locus-tag	class	description
IDH70_00010	COG0592	DNA-directed DNA polymerase activity
IDH70_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IDH70_00020	COG0187	DNA topoisomerase II activity
IDH70_00025	COG3753	Protein conserved in bacteria
IDH70_00030	COG0561	phosphatase activity
IDH70_00035	COG0823	Involved in the tonB-independent uptake of proteins
IDH70_00040	COG5645	(Lipo)protein
IDH70_00055	COG3977	Valine--pyruvate aminotransferase
IDH70_00080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IDH70_00090	COG1609	Transcriptional regulator
IDH70_00095	COG2885	chlorophyll binding
IDH70_00100	COG2818	Glycosylase
IDH70_00115	COG1484	DNA-dependent DNA replication
IDH70_00125	COG3781	membrane
IDH70_00140	COG2186	Transcriptional regulator
IDH70_00165	COG1815	bacterial-type flagellum-dependent cell motility
IDH70_00170	COG1558	bacterial-type flagellum-dependent cell motility
IDH70_00185	COG4787	bacterial-type flagellum-dependent cell motility
IDH70_00215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IDH70_00220	COG0840	transmembrane signaling receptor activity
IDH70_00245	COG1360	Flagellar Motor Protein
IDH70_00250	COG2198	Histidine kinase
IDH70_00250	COG0643	Histidine kinase
IDH70_00255	COG0835	chemotaxis
IDH70_00285	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IDH70_00300	COG0745	RESPONSE REGULATOR receiver
IDH70_00305	COG2201	protein-glutamate methylesterase activity
IDH70_00310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IDH70_00315	COG1677	Flagellar hook-basal body complex protein FliE
IDH70_00320	COG1766	The M ring may be actively involved in energy transduction
IDH70_00325	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IDH70_00330	COG1317	bacterial-type flagellum organization
IDH70_00335	COG1157	protein secretion by the type III secretion system
IDH70_00345	COG3144	bacterial-type flagellum assembly
IDH70_00360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IDH70_00365	COG3190	flagellar
IDH70_00385	COG2223	nitrite transmembrane transporter activity
IDH70_00395	COG1609	Transcriptional regulator
IDH70_00405	COG1263	PTS System
IDH70_00405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDH70_00425	COG1609	Transcriptional regulator
IDH70_00425	COG2207	Transcriptional regulator
IDH70_00430	COG4214	carbohydrate transport
IDH70_00440	COG4213	ABC transporter substrate-binding protein
IDH70_00450	COG1070	Carbohydrate kinase
IDH70_00455	COG3274	enterobacterial common antigen metabolic process
IDH70_00465	COG0751	glycine-tRNA ligase activity
IDH70_00475	COG0625	glutathione transferase activity
IDH70_00485	COG2864	formate dehydrogenase
IDH70_00490	COG0437	4 iron, 4 sulfur cluster binding
IDH70_00495	COG3383	formate dehydrogenase (NAD+) activity
IDH70_00495	COG0243	molybdopterin cofactor binding
IDH70_00505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IDH70_00510	COG2990	Protein conserved in bacteria
IDH70_00520	COG3722	fumarate hydratase activity
IDH70_00525	COG0246	Mannitol dehydrogenase
IDH70_00530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IDH70_00530	COG2213	PTS system mannitol-specific
IDH70_00540	COG2944	sequence-specific DNA binding
IDH70_00555	COG1846	Transcriptional regulator
IDH70_00560	COG1764	response to oxidative stress
IDH70_00565	COG2194	sulfuric ester hydrolase activity
IDH70_00575	COG0747	negative chemotaxis
IDH70_00580	COG0601	transmembrane transport
IDH70_00585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IDH70_00590	COG0444	Belongs to the ABC transporter superfamily
IDH70_00595	COG4608	Belongs to the ABC transporter superfamily
IDH70_00600	COG2194	sulfuric ester hydrolase activity
IDH70_00620	COG1192	Involved in chromosome partitioning
IDH70_00625	COG1215	transferase activity, transferring glycosyl groups
IDH70_00630	COG1215	transferase activity, transferring glycosyl groups
IDH70_00635	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IDH70_00640	COG0457	Tetratricopeptide repeat
IDH70_00640	COG3118	belongs to the thioredoxin family
IDH70_00645	COG2200	EAL domain
IDH70_00645	COG2199	diguanylate cyclase activity
IDH70_00660	COG0612	Peptidase, M16
IDH70_00670	COG0625	glutathione transferase activity
IDH70_00675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IDH70_00680	COG2200	EAL domain
IDH70_00685	COG2982	Protein involved in outer membrane biogenesis
IDH70_00715	COG0477	Major facilitator Superfamily
IDH70_00720	COG1295	ribonuclease BN
IDH70_00725	COG0583	DNA-binding transcription factor activity
IDH70_00730	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_00735	COG0384	phenazine biosynthesis protein PhzF
IDH70_00740	COG0625	glutathione transferase activity
IDH70_00745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IDH70_00755	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IDH70_00785	COG0596	Alpha beta hydrolase
IDH70_00795	COG3685	Protein conserved in bacteria
IDH70_00800	COG3729	General stress protein
IDH70_00815	COG1263	PTS System
IDH70_00815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDH70_00825	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IDH70_00835	COG0400	carboxylic ester hydrolase activity
IDH70_00840	COG1132	(ABC) transporter
IDH70_00860	COG4774	siderophore transport
IDH70_00880	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IDH70_00885	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IDH70_00890	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IDH70_00895	COG2205	protein histidine kinase activity
IDH70_00900	COG2862	Uncharacterized protein family, UPF0114
IDH70_00935	COG1064	alcohol dehydrogenase
IDH70_00940	COG3387	PFAM Glycoside hydrolase 15-related
IDH70_00950	COG3188	usher protein
IDH70_00980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IDH70_00985	COG1690	Belongs to the RtcB family
IDH70_00990	COG4650	regulator
IDH70_00995	COG1234	tRNA 3'-trailer cleavage
IDH70_01010	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IDH70_01020	COG0339	signal peptide processing
IDH70_01025	COG0742	ribosomal rna small subunit methyltransferase
IDH70_01040	COG0306	phosphate transporter
IDH70_01045	COG2081	HI0933 family
IDH70_01050	COG3710	Transcriptional regulator
IDH70_01060	COG1063	alcohol dehydrogenase
IDH70_01065	COG1546	Belongs to the CinA family
IDH70_01070	COG3468	outer membrane autotransporter barrel domain protein
IDH70_01075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IDH70_01115	COG3706	GGDEF domain
IDH70_01120	COG0113	porphobilinogen synthase activity
IDH70_01125	COG0071	Belongs to the small heat shock protein (HSP20) family
IDH70_01150	COG2186	Transcriptional regulator
IDH70_01155	COG0628	permease
IDH70_01175	COG3718	enzyme involved in inositol metabolism
IDH70_01185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IDH70_01195	COG3962	Belongs to the TPP enzyme family
IDH70_01200	COG0673	inositol 2-dehydrogenase activity
IDH70_01205	COG1082	Xylose isomerase domain protein TIM barrel
IDH70_01210	COG1082	Xylose isomerase domain protein TIM barrel
IDH70_01220	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IDH70_01225	COG0425	Belongs to the sulfur carrier protein TusA family
IDH70_01230	COG3714	YhhN family
IDH70_01240	COG3776	membrane
IDH70_01245	COG0742	ribosomal rna small subunit methyltransferase
IDH70_01250	COG0552	protein localization to endoplasmic reticulum
IDH70_01250	COG0552	protein localization to endoplasmic reticulum
IDH70_01255	COG2884	Cell division ATP-binding protein ftsE
IDH70_01260	COG2177	Part of the ABC transporter FtsEX involved in
IDH70_01265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IDH70_01275	COG0683	leucine binding
IDH70_01285	COG4177	L-phenylalanine transmembrane transporter activity
IDH70_01320	COG0584	glycerophosphoryl diester phosphodiesterase
IDH70_01330	COG0405	Gamma-glutamyltransferase
IDH70_01335	COG1247	-acetyltransferase
IDH70_01345	COG1741	Belongs to the pirin family
IDH70_01350	COG1609	Transcriptional regulator
IDH70_01355	COG3265	gluconokinase activity
IDH70_01360	COG2610	gluconate transmembrane transporter activity
IDH70_01365	COG2095	MarC family integral membrane protein
IDH70_01370	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IDH70_01380	COG1523	belongs to the glycosyl hydrolase 13 family
IDH70_01390	COG0297	glycogen (starch) synthase activity
IDH70_01395	COG0058	SHG alpha-glucan phosphorylase activity
IDH70_01400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IDH70_01415	COG1349	DNA-binding transcription factor activity
IDH70_01420	COG2909	trisaccharide binding
IDH70_01425	COG0058	SHG alpha-glucan phosphorylase activity
IDH70_01430	COG1640	4-alpha-glucanotransferase
IDH70_01435	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IDH70_01435	COG0316	Belongs to the HesB IscA family
IDH70_01440	COG1040	competence protein
IDH70_01455	COG0366	Alpha amylase catalytic
IDH70_01465	COG1918	ferrous iron import across plasma membrane
IDH70_01470	COG2183	response to ionizing radiation
IDH70_01475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IDH70_01490	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IDH70_01495	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IDH70_01500	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IDH70_01505	COG1011	Hydrolase
IDH70_01515	COG0494	nUDIX hydrolase
IDH70_01520	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IDH70_01545	COG4796	Type ii and iii secretion system protein
IDH70_01550	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IDH70_01555	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IDH70_01570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IDH70_01575	COG0546	phosphoglycolate phosphatase activity
IDH70_01580	COG0180	Tryptophanyl-tRNA synthetase
IDH70_01595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IDH70_01600	COG0402	S-adenosylhomocysteine deaminase activity
IDH70_01605	COG0738	Major facilitator superfamily
IDH70_01620	COG2184	nucleotidyltransferase activity
IDH70_01630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IDH70_01635	COG1289	transmembrane transporter activity
IDH70_01640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IDH70_01645	COG1765	OsmC-like protein
IDH70_01650	COG3954	Phosphoribulokinase
IDH70_01655	COG3089	Belongs to the UPF0270 family
IDH70_01660	COG0429	hydrolase of the alpha beta-hydrolase fold
IDH70_01670	COG1609	Transcriptional regulator
IDH70_01675	COG4521	taurine ABC transporter
IDH70_01680	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IDH70_01685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IDH70_01690	COG2175	clavaminate synthase activity
IDH70_01695	COG2200	EAL domain
IDH70_01695	COG2199	diguanylate cyclase activity
IDH70_01700	COG0488	(ABC) transporter
IDH70_01705	COG2249	NAD(P)H dehydrogenase (quinone) activity
IDH70_01710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IDH70_01710	COG0475	glutathione-regulated potassium exporter activity
IDH70_01715	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IDH70_01720	COG1047	Peptidyl-prolyl cis-trans
IDH70_01725	COG2900	Belongs to the SlyX family
IDH70_01730	COG0545	Peptidyl-prolyl cis-trans isomerase
IDH70_01735	COG2964	Protein conserved in bacteria
IDH70_01745	COG2923	Belongs to the DsrF TusC family
IDH70_01750	COG2168	tRNA wobble position uridine thiolation
IDH70_01755	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IDH70_01760	COG0049	tRNA binding
IDH70_01780	COG2193	ferroxidase activity
IDH70_01790	COG0051	transcription antitermination factor activity, RNA binding
IDH70_01800	COG0088	Forms part of the polypeptide exit tunnel
IDH70_01815	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IDH70_01830	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IDH70_01875	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IDH70_01885	COG1841	ribosomal large subunit assembly
IDH70_01890	COG0200	Binds to the 23S rRNA
IDH70_01895	COG0201	protein transport
IDH70_01900	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IDH70_01910	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IDH70_01915	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IDH70_01925	COG0203	ribosomal protein L17
IDH70_01935	COG3036	rescue of stalled ribosome
IDH70_01940	COG1970	mechanosensitive ion channel activity
IDH70_01950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IDH70_01950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IDH70_01955	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IDH70_01960	COG0242	peptide deformylase activity
IDH70_01965	COG0758	DNA mediated transformation
IDH70_01975	COG0551	DNA topoisomerase type I activity
IDH70_01980	COG0009	L-threonylcarbamoyladenylate synthase
IDH70_01995	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IDH70_02030	COG1126	abc transporter atp-binding protein
IDH70_02035	COG0765	amino acid transport
IDH70_02040	COG4597	amino acid ABC transporter
IDH70_02045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDH70_02050	COG1560	Kdo2-lipid A biosynthetic process
IDH70_02070	COG2264	protein methyltransferase activity
IDH70_02075	COG4145	pantothenate transmembrane transporter activity
IDH70_02080	COG3924	membrane
IDH70_02085	COG0439	Biotin carboxylase
IDH70_02090	COG0511	ligase activity, forming carbon-carbon bonds
IDH70_02095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IDH70_02100	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
IDH70_02105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IDH70_02110	COG0604	alcohol dehydrogenase
IDH70_02115	COG2200	EAL domain
IDH70_02115	COG2199	diguanylate cyclase activity
IDH70_02120	COG1077	Cell shape determining protein MreB Mrl
IDH70_02125	COG1792	Involved in formation and maintenance of cell shape
IDH70_02130	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IDH70_02140	COG1530	ribonuclease E activity
IDH70_02145	COG3164	Protein of unknown function
IDH70_02150	COG0312	modulator of DNA gyrase
IDH70_02155	COG0583	DNA-binding transcription factor activity
IDH70_02165	COG1566	PFAM secretion protein HlyD family protein
IDH70_02170	COG1289	transmembrane transporter activity
IDH70_02180	COG2732	(Barnase) inhibitor
IDH70_02200	COG1438	arginine binding
IDH70_02210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IDH70_02215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IDH70_02220	COG3105	Protein conserved in bacteria
IDH70_02225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IDH70_02230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IDH70_02235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IDH70_02240	COG0625	glutathione transferase activity
IDH70_02245	COG2969	positive regulation of protein catabolic process
IDH70_02250	COG0493	'glutamate synthase
IDH70_02255	COG0069	glutamate synthase activity
IDH70_02255	COG0067	glutamate synthase
IDH70_02255	COG0070	glutamate synthase
IDH70_02260	COG0784	Response regulator, receiver
IDH70_02260	COG2198	Histidine kinase
IDH70_02260	COG5002	protein histidine kinase activity
IDH70_02270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IDH70_02275	COG1660	Displays ATPase and GTPase activities
IDH70_02290	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IDH70_02295	COG1137	ATPase activity
IDH70_02300	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IDH70_02305	COG3117	lipopolysaccharide transmembrane transporter activity
IDH70_02310	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IDH70_02320	COG0530	calcium, potassium:sodium antiporter activity
IDH70_02325	COG1127	ABC transporter
IDH70_02330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IDH70_02335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IDH70_02340	COG2854	intermembrane phospholipid transfer
IDH70_02345	COG3113	response to antibiotic
IDH70_02350	COG5007	Belongs to the BolA IbaG family
IDH70_02355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IDH70_02360	COG3423	Transcriptional regulator
IDH70_02365	COG0142	geranyltranstransferase activity
IDH70_02370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IDH70_02375	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IDH70_02380	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IDH70_02385	COG0642	Histidine kinase
IDH70_02390	COG0745	RESPONSE REGULATOR receiver
IDH70_02395	COG2027	D-alanyl-D-alanine carboxypeptidase
IDH70_02405	COG1534	Rna-binding protein
IDH70_02410	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IDH70_02420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IDH70_02425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IDH70_02430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IDH70_02450	COG0195	Participates in both transcription termination and antitermination
IDH70_02460	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IDH70_02465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IDH70_02470	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IDH70_02485	COG0513	Belongs to the DEAD box helicase family
IDH70_02490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IDH70_02495	COG0826	peptidase U32
IDH70_02500	COG0826	peptidase U32
IDH70_02505	COG3154	lipid carrier protein
IDH70_02510	COG3153	acetyltransferase
IDH70_02515	COG2827	Endonuclease containing a URI domain
IDH70_02525	COG0693	protein deglycase activity
IDH70_02530	COG0702	epimerase
IDH70_02535	COG0602	queuosine metabolic process
IDH70_02555	COG1447	Phosphotransferase system cellobiose-specific component IIA
IDH70_02560	COG1486	melibiose metabolic process
IDH70_02565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IDH70_02570	COG0366	Alpha amylase catalytic
IDH70_02575	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IDH70_02585	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IDH70_02590	COG0540	Belongs to the ATCase OTCase family
IDH70_02600	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IDH70_02635	COG2927	DNA polymerase III (CHI subunit)
IDH70_02640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IDH70_02645	COG0795	lipopolysaccharide-transporting ATPase activity
IDH70_02650	COG0795	lipopolysaccharide-transporting ATPase activity
IDH70_02665	COG2733	membrane
IDH70_02670	COG3710	Transcriptional regulator
IDH70_02675	COG3539	Fimbrial protein
IDH70_02680	COG3121	Chaperone
IDH70_02705	COG0582	viral genome integration into host DNA
IDH70_02780	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IDH70_02785	COG3318	Belongs to the UPF0149 family
IDH70_02785	COG3012	SEC-C Motif Domain Protein
IDH70_02790	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IDH70_02830	COG1609	Transcriptional regulator
IDH70_02835	COG1263	PTS System
IDH70_02835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDH70_02840	COG2723	6-phospho-beta-galactosidase activity
IDH70_02850	COG2211	Major facilitator Superfamily
IDH70_02855	COG1472	Belongs to the glycosyl hydrolase 3 family
IDH70_02860	COG2197	response regulator
IDH70_02915	COG4794	Type iii secretion
IDH70_02925	COG4792	protein secretion
IDH70_02965	COG4669	(LipO)protein
IDH70_03000	COG3933	PFAM sigma-54 factor interaction domain-containing protein
IDH70_03000	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IDH70_03015	COG3715	PTS system
IDH70_03020	COG3716	PTS system mannose fructose sorbose family IID component
IDH70_03025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IDH70_03035	COG2226	methyltransferase
IDH70_03045	COG5455	response to cobalt ion
IDH70_03055	COG0673	inositol 2-dehydrogenase activity
IDH70_03060	COG1126	abc transporter atp-binding protein
IDH70_03065	COG0765	amino acid transport
IDH70_03075	COG1609	Transcriptional regulator
IDH70_03085	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IDH70_03090	COG1942	4-Oxalocrotonate Tautomerase
IDH70_03100	COG0840	transmembrane signaling receptor activity
IDH70_03115	COG0671	phosphoesterase, PA-phosphatase related
IDH70_03130	COG0442	prolyl-tRNA aminoacylation
IDH70_03135	COG4114	ferric iron reductase
IDH70_03140	COG3706	GGDEF domain
IDH70_03165	COG2813	Specifically methylates the guanine in position
IDH70_03170	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
IDH70_03175	COG0456	acetyltransferase
IDH70_03180	COG1011	Hydrolase
IDH70_03305	COG0515	serine threonine protein kinase
IDH70_03365	COG1397	ADP-ribosylglycohydrolase
IDH70_03390	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IDH70_03395	COG2823	Periplasmic or secreted lipoprotein
IDH70_03400	COG5487	UPF0391 membrane protein
IDH70_03410	COG4667	esterase of the alpha-beta hydrolase superfamily
IDH70_03415	COG0084	hydrolase, TatD family'
IDH70_03430	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IDH70_03435	COG0813	purine-nucleoside phosphorylase activity
IDH70_03440	COG3726	membrane protein affecting hemolysin expression
IDH70_03445	COG0560	Phosphoserine phosphatase
IDH70_03450	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IDH70_03475	COG0488	(ABC) transporter
IDH70_03480	COG1349	DNA-binding transcription factor activity
IDH70_03485	COG0741	lytic transglycosylase activity
IDH70_03490	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
IDH70_03495	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
IDH70_03500	COG0406	alpha-ribazole phosphatase activity
IDH70_03505	COG2207	Transcriptional regulator
IDH70_03505	COG3708	Transcriptional regulator
IDH70_03510	COG3045	CreA protein
IDH70_03515	COG0745	RESPONSE REGULATOR receiver
IDH70_03520	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IDH70_03530	COG0527	aspartate kinase activity
IDH70_03530	COG0460	homoserine dehydrogenase
IDH70_03555	COG0521	Mo-molybdopterin cofactor biosynthetic process
IDH70_03565	COG1584	GPR1 FUN34 yaaH family protein
IDH70_03585	COG0583	DNA-binding transcription factor activity
IDH70_03600	COG0196	riboflavin kinase activity
IDH70_03605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IDH70_03610	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IDH70_03615	COG1047	Peptidyl-prolyl cis-trans
IDH70_03620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IDH70_03625	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IDH70_03630	COG0505	Belongs to the CarA family
IDH70_03660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IDH70_03670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IDH70_03675	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IDH70_03690	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IDH70_03700	COG0564	pseudouridine synthase activity
IDH70_03705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IDH70_03710	COG0417	DNA replication proofreading
IDH70_03725	COG0586	Pfam SNARE associated Golgi protein
IDH70_03735	COG1178	ABC-type Fe3 transport system permease component
IDH70_03745	COG4533	DNA binding
IDH70_03750	COG2814	Major facilitator Superfamily
IDH70_03755	COG0066	3-isopropylmalate dehydratase activity
IDH70_03760	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IDH70_03770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IDH70_03780	COG0028	Belongs to the TPP enzyme family
IDH70_03795	COG2001	Belongs to the MraZ family
IDH70_03800	COG0275	rRNA processing
IDH70_03805	COG3116	cell division
IDH70_03810	COG0768	penicillin binding
IDH70_03815	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IDH70_03820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IDH70_03825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IDH70_03835	COG0772	Belongs to the SEDS family
IDH70_03840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IDH70_03845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IDH70_03850	COG1181	Belongs to the D-alanine--D-alanine ligase family
IDH70_03860	COG0849	cell division
IDH70_03865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IDH70_03890	COG3157	Type VI secretion system effector, Hcp
IDH70_03900	COG0494	nUDIX hydrolase
IDH70_03910	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IDH70_03920	COG0516	GMP reductase activity
IDH70_03925	COG1459	type II secretion system
IDH70_03930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IDH70_03935	COG4969	Belongs to the N-Me-Phe pilin family
IDH70_03945	COG3023	N-Acetylmuramoyl-L-alanine amidase
IDH70_03950	COG3725	Membrane protein required for beta-lactamase induction
IDH70_03955	COG3940	Belongs to the glycosyl hydrolase 43 family
IDH70_03960	COG2211	Major facilitator Superfamily
IDH70_03970	COG2186	Transcriptional regulator
IDH70_03975	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IDH70_03980	COG0508	dehydrogenase complex catalyzes the overall conversion of
IDH70_03985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IDH70_03990	COG0840	transmembrane signaling receptor activity
IDH70_03995	COG3479	Phenolic acid decarboxylase
IDH70_04010	COG3468	outer membrane autotransporter barrel domain protein
IDH70_04010	COG3210	domain, Protein
IDH70_04020	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_04025	COG2731	YhcH YjgK YiaL family protein
IDH70_04040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IDH70_04055	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IDH70_04060	COG1349	DNA-binding transcription factor activity
IDH70_04070	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IDH70_04085	COG2132	Multicopper oxidase
IDH70_04095	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IDH70_04100	COG0288	reversible hydration of carbon dioxide
IDH70_04105	COG1131	(ABC) transporter
IDH70_04110	COG0842	Transport permease protein
IDH70_04130	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IDH70_04135	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IDH70_04140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IDH70_04145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IDH70_04160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IDH70_04165	COG1489	DNA binding
IDH70_04170	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IDH70_04175	COG1643	Atp-dependent helicase
IDH70_04180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IDH70_04185	COG4774	siderophore transport
IDH70_04190	COG1120	ATPase activity
IDH70_04195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IDH70_04200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IDH70_04215	COG0316	Belongs to the HesB IscA family
IDH70_04220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IDH70_04225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IDH70_04230	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IDH70_04240	COG3835	regulator
IDH70_04255	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IDH70_04270	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IDH70_04275	COG0528	UMP kinase activity
IDH70_04285	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IDH70_04290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IDH70_04295	COG0575	Belongs to the CDS family
IDH70_04305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IDH70_04310	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IDH70_04315	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IDH70_04320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IDH70_04330	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IDH70_04335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IDH70_04340	COG0587	DNA-directed DNA polymerase activity
IDH70_04345	COG0825	malonyl-CoA metabolic process
IDH70_04350	COG1982	Orn Lys Arg decarboxylase major
IDH70_04355	COG0346	lactoylglutathione lyase activity
IDH70_04360	COG0037	tRNA processing
IDH70_04370	COG4568	rho-dependent transcription termination
IDH70_04380	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IDH70_04390	COG1720	tRNA m6t6A37 methyltransferase activity
IDH70_04405	COG2011	ABC-type metal ion transport system permease component
IDH70_04415	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IDH70_04450	COG0583	DNA-binding transcription factor activity
IDH70_04455	COG3021	interspecies interaction between organisms
IDH70_04460	COG0741	lytic transglycosylase activity
IDH70_04460	COG1388	LysM domain
IDH70_04465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IDH70_04470	COG2226	methyltransferase
IDH70_04480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IDH70_04490	COG1953	Uracil, thiamine, allantoin
IDH70_04545	COG0765	amino acid transport
IDH70_04550	COG1126	abc transporter atp-binding protein
IDH70_04555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IDH70_04570	COG2351	hydroxyisourate hydrolase activity
IDH70_04575	COG2233	PERMEase
IDH70_04580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IDH70_04585	COG0436	Aminotransferase
IDH70_04595	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
IDH70_04600	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IDH70_04610	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IDH70_04625	COG1518	maintenance of DNA repeat elements
IDH70_04630	COG1203	CRISPR-associated helicase, Cas3
IDH70_04655	COG1960	acyl-CoA dehydrogenase activity
IDH70_04660	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IDH70_04665	COG0121	glutamine amidotransferase
IDH70_04670	COG3034	peptidoglycan biosynthetic process
IDH70_04685	COG1172	Belongs to the binding-protein-dependent transport system permease family
IDH70_04690	COG1129	ABC transporter
IDH70_04695	COG2195	Cleaves the N-terminal amino acid of tripeptides
IDH70_04700	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IDH70_04705	COG1073	alpha beta
IDH70_04720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IDH70_04725	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IDH70_04735	COG0582	viral genome integration into host DNA
IDH70_05020	COG1196	nuclear chromosome segregation
IDH70_05075	COG0667	Aldo Keto reductase
IDH70_05095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IDH70_05100	COG1349	DNA-binding transcription factor activity
IDH70_05110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IDH70_05115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IDH70_05120	COG1882	Formate acetyltransferase
IDH70_05130	COG1121	(ABC) transporter
IDH70_05135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IDH70_05140	COG0803	Belongs to the bacterial solute-binding protein 9 family
IDH70_05145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDH70_05145	COG1263	PTS System
IDH70_05145	COG2190	(PTS) system
IDH70_05150	COG1609	Transcriptional regulator
IDH70_05155	COG0598	Magnesium transport protein CorA
IDH70_05175	COG0513	Belongs to the DEAD box helicase family
IDH70_05180	COG3615	Tellurite resistance protein tehB
IDH70_05185	COG4604	ABC transporter, ATP-binding protein
IDH70_05190	COG4605	iron ion homeostasis
IDH70_05200	COG4607	ABC-type enterochelin transport system periplasmic component
IDH70_05210	COG0443	Heat shock 70 kDa protein
IDH70_05215	COG2214	Heat shock protein DnaJ domain protein
IDH70_05235	COG3604	Transcriptional regulator
IDH70_05240	COG2211	Major facilitator Superfamily
IDH70_05255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IDH70_05275	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IDH70_05280	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_05285	COG0561	phosphatase activity
IDH70_05290	COG1733	regulation of RNA biosynthetic process
IDH70_05295	COG1064	alcohol dehydrogenase
IDH70_05300	COG2155	Conserved Protein
IDH70_05310	COG1012	belongs to the aldehyde dehydrogenase family
IDH70_05315	COG2194	sulfuric ester hydrolase activity
IDH70_05355	COG0444	Belongs to the ABC transporter superfamily
IDH70_05360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IDH70_05365	COG0601	transmembrane transport
IDH70_05370	COG0747	negative chemotaxis
IDH70_05380	COG5001	Diguanylate cyclase
IDH70_05390	COG0456	acetyltransferase
IDH70_05405	COG1278	Cold shock
IDH70_05410	COG3729	General stress protein
IDH70_05420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IDH70_05430	COG2323	membrane
IDH70_05440	COG3416	Protein conserved in bacteria
IDH70_05445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IDH70_05455	COG4126	flavin adenine dinucleotide binding
IDH70_05465	COG2974	May be involved in recombination
IDH70_05470	COG1940	carbohydrate kinase activity
IDH70_05480	COG0419	ATPase involved in DNA repair
IDH70_05485	COG0420	3'-5' exonuclease activity
IDH70_05490	COG0745	RESPONSE REGULATOR receiver
IDH70_05505	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IDH70_05525	COG0668	transmembrane transport
IDH70_05530	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
IDH70_05545	COG1862	Preprotein translocase
IDH70_05550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IDH70_05555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IDH70_05560	COG4238	major outer membrane lipoprotein
IDH70_05565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IDH70_05570	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IDH70_05570	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IDH70_05575	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IDH70_05580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IDH70_05585	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IDH70_05590	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IDH70_05595	COG0596	Alpha beta hydrolase
IDH70_05605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IDH70_05610	COG0142	geranyltranstransferase activity
IDH70_05620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IDH70_05620	COG0301	tRNA thio-modification
IDH70_05630	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IDH70_05635	COG1666	GTP binding
IDH70_05640	COG2814	Major facilitator Superfamily
IDH70_05645	COG0109	protoheme IX farnesyltransferase activity
IDH70_05650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IDH70_05655	COG1845	cytochrome c oxidase, subunit III
IDH70_05660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IDH70_05665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IDH70_05670	COG2223	nitrite transmembrane transporter activity
IDH70_05675	COG3056	Lipoprotein
IDH70_05680	COG0271	Belongs to the BolA IbaG family
IDH70_05705	COG0776	regulation of translation
IDH70_05710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IDH70_05715	COG1555	photosystem II stabilization
IDH70_05720	COG0824	Thioesterase
IDH70_05735	COG1522	sequence-specific DNA binding
IDH70_05740	COG1132	(ABC) transporter
IDH70_05745	COG1132	(ABC) transporter
IDH70_05750	COG0347	Belongs to the P(II) protein family
IDH70_05755	COG0004	ammonium transporteR
IDH70_05760	COG1946	Acyl-CoA thioesterase
IDH70_05765	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IDH70_05770	COG3695	enzyme binding
IDH70_05795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IDH70_05800	COG0254	rRNA binding
IDH70_05805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IDH70_05810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IDH70_05815	COG1309	transcriptional regulator
IDH70_05830	COG2832	Protein of unknown function (DUF454)
IDH70_05835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IDH70_05845	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IDH70_05850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IDH70_05860	COG0563	adenylate kinase activity
IDH70_05865	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IDH70_05870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IDH70_05875	COG4651	solute:proton antiporter activity
IDH70_05875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IDH70_05880	COG0737	Belongs to the 5'-nucleotidase family
IDH70_05890	COG0583	DNA-binding transcription factor activity
IDH70_05900	COG3735	TraB family
IDH70_05905	COG2217	Heavy metal translocating P-type atpase
IDH70_05915	COG1585	Membrane protein implicated in regulation of membrane protease activity
IDH70_05920	COG0330	HflC and HflK could
IDH70_05925	COG3118	belongs to the thioredoxin family
IDH70_05930	COG0300	oxidoreductase activity
IDH70_05935	COG2755	lipolytic protein G-D-S-L family
IDH70_05940	COG4181	ATPase activity
IDH70_05945	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IDH70_05950	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IDH70_05955	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IDH70_05965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IDH70_05970	COG0215	cysteine-tRNA ligase activity
IDH70_05975	COG1349	DNA-binding transcription factor activity
IDH70_05980	COG0673	inositol 2-dehydrogenase activity
IDH70_05985	COG2501	S4 domain
IDH70_06010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IDH70_06020	COG0561	phosphatase activity
IDH70_06025	COG1454	alcohol dehydrogenase
IDH70_06030	COG2610	gluconate transmembrane transporter activity
IDH70_06050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IDH70_06055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IDH70_06065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IDH70_06070	COG0321	lipoyl(octanoyl) transferase activity
IDH70_06080	COG1686	Belongs to the peptidase S11 family
IDH70_06085	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IDH70_06090	COG0772	Belongs to the SEDS family
IDH70_06095	COG0768	penicillin binding
IDH70_06100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IDH70_06105	COG0799	negative regulation of ribosome biogenesis
IDH70_06115	COG1466	dna polymerase III delta subunit
IDH70_06120	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
IDH70_06125	COG0495	leucyl-tRNA aminoacylation
IDH70_06130	COG2888	peptidyl-tyrosine sulfation
IDH70_06135	COG1126	abc transporter atp-binding protein
IDH70_06140	COG0765	amino acid transport
IDH70_06145	COG0765	amino acid transport
IDH70_06155	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IDH70_06165	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IDH70_06170	COG1702	phosphate starvation-inducible protein PhoH
IDH70_06180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IDH70_06220	COG0367	asparagine synthase
IDH70_06225	COG1846	Transcriptional regulator
IDH70_06225	COG1940	carbohydrate kinase activity
IDH70_06230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IDH70_06240	COG2190	(PTS) system
IDH70_06240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDH70_06240	COG1263	PTS System
IDH70_06245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IDH70_06250	COG0814	amino acid
IDH70_06265	COG0735	belongs to the Fur family
IDH70_06280	COG0596	Alpha beta hydrolase
IDH70_06285	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IDH70_06290	COG0033	Phosphoglucomutase
IDH70_06295	COG0745	RESPONSE REGULATOR receiver
IDH70_06305	COG3272	Protein of unknown function (DUF1722)
IDH70_06320	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IDH70_06325	COG1984	allophanate hydrolase subunit 2
IDH70_06345	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IDH70_06355	COG0372	Belongs to the citrate synthase family
IDH70_06360	COG2009	succinate dehydrogenase
IDH70_06365	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IDH70_06370	COG1053	succinate dehydrogenase
IDH70_06375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IDH70_06380	COG0567	Dehydrogenase, E1 component
IDH70_06385	COG0508	dehydrogenase complex catalyzes the overall conversion of
IDH70_06390	COG0045	succinate-CoA ligase (ADP-forming) activity
IDH70_06395	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IDH70_06400	COG1271	oxidase subunit
IDH70_06405	COG1294	oxidase, subunit
IDH70_06410	COG4890	Cyd operon protein YbgT
IDH70_06415	COG3790	cyd operon protein YbgE
IDH70_06420	COG0824	Thioesterase
IDH70_06425	COG0811	peptide transport
IDH70_06430	COG0848	biopolymer transport protein
IDH70_06435	COG3064	Membrane
IDH70_06440	COG0823	Involved in the tonB-independent uptake of proteins
IDH70_06445	COG2885	chlorophyll binding
IDH70_06450	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IDH70_06495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IDH70_06500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IDH70_06510	COG1230	cation diffusion facilitator family transporter
IDH70_06515	COG0784	Response regulator, receiver
IDH70_06515	COG2198	Histidine kinase
IDH70_06515	COG5002	protein histidine kinase activity
IDH70_06530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IDH70_06535	COG0588	phosphoglycerate mutase activity
IDH70_06540	COG2017	converts alpha-aldose to the beta-anomer
IDH70_06550	COG1085	galactose-1-phosphate uridylyltransferase
IDH70_06555	COG1119	ATPase activity
IDH70_06560	COG3585	molybdate ion transport
IDH70_06560	COG2005	Transcriptional regulator
IDH70_06570	COG0725	ABC transporter, periplasmic molybdate-binding protein
IDH70_06575	COG4149	molybdate abc transporter
IDH70_06585	COG0561	phosphatase activity
IDH70_06590	COG2706	6-phosphogluconolactonase activity
IDH70_06605	COG1881	PFAM PEBP family protein
IDH70_06615	COG2130	NADP-dependent
IDH70_06625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IDH70_06630	COG0156	8-amino-7-oxononanoate synthase activity
IDH70_06665	COG0521	Mo-molybdopterin cofactor biosynthetic process
IDH70_06670	COG0315	cyclic pyranopterin monophosphate synthase activity
IDH70_06675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IDH70_06695	COG0840	transmembrane signaling receptor activity
IDH70_06700	COG0670	Belongs to the BI1 family
IDH70_06705	COG0392	lysyltransferase activity
IDH70_06710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IDH70_06715	COG3568	Endonuclease Exonuclease Phosphatase
IDH70_06725	COG0513	Belongs to the DEAD box helicase family
IDH70_06730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IDH70_06735	COG0477	Major facilitator Superfamily
IDH70_06740	COG0306	phosphate transporter
IDH70_06745	COG1376	ErfK ybiS ycfS ynhG family protein
IDH70_06750	COG3387	PFAM Glycoside hydrolase 15-related
IDH70_06755	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_06760	COG4619	ABC transporter
IDH70_06765	COG0390	transport system, permease component
IDH70_06770	COG0586	Pfam SNARE associated Golgi protein
IDH70_06780	COG1686	Belongs to the peptidase S11 family
IDH70_06790	COG3264	Mechanosensitive ion channel
IDH70_06790	COG1511	domain protein
IDH70_06795	COG0277	FAD linked oxidase domain protein
IDH70_06800	COG1472	Belongs to the glycosyl hydrolase 3 family
IDH70_06810	COG5001	Diguanylate cyclase
IDH70_06830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IDH70_06835	COG1609	Transcriptional regulator
IDH70_06840	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_06845	COG3265	gluconokinase activity
IDH70_06875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IDH70_06890	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_06895	COG3685	Protein conserved in bacteria
IDH70_06915	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IDH70_06920	COG0477	Major facilitator Superfamily
IDH70_06925	COG1732	Glycine betaine
IDH70_06930	COG1174	glycine betaine transport
IDH70_06935	COG1125	glycine betaine transport
IDH70_06940	COG1174	glycine betaine transport
IDH70_06945	COG0789	Transcriptional regulator
IDH70_06965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IDH70_06970	COG1473	amidohydrolase
IDH70_06975	COG0667	Aldo Keto reductase
IDH70_06980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IDH70_06985	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
IDH70_06990	COG0668	transmembrane transport
IDH70_06995	COG1126	abc transporter atp-binding protein
IDH70_07000	COG0765	amino acid transport
IDH70_07005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDH70_07010	COG0783	Belongs to the Dps family
IDH70_07020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IDH70_07030	COG1321	iron dependent repressor
IDH70_07035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IDH70_07040	COG1566	PFAM secretion protein HlyD family protein
IDH70_07045	COG2814	Major facilitator Superfamily
IDH70_07055	COG2814	Major facilitator Superfamily
IDH70_07060	COG0488	(ABC) transporter
IDH70_07065	COG3706	GGDEF domain
IDH70_07065	COG2203	Gaf domain
IDH70_07065	COG5001	Diguanylate cyclase
IDH70_07065	COG4251	negative regulation of phosphorylation
IDH70_07070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IDH70_07080	COG1446	asparaginase
IDH70_07085	COG4172	Belongs to the ABC transporter superfamily
IDH70_07090	COG0747	negative chemotaxis
IDH70_07095	COG0601	transmembrane transport
IDH70_07120	COG0673	inositol 2-dehydrogenase activity
IDH70_07130	COG2133	pyrroloquinoline quinone binding
IDH70_07140	COG1686	Belongs to the peptidase S11 family
IDH70_07145	COG0814	amino acid
IDH70_07150	COG0671	phosphoesterase, PA-phosphatase related
IDH70_07180	COG0778	Nitroreductase
IDH70_07195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IDH70_07200	COG3842	ATPase activity
IDH70_07205	COG1176	ABC-type spermidine putrescine transport system, permease component I
IDH70_07210	COG1177	transmembrane transport
IDH70_07225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDH70_07230	COG4160	amino acid transport
IDH70_07235	COG4215	(ABC) transporter
IDH70_07240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDH70_07245	COG1126	abc transporter atp-binding protein
IDH70_07255	COG0393	Putative heavy-metal-binding
IDH70_07260	COG3023	N-Acetylmuramoyl-L-alanine amidase
IDH70_07265	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IDH70_07270	COG0028	Belongs to the TPP enzyme family
IDH70_07275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IDH70_07285	COG2431	L-lysine efflux transmembrane transporter activity
IDH70_07290	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
IDH70_07295	COG1278	Cold shock
IDH70_07300	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IDH70_07305	COG0542	response to heat
IDH70_07310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IDH70_07315	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IDH70_07320	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IDH70_07325	COG4988	ABC transporter
IDH70_07330	COG0492	ferredoxin-NADP+ reductase activity
IDH70_07340	COG1674	ftsk spoiiie
IDH70_07340	COG3107	peptidoglycan biosynthetic process
IDH70_07345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IDH70_07350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IDH70_07355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IDH70_07360	COG0477	Major facilitator Superfamily
IDH70_07365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IDH70_07370	COG1882	Formate acetyltransferase
IDH70_07375	COG2116	formate transmembrane transporter activity
IDH70_07380	COG1944	ATP diphosphatase activity
IDH70_07385	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IDH70_07400	COG0539	negative regulation of cytoplasmic translation
IDH70_07410	COG0658	competence protein
IDH70_07410	COG2333	competence protein COMEC
IDH70_07425	COG3214	Protein conserved in bacteria
IDH70_07430	COG2835	tetraacyldisaccharide 4'-kinase activity
IDH70_07435	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IDH70_07440	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IDH70_07445	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IDH70_07450	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
IDH70_07455	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IDH70_07465	COG2989	Protein conserved in bacteria
IDH70_07470	COG3108	Peptidase M15
IDH70_07475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IDH70_07480	COG1448	Aminotransferase
IDH70_07495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IDH70_07500	COG0308	aminopeptidase N
IDH70_07510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IDH70_07520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IDH70_07525	COG0431	NADPH-dependent FMN reductase
IDH70_07530	COG0167	dihydroorotate dehydrogenase activity
IDH70_07540	COG3217	Mosc domain protein beta barrel domain protein
IDH70_07540	COG0633	Ferredoxin
IDH70_07545	COG0116	Belongs to the methyltransferase superfamily
IDH70_07545	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IDH70_07550	COG0488	(ABC) transporter
IDH70_07555	COG2995	paraquat-inducible protein a
IDH70_07560	COG3008	intermembrane lipid transfer
IDH70_07560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IDH70_07565	COG3009	Protein conserved in bacteria
IDH70_07570	COG3130	regulation of translation
IDH70_07575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IDH70_07580	COG1067	ATP-dependent peptidase activity
IDH70_07585	COG3120	sequence-specific DNA binding
IDH70_07600	COG3070	regulator of competence-specific genes
IDH70_07605	COG1289	transmembrane transporter activity
IDH70_07610	COG3304	Inner membrane component domain
IDH70_07615	COG0210	DNA helicase
IDH70_07630	COG1832	CoA-binding protein
IDH70_07640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IDH70_07650	COG2920	part of a sulfur-relay system
IDH70_07655	COG0670	Belongs to the BI1 family
IDH70_07675	COG1012	belongs to the aldehyde dehydrogenase family
IDH70_07695	COG2233	PERMEase
IDH70_07700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IDH70_07705	COG2267	carboxylic ester hydrolase activity
IDH70_07710	COG0251	oxidation-reduction process
IDH70_07725	COG1309	transcriptional regulator
IDH70_07735	COG1113	amino acid transport
IDH70_07745	COG2197	response regulator
IDH70_07755	COG3136	membrane protein required for alginate biosynthesis
IDH70_07765	COG2197	response regulator
IDH70_07775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IDH70_07785	COG3210	domain, Protein
IDH70_07795	COG2831	hemolysin activation secretion protein
IDH70_07800	COG0736	holo-[acyl-carrier-protein] synthase activity
IDH70_07810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IDH70_07815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IDH70_07825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IDH70_07840	COG1136	(ABC) transporter
IDH70_07890	COG0659	secondary active sulfate transmembrane transporter activity
IDH70_07940	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IDH70_07945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IDH70_07965	COG5645	(Lipo)protein
IDH70_07975	COG1560	Kdo2-lipid A biosynthetic process
IDH70_07980	COG1902	pentaerythritol trinitrate reductase activity
IDH70_07985	COG1054	Belongs to the UPF0176 family
IDH70_07990	COG2353	YceI-like domain
IDH70_07995	COG3038	cytochrome b561
IDH70_08000	COG0477	Major facilitator Superfamily
IDH70_08025	COG0418	dihydroorotase activity
IDH70_08035	COG2999	glutathione oxidoreductase activity
IDH70_08045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IDH70_08055	COG0728	peptidoglycan biosynthetic process
IDH70_08060	COG3418	PFAM FlgN family protein
IDH70_08070	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IDH70_08075	COG1815	bacterial-type flagellum-dependent cell motility
IDH70_08080	COG1558	bacterial-type flagellum-dependent cell motility
IDH70_08090	COG1749	Flagellar hook protein flgE
IDH70_08120	COG1256	bacterial-type flagellum assembly
IDH70_08130	COG1530	ribonuclease E activity
IDH70_08135	COG0564	pseudouridine synthase activity
IDH70_08145	COG1399	metal-binding, possibly nucleic acid-binding protein
IDH70_08150	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IDH70_08155	COG0416	fatty acid biosynthetic process
IDH70_08160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IDH70_08165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IDH70_08180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IDH70_08185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IDH70_08190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IDH70_08195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IDH70_08200	COG0470	DNA polymerase III
IDH70_08205	COG0084	hydrolase, TatD family'
IDH70_08210	COG1263	PTS System
IDH70_08210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDH70_08245	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IDH70_08255	COG0537	adenosine 5'-monophosphoramidase activity
IDH70_08260	COG5633	Lipoprotein
IDH70_08265	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
IDH70_08275	COG1472	Belongs to the glycosyl hydrolase 3 family
IDH70_08285	COG1252	NADH dehydrogenase
IDH70_08290	COG3134	Outer membrane lipoprotein
IDH70_08295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IDH70_08305	COG4591	ABC-type transport system involved in lipoprotein release permease component
IDH70_08315	COG4591	ABC-type transport system involved in lipoprotein release permease component
IDH70_08320	COG1940	carbohydrate kinase activity
IDH70_08325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IDH70_08330	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IDH70_08335	COG1177	transmembrane transport
IDH70_08355	COG2850	peptidyl-arginine hydroxylation
IDH70_08360	COG2205	protein histidine kinase activity
IDH70_08370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IDH70_08375	COG2915	High frequency lysogenization protein hflD homolog
IDH70_08395	COG0538	isocitrate dehydrogenase activity
IDH70_08440	COG0456	acetyltransferase
IDH70_08470	COG0583	DNA-binding transcription factor activity
IDH70_08485	COG0814	amino acid
IDH70_08490	COG4251	negative regulation of phosphorylation
IDH70_08490	COG3706	GGDEF domain
IDH70_08490	COG5001	Diguanylate cyclase
IDH70_08490	COG2203	Gaf domain
IDH70_08525	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
IDH70_08535	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_08555	COG0583	DNA-binding transcription factor activity
IDH70_08560	COG1063	alcohol dehydrogenase
IDH70_08565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IDH70_08570	COG0300	oxidoreductase activity
IDH70_08580	COG4993	Dehydrogenase
IDH70_08600	COG0583	DNA-binding transcription factor activity
IDH70_08620	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_08625	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
IDH70_08630	COG1349	DNA-binding transcription factor activity
IDH70_08665	COG1609	Transcriptional regulator
IDH70_08670	COG0477	Major facilitator Superfamily
IDH70_08670	COG2814	Major facilitator Superfamily
IDH70_08675	COG1082	Xylose isomerase domain protein TIM barrel
IDH70_08680	COG0673	inositol 2-dehydrogenase activity
IDH70_08685	COG0604	alcohol dehydrogenase
IDH70_08690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IDH70_08695	COG1309	transcriptional regulator
IDH70_08700	COG1012	belongs to the aldehyde dehydrogenase family
IDH70_08715	COG3546	catalase activity
IDH70_08735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IDH70_08740	COG1280	lysine exporter protein (LysE YggA)
IDH70_08765	COG2011	ABC-type metal ion transport system permease component
IDH70_08775	COG1464	Belongs to the NlpA lipoprotein family
IDH70_08805	COG3729	General stress protein
IDH70_08845	COG1064	alcohol dehydrogenase
IDH70_08850	COG1113	amino acid transport
IDH70_08855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IDH70_08870	COG4977	sequence-specific DNA binding
IDH70_08875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IDH70_08880	COG2353	YceI-like domain
IDH70_08900	COG1652	LysM domain
IDH70_08965	COG1619	proteins homologs of microcin C7 resistance protein MccF
IDH70_08975	COG0668	transmembrane transport
IDH70_08980	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IDH70_08985	COG4575	ribosome binding
IDH70_08990	COG2261	transglycosylase associated protein
IDH70_08995	COG1733	regulation of RNA biosynthetic process
IDH70_09000	COG0702	epimerase
IDH70_09005	COG4774	siderophore transport
IDH70_09010	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IDH70_09040	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IDH70_09045	COG3381	protein complex oligomerization
IDH70_09050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IDH70_09060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IDH70_09060	COG0519	Catalyzes the synthesis of GMP from XMP
IDH70_09085	COG0840	transmembrane signaling receptor activity
IDH70_09090	COG0583	DNA-binding transcription factor activity
IDH70_09095	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_09105	COG3210	domain, Protein
IDH70_09145	COG3122	Protein conserved in bacteria
IDH70_09150	COG1278	Cold shock
IDH70_09170	COG0753	catalase activity
IDH70_09225	COG0012	GTP binding
IDH70_09235	COG0193	aminoacyl-tRNA hydrolase activity
IDH70_09260	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IDH70_09270	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IDH70_09275	COG2890	protein-(glutamine-N5) methyltransferase activity
IDH70_09285	COG2912	Transglutaminase-like superfamily
IDH70_09295	COG0387	Pfam Sodium calcium exchanger
IDH70_09300	COG4572	Cation transport regulator
IDH70_09305	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IDH70_09310	COG0515	serine threonine protein kinase
IDH70_09350	COG0840	transmembrane signaling receptor activity
IDH70_09355	COG3707	response regulator
IDH70_09360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IDH70_09365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IDH70_09370	COG1116	anion transmembrane transporter activity
IDH70_09375	COG2146	nitrite reductase [NAD(P)H] activity
IDH70_09375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IDH70_09380	COG0243	molybdopterin cofactor binding
IDH70_09385	COG1648	precorrin-2 dehydrogenase activity
IDH70_09385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IDH70_09390	COG4932	domain protein
IDH70_09400	COG1294	oxidase, subunit
IDH70_09405	COG1271	oxidase subunit
IDH70_09420	COG1012	belongs to the aldehyde dehydrogenase family
IDH70_09425	COG3724	N-succinylarginine dihydrolase activity
IDH70_09430	COG2988	succinylglutamate desuccinylase activity
IDH70_09435	COG3678	ATP-independent chaperone mediated protein folding
IDH70_09440	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_09445	COG0322	excinuclease ABC activity
IDH70_09450	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IDH70_09455	COG2814	Major facilitator Superfamily
IDH70_09460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IDH70_09470	COG0753	catalase activity
IDH70_09475	COG1823	symporter activity
IDH70_09480	COG1988	membrane-bound metal-dependent
IDH70_09485	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_09495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IDH70_09505	COG3001	Fructosamine kinase
IDH70_09520	COG3137	Salt-induced outer membrane protein
IDH70_09525	COG1294	oxidase, subunit
IDH70_09530	COG1271	oxidase subunit
IDH70_09540	COG3383	formate dehydrogenase (NAD+) activity
IDH70_09555	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_09555	COG3321	synthase
IDH70_09555	COG0604	alcohol dehydrogenase
IDH70_09570	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IDH70_09605	COG0776	regulation of translation
IDH70_09615	COG4139	cobalamin transport
IDH70_09620	COG0386	Belongs to the glutathione peroxidase family
IDH70_09630	COG0791	NLP P60 protein
IDH70_09635	COG2200	EAL domain
IDH70_09640	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IDH70_09645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IDH70_09650	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IDH70_09655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IDH70_09655	COG0574	Belongs to the PEP-utilizing enzyme family
IDH70_09665	COG0628	permease
IDH70_09670	COG0247	lactate metabolic process
IDH70_09670	COG0277	FAD linked oxidase domain protein
IDH70_09675	COG2050	protein possibly involved in aromatic compounds catabolism
IDH70_09685	COG0316	Belongs to the HesB IscA family
IDH70_09690	COG0719	Fe-S assembly protein
IDH70_09695	COG0396	ATPase activity
IDH70_09700	COG0719	Fe-S assembly protein
IDH70_09750	COG0307	riboflavin synthase, alpha
IDH70_09755	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IDH70_09760	COG2814	Major facilitator Superfamily
IDH70_09765	COG0583	DNA-binding transcription factor activity
IDH70_09770	COG1609	Transcriptional regulator
IDH70_09780	COG0791	NLP P60 protein
IDH70_09785	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IDH70_09795	COG0346	lactoylglutathione lyase activity
IDH70_09800	COG1309	transcriptional regulator
IDH70_09805	COG2194	sulfuric ester hydrolase activity
IDH70_09810	COG3313	Fe-S protein
IDH70_09815	COG4989	oxidoreductase activity
IDH70_09830	COG3133	Outer membrane lipoprotein
IDH70_09835	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IDH70_09840	COG3895	Periplasmic Protein
IDH70_09845	COG0259	pyridoxamine-phosphate oxidase activity
IDH70_09860	COG0625	glutathione transferase activity
IDH70_09865	COG3104	oligopeptide transport
IDH70_09870	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IDH70_09875	COG4660	Part of a membrane complex involved in electron transport
IDH70_09880	COG4659	FMN binding
IDH70_09885	COG4658	electron transport chain
IDH70_09890	COG4656	Part of a membrane complex involved in electron transport
IDH70_09895	COG2878	Part of a membrane complex involved in electron transport
IDH70_09900	COG4657	Part of a membrane complex involved in electron transport
IDH70_09915	COG1879	ABC-type sugar transport system periplasmic component
IDH70_09920	COG1129	ABC transporter
IDH70_09925	COG1172	Belongs to the binding-protein-dependent transport system permease family
IDH70_09930	COG1172	Belongs to the binding-protein-dependent transport system permease family
IDH70_09935	COG2160	L-arabinose isomerase activity
IDH70_09940	COG1069	ribulokinase activity
IDH70_09945	COG1879	ABC-type sugar transport system periplasmic component
IDH70_09955	COG1172	Belongs to the binding-protein-dependent transport system permease family
IDH70_09965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IDH70_09975	COG5339	Protein conserved in bacteria
IDH70_09980	COG1482	cell wall glycoprotein biosynthetic process
IDH70_09985	COG0114	fumarate hydratase activity
IDH70_09995	COG2814	Major facilitator Superfamily
IDH70_10000	COG0583	DNA-binding transcription factor activity
IDH70_10005	COG1940	carbohydrate kinase activity
IDH70_10010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IDH70_10035	COG0477	Major facilitator Superfamily
IDH70_10055	COG4221	oxidoreductase activity
IDH70_10060	COG0402	S-adenosylhomocysteine deaminase activity
IDH70_10070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IDH70_10080	COG0339	signal peptide processing
IDH70_10115	COG1464	Belongs to the NlpA lipoprotein family
IDH70_10155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IDH70_10160	COG0814	amino acid
IDH70_10165	COG4221	oxidoreductase activity
IDH70_10170	COG4221	oxidoreductase activity
IDH70_10175	COG2207	Transcriptional regulator
IDH70_10180	COG0778	Nitroreductase
IDH70_10190	COG2181	nitrate reductase activity
IDH70_10195	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IDH70_10200	COG1140	nitrate reductase beta subunit
IDH70_10205	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IDH70_10210	COG2223	nitrite transmembrane transporter activity
IDH70_10215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IDH70_10230	COG2271	Major facilitator Superfamily
IDH70_10250	COG3634	alkyl hydroperoxide reductase activity
IDH70_10265	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IDH70_10275	COG2382	esterase
IDH70_10305	COG2084	Dehydrogenase
IDH70_10310	COG4772	TonB-dependent receptor
IDH70_10315	COG1396	sequence-specific DNA binding
IDH70_10325	COG3729	General stress protein
IDH70_10365	COG4977	sequence-specific DNA binding
IDH70_10390	COG0477	Major facilitator Superfamily
IDH70_10400	COG2814	Major facilitator Superfamily
IDH70_10410	COG0235	Class ii aldolase
IDH70_10440	COG1012	belongs to the aldehyde dehydrogenase family
IDH70_10445	COG1609	Transcriptional regulator
IDH70_10450	COG2723	6-phospho-beta-galactosidase activity
IDH70_10455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IDH70_10455	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IDH70_10460	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IDH70_10465	COG0747	negative chemotaxis
IDH70_10470	COG2195	Cleaves the N-terminal amino acid of tripeptides
IDH70_10480	COG0436	Aminotransferase
IDH70_10485	COG0583	DNA-binding transcription factor activity
IDH70_10490	COG0840	transmembrane signaling receptor activity
IDH70_10500	COG5383	Protein conserved in bacteria
IDH70_10510	COG0583	DNA-binding transcription factor activity
IDH70_10515	COG2840	Smr protein MutS2
IDH70_10525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IDH70_10535	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IDH70_10540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IDH70_10550	COG0531	amino acid
IDH70_10560	COG0745	RESPONSE REGULATOR receiver
IDH70_10565	COG2205	protein histidine kinase activity
IDH70_10570	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IDH70_10580	COG3591	Belongs to the peptidase S1B family
IDH70_10585	COG1643	Atp-dependent helicase
IDH70_10590	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IDH70_10595	COG3784	Protein of unknown function (DUF1318)
IDH70_10605	COG2911	Protein conserved in bacteria
IDH70_10610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IDH70_10630	COG2203	Gaf domain
IDH70_10630	COG3706	GGDEF domain
IDH70_10630	COG4251	negative regulation of phosphorylation
IDH70_10630	COG5001	Diguanylate cyclase
IDH70_10670	COG2304	oxidoreductase activity
IDH70_10750	COG0037	tRNA processing
IDH70_10765	COG4166	transmembrane transport
IDH70_10770	COG2866	Carboxypeptidase
IDH70_10775	COG4948	Mandelate Racemase Muconate Lactonizing
IDH70_10780	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IDH70_10800	COG3768	UPF0283 membrane protein
IDH70_10805	COG3106	COG3106 Predicted ATPase
IDH70_10815	COG1983	PspC domain protein
IDH70_10825	COG1842	Phage shock protein A
IDH70_10830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IDH70_10835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IDH70_10860	COG4172	Belongs to the ABC transporter superfamily
IDH70_10870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IDH70_10875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IDH70_10875	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IDH70_10905	COG3182	Iron-regulated membrane protein
IDH70_10910	COG2200	EAL domain
IDH70_10915	COG0784	Response regulator, receiver
IDH70_10915	COG0835	chemotaxis
IDH70_10925	COG1263	PTS System
IDH70_10925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDH70_10935	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IDH70_10940	COG1966	Carbon starvation protein
IDH70_10950	COG5001	Diguanylate cyclase
IDH70_10955	COG1024	Enoyl-CoA hydratase
IDH70_10975	COG0023	Translation Initiation Factor
IDH70_10985	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IDH70_10990	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IDH70_10995	COG0671	phosphoesterase, PA-phosphatase related
IDH70_11005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IDH70_11035	COG0616	signal peptide processing
IDH70_11040	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_11055	COG0009	L-threonylcarbamoyladenylate synthase
IDH70_11070	COG0512	Glutamine amidotransferase of anthranilate synthase
IDH70_11075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IDH70_11080	COG0135	phosphoribosylanthranilate isomerase activity
IDH70_11080	COG0134	indole-3-glycerol-phosphate synthase activity
IDH70_11090	COG0159	tryptophan synthase activity
IDH70_11100	COG3047	cAMP biosynthetic process
IDH70_11105	COG0727	PFAM Uncharacterised protein family (UPF0153)
IDH70_11115	COG2917	probably involved in intracellular septation
IDH70_11130	COG2350	Protein conserved in bacteria
IDH70_11145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IDH70_11150	COG3099	Belongs to the UPF0263 family
IDH70_11160	COG0444	Belongs to the ABC transporter superfamily
IDH70_11165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IDH70_11185	COG2095	MarC family integral membrane protein
IDH70_11190	COG1012	belongs to the aldehyde dehydrogenase family
IDH70_11190	COG1454	alcohol dehydrogenase
IDH70_11215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IDH70_11220	COG0745	RESPONSE REGULATOR receiver
IDH70_11225	COG1752	Esterase of the alpha-beta hydrolase superfamily
IDH70_11230	COG3012	SEC-C Motif Domain Protein
IDH70_11235	COG0788	formyltetrahydrofolate deformylase activity
IDH70_11255	COG0708	Exodeoxyribonuclease III
IDH70_11265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IDH70_11270	COG0709	Synthesizes selenophosphate from selenide and ATP
IDH70_11275	COG0778	Nitroreductase
IDH70_11280	COG0616	signal peptide processing
IDH70_11285	COG0252	asparaginase activity
IDH70_11290	COG1335	isochorismatase
IDH70_11295	COG3139	Protein of unknown function (DUF1315)
IDH70_11300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IDH70_11315	COG0656	L-ascorbic acid biosynthetic process
IDH70_11320	COG3713	MltA-interacting MipA family protein
IDH70_11325	COG2766	serine protein kinase
IDH70_11330	COG2718	Belongs to the UPF0229 family
IDH70_11355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IDH70_11360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IDH70_11365	COG2719	SpoVR family
IDH70_11370	COG2186	Transcriptional regulator
IDH70_11390	COG0179	Fumarylacetoacetate (FAA) hydrolase
IDH70_11395	COG2951	lytic endotransglycosylase activity
IDH70_11405	COG0850	regulation of cytokinetic process
IDH70_11410	COG2894	cell division
IDH70_11415	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IDH70_11425	COG0318	PFAM AMP-dependent synthetase and ligase
IDH70_11430	COG3065	identical protein binding
IDH70_11435	COG1214	PFAM Peptidase M22, glycoprotease
IDH70_11440	COG1199	ATP-dependent helicase activity
IDH70_11445	COG0251	oxidation-reduction process
IDH70_11450	COG3140	Belongs to the UPF0181 family
IDH70_11465	COG1760	l-serine dehydratase
IDH70_11470	COG2200	EAL domain
IDH70_11475	COG1253	flavin adenine dinucleotide binding
IDH70_11480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDH70_11480	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IDH70_11485	COG3715	PTS system
IDH70_11490	COG3716	PTS system mannose fructose sorbose family IID component
IDH70_11500	COG1971	Probably functions as a manganese efflux pump
IDH70_11505	COG2226	methyltransferase
IDH70_11540	COG2814	Major facilitator Superfamily
IDH70_11545	COG0501	Belongs to the peptidase M48B family
IDH70_11555	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IDH70_11560	COG1956	GAF domain-containing protein
IDH70_11565	COG2995	paraquat-inducible protein a
IDH70_11570	COG3008	intermembrane lipid transfer
IDH70_11605	COG0454	-acetyltransferase
IDH70_11615	COG1396	sequence-specific DNA binding
IDH70_11640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IDH70_11680	COG2372	response to copper ion
IDH70_11690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IDH70_11695	COG1770	oligopeptidase
IDH70_11700	COG2979	Protein of unknown function (DUF533)
IDH70_11705	COG3141	response to X-ray
IDH70_11715	COG0800	Aldolase
IDH70_11720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IDH70_11725	COG1737	Transcriptional regulator
IDH70_11750	COG0582	viral genome integration into host DNA
IDH70_11755	COG0469	pyruvate kinase activity
IDH70_11760	COG0076	glutamate decarboxylase activity
IDH70_11765	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IDH70_11780	COG1560	Kdo2-lipid A biosynthetic process
IDH70_11785	COG0739	heme binding
IDH70_11790	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IDH70_11800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IDH70_11805	COG2255	four-way junction helicase activity
IDH70_11810	COG0632	four-way junction helicase activity
IDH70_11825	COG0494	nUDIX hydrolase
IDH70_11835	COG1335	isochorismatase
IDH70_11840	COG1801	Protein of unknown function DUF72
IDH70_11850	COG0500	methyltransferase
IDH70_11855	COG1280	lysine exporter protein (LysE YggA)
IDH70_11905	COG3142	Participates in the control of copper homeostasis
IDH70_11910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IDH70_11915	COG3102	Protein conserved in bacteria
IDH70_11920	COG0018	arginyl-trna synthetase
IDH70_11945	COG0745	RESPONSE REGULATOR receiver
IDH70_11955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IDH70_11965	COG0840	transmembrane signaling receptor activity
IDH70_11980	COG0835	chemotaxis
IDH70_12015	COG1877	trehalose-phosphatase activity
IDH70_12020	COG2135	peptidase activity
IDH70_12030	COG0583	DNA-binding transcription factor activity
IDH70_12035	COG2814	Major facilitator Superfamily
IDH70_12045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IDH70_12060	COG1702	phosphate starvation-inducible protein PhoH
IDH70_12070	COG2822	iron ion transport
IDH70_12080	COG5457	Domain of unknown function (DUF1127)
IDH70_12085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IDH70_12095	COG1522	sequence-specific DNA binding
IDH70_12120	COG1280	lysine exporter protein (LysE YggA)
IDH70_12140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IDH70_12150	COG3157	Type VI secretion system effector, Hcp
IDH70_12165	COG1126	abc transporter atp-binding protein
IDH70_12170	COG0765	amino acid transport
IDH70_12175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDH70_12220	COG0438	transferase activity, transferring glycosyl groups
IDH70_12220	COG1216	Glycosyl transferase, family 2
IDH70_12275	COG1278	Cold shock
IDH70_12290	COG1113	amino acid transport
IDH70_12325	COG1393	Belongs to the ArsC family
IDH70_12330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IDH70_12340	COG0659	secondary active sulfate transmembrane transporter activity
IDH70_12365	COG2249	NAD(P)H dehydrogenase (quinone) activity
IDH70_12375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IDH70_12380	COG1309	transcriptional regulator
IDH70_12405	COG0840	transmembrane signaling receptor activity
IDH70_12410	COG0251	oxidation-reduction process
IDH70_12420	COG2223	nitrite transmembrane transporter activity
IDH70_12425	COG0667	Aldo Keto reductase
IDH70_12435	COG0583	DNA-binding transcription factor activity
IDH70_12445	COG1677	Flagellar hook-basal body complex protein FliE
IDH70_12455	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IDH70_12470	COG2882	bacterial-type flagellum organization
IDH70_12480	COG1580	Controls the rotational direction of flagella during chemotaxis
IDH70_12490	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IDH70_12495	COG3190	flagellar
IDH70_12500	COG1338	Plays a role in the flagellum-specific transport system
IDH70_12520	COG0840	transmembrane signaling receptor activity
IDH70_12545	COG1215	transferase activity, transferring glycosyl groups
IDH70_12560	COG5475	Uncharacterized small protein (DUF2158)
IDH70_12570	COG2354	Protein conserved in bacteria
IDH70_12580	COG0697	spore germination
IDH70_12585	COG3727	T/G mismatch-specific endonuclease activity
IDH70_12590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IDH70_12610	COG1418	mRNA catabolic process
IDH70_12640	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_12650	COG0534	Mate efflux family protein
IDH70_12665	COG0641	radical SAM
IDH70_12670	COG3119	arylsulfatase activity
IDH70_12680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IDH70_12685	COG1120	ATPase activity
IDH70_12705	COG2080	2 iron, 2 sulfur cluster binding
IDH70_12710	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IDH70_12715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IDH70_12720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IDH70_12725	COG2076	Multidrug Resistance protein
IDH70_12730	COG2076	Multidrug Resistance protein
IDH70_12735	COG2252	PERMEase
IDH70_12750	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IDH70_12755	COG2188	Transcriptional regulator
IDH70_12760	COG5001	Diguanylate cyclase
IDH70_12760	COG3300	MHYT domain
IDH70_12765	COG0300	oxidoreductase activity
IDH70_12770	COG0028	Belongs to the TPP enzyme family
IDH70_12790	COG2851	Citrate transporter
IDH70_12795	COG1172	Belongs to the binding-protein-dependent transport system permease family
IDH70_12800	COG1129	ABC transporter
IDH70_12855	COG1289	transmembrane transporter activity
IDH70_12875	COG0243	molybdopterin cofactor binding
IDH70_12905	COG2925	Exonuclease
IDH70_12915	COG0531	amino acid
IDH70_12920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IDH70_12925	COG0174	glutamine synthetase
IDH70_12930	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IDH70_12935	COG1917	Cupin 2, conserved barrel domain protein
IDH70_12935	COG1396	sequence-specific DNA binding
IDH70_12940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IDH70_12945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IDH70_12955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IDH70_12965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IDH70_12980	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IDH70_12990	COG0140	phosphoribosyl-ATP diphosphatase activity
IDH70_12990	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IDH70_13000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IDH70_13050	COG2089	acid synthase
IDH70_13060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IDH70_13065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IDH70_13085	COG2244	polysaccharide biosynthetic process
IDH70_13090	COG2327	Polysaccharide pyruvyl transferase
IDH70_13095	COG1442	glycosyl transferase family 8
IDH70_13095	COG1216	Glycosyl transferase, family 2
IDH70_13125	COG0489	protein tyrosine kinase activity
IDH70_13125	COG3206	protein involved in exopolysaccharide biosynthesis
IDH70_13130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IDH70_13135	COG1596	polysaccharide export
IDH70_13140	COG1253	flavin adenine dinucleotide binding
IDH70_13145	COG2982	Protein involved in outer membrane biogenesis
IDH70_13150	COG0717	Belongs to the dCTP deaminase family
IDH70_13155	COG0572	uridine kinase
IDH70_13165	COG3447	MASE1 domain protein
IDH70_13165	COG5002	protein histidine kinase activity
IDH70_13165	COG5001	Diguanylate cyclase
IDH70_13170	COG0443	Heat shock 70 kDa protein
IDH70_13180	COG0667	Aldo Keto reductase
IDH70_13185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IDH70_13205	COG2205	protein histidine kinase activity
IDH70_13210	COG0745	RESPONSE REGULATOR receiver
IDH70_13215	COG0826	peptidase U32
IDH70_13220	COG1597	lipid kinase activity
IDH70_13225	COG4948	Mandelate Racemase Muconate Lactonizing
IDH70_13230	COG1063	alcohol dehydrogenase
IDH70_13235	COG2271	Major facilitator Superfamily
IDH70_13240	COG0246	Mannitol dehydrogenase
IDH70_13245	COG1802	Transcriptional regulator
IDH70_13250	COG1830	Aldolase
IDH70_13270	COG3209	COG3209 Rhs family protein
IDH70_13270	COG4104	PAAR repeat-containing protein
IDH70_13290	COG1129	ABC transporter
IDH70_13295	COG1172	Belongs to the binding-protein-dependent transport system permease family
IDH70_13305	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_13310	COG2951	lytic endotransglycosylase activity
IDH70_13320	COG4574	serine-type endopeptidase inhibitor activity
IDH70_13325	COG2814	Major facilitator Superfamily
IDH70_13330	COG3005	denitrification pathway
IDH70_13335	COG0243	molybdopterin cofactor binding
IDH70_13345	COG1454	alcohol dehydrogenase
IDH70_13355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IDH70_13355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IDH70_13365	COG1346	cytolysis
IDH70_13370	COG0295	cytidine deaminase activity
IDH70_13375	COG0281	malic enzyme
IDH70_13380	COG2949	membrane
IDH70_13390	COG1129	ABC transporter
IDH70_13400	COG1609	Transcriptional regulator
IDH70_13405	COG2311	Membrane
IDH70_13415	COG0477	Major facilitator Superfamily
IDH70_13420	COG0583	DNA-binding transcription factor activity
IDH70_13435	COG4771	TonB-dependent receptor
IDH70_13440	COG1120	ATPase activity
IDH70_13445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IDH70_13450	COG0833	amino acid
IDH70_13455	COG0583	DNA-binding transcription factor activity
IDH70_13465	COG2855	membrane
IDH70_13470	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IDH70_13485	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IDH70_13485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IDH70_13485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IDH70_13490	COG1105	Belongs to the carbohydrate kinase PfkB family
IDH70_13495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IDH70_13495	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IDH70_13505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IDH70_13515	COG0523	cobalamin synthesis protein
IDH70_13520	COG0671	phosphoesterase, PA-phosphatase related
IDH70_13525	COG0791	NLP P60 protein
IDH70_13530	COG2200	EAL domain
IDH70_13535	COG4166	transmembrane transport
IDH70_13540	COG4174	ABC transporter (Permease)
IDH70_13545	COG4239	(ABC) transporter, permease
IDH70_13550	COG4172	Belongs to the ABC transporter superfamily
IDH70_13560	COG2814	Major facilitator Superfamily
IDH70_13565	COG1187	pseudouridine synthase activity
IDH70_13570	COG1061	Type III restriction enzyme res subunit
IDH70_13575	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IDH70_13585	COG3082	Protein of unknown function (DUF1414)
IDH70_13590	COG3083	sulfuric ester hydrolase activity
IDH70_13610	COG0789	Transcriptional regulator
IDH70_13615	COG0697	spore germination
IDH70_13635	COG0840	transmembrane signaling receptor activity
IDH70_13645	COG4615	Cyclic peptide transporter
IDH70_13665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IDH70_13675	COG1132	(ABC) transporter
IDH70_13695	COG2223	nitrite transmembrane transporter activity
IDH70_13700	COG2198	Histidine kinase
IDH70_13700	COG0642	Histidine kinase
IDH70_13705	COG2197	response regulator
IDH70_13710	COG2205	protein histidine kinase activity
IDH70_13710	COG0784	Response regulator, receiver
IDH70_13715	COG2026	Addiction module toxin, RelE StbE family
IDH70_13725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IDH70_13755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IDH70_13760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IDH70_13765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IDH70_13795	COG1441	menaquinone biosynthetic process
IDH70_13800	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IDH70_13815	COG1169	isochorismate synthase
IDH70_13820	COG4575	ribosome binding
IDH70_13830	COG0431	NADPH-dependent FMN reductase
IDH70_13835	COG2153	protein acetylation
IDH70_13840	COG1007	ATP synthesis coupled electron transport
IDH70_13845	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IDH70_13850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IDH70_13855	COG0713	ATP synthesis coupled electron transport
IDH70_13860	COG0839	Belongs to the complex I subunit 6 family
IDH70_13890	COG0649	NAD binding
IDH70_13890	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IDH70_13900	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IDH70_13905	COG0583	DNA-binding transcription factor activity
IDH70_13910	COG0436	Aminotransferase
IDH70_13915	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IDH70_13920	COG0490	domain, Protein
IDH70_13920	COG0471	metal ion transport
IDH70_13925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IDH70_13930	COG3013	Belongs to the UPF0304 family
IDH70_13935	COG3092	negative regulation of chromosome organization
IDH70_13940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IDH70_13945	COG0280	phosphate acetyltransferase
IDH70_13945	COG0857	belongs to the CobB CobQ family
IDH70_13955	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IDH70_13960	COG3959	Transketolase, thiamine diphosphate binding domain
IDH70_13975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IDH70_13980	COG1609	Transcriptional regulator
IDH70_13990	COG0625	glutathione transferase activity
IDH70_13995	COG1090	epimerase
IDH70_14000	COG4598	ABC transporter
IDH70_14005	COG4160	amino acid transport
IDH70_14010	COG4215	(ABC) transporter
IDH70_14015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDH70_14020	COG0163	prenyltransferase activity
IDH70_14025	COG0583	DNA-binding transcription factor activity
IDH70_14030	COG0667	Aldo Keto reductase
IDH70_14040	COG3157	Type VI secretion system effector, Hcp
IDH70_14045	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IDH70_14050	COG1286	toxin biosynthetic process
IDH70_14055	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IDH70_14060	COG0285	dihydrofolate synthase activity
IDH70_14070	COG0586	Pfam SNARE associated Golgi protein
IDH70_14080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IDH70_14120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IDH70_14135	COG3101	peptidyl-lysine hydroxylation
IDH70_14140	COG0730	response to heat
IDH70_14150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IDH70_14160	COG2840	Smr protein MutS2
IDH70_14165	COG2062	phosphohistidine phosphatase, SixA
IDH70_14170	COG1250	3-hydroxyacyl-CoA dehydrogenase
IDH70_14170	COG1024	Enoyl-CoA hydratase
IDH70_14180	COG3691	Protein conserved in bacteria
IDH70_14185	COG2067	long-chain fatty acid transport protein
IDH70_14195	COG3088	subunit of a heme lyase
IDH70_14195	COG4235	cytochrome complex assembly
IDH70_14200	COG4235	cytochrome complex assembly
IDH70_14200	COG3088	subunit of a heme lyase
IDH70_14210	COG1138	Cytochrome C-type biogenesis protein
IDH70_14215	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IDH70_14220	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IDH70_14225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IDH70_14230	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IDH70_14240	COG2116	formate transmembrane transporter activity
IDH70_14265	COG2223	nitrite transmembrane transporter activity
IDH70_14275	COG2723	6-phospho-beta-galactosidase activity
IDH70_14325	COG0436	Aminotransferase
IDH70_14330	COG3275	phosphorelay sensor kinase activity
IDH70_14335	COG3279	Response regulator of the LytR AlgR family
IDH70_14340	COG0837	glucose binding
IDH70_14345	COG3961	Belongs to the TPP enzyme family
IDH70_14350	COG0667	Aldo Keto reductase
IDH70_14360	COG1914	H( )-stimulated, divalent metal cation uptake system
IDH70_14365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IDH70_14380	COG2116	formate transmembrane transporter activity
IDH70_14385	COG3415	Transposase
IDH70_14390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IDH70_14430	COG0583	DNA-binding transcription factor activity
IDH70_14435	COG0385	Bile acid
IDH70_14440	COG3530	Putative quorum-sensing-regulated virulence factor
IDH70_14450	COG3115	cell septum assembly
IDH70_14470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IDH70_14480	COG2205	protein histidine kinase activity
IDH70_14485	COG0745	RESPONSE REGULATOR receiver
IDH70_14490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IDH70_14495	COG1136	(ABC) transporter
IDH70_14495	COG0577	efflux transmembrane transporter activity
IDH70_14505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IDH70_14510	COG4208	sulfate ABC transporter
IDH70_14515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IDH70_14525	COG2837	iron assimilation
IDH70_14540	COG0456	acetyltransferase
IDH70_14545	COG0860	N-Acetylmuramoyl-L-alanine amidase
IDH70_14550	COG0408	coproporphyrinogen oxidase activity
IDH70_14565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IDH70_14570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IDH70_14610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IDH70_14615	COG5342	invasion associated locus B
IDH70_14620	COG1349	DNA-binding transcription factor activity
IDH70_14630	COG1129	ABC transporter
IDH70_14635	COG1172	Belongs to the binding-protein-dependent transport system permease family
IDH70_14640	COG1172	Belongs to the binding-protein-dependent transport system permease family
IDH70_14645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IDH70_14655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IDH70_14665	COG2181	nitrate reductase activity
IDH70_14670	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IDH70_14675	COG1140	nitrate reductase beta subunit
IDH70_14680	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IDH70_14685	COG2223	nitrite transmembrane transporter activity
IDH70_14690	COG2197	response regulator
IDH70_14700	COG3850	Histidine kinase
IDH70_14705	COG2197	response regulator
IDH70_14710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IDH70_14720	COG1393	Belongs to the ArsC family
IDH70_14725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IDH70_14735	COG0400	carboxylic ester hydrolase activity
IDH70_14740	COG1444	tRNA N-acetyltransferase activity
IDH70_14745	COG2321	neutral zinc metallopeptidase
IDH70_14755	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IDH70_14760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IDH70_14765	COG2716	regulation of RNA biosynthetic process
IDH70_14770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IDH70_14775	COG0628	permease
IDH70_14795	COG4783	chaperone-mediated protein folding
IDH70_14800	COG1393	Belongs to the ArsC family
IDH70_14825	COG2233	PERMEase
IDH70_14835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IDH70_14840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IDH70_14845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IDH70_14855	COG0573	inorganic phosphate transmembrane transporter activity
IDH70_14860	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IDH70_14865	COG0248	Ppx GppA phosphatase
IDH70_14870	COG0500	methyltransferase
IDH70_14875	COG2200	EAL domain
IDH70_14885	COG2239	Acts as a magnesium transporter
IDH70_14905	COG0517	IMP dehydrogenase activity
IDH70_14905	COG0516	GMP reductase activity
IDH70_14910	COG1570	exodeoxyribonuclease VII activity
IDH70_14920	COG2271	Major facilitator Superfamily
IDH70_14940	COG4993	Dehydrogenase
IDH70_14945	COG1645	bacterial-type flagellum-dependent swarming motility
IDH70_14950	COG1160	GTP binding
IDH70_14955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IDH70_14960	COG2976	Protein conserved in bacteria
IDH70_14965	COG0124	histidyl-tRNA synthetase
IDH70_14975	COG1426	Protein conserved in bacteria
IDH70_14985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IDH70_14990	COG0105	UTP biosynthetic process
IDH70_14995	COG4953	penicillin-binding protein 1C
IDH70_15000	COG2373	Large extracellular alpha-helical protein
IDH70_15005	COG2897	thiosulfate sulfurtransferase activity
IDH70_15015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IDH70_15020	COG2975	iron-sulfur cluster assembly
IDH70_15025	COG0633	Ferredoxin
IDH70_15035	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IDH70_15045	COG0822	iron-sulfur transferase activity
IDH70_15055	COG1959	2 iron, 2 sulfur cluster binding
IDH70_15065	COG0483	inositol monophosphate 1-phosphatase activity
IDH70_15070	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IDH70_15075	COG3683	transport system, periplasmic component
IDH70_15080	COG3711	transcriptional antiterminator
IDH70_15085	COG2814	Major facilitator Superfamily
IDH70_15090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IDH70_15100	COG1794	racemase activity, acting on amino acids and derivatives
IDH70_15105	COG0347	Belongs to the P(II) protein family
IDH70_15110	COG2204	response regulator
IDH70_15115	COG3170	Tfp pilus assembly protein FimV
IDH70_15120	COG2205	protein histidine kinase activity
IDH70_15125	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IDH70_15125	COG0047	phosphoribosylformylglycinamidine synthase activity
IDH70_15130	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IDH70_15140	COG0560	Phosphoserine phosphatase
IDH70_15145	COG1737	Transcriptional regulator
IDH70_15150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IDH70_15155	COG0736	holo-[acyl-carrier-protein] synthase activity
IDH70_15160	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IDH70_15165	COG1381	Involved in DNA repair and RecF pathway recombination
IDH70_15175	COG0571	ribonuclease III activity
IDH70_15185	COG0481	GTPase activity
IDH70_15190	COG3086	response to oxidative stress
IDH70_15195	COG3026	antisigma factor binding
IDH70_15215	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IDH70_15225	COG0513	Belongs to the DEAD box helicase family
IDH70_15230	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
IDH70_15235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IDH70_15240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IDH70_15245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IDH70_15250	COG0497	DNA recombination
IDH70_15265	COG2867	negative regulation of translational initiation
IDH70_15280	COG0582	viral genome integration into host DNA
IDH70_15295	COG1204	response to ionizing radiation
IDH70_15330	COG3311	Transcriptional regulator
IDH70_15335	COG3596	GTP binding
IDH70_15360	COG4983	Phage plasmid primase, P4 family domain protein
IDH70_15375	COG2003	Belongs to the UPF0758 family
IDH70_15435	COG2076	Multidrug Resistance protein
IDH70_15450	COG1966	Carbon starvation protein
IDH70_15455	COG4566	intracellular signal transduction
IDH70_15470	COG0494	nUDIX hydrolase
IDH70_15475	COG1349	DNA-binding transcription factor activity
IDH70_15485	COG4773	Receptor
IDH70_15490	COG4807	Protein conserved in bacteria
IDH70_15500	COG3275	phosphorelay sensor kinase activity
IDH70_15505	COG1764	response to oxidative stress
IDH70_15515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IDH70_15525	COG2040	homocysteine
IDH70_15530	COG0833	amino acid
IDH70_15540	COG4575	ribosome binding
IDH70_15560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IDH70_15580	COG2814	Major facilitator Superfamily
IDH70_15585	COG1846	Transcriptional regulator
IDH70_15590	COG1566	PFAM secretion protein HlyD family protein
IDH70_15595	COG2814	Major facilitator Superfamily
IDH70_15600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IDH70_15605	COG3118	belongs to the thioredoxin family
IDH70_15610	COG3148	PFAM DTW domain containing protein
IDH70_15615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IDH70_15615	COG1042	CoA-binding domain protein
IDH70_15615	COG0045	succinate-CoA ligase (ADP-forming) activity
IDH70_15620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IDH70_15625	COG5544	Lipoprotein
IDH70_15630	COG0477	Major facilitator Superfamily
IDH70_15660	COG0542	response to heat
IDH70_15665	COG1496	oxidoreductase activity
IDH70_15670	COG0564	pseudouridine synthase activity
IDH70_15675	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IDH70_15680	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IDH70_15685	COG0077	Prephenate dehydratase
IDH70_15685	COG1605	Chorismate mutase
IDH70_15690	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_15695	COG1605	Chorismate mutase
IDH70_15695	COG0287	Prephenate dehydrogenase
IDH70_15700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IDH70_15725	COG0228	four-way junction DNA binding
IDH70_15730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IDH70_15735	COG4137	Cytochrome C assembly protein
IDH70_15740	COG4536	flavin adenine dinucleotide binding
IDH70_15750	COG2918	glutathione biosynthetic process
IDH70_15755	COG1238	metal cluster binding
IDH70_15760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IDH70_15785	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IDH70_15805	COG1546	Belongs to the CinA family
IDH70_15810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IDH70_15815	COG2824	Alkylphosphonate utilization operon protein PhnA
IDH70_15820	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IDH70_15845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IDH70_15850	COG4942	peptidase
IDH70_15850	COG1388	LysM domain
IDH70_15855	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IDH70_15865	COG0585	pseudouridine synthase activity
IDH70_15875	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IDH70_15880	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IDH70_15895	COG2895	sulfate adenylyltransferase (ATP) activity
IDH70_15905	COG1648	precorrin-2 dehydrogenase activity
IDH70_15905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IDH70_15910	COG2234	aminopeptidase activity
IDH70_15920	COG0175	sulfate reduction
IDH70_15925	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IDH70_15935	COG0720	synthase
IDH70_15940	COG0723	plastoquinol--plastocyanin reductase activity
IDH70_15940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IDH70_15945	COG0602	queuosine metabolic process
IDH70_15960	COG0504	CTP synthase activity
IDH70_15965	COG3956	TIGRFAM MazG family protein
IDH70_15970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IDH70_15975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IDH70_15985	COG1929	Belongs to the glycerate kinase type-1 family
IDH70_15990	COG2084	Dehydrogenase
IDH70_16000	COG4948	Mandelate Racemase Muconate Lactonizing
IDH70_16005	COG4948	Mandelate Racemase Muconate Lactonizing
IDH70_16010	COG2271	Major facilitator Superfamily
IDH70_16020	COG2721	sulfolactate sulfo-lyase activity
IDH70_16025	COG0716	FMN binding
IDH70_16030	COG0564	pseudouridine synthase activity
IDH70_16035	COG3098	single-species biofilm formation
IDH70_16045	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IDH70_16045	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IDH70_16050	COG1611	Belongs to the LOG family
IDH70_16070	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IDH70_16075	COG2363	Small membrane protein
IDH70_16080	COG0583	DNA-binding transcription factor activity
IDH70_16090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IDH70_16095	COG2166	iron-sulfur cluster assembly
IDH70_16100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IDH70_16105	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IDH70_16120	COG0860	N-Acetylmuramoyl-L-alanine amidase
IDH70_16125	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IDH70_16125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IDH70_16130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IDH70_16135	COG1074	ATP-dependent DNA helicase activity
IDH70_16140	COG1025	Belongs to the peptidase M16 family
IDH70_16145	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IDH70_16160	COG4795	General secretion pathway protein
IDH70_16175	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IDH70_16180	COG0747	negative chemotaxis
IDH70_16185	COG0601	transmembrane transport
IDH70_16190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IDH70_16195	COG0444	Belongs to the ABC transporter superfamily
IDH70_16200	COG4608	Belongs to the ABC transporter superfamily
IDH70_16205	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IDH70_16210	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IDH70_16220	COG1051	belongs to the nudix hydrolase family
IDH70_16225	COG3066	DNA modification
IDH70_16230	COG0861	Integral membrane protein TerC family
IDH70_16240	COG0667	Aldo Keto reductase
IDH70_16255	COG0204	Acyl-transferase
IDH70_16255	COG0318	PFAM AMP-dependent synthetase and ligase
IDH70_16265	COG0768	penicillin binding
IDH70_16275	COG1609	Transcriptional regulator
IDH70_16280	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_16290	COG2186	Transcriptional regulator
IDH70_16295	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IDH70_16300	COG2723	6-phospho-beta-galactosidase activity
IDH70_16305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IDH70_16310	COG1447	Phosphotransferase system cellobiose-specific component IIA
IDH70_16320	COG0583	DNA-binding transcription factor activity
IDH70_16330	COG2814	Major facilitator Superfamily
IDH70_16340	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IDH70_16350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IDH70_16355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IDH70_16360	COG4974	Belongs to the 'phage' integrase family
IDH70_16380	COG0354	folic acid binding
IDH70_16385	COG1272	protein, Hemolysin III
IDH70_16395	COG2723	6-phospho-beta-galactosidase activity
IDH70_16410	COG0509	glycine decarboxylation via glycine cleavage system
IDH70_16420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IDH70_16425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IDH70_16430	COG0006	proline dipeptidase activity
IDH70_16435	COG3079	Belongs to the UPF0149 family
IDH70_16440	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IDH70_16450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IDH70_16455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IDH70_16460	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IDH70_16465	COG0583	DNA-binding transcription factor activity
IDH70_16470	COG2968	Membrane
IDH70_16480	COG0668	transmembrane transport
IDH70_16485	COG0191	fructose-bisphosphate aldolase activity
IDH70_16490	COG0126	phosphoglycerate kinase activity
IDH70_16495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IDH70_16505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IDH70_16510	COG0501	Belongs to the peptidase M48B family
IDH70_16515	COG0028	Belongs to the TPP enzyme family
IDH70_16525	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
IDH70_16530	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_16560	COG1414	Transcriptional regulator
IDH70_16565	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_16580	COG2146	nitrite reductase [NAD(P)H] activity
IDH70_16590	COG1166	arginine decarboxylase activity
IDH70_16595	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IDH70_16600	COG2814	Major facilitator Superfamily
IDH70_16605	COG3091	SprT-like family
IDH70_16610	COG2356	endonuclease I
IDH70_16615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IDH70_16625	COG1678	Uncharacterized ACR, COG1678
IDH70_16630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IDH70_16635	COG2805	Type II/IV secretion system protein
IDH70_16640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IDH70_16645	COG0762	integral membrane protein
IDH70_16650	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IDH70_16655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IDH70_16675	COG3171	Protein conserved in bacteria
IDH70_16685	COG1194	a g-specific adenine glycosylase
IDH70_16695	COG0741	lytic transglycosylase activity
IDH70_16700	COG3210	domain, Protein
IDH70_16705	COG2831	hemolysin activation secretion protein
IDH70_16710	COG5564	TIM-barrel signal transduction protein
IDH70_16715	COG5441	Belongs to the UPF0261 family
IDH70_16725	COG3916	Acyl-homoserine-lactone synthase
IDH70_16735	COG1982	Orn Lys Arg decarboxylase major
IDH70_16740	COG1902	pentaerythritol trinitrate reductase activity
IDH70_16755	COG2375	cellular response to nickel ion
IDH70_16760	COG1695	Transcriptional regulator
IDH70_16765	COG1902	pentaerythritol trinitrate reductase activity
IDH70_16770	COG2814	Major facilitator Superfamily
IDH70_16780	COG1473	amidohydrolase
IDH70_16785	COG0625	glutathione transferase activity
IDH70_16845	COG1528	Iron-storage protein
IDH70_16850	COG5001	Diguanylate cyclase
IDH70_16860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IDH70_16900	COG2197	response regulator
IDH70_16905	COG4297	protein containing double-stranded beta helix domain
IDH70_16915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IDH70_16925	COG1028	Short-chain dehydrogenase reductase Sdr
IDH70_16930	COG0848	biopolymer transport protein
IDH70_16940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IDH70_16955	COG0626	cystathionine gamma-synthase activity
IDH70_16965	COG2207	Transcriptional regulator
IDH70_16970	COG0656	L-ascorbic acid biosynthetic process
IDH70_16975	COG2132	Multicopper oxidase
IDH70_16985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IDH70_16990	COG2249	NAD(P)H dehydrogenase (quinone) activity
IDH70_16995	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IDH70_17000	COG0187	DNA topoisomerase II activity
IDH70_17005	COG3150	esterase
IDH70_17010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IDH70_17015	COG3151	Protein conserved in bacteria
IDH70_17020	COG0494	nUDIX hydrolase
IDH70_17040	COG0754	glutathionylspermidine amidase activity
IDH70_17045	COG3384	dioxygenase
IDH70_17060	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IDH70_17075	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IDH70_17080	COG3025	triphosphatase activity
IDH70_17085	COG4991	sh3 domain protein
IDH70_17095	COG1968	undecaprenyl-diphosphatase activity
IDH70_17100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IDH70_17105	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IDH70_17115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IDH70_17120	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IDH70_17125	COG0358	DNA primase activity
IDH70_17175	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IDH70_17195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IDH70_17200	COG1401	restriction endodeoxyribonuclease activity
IDH70_17230	COG2199	diguanylate cyclase activity
IDH70_17235	COG0659	secondary active sulfate transmembrane transporter activity
IDH70_17240	COG0288	reversible hydration of carbon dioxide
IDH70_17245	COG1496	oxidoreductase activity
IDH70_17250	COG2197	response regulator
IDH70_17260	COG1902	pentaerythritol trinitrate reductase activity
IDH70_17260	COG0446	pyridine nucleotide-disulphide oxidoreductase
IDH70_17265	COG2813	Specifically methylates the guanine in position
IDH70_17270	COG1451	nucleotide metabolic process
IDH70_17275	COG0038	chloride channel
IDH70_17280	COG0673	inositol 2-dehydrogenase activity
IDH70_17290	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IDH70_17295	COG2721	sulfolactate sulfo-lyase activity
IDH70_17310	COG2271	Major facilitator Superfamily
IDH70_17320	COG0586	Pfam SNARE associated Golgi protein
IDH70_17325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IDH70_17330	COG1422	Protein of unknown function (DUF1090)
IDH70_17335	COG4575	ribosome binding
IDH70_17340	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
IDH70_17350	COG2259	Doxx family
IDH70_17355	COG0435	Glutathione S-transferase
IDH70_17360	COG0583	DNA-binding transcription factor activity
IDH70_17365	COG1741	Belongs to the pirin family
IDH70_17370	COG2823	Periplasmic or secreted lipoprotein
IDH70_17375	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IDH70_17380	COG0792	nuclease activity
IDH70_17385	COG3107	peptidoglycan biosynthetic process
IDH70_17390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IDH70_17400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IDH70_17400	COG3711	transcriptional antiterminator
IDH70_17405	COG2706	6-phosphogluconolactonase activity
IDH70_17420	COG3964	amidohydrolase
IDH70_17450	COG0312	modulator of DNA gyrase
IDH70_17455	COG3028	Belongs to the UPF0307 family
IDH70_17460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IDH70_17465	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IDH70_17470	COG2707	UPF0756 membrane protein
IDH70_17480	COG2105	PFAM AIG2 family protein
IDH70_17485	COG2911	Protein conserved in bacteria
IDH70_17490	COG0729	surface antigen
IDH70_17495	COG1253	flavin adenine dinucleotide binding
IDH70_17505	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IDH70_17510	COG1218	3'(2'),5'-bisphosphate nucleotidase
IDH70_17520	COG0545	Peptidyl-prolyl cis-trans isomerase
IDH70_17525	COG3061	Opacity-associated protein A
IDH70_17535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IDH70_17540	COG2965	DNA replication, synthesis of RNA primer
IDH70_17550	COG1073	alpha beta
IDH70_17565	COG1960	acyl-CoA dehydrogenase activity
IDH70_17570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IDH70_17575	COG0557	exoribonuclease II activity
IDH70_17585	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IDH70_17590	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IDH70_17600	COG0330	HflC and HflK could
IDH70_17605	COG0330	HflC and HflK could
IDH70_17610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IDH70_17615	COG1923	regulation of RNA biosynthetic process
IDH70_17620	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IDH70_17625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IDH70_17635	COG0802	atpase or kinase
IDH70_17640	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IDH70_17640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IDH70_17670	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IDH70_17675	COG1162	GTPase activity
IDH70_17680	COG0688	phosphatidylethanolamine metabolic process
IDH70_17685	COG1511	domain protein
IDH70_17685	COG3264	Mechanosensitive ion channel
IDH70_17690	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IDH70_17695	COG0840	transmembrane signaling receptor activity
IDH70_17700	COG1053	succinate dehydrogenase
IDH70_17705	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IDH70_17730	COG5510	response to toxic substance
IDH70_17745	COG1509	lysine 2,3-aminomutase activity
IDH70_17750	COG2197	response regulator
IDH70_17755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDH70_17755	COG2205	protein histidine kinase activity
IDH70_17765	COG3188	usher protein
IDH70_17780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IDH70_17785	COG3030	protein affecting phage T7 exclusion by the F plasmid
IDH70_17790	COG1027	Aspartate ammonia-lyase
IDH70_17795	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IDH70_17805	COG4232	protein-disulfide reductase activity
IDH70_17810	COG1309	transcriptional regulator
IDH70_17825	COG1403	HNH endonuclease
IDH70_17830	COG1263	PTS System
IDH70_17830	COG2190	(PTS) system
IDH70_17830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDH70_17835	COG1609	Transcriptional regulator
IDH70_17850	COG2274	protein secretion by the type I secretion system
IDH70_17870	COG2885	chlorophyll binding
IDH70_17870	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IDH70_17890	COG2207	Transcriptional regulator
IDH70_17890	COG3708	Transcriptional regulator
IDH70_17895	COG4993	Dehydrogenase
IDH70_17900	COG2814	Major facilitator Superfamily
IDH70_17905	COG0583	DNA-binding transcription factor activity
IDH70_17910	COG3546	catalase activity
IDH70_17915	COG3685	Protein conserved in bacteria
IDH70_17920	COG3729	General stress protein
IDH70_17925	COG2207	Transcriptional regulator
IDH70_17960	COG0823	Involved in the tonB-independent uptake of proteins
IDH70_17985	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IDH70_18005	COG0840	transmembrane signaling receptor activity
IDH70_18010	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IDH70_18015	COG1301	dicarboxylic acid transport
IDH70_18025	COG3162	membrane
IDH70_18030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IDH70_18040	COG1380	Effector of murein hydrolase LrgA
IDH70_18045	COG0583	DNA-binding transcription factor activity
IDH70_18050	COG0025	NhaP-type Na H and K H
IDH70_18055	COG2252	PERMEase
IDH70_18065	COG0789	Transcriptional regulator
IDH70_18075	COG2199	diguanylate cyclase activity
IDH70_18100	COG0840	transmembrane signaling receptor activity
IDH70_18145	COG0076	glutamate decarboxylase activity
IDH70_18150	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IDH70_18155	COG0306	phosphate transporter
IDH70_18170	COG0629	single-stranded DNA binding
IDH70_18175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IDH70_18180	COG1064	alcohol dehydrogenase
IDH70_18185	COG2315	Protein conserved in bacteria
IDH70_18190	COG0432	Pfam Uncharacterised protein family UPF0047
IDH70_18195	COG1448	Aminotransferase
IDH70_18205	COG1522	sequence-specific DNA binding
IDH70_18220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IDH70_18240	COG0735	belongs to the Fur family
IDH70_18250	COG0534	Mate efflux family protein
IDH70_18260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IDH70_18275	COG3161	chorismate lyase activity
IDH70_18285	COG4580	involved in the transport of maltose and maltodextrins
IDH70_18295	COG2182	Extracellular solute-binding protein
IDH70_18300	COG1175	transmembrane transport
IDH70_18310	COG3223	Belongs to the PsiE family
IDH70_18325	COG0527	aspartate kinase activity
IDH70_18340	COG1283	sodium-dependent phosphate transmembrane transporter activity
IDH70_18345	COG1410	methionine synthase
IDH70_18345	COG0646	methionine synthase
IDH70_18350	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IDH70_18380	COG0151	Belongs to the GarS family
IDH70_18395	COG3068	Protein conserved in bacteria
IDH70_18405	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IDH70_18415	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
IDH70_18420	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IDH70_18430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IDH70_18440	COG2022	thiamine diphosphate biosynthetic process
IDH70_18455	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IDH70_18470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IDH70_18485	COG0250	Participates in transcription elongation, termination and antitermination
IDH70_18530	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IDH70_18560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IDH70_18565	COG1739	Uncharacterized protein family UPF0029
IDH70_18570	COG0006	proline dipeptidase activity
IDH70_18575	COG1024	Enoyl-CoA hydratase
IDH70_18575	COG1250	3-hydroxyacyl-CoA dehydrogenase
IDH70_18600	COG0084	hydrolase, TatD family'
IDH70_18605	COG0805	protein transport
IDH70_18620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IDH70_18630	COG2226	methyltransferase
IDH70_18635	COG1322	Protein conserved in bacteria
IDH70_18645	COG0412	Dienelactone hydrolase
IDH70_18650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IDH70_18655	COG0583	DNA-binding transcription factor activity
IDH70_18665	COG0697	spore germination
IDH70_18670	COG2271	Major facilitator Superfamily
IDH70_18675	COG0584	glycerophosphoryl diester phosphodiesterase
IDH70_18680	COG0561	phosphatase activity
IDH70_18685	COG2267	carboxylic ester hydrolase activity
IDH70_18690	COG1280	lysine exporter protein (LysE YggA)
IDH70_18695	COG1280	lysine exporter protein (LysE YggA)
IDH70_18705	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
IDH70_18710	COG2050	protein possibly involved in aromatic compounds catabolism
IDH70_18715	COG2962	Rard protein
IDH70_18720	COG3180	Ammonia monooxygenase
IDH70_18730	COG0210	DNA helicase
IDH70_18735	COG1011	Hydrolase
IDH70_18745	COG3159	Protein conserved in bacteria
IDH70_18750	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IDH70_18790	COG0181	hydroxymethylbilane synthase activity
IDH70_18800	COG2959	enzyme of heme biosynthesis
IDH70_18805	COG3071	HemY protein
IDH70_18830	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IDH70_18840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IDH70_18845	COG2244	polysaccharide biosynthetic process
IDH70_18850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IDH70_18855	COG0456	acetyltransferase
IDH70_18860	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IDH70_18865	COG1088	dTDP-glucose 4,6-dehydratase activity
IDH70_18870	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IDH70_18875	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IDH70_18880	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IDH70_18885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IDH70_18890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IDH70_18895	COG3118	belongs to the thioredoxin family
IDH70_18905	COG0248	Ppx GppA phosphatase
IDH70_18920	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IDH70_18925	COG0583	DNA-binding transcription factor activity
IDH70_18935	COG0129	dihydroxy-acid dehydratase activity
IDH70_18940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IDH70_18945	COG3978	acetolactate synthase activity
IDH70_18965	COG3085	chromosome segregation
IDH70_18970	COG0583	DNA-binding transcription factor activity
IDH70_19030	COG1309	transcriptional regulator
IDH70_19035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IDH70_19045	COG0678	peroxiredoxin activity
IDH70_19045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IDH70_19055	COG0137	argininosuccinate synthase activity
IDH70_19065	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IDH70_19070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IDH70_19075	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IDH70_19090	COG0527	aspartate kinase activity
IDH70_19090	COG0460	homoserine dehydrogenase
IDH70_19095	COG0626	cystathionine gamma-synthase activity
IDH70_19100	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
IDH70_19110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IDH70_19115	COG1609	Transcriptional regulator
IDH70_19120	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IDH70_19125	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IDH70_19135	COG1575	Belongs to the MenA family. Type 1 subfamily
IDH70_19140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IDH70_19145	COG3074	FtsZ-dependent cytokinesis
IDH70_19150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IDH70_19160	COG1494	fructose-1,6-bisphosphatase
IDH70_19165	COG2814	Major facilitator Superfamily
IDH70_19175	COG3152	Membrane
IDH70_19185	COG0149	triose-phosphate isomerase activity
IDH70_19195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IDH70_19200	COG0205	6-phosphofructokinase activity
IDH70_19210	COG3678	ATP-independent chaperone mediated protein folding
IDH70_19215	COG0745	RESPONSE REGULATOR receiver
IDH70_19220	COG2205	protein histidine kinase activity
IDH70_19225	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IDH70_19240	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IDH70_19245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IDH70_19250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IDH70_19255	COG4942	peptidase
IDH70_19260	COG2861	carbohydrate metabolic process
IDH70_19265	COG0438	transferase activity, transferring glycosyl groups
IDH70_19285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IDH70_19295	COG0859	PFAM glycosyl transferase family 9
IDH70_19315	COG0438	transferase activity, transferring glycosyl groups
IDH70_19325	COG1216	Glycosyl transferase, family 2
IDH70_19330	COG0859	PFAM glycosyl transferase family 9
IDH70_19340	COG1519	Transferase
IDH70_19355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IDH70_19360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IDH70_19370	COG2003	Belongs to the UPF0758 family
IDH70_19375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IDH70_19395	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IDH70_19405	COG1131	(ABC) transporter
IDH70_19420	COG1561	YicC-like family, N-terminal region
IDH70_19435	COG2244	polysaccharide biosynthetic process
IDH70_19440	COG2860	membrane
IDH70_19450	COG0194	GDP metabolic process
IDH70_19455	COG1758	RNA polymerase activity
IDH70_19460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IDH70_19465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IDH70_19470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IDH70_19475	COG2233	PERMEase
IDH70_19480	COG2982	Protein involved in outer membrane biogenesis
IDH70_19485	COG0456	acetyltransferase
IDH70_19490	COG1490	D-aminoacyl-tRNA deacylase activity
IDH70_19500	COG1011	Hydrolase
IDH70_19515	COG3852	Histidine kinase
IDH70_19520	COG2204	response regulator
IDH70_19530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IDH70_19535	COG3078	GTPase activator activity
IDH70_19545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IDH70_19545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IDH70_19550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IDH70_19555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IDH70_19560	COG3084	Protein conserved in bacteria
IDH70_19570	COG1763	Mo-molybdopterin cofactor biosynthetic process
IDH70_19595	COG0477	Major facilitator Superfamily
IDH70_19600	COG1609	Transcriptional regulator
IDH70_19605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IDH70_19610	COG1879	ABC-type sugar transport system periplasmic component
IDH70_19615	COG1172	Belongs to the binding-protein-dependent transport system permease family
IDH70_19620	COG1129	ABC transporter
IDH70_19650	COG3111	PFAM Bacterial OB fold (BOF) protein
IDH70_19655	COG0745	RESPONSE REGULATOR receiver
IDH70_19660	COG0642	Histidine kinase
IDH70_19675	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IDH70_19680	COG1522	sequence-specific DNA binding
IDH70_19685	COG0716	FMN binding
IDH70_19700	COG3312	ion transport
IDH70_19705	COG0356	it plays a direct role in the translocation of protons across the membrane
IDH70_19715	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IDH70_19735	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IDH70_19745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IDH70_19760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IDH70_19765	COG0573	inorganic phosphate transmembrane transporter activity
IDH70_19770	COG0581	inorganic phosphate transmembrane transporter activity
IDH70_19775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IDH70_19780	COG0704	Plays a role in the regulation of phosphate uptake
IDH70_19785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IDH70_19790	COG2252	PERMEase
IDH70_19800	COG2197	response regulator
IDH70_19805	COG1538	Outer membrane efflux protein
IDH70_19840	COG3121	Chaperone
IDH70_19865	COG0706	membrane insertase activity
IDH70_19880	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IDH70_19945	COG1192	Involved in chromosome partitioning
IDH70_20035	COG0210	DNA helicase
IDH70_20175	COG4245	von Willebrand factor, type A
IDH70_20180	COG4245	von Willebrand factor, type A
IDH70_20210	COG1358	cellular component organization or biogenesis
IDH70_20325	COG3550	peptidyl-serine autophosphorylation
IDH70_20390	COG1357	PFAM Pentapeptide repeats (8 copies)
IDH70_20470	COG0789	Transcriptional regulator
IDH70_20540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IDH70_20590	COG0840	transmembrane signaling receptor activity
IDH70_20605	COG1349	DNA-binding transcription factor activity
IDH70_20610	COG2084	Dehydrogenase
IDH70_20685	COG2771	luxR family
IDH70_20690	COG2771	luxR family
IDH70_20715	COG2194	sulfuric ester hydrolase activity
IDH70_20725	COG2205	protein histidine kinase activity
IDH70_20805	COG0659	secondary active sulfate transmembrane transporter activity
IDH70_20810	COG0589	response to stress
IDH70_20815	COG1393	Belongs to the ArsC family
IDH70_20820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IDH70_20825	COG0640	Transcriptional regulator
IDH70_20830	COG0431	NADPH-dependent FMN reductase
IDH70_20835	COG2801	Transposase and inactivated derivatives
IDH70_20855	COG2801	Transposase and inactivated derivatives
IDH70_20885	COG3039	Transposase
IDH70_20925	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IDH70_20925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IDH70_20945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IDH70_20960	COG3157	Type VI secretion system effector, Hcp
IDH70_21115	COG2026	Addiction module toxin, RelE StbE family
IDH70_21120	COG3077	Addiction module antitoxin, RelB DinJ family
IDH70_21125	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IDH70_21135	COG3547	Transposase (IS116 IS110 IS902 family)
IDH70_21140	COG2801	Transposase and inactivated derivatives
IDH70_21360	COG2890	protein-(glutamine-N5) methyltransferase activity
IDH70_21420	COG0338	D12 class N6 adenine-specific DNA methyltransferase