locus-tag	class	description
AAX08_00010	COG0592	DNA-directed DNA polymerase activity
AAX08_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AAX08_00020	COG0187	DNA topoisomerase II activity
AAX08_00025	COG0519	Catalyzes the synthesis of GMP from XMP
AAX08_00025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AAX08_00035	COG0251	oxidation-reduction process
AAX08_00050	COG1132	(ABC) transporter
AAX08_00055	COG0242	peptide deformylase activity
AAX08_00060	COG0131	Imidazoleglycerol-phosphate dehydratase
AAX08_00065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AAX08_00070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AAX08_00080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AAX08_00125	COG0488	(ABC) transporter
AAX08_00130	COG0484	heat shock protein binding
AAX08_00135	COG0429	hydrolase of the alpha beta-hydrolase fold
AAX08_00140	COG1408	metallophosphoesterase
AAX08_00145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AAX08_00150	COG0484	heat shock protein binding
AAX08_00170	COG1739	Uncharacterized protein family UPF0029
AAX08_00180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAX08_00195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AAX08_00200	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AAX08_00225	COG0583	DNA-binding transcription factor activity
AAX08_00230	COG1448	Aminotransferase
AAX08_00235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AAX08_00245	COG0795	lipopolysaccharide-transporting ATPase activity
AAX08_00250	COG0745	RESPONSE REGULATOR receiver
AAX08_00255	COG2183	response to ionizing radiation
AAX08_00265	COG2009	succinate dehydrogenase
AAX08_00270	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AAX08_00275	COG1053	succinate dehydrogenase
AAX08_00360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AAX08_00365	COG0166	Belongs to the GPI family
AAX08_00370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AAX08_00385	COG4269	membrane
AAX08_00395	COG0544	peptidyl-prolyl cis-trans isomerase activity
AAX08_00400	COG0740	serine-type endopeptidase activity
AAX08_00405	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AAX08_00410	COG1250	3-hydroxyacyl-CoA dehydrogenase
AAX08_00410	COG1024	Enoyl-CoA hydratase
AAX08_00415	COG0183	Belongs to the thiolase family
AAX08_00425	COG4607	ABC-type enterochelin transport system periplasmic component
AAX08_00435	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAX08_00440	COG4605	iron ion homeostasis
AAX08_00450	COG4604	ABC transporter, ATP-binding protein
AAX08_00455	COG4145	pantothenate transmembrane transporter activity
AAX08_00460	COG3924	membrane
AAX08_00475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AAX08_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AAX08_00495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAX08_00500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAX08_00505	COG0140	phosphoribosyl-ATP diphosphatase activity
AAX08_00505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AAX08_00520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AAX08_00530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AAX08_00535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAX08_00535	COG0072	phenylalanine-tRNA ligase activity
AAX08_00540	COG0776	regulation of translation
AAX08_00545	COG0254	rRNA binding
AAX08_00555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AAX08_00570	COG1522	sequence-specific DNA binding
AAX08_00575	COG2962	Rard protein
AAX08_00580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AAX08_00590	COG1116	anion transmembrane transporter activity
AAX08_00595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAX08_00600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AAX08_00605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AAX08_00610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AAX08_00670	COG0481	GTPase activity
AAX08_00680	COG0571	ribonuclease III activity
AAX08_00685	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AAX08_00695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AAX08_00700	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AAX08_00700	COG2885	chlorophyll binding
AAX08_00725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AAX08_00730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AAX08_00735	COG0513	Belongs to the DEAD box helicase family
AAX08_00745	COG2832	Protein of unknown function (DUF454)
AAX08_00760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AAX08_00770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AAX08_00785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAX08_00790	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AAX08_00795	COG0107	imidazoleglycerol-phosphate synthase activity
AAX08_00805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AAX08_00810	COG0121	glutamine amidotransferase
AAX08_00815	COG4106	trans-aconitate 2-methyltransferase activity
AAX08_00850	COG0326	Molecular chaperone. Has ATPase activity
AAX08_00870	COG0277	FAD linked oxidase domain protein
AAX08_00885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAX08_00890	COG0275	rRNA processing
AAX08_00910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AAX08_00915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AAX08_00920	COG1024	Enoyl-CoA hydratase
AAX08_00925	COG2814	Major facilitator Superfamily
AAX08_00930	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AAX08_00935	COG1714	RDD family
AAX08_00940	COG0792	nuclease activity
AAX08_00955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AAX08_00960	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AAX08_00965	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AAX08_00970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AAX08_00975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AAX08_00975	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AAX08_00980	COG1530	ribonuclease E activity
AAX08_00990	COG0248	Ppx GppA phosphatase
AAX08_01000	COG0037	tRNA processing
AAX08_01005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AAX08_01015	COG0352	thiamine-phosphate diphosphorylase activity
AAX08_01015	COG0351	phosphomethylpyrimidine kinase
AAX08_01015	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AAX08_01045	COG0193	aminoacyl-tRNA hydrolase activity
AAX08_01050	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AAX08_01055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAX08_01060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AAX08_01075	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AAX08_01090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AAX08_01100	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AAX08_01110	COG0582	viral genome integration into host DNA
AAX08_01165	COG0586	Pfam SNARE associated Golgi protein
AAX08_01185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AAX08_01190	COG0024	Methionine aminopeptidase
AAX08_01195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAX08_01195	COG3453	Protein conserved in bacteria
AAX08_01200	COG1902	pentaerythritol trinitrate reductase activity
AAX08_01200	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAX08_01215	COG3161	chorismate lyase activity
AAX08_01235	COG1227	inorganic diphosphatase activity
AAX08_01240	COG1472	Belongs to the glycosyl hydrolase 3 family
AAX08_01245	COG0793	Belongs to the peptidase S41A family
AAX08_01250	COG2205	protein histidine kinase activity
AAX08_01255	COG0745	RESPONSE REGULATOR receiver
AAX08_01265	COG3038	cytochrome b561
AAX08_01270	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AAX08_01310	COG0450	alkyl hydroperoxide reductase
AAX08_01315	COG2841	Protein conserved in bacteria
AAX08_01320	COG3634	alkyl hydroperoxide reductase activity
AAX08_01330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AAX08_01340	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AAX08_01340	COG0644	oxidoreductase
AAX08_01350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AAX08_01360	COG2951	lytic endotransglycosylase activity
AAX08_01370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AAX08_01380	COG0521	Mo-molybdopterin cofactor biosynthetic process
AAX08_01385	COG0746	molybdenum cofactor guanylyltransferase activity
AAX08_01390	COG0315	cyclic pyranopterin monophosphate synthase activity
AAX08_01395	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AAX08_01400	COG0314	molybdopterin synthase activity
AAX08_01405	COG0725	ABC transporter, periplasmic molybdate-binding protein
AAX08_01410	COG4149	molybdate abc transporter
AAX08_01420	COG0288	reversible hydration of carbon dioxide
AAX08_01430	COG2197	response regulator
AAX08_01435	COG3850	Histidine kinase
AAX08_01445	COG2223	nitrite transmembrane transporter activity
AAX08_01455	COG0754	glutathionylspermidine amidase activity
AAX08_01475	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AAX08_01480	COG1464	Belongs to the NlpA lipoprotein family
AAX08_01495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AAX08_01510	COG0606	chelatase, subunit chli
AAX08_01515	COG0546	phosphoglycolate phosphatase activity
AAX08_01530	COG0142	geranyltranstransferase activity
AAX08_01535	COG1194	a g-specific adenine glycosylase
AAX08_01555	COG0347	Belongs to the P(II) protein family
AAX08_01560	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AAX08_01565	COG0772	Belongs to the SEDS family
AAX08_01570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAX08_01575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AAX08_01585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AAX08_01590	COG1121	(ABC) transporter
AAX08_01595	COG0735	belongs to the Fur family
AAX08_01610	COG0356	it plays a direct role in the translocation of protons across the membrane
AAX08_01620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AAX08_01625	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAX08_01630	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AAX08_01635	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AAX08_01640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AAX08_01645	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AAX08_01650	COG0745	RESPONSE REGULATOR receiver
AAX08_01655	COG2205	protein histidine kinase activity
AAX08_01660	COG2205	protein histidine kinase activity
AAX08_01665	COG0228	four-way junction DNA binding
AAX08_01670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AAX08_01675	COG0336	Belongs to the RNA methyltransferase TrmD family
AAX08_01680	COG0335	large ribosomal subunit rRNA binding
AAX08_01690	COG0322	excinuclease ABC activity
AAX08_01700	COG0492	ferredoxin-NADP+ reductase activity
AAX08_01725	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AAX08_01730	COG0494	nUDIX hydrolase
AAX08_01735	COG1765	OsmC-like protein
AAX08_01745	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AAX08_01755	COG0730	response to heat
AAX08_01765	COG0629	single-stranded DNA binding
AAX08_01775	COG1196	nuclear chromosome segregation
AAX08_01780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAX08_01785	COG4106	trans-aconitate 2-methyltransferase activity
AAX08_01790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAX08_01805	COG2354	Protein conserved in bacteria
AAX08_01815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AAX08_01840	COG0672	)-iron permease
AAX08_01855	COG2871	sodium ion transport
AAX08_01860	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AAX08_01865	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AAX08_01870	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AAX08_01880	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AAX08_01885	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AAX08_01895	COG0557	exoribonuclease II activity
AAX08_01915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AAX08_01930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AAX08_01935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AAX08_01975	COG0052	Belongs to the universal ribosomal protein uS2 family
AAX08_01980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AAX08_01990	COG0189	ligase activity
AAX08_02000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AAX08_02005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AAX08_02015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AAX08_02025	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AAX08_02060	COG1505	serine-type exopeptidase activity
AAX08_02085	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AAX08_02090	COG0849	cell division
AAX08_02100	COG0613	PHP domain protein
AAX08_02105	COG2137	regulation of response to DNA damage stimulus
AAX08_02110	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AAX08_02115	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AAX08_02130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AAX08_02145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AAX08_02150	COG1758	RNA polymerase activity
AAX08_02155	COG0602	queuosine metabolic process
AAX08_02160	COG2171	N-acyltransferase activity
AAX08_02180	COG1914	H( )-stimulated, divalent metal cation uptake system
AAX08_02190	COG1984	allophanate hydrolase subunit 2
AAX08_02195	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AAX08_02200	COG0439	Biotin carboxylase
AAX08_02205	COG0511	ligase activity, forming carbon-carbon bonds
AAX08_02210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AAX08_02275	COG0300	oxidoreductase activity
AAX08_02305	COG1518	maintenance of DNA repeat elements
AAX08_02315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AAX08_02330	COG0076	glutamate decarboxylase activity
AAX08_02345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAX08_02345	COG2813	Specifically methylates the guanine in position
AAX08_02350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAX08_02355	COG4172	Belongs to the ABC transporter superfamily
AAX08_02360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAX08_02365	COG0601	transmembrane transport
AAX08_02375	COG0747	negative chemotaxis
AAX08_02380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AAX08_02395	COG0194	GDP metabolic process
AAX08_02410	COG0583	DNA-binding transcription factor activity
AAX08_02420	COG0531	amino acid
AAX08_02425	COG1028	Short-chain dehydrogenase reductase Sdr
AAX08_02440	COG1755	Isoprenylcysteine carboxyl methyltransferase
AAX08_02455	COG2255	four-way junction helicase activity
AAX08_02500	COG2885	chlorophyll binding
AAX08_02505	COG0308	aminopeptidase N
AAX08_02510	COG1519	Transferase
AAX08_02515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AAX08_02520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAX08_02625	COG0196	riboflavin kinase activity
AAX08_02635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AAX08_02640	COG1196	nuclear chromosome segregation
AAX08_02640	COG0741	lytic transglycosylase activity
AAX08_02640	COG0739	heme binding
AAX08_02645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAX08_02655	COG0215	cysteine-tRNA ligase activity
AAX08_02685	COG1131	(ABC) transporter
AAX08_02690	COG0842	Transport permease protein
AAX08_02695	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AAX08_02695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AAX08_02705	COG1666	GTP binding
AAX08_02720	COG2274	protein secretion by the type I secretion system
AAX08_02755	COG1376	ErfK ybiS ycfS ynhG family protein
AAX08_02775	COG0348	domain, Protein
AAX08_02800	COG3278	Belongs to the heme-copper respiratory oxidase family
AAX08_02815	COG2010	Cytochrome c
AAX08_02830	COG1136	(ABC) transporter
AAX08_02840	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AAX08_02850	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AAX08_02860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AAX08_02875	COG1162	GTPase activity
AAX08_02890	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AAX08_02895	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AAX08_02900	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AAX08_02905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AAX08_02915	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AAX08_02925	COG0018	arginyl-trna synthetase
AAX08_02935	COG0573	inorganic phosphate transmembrane transporter activity
AAX08_02940	COG0581	inorganic phosphate transmembrane transporter activity
AAX08_02945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AAX08_02955	COG5002	protein histidine kinase activity
AAX08_02970	COG0217	transcriptional regulatory protein
AAX08_02980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AAX08_02995	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAX08_03010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAX08_03015	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AAX08_03040	COG0577	efflux transmembrane transporter activity
AAX08_03040	COG1136	(ABC) transporter
AAX08_03055	COG0495	leucyl-tRNA aminoacylation
AAX08_03060	COG1393	Belongs to the ArsC family
AAX08_03075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AAX08_03080	COG0756	dUTP diphosphatase activity
AAX08_03095	COG1346	cytolysis
AAX08_03100	COG0501	Belongs to the peptidase M48B family
AAX08_03115	COG0583	DNA-binding transcription factor activity
AAX08_03120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AAX08_03125	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AAX08_03130	COG3178	'Phosphotransferase
AAX08_03135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AAX08_03150	COG0697	spore germination
AAX08_03155	COG0697	spore germination
AAX08_03160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAX08_03160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAX08_03170	COG0625	glutathione transferase activity
AAX08_03185	COG2857	Cytochrome c1
AAX08_03190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AAX08_03195	COG0723	plastoquinol--plastocyanin reductase activity
AAX08_03200	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AAX08_03205	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AAX08_03210	COG0742	ribosomal rna small subunit methyltransferase
AAX08_03240	COG0563	adenylate kinase activity
AAX08_03250	COG0537	adenosine 5'-monophosphoramidase activity
AAX08_03265	COG1720	tRNA m6t6A37 methyltransferase activity
AAX08_03280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AAX08_03285	COG1966	Carbon starvation protein
AAX08_03290	COG0183	Belongs to the thiolase family
AAX08_03295	COG1028	Short-chain dehydrogenase reductase Sdr
AAX08_03315	COG0129	dihydroxy-acid dehydratase activity
AAX08_03325	COG0628	permease
AAX08_03330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AAX08_03340	COG1114	Component of the transport system for branched-chain amino acids
AAX08_03345	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AAX08_03345	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AAX08_03350	COG0509	glycine decarboxylation via glycine cleavage system
AAX08_03355	COG1028	Short-chain dehydrogenase reductase Sdr
AAX08_03360	COG0509	glycine decarboxylation via glycine cleavage system
AAX08_03380	COG3100	YcgL domain-containing protein
AAX08_03390	COG0360	Binds together with S18 to 16S ribosomal RNA
AAX08_03395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AAX08_03400	COG0359	binds to the 23S rRNA
AAX08_03415	COG2814	Major facilitator Superfamily
AAX08_03420	COG0729	surface antigen
AAX08_03440	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AAX08_03445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AAX08_03450	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AAX08_03485	COG0321	lipoyl(octanoyl) transferase activity
AAX08_03510	COG0471	metal ion transport
AAX08_03520	COG0528	UMP kinase activity
AAX08_03525	COG0233	cytoplasmic translational termination
AAX08_03530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AAX08_03535	COG0575	Belongs to the CDS family
AAX08_03540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AAX08_03555	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAX08_03560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AAX08_03565	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAX08_03570	COG0733	neurotransmitter:sodium symporter activity
AAX08_03575	COG0733	neurotransmitter:sodium symporter activity
AAX08_03580	COG0343	queuine tRNA-ribosyltransferase activity
AAX08_03590	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AAX08_03600	COG0489	protein tyrosine kinase activity
AAX08_03605	COG0717	Belongs to the dCTP deaminase family
AAX08_03620	COG1876	peptidase activity
AAX08_03625	COG0585	pseudouridine synthase activity
AAX08_03630	COG1960	acyl-CoA dehydrogenase activity
AAX08_03640	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AAX08_03655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AAX08_03660	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AAX08_03670	COG1045	serine acetyltransferase
AAX08_03685	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AAX08_03690	COG1074	ATP-dependent DNA helicase activity
AAX08_03695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AAX08_03705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AAX08_03710	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AAX08_03720	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AAX08_03725	COG0527	aspartate kinase activity
AAX08_03730	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AAX08_03735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AAX08_03750	COG0482	sulfurtransferase activity
AAX08_03780	COG1518	maintenance of DNA repeat elements
AAX08_03790	COG1484	DNA-dependent DNA replication
AAX08_03810	COG2732	(Barnase) inhibitor
AAX08_03820	COG3210	domain, Protein
AAX08_03820	COG3210	domain, Protein
AAX08_03850	COG2831	hemolysin activation secretion protein
AAX08_03865	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AAX08_03880	COG0445	tRNA wobble uridine modification
AAX08_03895	COG2850	peptidyl-arginine hydroxylation
AAX08_03900	COG2890	protein-(glutamine-N5) methyltransferase activity
AAX08_03915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AAX08_03935	COG0419	ATPase involved in DNA repair
AAX08_03940	COG0420	3'-5' exonuclease activity
AAX08_03970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AAX08_03975	COG2431	L-lysine efflux transmembrane transporter activity
AAX08_03980	COG0668	transmembrane transport
AAX08_03990	COG0037	tRNA processing
AAX08_03995	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AAX08_04000	COG1278	Cold shock
AAX08_04010	COG0513	Belongs to the DEAD box helicase family
AAX08_04015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AAX08_04025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AAX08_04045	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AAX08_04065	COG0463	Glycosyl transferase, family 2
AAX08_04070	COG1522	sequence-specific DNA binding
AAX08_04075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AAX08_04100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AAX08_04115	COG0583	DNA-binding transcription factor activity
AAX08_04120	COG2211	Major facilitator Superfamily
AAX08_04125	COG2890	protein-(glutamine-N5) methyltransferase activity
AAX08_04130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AAX08_04135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AAX08_04145	COG0019	diaminopimelate decarboxylase activity
AAX08_04160	COG0802	atpase or kinase
AAX08_04165	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AAX08_04170	COG1923	regulation of RNA biosynthetic process
AAX08_04175	COG0659	secondary active sulfate transmembrane transporter activity
AAX08_04180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAX08_04185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AAX08_04190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AAX08_04190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAX08_04195	COG2350	Protein conserved in bacteria
AAX08_04210	COG2056	Na+-H+ antiporter family
AAX08_04220	COG0612	Peptidase, M16
AAX08_04230	COG0552	protein localization to endoplasmic reticulum
AAX08_04235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AAX08_04240	COG0167	dihydroorotate dehydrogenase activity
AAX08_04260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AAX08_04270	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AAX08_04280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AAX08_04295	COG1560	Kdo2-lipid A biosynthetic process
AAX08_04305	COG2900	Belongs to the SlyX family
AAX08_04315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AAX08_04340	COG1686	Belongs to the peptidase S11 family
AAX08_04345	COG0352	thiamine-phosphate diphosphorylase activity
AAX08_04350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AAX08_04360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AAX08_04365	COG0126	phosphoglycerate kinase activity
AAX08_04375	COG0191	fructose-bisphosphate aldolase activity
AAX08_04380	COG0632	four-way junction helicase activity
AAX08_04385	COG0583	DNA-binding transcription factor activity
AAX08_04440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AAX08_04445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AAX08_04455	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AAX08_04470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AAX08_04475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AAX08_04480	COG0268	Binds directly to 16S ribosomal RNA
AAX08_04505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AAX08_04520	COG0358	DNA primase activity
AAX08_04530	COG0564	pseudouridine synthase activity
AAX08_04545	COG0823	Involved in the tonB-independent uptake of proteins
AAX08_04555	COG1643	Atp-dependent helicase
AAX08_04575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AAX08_04605	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AAX08_04635	COG0439	Biotin carboxylase
AAX08_04640	COG0511	ligase activity, forming carbon-carbon bonds
AAX08_04665	COG1862	Preprotein translocase
AAX08_04670	COG1253	flavin adenine dinucleotide binding
AAX08_04680	COG0741	lytic transglycosylase activity
AAX08_04680	COG1388	LysM domain
AAX08_04680	COG0741	lytic transglycosylase activity
AAX08_04680	COG1388	LysM domain
AAX08_04685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AAX08_04690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AAX08_04700	COG3713	MltA-interacting MipA family protein
AAX08_04705	COG0625	glutathione transferase activity
AAX08_04720	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAX08_04745	COG1760	l-serine dehydratase
AAX08_04765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AAX08_04770	COG0708	Exodeoxyribonuclease III
AAX08_04775	COG0824	Thioesterase
AAX08_04780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AAX08_04785	COG0390	transport system, permease component
AAX08_04795	COG0616	signal peptide processing
AAX08_04805	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AAX08_04825	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AAX08_04830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AAX08_04835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAX08_04840	COG0477	Major facilitator Superfamily
AAX08_04855	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AAX08_04865	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AAX08_04875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AAX08_04890	COG1733	regulation of RNA biosynthetic process
AAX08_04905	COG2814	Major facilitator Superfamily
AAX08_04910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AAX08_04925	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AAX08_04930	COG4988	ABC transporter
AAX08_04975	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AAX08_04985	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AAX08_04995	COG0305	Participates in initiation and elongation during chromosome replication
AAX08_05000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AAX08_05005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AAX08_05025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAX08_05030	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AAX08_05035	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AAX08_05050	COG1570	exodeoxyribonuclease VII activity
AAX08_05060	COG0793	Belongs to the peptidase S41A family
AAX08_05065	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AAX08_05080	COG3047	cAMP biosynthetic process
AAX08_05085	COG0556	nucleotide-excision repair
AAX08_05095	COG1773	rubredoxin
AAX08_05105	COG0179	Fumarylacetoacetate (FAA) hydrolase
AAX08_05135	COG0633	Ferredoxin
AAX08_05140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAX08_05165	COG2966	Psort location CytoplasmicMembrane, score
AAX08_05170	COG3610	response to peptide
AAX08_05185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAX08_05225	COG1137	ATPase activity
AAX08_05230	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AAX08_05240	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AAX08_05245	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AAX08_05245	COG0517	IMP dehydrogenase activity
AAX08_05250	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AAX08_05260	COG0742	ribosomal rna small subunit methyltransferase
AAX08_05265	COG1968	undecaprenyl-diphosphatase activity
AAX08_05270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AAX08_05275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AAX08_05285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AAX08_05290	COG0542	response to heat
AAX08_05295	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AAX08_05305	COG2217	Heavy metal translocating P-type atpase
AAX08_05315	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AAX08_05330	COG1702	phosphate starvation-inducible protein PhoH
AAX08_05335	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AAX08_05340	COG0284	orotidine-5'-phosphate decarboxylase activity
AAX08_05350	COG0776	regulation of translation
AAX08_05365	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AAX08_05370	COG0590	tRNA wobble adenosine to inosine editing
AAX08_05375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AAX08_05400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AAX08_05410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAX08_05415	COG0668	transmembrane transport
AAX08_05420	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AAX08_05420	COG1648	precorrin-2 dehydrogenase activity
AAX08_05430	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AAX08_05440	COG0436	Aminotransferase
AAX08_05445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAX08_05450	COG0386	Belongs to the glutathione peroxidase family
AAX08_05465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AAX08_05470	COG0512	Glutamine amidotransferase of anthranilate synthase
AAX08_05475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AAX08_05480	COG0134	indole-3-glycerol-phosphate synthase activity
AAX08_05485	COG2095	MarC family integral membrane protein
AAX08_05490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AAX08_05505	COG2252	PERMEase
AAX08_05510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AAX08_05515	COG0438	transferase activity, transferring glycosyl groups
AAX08_05545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AAX08_05555	COG0400	carboxylic ester hydrolase activity
AAX08_05560	COG2321	neutral zinc metallopeptidase
AAX08_05570	COG4172	Belongs to the ABC transporter superfamily
AAX08_05575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAX08_05580	COG0601	transmembrane transport
AAX08_05590	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AAX08_05595	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AAX08_05600	COG0598	Magnesium transport protein CorA
AAX08_05625	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AAX08_05635	COG1663	tetraacyldisaccharide 4'-kinase activity
AAX08_05640	COG1132	(ABC) transporter
AAX08_05645	COG1475	DNA binding
AAX08_05650	COG1192	Involved in chromosome partitioning
AAX08_05655	COG0357	Ribosomal RNA small subunit methyltransferase G
AAX08_05660	COG1067	ATP-dependent peptidase activity
AAX08_05725	COG1902	pentaerythritol trinitrate reductase activity
AAX08_05740	COG0210	DNA helicase
AAX08_05755	COG0697	spore germination
AAX08_05765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AAX08_05775	COG1136	(ABC) transporter
AAX08_05775	COG0577	efflux transmembrane transporter activity
AAX08_05785	COG0697	spore germination
AAX08_05805	COG0004	ammonium transporteR
AAX08_05810	COG0347	Belongs to the P(II) protein family
AAX08_05815	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAX08_05820	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AAX08_05830	COG1595	DNA-templated transcription, initiation
AAX08_05835	COG2259	Doxx family
AAX08_05845	COG3220	belongs to the UPF0276 family
AAX08_05860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAX08_05880	COG1160	GTP binding
AAX08_05885	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAX08_05895	COG0124	histidyl-tRNA synthetase
AAX08_05915	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AAX08_05920	COG0105	UTP biosynthetic process
AAX08_05940	COG0708	Exodeoxyribonuclease III
AAX08_05950	COG3012	SEC-C Motif Domain Protein
AAX08_05970	COG1620	l-lactate permease
AAX08_05980	COG1304	FMN binding
AAX08_05985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AAX08_06000	COG1959	2 iron, 2 sulfur cluster binding
AAX08_06010	COG0822	iron-sulfur transferase activity
AAX08_06015	COG0316	Belongs to the HesB IscA family
AAX08_06020	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AAX08_06025	COG0443	Heat shock 70 kDa protein
AAX08_06035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AAX08_06040	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AAX08_06045	COG0628	permease
AAX08_06060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AAX08_06065	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AAX08_06090	COG1115	amino acid carrier protein
AAX08_06100	COG1294	oxidase, subunit
AAX08_06120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AAX08_06120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AAX08_06125	COG1741	Belongs to the pirin family
AAX08_06150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AAX08_06155	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AAX08_06160	COG1234	tRNA 3'-trailer cleavage
AAX08_06175	COG3781	membrane
AAX08_06180	COG4942	peptidase
AAX08_06185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AAX08_06185	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AAX08_06185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AAX08_06190	COG1105	Belongs to the carbohydrate kinase PfkB family
AAX08_06205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AAX08_06215	COG0505	Belongs to the CarA family
AAX08_06230	COG1335	isochorismatase
AAX08_06235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AAX08_06240	COG1007	ATP synthesis coupled electron transport
AAX08_06245	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAX08_06255	COG0713	ATP synthesis coupled electron transport
AAX08_06265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAX08_06270	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AAX08_06275	COG1034	ATP synthesis coupled electron transport
AAX08_06280	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AAX08_06300	COG0675	Transposase, IS605 OrfB family
AAX08_06320	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAX08_06320	COG0649	NAD binding
AAX08_06335	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAX08_06340	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAX08_06345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AAX08_06360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AAX08_06400	COG0629	single-stranded DNA binding
AAX08_06595	COG0084	hydrolase, TatD family'
AAX08_06600	COG0668	transmembrane transport
AAX08_06605	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AAX08_06615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AAX08_06620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AAX08_06640	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AAX08_06665	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AAX08_06675	COG3139	Protein of unknown function (DUF1315)
AAX08_06680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AAX08_06690	COG2217	Heavy metal translocating P-type atpase
AAX08_06700	COG2264	protein methyltransferase activity
AAX08_06710	COG0138	bifunctional purine biosynthesis protein purh
AAX08_06725	COG0658	competence protein
AAX08_06725	COG2333	competence protein COMEC
AAX08_06730	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AAX08_06735	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AAX08_06740	COG0148	phosphopyruvate hydratase activity
AAX08_06745	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AAX08_06750	COG0504	CTP synthase activity
AAX08_06760	COG2818	Glycosylase
AAX08_06785	COG2022	thiamine diphosphate biosynthetic process
AAX08_06790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AAX08_06810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AAX08_06820	COG0408	coproporphyrinogen oxidase activity
AAX08_06830	COG0675	Transposase, IS605 OrfB family
AAX08_06840	COG4771	TonB-dependent receptor
AAX08_06840	COG1629	transport
AAX08_06870	COG0285	dihydrofolate synthase activity
AAX08_06875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AAX08_06880	COG0159	tryptophan synthase activity
AAX08_06895	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AAX08_06925	COG0133	tryptophan synthase activity
AAX08_06930	COG4221	oxidoreductase activity
AAX08_06945	COG0442	prolyl-tRNA aminoacylation
AAX08_06950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AAX08_06955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AAX08_06960	COG1012	belongs to the aldehyde dehydrogenase family
AAX08_06965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AAX08_06970	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AAX08_06980	COG0783	Belongs to the Dps family
AAX08_07000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AAX08_07005	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AAX08_07060	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAX08_07065	COG2914	Belongs to the UPF0125 (RnfH) family
AAX08_07100	COG1610	YqeY-like protein
AAX08_07105	COG4783	chaperone-mediated protein folding
AAX08_07110	COG0425	Belongs to the sulfur carrier protein TusA family
AAX08_07120	COG2363	Small membrane protein
AAX08_07130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AAX08_07135	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AAX08_07140	COG4133	protoheme IX ABC transporter activity
AAX08_07180	COG0525	valine-tRNA ligase activity
AAX08_07190	COG0393	Putative heavy-metal-binding
AAX08_07220	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AAX08_07240	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AAX08_07245	COG0318	PFAM AMP-dependent synthetase and ligase
AAX08_07250	COG0318	PFAM AMP-dependent synthetase and ligase
AAX08_07260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AAX08_07270	COG0730	response to heat
AAX08_07275	COG1301	dicarboxylic acid transport
AAX08_07285	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AAX08_07340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AAX08_07350	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAX08_07360	COG0583	DNA-binding transcription factor activity
AAX08_07365	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AAX08_07380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AAX08_07390	COG2828	Protein conserved in bacteria
AAX08_07415	COG3023	N-Acetylmuramoyl-L-alanine amidase
AAX08_07435	COG2814	Major facilitator Superfamily
AAX08_07450	COG1115	amino acid carrier protein
AAX08_07455	COG2233	PERMEase
AAX08_07460	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AAX08_07490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AAX08_07495	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AAX08_07570	COG0582	viral genome integration into host DNA
AAX08_07580	COG1509	lysine 2,3-aminomutase activity
AAX08_07585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AAX08_07590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AAX08_07595	COG0084	hydrolase, TatD family'
AAX08_07650	COG1183	phosphatidylcholine synthase activity
AAX08_07655	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AAX08_07665	COG0697	spore germination
AAX08_07670	COG0697	spore germination
AAX08_07675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AAX08_07695	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AAX08_07700	COG2975	iron-sulfur cluster assembly
AAX08_07705	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AAX08_07710	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AAX08_07715	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AAX08_07730	COG0753	catalase activity
AAX08_07740	COG3022	response to hydroperoxide
AAX08_07745	COG0857	belongs to the CobB CobQ family
AAX08_07745	COG0280	phosphate acetyltransferase
AAX08_07750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AAX08_07755	COG0019	diaminopimelate decarboxylase activity
AAX08_07760	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AAX08_07785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AAX08_07810	COG0277	FAD linked oxidase domain protein
AAX08_07815	COG0459	protein refolding
AAX08_07820	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AAX08_07850	COG1295	ribonuclease BN
AAX08_07865	COG0540	Belongs to the ATCase OTCase family
AAX08_07870	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AAX08_07875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAX08_07880	COG1408	metallophosphoesterase
AAX08_07895	COG1278	Cold shock
AAX08_07905	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AAX08_07920	COG0440	acetolactate synthase activity
AAX08_07925	COG0028	Belongs to the TPP enzyme family
AAX08_07935	COG1652	LysM domain
AAX08_07955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AAX08_07965	COG3101	peptidyl-lysine hydroxylation
AAX08_07970	COG0009	L-threonylcarbamoyladenylate synthase
AAX08_07975	COG0203	ribosomal protein L17
AAX08_07980	COG0202	RNA polymerase activity
AAX08_07985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AAX08_07990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AAX08_08000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AAX08_08010	COG0200	Binds to the 23S rRNA
AAX08_08015	COG1841	ribosomal large subunit assembly
AAX08_08025	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AAX08_08030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AAX08_08035	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AAX08_08040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AAX08_08045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AAX08_08050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AAX08_08055	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AAX08_08060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AAX08_08065	COG0255	Belongs to the universal ribosomal protein uL29 family
AAX08_08070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AAX08_08075	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AAX08_08080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AAX08_08085	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AAX08_08090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AAX08_08095	COG0089	rRNA binding
AAX08_08100	COG0088	Forms part of the polypeptide exit tunnel
AAX08_08105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AAX08_08110	COG0051	transcription antitermination factor activity, RNA binding
AAX08_08115	COG1530	ribonuclease E activity
AAX08_08120	COG0424	maF-like protein
AAX08_08125	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAX08_08130	COG0154	amidase activity
AAX08_08135	COG1247	-acetyltransferase
AAX08_08140	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAX08_08155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AAX08_08160	COG1047	Peptidyl-prolyl cis-trans
AAX08_08165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AAX08_08190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AAX08_08195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AAX08_08220	COG1671	Belongs to the UPF0178 family
AAX08_08225	COG0628	permease
AAX08_08230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAX08_08255	COG2181	nitrate reductase activity
AAX08_08260	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AAX08_08265	COG1140	nitrate reductase beta subunit
AAX08_08270	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AAX08_08275	COG0629	single-stranded DNA binding
AAX08_08280	COG1064	alcohol dehydrogenase
AAX08_08290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AAX08_08310	COG0494	nUDIX hydrolase
AAX08_08320	COG0339	signal peptide processing
AAX08_08330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AAX08_08340	COG0049	tRNA binding
AAX08_08345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AAX08_08355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AAX08_08385	COG2814	Major facilitator Superfamily
AAX08_08395	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AAX08_08400	COG4535	Mg2 and Co2 transporter CorC
AAX08_08405	COG2983	Belongs to the UPF0260 family
AAX08_08415	COG2195	Cleaves the N-terminal amino acid of tripeptides
AAX08_08420	COG0561	phosphatase activity
AAX08_08430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAX08_08435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAX08_08440	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAX08_08445	COG0085	RNA polymerase activity
AAX08_08460	COG0081	regulation of translation
AAX08_08465	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AAX08_08485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AAX08_08535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAX08_08535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAX08_08545	COG2226	methyltransferase
AAX08_08550	COG0586	Pfam SNARE associated Golgi protein
AAX08_08560	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AAX08_08575	COG1674	ftsk spoiiie
AAX08_08580	COG0492	ferredoxin-NADP+ reductase activity
AAX08_08590	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AAX08_08595	COG2081	HI0933 family
AAX08_08600	COG4783	chaperone-mediated protein folding
AAX08_08605	COG0271	Belongs to the BolA IbaG family
AAX08_08615	COG0659	secondary active sulfate transmembrane transporter activity
AAX08_08625	COG0564	pseudouridine synthase activity
AAX08_08630	COG3118	belongs to the thioredoxin family
AAX08_08650	COG0653	protein targeting
AAX08_08655	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AAX08_08660	COG2824	Alkylphosphonate utilization operon protein PhnA
AAX08_08665	COG0675	Transposase, IS605 OrfB family
AAX08_08700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAX08_08700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAX08_08705	COG0354	folic acid binding
AAX08_08710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAX08_08720	COG0688	phosphatidylethanolamine metabolic process
AAX08_08730	COG1490	D-aminoacyl-tRNA deacylase activity
AAX08_08740	COG0751	glycine-tRNA ligase activity
AAX08_08750	COG0752	glycyl-tRNA synthetase alpha subunit
AAX08_08775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AAX08_08825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AAX08_08840	COG2831	hemolysin activation secretion protein
AAX08_08845	COG1192	Involved in chromosome partitioning
AAX08_08915	COG3210	domain, Protein
AAX08_08915	COG3210	domain, Protein
AAX08_08945	COG2732	(Barnase) inhibitor
AAX08_09030	COG2826	transposase and inactivated derivatives, IS30 family
AAX08_09040	COG3210	domain, Protein
AAX08_09065	COG2175	clavaminate synthase activity
AAX08_09075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AAX08_09080	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AAX08_09085	COG1056	cytidyltransferase-related domain
AAX08_09085	COG1051	belongs to the nudix hydrolase family
AAX08_09095	COG0786	glutamate:sodium symporter activity
AAX08_09105	COG5002	protein histidine kinase activity
AAX08_09105	COG2205	protein histidine kinase activity
AAX08_09105	COG0784	Response regulator, receiver
AAX08_09110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AAX08_09135	COG1185	polyribonucleotide nucleotidyltransferase activity
AAX08_09140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AAX08_09150	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AAX08_09155	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AAX08_09160	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AAX08_09175	COG0195	Participates in both transcription termination and antitermination
AAX08_09175	COG2251	uridine kinase activity
AAX08_09180	COG0779	Required for maturation of 30S ribosomal subunits
AAX08_09200	COG0149	triose-phosphate isomerase activity
AAX08_09215	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AAX08_09220	COG0237	dephospho-CoA kinase activity
AAX08_09245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AAX08_09260	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AAX08_09260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AAX08_09280	COG0488	(ABC) transporter
AAX08_09295	COG0183	Belongs to the thiolase family
AAX08_09310	COG2031	fatty acid transporter
AAX08_09315	COG1028	Short-chain dehydrogenase reductase Sdr
AAX08_09320	COG2610	gluconate transmembrane transporter activity
AAX08_09345	COG0641	radical SAM
AAX08_09350	COG0625	glutathione transferase activity
AAX08_09365	COG0583	DNA-binding transcription factor activity
AAX08_09370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAX08_09380	COG2154	pterin-4-alpha-carbinolamine dehydratase
AAX08_09400	COG0583	DNA-binding transcription factor activity
AAX08_09425	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AAX08_09430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAX08_09445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AAX08_09455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AAX08_09460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AAX08_09465	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AAX08_09470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AAX08_09485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAX08_09490	COG1960	acyl-CoA dehydrogenase activity
AAX08_09500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AAX08_09510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAX08_09515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAX08_09520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAX08_09550	COG1309	transcriptional regulator
AAX08_09560	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AAX08_09570	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAX08_09575	COG1116	anion transmembrane transporter activity
AAX08_09575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AAX08_09580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAX08_09585	COG1116	anion transmembrane transporter activity
AAX08_09585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AAX08_09595	COG3568	Endonuclease Exonuclease Phosphatase
AAX08_09605	COG0339	signal peptide processing
AAX08_09615	COG0259	pyridoxamine-phosphate oxidase activity
AAX08_09625	COG1946	Acyl-CoA thioesterase
AAX08_09635	COG0523	cobalamin synthesis protein
AAX08_09640	COG1619	proteins homologs of microcin C7 resistance protein MccF
AAX08_09645	COG1253	flavin adenine dinucleotide binding
AAX08_09650	COG1028	Short-chain dehydrogenase reductase Sdr
AAX08_09660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAX08_09670	COG3028	Belongs to the UPF0307 family
AAX08_09675	COG1660	Displays ATPase and GTPase activities
AAX08_09680	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AAX08_09685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AAX08_09690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AAX08_09695	COG0617	tRNA 3'-terminal CCA addition
AAX08_09700	COG1555	photosystem II stabilization
AAX08_09705	COG3956	TIGRFAM MazG family protein
AAX08_09720	COG0583	DNA-binding transcription factor activity
AAX08_09725	COG1960	acyl-CoA dehydrogenase activity
AAX08_09730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AAX08_09795	COG3150	esterase
AAX08_09830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AAX08_09835	COG2918	glutathione biosynthetic process
AAX08_09840	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AAX08_09845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AAX08_09855	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AAX08_09860	COG0165	Argininosuccinate lyase
AAX08_09870	COG0181	hydroxymethylbilane synthase activity
AAX08_09885	COG0443	Heat shock 70 kDa protein
AAX08_09890	COG0745	RESPONSE REGULATOR receiver
AAX08_09900	COG3135	benzoate transporter
AAX08_09935	COG2205	protein histidine kinase activity
AAX08_09945	COG2991	Protein conserved in bacteria
AAX08_09950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAX08_09955	COG0497	DNA recombination
AAX08_09960	COG1678	Uncharacterized ACR, COG1678
AAX08_09965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AAX08_09975	COG0425	Belongs to the sulfur carrier protein TusA family
AAX08_09980	COG4974	Belongs to the 'phage' integrase family
AAX08_09985	COG2813	Specifically methylates the guanine in position
AAX08_10000	COG0318	PFAM AMP-dependent synthetase and ligase
AAX08_10005	COG1309	transcriptional regulator
AAX08_10015	COG1960	acyl-CoA dehydrogenase activity
AAX08_10105	COG0758	DNA mediated transformation
AAX08_10115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AAX08_10115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAX08_10130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AAX08_10130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AAX08_10135	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AAX08_10140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AAX08_10145	COG0706	membrane insertase activity
AAX08_10150	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AAX08_10155	COG0594	ribonuclease P activity
AAX08_10160	COG0230	Belongs to the bacterial ribosomal protein bL34 family