locus-tag	class	description
FOE78_00015	COG0745	RESPONSE REGULATOR receiver
FOE78_00020	COG2205	protein histidine kinase activity
FOE78_00060	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOE78_00060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOE78_00065	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOE78_00075	COG2197	response regulator
FOE78_00080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOE78_00080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOE78_00095	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOE78_00110	COG1174	glycine betaine transport
FOE78_00125	COG0738	Major facilitator superfamily
FOE78_00140	COG2181	nitrate reductase activity
FOE78_00140	COG0247	lactate metabolic process
FOE78_00160	COG0717	Belongs to the dCTP deaminase family
FOE78_00200	COG4585	Histidine kinase
FOE78_00205	COG2197	response regulator
FOE78_00235	COG1201	RNA secondary structure unwinding
FOE78_00270	COG1902	pentaerythritol trinitrate reductase activity
FOE78_00270	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOE78_00275	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_00280	COG1960	acyl-CoA dehydrogenase activity
FOE78_00285	COG0318	PFAM AMP-dependent synthetase and ligase
FOE78_00310	COG2205	protein histidine kinase activity
FOE78_00335	COG3483	tryptophan 2,3-dioxygenase activity
FOE78_00350	COG3428	Bacterial PH domain
FOE78_00355	COG1940	carbohydrate kinase activity
FOE78_00360	COG0018	arginyl-trna synthetase
FOE78_00370	COG4941	Belongs to the sigma-70 factor family
FOE78_00385	COG2146	nitrite reductase [NAD(P)H] activity
FOE78_00385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOE78_00390	COG2223	nitrite transmembrane transporter activity
FOE78_00395	COG0243	molybdopterin cofactor binding
FOE78_00410	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOE78_00425	COG0166	Belongs to the GPI family
FOE78_00445	COG2094	Belongs to the DNA glycosylase MPG family
FOE78_00460	COG0673	inositol 2-dehydrogenase activity
FOE78_00465	COG2720	vancomycin resistance protein
FOE78_00520	COG2244	polysaccharide biosynthetic process
FOE78_00525	COG1215	transferase activity, transferring glycosyl groups
FOE78_00575	COG5285	phytanoyl-CoA dioxygenase
FOE78_00585	COG4209	transmembrane transport
FOE78_00590	COG0395	ABC-type sugar transport system, permease component
FOE78_00605	COG0653	protein targeting
FOE78_00610	COG1960	acyl-CoA dehydrogenase activity
FOE78_00625	COG0477	Major facilitator Superfamily
FOE78_00630	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOE78_00635	COG0022	dehydrogenase e1 component
FOE78_00660	COG2378	regulation of single-species biofilm formation
FOE78_00680	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_00690	COG1609	Transcriptional regulator
FOE78_00695	COG0395	ABC-type sugar transport system, permease component
FOE78_00700	COG1175	transmembrane transport
FOE78_00710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOE78_00710	COG1648	precorrin-2 dehydrogenase activity
FOE78_00755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_00760	COG0601	transmembrane transport
FOE78_00775	COG1132	(ABC) transporter
FOE78_00780	COG1132	(ABC) transporter
FOE78_00795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOE78_00805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOE78_00810	COG0667	Aldo Keto reductase
FOE78_00815	COG1950	PFAM Membrane protein of
FOE78_00820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOE78_00840	COG2409	Drug exporters of the RND superfamily
FOE78_00850	COG0745	RESPONSE REGULATOR receiver
FOE78_00855	COG2205	protein histidine kinase activity
FOE78_00870	COG0513	Belongs to the DEAD box helicase family
FOE78_00875	COG3022	response to hydroperoxide
FOE78_00910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOE78_00920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOE78_00960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOE78_00990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOE78_01005	COG1271	oxidase subunit
FOE78_01010	COG1294	oxidase, subunit
FOE78_01015	COG4988	ABC transporter
FOE78_01020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOE78_01035	COG0024	Methionine aminopeptidase
FOE78_01040	COG1063	alcohol dehydrogenase
FOE78_01050	COG3409	Peptidoglycan-binding domain 1 protein
FOE78_01050	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOE78_01080	COG4978	Transcriptional regulator
FOE78_01080	COG0789	Transcriptional regulator
FOE78_01100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOE78_01110	COG1119	ATPase activity
FOE78_01120	COG3250	beta-galactosidase activity
FOE78_01155	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FOE78_01165	COG1372	Participates in initiation and elongation during chromosome replication
FOE78_01165	COG0305	Participates in initiation and elongation during chromosome replication
FOE78_01170	COG1937	Protein conserved in bacteria
FOE78_01175	COG2608	mercury ion transmembrane transporter activity
FOE78_01180	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOE78_01255	COG1309	transcriptional regulator
FOE78_01285	COG0596	Alpha beta hydrolase
FOE78_01315	COG0617	tRNA 3'-terminal CCA addition
FOE78_01340	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOE78_01350	COG3118	belongs to the thioredoxin family
FOE78_01360	COG4948	Mandelate Racemase Muconate Lactonizing
FOE78_01365	COG0246	Mannitol dehydrogenase
FOE78_01390	COG2814	Major facilitator Superfamily
FOE78_01400	COG1192	Involved in chromosome partitioning
FOE78_01405	COG1484	DNA-dependent DNA replication
FOE78_01415	COG0357	Ribosomal RNA small subunit methyltransferase G
FOE78_01425	COG0706	membrane insertase activity
FOE78_01435	COG0594	ribonuclease P activity
FOE78_01440	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOE78_01445	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOE78_01450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOE78_01455	COG1174	glycine betaine transport
FOE78_01460	COG0517	IMP dehydrogenase activity
FOE78_01460	COG1125	glycine betaine transport
FOE78_01465	COG1174	glycine betaine transport
FOE78_01470	COG1732	Glycine betaine
FOE78_01475	COG0592	DNA-directed DNA polymerase activity
FOE78_01480	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOE78_01485	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOE78_01490	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FOE78_01520	COG0387	Pfam Sodium calcium exchanger
FOE78_01525	COG3119	arylsulfatase activity
FOE78_01530	COG0187	DNA topoisomerase II activity
FOE78_01535	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOE78_01545	COG3328	transposase activity
FOE78_01555	COG4962	Type ii secretion system protein e
FOE78_01580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOE78_01595	COG0577	efflux transmembrane transporter activity
FOE78_01595	COG1136	(ABC) transporter
FOE78_01600	COG2197	response regulator
FOE78_01605	COG4585	Histidine kinase
FOE78_01610	COG2807	transmembrane transport
FOE78_01630	COG1957	nucleoside hydrolase
FOE78_01660	COG0494	nUDIX hydrolase
FOE78_01670	COG2801	Transposase and inactivated derivatives
FOE78_01700	COG1674	ftsk spoiiie
FOE78_01745	COG1196	nuclear chromosome segregation
FOE78_01745	COG0741	lytic transglycosylase activity
FOE78_01745	COG0739	heme binding
FOE78_01770	COG3220	belongs to the UPF0276 family
FOE78_01780	COG0438	transferase activity, transferring glycosyl groups
FOE78_01825	COG0582	viral genome integration into host DNA
FOE78_01845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOE78_01875	COG1940	carbohydrate kinase activity
FOE78_01900	COG4941	Belongs to the sigma-70 factor family
FOE78_01960	COG0277	FAD linked oxidase domain protein
FOE78_01975	COG0300	oxidoreductase activity
FOE78_01980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOE78_01985	COG0569	domain protein
FOE78_02005	COG0501	Belongs to the peptidase M48B family
FOE78_02015	COG2318	DinB family
FOE78_02030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOE78_02035	COG0360	Binds together with S18 to 16S ribosomal RNA
FOE78_02040	COG0629	single-stranded DNA binding
FOE78_02045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOE78_02050	COG0359	binds to the 23S rRNA
FOE78_02055	COG0069	glutamate synthase activity
FOE78_02065	COG1609	Transcriptional regulator
FOE78_02085	COG1175	transmembrane transport
FOE78_02110	COG4942	peptidase
FOE78_02130	COG0252	asparaginase activity
FOE78_02150	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOE78_02155	COG0732	type I restriction modification DNA specificity domain
FOE78_02165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOE78_02180	COG3328	transposase activity
FOE78_02190	COG1484	DNA-dependent DNA replication
FOE78_02200	COG2801	Transposase and inactivated derivatives
FOE78_02225	COG0494	nUDIX hydrolase
FOE78_02235	COG1487	ribonuclease activity
FOE78_02260	COG1595	DNA-templated transcription, initiation
FOE78_02275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOE78_02300	COG0395	ABC-type sugar transport system, permease component
FOE78_02305	COG1653	transport
FOE78_02325	COG1063	alcohol dehydrogenase
FOE78_02330	COG3903	Transcriptional regulator
FOE78_02330	COG2197	response regulator
FOE78_02340	COG2132	Multicopper oxidase
FOE78_02355	COG1131	(ABC) transporter
FOE78_02360	COG3559	Exporter of polyketide antibiotics
FOE78_02365	COG0534	Mate efflux family protein
FOE78_02375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOE78_02385	COG0183	Belongs to the thiolase family
FOE78_02390	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOE78_02425	COG0515	serine threonine protein kinase
FOE78_02430	COG0768	penicillin binding
FOE78_02445	COG1716	ATPase activity
FOE78_02450	COG1716	ATPase activity
FOE78_02450	COG1716	ATPase activity
FOE78_02460	COG1473	amidohydrolase
FOE78_02480	COG2837	iron assimilation
FOE78_02485	COG2822	iron ion transport
FOE78_02490	COG0672	)-iron permease
FOE78_02515	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FOE78_02525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOE78_02540	COG0583	DNA-binding transcription factor activity
FOE78_02545	COG0584	glycerophosphoryl diester phosphodiesterase
FOE78_02560	COG2235	arginine
FOE78_02565	COG1215	transferase activity, transferring glycosyl groups
FOE78_02580	COG1121	(ABC) transporter
FOE78_02595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOE78_02615	COG1597	lipid kinase activity
FOE78_02620	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOE78_02625	COG0561	phosphatase activity
FOE78_02650	COG1132	(ABC) transporter
FOE78_02655	COG0673	inositol 2-dehydrogenase activity
FOE78_02660	COG2130	NADP-dependent
FOE78_02675	COG1316	TRANSCRIPTIONal
FOE78_02700	COG1674	ftsk spoiiie
FOE78_02735	COG0494	nUDIX hydrolase
FOE78_02740	COG0438	transferase activity, transferring glycosyl groups
FOE78_02750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOE78_02765	COG1132	(ABC) transporter
FOE78_02770	COG1132	(ABC) transporter
FOE78_02780	COG2442	InterPro IPR007367
FOE78_02785	COG1309	transcriptional regulator
FOE78_02790	COG3848	Pyruvate phosphate dikinase
FOE78_02790	COG0574	Belongs to the PEP-utilizing enzyme family
FOE78_02795	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FOE78_02830	COG1280	lysine exporter protein (LysE YggA)
FOE78_02830	COG1674	ftsk spoiiie
FOE78_02905	COG0741	lytic transglycosylase activity
FOE78_02905	COG0739	heme binding
FOE78_02905	COG1196	nuclear chromosome segregation
FOE78_02960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOE78_02965	COG1012	belongs to the aldehyde dehydrogenase family
FOE78_02980	COG0667	Aldo Keto reductase
FOE78_02985	COG4221	oxidoreductase activity
FOE78_03010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOE78_03015	COG3119	arylsulfatase activity
FOE78_03020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOE78_03040	COG2814	Major facilitator Superfamily
FOE78_03060	COG0745	RESPONSE REGULATOR receiver
FOE78_03080	COG1960	acyl-CoA dehydrogenase activity
FOE78_03085	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOE78_03090	COG1573	uracil-dna glycosylase
FOE78_03095	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOE78_03115	COG0569	domain protein
FOE78_03115	COG0475	glutathione-regulated potassium exporter activity
FOE78_03125	COG3328	transposase activity
FOE78_03140	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FOE78_03155	COG1136	(ABC) transporter
FOE78_03155	COG0577	efflux transmembrane transporter activity
FOE78_03160	COG1136	(ABC) transporter
FOE78_03165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOE78_03175	COG3263	regulation of cellular component size
FOE78_03235	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOE78_03240	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOE78_03300	COG3386	PFAM SMP-30 Gluconolaconase
FOE78_03315	COG0017	Asparaginyl-tRNA synthetase
FOE78_03325	COG2755	lipolytic protein G-D-S-L family
FOE78_03325	COG0657	acetylesterase activity
FOE78_03415	COG1408	metallophosphoesterase
FOE78_03425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOE78_03435	COG0003	Pfam Anion-transporting ATPase
FOE78_03470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOE78_03485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOE78_03490	COG0494	nUDIX hydrolase
FOE78_03505	COG4152	abc transporter atp-binding protein
FOE78_03510	COG2197	response regulator
FOE78_03520	COG1131	(ABC) transporter
FOE78_03535	COG4585	Histidine kinase
FOE78_03545	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOE78_03555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOE78_03560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOE78_03625	COG1111	helicase
FOE78_03625	COG1205	dead DEAH box helicase
FOE78_03630	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FOE78_03645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOE78_03650	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOE78_03655	COG1120	ATPase activity
FOE78_03670	COG0671	phosphoesterase, PA-phosphatase related
FOE78_03690	COG1309	transcriptional regulator
FOE78_03705	COG2890	protein-(glutamine-N5) methyltransferase activity
FOE78_03710	COG1754	DNA topoisomerase type I activity
FOE78_03710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOE78_03720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOE78_03735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOE78_03740	COG1388	LysM domain
FOE78_03750	COG1774	PSP1 C-terminal conserved region
FOE78_03755	COG0596	Alpha beta hydrolase
FOE78_03760	COG0747	negative chemotaxis
FOE78_03865	COG3250	beta-galactosidase activity
FOE78_03870	COG1072	(Pantothenic acid kinase))
FOE78_03875	COG0640	Transcriptional regulator
FOE78_03885	COG3291	Pkd domain containing protein
FOE78_03940	COG0673	inositol 2-dehydrogenase activity
FOE78_03960	COG0489	protein tyrosine kinase activity
FOE78_03970	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOE78_03980	COG3458	cephalosporin-C deacetylase activity
FOE78_03995	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOE78_04020	COG0037	tRNA processing
FOE78_04030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOE78_04035	COG2318	DinB family
FOE78_04050	COG0302	gtp cyclohydrolase
FOE78_04055	COG3511	phospholipase C
FOE78_04060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOE78_04090	COG0649	NAD binding
FOE78_04100	COG1131	(ABC) transporter
FOE78_04120	COG0542	response to heat
FOE78_04125	COG1228	amidohydrolase
FOE78_04130	COG5006	permease, DMT superfamily
FOE78_04135	COG3938	Belongs to the proline racemase family
FOE78_04170	COG0656	L-ascorbic acid biosynthetic process
FOE78_04210	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOE78_04215	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOE78_04215	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOE78_04220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOE78_04230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOE78_04250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOE78_04255	COG4948	Mandelate Racemase Muconate Lactonizing
FOE78_04260	COG1312	Catalyzes the dehydration of D-mannonate
FOE78_04280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOE78_04285	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOE78_04300	COG2837	iron assimilation
FOE78_04325	COG1136	(ABC) transporter
FOE78_04340	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOE78_04340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOE78_04370	COG3328	transposase activity
FOE78_04380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOE78_04395	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
FOE78_04400	COG2814	Major facilitator Superfamily
FOE78_04405	COG1666	GTP binding
FOE78_04410	COG0456	acetyltransferase
FOE78_04425	COG1609	Transcriptional regulator
FOE78_04440	COG0395	ABC-type sugar transport system, permease component
FOE78_04485	COG2186	Transcriptional regulator
FOE78_04490	COG2271	Major facilitator Superfamily
FOE78_04495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOE78_04495	COG0473	3-isopropylmalate dehydrogenase activity
FOE78_04525	COG1609	Transcriptional regulator
FOE78_04540	COG1175	transmembrane transport
FOE78_04545	COG3833	ABC-type maltose transport systems, permease component
FOE78_04555	COG1312	Catalyzes the dehydration of D-mannonate
FOE78_04560	COG0473	3-isopropylmalate dehydrogenase activity
FOE78_04560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOE78_04565	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_04665	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOE78_04695	COG3328	transposase activity
FOE78_04705	COG1484	DNA-dependent DNA replication
FOE78_04730	COG3328	transposase activity
FOE78_04735	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
FOE78_04805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOE78_04820	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FOE78_04905	COG2801	Transposase and inactivated derivatives
FOE78_05010	COG0739	heme binding
FOE78_05025	COG0673	inositol 2-dehydrogenase activity
FOE78_05040	COG0395	ABC-type sugar transport system, permease component
FOE78_05055	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_05065	COG1024	Enoyl-CoA hydratase
FOE78_05075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOE78_05090	COG1609	Transcriptional regulator
FOE78_05100	COG1175	transmembrane transport
FOE78_05105	COG0395	ABC-type sugar transport system, permease component
FOE78_05125	COG1175	transmembrane transport
FOE78_05130	COG0395	ABC-type sugar transport system, permease component
FOE78_05135	COG2188	Transcriptional regulator
FOE78_05155	COG1940	carbohydrate kinase activity
FOE78_05160	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FOE78_05180	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOE78_05215	COG0582	viral genome integration into host DNA
FOE78_05245	COG1278	Cold shock
FOE78_05250	COG2409	Drug exporters of the RND superfamily
FOE78_05255	COG4585	Histidine kinase
FOE78_05260	COG2197	response regulator
FOE78_05265	COG0477	Major facilitator Superfamily
FOE78_05280	COG3328	transposase activity
FOE78_05290	COG2226	methyltransferase
FOE78_05295	COG0798	PFAM Bile acid sodium symporter
FOE78_05320	COG3158	transport of potassium into the cell
FOE78_05325	COG1846	Transcriptional regulator
FOE78_05405	COG0702	epimerase
FOE78_05420	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FOE78_05430	COG1562	ergosterol biosynthetic process
FOE78_05445	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOE78_05465	COG0009	L-threonylcarbamoyladenylate synthase
FOE78_05490	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
FOE78_05540	COG1132	(ABC) transporter
FOE78_05560	COG1132	(ABC) transporter
FOE78_05565	COG1132	(ABC) transporter
FOE78_05580	COG1940	carbohydrate kinase activity
FOE78_05585	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FOE78_05605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOE78_05610	COG0318	PFAM AMP-dependent synthetase and ligase
FOE78_05615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOE78_05625	COG1063	alcohol dehydrogenase
FOE78_05640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOE78_05650	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_05660	COG2124	cytochrome p450
FOE78_05665	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FOE78_05670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOE78_05685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOE78_05695	COG2030	dehydratase
FOE78_05705	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOE78_05715	COG0318	PFAM AMP-dependent synthetase and ligase
FOE78_05720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOE78_05725	COG2814	Major facilitator Superfamily
FOE78_05735	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOE78_05740	COG0250	Participates in transcription elongation, termination and antitermination
FOE78_05745	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOE78_05750	COG0081	regulation of translation
FOE78_05760	COG0444	Belongs to the ABC transporter superfamily
FOE78_05765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_05770	COG0601	transmembrane transport
FOE78_05785	COG0791	NLP P60 protein
FOE78_05795	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOE78_05800	COG0222	ribosome binding
FOE78_05835	COG0583	DNA-binding transcription factor activity
FOE78_05840	COG0085	RNA polymerase activity
FOE78_05845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOE78_05855	COG2271	Major facilitator Superfamily
FOE78_05870	COG1285	pathogenesis
FOE78_05895	COG1316	TRANSCRIPTIONal
FOE78_05910	COG0667	Aldo Keto reductase
FOE78_05915	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOE78_05920	COG0049	tRNA binding
FOE78_05925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOE78_05930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOE78_05950	COG1120	ATPase activity
FOE78_05955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOE78_05975	COG2801	Transposase and inactivated derivatives
FOE78_05985	COG1131	(ABC) transporter
FOE78_05995	COG4585	Histidine kinase
FOE78_06000	COG2197	response regulator
FOE78_06010	COG0051	transcription antitermination factor activity, RNA binding
FOE78_06015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOE78_06020	COG0088	Forms part of the polypeptide exit tunnel
FOE78_06025	COG0089	rRNA binding
FOE78_06030	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOE78_06035	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOE78_06040	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOE78_06045	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOE78_06050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOE78_06055	COG0255	Belongs to the universal ribosomal protein uL29 family
FOE78_06060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOE78_06065	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOE78_06070	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOE78_06075	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOE78_06080	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOE78_06085	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOE78_06090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOE78_06095	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOE78_06100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOE78_06105	COG1841	ribosomal large subunit assembly
FOE78_06110	COG0200	Binds to the 23S rRNA
FOE78_06120	COG0563	adenylate kinase activity
FOE78_06150	COG1505	serine-type exopeptidase activity
FOE78_06155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOE78_06170	COG3876	Protein conserved in bacteria
FOE78_06185	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOE78_06195	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOE78_06200	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOE78_06205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOE78_06210	COG0202	RNA polymerase activity
FOE78_06215	COG0203	ribosomal protein L17
FOE78_06230	COG0372	Belongs to the citrate synthase family
FOE78_06245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOE78_06250	COG4941	Belongs to the sigma-70 factor family
FOE78_06255	COG3795	YCII-related domain
FOE78_06260	COG4608	Belongs to the ABC transporter superfamily
FOE78_06265	COG0444	Belongs to the ABC transporter superfamily
FOE78_06270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_06275	COG0601	transmembrane transport
FOE78_06285	COG1793	dna ligase
FOE78_06295	COG0477	Major facilitator Superfamily
FOE78_06300	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOE78_06315	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOE78_06320	COG0101	tRNA pseudouridine synthase activity
FOE78_06325	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOE78_06350	COG0488	(ABC) transporter
FOE78_06375	COG0372	Belongs to the citrate synthase family
FOE78_06380	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOE78_06385	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOE78_06390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOE78_06400	COG5002	protein histidine kinase activity
FOE78_06405	COG0745	RESPONSE REGULATOR receiver
FOE78_06415	COG1072	(Pantothenic acid kinase))
FOE78_06420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOE78_06425	COG0736	holo-[acyl-carrier-protein] synthase activity
FOE78_06435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOE78_06450	COG1733	regulation of RNA biosynthetic process
FOE78_06455	COG0513	Belongs to the DEAD box helicase family
FOE78_06460	COG0802	atpase or kinase
FOE78_06475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOE78_06495	COG0616	signal peptide processing
FOE78_06505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOE78_06510	COG0459	protein refolding
FOE78_06515	COG1904	glucuronate isomerase
FOE78_06520	COG1609	Transcriptional regulator
FOE78_06530	COG0516	GMP reductase activity
FOE78_06545	COG2197	response regulator
FOE78_06560	COG0519	Catalyzes the synthesis of GMP from XMP
FOE78_06560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOE78_06585	COG2197	response regulator
FOE78_06605	COG0730	response to heat
FOE78_06610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOE78_06630	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOE78_06635	COG0045	succinate-CoA ligase (ADP-forming) activity
FOE78_06645	COG0561	phosphatase activity
FOE78_06690	COG0039	L-malate dehydrogenase activity
FOE78_06705	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOE78_06710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOE78_06720	COG1132	(ABC) transporter
FOE78_06725	COG1253	flavin adenine dinucleotide binding
FOE78_06730	COG0180	Tryptophanyl-tRNA synthetase
FOE78_06735	COG0477	Major facilitator Superfamily
FOE78_06765	COG0025	NhaP-type Na H and K H
FOE78_06775	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOE78_06775	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOE78_06785	COG1744	ABC transporter substrate-binding protein PnrA-like
FOE78_06820	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOE78_06825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOE78_06835	COG2814	Major facilitator Superfamily
FOE78_06850	COG1012	belongs to the aldehyde dehydrogenase family
FOE78_06855	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOE78_06870	COG2130	NADP-dependent
FOE78_06875	COG2183	response to ionizing radiation
FOE78_06890	COG1960	acyl-CoA dehydrogenase activity
FOE78_06900	COG1012	belongs to the aldehyde dehydrogenase family
FOE78_06930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOE78_06945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOE78_06955	COG2814	Major facilitator Superfamily
FOE78_06960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOE78_06975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOE78_06980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOE78_06990	COG2801	Transposase and inactivated derivatives
FOE78_07010	COG4770	biotin carboxylase activity
FOE78_07015	COG1984	allophanate hydrolase subunit 2
FOE78_07025	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FOE78_07035	COG1960	acyl-CoA dehydrogenase activity
FOE78_07040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOE78_07060	COG0528	UMP kinase activity
FOE78_07070	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_07075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FOE78_07105	COG0424	maF-like protein
FOE78_07115	COG0738	Major facilitator superfamily
FOE78_07120	COG0697	spore germination
FOE78_07140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOE78_07155	COG1024	Enoyl-CoA hydratase
FOE78_07165	COG1215	transferase activity, transferring glycosyl groups
FOE78_07175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOE78_07180	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_07210	COG0395	ABC-type sugar transport system, permease component
FOE78_07215	COG1175	transmembrane transport
FOE78_07220	COG1609	Transcriptional regulator
FOE78_07255	COG0673	inositol 2-dehydrogenase activity
FOE78_07270	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOE78_07270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOE78_07300	COG1116	anion transmembrane transporter activity
FOE78_07335	COG1316	TRANSCRIPTIONal
FOE78_07365	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
FOE78_07395	COG3718	enzyme involved in inositol metabolism
FOE78_07400	COG3962	Belongs to the TPP enzyme family
FOE78_07410	COG0673	inositol 2-dehydrogenase activity
FOE78_07430	COG0778	Nitroreductase
FOE78_07430	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FOE78_07490	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOE78_07520	COG0667	Aldo Keto reductase
FOE78_07525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FOE78_07550	COG2062	phosphohistidine phosphatase, SixA
FOE78_07555	COG0514	ATP-dependent DNA helicase (RecQ)
FOE78_07575	COG2814	Major facilitator Superfamily
FOE78_07610	COG1335	isochorismatase
FOE78_07620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOE78_07685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOE78_07705	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOE78_07710	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOE78_07715	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOE78_07725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOE78_07735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOE78_07755	COG0667	Aldo Keto reductase
FOE78_07800	COG0583	DNA-binding transcription factor activity
FOE78_07845	COG0494	nUDIX hydrolase
FOE78_07900	COG2801	Transposase and inactivated derivatives
FOE78_07915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOE78_07920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOE78_07925	COG4941	Belongs to the sigma-70 factor family
FOE78_07930	COG3795	YCII-related domain
FOE78_07960	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOE78_07975	COG0629	single-stranded DNA binding
FOE78_08005	COG0673	inositol 2-dehydrogenase activity
FOE78_08010	COG2838	Isocitrate dehydrogenase
FOE78_08030	COG0277	FAD linked oxidase domain protein
FOE78_08030	COG0247	lactate metabolic process
FOE78_08065	COG3347	Dehydrogenase
FOE78_08065	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_08070	COG4806	L-rhamnose isomerase
FOE78_08070	COG1070	Carbohydrate kinase
FOE78_08090	COG0277	FAD linked oxidase domain protein
FOE78_08100	COG1063	alcohol dehydrogenase
FOE78_08110	COG0277	FAD linked oxidase domain protein
FOE78_08115	COG1764	response to oxidative stress
FOE78_08120	COG0668	transmembrane transport
FOE78_08125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOE78_08130	COG0540	Belongs to the ATCase OTCase family
FOE78_08135	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FOE78_08150	COG2169	Transcriptional regulator
FOE78_08150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOE78_08165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOE78_08175	COG0698	ribose 5-phosphate isomerase
FOE78_08200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOE78_08245	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOE78_08245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOE78_08250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOE78_08280	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOE78_08295	COG0386	Belongs to the glutathione peroxidase family
FOE78_08300	COG0740	serine-type endopeptidase activity
FOE78_08305	COG0740	serine-type endopeptidase activity
FOE78_08310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOE78_08320	COG4209	transmembrane transport
FOE78_08325	COG0395	ABC-type sugar transport system, permease component
FOE78_08390	COG0525	valine-tRNA ligase activity
FOE78_08400	COG0285	dihydrofolate synthase activity
FOE78_08415	COG1309	transcriptional regulator
FOE78_08430	COG0584	glycerophosphoryl diester phosphodiesterase
FOE78_08435	COG3842	ATPase activity
FOE78_08440	COG3833	ABC-type maltose transport systems, permease component
FOE78_08455	COG0105	UTP biosynthetic process
FOE78_08460	COG1132	(ABC) transporter
FOE78_08470	COG2197	response regulator
FOE78_08475	COG2111	Na H antiporter
FOE78_08475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOE78_08490	COG1863	multisubunit Na H antiporter MnhE subunit
FOE78_08495	COG2212	antiporter activity
FOE78_08500	COG1320	monovalent cation:proton antiporter activity
FOE78_08565	COG0702	epimerase
FOE78_08610	COG3250	beta-galactosidase activity
FOE78_08615	COG1132	(ABC) transporter
FOE78_08620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOE78_08625	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOE78_08630	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOE78_08635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOE78_08655	COG4948	Mandelate Racemase Muconate Lactonizing
FOE78_08680	COG2205	protein histidine kinase activity
FOE78_08720	COG0601	transmembrane transport
FOE78_08735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOE78_08755	COG3833	ABC-type maltose transport systems, permease component
FOE78_08765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOE78_08780	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOE78_08785	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOE78_08790	COG0799	negative regulation of ribosome biogenesis
FOE78_08795	COG0406	alpha-ribazole phosphatase activity
FOE78_08830	COG0667	Aldo Keto reductase
FOE78_08845	COG0148	phosphopyruvate hydratase activity
FOE78_08855	COG1193	negative regulation of DNA recombination
FOE78_08860	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOE78_08940	COG5285	phytanoyl-CoA dioxygenase
FOE78_08970	COG2814	Major facilitator Superfamily
FOE78_09050	COG1850	ribulose-bisphosphate carboxylase activity
FOE78_09055	COG0747	negative chemotaxis
FOE78_09075	COG0601	transmembrane transport
FOE78_09115	COG3383	formate dehydrogenase (NAD+) activity
FOE78_09115	COG0243	molybdopterin cofactor binding
FOE78_09120	COG3383	formate dehydrogenase (NAD+) activity
FOE78_09120	COG0243	molybdopterin cofactor binding
FOE78_09125	COG0437	4 iron, 4 sulfur cluster binding
FOE78_09135	COG0709	Synthesizes selenophosphate from selenide and ATP
FOE78_09145	COG1921	L-seryl-tRNASec selenium transferase activity
FOE78_09175	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FOE78_09180	COG2814	Major facilitator Superfamily
FOE78_09220	COG2197	response regulator
FOE78_09225	COG1309	transcriptional regulator
FOE78_09230	COG1053	succinate dehydrogenase
FOE78_09235	COG2271	Major facilitator Superfamily
FOE78_09240	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOE78_09245	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOE78_09250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOE78_09255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOE78_09260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOE78_09265	COG1438	arginine binding
FOE78_09270	COG0165	Argininosuccinate lyase
FOE78_09275	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOE78_09325	COG2190	(PTS) system
FOE78_09325	COG2211	Major facilitator Superfamily
FOE78_09340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOE78_09345	COG1609	Transcriptional regulator
FOE78_09350	COG4213	ABC transporter substrate-binding protein
FOE78_09360	COG4214	carbohydrate transport
FOE78_09400	COG0438	transferase activity, transferring glycosyl groups
FOE78_09415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOE78_09420	COG1940	carbohydrate kinase activity
FOE78_09435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOE78_09440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOE78_09460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOE78_09485	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOE78_09500	COG0242	peptide deformylase activity
FOE78_09505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOE78_09515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOE78_09530	COG0640	Transcriptional regulator
FOE78_09540	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FOE78_09555	COG1175	transmembrane transport
FOE78_09560	COG0395	ABC-type sugar transport system, permease component
FOE78_09565	COG0495	leucyl-tRNA aminoacylation
FOE78_09570	COG1797	cobyrinic acid a,c-diamide synthase activity
FOE78_09585	COG1555	photosystem II stabilization
FOE78_09585	COG1596	polysaccharide export
FOE78_09590	COG2333	competence protein COMEC
FOE78_09590	COG0658	competence protein
FOE78_09595	COG1802	Transcriptional regulator
FOE78_09600	COG0402	S-adenosylhomocysteine deaminase activity
FOE78_09630	COG1012	belongs to the aldehyde dehydrogenase family
FOE78_09635	COG1309	transcriptional regulator
FOE78_09640	COG0028	Belongs to the TPP enzyme family
FOE78_09650	COG0268	Binds directly to 16S ribosomal RNA
FOE78_09660	COG3119	arylsulfatase activity
FOE78_09665	COG1501	Belongs to the glycosyl hydrolase 31 family
FOE78_09675	COG0395	ABC-type sugar transport system, permease component
FOE78_09680	COG4209	transmembrane transport
FOE78_09700	COG1053	succinate dehydrogenase
FOE78_09700	COG3976	FMN-binding domain protein
FOE78_09720	COG1073	alpha beta
FOE78_09725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOE78_09740	COG0481	GTPase activity
FOE78_09750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOE78_09755	COG0628	permease
FOE78_09760	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOE78_09765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOE78_09775	COG0745	RESPONSE REGULATOR receiver
FOE78_09825	COG1420	regulation of RNA biosynthetic process
FOE78_09830	COG0484	heat shock protein binding
FOE78_09840	COG0343	queuine tRNA-ribosyltransferase activity
FOE78_09865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOE78_09880	COG0477	Major facilitator Superfamily
FOE78_09890	COG0366	Alpha amylase catalytic
FOE78_09905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOE78_09915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOE78_09925	COG0673	inositol 2-dehydrogenase activity
FOE78_09930	COG0395	ABC-type sugar transport system, permease component
FOE78_09935	COG1175	transmembrane transport
FOE78_09940	COG1653	transport
FOE78_09950	COG1381	Involved in DNA repair and RecF pathway recombination
FOE78_09955	COG0583	DNA-binding transcription factor activity
FOE78_09965	COG4948	Mandelate Racemase Muconate Lactonizing
FOE78_09970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOE78_09985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOE78_09990	COG1121	(ABC) transporter
FOE78_09995	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOE78_09995	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOE78_10015	COG0423	glycine-tRNA ligase activity
FOE78_10030	COG1487	ribonuclease activity
FOE78_10050	COG3467	pyridoxamine 5'-phosphate
FOE78_10055	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOE78_10080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOE78_10090	COG4209	transmembrane transport
FOE78_10095	COG0395	ABC-type sugar transport system, permease component
FOE78_10100	COG1653	transport
FOE78_10130	COG0358	DNA primase activity
FOE78_10135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOE78_10140	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOE78_10165	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FOE78_10180	COG0667	Aldo Keto reductase
FOE78_10205	COG0579	oxidoreductase
FOE78_10230	COG0561	phosphatase activity
FOE78_10240	COG0714	Associated with various cellular activities
FOE78_10250	COG2304	oxidoreductase activity
FOE78_10255	COG2304	oxidoreductase activity
FOE78_10280	COG0714	Associated with various cellular activities
FOE78_10350	COG0405	Gamma-glutamyltransferase
FOE78_10355	COG0242	peptide deformylase activity
FOE78_10360	COG1228	amidohydrolase
FOE78_10370	COG4974	Belongs to the 'phage' integrase family
FOE78_10385	COG0741	lytic transglycosylase activity
FOE78_10385	COG0739	heme binding
FOE78_10385	COG1196	nuclear chromosome segregation
FOE78_10395	COG0052	Belongs to the universal ribosomal protein uS2 family
FOE78_10400	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOE78_10405	COG0528	UMP kinase activity
FOE78_10410	COG0233	cytoplasmic translational termination
FOE78_10450	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOE78_10480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOE78_10515	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOE78_10520	COG0750	zinc metalloprotease
FOE78_10525	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FOE78_10530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOE78_10545	COG0442	prolyl-tRNA aminoacylation
FOE78_10555	COG0779	Required for maturation of 30S ribosomal subunits
FOE78_10565	COG0363	glucosamine-6-phosphate deaminase activity
FOE78_10575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOE78_10575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOE78_10580	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOE78_10585	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOE78_10600	COG1105	Belongs to the carbohydrate kinase PfkB family
FOE78_10620	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOE78_10625	COG1185	polyribonucleotide nucleotidyltransferase activity
FOE78_10630	COG0612	Peptidase, M16
FOE78_10660	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOE78_10675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOE78_10680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOE78_10685	COG0351	phosphomethylpyrimidine kinase
FOE78_10685	COG0352	thiamine-phosphate diphosphorylase activity
FOE78_10685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOE78_10690	COG0351	phosphomethylpyrimidine kinase
FOE78_10695	COG0352	thiamine-phosphate diphosphorylase activity
FOE78_10700	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOE78_10715	COG0742	ribosomal rna small subunit methyltransferase
FOE78_10720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOE78_10735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOE78_10740	COG0571	ribonuclease III activity
FOE78_10745	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOE78_10760	COG0656	L-ascorbic acid biosynthetic process
FOE78_10820	COG4209	transmembrane transport
FOE78_10825	COG0395	ABC-type sugar transport system, permease component
FOE78_10830	COG0228	four-way junction DNA binding
FOE78_10835	COG1837	Belongs to the UPF0109 family
FOE78_10840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOE78_10845	COG0336	Belongs to the RNA methyltransferase TrmD family
FOE78_10870	COG2205	protein histidine kinase activity
FOE78_10875	COG0745	RESPONSE REGULATOR receiver
FOE78_10895	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOE78_10910	COG1053	succinate dehydrogenase
FOE78_10915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOE78_10920	COG1846	Transcriptional regulator
FOE78_10920	COG1940	carbohydrate kinase activity
FOE78_10930	COG0601	transmembrane transport
FOE78_10940	COG0444	Belongs to the ABC transporter superfamily
FOE78_10945	COG4608	Belongs to the ABC transporter superfamily
FOE78_10965	COG0488	(ABC) transporter
FOE78_10975	COG0335	large ribosomal subunit rRNA binding
FOE78_10985	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOE78_11005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOE78_11010	COG0667	Aldo Keto reductase
FOE78_11015	COG0792	nuclease activity
FOE78_11020	COG0606	chelatase, subunit chli
FOE78_11045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOE78_11050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOE78_11055	COG0800	Aldolase
FOE78_11070	COG4106	trans-aconitate 2-methyltransferase activity
FOE78_11075	COG0745	RESPONSE REGULATOR receiver
FOE78_11080	COG5002	protein histidine kinase activity
FOE78_11080	COG5000	phosphorelay sensor kinase activity
FOE78_11085	COG5401	PFAM Sporulation and spore germination
FOE78_11090	COG1040	competence protein
FOE78_11100	COG0395	ABC-type sugar transport system, permease component
FOE78_11110	COG2814	Major facilitator Superfamily
FOE78_11135	COG0477	Major facilitator Superfamily
FOE78_11150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOE78_11180	COG0653	protein targeting
FOE78_11185	COG3973	AAA domain
FOE78_11200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOE78_11215	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FOE78_11230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOE78_11265	COG2197	response regulator
FOE78_11275	COG0586	Pfam SNARE associated Golgi protein
FOE78_11280	COG0673	inositol 2-dehydrogenase activity
FOE78_11300	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FOE78_11305	COG1012	belongs to the aldehyde dehydrogenase family
FOE78_11325	COG2902	Dehydrogenase
FOE78_11330	COG0789	Transcriptional regulator
FOE78_11335	COG0477	Major facilitator Superfamily
FOE78_11360	COG0613	PHP domain protein
FOE78_11430	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_11435	COG2084	Dehydrogenase
FOE78_11440	COG1082	Xylose isomerase domain protein TIM barrel
FOE78_11475	COG0560	Phosphoserine phosphatase
FOE78_11475	COG3830	Belongs to the UPF0237 family
FOE78_11490	COG0210	DNA helicase
FOE78_11495	COG0210	DNA helicase
FOE78_11510	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOE78_11510	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOE78_11520	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FOE78_11525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOE78_11530	COG1074	ATP-dependent DNA helicase activity
FOE78_11540	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
FOE78_11580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOE78_11610	COG0667	Aldo Keto reductase
FOE78_11635	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOE78_11645	COG1615	UPF0182 protein
FOE78_11655	COG2801	Transposase and inactivated derivatives
FOE78_11670	COG0612	Peptidase, M16
FOE78_11675	COG3663	DNA glycosylase
FOE78_11685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOE78_11710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FOE78_11720	COG3119	arylsulfatase activity
FOE78_11755	COG0673	inositol 2-dehydrogenase activity
FOE78_11760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOE78_11775	COG1643	Atp-dependent helicase
FOE78_11790	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOE78_11795	COG1946	Acyl-CoA thioesterase
FOE78_11855	COG1309	transcriptional regulator
FOE78_11885	COG0589	response to stress
FOE78_11890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOE78_11915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOE78_11930	COG3485	protocatechuate 3,4-dioxygenase
FOE78_11935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOE78_11940	COG0483	inositol monophosphate 1-phosphatase activity
FOE78_11955	COG0444	Belongs to the ABC transporter superfamily
FOE78_11960	COG4608	Belongs to the ABC transporter superfamily
FOE78_11980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOE78_11990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOE78_11995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOE78_12005	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FOE78_12035	COG0395	ABC-type sugar transport system, permease component
FOE78_12040	COG4209	transmembrane transport
FOE78_12055	COG2002	toxin-antitoxin pair type II binding
FOE78_12065	COG1435	thymidine kinase activity
FOE78_12090	COG0322	excinuclease ABC activity
FOE78_12105	COG4867	von Willebrand factor, type A
FOE78_12125	COG1215	transferase activity, transferring glycosyl groups
FOE78_12140	COG1615	UPF0182 protein
FOE78_12165	COG2755	lipolytic protein G-D-S-L family
FOE78_12165	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOE78_12175	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOE78_12175	COG0463	Glycosyl transferase, family 2
FOE78_12250	COG2207	Transcriptional regulator
FOE78_12250	COG1609	Transcriptional regulator
FOE78_12290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOE78_12310	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOE78_12315	COG1929	Belongs to the glycerate kinase type-1 family
FOE78_12320	COG1506	peptidase
FOE78_12320	COG0823	Involved in the tonB-independent uptake of proteins
FOE78_12365	COG0569	domain protein
FOE78_12370	COG0531	amino acid
FOE78_12375	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOE78_12390	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOE78_12395	COG4221	oxidoreductase activity
FOE78_12405	COG0656	L-ascorbic acid biosynthetic process
FOE78_12420	COG0667	Aldo Keto reductase
FOE78_12490	COG3850	Histidine kinase
FOE78_12495	COG2197	response regulator
FOE78_12530	COG2814	Major facilitator Superfamily
FOE78_12535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOE78_12540	COG1011	Hydrolase
FOE78_12545	COG0673	inositol 2-dehydrogenase activity
FOE78_12555	COG1940	carbohydrate kinase activity
FOE78_12565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOE78_12575	COG1902	pentaerythritol trinitrate reductase activity
FOE78_12580	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOE78_12585	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOE78_12585	COG1024	Enoyl-CoA hydratase
FOE78_12590	COG0183	Belongs to the thiolase family
FOE78_12605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOE78_12620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOE78_12640	COG0529	Catalyzes the synthesis of activated sulfate
FOE78_12645	COG0175	sulfate reduction
FOE78_12670	COG3191	aminopeptidase activity
FOE78_12690	COG0747	negative chemotaxis
FOE78_12710	COG1129	ABC transporter
FOE78_12715	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOE78_12720	COG1879	ABC-type sugar transport system periplasmic component
FOE78_12725	COG2376	Dihydroxyacetone kinase
FOE78_12730	COG0698	ribose 5-phosphate isomerase
FOE78_12735	COG0149	triose-phosphate isomerase activity
FOE78_12760	COG1175	transmembrane transport
FOE78_12765	COG0395	ABC-type sugar transport system, permease component
FOE78_12775	COG1175	transmembrane transport
FOE78_12780	COG0395	ABC-type sugar transport system, permease component
FOE78_12785	COG1940	carbohydrate kinase activity
FOE78_12825	COG2721	sulfolactate sulfo-lyase activity
FOE78_12835	COG0697	spore germination
FOE78_12840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOE78_12865	COG0438	transferase activity, transferring glycosyl groups
FOE78_12885	COG0509	glycine decarboxylation via glycine cleavage system
FOE78_12890	COG1716	ATPase activity
FOE78_12915	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOE78_12915	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOE78_12920	COG2154	pterin-4-alpha-carbinolamine dehydratase
FOE78_12930	COG4608	Belongs to the ABC transporter superfamily
FOE78_12935	COG0444	Belongs to the ABC transporter superfamily
FOE78_12940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_12945	COG0601	transmembrane transport
FOE78_12950	COG0747	negative chemotaxis
FOE78_12955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOE78_12960	COG1295	ribonuclease BN
FOE78_12965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOE78_12970	COG0205	6-phosphofructokinase activity
FOE78_12975	COG0789	Transcriptional regulator
FOE78_12980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOE78_12985	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_12990	COG0477	Major facilitator Superfamily
FOE78_12995	COG0009	L-threonylcarbamoyladenylate synthase
FOE78_13000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOE78_13015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOE78_13020	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FOE78_13025	COG1295	ribonuclease BN
FOE78_13030	COG2909	trisaccharide binding
FOE78_13035	COG0490	domain, Protein
FOE78_13035	COG0471	metal ion transport
FOE78_13040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOE78_13055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOE78_13065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOE78_13080	COG2890	protein-(glutamine-N5) methyltransferase activity
FOE78_13085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOE78_13125	COG0747	negative chemotaxis
FOE78_13135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_13170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOE78_13175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOE78_13180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOE78_13185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOE78_13195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOE78_13200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOE78_13205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOE78_13230	COG1175	transmembrane transport
FOE78_13235	COG0395	ABC-type sugar transport system, permease component
FOE78_13250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOE78_13255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOE78_13275	COG0505	Belongs to the CarA family
FOE78_13280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOE78_13285	COG0167	dihydroorotate dehydrogenase activity
FOE78_13290	COG0284	orotidine-5'-phosphate decarboxylase activity
FOE78_13310	COG0194	GDP metabolic process
FOE78_13315	COG1758	RNA polymerase activity
FOE78_13325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOE78_13340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOE78_13345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOE78_13360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOE78_13375	COG1410	methionine synthase
FOE78_13375	COG0646	methionine synthase
FOE78_13380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOE78_13395	COG1222	aaa ATPase
FOE78_13410	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOE78_13415	COG0632	four-way junction helicase activity
FOE78_13425	COG2255	four-way junction helicase activity
FOE78_13430	COG1862	Preprotein translocase
FOE78_13435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOE78_13440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOE78_13445	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOE78_13455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOE78_13470	COG1196	nuclear chromosome segregation
FOE78_13475	COG0124	histidyl-tRNA synthetase
FOE78_13500	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FOE78_13510	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FOE78_13535	COG2197	response regulator
FOE78_13555	COG0659	secondary active sulfate transmembrane transporter activity
FOE78_13575	COG0628	permease
FOE78_13595	COG0659	secondary active sulfate transmembrane transporter activity
FOE78_13615	COG3119	arylsulfatase activity
FOE78_13630	COG0587	DNA-directed DNA polymerase activity
FOE78_13645	COG0745	RESPONSE REGULATOR receiver
FOE78_13650	COG2205	protein histidine kinase activity
FOE78_13660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOE78_13690	COG0598	Magnesium transport protein CorA
FOE78_13710	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOE78_13735	COG0706	membrane insertase activity
FOE78_13750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOE78_13820	COG2188	Transcriptional regulator
FOE78_13830	COG0516	GMP reductase activity
FOE78_13875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOE78_13885	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FOE78_13900	COG0584	glycerophosphoryl diester phosphodiesterase
FOE78_13925	COG2181	nitrate reductase activity
FOE78_13930	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOE78_13935	COG1140	nitrate reductase beta subunit
FOE78_13980	COG1522	sequence-specific DNA binding
FOE78_13985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOE78_14020	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOE78_14025	COG3328	transposase activity
FOE78_14030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOE78_14045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOE78_14075	COG0384	phenazine biosynthesis protein PhzF
FOE78_14085	COG1309	transcriptional regulator
FOE78_14090	COG0477	Major facilitator Superfamily
FOE78_14100	COG0667	Aldo Keto reductase
FOE78_14105	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FOE78_14110	COG1691	(AIR) carboxylase
FOE78_14115	COG1606	tRNA processing
FOE78_14120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOE78_14135	COG4989	oxidoreductase activity
FOE78_14145	COG2197	response regulator
FOE78_14165	COG1252	NADH dehydrogenase
FOE78_14170	COG3387	PFAM Glycoside hydrolase 15-related
FOE78_14175	COG1294	oxidase, subunit
FOE78_14180	COG1271	oxidase subunit
FOE78_14200	COG0805	protein transport
FOE78_14210	COG1160	GTP binding
FOE78_14220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOE78_14225	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_14235	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FOE78_14240	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FOE78_14260	COG4122	O-methyltransferase activity
FOE78_14270	COG0076	glutamate decarboxylase activity
FOE78_14290	COG1175	transmembrane transport
FOE78_14295	COG0395	ABC-type sugar transport system, permease component
FOE78_14300	COG0217	transcriptional regulatory protein
FOE78_14330	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOE78_14365	COG2089	acid synthase
FOE78_14380	COG3290	protein histidine kinase activity
FOE78_14385	COG1116	anion transmembrane transporter activity
FOE78_14390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOE78_14410	COG0131	Imidazoleglycerol-phosphate dehydratase
FOE78_14415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOE78_14420	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOE78_14425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOE78_14430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOE78_14435	COG3285	dna ligase
FOE78_14435	COG1793	dna ligase
FOE78_14450	COG0587	DNA-directed DNA polymerase activity
FOE78_14465	COG0070	glutamate synthase
FOE78_14465	COG0069	glutamate synthase activity
FOE78_14465	COG0067	glutamate synthase
FOE78_14480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOE78_14495	COG2161	toxin-antitoxin pair type II binding
FOE78_14500	COG2026	Addiction module toxin, RelE StbE family
FOE78_14520	COG0159	tryptophan synthase activity
FOE78_14525	COG0133	tryptophan synthase activity
FOE78_14530	COG0134	indole-3-glycerol-phosphate synthase activity
FOE78_14545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOE78_14550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOE78_14570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOE78_14575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOE78_14580	COG0154	amidase activity
FOE78_14585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOE78_14615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOE78_14630	COG0557	exoribonuclease II activity
FOE78_14640	COG0482	sulfurtransferase activity
FOE78_14675	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOE78_14685	COG1472	Belongs to the glycosyl hydrolase 3 family
FOE78_14690	COG1609	Transcriptional regulator
FOE78_14730	COG0366	Alpha amylase catalytic
FOE78_14735	COG3281	Trehalose synthase
FOE78_14740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOE78_14800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOE78_14805	COG2226	methyltransferase
FOE78_14810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOE78_14840	COG1846	Transcriptional regulator
FOE78_14855	COG0183	Belongs to the thiolase family
FOE78_14860	COG0346	lactoylglutathione lyase activity
FOE78_14885	COG1129	ABC transporter
FOE78_14885	COG0842	Transport permease protein
FOE78_14910	COG3848	Pyruvate phosphate dikinase
FOE78_14910	COG0574	Belongs to the PEP-utilizing enzyme family
FOE78_14945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOE78_14950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOE78_14955	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOE78_14960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOE78_14965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOE78_14970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOE78_14975	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOE78_14980	COG0356	it plays a direct role in the translocation of protons across the membrane
FOE78_15005	COG2890	protein-(glutamine-N5) methyltransferase activity
FOE78_15025	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOE78_15030	COG0254	rRNA binding
FOE78_15040	COG0083	homoserine kinase activity
FOE78_15045	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOE78_15050	COG0460	homoserine dehydrogenase
FOE78_15055	COG0019	diaminopimelate decarboxylase activity
FOE78_15085	COG0237	dephospho-CoA kinase activity
FOE78_15115	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOE78_15115	COG0567	Dehydrogenase, E1 component
FOE78_15130	COG1609	Transcriptional regulator
FOE78_15175	COG4608	Belongs to the ABC transporter superfamily
FOE78_15180	COG0444	Belongs to the ABC transporter superfamily
FOE78_15185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_15195	COG0747	negative chemotaxis
FOE78_15200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOE78_15210	COG4677	pectinesterase activity
FOE78_15295	COG1609	Transcriptional regulator
FOE78_15320	COG1064	alcohol dehydrogenase
FOE78_15325	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOE78_15335	COG0765	amino acid transport
FOE78_15340	COG1126	abc transporter atp-binding protein
FOE78_15350	COG4948	Mandelate Racemase Muconate Lactonizing
FOE78_15380	COG0667	Aldo Keto reductase
FOE78_15395	COG1595	DNA-templated transcription, initiation
FOE78_15425	COG2135	peptidase activity
FOE78_15435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOE78_15440	COG1162	GTPase activity
FOE78_15445	COG0483	inositol monophosphate 1-phosphatase activity
FOE78_15450	COG4948	Mandelate Racemase Muconate Lactonizing
FOE78_15455	COG1289	transmembrane transporter activity
FOE78_15480	COG0583	DNA-binding transcription factor activity
FOE78_15500	COG4608	Belongs to the ABC transporter superfamily
FOE78_15505	COG0444	Belongs to the ABC transporter superfamily
FOE78_15510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_15515	COG0601	transmembrane transport
FOE78_15520	COG4166	transmembrane transport
FOE78_15550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOE78_15555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOE78_15575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOE78_15580	COG4607	ABC-type enterochelin transport system periplasmic component
FOE78_15600	COG0596	Alpha beta hydrolase
FOE78_15610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOE78_15620	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOE78_15635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOE78_15645	COG1528	Iron-storage protein
FOE78_15650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOE78_15655	COG2017	converts alpha-aldose to the beta-anomer
FOE78_15660	COG0405	Gamma-glutamyltransferase
FOE78_15665	COG1126	abc transporter atp-binding protein
FOE78_15670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOE78_15675	COG0765	amino acid transport
FOE78_15680	COG0765	amino acid transport
FOE78_15685	COG1418	mRNA catabolic process
FOE78_15740	COG2137	regulation of response to DNA damage stimulus
FOE78_15750	COG0477	Major facilitator Superfamily
FOE78_15790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOE78_15795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOE78_15800	COG0006	proline dipeptidase activity
FOE78_15810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOE78_15815	COG0154	amidase activity
FOE78_15830	COG3579	cysteine-type endopeptidase activity
FOE78_15855	COG1201	RNA secondary structure unwinding
FOE78_15865	COG1396	sequence-specific DNA binding
FOE78_15870	COG1058	Belongs to the CinA family
FOE78_15870	COG1546	Belongs to the CinA family
FOE78_15880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOE78_15895	COG2814	Major facilitator Superfamily
FOE78_15900	COG1674	ftsk spoiiie
FOE78_15905	COG4166	transmembrane transport
FOE78_15910	COG0601	transmembrane transport
FOE78_15915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_15920	COG0444	Belongs to the ABC transporter superfamily
FOE78_15925	COG4608	Belongs to the ABC transporter superfamily
FOE78_15955	COG0346	lactoylglutathione lyase activity
FOE78_15965	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FOE78_15975	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOE78_15980	COG2066	Belongs to the glutaminase family
FOE78_16000	COG0628	permease
FOE78_16025	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOE78_16030	COG0626	cystathionine gamma-synthase activity
FOE78_16040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOE78_16050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOE78_16055	COG0204	Acyl-transferase
FOE78_16055	COG0318	PFAM AMP-dependent synthetase and ligase
FOE78_16065	COG0776	regulation of translation
FOE78_16070	COG0066	3-isopropylmalate dehydratase activity
FOE78_16075	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOE78_16080	COG1414	Transcriptional regulator
FOE78_16110	COG1266	CAAX protease self-immunity
FOE78_16115	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FOE78_16115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOE78_16120	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOE78_16140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOE78_16155	COG3250	beta-galactosidase activity
FOE78_16165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOE78_16170	COG0473	3-isopropylmalate dehydrogenase activity
FOE78_16185	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOE78_16190	COG0440	acetolactate synthase activity
FOE78_16215	COG0589	response to stress
FOE78_16230	COG1051	belongs to the nudix hydrolase family
FOE78_16235	COG0537	adenosine 5'-monophosphoramidase activity
FOE78_16240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOE78_16245	COG0107	imidazoleglycerol-phosphate synthase activity
FOE78_16260	COG0346	lactoylglutathione lyase activity
FOE78_16270	COG4581	dead DEAH box helicase
FOE78_16280	COG2161	toxin-antitoxin pair type II binding
FOE78_16290	COG0805	protein transport
FOE78_16295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOE78_16315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOE78_16335	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FOE78_16345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOE78_16375	COG0686	Belongs to the AlaDH PNT family
FOE78_16380	COG1957	nucleoside hydrolase
FOE78_16420	COG0504	CTP synthase activity
FOE78_16470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOE78_16490	COG0647	UMP catabolic process
FOE78_16510	COG1349	DNA-binding transcription factor activity
FOE78_16525	COG0395	ABC-type sugar transport system, permease component
FOE78_16535	COG1070	Carbohydrate kinase
FOE78_16560	COG0583	DNA-binding transcription factor activity
FOE78_16570	COG3328	transposase activity
FOE78_16585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOE78_16600	COG0072	phenylalanine-tRNA ligase activity
FOE78_16600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOE78_16605	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOE78_16625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOE78_16630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOE78_16635	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOE78_16640	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOE78_16660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOE78_16665	COG0140	phosphoribosyl-ATP diphosphatase activity
FOE78_16675	COG0215	cysteine-tRNA ligase activity
FOE78_16700	COG1968	undecaprenyl-diphosphatase activity
FOE78_16705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOE78_16710	COG0667	Aldo Keto reductase
FOE78_16725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOE78_16760	COG1959	2 iron, 2 sulfur cluster binding
FOE78_16765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOE78_16765	COG1017	nitric oxide dioxygenase activity
FOE78_16775	COG1082	Xylose isomerase domain protein TIM barrel
FOE78_16825	COG0395	ABC-type sugar transport system, permease component
FOE78_16840	COG5002	protein histidine kinase activity
FOE78_16845	COG0745	RESPONSE REGULATOR receiver
FOE78_16855	COG0444	Belongs to the ABC transporter superfamily
FOE78_16860	COG4608	Belongs to the ABC transporter superfamily
FOE78_16865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_16870	COG0601	transmembrane transport
FOE78_16880	COG0183	Belongs to the thiolase family
FOE78_16890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOE78_16920	COG0318	PFAM AMP-dependent synthetase and ligase
FOE78_16925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOE78_16950	COG1122	ATPase activity
FOE78_16965	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOE78_16970	COG1737	Transcriptional regulator
FOE78_16980	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FOE78_16985	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FOE78_16990	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FOE78_17010	COG1678	Uncharacterized ACR, COG1678
FOE78_17020	COG1609	Transcriptional regulator
FOE78_17030	COG0300	oxidoreductase activity
FOE78_17060	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FOE78_17085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOE78_17095	COG0180	Tryptophanyl-tRNA synthetase
FOE78_17105	COG3507	Belongs to the glycosyl hydrolase 43 family
FOE78_17125	COG2177	Part of the ABC transporter FtsEX involved in
FOE78_17130	COG2884	Cell division ATP-binding protein ftsE
FOE78_17140	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FOE78_17145	COG1940	carbohydrate kinase activity
FOE78_17160	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_17190	COG4209	transmembrane transport
FOE78_17195	COG0395	ABC-type sugar transport system, permease component
FOE78_17205	COG0673	inositol 2-dehydrogenase activity
FOE78_17225	COG0673	inositol 2-dehydrogenase activity
FOE78_17235	COG1609	Transcriptional regulator
FOE78_17240	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOE78_17250	COG1063	alcohol dehydrogenase
FOE78_17280	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOE78_17295	COG1796	DNA polymerase
FOE78_17295	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOE78_17310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOE78_17335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOE78_17345	COG1486	melibiose metabolic process
FOE78_17355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOE78_17360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOE78_17360	COG1648	precorrin-2 dehydrogenase activity
FOE78_17365	COG0789	Transcriptional regulator
FOE78_17370	COG0071	Belongs to the small heat shock protein (HSP20) family
FOE78_17390	COG1119	ATPase activity
FOE78_17405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOE78_17415	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_17430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOE78_17440	COG1132	(ABC) transporter
FOE78_17445	COG1132	(ABC) transporter
FOE78_17450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOE78_17465	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_17470	COG2226	methyltransferase
FOE78_17475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOE78_17490	COG1132	(ABC) transporter
FOE78_17500	COG0488	(ABC) transporter
FOE78_17535	COG0028	Belongs to the TPP enzyme family
FOE78_17540	COG4948	Mandelate Racemase Muconate Lactonizing
FOE78_17550	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FOE78_17555	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_17605	COG0651	ATP synthesis coupled electron transport
FOE78_17615	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_17620	COG0783	Belongs to the Dps family
FOE78_17625	COG3387	PFAM Glycoside hydrolase 15-related
FOE78_17660	COG2271	Major facilitator Superfamily
FOE78_17675	COG2151	metal-sulfur cluster biosynthetic enzyme
FOE78_17685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOE78_17690	COG0396	ATPase activity
FOE78_17720	COG1793	dna ligase
FOE78_17725	COG1131	(ABC) transporter
FOE78_17750	COG0109	protoheme IX farnesyltransferase activity
FOE78_17760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOE78_17775	COG0363	glucosamine-6-phosphate deaminase activity
FOE78_17785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOE78_17795	COG3328	transposase activity
FOE78_17830	COG2318	DinB family
FOE78_17840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOE78_17845	COG0149	triose-phosphate isomerase activity
FOE78_17850	COG0126	phosphoglycerate kinase activity
FOE78_17860	COG1481	regulation of sporulation
FOE78_17875	COG1660	Displays ATPase and GTPase activities
FOE78_17885	COG0322	excinuclease ABC activity
FOE78_17890	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_17895	COG1309	transcriptional regulator
FOE78_17900	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOE78_17905	COG0800	Aldolase
FOE78_17915	COG0723	plastoquinol--plastocyanin reductase activity
FOE78_17920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOE78_17935	COG1309	transcriptional regulator
FOE78_17950	COG0861	Integral membrane protein TerC family
FOE78_17960	COG4941	Belongs to the sigma-70 factor family
FOE78_17965	COG3795	YCII-related domain
FOE78_17970	COG0556	nucleotide-excision repair
FOE78_17985	COG0237	dephospho-CoA kinase activity
FOE78_17990	COG0539	negative regulation of cytoplasmic translation
FOE78_17995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOE78_18025	COG2197	response regulator
FOE78_18030	COG4585	Histidine kinase
FOE78_18045	COG0823	Involved in the tonB-independent uptake of proteins
FOE78_18050	COG3401	FG-GAP repeat protein
FOE78_18055	COG0395	ABC-type sugar transport system, permease component
FOE78_18060	COG4209	transmembrane transport
FOE78_18065	COG1653	transport
FOE78_18090	COG2050	protein possibly involved in aromatic compounds catabolism
FOE78_18095	COG2226	methyltransferase
FOE78_18105	COG0410	ABC transporter
FOE78_18110	COG0411	ABC transporter
FOE78_18120	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOE78_18140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOE78_18180	COG1799	cell septum assembly
FOE78_18185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOE78_18190	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOE78_18195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOE78_18200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOE78_18210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOE78_18215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOE78_18225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOE78_18230	COG0768	penicillin binding
FOE78_18240	COG0275	rRNA processing
FOE78_18245	COG2001	Belongs to the MraZ family
FOE78_18250	COG0714	Associated with various cellular activities
FOE78_18285	COG2124	cytochrome p450
FOE78_18290	COG1233	COG1233 Phytoene dehydrogenase and related
FOE78_18295	COG3973	AAA domain
FOE78_18315	COG0596	Alpha beta hydrolase
FOE78_18330	COG0640	Transcriptional regulator
FOE78_18350	COG0673	inositol 2-dehydrogenase activity
FOE78_18355	COG1609	Transcriptional regulator
FOE78_18370	COG0352	thiamine-phosphate diphosphorylase activity
FOE78_18410	COG1484	DNA-dependent DNA replication
FOE78_18430	COG2815	serine threonine protein kinase
FOE78_18430	COG0515	serine threonine protein kinase
FOE78_18435	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOE78_18440	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FOE78_18460	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_18465	COG1309	transcriptional regulator
FOE78_18470	COG0477	Major facilitator Superfamily
FOE78_18475	COG3104	oligopeptide transport
FOE78_18485	COG1940	carbohydrate kinase activity
FOE78_18515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOE78_18540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOE78_18565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOE78_18575	COG1845	cytochrome c oxidase, subunit III
FOE78_18580	COG2010	Cytochrome c
FOE78_18585	COG0723	plastoquinol--plastocyanin reductase activity
FOE78_18590	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOE78_18610	COG0435	Glutathione S-transferase
FOE78_18680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOE78_18685	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOE78_18710	COG3386	PFAM SMP-30 Gluconolaconase
FOE78_18715	COG0129	dihydroxy-acid dehydratase activity
FOE78_18735	COG0667	Aldo Keto reductase
FOE78_18745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOE78_18765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOE78_18770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOE78_18780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOE78_18785	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOE78_18790	COG1090	epimerase
FOE78_18795	COG0321	lipoyl(octanoyl) transferase activity
FOE78_18820	COG0596	Alpha beta hydrolase
FOE78_18830	COG4607	ABC-type enterochelin transport system periplasmic component
FOE78_18850	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOE78_18865	COG0488	(ABC) transporter
FOE78_18870	COG0726	polysaccharide deacetylase
FOE78_18880	COG0277	FAD linked oxidase domain protein
FOE78_18905	COG1129	ABC transporter
FOE78_18905	COG0842	Transport permease protein
FOE78_18915	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOE78_18920	COG0667	Aldo Keto reductase
FOE78_18925	COG0174	glutamine synthetase
FOE78_18940	COG3384	dioxygenase
FOE78_18990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOE78_18995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOE78_19000	COG1012	belongs to the aldehyde dehydrogenase family
FOE78_19005	COG0438	transferase activity, transferring glycosyl groups
FOE78_19010	COG3387	PFAM Glycoside hydrolase 15-related
FOE78_19015	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOE78_19055	COG3119	arylsulfatase activity
FOE78_19095	COG0789	Transcriptional regulator
FOE78_19140	COG4115	mRNA cleavage
FOE78_19155	COG1733	regulation of RNA biosynthetic process
FOE78_19160	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOE78_19165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOE78_19205	COG0402	S-adenosylhomocysteine deaminase activity
FOE78_19220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOE78_19225	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOE78_19240	COG0549	Belongs to the carbamate kinase family
FOE78_19245	COG1228	amidohydrolase
FOE78_19260	COG0402	S-adenosylhomocysteine deaminase activity
FOE78_19265	COG0666	response to abiotic stimulus
FOE78_19295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOE78_19300	COG3511	phospholipase C
FOE78_19305	COG1228	amidohydrolase
FOE78_19315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOE78_19320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOE78_19325	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOE78_19350	COG0531	amino acid
FOE78_19360	COG2011	ABC-type metal ion transport system permease component
FOE78_19365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOE78_19370	COG1464	Belongs to the NlpA lipoprotein family
FOE78_19405	COG0596	Alpha beta hydrolase
FOE78_19410	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOE78_19410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOE78_19445	COG3328	transposase activity
FOE78_19460	COG1131	(ABC) transporter
FOE78_19500	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_19520	COG0659	secondary active sulfate transmembrane transporter activity
FOE78_19525	COG0789	Transcriptional regulator
FOE78_19535	COG0604	alcohol dehydrogenase
FOE78_19535	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_19535	COG3321	synthase
FOE78_19550	COG2814	Major facilitator Superfamily
FOE78_19555	COG0406	alpha-ribazole phosphatase activity
FOE78_19565	COG0006	proline dipeptidase activity
FOE78_19580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOE78_19585	COG2197	response regulator
FOE78_19590	COG4585	Histidine kinase
FOE78_19600	COG2239	Acts as a magnesium transporter
FOE78_19610	COG1953	Uracil, thiamine, allantoin
FOE78_19630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOE78_19635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOE78_19650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOE78_19665	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
FOE78_19675	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOE78_19680	COG0297	glycogen (starch) synthase activity
FOE78_19705	COG2818	Glycosylase
FOE78_19720	COG2171	N-acyltransferase activity
FOE78_19765	COG1472	Belongs to the glycosyl hydrolase 3 family
FOE78_19800	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOE78_19815	COG4608	Belongs to the ABC transporter superfamily
FOE78_19825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_19830	COG0601	transmembrane transport
FOE78_19835	COG0747	negative chemotaxis
FOE78_19860	COG2197	response regulator
FOE78_19865	COG1595	DNA-templated transcription, initiation
FOE78_19890	COG4552	Acetyltransferase involved in intracellular survival and related
FOE78_19900	COG1611	Belongs to the LOG family
FOE78_19915	COG2211	Major facilitator Superfamily
FOE78_19935	COG0012	GTP binding
FOE78_19945	COG1362	aminopeptidase activity
FOE78_19950	COG1322	Protein conserved in bacteria
FOE78_19955	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOE78_19970	COG1309	transcriptional regulator
FOE78_19975	COG1570	exodeoxyribonuclease VII activity
FOE78_19980	COG1722	exodeoxyribonuclease VII activity
FOE78_19985	COG4977	sequence-specific DNA binding
FOE78_20000	COG0114	fumarate hydratase activity
FOE78_20020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOE78_20030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOE78_20050	COG1331	Highly conserved protein containing a thioredoxin domain
FOE78_20055	COG0531	amino acid
FOE78_20075	COG0667	Aldo Keto reductase
FOE78_20110	COG0129	dihydroxy-acid dehydratase activity
FOE78_20125	COG1653	transport
FOE78_20130	COG3119	arylsulfatase activity
FOE78_20135	COG0531	amino acid
FOE78_20145	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_20155	COG2186	Transcriptional regulator
FOE78_20165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOE78_20175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOE78_20200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOE78_20210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOE78_20215	COG0412	Dienelactone hydrolase
FOE78_20245	COG0588	phosphoglycerate mutase activity
FOE78_20250	COG4941	Belongs to the sigma-70 factor family
FOE78_20285	COG0564	pseudouridine synthase activity
FOE78_20310	COG0242	peptide deformylase activity
FOE78_20315	COG3830	Belongs to the UPF0237 family
FOE78_20335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_20340	COG0601	transmembrane transport
FOE78_20355	COG0148	phosphopyruvate hydratase activity
FOE78_20405	COG0193	aminoacyl-tRNA hydrolase activity
FOE78_20410	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOE78_20415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOE78_20420	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOE78_20460	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOE78_20465	COG1846	Transcriptional regulator
FOE78_20475	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOE78_20480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOE78_20485	COG3583	domain protein
FOE78_20490	COG0778	Nitroreductase
FOE78_20495	COG0084	hydrolase, TatD family'
FOE78_20520	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOE78_20535	COG2197	response regulator
FOE78_20545	COG1472	Belongs to the glycosyl hydrolase 3 family
FOE78_20590	COG1649	PFAM Uncharacterised BCR, COG1649
FOE78_20600	COG2076	Multidrug Resistance protein
FOE78_20680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOE78_20685	COG3328	transposase activity
FOE78_20690	COG2267	carboxylic ester hydrolase activity
FOE78_20700	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_20710	COG3328	transposase activity
FOE78_20745	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOE78_20750	COG0315	cyclic pyranopterin monophosphate synthase activity
FOE78_20760	COG1793	dna ligase
FOE78_20760	COG3285	dna ligase
FOE78_20765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOE78_20770	COG4941	Belongs to the sigma-70 factor family
FOE78_20790	COG2755	lipolytic protein G-D-S-L family
FOE78_20790	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOE78_20800	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOE78_20805	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOE78_20825	COG1733	regulation of RNA biosynthetic process
FOE78_20845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOE78_20870	COG2366	antibiotic biosynthetic process
FOE78_20900	COG0247	lactate metabolic process
FOE78_20905	COG1139	Iron-sulfur cluster binding protein
FOE78_20910	COG1556	Lactate utilization protein
FOE78_20915	COG0778	Nitroreductase
FOE78_20970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOE78_20975	COG2226	methyltransferase
FOE78_20990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOE78_21005	COG1349	DNA-binding transcription factor activity
FOE78_21060	COG0259	pyridoxamine-phosphate oxidase activity
FOE78_21065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOE78_21080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOE78_21100	COG3119	arylsulfatase activity
FOE78_21105	COG2814	Major facilitator Superfamily
FOE78_21135	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOE78_21185	COG0601	transmembrane transport
FOE78_21200	COG4172	Belongs to the ABC transporter superfamily
FOE78_21210	COG2801	Transposase and inactivated derivatives
FOE78_21235	COG2814	Major facilitator Superfamily
FOE78_21245	COG1846	Transcriptional regulator
FOE78_21255	COG2382	esterase
FOE78_21280	COG2814	Major facilitator Superfamily
FOE78_21295	COG2326	polyphosphate kinase activity
FOE78_21300	COG2252	PERMEase
FOE78_21305	COG1278	Cold shock
FOE78_21315	COG0477	Major facilitator Superfamily
FOE78_21325	COG2133	pyrroloquinoline quinone binding
FOE78_21345	COG1061	Type III restriction enzyme res subunit
FOE78_21375	COG1051	belongs to the nudix hydrolase family
FOE78_21380	COG3973	AAA domain
FOE78_21390	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOE78_21410	COG0328	RNA-DNA hybrid ribonuclease activity
FOE78_21415	COG2866	Carboxypeptidase
FOE78_21425	COG0459	protein refolding
FOE78_21430	COG1484	DNA-dependent DNA replication
FOE78_21450	COG2814	Major facilitator Superfamily
FOE78_21470	COG0277	FAD linked oxidase domain protein
FOE78_21495	COG0514	ATP-dependent DNA helicase (RecQ)
FOE78_21500	COG0477	Major facilitator Superfamily
FOE78_21520	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOE78_21545	COG0673	inositol 2-dehydrogenase activity
FOE78_21550	COG1482	cell wall glycoprotein biosynthetic process
FOE78_21555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOE78_21570	COG2197	response regulator
FOE78_21585	COG4106	trans-aconitate 2-methyltransferase activity
FOE78_21600	COG0318	PFAM AMP-dependent synthetase and ligase
FOE78_21605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOE78_21645	COG1063	alcohol dehydrogenase
FOE78_21650	COG1760	l-serine dehydratase
FOE78_21655	COG3842	ATPase activity
FOE78_21675	COG1960	acyl-CoA dehydrogenase activity
FOE78_21685	COG0215	cysteine-tRNA ligase activity
FOE78_21695	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOE78_21705	COG0346	lactoylglutathione lyase activity
FOE78_21710	COG0640	Transcriptional regulator
FOE78_21715	COG0823	Involved in the tonB-independent uptake of proteins
FOE78_21720	COG1278	Cold shock
FOE78_21730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOE78_21750	COG1609	Transcriptional regulator
FOE78_21755	COG3534	alpha-L-arabinofuranosidase
FOE78_21760	COG1028	Short-chain dehydrogenase reductase Sdr
FOE78_21780	COG1175	transmembrane transport
FOE78_21800	COG1051	belongs to the nudix hydrolase family
FOE78_21805	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOE78_21815	COG2321	neutral zinc metallopeptidase
FOE78_21820	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOE78_21825	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOE78_21830	COG1329	Transcriptional regulator
FOE78_21840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOE78_21870	COG5002	protein histidine kinase activity
FOE78_21875	COG0704	Plays a role in the regulation of phosphate uptake
FOE78_21880	COG0588	phosphoglycerate mutase activity
FOE78_21895	COG2814	Major facilitator Superfamily
FOE78_21915	COG1160	GTP binding
FOE78_21925	COG1793	dna ligase
FOE78_21925	COG3285	dna ligase
FOE78_21990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOE78_21995	COG3485	protocatechuate 3,4-dioxygenase
FOE78_22010	COG1490	D-aminoacyl-tRNA deacylase activity
FOE78_22035	COG0745	RESPONSE REGULATOR receiver
FOE78_22065	COG0395	ABC-type sugar transport system, permease component
FOE78_22085	COG1309	transcriptional regulator
FOE78_22095	COG0456	acetyltransferase
FOE78_22100	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOE78_22145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOE78_22150	COG2326	polyphosphate kinase activity
FOE78_22175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOE78_22180	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOE78_22180	COG0456	acetyltransferase
FOE78_22210	COG1472	Belongs to the glycosyl hydrolase 3 family
FOE78_22220	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOE78_22240	COG0494	nUDIX hydrolase
FOE78_22255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOE78_22265	COG0785	Cytochrome C biogenesis protein
FOE78_22270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOE78_22275	COG0406	alpha-ribazole phosphatase activity
FOE78_22280	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOE78_22285	COG0113	porphobilinogen synthase activity
FOE78_22310	COG0181	hydroxymethylbilane synthase activity
FOE78_22315	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOE78_22320	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FOE78_22340	COG1140	nitrate reductase beta subunit
FOE78_22360	COG3254	rhamnose metabolic process
FOE78_22370	COG0560	Phosphoserine phosphatase
FOE78_22390	COG0129	dihydroxy-acid dehydratase activity
FOE78_22395	COG2197	response regulator
FOE78_22400	COG4585	Histidine kinase
FOE78_22415	COG2801	Transposase and inactivated derivatives
FOE78_22425	COG0318	PFAM AMP-dependent synthetase and ligase
FOE78_22450	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOE78_22455	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOE78_22470	COG1082	Xylose isomerase domain protein TIM barrel
FOE78_22485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOE78_22505	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOE78_22510	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FOE78_22520	COG2020	methyltransferase activity
FOE78_22550	COG1088	dTDP-glucose 4,6-dehydratase activity
FOE78_22555	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOE78_22560	COG0667	Aldo Keto reductase
FOE78_22580	COG0477	Major facilitator Superfamily
FOE78_22605	COG3448	diguanylate cyclase activity
FOE78_22605	COG4175	Glycine betaine
FOE78_22610	COG0673	inositol 2-dehydrogenase activity
FOE78_22615	COG0673	inositol 2-dehydrogenase activity
FOE78_22620	COG4209	transmembrane transport
FOE78_22625	COG0395	ABC-type sugar transport system, permease component
FOE78_22650	COG1595	DNA-templated transcription, initiation
FOE78_22660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOE78_22670	COG0142	geranyltranstransferase activity
FOE78_22675	COG1007	ATP synthesis coupled electron transport
FOE78_22690	COG0713	ATP synthesis coupled electron transport
FOE78_22705	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOE78_22710	COG1034	ATP synthesis coupled electron transport
FOE78_22725	COG0649	NAD binding
FOE78_22730	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOE78_22735	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOE78_22745	COG0644	oxidoreductase
FOE78_22755	COG1169	isochorismate synthase
FOE78_22765	COG0740	serine-type endopeptidase activity
FOE78_22770	COG0740	serine-type endopeptidase activity
FOE78_22780	COG2409	Drug exporters of the RND superfamily
FOE78_22785	COG1396	sequence-specific DNA binding
FOE78_22810	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOE78_22815	COG4948	Mandelate Racemase Muconate Lactonizing
FOE78_22825	COG1575	Belongs to the MenA family. Type 1 subfamily
FOE78_22830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOE78_22850	COG0746	molybdenum cofactor guanylyltransferase activity
FOE78_22860	COG3265	gluconokinase activity
FOE78_22865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOE78_22895	COG2814	Major facilitator Superfamily
FOE78_22915	COG1175	transmembrane transport
FOE78_22920	COG0395	ABC-type sugar transport system, permease component
FOE78_22940	COG1802	Transcriptional regulator
FOE78_22980	COG3103	Sh3 type 3 domain protein
FOE78_22980	COG1388	LysM domain
FOE78_22980	COG0791	NLP P60 protein
FOE78_23005	COG1733	regulation of RNA biosynthetic process
FOE78_23030	COG1252	NADH dehydrogenase
FOE78_23070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOE78_23075	COG1132	(ABC) transporter
FOE78_23080	COG1132	(ABC) transporter
FOE78_23085	COG2197	response regulator
FOE78_23090	COG4585	Histidine kinase
FOE78_23115	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOE78_23120	COG0640	Transcriptional regulator
FOE78_23140	COG0047	phosphoribosylformylglycinamidine synthase activity
FOE78_23145	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOE78_23165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOE78_23185	COG1131	(ABC) transporter
FOE78_23215	COG3655	Transcriptional regulator
FOE78_23225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOE78_23230	COG0151	Belongs to the GarS family
FOE78_23235	COG0747	negative chemotaxis
FOE78_23240	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOE78_23265	COG2188	Transcriptional regulator
FOE78_23270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOE78_23290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOE78_23295	COG2814	Major facilitator Superfamily
FOE78_23310	COG0586	Pfam SNARE associated Golgi protein
FOE78_23320	COG0667	Aldo Keto reductase
FOE78_23325	COG1704	LemA family
FOE78_23330	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOE78_23335	COG3764	Sortase (surface protein transpeptidase)
FOE78_23350	COG1940	carbohydrate kinase activity
FOE78_23360	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOE78_23365	COG0346	lactoylglutathione lyase activity
FOE78_23370	COG0542	response to heat
FOE78_23380	COG0439	Biotin carboxylase
FOE78_23395	COG0667	Aldo Keto reductase
FOE78_23400	COG1802	Transcriptional regulator
FOE78_23410	COG2271	Major facilitator Superfamily
FOE78_23420	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOE78_23430	COG4208	sulfate ABC transporter
FOE78_23435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOE78_23450	COG0789	Transcriptional regulator
FOE78_23455	COG0484	heat shock protein binding
FOE78_23460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ