locus-tag	class	description
EHF32_00025	COG4585	Histidine kinase
EHF32_00045	COG0248	Ppx GppA phosphatase
EHF32_00050	COG1072	(Pantothenic acid kinase))
EHF32_00055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EHF32_00060	COG0736	holo-[acyl-carrier-protein] synthase activity
EHF32_00070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHF32_00075	COG0802	atpase or kinase
EHF32_00080	COG0456	acetyltransferase
EHF32_00080	COG1214	PFAM Peptidase M22, glycoprotease
EHF32_00090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHF32_00110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHF32_00145	COG0559	Belongs to the binding-protein-dependent transport system permease family
EHF32_00155	COG3548	integral membrane protein
EHF32_00160	COG0477	Major facilitator Superfamily
EHF32_00170	COG0516	GMP reductase activity
EHF32_00185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EHF32_00185	COG0519	Catalyzes the synthesis of GMP from XMP
EHF32_00200	COG0584	glycerophosphoryl diester phosphodiesterase
EHF32_00205	COG1131	(ABC) transporter
EHF32_00220	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EHF32_00225	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EHF32_00235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EHF32_00255	COG1793	dna ligase
EHF32_00270	COG0436	Aminotransferase
EHF32_00275	COG1309	transcriptional regulator
EHF32_00280	COG1233	COG1233 Phytoene dehydrogenase and related
EHF32_00285	COG0045	succinate-CoA ligase (ADP-forming) activity
EHF32_00300	COG2252	PERMEase
EHF32_00310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHF32_00315	COG0138	bifunctional purine biosynthesis protein purh
EHF32_00330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHF32_00335	COG1132	(ABC) transporter
EHF32_00340	COG1132	(ABC) transporter
EHF32_00345	COG3458	cephalosporin-C deacetylase activity
EHF32_00365	COG2838	Isocitrate dehydrogenase
EHF32_00385	COG1175	transmembrane transport
EHF32_00395	COG1940	carbohydrate kinase activity
EHF32_00400	COG0363	glucosamine-6-phosphate deaminase activity
EHF32_00405	COG0277	FAD linked oxidase domain protein
EHF32_00415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHF32_00425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHF32_00430	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHF32_00435	COG0402	S-adenosylhomocysteine deaminase activity
EHF32_00490	COG1175	transmembrane transport
EHF32_00520	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EHF32_00525	COG1132	(ABC) transporter
EHF32_00530	COG0477	Major facilitator Superfamily
EHF32_00540	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EHF32_00545	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHF32_00545	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHF32_00560	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EHF32_00575	COG2188	Transcriptional regulator
EHF32_00585	COG0180	Tryptophanyl-tRNA synthetase
EHF32_00600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHF32_00615	COG2009	succinate dehydrogenase
EHF32_00655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHF32_00670	COG0246	Mannitol dehydrogenase
EHF32_00675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHF32_00680	COG2213	PTS system mannitol-specific
EHF32_00685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHF32_00700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHF32_00705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHF32_00710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHF32_00725	COG4770	biotin carboxylase activity
EHF32_00730	COG0424	maF-like protein
EHF32_00735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHF32_00760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHF32_00810	COG1088	dTDP-glucose 4,6-dehydratase activity
EHF32_00815	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EHF32_00830	COG1215	transferase activity, transferring glycosyl groups
EHF32_00875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EHF32_00960	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHF32_00970	COG0714	Associated with various cellular activities
EHF32_00990	COG0745	RESPONSE REGULATOR receiver
EHF32_00995	COG5000	phosphorelay sensor kinase activity
EHF32_00995	COG5002	protein histidine kinase activity
EHF32_01000	COG5401	PFAM Sporulation and spore germination
EHF32_01005	COG1040	competence protein
EHF32_01025	COG0653	protein targeting
EHF32_01060	COG0489	protein tyrosine kinase activity
EHF32_01095	COG1595	DNA-templated transcription, initiation
EHF32_01105	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EHF32_01110	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EHF32_01115	COG0567	Dehydrogenase, E1 component
EHF32_01115	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHF32_01130	COG1253	flavin adenine dinucleotide binding
EHF32_01155	COG0011	TIGRFAM Protein of
EHF32_01160	COG2814	Major facilitator Superfamily
EHF32_01165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EHF32_01230	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EHF32_01255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHF32_01260	COG0601	transmembrane transport
EHF32_01300	COG1842	Phage shock protein A
EHF32_01315	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EHF32_01325	COG2076	Multidrug Resistance protein
EHF32_01345	COG0515	serine threonine protein kinase
EHF32_01345	COG2815	serine threonine protein kinase
EHF32_01360	COG1305	Transglutaminase-like
EHF32_01365	COG0018	arginyl-trna synthetase
EHF32_01375	COG0019	diaminopimelate decarboxylase activity
EHF32_01380	COG0460	homoserine dehydrogenase
EHF32_01390	COG0083	homoserine kinase activity
EHF32_01400	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHF32_01405	COG0154	amidase activity
EHF32_01410	COG1045	serine acetyltransferase
EHF32_01420	COG2890	protein-(glutamine-N5) methyltransferase activity
EHF32_01430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHF32_01440	COG0356	it plays a direct role in the translocation of protons across the membrane
EHF32_01450	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EHF32_01455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHF32_01460	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHF32_01465	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHF32_01470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHF32_01475	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EHF32_01480	COG3022	response to hydroperoxide
EHF32_01490	COG0631	protein serine/threonine phosphatase activity
EHF32_01495	COG1674	ftsk spoiiie
EHF32_01505	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHF32_01520	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHF32_01525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHF32_01530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EHF32_01545	COG1461	Dihydroxyacetone kinase
EHF32_01550	COG2376	Dihydroxyacetone kinase
EHF32_01560	COG0545	Peptidyl-prolyl cis-trans isomerase
EHF32_01565	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EHF32_01570	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHF32_01580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHF32_01585	COG0750	zinc metalloprotease
EHF32_01595	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHF32_01600	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EHF32_01610	COG1595	DNA-templated transcription, initiation
EHF32_01630	COG0442	prolyl-tRNA aminoacylation
EHF32_01660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHF32_01665	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHF32_01680	COG1194	a g-specific adenine glycosylase
EHF32_01690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHF32_01705	COG0196	riboflavin kinase activity
EHF32_01710	COG0477	Major facilitator Superfamily
EHF32_01725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EHF32_01745	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EHF32_01755	COG1175	transmembrane transport
EHF32_01760	COG0395	ABC-type sugar transport system, permease component
EHF32_01770	COG0673	inositol 2-dehydrogenase activity
EHF32_01800	COG0179	Fumarylacetoacetate (FAA) hydrolase
EHF32_01810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHF32_01820	COG0545	Peptidyl-prolyl cis-trans isomerase
EHF32_01840	COG1872	DUF167
EHF32_01845	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHF32_01855	COG0672	)-iron permease
EHF32_01860	COG2822	iron ion transport
EHF32_01865	COG2837	iron assimilation
EHF32_01870	COG3594	Acyltransferase
EHF32_01895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHF32_01895	COG0438	transferase activity, transferring glycosyl groups
EHF32_01905	COG4565	transcriptional regulatory protein
EHF32_01910	COG3290	protein histidine kinase activity
EHF32_01925	COG1185	polyribonucleotide nucleotidyltransferase activity
EHF32_01965	COG1090	epimerase
EHF32_01985	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EHF32_01995	COG4221	oxidoreductase activity
EHF32_02005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHF32_02010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHF32_02020	COG1674	ftsk spoiiie
EHF32_02030	COG1546	Belongs to the CinA family
EHF32_02030	COG1058	Belongs to the CinA family
EHF32_02035	COG1396	sequence-specific DNA binding
EHF32_02045	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHF32_02050	COG2137	regulation of response to DNA damage stimulus
EHF32_02055	COG2197	response regulator
EHF32_02055	COG3903	Transcriptional regulator
EHF32_02080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHF32_02085	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHF32_02090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHF32_02100	COG2813	Specifically methylates the guanine in position
EHF32_02105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHF32_02115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHF32_02125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHF32_02130	COG0131	Imidazoleglycerol-phosphate dehydratase
EHF32_02135	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHF32_02140	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHF32_02155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EHF32_02160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EHF32_02165	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EHF32_02170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHF32_02175	COG1126	abc transporter atp-binding protein
EHF32_02185	COG0765	amino acid transport
EHF32_02190	COG0765	amino acid transport
EHF32_02200	COG1122	ATPase activity
EHF32_02205	COG0183	Belongs to the thiolase family
EHF32_02215	COG1268	BioY protein
EHF32_02225	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHF32_02230	COG0072	phenylalanine-tRNA ligase activity
EHF32_02230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHF32_02240	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHF32_02245	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EHF32_02250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHF32_02255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EHF32_02260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHF32_02270	COG0165	Argininosuccinate lyase
EHF32_02275	COG2815	serine threonine protein kinase
EHF32_02275	COG0515	serine threonine protein kinase
EHF32_02340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHF32_02350	COG2267	carboxylic ester hydrolase activity
EHF32_02375	COG0647	UMP catabolic process
EHF32_02385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHF32_02390	COG0497	DNA recombination
EHF32_02395	COG0504	CTP synthase activity
EHF32_02410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHF32_02425	COG2234	aminopeptidase activity
EHF32_02435	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EHF32_02440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EHF32_02455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EHF32_02460	COG1160	GTP binding
EHF32_02520	COG2910	NAD(P)H-binding
EHF32_02525	COG0577	efflux transmembrane transporter activity
EHF32_02525	COG1136	(ABC) transporter
EHF32_02530	COG1136	(ABC) transporter
EHF32_02535	COG4585	Histidine kinase
EHF32_02550	COG1501	Belongs to the glycosyl hydrolase 31 family
EHF32_02560	COG2197	response regulator
EHF32_02565	COG3850	Histidine kinase
EHF32_02580	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHF32_02585	COG0352	thiamine-phosphate diphosphorylase activity
EHF32_02590	COG0351	phosphomethylpyrimidine kinase
EHF32_02590	COG0352	thiamine-phosphate diphosphorylase activity
EHF32_02590	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EHF32_02595	COG0577	efflux transmembrane transporter activity
EHF32_02595	COG1136	(ABC) transporter
EHF32_02600	COG1136	(ABC) transporter
EHF32_02600	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHF32_02605	COG0477	Major facilitator Superfamily
EHF32_02610	COG2197	response regulator
EHF32_02615	COG4585	Histidine kinase
EHF32_02620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHF32_02630	COG2197	response regulator
EHF32_02665	COG5002	protein histidine kinase activity
EHF32_02695	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EHF32_02700	COG1780	Probably involved in ribonucleotide reductase function
EHF32_02705	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHF32_02730	COG0667	Aldo Keto reductase
EHF32_02780	COG2372	response to copper ion
EHF32_02785	COG1716	ATPase activity
EHF32_02800	COG1192	Involved in chromosome partitioning
EHF32_02805	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EHF32_02825	COG1940	carbohydrate kinase activity
EHF32_02830	COG0204	Acyl-transferase
EHF32_02835	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EHF32_02840	COG0515	serine threonine protein kinase
EHF32_02840	COG2815	serine threonine protein kinase
EHF32_02845	COG3942	CHAP domain
EHF32_02845	COG1388	LysM domain
EHF32_02865	COG2001	Belongs to the MraZ family
EHF32_02870	COG0275	rRNA processing
EHF32_02880	COG0768	penicillin binding
EHF32_02890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHF32_02895	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHF32_02905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHF32_02915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHF32_02925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHF32_02935	COG1799	cell septum assembly
EHF32_02950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHF32_02970	COG0587	DNA-directed DNA polymerase activity
EHF32_02980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHF32_02985	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHF32_02990	COG0167	dihydroorotate dehydrogenase activity
EHF32_03000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHF32_03010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHF32_03015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHF32_03035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHF32_03040	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EHF32_03045	COG0723	plastoquinol--plastocyanin reductase activity
EHF32_03050	COG2010	Cytochrome c
EHF32_03055	COG1845	cytochrome c oxidase, subunit III
EHF32_03060	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHF32_03070	COG2807	transmembrane transport
EHF32_03075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHF32_03080	COG1796	DNA polymerase
EHF32_03080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHF32_03100	COG4129	membrane
EHF32_03110	COG2514	catechol 2,3-dioxygenase activity
EHF32_03115	COG3012	SEC-C Motif Domain Protein
EHF32_03125	COG2072	flavoprotein involved in K transport
EHF32_03135	COG0783	Belongs to the Dps family
EHF32_03140	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EHF32_03140	COG2755	lipolytic protein G-D-S-L family
EHF32_03165	COG0544	peptidyl-prolyl cis-trans isomerase activity
EHF32_03175	COG0740	serine-type endopeptidase activity
EHF32_03180	COG0740	serine-type endopeptidase activity
EHF32_03185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHF32_03205	COG0525	valine-tRNA ligase activity
EHF32_03220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHF32_03225	COG0285	dihydrofolate synthase activity
EHF32_03235	COG0105	UTP biosynthetic process
EHF32_03270	COG1530	ribonuclease E activity
EHF32_03280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EHF32_03285	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EHF32_03290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHF32_03295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHF32_03300	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHF32_03310	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHF32_03320	COG0799	negative regulation of ribosome biogenesis
EHF32_03335	COG1204	response to ionizing radiation
EHF32_03345	COG1204	response to ionizing radiation
EHF32_03405	COG1215	transferase activity, transferring glycosyl groups
EHF32_03410	COG1215	transferase activity, transferring glycosyl groups
EHF32_03415	COG3279	Response regulator of the LytR AlgR family
EHF32_03420	COG3290	protein histidine kinase activity
EHF32_03430	COG2135	peptidase activity
EHF32_03445	COG0512	Glutamine amidotransferase of anthranilate synthase
EHF32_03445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHF32_03450	COG0495	leucyl-tRNA aminoacylation
EHF32_03455	COG1555	photosystem II stabilization
EHF32_03470	COG0268	Binds directly to 16S ribosomal RNA
EHF32_03475	COG2267	carboxylic ester hydrolase activity
EHF32_03480	COG0481	GTPase activity
EHF32_03500	COG1420	regulation of RNA biosynthetic process
EHF32_03505	COG0484	heat shock protein binding
EHF32_03515	COG0537	adenosine 5'-monophosphoramidase activity
EHF32_03525	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHF32_03535	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHF32_03540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHF32_03550	COG1381	Involved in DNA repair and RecF pathway recombination
EHF32_03555	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHF32_03570	COG0386	Belongs to the glutathione peroxidase family
EHF32_03585	COG0358	DNA primase activity
EHF32_03590	COG4608	Belongs to the ABC transporter superfamily
EHF32_03600	COG2268	Band 7 protein
EHF32_03625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHF32_03650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHF32_03655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHF32_03670	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EHF32_03715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHF32_03725	COG1116	anion transmembrane transporter activity
EHF32_03765	COG0174	glutamine synthetase
EHF32_03770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EHF32_03785	COG2847	Copper chaperone PCu(A)C
EHF32_03790	COG2837	iron assimilation
EHF32_03805	COG0174	glutamine synthetase
EHF32_03825	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHF32_03830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHF32_03835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHF32_03845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHF32_03860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHF32_03865	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHF32_03875	COG0187	DNA topoisomerase II activity
EHF32_03880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHF32_03905	COG0756	dUTP diphosphatase activity
EHF32_03920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EHF32_03930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHF32_03935	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHF32_03935	COG1024	Enoyl-CoA hydratase
EHF32_03940	COG0183	Belongs to the thiolase family
EHF32_03975	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHF32_04030	COG2140	Oxalate decarboxylase
EHF32_04045	COG0601	transmembrane transport
EHF32_04065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHF32_04080	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHF32_04090	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EHF32_04095	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EHF32_04100	COG0217	transcriptional regulatory protein
EHF32_04105	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EHF32_04110	COG0632	four-way junction helicase activity
EHF32_04115	COG2255	four-way junction helicase activity
EHF32_04125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHF32_04130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHF32_04135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHF32_04145	COG1196	nuclear chromosome segregation
EHF32_04165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EHF32_04175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHF32_04180	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHF32_04185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHF32_04190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHF32_04195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHF32_04200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHF32_04205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHF32_04210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EHF32_04215	COG1309	transcriptional regulator
EHF32_04225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHF32_04230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHF32_04235	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EHF32_04245	COG3425	synthase
EHF32_04275	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EHF32_04280	COG0540	Belongs to the ATCase OTCase family
EHF32_04285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EHF32_04295	COG0505	Belongs to the CarA family
EHF32_04300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EHF32_04305	COG0284	orotidine-5'-phosphate decarboxylase activity
EHF32_04310	COG0194	GDP metabolic process
EHF32_04315	COG1758	RNA polymerase activity
EHF32_04320	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHF32_04330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHF32_04340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EHF32_04345	COG0140	phosphoribosyl-ATP diphosphatase activity
EHF32_04350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EHF32_04355	COG0107	imidazoleglycerol-phosphate synthase activity
EHF32_04360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EHF32_04375	COG0134	indole-3-glycerol-phosphate synthase activity
EHF32_04380	COG0133	tryptophan synthase activity
EHF32_04385	COG0159	tryptophan synthase activity
EHF32_04395	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHF32_04400	COG0069	glutamate synthase activity
EHF32_04400	COG0070	glutamate synthase
EHF32_04400	COG0067	glutamate synthase
EHF32_04425	COG2050	protein possibly involved in aromatic compounds catabolism
EHF32_04440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHF32_04475	COG0300	oxidoreductase activity
EHF32_04480	COG0584	glycerophosphoryl diester phosphodiesterase
EHF32_04500	COG0805	protein transport
EHF32_04505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHF32_04530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHF32_04540	COG1968	undecaprenyl-diphosphatase activity
EHF32_04545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHF32_04575	COG0406	alpha-ribazole phosphatase activity
EHF32_04610	COG0254	rRNA binding
EHF32_04615	COG1119	ATPase activity
EHF32_04620	COG0297	glycogen (starch) synthase activity
EHF32_04625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHF32_04630	COG0560	Phosphoserine phosphatase
EHF32_04640	COG1028	Short-chain dehydrogenase reductase Sdr
EHF32_04665	COG0488	(ABC) transporter
EHF32_04675	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHF32_04680	COG1120	ATPase activity
EHF32_04690	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EHF32_04695	COG2151	metal-sulfur cluster biosynthetic enzyme
EHF32_04700	COG0396	ATPase activity
EHF32_04720	COG1612	heme a metabolic process
EHF32_04730	COG0109	protoheme IX farnesyltransferase activity
EHF32_04740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHF32_04745	COG0166	Belongs to the GPI family
EHF32_04760	COG0363	glucosamine-6-phosphate deaminase activity
EHF32_04770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHF32_04775	COG0149	triose-phosphate isomerase activity
EHF32_04780	COG0126	phosphoglycerate kinase activity
EHF32_04790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EHF32_04795	COG1481	regulation of sporulation
EHF32_04800	COG1660	Displays ATPase and GTPase activities
EHF32_04805	COG0322	excinuclease ABC activity
EHF32_04815	COG1846	Transcriptional regulator
EHF32_04825	COG0556	nucleotide-excision repair
EHF32_04830	COG0237	dephospho-CoA kinase activity
EHF32_04840	COG2205	protein histidine kinase activity
EHF32_04840	COG0784	Response regulator, receiver
EHF32_04850	COG5002	protein histidine kinase activity
EHF32_04860	COG0539	negative regulation of cytoplasmic translation
EHF32_04865	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHF32_04890	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHF32_04895	COG0534	Mate efflux family protein
EHF32_04900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHF32_04920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHF32_04930	COG3507	Belongs to the glycosyl hydrolase 43 family
EHF32_04955	COG0328	RNA-DNA hybrid ribonuclease activity
EHF32_05000	COG1131	(ABC) transporter
EHF32_05010	COG4585	Histidine kinase
EHF32_05015	COG2197	response regulator
EHF32_05020	COG0668	transmembrane transport
EHF32_05040	COG1946	Acyl-CoA thioesterase
EHF32_05070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHF32_05090	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EHF32_05105	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EHF32_05125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHF32_05130	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHF32_05135	COG0154	amidase activity
EHF32_05140	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHF32_05145	COG0318	PFAM AMP-dependent synthetase and ligase
EHF32_05150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHF32_05155	COG0482	sulfurtransferase activity
EHF32_05170	COG0366	Alpha amylase catalytic
EHF32_05175	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EHF32_05180	COG3118	belongs to the thioredoxin family
EHF32_05220	COG0233	cytoplasmic translational termination
EHF32_05225	COG0528	UMP kinase activity
EHF32_05230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHF32_05235	COG0052	Belongs to the universal ribosomal protein uS2 family
EHF32_05250	COG4974	Belongs to the 'phage' integrase family
EHF32_05265	COG0792	nuclease activity
EHF32_05275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHF32_05280	COG0681	Belongs to the peptidase S26 family
EHF32_05285	COG0335	large ribosomal subunit rRNA binding
EHF32_05300	COG0336	Belongs to the RNA methyltransferase TrmD family
EHF32_05305	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHF32_05310	COG1837	Belongs to the UPF0109 family
EHF32_05315	COG0228	four-way junction DNA binding
EHF32_05320	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EHF32_05365	COG0552	protein localization to endoplasmic reticulum
EHF32_05370	COG1196	nuclear chromosome segregation
EHF32_05380	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EHF32_05385	COG0571	ribonuclease III activity
EHF32_05390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EHF32_05400	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHF32_05405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHF32_05410	COG0742	ribosomal rna small subunit methyltransferase
EHF32_05425	COG1181	Belongs to the D-alanine--D-alanine ligase family
EHF32_05430	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EHF32_05440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHF32_05445	COG0066	3-isopropylmalate dehydratase activity
EHF32_05450	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHF32_05455	COG2873	o-acetylhomoserine
EHF32_05465	COG0861	Integral membrane protein TerC family
EHF32_05520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHF32_05525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHF32_05525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHF32_05525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHF32_05530	COG1105	Belongs to the carbohydrate kinase PfkB family
EHF32_05535	COG1349	DNA-binding transcription factor activity
EHF32_05580	COG0531	amino acid
EHF32_05625	COG1120	ATPase activity
EHF32_05630	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHF32_05635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHF32_05640	COG4592	Periplasmic binding protein
EHF32_05650	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHF32_05655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHF32_05675	COG1120	ATPase activity
EHF32_05690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHF32_05695	COG0583	DNA-binding transcription factor activity
EHF32_05705	COG0477	Major facilitator Superfamily
EHF32_05710	COG0179	Fumarylacetoacetate (FAA) hydrolase
EHF32_05715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EHF32_05720	COG0473	3-isopropylmalate dehydrogenase activity
EHF32_05725	COG0477	Major facilitator Superfamily
EHF32_05750	COG1012	belongs to the aldehyde dehydrogenase family
EHF32_05750	COG1454	alcohol dehydrogenase
EHF32_05755	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHF32_05770	COG0129	dihydroxy-acid dehydratase activity
EHF32_05780	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EHF32_05800	COG2814	Major facilitator Superfamily
EHF32_05805	COG2409	Drug exporters of the RND superfamily
EHF32_05810	COG1309	transcriptional regulator
EHF32_05830	COG0483	inositol monophosphate 1-phosphatase activity
EHF32_05860	COG1028	Short-chain dehydrogenase reductase Sdr
EHF32_05880	COG1278	Cold shock
EHF32_05925	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHF32_05930	COG2177	Part of the ABC transporter FtsEX involved in
EHF32_05935	COG2884	Cell division ATP-binding protein ftsE
EHF32_05940	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EHF32_05950	COG0277	FAD linked oxidase domain protein
EHF32_05955	COG2116	formate transmembrane transporter activity
EHF32_05970	COG0789	Transcriptional regulator
EHF32_05985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EHF32_05990	COG1116	anion transmembrane transporter activity
EHF32_05995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHF32_06005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHF32_06105	COG0586	Pfam SNARE associated Golgi protein
EHF32_06110	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EHF32_06125	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHF32_06130	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHF32_06135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EHF32_06180	COG1215	transferase activity, transferring glycosyl groups
EHF32_06185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EHF32_06190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EHF32_06195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHF32_06205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHF32_06235	COG1233	COG1233 Phytoene dehydrogenase and related
EHF32_06255	COG1615	UPF0182 protein
EHF32_06260	COG3480	Lon protease (S16) C-terminal proteolytic domain
EHF32_06290	COG1074	ATP-dependent DNA helicase activity
EHF32_06315	COG0513	Belongs to the DEAD box helicase family
EHF32_06330	COG0006	proline dipeptidase activity
EHF32_06340	COG2239	Acts as a magnesium transporter
EHF32_06355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHF32_06375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHF32_06380	COG2171	N-acyltransferase activity
EHF32_06385	COG2326	polyphosphate kinase activity
EHF32_06390	COG1834	amidinotransferase
EHF32_06455	COG0747	negative chemotaxis
EHF32_06475	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHF32_06475	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHF32_06480	COG0509	glycine decarboxylation via glycine cleavage system
EHF32_06485	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EHF32_06500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHF32_06505	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EHF32_06520	COG1216	Glycosyl transferase, family 2
EHF32_06525	COG1132	(ABC) transporter
EHF32_06530	COG2814	Major facilitator Superfamily
EHF32_06540	COG3265	gluconokinase activity
EHF32_06545	COG1028	Short-chain dehydrogenase reductase Sdr
EHF32_06560	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EHF32_06605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHF32_06640	COG0583	DNA-binding transcription factor activity
EHF32_06650	COG0488	(ABC) transporter
EHF32_06670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EHF32_06710	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EHF32_06715	COG2197	response regulator
EHF32_06730	COG2272	Belongs to the type-B carboxylesterase lipase family
EHF32_06755	COG3708	Transcriptional regulator
EHF32_06755	COG2207	Transcriptional regulator
EHF32_06765	COG0012	GTP binding
EHF32_06770	COG2176	DNA-directed DNA polymerase activity
EHF32_06775	COG1322	Protein conserved in bacteria
EHF32_06800	COG0191	fructose-bisphosphate aldolase activity
EHF32_06805	COG1309	transcriptional regulator
EHF32_06815	COG2258	MOSC domain
EHF32_06825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHF32_06830	COG1570	exodeoxyribonuclease VII activity
EHF32_06835	COG1722	exodeoxyribonuclease VII activity
EHF32_06850	COG0114	fumarate hydratase activity
EHF32_06855	COG5002	protein histidine kinase activity
EHF32_06865	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EHF32_06890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHF32_06895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EHF32_06905	COG3214	Protein conserved in bacteria
EHF32_06910	COG1704	LemA family
EHF32_06950	COG1404	Belongs to the peptidase S8 family
EHF32_06965	COG0148	phosphopyruvate hydratase activity
EHF32_06985	COG0124	histidyl-tRNA synthetase
EHF32_06995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHF32_07000	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EHF32_07010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EHF32_07025	COG0193	aminoacyl-tRNA hydrolase activity
EHF32_07030	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EHF32_07035	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHF32_07045	COG1136	(ABC) transporter
EHF32_07055	COG0745	RESPONSE REGULATOR receiver
EHF32_07060	COG2205	protein histidine kinase activity
EHF32_07065	COG0166	Belongs to the GPI family
EHF32_07070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHF32_07070	COG1017	nitric oxide dioxygenase activity
EHF32_07085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHF32_07090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHF32_07110	COG1028	Short-chain dehydrogenase reductase Sdr
EHF32_07115	COG0488	(ABC) transporter
EHF32_07135	COG1174	glycine betaine transport
EHF32_07140	COG1125	glycine betaine transport
EHF32_07140	COG0517	IMP dehydrogenase activity
EHF32_07150	COG4552	Acetyltransferase involved in intracellular survival and related
EHF32_07155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHF32_07160	COG0667	Aldo Keto reductase
EHF32_07180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EHF32_07185	COG0477	Major facilitator Superfamily
EHF32_07190	COG0084	hydrolase, TatD family'
EHF32_07195	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHF32_07220	COG3833	ABC-type maltose transport systems, permease component
EHF32_07225	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EHF32_07245	COG1846	Transcriptional regulator
EHF32_07250	COG1331	Highly conserved protein containing a thioredoxin domain
EHF32_07255	COG2815	serine threonine protein kinase
EHF32_07255	COG0515	serine threonine protein kinase
EHF32_07265	COG0714	Associated with various cellular activities
EHF32_07295	COG1643	Atp-dependent helicase
EHF32_07315	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHF32_07325	COG4213	ABC transporter substrate-binding protein
EHF32_07335	COG1609	Transcriptional regulator
EHF32_07345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHF32_07370	COG0542	response to heat
EHF32_07390	COG2813	Specifically methylates the guanine in position
EHF32_07395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHF32_07425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHF32_07430	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHF32_07435	COG1780	Probably involved in ribonucleotide reductase function
EHF32_07450	COG0596	Alpha beta hydrolase
EHF32_07460	COG0667	Aldo Keto reductase
EHF32_07465	COG1937	Protein conserved in bacteria
EHF32_07470	COG2733	membrane
EHF32_07480	COG2062	phosphohistidine phosphatase, SixA
EHF32_07515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHF32_07520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EHF32_07535	COG1970	mechanosensitive ion channel activity
EHF32_07555	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHF32_07565	COG2197	response regulator
EHF32_07630	COG1214	PFAM Peptidase M22, glycoprotease
EHF32_07630	COG0456	acetyltransferase
EHF32_07640	COG1940	carbohydrate kinase activity
EHF32_07645	COG0657	acetylesterase activity
EHF32_07655	COG0747	negative chemotaxis
EHF32_07665	COG0444	Belongs to the ABC transporter superfamily
EHF32_07685	COG0667	Aldo Keto reductase
EHF32_07690	COG1309	transcriptional regulator
EHF32_07695	COG0300	oxidoreductase activity
EHF32_07715	COG0028	Belongs to the TPP enzyme family
EHF32_07745	COG0587	DNA-directed DNA polymerase activity
EHF32_07760	COG1335	isochorismatase
EHF32_07765	COG0697	spore germination
EHF32_07770	COG1846	Transcriptional regulator
EHF32_07800	COG1278	Cold shock
EHF32_07820	COG0745	RESPONSE REGULATOR receiver
EHF32_07825	COG5002	protein histidine kinase activity
EHF32_07835	COG0459	protein refolding
EHF32_07860	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHF32_07880	COG1846	Transcriptional regulator
EHF32_07920	COG3842	ATPase activity
EHF32_07930	COG2910	NAD(P)H-binding
EHF32_07935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHF32_07940	COG0215	cysteine-tRNA ligase activity
EHF32_07945	COG0697	spore germination
EHF32_07950	COG0454	-acetyltransferase
EHF32_07955	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHF32_07955	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EHF32_07960	COG1329	Transcriptional regulator
EHF32_07975	COG5002	protein histidine kinase activity
EHF32_07985	COG0588	phosphoglycerate mutase activity
EHF32_08005	COG4044	May play a role in the intracellular transport of hydrophobic ligands
EHF32_08015	COG0745	RESPONSE REGULATOR receiver
EHF32_08020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EHF32_08060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHF32_08105	COG0442	prolyl-tRNA aminoacylation
EHF32_08200	COG1335	isochorismatase
EHF32_08205	COG2409	Drug exporters of the RND superfamily
EHF32_08225	COG0470	DNA polymerase III
EHF32_08230	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHF32_08235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHF32_08235	COG1754	DNA topoisomerase type I activity
EHF32_08265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHF32_08285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHF32_08290	COG1408	metallophosphoesterase
EHF32_08315	COG1435	thymidine kinase activity
EHF32_08320	COG0579	oxidoreductase
EHF32_08330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHF32_08350	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHF32_08370	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHF32_08380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EHF32_08390	COG0714	Associated with various cellular activities
EHF32_08435	COG1028	Short-chain dehydrogenase reductase Sdr
EHF32_08440	COG0783	Belongs to the Dps family
EHF32_08445	COG3387	PFAM Glycoside hydrolase 15-related
EHF32_08455	COG1028	Short-chain dehydrogenase reductase Sdr
EHF32_08490	COG1609	Transcriptional regulator
EHF32_08510	COG1253	flavin adenine dinucleotide binding
EHF32_08520	COG1597	lipid kinase activity
EHF32_08530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHF32_08535	COG1271	oxidase subunit
EHF32_08540	COG1294	oxidase, subunit
EHF32_08545	COG4988	ABC transporter
EHF32_08550	COG4988	ABC transporter
EHF32_08595	COG0315	cyclic pyranopterin monophosphate synthase activity
EHF32_08615	COG0314	molybdopterin synthase activity
EHF32_08620	COG0315	cyclic pyranopterin monophosphate synthase activity
EHF32_08620	COG0521	Mo-molybdopterin cofactor biosynthetic process
EHF32_08625	COG0702	epimerase
EHF32_08635	COG2814	Major facilitator Superfamily
EHF32_08655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EHF32_08660	COG0395	ABC-type sugar transport system, permease component
EHF32_08665	COG1175	transmembrane transport
EHF32_08670	COG1653	transport
EHF32_08675	COG1609	Transcriptional regulator
EHF32_08680	COG0737	Belongs to the 5'-nucleotidase family
EHF32_08685	COG0222	ribosome binding
EHF32_08690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHF32_08715	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EHF32_08720	COG1233	COG1233 Phytoene dehydrogenase and related
EHF32_08730	COG4608	Belongs to the ABC transporter superfamily
EHF32_08745	COG0601	transmembrane transport
EHF32_08750	COG4166	transmembrane transport
EHF32_08760	COG0673	inositol 2-dehydrogenase activity
EHF32_08765	COG0673	inositol 2-dehydrogenase activity
EHF32_08775	COG1309	transcriptional regulator
EHF32_08795	COG1254	Belongs to the acylphosphatase family
EHF32_08800	COG0081	regulation of translation
EHF32_08805	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHF32_08850	COG0326	Molecular chaperone. Has ATPase activity
EHF32_08860	COG1012	belongs to the aldehyde dehydrogenase family
EHF32_08890	COG1609	Transcriptional regulator
EHF32_08900	COG0395	ABC-type sugar transport system, permease component
EHF32_08905	COG1175	transmembrane transport
EHF32_08920	COG3459	Glycosyltransferase 36 associated
EHF32_08920	COG3459	Glycosyltransferase 36 associated
EHF32_08925	COG1737	Transcriptional regulator
EHF32_08930	COG3639	organic phosphonate transmembrane transporter activity
EHF32_08940	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EHF32_08945	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EHF32_08980	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EHF32_08980	COG0778	Nitroreductase
EHF32_08985	COG0436	Aminotransferase
EHF32_09000	COG1881	PFAM PEBP family protein
EHF32_09015	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EHF32_09025	COG2030	dehydratase
EHF32_09035	COG0730	response to heat
EHF32_09055	COG1832	CoA-binding protein
EHF32_09080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHF32_09115	COG0395	ABC-type sugar transport system, permease component
EHF32_09140	COG0402	S-adenosylhomocysteine deaminase activity
EHF32_09155	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHF32_09230	COG1666	GTP binding
EHF32_09240	COG1595	DNA-templated transcription, initiation
EHF32_09245	COG1971	Probably functions as a manganese efflux pump
EHF32_09265	COG2226	methyltransferase
EHF32_09270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHF32_09275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EHF32_09305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EHF32_09315	COG4948	Mandelate Racemase Muconate Lactonizing
EHF32_09325	COG2409	Drug exporters of the RND superfamily
EHF32_09335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHF32_09340	COG1333	cytochrome c biogenesis protein
EHF32_09345	COG0785	Cytochrome C biogenesis protein
EHF32_09355	COG0406	alpha-ribazole phosphatase activity
EHF32_09370	COG0017	Asparaginyl-tRNA synthetase
EHF32_09390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHF32_09410	COG0640	Transcriptional regulator
EHF32_09415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHF32_09420	COG0569	domain protein
EHF32_09425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHF32_09435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHF32_09445	COG0037	tRNA processing
EHF32_09445	COG0590	tRNA wobble adenosine to inosine editing
EHF32_09450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHF32_09455	COG0598	Magnesium transport protein CorA
EHF32_09465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHF32_09465	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EHF32_09475	COG0667	Aldo Keto reductase
EHF32_09495	COG0419	ATPase involved in DNA repair
EHF32_09530	COG1501	Belongs to the glycosyl hydrolase 31 family
EHF32_09555	COG0745	RESPONSE REGULATOR receiver
EHF32_09575	COG1131	(ABC) transporter
EHF32_09585	COG0561	phosphatase activity
EHF32_09600	COG2197	response regulator
EHF32_09610	COG0259	pyridoxamine-phosphate oxidase activity
EHF32_09665	COG0318	PFAM AMP-dependent synthetase and ligase
EHF32_09670	COG0363	glucosamine-6-phosphate deaminase activity
EHF32_09685	COG1280	lysine exporter protein (LysE YggA)
EHF32_09730	COG1760	l-serine dehydratase
EHF32_09735	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHF32_09870	COG2017	converts alpha-aldose to the beta-anomer
EHF32_09875	COG2160	L-arabinose isomerase activity
EHF32_09905	COG0745	RESPONSE REGULATOR receiver
EHF32_09935	COG0101	tRNA pseudouridine synthase activity
EHF32_09945	COG0203	ribosomal protein L17
EHF32_09950	COG0202	RNA polymerase activity
EHF32_09955	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHF32_09960	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHF32_09965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EHF32_09970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHF32_09980	COG0024	Methionine aminopeptidase
EHF32_09985	COG0563	adenylate kinase activity
EHF32_09995	COG0200	Binds to the 23S rRNA
EHF32_10000	COG1841	ribosomal large subunit assembly
EHF32_10005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EHF32_10010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EHF32_10015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHF32_10020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHF32_10025	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHF32_10030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHF32_10035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHF32_10040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHF32_10045	COG0255	Belongs to the universal ribosomal protein uL29 family
EHF32_10050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EHF32_10055	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHF32_10060	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHF32_10065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHF32_10070	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHF32_10075	COG0089	rRNA binding
EHF32_10080	COG0088	Forms part of the polypeptide exit tunnel
EHF32_10085	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHF32_10090	COG0051	transcription antitermination factor activity, RNA binding
EHF32_10130	COG0438	transferase activity, transferring glycosyl groups
EHF32_10150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHF32_10155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHF32_10160	COG0049	tRNA binding
EHF32_10165	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EHF32_10200	COG2267	carboxylic ester hydrolase activity
EHF32_10205	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHF32_10210	COG0085	RNA polymerase activity
EHF32_10215	COG1984	allophanate hydrolase subunit 2
EHF32_10220	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EHF32_10250	COG1136	(ABC) transporter
EHF32_10250	COG0577	efflux transmembrane transporter activity
EHF32_10255	COG0577	efflux transmembrane transporter activity
EHF32_10255	COG1136	(ABC) transporter
EHF32_10260	COG2197	response regulator
EHF32_10265	COG4585	Histidine kinase
EHF32_10280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EHF32_10290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHF32_10295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHF32_10295	COG1116	anion transmembrane transporter activity
EHF32_10300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHF32_10310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHF32_10345	COG0488	(ABC) transporter
EHF32_10355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHF32_10360	COG0805	protein transport
EHF32_10380	COG1201	RNA secondary structure unwinding
EHF32_10385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EHF32_10405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EHF32_10405	COG0519	Catalyzes the synthesis of GMP from XMP
EHF32_10450	COG2357	RelA SpoT domain protein
EHF32_10455	COG1070	Carbohydrate kinase
EHF32_10460	COG2115	Belongs to the xylose isomerase family
EHF32_10475	COG1609	Transcriptional regulator
EHF32_10485	COG1175	transmembrane transport
EHF32_10500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHF32_10530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHF32_10545	COG0235	Class ii aldolase
EHF32_10565	COG4221	oxidoreductase activity
EHF32_10585	COG0738	Major facilitator superfamily
EHF32_10595	COG3634	alkyl hydroperoxide reductase activity
EHF32_10610	COG0494	nUDIX hydrolase
EHF32_10635	COG1595	DNA-templated transcription, initiation
EHF32_10640	COG1302	Protein conserved in bacteria
EHF32_10665	COG3237	CsbD-like
EHF32_10670	COG1929	Belongs to the glycerate kinase type-1 family
EHF32_10685	COG3979	chitinase
EHF32_10695	COG3507	Belongs to the glycosyl hydrolase 43 family
EHF32_10705	COG4214	carbohydrate transport
EHF32_10710	COG1129	ABC transporter
EHF32_10715	COG4213	ABC transporter substrate-binding protein
EHF32_10740	COG3458	cephalosporin-C deacetylase activity
EHF32_10750	COG1609	Transcriptional regulator
EHF32_10760	COG1175	transmembrane transport
EHF32_10790	COG0745	RESPONSE REGULATOR receiver
EHF32_10795	COG2205	protein histidine kinase activity
EHF32_10815	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHF32_10840	COG0667	Aldo Keto reductase
EHF32_10945	COG0039	L-malate dehydrogenase activity
EHF32_10960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHF32_10965	COG0601	transmembrane transport
EHF32_10995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHF32_11010	COG1129	ABC transporter
EHF32_11015	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EHF32_11040	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHF32_11080	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHF32_11085	COG0542	response to heat
EHF32_11095	COG3655	Transcriptional regulator
EHF32_11125	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EHF32_11130	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHF32_11155	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHF32_11160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHF32_11165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHF32_11170	COG0302	gtp cyclohydrolase
EHF32_11175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHF32_11185	COG0037	tRNA processing
EHF32_11190	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EHF32_11215	COG4974	Belongs to the 'phage' integrase family
EHF32_11305	COG1401	restriction endodeoxyribonuclease activity
EHF32_11335	COG0667	Aldo Keto reductase
EHF32_11365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHF32_11375	COG0463	Glycosyl transferase, family 2
EHF32_11415	COG0039	L-malate dehydrogenase activity
EHF32_11430	COG2818	Glycosylase
EHF32_11485	COG1122	ATPase activity
EHF32_11490	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHF32_11505	COG1960	acyl-CoA dehydrogenase activity
EHF32_11525	COG0513	Belongs to the DEAD box helicase family
EHF32_11530	COG2017	converts alpha-aldose to the beta-anomer
EHF32_11540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHF32_11545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHF32_11550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHF32_11565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHF32_11575	COG1695	Transcriptional regulator
EHF32_11595	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EHF32_11620	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EHF32_11625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHF32_11645	COG0151	Belongs to the GarS family
EHF32_11675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EHF32_11680	COG2233	PERMEase
EHF32_11690	COG2723	6-phospho-beta-galactosidase activity
EHF32_11695	COG0395	ABC-type sugar transport system, permease component
EHF32_11710	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHF32_11715	COG0047	phosphoribosylformylglycinamidine synthase activity
EHF32_11720	COG1131	(ABC) transporter
EHF32_11730	COG4585	Histidine kinase
EHF32_11735	COG2197	response regulator
EHF32_11745	COG1120	ATPase activity
EHF32_11750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHF32_11760	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EHF32_11775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHF32_11795	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EHF32_11795	COG3608	succinylglutamate desuccinylase aspartoacylase
EHF32_11800	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EHF32_11805	COG0604	alcohol dehydrogenase
EHF32_11805	COG3321	synthase
EHF32_11805	COG1028	Short-chain dehydrogenase reductase Sdr
EHF32_11825	COG2080	2 iron, 2 sulfur cluster binding
EHF32_11825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EHF32_11835	COG0402	S-adenosylhomocysteine deaminase activity
EHF32_11840	COG1012	belongs to the aldehyde dehydrogenase family
EHF32_11870	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHF32_11880	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHF32_11885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHF32_11895	COG1116	anion transmembrane transporter activity
EHF32_11900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHF32_11910	COG0402	S-adenosylhomocysteine deaminase activity
EHF32_11920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHF32_11945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EHF32_11960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EHF32_11970	COG2351	hydroxyisourate hydrolase activity
EHF32_12050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHF32_12055	COG0366	Alpha amylase catalytic
EHF32_12060	COG1473	amidohydrolase
EHF32_12090	COG0531	amino acid
EHF32_12105	COG0513	Belongs to the DEAD box helicase family
EHF32_12125	COG1690	Belongs to the RtcB family
EHF32_12130	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHF32_12155	COG2113	Glycine betaine
EHF32_12160	COG4176	ABC-type proline glycine betaine transport system permease component
EHF32_12165	COG0517	IMP dehydrogenase activity
EHF32_12165	COG4175	Glycine betaine
EHF32_12180	COG1131	(ABC) transporter
EHF32_12190	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EHF32_12200	COG0628	permease
EHF32_12210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHF32_12225	COG0601	transmembrane transport
EHF32_12260	COG1309	transcriptional regulator
EHF32_12280	COG0702	epimerase
EHF32_12285	COG1733	regulation of RNA biosynthetic process
EHF32_12300	COG1320	monovalent cation:proton antiporter activity
EHF32_12305	COG2212	antiporter activity
EHF32_12325	COG2111	Na H antiporter
EHF32_12325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EHF32_12330	COG1609	Transcriptional regulator
EHF32_12335	COG0738	Major facilitator superfamily
EHF32_12340	COG2197	response regulator
EHF32_12355	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EHF32_12365	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EHF32_12365	COG0392	lysyltransferase activity
EHF32_12370	COG1278	Cold shock
EHF32_12375	COG1802	Transcriptional regulator
EHF32_12390	COG2197	response regulator
EHF32_12405	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHF32_12410	COG1869	D-ribose catabolic process
EHF32_12415	COG1129	ABC transporter
EHF32_12425	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHF32_12430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHF32_12440	COG1716	ATPase activity
EHF32_12445	COG1716	ATPase activity
EHF32_12460	COG0768	penicillin binding
EHF32_12470	COG2815	serine threonine protein kinase
EHF32_12470	COG0515	serine threonine protein kinase
EHF32_12490	COG0705	Rhomboid family
EHF32_12515	COG1051	belongs to the nudix hydrolase family
EHF32_12550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHF32_12555	COG0187	DNA topoisomerase II activity
EHF32_12560	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
EHF32_12565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHF32_12570	COG0592	DNA-directed DNA polymerase activity
EHF32_12575	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHF32_12580	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EHF32_12585	COG0594	ribonuclease P activity
EHF32_12590	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EHF32_12595	COG0706	membrane insertase activity
EHF32_12605	COG0357	Ribosomal RNA small subunit methyltransferase G
EHF32_12610	COG1192	Involved in chromosome partitioning
EHF32_12625	COG3118	belongs to the thioredoxin family
EHF32_12630	COG0492	ferredoxin-NADP+ reductase activity
EHF32_12645	COG2890	protein-(glutamine-N5) methyltransferase activity
EHF32_12650	COG0617	tRNA 3'-terminal CCA addition
EHF32_12655	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHF32_12660	COG1733	regulation of RNA biosynthetic process
EHF32_12680	COG1012	belongs to the aldehyde dehydrogenase family
EHF32_12700	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EHF32_12705	COG1228	amidohydrolase
EHF32_12720	COG0765	amino acid transport
EHF32_12740	COG0360	Binds together with S18 to 16S ribosomal RNA
EHF32_12750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EHF32_12755	COG0359	binds to the 23S rRNA
EHF32_12780	COG0305	Participates in initiation and elongation during chromosome replication
EHF32_12820	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EHF32_12825	COG1609	Transcriptional regulator
EHF32_12830	COG1609	Transcriptional regulator
EHF32_12840	COG0601	transmembrane transport
EHF32_12850	COG0444	Belongs to the ABC transporter superfamily
EHF32_12855	COG4608	Belongs to the ABC transporter superfamily
EHF32_12860	COG1621	beta-fructofuranosidase activity
EHF32_12865	COG1621	beta-fructofuranosidase activity
EHF32_12900	COG2197	response regulator
EHF32_12935	COG0697	spore germination
EHF32_12940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHF32_12960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHF32_12975	COG1950	PFAM Membrane protein of
EHF32_12980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHF32_12990	COG0022	dehydrogenase e1 component
EHF32_12995	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHF32_13000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHF32_13010	COG1121	(ABC) transporter
EHF32_13025	COG0701	Predicted permease
EHF32_13040	COG2094	Belongs to the DNA glycosylase MPG family
EHF32_13050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EHF32_13055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EHF32_13060	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHF32_13065	COG0776	regulation of translation
EHF32_13070	COG3336	cytochrome c oxidase
EHF32_13080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EHF32_13085	COG5398	heme oxygenase
EHF32_13110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHF32_13120	COG0667	Aldo Keto reductase
EHF32_13125	COG1349	DNA-binding transcription factor activity
EHF32_13130	COG0747	negative chemotaxis
EHF32_13140	COG0444	Belongs to the ABC transporter superfamily
EHF32_13145	COG4608	Belongs to the ABC transporter superfamily
EHF32_13150	COG2267	carboxylic ester hydrolase activity
EHF32_13175	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EHF32_13180	COG0477	Major facilitator Superfamily
EHF32_13200	COG0717	Belongs to the dCTP deaminase family
EHF32_13205	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EHF32_13210	COG2205	protein histidine kinase activity
EHF32_13220	COG2153	protein acetylation
EHF32_13235	COG0443	Heat shock 70 kDa protein
EHF32_13240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHF32_13245	COG0484	heat shock protein binding
EHF32_13250	COG0789	Transcriptional regulator
EHF32_13275	COG2188	Transcriptional regulator
EHF32_13290	COG1175	transmembrane transport
EHF32_13295	COG0395	ABC-type sugar transport system, permease component
EHF32_13300	COG0300	oxidoreductase activity
EHF32_13305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHF32_13310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHF32_13345	COG0438	transferase activity, transferring glycosyl groups
EHF32_13375	COG0542	response to heat
EHF32_13390	COG2197	response regulator
EHF32_13435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHF32_13445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EHF32_13450	COG3387	PFAM Glycoside hydrolase 15-related
EHF32_13460	COG4152	abc transporter atp-binding protein
EHF32_13465	COG2197	response regulator
EHF32_13470	COG4585	Histidine kinase
EHF32_13545	COG2205	protein histidine kinase activity
EHF32_13550	COG0745	RESPONSE REGULATOR receiver
EHF32_13565	COG0534	Mate efflux family protein
EHF32_13570	COG3590	peptidase
EHF32_13595	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHF32_13610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHF32_13615	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EHF32_13620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EHF32_13640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EHF32_13650	COG1937	Protein conserved in bacteria
EHF32_13660	COG1846	Transcriptional regulator
EHF32_13665	COG3340	Belongs to the peptidase S51 family
EHF32_13675	COG0318	PFAM AMP-dependent synthetase and ligase
EHF32_13680	COG0477	Major facilitator Superfamily
EHF32_13690	COG0789	Transcriptional regulator
EHF32_13720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EHF32_13750	COG2186	Transcriptional regulator
EHF32_13755	COG0302	gtp cyclohydrolase
EHF32_13765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EHF32_13775	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EHF32_13790	COG1012	belongs to the aldehyde dehydrogenase family
EHF32_13800	COG1082	Xylose isomerase domain protein TIM barrel
EHF32_13820	COG1012	belongs to the aldehyde dehydrogenase family
EHF32_13825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHF32_13825	COG1116	anion transmembrane transporter activity
EHF32_13830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHF32_13835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHF32_13860	COG1012	belongs to the aldehyde dehydrogenase family
EHF32_13885	COG0411	ABC transporter
EHF32_13910	COG1028	Short-chain dehydrogenase reductase Sdr
EHF32_13925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHF32_13930	COG1116	anion transmembrane transporter activity
EHF32_13930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHF32_13980	COG1960	acyl-CoA dehydrogenase activity
EHF32_14005	COG2807	transmembrane transport
EHF32_14025	COG3485	protocatechuate 3,4-dioxygenase
EHF32_14040	COG2267	carboxylic ester hydrolase activity
EHF32_14045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHF32_14050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EHF32_14075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EHF32_14080	COG0183	Belongs to the thiolase family
EHF32_14085	COG1414	Transcriptional regulator
EHF32_14090	COG3104	oligopeptide transport
EHF32_14140	COG0697	spore germination
EHF32_14145	COG0583	DNA-binding transcription factor activity
EHF32_14150	COG1674	ftsk spoiiie
EHF32_14175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHF32_14190	COG0181	hydroxymethylbilane synthase activity
EHF32_14220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EHF32_14225	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHF32_14245	COG0423	glycine-tRNA ligase activity
EHF32_14290	COG1404	Belongs to the peptidase S8 family
EHF32_14310	COG1404	Belongs to the peptidase S8 family
EHF32_14315	COG1404	Belongs to the peptidase S8 family
EHF32_14355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHF32_14360	COG2072	flavoprotein involved in K transport
EHF32_14365	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EHF32_14380	COG1131	(ABC) transporter
EHF32_14385	COG1024	Enoyl-CoA hydratase
EHF32_14400	COG0484	heat shock protein binding
EHF32_14405	COG0471	metal ion transport
EHF32_14405	COG0490	domain, Protein
EHF32_14420	COG4172	Belongs to the ABC transporter superfamily
EHF32_14425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHF32_14450	COG0563	adenylate kinase activity
EHF32_14455	COG0561	phosphatase activity
EHF32_14465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHF32_14465	COG2190	(PTS) system
EHF32_14465	COG1263	PTS System
EHF32_14475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EHF32_14495	COG2079	MmgE PrpD family protein
EHF32_14500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHF32_14510	COG0183	Belongs to the thiolase family
EHF32_14515	COG1024	Enoyl-CoA hydratase
EHF32_14525	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EHF32_14545	COG1012	belongs to the aldehyde dehydrogenase family
EHF32_14550	COG0477	Major facilitator Superfamily
EHF32_14555	COG0667	Aldo Keto reductase
EHF32_14560	COG1834	amidinotransferase
EHF32_14565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EHF32_14580	COG1305	Transglutaminase-like
EHF32_14585	COG0477	Major facilitator Superfamily
EHF32_14605	COG0095	Lipoate-protein ligase
EHF32_14610	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EHF32_14620	COG1309	transcriptional regulator
EHF32_14635	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHF32_14645	COG1609	Transcriptional regulator
EHF32_14655	COG0395	ABC-type sugar transport system, permease component
EHF32_14685	COG3534	alpha-L-arabinofuranosidase
EHF32_14690	COG1653	transport
EHF32_14720	COG0077	Prephenate dehydratase
EHF32_14725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHF32_14735	COG0415	Belongs to the DNA photolyase family
EHF32_14740	COG1597	lipid kinase activity
EHF32_14745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHF32_14750	COG0561	phosphatase activity
EHF32_14770	COG0577	efflux transmembrane transporter activity
EHF32_14770	COG1136	(ABC) transporter
EHF32_14790	COG0745	RESPONSE REGULATOR receiver
EHF32_14795	COG5002	protein histidine kinase activity
EHF32_14800	COG1316	TRANSCRIPTIONal
EHF32_14805	COG1316	TRANSCRIPTIONal
EHF32_14830	COG2354	Protein conserved in bacteria
EHF32_14860	COG3290	protein histidine kinase activity
EHF32_14865	COG4565	transcriptional regulatory protein
EHF32_14870	COG0076	glutamate decarboxylase activity
EHF32_14890	COG1136	(ABC) transporter
EHF32_14910	COG0477	Major facilitator Superfamily
EHF32_14950	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EHF32_14955	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EHF32_14960	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EHF32_14975	COG1764	response to oxidative stress
EHF32_14980	COG1846	Transcriptional regulator
EHF32_15005	COG2011	ABC-type metal ion transport system permease component
EHF32_15010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHF32_15035	COG5002	protein histidine kinase activity
EHF32_15050	COG0861	Integral membrane protein TerC family
EHF32_15095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EHF32_15165	COG0395	ABC-type sugar transport system, permease component
EHF32_15205	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EHF32_15215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHF32_15230	COG0346	lactoylglutathione lyase activity
EHF32_15285	COG0659	secondary active sulfate transmembrane transporter activity
EHF32_15300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EHF32_15315	COG1120	ATPase activity
EHF32_15320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHF32_15325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHF32_15330	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHF32_15370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EHF32_15375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHF32_15385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EHF32_15390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHF32_15430	COG2211	Major facilitator Superfamily
EHF32_15440	COG2197	response regulator
EHF32_15445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHF32_15450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHF32_15455	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHF32_15460	COG1120	ATPase activity
EHF32_15480	COG0489	protein tyrosine kinase activity
EHF32_15500	COG1136	(ABC) transporter
EHF32_15500	COG0577	efflux transmembrane transporter activity
EHF32_15505	COG0577	efflux transmembrane transporter activity
EHF32_15510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHF32_15525	COG2205	protein histidine kinase activity
EHF32_15540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHF32_15550	COG2837	iron assimilation
EHF32_15560	COG5295	Hep Hag repeat protein
EHF32_15560	COG4932	domain protein
EHF32_15565	COG2909	trisaccharide binding
EHF32_15585	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHF32_15590	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EHF32_15595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHF32_15600	COG4585	Histidine kinase
EHF32_15615	COG0248	Ppx GppA phosphatase
EHF32_15620	COG1072	(Pantothenic acid kinase))
EHF32_15625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EHF32_15630	COG0736	holo-[acyl-carrier-protein] synthase activity
EHF32_15645	COG0802	atpase or kinase
EHF32_15650	COG1214	PFAM Peptidase M22, glycoprotease
EHF32_15650	COG0456	acetyltransferase
EHF32_15660	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction