locus-tag	class	description
AAX08_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AAX08_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AAX08_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AAX08_00025	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AAX08_00035	ENOG4105M4H	endoribonuclease L-psp
AAX08_00050	ENOG4105BZ1	(ABC) transporter
AAX08_00055	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AAX08_00060	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AAX08_00065	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AAX08_00070	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AAX08_00080	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AAX08_00125	ENOG4105C5H	ABC transporter
AAX08_00130	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AAX08_00135	ENOG4105DNZ	Alpha Beta Hydrolase
AAX08_00145	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AAX08_00150	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AAX08_00165	ENOG4105I08	Pseudouridine synthase
AAX08_00170	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AAX08_00175	ENOG4107QSI	ABC, transporter
AAX08_00180	ENOG4105DEN	Luciferase family
AAX08_00190	ENOG4105C34	Pseudouridine synthase
AAX08_00195	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AAX08_00200	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
AAX08_00225	ENOG4105F04	LysR family Transcriptional regulator
AAX08_00230	ENOG4105CGF	Aromatic amino acid aminotransferase
AAX08_00235	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AAX08_00245	ENOG4108K5H	permease YjgP YjgQ family protein
AAX08_00250	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AAX08_00255	ENOG4105BZM	domain protein
AAX08_00265	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
AAX08_00270	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
AAX08_00275	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AAX08_00280	ENOG4105E33	succinate dehydrogenase
AAX08_00335	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AAX08_00340	ENOG4105C7S	Dehydrogenase
AAX08_00350	ENOG4105EUR	Domain-Containing protein
AAX08_00360	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AAX08_00365	ENOG4107QP8	phosphohexose isomerase
AAX08_00370	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AAX08_00385	ENOG4108M3P	Membrane
AAX08_00395	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AAX08_00400	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AAX08_00405	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AAX08_00410	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AAX08_00415	ENOG4105CHU	acetyl-coa acetyltransferase
AAX08_00435	ENOG4105DHS	permease protein
AAX08_00440	ENOG4105CM4	permease protein
AAX08_00450	ENOG4108IPW	abc transporter atp-binding protein
AAX08_00455	ENOG4108IA2	Sodium pantothenate symporter
AAX08_00460	ENOG4105RG0	Membrane
AAX08_00475	ENOG4105YK5	50S ribosomal protein L36
AAX08_00480	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AAX08_00495	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AAX08_00500	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AAX08_00505	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AAX08_00520	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AAX08_00530	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AAX08_00535	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AAX08_00540	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AAX08_00545	ENOG4105NRA	50s ribosomal protein l31 type b
AAX08_00555	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AAX08_00570	ENOG4105FKN	transcriptional regulator, AsnC family
AAX08_00575	ENOG4106KPZ	rard protein
AAX08_00580	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AAX08_00590	ENOG4108YI8	ABC transporter
AAX08_00595	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
AAX08_00600	ENOG4107Z6I	Thiamine biosynthesis protein
AAX08_00605	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AAX08_00610	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AAX08_00660	ENOG4107V1M	polysaccharide export protein
AAX08_00665	ENOG4107V1M	polysaccharide export protein
AAX08_00670	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AAX08_00675	ENOG4105C3F	Signal peptidase i
AAX08_00680	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AAX08_00685	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AAX08_00690	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AAX08_00695	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AAX08_00700	ENOG4108WHA	ompa motb domain protein
AAX08_00715	ENOG4105QYK	bacteriophage lambda Bor protein homolog
AAX08_00720	ENOG4105QYK	bacteriophage lambda Bor protein homolog
AAX08_00725	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AAX08_00730	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AAX08_00735	ENOG4105C1J	atp-dependent rna helicase
AAX08_00745	ENOG4105WD1	Membrane
AAX08_00760	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AAX08_00770	ENOG4108ZAI	phosphatidylglycerophosphatase a
AAX08_00780	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AAX08_00785	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AAX08_00790	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AAX08_00795	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AAX08_00805	ENOG4105CUV	Homoserine Kinase
AAX08_00810	ENOG4105E7A	Glutamine amidotransferase
AAX08_00815	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AAX08_00820	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AAX08_00850	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AAX08_00870	ENOG4105CQB	FAD linked oxidase domain protein
AAX08_00885	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AAX08_00890	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AAX08_00900	ENOG4105CJN	penicillin-binding protein
AAX08_00905	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AAX08_00910	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AAX08_00915	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AAX08_00920	ENOG4108UKI	Enoyl-CoA hydratase
AAX08_00925	ENOG4105E5M	Multidrug resistance protein D
AAX08_00930	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AAX08_00935	ENOG41085PJ	rdd domain containing protein
AAX08_00940	ENOG41082RQ	UPF0102 protein
AAX08_00955	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AAX08_00960	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AAX08_00965	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AAX08_00970	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AAX08_00975	ENOG4107GFK	fumarate
AAX08_00980	ENOG4107QQB	Ribonuclease E
AAX08_00985	ENOG4105EI2	Pseudouridine synthase
AAX08_00990	ENOG4105C9X	ppx gppa phosphatase
AAX08_01005	ENOG4105II7	pyrroline-5-carboxylate reductase
AAX08_01010	ENOG4108VIA	integral membrane protein
AAX08_01015	ENOG4105DWF	phosphomethylpyrimidine kinase
AAX08_01035	ENOG4105D4P	Coproporphyrinogen iii oxidase
AAX08_01045	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AAX08_01050	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AAX08_01055	ENOG4105CK7	Sodium proline symporter
AAX08_01060	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AAX08_01075	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AAX08_01090	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AAX08_01100	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AAX08_01110	ENOG4105DFP	Integrase
AAX08_01165	ENOG4107T5V	SNARE associated Golgi
AAX08_01185	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AAX08_01190	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AAX08_01195	ENOG4107S76	domain protein
AAX08_01200	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AAX08_01220	ENOG4107RET	Isocitrate lyase
AAX08_01235	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AAX08_01240	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AAX08_01245	ENOG4105CN1	protease
AAX08_01250	ENOG4105EB3	Histidine kinase
AAX08_01255	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AAX08_01265	ENOG4105DS1	cytochrome b561
AAX08_01275	ENOG4107QMS	site-determining protein
AAX08_01310	ENOG4105D3R	alkyl hydroperoxide reductase
AAX08_01315	ENOG4105Z2P	Protein of unknown function (DUF465)
AAX08_01320	ENOG4108JU3	Alkyl hydroperoxide reductase
AAX08_01330	ENOG4105C9B	Cysteine desulfurase
AAX08_01340	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AAX08_01350	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AAX08_01360	ENOG4105CVE	Lytic murein transglycosylase
AAX08_01370	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AAX08_01380	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AAX08_01385	ENOG410838B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AAX08_01390	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AAX08_01395	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
AAX08_01405	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AAX08_01410	ENOG4105E0C	molybdate abc transporter
AAX08_01415	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AAX08_01420	ENOG41077A9	carbonic anhydrase
AAX08_01430	ENOG4105WH1	Two component transcriptional regulator luxr family
AAX08_01435	ENOG4105BZU	Histidine kinase
AAX08_01445	ENOG4105DQQ	Major facilitator superfamily MFS_1
AAX08_01455	ENOG4106032	Glutathionylspermidine synthase
AAX08_01465	ENOG41060IM	Heme exporter protein
AAX08_01475	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AAX08_01480	ENOG4105D01	(LipO)protein
AAX08_01485	ENOG4108UMI	ABC transporter, permease
AAX08_01495	ENOG4105C5I	Dehydrogenase
AAX08_01500	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AAX08_01510	ENOG4105C0P	Mg chelatase subunit ChlI
AAX08_01515	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AAX08_01530	ENOG4105CTB	Polyprenyl synthetase
AAX08_01535	ENOG4105CEN	a g-specific adenine glycosylase
AAX08_01555	ENOG4108YZA	Nitrogen regulatory protein pii
AAX08_01560	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AAX08_01565	ENOG4105CNI	cell division protein FtsW
AAX08_01570	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AAX08_01575	ENOG4105SVQ	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (By similarity)
AAX08_01585	ENOG4105FAV	ABC, transporter
AAX08_01590	ENOG4105FDK	ABC transporter
AAX08_01595	ENOG4105MYN	Zinc uptake regulation protein
AAX08_01610	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AAX08_01615	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AAX08_01620	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AAX08_01625	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AAX08_01630	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AAX08_01635	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AAX08_01640	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AAX08_01645	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AAX08_01650	ENOG4107EXC	regulatoR
AAX08_01655	ENOG4105JJR	Histidine kinase
AAX08_01660	ENOG4105E0F	Histidine kinase
AAX08_01665	ENOG4105K5M	30s ribosomal protein S16
AAX08_01670	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AAX08_01675	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AAX08_01680	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AAX08_01690	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AAX08_01700	ENOG4105C3M	thioredoxin reductase
AAX08_01710	ENOG4105CJ2	(LipO)protein
AAX08_01725	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AAX08_01730	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AAX08_01735	ENOG4108UKZ	OsmC family
AAX08_01745	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AAX08_01755	ENOG4105HF0	Membrane
AAX08_01765	ENOG4108UUM	single-stranded DNA-binding protein
AAX08_01775	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AAX08_01780	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AAX08_01785	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AAX08_01790	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AAX08_01805	ENOG4105CKW	Inner membrane protein yedI
AAX08_01815	ENOG4105VCC	30S ribosomal protein S21
AAX08_01840	ENOG4107SJW	iron permease, FTR1
AAX08_01855	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AAX08_01860	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AAX08_01865	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AAX08_01870	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AAX08_01880	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AAX08_01885	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AAX08_01895	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AAX08_01915	ENOG4105C22	threonyL-tRNA synthetase
AAX08_01930	ENOG4105CC5	ABC transporter
AAX08_01935	ENOG4105CC5	ABC transporter
AAX08_01940	ENOG4105C5W	Aldolase
AAX08_01975	ENOG4105CE9	30S ribosomal protein S2
AAX08_01980	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AAX08_01990	ENOG4105D7Z	glutathione synthase
AAX08_02000	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AAX08_02015	ENOG4105DFU	Cell wall formation (By similarity)
AAX08_02025	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AAX08_02055	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AAX08_02085	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AAX08_02090	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AAX08_02095	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AAX08_02100	ENOG4105DB7	PHP domain protein
AAX08_02105	ENOG4105Y3E	Modulates RecA activity (By similarity)
AAX08_02110	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AAX08_02115	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AAX08_02130	ENOG4105C25	Primosomal protein n'
AAX08_02135	ENOG4105KME	endoribonuclease L-psp
AAX08_02145	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AAX08_02150	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AAX08_02155	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AAX08_02160	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AAX08_02180	ENOG4105C5A	transporter
AAX08_02190	ENOG4107R7A	Allophanate hydrolase subunit 2
AAX08_02195	ENOG4105P4J	Allophanate hydrolase, subunit 1
AAX08_02200	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AAX08_02205	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AAX08_02210	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AAX08_02275	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
AAX08_02305	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AAX08_02310	ENOG4107QIJ	Aconitate hydratase 2
AAX08_02315	ENOG4108JPW	Aminotransferase
AAX08_02320	ENOG4107QMH	DNA methylase
AAX08_02330	ENOG4105DY8	decarboxylase
AAX08_02345	ENOG4105DWV	Homoserine O-trans-acetylase
AAX08_02350	ENOG4105DWV	Homoserine O-trans-acetylase
AAX08_02355	ENOG4108JQ5	ABC transporter
AAX08_02360	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AAX08_02365	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AAX08_02375	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
AAX08_02380	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AAX08_02385	ENOG4105EN6	Membrane
AAX08_02395	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AAX08_02405	ENOG4105E9K	Isocitrate dehydrogenase
AAX08_02410	ENOG4105DZ2	Transcriptional regulator
AAX08_02420	ENOG4105CUB	amino acid
AAX08_02435	ENOG4105C6K	Malic enzyme
AAX08_02440	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
AAX08_02445	ENOG4105D52	delta-aminolevulinic acid dehydratase
AAX08_02455	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AAX08_02465	ENOG4105HDD	phospholipase
AAX08_02500	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AAX08_02505	ENOG4105CD8	aminopeptidase N
AAX08_02510	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AAX08_02515	ENOG4108TSD	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AAX08_02520	ENOG4106371	Methyltransferase
AAX08_02545	ENOG4108JJB	ABC transporter
AAX08_02565	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AAX08_02625	ENOG4105DTN	riboflavin biosynthesis protein ribF
AAX08_02635	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AAX08_02640	ENOG4105E4C	Lytic transglycosylase catalytic
AAX08_02645	ENOG4107RZC	phospholipase d
AAX08_02655	ENOG4105C8N	cysteinyl-tRNA synthetase
AAX08_02660	ENOG4105D6E	homoserine dehydrogenase
AAX08_02670	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AAX08_02685	ENOG4105DA5	(ABC) transporter
AAX08_02690	ENOG4105E3A	(ABC) transporter
AAX08_02695	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AAX08_02705	ENOG4108VPT	UPF0234 protein
AAX08_02710	ENOG41090Q8	at two internal lysine residues, thereby converting it to the active toxin. The acyl donor is ACP
AAX08_02720	ENOG4108JJA	ABC, transporter
AAX08_02755	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AAX08_02775	ENOG4105C58	cytochrome c oxidase accessory protein ccog
AAX08_02790	ENOG4105UYK	outer membrane protein a
AAX08_02800	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AAX08_02815	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AAX08_02830	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AAX08_02840	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AAX08_02850	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AAX08_02860	ENOG4105D0A	hydroxylase
AAX08_02875	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AAX08_02885	ENOG4105VW4	glutaredoxin 3
AAX08_02890	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AAX08_02895	ENOG41080C8	DUF218 domain
AAX08_02915	ENOG4105VEJ	Heat shock protein
AAX08_02925	ENOG4105C75	arginyL-tRNA synthetase
AAX08_02930	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AAX08_02935	ENOG4105C8U	phosphate abc transporter
AAX08_02940	ENOG4105E2Z	phosphate ABC transporter (Permease
AAX08_02945	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AAX08_02950	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AAX08_02955	ENOG4105BZU	Histidine kinase
AAX08_02965	ENOG4105C7B	Threonine dehydratase
AAX08_02970	ENOG4105CDY	transcriptional regulatory protein
AAX08_02980	ENOG4105EYW	Ion transport protein
AAX08_02990	ENOG4107U91	Rhomboid family
AAX08_02995	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AAX08_03010	ENOG4105CX6	glutaminyL-tRNA synthetase
AAX08_03015	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AAX08_03020	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AAX08_03040	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AAX08_03055	ENOG4105C8T	Leucyl-tRNA synthetase
AAX08_03060	ENOG4105KUZ	arsenate reductase
AAX08_03075	ENOG4105CAS	nag kinase
AAX08_03080	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AAX08_03090	ENOG4105VAW	lrga family
AAX08_03095	ENOG41067MG	lrgb family
AAX08_03100	ENOG4105D0M	Protease HtpX homolog
AAX08_03115	ENOG4105CC0	LysR family Transcriptional regulator
AAX08_03120	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AAX08_03125	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AAX08_03130	ENOG4105EHM	Aminoglycoside phosphotransferase
AAX08_03135	ENOG4108S0S	Nucleotidyl transferase
AAX08_03150	ENOG4105RPH	Inner membrane protein YddG
AAX08_03155	ENOG4105RPH	Inner membrane protein YddG
AAX08_03160	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AAX08_03170	ENOG4107MKT	Stringent starvation protein a
AAX08_03185	ENOG4105EIX	cytochrome c1
AAX08_03190	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AAX08_03195	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AAX08_03200	ENOG4108UJD	30S ribosomal protein S9
AAX08_03205	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AAX08_03210	ENOG4106H78	methyltransferase
AAX08_03220	ENOG4105DA4	cytochrome c-type biogenesis protein
AAX08_03225	ENOG4107QX9	Thiol disulfide interChange protein
AAX08_03230	ENOG4105KWW	Biogenesis protein
AAX08_03240	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AAX08_03250	ENOG4105K59	histidine triad (HIT) protein
AAX08_03260	ENOG4105DP0	ferredoxin-NADP reductase
AAX08_03265	ENOG4108R96	Methyltransferase, YaeB family
AAX08_03280	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AAX08_03290	ENOG4105CHU	acetyl-coa acetyltransferase
AAX08_03295	ENOG4105CHR	reductase
AAX08_03310	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AAX08_03315	ENOG4105C01	Dihydroxy-acid dehydratase
AAX08_03325	ENOG4105C02	permease
AAX08_03330	ENOG4105CSM	endonuclease III
AAX08_03340	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AAX08_03345	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AAX08_03350	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AAX08_03355	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AAX08_03360	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AAX08_03370	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AAX08_03390	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AAX08_03395	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AAX08_03400	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AAX08_03415	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
AAX08_03420	ENOG4105CFU	surface antigen
AAX08_03440	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AAX08_03445	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AAX08_03450	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AAX08_03455	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AAX08_03485	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AAX08_03500	ENOG4105C26	Dehydrogenase
AAX08_03510	ENOG4105C8P	)-transporter
AAX08_03520	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AAX08_03525	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AAX08_03530	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AAX08_03535	ENOG4105KNE	Phosphatidate cytidylyltransferase
AAX08_03540	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AAX08_03545	ENOG4105DZP	Membrane-associated zinc metalloprotease
AAX08_03550	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAX08_03555	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AAX08_03560	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AAX08_03565	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AAX08_03570	ENOG4105C8J	)-transporter
AAX08_03575	ENOG4105C8J	)-transporter
AAX08_03580	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AAX08_03590	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AAX08_03605	ENOG4105DHP	deoxycytidine triphosphate deaminase
AAX08_03620	ENOG4108UZE	carboxy-peptidase
AAX08_03625	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AAX08_03630	ENOG4105CSU	acyl-Coa dehydrogenase
AAX08_03640	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
AAX08_03650	ENOG4105FE9	pseudouridine synthase
AAX08_03655	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AAX08_03660	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AAX08_03665	ENOG4105C31	Tryptophanyl-tRNA synthetase
AAX08_03670	ENOG4105D7W	serine acetyltransferase
AAX08_03680	ENOG4105C0B	DNA polymerase III (alpha subunit)
AAX08_03685	ENOG4105DSY	exodeoxyribonuclease V, gamma
AAX08_03690	ENOG4107QKA	exodeoxyribonuclease V beta
AAX08_03695	ENOG4105C7H	Helicase, RecD TraA family
AAX08_03700	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AAX08_03705	ENOG4105W0E	50S ribosomal protein L33
AAX08_03710	ENOG4105KDC	50s ribosomal protein l28
AAX08_03720	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AAX08_03725	ENOG4105CFH	Aspartokinase
AAX08_03730	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AAX08_03735	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AAX08_03745	ENOG4107QTF	adenylosuccinate lyase
AAX08_03750	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AAX08_03780	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AAX08_03790	ENOG4105F5W	AtP-binding protein
AAX08_03810	ENOG41067XF	inhibitor
AAX08_03820	ENOG4105CKT	filamentous hemagglutinin
AAX08_03820	ENOG4105CKT	filamentous hemagglutinin
AAX08_03830	ENOG4105CKT	filamentous hemagglutinin
AAX08_03850	ENOG4105D5K	Hemolysin activator protein
AAX08_03865	ENOG4105M2J	Glutaredoxin
AAX08_03880	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AAX08_03895	ENOG4105EZE	Cupin 4 family protein
AAX08_03900	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AAX08_03915	ENOG4108Z66	YbaK ebsC protein
AAX08_03935	ENOG4105EYH	Exonuclease
AAX08_03940	ENOG4107RH8	nuclease SbcCD subunit D
AAX08_03950	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AAX08_03965	ENOG4105C5F	glutamine synthetase
AAX08_03970	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AAX08_03975	ENOG4105DWU	Membrane
AAX08_03980	ENOG4105D8X	mechanosensitive ion channel
AAX08_03990	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AAX08_03995	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AAX08_04010	ENOG4105C1J	atp-dependent rna helicase
AAX08_04015	ENOG4105CSA	Coproporphyrinogen iii oxidase
AAX08_04025	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AAX08_04045	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AAX08_04065	ENOG4106WTF	Glycosyl transferase, family 2
AAX08_04070	ENOG4108XM1	transcriptional regulator AsnC family
AAX08_04075	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AAX08_04100	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AAX08_04115	ENOG4107R11	Transcriptional regulator
AAX08_04120	ENOG4105EYM	Major Facilitator superfamily
AAX08_04125	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AAX08_04130	ENOG4105D06	uba thif-type nad fad binding protein
AAX08_04145	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
AAX08_04160	ENOG4105K8N	protein family UPF0079, ATPase
AAX08_04165	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AAX08_04170	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AAX08_04175	ENOG4105CHH	sulfate transporter
AAX08_04180	ENOG4107RZC	phospholipase d
AAX08_04185	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AAX08_04190	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AAX08_04195	ENOG4105K9H	YciI-like protein
AAX08_04210	ENOG4105D3Y	Na H antiporter
AAX08_04230	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AAX08_04235	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AAX08_04240	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AAX08_04250	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AAX08_04260	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AAX08_04265	ENOG4105CQC	Prephenate dehydratase
AAX08_04270	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AAX08_04275	ENOG4105FR1	rard protein
AAX08_04280	ENOG4107ZVW	dihydroneopterin aldolase
AAX08_04295	ENOG4105D1S	lipid A biosynthesis
AAX08_04300	ENOG4105C5H	ABC transporter
AAX08_04305	ENOG41069P5	Protein slyX homolog
AAX08_04315	ENOG4105DJV	ribulose-phosphate 3-epimerase
AAX08_04335	ENOG4105WH1	Two component transcriptional regulator luxr family
AAX08_04340	ENOG41061WM	D-Alanyl-D-Alanine
AAX08_04345	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AAX08_04350	ENOG4108JA2	transcriptioN-repair coupling factor
AAX08_04365	ENOG4105BZA	Phosphoglycerate kinase
AAX08_04375	ENOG4105D2N	Aldolase
AAX08_04380	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AAX08_04405	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AAX08_04420	ENOG4105SG9	biopolymer transport protein, ExbD
AAX08_04435	ENOG4105E09	nadh pyrophosphatase
AAX08_04440	ENOG4107RZZ	dna polymerase iii epsilon subunit
AAX08_04445	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AAX08_04455	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AAX08_04465	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
AAX08_04470	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AAX08_04475	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AAX08_04480	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AAX08_04490	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AAX08_04505	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
AAX08_04520	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AAX08_04530	ENOG4105C34	Pseudouridine synthase
AAX08_04545	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AAX08_04555	ENOG4105CQ7	ATP-dependent helicase
AAX08_04575	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AAX08_04605	ENOG4105CRK	lysyL-tRNA synthetase
AAX08_04615	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AAX08_04620	ENOG4105EXG	Transcriptional regulator
AAX08_04635	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AAX08_04640	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AAX08_04645	ENOG4108URH	decarboxylase
AAX08_04655	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AAX08_04660	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AAX08_04665	ENOG4105VIE	preprotein translocase, subunit YajC
AAX08_04670	ENOG4107RCQ	(CBS) domain
AAX08_04680	ENOG4105E9H	Lytic Murein transglycosylase
AAX08_04680	ENOG4105E9H	Lytic Murein transglycosylase
AAX08_04685	ENOG4107QNR	UPF0135 protein
AAX08_04690	ENOG4105C0H	protease
AAX08_04695	ENOG4105K3M	)-transporter
AAX08_04700	ENOG4105GNX	MltA-interacting MipA family protein
AAX08_04720	ENOG4107QSN	dihydrolipoamide acetyltransferase
AAX08_04725	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AAX08_04735	ENOG4108YRX	Iron-storage protein
AAX08_04745	ENOG4105EJQ	L-serine dehydratase
AAX08_04765	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AAX08_04770	ENOG4105CGK	Exodeoxyribonuclease III
AAX08_04775	ENOG4107YD3	Thioesterase
AAX08_04780	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AAX08_04795	ENOG4105ERU	peptidase
AAX08_04805	ENOG4105C9M	aspartyl-trna synthetase
AAX08_04825	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
AAX08_04830	ENOG4105C8Y	Acetylornithine aminotransferase
AAX08_04835	ENOG4107RZC	phospholipase d
AAX08_04840	ENOG4105CSH	Transporter
AAX08_04855	ENOG4105E66	phosphoriboisomerase A
AAX08_04865	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AAX08_04875	ENOG4105D6Z	AFG1 family ATPase
AAX08_04890	ENOG4105KVH	Transcriptional regulator
AAX08_04905	ENOG4105C2C	drug resistance transporter, Bcr CflA
AAX08_04910	ENOG4105C94	Transporter
AAX08_04925	ENOG4108JJ8	(ABC) transporter
AAX08_04930	ENOG4108JJ9	ABC, transporter
AAX08_04975	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AAX08_04985	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AAX08_04995	ENOG4105CDU	Replicative dna helicase
AAX08_05000	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AAX08_05005	ENOG4105DBV	ornithine carbamoyltransferase
AAX08_05020	ENOG4105C26	Dehydrogenase
AAX08_05025	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AAX08_05030	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AAX08_05035	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AAX08_05045	ENOG4105C7I	Dehydrogenase
AAX08_05050	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AAX08_05055	ENOG4108RCM	Nitroreductase
AAX08_05060	ENOG4105CN1	protease
AAX08_05065	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AAX08_05080	ENOG4105EIF	outer membrane protein W
AAX08_05085	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AAX08_05095	ENOG4105VCQ	rubredoxin
AAX08_05105	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
AAX08_05110	ENOG4105C12	Phosphoribosylglycinamide synthetase
AAX08_05115	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AAX08_05120	ENOG4105CSR	polyphosphate kinase 2
AAX08_05135	ENOG4105XPH	Ferredoxin
AAX08_05140	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AAX08_05155	ENOG4105C28	cystathionine
AAX08_05160	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AAX08_05165	ENOG4105DWK	Membrane
AAX08_05170	ENOG4107XM3	UPF0442 protein
AAX08_05180	ENOG4105BZS	acriflavin resistance protein
AAX08_05185	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AAX08_05220	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AAX08_05225	ENOG4108IUZ	ABC transporter
AAX08_05230	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AAX08_05240	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AAX08_05245	ENOG4105C2X	Arabinose 5-phosphate isomerase
AAX08_05250	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AAX08_05260	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
AAX08_05265	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AAX08_05270	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AAX08_05275	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AAX08_05285	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AAX08_05290	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AAX08_05295	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AAX08_05305	ENOG4105C59	p-type ATPase
AAX08_05315	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AAX08_05320	ENOG4105EUJ	GTP cyclohydrolase i
AAX08_05330	ENOG4105C9A	Phoh family
AAX08_05335	ENOG4107YVF	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AAX08_05340	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AAX08_05350	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AAX08_05355	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AAX08_05365	ENOG4105CAT	Cytidine monophosphate kinase
AAX08_05370	ENOG4108Z6B	deaminase
AAX08_05375	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AAX08_05400	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AAX08_05410	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
AAX08_05415	ENOG4105D64	Mechanosensitive ion channel
AAX08_05420	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AAX08_05430	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AAX08_05435	ENOG4105K3M	)-transporter
AAX08_05440	ENOG4105CHM	Aminotransferase
AAX08_05445	ENOG4105E0X	reductase
AAX08_05450	ENOG4108V06	Glutathione peroxidase
AAX08_05465	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AAX08_05470	ENOG4105DDQ	anthranilate synthase
AAX08_05475	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AAX08_05480	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AAX08_05485	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AAX08_05490	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AAX08_05495	ENOG410814C	multidrug resistance protein
AAX08_05500	ENOG4108IG5	Transcriptional regulator
AAX08_05505	ENOG4105C7N	Xanthine uracil vitamin C permease
AAX08_05510	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AAX08_05515	ENOG4105CPK	Glycosyl transferase (Group 1
AAX08_05520	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AAX08_05545	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AAX08_05555	ENOG4106CJB	Phospholipase Carboxylesterase
AAX08_05560	ENOG4105CGZ	zinc metallopeptidase
AAX08_05570	ENOG4108JQ5	ABC transporter
AAX08_05575	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AAX08_05580	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AAX08_05585	ENOG4107QSI	ABC, transporter
AAX08_05590	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AAX08_05595	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
AAX08_05600	ENOG4105D7N	magnesium and cobalt transport protein CorA
AAX08_05615	ENOG4105DR9	pseudouridine synthase
AAX08_05620	ENOG4107QRG	dna polymerase iii
AAX08_05625	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AAX08_05635	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AAX08_05640	ENOG4105BZ1	(ABC) transporter
AAX08_05645	ENOG4105FA0	parb-like partition protein
AAX08_05650	ENOG4107QJE	Chromosome Partitioning Protein
AAX08_05655	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AAX08_05660	ENOG4105DAN	ATP-dependent protease
AAX08_05710	ENOG4105C4W	S-formylglutathione hydrolase
AAX08_05725	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AAX08_05740	ENOG4105C4R	Atp-dependent dna helicase
AAX08_05755	ENOG4108TZV	Membrane
AAX08_05765	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AAX08_05775	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AAX08_05805	ENOG4105BZU	Histidine kinase
AAX08_05810	ENOG4108YZA	Nitrogen regulatory protein pii
AAX08_05815	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AAX08_05820	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AAX08_05830	ENOG4108WQI	RNA Polymerase
AAX08_05845	ENOG4105E18	UPF0276 protein
AAX08_05860	ENOG4107QN2	dihydrolipoyl dehydrogenase
AAX08_05880	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AAX08_05885	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AAX08_05895	ENOG4105CUT	histidyl-tRNA synthetase
AAX08_05915	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AAX08_05920	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AAX08_05925	ENOG4105C3G	gtp-binding protein
AAX08_05940	ENOG4105CGK	Exodeoxyribonuclease III
AAX08_05950	ENOG4105K5B	UPF0225 protein
AAX08_05970	ENOG4105DAA	L-lactate
AAX08_05980	ENOG4105DMF	Dehydrogenase
AAX08_05985	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AAX08_05990	ENOG4105K70	DNA-binding protein
AAX08_06000	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AAX08_06010	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AAX08_06015	ENOG4108Z4V	iron-sulfur cluster assembly
AAX08_06020	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
AAX08_06025	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AAX08_06030	ENOG4108ZIT	Ferredoxin, 2FE-2S
AAX08_06035	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AAX08_06040	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AAX08_06045	ENOG4105C02	permease
AAX08_06060	ENOG4105K46	50S ribosomal protein l27
AAX08_06065	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AAX08_06090	ENOG4105BZG	amino acid carrier protein
AAX08_06095	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AAX08_06100	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AAX08_06105	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AAX08_06115	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
AAX08_06120	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AAX08_06125	ENOG4105C2I	pirin domain protein
AAX08_06150	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AAX08_06155	ENOG4105EEI	dihydropteroate synthase
AAX08_06160	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AAX08_06175	ENOG4105FFC	UPF0187 protein
AAX08_06180	ENOG4108K5P	(LipO)protein
AAX08_06185	ENOG4105DM4	PTS System
AAX08_06190	ENOG4105DE4	1-phosphofructokinase
AAX08_06195	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AAX08_06205	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AAX08_06210	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AAX08_06215	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AAX08_06230	ENOG4108RWI	nicotinamidase
AAX08_06235	ENOG4105DP0	ferredoxin-NADP reductase
AAX08_06240	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAX08_06245	ENOG4105C8S	subunit m
AAX08_06250	ENOG4105D65	subunit l
AAX08_06255	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAX08_06265	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAX08_06270	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AAX08_06275	ENOG4108IEH	NADH dehydrogenase subunit g
AAX08_06280	ENOG4107QIZ	NADH dehydrogenase
AAX08_06285	ENOG4105GKE	subunit e
AAX08_06300	ENOG4105D7V	transposase
AAX08_06320	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAX08_06335	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAX08_06340	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AAX08_06345	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AAX08_06350	ENOG4105UYK	outer membrane protein a
AAX08_06360	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AAX08_06375	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AAX08_06400	ENOG4108UUM	single-stranded DNA-binding protein
AAX08_06595	ENOG4105F8V	Hydrolase, tatD family
AAX08_06600	ENOG4105D64	Mechanosensitive ion channel
AAX08_06605	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AAX08_06615	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AAX08_06620	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AAX08_06640	ENOG410863D	Flavinator of succinate dehydrogenase
AAX08_06665	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AAX08_06675	ENOG4105VUT	cytoplasmic protein
AAX08_06680	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AAX08_06690	ENOG4105C59	p-type ATPase
AAX08_06700	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AAX08_06705	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AAX08_06710	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AAX08_06725	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AAX08_06730	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AAX08_06735	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AAX08_06740	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AAX08_06745	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AAX08_06750	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AAX08_06760	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AAX08_06785	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AAX08_06790	ENOG4105D8T	Acyltransferase
AAX08_06805	ENOG4105ECY	inositol monophosphatase
AAX08_06810	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AAX08_06820	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AAX08_06830	ENOG4105D7V	transposase
AAX08_06840	ENOG4108MVK	Receptor
AAX08_06870	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AAX08_06875	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AAX08_06880	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AAX08_06895	ENOG4105DZR	Type I site-specific deoxyribonuclease
AAX08_06920	ENOG4108UVJ	appr-1-p processing domain protein
AAX08_06925	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AAX08_06930	ENOG4105EMU	Dehydrogenase
AAX08_06945	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AAX08_06950	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AAX08_06955	ENOG4107QUV	Domain protein
AAX08_06960	ENOG4105C26	Dehydrogenase
AAX08_06965	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AAX08_06970	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AAX08_06980	ENOG4108RMU	ferritin dps family protein
AAX08_07000	ENOG4105D49	3-dehydroquinate synthase
AAX08_07005	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AAX08_07010	ENOG4105E4G	Type IV pilus
AAX08_07045	ENOG4105DFA	alanine racemase domain protein
AAX08_07050	ENOG4105CZX	twitching motility protein
AAX08_07055	ENOG41090R7	Ferric uptake
AAX08_07060	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AAX08_07065	ENOG4105VDB	UPF0125 protein
AAX08_07075	ENOG4106RE7	Cytochrome
AAX08_07095	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AAX08_07100	ENOG4105KTH	gatB Yqey
AAX08_07105	ENOG4105ERG	peptidase m48, ste24p
AAX08_07110	ENOG4105VFE	sira family
AAX08_07115	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AAX08_07135	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AAX08_07140	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AAX08_07175	ENOG4108HED	Type II restriction
AAX08_07180	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AAX08_07190	ENOG4105K8R	UPF0145 protein
AAX08_07220	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AAX08_07230	ENOG4108YXA	Membrane
AAX08_07240	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AAX08_07245	ENOG4105CEY	Amp-dependent synthetase and ligase
AAX08_07250	ENOG4105CEY	Amp-dependent synthetase and ligase
AAX08_07260	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AAX08_07270	ENOG4105EJ9	Membrane
AAX08_07275	ENOG4105CK2	sodium dicarboxylate symporter
AAX08_07285	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AAX08_07310	ENOG4105CNG	UPF0061 protein
AAX08_07340	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AAX08_07350	ENOG4107QN1	sodium solute
AAX08_07360	ENOG4108KB2	LysR family Transcriptional regulator
AAX08_07365	ENOG4105CR4	methylisocitrate lyase
AAX08_07370	ENOG4105BZN	citrate synthase
AAX08_07380	ENOG4108I0Z	Aconitate hydratase
AAX08_07390	ENOG4105C7F	AcnD-accessory protein PrpF
AAX08_07400	ENOG4108JQC	penicillin-binding protein 1A
AAX08_07415	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AAX08_07420	ENOG4105CJR	Integral membrane protein (MviN
AAX08_07430	ENOG4108Z4U	Ferredoxin
AAX08_07435	ENOG4108SC4	)-transporter
AAX08_07450	ENOG4105BZG	amino acid carrier protein
AAX08_07455	ENOG4105C2W	permease
AAX08_07460	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AAX08_07480	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AAX08_07490	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AAX08_07495	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AAX08_07500	ENOG4105HBR	Rna-binding protein
AAX08_07520	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AAX08_07570	ENOG4105DFP	Integrase
AAX08_07580	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AAX08_07585	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AAX08_07590	ENOG4105CUZ	uba thif-type nad fad binding protein
AAX08_07595	ENOG4105EYA	deoxyribonuclease
AAX08_07650	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AAX08_07655	ENOG4105D6S	protein involved in catabolism of external DNA
AAX08_07675	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AAX08_07680	ENOG4107QKW	extracellular solute-binding protein family 1
AAX08_07695	ENOG4105CFC	Transporter
AAX08_07700	ENOG4105WVQ	Fe-S assembly protein IscX
AAX08_07705	ENOG4105WPN	DNA integration recombination invertion protein
AAX08_07710	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AAX08_07730	ENOG4105CH6	catalase
AAX08_07740	ENOG4105D1Q	UPF0246 protein
AAX08_07745	ENOG4108DNC	Involved in acetate metabolism (By similarity)
AAX08_07750	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AAX08_07755	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AAX08_07760	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AAX08_07780	ENOG4105UGU	tonB-dependent Receptor
AAX08_07785	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AAX08_07800	ENOG4105CFP	Peptidase U32
AAX08_07810	ENOG4105CQB	FAD linked oxidase domain protein
AAX08_07815	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AAX08_07820	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AAX08_07845	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AAX08_07850	ENOG4107S2Z	UPF0761 membrane protein
AAX08_07855	ENOG4105CD3	dihydroorotase
AAX08_07865	ENOG4105CXT	aspartate transcarbamylase
AAX08_07870	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AAX08_07885	ENOG4105C10	Electron transfer flavoprotein
AAX08_07890	ENOG4105BZJ	Electron transfer flavoprotein
AAX08_07895	ENOG4105VEQ	Cold shock protein
AAX08_07905	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AAX08_07920	ENOG4108ZP8	Acetolactate synthase small subunit
AAX08_07925	ENOG4105C7K	acetolactate synthase
AAX08_07935	ENOG4109066	lysm domain bon superfamily protein
AAX08_07945	ENOG4105CHR	reductase
AAX08_07950	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AAX08_07965	ENOG4108BPE	-transporting atpase
AAX08_07970	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AAX08_07975	ENOG4108ZT0	50S ribosomal protein l17
AAX08_07980	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AAX08_07985	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AAX08_07990	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AAX08_08000	ENOG41085ZR	50S ribosomal protein L36
AAX08_08005	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AAX08_08010	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AAX08_08015	ENOG4105VPB	50S ribosomal protein L30
AAX08_08025	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AAX08_08030	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AAX08_08035	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AAX08_08040	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AAX08_08045	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AAX08_08050	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AAX08_08055	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AAX08_08060	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AAX08_08070	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AAX08_08075	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AAX08_08080	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AAX08_08085	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AAX08_08090	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AAX08_08095	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AAX08_08100	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AAX08_08105	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AAX08_08110	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AAX08_08115	ENOG4105C03	ribonuclease
AAX08_08120	ENOG4108Z03	MAF-like protein
AAX08_08130	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AAX08_08135	ENOG4105WCN	acetyltransferase
AAX08_08140	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AAX08_08155	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AAX08_08160	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AAX08_08165	ENOG4105C0H	protease
AAX08_08190	ENOG4107S1Q	Phosphatase
AAX08_08195	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AAX08_08200	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AAX08_08220	ENOG4108UPT	UPF0178 protein
AAX08_08225	ENOG4105IPI	Membrane
AAX08_08240	ENOG4105CI0	Citrate lyase
AAX08_08255	ENOG4105D0D	Nitrate reductase 2, gamma subunit
AAX08_08260	ENOG4105R3A	Nitrate reductase
AAX08_08265	ENOG4108IUE	nitrate reductase beta subunit
AAX08_08270	ENOG4105CRU	nitrate reductase, alpha subunit
AAX08_08275	ENOG4108UUM	single-stranded DNA-binding protein
AAX08_08285	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AAX08_08290	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AAX08_08310	ENOG4105P8F	nudix hydrolase
AAX08_08315	ENOG4108JW7	Maf-like protein
AAX08_08320	ENOG4105DGW	oligopeptidase A
AAX08_08330	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AAX08_08340	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AAX08_08345	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AAX08_08355	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AAX08_08375	ENOG4105CRQ	synthase (Component I)
AAX08_08385	ENOG4105F27	Major Facilitator
AAX08_08395	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AAX08_08400	ENOG4108JU5	Magnesium and cobalt efflux protein
AAX08_08405	ENOG4108ZZ3	UPF0260 protein
AAX08_08415	ENOG4105CIN	aminoacyl-histidine dipeptidase
AAX08_08420	ENOG4108X4Q	Hydrolase
AAX08_08430	ENOG4105DC8	reductase
AAX08_08435	ENOG4108JQ1	Dehydrogenase
AAX08_08440	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AAX08_08445	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AAX08_08460	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AAX08_08465	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AAX08_08470	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AAX08_08485	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AAX08_08535	ENOG4105C2M	dna polymerase I
AAX08_08545	ENOG4105DHI	Methyltransferase
AAX08_08550	ENOG4105DQR	SNARE associated Golgi
AAX08_08560	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AAX08_08565	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AAX08_08575	ENOG4105CNU	cell division protein FtsK
AAX08_08580	ENOG4105C3M	thioredoxin reductase
AAX08_08590	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AAX08_08595	ENOG4105CBX	hi0933 family
AAX08_08600	ENOG4105ERG	peptidase m48, ste24p
AAX08_08605	ENOG4105M85	Bola protein
AAX08_08615	ENOG4105CHH	sulfate transporter
AAX08_08625	ENOG4105D3G	Pseudouridine synthase
AAX08_08630	ENOG4105K63	Thioredoxin
AAX08_08635	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AAX08_08650	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AAX08_08655	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AAX08_08660	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AAX08_08665	ENOG4105D7V	transposase
AAX08_08670	ENOG4105CDV	Ompa motb domain protein
AAX08_08705	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AAX08_08710	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AAX08_08720	ENOG4105DJ4	phosphatidylserine decarboxylase
AAX08_08730	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AAX08_08740	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AAX08_08750	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AAX08_08760	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
AAX08_08765	ENOG4107XDY	Nicotinamide Mononucleotide Transporter
AAX08_08775	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AAX08_08825	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AAX08_08840	ENOG4105D5K	Hemolysin activator protein
AAX08_08845	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
AAX08_08915	ENOG4105CKT	filamentous hemagglutinin
AAX08_08915	ENOG4105CKT	filamentous hemagglutinin
AAX08_08945	ENOG41067XF	inhibitor
AAX08_08985	ENOG4108MA7	Inherit from COG: YD repeat protein
AAX08_09025	ENOG4105UGU	tonB-dependent Receptor
AAX08_09030	ENOG4105F9F	transposase
AAX08_09040	ENOG4105CKT	filamentous hemagglutinin
AAX08_09065	ENOG4105E2B	Taurine dioxygenase
AAX08_09080	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AAX08_09095	ENOG4105D6U	Sodium Glutamate Symporter
AAX08_09100	ENOG4108ETH	Formylglycinamide ribotide synthetase
AAX08_09105	ENOG4105BZU	Histidine kinase
AAX08_09110	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AAX08_09130	ENOG4105C6T	cysteine synthase
AAX08_09135	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AAX08_09140	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AAX08_09150	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AAX08_09155	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AAX08_09160	ENOG4105T2N	Domain of unknown function (DUF2382)
AAX08_09175	ENOG4105CHV	Transcription elongation factor NusA
AAX08_09180	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AAX08_09195	ENOG4107EJC	Preprotein translocase subunit SecG
AAX08_09200	ENOG4105CP7	Triose-phosphate isomerase
AAX08_09205	ENOG4107QHF	type ii secretion system protein e
AAX08_09215	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AAX08_09220	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AAX08_09245	ENOG4105CB5	ATP-dependent DNA helicase recG
AAX08_09260	ENOG4108EKC	n-acetylglutamate synthase
AAX08_09270	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AAX08_09280	ENOG4105C5H	ABC transporter
AAX08_09295	ENOG4105CHU	acetyl-coa acetyltransferase
AAX08_09310	ENOG4105CRW	Short chain fatty acid transporter
AAX08_09320	ENOG4105CY2	Citrate transporter
AAX08_09325	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AAX08_09340	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AAX08_09345	ENOG4105C4X	radical SAM domain protein
AAX08_09350	ENOG4108RXX	maleylacetoacetate isomerase
AAX08_09365	ENOG4105DND	Transcriptional regulator
AAX08_09370	ENOG4107RZC	phospholipase d
AAX08_09375	ENOG4105MIR	Phenylalanine 4-monooxygenase
AAX08_09380	ENOG41090A4	Pterin carbinolamine dehydratase
AAX08_09385	ENOG4105DFD	Na H antiporter
AAX08_09400	ENOG4105DND	Transcriptional regulator
AAX08_09425	ENOG4105ETU	transcriptional activator (TenA
AAX08_09430	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AAX08_09445	ENOG4105C8V	SAICAR synthetase
AAX08_09455	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AAX08_09460	ENOG4105C0H	protease
AAX08_09465	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AAX08_09470	ENOG4105HHA	aminodeoxychorismate lyase
AAX08_09485	ENOG4105E2X	shikimate dehydrogenase
AAX08_09490	ENOG4105CSU	acyl-Coa dehydrogenase
AAX08_09500	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AAX08_09510	ENOG4106PMH	Extracellular solute-binding protein family 3
AAX08_09515	ENOG4106PMH	Extracellular solute-binding protein family 3
AAX08_09520	ENOG4106TNF	Periplasmic binding protein
AAX08_09560	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AAX08_09570	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
AAX08_09585	ENOG4105D7T	ABC transporter
AAX08_09595	ENOG4105X23	Endonuclease Exonuclease phosphatase
AAX08_09605	ENOG4105DGW	oligopeptidase A
AAX08_09615	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AAX08_09625	ENOG4105C29	acyl-CoA thioesterase
AAX08_09630	ENOG4107QS8	(LipO)protein
AAX08_09635	ENOG4105CKI	cobalamin synthesis protein
AAX08_09645	ENOG4105C37	(CBS) domain
AAX08_09650	ENOG4105UBK	short-chain dehydrogenase reductase
AAX08_09655	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AAX08_09660	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AAX08_09665	ENOG4108Z33	Thiol disulfide Interchange Protein
AAX08_09670	ENOG4105N42	UPF0307 protein
AAX08_09675	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AAX08_09680	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AAX08_09685	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AAX08_09690	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AAX08_09695	ENOG4105DJ0	Poly(A) Polymerase
AAX08_09700	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AAX08_09705	ENOG4105DXN	mazG family
AAX08_09710	ENOG4105C6T	cysteine synthase
AAX08_09720	ENOG4105ETT	transcriptional Regulator, LysR family
AAX08_09725	ENOG4105C1G	acyl-Coa dehydrogenase
AAX08_09730	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AAX08_09760	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AAX08_09795	ENOG4105IPS	esterase
AAX08_09830	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AAX08_09835	ENOG4105D9M	gamma-glutamylcysteine synthetase
AAX08_09840	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AAX08_09845	ENOG4105DFU	Cell wall formation (By similarity)
AAX08_09855	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AAX08_09860	ENOG4105CH7	arginosuccinase
AAX08_09870	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AAX08_09885	ENOG4105CFG	Acts as a chaperone (By similarity)
AAX08_09890	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AAX08_09900	ENOG4105DKK	Benzoate
AAX08_09935	ENOG4105EB3	Histidine kinase
AAX08_09950	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AAX08_09955	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AAX08_09960	ENOG4108UJU	UPF0301 protein
AAX08_09965	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AAX08_09975	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AAX08_09980	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AAX08_09985	ENOG4107Y49	methyltransferase
AAX08_10000	ENOG4105CEY	Amp-dependent synthetase and ligase
AAX08_10005	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AAX08_10015	ENOG4105C1G	acyl-Coa dehydrogenase
AAX08_10085	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
AAX08_10090	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AAX08_10105	ENOG4105C79	DNA protecting protein DprA
AAX08_10115	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AAX08_10130	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AAX08_10135	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AAX08_10140	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AAX08_10145	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AAX08_10150	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AAX08_10155	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AAX08_10160	ENOG4105VG0	50S ribosomal protein l34