locus-tag	class	description
Mag101_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Mag101_00010	COG0592	DNA-directed DNA polymerase activity
Mag101_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Mag101_00035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Mag101_00040	COG1404	Belongs to the peptidase S8 family
Mag101_00050	COG0751	glycine-tRNA ligase activity
Mag101_00055	COG0752	glycyl-tRNA synthetase alpha subunit
Mag101_00070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Mag101_00075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Mag101_00080	COG0569	domain protein
Mag101_00090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Mag101_00095	COG0242	peptide deformylase activity
Mag101_00100	COG1652	LysM domain
Mag101_00105	COG0758	DNA mediated transformation
Mag101_00115	COG0009	L-threonylcarbamoyladenylate synthase
Mag101_00130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Mag101_00135	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Mag101_00140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Mag101_00155	COG2235	arginine
Mag101_00175	COG0531	amino acid
Mag101_00180	COG4771	TonB-dependent receptor
Mag101_00185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Mag101_00195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Mag101_00220	COG0534	Mate efflux family protein
Mag101_00225	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Mag101_00225	COG1565	acr, cog1565
Mag101_00230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Mag101_00235	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Mag101_00260	COG1612	heme a metabolic process
Mag101_00265	COG0109	protoheme IX farnesyltransferase activity
Mag101_00285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Mag101_00310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Mag101_00350	COG2234	aminopeptidase activity
Mag101_00360	COG0720	synthase
Mag101_00375	COG3590	peptidase
Mag101_00400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Mag101_00405	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_00410	COG2271	Major facilitator Superfamily
Mag101_00435	COG2186	Transcriptional regulator
Mag101_00455	COG1842	Phage shock protein A
Mag101_00465	COG2268	Band 7 protein
Mag101_00485	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Mag101_00490	COG1215	transferase activity, transferring glycosyl groups
Mag101_00495	COG0438	transferase activity, transferring glycosyl groups
Mag101_00510	COG0438	transferase activity, transferring glycosyl groups
Mag101_00515	COG0438	transferase activity, transferring glycosyl groups
Mag101_00530	COG0438	transferase activity, transferring glycosyl groups
Mag101_00540	COG0457	Tetratricopeptide repeat
Mag101_00550	COG1696	Membrane protein involved in D-alanine export
Mag101_00595	COG0346	lactoylglutathione lyase activity
Mag101_00615	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_00645	COG0129	dihydroxy-acid dehydratase activity
Mag101_00650	COG1012	belongs to the aldehyde dehydrogenase family
Mag101_00665	COG1609	Transcriptional regulator
Mag101_00690	COG2814	Major facilitator Superfamily
Mag101_00695	COG0673	inositol 2-dehydrogenase activity
Mag101_00700	COG2207	Transcriptional regulator
Mag101_00700	COG4753	response regulator
Mag101_00745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Mag101_00755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Mag101_00780	COG2723	6-phospho-beta-galactosidase activity
Mag101_00785	COG2211	Major facilitator Superfamily
Mag101_00795	COG2115	Belongs to the xylose isomerase family
Mag101_00800	COG1070	Carbohydrate kinase
Mag101_00820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Mag101_00825	COG0601	transmembrane transport
Mag101_00845	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Mag101_00860	COG0583	DNA-binding transcription factor activity
Mag101_00865	COG1233	COG1233 Phytoene dehydrogenase and related
Mag101_00905	COG0076	glutamate decarboxylase activity
Mag101_00910	COG3486	L-lysine 6-monooxygenase (NADPH) activity
Mag101_00935	COG0523	cobalamin synthesis protein
Mag101_00975	COG0210	DNA helicase
Mag101_00985	COG1671	Belongs to the UPF0178 family
Mag101_01000	COG0415	Belongs to the DNA photolyase family
Mag101_01010	COG0606	chelatase, subunit chli
Mag101_01025	COG0347	Belongs to the P(II) protein family
Mag101_01030	COG0004	ammonium transporteR
Mag101_01035	COG0347	Belongs to the P(II) protein family
Mag101_01050	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Mag101_01065	COG1965	Belongs to the frataxin family
Mag101_01075	COG0165	Argininosuccinate lyase
Mag101_01080	COG2972	Histidine kinase
Mag101_01080	COG0745	RESPONSE REGULATOR receiver
Mag101_01095	COG1280	lysine exporter protein (LysE YggA)
Mag101_01100	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_01140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Mag101_01145	COG2813	Specifically methylates the guanine in position
Mag101_01145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Mag101_01160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Mag101_01180	COG0724	RNA recognition motif
Mag101_01185	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Mag101_01240	COG2862	Uncharacterized protein family, UPF0114
Mag101_01260	COG0583	DNA-binding transcription factor activity
Mag101_01300	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Mag101_01305	COG1678	Uncharacterized ACR, COG1678
Mag101_01335	COG0840	transmembrane signaling receptor activity
Mag101_01380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Mag101_01385	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Mag101_01390	COG0070	glutamate synthase
Mag101_01390	COG0067	glutamate synthase
Mag101_01390	COG0069	glutamate synthase activity
Mag101_01395	COG0493	'glutamate synthase
Mag101_01400	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Mag101_01405	COG2199	diguanylate cyclase activity
Mag101_01405	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Mag101_01415	COG0688	phosphatidylethanolamine metabolic process
Mag101_01425	COG1162	GTPase activity
Mag101_01430	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Mag101_01440	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Mag101_01440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Mag101_01445	COG0802	atpase or kinase
Mag101_01455	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Mag101_01465	COG1923	regulation of RNA biosynthetic process
Mag101_01470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Mag101_01475	COG0330	HflC and HflK could
Mag101_01480	COG0330	HflC and HflK could
Mag101_01490	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Mag101_01495	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Mag101_01500	COG1272	protein, Hemolysin III
Mag101_01505	COG2951	lytic endotransglycosylase activity
Mag101_01510	COG2814	Major facilitator Superfamily
Mag101_01610	COG3501	Rhs element vgr protein
Mag101_01620	COG2815	serine threonine protein kinase
Mag101_01620	COG0515	serine threonine protein kinase
Mag101_01640	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Mag101_01650	COG0557	exoribonuclease II activity
Mag101_01655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Mag101_01690	COG0360	Binds together with S18 to 16S ribosomal RNA
Mag101_01695	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Mag101_01705	COG0359	binds to the 23S rRNA
Mag101_01710	COG0305	Participates in initiation and elongation during chromosome replication
Mag101_01725	COG1960	acyl-CoA dehydrogenase activity
Mag101_01745	COG3275	phosphorelay sensor kinase activity
Mag101_01775	COG4771	TonB-dependent receptor
Mag101_01780	COG0457	Tetratricopeptide repeat
Mag101_01785	COG0308	aminopeptidase N
Mag101_01800	COG0463	Glycosyl transferase, family 2
Mag101_01805	COG0346	lactoylglutathione lyase activity
Mag101_01820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Mag101_01830	COG1012	belongs to the aldehyde dehydrogenase family
Mag101_01850	COG3264	Mechanosensitive ion channel
Mag101_01850	COG1196	nuclear chromosome segregation
Mag101_01885	COG3479	Phenolic acid decarboxylase
Mag101_01890	COG2267	carboxylic ester hydrolase activity
Mag101_01930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Mag101_01935	COG2814	Major facilitator Superfamily
Mag101_01970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Mag101_01975	COG0358	DNA primase activity
Mag101_01980	COG1610	YqeY-like protein
Mag101_01985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Mag101_01990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Mag101_01995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Mag101_02000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Mag101_02015	COG2205	protein histidine kinase activity
Mag101_02020	COG0745	RESPONSE REGULATOR receiver
Mag101_02040	COG0617	tRNA 3'-terminal CCA addition
Mag101_02045	COG0745	RESPONSE REGULATOR receiver
Mag101_02050	COG2719	SpoVR family
Mag101_02055	COG2718	Belongs to the UPF0229 family
Mag101_02060	COG2766	serine protein kinase
Mag101_02065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Mag101_02075	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Mag101_02080	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Mag101_02090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Mag101_02095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Mag101_02100	COG3178	'Phosphotransferase
Mag101_02105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Mag101_02110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Mag101_02125	COG0512	Glutamine amidotransferase of anthranilate synthase
Mag101_02130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Mag101_02135	COG0134	indole-3-glycerol-phosphate synthase activity
Mag101_02140	COG0457	Tetratricopeptide repeat
Mag101_02160	COG1765	OsmC-like protein
Mag101_02170	COG1012	belongs to the aldehyde dehydrogenase family
Mag101_02185	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Mag101_02225	COG2252	PERMEase
Mag101_02240	COG1132	(ABC) transporter
Mag101_02275	COG2111	Na H antiporter
Mag101_02280	COG1006	Multisubunit Na H antiporter MnhC subunit
Mag101_02290	COG1863	multisubunit Na H antiporter MnhE subunit
Mag101_02295	COG2212	antiporter activity
Mag101_02300	COG1320	monovalent cation:proton antiporter activity
Mag101_02310	COG0515	serine threonine protein kinase
Mag101_02310	COG2815	serine threonine protein kinase
Mag101_02315	COG2885	chlorophyll binding
Mag101_02315	COG3047	cAMP biosynthetic process
Mag101_02340	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Mag101_02345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Mag101_02350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Mag101_02375	COG0006	proline dipeptidase activity
Mag101_02380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Mag101_02385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Mag101_02390	COG0705	Rhomboid family
Mag101_02395	COG1253	flavin adenine dinucleotide binding
Mag101_02400	COG3273	potassium ion transport
Mag101_02400	COG0471	metal ion transport
Mag101_02405	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Mag101_02410	COG0509	glycine decarboxylation via glycine cleavage system
Mag101_02420	COG0494	nUDIX hydrolase
Mag101_02435	COG3108	Peptidase M15
Mag101_02445	COG2989	Protein conserved in bacteria
Mag101_02460	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Mag101_02465	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Mag101_02480	COG0811	peptide transport
Mag101_02490	COG0848	biopolymer transport protein
Mag101_02495	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Mag101_02505	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Mag101_02520	COG0129	dihydroxy-acid dehydratase activity
Mag101_02525	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Mag101_02525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Mag101_02540	COG0306	phosphate transporter
Mag101_02545	COG1392	Phosphate transport regulator
Mag101_02550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Mag101_02555	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Mag101_02590	COG0438	transferase activity, transferring glycosyl groups
Mag101_02605	COG1519	Transferase
Mag101_02615	COG0463	Glycosyl transferase, family 2
Mag101_02640	COG1538	Outer membrane efflux protein
Mag101_02645	COG2995	paraquat-inducible protein a
Mag101_02650	COG2995	paraquat-inducible protein a
Mag101_02655	COG3008	intermembrane lipid transfer
Mag101_02670	COG0494	nUDIX hydrolase
Mag101_02675	COG3151	Protein conserved in bacteria
Mag101_02680	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Mag101_02690	COG3150	esterase
Mag101_02705	COG2197	response regulator
Mag101_02710	COG4585	Histidine kinase
Mag101_02745	COG0385	Bile acid
Mag101_02750	COG0456	acetyltransferase
Mag101_02755	COG0513	Belongs to the DEAD box helicase family
Mag101_02760	COG1473	amidohydrolase
Mag101_02765	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Mag101_02775	COG3047	cAMP biosynthetic process
Mag101_02790	COG0829	nickel cation binding
Mag101_02795	COG0831	urea catabolic process
Mag101_02800	COG0832	Belongs to the urease beta subunit family
Mag101_02805	COG0804	urea catabolic process
Mag101_02810	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Mag101_02815	COG0830	nickel cation binding
Mag101_02820	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Mag101_02830	COG0745	RESPONSE REGULATOR receiver
Mag101_02835	COG2198	Histidine kinase
Mag101_02835	COG0784	Response regulator, receiver
Mag101_02835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Mag101_02835	COG2205	protein histidine kinase activity
Mag101_02850	COG0559	Belongs to the binding-protein-dependent transport system permease family
Mag101_02865	COG0410	ABC transporter
Mag101_02905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Mag101_02905	COG2205	protein histidine kinase activity
Mag101_02915	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Mag101_02925	COG0488	(ABC) transporter
Mag101_02930	COG1024	Enoyl-CoA hydratase
Mag101_02935	COG1523	belongs to the glycosyl hydrolase 13 family
Mag101_02950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mag101_02970	COG3721	Heme iron utilization protein
Mag101_02985	COG0811	peptide transport
Mag101_02990	COG0848	biopolymer transport protein
Mag101_03000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Mag101_03005	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Mag101_03010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Mag101_03015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Mag101_03020	COG0735	belongs to the Fur family
Mag101_03025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Mag101_03030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Mag101_03030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Mag101_03045	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Mag101_03050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Mag101_03060	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Mag101_03070	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Mag101_03075	COG1162	GTPase activity
Mag101_03085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Mag101_03090	COG2111	Na H antiporter
Mag101_03090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Mag101_03100	COG0651	ATP synthesis coupled electron transport
Mag101_03105	COG0651	ATP synthesis coupled electron transport
Mag101_03110	COG1006	Multisubunit Na H antiporter MnhC subunit
Mag101_03125	COG2212	antiporter activity
Mag101_03140	COG0142	geranyltranstransferase activity
Mag101_03150	COG4206	TonB-dependent receptor
Mag101_03160	COG4191	Histidine kinase
Mag101_03195	COG1181	Belongs to the D-alanine--D-alanine ligase family
Mag101_03205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Mag101_03215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Mag101_03225	COG2815	serine threonine protein kinase
Mag101_03225	COG0515	serine threonine protein kinase
Mag101_03230	COG2815	serine threonine protein kinase
Mag101_03230	COG0515	serine threonine protein kinase
Mag101_03250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Mag101_03255	COG1917	Cupin 2, conserved barrel domain protein
Mag101_03260	COG0527	aspartate kinase activity
Mag101_03265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Mag101_03285	COG0598	Magnesium transport protein CorA
Mag101_03300	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Mag101_03350	COG1294	oxidase, subunit
Mag101_03355	COG1271	oxidase subunit
Mag101_03385	COG0523	cobalamin synthesis protein
Mag101_03395	COG3119	arylsulfatase activity
Mag101_03415	COG1228	amidohydrolase
Mag101_03440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Mag101_03470	COG2015	COG2015, Alkyl sulfatase and related hydrolases
Mag101_03495	COG2130	NADP-dependent
Mag101_03505	COG1649	PFAM Uncharacterised BCR, COG1649
Mag101_03520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Mag101_03525	COG0733	neurotransmitter:sodium symporter activity
Mag101_03530	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Mag101_03535	COG0733	neurotransmitter:sodium symporter activity
Mag101_03540	COG2867	negative regulation of translational initiation
Mag101_03565	COG0497	DNA recombination
Mag101_03570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Mag101_03575	COG0443	Heat shock 70 kDa protein
Mag101_03580	COG0484	heat shock protein binding
Mag101_03590	COG3507	Belongs to the glycosyl hydrolase 43 family
Mag101_03595	COG2211	Major facilitator Superfamily
Mag101_03615	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Mag101_03620	COG4067	protein conserved in archaea
Mag101_03620	COG0189	ligase activity
Mag101_03630	COG0505	Belongs to the CarA family
Mag101_03640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Mag101_03665	COG1462	curli production assembly transport component CsgG
Mag101_03680	COG2197	response regulator
Mag101_03685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Mag101_03690	COG1131	(ABC) transporter
Mag101_03695	COG0842	Transport permease protein
Mag101_03705	COG0584	glycerophosphoryl diester phosphodiesterase
Mag101_03710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Mag101_03730	COG0842	Transport permease protein
Mag101_03735	COG1131	(ABC) transporter
Mag101_03740	COG0412	Dienelactone hydrolase
Mag101_03745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Mag101_03750	COG0303	'Molybdopterin
Mag101_03755	COG0243	molybdopterin cofactor binding
Mag101_03760	COG2146	nitrite reductase [NAD(P)H] activity
Mag101_03765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Mag101_03765	COG2146	nitrite reductase [NAD(P)H] activity
Mag101_03775	COG2223	nitrite transmembrane transporter activity
Mag101_03780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Mag101_03780	COG1116	anion transmembrane transporter activity
Mag101_03785	COG3707	response regulator
Mag101_03795	COG0746	molybdenum cofactor guanylyltransferase activity
Mag101_03810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Mag101_03830	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Mag101_03835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Mag101_03840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Mag101_03845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Mag101_03850	COG0149	triose-phosphate isomerase activity
Mag101_03855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Mag101_03865	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Mag101_03880	COG0217	transcriptional regulatory protein
Mag101_03885	COG2252	PERMEase
Mag101_03895	COG0469	pyruvate kinase activity
Mag101_03900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Mag101_03905	COG0521	Mo-molybdopterin cofactor biosynthetic process
Mag101_03910	COG0315	cyclic pyranopterin monophosphate synthase activity
Mag101_03915	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Mag101_03950	COG0811	peptide transport
Mag101_03995	COG0779	Required for maturation of 30S ribosomal subunits
Mag101_04000	COG0195	Participates in both transcription termination and antitermination
Mag101_04005	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Mag101_04010	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Mag101_04015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Mag101_04020	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Mag101_04025	COG1185	polyribonucleotide nucleotidyltransferase activity
Mag101_04030	COG0730	response to heat
Mag101_04035	COG3104	oligopeptide transport
Mag101_04050	COG2095	MarC family integral membrane protein
Mag101_04060	COG4206	TonB-dependent receptor
Mag101_04065	COG4771	TonB-dependent receptor
Mag101_04070	COG4206	TonB-dependent receptor
Mag101_04085	COG1595	DNA-templated transcription, initiation
Mag101_04090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Mag101_04095	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Mag101_04100	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Mag101_04110	COG3100	YcgL domain-containing protein
Mag101_04115	COG2983	Belongs to the UPF0260 family
Mag101_04130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Mag101_04140	COG3104	oligopeptide transport
Mag101_04145	COG1643	Atp-dependent helicase
Mag101_04155	COG3220	belongs to the UPF0276 family
Mag101_04165	COG2853	Lipoprotein
Mag101_04185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Mag101_04190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Mag101_04225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Mag101_04230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Mag101_04285	COG1215	transferase activity, transferring glycosyl groups
Mag101_04310	COG0438	transferase activity, transferring glycosyl groups
Mag101_04310	COG1216	Glycosyl transferase, family 2
Mag101_04335	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Mag101_04335	COG0662	Cupin 2, conserved barrel domain protein
Mag101_04340	COG4464	protein tyrosine phosphatase activity
Mag101_04355	COG0583	DNA-binding transcription factor activity
Mag101_04360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Mag101_04365	COG0006	proline dipeptidase activity
Mag101_04370	COG0788	formyltetrahydrofolate deformylase activity
Mag101_04380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Mag101_04380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Mag101_04395	COG0018	arginyl-trna synthetase
Mag101_04400	COG2925	Exonuclease
Mag101_04405	COG0540	Belongs to the ATCase OTCase family
Mag101_04410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Mag101_04420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Mag101_04425	COG2971	BadF BadG BcrA BcrD
Mag101_04430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Mag101_04435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Mag101_04440	COG0738	Major facilitator superfamily
Mag101_04450	COG1609	Transcriptional regulator
Mag101_04455	COG0166	Belongs to the GPI family
Mag101_04460	COG0129	dihydroxy-acid dehydratase activity
Mag101_04465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Mag101_04470	COG0363	glucosamine-6-phosphate deaminase activity
Mag101_04475	COG0800	Aldolase
Mag101_04485	COG0469	pyruvate kinase activity
Mag101_04540	COG0193	aminoacyl-tRNA hydrolase activity
Mag101_04545	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Mag101_04550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Mag101_04565	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
Mag101_04580	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Mag101_04600	COG0534	Mate efflux family protein
Mag101_04625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Mag101_04630	COG0154	amidase activity
Mag101_04635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Mag101_04640	COG1077	Cell shape determining protein MreB Mrl
Mag101_04645	COG1792	Involved in formation and maintenance of cell shape
Mag101_04655	COG0424	maF-like protein
Mag101_04660	COG1530	ribonuclease E activity
Mag101_04675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Mag101_04680	COG2321	neutral zinc metallopeptidase
Mag101_04695	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Mag101_04700	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Mag101_04705	COG0799	negative regulation of ribosome biogenesis
Mag101_04710	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Mag101_04715	COG0768	penicillin binding
Mag101_04720	COG0772	Belongs to the SEDS family
Mag101_04725	COG2951	lytic endotransglycosylase activity
Mag101_04735	COG1686	Belongs to the peptidase S11 family
Mag101_04740	COG2921	Belongs to the UPF0250 family
Mag101_04745	COG0321	lipoyl(octanoyl) transferase activity
Mag101_04750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Mag101_04795	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Mag101_04805	COG3240	lipase activity
Mag101_04805	COG4625	pathogenesis
Mag101_04810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Mag101_04830	COG0587	DNA-directed DNA polymerase activity
Mag101_04845	COG0717	Belongs to the dCTP deaminase family
Mag101_04850	COG2081	HI0933 family
Mag101_04930	COG2223	nitrite transmembrane transporter activity
Mag101_04945	COG2181	nitrate reductase activity
Mag101_04950	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Mag101_04955	COG1140	nitrate reductase beta subunit
Mag101_04960	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Mag101_04970	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Mag101_04975	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Mag101_04985	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Mag101_04990	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Mag101_04990	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Mag101_05000	COG3279	Response regulator of the LytR AlgR family
Mag101_05005	COG2972	Histidine kinase
Mag101_05060	COG3530	Putative quorum-sensing-regulated virulence factor
Mag101_05085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Mag101_05100	COG2009	succinate dehydrogenase
Mag101_05105	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Mag101_05110	COG1053	succinate dehydrogenase
Mag101_05115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Mag101_05135	COG0045	succinate-CoA ligase (ADP-forming) activity
Mag101_05150	COG1278	Cold shock
Mag101_05165	COG0456	acetyltransferase
Mag101_05170	COG2824	Alkylphosphonate utilization operon protein PhnA
Mag101_05180	COG3034	peptidoglycan biosynthetic process
Mag101_05190	COG1794	racemase activity, acting on amino acids and derivatives
Mag101_05235	COG2154	pterin-4-alpha-carbinolamine dehydratase
Mag101_05240	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Mag101_05245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Mag101_05265	COG0277	FAD linked oxidase domain protein
Mag101_05280	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Mag101_05315	COG3119	arylsulfatase activity
Mag101_05320	COG3119	arylsulfatase activity
Mag101_05355	COG0714	Associated with various cellular activities
Mag101_05370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Mag101_05385	COG1307	EDD domain protein, DegV family
Mag101_05395	COG1472	Belongs to the glycosyl hydrolase 3 family
Mag101_05400	COG0477	Major facilitator Superfamily
Mag101_05415	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Mag101_05430	COG0504	CTP synthase activity
Mag101_05440	COG0148	phosphopyruvate hydratase activity
Mag101_05445	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Mag101_05450	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Mag101_05455	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Mag101_05460	COG0585	pseudouridine synthase activity
Mag101_05465	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Mag101_05500	COG0405	Gamma-glutamyltransferase
Mag101_05505	COG0308	aminopeptidase N
Mag101_05515	COG2272	Belongs to the type-B carboxylesterase lipase family
Mag101_05525	COG2211	Major facilitator Superfamily
Mag101_05545	COG1132	(ABC) transporter
Mag101_05560	COG0189	ligase activity
Mag101_05560	COG1181	Belongs to the D-alanine--D-alanine ligase family
Mag101_05560	COG2918	glutathione biosynthetic process
Mag101_05570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Mag101_05575	COG0446	pyridine nucleotide-disulphide oxidoreductase
Mag101_05575	COG1902	pentaerythritol trinitrate reductase activity
Mag101_05580	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_05585	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_05605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Mag101_05615	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Mag101_05620	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Mag101_05665	COG1522	sequence-specific DNA binding
Mag101_05690	COG3119	arylsulfatase activity
Mag101_05710	COG4948	Mandelate Racemase Muconate Lactonizing
Mag101_05720	COG2814	Major facilitator Superfamily
Mag101_05725	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_05735	COG4948	Mandelate Racemase Muconate Lactonizing
Mag101_05740	COG3734	2-keto-3-deoxy-galactonokinase
Mag101_05745	COG0800	Aldolase
Mag101_05780	COG2186	Transcriptional regulator
Mag101_05785	COG2186	Transcriptional regulator
Mag101_05805	COG3119	arylsulfatase activity
Mag101_05810	COG3119	arylsulfatase activity
Mag101_05835	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Mag101_05860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Mag101_05885	COG1012	belongs to the aldehyde dehydrogenase family
Mag101_05895	COG0148	phosphopyruvate hydratase activity
Mag101_05900	COG0431	NADPH-dependent FMN reductase
Mag101_05930	COG2271	Major facilitator Superfamily
Mag101_05940	COG3386	PFAM SMP-30 Gluconolaconase
Mag101_05945	COG3250	beta-galactosidase activity
Mag101_05955	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Mag101_05970	COG1012	belongs to the aldehyde dehydrogenase family
Mag101_05975	COG1024	Enoyl-CoA hydratase
Mag101_05980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Mag101_05985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Mag101_06000	COG0800	Aldolase
Mag101_06005	COG2814	Major facilitator Superfamily
Mag101_06010	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_06015	COG4948	Mandelate Racemase Muconate Lactonizing
Mag101_06030	COG4948	Mandelate Racemase Muconate Lactonizing
Mag101_06035	COG1063	alcohol dehydrogenase
Mag101_06040	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_06045	COG1012	belongs to the aldehyde dehydrogenase family
Mag101_06055	COG3734	2-keto-3-deoxy-galactonokinase
Mag101_06075	COG0583	DNA-binding transcription factor activity
Mag101_06090	COG0154	amidase activity
Mag101_06095	COG4336	lyase activity
Mag101_06105	COG1984	allophanate hydrolase subunit 2
Mag101_06120	COG3023	N-Acetylmuramoyl-L-alanine amidase
Mag101_06165	COG4948	Mandelate Racemase Muconate Lactonizing
Mag101_06185	COG1619	proteins homologs of microcin C7 resistance protein MccF
Mag101_06190	COG1757	Na H antiporter
Mag101_06200	COG3876	Protein conserved in bacteria
Mag101_06210	COG0277	FAD linked oxidase domain protein
Mag101_06215	COG0277	FAD linked oxidase domain protein
Mag101_06220	COG0247	lactate metabolic process
Mag101_06245	COG1611	Belongs to the LOG family
Mag101_06270	COG5016	pyruvate
Mag101_06270	COG0511	ligase activity, forming carbon-carbon bonds
Mag101_06275	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Mag101_06280	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Mag101_06285	COG0271	Belongs to the BolA IbaG family
Mag101_06300	COG0789	Transcriptional regulator
Mag101_06320	COG0514	ATP-dependent DNA helicase (RecQ)
Mag101_06340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Mag101_06340	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Mag101_06345	COG0716	FMN binding
Mag101_06350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Mag101_06365	COG3089	Belongs to the UPF0270 family
Mag101_06380	COG0425	Belongs to the sulfur carrier protein TusA family
Mag101_06390	COG3101	peptidyl-lysine hydroxylation
Mag101_06395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Mag101_06395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Mag101_06400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Mag101_06420	COG0436	Aminotransferase
Mag101_06425	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Mag101_06455	COG1131	(ABC) transporter
Mag101_06460	COG0842	Transport permease protein
Mag101_06465	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Mag101_06465	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Mag101_06490	COG2133	pyrroloquinoline quinone binding
Mag101_06495	COG1228	amidohydrolase
Mag101_06500	COG3119	arylsulfatase activity
Mag101_06510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Mag101_06540	COG4133	protoheme IX ABC transporter activity
Mag101_06545	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Mag101_06560	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Mag101_06575	COG1739	Uncharacterized protein family UPF0029
Mag101_06590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Mag101_06595	COG1538	Outer membrane efflux protein
Mag101_06700	COG3115	cell septum assembly
Mag101_06705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Mag101_06735	COG1960	acyl-CoA dehydrogenase activity
Mag101_06745	COG0318	PFAM AMP-dependent synthetase and ligase
Mag101_06755	COG2866	Carboxypeptidase
Mag101_06780	COG2072	flavoprotein involved in K transport
Mag101_06790	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_06800	COG0084	hydrolase, TatD family'
Mag101_06810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Mag101_06815	COG1047	Peptidyl-prolyl cis-trans
Mag101_06835	COG3106	COG3106 Predicted ATPase
Mag101_06840	COG3768	UPF0283 membrane protein
Mag101_06870	COG0071	Belongs to the small heat shock protein (HSP20) family
Mag101_06880	COG1917	Cupin 2, conserved barrel domain protein
Mag101_06880	COG4977	sequence-specific DNA binding
Mag101_06890	COG1250	3-hydroxyacyl-CoA dehydrogenase
Mag101_06890	COG1024	Enoyl-CoA hydratase
Mag101_06895	COG0183	Belongs to the thiolase family
Mag101_06905	COG0544	peptidyl-prolyl cis-trans isomerase activity
Mag101_06910	COG0740	serine-type endopeptidase activity
Mag101_06915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Mag101_06920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Mag101_06940	COG1388	LysM domain
Mag101_06940	COG0741	lytic transglycosylase activity
Mag101_06950	COG2226	methyltransferase
Mag101_06955	COG0328	RNA-DNA hybrid ribonuclease activity
Mag101_06960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Mag101_06965	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Mag101_06975	COG2816	NAD+ diphosphatase activity
Mag101_06985	COG0616	signal peptide processing
Mag101_06990	COG0604	alcohol dehydrogenase
Mag101_07005	COG0210	DNA helicase
Mag101_07020	COG2391	methyltransferase activity
Mag101_07025	COG0640	Transcriptional regulator
Mag101_07050	COG3122	Protein conserved in bacteria
Mag101_07060	COG3634	alkyl hydroperoxide reductase activity
Mag101_07065	COG0450	alkyl hydroperoxide reductase
Mag101_07075	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Mag101_07180	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Mag101_07185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Mag101_07190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Mag101_07195	COG0215	cysteine-tRNA ligase activity
Mag101_07225	COG1956	GAF domain-containing protein
Mag101_07240	COG2813	Specifically methylates the guanine in position
Mag101_07245	COG1187	pseudouridine synthase activity
Mag101_07250	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Mag101_07380	COG1802	Transcriptional regulator
Mag101_07380	COG4626	Terminase
Mag101_07385	COG4695	Portal protein
Mag101_07485	COG0529	Catalyzes the synthesis of activated sulfate
Mag101_07520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Mag101_07525	COG3206	protein involved in exopolysaccharide biosynthesis
Mag101_07525	COG0489	protein tyrosine kinase activity
Mag101_07530	COG1086	Polysaccharide biosynthesis protein
Mag101_07540	COG1083	cytidylyl-transferase
Mag101_07555	COG2089	acid synthase
Mag101_07570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Mag101_07585	COG1215	transferase activity, transferring glycosyl groups
Mag101_07590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Mag101_07600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Mag101_07615	COG2304	oxidoreductase activity
Mag101_07635	COG0714	Associated with various cellular activities
Mag101_07645	COG0167	dihydroorotate dehydrogenase activity
Mag101_07650	COG3130	regulation of translation
Mag101_07655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Mag101_07655	COG0116	Belongs to the methyltransferase superfamily
Mag101_07665	COG0631	protein serine/threonine phosphatase activity
Mag101_07680	COG0741	lytic transglycosylase activity
Mag101_07690	COG0589	response to stress
Mag101_07715	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Mag101_07730	COG1472	Belongs to the glycosyl hydrolase 3 family
Mag101_07735	COG0668	transmembrane transport
Mag101_07740	COG1278	Cold shock
Mag101_07755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Mag101_07765	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Mag101_07770	COG1805	sodium ion transport
Mag101_07785	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Mag101_07790	COG2871	sodium ion transport
Mag101_07795	COG1477	protein flavinylation
Mag101_07805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Mag101_07810	COG2050	protein possibly involved in aromatic compounds catabolism
Mag101_07825	COG4591	ABC-type transport system involved in lipoprotein release permease component
Mag101_07830	COG1136	(ABC) transporter
Mag101_07835	COG4591	ABC-type transport system involved in lipoprotein release permease component
Mag101_07850	COG1802	Transcriptional regulator
Mag101_07855	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Mag101_07860	COG0372	Belongs to the citrate synthase family
Mag101_07865	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Mag101_07890	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Mag101_07950	COG0417	DNA replication proofreading
Mag101_08005	COG0513	Belongs to the DEAD box helicase family
Mag101_08010	COG1404	Belongs to the peptidase S8 family
Mag101_08025	COG1944	ATP diphosphatase activity
Mag101_08040	COG0612	Peptidase, M16
Mag101_08055	COG0811	peptide transport
Mag101_08060	COG0848	biopolymer transport protein
Mag101_08065	COG1132	(ABC) transporter
Mag101_08070	COG1663	tetraacyldisaccharide 4'-kinase activity
Mag101_08075	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Mag101_08080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Mag101_08090	COG0322	excinuclease ABC activity
Mag101_08140	COG1946	Acyl-CoA thioesterase
Mag101_08160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Mag101_08285	COG0463	Glycosyl transferase, family 2
Mag101_08290	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Mag101_08295	COG0745	RESPONSE REGULATOR receiver
Mag101_08315	COG0431	NADPH-dependent FMN reductase
Mag101_08320	COG0798	PFAM Bile acid sodium symporter
Mag101_08330	COG0640	Transcriptional regulator
Mag101_08335	COG0708	Exodeoxyribonuclease III
Mag101_08340	COG0793	Belongs to the peptidase S41A family
Mag101_08345	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Mag101_08360	COG1595	DNA-templated transcription, initiation
Mag101_08385	COG3541	Predicted nucleotidyltransferase
Mag101_08460	COG0457	Tetratricopeptide repeat
Mag101_08490	COG0785	Cytochrome C biogenesis protein
Mag101_08500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Mag101_08535	COG0429	hydrolase of the alpha beta-hydrolase fold
Mag101_08545	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Mag101_08550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Mag101_08555	COG4771	TonB-dependent receptor
Mag101_08570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Mag101_08570	COG1648	precorrin-2 dehydrogenase activity
Mag101_08575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Mag101_08580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Mag101_08585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Mag101_08590	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Mag101_08595	COG1674	ftsk spoiiie
Mag101_08600	COG0492	ferredoxin-NADP+ reductase activity
Mag101_08605	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Mag101_08610	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Mag101_08615	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Mag101_08620	COG0542	response to heat
Mag101_08625	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Mag101_08630	COG1278	Cold shock
Mag101_08650	COG2915	High frequency lysogenization protein hflD homolog
Mag101_08660	COG2850	peptidyl-arginine hydroxylation
Mag101_08665	COG2153	protein acetylation
Mag101_08680	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Mag101_08705	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Mag101_08710	COG0857	belongs to the CobB CobQ family
Mag101_08710	COG0280	phosphate acetyltransferase
Mag101_08715	COG0427	acetyl-CoA hydrolase
Mag101_08730	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Mag101_08745	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Mag101_08750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Mag101_08775	COG4771	TonB-dependent receptor
Mag101_08780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Mag101_08790	COG1115	amino acid carrier protein
Mag101_08795	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Mag101_08800	COG1862	Preprotein translocase
Mag101_08810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Mag101_08820	COG0017	Asparaginyl-tRNA synthetase
Mag101_08825	COG0039	L-malate dehydrogenase activity
Mag101_08835	COG0084	hydrolase, TatD family'
Mag101_08850	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Mag101_08855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Mag101_08865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Mag101_08870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Mag101_08880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Mag101_08885	COG0416	fatty acid biosynthetic process
Mag101_08890	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Mag101_08895	COG1399	metal-binding, possibly nucleic acid-binding protein
Mag101_08900	COG0424	maF-like protein
Mag101_08905	COG0546	phosphoglycolate phosphatase activity
Mag101_08915	COG1530	ribonuclease E activity
Mag101_08950	COG0583	DNA-binding transcription factor activity
Mag101_08990	COG0398	Pfam SNARE associated Golgi protein
Mag101_09010	COG0670	Belongs to the BI1 family
Mag101_09030	COG2920	part of a sulfur-relay system
Mag101_09040	COG0583	DNA-binding transcription factor activity
Mag101_09045	COG0189	ligase activity
Mag101_09060	COG4067	protein conserved in archaea
Mag101_09060	COG0189	ligase activity
Mag101_09065	COG0432	Pfam Uncharacterised protein family UPF0047
Mag101_09070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Mag101_09085	COG1322	Protein conserved in bacteria
Mag101_09105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Mag101_09115	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Mag101_09120	COG0500	methyltransferase
Mag101_09125	COG1643	Atp-dependent helicase
Mag101_09130	COG0316	Belongs to the HesB IscA family
Mag101_09130	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Mag101_09150	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Mag101_09160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Mag101_09180	COG1522	sequence-specific DNA binding
Mag101_09190	COG4651	solute:proton antiporter activity
Mag101_09190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Mag101_09205	COG1538	Outer membrane efflux protein
Mag101_09210	COG1960	acyl-CoA dehydrogenase activity
Mag101_09230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Mag101_09250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Mag101_09265	COG4106	trans-aconitate 2-methyltransferase activity
Mag101_09270	COG0500	methyltransferase
Mag101_09275	COG1760	l-serine dehydratase
Mag101_09280	COG0742	ribosomal rna small subunit methyltransferase
Mag101_09305	COG2900	Belongs to the SlyX family
Mag101_09315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mag101_09320	COG0023	Translation Initiation Factor
Mag101_09330	COG1115	amino acid carrier protein
Mag101_09360	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Mag101_09360	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Mag101_09360	COG0506	proline dehydrogenase activity
Mag101_09390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Mag101_09405	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_09415	COG1595	DNA-templated transcription, initiation
Mag101_09430	COG1522	sequence-specific DNA binding
Mag101_09435	COG0339	signal peptide processing
Mag101_09445	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Mag101_09450	COG1448	Aminotransferase
Mag101_09460	COG0625	glutathione transferase activity
Mag101_09495	COG3788	relative of glutathione S-transferase, MAPEG superfamily
Mag101_09505	COG1228	amidohydrolase
Mag101_09520	COG3012	SEC-C Motif Domain Protein
Mag101_09540	COG1446	asparaginase
Mag101_09570	COG4771	TonB-dependent receptor
Mag101_09600	COG0339	signal peptide processing
Mag101_09610	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Mag101_09610	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Mag101_09615	COG0509	glycine decarboxylation via glycine cleavage system
Mag101_09625	COG1760	l-serine dehydratase
Mag101_09630	COG0583	DNA-binding transcription factor activity
Mag101_09655	COG2153	protein acetylation
Mag101_09680	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Mag101_09690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Mag101_09695	COG4771	TonB-dependent receptor
Mag101_09700	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Mag101_09705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Mag101_09710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Mag101_09720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Mag101_09725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Mag101_09735	COG2030	dehydratase
Mag101_09770	COG1335	isochorismatase
Mag101_09785	COG2188	Transcriptional regulator
Mag101_09795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Mag101_09815	COG1012	belongs to the aldehyde dehydrogenase family
Mag101_09830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Mag101_09855	COG1335	isochorismatase
Mag101_09865	COG1012	belongs to the aldehyde dehydrogenase family
Mag101_09870	COG1960	acyl-CoA dehydrogenase activity
Mag101_09885	COG2814	Major facilitator Superfamily
Mag101_09890	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_09910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Mag101_09915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Mag101_09920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Mag101_09925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mag101_09940	COG1024	Enoyl-CoA hydratase
Mag101_09945	COG0154	amidase activity
Mag101_09970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Mag101_10015	COG0776	regulation of translation
Mag101_10025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Mag101_10030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Mag101_10035	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Mag101_10040	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Mag101_10045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Mag101_10065	COG0612	Peptidase, M16
Mag101_10070	COG1136	(ABC) transporter
Mag101_10070	COG0577	efflux transmembrane transporter activity
Mag101_10090	COG1136	(ABC) transporter
Mag101_10100	COG0556	nucleotide-excision repair
Mag101_10115	COG1555	photosystem II stabilization
Mag101_10125	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Mag101_10135	COG0776	regulation of translation
Mag101_10145	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Mag101_10150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Mag101_10155	COG0077	Prephenate dehydratase
Mag101_10155	COG1605	Chorismate mutase
Mag101_10160	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Mag101_10170	COG0402	S-adenosylhomocysteine deaminase activity
Mag101_10185	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_10225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Mag101_10230	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Mag101_10245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Mag101_10255	COG0438	transferase activity, transferring glycosyl groups
Mag101_10280	COG1522	sequence-specific DNA binding
Mag101_10285	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Mag101_10290	COG0110	maltose O-acetyltransferase activity
Mag101_10310	COG0438	transferase activity, transferring glycosyl groups
Mag101_10320	COG0174	glutamine synthetase
Mag101_10340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Mag101_10345	COG1288	antiporter activity
Mag101_10350	COG4206	TonB-dependent receptor
Mag101_10375	COG0346	lactoylglutathione lyase activity
Mag101_10385	COG2968	Membrane
Mag101_10405	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
Mag101_10410	COG2195	Cleaves the N-terminal amino acid of tripeptides
Mag101_10420	COG2974	May be involved in recombination
Mag101_10430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Mag101_10465	COG0745	RESPONSE REGULATOR receiver
Mag101_10480	COG2084	Dehydrogenase
Mag101_10485	COG1968	undecaprenyl-diphosphatase activity
Mag101_10490	COG1214	PFAM Peptidase M22, glycoprotease
Mag101_10500	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Mag101_10505	COG0563	adenylate kinase activity
Mag101_10510	COG3956	TIGRFAM MazG family protein
Mag101_10515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Mag101_10525	COG5002	protein histidine kinase activity
Mag101_10525	COG2205	protein histidine kinase activity
Mag101_10525	COG0784	Response regulator, receiver
Mag101_10535	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Mag101_10540	COG0571	ribonuclease III activity
Mag101_10555	COG0481	GTPase activity
Mag101_10560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Mag101_10565	COG2866	Carboxypeptidase
Mag101_10570	COG4948	Mandelate Racemase Muconate Lactonizing
Mag101_10575	COG3086	response to oxidative stress
Mag101_10605	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Mag101_10610	COG0354	folic acid binding
Mag101_10620	COG1573	uracil-dna glycosylase
Mag101_10630	COG1666	GTP binding
Mag101_10635	COG4681	YaeQ
Mag101_10645	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Mag101_10655	COG0750	zinc metalloprotease
Mag101_10660	COG1234	tRNA 3'-trailer cleavage
Mag101_10685	COG1234	tRNA 3'-trailer cleavage
Mag101_10690	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Mag101_10700	COG0789	Transcriptional regulator
Mag101_10710	COG1280	lysine exporter protein (LysE YggA)
Mag101_10720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Mag101_10735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Mag101_10740	COG0335	large ribosomal subunit rRNA binding
Mag101_10745	COG0336	Belongs to the RNA methyltransferase TrmD family
Mag101_10750	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Mag101_10755	COG0228	four-way junction DNA binding
Mag101_10760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Mag101_10765	COG4137	Cytochrome C assembly protein
Mag101_10770	COG4536	flavin adenine dinucleotide binding
Mag101_10775	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Mag101_10780	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Mag101_10785	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Mag101_10790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Mag101_10795	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Mag101_10805	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Mag101_10815	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Mag101_10820	COG0575	Belongs to the CDS family
Mag101_10825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Mag101_10830	COG0233	cytoplasmic translational termination
Mag101_10835	COG0528	UMP kinase activity
Mag101_10840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Mag101_10845	COG0052	Belongs to the universal ribosomal protein uS2 family
Mag101_10850	COG0024	Methionine aminopeptidase
Mag101_10855	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Mag101_10860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Mag101_10865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Mag101_10870	COG1393	Belongs to the ArsC family
Mag101_10875	COG2171	N-acyltransferase activity
Mag101_10880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Mag101_10900	COG0745	RESPONSE REGULATOR receiver
Mag101_10905	COG2205	protein histidine kinase activity
Mag101_10920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Mag101_10930	COG0009	L-threonylcarbamoyladenylate synthase
Mag101_10935	COG0613	PHP domain protein
Mag101_10945	COG2350	Protein conserved in bacteria
Mag101_10960	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Mag101_10970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Mag101_10980	COG2885	chlorophyll binding
Mag101_10985	COG3842	ATPase activity
Mag101_10990	COG1178	ABC-type Fe3 transport system permease component
Mag101_11005	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Mag101_11015	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Mag101_11015	COG0519	Catalyzes the synthesis of GMP from XMP
Mag101_11025	COG1570	exodeoxyribonuclease VII activity
Mag101_11030	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Mag101_11045	COG0259	pyridoxamine-phosphate oxidase activity
Mag101_11085	COG1960	acyl-CoA dehydrogenase activity
Mag101_11090	COG1024	Enoyl-CoA hydratase
Mag101_11105	COG1960	acyl-CoA dehydrogenase activity
Mag101_11115	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_11120	COG1063	alcohol dehydrogenase
Mag101_11125	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Mag101_11140	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
Mag101_11140	COG0778	Nitroreductase
Mag101_11155	COG4771	TonB-dependent receptor
Mag101_11160	COG4771	TonB-dependent receptor
Mag101_11170	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Mag101_11190	COG2124	cytochrome p450
Mag101_11200	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_11205	COG0318	PFAM AMP-dependent synthetase and ligase
Mag101_11220	COG0183	Belongs to the thiolase family
Mag101_11230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Mag101_11235	COG0508	dehydrogenase complex catalyzes the overall conversion of
Mag101_11240	COG0022	dehydrogenase e1 component
Mag101_11245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Mag101_11250	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Mag101_11260	COG2130	NADP-dependent
Mag101_11285	COG1960	acyl-CoA dehydrogenase activity
Mag101_11290	COG1012	belongs to the aldehyde dehydrogenase family
Mag101_11295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Mag101_11325	COG1024	Enoyl-CoA hydratase
Mag101_11330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Mag101_11345	COG1250	3-hydroxyacyl-CoA dehydrogenase
Mag101_11345	COG1024	Enoyl-CoA hydratase
Mag101_11350	COG0183	Belongs to the thiolase family
Mag101_11365	COG0025	NhaP-type Na H and K H
Mag101_11370	COG0067	glutamate synthase
Mag101_11370	COG0070	glutamate synthase
Mag101_11370	COG0069	glutamate synthase activity
Mag101_11380	COG2827	Endonuclease containing a URI domain
Mag101_11385	COG2755	lipolytic protein G-D-S-L family
Mag101_11385	COG0657	acetylesterase activity
Mag101_11410	COG2226	methyltransferase
Mag101_11440	COG0671	phosphoesterase, PA-phosphatase related
Mag101_11460	COG0745	RESPONSE REGULATOR receiver
Mag101_11505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Mag101_11510	COG1295	ribonuclease BN
Mag101_11515	COG1393	Belongs to the ArsC family
Mag101_11530	COG0616	signal peptide processing
Mag101_11545	COG3769	mannosylglycerate metabolic process
Mag101_11550	COG1215	transferase activity, transferring glycosyl groups
Mag101_11555	COG0366	Alpha amylase catalytic
Mag101_11575	COG0714	Associated with various cellular activities
Mag101_11590	COG1286	toxin biosynthetic process
Mag101_11600	COG0285	dihydrofolate synthase activity
Mag101_11605	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Mag101_11610	COG0159	tryptophan synthase activity
Mag101_11615	COG0133	tryptophan synthase activity
Mag101_11620	COG0135	phosphoribosylanthranilate isomerase activity
Mag101_11645	COG0473	3-isopropylmalate dehydrogenase activity
Mag101_11650	COG0066	3-isopropylmalate dehydratase activity
Mag101_11655	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Mag101_11670	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Mag101_11675	COG2890	protein-(glutamine-N5) methyltransferase activity
Mag101_11680	COG0302	gtp cyclohydrolase
Mag101_11690	COG0596	Alpha beta hydrolase
Mag101_11710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Mag101_11720	COG0326	Molecular chaperone. Has ATPase activity
Mag101_11730	COG0450	alkyl hydroperoxide reductase
Mag101_11735	COG2906	2 iron, 2 sulfur cluster binding
Mag101_11755	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Mag101_11760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Mag101_11765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Mag101_11770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Mag101_11770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Mag101_11775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Mag101_11785	COG0791	NLP P60 protein
Mag101_11790	COG2738	Putative neutral zinc metallopeptidase
Mag101_11810	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Mag101_11820	COG0531	amino acid
Mag101_11825	COG0076	glutamate decarboxylase activity
Mag101_11845	COG4628	conserved protein (DUF2132)
Mag101_11945	COG0459	protein refolding
Mag101_11950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Mag101_11960	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_11970	COG3695	enzyme binding
Mag101_11975	COG2211	Major facilitator Superfamily
Mag101_11980	COG1881	PFAM PEBP family protein
Mag101_11990	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Mag101_11995	COG3023	N-Acetylmuramoyl-L-alanine amidase
Mag101_12055	COG2010	Cytochrome c
Mag101_12070	COG3278	Belongs to the heme-copper respiratory oxidase family
Mag101_12075	COG0137	argininosuccinate synthase activity
Mag101_12080	COG0418	dihydroorotase activity
Mag101_12105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Mag101_12115	COG0343	queuine tRNA-ribosyltransferase activity
Mag101_12120	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Mag101_12160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Mag101_12165	COG0527	aspartate kinase activity
Mag101_12170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Mag101_12175	COG0537	adenosine 5'-monophosphoramidase activity
Mag101_12180	COG2835	tetraacyldisaccharide 4'-kinase activity
Mag101_12185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Mag101_12190	COG1228	amidohydrolase
Mag101_12195	COG2137	regulation of response to DNA damage stimulus
Mag101_12200	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Mag101_12215	COG1505	serine-type exopeptidase activity
Mag101_12220	COG0471	metal ion transport
Mag101_12230	COG3228	Belongs to the MtfA family
Mag101_12235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Mag101_12260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Mag101_12280	COG0783	Belongs to the Dps family
Mag101_12300	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Mag101_12305	COG0686	Belongs to the AlaDH PNT family
Mag101_12320	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Mag101_12325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Mag101_12335	COG0037	tRNA processing
Mag101_12345	COG4181	ATPase activity
Mag101_12350	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Mag101_12355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Mag101_12365	COG4232	protein-disulfide reductase activity
Mag101_12370	COG0709	Synthesizes selenophosphate from selenide and ATP
Mag101_12375	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Mag101_12395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Mag101_12445	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Mag101_12445	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Mag101_12465	COG2010	Cytochrome c
Mag101_12475	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Mag101_12485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Mag101_12490	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Mag101_12500	COG2067	long-chain fatty acid transport protein
Mag101_12505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Mag101_12505	COG1116	anion transmembrane transporter activity
Mag101_12510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Mag101_12515	COG1116	anion transmembrane transporter activity
Mag101_12535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Mag101_12545	COG2022	thiamine diphosphate biosynthetic process
Mag101_12570	COG0825	malonyl-CoA metabolic process
Mag101_12590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Mag101_12630	COG5265	(ABC) transporter
Mag101_12645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Mag101_12675	COG3118	belongs to the thioredoxin family
Mag101_12680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Mag101_12695	COG0583	DNA-binding transcription factor activity
Mag101_12700	COG0431	NADPH-dependent FMN reductase
Mag101_12710	COG0590	tRNA wobble adenosine to inosine editing
Mag101_12715	COG2226	methyltransferase
Mag101_12740	COG0795	lipopolysaccharide-transporting ATPase activity
Mag101_12745	COG0795	lipopolysaccharide-transporting ATPase activity
Mag101_12750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Mag101_12765	COG0525	valine-tRNA ligase activity
Mag101_12780	COG4067	protein conserved in archaea
Mag101_12780	COG0189	ligase activity
Mag101_12790	COG1199	ATP-dependent helicase activity
Mag101_12815	COG0166	Belongs to the GPI family
Mag101_12820	COG0330	HflC and HflK could
Mag101_12855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Mag101_12860	COG1702	phosphate starvation-inducible protein PhoH
Mag101_12870	COG4535	Mg2 and Co2 transporter CorC
Mag101_12875	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Mag101_12880	COG1090	epimerase
Mag101_12900	COG0495	leucyl-tRNA aminoacylation
Mag101_12910	COG1466	dna polymerase III delta subunit
Mag101_12915	COG1960	acyl-CoA dehydrogenase activity
Mag101_12925	COG1404	Belongs to the peptidase S8 family
Mag101_12935	COG3275	phosphorelay sensor kinase activity
Mag101_12950	COG1982	Orn Lys Arg decarboxylase major
Mag101_12990	COG0288	reversible hydration of carbon dioxide
Mag101_12995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Mag101_13000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Mag101_13050	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Mag101_13065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Mag101_13080	COG1160	GTP binding
Mag101_13090	COG2976	Protein conserved in bacteria
Mag101_13095	COG0124	histidyl-tRNA synthetase
Mag101_13100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Mag101_13115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Mag101_13120	COG0105	UTP biosynthetic process
Mag101_13140	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Mag101_13150	COG0822	iron-sulfur transferase activity
Mag101_13175	COG5001	Diguanylate cyclase
Mag101_13175	COG3447	MASE1 domain protein
Mag101_13175	COG5002	protein histidine kinase activity
Mag101_13180	COG0784	Response regulator, receiver
Mag101_13180	COG2205	protein histidine kinase activity
Mag101_13180	COG5002	protein histidine kinase activity
Mag101_13215	COG0653	protein targeting
Mag101_13220	COG0739	heme binding
Mag101_13225	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Mag101_13245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Mag101_13250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Mag101_13255	COG0772	Belongs to the SEDS family
Mag101_13260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Mag101_13265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Mag101_13270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Mag101_13275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Mag101_13290	COG0275	rRNA processing
Mag101_13295	COG2001	Belongs to the MraZ family
Mag101_13300	COG0175	sulfate reduction
Mag101_13310	COG2072	flavoprotein involved in K transport
Mag101_13315	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_13340	COG0792	nuclease activity
Mag101_13345	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Mag101_13350	COG2823	Periplasmic or secreted lipoprotein
Mag101_13360	COG1704	LemA family
Mag101_13365	COG0501	Belongs to the peptidase M48B family
Mag101_13375	COG2969	positive regulation of protein catabolic process
Mag101_13380	COG0625	glutathione transferase activity
Mag101_13385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Mag101_13390	COG0723	plastoquinol--plastocyanin reductase activity
Mag101_13395	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Mag101_13400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Mag101_13405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Mag101_13415	COG2046	Belongs to the sulfate adenylyltransferase family
Mag101_13420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Mag101_13435	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Mag101_13440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Mag101_13445	COG0271	Belongs to the BolA IbaG family
Mag101_13460	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Mag101_13470	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Mag101_13475	COG1137	ATPase activity
Mag101_13495	COG1660	Displays ATPase and GTPase activities
Mag101_13505	COG2239	Acts as a magnesium transporter
Mag101_13535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Mag101_13540	COG0205	6-phosphofructokinase activity
Mag101_13545	COG0174	glutamine synthetase
Mag101_13550	COG2819	hydrolase of the alpha beta superfamily
Mag101_13575	COG0174	glutamine synthetase
Mag101_13580	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Mag101_13585	COG2818	Glycosylase
Mag101_13595	COG1045	serine acetyltransferase
Mag101_13610	COG0501	Belongs to the peptidase M48B family
Mag101_13625	COG1489	DNA binding
Mag101_13630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Mag101_13635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Mag101_13640	COG3852	Histidine kinase
Mag101_13660	COG1428	Deoxynucleoside kinase
Mag101_13665	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Mag101_13675	COG0598	Magnesium transport protein CorA
Mag101_13680	COG0676	glucose-6-phosphate 1-epimerase activity
Mag101_13685	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Mag101_13695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Mag101_13700	COG1560	Kdo2-lipid A biosynthetic process
Mag101_13710	COG4771	TonB-dependent receptor
Mag101_13715	COG0667	Aldo Keto reductase
Mag101_13720	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Mag101_13730	COG0589	response to stress
Mag101_13735	COG0659	secondary active sulfate transmembrane transporter activity
Mag101_13740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Mag101_13745	COG1136	(ABC) transporter
Mag101_13760	COG2204	response regulator
Mag101_13765	COG5002	protein histidine kinase activity
Mag101_13785	COG0508	dehydrogenase complex catalyzes the overall conversion of
Mag101_13820	COG0425	Belongs to the sulfur carrier protein TusA family
Mag101_13825	COG4783	chaperone-mediated protein folding
Mag101_13830	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Mag101_13845	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Mag101_13850	COG0602	queuosine metabolic process
Mag101_13860	COG2885	chlorophyll binding
Mag101_13865	COG0823	Involved in the tonB-independent uptake of proteins
Mag101_13885	COG0824	Thioesterase
Mag101_13890	COG2255	four-way junction helicase activity
Mag101_13895	COG0632	four-way junction helicase activity
Mag101_13900	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Mag101_13910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Mag101_13920	COG0776	regulation of translation
Mag101_13925	COG0442	prolyl-tRNA aminoacylation
Mag101_13945	COG4946	Tricorn protease homolog
Mag101_13945	COG0823	Involved in the tonB-independent uptake of proteins
Mag101_13945	COG1506	peptidase
Mag101_13960	COG1522	sequence-specific DNA binding
Mag101_13980	COG0415	Belongs to the DNA photolyase family
Mag101_13990	COG0277	FAD linked oxidase domain protein
Mag101_13990	COG0247	lactate metabolic process
Mag101_14030	COG0489	protein tyrosine kinase activity
Mag101_14035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Mag101_14035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Mag101_14045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Mag101_14060	COG3707	response regulator
Mag101_14070	COG0625	glutathione transferase activity
Mag101_14080	COG0454	-acetyltransferase
Mag101_14085	COG4657	Part of a membrane complex involved in electron transport
Mag101_14090	COG2878	Part of a membrane complex involved in electron transport
Mag101_14100	COG4658	electron transport chain
Mag101_14105	COG4659	FMN binding
Mag101_14110	COG4660	Part of a membrane complex involved in electron transport
Mag101_14120	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Mag101_14140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Mag101_14215	COG0584	glycerophosphoryl diester phosphodiesterase
Mag101_14220	COG3706	GGDEF domain
Mag101_14225	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Mag101_14230	COG3483	tryptophan 2,3-dioxygenase activity
Mag101_14235	COG0848	biopolymer transport protein
Mag101_14240	COG1803	Methylglyoxal synthase
Mag101_14260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Mag101_14280	COG3590	peptidase
Mag101_14285	COG0477	Major facilitator Superfamily
Mag101_14295	COG2234	aminopeptidase activity
Mag101_14295	COG4935	Belongs to the peptidase S8 family
Mag101_14310	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Mag101_14320	COG0534	Mate efflux family protein
Mag101_14335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Mag101_14340	COG0386	Belongs to the glutathione peroxidase family
Mag101_14370	COG1183	phosphatidylcholine synthase activity
Mag101_14375	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Mag101_14385	COG0028	Belongs to the TPP enzyme family
Mag101_14395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Mag101_14400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Mag101_14425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Mag101_14425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Mag101_14475	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Mag101_14480	COG1047	Peptidyl-prolyl cis-trans
Mag101_14490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Mag101_14495	COG0196	riboflavin kinase activity
Mag101_14500	COG0728	peptidoglycan biosynthetic process
Mag101_14510	COG0745	RESPONSE REGULATOR receiver
Mag101_14515	COG2205	protein histidine kinase activity
Mag101_14520	COG0268	Binds directly to 16S ribosomal RNA
Mag101_14525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Mag101_14530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Mag101_14535	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Mag101_14540	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Mag101_14545	COG0142	geranyltranstransferase activity
Mag101_14560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Mag101_14575	COG0629	single-stranded DNA binding
Mag101_14580	COG2814	Major facilitator Superfamily
Mag101_14655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Mag101_14670	COG0489	protein tyrosine kinase activity
Mag101_14670	COG3206	protein involved in exopolysaccharide biosynthesis
Mag101_14675	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Mag101_14700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Mag101_14705	COG1984	allophanate hydrolase subunit 2
Mag101_14715	COG3139	Protein of unknown function (DUF1315)
Mag101_14720	COG0203	ribosomal protein L17
Mag101_14725	COG0202	RNA polymerase activity
Mag101_14730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Mag101_14735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Mag101_14740	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Mag101_14745	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Mag101_14755	COG0200	Binds to the 23S rRNA
Mag101_14760	COG1841	ribosomal large subunit assembly
Mag101_14765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Mag101_14770	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Mag101_14775	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Mag101_14780	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Mag101_14785	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Mag101_14790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Mag101_14795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Mag101_14800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Mag101_14805	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Mag101_14810	COG0255	Belongs to the universal ribosomal protein uL29 family
Mag101_14815	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Mag101_14820	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Mag101_14825	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Mag101_14830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Mag101_14835	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Mag101_14840	COG0089	rRNA binding
Mag101_14845	COG0088	Forms part of the polypeptide exit tunnel
Mag101_14850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Mag101_14855	COG0051	transcription antitermination factor activity, RNA binding
Mag101_14880	COG2815	serine threonine protein kinase
Mag101_14880	COG0515	serine threonine protein kinase
Mag101_14890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Mag101_14895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Mag101_14900	COG0049	tRNA binding
Mag101_14905	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Mag101_14910	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Mag101_14915	COG0085	RNA polymerase activity
Mag101_14920	COG0222	ribosome binding
Mag101_14925	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Mag101_14930	COG0081	regulation of translation
Mag101_14935	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Mag101_14955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Mag101_14985	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Mag101_14995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Mag101_15000	COG1668	transmembrane transport
Mag101_15020	COG4989	oxidoreductase activity
Mag101_15050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Mag101_15055	COG2095	MarC family integral membrane protein
Mag101_15060	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
Mag101_15070	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Mag101_15075	COG0248	Ppx GppA phosphatase
Mag101_15080	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Mag101_15110	COG3046	protein related to deoxyribodipyrimidine photolyase
Mag101_15130	COG1252	NADH dehydrogenase
Mag101_15155	COG3273	potassium ion transport
Mag101_15155	COG0471	metal ion transport
Mag101_15160	COG0300	oxidoreductase activity
Mag101_15190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Mag101_15220	COG3291	Pkd domain containing protein
Mag101_15240	COG0366	Alpha amylase catalytic
Mag101_15275	COG1115	amino acid carrier protein
Mag101_15305	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Mag101_15345	COG0789	Transcriptional regulator
Mag101_15350	COG0625	glutathione transferase activity
Mag101_15360	COG4977	sequence-specific DNA binding
Mag101_15400	COG0366	Alpha amylase catalytic
Mag101_15405	COG1501	Belongs to the glycosyl hydrolase 31 family
Mag101_15410	COG1523	belongs to the glycosyl hydrolase 13 family
Mag101_15425	COG2133	pyrroloquinoline quinone binding
Mag101_15430	COG0366	Alpha amylase catalytic
Mag101_15435	COG0589	response to stress
Mag101_15450	COG0837	glucose binding
Mag101_15460	COG1472	Belongs to the glycosyl hydrolase 3 family
Mag101_15490	COG3833	ABC-type maltose transport systems, permease component
Mag101_15540	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Mag101_15545	COG1501	Belongs to the glycosyl hydrolase 31 family
Mag101_15585	COG2132	Multicopper oxidase
Mag101_15615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Mag101_15625	COG2217	Heavy metal translocating P-type atpase
Mag101_15680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Mag101_15685	COG0739	heme binding
Mag101_15690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Mag101_15695	COG0316	Belongs to the HesB IscA family
Mag101_15710	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Mag101_15725	COG0351	phosphomethylpyrimidine kinase
Mag101_15730	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Mag101_15750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Mag101_15755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Mag101_15760	COG5002	protein histidine kinase activity
Mag101_15760	COG5001	Diguanylate cyclase
Mag101_15780	COG4232	protein-disulfide reductase activity
Mag101_15790	COG0511	ligase activity, forming carbon-carbon bonds
Mag101_15800	COG2264	protein methyltransferase activity
Mag101_15820	COG0138	bifunctional purine biosynthesis protein purh
Mag101_15825	COG0151	Belongs to the GarS family
Mag101_15830	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
Mag101_15835	COG0179	Fumarylacetoacetate (FAA) hydrolase
Mag101_15840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Mag101_15845	COG2962	Rard protein
Mag101_15860	COG0126	phosphoglycerate kinase activity
Mag101_15875	COG1231	oxidoreductase activity
Mag101_15910	COG0730	response to heat
Mag101_15915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Mag101_15930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Mag101_15950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Mag101_15955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Mag101_15960	COG0640	Transcriptional regulator
Mag101_15965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Mag101_15970	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Mag101_15975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Mag101_15980	COG2885	chlorophyll binding
Mag101_15980	COG3047	cAMP biosynthetic process
Mag101_15990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Mag101_16000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Mag101_16015	COG2183	response to ionizing radiation
Mag101_16020	COG0564	pseudouridine synthase activity
Mag101_16025	COG3226	Transcriptional regulator
Mag101_16030	COG2977	Belongs to the P-Pant transferase superfamily
Mag101_16045	COG0010	Belongs to the arginase family
Mag101_16050	COG1228	amidohydrolase
Mag101_16055	COG2188	Transcriptional regulator
Mag101_16060	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Mag101_16065	COG2986	histidine ammonia-lyase
Mag101_16080	COG1595	DNA-templated transcription, initiation
Mag101_16085	COG0789	Transcriptional regulator
Mag101_16090	COG1960	acyl-CoA dehydrogenase activity
Mag101_16095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Mag101_16100	COG1024	Enoyl-CoA hydratase
Mag101_16130	COG2198	Histidine kinase
Mag101_16130	COG5002	protein histidine kinase activity
Mag101_16130	COG0784	Response regulator, receiver
Mag101_16170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Mag101_16180	COG0123	including yeast histone deacetylase and acetoin utilization protein
Mag101_16185	COG0427	acetyl-CoA hydrolase
Mag101_16190	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Mag101_16195	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Mag101_16205	COG1166	arginine decarboxylase activity
Mag101_16220	COG0010	Belongs to the arginase family
Mag101_16230	COG3214	Protein conserved in bacteria
Mag101_16240	COG1073	alpha beta
Mag101_16240	COG2226	methyltransferase
Mag101_16245	COG0156	8-amino-7-oxononanoate synthase activity
Mag101_16250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Mag101_16265	COG1404	Belongs to the peptidase S8 family
Mag101_16275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Mag101_16280	COG1045	serine acetyltransferase
Mag101_16290	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Mag101_16295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Mag101_16300	COG1509	lysine 2,3-aminomutase activity
Mag101_16335	COG0560	Phosphoserine phosphatase
Mag101_16355	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_16380	COG4771	TonB-dependent receptor
Mag101_16410	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Mag101_16425	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Mag101_16430	COG4942	peptidase
Mag101_16435	COG0793	Belongs to the peptidase S41A family
Mag101_16445	COG0107	imidazoleglycerol-phosphate synthase activity
Mag101_16450	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Mag101_16455	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Mag101_16460	COG0131	Imidazoleglycerol-phosphate dehydratase
Mag101_16470	COG4771	TonB-dependent receptor
Mag101_16525	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Mag101_16550	COG1902	pentaerythritol trinitrate reductase activity
Mag101_16550	COG0446	pyridine nucleotide-disulphide oxidoreductase
Mag101_16575	COG4771	TonB-dependent receptor
Mag101_16590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Mag101_16625	COG0129	dihydroxy-acid dehydratase activity
Mag101_16680	COG2197	response regulator
Mag101_16720	COG0714	Associated with various cellular activities
Mag101_16745	COG1218	3'(2'),5'-bisphosphate nucleotidase
Mag101_16760	COG1011	Hydrolase
Mag101_16765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Mag101_16770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Mag101_16785	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Mag101_16790	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Mag101_16820	COG2204	response regulator
Mag101_16825	COG3852	Histidine kinase
Mag101_16835	COG0174	glutamine synthetase
Mag101_16840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Mag101_16840	COG0301	tRNA thio-modification
Mag101_16855	COG0745	RESPONSE REGULATOR receiver
Mag101_16860	COG2205	protein histidine kinase activity
Mag101_16865	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Mag101_16895	COG3706	GGDEF domain
Mag101_16910	COG2326	polyphosphate kinase activity
Mag101_16920	COG2133	pyrroloquinoline quinone binding
Mag101_16930	COG0668	transmembrane transport
Mag101_16935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Mag101_16940	COG1505	serine-type exopeptidase activity
Mag101_16945	COG1490	D-aminoacyl-tRNA deacylase activity
Mag101_16970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Mag101_16975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Mag101_16980	COG0140	phosphoribosyl-ATP diphosphatase activity
Mag101_16985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Mag101_16990	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Mag101_17000	COG2226	methyltransferase
Mag101_17010	COG1785	Belongs to the alkaline phosphatase family
Mag101_17020	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Mag101_17025	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Mag101_17035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Mag101_17075	COG0281	malic enzyme
Mag101_17085	COG2918	glutathione biosynthetic process
Mag101_17090	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
Mag101_17095	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Mag101_17105	COG1346	cytolysis
Mag101_17130	COG0488	(ABC) transporter
Mag101_17140	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Mag101_17145	COG2363	Small membrane protein
Mag101_17155	COG2177	Part of the ABC transporter FtsEX involved in
Mag101_17160	COG2884	Cell division ATP-binding protein ftsE
Mag101_17165	COG0552	protein localization to endoplasmic reticulum
Mag101_17170	COG0742	ribosomal rna small subunit methyltransferase
Mag101_17175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Mag101_17185	COG2076	Multidrug Resistance protein
Mag101_17190	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Mag101_17195	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Mag101_17200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Mag101_17205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Mag101_17210	COG2003	Belongs to the UPF0758 family
Mag101_17215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Mag101_17225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Mag101_17230	COG1309	transcriptional regulator
Mag101_17240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Mag101_17245	COG0708	Exodeoxyribonuclease III
Mag101_17255	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Mag101_17260	COG1561	YicC-like family, N-terminal region
Mag101_17275	COG0183	Belongs to the thiolase family
Mag101_17290	COG1733	regulation of RNA biosynthetic process
Mag101_17295	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Mag101_17300	COG1028	Short-chain dehydrogenase reductase Sdr
Mag101_17310	COG1960	acyl-CoA dehydrogenase activity
Mag101_17340	COG1404	Belongs to the peptidase S8 family
Mag101_17365	COG0194	GDP metabolic process
Mag101_17370	COG1758	RNA polymerase activity
Mag101_17375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Mag101_17390	COG2261	transglycosylase associated protein
Mag101_17395	COG0583	DNA-binding transcription factor activity
Mag101_17400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Mag101_17415	COG1301	dicarboxylic acid transport
Mag101_17420	COG3161	chorismate lyase activity
Mag101_17425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Mag101_17445	COG3022	response to hydroperoxide
Mag101_17470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Mag101_17480	COG0573	inorganic phosphate transmembrane transporter activity
Mag101_17495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Mag101_17500	COG1607	acyl-coa hydrolase
Mag101_17515	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Mag101_17520	COG0210	DNA helicase
Mag101_17525	COG1737	Transcriptional regulator
Mag101_17530	COG2814	Major facilitator Superfamily
Mag101_17540	COG0435	Glutathione S-transferase
Mag101_17545	COG2259	Doxx family
Mag101_17560	COG1741	Belongs to the pirin family
Mag101_17600	COG3040	lipid binding
Mag101_17605	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Mag101_17620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Mag101_17625	COG1349	DNA-binding transcription factor activity
Mag101_17630	COG0508	dehydrogenase complex catalyzes the overall conversion of
Mag101_17645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Mag101_17650	COG4946	Tricorn protease homolog
Mag101_17650	COG1506	peptidase
Mag101_17650	COG0823	Involved in the tonB-independent uptake of proteins
Mag101_17655	COG4771	TonB-dependent receptor
Mag101_17660	COG0402	S-adenosylhomocysteine deaminase activity
Mag101_17670	COG1752	Esterase of the alpha-beta hydrolase superfamily
Mag101_17675	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Mag101_17680	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Mag101_17685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Mag101_17690	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Mag101_17700	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Mag101_17710	COG0356	it plays a direct role in the translocation of protons across the membrane
Mag101_17720	COG1475	DNA binding
Mag101_17725	COG1192	Involved in chromosome partitioning
Mag101_17735	COG0445	tRNA wobble uridine modification
Mag101_17745	COG0745	RESPONSE REGULATOR receiver
Mag101_17750	COG0642	Histidine kinase
Mag101_17755	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Mag101_17760	COG0706	membrane insertase activity
Mag101_17765	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Mag101_17770	COG0594	ribonuclease P activity
Mag101_17775	COG0230	Belongs to the bacterial ribosomal protein bL34 family