad5dbb4ed926864d 153 Pfam PF09001 Domain of unknown function (DUF1890) 5 145 1.7E-48 T 23-10-2018 IPR012033 Uncharacterised conserved protein UCP006600 Mlab_0223 2877d4095a608236ad5dbb4ed926864d 153 Gene3D G3DSA:3.40.50.10160 1 149 5.3E-48 T 23-10-2018 IPR036608 MTH777-like superfamily Mlab_1037 2937716814223c82c9cd0730cd420c6f 483 Gene3D G3DSA:3.40.640.10 4 285 7.5E-95 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Mlab_1037 2937716814223c82c9cd0730cd420c6f 483 Gene3D G3DSA:3.90.105.10 419 474 3.2E-19 T 23-10-2018 Mlab_1037 2937716814223c82c9cd0730cd420c6f 483 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 414 471 7.9E-12 T 23-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 Mlab_1037 2937716814223c82c9cd0730cd420c6f 483 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 286 8.2E-61 T 23-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 Mlab_1037 2937716814223c82c9cd0730cd420c6f 483 SUPERFAMILY SSF53383 4 386 1.71E-69 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_0583 c337245eef47a2a3bca698643d6b2828 189 Pfam PF13411 MerR HTH family regulatory protein 7 68 3.5E-5 T 23-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Mlab_0686 5a673c74cc64365bc1dd47972fd2128c 409 Pfam PF04455 LOR/SDH bifunctional enzyme conserved region 4 103 8.8E-33 T 23-10-2018 IPR007545 LOR/SDH bifunctional enzyme, conserved domain Mlab_0686 5a673c74cc64365bc1dd47972fd2128c 409 Gene3D G3DSA:3.30.70.2690 2 98 3.5E-29 T 23-10-2018 Mlab_0686 5a673c74cc64365bc1dd47972fd2128c 409 Gene3D G3DSA:3.40.50.10690 174 409 1.3E-103 T 23-10-2018 Mlab_0686 5a673c74cc64365bc1dd47972fd2128c 409 TIGRFAM TIGR00300 TIGR00300: TIGR00300 family protein 4 404 2.7E-175 T 23-10-2018 IPR005239 Conserved hypothetical protein CHP00300 Mlab_1680 37bd1b30fc097197c68600cb8436bf14 160 SUPERFAMILY SSF48371 32 121 1.38E-5 T 23-10-2018 IPR016024 Armadillo-type fold Mlab_1444 60f6fe98508a1b6cb20b5b6e8b21eaf1 336 SUPERFAMILY SSF52733 31 322 6.54E-34 T 23-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Mlab_1444 60f6fe98508a1b6cb20b5b6e8b21eaf1 336 Hamap MF_01086 UPF0284 protein . 1 336 111.13 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative Mlab_1444 60f6fe98508a1b6cb20b5b6e8b21eaf1 336 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 14 328 9.6E-80 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative Mlab_1444 60f6fe98508a1b6cb20b5b6e8b21eaf1 336 Gene3D G3DSA:3.40.50.10210 9 336 1.1E-98 T 23-10-2018 Mlab_0701 1c658f5a3e5bca8528b335fe463dd990 565 Pfam PF17200 Single Cache domain 2 332 425 2.4E-18 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0701 1c658f5a3e5bca8528b335fe463dd990 565 Gene3D G3DSA:3.30.450.20 440 557 4.5E-8 T 23-10-2018 Mlab_0701 1c658f5a3e5bca8528b335fe463dd990 565 Gene3D G3DSA:3.30.450.20 293 439 1.2E-31 T 23-10-2018 Mlab_0701 1c658f5a3e5bca8528b335fe463dd990 565 SMART SM01049 295 376 2.6E-12 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0701 1c658f5a3e5bca8528b335fe463dd990 565 SMART SM01049 440 516 0.8 T 23-10-2018 IPR033480 Single Cache domain 2 Mlab_0990 fc230e0d0726fd53f11373b3b355c4e9 506 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 32 244 1.2E-43 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Mlab_0990 fc230e0d0726fd53f11373b3b355c4e9 506 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 281 497 6.7E-48 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Mlab_0990 fc230e0d0726fd53f11373b3b355c4e9 506 Pfam PF02634 FdhD/NarQ family 36 244 1.1E-48 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Mlab_0990 fc230e0d0726fd53f11373b3b355c4e9 506 Pfam PF02634 FdhD/NarQ family 285 497 5.4E-53 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Mlab_0990 fc230e0d0726fd53f11373b3b355c4e9 506 Gene3D G3DSA:3.40.140.10 105 248 6.6E-41 T 23-10-2018 Mlab_0990 fc230e0d0726fd53f11373b3b355c4e9 506 Gene3D G3DSA:3.40.140.10 359 503 3.0E-42 T 23-10-2018 Mlab_0990 fc230e0d0726fd53f11373b3b355c4e9 506 SUPERFAMILY SSF53927 14 244 2.95E-55 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Mlab_0990 fc230e0d0726fd53f11373b3b355c4e9 506 SUPERFAMILY SSF53927 269 498 6.32E-54 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Mlab_0052 588f6cc4c36ad319099ce766c9e32757 295 Pfam PF07790 Archaeal Type IV pilin, N-terminal 10 79 1.7E-12 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_0395 f3c0c3c1f3a43620ea4b5c61de65ec82 155 SUPERFAMILY SSF52121 3 153 6.54E-64 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0395 f3c0c3c1f3a43620ea4b5c61de65ec82 155 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 149 7.6E-58 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0395 f3c0c3c1f3a43620ea4b5c61de65ec82 155 Gene3D G3DSA:3.40.50.960 1 153 3.1E-65 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0395 f3c0c3c1f3a43620ea4b5c61de65ec82 155 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 31.667 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0395 f3c0c3c1f3a43620ea4b5c61de65ec82 155 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 150 3.4E-60 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0216 0f0fec9f18a002d96f33dd49603167ce 393 SUPERFAMILY SSF103473 27 381 5.1E-47 T 23-10-2018 IPR036259 MFS transporter superfamily Mlab_0216 0f0fec9f18a002d96f33dd49603167ce 393 ProSitePatterns PS00216 Sugar transport proteins signature 1. 261 277 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Mlab_0216 0f0fec9f18a002d96f33dd49603167ce 393 Pfam PF07690 Major Facilitator Superfamily 28 334 1.2E-33 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Mlab_0216 0f0fec9f18a002d96f33dd49603167ce 393 Gene3D G3DSA:1.20.1250.20 18 191 7.3E-22 T 23-10-2018 Mlab_0216 0f0fec9f18a002d96f33dd49603167ce 393 Gene3D G3DSA:1.20.1250.20 203 383 7.4E-17 T 23-10-2018 Mlab_1224 636bb47cef9d763bd13a27f106082670 220 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 2 209 24.526 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1224 636bb47cef9d763bd13a27f106082670 220 Pfam PF01813 ATP synthase subunit D 11 203 4.9E-57 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1224 636bb47cef9d763bd13a27f106082670 220 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 4 206 1.5E-66 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_0979 9e51c10336a2d95601dd8c3f2bfaa1e2 428 Gene3D G3DSA:3.50.50.60 1 103 4.7E-14 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0979 9e51c10336a2d95601dd8c3f2bfaa1e2 428 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 151 162 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0979 9e51c10336a2d95601dd8c3f2bfaa1e2 428 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 416 2.4E-23 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Mlab_0979 9e51c10336a2d95601dd8c3f2bfaa1e2 428 Gene3D G3DSA:3.30.70.20 104 166 7.3E-6 T 23-10-2018 Mlab_0979 9e51c10336a2d95601dd8c3f2bfaa1e2 428 SUPERFAMILY SSF51905 3 417 7.77E-28 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Mlab_0979 9e51c10336a2d95601dd8c3f2bfaa1e2 428 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 104 115 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0979 9e51c10336a2d95601dd8c3f2bfaa1e2 428 Pfam PF13187 4Fe-4S dicluster domain 103 165 7.0E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Mlab_0278 1f206568120114d2960112b6513ccd66 268 SUPERFAMILY SSF54862 184 242 1.01E-13 T 23-10-2018 Mlab_0278 1f206568120114d2960112b6513ccd66 268 Gene3D G3DSA:3.30.70.20 185 267 2.7E-8 T 23-10-2018 Mlab_0278 1f206568120114d2960112b6513ccd66 268 SUPERFAMILY SSF52218 1 137 2.65E-12 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0278 1f206568120114d2960112b6513ccd66 268 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 221 232 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Mlab_0118 5a11102ca4cf8de65d7462fd040d8fc9 252 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 22 251 6.9E-63 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Mlab_0118 5a11102ca4cf8de65d7462fd040d8fc9 252 Gene3D G3DSA:3.40.1180.10 5 249 3.3E-75 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Mlab_0118 5a11102ca4cf8de65d7462fd040d8fc9 252 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 22 252 29.242 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Mlab_0118 5a11102ca4cf8de65d7462fd040d8fc9 252 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 198 215 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 Mlab_0118 5a11102ca4cf8de65d7462fd040d8fc9 252 SUPERFAMILY SSF64005 17 249 3.01E-64 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Mlab_0118 5a11102ca4cf8de65d7462fd040d8fc9 252 Pfam PF01255 Putative undecaprenyl diphosphate synthase 29 250 2.8E-62 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Mlab_0269 bc13d10d27a67bfcbaa21d06b6a52bc7 313 Gene3D G3DSA:3.30.420.190 99 308 2.4E-58 T 23-10-2018 Mlab_0269 bc13d10d27a67bfcbaa21d06b6a52bc7 313 Gene3D G3DSA:3.30.420.40 1 98 2.3E-20 T 23-10-2018 Mlab_0269 bc13d10d27a67bfcbaa21d06b6a52bc7 313 Pfam PF01968 Hydantoinase/oxoprolinase 84 263 1.4E-12 T 23-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 Mlab_0269 bc13d10d27a67bfcbaa21d06b6a52bc7 313 TIGRFAM TIGR03123 one_C_unchar_1: probable H4MPT-linked C1 transfer pathway protein 2 303 1.6E-85 T 23-10-2018 IPR002756 4-[[4-(2-aminoethyl)phenoxy]-methyl]-2-furanmethanamine-glutamate synthase KEGG: 00680+2.5.1.131|MetaCyc: PWY-5254 Mlab_1320 f59ea59d28b280d817baf78e669bfe26 230 SUPERFAMILY SSF51261 76 186 2.98E-20 T 23-10-2018 IPR011055 Duplicated hybrid motif Mlab_1320 f59ea59d28b280d817baf78e669bfe26 230 Gene3D G3DSA:2.70.70.10 30 218 8.7E-25 T 23-10-2018 IPR011055 Duplicated hybrid motif Mlab_1320 f59ea59d28b280d817baf78e669bfe26 230 Pfam PF01551 Peptidase family M23 77 187 2.0E-16 T 23-10-2018 IPR016047 Peptidase M23 Mlab_0164 8f6a298a70bea41cc05ce64c88fe76b2 339 Gene3D G3DSA:3.40.50.1980 141 250 1.3E-17 T 23-10-2018 Mlab_0164 8f6a298a70bea41cc05ce64c88fe76b2 339 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 4 303 1.3E-49 T 23-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 Mlab_0164 8f6a298a70bea41cc05ce64c88fe76b2 339 SUPERFAMILY SSF53807 2 311 1.47E-54 T 23-10-2018 Mlab_0164 8f6a298a70bea41cc05ce64c88fe76b2 339 Gene3D G3DSA:3.40.50.1980 1 140 1.4E-32 T 23-10-2018 Mlab_1286 c1114811a719dae59fd6308d0405278d 499 Pfam PF09959 Uncharacterized protein conserved in archaea (DUF2193) 3 499 5.7E-266 T 23-10-2018 IPR018694 Protein of unknown function DUF2193 Mlab_0535 4aefc0a0d4ed29a850bc52f570aed56e 160 Gene3D G3DSA:2.40.30.70 3 131 1.6E-33 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily Mlab_0535 4aefc0a0d4ed29a850bc52f570aed56e 160 SUPERFAMILY SSF118196 2 155 1.96E-43 T 23-10-2018 IPR036413 YaeB-like superfamily Mlab_0535 4aefc0a0d4ed29a850bc52f570aed56e 160 Pfam PF01980 Uncharacterised protein family UPF0066 18 125 4.1E-29 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain Mlab_0074 52950e2aa0f3a75b1cbfb8b540096e30 408 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 9 391 8.6E-63 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane Mlab_0788 6ab375a22677c47e47a80356130916e2 359 Gene3D G3DSA:3.30.230.10 65 227 1.1E-7 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Mlab_0788 6ab375a22677c47e47a80356130916e2 359 SUPERFAMILY SSF54211 45 197 5.54E-9 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Mlab_1462 a363c31680ca91545dd5210490634387 175 SUPERFAMILY SSF54060 28 119 5.3E-12 T 23-10-2018 Mlab_1462 a363c31680ca91545dd5210490634387 175 SUPERFAMILY SSF46689 125 165 1.18E-5 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Mlab_1462 a363c31680ca91545dd5210490634387 175 Gene3D G3DSA:3.90.75.20 22 123 4.3E-5 T 23-10-2018 Mlab_1096 c03239fcec2f8d4efc6effdecbacfe6d 150 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 24 144 1.6E-22 T 23-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain Mlab_1096 c03239fcec2f8d4efc6effdecbacfe6d 150 SUPERFAMILY SSF143555 13 149 2.75E-29 T 23-10-2018 Mlab_1096 c03239fcec2f8d4efc6effdecbacfe6d 150 Gene3D G3DSA:3.30.1330.130 14 146 4.6E-18 T 23-10-2018 Mlab_1495 a02e3912c2babdf6e8e0f717ddda394f 318 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 142 273 6.4E-16 T 23-10-2018 IPR006342 Methyltransferase FkbM Mlab_1495 a02e3912c2babdf6e8e0f717ddda394f 318 Pfam PF05050 Methyltransferase FkbM domain 192 281 4.2E-8 T 23-10-2018 IPR006342 Methyltransferase FkbM Mlab_1495 a02e3912c2babdf6e8e0f717ddda394f 318 Gene3D G3DSA:3.40.50.150 125 318 1.5E-48 T 23-10-2018 Mlab_1495 a02e3912c2babdf6e8e0f717ddda394f 318 SUPERFAMILY SSF53335 58 318 2.82E-59 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0397 fe219c2a0da59260abd94a3064887435 216 SUPERFAMILY SSF63380 92 196 1.19E-32 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Mlab_0397 fe219c2a0da59260abd94a3064887435 216 Gene3D G3DSA:2.40.30.20 101 204 2.3E-35 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Mlab_0397 fe219c2a0da59260abd94a3064887435 216 Pfam PF00677 Lumazine binding domain 99 183 9.7E-25 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0397 fe219c2a0da59260abd94a3064887435 216 Pfam PF00677 Lumazine binding domain 3 86 9.0E-21 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0397 fe219c2a0da59260abd94a3064887435 216 SUPERFAMILY SSF63380 1 89 4.59E-24 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Mlab_0397 fe219c2a0da59260abd94a3064887435 216 Gene3D G3DSA:2.40.30.20 1 88 4.2E-28 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Mlab_0397 fe219c2a0da59260abd94a3064887435 216 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 202 3.8E-71 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0397 fe219c2a0da59260abd94a3064887435 216 PIRSF PIRSF000498 1 211 1.0E-78 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_1363 0f545ad61e8f55c7f546f7f11c0938fc 179 SUPERFAMILY SSF52540 1 175 6.23E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_1363 0f545ad61e8f55c7f546f7f11c0938fc 179 Pfam PF13207 AAA domain 7 130 1.5E-11 T 23-10-2018 Mlab_1363 0f545ad61e8f55c7f546f7f11c0938fc 179 Gene3D G3DSA:3.40.50.300 1 178 8.4E-37 T 23-10-2018 Mlab_1555 8e00f8a8f4b9f5b7b80a906bacc42c09 62 TIGRFAM TIGR02507 MtrF: tetrahydromethanopterin S-methyltransferase, F subunit 8 60 3.8E-14 T 23-10-2018 IPR013347 Tetrahydromethanopterin S-methyltransferase, F subunit GO:0015948|GO:0016020|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1555 8e00f8a8f4b9f5b7b80a906bacc42c09 62 Pfam PF09472 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) 6 60 9.0E-23 T 23-10-2018 IPR013347 Tetrahydromethanopterin S-methyltransferase, F subunit GO:0015948|GO:0016020|GO:0030269 KEGG: 00680+2.1.1.86 Mlab_1337 1ec69e9448498a6e808ffb4f8eb34a46 76 Gene3D G3DSA:3.30.310.50 3 76 3.3E-18 T 23-10-2018 Mlab_1337 1ec69e9448498a6e808ffb4f8eb34a46 76 Pfam PF09341 Transcription factor Pcc1 9 75 9.9E-9 T 23-10-2018 IPR015419 CTAG/Pcc1 family Mlab_1716 a6b231f7025dbecd658d3c6ecaa9c98c 498 Gene3D G3DSA:1.20.1730.10 25 494 1.7E-93 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily Mlab_1716 a6b231f7025dbecd658d3c6ecaa9c98c 498 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 37 437 9.9E-86 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Mlab_1716 a6b231f7025dbecd658d3c6ecaa9c98c 498 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 9 489 2.0E-173 T 23-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 Mlab_1716 a6b231f7025dbecd658d3c6ecaa9c98c 498 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 419 439 - T 23-10-2018 IPR018212 Sodium/solute symporter, conserved site Mlab_1716 a6b231f7025dbecd658d3c6ecaa9c98c 498 Pfam PF00474 Sodium:solute symporter family 37 437 1.4E-95 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Mlab_1512 7310ad1f0b8d4d1b8ed0b459669b1563 101 Gene3D G3DSA:2.40.10.230 1 76 3.9E-13 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain Mlab_1512 7310ad1f0b8d4d1b8ed0b459669b1563 101 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 8 74 7.0E-6 T 23-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 Mlab_1512 7310ad1f0b8d4d1b8ed0b459669b1563 101 Pfam PF04410 Gar1/Naf1 RNA binding region 5 78 5.3E-7 T 23-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 Mlab_1512 7310ad1f0b8d4d1b8ed0b459669b1563 101 SUPERFAMILY SSF50447 1 75 1.59E-10 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Mlab_0840 4f10cf0f37486fba2094356842ac4f77 238 SUPERFAMILY SSF54862 152 230 1.83E-5 T 23-10-2018 Mlab_1634 656b9105d1f97c17f91ec476a92dc2ed 220 Hamap MF_00763 UPF0305 protein . 47 219 23.748 T 23-10-2018 IPR019215 Protein of unknown function DUF2115 Mlab_1634 656b9105d1f97c17f91ec476a92dc2ed 220 Pfam PF09888 Uncharacterized protein conserved in archaea (DUF2115) 53 217 4.3E-45 T 23-10-2018 IPR019215 Protein of unknown function DUF2115 Mlab_0959 8f991c4a4c8d182a931bdf071566b649 406 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 121 376 1.5E-68 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0959 8f991c4a4c8d182a931bdf071566b649 406 SUPERFAMILY SSF56762 16 376 5.36E-109 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0959 8f991c4a4c8d182a931bdf071566b649 406 Pfam PF00374 Nickel-dependent hydrogenase 45 113 5.0E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 Mlab_0959 8f991c4a4c8d182a931bdf071566b649 406 Gene3D G3DSA:1.10.645.20 7 376 1.6E-124 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0677 89c8945bcc54269a94f3d7e8e4abcc16 158 Gene3D G3DSA:3.40.1280.10 1 158 7.2E-55 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Mlab_0677 89c8945bcc54269a94f3d7e8e4abcc16 158 PIRSF PIRSF004505 1 158 1.9E-49 T 23-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Mlab_0677 89c8945bcc54269a94f3d7e8e4abcc16 158 Pfam PF02590 Predicted SPOUT methyltransferase 1 157 6.6E-50 T 23-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Mlab_0677 89c8945bcc54269a94f3d7e8e4abcc16 158 SUPERFAMILY SSF75217 1 156 1.67E-46 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases Mlab_0677 89c8945bcc54269a94f3d7e8e4abcc16 158 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 158 28.056 T 23-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Mlab_0424 4ee2bb4fad80955e7da6c5770c7a6360 239 Gene3D G3DSA:2.40.128.270 30 137 5.5E-18 T 23-10-2018 IPR038670 HslJ-like superfamily Mlab_0424 4ee2bb4fad80955e7da6c5770c7a6360 239 Gene3D G3DSA:2.40.128.270 142 239 2.3E-14 T 23-10-2018 IPR038670 HslJ-like superfamily Mlab_0424 4ee2bb4fad80955e7da6c5770c7a6360 239 Pfam PF03724 META domain 149 236 2.3E-16 T 23-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ Mlab_0424 4ee2bb4fad80955e7da6c5770c7a6360 239 Pfam PF03724 META domain 32 135 2.2E-20 T 23-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ Mlab_1633 fd3213507eba43e3c61befe6ab2db2ea 423 Pfam PF00999 Sodium/hydrogen exchanger family 15 399 1.5E-63 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Mlab_1633 fd3213507eba43e3c61befe6ab2db2ea 423 Gene3D G3DSA:1.20.1530.20 8 409 9.4E-82 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily Mlab_0891 5e22a5764c19e70de68ad248b727c24e 359 PIRSF PIRSF015268 8 351 2.0E-134 T 23-10-2018 IPR011204 Virulence protein RhuM-like Mlab_0891 5e22a5764c19e70de68ad248b727c24e 359 Pfam PF13310 Virulence protein RhuM family 72 322 1.5E-106 T 23-10-2018 IPR011204 Virulence protein RhuM-like Mlab_1533 451143ea86381949682feedc1d1c8de8 225 Pfam PF07790 Archaeal Type IV pilin, N-terminal 8 93 1.2E-15 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_1051 7e2c805262394f82a365f11836356cb2 636 SUPERFAMILY SSF53383 31 624 5.73E-83 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Mlab_1051 7e2c805262394f82a365f11836356cb2 636 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 396 417 - T 23-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 Mlab_1051 7e2c805262394f82a365f11836356cb2 636 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 249 344 3.3E-14 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 Mlab_1051 7e2c805262394f82a365f11836356cb2 636 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 382 496 4.5E-7 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 Mlab_1539 c625256ae481bd218c308f859d22ad5b 141 Pfam PF07790 Archaeal Type IV pilin, N-terminal 8 79 1.3E-14 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_1252 dbc9451cbc10dce5eb6f26322b22b0b3 354 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 131 326 4.5E-21 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 Mlab_1252 dbc9451cbc10dce5eb6f26322b22b0b3 354 SUPERFAMILY SSF140914 9 230 1.23E-43 T 23-10-2018 Mlab_1252 dbc9451cbc10dce5eb6f26322b22b0b3 354 Hamap MF_00701 DNA primase large subunit PriL [priL]. 11 327 34.632 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 Mlab_1653 9b7ab134f678809cd68690478c283ccb 345 ProDom PD017907 3-DEHYDROQUINATE UPF0245 SYNTHASE LYASE PREDICTED SYNTHASE-LIKE ALTERNATIVE T19N8 MM1272 MK1408 94 344 2.0E-66 T 23-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 Mlab_1653 9b7ab134f678809cd68690478c283ccb 345 Hamap MF_01244 3-dehydroquinate synthase [aroB']. 5 345 36.44 T 23-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 Mlab_1653 9b7ab134f678809cd68690478c283ccb 345 Pfam PF01959 3-dehydroquinate synthase (EC 4.6.1.3) 16 345 8.2E-117 T 23-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 Mlab_1111 95aff962bdd5495b79c347d05df2c7d1 284 SUPERFAMILY SSF63380 4 90 4.73E-17 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Mlab_1111 95aff962bdd5495b79c347d05df2c7d1 284 Gene3D G3DSA:2.40.30.10 2 90 1.1E-17 T 23-10-2018 Mlab_1111 95aff962bdd5495b79c347d05df2c7d1 284 Gene3D G3DSA:3.40.50.80 100 204 2.7E-33 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Mlab_1111 95aff962bdd5495b79c347d05df2c7d1 284 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 214 250 5.1E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain Mlab_1111 95aff962bdd5495b79c347d05df2c7d1 284 PIRSF PIRSF006816 1 256 3.9E-63 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 Mlab_1111 95aff962bdd5495b79c347d05df2c7d1 284 SUPERFAMILY SSF52343 93 249 6.48E-27 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Mlab_1745 395403df12f9db53a40b580962234fc6 506 Pfam PF10113 Fibrillarin-like archaeal protein 1 503 3.4E-262 T 23-10-2018 IPR016760 Methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC Mlab_1745 395403df12f9db53a40b580962234fc6 506 TIGRFAM TIGR03958 monoFe_hyd_HmdC: 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC 1 506 2.9E-263 T 23-10-2018 IPR016760 Methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC Mlab_1026 9a6f0ccc6e3d4cdeead809f350201c3c 182 Pfam PF00174 Oxidoreductase molybdopterin binding domain 72 181 1.6E-8 T 23-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 Mlab_1026 9a6f0ccc6e3d4cdeead809f350201c3c 182 Gene3D G3DSA:3.90.420.10 20 182 8.2E-9 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Mlab_1026 9a6f0ccc6e3d4cdeead809f350201c3c 182 SUPERFAMILY SSF56524 25 180 4.58E-15 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Mlab_1031 17e8d01e94240c2f06018694777d868e 90 Gene3D G3DSA:3.30.70.260 1 90 2.5E-26 T 23-10-2018 Mlab_1031 17e8d01e94240c2f06018694777d868e 90 Pfam PF13740 ACT domain 5 79 1.4E-11 T 23-10-2018 Mlab_1031 17e8d01e94240c2f06018694777d868e 90 SUPERFAMILY SSF55021 3 84 9.17E-19 T 23-10-2018 Mlab_1031 17e8d01e94240c2f06018694777d868e 90 Hamap MF_01054 UPF0237 protein . 2 90 24.546 T 23-10-2018 IPR022986 Uncharacterised protein family UPF0237, ACT-type Mlab_1055 a6b036af91a63c08c16db4952f58e699 200 SUPERFAMILY SSF54001 17 133 6.31E-20 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Mlab_1055 a6b036af91a63c08c16db4952f58e699 200 Pfam PF01841 Transglutaminase-like superfamily 28 129 2.4E-12 T 23-10-2018 IPR002931 Transglutaminase-like Mlab_1055 a6b036af91a63c08c16db4952f58e699 200 Gene3D G3DSA:3.10.620.30 1 144 2.4E-16 T 23-10-2018 Mlab_1055 a6b036af91a63c08c16db4952f58e699 200 SMART SM00460 67 131 0.0014 T 23-10-2018 IPR002931 Transglutaminase-like Mlab_0899 656c38c8a3f534ccdfbb61d3362af0bc 312 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 27 285 4.2E-105 T 23-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 Mlab_0899 656c38c8a3f534ccdfbb61d3362af0bc 312 Pfam PF00483 Nucleotidyl transferase 29 281 1.8E-28 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Mlab_0899 656c38c8a3f534ccdfbb61d3362af0bc 312 SUPERFAMILY SSF53448 22 292 9.24E-60 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0899 656c38c8a3f534ccdfbb61d3362af0bc 312 Gene3D G3DSA:3.90.550.10 18 312 1.4E-78 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_0723 5a3f584bc81596875a4d9c7625aca1af 527 Gene3D G3DSA:3.40.190.10 71 269 6.5E-127 T 23-10-2018 Mlab_0723 5a3f584bc81596875a4d9c7625aca1af 527 Gene3D G3DSA:3.10.105.10 270 483 6.5E-127 T 23-10-2018 Mlab_0723 5a3f584bc81596875a4d9c7625aca1af 527 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 444 1.2E-88 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain Mlab_0723 5a3f584bc81596875a4d9c7625aca1af 527 PIRSF PIRSF002741 35 527 2.3E-98 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Mlab_0723 5a3f584bc81596875a4d9c7625aca1af 527 SUPERFAMILY SSF53850 38 519 1.13E-128 T 23-10-2018 Mlab_0166 249e1f5ca66200ed4f2a4ff100e6ab60 257 Gene3D G3DSA:3.40.50.150 19 227 3.5E-40 T 23-10-2018 Mlab_0166 249e1f5ca66200ed4f2a4ff100e6ab60 257 Pfam PF08241 Methyltransferase domain 55 150 1.7E-22 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Mlab_0166 249e1f5ca66200ed4f2a4ff100e6ab60 257 SUPERFAMILY SSF53335 3 254 1.43E-44 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Mlab_0772 c288e19946c4443f844da0ec1a4f83d9 198 Gene3D G3DSA:3.40.50.2020 29 198 6.0E-29 T 23-10-2018 Mlab_0772 c288e19946c4443f844da0ec1a4f83d9 198 Pfam PF00156 Phosphoribosyl transferase domain 78 197 1.0E-20 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Mlab_0772 c288e19946c4443f844da0ec1a4f83d9 198 Hamap MF_01214 PyrE-like protein. 1 198 38.138 T 23-10-2018 IPR022854 PyrE-like Mlab_0772 c288e19946c4443f844da0ec1a4f83d9 198 SUPERFAMILY SSF53271 54 195 5.64E-25 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like Mlab_0751 c696ac4fe61ed941d897e5cf0b1d6fe5 208 Gene3D G3DSA:3.40.50.300 12 207 7.0E-30 T 23-10-2018 Mlab_0751 c696ac4fe61ed941d897e5cf0b1d6fe5 208 PRINTS PR00449 Transforming protein P21 ras signature 155 168 7.1E-6 T 23-10-2018 Mlab_0751 c696ac4fe61ed941d897e5cf0b1d6fe5 208 PRINTS PR00449 Transforming protein P21 ras signature 185 207 7.1E-6 T 23-10-2018 Mlab_0751 c696ac4fe61ed941d897e5cf0b1d6fe5 208 PRINTS PR00449 Transforming protein P21 ras signature 20 41 7.1E-6 T 23-10-2018 Mlab_0751 c696ac4fe61ed941d897e5cf0b1d6fe5 208 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 18 203 3.7E-12 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Mlab_0751 c696ac4fe61ed941d897e5cf0b1d6fe5 208 SUPERFAMILY SSF52540 18 202 4.04E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0751 c696ac4fe61ed941d897e5cf0b1d6fe5 208 Pfam PF01926 50S ribosome-binding GTPase 21 165 1.9E-15 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 Mlab_0359 12cf869b938b38b5142b99f2f9eaab92 250 Gene3D G3DSA:3.40.50.10090 20 134 4.8E-10 T 23-10-2018 Mlab_0359 12cf869b938b38b5142b99f2f9eaab92 250 SUPERFAMILY SSF69618 21 248 1.29E-34 T 23-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0359 12cf869b938b38b5142b99f2f9eaab92 250 Pfam PF02602 Uroporphyrinogen-III synthase HemD 37 231 1.1E-20 T 23-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0359 12cf869b938b38b5142b99f2f9eaab92 250 Gene3D G3DSA:3.40.50.10090 137 244 3.5E-8 T 23-10-2018 Mlab_1677 8d537ce5f54f14a370a9e6ac85a3a097 195 SUPERFAMILY SSF52218 4 190 6.71E-31 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1677 8d537ce5f54f14a370a9e6ac85a3a097 195 Gene3D G3DSA:3.40.50.360 3 190 1.9E-40 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1677 8d537ce5f54f14a370a9e6ac85a3a097 195 Pfam PF03358 NADPH-dependent FMN reductase 4 134 1.3E-20 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Mlab_0951 a640aef31165f2868335c5c8183942d0 90 Pfam PF13244 Domain of unknown function (DUF4040) 19 84 3.5E-18 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 Mlab_0106 ac3479caabfdf18f53f34aba82942b47 211 Pfam PF01956 Integral membrane protein DUF106 40 209 2.9E-45 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 Mlab_0106 ac3479caabfdf18f53f34aba82942b47 211 SMART SM01415 40 210 2.4E-51 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 Mlab_1315 2f17a9810ef3147578e1d9828d8084d0 145 SMART SM00535 18 145 3.3E-10 T 23-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 Mlab_1315 2f17a9810ef3147578e1d9828d8084d0 145 Pfam PF14622 Ribonuclease-III-like 18 141 1.3E-23 T 23-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 Mlab_1315 2f17a9810ef3147578e1d9828d8084d0 145 Gene3D G3DSA:1.10.1520.10 4 144 4.8E-31 T 23-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 Mlab_1315 2f17a9810ef3147578e1d9828d8084d0 145 SUPERFAMILY SSF69065 3 145 8.55E-31 T 23-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 Mlab_0918 bbc60d4aadea63f16c020692cc636dfb 183 Pfam PF01965 DJ-1/PfpI family 14 179 2.4E-35 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 Mlab_0918 bbc60d4aadea63f16c020692cc636dfb 183 Gene3D G3DSA:3.40.50.880 9 183 5.8E-41 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_0918 bbc60d4aadea63f16c020692cc636dfb 183 SUPERFAMILY SSF52317 14 182 1.27E-34 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_1048 7c134625cb172f1a4e602c63c9b71061 215 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 171 9.3E-6 T 23-10-2018 IPR003740 Uncharacterised membrane protein YitT Mlab_0957 a633a98c58d96cb49365e9e82c9efbc6 143 Gene3D G3DSA:3.40.50.12280 4 142 7.2E-56 T 23-10-2018 Mlab_0957 a633a98c58d96cb49365e9e82c9efbc6 143 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 8 136 5.5E-43 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0957 a633a98c58d96cb49365e9e82c9efbc6 143 SUPERFAMILY SSF56770 9 138 1.2E-54 T 23-10-2018 Mlab_0957 a633a98c58d96cb49365e9e82c9efbc6 143 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 21 130 1.1E-26 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_1622 5af18b9c1a17332e07afab0fee08fac1 144 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 18 128 1.9E-25 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_1622 5af18b9c1a17332e07afab0fee08fac1 144 Gene3D G3DSA:3.40.50.12280 2 144 1.4E-48 T 23-10-2018 Mlab_1622 5af18b9c1a17332e07afab0fee08fac1 144 SUPERFAMILY SSF56770 6 137 5.36E-51 T 23-10-2018 Mlab_0888 fb31f2e5827f4c66ea10c3e0ccd770ee 276 Gene3D G3DSA:1.10.10.10 207 262 1.0E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0888 fb31f2e5827f4c66ea10c3e0ccd770ee 276 Gene3D G3DSA:3.30.565.60 21 184 8.3E-37 T 23-10-2018 IPR038475 RecG, C-terminal domain superfamily Mlab_0888 fb31f2e5827f4c66ea10c3e0ccd770ee 276 Pfam PF08279 HTH domain 208 248 1.1E-4 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 Mlab_0888 fb31f2e5827f4c66ea10c3e0ccd770ee 276 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 94 181 9.0E-24 T 23-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain Mlab_0888 fb31f2e5827f4c66ea10c3e0ccd770ee 276 SUPERFAMILY SSF46785 203 259 1.5E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1421 526e04150f75eee30453860398b0a4e1 256 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 216 2.8E-23 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase Mlab_0774 7f5c4a67059e0606e06702ddc189c9e9 158 Pfam PF17146 PIN domain of ribonuclease 16 87 1.7E-16 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 Mlab_0774 7f5c4a67059e0606e06702ddc189c9e9 158 Gene3D G3DSA:3.40.50.1010 1 119 2.7E-30 T 23-10-2018 Mlab_0566 4067a2b18ac5949f798c08c8f89cb488 206 Pfam PF09878 Predicted membrane protein (DUF2105) 9 201 4.6E-70 T 23-10-2018 IPR019212 Protein of unknown function DUF2105, membrane Mlab_1705 77f5d6ffaef03622847c79399c942eb1 303 SUPERFAMILY SSF53474 96 284 9.51E-7 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold Mlab_1705 77f5d6ffaef03622847c79399c942eb1 303 Pfam PF11288 Protein of unknown function (DUF3089) 25 214 2.7E-58 T 23-10-2018 IPR021440 Protein of unknown function DUF3089 Mlab_0499 9e57740b15c866bbb802b518f402216d 263 Pfam PF00005 ABC transporter 31 173 1.7E-12 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Mlab_0499 9e57740b15c866bbb802b518f402216d 263 Gene3D G3DSA:3.40.50.300 28 253 2.5E-26 T 23-10-2018 Mlab_0499 9e57740b15c866bbb802b518f402216d 263 SUPERFAMILY SSF52540 30 224 1.36E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0499 9e57740b15c866bbb802b518f402216d 263 SMART SM00382 33 217 1.9E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain Mlab_0791 5011bcc81593accf72ba72b2aede9bfb 206 PRINTS PR01217 Proline rich extensin signature 19 40 6.8E-10 T 23-10-2018 Mlab_0791 5011bcc81593accf72ba72b2aede9bfb 206 PRINTS PR01217 Proline rich extensin signature 40 56 6.8E-10 T 23-10-2018 Mlab_0791 5011bcc81593accf72ba72b2aede9bfb 206 PRINTS PR01217 Proline rich extensin signature 73 98 6.8E-10 T 23-10-2018 Mlab_1052 54ba9e6520e7298e72cde73050ee8ce1 222 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 13 217 3.7E-15 T 23-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 Mlab_0457 d4a98951b30f4b550ff6fb53ed47d5eb 357 SUPERFAMILY SSF56059 80 279 7.6E-31 T 23-10-2018 Mlab_0457 d4a98951b30f4b550ff6fb53ed47d5eb 357 Gene3D G3DSA:3.30.470.20 139 272 1.8E-21 T 23-10-2018 Mlab_0457 d4a98951b30f4b550ff6fb53ed47d5eb 357 Pfam PF02655 ATP-grasp domain 95 252 2.2E-31 T 23-10-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 Mlab_0320 c5636e844bfce012ff3f8f3ffbeeb93f 214 Pfam PF09888 Uncharacterized protein conserved in archaea (DUF2115) 27 183 2.2E-44 T 23-10-2018 IPR019215 Protein of unknown function DUF2115 Mlab_0320 c5636e844bfce012ff3f8f3ffbeeb93f 214 Hamap MF_00763 UPF0305 protein . 25 186 23.826 T 23-10-2018 IPR019215 Protein of unknown function DUF2115 Mlab_0627 764bc525f5eae5181dd19ac37f5be8b9 53 Pfam PF07754 Domain of unknown function (DUF1610) 6 28 7.3E-11 T 23-10-2018 IPR011668 Domain of unknown function DUF1610 Mlab_1137 06f1874258f89d716b861cba6f216355 248 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 3 228 1.9E-58 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 Mlab_1137 06f1874258f89d716b861cba6f216355 248 Gene3D G3DSA:1.10.8.590 160 239 3.2E-6 T 23-10-2018 Mlab_1137 06f1874258f89d716b861cba6f216355 248 PIRSF PIRSF004808 1 233 3.5E-64 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 Mlab_1137 06f1874258f89d716b861cba6f216355 248 Pfam PF00588 SpoU rRNA Methylase family 5 154 6.7E-27 T 23-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Mlab_1137 06f1874258f89d716b861cba6f216355 248 Gene3D G3DSA:3.40.1280.10 1 159 3.9E-47 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Mlab_1137 06f1874258f89d716b861cba6f216355 248 SUPERFAMILY SSF75217 3 158 4.19E-27 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 402 9.1E-39 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 Gene3D G3DSA:1.10.287.40 1 107 6.3E-25 T 23-10-2018 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 419 3.0E-152 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 Gene3D G3DSA:3.30.930.10 108 425 3.9E-131 T 23-10-2018 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 5.1E-21 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 424 37.938 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 PRINTS PR00981 Seryl-tRNA synthetase signature 352 368 1.5E-29 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 PRINTS PR00981 Seryl-tRNA synthetase signature 265 277 1.5E-29 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 PRINTS PR00981 Seryl-tRNA synthetase signature 277 290 1.5E-29 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 PRINTS PR00981 Seryl-tRNA synthetase signature 317 330 1.5E-29 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 PRINTS PR00981 Seryl-tRNA synthetase signature 334 350 1.5E-29 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 SUPERFAMILY SSF46589 1 115 5.75E-22 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 PIRSF PIRSF001529 1 425 1.4E-152 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Mlab_0710 82f5ca6bf324ffb42666dc19baef6e1e 425 SUPERFAMILY SSF55681 117 420 6.36E-93 T 23-10-2018 Mlab_0779 464dfa4968f9bdddc9f8e0fe587a9d70 430 SUPERFAMILY SSF111283 7 430 2.62E-79 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 Mlab_0779 464dfa4968f9bdddc9f8e0fe587a9d70 430 Pfam PF01523 Putative modulator of DNA gyrase 19 302 1.8E-42 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 Mlab_0779 464dfa4968f9bdddc9f8e0fe587a9d70 430 Gene3D G3DSA:3.30.2290.10 2 208 5.2E-20 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal Mlab_1449 4a0f6485abdd7bc14d6159e1c079dc25 315 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 118 9.4E-19 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase Mlab_0396 376c4032737f1635c84876c4e9642d7e 219 SUPERFAMILY SSF55821 3 202 1.63E-81 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Mlab_0396 376c4032737f1635c84876c4e9642d7e 219 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 4 199 1.9E-74 T 23-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0396 376c4032737f1635c84876c4e9642d7e 219 Gene3D G3DSA:3.90.870.10 1 206 2.9E-85 T 23-10-2018 Mlab_0396 376c4032737f1635c84876c4e9642d7e 219 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 2 203 37.376 T 23-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0396 376c4032737f1635c84876c4e9642d7e 219 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 198 2.8E-83 T 23-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Mlab_0925 fadce7dc6d48c8175bf7fd447f784774 97 Pfam PF04242 Protein of unknown function (DUF424) 6 95 7.7E-26 T 23-10-2018 IPR007355 Protein of unknown function DUF424 Mlab_0925 fadce7dc6d48c8175bf7fd447f784774 97 Gene3D G3DSA:3.30.1860.10 1 97 2.6E-21 T 23-10-2018 Mlab_1270 dcdf42f0d90eff5f9bb10d5e52bb502e 95 Gene3D G3DSA:1.10.10.10 1 94 2.0E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1270 dcdf42f0d90eff5f9bb10d5e52bb502e 95 SUPERFAMILY SSF46785 11 76 5.46E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_1336 80606c7d75bdfa85f9bd274a32ea5674 125 Pfam PF01920 Prefoldin subunit 15 117 1.4E-22 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 Mlab_1336 80606c7d75bdfa85f9bd274a32ea5674 125 Gene3D G3DSA:1.10.287.370 8 121 2.4E-35 T 23-10-2018 IPR009053 Prefoldin Mlab_1336 80606c7d75bdfa85f9bd274a32ea5674 125 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 10 118 6.9E-34 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 Mlab_1336 80606c7d75bdfa85f9bd274a32ea5674 125 SUPERFAMILY SSF46579 12 117 6.15E-23 T 23-10-2018 Mlab_1336 80606c7d75bdfa85f9bd274a32ea5674 125 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 125 44.704 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 Mlab_1429 2c88c3077947798fde438bb83d197f20 379 Pfam PF01757 Acyltransferase family 10 365 9.6E-34 T 23-10-2018 IPR002656 Acyltransferase 3 GO:0016747 Mlab_0934 b0ff2b321b3ba773cdb29c59cc856e2f 576 Pfam PF09843 Predicted membrane protein (DUF2070) 8 567 2.7E-175 T 23-10-2018 IPR019204 Domain of unknown function DUF2070, membrane Mlab_1644 50f4eef2b816ad68f2365f5d777a78cb 193 Gene3D G3DSA:3.40.920.10 1 193 2.6E-50 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Mlab_1644 50f4eef2b816ad68f2365f5d777a78cb 193 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 190 2.5E-39 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Mlab_1644 50f4eef2b816ad68f2365f5d777a78cb 193 SUPERFAMILY SSF53323 5 193 3.79E-41 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Mlab_1596 643118712f6ac2131896b232fb2e262b 225 Pfam PF16316 Domain of unknown function (DUF4956) 31 143 6.8E-10 T 23-10-2018 IPR032531 Protein of unknown function DUF4956 Mlab_0333 09dae0684d1b0e8d398dca280e18fdec 237 Pfam PF00881 Nitroreductase family 9 209 4.7E-35 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Mlab_0333 09dae0684d1b0e8d398dca280e18fdec 237 SUPERFAMILY SSF55469 2 234 1.81E-34 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Mlab_0073 5e1e04ccf03e25263ef9fdc6609eaa6f 231 Pfam PF02602 Uroporphyrinogen-III synthase HemD 16 200 4.3E-13 T 23-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0073 5e1e04ccf03e25263ef9fdc6609eaa6f 231 SUPERFAMILY SSF69618 3 224 7.98E-23 T 23-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Mlab_0073 5e1e04ccf03e25263ef9fdc6609eaa6f 231 Gene3D G3DSA:3.40.50.10090 60 148 1.4E-7 T 23-10-2018 Mlab_0596 44c8c0249385b9ff76e41ca2c66135f6 222 Pfam PF14353 CpXC protein 8 130 7.0E-33 T 23-10-2018 IPR025682 CpXC domain Mlab_1666 1355a7a55fcb4bef7a4ff918f2eab060 67 Gene3D G3DSA:1.10.260.40 3 67 2.1E-12 T 23-10-2018 Mlab_1666 1355a7a55fcb4bef7a4ff918f2eab060 67 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 66 2.4E-23 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_1666 1355a7a55fcb4bef7a4ff918f2eab060 67 SUPERFAMILY SSF47413 1 65 5.35E-18 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Mlab_1666 1355a7a55fcb4bef7a4ff918f2eab060 67 SMART SM00530 6 62 3.9E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Mlab_1518 d863ac22c6948be5deb316e6e43abe0c 158 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 3 151 7.4E-50 T 23-10-2018 IPR018716 Protein of unknown function DUF2240 Mlab_1589 c01bf21eab2834ea215e7acf34851e8d 264 Pfam PF07786 Protein of unknown function (DUF1624) 14 241 6.0E-56 T 23-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 Mlab_1362 6e6b30499960ac5acaad7187e8aec09f 116 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 1 35 5.6E-12 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 Mlab_1294 252b76f1e64df151de74d52227a55bb8 159 Pfam PF00011 Hsp20/alpha crystallin family 58 158 2.6E-10 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Mlab_1294 252b76f1e64df151de74d52227a55bb8 159 Gene3D G3DSA:2.60.40.790 12 159 7.7E-26 T 23-10-2018 IPR008978 HSP20-like chaperone Mlab_1294 252b76f1e64df151de74d52227a55bb8 159 SUPERFAMILY SSF49764 51 158 1.53E-23 T 23-10-2018 IPR008978 HSP20-like chaperone Mlab_1033 858f19649d62e1ced9c8215b6ec8c4f9 149 Pfam PF13366 PD-(D/E)XK nuclease superfamily 19 132 2.5E-37 T 23-10-2018 IPR026350 GxxExxY protein Mlab_1033 858f19649d62e1ced9c8215b6ec8c4f9 149 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 19 133 6.0E-40 T 23-10-2018 IPR026350 GxxExxY protein Mlab_0859 414a7941734400db80c43605ad8c4582 593 Pfam PF13271 Domain of unknown function (DUF4062) 38 127 3.3E-21 T 23-10-2018 IPR025139 Domain of unknown function DUF4062 Mlab_1377 2f917b3d24a8ad6a60294b7a29222475 315 Pfam PF01032 FecCD transport family 13 311 4.6E-93 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Mlab_1377 2f917b3d24a8ad6a60294b7a29222475 315 SUPERFAMILY SSF81345 3 312 5.49E-86 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_1377 2f917b3d24a8ad6a60294b7a29222475 315 Gene3D G3DSA:1.10.3470.10 3 315 1.6E-101 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_1536 05e777fe7ec113885c458c9105f22aec 578 Gene3D G3DSA:3.10.620.30 111 200 1.7E-6 T 23-10-2018 Mlab_1468 ee8bba7ff735fc941344c2089cb296dc 523 Pfam PF07790 Archaeal Type IV pilin, N-terminal 6 75 1.6E-8 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_1468 ee8bba7ff735fc941344c2089cb296dc 523 SUPERFAMILY SSF51126 262 496 1.96E-9 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor Mlab_1673 a40a1b0128a41cfdb15dc22e577819c3 475 SUPERFAMILY SSF51717 132 353 2.62E-24 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Mlab_0519 39255567589df8227a093e87df617017 381 SUPERFAMILY SSF53623 82 280 1.7E-8 T 23-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Mlab_0519 39255567589df8227a093e87df617017 381 Gene3D G3DSA:3.40.1190.10 72 180 1.8E-7 T 23-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Mlab_1446 e2914cdeffbcb7f671442d1d6d86d43c 423 TIGRFAM TIGR00261 traB: TraB family protein 3 393 9.4E-98 T 23-10-2018 IPR005230 Pheromone shutdown, TraB, bacterial/archaeal Mlab_1446 e2914cdeffbcb7f671442d1d6d86d43c 423 Pfam PF01963 TraB family 2 236 8.1E-28 T 23-10-2018 IPR002816 Pheromone shutdown, TraB Mlab_1338 bc4e7631df2ae69661c9e5f4f9d30954 133 Gene3D G3DSA:3.40.50.10480 1 132 7.9E-8 T 23-10-2018 Mlab_1338 bc4e7631df2ae69661c9e5f4f9d30954 133 SUPERFAMILY SSF52954 3 129 1.28E-16 T 23-10-2018 Mlab_1708 286ec6d74ded7f358c8822f7bc83a65e 504 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 400 425 9.5E-5 T 23-10-2018 IPR023908 xxxLxxG heptad repeat Mlab_0302 a1e6e11f88309b8361b45159303338a9 84 Pfam PF04994 TfoX C-terminal domain 3 79 3.0E-24 T 23-10-2018 IPR007077 TfoX, C-terminal Mlab_0302 a1e6e11f88309b8361b45159303338a9 84 Gene3D G3DSA:1.10.150.20 1 84 1.4E-32 T 23-10-2018 Mlab_0302 a1e6e11f88309b8361b45159303338a9 84 SUPERFAMILY SSF56672 4 56 6.0E-5 T 23-10-2018 Mlab_1180 f49ac444a212067302acb9cafe71f53d 151 Gene3D G3DSA:3.40.960.10 20 144 9.2E-43 T 23-10-2018 Mlab_1180 f49ac444a212067302acb9cafe71f53d 151 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 1 118 1.0E-39 T 23-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 Mlab_1180 f49ac444a212067302acb9cafe71f53d 151 Pfam PF03852 DNA mismatch endonuclease Vsr 1 71 1.6E-26 T 23-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 Mlab_1180 f49ac444a212067302acb9cafe71f53d 151 SUPERFAMILY SSF52980 1 135 1.77E-48 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Mlab_1180 f49ac444a212067302acb9cafe71f53d 151 PIRSF PIRSF018267 1 143 1.8E-52 T 23-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 Mlab_1702 627d3dab5b30830b48e71988fc8b9ebb 275 Pfam PF04254 Protein of unknown function (DUF432) 87 209 9.9E-34 T 23-10-2018 IPR007366 Protein of unknown function DUF432 Mlab_1702 627d3dab5b30830b48e71988fc8b9ebb 275 PIRSF PIRSF019202 32 272 5.6E-39 T 23-10-2018 IPR007366 Protein of unknown function DUF432 Mlab_1428 f9a4f6484151da075566443281dd239f 346 Gene3D G3DSA:3.90.550.10 3 210 2.6E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1428 f9a4f6484151da075566443281dd239f 346 Pfam PF00535 Glycosyl transferase family 2 9 128 2.3E-30 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Mlab_1428 f9a4f6484151da075566443281dd239f 346 SUPERFAMILY SSF53448 6 234 1.97E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Mlab_1542 ac39d0137e82de56b5e5f8210ef41098 153 Pfam PF07790 Archaeal Type IV pilin, N-terminal 7 78 3.8E-11 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_0997 a1516fd89b90a7355fc4586189bce5de 209 Gene3D G3DSA:1.20.58.220 14 209 2.3E-62 T 23-10-2018 IPR038078 PhoU-like domain superfamily Mlab_0997 a1516fd89b90a7355fc4586189bce5de 209 Pfam PF01865 Protein of unknown function DUF47 12 206 7.7E-27 T 23-10-2018 IPR018445 Putative phosphate transport regulator Mlab_0358 89e8f57155df42bcd924c3b4faf60c05 306 SMART SM00730 44 298 5.7E-24 T 23-10-2018 IPR006639 Presenilin/signal peptide peptidase GO:0004190|GO:0016021 Mlab_0358 89e8f57155df42bcd924c3b4faf60c05 306 Pfam PF06550 Signal-peptide peptidase, presenilin aspartyl protease 18 299 3.3E-74 T 23-10-2018 IPR010545 Signal-peptide peptidase, presenilin aspartyl protease Mlab_0886 89fb0486b3b49684f4ced1f8dd4e43ae 129 SUPERFAMILY SSF81301 21 120 7.73E-22 T 23-10-2018 Mlab_0886 89fb0486b3b49684f4ced1f8dd4e43ae 129 Pfam PF01909 Nucleotidyltransferase domain 41 115 1.2E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Mlab_0886 89fb0486b3b49684f4ced1f8dd4e43ae 129 Gene3D G3DSA:3.30.460.10 25 121 6.6E-22 T 23-10-2018 Mlab_1202 8270be04fda427fc8ef4d1f4bec5f427 241 Pfam PF14335 Domain of unknown function (DUF4391) 5 237 4.7E-34 T 23-10-2018 IPR025503 Protein of unknown function DUF4391 Mlab_1531 5aa8b2b3178d0ca79e2c42bc511a6779 217 Pfam PF07790 Archaeal Type IV pilin, N-terminal 8 102 5.7E-23 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_1331 a9bd6bd311b6969596d806fe76347afc 91 Gene3D G3DSA:3.90.820.10 3 74 1.5E-6 T 23-10-2018 Mlab_0753 e7c7150d70b6eaad91c455ebc71722b3 130 Pfam PF09845 Zn-ribbon containing protein 2 122 3.1E-44 T 23-10-2018 IPR018645 Zn-ribbon containing protein Mlab_0294 e21e227afca838ce97e85b5a3164a7e3 654 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 85 402 5.6E-86 T 23-10-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 Mlab_0294 e21e227afca838ce97e85b5a3164a7e3 654 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 390 456 1.0E-12 T 23-10-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 Mlab_0497 62ef903b19efd7306c88f514119f1238 252 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 75 1.7E-17 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal Mlab_0497 62ef903b19efd7306c88f514119f1238 252 SUPERFAMILY SSF46785 4 77 8.17E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0497 62ef903b19efd7306c88f514119f1238 252 Gene3D G3DSA:1.10.10.10 2 100 3.7E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0597 5d3d2766e3be80c8549553cd9a86299c 123 Pfam PF12675 Protein of unknown function (DUF3795) 8 56 7.0E-7 T 23-10-2018 IPR024227 Protein of unknown function DUF3795 Mlab_0480 5a22354f4471f6e08b176bf46fcb93be 375 Gene3D G3DSA:3.30.70.2200 212 360 4.4E-18 T 23-10-2018 Mlab_1020 0c4081ab65b76ea283f026a80c093582 325 Pfam PF07760 Protein of unknown function (DUF1616) 26 322 2.0E-105 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 Mlab_1020 0c4081ab65b76ea283f026a80c093582 325 PIRSF PIRSF018671 10 325 1.5E-93 T 23-10-2018 IPR014495 Uncharacterised conserved protein UCP018671 Mlab_1451 44b96d08b2d44a01eff9ad5b7bcc92d2 98 Pfam PF01740 STAS domain 6 96 5.4E-13 T 23-10-2018 IPR002645 STAS domain Mlab_1451 44b96d08b2d44a01eff9ad5b7bcc92d2 98 Gene3D G3DSA:3.30.750.24 3 98 2.0E-18 T 23-10-2018 IPR036513 STAS domain superfamily Mlab_1451 44b96d08b2d44a01eff9ad5b7bcc92d2 98 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 95 8.9E-17 T 23-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Mlab_1451 44b96d08b2d44a01eff9ad5b7bcc92d2 98 SUPERFAMILY SSF52091 1 95 2.16E-17 T 23-10-2018 IPR036513 STAS domain superfamily Mlab_0826 1bf07c46cc742c051853717bf1d19e85 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 21 84 8.0E-17 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal Mlab_0826 1bf07c46cc742c051853717bf1d19e85 264 SUPERFAMILY SSF46785 21 108 2.81E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0826 1bf07c46cc742c051853717bf1d19e85 264 Gene3D G3DSA:1.10.10.10 12 111 4.0E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_1098 e4176bd76eaf234b2c5490627f3b3d18 282 Pfam PF00950 ABC 3 transport family 11 265 1.5E-41 T 23-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 Mlab_1098 e4176bd76eaf234b2c5490627f3b3d18 282 SUPERFAMILY SSF81345 9 261 1.7E-22 T 23-10-2018 IPR037294 ABC transporter, BtuC-like Mlab_0242 c56a1e8d48fb95a8734b42ad479f46b4 142 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 9 131 1.1E-48 T 23-10-2018 IPR003813 F420-non-reducing hydrogenase iron-sulfur subunit D GO:0055114 Mlab_1530 bab0236adcef24bbeeec5f220e18d1c8 235 Pfam PF07790 Archaeal Type IV pilin, N-terminal 9 79 2.1E-16 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_0246 b7d2710ed4f4af9986a406f62d48dace 266 Gene3D G3DSA:2.160.20.60 91 220 3.1E-6 T 23-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Mlab_0246 b7d2710ed4f4af9986a406f62d48dace 266 Pfam PF01493 GXGXG motif 77 213 2.2E-8 T 23-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 Mlab_0246 b7d2710ed4f4af9986a406f62d48dace 266 SUPERFAMILY SSF69336 16 262 3.27E-43 T 23-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Mlab_0246 b7d2710ed4f4af9986a406f62d48dace 266 TIGRFAM TIGR03122 one_C_dehyd_C: formylmethanofuran dehydrogenase subunit C 4 232 7.5E-67 T 23-10-2018 IPR017550 Formylmethanofuran dehydrogenase subunit C GO:0015948|GO:0018493|GO:0046914|GO:0055114 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 Mlab_0501 c64aab4caf0127603aadea39363a7410 208 Pfam PF04060 Putative Fe-S cluster 6 37 4.4E-6 T 23-10-2018 IPR007202 4Fe-4S domain GO:0051536 Mlab_0916 3d5110de959d17a98559f4db679cb16e 430 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 13 408 3.1E-123 T 23-10-2018 IPR021228 Protein of unknown function DUF2791 Mlab_1564 0f84404258719e53503bf2b29b087b4a 157 ProDom PD005228 M D REDUCTASE METHYL-COENZYME OPERON METHANOGENESIS MULTIGENE FAMILY METHYL COENZYME 10 131 2.0E-28 T 23-10-2018 IPR003901 Methyl-coenzyme M reductase, protein D GO:0015948 Mlab_1564 0f84404258719e53503bf2b29b087b4a 157 PIRSF PIRSF005636 4 156 1.2E-42 T 23-10-2018 IPR003901 Methyl-coenzyme M reductase, protein D GO:0015948 Mlab_1564 0f84404258719e53503bf2b29b087b4a 157 TIGRFAM TIGR03260 met_CoM_red_D: methyl-coenzyme M reductase operon protein D 8 152 1.2E-45 T 23-10-2018 IPR003901 Methyl-coenzyme M reductase, protein D GO:0015948 Mlab_1564 0f84404258719e53503bf2b29b087b4a 157 Pfam PF02505 Methyl-coenzyme M reductase operon protein D 8 148 7.5E-52 T 23-10-2018 IPR003901 Methyl-coenzyme M reductase, protein D GO:0015948 Mlab_1532 175b7086ee3a3d2941d43fd39754940c 229 Pfam PF07790 Archaeal Type IV pilin, N-terminal 14 95 1.8E-25 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_1193 814866d97ad151e80065833d4f5dfda1 161 Pfam PF03692 Putative zinc- or iron-chelating domain 6 96 3.9E-5 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein Mlab_1740 69303da54b25dc95a1f69bfdeead565a 260 Pfam PF06690 Protein of unknown function (DUF1188) 3 251 1.7E-96 T 23-10-2018 IPR009573 Protein of unknown function DUF1188 Mlab_1635 d6210168ad44ab95ef707195d2f364ef 323 Pfam PF04332 Protein of unknown function (DUF475) 22 311 1.7E-48 T 23-10-2018 IPR007427 Protein of unknown function DUF475 Mlab_0509 8accf9138e1ce6725ef5a9720d0ac8d6 644 Pfam PF04893 Yip1 domain 471 635 7.8E-12 T 23-10-2018 IPR006977 Yip1 domain GO:0016020 Mlab_1595 5dd6e8cda93ede75e0651907b8f24603 228 Gene3D G3DSA:2.40.320.20 4 225 1.9E-5 T 23-10-2018 Mlab_1595 5dd6e8cda93ede75e0651907b8f24603 228 Pfam PF09359 VTC domain 7 224 2.8E-25 T 23-10-2018 IPR018966 VTC domain Mlab_1587 691443d115572494c8da99f850a9ea76 277 Pfam PF07786 Protein of unknown function (DUF1624) 26 259 5.3E-48 T 23-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 Mlab_0945 71939b1c6e4f1296c33400ed942a7aab 227 Pfam PF13197 Protein of unknown function (DUF4013) 29 200 1.5E-23 T 23-10-2018 IPR025098 Protein of unknown function DUF4013 Mlab_0872 a4601398fc27cbc2d9c452e9df548aa5 240 Pfam PF06695 Putative small multi-drug export protein 88 188 3.5E-14 T 23-10-2018 IPR009577 Putative small multi-drug export Mlab_0565 721597f48fcdb3514a27bbcc29d27edc 170 PIRSF PIRSF019373 18 170 1.7E-52 T 23-10-2018 IPR011313 Predicted [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaF Mlab_0565 721597f48fcdb3514a27bbcc29d27edc 170 Pfam PF09879 Predicted membrane protein (DUF2106) 22 167 8.3E-66 T 23-10-2018 IPR011313 Predicted [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaF Mlab_0873 83fa0a4ffe3c8987c0cc8d84f75c2819 227 Pfam PF06695 Putative small multi-drug export protein 64 177 7.0E-8 T 23-10-2018 IPR009577 Putative small multi-drug export Mlab_0741 f19b8043b3aa3da03ef5c39c1f0a1243 393 Pfam PF04123 Domain of unknown function (DUF373) 4 347 6.7E-116 T 23-10-2018 IPR007254 Protein of unknown function DUF373 Mlab_1145 8d4556579a6ae99c44bad777fbc016b7 225 SUPERFAMILY SSF56300 2 209 1.7E-57 T 23-10-2018 Mlab_1145 8d4556579a6ae99c44bad777fbc016b7 225 Pfam PF00149 Calcineurin-like phosphoesterase 4 174 2.2E-18 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Mlab_1145 8d4556579a6ae99c44bad777fbc016b7 225 Gene3D G3DSA:3.60.21.10 1 211 6.8E-29 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like Mlab_1217 7096fc9a5a67fcf4ab7e7c8276e41f38 661 Pfam PF01496 V-type ATPase 116kDa subunit family 176 420 9.8E-18 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_1217 7096fc9a5a67fcf4ab7e7c8276e41f38 661 Pfam PF01496 V-type ATPase 116kDa subunit family 550 652 3.1E-11 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Mlab_0318 6b29caf69889335e07f1e935ec12ab5c 185 Hamap MF_01117 CDP-archaeol synthase [carS]. 10 185 28.952 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 Mlab_0318 6b29caf69889335e07f1e935ec12ab5c 185 Pfam PF01864 CDP-archaeol synthase 4 185 9.0E-44 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 Mlab_1383 a4d62218bc8b97f80b80736d32eeafc9 229 SUPERFAMILY SSF51569 18 116 3.85E-7 T 23-10-2018 Mlab_1383 a4d62218bc8b97f80b80736d32eeafc9 229 Hamap MF_00681 (5-formylfuran-3-yl)methyl phosphate synthase [mfnB]. 1 228 41.321 T 23-10-2018 IPR035081 (5-formylfuran-3-yl)methyl phosphate synthase, archaea GO:0016830|GO:2001120 KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 Mlab_1383 a4d62218bc8b97f80b80736d32eeafc9 229 PIRSF PIRSF015957 1 229 3.7E-83 T 23-10-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 Mlab_1383 a4d62218bc8b97f80b80736d32eeafc9 229 Pfam PF04476 4-HFC-P synthase 3 223 6.6E-80 T 23-10-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 Mlab_0482 00863c7f23a03627b87e97b0e93998e0 171 Pfam PF01842 ACT domain 7 73 1.4E-7 T 23-10-2018 IPR002912 ACT domain Mlab_0482 00863c7f23a03627b87e97b0e93998e0 171 SUPERFAMILY SSF55021 3 78 2.17E-5 T 23-10-2018 Mlab_1323 e29fd7a355883b407a65590694a1ea00 344 Gene3D G3DSA:3.60.60.10 83 335 4.6E-22 T 23-10-2018 Mlab_0661 e8fa6a116b579abda8b8013572b1cbd6 91 Pfam PF09871 Uncharacterized protein conserved in archaea (DUF2098) 3 91 1.4E-26 T 23-10-2018 IPR019209 Protein of unknown function DUF2098 Mlab_1743 491a3002eef8c2e5fcc0c0af4193ea3e 172 ProDom PD021915 UPF0254 MTH1148 HOMOLOG MJ1251 MK0012 4 148 3.0E-28 T 23-10-2018 IPR009625 Uncharacterised protein family UPF0254 Mlab_1743 491a3002eef8c2e5fcc0c0af4193ea3e 172 Hamap MF_00673 UPF0254 protein . 1 160 29.739 T 23-10-2018 IPR009625 Uncharacterised protein family UPF0254 Mlab_1743 491a3002eef8c2e5fcc0c0af4193ea3e 172 Pfam PF06787 Uncharacterised protein family (UPF0254) 1 159 3.2E-64 T 23-10-2018 IPR009625 Uncharacterised protein family UPF0254 Mlab_0670 1ab0e81cf8a905a80f1c4d5352be0046 369 SUPERFAMILY SSF101960 49 362 3.92E-73 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Mlab_0670 1ab0e81cf8a905a80f1c4d5352be0046 369 Pfam PF01458 Uncharacterized protein family (UPF0051) 120 342 6.0E-54 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Mlab_0797 50fa2063405c79114d7eb0f0c1562273 189 SUPERFAMILY SSF52218 1 188 4.66E-37 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0797 50fa2063405c79114d7eb0f0c1562273 189 Pfam PF03358 NADPH-dependent FMN reductase 3 157 5.0E-26 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Mlab_0797 50fa2063405c79114d7eb0f0c1562273 189 Gene3D G3DSA:3.40.50.360 4 188 3.8E-33 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1679 79ce89441b36ff1fac1f8a5a1e67db07 255 Pfam PF01694 Rhomboid family 67 220 2.5E-9 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 Mlab_1679 79ce89441b36ff1fac1f8a5a1e67db07 255 Gene3D G3DSA:1.20.1540.10 23 222 1.8E-6 T 23-10-2018 IPR035952 Rhomboid-like superfamily Mlab_1679 79ce89441b36ff1fac1f8a5a1e67db07 255 SUPERFAMILY SSF144091 24 220 7.85E-8 T 23-10-2018 Mlab_1445 07bb7ff7d09f6775d346f45b742e4ed7 172 Pfam PF03692 Putative zinc- or iron-chelating domain 13 104 7.3E-13 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein Mlab_0329 944126267a4e2ccd6d352503fdd8bdca 345 SUPERFAMILY SSF52540 9 168 1.73E-6 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0108 ebe671410e36978664ecc6e2f70aab41 257 Pfam PF07758 Protein of unknown function (DUF1614) 55 254 1.0E-50 T 23-10-2018 IPR011672 Protein of unknown function DUF1614 Mlab_1285 6098b918277daec54e7762dbc53f48ca 70 Pfam PF09947 Uncharacterized protein conserved in archaea (DUF2180) 1 67 4.0E-35 T 23-10-2018 IPR017211 Uncharacterised conserved protein UCP037465, zinc finger protein, AF1427 Mlab_1285 6098b918277daec54e7762dbc53f48ca 70 PIRSF PIRSF037465 1 70 1.7E-31 T 23-10-2018 IPR017211 Uncharacterised conserved protein UCP037465, zinc finger protein, AF1427 Mlab_0820 d1ed4e7efe2640ffa494e04a1435b0d0 293 Pfam PF03773 Predicted permease 10 290 1.1E-59 T 23-10-2018 IPR005524 Predicted permease DUF318 Mlab_0422 6f1481f1dcef3474d35195996d40bd44 111 Pfam PF13673 Acetyltransferase (GNAT) domain 8 99 1.6E-9 T 23-10-2018 IPR000182 GNAT domain Mlab_0422 6f1481f1dcef3474d35195996d40bd44 111 Gene3D G3DSA:3.40.630.30 1 110 1.0E-21 T 23-10-2018 Mlab_0422 6f1481f1dcef3474d35195996d40bd44 111 SUPERFAMILY SSF55729 2 99 2.87E-16 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase Mlab_1345 3920a96a000b357a5a334264a2166673 158 Gene3D G3DSA:3.30.70.640 1 157 1.0E-57 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1345 3920a96a000b357a5a334264a2166673 158 SUPERFAMILY SSF55040 12 156 1.23E-47 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1345 3920a96a000b357a5a334264a2166673 158 Pfam PF01967 MoaC family 15 155 3.3E-46 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1345 3920a96a000b357a5a334264a2166673 158 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 10 155 35.623 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 Mlab_1345 3920a96a000b357a5a334264a2166673 158 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 146 1.3E-50 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Mlab_1046 7c61978bf965e059ddfb3d4d22879960 187 Gene3D G3DSA:3.40.50.360 3 186 2.6E-41 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1046 7c61978bf965e059ddfb3d4d22879960 187 SUPERFAMILY SSF52218 5 187 2.24E-43 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_1046 7c61978bf965e059ddfb3d4d22879960 187 Pfam PF03358 NADPH-dependent FMN reductase 5 156 6.9E-26 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Mlab_0763 f7602b9ac827a32473a41ef61742f764 95 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 5.9E-16 T 23-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain Mlab_0763 f7602b9ac827a32473a41ef61742f764 95 Gene3D G3DSA:3.30.70.100 1 94 1.2E-28 T 23-10-2018 Mlab_0763 f7602b9ac827a32473a41ef61742f764 95 SUPERFAMILY SSF54909 1 89 2.23E-27 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel Mlab_0611 071b8fe3372730ab40b53c5f157ddb32 587 Pfam PF03553 Na+/H+ antiporter family 174 548 2.4E-51 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 Mlab_0780 551aff93a74e4e5796c608e2ef3bb7c4 286 Gene3D G3DSA:3.40.50.300 5 283 5.1E-20 T 23-10-2018 Mlab_0780 551aff93a74e4e5796c608e2ef3bb7c4 286 SUPERFAMILY SSF52540 9 251 4.49E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Mlab_0468 1e9870df51fd7d70029b3e66f4a2c5af 125 SUPERFAMILY SSF46785 50 114 7.0E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Mlab_0198 41b298a7d889d8503ef4ed4202cbcad3 144 Pfam PF01986 Domain of unknown function DUF123 26 118 1.0E-31 T 23-10-2018 IPR002837 Protein of unknown function DUF123 Mlab_1275 4ea391460b04d3baa038cf8d50b9d0f7 347 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 16 337 8.4E-59 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD Mlab_1275 4ea391460b04d3baa038cf8d50b9d0f7 347 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 10 325 1.4E-52 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD Mlab_0429 331a0c7561f992b3d15046973891785b 229 Pfam PF02596 Uncharacterised ArCR, COG2043 10 216 4.3E-61 T 23-10-2018 IPR003748 Protein of unknown function DUF169 Mlab_1367 bee8c033e50d9f43d2bf13508974b9eb 413 SUPERFAMILY SSF50998 56 373 3.81E-8 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Mlab_1250 6ed58456045a7b874b2b26a647d6966b 386 Pfam PF07790 Archaeal Type IV pilin, N-terminal 8 79 4.4E-6 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal Mlab_0877 975f107708a0100a83e4f52cc144fe95 420 Pfam PF01882 Protein of unknown function DUF58 188 238 2.9E-9 T 23-10-2018 IPR002881 Domain of unknown function DUF58 Mlab_0940 8f5d9f0090145a1c1599cbb3974adb08 308 Gene3D G3DSA:3.40.50.450 161 307 2.2E-8 T 23-10-2018 Mlab_0383 904cfaae3e277e95e1692eacea372e82 227 Pfam PF01930 Domain of unknown function DUF83 133 211 6.9E-7 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 Mlab_0406 6886755cb9bd59800d49336c654d8484 257 Pfam PF01863 Protein of unknown function DUF45 44 249 1.9E-45 T 23-10-2018 IPR002725 Protein of unknown function DUF45 Mlab_0406 6886755cb9bd59800d49336c654d8484 257 Gene3D G3DSA:3.30.2010.10 159 251 4.5E-16 T 23-10-2018 Mlab_1102 46662c3930331574f81baad1269b00f9 328 SUPERFAMILY SSF103481 206 303 7.06E-10 T 23-10-2018 Mlab_1102 46662c3930331574f81baad1269b00f9 328 Pfam PF00892 EamA-like transporter family 165 296 1.7E-9 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Mlab_0838 5a8dd952b6916420a2ab36565ef4f745 283 Pfam PF04018 Domain of unknown function (DUF368) 1 247 2.0E-55 T 23-10-2018 IPR007163 Protein of unknown function DUF368 Mlab_0924 a6d76e23c687a632e8071baf5819d21b 363 Pfam PF04981 NMD3 family 8 239 9.7E-49 T 23-10-2018 IPR007064 Nmd3, N-terminal Mlab_0351 d8c02d6249d6ebab789e8bf5ec72ac69 142 Gene3D G3DSA:3.40.50.360 1 139 1.0E-13 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0351 d8c02d6249d6ebab789e8bf5ec72ac69 142 SUPERFAMILY SSF52218 1 113 1.83E-12 T 23-10-2018 IPR029039 Flavoprotein-like superfamily Mlab_0328 430e066daf402a133bf2c5ca416e81f4 166 PIRSF PIRSF004897 1 166 1.3E-38 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type Mlab_1494 aac86d791d9992d30c69f38cfcbed34c 333 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 19 306 6.5E-24 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD Mlab_1494 aac86d791d9992d30c69f38cfcbed34c 333 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 12 299 3.8E-55 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD Mlab_0027 33e054c1418725bb179299d7af0eb0bb 255 Pfam PF02361 Cobalt transport protein 11 227 5.7E-32 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component Mlab_1667 d93f8823e16bab6b2dce1693cd3d8abf 190 Pfam PF11188 Protein of unknown function (DUF2975) 84 189 1.2E-8 T 23-10-2018 IPR021354 Protein of unknown function DUF2975 Mlab_0056 ae56f110145f5ca1f4b728cf714f5cc0 394 Pfam PF04412 Protein of unknown function (DUF521) 1 389 5.2E-143 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative Mlab_0130 d0cda4596acd007f58f7b2578a05b54d 189 SUPERFAMILY SSF52317 40 171 1.37E-7 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like Mlab_1309 a5fd8d0fff6aeb33f1469602919ede16 278 Pfam PF01889 Membrane protein of unknown function DUF63 14 278 8.9E-78 T 23-10-2018 IPR002749 Protein of unknown function DUF63 Mlab_1527 c1cf87c17be907e169dca89b226fe672 262 Pfam PF06541 Putative ABC-transporter type IV 10 175 5.3E-49 T 23-10-2018 IPR010540 Putative ABC-transporter type IV CmpB/TMEM229 Mlab_0885 9c7d7fff09462e7b615e107143e6c13c 113 Pfam PF01934 Protein of unknown function DUF86 11 104 4.7E-23 T 23-10-2018 IPR008201 Protein of unknown function DUF86 Mlab_0568 2644fa2757d49510bc220f4bcfdeaeee 285 Pfam PF00146 NADH dehydrogenase 4 274 1.6E-30 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Mlab_0256 cf722bd7ec20826421ef423dbef57345 234 Gene3D G3DSA:3.30.70.2200 1 154 7.3E-14 T 23-10-2018 Mlab_0563 f5eae82b045d23d253ef1eb96ea7b435 79 Pfam PF09881 Predicted membrane protein (DUF2108) 5 73 1.8E-23 T 23-10-2018 IPR019213 Protein of unknown function DUF2108, membrane Mlab_0562 d29cd5d463f4e722696597f897c0f430 79 Pfam PF09882 Predicted membrane protein (DUF2109) 3 78 3.0E-32 T 23-10-2018 IPR019214 Protein of unknown function DUF2109, membrane Mlab_0506 875a9d21478e0b5bbb30842193c3f9d7 227 Pfam PF14103 Domain of unknown function (DUF4276) 8 213 1.5E-45 T 23-10-2018 IPR025455 Protein of unknown function DUF4276 Mlab_0513 503cdfa51eecbe72215201d179b2ae73 232 Gene3D G3DSA:1.10.10.10 167 231 1.8E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Mlab_0236 3908ea413ec2fede3b628d69a94fa8a0 318 Gene3D G3DSA:3.30.70.2200 159 304 1.4E-23 T 23-10-2018 Mlab_0136 6710afffe5a21d9e5fc790d3c4976eb0 373 Pfam PF07790 Archaeal Type IV pilin, N-terminal 7 80 1.9E-6 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal