locus-tag	class	description
GNX18_00010	ENOG4105DEN	Luciferase family
GNX18_00040	ENOG4105EKQ	RNA-directed DNA polymerase
GNX18_00115	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
GNX18_00135	ENOG4105CFQ	glutamine synthetase
GNX18_00140	ENOG4105CTQ	phosphohexokinase
GNX18_00145	ENOG4105DFU	Cell wall formation (By similarity)
GNX18_00150	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GNX18_00170	ENOG4105N42	UPF0307 protein
GNX18_00175	ENOG4105CJW	magnesium transporter
GNX18_00180	ENOG41080Z8	PHOSPHOCARRIER protein
GNX18_00185	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GNX18_00190	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GNX18_00195	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GNX18_00200	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GNX18_00205	ENOG4108IUZ	ABC transporter
GNX18_00210	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GNX18_00225	ENOG4105C2X	Arabinose 5-phosphate isomerase
GNX18_00240	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GNX18_00245	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GNX18_00250	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GNX18_00255	ENOG4105C0H	protease
GNX18_00260	ENOG4107RIQ	Sulfate adenylate transferase
GNX18_00270	ENOG4105D6Z	AFG1 family ATPase
GNX18_00275	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GNX18_00280	ENOG4108UJD	30S ribosomal protein S9
GNX18_00290	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GNX18_00295	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GNX18_00300	ENOG4107MKT	Stringent starvation protein a
GNX18_00305	ENOG4105KB2	stringent starvation protein b
GNX18_00315	ENOG4105D0M	Protease HtpX homolog
GNX18_00320	ENOG4108V0P	LemA family
GNX18_00325	ENOG4105CHU	acetyl-coa acetyltransferase
GNX18_00330	ENOG4105W4M	Transport-associated protein
GNX18_00335	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GNX18_00340	ENOG41082RQ	UPF0102 protein
GNX18_00350	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GNX18_00365	ENOG4108V6E	Cell division protein mraZ
GNX18_00370	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GNX18_00380	ENOG4105CJN	penicillin-binding protein
GNX18_00385	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GNX18_00390	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GNX18_00395	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GNX18_00400	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GNX18_00405	ENOG4105CNI	cell division protein FtsW
GNX18_00410	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GNX18_00415	ENOG4105DFU	Cell wall formation (By similarity)
GNX18_00425	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GNX18_00430	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GNX18_00435	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GNX18_00440	ENOG4105DR5	peptidase
GNX18_00445	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GNX18_00455	ENOG4105M6F	mutator MutT protein
GNX18_00485	ENOG4105BZU	Histidine kinase
GNX18_00490	ENOG4105BZU	Histidine kinase
GNX18_00495	ENOG4105ECY	inositol monophosphatase
GNX18_00505	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GNX18_00515	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GNX18_00520	ENOG4108Z4V	iron-sulfur cluster assembly
GNX18_00525	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GNX18_00535	ENOG4108ZIT	Ferredoxin, 2FE-2S
GNX18_00540	ENOG4105WVQ	Fe-S assembly protein IscX
GNX18_00545	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GNX18_00550	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GNX18_00565	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GNX18_00570	ENOG4105CUT	histidyl-tRNA synthetase
GNX18_00575	ENOG4105N21	Membrane
GNX18_00580	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GNX18_00585	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GNX18_00590	ENOG4105C26	Dehydrogenase
GNX18_00595	ENOG4108R96	Methyltransferase, YaeB family
GNX18_00600	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GNX18_00620	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GNX18_00625	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
GNX18_00635	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GNX18_00645	ENOG4107QHF	type ii secretion system protein e
GNX18_00650	ENOG4105KHS	type IV fimbrial pilin protein
GNX18_00740	ENOG41082IR	Excinuclease ABC C subunit domain protein
GNX18_00755	ENOG4105DHP	deoxycytidine triphosphate deaminase
GNX18_00760	ENOG4105CBX	hi0933 family
GNX18_00775	ENOG4105VRT	cytoplasmic protein
GNX18_00790	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
GNX18_00830	ENOG4108KPZ	tonB-dependent Receptor
GNX18_00835	ENOG4105CGH	5'-nucleotidase
GNX18_00860	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GNX18_00865	ENOG4105C5R	Aminotransferase
GNX18_00870	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GNX18_00880	ENOG4108IG5	Transcriptional regulator
GNX18_00885	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GNX18_00895	ENOG4105D9N	nucleoside
GNX18_00900	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GNX18_00905	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GNX18_00910	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GNX18_00930	ENOG4107QUY	Guanine deaminase
GNX18_00935	ENOG4105VT2	5-hydroxyisourate hydrolase
GNX18_00955	ENOG4108HR6	Dehydrogenase
GNX18_00960	ENOG4105C7N	Xanthine uracil vitamin C permease
GNX18_00985	ENOG4105BZN	citrate synthase
GNX18_00990	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GNX18_00995	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GNX18_01000	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GNX18_01005	ENOG4105E33	succinate dehydrogenase
GNX18_01010	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GNX18_01015	ENOG4105C7S	Dehydrogenase
GNX18_01025	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GNX18_01030	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GNX18_01050	ENOG4105GRZ	Ycii-related protein
GNX18_01055	ENOG4105CHP	RNA polymerase
GNX18_01060	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
GNX18_01065	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
GNX18_01070	ENOG4105CH6	catalase
GNX18_01085	ENOG4107QZF	nitrite reductase NADPH large subunit
GNX18_01090	ENOG41077A9	carbonic anhydrase
GNX18_01130	ENOG4105CXN	decarboxylase
GNX18_01135	ENOG4105E0K	tonB-dependent siderophore receptor
GNX18_01165	ENOG4105WD1	Membrane
GNX18_01170	ENOG4108NEV	two component transcriptional regulator, LytTR family
GNX18_01185	ENOG4105CSU	acyl-Coa dehydrogenase
GNX18_01210	ENOG4105C58	cytochrome c oxidase accessory protein ccog
GNX18_01215	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GNX18_01230	ENOG4108VGI	doxx family
GNX18_01235	ENOG4105CC0	LysR family Transcriptional regulator
GNX18_01260	ENOG4108CIP	transcriptional regulator
GNX18_01270	ENOG4105D9R	oxidoreductase
GNX18_01295	ENOG4105NAE	bifunctional deaminase-reductase domain protein
GNX18_01310	ENOG4105F2I	Transposase
GNX18_01315	ENOG4105D5G	Transposase
GNX18_01325	ENOG4105R0I	Feruloyl esterase
GNX18_01330	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
GNX18_01335	ENOG4105C01	Dihydroxy-acid dehydratase
GNX18_01340	ENOG4105CT4	transporter
GNX18_01370	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GNX18_01375	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
GNX18_01395	ENOG4105R0I	Feruloyl esterase
GNX18_01405	ENOG4105R0I	Feruloyl esterase
GNX18_01410	ENOG4105CS2	ec 3.2.1.21
GNX18_01425	ENOG4105CSU	acyl-Coa dehydrogenase
GNX18_01430	ENOG4108RTU	Aldolase
GNX18_01450	ENOG4105C9F	isomerase
GNX18_01465	ENOG4105J1P	transposase, IS3 IS911 family protein
GNX18_01480	ENOG4108MGY	Histidine kinase
GNX18_01520	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GNX18_01525	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GNX18_01530	ENOG4105DBV	ornithine carbamoyltransferase
GNX18_01535	ENOG4105C8Y	Acetylornithine aminotransferase
GNX18_01540	ENOG4105M2J	Glutaredoxin
GNX18_01545	ENOG4108UQY	Iron-storage protein
GNX18_01555	ENOG4105W53	bacterioferritin-associated ferredoxin
GNX18_01560	ENOG4105D3R	alkyl hydroperoxide reductase
GNX18_01570	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GNX18_01575	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GNX18_01600	ENOG4108M3R	transcriptional activator CadC
GNX18_01620	ENOG4107T9C	Alpha amylase catalytic region
GNX18_01635	ENOG4105EUJ	GTP cyclohydrolase i
GNX18_01640	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GNX18_01645	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GNX18_01655	ENOG4108MP6	LysR family Transcriptional regulator
GNX18_01660	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GNX18_01665	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GNX18_01670	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GNX18_01680	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GNX18_01690	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GNX18_01695	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
GNX18_01705	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GNX18_01710	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GNX18_01715	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GNX18_01725	ENOG4105E96	Colicin v production protein
GNX18_01730	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GNX18_01735	ENOG4105C28	cystathionine
GNX18_01740	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GNX18_01750	ENOG4105F8C	transglutaminase domain-containing protein
GNX18_01770	ENOG4107QW3	Sucrose phosphorylase
GNX18_01775	ENOG4105C3Q	Glycosyl transferase, family 2
GNX18_01780	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
GNX18_01790	ENOG4105D07	Signal peptide peptidase, SppA
GNX18_01800	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GNX18_01805	ENOG4105K89	arsenate reductase
GNX18_01810	ENOG4107S2Z	UPF0761 membrane protein
GNX18_01815	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GNX18_01835	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GNX18_01855	ENOG4105CSU	acyl-Coa dehydrogenase
GNX18_01885	ENOG4105EJ9	Membrane
GNX18_01890	ENOG41082IR	Excinuclease ABC C subunit domain protein
GNX18_01895	ENOG41082YX	Transcriptional regulator, arsr family
GNX18_01905	ENOG4105D6J	arsenicaL-resistance protein
GNX18_01910	ENOG4105CAU	Arsenical resistance protein, ArsH
GNX18_01920	ENOG4105CBC	glutamate synthase
GNX18_01935	ENOG4105HDD	phospholipase
GNX18_01940	ENOG4105CPQ	Dehydrogenase
GNX18_01945	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GNX18_01960	ENOG4105C7K	acetolactate synthase
GNX18_01965	ENOG4105F7F	Chaperone
GNX18_01975	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GNX18_01980	ENOG4105C1G	acyl-Coa dehydrogenase
GNX18_01985	ENOG4105CC9	acyl-Coa dehydrogenase
GNX18_01990	ENOG4107ZSV	Receptor
GNX18_02000	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GNX18_02005	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GNX18_02010	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GNX18_02015	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GNX18_02020	ENOG4105F2Z	3-oxoadipate enol-lactonase
GNX18_02030	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GNX18_02035	ENOG4105MXW	flavin reductase domain protein, FMN-binding
GNX18_02040	ENOG4105E54	alpha-amylase
GNX18_02110	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GNX18_02115	ENOG4105CXN	decarboxylase
GNX18_02125	ENOG4105F8J	Adenylate Guanylate cyclase
GNX18_02130	ENOG4105WS7	Cation transport regulator
GNX18_02160	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
GNX18_02165	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GNX18_02170	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
GNX18_02175	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GNX18_02185	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GNX18_02190	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GNX18_02200	ENOG4105K9H	YciI-like protein
GNX18_02210	ENOG4105DB7	PHP domain protein
GNX18_02215	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GNX18_02225	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GNX18_02230	ENOG4105FE9	pseudouridine synthase
GNX18_02240	ENOG4105E0F	Histidine kinase
GNX18_02245	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GNX18_02255	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GNX18_02265	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GNX18_02270	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
GNX18_02275	ENOG4105KUZ	arsenate reductase
GNX18_02280	ENOG4105CSM	endonuclease III
GNX18_02285	ENOG4105CHM	Aminotransferase
GNX18_02290	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GNX18_02295	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GNX18_02300	ENOG4105CE9	30S ribosomal protein S2
GNX18_02305	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GNX18_02310	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GNX18_02315	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GNX18_02320	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GNX18_02325	ENOG4105KNE	Phosphatidate cytidylyltransferase
GNX18_02330	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GNX18_02335	ENOG4105DZP	Membrane-associated zinc metalloprotease
GNX18_02340	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GNX18_02355	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GNX18_02360	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GNX18_02365	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GNX18_02370	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GNX18_02375	ENOG4108JU6	CBS domain protein
GNX18_02380	ENOG4106KVJ	cytochrome C assembly protein
GNX18_02385	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GNX18_02390	ENOG4105K5M	30s ribosomal protein S16
GNX18_02395	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GNX18_02400	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GNX18_02405	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GNX18_02410	ENOG4105T95	Thiol disulfide interChange protein
GNX18_02415	ENOG4105D6E	homoserine dehydrogenase
GNX18_02420	ENOG4105D98	threonine synthase
GNX18_02425	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GNX18_02450	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GNX18_02460	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GNX18_02465	ENOG4105E5G	Alpha beta hydrolase fold
GNX18_02470	ENOG4105W49	UPF0434 protein
GNX18_02480	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GNX18_02485	ENOG4105CFH	Aspartokinase
GNX18_02490	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GNX18_02530	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GNX18_02535	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GNX18_02540	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GNX18_02545	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GNX18_02560	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GNX18_02565	ENOG4105EKE	dihydroorotase
GNX18_02570	ENOG4105CDH	Citrulline--aspartate ligase
GNX18_02575	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GNX18_02590	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GNX18_02640	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GNX18_02655	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
GNX18_02660	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
GNX18_02670	ENOG4108V1U	phospholipid-binding protein
GNX18_02680	ENOG41080UX	Methyltransferase
GNX18_02695	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GNX18_02705	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GNX18_02710	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GNX18_02745	ENOG4105EKQ	RNA-directed DNA polymerase
GNX18_02795	ENOG4105DCG	PHP domain protein
GNX18_02805	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GNX18_02810	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GNX18_02820	ENOG4107QSA	Oxaloacetate decarboxylase
GNX18_02825	ENOG4105D9Q	decarboxylase (Beta subunit)
GNX18_02830	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GNX18_02835	ENOG4105M85	Bola protein
GNX18_02840	ENOG4105EIF	outer membrane protein W
GNX18_02850	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
GNX18_02860	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GNX18_02885	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GNX18_02890	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GNX18_02905	ENOG4105YP7	UPF0270 protein
GNX18_02920	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GNX18_02930	ENOG4108BPE	-transporting atpase
GNX18_02935	ENOG4105C2M	dna polymerase I
GNX18_02940	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GNX18_02960	ENOG4105CHM	Aminotransferase
GNX18_02965	ENOG4105E0X	reductase
GNX18_02995	ENOG4105DA5	(ABC) transporter
GNX18_03000	ENOG4105E3A	(ABC) transporter
GNX18_03005	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GNX18_03010	ENOG4105F8J	Adenylate Guanylate cyclase
GNX18_03030	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GNX18_03040	ENOG4105NBR	Pectinesterase
GNX18_03050	ENOG4105CRK	lysyL-tRNA synthetase
GNX18_03065	ENOG4105HA9	of methanol dehydrogenase type
GNX18_03075	ENOG4108VWS	Yaeq family
GNX18_03080	ENOG4108VPT	UPF0234 protein
GNX18_03090	ENOG4108RG0	uracil-dna glycosylase
GNX18_03095	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GNX18_03100	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GNX18_03105	ENOG4105Y75	tpr repeat protein
GNX18_03115	ENOG4108IYU	L-aspartate oxidase
GNX18_03120	ENOG4105EMN	RNA polymerase sigma factor
GNX18_03125	ENOG41069E1	anti sigma-E protein RseA
GNX18_03130	ENOG4105VQK	sigma E regulatory protein, MucB RseB
GNX18_03135	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
GNX18_03140	ENOG4107S8C	mandelate racemase muconate lactonizing
GNX18_03145	ENOG4105KXI	murein peptide amidase A
GNX18_03150	ENOG4105C0H	protease
GNX18_03155	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GNX18_03160	ENOG4105C3F	Signal peptidase i
GNX18_03170	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GNX18_03175	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GNX18_03180	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GNX18_03185	ENOG4105BZU	Histidine kinase
GNX18_03190	ENOG4105C6T	cysteine synthase
GNX18_03195	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GNX18_03200	ENOG4105DXN	mazG family
GNX18_03205	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GNX18_03210	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GNX18_03220	ENOG41072GX	Peptidase M22 Glycoprotease
GNX18_03225	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GNX18_03230	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GNX18_03240	ENOG4105C31	Tryptophanyl-tRNA synthetase
GNX18_03265	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GNX18_03275	ENOG4105DH7	May be involved in recombination (By similarity)
GNX18_03285	ENOG4107XGZ	Hydrolase
GNX18_03290	ENOG4108Z66	YbaK ebsC protein
GNX18_03295	ENOG4105CIN	aminoacyl-histidine dipeptidase
GNX18_03300	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
GNX18_03320	ENOG4105MPN	Membrane
GNX18_03350	ENOG4105DDG	Cyanophycinase
GNX18_03355	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GNX18_03360	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GNX18_03365	ENOG4105DYB	Isoaspartyl dipeptidase
GNX18_03380	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GNX18_03385	ENOG4105CFQ	glutamine synthetase
GNX18_03395	ENOG4105E2K	Glycosyl transferase (Group 1
GNX18_03400	ENOG4107QVI	Methyltransferase, type 11
GNX18_03415	ENOG4108UW5	maltose o-acetyltransferase
GNX18_03420	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GNX18_03425	ENOG4108XM1	transcriptional regulator AsnC family
GNX18_03450	ENOG4107TYR	Glycosyl Transferase
GNX18_03460	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GNX18_03475	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GNX18_03490	ENOG4105UBK	short-chain dehydrogenase reductase
GNX18_03495	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GNX18_03500	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GNX18_03505	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GNX18_03510	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GNX18_03515	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GNX18_03525	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GNX18_03530	ENOG4105CAT	Cytidine monophosphate kinase
GNX18_03535	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GNX18_03540	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GNX18_03550	ENOG4105CFV	Tetratricopeptide repeat protein
GNX18_03555	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GNX18_03560	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GNX18_03570	ENOG4107UKG	Glycosyl transferase, family 4
GNX18_03590	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GNX18_03605	ENOG4105C22	threonyL-tRNA synthetase
GNX18_03610	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GNX18_03615	ENOG41082NX	50s ribosomal protein l35
GNX18_03620	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GNX18_03625	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GNX18_03630	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GNX18_03635	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GNX18_03665	ENOG4105E0Y	RtcB Protein
GNX18_03705	ENOG4105C1J	atp-dependent rna helicase
GNX18_03725	ENOG4108Z4X	TRANSCRIPTIONal
GNX18_03730	ENOG410624X	efflux transporter, rnd family, mfp subunit
GNX18_03735	ENOG4105BZS	acriflavin resistance protein
GNX18_03755	ENOG4108P9J	Phage shock protein A
GNX18_03775	ENOG4105F1G	UPF0441 protein
GNX18_03780	ENOG4106032	Glutathionylspermidine synthase
GNX18_03785	ENOG4105DR9	pseudouridine synthase
GNX18_03790	ENOG4105K5B	UPF0225 protein
GNX18_03810	ENOG4105WJG	Glutathione
GNX18_03825	ENOG4105EMN	RNA polymerase sigma factor
GNX18_03850	ENOG4108RXX	maleylacetoacetate isomerase
GNX18_03860	ENOG4105CGF	Aromatic amino acid aminotransferase
GNX18_03865	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
GNX18_03875	ENOG4105DGW	oligopeptidase A
GNX18_03885	ENOG4108YXU	transcriptional regulator AsnC family
GNX18_03900	ENOG4105K6V	RNA polymerase
GNX18_03910	ENOG4105EMU	Dehydrogenase
GNX18_03925	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GNX18_03945	ENOG4105C26	Dehydrogenase
GNX18_03950	ENOG4105EW9	transcriptional regulator AsnC family
GNX18_03975	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
GNX18_03990	ENOG4108V1U	phospholipid-binding protein
GNX18_04000	ENOG4108RRZ	Transcription elongation factor GreB
GNX18_04020	ENOG4108ZJT	translation initiation factor, Sui1
GNX18_04025	ENOG4105EYW	Ion transport protein
GNX18_04035	ENOG41069P5	Protein slyX homolog
GNX18_04060	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
GNX18_04065	ENOG4105EJQ	L-serine dehydratase
GNX18_04070	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GNX18_04075	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GNX18_04090	ENOG4106371	Methyltransferase
GNX18_04110	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GNX18_04115	ENOG4105KHC	sulfurtransferase
GNX18_04125	ENOG4105EN6	Membrane
GNX18_04130	ENOG4105C1G	acyl-Coa dehydrogenase
GNX18_04135	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GNX18_04150	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GNX18_04160	ENOG4108XM1	transcriptional regulator AsnC family
GNX18_04165	ENOG4105MIR	Phenylalanine 4-monooxygenase
GNX18_04170	ENOG4108JU8	Transcriptional regulator
GNX18_04190	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GNX18_04200	ENOG4105C3R	Methionine synthase
GNX18_04210	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GNX18_04215	ENOG4105GSQ	TM1410 hypothetical-related protein
GNX18_04225	ENOG4105EXG	Transcriptional regulator
GNX18_04235	ENOG4105CQ7	ATP-dependent helicase
GNX18_04240	ENOG4107MHI	Transcriptional regulator, MarR family
GNX18_04245	ENOG4105Q26	Siderophore-interacting protein
GNX18_04250	ENOG4105FQ6	thiopurine methyltransferase
GNX18_04260	ENOG4105F27	Major Facilitator
GNX18_04270	ENOG4107QWG	2-Nitropropane dioxygenase
GNX18_04280	ENOG4105EKQ	RNA-directed DNA polymerase
GNX18_04350	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
GNX18_04355	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
GNX18_04420	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GNX18_04460	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GNX18_04480	ENOG4105CGY	Dna recombination protein
GNX18_04495	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
GNX18_04500	ENOG4108Z4X	TRANSCRIPTIONal
GNX18_04515	ENOG4105C7K	acetolactate synthase
GNX18_04530	ENOG4108UQ8	endoribonuclease L-psp
GNX18_04540	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GNX18_04560	ENOG4108MN8	Membrane
GNX18_04575	ENOG4107V8I	Glycosyl transferases group 1
GNX18_04610	ENOG4105CHJ	isochorismatase hydrolase
GNX18_04620	ENOG4105C03	ribonuclease
GNX18_04625	ENOG4105EI2	Pseudouridine synthase
GNX18_04630	ENOG4108UHJ	MAF-like protein
GNX18_04635	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GNX18_04640	ENOG4105VGS	50s ribosomal protein l32
GNX18_04645	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GNX18_04650	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GNX18_04655	ENOG4105CHR	reductase
GNX18_04660	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GNX18_04665	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GNX18_04675	ENOG4105HHA	aminodeoxychorismate lyase
GNX18_04680	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GNX18_04685	ENOG4107QRG	dna polymerase iii
GNX18_04695	ENOG4105F8V	Hydrolase, tatD family
GNX18_04705	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GNX18_04710	ENOG4105C5S	asparaginyl-tRNA synthetase
GNX18_04720	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GNX18_04725	ENOG4108R6W	Transcriptional regulator, ARAC family
GNX18_04730	ENOG4105VIE	preprotein translocase, subunit YajC
GNX18_04735	ENOG4105K6H	D-cysteine desulfhydrase
GNX18_04740	ENOG4105BZG	amino acid carrier protein
GNX18_04745	ENOG4105CFQ	glutamine synthetase
GNX18_04750	ENOG4105CJP	fad dependent oxidoreductase
GNX18_04760	ENOG4105W1N	transcriptional regulator
GNX18_04770	ENOG4107R11	Transcriptional regulator
GNX18_04780	ENOG4105CRQ	synthase (Component I)
GNX18_04805	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GNX18_04815	ENOG4107QPN	acyl-Coa dehydrogenase
GNX18_04820	ENOG4105CYC	Transferase
GNX18_04825	ENOG4108DNC	Involved in acetate metabolism (By similarity)
GNX18_04830	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GNX18_04835	ENOG4105E08	Glycoside hydrolase, family 9
GNX18_04840	ENOG4107RET	Isocitrate lyase
GNX18_04855	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GNX18_04865	ENOG4105ECM	Sensor protein basS pmrB
GNX18_04870	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GNX18_04880	ENOG4108HPG	-acetyltransferase
GNX18_04885	ENOG4105EZE	Cupin 4 family protein
GNX18_04890	ENOG4107QTF	adenylosuccinate lyase
GNX18_04895	ENOG41075W9	High frequency lysogenization protein HflD homolog
GNX18_04905	ENOG4108R99	pseudouridine synthase
GNX18_04915	ENOG4105VEQ	Cold shock protein
GNX18_04920	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GNX18_04925	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GNX18_04930	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GNX18_04935	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
GNX18_04940	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GNX18_04945	ENOG4105C3M	thioredoxin reductase
GNX18_04950	ENOG4105CNU	cell division protein FtsK
GNX18_04955	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GNX18_04960	ENOG4105D1H	recombination factor protein RarA
GNX18_04965	ENOG4105WMR	Protein CrcB homolog
GNX18_04970	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GNX18_04975	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GNX18_04990	ENOG4105D05	Receptor
GNX18_04995	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
GNX18_05010	ENOG4105DNZ	Alpha Beta Hydrolase
GNX18_05045	ENOG4108S4H	thioesterase Superfamily protein
GNX18_05065	ENOG4105CQS	hydrogenase expression formation protein HypD
GNX18_05100	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
GNX18_05130	ENOG4105VN1	Heat shock protein
GNX18_05135	ENOG4105E2V	Glycosyltransferase 36
GNX18_05140	ENOG41068KF	Universal stress protein
GNX18_05150	ENOG4105DU1	integral membrane protein, terc
GNX18_05165	ENOG4105F2V	VRR-NUC domain-containing protein
GNX18_05190	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GNX18_05195	ENOG4105E0C	molybdate abc transporter
GNX18_05200	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GNX18_05205	ENOG4105F4R	Transcriptional regulator mode
GNX18_05210	ENOG4105BZS	acriflavin resistance protein
GNX18_05215	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GNX18_05220	ENOG4108IG5	Transcriptional regulator
GNX18_05225	ENOG4105CN1	protease
GNX18_05230	ENOG4105CGK	Exodeoxyribonuclease III
GNX18_05270	ENOG4105X5Z	General secretion pathway protein I
GNX18_05275	ENOG4105VWV	general secretion pathway protein h
GNX18_05280	ENOG4108VAU	general secretion pathway protein G
GNX18_05285	ENOG4105D7Q	type ii secretion system
GNX18_05290	ENOG4107QHF	type ii secretion system protein e
GNX18_05305	ENOG4105C10	Electron transfer flavoprotein
GNX18_05310	ENOG4105BZJ	Electron transfer flavoprotein
GNX18_05315	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GNX18_05340	ENOG4105C29	acyl-CoA thioesterase
GNX18_05380	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GNX18_05385	ENOG4105WH1	Two component transcriptional regulator luxr family
GNX18_05390	ENOG4105D4A	Cell wall formation (By similarity)
GNX18_05395	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GNX18_05400	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GNX18_05405	ENOG4105BZ1	(ABC) transporter
GNX18_05410	ENOG4109015	Biopolymer transport protein exbD tolR
GNX18_05420	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GNX18_05430	ENOG4105DDY	UPF0142 protein ycaO
GNX18_05435	ENOG4105CYW	agmatinase
GNX18_05470	ENOG4105BZU	Histidine kinase
GNX18_05505	ENOG4105DXD	2-methylcitrate dehydratase
GNX18_05545	ENOG4105EJC	lysr family transcriptional regulator
GNX18_05555	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GNX18_05570	ENOG4105CQ2	DNA polymerase
GNX18_05575	ENOG4105EEM	helicase
GNX18_05590	ENOG4105BZU	Histidine kinase
GNX18_05625	ENOG4105C7F	AcnD-accessory protein PrpF
GNX18_05630	ENOG4108I0Z	Aconitate hydratase
GNX18_05635	ENOG4105BZN	citrate synthase
GNX18_05640	ENOG4105CR4	methylisocitrate lyase
GNX18_05645	ENOG4108PVQ	transcriptional regulator
GNX18_05655	ENOG4105D60	lipoprotein releasing system transmembrane protein
GNX18_05660	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GNX18_05665	ENOG4105D60	lipoprotein releasing system transmembrane protein
GNX18_05685	ENOG4108VUY	thioesterase Superfamily protein
GNX18_05690	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
GNX18_05700	ENOG4105CJ2	(LipO)protein
GNX18_05705	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GNX18_05710	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GNX18_05720	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GNX18_05725	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GNX18_05730	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GNX18_05740	ENOG4108JA2	transcriptioN-repair coupling factor
GNX18_05755	ENOG4105VEQ	Cold shock protein
GNX18_05760	ENOG4105D64	Mechanosensitive ion channel
GNX18_05765	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
GNX18_05780	ENOG4108URH	decarboxylase
GNX18_05785	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GNX18_05800	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GNX18_05810	ENOG41081QV	Universal stress protein
GNX18_05815	ENOG4105C5H	ABC transporter
GNX18_05820	ENOG4107SC1	transglycosylase
GNX18_05835	ENOG4108ZF3	Phosphatase
GNX18_05840	ENOG4105D9P	serine threonine protein kinase
GNX18_05845	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GNX18_05850	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
GNX18_05855	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GNX18_05860	ENOG4105C7I	Dehydrogenase
GNX18_05865	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GNX18_05885	ENOG4107QVM	von Willebrand factor, type A
GNX18_05895	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GNX18_05900	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
GNX18_05920	ENOG4107T7U	Sulfatase
GNX18_05930	ENOG4107TAE	Glycosyl transferase (Group 1
GNX18_05945	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GNX18_05980	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GNX18_06000	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GNX18_06005	ENOG4105I08	Pseudouridine synthase
GNX18_06010	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GNX18_06025	ENOG4108ZGC	gaf domain protein
GNX18_06055	ENOG4105C8N	cysteinyl-tRNA synthetase
GNX18_06060	ENOG4105CX6	glutaminyL-tRNA synthetase
GNX18_06065	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GNX18_06070	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GNX18_06075	ENOG4105CHH	sulfate transporter
GNX18_06080	ENOG4107B2H	carbonic anhydrase
GNX18_06085	ENOG4105C5Q	Transcriptional regulator
GNX18_06090	ENOG4105D5Q	Arginine ornithine antiporter
GNX18_06095	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GNX18_06110	ENOG4107QIJ	Aconitate hydratase 2
GNX18_06155	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
GNX18_06180	ENOG4105D3R	alkyl hydroperoxide reductase
GNX18_06195	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
GNX18_06205	ENOG4105CHH	sulfate transporter
GNX18_06220	ENOG41080HT	Transcriptional regulator, arsr family
GNX18_06225	ENOG4105MD1	YeeE YedE family protein
GNX18_06240	ENOG4105C4R	Atp-dependent dna helicase
GNX18_06260	ENOG4105ERU	peptidase
GNX18_06270	ENOG4105E09	nadh pyrophosphatase
GNX18_06280	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GNX18_06285	ENOG4107RZZ	dna polymerase iii epsilon subunit
GNX18_06290	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GNX18_06295	ENOG4105D1A	Methyltransferase
GNX18_06300	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GNX18_06305	ENOG4105E9H	Lytic Murein transglycosylase
GNX18_06310	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GNX18_06315	ENOG4105K70	DNA-binding protein
GNX18_06320	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GNX18_06325	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GNX18_06330	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GNX18_06335	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GNX18_06345	ENOG4105CHU	acetyl-coa acetyltransferase
GNX18_06350	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GNX18_06355	ENOG4107RX2	synthase
GNX18_06360	ENOG4105ID8	Transcriptional regulator, ARAC family
GNX18_06370	ENOG4108ZNX	Heat shock protein
GNX18_06390	ENOG4105DC8	reductase
GNX18_06400	ENOG4106K28	UPF0283 membrane protein
GNX18_06405	ENOG4105CM6	amino acid regulated cytosolic protein
GNX18_06425	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GNX18_06430	ENOG4105CUZ	uba thif-type nad fad binding protein
GNX18_06440	ENOG4105EYA	deoxyribonuclease
GNX18_06445	ENOG4105CHR	reductase
GNX18_06455	ENOG4105C09	Bile acid
GNX18_06460	ENOG4105H3G	oxidoreductase
GNX18_06470	ENOG4105D7A	ATP-binding protein
GNX18_06500	ENOG4105CEY	Amp-dependent synthetase and ligase
GNX18_06510	ENOG4105CSU	acyl-Coa dehydrogenase
GNX18_06515	ENOG4108ZX5	transcriptional regulator
GNX18_06525	ENOG4105C9Q	fumarate hydratase class II
GNX18_06535	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GNX18_06540	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GNX18_06550	ENOG4108M1T	Cytochrome c-type biogenesis protein
GNX18_06555	ENOG4105KWW	Biogenesis protein
GNX18_06585	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GNX18_06590	ENOG4107QX9	Thiol disulfide interChange protein
GNX18_06595	ENOG4105DA4	cytochrome c-type biogenesis protein
GNX18_06600	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GNX18_06610	ENOG41060IM	Heme exporter protein
GNX18_06615	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
GNX18_06620	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
GNX18_06645	ENOG4105D44	asparaginase
GNX18_06710	ENOG4105BZS	acriflavin resistance protein
GNX18_06725	ENOG4107S6Z	Na H antiporter
GNX18_06730	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GNX18_06745	ENOG4106G6Q	Transcriptional regulator
GNX18_06750	ENOG4105DTQ	mandelate racemase muconate lactonizing
GNX18_06760	ENOG4108KPZ	tonB-dependent Receptor
GNX18_06765	ENOG4105EWT	decarboxylase family
GNX18_06770	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GNX18_06775	ENOG4108Z4U	Ferredoxin
GNX18_06800	ENOG4105C8P	)-transporter
GNX18_06840	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GNX18_06845	ENOG4105DUM	transcriptional regulator, lysR family
GNX18_06880	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GNX18_06885	ENOG4105DCF	alanine dehydrogenase
GNX18_06890	ENOG4105EW9	transcriptional regulator AsnC family
GNX18_06920	ENOG41065RQ	ADP-ribosylation crystallin J1
GNX18_06945	ENOG4105CNA	YD repeat protein
GNX18_06975	ENOG4105CNA	YD repeat protein
GNX18_06980	ENOG4108UVJ	appr-1-p processing domain protein
GNX18_06985	ENOG4105CK7	Sodium proline symporter
GNX18_06990	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GNX18_06995	ENOG4108UJV	acyl-CoA thioesterase i
GNX18_07000	ENOG4108I0Y	(ABC) transporter
GNX18_07005	ENOG4105CV6	ABC transporter, permease
GNX18_07010	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GNX18_07015	ENOG4105CYP	glycoside hydrolase, family
GNX18_07020	ENOG4105CX8	fg-gap repeat protein
GNX18_07055	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
GNX18_07060	ENOG4105E4I	Glycoside hydrolase family 28
GNX18_07065	ENOG4105F5H	Glycosyl Hydrolase Family 88
GNX18_07085	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GNX18_07110	ENOG4105CHU	acetyl-coa acetyltransferase
GNX18_07115	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
GNX18_07125	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GNX18_07130	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GNX18_07140	ENOG4105C1G	acyl-Coa dehydrogenase
GNX18_07155	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GNX18_07160	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GNX18_07165	ENOG4105D9M	gamma-glutamylcysteine synthetase
GNX18_07175	ENOG4108JJA	ABC, transporter
GNX18_07195	ENOG4105E5W	Transporter
GNX18_07205	ENOG4105EBR	Carboxylesterase
GNX18_07215	ENOG4105CD8	aminopeptidase N
GNX18_07220	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GNX18_07230	ENOG410689M	(LipO)protein
GNX18_07235	ENOG4105WXT	Conserved Protein
GNX18_07240	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GNX18_07245	ENOG4108K5P	(LipO)protein
GNX18_07255	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GNX18_07260	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GNX18_07265	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GNX18_07270	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GNX18_07275	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GNX18_07280	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GNX18_07285	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GNX18_07290	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GNX18_07295	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GNX18_07300	ENOG4106J46	endo-1,4-beta-xylanase (EC 3.2.1.8)
GNX18_07320	ENOG4108RMV	DegV Family
GNX18_07335	ENOG4105EUZ	Beta-lactamase domain protein
GNX18_07340	ENOG4107RZC	phospholipase d
GNX18_07350	ENOG4105ENH	Sulfatase
GNX18_07475	ENOG4105EKQ	RNA-directed DNA polymerase
GNX18_07485	ENOG4108ETH	Formylglycinamide ribotide synthetase
GNX18_07490	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GNX18_07495	ENOG4106Z5D	Glycoside Hydrolase Family 43
GNX18_07510	ENOG4105CXG	d-lactate dehydrogenase
GNX18_07530	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GNX18_07535	ENOG4105DX0	Hemolysin A
GNX18_07545	ENOG41090A4	Pterin carbinolamine dehydratase
GNX18_07555	ENOG4107GFK	fumarate
GNX18_07565	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GNX18_07585	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GNX18_07600	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GNX18_07605	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GNX18_07625	ENOG4105DG7	nitrate ABC transporter
GNX18_07630	ENOG4105D7T	ABC transporter
GNX18_07645	ENOG4105D06	uba thif-type nad fad binding protein
GNX18_07650	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GNX18_07655	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GNX18_07660	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GNX18_07670	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GNX18_07675	ENOG4105C26	Dehydrogenase
GNX18_07685	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GNX18_07690	ENOG4105CY0	Metallo-Beta-Lactamase
GNX18_07695	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GNX18_07700	ENOG4105C0B	DNA polymerase III (alpha subunit)
GNX18_07710	ENOG4108Z0R	Transferase
GNX18_07715	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GNX18_07725	ENOG4105HEI	LysR family (Transcriptional regulator
GNX18_07735	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GNX18_07745	ENOG41062JF	Transcriptional regulator
GNX18_07755	ENOG4105KNA	-acetyltransferase
GNX18_07775	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GNX18_07790	ENOG4105EKQ	RNA-directed DNA polymerase
GNX18_07820	ENOG4108JJ7	ABC transporter
GNX18_07850	ENOG4105D5Q	Arginine ornithine antiporter
GNX18_07855	ENOG4105CEU	Arginine dihydrolase
GNX18_07860	ENOG4105DFD	Na H antiporter
GNX18_07865	ENOG4105E09	nadh pyrophosphatase
GNX18_07875	ENOG4107QR8	Thioredoxin
GNX18_07895	ENOG4108YYH	Nadph-dependent fmn reductase
GNX18_07905	ENOG4108Z6B	deaminase
GNX18_07910	ENOG4105DHI	Methyltransferase
GNX18_07920	ENOG4105E2D	ec 3.2.1.52
GNX18_07935	ENOG4108K5H	permease YjgP YjgQ family protein
GNX18_07940	ENOG4108M8S	permease YjgP YjgQ family protein
GNX18_07945	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GNX18_07960	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GNX18_07965	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GNX18_07970	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GNX18_07975	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GNX18_07980	ENOG4105GKE	subunit e
GNX18_07985	ENOG4107QIZ	NADH dehydrogenase
GNX18_07990	ENOG4108IEH	NADH dehydrogenase subunit g
GNX18_07995	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GNX18_08000	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GNX18_08005	ENOG4107UFS	subunit j
GNX18_08010	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GNX18_08015	ENOG4105D65	subunit l
GNX18_08020	ENOG4105C8S	subunit m
GNX18_08025	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GNX18_08040	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GNX18_08055	ENOG4105WP7	tRNA pseudouridine synthase C
GNX18_08060	ENOG4105DVT	helicase
GNX18_08080	ENOG4107QP8	phosphohexose isomerase
GNX18_08085	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
GNX18_08090	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
GNX18_08100	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
GNX18_08105	ENOG4105CNT	hydrolase family 2
GNX18_08110	ENOG4107EJG	GntR family transcriptional regulator
GNX18_08115	ENOG4105C01	Dihydroxy-acid dehydratase
GNX18_08120	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
GNX18_08125	ENOG4108RTU	Aldolase
GNX18_08135	ENOG4107QX8	SPFH domain, Band 7 family protein
GNX18_08170	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GNX18_08175	ENOG4105C9A	Phoh family
GNX18_08185	ENOG4108JU5	Magnesium and cobalt efflux protein
GNX18_08195	ENOG4105ECP	epimerase
GNX18_08215	ENOG4105C8T	Leucyl-tRNA synthetase
GNX18_08225	ENOG4105DJF	DNA polymerase III, delta' subunit
GNX18_08230	ENOG4105CHM	Aminotransferase
GNX18_08235	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GNX18_08245	ENOG4108YZN	class I peptide chain release factor
GNX18_08250	ENOG4105C94	Transporter
GNX18_08255	ENOG4105C94	Transporter
GNX18_08270	ENOG4107QN1	sodium solute
GNX18_08285	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GNX18_08295	ENOG4105BZU	Histidine kinase
GNX18_08305	ENOG41065HY	1,4-beta-cellobiosidase
GNX18_08310	ENOG4107QUA	Cellulase (glycosyl hydrolase family 5)
GNX18_08320	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
GNX18_08325	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GNX18_08330	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GNX18_08335	ENOG41084BA	UPF0250 protein
GNX18_08340	ENOG4105DZ1	carboxypeptidase
GNX18_08345	ENOG4105K6T	rare lipoprotein A
GNX18_08350	ENOG4105CVE	Lytic murein transglycosylase
GNX18_08355	ENOG4105CNI	cell division protein FtsW
GNX18_08360	ENOG4105CJN	penicillin-binding protein
GNX18_08365	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GNX18_08375	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GNX18_08380	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GNX18_08395	ENOG4105CGZ	zinc metallopeptidase
GNX18_08400	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
GNX18_08415	ENOG4105C03	ribonuclease
GNX18_08420	ENOG4108Z03	MAF-like protein
GNX18_08425	ENOG4105VQ7	Rod shape-determining protein MreD
GNX18_08430	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GNX18_08440	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GNX18_08445	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GNX18_08450	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GNX18_08465	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
GNX18_08480	ENOG4107QI1	Mate efflux family protein
GNX18_08495	ENOG4105PGM	cation diffusion facilitator family transporter
GNX18_08500	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GNX18_08505	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GNX18_08510	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GNX18_08520	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GNX18_08525	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GNX18_08535	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GNX18_08540	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GNX18_08545	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GNX18_08550	ENOG4105C3G	gtp-binding protein
GNX18_08555	ENOG4105QYV	Membrane
GNX18_08595	ENOG4105CA9	Pyruvate kinase
GNX18_08605	ENOG4108UHU	Aldolase
GNX18_08610	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
GNX18_08615	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GNX18_08620	ENOG4105C01	Dihydroxy-acid dehydratase
GNX18_08630	ENOG4107QP8	phosphohexose isomerase
GNX18_08635	ENOG4105ETE	Transcriptional regulator (LacI family
GNX18_08640	ENOG4105EDR	glucose galactose transporter
GNX18_08645	ENOG4105CE4	GlcNAc 6-P deacetylase
GNX18_08650	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GNX18_08655	ENOG4105RD7	BadF BadG BcrA BcrD
GNX18_08670	ENOG4105XT2	Transcriptional regulator
GNX18_08675	ENOG4105CXT	aspartate transcarbamylase
GNX18_08680	ENOG4105CJB	Exodeoxyribonuclease I
GNX18_08755	ENOG4105EZV	Transcriptional regulator
GNX18_08760	ENOG4105C75	arginyL-tRNA synthetase
GNX18_08770	ENOG4105BZU	Histidine kinase
GNX18_08775	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GNX18_08780	ENOG4105C5X	domain protein
GNX18_08785	ENOG4105BZU	Histidine kinase
GNX18_08805	ENOG4105CIY	formyltetrahydrofolate deformylase
GNX18_08810	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
GNX18_08815	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GNX18_08820	ENOG4105DZ2	Transcriptional regulator
GNX18_08825	ENOG4107E2E	PKHD-type hydroxylase
GNX18_08830	ENOG4108ESX	Receptor
GNX18_08840	ENOG4105C1J	atp-dependent rna helicase
GNX18_08845	ENOG41084CK	capsule polysaccharide
GNX18_08865	ENOG4105CY0	Metallo-Beta-Lactamase
GNX18_08935	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
GNX18_08940	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GNX18_08950	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GNX18_08960	ENOG4107V1M	polysaccharide export protein
GNX18_08975	ENOG41090SZ	ABC-2 type transporter
GNX18_08985	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GNX18_08990	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GNX18_09020	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
GNX18_09025	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
GNX18_09045	ENOG4105MQ3	flagellar protein FliS
GNX18_09050	ENOG4105DTS	flagellar hook-associated
GNX18_09055	ENOG4105I03	Flagellin
GNX18_09060	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GNX18_09065	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GNX18_09070	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GNX18_09080	ENOG4108JIR	Flagellum-specific ATP synthase
GNX18_09100	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GNX18_09105	ENOG4105DD5	Flagellar motor switch protein
GNX18_09110	ENOG4105K0P	flagellar biosynthesis protein
GNX18_09115	ENOG4105CN7	Flagellar biosynthetic protein FliP
GNX18_09125	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GNX18_09130	ENOG4105DTJ	flagellar hook-associated protein
GNX18_09135	ENOG4105E1Q	flagellar hook-associated protein
GNX18_09140	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GNX18_09145	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GNX18_09155	ENOG4105CGA	flagellar basal-body rod protein FlgG
GNX18_09160	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GNX18_09165	ENOG4105BZE	flagellar hook protein, FlgE
GNX18_09170	ENOG4105W00	Flagellar hook capping protein
GNX18_09175	ENOG4108ZC9	flagellar basal-body rod protein flgc
GNX18_09180	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GNX18_09190	ENOG4105M9M	anti-sigma28 factor FlgM
GNX18_09200	ENOG4105D58	Diguanylate phosphodiesterase
GNX18_09205	ENOG41067XB	TonB family
GNX18_09210	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GNX18_09215	ENOG4105D7B	Flagellar biosynthesis protein flha
GNX18_09220	ENOG4105D00	flagellar biosynthetic protein flhB
GNX18_09225	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GNX18_09230	ENOG4108VYJ	response regulator receiver protein
GNX18_09235	ENOG4105C8Q	Methyl-accepting chemotaxis
GNX18_09240	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GNX18_09245	ENOG4105BZU	Histidine kinase
GNX18_09250	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GNX18_09255	ENOG4108V3W	Chemotaxis protein, CheW
GNX18_09260	ENOG4105CBS	Chea signal transduction histidine kinase
GNX18_09265	ENOG4105ER2	Ompa motb domain protein
GNX18_09270	ENOG4107RD7	Flagellar Motor Protein, MotA
GNX18_09280	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GNX18_09295	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GNX18_09300	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GNX18_09320	ENOG410903C	(LipO)protein
GNX18_09330	ENOG4105E18	UPF0276 protein
GNX18_09340	ENOG4105CQ7	ATP-dependent helicase
GNX18_09345	ENOG4105DUX	Transporter
GNX18_09370	ENOG4108ZZ3	UPF0260 protein
GNX18_09375	ENOG4105VNG	YcgL domain-containing protein
GNX18_09385	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GNX18_09390	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GNX18_09395	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GNX18_09400	ENOG4108SF5	RNA Polymerase
GNX18_09415	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GNX18_09420	ENOG4108KPZ	tonB-dependent Receptor
GNX18_09425	ENOG4105D05	Receptor
GNX18_09440	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GNX18_09455	ENOG4105DUX	Transporter
GNX18_09460	ENOG4105HF0	Membrane
GNX18_09465	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GNX18_09470	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GNX18_09475	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GNX18_09480	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GNX18_09485	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GNX18_09490	ENOG4105CHV	Transcription elongation factor NusA
GNX18_09495	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GNX18_09520	ENOG4105CIS	alcohol dehydrogenase
GNX18_09600	ENOG4108ZAF	Molybdopterin
GNX18_09605	ENOG4105M00	molybdopterin converting factor, subunit 1
GNX18_09610	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GNX18_09615	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GNX18_09620	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GNX18_09625	ENOG4105CA9	Pyruvate kinase
GNX18_09635	ENOG4105C7N	Xanthine uracil vitamin C permease
GNX18_09640	ENOG4105CDY	transcriptional regulatory protein
GNX18_09645	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GNX18_09675	ENOG4107EJC	Preprotein translocase subunit SecG
GNX18_09680	ENOG4105CP7	Triose-phosphate isomerase
GNX18_09685	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GNX18_09690	ENOG4105EEI	dihydropteroate synthase
GNX18_09695	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GNX18_09700	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GNX18_09705	ENOG4105HBR	Rna-binding protein
GNX18_09710	ENOG4107TDE	lipolytic protein G-D-S-L family
GNX18_09720	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GNX18_09725	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GNX18_09735	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GNX18_09755	ENOG4105C7W	Xanthine dehydrogenase
GNX18_09775	ENOG4107R3J	Transporter
GNX18_09780	ENOG4107R3J	Transporter
GNX18_09785	ENOG4105D9P	serine threonine protein kinase
GNX18_09790	ENOG4107QZF	nitrite reductase NADPH large subunit
GNX18_09795	ENOG4105WZK	nitrite reductase NADPH small subunit
GNX18_09805	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GNX18_09810	ENOG41061CK	Antibiotic biosynthesis monooxygenase
GNX18_09815	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GNX18_09820	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
GNX18_09825	ENOG4105DA5	(ABC) transporter
GNX18_09830	ENOG4105E3A	(ABC) transporter
GNX18_09850	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
GNX18_09860	ENOG4107QWP	ABC-2 type transporter
GNX18_09865	ENOG4105CJ1	ABC, transporter
GNX18_09875	ENOG41086KC	Transcriptional regulator
GNX18_09880	ENOG4108XDW	curli assembly protein CsgE
GNX18_09885	ENOG4108WYR	Curli production assembly transport component, CsgF
GNX18_09890	ENOG4105P8Q	Curli production assembly transport component CsgG
GNX18_09915	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GNX18_09920	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GNX18_09930	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GNX18_09935	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GNX18_09945	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GNX18_09950	ENOG4105CFG	Acts as a chaperone (By similarity)
GNX18_09955	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GNX18_09960	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GNX18_09970	ENOG41090R7	Ferric uptake
GNX18_09975	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GNX18_09980	ENOG4105VDB	UPF0125 protein
GNX18_09985	ENOG4108Z1B	Cyclase dehydrase
GNX18_09990	ENOG4105C8J	)-transporter
GNX18_09995	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GNX18_10000	ENOG4105C8J	)-transporter
GNX18_10005	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GNX18_10025	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GNX18_10045	ENOG4105CVR	type I restriction-modification system
GNX18_10050	ENOG4105CGY	Dna recombination protein
GNX18_10055	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
GNX18_10060	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GNX18_10075	ENOG4105KPY	Small multidrug resistance protein
GNX18_10095	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GNX18_10120	ENOG4106IUH	DTW domain containing protein
GNX18_10130	ENOG4105EIF	outer membrane protein W
GNX18_10150	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
GNX18_10165	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GNX18_10170	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GNX18_10185	ENOG4105CNM	Receptor
GNX18_10210	ENOG4108IA2	Sodium pantothenate symporter
GNX18_10215	ENOG4105KME	endoribonuclease L-psp
GNX18_10225	ENOG4106KNT	transcriptional regulator
GNX18_10235	ENOG4105E2D	ec 3.2.1.52
GNX18_10325	ENOG4105M2Z	protein tyrosine serine phosphatase
GNX18_10355	ENOG4107QUT	magnesium and cobalt transport protein CorA
GNX18_10365	ENOG4105DS1	cytochrome b561
GNX18_10370	ENOG4108YYC	ycei family
GNX18_10375	ENOG4105CK7	Sodium proline symporter
GNX18_10385	ENOG4105CZK	Aspartate kinase
GNX18_10390	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
GNX18_10415	ENOG4105D9P	serine threonine protein kinase
GNX18_10420	ENOG4105D9P	serine threonine protein kinase
GNX18_10460	ENOG4105E54	alpha-amylase
GNX18_10465	ENOG4105C0H	protease
GNX18_10475	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GNX18_10480	ENOG4105E1F	short-chain dehydrogenase reductase
GNX18_10500	ENOG4105KA0	thioesterase Superfamily protein
GNX18_10510	ENOG4105C5X	domain protein
GNX18_10520	ENOG4105ETE	Transcriptional regulator (LacI family
GNX18_10550	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
GNX18_10555	ENOG4105CXK	mandelate racemase muconate lactonizing
GNX18_10560	ENOG4105E08	Glycoside hydrolase, family 9
GNX18_10565	ENOG4105QV4	Tryptophan halogenase
GNX18_10595	ENOG4107SET	aldo keto reductase
GNX18_10600	ENOG4105E08	Glycoside hydrolase, family 9
GNX18_10615	ENOG4106RHG	Yeca family
GNX18_10620	ENOG4105CG3	alpha amylase, catalytic region
GNX18_10655	ENOG4105BZG	amino acid carrier protein
GNX18_10660	ENOG4107EJG	GntR family transcriptional regulator
GNX18_10695	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
GNX18_10710	ENOG4105ETE	Transcriptional regulator (LacI family
GNX18_10725	ENOG4105EAA	nucleoside
GNX18_10760	ENOG4105EX0	alpha-galactosidase
GNX18_10785	ENOG4105HY2	Glycosidase related protein
GNX18_10795	ENOG4105ETE	Transcriptional regulator (LacI family
GNX18_10810	ENOG4107VIJ	nudix hydrolase
GNX18_10820	ENOG4105KU2	hydrolase family 5
GNX18_10880	ENOG4108RZE	Tetr family transcriptional regulator
GNX18_10890	ENOG4108IUK	alpha amylase, catalytic
GNX18_10895	ENOG4105CJQ	hydrolase, family 31
GNX18_10900	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GNX18_10925	ENOG4105DHQ	Histidine kinase
GNX18_10930	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GNX18_10960	ENOG4107T9C	Alpha amylase catalytic region
GNX18_10975	ENOG4107T9C	Alpha amylase catalytic region
GNX18_10980	ENOG4105Q9Y	Universal stress protein
GNX18_10985	ENOG4105QV4	Tryptophan halogenase
GNX18_11025	ENOG4105QV4	Tryptophan halogenase
GNX18_11075	ENOG4105QV4	Tryptophan halogenase
GNX18_11100	ENOG4105EG2	ABC transporter, permease
GNX18_11120	ENOG4107RGH	Aldehyde dehydrogenase
GNX18_11135	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GNX18_11140	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GNX18_11145	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GNX18_11150	ENOG4105EHG	Permease protein
GNX18_11160	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GNX18_11200	ENOG4105E3B	Multicopper oxidase
GNX18_11215	ENOG4105C59	p-type ATPase
GNX18_11220	ENOG4108M4U	conserved membrane protein
GNX18_11270	ENOG4105DR5	peptidase
GNX18_11275	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GNX18_11280	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GNX18_11295	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GNX18_11305	ENOG4108YXA	Membrane
GNX18_11315	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GNX18_11320	ENOG4105DKK	Benzoate
GNX18_11330	ENOG4105D52	delta-aminolevulinic acid dehydratase
GNX18_11345	ENOG4105BZ4	penicillin-binding protein
GNX18_11355	ENOG4105BZU	Histidine kinase
GNX18_11375	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GNX18_11380	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GNX18_11385	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GNX18_11390	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GNX18_11395	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GNX18_11405	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GNX18_11410	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GNX18_11415	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GNX18_11425	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
GNX18_11430	ENOG4108UKZ	OsmC family
GNX18_11435	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GNX18_11440	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GNX18_11455	ENOG4105DGW	oligopeptidase A
GNX18_11460	ENOG4105CKI	cobalamin synthesis protein
GNX18_11480	ENOG4105CKI	cobalamin synthesis protein
GNX18_11485	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GNX18_11505	ENOG4105CC0	LysR family Transcriptional regulator
GNX18_11520	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GNX18_11525	ENOG4107QYG	anthranilate phosphoribosyltransferase
GNX18_11530	ENOG4105DDQ	anthranilate synthase
GNX18_11540	ENOG4105CRQ	synthase (Component I)
GNX18_11545	ENOG4105DJV	ribulose-phosphate 3-epimerase
GNX18_11550	ENOG4108S0S	Nucleotidyl transferase
GNX18_11555	ENOG4105EHM	Aminoglycoside phosphotransferase
GNX18_11560	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GNX18_11565	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GNX18_11570	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GNX18_11575	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GNX18_11580	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GNX18_11585	ENOG4105CMR	udp-glucose 4-epimerase
GNX18_11590	ENOG4105CYN	Serine protein kinase
GNX18_11595	ENOG4106AKX	UPF0229 protein
GNX18_11600	ENOG4105ED1	spovr family
GNX18_11605	ENOG4108WQH	regulatoR
GNX18_11610	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GNX18_11615	ENOG4105CHR	reductase
GNX18_11635	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GNX18_11640	ENOG4105EB3	Histidine kinase
GNX18_11650	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GNX18_11655	ENOG4107ZVW	dihydroneopterin aldolase
GNX18_11660	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GNX18_11665	ENOG4105VCC	30S ribosomal protein S21
GNX18_11670	ENOG4105KTH	gatB Yqey
GNX18_11675	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GNX18_11685	ENOG41080IJ	Diacylglycerol kinase
GNX18_11705	ENOG4105DZR	Type I site-specific deoxyribonuclease
GNX18_11710	ENOG4105CVR	type I restriction-modification system
GNX18_11750	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
GNX18_11755	ENOG4105DXI	Major Facilitator superfamily
GNX18_11765	ENOG4105C0D	helicase
GNX18_11775	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GNX18_11780	ENOG4105CMG	Carbohydrate kinase
GNX18_11785	ENOG4105C93	Xylose Isomerase
GNX18_11790	ENOG4105ETE	Transcriptional regulator (LacI family
GNX18_11805	ENOG4108YYH	Nadph-dependent fmn reductase
GNX18_11810	ENOG4105EUB	pirin domain protein
GNX18_11820	ENOG4107TDE	lipolytic protein G-D-S-L family
GNX18_11865	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GNX18_11870	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
GNX18_11875	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GNX18_11885	ENOG4105D2H	Uronic isomerase
GNX18_11890	ENOG4105DEI	Mannitol dehydrogenase
GNX18_11905	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GNX18_11935	ENOG4105F5H	Glycosyl Hydrolase Family 88
GNX18_11940	ENOG4105D05	Receptor
GNX18_11950	ENOG41073TP	transcriptional regulator
GNX18_11955	ENOG4105CTX	dehydratase
GNX18_11965	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GNX18_11980	ENOG4105EGS	Mechanosensitive ion channel
GNX18_12000	ENOG4105EVZ	LysR family transcriptional regulator
GNX18_12020	ENOG4108UW5	maltose o-acetyltransferase
GNX18_12030	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GNX18_12055	ENOG4108NEV	two component transcriptional regulator, LytTR family
GNX18_12060	ENOG4108HRK	Histidine kinase
GNX18_12075	ENOG4105CSU	acyl-Coa dehydrogenase
GNX18_12080	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GNX18_12085	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
GNX18_12090	ENOG4105CDU	Replicative dna helicase
GNX18_12095	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GNX18_12105	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GNX18_12110	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GNX18_12145	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GNX18_12160	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GNX18_12180	ENOG4105D9P	serine threonine protein kinase
GNX18_12205	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GNX18_12305	ENOG4105C2C	drug resistance transporter, Bcr CflA
GNX18_12315	ENOG4105CVE	Lytic murein transglycosylase
GNX18_12320	ENOG4108UT2	hemolysin iii
GNX18_12345	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GNX18_12350	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
GNX18_12355	ENOG4105EPW	hflc protein
GNX18_12360	ENOG4107QJR	hflk protein
GNX18_12365	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GNX18_12370	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GNX18_12380	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GNX18_12385	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GNX18_12390	ENOG4105K8N	protein family UPF0079, ATPase
GNX18_12395	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GNX18_12405	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GNX18_12410	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GNX18_12415	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GNX18_12420	ENOG4105KHC	sulfurtransferase
GNX18_12425	ENOG4105DJ4	phosphatidylserine decarboxylase
GNX18_12430	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GNX18_12435	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GNX18_12440	ENOG4107S6Z	Na H antiporter
GNX18_12445	ENOG4105BZ8	glutamate synthase
GNX18_12450	ENOG4105CBC	glutamate synthase
GNX18_12455	ENOG4105D49	3-dehydroquinate synthase
GNX18_12460	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GNX18_12465	ENOG4105E4G	Type IV pilus
GNX18_12490	ENOG4108JQC	penicillin-binding protein 1A
GNX18_12505	ENOG4105C8Q	Methyl-accepting chemotaxis
GNX18_12510	ENOG4108ZGA	chew protein
GNX18_12515	ENOG4105M3Z	response regulator
GNX18_12520	ENOG4108UNF	response regulator
GNX18_12525	ENOG4105D7Z	glutathione synthase
GNX18_12535	ENOG4108UJU	UPF0301 protein
GNX18_12540	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GNX18_12605	ENOG4105EKQ	RNA-directed DNA polymerase
GNX18_12685	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GNX18_12690	ENOG4105VFU	Rna-binding protein
GNX18_12695	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GNX18_12700	ENOG4105K63	Thioredoxin
GNX18_12705	ENOG4105CSA	Coproporphyrinogen iii oxidase
GNX18_12720	ENOG4105DWV	Homoserine O-trans-acetylase
GNX18_12725	ENOG4105DWV	Homoserine O-trans-acetylase
GNX18_12730	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GNX18_12750	ENOG4108VIA	integral membrane protein
GNX18_12755	ENOG4105II7	pyrroline-5-carboxylate reductase
GNX18_12760	ENOG4105DFA	alanine racemase domain protein
GNX18_12765	ENOG4105CZX	twitching motility protein
GNX18_12770	ENOG4105CZX	twitching motility protein
GNX18_12780	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GNX18_12790	ENOG4108NEV	two component transcriptional regulator, LytTR family
GNX18_12800	ENOG4105CH7	arginosuccinase
GNX18_12810	ENOG4105XQ6	frataxin-like protein
GNX18_12820	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GNX18_12825	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GNX18_12840	ENOG4108YZA	Nitrogen regulatory protein pii
GNX18_12865	ENOG4105C0P	Mg chelatase subunit ChlI
GNX18_12870	ENOG4108YYQ	gCN5-related N-acetyltransferase
GNX18_12880	ENOG4105VDT	-acetyltransferase
GNX18_12885	ENOG4108UPT	UPF0178 protein
GNX18_12905	ENOG4105C4R	Atp-dependent dna helicase
GNX18_12910	ENOG4105MPD	Cytochrome
GNX18_12920	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GNX18_12935	ENOG4105CV8	reductase
GNX18_12940	ENOG4105F27	Major Facilitator
GNX18_12945	ENOG4105HEI	LysR family (Transcriptional regulator
GNX18_12950	ENOG4105D06	uba thif-type nad fad binding protein
GNX18_12955	ENOG4108ZAF	Molybdopterin
GNX18_12960	ENOG4105M00	molybdopterin converting factor, subunit 1
GNX18_12965	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GNX18_12970	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GNX18_12975	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GNX18_12990	ENOG4107R3J	Transporter
GNX18_12995	ENOG4105D9P	serine threonine protein kinase
GNX18_13000	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GNX18_13020	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GNX18_13040	ENOG41076YT	nitrate reductase, gamma subunit
GNX18_13045	ENOG4105R3A	Nitrate reductase
GNX18_13050	ENOG4108IUE	nitrate reductase beta subunit
GNX18_13055	ENOG4105CRU	nitrate reductase, alpha subunit
GNX18_13060	ENOG4105BZU	Histidine kinase
GNX18_13085	ENOG4105DSQ	Nitric oxide reductase
GNX18_13090	ENOG4105CFP	Peptidase U32
GNX18_13100	ENOG4105DQQ	Major facilitator superfamily MFS_1
GNX18_13105	ENOG4105WH1	Two component transcriptional regulator luxr family
GNX18_13110	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GNX18_13115	ENOG4105D05	Receptor
GNX18_13135	ENOG4105CAY	ferredoxin--nadp reductase
GNX18_13140	ENOG4108Z40	Transcriptional regulator
GNX18_13195	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
GNX18_13205	ENOG4107S78	Band 7 protein
GNX18_13230	ENOG4105D75	Capsular exopolysaccharide family
GNX18_13235	ENOG4105DAY	polysaccharide export protein
GNX18_13260	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GNX18_13275	ENOG4105E2K	Glycosyl transferase (Group 1
GNX18_13280	ENOG4105E08	Glycoside hydrolase, family 9
GNX18_13300	ENOG4107T8Q	Glycosyl transferase (Group 1
GNX18_13305	ENOG4107QJZ	Glycosyl transferase, family 2
GNX18_13335	ENOG4105DP0	ferredoxin-NADP reductase
GNX18_13350	ENOG4105C6F	GntR Family Transcriptional Regulator
GNX18_13365	ENOG4105EY3	heparinase II III family protein
GNX18_13370	ENOG4105M5J	Cupin 2, conserved barrel domain protein
GNX18_13375	ENOG4105DPW	Major facilitator superfamily MFS_1
GNX18_13380	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GNX18_13385	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GNX18_13400	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GNX18_13435	ENOG4108Z33	Thiol disulfide Interchange Protein
GNX18_13440	ENOG4106RE7	Cytochrome
GNX18_13445	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GNX18_13460	ENOG4105C2M	dna polymerase I
GNX18_13475	ENOG4105FDK	ABC transporter
GNX18_13480	ENOG4105FAV	ABC, transporter
GNX18_13495	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GNX18_13500	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
GNX18_13520	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
GNX18_13525	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
GNX18_13530	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GNX18_13535	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
GNX18_13540	ENOG4107R73	Mate efflux family protein
GNX18_13560	ENOG4105DGW	oligopeptidase A
GNX18_13565	ENOG4108Z0R	Transferase
GNX18_13580	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
GNX18_13585	ENOG4105CEU	Arginine dihydrolase
GNX18_13610	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GNX18_13625	ENOG4105E2X	shikimate dehydrogenase
GNX18_13635	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GNX18_13640	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GNX18_13645	ENOG4105DKB	L-sorbosone dehydrogenase
GNX18_13650	ENOG4105C79	DNA protecting protein DprA
GNX18_13655	ENOG4108WZM	domain protein
GNX18_13660	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GNX18_13665	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GNX18_13670	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GNX18_13675	ENOG4105C1A	potassium transporter peripheral membrane
GNX18_13680	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GNX18_13690	ENOG4105E54	alpha-amylase
GNX18_13700	ENOG4105C19	ABC transporter
GNX18_13705	ENOG4107RBB	ABC transporter, permease
GNX18_13710	ENOG4107RBB	ABC transporter, permease
GNX18_13740	ENOG4105D1S	lipid A biosynthesis
GNX18_13745	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GNX18_13750	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GNX18_13755	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GNX18_13760	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
GNX18_13765	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GNX18_13770	ENOG4105DR4	Methyltransferase
GNX18_13785	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GNX18_13790	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GNX18_13795	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GNX18_13800	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GNX18_13805	ENOG4105VG0	50S ribosomal protein l34
GNX18_13810	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GNX18_13815	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GNX18_13820	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GNX18_13825	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GNX18_13830	ENOG4105DJ2	Major Facilitator Superfamily
GNX18_13835	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GNX18_13840	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GNX18_13845	ENOG4107QJE	Chromosome Partitioning Protein
GNX18_13850	ENOG4105FA0	parb-like partition protein
GNX18_13860	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GNX18_13865	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GNX18_13870	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GNX18_13880	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GNX18_13885	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GNX18_13890	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GNX18_13895	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GNX18_13900	ENOG4105D78	K07001 NTE family protein
GNX18_13910	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GNX18_13920	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GNX18_13925	ENOG4107RUY	(E1 component), alpha subunit
GNX18_13940	ENOG410804X	Transcriptional regulator
GNX18_13945	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GNX18_13975	ENOG4107RBR	Receptor
GNX18_13980	ENOG4105QNF	Outer membrane lipoprotein
GNX18_13985	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GNX18_13990	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GNX18_14030	ENOG4107RDJ	Sulfotransferase
GNX18_14035	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GNX18_14040	ENOG4105EEQ	Na H antiporter
GNX18_14045	ENOG4105EUB	pirin domain protein
GNX18_14050	ENOG4105C5Q	Transcriptional regulator
GNX18_14060	ENOG4108VBZ	doxx family
GNX18_14065	ENOG4105CHF	Glutathione S-transferase
GNX18_14070	ENOG4108K3A	Glutathione S-transferase
GNX18_14075	ENOG4105C2C	drug resistance transporter, Bcr CflA
GNX18_14080	ENOG4108MAJ	Membrane
GNX18_14085	ENOG4106KNT	transcriptional regulator
GNX18_14090	ENOG4105C4R	Atp-dependent dna helicase
GNX18_14095	ENOG4105CH5	extracellular solute-binding protein, family 7
GNX18_14105	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GNX18_14110	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GNX18_14115	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GNX18_14130	ENOG4105NAU	thioesterase Superfamily protein
GNX18_14135	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GNX18_14150	ENOG4105C8U	phosphate abc transporter
GNX18_14160	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GNX18_14165	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GNX18_14190	ENOG4105D1Q	UPF0246 protein
GNX18_14210	ENOG4105BZU	Histidine kinase
GNX18_14215	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GNX18_14220	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GNX18_14225	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GNX18_14230	ENOG4105CK2	sodium dicarboxylate symporter
GNX18_14245	ENOG4105CB5	ATP-dependent DNA helicase recG
GNX18_14250	ENOG4105C5Q	Transcriptional regulator
GNX18_14255	ENOG4105Y3U	Transglycosylase-associated protein
GNX18_14265	ENOG4105KME	endoribonuclease L-psp
GNX18_14270	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GNX18_14275	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GNX18_14280	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GNX18_14290	ENOG4105DQ4	alcohol dehydrogenase
GNX18_14295	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GNX18_14310	ENOG4105DSJ	YicC domain protein
GNX18_14315	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GNX18_14325	ENOG4105CGK	Exodeoxyribonuclease III
GNX18_14330	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GNX18_14340	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GNX18_14345	ENOG4105CAS	nag kinase
GNX18_14350	ENOG4107QKV	phosphomannomutase
GNX18_14355	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GNX18_14360	ENOG4105W5Q	DNA repair protein (RadC
GNX18_14365	ENOG4105KDC	50s ribosomal protein l28
GNX18_14370	ENOG4105W0E	50S ribosomal protein L33
GNX18_14375	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GNX18_14380	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GNX18_14385	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GNX18_14390	ENOG4106H78	methyltransferase
GNX18_14395	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GNX18_14400	ENOG4105CAK	Cell division ATP-binding protein ftsE
GNX18_14405	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GNX18_14410	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GNX18_14415	ENOG4105M08	Membrane
GNX18_14420	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GNX18_14435	ENOG4105C5H	ABC transporter
GNX18_14450	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GNX18_14455	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
GNX18_14460	ENOG41067MG	lrgb family
GNX18_14470	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GNX18_14475	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
GNX18_14480	ENOG4105D9M	gamma-glutamylcysteine synthetase
GNX18_14490	ENOG4105C6K	Malic enzyme
GNX18_14500	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GNX18_14505	ENOG4105C25	Primosomal protein n'
GNX18_14520	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GNX18_14525	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GNX18_14555	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GNX18_14565	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GNX18_14570	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GNX18_14575	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
GNX18_14580	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GNX18_14585	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GNX18_14605	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GNX18_14615	ENOG4105D64	Mechanosensitive ion channel
GNX18_14625	ENOG4107R1I	NAD-dependent malic enzyme
GNX18_14635	ENOG4105BZU	Histidine kinase
GNX18_14640	ENOG4108UVJ	appr-1-p processing domain protein
GNX18_14680	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GNX18_14685	ENOG4105CHH	sulfate transporter
GNX18_14695	ENOG4105CI3	gtp-binding protein typa
GNX18_14705	ENOG4105NXH	GreA GreB family elongation factor
GNX18_14710	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GNX18_14715	ENOG4105C5F	glutamine synthetase
GNX18_14725	ENOG4105CUX	Signal transduction histidine kinase
GNX18_14730	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GNX18_14740	ENOG4105KU2	hydrolase family 5
GNX18_14745	ENOG4105F4G	Membrane
GNX18_14760	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GNX18_14765	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GNX18_14775	ENOG4105C0H	protease
GNX18_14780	ENOG4105VEJ	Heat shock protein
GNX18_14785	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
GNX18_14800	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GNX18_14825	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GNX18_14980	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GNX18_14995	ENOG4105D6S	protein involved in catabolism of external DNA
GNX18_15030	ENOG4105DZR	Type I site-specific deoxyribonuclease
GNX18_15040	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
GNX18_15055	ENOG4105F5P	DNA-damage-inducible protein d
GNX18_15070	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GNX18_15075	ENOG4105CEN	a g-specific adenine glycosylase
GNX18_15120	ENOG4105UGU	tonB-dependent Receptor
GNX18_15130	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GNX18_15135	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GNX18_15140	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GNX18_15145	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GNX18_15155	ENOG4105CN1	protease
GNX18_15170	ENOG4105CPQ	Dehydrogenase
GNX18_15175	ENOG4108V8F	Transcriptional regulator, MarR family
GNX18_15180	ENOG41063SB	peptidase
GNX18_15185	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GNX18_15190	ENOG4107YZP	Rhodanese domain protein
GNX18_15195	ENOG4105VW4	glutaredoxin 3
GNX18_15200	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GNX18_15235	ENOG4107ZSV	Receptor
GNX18_15245	ENOG4105EKN	Major Facilitator
GNX18_15280	ENOG4105EAC	phosphoserine phosphatase
GNX18_15295	ENOG41066DG	(EAL) domain protein
GNX18_15300	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GNX18_15305	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GNX18_15310	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GNX18_15320	ENOG4105D7W	serine acetyltransferase
GNX18_15325	ENOG4105E27	serine threonine protein kinase
GNX18_15345	ENOG4105MJ2	Competence protein
GNX18_15350	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GNX18_15355	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GNX18_15360	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GNX18_15365	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
GNX18_15370	ENOG4105T0Z	Conserved Protein
GNX18_15395	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GNX18_15405	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GNX18_15410	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GNX18_15415	ENOG4105CYC	Transferase
GNX18_15420	ENOG4105DGU	Histone deacetylase
GNX18_15425	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GNX18_15460	ENOG4105BZU	Histidine kinase
GNX18_15475	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
GNX18_15485	ENOG4108UKI	Enoyl-CoA hydratase
GNX18_15490	ENOG4107QX3	carboxylase
GNX18_15495	ENOG4105C1G	acyl-Coa dehydrogenase
GNX18_15500	ENOG4108Z6Z	Transcriptional regulator
GNX18_15505	ENOG4105JQN	Transcriptional regulator
GNX18_15535	ENOG4105DEF	Extracellular solute-binding protein, family 5
GNX18_15540	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GNX18_15545	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GNX18_15550	ENOG4105C3U	ABC transporter
GNX18_15555	ENOG4108JQ7	(ABC) transporter
GNX18_15575	ENOG4105C84	Histidine ammonia-lyase
GNX18_15580	ENOG4105CGP	Urocanate hydratase
GNX18_15585	ENOG4105CZE	histidine utilization repressor
GNX18_15590	ENOG4105CI2	imidazolone-5-propionate hydrolase
GNX18_15595	ENOG41088SP	formiminoglutamate hydrolase
GNX18_15605	ENOG41066YJ	Beta-lactamase
GNX18_15615	ENOG4108TSE	Transferase
GNX18_15635	ENOG4105C0A	alcohol dehydrogenase
GNX18_15665	ENOG4105N14	lysine exporter protein LysE YggA
GNX18_15675	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GNX18_15680	ENOG4105D3G	Pseudouridine synthase
GNX18_15690	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GNX18_15695	ENOG4105K56	Transcriptional regulator
GNX18_15700	ENOG4105BZM	domain protein
GNX18_15715	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GNX18_15725	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
GNX18_15730	ENOG4105CDV	Ompa motb domain protein
GNX18_15735	ENOG4105EPD	Oligopeptide transporter, Opt family
GNX18_15740	ENOG4105SYT	Methylenetetrahydrofolate reductase
GNX18_15745	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GNX18_15750	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GNX18_15755	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
GNX18_15765	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GNX18_15795	ENOG4105CNM	Receptor
GNX18_15835	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GNX18_15840	ENOG4105HF0	Membrane
GNX18_15870	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GNX18_15875	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GNX18_15880	ENOG4105CCU	oxidase (Subunit III)
GNX18_15885	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GNX18_15890	ENOG4105E2S	oxidase) subunit II
GNX18_15920	ENOG4105BZA	Phosphoglycerate kinase
GNX18_15925	ENOG4105D2N	Aldolase
GNX18_15935	ENOG4105FR1	rard protein
GNX18_15940	ENOG4108JQ1	Dehydrogenase
GNX18_15945	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GNX18_15975	ENOG4105C26	Dehydrogenase
GNX18_15995	ENOG4105EE5	Membrane protein terC
GNX18_16000	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GNX18_16045	ENOG4105C26	Dehydrogenase
GNX18_16050	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GNX18_16055	ENOG4105EVZ	LysR family transcriptional regulator
GNX18_16085	ENOG4105CVK	Glutamate decarboxylase
GNX18_16100	ENOG4105C5H	ABC transporter
GNX18_16110	ENOG4105VEQ	Cold shock protein
GNX18_16115	ENOG4105BZ1	(ABC) transporter
GNX18_16130	ENOG4105C5H	ABC transporter
GNX18_16145	ENOG4108K3A	Glutathione S-transferase
GNX18_16160	ENOG4105C1J	atp-dependent rna helicase
GNX18_16170	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GNX18_16180	ENOG4108RXX	maleylacetoacetate isomerase
GNX18_16215	ENOG4105KWG	Pfam:DUF1696
GNX18_16240	ENOG4107R6D	beta-lactam binding protein AmpH
GNX18_16290	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GNX18_16300	ENOG4105C1G	acyl-Coa dehydrogenase
GNX18_16305	ENOG4108ZG0	Ompa motb domain protein
GNX18_16330	ENOG4105E66	phosphoriboisomerase A
GNX18_16335	ENOG4105C7B	Threonine dehydratase
GNX18_16340	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GNX18_16350	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GNX18_16365	ENOG4107RAQ	aminopeptidase
GNX18_16370	ENOG4105D0A	hydroxylase
GNX18_16375	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GNX18_16380	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
GNX18_16425	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GNX18_16430	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GNX18_16435	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GNX18_16440	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GNX18_16455	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GNX18_16460	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GNX18_16465	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GNX18_16480	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GNX18_16485	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GNX18_16510	ENOG4109015	Biopolymer transport protein exbD tolR
GNX18_16515	ENOG41067XB	TonB family
GNX18_16525	ENOG41067XB	TonB family
GNX18_16530	ENOG4105C01	Dihydroxy-acid dehydratase
GNX18_16535	ENOG4107QZM	n-acetylglutamate synthase
GNX18_16540	ENOG4105CWC	Acetylornithine deacetylase
GNX18_16545	ENOG4105EMK	carboxylate amino acid amine transporter
GNX18_16555	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GNX18_16560	ENOG4105CJ3	phosphate transporter
GNX18_16565	ENOG4107IX6	phosphate transport regulator
GNX18_16570	ENOG4107QHF	type ii secretion system protein e
GNX18_16590	ENOG4105CIG	ABC transporter
GNX18_16595	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GNX18_16600	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GNX18_16615	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GNX18_16635	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GNX18_16645	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GNX18_16655	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GNX18_16685	ENOG4105DFG	type I secretion outer membrane protein
GNX18_16690	ENOG4105H2K	paraquat-inducible protein a
GNX18_16695	ENOG4105F1S	paraquat-inducible protein a
GNX18_16700	ENOG4105DY2	Paraquat-inducible protein b
GNX18_16715	ENOG41087AY	ADP-Ribose pyrophosphatase
GNX18_16720	ENOG4108SX3	cytoplasmic protein
GNX18_16725	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GNX18_16735	ENOG4105IPS	esterase
GNX18_16740	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GNX18_16780	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GNX18_16795	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GNX18_16815	ENOG4105CT4	transporter
GNX18_16820	ENOG4105C01	Dihydroxy-acid dehydratase
GNX18_16825	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
GNX18_16830	ENOG4105R0I	Feruloyl esterase
GNX18_16860	ENOG4105R0I	Feruloyl esterase
GNX18_16880	ENOG4105CSU	acyl-Coa dehydrogenase
GNX18_16885	ENOG4108UHU	Aldolase
GNX18_16890	ENOG4105DMF	Dehydrogenase
GNX18_16905	ENOG4105C9F	isomerase
GNX18_16960	ENOG4105C09	Bile acid
GNX18_16965	ENOG4105C1J	atp-dependent rna helicase
GNX18_16980	ENOG4105CFC	Transporter
GNX18_16985	ENOG4105EIF	outer membrane protein W
GNX18_16995	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GNX18_17000	ENOG4108YZ9	Urea amidohydrolase subunit gamma
GNX18_17005	ENOG4105KI2	Urea amidohydrolase subunit beta
GNX18_17010	ENOG4105CQM	Urea amidohydrolase subunit alpha
GNX18_17015	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
GNX18_17020	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GNX18_17025	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
GNX18_17040	ENOG4105EA8	2-Nitropropane dioxygenase
GNX18_17050	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GNX18_17055	ENOG4105BZU	Histidine kinase
GNX18_17070	ENOG4105C32	Amino acid ABC transporter (Permease)
GNX18_17080	ENOG4105C0Z	ABC transporter
GNX18_17085	ENOG4108IV0	ABC, transporter
GNX18_17100	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
GNX18_17105	ENOG4105CT4	transporter
GNX18_17110	ENOG4105EMF	GntR family transcriptional regulator
GNX18_17140	ENOG4105EQD	regulatoR
GNX18_17155	ENOG4107T94	Endo-14-beta-xylanase
GNX18_17185	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GNX18_17190	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
GNX18_17195	ENOG4105C2J	ABC transporter
GNX18_17200	ENOG4107R9N	ABC transporter
GNX18_17205	ENOG41062B0	ABC transporter, permease
GNX18_17215	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
GNX18_17225	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
GNX18_17230	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
GNX18_17240	ENOG4105CGS	Alpha-glucosidase
GNX18_17250	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
GNX18_17265	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
GNX18_17270	ENOG4105BZU	Histidine kinase
GNX18_17275	ENOG4108ZJ4	polysaccharide deacetylase
GNX18_17285	ENOG4106Z5D	Glycoside Hydrolase Family 43
GNX18_17295	ENOG4105C5H	ABC transporter
GNX18_17300	ENOG4105E39	Enoyl-CoA hydratase
GNX18_17305	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GNX18_17310	ENOG4105D4P	Coproporphyrinogen iii oxidase
GNX18_17315	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GNX18_17330	ENOG41090JE	Utilization Protein
GNX18_17345	ENOG41090AP	transport protein
GNX18_17350	ENOG4106GFD	transport protein
GNX18_17360	ENOG4105EHG	Permease protein
GNX18_17365	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GNX18_17370	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GNX18_17375	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GNX18_17380	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GNX18_17390	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GNX18_17395	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GNX18_17400	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GNX18_17405	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GNX18_17410	ENOG4108ZAI	phosphatidylglycerophosphatase a
GNX18_17420	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GNX18_17425	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GNX18_17435	ENOG4105E0F	Histidine kinase
GNX18_17440	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GNX18_17455	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GNX18_17460	ENOG4105CTB	Polyprenyl synthetase
GNX18_17470	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GNX18_17485	ENOG4108UYB	regulatoR
GNX18_17500	ENOG4105CPF	Cell wall formation (By similarity)
GNX18_17530	ENOG4105CEP	NADH dehydrogenase
GNX18_17540	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GNX18_17560	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GNX18_17580	ENOG4105EKQ	RNA-directed DNA polymerase
GNX18_17630	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GNX18_17665	ENOG4105CPC	Aldo Keto reductase
GNX18_17670	ENOG4105EJC	lysr family transcriptional regulator
GNX18_17680	ENOG4105E2Y	ABC, transporter
GNX18_17690	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GNX18_17700	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GNX18_17710	ENOG4105E08	Glycoside hydrolase, family 9
GNX18_17730	ENOG4105CW7	secretion protein, HlyD family
GNX18_17735	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GNX18_17750	ENOG4105DSG	hydrolase family 43
GNX18_17755	ENOG4105CT4	transporter
GNX18_17765	ENOG4105CNG	UPF0061 protein
GNX18_17770	ENOG4105C9X	ppx gppa phosphatase
GNX18_17790	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
GNX18_17795	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GNX18_17800	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GNX18_17805	ENOG41079KZ	Major Facilitator Superfamily
GNX18_17815	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
GNX18_17820	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
GNX18_17840	ENOG4107RGM	aldo keto reductase
GNX18_17850	ENOG4107WD4	Releases the N-terminal proline from various substrates (By similarity)
GNX18_17855	ENOG4105CJ1	ABC, transporter
GNX18_17860	ENOG4108SDH	ABC, transporter
GNX18_17865	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GNX18_17870	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GNX18_17875	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
GNX18_17905	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GNX18_17915	ENOG4105PM1	preprotein translocase subunit SecE
GNX18_17920	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GNX18_17925	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GNX18_17930	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GNX18_17940	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GNX18_17945	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GNX18_17950	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GNX18_17960	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GNX18_17965	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GNX18_17970	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GNX18_17980	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GNX18_17985	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GNX18_17990	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GNX18_17995	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GNX18_18000	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GNX18_18005	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GNX18_18010	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GNX18_18015	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GNX18_18020	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GNX18_18025	ENOG41083MP	50s ribosomal protein l29
GNX18_18030	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GNX18_18035	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GNX18_18040	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GNX18_18045	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GNX18_18050	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GNX18_18055	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GNX18_18060	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GNX18_18065	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GNX18_18070	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GNX18_18075	ENOG4105VPB	50S ribosomal protein L30
GNX18_18080	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GNX18_18085	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GNX18_18090	ENOG41067V7	50S ribosomal protein L36
GNX18_18095	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GNX18_18100	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GNX18_18105	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GNX18_18110	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GNX18_18115	ENOG4108ZT0	50S ribosomal protein l17
GNX18_18120	ENOG4105VUT	cytoplasmic protein
GNX18_18130	ENOG4105P4J	Allophanate hydrolase, subunit 1
GNX18_18135	ENOG4105E7W	lamb ycsf family protein
GNX18_18140	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GNX18_18150	ENOG4107RDB	Major Facilitator
GNX18_18155	ENOG4108UUM	single-stranded DNA-binding protein
GNX18_18170	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GNX18_18175	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GNX18_18185	ENOG4105EAH	synthase
GNX18_18190	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GNX18_18195	ENOG4105K46	50S ribosomal protein l27
GNX18_18200	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GNX18_18205	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GNX18_18210	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GNX18_18215	ENOG4105BZU	Histidine kinase
GNX18_18220	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GNX18_18225	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GNX18_18235	ENOG4105CJR	Integral membrane protein (MviN
GNX18_18240	ENOG4105DTN	riboflavin biosynthesis protein ribF
GNX18_18245	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GNX18_18250	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GNX18_18255	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GNX18_18260	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GNX18_18285	ENOG4105CWU	Biogenesis protein
GNX18_18300	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GNX18_18305	ENOG4107TUY	Histidine kinase
GNX18_18310	ENOG4105C4K	Nad synthetase
GNX18_18315	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GNX18_18320	ENOG4105C34	Pseudouridine synthase
GNX18_18325	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GNX18_18330	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GNX18_18335	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GNX18_18340	ENOG4105BZS	acriflavin resistance protein
GNX18_18350	ENOG4105C7K	acetolactate synthase
GNX18_18355	ENOG4108ZP8	Acetolactate synthase small subunit
GNX18_18360	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GNX18_18365	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
GNX18_18415	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GNX18_18425	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GNX18_18445	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GNX18_18470	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
GNX18_18475	ENOG4105C9K	Endothelin-converting enzyme 1
GNX18_18490	ENOG4105IJJ	transcriptional regulator, crp fnr family
GNX18_18520	ENOG4108Z5K	methylglyoxal synthase
GNX18_18525	ENOG4109015	Biopolymer transport protein exbD tolR
GNX18_18530	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
GNX18_18535	ENOG4105CGU	Enoyl-CoA hydratase
GNX18_18540	ENOG4105BZU	Histidine kinase
GNX18_18585	ENOG4105E6M	Sulphatase-modifying factor protein
GNX18_18620	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GNX18_18625	ENOG41069YE	inner membrane protein yohC
GNX18_18645	ENOG4105DZB	Electron transport complex
GNX18_18650	ENOG4108UQQ	Electron transport complex
GNX18_18655	ENOG4105D6A	Electron transport complex
GNX18_18665	ENOG4108R3D	Electron transport complex
GNX18_18670	ENOG4105DGN	Electron transport complex
GNX18_18700	ENOG4105I4A	GCN5-related N-acetyltransferase
GNX18_18710	ENOG4105CC0	LysR family Transcriptional regulator
GNX18_18715	ENOG4105CYM	Glutathione S-transferase
GNX18_18720	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GNX18_18725	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
GNX18_18730	ENOG4105D9P	serine threonine protein kinase
GNX18_18735	ENOG4105TMB	Formate nitrite transporter
GNX18_18765	ENOG4105C5I	Dehydrogenase
GNX18_18770	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GNX18_18775	ENOG4105D1F	ATP-binding protein
GNX18_18790	ENOG4105C72	UPF0176 protein
GNX18_18820	ENOG4105CQB	FAD linked oxidase domain protein
GNX18_18830	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GNX18_18845	ENOG4105CHM	Aminotransferase
GNX18_18850	ENOG4108RYR	transcriptional regulator AsnC family
GNX18_18870	ENOG4105E4C	Lytic transglycosylase catalytic
GNX18_18875	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GNX18_18880	ENOG4105K70	DNA-binding protein
GNX18_18890	ENOG4105C9M	aspartyl-trna synthetase
GNX18_18900	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GNX18_18905	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GNX18_18910	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GNX18_18915	ENOG4107YD3	Thioesterase
GNX18_18920	ENOG4105E02	MotA TolQ exbB proton channel
GNX18_18925	ENOG4105M8F	Biopolymer transport protein exbD tolR
GNX18_18935	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GNX18_18940	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GNX18_18950	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GNX18_18955	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GNX18_18970	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GNX18_18975	ENOG4105ERG	peptidase m48, ste24p
GNX18_18980	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GNX18_18990	ENOG4105C8V	SAICAR synthetase
GNX18_19005	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GNX18_19010	ENOG4107QSN	dihydrolipoamide acetyltransferase
GNX18_19070	ENOG4105WH1	Two component transcriptional regulator luxr family
GNX18_19085	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GNX18_19095	ENOG4105CUX	Signal transduction histidine kinase
GNX18_19100	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GNX18_19105	ENOG4107RBB	ABC transporter, permease
GNX18_19115	ENOG4105C19	ABC transporter
GNX18_19125	ENOG4105CHH	sulfate transporter
GNX18_19140	ENOG4105RKW	reductase (By
GNX18_19145	ENOG4105CPC	Aldo Keto reductase
GNX18_19155	ENOG4105D1S	lipid A biosynthesis
GNX18_19160	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GNX18_19170	ENOG4105Q2H	domain protein
GNX18_19175	ENOG4105DSB	aldose 1-epimerase
GNX18_19190	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GNX18_19200	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GNX18_19205	ENOG4105DJ0	Poly(A) Polymerase
GNX18_19215	ENOG4105BZU	Histidine kinase
GNX18_19220	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GNX18_19230	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GNX18_19240	ENOG4105C0H	protease
GNX18_19245	ENOG4105D0M	Protease HtpX homolog
GNX18_19260	ENOG4105D7W	serine acetyltransferase
GNX18_19295	ENOG4105F0N	pyrophosphate phospho-hydrolase
GNX18_19320	ENOG4107ZSV	Receptor
GNX18_19340	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GNX18_19350	ENOG4107ZSV	Receptor