MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 Gene3D G3DSA:3.30.1330.20 221 329 2.0E-30 T 14-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 Gene3D G3DSA:3.40.50.1440 3 220 4.3E-80 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 SUPERFAMILY SSF55307 204 317 3.43E-34 T 14-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 4.5E-40 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 354 34.776 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 PRINTS PR00423 Cell division protein FtsZ signature 99 119 6.0E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 PRINTS PR00423 Cell division protein FtsZ signature 127 148 6.0E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 PRINTS PR00423 Cell division protein FtsZ signature 189 211 6.0E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 PRINTS PR00423 Cell division protein FtsZ signature 212 233 6.0E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 ProSitePatterns PS01134 FtsZ protein signature 1. 45 79 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 Pfam PF12327 FtsZ family, C-terminal domain 222 315 3.9E-24 T 14-10-2018 IPR024757 Cell division protein FtsZ, C-terminal MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 SMART SM00864 14 205 1.7E-101 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 10 332 3.2E-121 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 SUPERFAMILY SSF52490 13 208 3.92E-67 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 ProSitePatterns PS01135 FtsZ protein signature 2. 98 119 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MCR_0308 7946c4ad62a2780fecbe7c4f0a5cd272 373 SMART SM00865 207 324 3.7E-35 T 14-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1060 0.0 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Gene3D G3DSA:3.40.50.20 556 664 1.4E-49 T 14-10-2018 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 SMART SM01096 426 549 1.4E-72 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 SUPERFAMILY SSF56059 675 934 1.36E-104 T 14-10-2018 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Gene3D G3DSA:3.40.50.20 1 116 5.1E-50 T 14-10-2018 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Pfam PF02142 MGS-like domain 963 1047 9.8E-19 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.5E-74 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 675 877 1.0E-35 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Gene3D G3DSA:1.10.1030.10 404 555 3.0E-49 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 SUPERFAMILY SSF52335 949 1077 5.1E-39 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 840 847 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 3.8E-41 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 SMART SM00851 963 1049 2.5E-31 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1070 13.169 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1075 13.505 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 SUPERFAMILY SSF56059 128 401 8.13E-111 T 14-10-2018 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Gene3D G3DSA:3.30.470.20 667 937 5.7E-119 T 14-10-2018 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 711 725 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 SUPERFAMILY SSF52440 559 677 5.9E-50 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 SUPERFAMILY SSF52440 1 127 8.06E-50 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Gene3D G3DSA:3.40.50.1380 947 1078 2.3E-35 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.5E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 1.5E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.5E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.5E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.5E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.5E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.5E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 Gene3D G3DSA:3.30.470.20 119 403 1.9E-132 T 14-10-2018 MCR_1119 fb020df00b237e04f461c555fc7f3512 1078 SUPERFAMILY SSF48108 396 556 6.67E-54 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 5.0E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 5.0E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 519 5.0E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 463 491 5.0E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 533 545 5.0E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 SUPERFAMILY SSF52954 528 633 1.81E-29 T 14-10-2018 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 Gene3D G3DSA:3.30.980.10 69 221 6.6E-60 T 14-10-2018 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 321 528 1.6E-45 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 Pfam PF02824 TGS domain 3 61 4.9E-14 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 SUPERFAMILY SSF81271 2 61 2.83E-17 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 SUPERFAMILY SSF55681 242 525 3.45E-102 T 14-10-2018 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 171 218 1.3E-14 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 Gene3D G3DSA:3.10.20.30 1 63 4.7E-25 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 Gene3D G3DSA:3.30.930.10 222 530 4.3E-130 T 14-10-2018 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 SUPERFAMILY SSF55186 64 240 2.22E-64 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 33.651 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 Gene3D G3DSA:3.40.50.800 531 637 1.2E-27 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 Pfam PF03129 Anticodon binding domain 540 628 5.2E-18 T 14-10-2018 IPR004154 Anticodon-binding MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 629 4.7E-224 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 Gene3D G3DSA:3.30.54.20 130 186 6.6E-60 T 14-10-2018 MCR_1451 f682b39abd4dfbb7bcda753a26c3c85b 639 SMART SM00863 169 218 2.1E-20 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MCR_1745 c0d89386f38e96e82dc68fe77b23e2ba 365 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 217 226 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MCR_1745 c0d89386f38e96e82dc68fe77b23e2ba 365 Gene3D G3DSA:3.90.1150.10 24 351 3.1E-108 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_1745 c0d89386f38e96e82dc68fe77b23e2ba 365 Pfam PF00155 Aminotransferase class I and II 28 356 2.4E-62 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MCR_1745 c0d89386f38e96e82dc68fe77b23e2ba 365 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 360 8.8E-94 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MCR_1745 c0d89386f38e96e82dc68fe77b23e2ba 365 Gene3D G3DSA:3.40.640.10 41 269 3.1E-108 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_1745 c0d89386f38e96e82dc68fe77b23e2ba 365 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 361 55.806 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MCR_1745 c0d89386f38e96e82dc68fe77b23e2ba 365 SUPERFAMILY SSF53383 24 359 3.89E-76 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 Gene3D G3DSA:3.30.230.10 611 798 1.3E-76 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 Gene3D G3DSA:1.10.8.60 509 610 4.3E-30 T 14-10-2018 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 Gene3D G3DSA:1.20.58.1480 115 261 4.8E-22 T 14-10-2018 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 596 798 3.4E-91 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 729 748 1.2E-53 T 14-10-2018 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 621 637 1.2E-53 T 14-10-2018 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 699 718 1.2E-53 T 14-10-2018 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 752 770 1.2E-53 T 14-10-2018 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 374 393 1.2E-53 T 14-10-2018 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 TIGRFAM TIGR00763 lon: endopeptidase La 21 796 2.5E-281 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 SUPERFAMILY SSF52540 331 612 7.22E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 702 710 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 SUPERFAMILY SSF54211 621 796 6.83E-56 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 SMART SM00464 19 219 2.6E-31 T 14-10-2018 IPR003111 Lon, substrate-binding domain MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 370 506 3.0E-20 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 20 208 7.6E-23 T 14-10-2018 IPR003111 Lon, substrate-binding domain MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 SMART SM00382 366 510 7.2E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 Gene3D G3DSA:3.40.50.300 331 508 2.2E-64 T 14-10-2018 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 Hamap MF_01973 Lon protease [lon]. 20 798 63.908 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 SUPERFAMILY SSF88697 19 216 1.27E-19 T 14-10-2018 IPR015947 PUA-like superfamily MCR_0801 d2a5f44a820593c1c7cf32df20bf2716 820 PIRSF PIRSF001174 7 800 4.9E-303 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MCR_1723 c73b5ff9de5d5442342be01ed6be39ed 281 SUPERFAMILY SSF161098 28 269 5.89E-35 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1723 c73b5ff9de5d5442342be01ed6be39ed 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 268 3.8E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_1723 c73b5ff9de5d5442342be01ed6be39ed 281 Gene3D G3DSA:1.10.3720.10 14 270 1.7E-32 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0887 f6879e5762b6f74b7a60375d25905450 370 Pfam PF00800 Prephenate dehydratase 102 279 7.7E-62 T 14-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 Pfam PF01842 ACT domain 288 352 6.5E-9 T 14-10-2018 IPR002912 ACT domain MCR_0887 f6879e5762b6f74b7a60375d25905450 370 SUPERFAMILY SSF48600 13 102 2.44E-19 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 253 275 - T 14-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 Gene3D G3DSA:3.40.190.10 105 275 1.1E-58 T 14-10-2018 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 SUPERFAMILY SSF55021 272 367 2.85E-26 T 14-10-2018 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 TIGRFAM TIGR01807 CM_P2: chorismate mutase 16 90 5.1E-28 T 14-10-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 SMART SM00830 19 100 8.0E-29 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 Gene3D G3DSA:1.20.59.10 18 104 1.1E-29 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 Pfam PF01817 Chorismate mutase type II 19 98 5.0E-23 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 Gene3D G3DSA:3.30.70.260 280 369 4.5E-27 T 14-10-2018 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 PIRSF PIRSF001500 10 370 2.0E-134 T 14-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 SUPERFAMILY SSF53850 101 285 5.97E-59 T 14-10-2018 MCR_0887 f6879e5762b6f74b7a60375d25905450 370 Gene3D G3DSA:3.40.190.10 182 267 1.1E-58 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 521 1.1E-207 T 14-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SUPERFAMILY SSF50249 2 113 6.34E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Gene3D G3DSA:2.40.50.140 359 444 5.9E-25 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Gene3D G3DSA:2.40.50.140 270 358 2.8E-28 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SUPERFAMILY SSF50249 190 277 1.12E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SUPERFAMILY SSF50249 451 534 7.46E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SUPERFAMILY SSF50249 256 357 2.46E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Pfam PF00575 S1 RNA binding domain 362 435 3.4E-19 T 14-10-2018 IPR003029 S1 domain GO:0003676 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Pfam PF00575 S1 RNA binding domain 189 261 6.5E-21 T 14-10-2018 IPR003029 S1 domain GO:0003676 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Pfam PF00575 S1 RNA binding domain 452 521 3.5E-15 T 14-10-2018 IPR003029 S1 domain GO:0003676 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Pfam PF00575 S1 RNA binding domain 20 87 2.8E-5 T 14-10-2018 IPR003029 S1 domain GO:0003676 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Pfam PF00575 S1 RNA binding domain 103 172 2.3E-14 T 14-10-2018 IPR003029 S1 domain GO:0003676 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Pfam PF00575 S1 RNA binding domain 276 348 1.1E-18 T 14-10-2018 IPR003029 S1 domain GO:0003676 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 PRINTS PR00681 Ribosomal protein S1 signature 22 40 1.4E-87 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 PRINTS PR00681 Ribosomal protein S1 signature 40 54 1.4E-87 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 PRINTS PR00681 Ribosomal protein S1 signature 291 310 1.4E-87 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 PRINTS PR00681 Ribosomal protein S1 signature 331 349 1.4E-87 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 PRINTS PR00681 Ribosomal protein S1 signature 127 144 1.4E-87 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 PRINTS PR00681 Ribosomal protein S1 signature 213 234 1.4E-87 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 PRINTS PR00681 Ribosomal protein S1 signature 109 125 1.4E-87 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 PRINTS PR00681 Ribosomal protein S1 signature 156 176 1.4E-87 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 PRINTS PR00681 Ribosomal protein S1 signature 85 104 1.4E-87 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Gene3D G3DSA:2.40.50.140 188 269 7.5E-27 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SMART SM00316 191 261 1.9E-27 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SMART SM00316 20 88 5.7E-6 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SMART SM00316 276 348 2.4E-23 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SMART SM00316 104 172 2.1E-10 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SMART SM00316 450 521 2.9E-19 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SMART SM00316 363 435 2.7E-21 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Gene3D G3DSA:2.40.50.140 6 100 4.6E-17 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Gene3D G3DSA:2.40.50.140 101 186 9.7E-9 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 PIRSF PIRSF002111 1 535 1.4E-209 T 14-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 Gene3D G3DSA:2.40.50.140 445 529 9.8E-21 T 14-10-2018 MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SUPERFAMILY SSF50249 343 441 2.61E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0868 f9a502935b458cc96886bd1c975b8e63 557 SUPERFAMILY SSF50249 104 185 2.31E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.2E-38 T 14-10-2018 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.2E-38 T 14-10-2018 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.2E-38 T 14-10-2018 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.2E-38 T 14-10-2018 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 1.2E-38 T 14-10-2018 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 311 5.1E-121 T 14-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 134 154 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 Gene3D G3DSA:3.50.50.60 7 310 1.3E-123 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 Gene3D G3DSA:3.50.50.60 116 242 1.3E-123 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 7.4E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 7.4E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 274 292 7.4E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 7.4E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 236 257 7.4E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 7.4E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 7.4E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 7.4E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 7.4E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 298 5.9E-51 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MCR_0230 ade37f38e17763920b23ed68ca77c9fb 316 SUPERFAMILY SSF51905 1 311 4.35E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1146 8bc3fb6947c707eea714db8cd36ab881 253 SUPERFAMILY SSF69572 9 252 2.62E-73 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MCR_1146 8bc3fb6947c707eea714db8cd36ab881 253 Pfam PF00899 ThiF family 18 248 5.2E-58 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MCR_1146 8bc3fb6947c707eea714db8cd36ab881 253 Gene3D G3DSA:3.40.50.720 10 253 3.1E-76 T 14-10-2018 MCR_1313 18bbd7d1114138dc41be082badf53fbc 342 Pfam PF01343 Peptidase family S49 155 299 1.7E-44 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MCR_1313 18bbd7d1114138dc41be082badf53fbc 342 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 89 297 2.9E-57 T 14-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 MCR_1313 18bbd7d1114138dc41be082badf53fbc 342 SUPERFAMILY SSF52096 85 289 2.78E-39 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MCR_1313 18bbd7d1114138dc41be082badf53fbc 342 Gene3D G3DSA:3.90.226.10 91 293 2.3E-68 T 14-10-2018 MCR_1313 18bbd7d1114138dc41be082badf53fbc 342 Gene3D G3DSA:3.40.1750.20 192 260 2.3E-68 T 14-10-2018 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 Pfam PF00344 SecY translocase 54 391 4.5E-108 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 PIRSF PIRSF004557 1 411 9.4E-112 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 Gene3D G3DSA:1.10.3370.10 1 404 7.1E-147 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 Hamap MF_01465 Protein translocase subunit SecY [secY]. 1 408 27.172 T 14-10-2018 IPR026593 Protein translocase subunit SecY MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 SUPERFAMILY SSF103491 1 399 5.89E-117 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 PRINTS PR00303 Preprotein translocase SecY subunit signature 128 153 6.3E-88 T 14-10-2018 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 PRINTS PR00303 Preprotein translocase SecY subunit signature 94 117 6.3E-88 T 14-10-2018 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 PRINTS PR00303 Preprotein translocase SecY subunit signature 290 312 6.3E-88 T 14-10-2018 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 PRINTS PR00303 Preprotein translocase SecY subunit signature 1 19 6.3E-88 T 14-10-2018 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 PRINTS PR00303 Preprotein translocase SecY subunit signature 53 73 6.3E-88 T 14-10-2018 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 PRINTS PR00303 Preprotein translocase SecY subunit signature 345 363 6.3E-88 T 14-10-2018 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 PRINTS PR00303 Preprotein translocase SecY subunit signature 377 395 6.3E-88 T 14-10-2018 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 PRINTS PR00303 Preprotein translocase SecY subunit signature 154 177 6.3E-88 T 14-10-2018 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 PRINTS PR00303 Preprotein translocase SecY subunit signature 243 262 6.3E-88 T 14-10-2018 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 2 404 4.2E-116 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MCR_1565 adc0e2cbaa828cbea2257770f4c64500 413 ProSitePatterns PS00755 Protein secY signature 1. 54 73 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 Gene3D G3DSA:3.40.50.720 317 500 2.8E-68 T 14-10-2018 MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 109 129 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 Gene3D G3DSA:1.10.1040.50 501 712 1.4E-77 T 14-10-2018 MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 Gene3D G3DSA:3.90.226.10 1 316 3.9E-95 T 14-10-2018 MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 SUPERFAMILY SSF48179 627 717 4.68E-24 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 497 521 - T 14-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 320 498 3.4E-61 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 208 1.4E-42 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 SUPERFAMILY SSF48179 499 643 1.19E-30 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 SUPERFAMILY SSF52096 14 310 2.06E-68 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 SUPERFAMILY SSF51735 316 499 8.74E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 500 595 5.1E-24 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MCR_0091 1ecc4d1e83ade11eafc377c08720c31d 717 TIGRFAM TIGR02437 FadB: fatty oxidation complex, alpha subunit FadB 1 717 0.0 T 14-10-2018 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-7292|MetaCyc: PWY-7307|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MCR_0055 d69624b968c0b96ef6dd2327db98c417 197 Gene3D G3DSA:3.30.230.30 1 131 6.9E-48 T 14-10-2018 IPR036956 Impact, N-terminal domain superfamily MCR_0055 d69624b968c0b96ef6dd2327db98c417 197 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 5 188 3.7E-50 T 14-10-2018 IPR015796 Impact family, bacterial/archaeal MCR_0055 d69624b968c0b96ef6dd2327db98c417 197 SUPERFAMILY SSF54211 3 127 2.62E-40 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_0055 d69624b968c0b96ef6dd2327db98c417 197 Pfam PF01205 Uncharacterized protein family UPF0029 17 123 3.6E-31 T 14-10-2018 IPR001498 Impact, N-terminal MCR_0055 d69624b968c0b96ef6dd2327db98c417 197 Pfam PF09186 Domain of unknown function (DUF1949) 140 187 3.0E-8 T 14-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal MCR_0055 d69624b968c0b96ef6dd2327db98c417 197 SUPERFAMILY SSF54980 135 188 6.33E-8 T 14-10-2018 IPR035647 EF-G domain III/V-like MCR_0055 d69624b968c0b96ef6dd2327db98c417 197 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 14-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site MCR_1490 efd9a3479f423811bfe75dd1a46b737e 170 Pfam PF00186 Dihydrofolate reductase 6 167 4.6E-53 T 14-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MCR_1490 efd9a3479f423811bfe75dd1a46b737e 170 PRINTS PR00070 Dihydrofolate reductase signature 31 39 5.3E-16 T 14-10-2018 MCR_1490 efd9a3479f423811bfe75dd1a46b737e 170 PRINTS PR00070 Dihydrofolate reductase signature 100 114 5.3E-16 T 14-10-2018 MCR_1490 efd9a3479f423811bfe75dd1a46b737e 170 PRINTS PR00070 Dihydrofolate reductase signature 17 27 5.3E-16 T 14-10-2018 MCR_1490 efd9a3479f423811bfe75dd1a46b737e 170 PRINTS PR00070 Dihydrofolate reductase signature 44 55 5.3E-16 T 14-10-2018 MCR_1490 efd9a3479f423811bfe75dd1a46b737e 170 PIRSF PIRSF000194 1 169 1.8E-53 T 14-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 MCR_1490 efd9a3479f423811bfe75dd1a46b737e 170 SUPERFAMILY SSF53597 6 167 1.13E-52 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MCR_1490 efd9a3479f423811bfe75dd1a46b737e 170 Gene3D G3DSA:3.40.430.10 4 169 1.4E-51 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MCR_1602 09307bc6564cba9a0954ae2f563be4d2 498 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 37 435 2.5E-97 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MCR_1602 09307bc6564cba9a0954ae2f563be4d2 498 Pfam PF00474 Sodium:solute symporter family 37 435 1.5E-104 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MCR_1602 09307bc6564cba9a0954ae2f563be4d2 498 Gene3D G3DSA:1.20.1730.10 24 494 5.9E-95 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily MCR_1602 09307bc6564cba9a0954ae2f563be4d2 498 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 8 496 7.2E-205 T 14-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 MCR_1602 09307bc6564cba9a0954ae2f563be4d2 498 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 417 437 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site MCR_0850 38a35597b669e042e4dc075a2c0be428 353 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 5 345 3.2E-84 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MCR_0850 38a35597b669e042e4dc075a2c0be428 353 SUPERFAMILY SSF52374 6 345 9.92E-84 T 14-10-2018 MCR_0850 38a35597b669e042e4dc075a2c0be428 353 Gene3D G3DSA:1.10.240.10 204 313 5.8E-113 T 14-10-2018 MCR_0850 38a35597b669e042e4dc075a2c0be428 353 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 18 34 2.8E-20 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MCR_0850 38a35597b669e042e4dc075a2c0be428 353 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 74 93 2.8E-20 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MCR_0850 38a35597b669e042e4dc075a2c0be428 353 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 158 179 2.8E-20 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MCR_0850 38a35597b669e042e4dc075a2c0be428 353 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 209 219 2.8E-20 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MCR_0850 38a35597b669e042e4dc075a2c0be428 353 Gene3D G3DSA:3.40.50.620 7 345 5.8E-113 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0850 38a35597b669e042e4dc075a2c0be428 353 Pfam PF00579 tRNA synthetases class I (W and Y) 3 297 6.6E-53 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0850 38a35597b669e042e4dc075a2c0be428 353 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 5 346 34.984 T 14-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 MCR_0045 55146d83aacceb82c5a7449b94e96e9c 279 Pfam PF00226 DnaJ domain 8 68 2.0E-16 T 14-10-2018 IPR001623 DnaJ domain MCR_0045 55146d83aacceb82c5a7449b94e96e9c 279 SUPERFAMILY SSF46565 7 83 7.72E-20 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MCR_0045 55146d83aacceb82c5a7449b94e96e9c 279 Gene3D G3DSA:2.60.260.20 209 279 3.5E-6 T 14-10-2018 MCR_0045 55146d83aacceb82c5a7449b94e96e9c 279 SMART SM00271 7 63 4.7E-13 T 14-10-2018 IPR001623 DnaJ domain MCR_0045 55146d83aacceb82c5a7449b94e96e9c 279 SUPERFAMILY SSF49493 212 278 4.58E-5 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MCR_0045 55146d83aacceb82c5a7449b94e96e9c 279 PRINTS PR00625 DnaJ domain signature 10 28 1.5E-6 T 14-10-2018 IPR001623 DnaJ domain MCR_0045 55146d83aacceb82c5a7449b94e96e9c 279 PRINTS PR00625 DnaJ domain signature 28 43 1.5E-6 T 14-10-2018 IPR001623 DnaJ domain MCR_0045 55146d83aacceb82c5a7449b94e96e9c 279 PRINTS PR00625 DnaJ domain signature 82 102 1.5E-6 T 14-10-2018 IPR001623 DnaJ domain MCR_0045 55146d83aacceb82c5a7449b94e96e9c 279 Gene3D G3DSA:1.10.287.110 3 93 1.2E-19 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MCR_0285 6d0b8e858e82bc281dfcf32f0e48f988 212 Gene3D G3DSA:3.30.2010.10 122 210 2.9E-19 T 14-10-2018 MCR_0285 6d0b8e858e82bc281dfcf32f0e48f988 212 Pfam PF01863 Protein of unknown function DUF45 23 212 1.2E-36 T 14-10-2018 IPR002725 Protein of unknown function DUF45 MCR_1099 fee34d43b07ee994a1b2cbf71029e966 91 Pfam PF00313 'Cold-shock' DNA-binding domain 28 90 2.2E-28 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MCR_1099 fee34d43b07ee994a1b2cbf71029e966 91 ProSitePatterns PS00352 'Cold-shock' domain signature. 40 58 - T 14-10-2018 IPR019844 Cold-shock conserved site MCR_1099 fee34d43b07ee994a1b2cbf71029e966 91 SUPERFAMILY SSF50249 22 90 9.64E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1099 fee34d43b07ee994a1b2cbf71029e966 91 Gene3D G3DSA:2.40.50.140 26 91 4.1E-28 T 14-10-2018 MCR_1099 fee34d43b07ee994a1b2cbf71029e966 91 PIRSF PIRSF002599 22 91 1.3E-22 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 MCR_1099 fee34d43b07ee994a1b2cbf71029e966 91 SMART SM00357 28 91 2.7E-28 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 MCR_1099 fee34d43b07ee994a1b2cbf71029e966 91 PRINTS PR00050 Cold shock protein signature 49 58 8.9E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MCR_1099 fee34d43b07ee994a1b2cbf71029e966 91 PRINTS PR00050 Cold shock protein signature 64 82 8.9E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MCR_1099 fee34d43b07ee994a1b2cbf71029e966 91 PRINTS PR00050 Cold shock protein signature 29 44 8.9E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MCR_1170 0474e813138aea45a6ee743c4c91a034 422 Gene3D G3DSA:3.40.50.800 333 420 1.3E-20 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily MCR_1170 0474e813138aea45a6ee743c4c91a034 422 Pfam PF03129 Anticodon binding domain 357 417 3.8E-8 T 14-10-2018 IPR004154 Anticodon-binding MCR_1170 0474e813138aea45a6ee743c4c91a034 422 SUPERFAMILY SSF52954 336 417 2.11E-13 T 14-10-2018 MCR_1170 0474e813138aea45a6ee743c4c91a034 422 Gene3D G3DSA:3.30.930.10 1 329 1.1E-108 T 14-10-2018 MCR_1170 0474e813138aea45a6ee743c4c91a034 422 Pfam PF13393 Histidyl-tRNA synthetase 9 319 2.9E-44 T 14-10-2018 MCR_1170 0474e813138aea45a6ee743c4c91a034 422 PIRSF PIRSF001549 1 419 3.1E-113 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MCR_1170 0474e813138aea45a6ee743c4c91a034 422 SUPERFAMILY SSF55681 5 323 2.11E-93 T 14-10-2018 MCR_1170 0474e813138aea45a6ee743c4c91a034 422 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 415 1.9E-143 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MCR_1170 0474e813138aea45a6ee743c4c91a034 422 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 422 31.234 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MCR_0696 8bd2af5c7c2adb9f1a0cbeaa5b6503f8 267 PIRSF PIRSF005902 1 261 1.2E-67 T 14-10-2018 IPR001130 TatD family GO:0016788 MCR_0696 8bd2af5c7c2adb9f1a0cbeaa5b6503f8 267 Gene3D G3DSA:3.20.20.140 1 263 9.9E-77 T 14-10-2018 MCR_0696 8bd2af5c7c2adb9f1a0cbeaa5b6503f8 267 SUPERFAMILY SSF51556 1 259 1.54E-69 T 14-10-2018 IPR032466 Metal-dependent hydrolase MCR_0696 8bd2af5c7c2adb9f1a0cbeaa5b6503f8 267 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 3 256 1.9E-72 T 14-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 MCR_0696 8bd2af5c7c2adb9f1a0cbeaa5b6503f8 267 Pfam PF01026 TatD related DNase 3 256 3.0E-62 T 14-10-2018 IPR001130 TatD family GO:0016788 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 Gene3D G3DSA:3.40.50.720 182 463 3.8E-81 T 14-10-2018 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 Pfam PF01515 Phosphate acetyl/butaryl transferase 449 767 1.3E-90 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 Gene3D G3DSA:3.40.50.10380 16 181 1.3E-69 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 ProSitePatterns PS00331 Malic enzymes signature. 180 196 - T 14-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 SUPERFAMILY SSF53659 448 773 3.58E-84 T 14-10-2018 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 Gene3D G3DSA:3.40.50.10950 464 767 2.3E-88 T 14-10-2018 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 SMART SM00919 184 419 1.1E-128 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 SUPERFAMILY SSF51735 184 470 6.4E-88 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 PIRSF PIRSF036684 19 775 0.0 T 14-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 Pfam PF03949 Malic enzyme, NAD binding domain 186 377 4.3E-24 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 Gene3D G3DSA:3.40.50.10750 591 744 2.3E-88 T 14-10-2018 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 Pfam PF00390 Malic enzyme, N-terminal domain 40 172 6.3E-28 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 SUPERFAMILY SSF53223 31 182 1.94E-53 T 14-10-2018 MCR_0455 2ce6e5321a2096ff919f254191a36c02 776 SMART SM01274 39 172 1.6E-79 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MCR_0314 0e546dd15399b9805f3fa534bd49715f 472 Pfam PF01565 FAD binding domain 44 180 1.2E-37 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MCR_0314 0e546dd15399b9805f3fa534bd49715f 472 Gene3D G3DSA:3.30.465.40 6 232 2.5E-68 T 14-10-2018 MCR_0314 0e546dd15399b9805f3fa534bd49715f 472 SUPERFAMILY SSF55103 223 459 1.62E-69 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MCR_0314 0e546dd15399b9805f3fa534bd49715f 472 Gene3D G3DSA:3.30.70.2740 336 417 6.1E-12 T 14-10-2018 MCR_0314 0e546dd15399b9805f3fa534bd49715f 472 Gene3D G3DSA:1.10.45.10 418 456 7.0E-12 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MCR_0314 0e546dd15399b9805f3fa534bd49715f 472 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 456 8.3E-65 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MCR_0314 0e546dd15399b9805f3fa534bd49715f 472 SUPERFAMILY SSF56176 3 217 1.92E-64 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MCR_0704 d65be745b03bb7bc50548ba49ef3af82 70 Pfam PF00403 Heavy-metal-associated domain 6 66 1.8E-17 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MCR_0704 d65be745b03bb7bc50548ba49ef3af82 70 PRINTS PR00942 Copper-transporting ATPase 1 signature 3 28 1.1E-8 T 14-10-2018 MCR_0704 d65be745b03bb7bc50548ba49ef3af82 70 PRINTS PR00942 Copper-transporting ATPase 1 signature 29 52 1.1E-8 T 14-10-2018 MCR_0704 d65be745b03bb7bc50548ba49ef3af82 70 PRINTS PR00942 Copper-transporting ATPase 1 signature 58 70 1.1E-8 T 14-10-2018 MCR_0704 d65be745b03bb7bc50548ba49ef3af82 70 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MCR_0704 d65be745b03bb7bc50548ba49ef3af82 70 Gene3D G3DSA:3.30.70.100 1 70 2.8E-23 T 14-10-2018 MCR_0704 d65be745b03bb7bc50548ba49ef3af82 70 SUPERFAMILY SSF55008 1 68 9.29E-21 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MCR_1834 c080aa058174fe3da4abe986e19bec3d 280 SUPERFAMILY SSF51621 17 280 4.24E-96 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MCR_1834 c080aa058174fe3da4abe986e19bec3d 280 Gene3D G3DSA:3.20.20.60 4 280 7.9E-101 T 14-10-2018 MCR_1834 c080aa058174fe3da4abe986e19bec3d 280 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 16 280 2.7E-98 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MCR_1834 c080aa058174fe3da4abe986e19bec3d 280 PIRSF PIRSF000388 8 280 4.5E-94 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MCR_1834 c080aa058174fe3da4abe986e19bec3d 280 Pfam PF02548 Ketopantoate hydroxymethyltransferase 17 275 1.2E-101 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MCR_1834 c080aa058174fe3da4abe986e19bec3d 280 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 17 280 39.102 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MCR_0008 b813ff60e5d5977758e28e505588c6ea 405 Pfam PF13449 Esterase-like activity of phytase 64 379 2.4E-56 T 14-10-2018 IPR027372 Phytase-like domain MCR_1574 31e1c12ea4b925be8071950aa714442d 96 SUPERFAMILY SSF50104 1 92 1.0E-26 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily MCR_1574 31e1c12ea4b925be8071950aa714442d 96 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 28 92 2.1E-23 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1574 31e1c12ea4b925be8071950aa714442d 96 Gene3D G3DSA:2.30.30.30 1 94 6.0E-30 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 MCR_1574 31e1c12ea4b925be8071950aa714442d 96 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 93 1.6E-29 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1574 31e1c12ea4b925be8071950aa714442d 96 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 87 12.977 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0159 c137057ee1a78386343f0b02c4d40c98 146 PIRSF PIRSF016789 28 146 1.7E-32 T 14-10-2018 IPR007401 Protein of unknown function DUF454 MCR_0159 c137057ee1a78386343f0b02c4d40c98 146 Pfam PF04304 Protein of unknown function (DUF454) 29 144 9.8E-35 T 14-10-2018 IPR007401 Protein of unknown function DUF454 MCR_1878 f5856dfa2b06cb4712dbf0431370ebd2 266 SUPERFAMILY SSF161111 83 263 3.53E-30 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MCR_1878 f5856dfa2b06cb4712dbf0431370ebd2 266 Pfam PF01545 Cation efflux family 93 263 1.8E-15 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MCR_1878 f5856dfa2b06cb4712dbf0431370ebd2 266 SUPERFAMILY SSF55008 1 67 1.44E-9 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MCR_1878 f5856dfa2b06cb4712dbf0431370ebd2 266 Gene3D G3DSA:1.20.1510.10 86 265 1.6E-10 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 296 308 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 SMART SM01240 7 476 0.0 T 14-10-2018 MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 476 1.8E-158 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 Gene3D G3DSA:3.20.20.70 2 489 1.2E-205 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 SMART SM00116 159 207 4.3E-5 T 14-10-2018 IPR000644 CBS domain MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 SMART SM00116 96 145 3.2E-11 T 14-10-2018 IPR000644 CBS domain MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 457 2.8E-184 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 SUPERFAMILY SSF51412 2 480 9.29E-124 T 14-10-2018 MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 SUPERFAMILY SSF54631 95 204 6.39E-27 T 14-10-2018 MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 489 81.187 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 Pfam PF00571 CBS domain 150 202 2.6E-4 T 14-10-2018 IPR000644 CBS domain MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 Pfam PF00571 CBS domain 96 141 4.7E-10 T 14-10-2018 IPR000644 CBS domain MCR_0491 89ab4ec0635d762720ebcad8cef9f449 490 PIRSF PIRSF000130 2 490 2.6E-200 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MCR_0842 79c84fb286b714e5fe0ae6ac7bcadb62 211 Pfam PF03641 Possible lysine decarboxylase 52 182 5.8E-38 T 14-10-2018 IPR031100 LOG family MCR_0842 79c84fb286b714e5fe0ae6ac7bcadb62 211 SUPERFAMILY SSF102405 7 185 1.68E-58 T 14-10-2018 MCR_0842 79c84fb286b714e5fe0ae6ac7bcadb62 211 Gene3D G3DSA:3.40.50.450 2 201 7.4E-71 T 14-10-2018 MCR_0842 79c84fb286b714e5fe0ae6ac7bcadb62 211 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 10 185 1.1E-58 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG MCR_1477 bdcadc6bc2d2b68f9b8496d93fe25ae7 257 Pfam PF03883 Peroxide stress protein YaaA 1 243 4.4E-85 T 14-10-2018 IPR005583 Peroxide stress protein YaaA MCR_1477 bdcadc6bc2d2b68f9b8496d93fe25ae7 257 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 256 33.35 T 14-10-2018 IPR005583 Peroxide stress protein YaaA MCR_1894 987ff785f0a51073c46ce63aeb9ee395 471 Gene3D G3DSA:3.40.50.1100 109 448 1.1E-137 T 14-10-2018 MCR_1894 987ff785f0a51073c46ce63aeb9ee395 471 SUPERFAMILY SSF53686 1 467 5.14E-158 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MCR_1894 987ff785f0a51073c46ce63aeb9ee395 471 Pfam PF14821 Threonine synthase N terminus 2 79 4.4E-32 T 14-10-2018 IPR029144 Threonine synthase, N-terminal MCR_1894 987ff785f0a51073c46ce63aeb9ee395 471 Gene3D G3DSA:3.40.50.1100 98 436 1.1E-137 T 14-10-2018 MCR_1894 987ff785f0a51073c46ce63aeb9ee395 471 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 102 309 5.6E-14 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MCR_1894 987ff785f0a51073c46ce63aeb9ee395 471 Gene3D G3DSA:3.90.1380.10 1 91 2.0E-32 T 14-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily MCR_1894 987ff785f0a51073c46ce63aeb9ee395 471 TIGRFAM TIGR00260 thrC: threonine synthase 80 438 1.2E-77 T 14-10-2018 IPR004450 Threonine synthase-like MCR_1178 59008ecacd537552017a664d7707b010 1240 SUPERFAMILY SSF89550 16 76 3.53E-6 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MCR_1178 59008ecacd537552017a664d7707b010 1240 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 314 762 3.5E-166 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1178 59008ecacd537552017a664d7707b010 1240 SUPERFAMILY SSF160975 861 898 7.59E-5 T 14-10-2018 MCR_1178 59008ecacd537552017a664d7707b010 1240 Pfam PF14579 Helix-hairpin-helix motif 836 919 3.8E-26 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1178 59008ecacd537552017a664d7707b010 1240 Gene3D G3DSA:1.10.150.870 832 911 3.5E-6 T 14-10-2018 MCR_1178 59008ecacd537552017a664d7707b010 1240 SMART SM00481 4 71 1.9E-17 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MCR_1178 59008ecacd537552017a664d7707b010 1240 Pfam PF02811 PHP domain 5 176 5.3E-27 T 14-10-2018 IPR004013 PHP domain GO:0003824 MCR_1178 59008ecacd537552017a664d7707b010 1240 Gene3D G3DSA:3.20.20.140 1 288 4.1E-69 T 14-10-2018 MCR_1178 59008ecacd537552017a664d7707b010 1240 Gene3D G3DSA:1.10.10.1600 455 537 4.3E-25 T 14-10-2018 MCR_1178 59008ecacd537552017a664d7707b010 1240 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 1043 0.0 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1776 87b98be0eeb480bc3c67af2bf1abf8e5 652 SUPERFAMILY SSF56519 97 310 1.7E-26 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MCR_1776 87b98be0eeb480bc3c67af2bf1abf8e5 652 Gene3D G3DSA:3.30.450.330 312 637 6.2E-106 T 14-10-2018 MCR_1776 87b98be0eeb480bc3c67af2bf1abf8e5 652 Gene3D G3DSA:3.40.710.10 372 554 6.2E-106 T 14-10-2018 MCR_1776 87b98be0eeb480bc3c67af2bf1abf8e5 652 Pfam PF00905 Penicillin binding protein transpeptidase domain 339 633 7.6E-72 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MCR_1776 87b98be0eeb480bc3c67af2bf1abf8e5 652 Pfam PF03717 Penicillin-binding Protein dimerisation domain 97 294 1.1E-17 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MCR_1776 87b98be0eeb480bc3c67af2bf1abf8e5 652 SUPERFAMILY SSF56601 262 646 2.19E-88 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MCR_1776 87b98be0eeb480bc3c67af2bf1abf8e5 652 Gene3D G3DSA:3.90.1310.30 94 310 1.5E-28 T 14-10-2018 MCR_1265 1e02090efface957db1e410588302c32 137 Pfam PF00581 Rhodanese-like domain 40 126 3.4E-13 T 14-10-2018 IPR001763 Rhodanese-like domain MCR_1265 1e02090efface957db1e410588302c32 137 SMART SM00450 37 130 1.1E-12 T 14-10-2018 IPR001763 Rhodanese-like domain MCR_1265 1e02090efface957db1e410588302c32 137 SUPERFAMILY SSF52821 14 132 7.6E-24 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MCR_1265 1e02090efface957db1e410588302c32 137 Gene3D G3DSA:3.40.250.10 36 135 2.4E-17 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 Hamap MF_01201 Alanine racemase. 1 370 30.242 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 Pfam PF01168 Alanine racemase, N-terminal domain 8 229 1.3E-51 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 SUPERFAMILY SSF50621 238 371 2.86E-39 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 Gene3D G3DSA:3.20.20.10 10 227 2.3E-106 T 14-10-2018 IPR029066 PLP-binding barrel MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 Pfam PF00842 Alanine racemase, C-terminal domain 243 368 2.1E-36 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 SUPERFAMILY SSF51419 8 244 5.37E-54 T 14-10-2018 IPR029066 PLP-binding barrel MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 TIGRFAM TIGR00492 alr: alanine racemase 3 370 4.8E-86 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 SMART SM01005 243 370 5.7E-51 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 Gene3D G3DSA:2.40.37.10 8 364 2.3E-106 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 PRINTS PR00992 Alanine racemase signature 128 140 1.8E-40 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 PRINTS PR00992 Alanine racemase signature 202 229 1.8E-40 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 PRINTS PR00992 Alanine racemase signature 259 274 1.8E-40 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 PRINTS PR00992 Alanine racemase signature 160 171 1.8E-40 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 PRINTS PR00992 Alanine racemase signature 27 43 1.8E-40 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 PRINTS PR00992 Alanine racemase signature 352 365 1.8E-40 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1036 f3d246c6dfa62b9c2fe2a524b7f52707 380 PRINTS PR00992 Alanine racemase signature 276 291 1.8E-40 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_1327 26abe12edcc0a136247d9c21dba11015 210 Pfam PF05751 FixH 18 173 3.8E-27 T 14-10-2018 IPR008620 Nitrogen fixation protein FixH MCR_0040 dc2dfce1ac58a1a16f672442b1084bc8 471 SUPERFAMILY SSF53850 108 330 2.44E-36 T 14-10-2018 MCR_0040 dc2dfce1ac58a1a16f672442b1084bc8 471 Pfam PF13379 NMT1-like family 106 343 9.2E-73 T 14-10-2018 MCR_0040 dc2dfce1ac58a1a16f672442b1084bc8 471 Gene3D G3DSA:3.40.190.10 112 446 2.2E-101 T 14-10-2018 MCR_0040 dc2dfce1ac58a1a16f672442b1084bc8 471 Gene3D G3DSA:3.40.190.10 198 451 2.2E-101 T 14-10-2018 MCR_0120 ca0c8369e19f212403484c9924d758bf 440 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 17 39 3.6E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MCR_0120 ca0c8369e19f212403484c9924d758bf 440 Pfam PF04261 Dyp-type peroxidase family 93 429 2.4E-95 T 14-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MCR_0120 ca0c8369e19f212403484c9924d758bf 440 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 93 429 7.8E-83 T 14-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MCR_0120 ca0c8369e19f212403484c9924d758bf 440 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 12 440 3.6E-135 T 14-10-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 MCR_0120 ca0c8369e19f212403484c9924d758bf 440 SUPERFAMILY SSF54909 88 433 2.32E-80 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MCR_1369 f4951910fa39b7728486234c6a4825ef 314 Hamap MF_02057 tRNA 5-carboxymethoxyuridine methyltransferase [cmoM]. 59 312 35.915 T 14-10-2018 IPR033664 tRNA 5-carboxymethoxyuridine methyltransferase GO:0008168 MCR_1369 f4951910fa39b7728486234c6a4825ef 314 Gene3D G3DSA:3.40.50.150 65 312 1.5E-46 T 14-10-2018 MCR_1369 f4951910fa39b7728486234c6a4825ef 314 SUPERFAMILY SSF53335 95 288 2.15E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1369 f4951910fa39b7728486234c6a4825ef 314 Pfam PF13847 Methyltransferase domain 102 206 2.9E-13 T 14-10-2018 IPR025714 Methyltransferase domain MCR_1654 9b907ad3bf525e688211fef1e42ee505 339 Pfam PF00294 pfkB family carbohydrate kinase 57 324 3.3E-46 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB MCR_1654 9b907ad3bf525e688211fef1e42ee505 339 SUPERFAMILY SSF53613 1 326 1.18E-67 T 14-10-2018 IPR029056 Ribokinase-like MCR_1654 9b907ad3bf525e688211fef1e42ee505 339 Gene3D G3DSA:3.40.1190.20 5 320 1.2E-75 T 14-10-2018 IPR029056 Ribokinase-like MCR_1654 9b907ad3bf525e688211fef1e42ee505 339 Gene3D G3DSA:3.30.1110.10 12 134 1.2E-75 T 14-10-2018 MCR_1654 9b907ad3bf525e688211fef1e42ee505 339 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 279 292 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MCR_1287 2e1a6926a829a6a4564907841310dba8 590 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 8 581 1.1E-250 T 14-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily MCR_1287 2e1a6926a829a6a4564907841310dba8 590 Pfam PF00474 Sodium:solute symporter family 33 297 1.5E-36 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MCR_1287 2e1a6926a829a6a4564907841310dba8 590 Pfam PF00474 Sodium:solute symporter family 390 506 2.1E-17 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MCR_1287 2e1a6926a829a6a4564907841310dba8 590 Gene3D G3DSA:1.20.1730.10 22 330 1.3E-38 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily MCR_1287 2e1a6926a829a6a4564907841310dba8 590 Gene3D G3DSA:1.20.1730.10 349 569 1.2E-26 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily MCR_1702 34a087db813dae404e0adf294a29fb91 266 SMART SM00535 51 184 1.2E-45 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MCR_1702 34a087db813dae404e0adf294a29fb91 266 Gene3D G3DSA:1.10.1520.10 37 182 1.6E-42 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MCR_1702 34a087db813dae404e0adf294a29fb91 266 Hamap MF_00104 Ribonuclease 3 [rnc]. 39 256 26.221 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MCR_1702 34a087db813dae404e0adf294a29fb91 266 SMART SM00358 191 260 2.3E-11 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain MCR_1702 34a087db813dae404e0adf294a29fb91 266 SUPERFAMILY SSF54768 141 261 3.46E-19 T 14-10-2018 MCR_1702 34a087db813dae404e0adf294a29fb91 266 ProSitePatterns PS00517 Ribonuclease III family signature. 69 77 - T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MCR_1702 34a087db813dae404e0adf294a29fb91 266 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 40 259 1.6E-62 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MCR_1702 34a087db813dae404e0adf294a29fb91 266 Pfam PF00035 Double-stranded RNA binding motif 191 259 1.8E-10 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain MCR_1702 34a087db813dae404e0adf294a29fb91 266 SUPERFAMILY SSF69065 30 193 5.23E-46 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MCR_1702 34a087db813dae404e0adf294a29fb91 266 Pfam PF14622 Ribonuclease-III-like 51 172 1.4E-31 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MCR_1702 34a087db813dae404e0adf294a29fb91 266 Gene3D G3DSA:3.30.160.20 187 264 3.2E-13 T 14-10-2018 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 Gene3D G3DSA:3.30.1490.20 121 190 2.8E-26 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 SMART SM01209 103 296 7.9E-133 T 14-10-2018 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 Gene3D G3DSA:3.90.600.10 329 423 9.4E-35 T 14-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 421 9.2E-174 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 421 41.742 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 SUPERFAMILY SSF51246 328 421 8.63E-30 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 330 419 2.5E-28 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 4.6E-82 T 14-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 Gene3D G3DSA:3.40.50.20 2 95 1.5E-35 T 14-10-2018 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 SUPERFAMILY SSF56059 104 322 3.36E-64 T 14-10-2018 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 Gene3D G3DSA:3.30.470.20 191 328 3.8E-53 T 14-10-2018 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 SMART SM01210 329 421 1.4E-49 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 14-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_0883 4f087313899c7f19a1c6106cd913111b 423 SUPERFAMILY SSF52440 1 103 7.48E-35 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MCR_0883 4f087313899c7f19a1c6106cd913111b 423 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 2.6E-32 T 14-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_1397 85f7adc637be982eaed6d7298ce32cec 230 SUPERFAMILY SSF46626 19 117 4.73E-22 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1397 85f7adc637be982eaed6d7298ce32cec 230 SUPERFAMILY SSF46626 123 228 2.68E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1397 85f7adc637be982eaed6d7298ce32cec 230 Pfam PF00034 Cytochrome c 143 228 4.1E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1397 85f7adc637be982eaed6d7298ce32cec 230 Pfam PF00034 Cytochrome c 37 108 2.4E-8 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1397 85f7adc637be982eaed6d7298ce32cec 230 PIRSF PIRSF000005 1 230 5.9E-48 T 14-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 MCR_1397 85f7adc637be982eaed6d7298ce32cec 230 Gene3D G3DSA:1.10.760.10 118 230 6.7E-22 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1397 85f7adc637be982eaed6d7298ce32cec 230 Gene3D G3DSA:1.10.760.10 38 113 4.0E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 SUPERFAMILY SSF88659 464 538 1.83E-21 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 Gene3D G3DSA:1.10.10.10 541 625 5.1E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 Gene3D G3DSA:1.10.601.10 121 460 3.9E-119 T 14-10-2018 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 Pfam PF00140 Sigma-70 factor, region 1.2 106 136 4.6E-12 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 SUPERFAMILY SSF88946 123 458 3.66E-92 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 415 428 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 Pfam PF04539 Sigma-70 region 3 470 546 8.2E-31 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 13 624 41.855 T 14-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 Pfam PF04545 Sigma-70, region 4 559 612 3.5E-18 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 584 610 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 SUPERFAMILY SSF88659 521 623 8.78E-27 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 PRINTS PR00046 Major sigma-70 factor signature 599 610 4.9E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 PRINTS PR00046 Major sigma-70 factor signature 415 428 4.9E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 PRINTS PR00046 Major sigma-70 factor signature 439 447 4.9E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 PRINTS PR00046 Major sigma-70 factor signature 584 599 4.9E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 PRINTS PR00046 Major sigma-70 factor signature 563 575 4.9E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 Gene3D G3DSA:1.10.10.10 464 540 2.0E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 Pfam PF03979 Sigma-70 factor, region 1.1 14 90 2.5E-25 T 14-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 Pfam PF04546 Sigma-70, non-essential region 147 358 9.1E-54 T 14-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 Gene3D G3DSA:1.10.220.120 11 73 1.1E-24 T 14-10-2018 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 Pfam PF04542 Sigma-70 region 2 391 460 1.7E-21 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 387 623 6.1E-122 T 14-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 MCR_0677 0510ccf1871fc6ca8060b228683adbba 626 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 387 612 2.4E-38 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MCR_1332 a0adb6c46909a861a15f04274d3aeafc 232 Hamap MF_00157 Ribonuclease T [rnt]. 1 232 86.742 T 14-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 MCR_1332 a0adb6c46909a861a15f04274d3aeafc 232 SUPERFAMILY SSF53098 13 205 7.59E-51 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MCR_1332 a0adb6c46909a861a15f04274d3aeafc 232 TIGRFAM TIGR01298 RNaseT: ribonuclease T 13 209 2.0E-84 T 14-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 MCR_1332 a0adb6c46909a861a15f04274d3aeafc 232 SMART SM00479 20 208 2.8E-27 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MCR_1332 a0adb6c46909a861a15f04274d3aeafc 232 Pfam PF00929 Exonuclease 22 199 1.8E-33 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MCR_1332 a0adb6c46909a861a15f04274d3aeafc 232 Gene3D G3DSA:3.30.420.10 10 211 2.7E-48 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 5.4E-227 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 SUPERFAMILY SSF50465 300 394 1.44E-36 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 3.7E-34 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.692 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 SUPERFAMILY SSF50447 205 303 1.53E-30 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 Gene3D G3DSA:3.40.50.300 1 205 2.1E-69 T 14-10-2018 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 4.4E-19 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 3.9E-15 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 SUPERFAMILY SSF52540 6 221 1.39E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.8E-59 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 Gene3D G3DSA:2.40.30.10 208 336 1.3E-54 T 14-10-2018 MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MCR_0250 b6263975c27f7b94affab2cb270c14cc 396 Gene3D G3DSA:2.40.30.10 340 394 6.5E-28 T 14-10-2018 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 5.4E-227 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 SUPERFAMILY SSF50465 300 394 1.44E-36 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 3.7E-34 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.692 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 SUPERFAMILY SSF50447 205 303 1.53E-30 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 Gene3D G3DSA:3.40.50.300 1 205 2.1E-69 T 14-10-2018 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 4.4E-19 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 3.9E-15 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 SUPERFAMILY SSF52540 6 221 1.39E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.8E-59 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 Gene3D G3DSA:2.40.30.10 208 336 1.3E-54 T 14-10-2018 MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MCR_0229 b6263975c27f7b94affab2cb270c14cc 396 Gene3D G3DSA:2.40.30.10 340 394 6.5E-28 T 14-10-2018 MCR_0173 91ee3488985146082b06d8616b8310c7 269 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 65 247 2.1E-69 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_0173 91ee3488985146082b06d8616b8310c7 269 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 82 102 5.7E-51 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_0173 91ee3488985146082b06d8616b8310c7 269 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 141 161 5.7E-51 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_0173 91ee3488985146082b06d8616b8310c7 269 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 120 140 5.7E-51 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_0173 91ee3488985146082b06d8616b8310c7 269 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 176 202 5.7E-51 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_0173 91ee3488985146082b06d8616b8310c7 269 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 65 82 5.7E-51 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_0173 91ee3488985146082b06d8616b8310c7 269 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 224 248 5.7E-51 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_0173 91ee3488985146082b06d8616b8310c7 269 Pfam PF01578 Cytochrome C assembly protein 48 204 2.8E-30 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 Hamap MF_00176 Serine--tRNA ligase [serS]. 22 441 40.448 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 239 419 5.0E-38 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 4.1E-34 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 4.1E-34 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 4.1E-34 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 4.1E-34 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 4.1E-34 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 Gene3D G3DSA:3.30.930.10 126 443 9.3E-122 T 14-10-2018 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 SUPERFAMILY SSF46589 22 133 7.85E-28 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 TIGRFAM TIGR00414 serS: serine--tRNA ligase 22 436 6.0E-169 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 SUPERFAMILY SSF55681 137 437 1.24E-101 T 14-10-2018 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 22 128 7.0E-26 T 14-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 Gene3D G3DSA:1.10.287.40 22 125 1.7E-20 T 14-10-2018 MCR_0535 cd3f1aaec6452674342194bb965a1e7f 443 PIRSF PIRSF001529 22 443 2.4E-180 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 SUPERFAMILY SSF52540 67 773 7.85E-95 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 Gene3D G3DSA:1.20.120.1080 461 576 6.5E-16 T 14-10-2018 MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 SMART SM00847 477 581 1.6E-32 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 Pfam PF00271 Helicase conserved C-terminal domain 301 416 1.2E-9 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 SMART SM00490 316 417 1.3E-10 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 SMART SM00487 67 255 1.3E-28 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 Pfam PF00270 DEAD/DEAH box helicase 77 227 1.6E-5 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 12 648 1.4E-247 T 14-10-2018 IPR010222 RNA helicase HrpA GO:0004004 MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 Pfam PF04408 Helicase associated domain (HA2) 479 609 1.8E-16 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 Gene3D G3DSA:3.40.50.300 249 434 1.1E-48 T 14-10-2018 MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 Pfam PF11898 Domain of unknown function (DUF3418) 786 1385 8.5E-153 T 14-10-2018 IPR024590 RNA helicase HrpA, C-terminal MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 Gene3D G3DSA:3.40.50.300 16 248 6.1E-71 T 14-10-2018 MCR_0976 fb74c49ecc9e923dc619b4145a2eb645 1390 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 696 772 1.8E-15 T 14-10-2018 IPR011709 Domain of unknown function DUF1605 MCR_1472 3ce3222ed1fe57a2eb8b30076d2d3a62 250 Gene3D G3DSA:3.30.70.580 1 73 2.2E-20 T 14-10-2018 MCR_1472 3ce3222ed1fe57a2eb8b30076d2d3a62 250 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 40 54 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MCR_1472 3ce3222ed1fe57a2eb8b30076d2d3a62 250 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 8 192 7.2E-44 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MCR_1472 3ce3222ed1fe57a2eb8b30076d2d3a62 250 SUPERFAMILY SSF55120 4 194 3.52E-33 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1472 3ce3222ed1fe57a2eb8b30076d2d3a62 250 Gene3D G3DSA:3.30.70.1560 74 181 1.4E-35 T 14-10-2018 MCR_1472 3ce3222ed1fe57a2eb8b30076d2d3a62 250 Pfam PF00849 RNA pseudouridylate synthase 4 162 1.7E-13 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0186 435611c814c2aafbed71d3d76cfa6a54 190 SUPERFAMILY SSF89392 19 188 1.65E-26 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MCR_0186 435611c814c2aafbed71d3d76cfa6a54 190 Gene3D G3DSA:2.50.20.10 33 189 1.7E-25 T 14-10-2018 MCR_0186 435611c814c2aafbed71d3d76cfa6a54 190 Pfam PF03550 Outer membrane lipoprotein LolB 40 188 9.4E-32 T 14-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 MCR_0549 d8ba127bb81f58f8aeaa64be24bf5ed5 257 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 148 176 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MCR_0549 d8ba127bb81f58f8aeaa64be24bf5ed5 257 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 257 41.526 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 MCR_0549 d8ba127bb81f58f8aeaa64be24bf5ed5 257 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 104 138 9.3E-7 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_0549 d8ba127bb81f58f8aeaa64be24bf5ed5 257 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 25 52 1.5E-6 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_0549 d8ba127bb81f58f8aeaa64be24bf5ed5 257 PIRSF PIRSF000456 1 257 2.2E-102 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 MCR_0549 d8ba127bb81f58f8aeaa64be24bf5ed5 257 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 15 43 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MCR_0549 d8ba127bb81f58f8aeaa64be24bf5ed5 257 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 3 256 7.2E-97 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 MCR_0549 d8ba127bb81f58f8aeaa64be24bf5ed5 257 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 175 256 9.1E-26 T 14-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 MCR_0549 d8ba127bb81f58f8aeaa64be24bf5ed5 257 Gene3D G3DSA:1.20.1180.10 192 257 3.8E-21 T 14-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 MCR_0549 d8ba127bb81f58f8aeaa64be24bf5ed5 257 Gene3D G3DSA:2.160.10.10 1 190 2.9E-55 T 14-10-2018 MCR_0549 d8ba127bb81f58f8aeaa64be24bf5ed5 257 SUPERFAMILY SSF51161 2 257 1.51E-77 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MCR_1580 78cee44e5b7f9fe6cc6db251aaef69d2 109 Gene3D G3DSA:3.90.470.10 1 109 3.6E-45 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 MCR_1580 78cee44e5b7f9fe6cc6db251aaef69d2 109 SUPERFAMILY SSF54843 1 109 1.11E-41 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 MCR_1580 78cee44e5b7f9fe6cc6db251aaef69d2 109 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 14-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1580 78cee44e5b7f9fe6cc6db251aaef69d2 109 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 4.5E-36 T 14-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MCR_1580 78cee44e5b7f9fe6cc6db251aaef69d2 109 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 109 25.527 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1580 78cee44e5b7f9fe6cc6db251aaef69d2 109 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 3.1E-44 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1572 68f151769e690846b3412ee260e123b2 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 3.6E-25 T 14-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1572 68f151769e690846b3412ee260e123b2 101 Gene3D G3DSA:4.10.830.10 42 101 8.7E-22 T 14-10-2018 MCR_1572 68f151769e690846b3412ee260e123b2 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 27.63 T 14-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid MCR_1572 68f151769e690846b3412ee260e123b2 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 14-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1572 68f151769e690846b3412ee260e123b2 101 SUPERFAMILY SSF57716 2 101 2.49E-38 T 14-10-2018 MCR_0020 7854db07caf4ee7084c484c641687ae8 290 Gene3D G3DSA:3.30.1330.30 14 111 5.7E-16 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like MCR_0020 7854db07caf4ee7084c484c641687ae8 290 SUPERFAMILY SSF55315 29 110 6.83E-12 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like MCR_0020 7854db07caf4ee7084c484c641687ae8 290 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 37 281 1.8E-64 T 14-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 MCR_0020 7854db07caf4ee7084c484c641687ae8 290 SUPERFAMILY SSF75217 127 282 5.62E-45 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MCR_0020 7854db07caf4ee7084c484c641687ae8 290 Pfam PF00588 SpoU rRNA Methylase family 131 275 1.9E-35 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MCR_0020 7854db07caf4ee7084c484c641687ae8 290 SMART SM00967 37 116 6.6E-11 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MCR_0020 7854db07caf4ee7084c484c641687ae8 290 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 38 112 6.6E-10 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MCR_0020 7854db07caf4ee7084c484c641687ae8 290 Gene3D G3DSA:3.40.1280.10 114 287 8.8E-49 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MCR_1722 9aba82da20bb17f5c0a1346a81960f2e 331 Pfam PF08402 TOBE domain 256 321 4.0E-6 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MCR_1722 9aba82da20bb17f5c0a1346a81960f2e 331 SUPERFAMILY SSF52540 4 242 8.87E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1722 9aba82da20bb17f5c0a1346a81960f2e 331 SUPERFAMILY SSF50331 249 330 8.5E-6 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MCR_1722 9aba82da20bb17f5c0a1346a81960f2e 331 Gene3D G3DSA:3.40.50.300 1 238 7.7E-80 T 14-10-2018 MCR_1722 9aba82da20bb17f5c0a1346a81960f2e 331 Pfam PF00005 ABC transporter 20 161 4.9E-38 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1722 9aba82da20bb17f5c0a1346a81960f2e 331 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1722 9aba82da20bb17f5c0a1346a81960f2e 331 SMART SM00382 28 211 2.0E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1487 cf8daf480d34f6ac2d86fa892948542c 398 Gene3D G3DSA:3.30.9.50 83 277 9.5E-78 T 14-10-2018 MCR_1487 cf8daf480d34f6ac2d86fa892948542c 398 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 9 398 3.6E-106 T 14-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MCR_1487 cf8daf480d34f6ac2d86fa892948542c 398 Pfam PF01494 FAD binding domain 9 347 9.4E-24 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 MCR_1487 cf8daf480d34f6ac2d86fa892948542c 398 Gene3D G3DSA:3.50.50.60 9 345 9.5E-78 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1487 cf8daf480d34f6ac2d86fa892948542c 398 SUPERFAMILY SSF51905 9 393 2.09E-51 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1487 cf8daf480d34f6ac2d86fa892948542c 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 1.2E-11 T 14-10-2018 MCR_1487 cf8daf480d34f6ac2d86fa892948542c 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 1.2E-11 T 14-10-2018 MCR_1487 cf8daf480d34f6ac2d86fa892948542c 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 164 179 1.2E-11 T 14-10-2018 MCR_1487 cf8daf480d34f6ac2d86fa892948542c 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 319 1.2E-11 T 14-10-2018 MCR_0183 956d562e7271e45686386ff88577be15 171 Pfam PF01292 Prokaryotic cytochrome b561 11 170 1.6E-17 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MCR_0183 956d562e7271e45686386ff88577be15 171 SUPERFAMILY SSF81342 7 171 2.51E-23 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MCR_1562 62e37a316aed200f53c683db07f3f73f 213 Pfam PF01479 S4 domain 97 124 1.3E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1562 62e37a316aed200f53c683db07f3f73f 213 Gene3D G3DSA:1.10.1050.10 6 213 4.1E-71 T 14-10-2018 MCR_1562 62e37a316aed200f53c683db07f3f73f 213 SMART SM01390 3 96 1.6E-41 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MCR_1562 62e37a316aed200f53c683db07f3f73f 213 SMART SM00363 97 167 1.1E-9 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1562 62e37a316aed200f53c683db07f3f73f 213 Gene3D G3DSA:3.10.290.10 96 198 4.1E-71 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MCR_1562 62e37a316aed200f53c683db07f3f73f 213 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 213 2.6E-76 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MCR_1562 62e37a316aed200f53c683db07f3f73f 213 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 213 34.298 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MCR_1562 62e37a316aed200f53c683db07f3f73f 213 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 14-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1562 62e37a316aed200f53c683db07f3f73f 213 SUPERFAMILY SSF55174 3 213 5.1E-61 T 14-10-2018 MCR_1562 62e37a316aed200f53c683db07f3f73f 213 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 4.6E-29 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MCR_0761 7fe3c9c2829da88126bc3d698b903944 225 Gene3D G3DSA:2.40.33.20 6 224 6.1E-56 T 14-10-2018 MCR_0761 7fe3c9c2829da88126bc3d698b903944 225 SUPERFAMILY SSF50800 7 220 1.88E-47 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MCR_0761 7fe3c9c2829da88126bc3d698b903944 225 Pfam PF03473 MOSC domain 53 171 5.7E-14 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MCR_0302 9cdec7e90d4eacbc1ea97512f3d99b04 98 Gene3D G3DSA:3.40.50.1000 1 78 8.9E-24 T 14-10-2018 IPR023214 HAD superfamily MCR_0302 9cdec7e90d4eacbc1ea97512f3d99b04 98 Pfam PF08282 haloacid dehalogenase-like hydrolase 3 72 4.2E-22 T 14-10-2018 MCR_0302 9cdec7e90d4eacbc1ea97512f3d99b04 98 SUPERFAMILY SSF56784 3 74 4.29E-24 T 14-10-2018 IPR036412 HAD-like superfamily MCR_1881 5ce44c1a1046a79477713df4f77af374 417 PIRSF PIRSF000521 1 171 4.6E-6 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MCR_1881 5ce44c1a1046a79477713df4f77af374 417 PIRSF PIRSF000521 172 413 6.9E-36 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MCR_1881 5ce44c1a1046a79477713df4f77af374 417 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 231 268 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MCR_1881 5ce44c1a1046a79477713df4f77af374 417 SUPERFAMILY SSF53383 8 411 4.81E-119 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_1881 5ce44c1a1046a79477713df4f77af374 417 Gene3D G3DSA:3.40.640.10 64 316 1.9E-149 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_1881 5ce44c1a1046a79477713df4f77af374 417 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 10 410 2.2E-201 T 14-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MCR_1881 5ce44c1a1046a79477713df4f77af374 417 Pfam PF00202 Aminotransferase class-III 21 409 3.1E-118 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MCR_1881 5ce44c1a1046a79477713df4f77af374 417 Gene3D G3DSA:3.90.1150.10 18 402 1.9E-149 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 Hamap MF_00050 Elongation factor Ts [tsf]. 1 288 76.724 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 Gene3D G3DSA:3.30.479.20 57 148 9.3E-27 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 SUPERFAMILY SSF54713 150 286 1.57E-48 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 Pfam PF00889 Elongation factor TS 71 270 2.1E-67 T 14-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 SUPERFAMILY SSF46934 4 54 6.63E-18 T 14-10-2018 IPR009060 UBA-like superfamily GO:0005515 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 SUPERFAMILY SSF54713 56 146 2.09E-20 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 286 1.9E-100 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 Gene3D G3DSA:1.10.8.10 1 56 4.8E-26 T 14-10-2018 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 Gene3D G3DSA:3.30.479.20 153 269 4.6E-40 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MCR_0277 c508f0b3233a55b3893960d89f22020e 292 Gene3D G3DSA:1.10.286.20 189 235 4.6E-40 T 14-10-2018 MCR_1341 5573b953095aaa49cb68834c32484fad 228 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 216 4.7E-45 T 14-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 MCR_1341 5573b953095aaa49cb68834c32484fad 228 Gene3D G3DSA:3.30.420.40 4 216 8.8E-49 T 14-10-2018 MCR_1341 5573b953095aaa49cb68834c32484fad 228 Gene3D G3DSA:3.30.420.40 96 185 8.8E-49 T 14-10-2018 MCR_1341 5573b953095aaa49cb68834c32484fad 228 SUPERFAMILY SSF53067 4 106 1.73E-19 T 14-10-2018 MCR_1341 5573b953095aaa49cb68834c32484fad 228 SUPERFAMILY SSF53067 114 214 4.79E-11 T 14-10-2018 MCR_1341 5573b953095aaa49cb68834c32484fad 228 Pfam PF00814 Glycoprotease family 37 140 1.0E-16 T 14-10-2018 IPR000905 Gcp-like domain MCR_0879 70dd8b60de4fce55e0d7eac5b8fad494 432 SUPERFAMILY SSF53098 5 147 1.52E-47 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MCR_0879 70dd8b60de4fce55e0d7eac5b8fad494 432 Hamap MF_00042 Ribonuclease H [rnhA]. 2 155 26.908 T 14-10-2018 IPR022892 Ribonuclease HI GO:0004523 MCR_0879 70dd8b60de4fce55e0d7eac5b8fad494 432 Gene3D G3DSA:3.30.420.10 2 153 1.3E-53 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MCR_0879 70dd8b60de4fce55e0d7eac5b8fad494 432 SUPERFAMILY SSF53098 207 383 1.31E-50 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MCR_0879 70dd8b60de4fce55e0d7eac5b8fad494 432 SMART SM00479 212 383 2.3E-49 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MCR_0879 70dd8b60de4fce55e0d7eac5b8fad494 432 Pfam PF00929 Exonuclease 214 374 1.3E-34 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MCR_0879 70dd8b60de4fce55e0d7eac5b8fad494 432 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 214 403 1.9E-51 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_0879 70dd8b60de4fce55e0d7eac5b8fad494 432 Gene3D G3DSA:3.30.420.10 207 390 1.9E-51 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MCR_0879 70dd8b60de4fce55e0d7eac5b8fad494 432 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 212 422 2.3E-74 T 14-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_0879 70dd8b60de4fce55e0d7eac5b8fad494 432 Pfam PF00075 RNase H 6 146 3.8E-41 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 MCR_0875 e14ff87bceed40f06efc9e1425acae5b 97 Pfam PF03795 YCII-related domain 3 91 6.2E-19 T 14-10-2018 IPR005545 YCII-related MCR_0875 e14ff87bceed40f06efc9e1425acae5b 97 Gene3D G3DSA:3.30.70.1060 1 95 3.1E-29 T 14-10-2018 MCR_0875 e14ff87bceed40f06efc9e1425acae5b 97 SUPERFAMILY SSF54909 1 94 1.05E-25 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MCR_0036 c35d116581909faaa327e8911fd15ed0 558 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 55 556 6.2E-144 T 14-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MCR_0036 c35d116581909faaa327e8911fd15ed0 558 SUPERFAMILY SSF55931 51 555 2.75E-167 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MCR_0036 c35d116581909faaa327e8911fd15ed0 558 Pfam PF04262 Glutamate-cysteine ligase 57 420 6.1E-137 T 14-10-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MCR_0036 c35d116581909faaa327e8911fd15ed0 558 Gene3D G3DSA:3.30.590.20 57 558 2.5E-169 T 14-10-2018 MCR_0036 c35d116581909faaa327e8911fd15ed0 558 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 18 558 165.907 T 14-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MCR_1209 55c68748707b5deda2b9d116ed92697f 250 SUPERFAMILY SSF161098 51 235 1.7E-25 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1209 55c68748707b5deda2b9d116ed92697f 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 243 9.9E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_1209 55c68748707b5deda2b9d116ed92697f 250 Gene3D G3DSA:1.10.3720.10 47 245 2.2E-23 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1389 392bc5aef978ea8f43169daf0c80be78 561 Gene3D G3DSA:3.40.50.980 60 382 1.4E-108 T 14-10-2018 MCR_1389 392bc5aef978ea8f43169daf0c80be78 561 SUPERFAMILY SSF56801 6 560 4.19E-144 T 14-10-2018 MCR_1389 392bc5aef978ea8f43169daf0c80be78 561 Gene3D G3DSA:2.30.38.10 385 462 1.4E-108 T 14-10-2018 MCR_1389 392bc5aef978ea8f43169daf0c80be78 561 Pfam PF00501 AMP-binding enzyme 57 469 2.2E-104 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MCR_1389 392bc5aef978ea8f43169daf0c80be78 561 Pfam PF13193 AMP-binding enzyme C-terminal domain 478 552 1.1E-20 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MCR_1389 392bc5aef978ea8f43169daf0c80be78 561 Gene3D G3DSA:3.40.50.980 63 235 1.4E-108 T 14-10-2018 MCR_1389 392bc5aef978ea8f43169daf0c80be78 561 ProSitePatterns PS00455 Putative AMP-binding domain signature. 219 230 - T 14-10-2018 IPR020845 AMP-binding, conserved site MCR_1389 392bc5aef978ea8f43169daf0c80be78 561 Gene3D G3DSA:3.30.300.310 465 561 3.0E-31 T 14-10-2018 MCR_0764 0e468759f7be29687b4d880904a66349 656 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 39 144 4.5E-15 T 14-10-2018 IPR029095 NarX-like, N-terminal MCR_0764 0e468759f7be29687b4d880904a66349 656 Gene3D G3DSA:3.30.565.10 516 652 1.1E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0764 0e468759f7be29687b4d880904a66349 656 SUPERFAMILY SSF55874 524 649 2.62E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0764 0e468759f7be29687b4d880904a66349 656 SMART SM00387 555 653 2.7E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0764 0e468759f7be29687b4d880904a66349 656 PIRSF PIRSF003167 3 656 9.2E-158 T 14-10-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 MCR_0764 0e468759f7be29687b4d880904a66349 656 Pfam PF07730 Histidine kinase 436 514 8.1E-13 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MCR_0764 0e468759f7be29687b4d880904a66349 656 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 556 649 1.6E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0764 0e468759f7be29687b4d880904a66349 656 Gene3D G3DSA:1.20.120.960 45 168 6.2E-7 T 14-10-2018 MCR_0144 a89c812620c4e670a5dffaa7242b43be 322 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 203 319 9.0E-29 T 14-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MCR_0144 a89c812620c4e670a5dffaa7242b43be 322 SUPERFAMILY SSF64383 187 319 3.53E-25 T 14-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 MCR_0144 a89c812620c4e670a5dffaa7242b43be 322 SMART SM00771 184 316 2.1E-14 T 14-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MCR_0144 a89c812620c4e670a5dffaa7242b43be 322 Gene3D G3DSA:3.30.1400.10 183 322 5.0E-29 T 14-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 MCR_0144 a89c812620c4e670a5dffaa7242b43be 322 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 187 313 2.6E-29 T 14-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MCR_1283 aca539378112854bee088fdd59814fb4 950 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 9 949 24.275 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MCR_1283 aca539378112854bee088fdd59814fb4 950 Gene3D G3DSA:3.90.1150.10 756 885 1.3E-39 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_1283 aca539378112854bee088fdd59814fb4 950 Gene3D G3DSA:3.40.640.10 96 353 1.9E-96 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_1283 aca539378112854bee088fdd59814fb4 950 Gene3D G3DSA:3.40.640.10 515 741 1.6E-58 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_1283 aca539378112854bee088fdd59814fb4 950 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 18 943 0.0 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MCR_1283 aca539378112854bee088fdd59814fb4 950 Pfam PF01212 Beta-eliminating lyase 538 705 2.7E-6 T 14-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 MCR_1283 aca539378112854bee088fdd59814fb4 950 Pfam PF02347 Glycine cleavage system P-protein 17 440 7.7E-172 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MCR_1283 aca539378112854bee088fdd59814fb4 950 SUPERFAMILY SSF53383 469 944 5.5E-95 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_1283 aca539378112854bee088fdd59814fb4 950 SUPERFAMILY SSF53383 17 440 2.39E-93 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_1021 e59777fda744b04b5d8dc36fdfe08358 170 Gene3D G3DSA:3.10.129.10 23 163 4.1E-33 T 14-10-2018 MCR_1021 e59777fda744b04b5d8dc36fdfe08358 170 Pfam PF13279 Thioesterase-like superfamily 34 161 2.3E-10 T 14-10-2018 MCR_1021 e59777fda744b04b5d8dc36fdfe08358 170 PIRSF PIRSF003230 18 170 2.0E-40 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MCR_1021 e59777fda744b04b5d8dc36fdfe08358 170 SUPERFAMILY SSF54637 23 164 9.51E-28 T 14-10-2018 IPR029069 HotDog domain superfamily MCR_0492 4d1a3150386d7ab958577d3f09c7b46b 759 Pfam PF00593 TonB dependent receptor 309 758 2.6E-35 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MCR_0492 4d1a3150386d7ab958577d3f09c7b46b 759 Gene3D G3DSA:2.170.130.10 40 150 2.2E-36 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MCR_0492 4d1a3150386d7ab958577d3f09c7b46b 759 SUPERFAMILY SSF56935 46 758 2.75E-62 T 14-10-2018 MCR_0492 4d1a3150386d7ab958577d3f09c7b46b 759 Pfam PF07715 TonB-dependent Receptor Plug Domain 46 145 2.4E-12 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain MCR_0492 4d1a3150386d7ab958577d3f09c7b46b 759 Gene3D G3DSA:2.40.170.20 151 305 3.5E-40 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MCR_0492 4d1a3150386d7ab958577d3f09c7b46b 759 Gene3D G3DSA:2.40.170.20 306 759 7.4E-134 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MCR_0466 81bef7a3e2dbc00ca5f6cfd4fd74df15 632 Gene3D G3DSA:3.50.30.80 438 589 1.1E-53 T 14-10-2018 MCR_0466 81bef7a3e2dbc00ca5f6cfd4fd74df15 632 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MCR_0466 81bef7a3e2dbc00ca5f6cfd4fd74df15 632 Pfam PF00920 Dehydratase family 34 624 1.2E-217 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MCR_0466 81bef7a3e2dbc00ca5f6cfd4fd74df15 632 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 526 537 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MCR_0466 81bef7a3e2dbc00ca5f6cfd4fd74df15 632 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 627 44.528 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MCR_0466 81bef7a3e2dbc00ca5f6cfd4fd74df15 632 SUPERFAMILY SSF52016 438 629 3.61E-60 T 14-10-2018 MCR_0466 81bef7a3e2dbc00ca5f6cfd4fd74df15 632 SUPERFAMILY SSF143975 4 437 3.53E-131 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MCR_0466 81bef7a3e2dbc00ca5f6cfd4fd74df15 632 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 627 2.5E-247 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MCR_1730 5aaa685d36e42c587d943409bae154bb 256 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 27 253 3.1E-96 T 14-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 MCR_1730 5aaa685d36e42c587d943409bae154bb 256 Pfam PF00072 Response regulator receiver domain 31 143 3.0E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_1730 5aaa685d36e42c587d943409bae154bb 256 SUPERFAMILY SSF52172 24 151 3.7E-39 T 14-10-2018 IPR011006 CheY-like superfamily MCR_1730 5aaa685d36e42c587d943409bae154bb 256 SMART SM00862 177 252 3.4E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MCR_1730 5aaa685d36e42c587d943409bae154bb 256 Gene3D G3DSA:1.10.10.10 156 255 1.6E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_1730 5aaa685d36e42c587d943409bae154bb 256 SMART SM00448 29 143 9.0E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_1730 5aaa685d36e42c587d943409bae154bb 256 Gene3D G3DSA:3.40.50.2300 23 155 3.3E-36 T 14-10-2018 MCR_1730 5aaa685d36e42c587d943409bae154bb 256 Pfam PF00486 Transcriptional regulatory protein, C terminal 177 252 1.9E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MCR_1730 5aaa685d36e42c587d943409bae154bb 256 SUPERFAMILY SSF46894 154 252 1.5E-28 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MCR_0050 92059c62920fb5efd71bca13f0b82824 383 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 354 3.9E-135 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MCR_0050 92059c62920fb5efd71bca13f0b82824 383 Pfam PF01556 DnaJ C terminal domain 128 339 2.6E-44 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal MCR_0050 92059c62920fb5efd71bca13f0b82824 383 SUPERFAMILY SSF46565 3 114 6.67E-35 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MCR_0050 92059c62920fb5efd71bca13f0b82824 383 Gene3D G3DSA:2.60.260.20 261 370 6.6E-29 T 14-10-2018 MCR_0050 92059c62920fb5efd71bca13f0b82824 383 SUPERFAMILY SSF49493 120 272 1.05E-20 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MCR_0050 92059c62920fb5efd71bca13f0b82824 383 SUPERFAMILY SSF57938 140 216 1.31E-21 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily MCR_0050 92059c62920fb5efd71bca13f0b82824 383 Gene3D G3DSA:2.10.230.10 153 217 6.1E-21 T 14-10-2018 MCR_0050 92059c62920fb5efd71bca13f0b82824 383 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 377 40.544 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MCR_0050 92059c62920fb5efd71bca13f0b82824 383 Pfam PF00226 DnaJ domain 4 66 8.3E-27 T 14-10-2018 IPR001623 DnaJ domain MCR_0050 92059c62920fb5efd71bca13f0b82824 383 SMART SM00271 3 61 1.8E-30 T 14-10-2018 IPR001623 DnaJ domain MCR_0050 92059c62920fb5efd71bca13f0b82824 383 Gene3D G3DSA:1.10.287.110 1 114 8.5E-37 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MCR_0050 92059c62920fb5efd71bca13f0b82824 383 Pfam PF00684 DnaJ central domain 153 213 4.4E-15 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MCR_0050 92059c62920fb5efd71bca13f0b82824 383 SUPERFAMILY SSF49493 265 350 7.98E-22 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MCR_0050 92059c62920fb5efd71bca13f0b82824 383 PRINTS PR00625 DnaJ domain signature 61 80 4.5E-29 T 14-10-2018 IPR001623 DnaJ domain MCR_0050 92059c62920fb5efd71bca13f0b82824 383 PRINTS PR00625 DnaJ domain signature 6 24 4.5E-29 T 14-10-2018 IPR001623 DnaJ domain MCR_0050 92059c62920fb5efd71bca13f0b82824 383 PRINTS PR00625 DnaJ domain signature 24 39 4.5E-29 T 14-10-2018 IPR001623 DnaJ domain MCR_0050 92059c62920fb5efd71bca13f0b82824 383 PRINTS PR00625 DnaJ domain signature 41 61 4.5E-29 T 14-10-2018 IPR001623 DnaJ domain MCR_0854 cc127b6921d04ec1c9faaeafb4c1b3d1 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 126 6.9E-57 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MCR_0854 cc127b6921d04ec1c9faaeafb4c1b3d1 127 Pfam PF02261 Aspartate decarboxylase 1 114 8.2E-53 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MCR_0854 cc127b6921d04ec1c9faaeafb4c1b3d1 127 SUPERFAMILY SSF50692 1 122 9.44E-51 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MCR_0854 cc127b6921d04ec1c9faaeafb4c1b3d1 127 PIRSF PIRSF006246 1 126 7.5E-54 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MCR_0854 cc127b6921d04ec1c9faaeafb4c1b3d1 127 Gene3D G3DSA:2.40.40.20 1 125 2.5E-54 T 14-10-2018 MCR_0854 cc127b6921d04ec1c9faaeafb4c1b3d1 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 6.0E-38 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MCR_0854 cc127b6921d04ec1c9faaeafb4c1b3d1 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 72.626 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MCR_0848 cfde1e69a2d2655f4f507024e3b4134d 188 SUPERFAMILY SSF46785 96 169 5.17E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0848 cfde1e69a2d2655f4f507024e3b4134d 188 SUPERFAMILY SSF46785 19 91 6.39E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0848 cfde1e69a2d2655f4f507024e3b4134d 188 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 21 188 2.7E-37 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MCR_0848 cfde1e69a2d2655f4f507024e3b4134d 188 PIRSF PIRSF019345 3 187 1.8E-50 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MCR_0848 cfde1e69a2d2655f4f507024e3b4134d 188 Gene3D G3DSA:1.10.10.10 92 187 5.0E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0848 cfde1e69a2d2655f4f507024e3b4134d 188 Gene3D G3DSA:1.10.10.10 12 91 2.4E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0848 cfde1e69a2d2655f4f507024e3b4134d 188 Pfam PF04079 Segregation and condensation complex subunit ScpB 22 178 3.2E-47 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MCR_1133 2c44082f21b6c7880f9eecdf1c8fa600 197 SUPERFAMILY SSF47616 67 194 9.24E-33 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MCR_1133 2c44082f21b6c7880f9eecdf1c8fa600 197 Gene3D G3DSA:1.20.1050.10 74 197 1.2E-50 T 14-10-2018 MCR_1133 2c44082f21b6c7880f9eecdf1c8fa600 197 Gene3D G3DSA:3.40.30.10 3 73 7.5E-13 T 14-10-2018 MCR_1133 2c44082f21b6c7880f9eecdf1c8fa600 197 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 6 195 1.6E-66 T 14-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 MCR_1133 2c44082f21b6c7880f9eecdf1c8fa600 197 Pfam PF13410 Glutathione S-transferase, C-terminal domain 124 155 5.2E-6 T 14-10-2018 MCR_1133 2c44082f21b6c7880f9eecdf1c8fa600 197 SUPERFAMILY SSF52833 5 74 4.58E-11 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_1133 2c44082f21b6c7880f9eecdf1c8fa600 197 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 65 5.4E-5 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MCR_0666 e7f11149c4c8275e7c11219b1cf58622 236 SUPERFAMILY SSF140804 120 220 3.27E-26 T 14-10-2018 IPR027405 YidB-like MCR_0666 e7f11149c4c8275e7c11219b1cf58622 236 Pfam PF06078 Bacterial protein of unknown function (DUF937) 61 210 2.9E-27 T 14-10-2018 IPR009282 Protein of unknown function DUF937 MCR_0666 e7f11149c4c8275e7c11219b1cf58622 236 Gene3D G3DSA:1.10.10.690 91 233 3.4E-29 T 14-10-2018 IPR027405 YidB-like MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 Gene3D G3DSA:3.30.70.1440 673 869 0.0 T 14-10-2018 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1047 0.0 T 14-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 PRINTS PR00702 Acriflavin resistance protein family signature 364 385 1.9E-107 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 PRINTS PR00702 Acriflavin resistance protein family signature 392 416 1.9E-107 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 PRINTS PR00702 Acriflavin resistance protein family signature 337 360 1.9E-107 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.9E-107 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 PRINTS PR00702 Acriflavin resistance protein family signature 555 572 1.9E-107 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.9E-107 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.9E-107 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.9E-107 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 PRINTS PR00702 Acriflavin resistance protein family signature 624 638 1.9E-107 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 SUPERFAMILY SSF82693 676 860 8.11E-26 T 14-10-2018 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 Gene3D G3DSA:3.30.70.1320 133 333 0.0 T 14-10-2018 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 Gene3D G3DSA:3.30.70.1430 38 821 0.0 T 14-10-2018 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 SUPERFAMILY SSF82693 135 331 2.22E-25 T 14-10-2018 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 Pfam PF00873 AcrB/AcrD/AcrF family 1 1029 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 SUPERFAMILY SSF82866 837 1029 6.67E-41 T 14-10-2018 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 SUPERFAMILY SSF82866 297 499 1.83E-44 T 14-10-2018 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 Gene3D G3DSA:1.20.1640.10 516 1026 0.0 T 14-10-2018 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 SUPERFAMILY SSF82714 182 273 8.76E-20 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 SUPERFAMILY SSF82714 726 812 5.62E-18 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 Gene3D G3DSA:3.30.70.1430 570 672 0.0 T 14-10-2018 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 Gene3D G3DSA:1.20.1640.10 8 515 0.0 T 14-10-2018 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 Gene3D G3DSA:3.30.2090.10 725 813 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 SUPERFAMILY SSF82693 38 131 1.92E-28 T 14-10-2018 MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 Gene3D G3DSA:3.30.2090.10 179 276 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MCR_0475 85a9d7b14c4b857d8fa949988a14859d 1051 SUPERFAMILY SSF82693 568 675 5.75E-30 T 14-10-2018 MCR_1537 0d220bad25074456868504e65b38b440 469 SUPERFAMILY SSF51984 3 89 9.29E-20 T 14-10-2018 MCR_1537 0d220bad25074456868504e65b38b440 469 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 3 461 31.669 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MCR_1537 0d220bad25074456868504e65b38b440 469 Gene3D G3DSA:3.40.50.720 1 89 1.4E-25 T 14-10-2018 MCR_1537 0d220bad25074456868504e65b38b440 469 Pfam PF08245 Mur ligase middle domain 115 295 6.1E-27 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MCR_1537 0d220bad25074456868504e65b38b440 469 SUPERFAMILY SSF53244 315 461 8.24E-35 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_1537 0d220bad25074456868504e65b38b440 469 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 6 459 1.1E-114 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MCR_1537 0d220bad25074456868504e65b38b440 469 Gene3D G3DSA:3.90.190.20 316 458 1.5E-35 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_1537 0d220bad25074456868504e65b38b440 469 SUPERFAMILY SSF53623 107 313 1.14E-45 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_1537 0d220bad25074456868504e65b38b440 469 Gene3D G3DSA:3.40.1190.10 100 315 1.8E-56 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_1537 0d220bad25074456868504e65b38b440 469 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 392 3.3E-7 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MCR_1052 cf81cebaaf9a8a018014beaca8c4ece4 355 Gene3D G3DSA:3.10.290.10 40 110 1.4E-19 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MCR_1052 cf81cebaaf9a8a018014beaca8c4ece4 355 Gene3D G3DSA:3.30.2350.10 120 353 3.9E-69 T 14-10-2018 MCR_1052 cf81cebaaf9a8a018014beaca8c4ece4 355 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 51 350 1.6E-94 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1052 cf81cebaaf9a8a018014beaca8c4ece4 355 Pfam PF00849 RNA pseudouridylate synthase 129 281 2.3E-28 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1052 cf81cebaaf9a8a018014beaca8c4ece4 355 Pfam PF01479 S4 domain 56 100 6.6E-11 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1052 cf81cebaaf9a8a018014beaca8c4ece4 355 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 171 185 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1052 cf81cebaaf9a8a018014beaca8c4ece4 355 SUPERFAMILY SSF55174 54 141 1.48E-11 T 14-10-2018 MCR_1052 cf81cebaaf9a8a018014beaca8c4ece4 355 SUPERFAMILY SSF55120 112 351 5.55E-75 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1052 cf81cebaaf9a8a018014beaca8c4ece4 355 SMART SM00363 55 115 2.4E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0389 591ce1fa660887dcee2dd05577c55dba 185 Gene3D G3DSA:2.40.30.60 10 105 5.6E-27 T 14-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 MCR_0389 591ce1fa660887dcee2dd05577c55dba 185 SUPERFAMILY SSF50447 17 105 9.18E-20 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MCR_0389 591ce1fa660887dcee2dd05577c55dba 185 SUPERFAMILY SSF50346 111 184 4.51E-18 T 14-10-2018 IPR011033 PRC-barrel-like superfamily MCR_0389 591ce1fa660887dcee2dd05577c55dba 185 Pfam PF05239 PRC-barrel domain 109 179 6.4E-10 T 14-10-2018 IPR027275 PRC-barrel domain MCR_0389 591ce1fa660887dcee2dd05577c55dba 185 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 18 184 1.5E-42 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MCR_0389 591ce1fa660887dcee2dd05577c55dba 185 Gene3D G3DSA:2.30.30.240 111 185 1.6E-26 T 14-10-2018 MCR_0389 591ce1fa660887dcee2dd05577c55dba 185 Pfam PF01782 RimM N-terminal domain 21 100 1.9E-19 T 14-10-2018 IPR002676 RimM, N-terminal GO:0006364 MCR_0389 591ce1fa660887dcee2dd05577c55dba 185 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 18 185 20.803 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MCR_1445 48239593238ff5e6f83e5df340cd6f31 669 Pfam PF01464 Transglycosylase SLT domain 516 619 1.6E-26 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 MCR_1445 48239593238ff5e6f83e5df340cd6f31 669 SUPERFAMILY SSF53955 508 659 6.57E-42 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MCR_1445 48239593238ff5e6f83e5df340cd6f31 669 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 530 558 - T 14-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MCR_1445 48239593238ff5e6f83e5df340cd6f31 669 SUPERFAMILY SSF48435 43 506 5.49E-68 T 14-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 MCR_1445 48239593238ff5e6f83e5df340cd6f31 669 Gene3D G3DSA:1.25.20.10 32 408 1.3E-58 T 14-10-2018 MCR_1445 48239593238ff5e6f83e5df340cd6f31 669 Gene3D G3DSA:1.10.530.10 503 662 4.5E-43 T 14-10-2018 MCR_1884 469d7265a882943c25c5927bb61c20dc 116 SUPERFAMILY SSF54506 77 116 5.02E-10 T 14-10-2018 MCR_1884 469d7265a882943c25c5927bb61c20dc 116 Pfam PF04303 PrpF protein 15 115 6.8E-25 T 14-10-2018 IPR007400 PrpF protein MCR_1884 469d7265a882943c25c5927bb61c20dc 116 Gene3D G3DSA:3.10.310.10 70 116 3.8E-10 T 14-10-2018 MCR_1884 469d7265a882943c25c5927bb61c20dc 116 SUPERFAMILY SSF54506 7 73 3.92E-6 T 14-10-2018 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 SUPERFAMILY SSF101967 156 329 3.66E-27 T 14-10-2018 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 304 347 5.7E-11 T 14-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 Gene3D G3DSA:1.20.5.170 310 359 6.0E-16 T 14-10-2018 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 265 878 5.0E-7 T 14-10-2018 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 SUPERFAMILY SSF54523 863 954 5.02E-16 T 14-10-2018 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 PRINTS PR01804 Ubiquitous surface protein signature 716 738 6.0E-57 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 PRINTS PR01804 Ubiquitous surface protein signature 699 713 6.0E-57 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 PRINTS PR01804 Ubiquitous surface protein signature 923 936 6.0E-57 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 PRINTS PR01804 Ubiquitous surface protein signature 500 519 6.0E-57 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 PRINTS PR01804 Ubiquitous surface protein signature 530 548 6.0E-57 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 PRINTS PR01804 Ubiquitous surface protein signature 869 883 6.0E-57 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 Pfam PF05658 Head domain of trimeric autotransporter adhesin 206 231 5.4E-6 T 14-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 SUPERFAMILY SSF69349 61 155 1.49E-5 T 14-10-2018 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 Gene3D G3DSA:3.30.1300.30 853 954 2.6E-19 T 14-10-2018 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 Pfam PF06435 Repeat of unknown function (DUF1079) 595 625 4.1E-14 T 14-10-2018 IPR010494 Repeat of unknown function DUF1079 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 Pfam PF06435 Repeat of unknown function (DUF1079) 478 498 1.7E-7 T 14-10-2018 IPR010494 Repeat of unknown function DUF1079 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 Pfam PF06435 Repeat of unknown function (DUF1079) 708 737 5.6E-14 T 14-10-2018 IPR010494 Repeat of unknown function DUF1079 MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 Gene3D G3DSA:2.150.10.10 150 309 5.4E-54 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 Pfam PF03895 YadA-like membrane anchor domain 894 954 7.4E-12 T 14-10-2018 IPR005594 YadA-like, C-terminal MCR_1198 0a2a5c0deb9e673ce9eb50ca214e14b7 955 Gene3D G3DSA:2.150.10.10 43 145 2.5E-13 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MCR_0822 c0176db54e991ee2320e5a74f01312fd 402 Gene3D G3DSA:3.20.20.70 6 389 2.4E-130 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0822 c0176db54e991ee2320e5a74f01312fd 402 PIRSF PIRSF000138 1 387 4.6E-123 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MCR_0822 c0176db54e991ee2320e5a74f01312fd 402 Pfam PF01070 FMN-dependent dehydrogenase 17 382 1.1E-130 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 MCR_0822 c0176db54e991ee2320e5a74f01312fd 402 SUPERFAMILY SSF51395 7 382 4.4E-106 T 14-10-2018 MCR_0822 c0176db54e991ee2320e5a74f01312fd 402 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 277 283 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MCR_1546 a5ce6dd930c2465fe174dc2dc288fe52 340 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 179 4.7E-75 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MCR_1546 a5ce6dd930c2465fe174dc2dc288fe52 340 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 2.7E-62 T 14-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MCR_1546 a5ce6dd930c2465fe174dc2dc288fe52 340 Gene3D G3DSA:1.10.3730.40 184 340 1.4E-73 T 14-10-2018 MCR_1546 a5ce6dd930c2465fe174dc2dc288fe52 340 SUPERFAMILY SSF48179 185 334 5.44E-68 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MCR_1546 a5ce6dd930c2465fe174dc2dc288fe52 340 SUPERFAMILY SSF51735 4 184 3.2E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1546 a5ce6dd930c2465fe174dc2dc288fe52 340 Gene3D G3DSA:3.40.50.720 1 183 1.3E-78 T 14-10-2018 MCR_1546 a5ce6dd930c2465fe174dc2dc288fe52 340 PIRSF PIRSF000116 203 331 2.9E-14 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MCR_1546 a5ce6dd930c2465fe174dc2dc288fe52 340 PIRSF PIRSF000116 4 206 1.0E-48 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MCR_1546 a5ce6dd930c2465fe174dc2dc288fe52 340 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 3 330 45.076 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MCR_1546 a5ce6dd930c2465fe174dc2dc288fe52 340 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 3.5E-132 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 ProSitePatterns PS01175 Ribonuclease II family signature. 569 593 - T 14-10-2018 IPR022966 Ribonuclease II/R, conserved site MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 SMART SM00955 270 602 1.0E-167 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 97 728 1.6E-186 T 14-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 Hamap MF_01895 Ribonuclease R [rnr]. 50 728 50.302 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 SUPERFAMILY SSF50249 236 646 2.17E-136 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 SMART SM00316 646 728 2.2E-8 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 Gene3D G3DSA:2.40.50.140 649 769 2.0E-16 T 14-10-2018 MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 SMART SM00357 98 154 4.6E-10 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 Pfam PF00773 RNB domain 270 598 1.0E-109 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 SUPERFAMILY SSF50249 648 727 3.19E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 TIGRFAM TIGR02063 RNase_R: ribonuclease R 40 729 3.1E-223 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 Pfam PF08206 Ribonuclease B OB domain 99 153 1.3E-13 T 14-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 SUPERFAMILY SSF50249 147 248 1.14E-7 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 Gene3D G3DSA:2.40.50.140 69 157 2.4E-16 T 14-10-2018 MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 Pfam PF00575 S1 RNA binding domain 647 699 1.2E-9 T 14-10-2018 IPR003029 S1 domain GO:0003676 MCR_1455 eab9c78cef5a663ad7259f675ab088ac 770 SUPERFAMILY SSF50249 82 155 1.16E-13 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1149 226d3df34322d51b45a929d624a2496d 314 SUPERFAMILY SSF46785 12 126 4.82E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_1149 226d3df34322d51b45a929d624a2496d 314 Pfam PF03466 LysR substrate binding domain 103 311 5.5E-34 T 14-10-2018 IPR005119 LysR, substrate-binding MCR_1149 226d3df34322d51b45a929d624a2496d 314 Gene3D G3DSA:3.40.190.10 180 283 9.0E-73 T 14-10-2018 MCR_1149 226d3df34322d51b45a929d624a2496d 314 Gene3D G3DSA:1.10.10.10 8 98 1.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_1149 226d3df34322d51b45a929d624a2496d 314 Gene3D G3DSA:3.40.190.10 105 308 9.0E-73 T 14-10-2018 MCR_1149 226d3df34322d51b45a929d624a2496d 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 77 1.0E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1149 226d3df34322d51b45a929d624a2496d 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 53 1.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1149 226d3df34322d51b45a929d624a2496d 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 1.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1149 226d3df34322d51b45a929d624a2496d 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 1.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1149 226d3df34322d51b45a929d624a2496d 314 SUPERFAMILY SSF53850 105 313 1.34E-32 T 14-10-2018 MCR_1787 e65aba66ad04cee8b91c3c63c2e1371f 303 PIRSF PIRSF005303 1 303 8.1E-82 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MCR_1787 e65aba66ad04cee8b91c3c63c2e1371f 303 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 2 303 23.727 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MCR_1787 e65aba66ad04cee8b91c3c63c2e1371f 303 Gene3D G3DSA:3.90.650.10 125 303 1.6E-43 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MCR_1787 e65aba66ad04cee8b91c3c63c2e1371f 303 Gene3D G3DSA:3.30.1330.10 1 124 2.0E-38 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MCR_1787 e65aba66ad04cee8b91c3c63c2e1371f 303 SUPERFAMILY SSF56042 123 290 1.06E-31 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MCR_1787 e65aba66ad04cee8b91c3c63c2e1371f 303 Pfam PF00586 AIR synthase related protein, N-terminal domain 6 118 6.2E-23 T 14-10-2018 IPR016188 PurM-like, N-terminal domain MCR_1787 e65aba66ad04cee8b91c3c63c2e1371f 303 SUPERFAMILY SSF55326 2 118 6.13E-31 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MCR_1787 e65aba66ad04cee8b91c3c63c2e1371f 303 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 303 2.7E-89 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MCR_1208 ab0c49dad8f396cc76b8b4b14299e26a 327 Gene3D G3DSA:3.40.190.10 43 324 1.6E-76 T 14-10-2018 MCR_1208 ab0c49dad8f396cc76b8b4b14299e26a 327 Gene3D G3DSA:3.40.190.10 119 216 1.6E-76 T 14-10-2018 MCR_1208 ab0c49dad8f396cc76b8b4b14299e26a 327 SUPERFAMILY SSF53850 41 314 1.04E-37 T 14-10-2018 MCR_1208 ab0c49dad8f396cc76b8b4b14299e26a 327 Pfam PF09084 NMT1/THI5 like 48 255 1.4E-57 T 14-10-2018 IPR015168 SsuA/THI5-like MCR_1182 cbf84f7f06892badb1fe33c9f67789fc 344 SUPERFAMILY SSF50182 155 220 6.54E-16 T 14-10-2018 IPR010920 LSM domain superfamily MCR_1182 cbf84f7f06892badb1fe33c9f67789fc 344 Gene3D G3DSA:2.30.30.60 170 219 3.5E-15 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MCR_1182 cbf84f7f06892badb1fe33c9f67789fc 344 Gene3D G3DSA:3.30.70.100 222 313 1.9E-28 T 14-10-2018 MCR_1182 cbf84f7f06892badb1fe33c9f67789fc 344 Pfam PF00924 Mechanosensitive ion channel 113 309 6.9E-52 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MCR_1182 cbf84f7f06892badb1fe33c9f67789fc 344 Pfam PF05552 Conserved TM helix 59 105 7.1E-7 T 14-10-2018 IPR008910 Conserved TM helix MCR_1182 cbf84f7f06892badb1fe33c9f67789fc 344 SUPERFAMILY SSF82689 222 319 7.72E-33 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MCR_1182 cbf84f7f06892badb1fe33c9f67789fc 344 SUPERFAMILY SSF82861 71 152 7.85E-15 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MCR_0925 619931fadd3f2ae257cb53c563480cee 509 PIRSF PIRSF000485 1 485 1.0E-157 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MCR_0925 619931fadd3f2ae257cb53c563480cee 509 SUPERFAMILY SSF56235 2 259 2.74E-72 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MCR_0925 619931fadd3f2ae257cb53c563480cee 509 Pfam PF00156 Phosphoribosyl transferase domain 269 395 2.6E-8 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MCR_0925 619931fadd3f2ae257cb53c563480cee 509 Pfam PF13522 Glutamine amidotransferase domain 61 207 1.2E-17 T 14-10-2018 MCR_0925 619931fadd3f2ae257cb53c563480cee 509 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 468 2.8E-152 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MCR_0925 619931fadd3f2ae257cb53c563480cee 509 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 468 44.015 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MCR_0925 619931fadd3f2ae257cb53c563480cee 509 Gene3D G3DSA:3.40.50.2020 279 443 3.1E-149 T 14-10-2018 MCR_0925 619931fadd3f2ae257cb53c563480cee 509 Gene3D G3DSA:3.60.20.10 2 415 3.1E-149 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MCR_0925 619931fadd3f2ae257cb53c563480cee 509 SUPERFAMILY SSF53271 252 487 3.15E-71 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MCR_0240 93f1b2c2e2c264af8fd8f1a291e02870 236 Pfam PF01259 SAICAR synthetase 7 231 7.9E-63 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MCR_0240 93f1b2c2e2c264af8fd8f1a291e02870 236 SUPERFAMILY SSF56104 2 232 2.58E-77 T 14-10-2018 MCR_0240 93f1b2c2e2c264af8fd8f1a291e02870 236 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MCR_0240 93f1b2c2e2c264af8fd8f1a291e02870 236 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 5 233 3.2E-75 T 14-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 MCR_0240 93f1b2c2e2c264af8fd8f1a291e02870 236 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 234 30.466 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MCR_0240 93f1b2c2e2c264af8fd8f1a291e02870 236 Gene3D G3DSA:3.30.470.20 85 220 3.4E-90 T 14-10-2018 MCR_0240 93f1b2c2e2c264af8fd8f1a291e02870 236 Gene3D G3DSA:3.30.200.20 7 231 3.4E-90 T 14-10-2018 MCR_0130 c98747bf44d59969b58e3981c8fb10b1 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 6.1E-48 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0130 c98747bf44d59969b58e3981c8fb10b1 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0130 c98747bf44d59969b58e3981c8fb10b1 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.017 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0130 c98747bf44d59969b58e3981c8fb10b1 118 Gene3D G3DSA:1.10.1900.20 56 118 8.6E-27 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0130 c98747bf44d59969b58e3981c8fb10b1 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.7E-40 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0130 c98747bf44d59969b58e3981c8fb10b1 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.7E-40 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0130 c98747bf44d59969b58e3981c8fb10b1 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.7E-40 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0130 c98747bf44d59969b58e3981c8fb10b1 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 1.0E-12 T 14-10-2018 MCR_0130 c98747bf44d59969b58e3981c8fb10b1 118 Gene3D G3DSA:1.10.720.90 2 55 4.0E-23 T 14-10-2018 MCR_0130 c98747bf44d59969b58e3981c8fb10b1 118 Pfam PF00453 Ribosomal protein L20 3 109 3.8E-47 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0130 c98747bf44d59969b58e3981c8fb10b1 118 SUPERFAMILY SSF74731 3 117 3.14E-47 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0575 09b9300de4082b3e77a41b26850f76c6 254 Gene3D G3DSA:3.40.50.300 1 163 1.2E-23 T 14-10-2018 MCR_0575 09b9300de4082b3e77a41b26850f76c6 254 Pfam PF00308 Bacterial dnaA protein 41 209 2.5E-15 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA MCR_0575 09b9300de4082b3e77a41b26850f76c6 254 SUPERFAMILY SSF52540 29 213 1.5E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 Pfam PF01411 tRNA synthetases class II (A) 8 560 1.2E-224 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 870 0.0 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 SUPERFAMILY SSF55186 562 724 6.54E-46 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 Pfam PF02272 DHHA1 domain 746 888 7.4E-23 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 Gene3D G3DSA:2.40.30.130 471 558 9.0E-10 T 14-10-2018 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 SUPERFAMILY SSF50447 461 558 2.3E-17 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 Gene3D G3DSA:3.30.930.10 3 253 1.9E-123 T 14-10-2018 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 SMART SM00863 659 709 2.8E-21 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 Gene3D G3DSA:3.30.54.20 630 690 2.1E-46 T 14-10-2018 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 659 709 9.6E-17 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 PRINTS PR00980 Alanyl-tRNA synthetase signature 237 250 5.4E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 PRINTS PR00980 Alanyl-tRNA synthetase signature 210 221 5.4E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 PRINTS PR00980 Alanyl-tRNA synthetase signature 287 303 5.4E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 PRINTS PR00980 Alanyl-tRNA synthetase signature 77 88 5.4E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 PRINTS PR00980 Alanyl-tRNA synthetase signature 311 324 5.4E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 Gene3D G3DSA:3.30.980.10 568 710 2.1E-46 T 14-10-2018 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 SUPERFAMILY SSF55681 4 256 1.49E-107 T 14-10-2018 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 Gene3D G3DSA:3.10.310.40 777 889 4.5E-26 T 14-10-2018 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 892 188.977 T 14-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 MCR_0591 3a3205881d46056ce1a6cf9b62684df2 893 SUPERFAMILY SSF101353 257 470 2.62E-61 T 14-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 MCR_1480 d1089ff746475623e68134ab00e7d082 489 Gene3D G3DSA:3.40.50.10750 306 459 1.1E-130 T 14-10-2018 MCR_1480 d1089ff746475623e68134ab00e7d082 489 Gene3D G3DSA:3.40.50.10950 175 486 1.1E-130 T 14-10-2018 MCR_1480 d1089ff746475623e68134ab00e7d082 489 SUPERFAMILY SSF53659 169 486 3.95E-92 T 14-10-2018 MCR_1480 d1089ff746475623e68134ab00e7d082 489 Pfam PF01515 Phosphate acetyl/butaryl transferase 169 483 1.3E-121 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MCR_1480 d1089ff746475623e68134ab00e7d082 489 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 184 483 2.3E-125 T 14-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MCR_1855 7c8207428f3406cff50e1bceb465da24 196 Gene3D G3DSA:3.30.230.40 1 90 3.4E-37 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 MCR_1855 7c8207428f3406cff50e1bceb465da24 196 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MCR_1855 7c8207428f3406cff50e1bceb465da24 196 SUPERFAMILY SSF54211 3 87 1.16E-33 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1855 7c8207428f3406cff50e1bceb465da24 196 Gene3D G3DSA:3.30.230.40 91 196 2.3E-37 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 MCR_1855 7c8207428f3406cff50e1bceb465da24 196 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 175 2.5E-64 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MCR_1855 7c8207428f3406cff50e1bceb465da24 196 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 196 41.197 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MCR_1855 7c8207428f3406cff50e1bceb465da24 196 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 157 169 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MCR_1855 7c8207428f3406cff50e1bceb465da24 196 SUPERFAMILY SSF54211 88 180 2.02E-35 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 SUPERFAMILY SSF53706 222 769 1.95E-71 T 14-10-2018 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 82 3.9E-10 T 14-10-2018 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 Gene3D G3DSA:3.40.50.740 599 771 5.2E-7 T 14-10-2018 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 SMART SM00929 91 131 1.0E-18 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 224 277 8.3E-12 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 SUPERFAMILY SSF54292 1 80 1.57E-18 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 Gene3D G3DSA:3.10.20.740 1 131 4.8E-27 T 14-10-2018 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 SMART SM00926 224 278 1.1E-13 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 Gene3D G3DSA:2.20.25.90 224 278 2.1E-13 T 14-10-2018 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 91 129 2.7E-15 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 153 163 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 106 118 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 Gene3D G3DSA:3.40.50.740 283 489 6.8E-5 T 14-10-2018 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 548 1.5E-166 T 14-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0714 1d895a1e95823e6b47608d399705a6cc 1033 SUPERFAMILY SSF54862 84 216 7.11E-34 T 14-10-2018 MCR_1619 d503b77c184441f460222696e76f7109 1164 Hamap MF_00970 Ribonuclease E [rne]. 1 1137 28.11 T 14-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 MCR_1619 d503b77c184441f460222696e76f7109 1164 SUPERFAMILY SSF50249 40 122 2.62E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1619 d503b77c184441f460222696e76f7109 1164 Pfam PF00575 S1 RNA binding domain 36 114 4.5E-12 T 14-10-2018 IPR003029 S1 domain GO:0003676 MCR_1619 d503b77c184441f460222696e76f7109 1164 Gene3D G3DSA:2.40.50.140 31 122 4.5E-29 T 14-10-2018 MCR_1619 d503b77c184441f460222696e76f7109 1164 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 421 4.0E-156 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MCR_1619 d503b77c184441f460222696e76f7109 1164 Gene3D G3DSA:3.40.1260.20 398 503 6.0E-28 T 14-10-2018 MCR_1619 d503b77c184441f460222696e76f7109 1164 SMART SM00316 37 116 2.7E-9 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_1619 d503b77c184441f460222696e76f7109 1164 Pfam PF10150 Ribonuclease E/G family 118 387 4.0E-93 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MCR_0034 b44a5c8abb88e7f9ee9364381a7823a5 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 369 1.9E-10 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MCR_0034 b44a5c8abb88e7f9ee9364381a7823a5 460 Gene3D G3DSA:3.90.190.20 324 459 1.9E-28 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_0034 b44a5c8abb88e7f9ee9364381a7823a5 460 Gene3D G3DSA:3.40.1190.10 91 323 2.6E-57 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_0034 b44a5c8abb88e7f9ee9364381a7823a5 460 Pfam PF01225 Mur ligase family, catalytic domain 2 98 7.3E-16 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MCR_0034 b44a5c8abb88e7f9ee9364381a7823a5 460 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 457 2.8E-180 T 14-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 MCR_0034 b44a5c8abb88e7f9ee9364381a7823a5 460 Gene3D G3DSA:3.40.50.720 1 90 8.7E-33 T 14-10-2018 MCR_0034 b44a5c8abb88e7f9ee9364381a7823a5 460 SUPERFAMILY SSF53623 97 318 8.24E-47 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_0034 b44a5c8abb88e7f9ee9364381a7823a5 460 Pfam PF08245 Mur ligase middle domain 108 301 1.9E-26 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MCR_0034 b44a5c8abb88e7f9ee9364381a7823a5 460 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 458 53.865 T 14-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 MCR_0034 b44a5c8abb88e7f9ee9364381a7823a5 460 SUPERFAMILY SSF53244 320 457 2.62E-35 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_0034 b44a5c8abb88e7f9ee9364381a7823a5 460 SUPERFAMILY SSF51984 1 90 6.41E-22 T 14-10-2018 MCR_1139 379a692e70634c22316706635594e2ad 937 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 8 937 16.307 T 14-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 MCR_1139 379a692e70634c22316706635594e2ad 937 SUPERFAMILY SSF81301 508 801 1.01E-68 T 14-10-2018 MCR_1139 379a692e70634c22316706635594e2ad 937 Gene3D G3DSA:3.30.460.100 20 274 3.7E-58 T 14-10-2018 MCR_1139 379a692e70634c22316706635594e2ad 937 Gene3D G3DSA:3.30.460.100 545 797 3.4E-68 T 14-10-2018 MCR_1139 379a692e70634c22316706635594e2ad 937 SUPERFAMILY SSF81593 279 428 7.77E-37 T 14-10-2018 MCR_1139 379a692e70634c22316706635594e2ad 937 Gene3D G3DSA:1.20.120.330 798 937 1.3E-40 T 14-10-2018 MCR_1139 379a692e70634c22316706635594e2ad 937 SUPERFAMILY SSF81301 16 276 2.88E-57 T 14-10-2018 MCR_1139 379a692e70634c22316706635594e2ad 937 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 69 260 2.7E-59 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MCR_1139 379a692e70634c22316706635594e2ad 937 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 537 790 1.1E-64 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MCR_1139 379a692e70634c22316706635594e2ad 937 SUPERFAMILY SSF81593 803 936 3.3E-27 T 14-10-2018 MCR_1139 379a692e70634c22316706635594e2ad 937 Gene3D G3DSA:1.20.120.1510 433 544 4.9E-12 T 14-10-2018 MCR_1139 379a692e70634c22316706635594e2ad 937 Pfam PF08335 GlnD PII-uridylyltransferase 289 426 4.5E-36 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MCR_1139 379a692e70634c22316706635594e2ad 937 Pfam PF08335 GlnD PII-uridylyltransferase 813 912 8.7E-8 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MCR_1139 379a692e70634c22316706635594e2ad 937 Gene3D G3DSA:1.20.120.330 277 432 8.0E-45 T 14-10-2018 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 Gene3D G3DSA:3.30.499.10 694 876 1.2E-63 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 Gene3D G3DSA:3.20.19.10 165 366 2.8E-71 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 SUPERFAMILY SSF53732 384 866 5.23E-141 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 SUPERFAMILY SSF74778 4 163 3.27E-67 T 14-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 Pfam PF11791 Aconitate B N-terminal domain 7 159 4.8E-65 T 14-10-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 Pfam PF06434 Aconitate hydratase 2 N-terminus 171 387 4.9E-93 T 14-10-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 ProSitePatterns PS01244 Aconitase family signature 2. 773 786 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 SUPERFAMILY SSF52016 165 377 2.75E-65 T 14-10-2018 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 Pfam PF00330 Aconitase family (aconitate hydratase) 480 830 1.0E-37 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 Gene3D G3DSA:3.30.499.10 410 537 4.4E-143 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 4 865 0.0 T 14-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 ProSitePatterns PS00450 Aconitase family signature 1. 713 730 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 PIRSF PIRSF036687 2 871 0.0 T 14-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 Gene3D G3DSA:1.25.40.310 4 164 4.3E-67 T 14-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MCR_0394 7266e548d6e03eaf3563e7f39274eccf 877 Gene3D G3DSA:3.40.1060.10 390 692 4.4E-143 T 14-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MCR_0127 7083ac89ef1601f84a4fdda31e083e51 77 Pfam PF02416 mttA/Hcf106 family 4 52 3.2E-16 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MCR_0127 7083ac89ef1601f84a4fdda31e083e51 77 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 70 21.697 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MCR_0127 7083ac89ef1601f84a4fdda31e083e51 77 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 6.1E-22 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MCR_1709 8a5dfdbbec660b5b22c4865ddc4b4a93 83 SUPERFAMILY SSF54862 6 77 4.71E-19 T 14-10-2018 MCR_1709 8a5dfdbbec660b5b22c4865ddc4b4a93 83 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MCR_1709 8a5dfdbbec660b5b22c4865ddc4b4a93 83 Pfam PF00037 4Fe-4S binding domain 5 25 1.9E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MCR_1709 8a5dfdbbec660b5b22c4865ddc4b4a93 83 Gene3D G3DSA:3.30.70.20 2 81 1.6E-32 T 14-10-2018 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 355 435 5.1E-28 T 14-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 77 95 4.6E-9 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 7 27 4.6E-9 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 178 314 3.6E-22 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 144 5.8E-21 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 Gene3D G3DSA:3.40.50.300 174 352 3.5E-49 T 14-10-2018 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 Gene3D G3DSA:3.40.50.300 3 164 3.2E-40 T 14-10-2018 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 5 435 1.5E-174 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 SUPERFAMILY SSF52540 6 172 1.04E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 PIRSF PIRSF006485 3 443 6.0E-173 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 Hamap MF_00195 GTPase Der [der]. 4 438 38.397 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 Pfam PF01926 50S ribosome-binding GTPase 7 124 7.2E-26 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 Pfam PF01926 50S ribosome-binding GTPase 182 299 3.7E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 SUPERFAMILY SSF52540 141 441 6.9E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1166 0506fa70799df741eb18ffcccbbd2d36 472 Gene3D G3DSA:3.30.300.20 355 437 6.2E-23 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MCR_0727 fbe1e9f2307f01efef7fd1bfe55b47a8 332 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 200 325 4.9E-26 T 14-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0727 fbe1e9f2307f01efef7fd1bfe55b47a8 332 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 332 58.226 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0727 fbe1e9f2307f01efef7fd1bfe55b47a8 332 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 25 321 6.6E-55 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0727 fbe1e9f2307f01efef7fd1bfe55b47a8 332 SUPERFAMILY SSF56194 196 328 6.54E-37 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0727 fbe1e9f2307f01efef7fd1bfe55b47a8 332 Gene3D G3DSA:3.30.465.10 57 212 1.2E-52 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MCR_0727 fbe1e9f2307f01efef7fd1bfe55b47a8 332 Pfam PF01565 FAD binding domain 25 125 2.7E-15 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MCR_0727 fbe1e9f2307f01efef7fd1bfe55b47a8 332 Gene3D G3DSA:3.90.78.10 213 331 9.2E-33 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0727 fbe1e9f2307f01efef7fd1bfe55b47a8 332 SUPERFAMILY SSF56176 24 173 8.72E-33 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 Pfam PF00009 Elongation factor Tu GTP binding domain 11 215 1.6E-36 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 61 76 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 SUPERFAMILY SSF50447 231 317 2.5E-16 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 PRINTS PR00315 GTP-binding elongation factor signature 88 98 5.8E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 PRINTS PR00315 GTP-binding elongation factor signature 11 24 5.8E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 PRINTS PR00315 GTP-binding elongation factor signature 104 115 5.8E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 PRINTS PR00315 GTP-binding elongation factor signature 68 76 5.8E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 PRINTS PR00315 GTP-binding elongation factor signature 149 158 5.8E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 Gene3D G3DSA:3.40.50.300 2 225 1.0E-62 T 14-10-2018 MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 SUPERFAMILY SSF52540 7 219 1.92E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 10 426 1.4E-151 T 14-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 Gene3D G3DSA:2.40.30.10 229 319 7.7E-21 T 14-10-2018 MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 Gene3D G3DSA:2.40.30.10 324 428 1.1E-32 T 14-10-2018 MCR_0097 a87dc8fd2ff244fca949dd3c2eac6f81 434 SUPERFAMILY SSF50465 325 427 2.93E-30 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MCR_1874 012ec76dba820293a7418f188fa1bec8 411 Gene3D G3DSA:3.30.420.40 33 407 1.6E-120 T 14-10-2018 MCR_1874 012ec76dba820293a7418f188fa1bec8 411 SUPERFAMILY SSF53067 27 364 3.58E-21 T 14-10-2018 MCR_1874 012ec76dba820293a7418f188fa1bec8 411 Gene3D G3DSA:3.30.420.40 183 372 1.6E-120 T 14-10-2018 MCR_1874 012ec76dba820293a7418f188fa1bec8 411 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 26 411 37.849 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 MCR_1874 012ec76dba820293a7418f188fa1bec8 411 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 27 409 1.3E-129 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 MCR_0626 3f211edec55424e658ad30e84222d186 881 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 278 876 3.9E-137 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MCR_0626 3f211edec55424e658ad30e84222d186 881 SUPERFAMILY SSF81653 387 474 8.76E-15 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MCR_0626 3f211edec55424e658ad30e84222d186 881 Pfam PF00403 Heavy-metal-associated domain 127 187 1.3E-7 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MCR_0626 3f211edec55424e658ad30e84222d186 881 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 356 858 1.8E-68 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MCR_0626 3f211edec55424e658ad30e84222d186 881 Gene3D G3DSA:3.40.50.1000 567 824 6.5E-68 T 14-10-2018 IPR023214 HAD superfamily MCR_0626 3f211edec55424e658ad30e84222d186 881 SUPERFAMILY SSF81665 476 567 1.01E-12 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MCR_0626 3f211edec55424e658ad30e84222d186 881 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 41 119 7.6E-17 T 14-10-2018 IPR021993 Putative metal-binding domain of cation transport ATPase MCR_0626 3f211edec55424e658ad30e84222d186 881 ProSitePatterns PS01047 Heavy-metal-associated domain. 129 158 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MCR_0626 3f211edec55424e658ad30e84222d186 881 SUPERFAMILY SSF56784 572 875 7.71E-47 T 14-10-2018 IPR036412 HAD-like superfamily MCR_0626 3f211edec55424e658ad30e84222d186 881 Gene3D G3DSA:3.30.70.100 118 190 2.8E-15 T 14-10-2018 MCR_0626 3f211edec55424e658ad30e84222d186 881 Pfam PF00122 E1-E2 ATPase 389 551 6.8E-42 T 14-10-2018 MCR_0626 3f211edec55424e658ad30e84222d186 881 Gene3D G3DSA:3.40.1110.10 584 707 6.5E-68 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MCR_0626 3f211edec55424e658ad30e84222d186 881 Gene3D G3DSA:2.70.150.20 366 479 7.6E-17 T 14-10-2018 MCR_0626 3f211edec55424e658ad30e84222d186 881 SUPERFAMILY SSF55008 117 195 2.36E-18 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MCR_0626 3f211edec55424e658ad30e84222d186 881 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 575 581 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MCR_0626 3f211edec55424e658ad30e84222d186 881 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 722 732 9.0E-18 T 14-10-2018 MCR_0626 3f211edec55424e658ad30e84222d186 881 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 798 810 9.0E-18 T 14-10-2018 MCR_0626 3f211edec55424e658ad30e84222d186 881 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 425 439 9.0E-18 T 14-10-2018 MCR_0626 3f211edec55424e658ad30e84222d186 881 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 775 794 9.0E-18 T 14-10-2018 MCR_0626 3f211edec55424e658ad30e84222d186 881 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 573 587 9.0E-18 T 14-10-2018 MCR_0626 3f211edec55424e658ad30e84222d186 881 SUPERFAMILY SSF81660 575 682 7.85E-15 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MCR_0626 3f211edec55424e658ad30e84222d186 881 Pfam PF00702 haloacid dehalogenase-like hydrolase 571 789 8.7E-34 T 14-10-2018 MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 SUPERFAMILY SSF68912 1 46 4.32E-12 T 14-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 SUPERFAMILY SSF50249 49 125 3.43E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 Gene3D G3DSA:1.10.720.10 1 46 6.7E-21 T 14-10-2018 MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 1.3E-16 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 SUPERFAMILY SSF52540 90 370 1.62E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 Gene3D G3DSA:2.40.50.140 47 123 2.8E-33 T 14-10-2018 MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 1.6E-24 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 9.3E-208 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 SMART SM00357 52 118 2.1E-17 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 5.4E-31 T 14-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 Gene3D G3DSA:3.40.50.300 130 417 9.5E-130 T 14-10-2018 MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 420 237.608 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 SMART SM00382 170 355 3.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1741 49d3caf27e20f9276a96e86ae095ecee 422 SMART SM00959 5 47 7.1E-18 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MCR_1845 04a7dc5795edc6c348eaeeab2b98e863 410 SUPERFAMILY SSF103473 19 408 1.7E-36 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_1845 04a7dc5795edc6c348eaeeab2b98e863 410 Pfam PF07690 Major Facilitator Superfamily 25 313 4.8E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MCR_1845 04a7dc5795edc6c348eaeeab2b98e863 410 Gene3D G3DSA:1.20.1250.20 2 408 2.8E-31 T 14-10-2018 MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 Pfam PF10415 Fumarase C C-terminus 407 459 1.3E-23 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 461 90.287 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 PRINTS PR00145 Argininosuccinate lyase family signature 174 194 4.1E-6 T 14-10-2018 MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 PRINTS PR00145 Argininosuccinate lyase family signature 132 154 4.1E-6 T 14-10-2018 MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 PRINTS PR00145 Argininosuccinate lyase family signature 316 332 4.1E-6 T 14-10-2018 MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 1.4E-33 T 14-10-2018 IPR000362 Fumarate lyase family MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 PRINTS PR00149 Fumarate lyase superfamily signature 316 332 1.4E-33 T 14-10-2018 IPR000362 Fumarate lyase family MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 1.4E-33 T 14-10-2018 IPR000362 Fumarate lyase family MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 PRINTS PR00149 Fumarate lyase superfamily signature 270 297 1.4E-33 T 14-10-2018 IPR000362 Fumarate lyase family MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 Gene3D G3DSA:1.10.275.10 4 137 4.4E-61 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 Pfam PF00206 Lyase 11 341 5.8E-116 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 SUPERFAMILY SSF48557 3 459 4.86E-160 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 Gene3D G3DSA:1.20.200.10 138 404 3.8E-114 T 14-10-2018 MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 4 460 2.5E-230 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 ProSitePatterns PS00163 Fumarate lyases signature. 316 325 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MCR_1072 0f03817d501b50d0adfae9fcbd031141 462 Gene3D G3DSA:1.10.40.30 405 462 9.9E-26 T 14-10-2018 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00691 Adhesin B signature 38 59 2.7E-41 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00691 Adhesin B signature 285 303 2.7E-41 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00691 Adhesin B signature 264 282 2.7E-41 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00691 Adhesin B signature 63 81 2.7E-41 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00691 Adhesin B signature 82 101 2.7E-41 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00691 Adhesin B signature 193 210 2.7E-41 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00691 Adhesin B signature 219 237 2.7E-41 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00691 Adhesin B signature 242 259 2.7E-41 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 Gene3D G3DSA:3.40.50.1980 195 308 3.4E-43 T 14-10-2018 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 SUPERFAMILY SSF53807 35 306 7.85E-94 T 14-10-2018 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00690 Adhesin family signature 69 82 1.7E-47 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00690 Adhesin family signature 82 99 1.7E-47 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00690 Adhesin family signature 246 264 1.7E-47 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00690 Adhesin family signature 193 214 1.7E-47 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00690 Adhesin family signature 38 56 1.7E-47 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 PRINTS PR00690 Adhesin family signature 272 291 1.7E-47 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 Gene3D G3DSA:3.40.50.1980 37 194 2.1E-55 T 14-10-2018 MCR_1867 5a20d444c4d93065617bb5c18309f8ea 308 Pfam PF01297 Zinc-uptake complex component A periplasmic 41 304 2.2E-79 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MCR_0089 839200f57a23a6f606d694c22f67bf48 438 Gene3D G3DSA:3.40.50.300 79 338 6.2E-109 T 14-10-2018 MCR_0089 839200f57a23a6f606d694c22f67bf48 438 Gene3D G3DSA:1.10.8.60 339 438 2.6E-37 T 14-10-2018 MCR_0089 839200f57a23a6f606d694c22f67bf48 438 SUPERFAMILY SSF57716 8 42 3.85E-9 T 14-10-2018 MCR_0089 839200f57a23a6f606d694c22f67bf48 438 SUPERFAMILY SSF52540 84 424 8.01E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0089 839200f57a23a6f606d694c22f67bf48 438 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 340 418 3.9E-17 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MCR_0089 839200f57a23a6f606d694c22f67bf48 438 SMART SM00382 136 289 1.0E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0089 839200f57a23a6f606d694c22f67bf48 438 SMART SM00994 6 45 1.7E-16 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MCR_0089 839200f57a23a6f606d694c22f67bf48 438 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 5 431 1.7E-201 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MCR_0089 839200f57a23a6f606d694c22f67bf48 438 Gene3D G3DSA:3.30.50.30 2 44 1.4E-14 T 14-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily MCR_0089 839200f57a23a6f606d694c22f67bf48 438 SMART SM01086 340 433 3.3E-34 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MCR_0089 839200f57a23a6f606d694c22f67bf48 438 Pfam PF07724 AAA domain (Cdc48 subfamily) 137 333 1.1E-49 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MCR_0089 839200f57a23a6f606d694c22f67bf48 438 Pfam PF06689 ClpX C4-type zinc finger 8 42 6.0E-15 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MCR_0089 839200f57a23a6f606d694c22f67bf48 438 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 438 51.969 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MCR_0304 b7dd45bebed6fb269e1f6c823639d68b 64 Pfam PF08282 haloacid dehalogenase-like hydrolase 12 58 4.5E-9 T 14-10-2018 MCR_0304 b7dd45bebed6fb269e1f6c823639d68b 64 Gene3D G3DSA:3.40.50.1000 10 56 2.7E-11 T 14-10-2018 IPR023214 HAD superfamily MCR_0304 b7dd45bebed6fb269e1f6c823639d68b 64 SUPERFAMILY SSF56784 9 58 2.61E-12 T 14-10-2018 IPR036412 HAD-like superfamily MCR_1126 198940077af506bb38128a183ee45157 410 Gene3D G3DSA:3.40.50.880 165 409 5.0E-70 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_1126 198940077af506bb38128a183ee45157 410 PRINTS PR00097 Anthranilate synthase component II signature 380 393 2.6E-5 T 14-10-2018 MCR_1126 198940077af506bb38128a183ee45157 410 PRINTS PR00097 Anthranilate synthase component II signature 266 275 2.6E-5 T 14-10-2018 MCR_1126 198940077af506bb38128a183ee45157 410 PRINTS PR00097 Anthranilate synthase component II signature 295 306 2.6E-5 T 14-10-2018 MCR_1126 198940077af506bb38128a183ee45157 410 PRINTS PR00096 Glutamine amidotransferase superfamily signature 295 306 3.9E-10 T 14-10-2018 MCR_1126 198940077af506bb38128a183ee45157 410 PRINTS PR00096 Glutamine amidotransferase superfamily signature 380 393 3.9E-10 T 14-10-2018 MCR_1126 198940077af506bb38128a183ee45157 410 PRINTS PR00096 Glutamine amidotransferase superfamily signature 266 275 3.9E-10 T 14-10-2018 MCR_1126 198940077af506bb38128a183ee45157 410 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 9 407 4.3E-136 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1126 198940077af506bb38128a183ee45157 410 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 7 409 45.126 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1126 198940077af506bb38128a183ee45157 410 SUPERFAMILY SSF52021 7 148 6.8E-53 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1126 198940077af506bb38128a183ee45157 410 Gene3D G3DSA:3.50.30.20 6 158 1.4E-53 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1126 198940077af506bb38128a183ee45157 410 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 8 139 1.9E-48 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1126 198940077af506bb38128a183ee45157 410 SMART SM01097 7 140 4.1E-83 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1126 198940077af506bb38128a183ee45157 410 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 337 348 4.6E-37 T 14-10-2018 MCR_1126 198940077af506bb38128a183ee45157 410 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 295 311 4.6E-37 T 14-10-2018 MCR_1126 198940077af506bb38128a183ee45157 410 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 224 238 4.6E-37 T 14-10-2018 MCR_1126 198940077af506bb38128a183ee45157 410 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 263 277 4.6E-37 T 14-10-2018 MCR_1126 198940077af506bb38128a183ee45157 410 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 312 329 4.6E-37 T 14-10-2018 MCR_1126 198940077af506bb38128a183ee45157 410 SUPERFAMILY SSF52317 212 406 2.06E-58 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_1126 198940077af506bb38128a183ee45157 410 Pfam PF00117 Glutamine amidotransferase class-I 227 402 7.3E-45 T 14-10-2018 IPR017926 Glutamine amidotransferase MCR_1098 d39887dde7240073617ceafedccdfc98 621 SUPERFAMILY SSF52540 366 611 1.74E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1098 d39887dde7240073617ceafedccdfc98 621 SMART SM00382 403 589 1.0E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1098 d39887dde7240073617ceafedccdfc98 621 Gene3D G3DSA:3.40.50.300 364 616 1.1E-85 T 14-10-2018 MCR_1098 d39887dde7240073617ceafedccdfc98 621 SUPERFAMILY SSF90123 21 362 1.15E-57 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MCR_1098 d39887dde7240073617ceafedccdfc98 621 Gene3D G3DSA:1.20.1560.10 9 363 3.4E-59 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MCR_1098 d39887dde7240073617ceafedccdfc98 621 Pfam PF00005 ABC transporter 394 543 7.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1098 d39887dde7240073617ceafedccdfc98 621 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 17 614 3.9E-238 T 14-10-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 MCR_1098 d39887dde7240073617ceafedccdfc98 621 ProSitePatterns PS00211 ABC transporters family signature. 515 529 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1098 d39887dde7240073617ceafedccdfc98 621 Pfam PF00664 ABC transporter transmembrane region 78 332 7.5E-39 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MCR_0474 6886990bc288bf16f5f5789e787cd46d 473 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 333 2.0E-12 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MCR_0474 6886990bc288bf16f5f5789e787cd46d 473 SUPERFAMILY SSF111369 55 132 9.29E-17 T 14-10-2018 MCR_0474 6886990bc288bf16f5f5789e787cd46d 473 Gene3D G3DSA:2.40.50.100 65 249 2.9E-66 T 14-10-2018 MCR_0474 6886990bc288bf16f5f5789e787cd46d 473 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 180 415 8.4E-44 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MCR_0474 6886990bc288bf16f5f5789e787cd46d 473 Gene3D G3DSA:1.10.287.470 124 207 2.9E-66 T 14-10-2018 MCR_0474 6886990bc288bf16f5f5789e787cd46d 473 Gene3D G3DSA:2.40.420.20 41 400 2.9E-66 T 14-10-2018 MCR_0474 6886990bc288bf16f5f5789e787cd46d 473 Gene3D G3DSA:2.40.30.170 53 340 2.9E-66 T 14-10-2018 MCR_0474 6886990bc288bf16f5f5789e787cd46d 473 SUPERFAMILY SSF111369 127 338 1.16E-44 T 14-10-2018 MCR_1153 7f99e632fbd00331edef3f99b14ab8c8 247 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 95 151 4.0E-13 T 14-10-2018 MCR_1153 7f99e632fbd00331edef3f99b14ab8c8 247 Hamap MF_00013 Octanoyltransferase [lipB]. 19 241 30.642 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MCR_1153 7f99e632fbd00331edef3f99b14ab8c8 247 SUPERFAMILY SSF55681 19 229 2.29E-45 T 14-10-2018 MCR_1153 7f99e632fbd00331edef3f99b14ab8c8 247 PIRSF PIRSF016262 15 245 9.9E-56 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MCR_1153 7f99e632fbd00331edef3f99b14ab8c8 247 Gene3D G3DSA:3.30.930.10 15 230 2.3E-48 T 14-10-2018 MCR_1153 7f99e632fbd00331edef3f99b14ab8c8 247 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 48 231 2.3E-48 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MCR_1153 7f99e632fbd00331edef3f99b14ab8c8 247 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 91 106 - T 14-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MCR_1095 46c89a9160310f008cec628401b80720 317 Gene3D G3DSA:3.40.50.2000 2 291 3.7E-51 T 14-10-2018 MCR_1095 46c89a9160310f008cec628401b80720 317 Pfam PF00534 Glycosyl transferases group 1 177 259 9.3E-11 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MCR_1095 46c89a9160310f008cec628401b80720 317 Gene3D G3DSA:3.40.50.2000 114 285 3.7E-51 T 14-10-2018 MCR_1095 46c89a9160310f008cec628401b80720 317 SUPERFAMILY SSF53756 3 293 1.75E-36 T 14-10-2018 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Pfam PF06827 Zinc finger found in FPG and IleRS 1058 1084 2.5E-6 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 SUPERFAMILY SSF50677 208 280 1.27E-11 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 55 66 1.4E-13 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 239 262 1.4E-13 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 32 269 1.5E-83 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 440 814 1.5E-118 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Gene3D G3DSA:3.40.50.620 538 811 2.4E-72 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Gene3D G3DSA:3.40.50.620 19 217 1.4E-57 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 SUPERFAMILY SSF52374 7 821 4.73E-134 T 14-10-2018 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Pfam PF13302 Acetyltransferase (GNAT) domain 284 414 5.7E-15 T 14-10-2018 IPR000182 GNAT domain MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 SUPERFAMILY SSF55729 278 419 4.66E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Gene3D G3DSA:3.90.740.10 228 301 9.1E-9 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Gene3D G3DSA:3.40.630.30 322 413 2.0E-8 T 14-10-2018 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 SUPERFAMILY SSF47323 826 1087 3.92E-72 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Gene3D G3DSA:3.90.740.10 414 537 6.3E-17 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Pfam PF08264 Anticodon-binding domain of tRNA 859 1013 5.5E-28 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 62 73 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 SUPERFAMILY SSF50677 435 576 3.27E-34 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Gene3D G3DSA:1.10.730.20 814 1088 4.9E-85 T 14-10-2018 MCR_0500 f4cb0c5ee0643ebd743ca8d05ae300cd 1095 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 6 1087 20.501 T 14-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 MCR_1047 1ef7cc477674d799cb707f0936423a9b 112 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 29 107 4.3E-27 T 14-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 MCR_1047 1ef7cc477674d799cb707f0936423a9b 112 SUPERFAMILY SSF54736 27 111 1.73E-26 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MCR_1047 1ef7cc477674d799cb707f0936423a9b 112 Gene3D G3DSA:3.30.1390.10 9 112 6.0E-34 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MCR_1047 1ef7cc477674d799cb707f0936423a9b 112 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 14 107 22.179 T 14-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS MCR_0294 91b50c39c10ed9da5835a7b720970a26 535 Gene3D G3DSA:1.10.3720.10 283 534 1.4E-25 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0294 91b50c39c10ed9da5835a7b720970a26 535 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 252 2.6E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_0294 91b50c39c10ed9da5835a7b720970a26 535 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 344 529 6.6E-6 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_0294 91b50c39c10ed9da5835a7b720970a26 535 SUPERFAMILY SSF161098 9 257 4.97E-39 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0294 91b50c39c10ed9da5835a7b720970a26 535 Gene3D G3DSA:1.10.3720.10 9 266 1.1E-46 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0294 91b50c39c10ed9da5835a7b720970a26 535 SUPERFAMILY SSF161098 281 531 1.96E-33 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1577 a1e1d2ae4795dcc2e47b221626f71441 65 Pfam PF00831 Ribosomal L29 protein 4 60 9.2E-20 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1577 a1e1d2ae4795dcc2e47b221626f71441 65 Gene3D G3DSA:1.10.287.310 1 65 9.4E-22 T 14-10-2018 MCR_1577 a1e1d2ae4795dcc2e47b221626f71441 65 SUPERFAMILY SSF46561 1 63 2.22E-19 T 14-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1577 a1e1d2ae4795dcc2e47b221626f71441 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 16.76 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1577 a1e1d2ae4795dcc2e47b221626f71441 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 2.2E-19 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 Gene3D G3DSA:3.40.50.720 215 378 7.1E-69 T 14-10-2018 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 SUPERFAMILY SSF52283 13 469 4.48E-106 T 14-10-2018 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 208 381 3.7E-58 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 230 246 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 15 158 8.0E-71 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 Gene3D G3DSA:3.40.50.1480 379 469 1.1E-30 T 14-10-2018 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 SMART SM00997 208 381 6.7E-82 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 PIRSF PIRSF001109 3 469 3.3E-178 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 SUPERFAMILY SSF51735 208 381 5.71E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 11 461 44.089 T 14-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 16 461 2.9E-155 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 Gene3D G3DSA:3.40.50.1480 13 214 3.7E-90 T 14-10-2018 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 87 101 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MCR_0687 97ee5906e2bb6ec4a238e5820f50a8a6 469 SMART SM00996 15 468 8.4E-273 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MCR_1156 167a835e4c58f03eb566e6c7fe63d5ff 162 SUPERFAMILY SSF103642 140 161 2.62E-7 T 14-10-2018 MCR_1156 167a835e4c58f03eb566e6c7fe63d5ff 162 SUPERFAMILY SSF54427 28 136 3.94E-31 T 14-10-2018 IPR032710 NTF2-like domain superfamily MCR_1156 167a835e4c58f03eb566e6c7fe63d5ff 162 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 4 135 26.031 T 14-10-2018 IPR023006 Uncharacterised protein family UPF0225 MCR_1156 167a835e4c58f03eb566e6c7fe63d5ff 162 Pfam PF02810 SEC-C motif 144 160 9.6E-6 T 14-10-2018 IPR004027 SEC-C motif MCR_1156 167a835e4c58f03eb566e6c7fe63d5ff 162 Gene3D G3DSA:3.10.450.50 2 162 1.2E-49 T 14-10-2018 MCR_0247 95655e9af7e55dcc6625e3a184496e5a 310 Gene3D G3DSA:1.10.8.60 208 291 3.4E-7 T 14-10-2018 MCR_0247 95655e9af7e55dcc6625e3a184496e5a 310 Gene3D G3DSA:3.40.50.300 27 207 1.1E-34 T 14-10-2018 MCR_0247 95655e9af7e55dcc6625e3a184496e5a 310 SMART SM00382 75 208 1.0E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0247 95655e9af7e55dcc6625e3a184496e5a 310 SUPERFAMILY SSF52540 47 273 1.34E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0247 95655e9af7e55dcc6625e3a184496e5a 310 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 81 204 5.5E-28 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MCR_1446 1aeecdb9e0bb142c36635cda74a47e95 328 SUPERFAMILY SSF51735 3 157 4.88E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1446 1aeecdb9e0bb142c36635cda74a47e95 328 PIRSF PIRSF000102 1 326 8.9E-66 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MCR_1446 1aeecdb9e0bb142c36635cda74a47e95 328 SUPERFAMILY SSF56327 159 326 9.88E-59 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MCR_1446 1aeecdb9e0bb142c36635cda74a47e95 328 Gene3D G3DSA:3.40.50.720 1 156 1.1E-59 T 14-10-2018 MCR_1446 1aeecdb9e0bb142c36635cda74a47e95 328 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 159 320 6.6E-33 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MCR_1446 1aeecdb9e0bb142c36635cda74a47e95 328 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 154 2.3E-37 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MCR_1446 1aeecdb9e0bb142c36635cda74a47e95 328 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 2 321 6.5E-147 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MCR_1446 1aeecdb9e0bb142c36635cda74a47e95 328 Hamap MF_01517 Malate dehydrogenase [mdh]. 1 327 56.523 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MCR_1446 1aeecdb9e0bb142c36635cda74a47e95 328 Gene3D G3DSA:3.90.110.10 157 328 1.6E-61 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MCR_0670 3b63e0c4cf5fe35e8cf3284f3e1181cd 508 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 11 505 3.2E-232 T 14-10-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 MCR_0670 3b63e0c4cf5fe35e8cf3284f3e1181cd 508 Gene3D G3DSA:3.40.1080.20 342 482 6.0E-40 T 14-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily MCR_0670 3b63e0c4cf5fe35e8cf3284f3e1181cd 508 SUPERFAMILY SSF100950 232 506 5.44E-76 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MCR_0670 3b63e0c4cf5fe35e8cf3284f3e1181cd 508 Gene3D G3DSA:3.40.1080.10 8 177 2.8E-16 T 14-10-2018 MCR_0670 3b63e0c4cf5fe35e8cf3284f3e1181cd 508 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 11 221 2.0E-32 T 14-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 MCR_0670 3b63e0c4cf5fe35e8cf3284f3e1181cd 508 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 326 469 7.7E-42 T 14-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain MCR_0670 3b63e0c4cf5fe35e8cf3284f3e1181cd 508 SUPERFAMILY SSF100950 4 228 1.08E-62 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MCR_1018 261564a91ade06e14b603aaae476ccdd 507 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 17 506 7.7E-198 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_1018 261564a91ade06e14b603aaae476ccdd 507 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 22 507 43.431 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_1018 261564a91ade06e14b603aaae476ccdd 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 217 233 1.1E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_1018 261564a91ade06e14b603aaae476ccdd 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 264 281 1.1E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_1018 261564a91ade06e14b603aaae476ccdd 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 201 211 1.1E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_1018 261564a91ade06e14b603aaae476ccdd 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 246 259 1.1E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_1018 261564a91ade06e14b603aaae476ccdd 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 389 405 1.1E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_1018 261564a91ade06e14b603aaae476ccdd 507 Gene3D G3DSA:3.30.930.10 159 504 1.2E-128 T 14-10-2018 MCR_1018 261564a91ade06e14b603aaae476ccdd 507 Pfam PF01336 OB-fold nucleic acid binding domain 76 148 3.2E-9 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MCR_1018 261564a91ade06e14b603aaae476ccdd 507 Gene3D G3DSA:2.40.50.140 8 158 4.3E-31 T 14-10-2018 MCR_1018 261564a91ade06e14b603aaae476ccdd 507 SUPERFAMILY SSF55681 164 505 2.19E-117 T 14-10-2018 MCR_1018 261564a91ade06e14b603aaae476ccdd 507 SUPERFAMILY SSF50249 15 157 1.91E-29 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1018 261564a91ade06e14b603aaae476ccdd 507 Pfam PF00152 tRNA synthetases class II (D, K and N) 165 504 1.1E-80 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0109 3dff7c5189346ddc58d5fcef6d302a78 554 Gene3D G3DSA:3.30.450.90 141 272 2.4E-47 T 14-10-2018 MCR_0109 3dff7c5189346ddc58d5fcef6d302a78 554 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 8 548 1.2E-203 T 14-10-2018 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 MCR_0109 3dff7c5189346ddc58d5fcef6d302a78 554 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 41 143 3.0E-11 T 14-10-2018 IPR007831 General secretory system II, protein E, N-terminal MCR_0109 3dff7c5189346ddc58d5fcef6d302a78 554 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 367 381 - T 14-10-2018 IPR001482 Type II/IV secretion system protein MCR_0109 3dff7c5189346ddc58d5fcef6d302a78 554 Pfam PF00437 Type II/IV secretion system protein 174 439 2.3E-86 T 14-10-2018 IPR001482 Type II/IV secretion system protein MCR_0109 3dff7c5189346ddc58d5fcef6d302a78 554 SUPERFAMILY SSF52540 159 547 1.94E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0109 3dff7c5189346ddc58d5fcef6d302a78 554 SUPERFAMILY SSF160246 4 141 7.32E-23 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily MCR_0109 3dff7c5189346ddc58d5fcef6d302a78 554 Gene3D G3DSA:3.30.300.160 63 140 1.1E-8 T 14-10-2018 MCR_0109 3dff7c5189346ddc58d5fcef6d302a78 554 Gene3D G3DSA:3.40.50.300 275 550 3.2E-103 T 14-10-2018 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 Gene3D G3DSA:3.40.50.300 22 415 8.6E-170 T 14-10-2018 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 817 0.0 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 SUPERFAMILY SSF81886 620 919 5.36E-75 T 14-10-2018 IPR036266 SecA, Wing/Scaffold superfamily MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 Gene3D G3DSA:1.10.3060.10 621 832 3.7E-70 T 14-10-2018 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 SMART SM00957 6 402 2.0E-286 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 Pfam PF07517 SecA DEAD-like domain 7 402 4.0E-130 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 SUPERFAMILY SSF81767 227 368 6.67E-40 T 14-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 ProSitePatterns PS01312 SecA family signature. 500 515 - T 14-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 832 19.526 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 Gene3D G3DSA:3.40.50.300 417 620 3.1E-83 T 14-10-2018 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 SUPERFAMILY SSF52540 416 618 2.66E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 Pfam PF07516 SecA Wing and Scaffold domain 617 829 9.0E-63 T 14-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 Gene3D G3DSA:3.90.1440.10 229 368 8.6E-170 T 14-10-2018 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 SUPERFAMILY SSF52540 6 415 7.45E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 Pfam PF01043 SecA preprotein cross-linking domain 233 358 6.1E-34 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 Gene3D G3DSA:3.10.450.50 889 930 9.5E-7 T 14-10-2018 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 PRINTS PR00906 SecA protein signature 413 426 4.5E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 PRINTS PR00906 SecA protein signature 101 115 4.5E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 PRINTS PR00906 SecA protein signature 376 393 4.5E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 PRINTS PR00906 SecA protein signature 170 190 4.5E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 PRINTS PR00906 SecA protein signature 339 361 4.5E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 PRINTS PR00906 SecA protein signature 63 87 4.5E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 PRINTS PR00906 SecA protein signature 117 127 4.5E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 SMART SM00958 228 358 1.9E-66 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MCR_0213 f8db70ab4765cb7ce72a45eea5605093 931 Pfam PF02810 SEC-C motif 911 929 6.7E-10 T 14-10-2018 IPR004027 SEC-C motif MCR_1437 b589e0ec7a620b510ead0acd6d990278 372 PIRSF PIRSF001455 8 366 2.0E-107 T 14-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MCR_1437 b589e0ec7a620b510ead0acd6d990278 372 SUPERFAMILY SSF56796 14 359 2.75E-112 T 14-10-2018 MCR_1437 b589e0ec7a620b510ead0acd6d990278 372 Gene3D G3DSA:3.40.50.1970 2 176 3.3E-60 T 14-10-2018 MCR_1437 b589e0ec7a620b510ead0acd6d990278 372 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 29 351 1.0E-119 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MCR_1437 b589e0ec7a620b510ead0acd6d990278 372 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 359 66.972 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MCR_1437 b589e0ec7a620b510ead0acd6d990278 372 Gene3D G3DSA:1.20.1090.10 177 364 1.4E-69 T 14-10-2018 MCR_1437 b589e0ec7a620b510ead0acd6d990278 372 Pfam PF01761 3-dehydroquinate synthase 71 328 1.2E-108 T 14-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MCR_1262 2505d1e01c4ce994d39876f1b57d218a 689 Gene3D G3DSA:3.40.50.300 293 653 1.8E-115 T 14-10-2018 MCR_1262 2505d1e01c4ce994d39876f1b57d218a 689 Pfam PF00580 UvrD/REP helicase N-terminal domain 19 284 1.6E-74 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MCR_1262 2505d1e01c4ce994d39876f1b57d218a 689 SUPERFAMILY SSF52540 12 659 2.8E-160 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1262 2505d1e01c4ce994d39876f1b57d218a 689 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 17 685 36.943 T 14-10-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 MCR_1262 2505d1e01c4ce994d39876f1b57d218a 689 Gene3D G3DSA:3.40.50.300 20 285 1.8E-92 T 14-10-2018 MCR_1262 2505d1e01c4ce994d39876f1b57d218a 689 Pfam PF13361 UvrD-like helicase C-terminal domain 290 634 1.8E-71 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MCR_1262 2505d1e01c4ce994d39876f1b57d218a 689 Gene3D G3DSA:1.10.486.10 396 565 1.8E-115 T 14-10-2018 MCR_1262 2505d1e01c4ce994d39876f1b57d218a 689 Gene3D G3DSA:1.10.10.160 124 200 1.8E-92 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily MCR_1836 ce05e613c569b6d58587f955b4584e8c 594 SUPERFAMILY SSF81301 33 171 7.08E-35 T 14-10-2018 MCR_1836 ce05e613c569b6d58587f955b4584e8c 594 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 202 259 1.6E-10 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MCR_1836 ce05e613c569b6d58587f955b4584e8c 594 SUPERFAMILY SSF81891 173 405 1.96E-30 T 14-10-2018 MCR_1836 ce05e613c569b6d58587f955b4584e8c 594 Gene3D G3DSA:1.10.3090.10 173 419 2.5E-63 T 14-10-2018 MCR_1836 ce05e613c569b6d58587f955b4584e8c 594 Gene3D G3DSA:3.30.460.10 17 171 9.9E-47 T 14-10-2018 MCR_1836 ce05e613c569b6d58587f955b4584e8c 594 Pfam PF12626 Polymerase A arginine-rich C-terminus 312 433 1.2E-26 T 14-10-2018 IPR025866 Polymerase A arginine-rich C-terminal domain MCR_1836 ce05e613c569b6d58587f955b4584e8c 594 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 26 438 1.1E-104 T 14-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 MCR_1836 ce05e613c569b6d58587f955b4584e8c 594 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 5 586 32.019 T 14-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 MCR_1836 ce05e613c569b6d58587f955b4584e8c 594 Pfam PF01743 Poly A polymerase head domain 49 175 1.2E-29 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MCR_1523 3a078d71365dd3afd5f0cac62caf20c3 916 SUPERFAMILY SSF55021 844 909 1.54E-8 T 14-10-2018 MCR_1523 3a078d71365dd3afd5f0cac62caf20c3 916 Pfam PF01966 HD domain 483 589 3.0E-9 T 14-10-2018 IPR006674 HD domain MCR_1523 3a078d71365dd3afd5f0cac62caf20c3 916 SUPERFAMILY SSF81593 205 321 4.71E-10 T 14-10-2018 MCR_1523 3a078d71365dd3afd5f0cac62caf20c3 916 PIRSF PIRSF006288 28 916 1.6E-238 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MCR_1523 3a078d71365dd3afd5f0cac62caf20c3 916 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 57 915 2.4E-210 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MCR_1523 3a078d71365dd3afd5f0cac62caf20c3 916 SUPERFAMILY SSF109604 447 610 3.06E-12 T 14-10-2018 MCR_1523 3a078d71365dd3afd5f0cac62caf20c3 916 Pfam PF08335 GlnD PII-uridylyltransferase 191 336 5.3E-29 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MCR_1523 3a078d71365dd3afd5f0cac62caf20c3 916 Gene3D G3DSA:1.10.3210.10 472 623 1.3E-6 T 14-10-2018 MCR_1523 3a078d71365dd3afd5f0cac62caf20c3 916 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 916 217.959 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MCR_1523 3a078d71365dd3afd5f0cac62caf20c3 916 SUPERFAMILY SSF81301 34 183 1.72E-16 T 14-10-2018 MCR_1523 3a078d71365dd3afd5f0cac62caf20c3 916 SMART SM00471 476 625 3.5E-5 T 14-10-2018 IPR003607 HD/PDEase domain MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 Gene3D G3DSA:2.40.50.250 492 608 2.2E-132 T 14-10-2018 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 Gene3D G3DSA:3.30.70.870 315 599 2.2E-132 T 14-10-2018 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 SUPERFAMILY SSF52540 5 228 1.65E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 Gene3D G3DSA:3.30.70.240 398 491 2.2E-132 T 14-10-2018 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 Gene3D G3DSA:2.40.30.10 208 308 2.1E-35 T 14-10-2018 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 SUPERFAMILY SSF54980 407 522 2.88E-27 T 14-10-2018 IPR035647 EF-G domain III/V-like MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 Pfam PF03144 Elongation factor Tu domain 2 228 298 1.4E-9 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 SUPERFAMILY SSF50447 160 308 2.29E-33 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 Gene3D G3DSA:3.40.50.300 4 207 4.4E-63 T 14-10-2018 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 SUPERFAMILY SSF54980 311 396 2.55E-15 T 14-10-2018 IPR035647 EF-G domain III/V-like MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 PRINTS PR00315 GTP-binding elongation factor signature 54 62 1.7E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 PRINTS PR00315 GTP-binding elongation factor signature 132 141 1.7E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 PRINTS PR00315 GTP-binding elongation factor signature 80 90 1.7E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 PRINTS PR00315 GTP-binding elongation factor signature 96 107 1.7E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.7E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 SMART SM00838 404 492 5.1E-4 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 Pfam PF00679 Elongation factor G C-terminus 405 486 3.8E-23 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 143 1.5E-24 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 Pfam PF00009 Elongation factor Tu GTP binding domain 7 203 5.5E-52 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1697 5bde16abf1cecb7d5b308074f8a4ec13 614 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 608 8.5E-286 T 14-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 MCR_1022 de64ce42283998be64df6170eea3fb2b 356 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 352 2.0E-133 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MCR_1022 de64ce42283998be64df6170eea3fb2b 356 Gene3D G3DSA:3.40.718.10 2 356 7.4E-143 T 14-10-2018 MCR_1022 de64ce42283998be64df6170eea3fb2b 356 SUPERFAMILY SSF53659 1 356 2.88E-118 T 14-10-2018 MCR_1022 de64ce42283998be64df6170eea3fb2b 356 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 356 50.699 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MCR_1022 de64ce42283998be64df6170eea3fb2b 356 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 351 2.1E-151 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MCR_1022 de64ce42283998be64df6170eea3fb2b 356 SMART SM01329 4 352 9.3E-198 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MCR_1022 de64ce42283998be64df6170eea3fb2b 356 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 243 262 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MCR_0401 db13177e1301ef469bbd6986d06197cd 309 Gene3D G3DSA:3.40.50.620 2 182 7.1E-58 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0401 db13177e1301ef469bbd6986d06197cd 309 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 189 272 1.2E-34 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 MCR_0401 db13177e1301ef469bbd6986d06197cd 309 Gene3D G3DSA:3.40.50.1220 183 309 7.7E-55 T 14-10-2018 MCR_0401 db13177e1301ef469bbd6986d06197cd 309 Pfam PF01012 Electron transfer flavoprotein domain 4 170 3.2E-40 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MCR_0401 db13177e1301ef469bbd6986d06197cd 309 PIRSF PIRSF000089 1 309 1.3E-105 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 MCR_0401 db13177e1301ef469bbd6986d06197cd 309 SUPERFAMILY SSF52467 188 309 4.09E-44 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MCR_0401 db13177e1301ef469bbd6986d06197cd 309 SUPERFAMILY SSF52402 3 183 8.37E-56 T 14-10-2018 MCR_0401 db13177e1301ef469bbd6986d06197cd 309 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 MCR_0401 db13177e1301ef469bbd6986d06197cd 309 SMART SM00893 3 181 3.7E-53 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MCR_0668 a6e6db140c3e4f7e5c306542464cf182 349 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 4 347 1.1E-159 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MCR_0668 a6e6db140c3e4f7e5c306542464cf182 349 Pfam PF03462 PCRF domain 15 204 2.6E-56 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 MCR_0668 a6e6db140c3e4f7e5c306542464cf182 349 Gene3D G3DSA:1.20.58.410 2 100 4.3E-26 T 14-10-2018 MCR_0668 a6e6db140c3e4f7e5c306542464cf182 349 Gene3D G3DSA:3.30.70.1660 114 342 1.4E-97 T 14-10-2018 MCR_0668 a6e6db140c3e4f7e5c306542464cf182 349 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MCR_0668 a6e6db140c3e4f7e5c306542464cf182 349 Gene3D G3DSA:3.30.160.20 210 305 1.4E-97 T 14-10-2018 MCR_0668 a6e6db140c3e4f7e5c306542464cf182 349 Pfam PF00472 RF-1 domain 212 321 1.3E-42 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MCR_0668 a6e6db140c3e4f7e5c306542464cf182 349 SMART SM00937 69 179 4.0E-60 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 MCR_0668 a6e6db140c3e4f7e5c306542464cf182 349 SUPERFAMILY SSF75620 16 346 3.14E-133 T 14-10-2018 MCR_0668 a6e6db140c3e4f7e5c306542464cf182 349 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 349 38.135 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MCR_1274 94f9ec3a37ef6b8ed98ad7b1706e9ae8 159 SUPERFAMILY SSF55658 1 56 1.92E-18 T 14-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal MCR_1274 94f9ec3a37ef6b8ed98ad7b1706e9ae8 159 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.903 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1274 94f9ec3a37ef6b8ed98ad7b1706e9ae8 159 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 1.5E-22 T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1274 94f9ec3a37ef6b8ed98ad7b1706e9ae8 159 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1274 94f9ec3a37ef6b8ed98ad7b1706e9ae8 159 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 146 7.0E-48 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1274 94f9ec3a37ef6b8ed98ad7b1706e9ae8 159 SUPERFAMILY SSF55653 60 147 3.79E-24 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily MCR_1274 94f9ec3a37ef6b8ed98ad7b1706e9ae8 159 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 145 9.6E-25 T 14-10-2018 IPR020069 Ribosomal protein L9, C-terminal MCR_1274 94f9ec3a37ef6b8ed98ad7b1706e9ae8 159 Gene3D G3DSA:3.40.5.10 1 50 3.3E-23 T 14-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1274 94f9ec3a37ef6b8ed98ad7b1706e9ae8 159 Gene3D G3DSA:3.10.430.100 61 148 5.6E-27 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily MCR_0464 80dd8be978f38ba404768d60be94e2b5 178 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 175 7.0E-66 T 14-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 MCR_0464 80dd8be978f38ba404768d60be94e2b5 178 SUPERFAMILY SSF53271 8 176 6.16E-52 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MCR_0464 80dd8be978f38ba404768d60be94e2b5 178 Gene3D G3DSA:3.40.50.2020 2 178 1.1E-62 T 14-10-2018 MCR_0464 80dd8be978f38ba404768d60be94e2b5 178 Pfam PF00156 Phosphoribosyl transferase domain 15 163 9.5E-25 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MCR_1748 b742e21467ee4c4f67f5b6e941007293 420 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 42.241 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_1748 b742e21467ee4c4f67f5b6e941007293 420 SUPERFAMILY SSF55205 1 419 2.29E-139 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MCR_1748 b742e21467ee4c4f67f5b6e941007293 420 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 9 408 6.5E-103 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MCR_1748 b742e21467ee4c4f67f5b6e941007293 420 Gene3D G3DSA:3.65.10.10 6 415 4.2E-162 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MCR_1748 b742e21467ee4c4f67f5b6e941007293 420 Gene3D G3DSA:3.65.10.10 21 232 4.2E-162 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MCR_1748 b742e21467ee4c4f67f5b6e941007293 420 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 417 9.9E-168 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_1819 bfe131d4ca4622116dc4232c4816200a 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.4E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1819 bfe131d4ca4622116dc4232c4816200a 307 SUPERFAMILY SSF53850 92 298 1.49E-38 T 14-10-2018 MCR_1819 bfe131d4ca4622116dc4232c4816200a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1819 bfe131d4ca4622116dc4232c4816200a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1819 bfe131d4ca4622116dc4232c4816200a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1819 bfe131d4ca4622116dc4232c4816200a 307 Gene3D G3DSA:3.40.190.290 95 299 9.6E-41 T 14-10-2018 MCR_1819 bfe131d4ca4622116dc4232c4816200a 307 SUPERFAMILY SSF46785 3 112 4.15E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_1819 bfe131d4ca4622116dc4232c4816200a 307 Pfam PF03466 LysR substrate binding domain 91 293 7.9E-39 T 14-10-2018 IPR005119 LysR, substrate-binding MCR_1819 bfe131d4ca4622116dc4232c4816200a 307 Gene3D G3DSA:1.10.10.10 3 94 2.2E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Gene3D G3DSA:3.30.230.70 1 228 4.5E-74 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 SMART SM00322 554 619 1.6E-12 T 14-10-2018 IPR004087 K Homology domain GO:0003676 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Gene3D G3DSA:3.30.230.70 232 551 3.6E-111 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 695 29.821 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 PIRSF PIRSF005499 1 696 4.1E-286 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 SUPERFAMILY SSF54211 2 143 3.69E-43 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 SUPERFAMILY SSF50249 615 692 1.79E-21 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 SUPERFAMILY SSF55666 144 234 2.49E-29 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 240 322 2.1E-19 T 14-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 693 0.0 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 SMART SM00316 622 692 4.0E-27 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Pfam PF03725 3' exoribonuclease family, domain 2 146 205 5.7E-14 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Pfam PF03725 3' exoribonuclease family, domain 2 461 530 2.7E-6 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 SUPERFAMILY SSF54791 557 641 1.55E-23 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Pfam PF00013 KH domain 559 615 2.8E-12 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Gene3D G3DSA:2.40.50.140 624 696 5.1E-30 T 14-10-2018 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Gene3D G3DSA:3.30.1370.10 552 623 1.1E-20 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Pfam PF01138 3' exoribonuclease family, domain 1 16 140 3.5E-18 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Pfam PF01138 3' exoribonuclease family, domain 1 326 458 5.6E-20 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 SUPERFAMILY SSF54211 295 490 1.82E-46 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 SUPERFAMILY SSF46915 237 323 9.68E-15 T 14-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 Pfam PF00575 S1 RNA binding domain 621 692 1.0E-19 T 14-10-2018 IPR003029 S1 domain GO:0003676 MCR_1759 83a39ca6e603cc31ba4064af0fedeaf0 696 SUPERFAMILY SSF55666 452 549 5.23E-29 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_0362 c0261f9f1d151caccbcd6becfe0cee45 514 Gene3D G3DSA:3.40.640.10 113 372 1.4E-123 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_0362 c0261f9f1d151caccbcd6becfe0cee45 514 Gene3D G3DSA:3.90.1150.170 49 493 1.4E-123 T 14-10-2018 MCR_0362 c0261f9f1d151caccbcd6becfe0cee45 514 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 312 333 - T 14-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 MCR_0362 c0261f9f1d151caccbcd6becfe0cee45 514 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 83 428 1.7E-60 T 14-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 MCR_0362 c0261f9f1d151caccbcd6becfe0cee45 514 SUPERFAMILY SSF53383 22 497 1.32E-114 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0835 312439c7e0e6557cea049a8a5ca61bf5 191 PIRSF PIRSF000232 1 191 4.1E-60 T 14-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like MCR_0835 312439c7e0e6557cea049a8a5ca61bf5 191 SUPERFAMILY SSF55469 3 189 3.01E-33 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MCR_0835 312439c7e0e6557cea049a8a5ca61bf5 191 Pfam PF00881 Nitroreductase family 9 169 4.8E-27 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MCR_0835 312439c7e0e6557cea049a8a5ca61bf5 191 Gene3D G3DSA:3.40.109.10 4 190 7.2E-37 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MCR_0814 ba01025612fe42f0d4ff5bd8dc4995c6 225 Gene3D G3DSA:3.40.50.150 5 225 1.5E-62 T 14-10-2018 MCR_0814 ba01025612fe42f0d4ff5bd8dc4995c6 225 PIRSF PIRSF003078 11 225 5.4E-51 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MCR_0814 ba01025612fe42f0d4ff5bd8dc4995c6 225 SUPERFAMILY SSF53335 23 224 4.49E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0814 ba01025612fe42f0d4ff5bd8dc4995c6 225 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 27 221 25.887 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MCR_0814 ba01025612fe42f0d4ff5bd8dc4995c6 225 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 39 224 5.3E-45 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MCR_0814 ba01025612fe42f0d4ff5bd8dc4995c6 225 Pfam PF02527 rRNA small subunit methyltransferase G 35 212 6.9E-47 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MCR_0529 8a8ef1753ce07c0448b10ec905276182 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 66 2.1E-16 T 14-10-2018 IPR010035 ThiS, thiamine-biosynthesis MCR_0529 8a8ef1753ce07c0448b10ec905276182 66 Pfam PF02597 ThiS family 4 66 7.2E-9 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MCR_0529 8a8ef1753ce07c0448b10ec905276182 66 Gene3D G3DSA:3.10.20.30 2 66 5.2E-17 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MCR_0529 8a8ef1753ce07c0448b10ec905276182 66 SUPERFAMILY SSF54285 3 65 7.85E-14 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MCR_1637 615e047b4636f44d1a55a4d5b3664095 125 SUPERFAMILY SSF88723 2 122 4.21E-30 T 14-10-2018 IPR029060 PIN-like domain superfamily MCR_1637 615e047b4636f44d1a55a4d5b3664095 125 Gene3D G3DSA:3.40.50.1010 1 123 4.5E-33 T 14-10-2018 MCR_1637 615e047b4636f44d1a55a4d5b3664095 125 Pfam PF01850 PIN domain 3 116 3.3E-17 T 14-10-2018 IPR002716 PIN domain MCR_1637 615e047b4636f44d1a55a4d5b3664095 125 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 120 10.824 T 14-10-2018 IPR022907 VapC family GO:0004540 MCR_1189 b81dff48e980fcf230db00cdfcdf4f8d 248 SUPERFAMILY SSF53448 1 247 8.15E-24 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1189 b81dff48e980fcf230db00cdfcdf4f8d 248 Gene3D G3DSA:3.90.550.10 59 225 6.5E-6 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 Pfam PF00750 tRNA synthetases class I (R) 105 446 1.1E-158 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 SUPERFAMILY SSF52374 109 453 8.26E-95 T 14-10-2018 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 SMART SM00836 460 575 8.2E-39 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 122 133 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 Gene3D G3DSA:3.30.1360.70 1 106 4.8E-31 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 3 575 3.4E-199 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 Gene3D G3DSA:1.10.730.10 454 575 2.2E-33 T 14-10-2018 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 Pfam PF05746 DALR anticodon binding domain 460 575 1.6E-33 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 SUPERFAMILY SSF55190 1 96 1.57E-22 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 3 87 3.8E-20 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 5.1E-27 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 PRINTS PR01038 Arginyl-tRNA synthetase signature 303 324 5.1E-27 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 5.1E-27 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 5.1E-27 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 SMART SM01016 1 87 7.9E-28 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 Gene3D G3DSA:3.40.50.620 107 453 2.4E-111 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 575 27.471 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MCR_0725 3b4827b84f4d2d4d3ed77f40d44d9b70 575 SUPERFAMILY SSF47323 454 575 9.81E-37 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0794 c90d96d1788ea0b3d5a35769a7fb5019 370 Gene3D G3DSA:3.40.50.10800 215 310 6.7E-94 T 14-10-2018 MCR_0794 c90d96d1788ea0b3d5a35769a7fb5019 370 Pfam PF02445 Quinolinate synthetase A protein 47 353 6.3E-102 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MCR_0794 c90d96d1788ea0b3d5a35769a7fb5019 370 Gene3D G3DSA:3.40.50.10800 46 335 6.7E-94 T 14-10-2018 MCR_0794 c90d96d1788ea0b3d5a35769a7fb5019 370 SUPERFAMILY SSF142754 43 354 8.24E-105 T 14-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MCR_0794 c90d96d1788ea0b3d5a35769a7fb5019 370 Gene3D G3DSA:3.40.50.10800 130 353 6.7E-94 T 14-10-2018 MCR_0794 c90d96d1788ea0b3d5a35769a7fb5019 370 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 43 355 1.6E-105 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MCR_0812 3393a532b42ecc1592f6f035022e9b0a 237 SMART SM00478 58 205 7.6E-49 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MCR_0812 3393a532b42ecc1592f6f035022e9b0a 237 PIRSF PIRSF001435 19 231 4.9E-50 T 14-10-2018 MCR_0812 3393a532b42ecc1592f6f035022e9b0a 237 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 207 223 1.4E-5 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MCR_0812 3393a532b42ecc1592f6f035022e9b0a 237 Hamap MF_00942 Endonuclease III [nth]. 21 229 35.11 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MCR_0812 3393a532b42ecc1592f6f035022e9b0a 237 Gene3D G3DSA:1.10.1670.10 31 223 1.5E-71 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MCR_0812 3393a532b42ecc1592f6f035022e9b0a 237 Pfam PF00633 Helix-hairpin-helix motif 120 147 4.4E-9 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MCR_0812 3393a532b42ecc1592f6f035022e9b0a 237 SUPERFAMILY SSF48150 26 228 1.0E-67 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MCR_0812 3393a532b42ecc1592f6f035022e9b0a 237 Gene3D G3DSA:1.10.340.30 41 152 1.5E-71 T 14-10-2018 MCR_0812 3393a532b42ecc1592f6f035022e9b0a 237 ProSitePatterns PS01155 Endonuclease III family signature. 122 151 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 MCR_0812 3393a532b42ecc1592f6f035022e9b0a 237 TIGRFAM TIGR01083 nth: endonuclease III 28 214 1.3E-78 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MCR_0812 3393a532b42ecc1592f6f035022e9b0a 237 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 54 188 2.0E-18 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MCR_1904 24d85df19d511ba5b554fcfe7d536f7e 87 Pfam PF00825 Ribonuclease P 11 77 1.7E-14 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MCR_1904 24d85df19d511ba5b554fcfe7d536f7e 87 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 11 77 1.5E-13 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MCR_1904 24d85df19d511ba5b554fcfe7d536f7e 87 Gene3D G3DSA:3.30.230.10 1 84 3.6E-19 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MCR_1904 24d85df19d511ba5b554fcfe7d536f7e 87 SUPERFAMILY SSF54211 12 80 1.29E-13 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1904 24d85df19d511ba5b554fcfe7d536f7e 87 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 11 59 2.0E-8 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MCR_1269 06520cada4ac502d392759d9d1986052 141 SUPERFAMILY SSF53633 1 132 2.36E-42 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MCR_1269 06520cada4ac502d392759d9d1986052 141 PRINTS PR00474 Glutamate 5-kinase family signature 1 18 2.9E-8 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MCR_1269 06520cada4ac502d392759d9d1986052 141 PRINTS PR00474 Glutamate 5-kinase family signature 33 60 2.9E-8 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MCR_1269 06520cada4ac502d392759d9d1986052 141 PRINTS PR00474 Glutamate 5-kinase family signature 83 103 2.9E-8 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MCR_1269 06520cada4ac502d392759d9d1986052 141 Gene3D G3DSA:3.40.1160.10 1 132 1.6E-43 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MCR_1269 06520cada4ac502d392759d9d1986052 141 Pfam PF00696 Amino acid kinase family 2 109 5.9E-21 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MCR_0392 4f2616392e9ed58e7331431d63679481 150 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 7.4E-10 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site MCR_0392 4f2616392e9ed58e7331431d63679481 150 SUPERFAMILY SSF54523 28 136 5.13E-23 T 14-10-2018 MCR_0392 4f2616392e9ed58e7331431d63679481 150 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 2.1E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site MCR_0392 4f2616392e9ed58e7331431d63679481 150 PRINTS PR00813 Bacterial general secretion pathway protein G signature 42 60 4.4E-9 T 14-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MCR_0392 4f2616392e9ed58e7331431d63679481 150 PRINTS PR00813 Bacterial general secretion pathway protein G signature 6 31 4.4E-9 T 14-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MCR_0392 4f2616392e9ed58e7331431d63679481 150 Gene3D G3DSA:3.30.700.10 7 137 6.0E-26 T 14-10-2018 MCR_0392 4f2616392e9ed58e7331431d63679481 150 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site MCR_0392 4f2616392e9ed58e7331431d63679481 150 Pfam PF00114 Pilin (bacterial filament) 37 136 1.7E-18 T 14-10-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 MCR_1127 e16a9294607873ac92683bf138ee2377 137 Pfam PF01641 SelR domain 16 133 2.3E-48 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MCR_1127 e16a9294607873ac92683bf138ee2377 137 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 12 132 7.3E-48 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MCR_1127 e16a9294607873ac92683bf138ee2377 137 Gene3D G3DSA:2.170.150.20 4 137 1.2E-52 T 14-10-2018 MCR_1127 e16a9294607873ac92683bf138ee2377 137 SUPERFAMILY SSF51316 11 134 7.85E-52 T 14-10-2018 IPR011057 Mss4-like superfamily MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 SUPERFAMILY SSF48168 12 223 5.36E-70 T 14-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 147 737 3.5E-175 T 14-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 Pfam PF02867 Ribonucleotide reductase, barrel domain 225 733 5.3E-121 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 435 446 1.1E-36 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 475 498 1.1E-36 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 513 535 1.1E-36 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 541 564 1.1E-36 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 300 319 1.1E-36 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 612 639 1.1E-36 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 Gene3D G3DSA:3.20.70.20 80 743 5.7E-155 T 14-10-2018 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 144 221 1.1E-9 T 14-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 SUPERFAMILY SSF51998 224 742 5.19E-167 T 14-10-2018 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 Pfam PF03477 ATP cone domain 7 93 2.8E-16 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MCR_0846 b323bdbe98c5c09ed10134d42403a0ff 758 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 601 623 - T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 Gene3D G3DSA:3.10.350.10 719 771 6.8E-13 T 14-10-2018 IPR036779 LysM domain superfamily MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 Pfam PF01464 Transglycosylase SLT domain 158 261 8.1E-25 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 171 199 - T 14-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 SUPERFAMILY SSF54106 772 817 5.49E-10 T 14-10-2018 MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 Gene3D G3DSA:3.10.350.10 772 818 1.8E-14 T 14-10-2018 IPR036779 LysM domain superfamily MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 SUPERFAMILY SSF54106 646 690 8.37E-9 T 14-10-2018 MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 SUPERFAMILY SSF54106 570 613 1.15E-8 T 14-10-2018 MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 Gene3D G3DSA:3.10.350.10 569 613 1.5E-12 T 14-10-2018 IPR036779 LysM domain superfamily MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 SMART SM00257 646 690 8.3E-13 T 14-10-2018 IPR018392 LysM domain MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 SMART SM00257 773 817 8.5E-13 T 14-10-2018 IPR018392 LysM domain MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 SMART SM00257 724 768 1.3E-10 T 14-10-2018 IPR018392 LysM domain MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 SMART SM00257 570 614 1.1E-9 T 14-10-2018 IPR018392 LysM domain MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 SUPERFAMILY SSF54106 724 768 2.22E-8 T 14-10-2018 MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 Gene3D G3DSA:3.10.350.10 628 702 2.0E-14 T 14-10-2018 IPR036779 LysM domain superfamily MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 SUPERFAMILY SSF53955 150 306 9.34E-43 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 Pfam PF01476 LysM domain 571 613 1.7E-10 T 14-10-2018 IPR018392 LysM domain MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 Pfam PF01476 LysM domain 647 690 1.4E-9 T 14-10-2018 IPR018392 LysM domain MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 Pfam PF01476 LysM domain 774 817 4.5E-11 T 14-10-2018 IPR018392 LysM domain MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 Pfam PF01476 LysM domain 725 768 5.2E-12 T 14-10-2018 IPR018392 LysM domain MCR_1003 6a15a25ef863eeca7e262bd2c126de69 819 Gene3D G3DSA:1.10.530.10 104 296 9.0E-32 T 14-10-2018 MCR_0283 e5ad47f0971f168ebbec47fd2f8e2f3f 486 Pfam PF08245 Mur ligase middle domain 128 307 7.4E-28 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MCR_0283 e5ad47f0971f168ebbec47fd2f8e2f3f 486 Gene3D G3DSA:3.40.1190.10 112 325 1.7E-78 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_0283 e5ad47f0971f168ebbec47fd2f8e2f3f 486 Pfam PF02875 Mur ligase family, glutamate ligase domain 331 419 8.8E-21 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MCR_0283 e5ad47f0971f168ebbec47fd2f8e2f3f 486 SUPERFAMILY SSF51984 24 110 7.06E-30 T 14-10-2018 MCR_0283 e5ad47f0971f168ebbec47fd2f8e2f3f 486 SUPERFAMILY SSF53623 109 325 6.15E-69 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_0283 e5ad47f0971f168ebbec47fd2f8e2f3f 486 Gene3D G3DSA:3.40.50.720 24 111 1.9E-31 T 14-10-2018 MCR_0283 e5ad47f0971f168ebbec47fd2f8e2f3f 486 Gene3D G3DSA:3.90.190.20 326 483 1.2E-46 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_0283 e5ad47f0971f168ebbec47fd2f8e2f3f 486 SUPERFAMILY SSF53244 327 480 2.93E-41 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_0283 e5ad47f0971f168ebbec47fd2f8e2f3f 486 Pfam PF01225 Mur ligase family, catalytic domain 26 123 2.7E-28 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MCR_0283 e5ad47f0971f168ebbec47fd2f8e2f3f 486 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 25 478 7.9E-167 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0283 e5ad47f0971f168ebbec47fd2f8e2f3f 486 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 23 484 41.761 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_1070 87d39c4c94cc80ffcc25cdb7670d86ed 576 Gene3D G3DSA:3.40.50.300 374 574 9.9E-43 T 14-10-2018 MCR_1070 87d39c4c94cc80ffcc25cdb7670d86ed 576 SUPERFAMILY SSF90123 8 319 3.92E-19 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MCR_1070 87d39c4c94cc80ffcc25cdb7670d86ed 576 Gene3D G3DSA:1.20.1560.10 8 337 6.4E-10 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MCR_1070 87d39c4c94cc80ffcc25cdb7670d86ed 576 Pfam PF00005 ABC transporter 381 525 1.8E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1070 87d39c4c94cc80ffcc25cdb7670d86ed 576 SMART SM00382 384 563 7.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1070 87d39c4c94cc80ffcc25cdb7670d86ed 576 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1070 87d39c4c94cc80ffcc25cdb7670d86ed 576 SUPERFAMILY SSF52540 379 545 1.47E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1391 1f3c23a98cfd59a473d643f608ed67cd 420 Gene3D G3DSA:3.40.50.1950 11 197 3.5E-59 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MCR_1391 1f3c23a98cfd59a473d643f608ed67cd 420 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 17 412 1.1E-136 T 14-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 MCR_1391 1f3c23a98cfd59a473d643f608ed67cd 420 SUPERFAMILY SSF52507 16 186 3.27E-61 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MCR_1391 1f3c23a98cfd59a473d643f608ed67cd 420 SUPERFAMILY SSF102645 198 418 1.44E-69 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MCR_1391 1f3c23a98cfd59a473d643f608ed67cd 420 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 200 384 4.1E-68 T 14-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MCR_1391 1f3c23a98cfd59a473d643f608ed67cd 420 Gene3D G3DSA:3.40.50.10300 198 420 4.1E-72 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MCR_1391 1f3c23a98cfd59a473d643f608ed67cd 420 Pfam PF02441 Flavoprotein 17 187 8.7E-46 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MCR_1469 174a5e6fa7d59d9d256f8b57c77f3c64 325 Pfam PF08908 Domain of unknown function (DUF1852) 1 323 4.0E-169 T 14-10-2018 IPR015004 Protein of unknown function DUF1852 MCR_1778 17594dc0c4611ef20aba7157911bc565 333 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 13 319 2.0E-95 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MCR_1778 17594dc0c4611ef20aba7157911bc565 333 PIRSF PIRSF004486 10 324 3.7E-91 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MCR_1778 17594dc0c4611ef20aba7157911bc565 333 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 16 323 33.755 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MCR_1778 17594dc0c4611ef20aba7157911bc565 333 SUPERFAMILY SSF53335 40 322 1.31E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1778 17594dc0c4611ef20aba7157911bc565 333 Gene3D G3DSA:3.40.50.150 35 320 5.8E-89 T 14-10-2018 MCR_1778 17594dc0c4611ef20aba7157911bc565 333 Gene3D G3DSA:1.10.150.170 131 230 5.8E-89 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 MCR_1778 17594dc0c4611ef20aba7157911bc565 333 Pfam PF01795 MraW methylase family 13 320 2.3E-92 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MCR_1778 17594dc0c4611ef20aba7157911bc565 333 SUPERFAMILY SSF81799 133 228 2.09E-31 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 MCR_0022 8093edc215919f67789104abb0d4460a 635 SUPERFAMILY SSF100934 534 609 7.85E-7 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 Gene3D G3DSA:3.30.420.40 5 378 2.6E-167 T 14-10-2018 MCR_0022 8093edc215919f67789104abb0d4460a 635 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 602 1.1E-281 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 MCR_0022 8093edc215919f67789104abb0d4460a 635 SUPERFAMILY SSF100920 383 539 5.49E-60 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 632 35.892 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 MCR_0022 8093edc215919f67789104abb0d4460a 635 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 PRINTS PR00301 70kDa heat shock protein signature 53 61 2.3E-79 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 PRINTS PR00301 70kDa heat shock protein signature 333 349 2.3E-79 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 PRINTS PR00301 70kDa heat shock protein signature 197 207 2.3E-79 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 PRINTS PR00301 70kDa heat shock protein signature 387 406 2.3E-79 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 PRINTS PR00301 70kDa heat shock protein signature 137 157 2.3E-79 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.3E-79 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.3E-79 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 PRINTS PR00301 70kDa heat shock protein signature 468 484 2.3E-79 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 PRINTS PR00301 70kDa heat shock protein signature 364 384 2.3E-79 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 Gene3D G3DSA:2.60.34.10 382 522 4.3E-65 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 SUPERFAMILY SSF53067 2 182 4.63E-66 T 14-10-2018 MCR_0022 8093edc215919f67789104abb0d4460a 635 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 191 204 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 SUPERFAMILY SSF53067 186 381 1.1E-69 T 14-10-2018 MCR_0022 8093edc215919f67789104abb0d4460a 635 Gene3D G3DSA:3.30.420.40 179 365 2.6E-167 T 14-10-2018 MCR_0022 8093edc215919f67789104abb0d4460a 635 Gene3D G3DSA:1.20.1270.10 523 602 5.4E-18 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 Pfam PF00012 Hsp70 protein 4 602 2.8E-262 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 336 350 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MCR_0022 8093edc215919f67789104abb0d4460a 635 Gene3D G3DSA:3.90.640.10 228 315 2.6E-167 T 14-10-2018 MCR_0076 83e67fe0d60f99915cb5eb84df7e903d 913 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 155 1.1E-6 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain MCR_0076 83e67fe0d60f99915cb5eb84df7e903d 913 Gene3D G3DSA:2.170.130.10 49 165 2.6E-16 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MCR_0076 83e67fe0d60f99915cb5eb84df7e903d 913 SUPERFAMILY SSF56935 66 913 1.54E-72 T 14-10-2018 MCR_0076 83e67fe0d60f99915cb5eb84df7e903d 913 Pfam PF00593 TonB dependent receptor 364 911 3.0E-36 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 449 44.263 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 SUPERFAMILY SSF53738 166 267 3.92E-31 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 135 1.7E-40 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 SUPERFAMILY SSF55957 362 450 4.84E-20 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 Gene3D G3DSA:3.40.120.10 267 344 8.8E-64 T 14-10-2018 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 184 203 1.9E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 1.9E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 244 259 1.9E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 167 264 8.1E-20 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 268 368 1.4E-29 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 Gene3D G3DSA:3.40.120.10 185 367 8.8E-64 T 14-10-2018 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 446 1.2E-11 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 4 447 1.7E-172 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 Gene3D G3DSA:3.40.120.10 1 147 4.8E-44 T 14-10-2018 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 SUPERFAMILY SSF53738 2 191 2.71E-46 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 Gene3D G3DSA:3.30.310.50 375 451 7.9E-23 T 14-10-2018 MCR_0700 a53fdb38d9ea9ba4d9a6e1c062dfb830 451 SUPERFAMILY SSF53738 268 368 1.06E-25 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_0461 90612fc238ae45657a652b5928170026 455 SUPERFAMILY SSF51735 216 451 1.56E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0461 90612fc238ae45657a652b5928170026 455 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 226 448 6.8E-44 T 14-10-2018 MCR_0461 90612fc238ae45657a652b5928170026 455 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 220 397 6.6E-5 T 14-10-2018 MCR_0461 90612fc238ae45657a652b5928170026 455 Gene3D G3DSA:3.40.50.720 24 216 2.8E-46 T 14-10-2018 MCR_0461 90612fc238ae45657a652b5928170026 455 Gene3D G3DSA:3.40.50.720 217 454 1.0E-59 T 14-10-2018 MCR_0461 90612fc238ae45657a652b5928170026 455 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 348 376 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MCR_0461 90612fc238ae45657a652b5928170026 455 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 382 399 3.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0461 90612fc238ae45657a652b5928170026 455 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 361 380 3.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0461 90612fc238ae45657a652b5928170026 455 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 238 3.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0461 90612fc238ae45657a652b5928170026 455 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 288 299 3.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0461 90612fc238ae45657a652b5928170026 455 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 415 435 3.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1309 fb2fc536133a5b3fe943ac05fac112a9 235 Pfam PF02677 Uncharacterized BCR, COG1636 35 209 9.7E-64 T 14-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 MCR_1309 fb2fc536133a5b3fe943ac05fac112a9 235 Hamap MF_02089 Epoxyqueuosine reductase QueH [queH]. 35 211 32.288 T 14-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 MCR_0129 0278c01e59ae2b100ffa4f3fc31e96a3 63 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 1.8E-25 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MCR_0129 0278c01e59ae2b100ffa4f3fc31e96a3 63 Pfam PF01632 Ribosomal protein L35 2 59 1.9E-23 T 14-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0129 0278c01e59ae2b100ffa4f3fc31e96a3 63 PRINTS PR00064 Ribosomal protein L35 signature 19 33 2.3E-19 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MCR_0129 0278c01e59ae2b100ffa4f3fc31e96a3 63 PRINTS PR00064 Ribosomal protein L35 signature 34 52 2.3E-19 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MCR_0129 0278c01e59ae2b100ffa4f3fc31e96a3 63 PRINTS PR00064 Ribosomal protein L35 signature 2 19 2.3E-19 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MCR_0129 0278c01e59ae2b100ffa4f3fc31e96a3 63 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 62 14.123 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MCR_0129 0278c01e59ae2b100ffa4f3fc31e96a3 63 ProSitePatterns PS00936 Ribosomal protein L35 signature. 4 29 - T 14-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0129 0278c01e59ae2b100ffa4f3fc31e96a3 63 SUPERFAMILY SSF143034 1 62 3.01E-22 T 14-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0129 0278c01e59ae2b100ffa4f3fc31e96a3 63 Gene3D G3DSA:2.40.50.530 3 62 2.1E-22 T 14-10-2018 MCR_1590 a33fe8478a878e78149edf8277023b3b 492 Gene3D G3DSA:3.90.1300.10 3 490 3.1E-189 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MCR_1590 a33fe8478a878e78149edf8277023b3b 492 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 15 481 7.1E-175 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MCR_1590 a33fe8478a878e78149edf8277023b3b 492 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 482 86.991 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MCR_1590 a33fe8478a878e78149edf8277023b3b 492 SUPERFAMILY SSF75304 3 485 6.41E-156 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MCR_1590 a33fe8478a878e78149edf8277023b3b 492 Pfam PF01425 Amidase 25 471 3.6E-160 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MCR_1590 a33fe8478a878e78149edf8277023b3b 492 ProSitePatterns PS00571 Amidases signature. 152 183 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MCR_0479 ad714788476f0390c513b29ec051fb24 469 Pfam PF01136 Peptidase family U32 80 360 8.3E-96 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MCR_0479 ad714788476f0390c513b29ec051fb24 469 Gene3D G3DSA:2.40.30.10 373 447 4.3E-10 T 14-10-2018 MCR_0479 ad714788476f0390c513b29ec051fb24 469 Pfam PF16325 Peptidase family U32 C-terminal domain 377 454 1.9E-18 T 14-10-2018 IPR032525 Peptidase family U32, C-terminal MCR_0479 ad714788476f0390c513b29ec051fb24 469 ProSitePatterns PS01276 Peptidase family U32 signature. 167 185 - T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MCR_0184 ccba7e8210567983df520e48335117bd 317 Gene3D G3DSA:3.40.50.2020 148 290 4.2E-131 T 14-10-2018 MCR_0184 ccba7e8210567983df520e48335117bd 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 129 144 - T 14-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 MCR_0184 ccba7e8210567983df520e48335117bd 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 200 313 1.9E-29 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MCR_0184 ccba7e8210567983df520e48335117bd 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 4 314 2.1E-122 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MCR_0184 ccba7e8210567983df520e48335117bd 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 4 121 6.3E-49 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MCR_0184 ccba7e8210567983df520e48335117bd 317 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 4 314 48.102 T 14-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 MCR_0184 ccba7e8210567983df520e48335117bd 317 SUPERFAMILY SSF53271 69 306 6.42E-64 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MCR_0184 ccba7e8210567983df520e48335117bd 317 SMART SM01400 4 121 1.4E-75 T 14-10-2018 MCR_0184 ccba7e8210567983df520e48335117bd 317 Gene3D G3DSA:3.40.50.2020 7 302 4.2E-131 T 14-10-2018 MCR_1001 1dd30492769b00d42e32d5ccfc76a58c 610 PIRSF PIRSF001348 2 610 2.4E-270 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MCR_1001 1dd30492769b00d42e32d5ccfc76a58c 610 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 266 274 - T 14-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MCR_1001 1dd30492769b00d42e32d5ccfc76a58c 610 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 19 238 1.2E-103 T 14-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MCR_1001 1dd30492769b00d42e32d5ccfc76a58c 610 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 7 608 49.585 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MCR_1001 1dd30492769b00d42e32d5ccfc76a58c 610 Gene3D G3DSA:3.40.449.10 19 241 1.6E-260 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MCR_1001 1dd30492769b00d42e32d5ccfc76a58c 610 SUPERFAMILY SSF68923 9 241 3.56E-101 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MCR_1001 1dd30492769b00d42e32d5ccfc76a58c 610 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 242 606 8.0E-165 T 14-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MCR_1001 1dd30492769b00d42e32d5ccfc76a58c 610 SUPERFAMILY SSF53795 242 608 5.26E-150 T 14-10-2018 MCR_1001 1dd30492769b00d42e32d5ccfc76a58c 610 Gene3D G3DSA:3.90.228.20 242 604 1.6E-260 T 14-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MCR_1001 1dd30492769b00d42e32d5ccfc76a58c 610 Gene3D G3DSA:2.170.8.10 54 396 1.6E-260 T 14-10-2018 MCR_0662 bf86c7aeb21a4af545f0afd8f26cc47b 618 SMART SM00382 12 238 4.2E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0662 bf86c7aeb21a4af545f0afd8f26cc47b 618 Gene3D G3DSA:3.40.50.300 1 171 8.5E-32 T 14-10-2018 MCR_0662 bf86c7aeb21a4af545f0afd8f26cc47b 618 Pfam PF05970 PIF1-like helicase 10 305 2.6E-46 T 14-10-2018 IPR010285 DNA helicase Pif1-like GO:0000723|GO:0003678|GO:0006281 MCR_0662 bf86c7aeb21a4af545f0afd8f26cc47b 618 SUPERFAMILY SSF52540 124 412 2.04E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0662 bf86c7aeb21a4af545f0afd8f26cc47b 618 SUPERFAMILY SSF52540 3 178 9.7E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0662 bf86c7aeb21a4af545f0afd8f26cc47b 618 Pfam PF14493 Helix-turn-helix domain 508 603 7.8E-19 T 14-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MCR_1145 51cf3f07b7c555db8f97158c6b0bb219 441 SUPERFAMILY SSF56112 92 313 1.35E-20 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MCR_1145 51cf3f07b7c555db8f97158c6b0bb219 441 Pfam PF03109 ABC1 family 116 231 1.4E-28 T 14-10-2018 IPR004147 UbiB domain MCR_1145 51cf3f07b7c555db8f97158c6b0bb219 441 SMART SM00220 123 430 0.0062 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 Gene3D G3DSA:3.90.930.12 83 177 3.5E-39 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 Pfam PF00347 Ribosomal protein L6 12 82 1.1E-15 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 Pfam PF00347 Ribosomal protein L6 90 164 1.4E-19 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.907 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.4E-33 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.4E-33 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.4E-33 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 Gene3D G3DSA:3.90.930.12 1 82 1.5E-26 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 SUPERFAMILY SSF56053 83 177 3.14E-35 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.1E-72 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 14-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 SUPERFAMILY SSF56053 1 82 8.24E-24 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1570 11a4cbfa7e24bafa50b6023b02571168 177 PIRSF PIRSF002162 1 177 1.4E-45 T 14-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0287 e08adc597c3e4e6f32dca62a7f3ef335 188 PIRSF PIRSF000239 1 188 1.9E-53 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MCR_0287 e08adc597c3e4e6f32dca62a7f3ef335 188 TIGRFAM TIGR03137 AhpC: peroxiredoxin 3 188 7.2E-98 T 14-10-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MCR_0287 e08adc597c3e4e6f32dca62a7f3ef335 188 SUPERFAMILY SSF52833 4 188 2.66E-58 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0287 e08adc597c3e4e6f32dca62a7f3ef335 188 Pfam PF00578 AhpC/TSA family 5 133 4.8E-35 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MCR_0287 e08adc597c3e4e6f32dca62a7f3ef335 188 Gene3D G3DSA:3.40.30.10 1 187 1.0E-61 T 14-10-2018 MCR_0648 82549926750da7322e20d94132c9ef5b 500 Pfam PF00924 Mechanosensitive ion channel 194 393 8.9E-38 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MCR_0648 82549926750da7322e20d94132c9ef5b 500 Gene3D G3DSA:2.30.30.60 254 303 4.1E-8 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MCR_0648 82549926750da7322e20d94132c9ef5b 500 SUPERFAMILY SSF82689 306 405 8.24E-17 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MCR_0648 82549926750da7322e20d94132c9ef5b 500 Pfam PF04972 BON domain 63 125 2.9E-9 T 14-10-2018 IPR007055 BON domain MCR_0648 82549926750da7322e20d94132c9ef5b 500 SUPERFAMILY SSF82861 156 237 3.01E-7 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MCR_0648 82549926750da7322e20d94132c9ef5b 500 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 268 302 - T 14-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 MCR_0648 82549926750da7322e20d94132c9ef5b 500 Gene3D G3DSA:3.30.70.100 304 399 3.0E-12 T 14-10-2018 MCR_0648 82549926750da7322e20d94132c9ef5b 500 SUPERFAMILY SSF50182 238 304 2.06E-13 T 14-10-2018 IPR010920 LSM domain superfamily MCR_1769 217279960cfc482be9154e5d91faad96 493 Gene3D G3DSA:1.10.150.20 433 491 3.1E-17 T 14-10-2018 MCR_1769 217279960cfc482be9154e5d91faad96 493 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 342 7.2E-104 T 14-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 MCR_1769 217279960cfc482be9154e5d91faad96 493 SMART SM00316 136 203 0.0089 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_1769 217279960cfc482be9154e5d91faad96 493 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 414 26.64 T 14-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 MCR_1769 217279960cfc482be9154e5d91faad96 493 SUPERFAMILY SSF47794 359 419 6.28E-13 T 14-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 MCR_1769 217279960cfc482be9154e5d91faad96 493 Pfam PF13184 NusA-like KH domain 233 297 4.1E-25 T 14-10-2018 IPR025249 KH domain, NusA-like GO:0003723 MCR_1769 217279960cfc482be9154e5d91faad96 493 Gene3D G3DSA:3.30.300.20 202 280 1.3E-29 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MCR_1769 217279960cfc482be9154e5d91faad96 493 SUPERFAMILY SSF54814 282 344 1.18E-10 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MCR_1769 217279960cfc482be9154e5d91faad96 493 Gene3D G3DSA:2.40.50.140 138 201 3.0E-12 T 14-10-2018 MCR_1769 217279960cfc482be9154e5d91faad96 493 Pfam PF08529 NusA N-terminal domain 4 126 2.8E-32 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MCR_1769 217279960cfc482be9154e5d91faad96 493 Gene3D G3DSA:3.30.300.20 281 350 5.3E-19 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MCR_1769 217279960cfc482be9154e5d91faad96 493 SUPERFAMILY SSF54814 203 281 1.9E-27 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MCR_1769 217279960cfc482be9154e5d91faad96 493 Gene3D G3DSA:1.10.150.20 356 425 2.6E-19 T 14-10-2018 MCR_1769 217279960cfc482be9154e5d91faad96 493 SUPERFAMILY SSF50249 135 202 1.17E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1769 217279960cfc482be9154e5d91faad96 493 SUPERFAMILY SSF69705 1 128 1.19E-33 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 MCR_1769 217279960cfc482be9154e5d91faad96 493 Gene3D G3DSA:3.30.1480.10 1 131 5.0E-35 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 MCR_1769 217279960cfc482be9154e5d91faad96 493 SUPERFAMILY SSF47794 431 492 1.26E-11 T 14-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 MCR_1769 217279960cfc482be9154e5d91faad96 493 Pfam PF14520 Helix-hairpin-helix domain 434 488 2.5E-4 T 14-10-2018 MCR_0502 f2a8065c3061a690def5542a6ca57334 133 SUPERFAMILY SSF69118 8 123 3.42E-25 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MCR_0502 f2a8065c3061a690def5542a6ca57334 133 Gene3D G3DSA:1.20.1290.10 8 126 9.9E-26 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MCR_0502 f2a8065c3061a690def5542a6ca57334 133 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 119 9.5E-12 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MCR_0928 b62d7fafec079f4d8b7897102d82c4a3 200 Gene3D G3DSA:3.40.470.10 11 199 2.3E-19 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MCR_0928 b62d7fafec079f4d8b7897102d82c4a3 200 SUPERFAMILY SSF52141 15 196 1.48E-20 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MCR_0191 9e67002e90e43b1e1b0bbfcd78027ead 553 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 449 550 1.5E-49 T 14-10-2018 MCR_0191 9e67002e90e43b1e1b0bbfcd78027ead 553 Gene3D G3DSA:3.50.50.60 9 389 1.2E-186 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0191 9e67002e90e43b1e1b0bbfcd78027ead 553 Gene3D G3DSA:3.30.70.20 454 548 2.7E-38 T 14-10-2018 MCR_0191 9e67002e90e43b1e1b0bbfcd78027ead 553 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 182 197 2.6E-8 T 14-10-2018 MCR_0191 9e67002e90e43b1e1b0bbfcd78027ead 553 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 2.6E-8 T 14-10-2018 MCR_0191 9e67002e90e43b1e1b0bbfcd78027ead 553 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 338 2.6E-8 T 14-10-2018 MCR_0191 9e67002e90e43b1e1b0bbfcd78027ead 553 Pfam PF13450 NAD(P)-binding Rossmann-like domain 14 60 1.0E-6 T 14-10-2018 MCR_0191 9e67002e90e43b1e1b0bbfcd78027ead 553 SUPERFAMILY SSF51905 4 451 7.99E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0191 9e67002e90e43b1e1b0bbfcd78027ead 553 Gene3D G3DSA:3.30.9.90 82 453 1.2E-186 T 14-10-2018 MCR_0191 9e67002e90e43b1e1b0bbfcd78027ead 553 SUPERFAMILY SSF54373 214 310 5.49E-33 T 14-10-2018 MCR_0191 9e67002e90e43b1e1b0bbfcd78027ead 553 SUPERFAMILY SSF54862 453 553 1.45E-28 T 14-10-2018 MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 265 420 1.7E-36 T 14-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 SUPERFAMILY SSF54534 106 243 1.59E-35 T 14-10-2018 MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 SUPERFAMILY SSF102735 4 131 1.7E-31 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 PIRSF PIRSF003095 4 442 2.5E-124 T 14-10-2018 IPR005215 Trigger factor GO:0015031 MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 Gene3D G3DSA:3.10.50.40 152 248 6.6E-100 T 14-10-2018 MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 239 2.2E-16 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 Pfam PF05697 Bacterial trigger factor protein (TF) 7 146 1.8E-34 T 14-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 SUPERFAMILY SSF109998 250 436 1.57E-46 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 Hamap MF_00303 Trigger factor [tig]. 4 426 21.264 T 14-10-2018 IPR005215 Trigger factor GO:0015031 MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 Gene3D G3DSA:3.30.70.1050 2 117 7.9E-31 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 Gene3D G3DSA:1.10.3120.10 118 425 6.6E-100 T 14-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 MCR_0087 cbeb5b5c302440f8f5f3ae800e61b7af 444 TIGRFAM TIGR00115 tig: trigger factor 16 420 5.4E-139 T 14-10-2018 IPR005215 Trigger factor GO:0015031 MCR_0933 591632747d0bc09d5e42773f853c5574 517 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 58 508 4.0E-73 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MCR_0933 591632747d0bc09d5e42773f853c5574 517 Pfam PF13742 OB-fold nucleic acid binding domain 56 162 2.3E-16 T 14-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 MCR_0933 591632747d0bc09d5e42773f853c5574 517 Pfam PF02601 Exonuclease VII, large subunit 186 506 3.5E-58 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 MCR_0202 2494cf26b9cc3d0adb9b5bf7e7ec6b7c 222 Pfam PF05036 Sporulation related domain 145 215 2.3E-4 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 MCR_0202 2494cf26b9cc3d0adb9b5bf7e7ec6b7c 222 Gene3D G3DSA:3.30.70.1070 138 217 1.1E-7 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MCR_0202 2494cf26b9cc3d0adb9b5bf7e7ec6b7c 222 SUPERFAMILY SSF110997 142 215 3.4E-8 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MCR_0685 bfeb6d33db28ad339de059054e630455 247 Gene3D G3DSA:3.40.1280.10 76 245 1.4E-46 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MCR_0685 bfeb6d33db28ad339de059054e630455 247 Pfam PF04452 RNA methyltransferase 20 235 9.8E-64 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MCR_0685 bfeb6d33db28ad339de059054e630455 247 SUPERFAMILY SSF75217 75 239 3.05E-45 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MCR_0685 bfeb6d33db28ad339de059054e630455 247 SUPERFAMILY SSF88697 2 70 2.15E-15 T 14-10-2018 IPR015947 PUA-like superfamily MCR_0685 bfeb6d33db28ad339de059054e630455 247 Gene3D G3DSA:2.40.240.20 1 70 1.8E-19 T 14-10-2018 MCR_0685 bfeb6d33db28ad339de059054e630455 247 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 13 238 1.7E-51 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MCR_0685 bfeb6d33db28ad339de059054e630455 247 PIRSF PIRSF015601 1 241 5.2E-55 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 791 42.334 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 797 4.6E-248 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 Pfam PF03147 Ferredoxin-fold anticodon binding domain 704 797 8.9E-31 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 Gene3D G3DSA:3.30.930.10 490 692 6.8E-47 T 14-10-2018 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 SUPERFAMILY SSF55681 471 691 9.44E-42 T 14-10-2018 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 Pfam PF01588 Putative tRNA binding domain 45 149 1.4E-25 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 Pfam PF03483 B3/4 domain 216 389 2.8E-63 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 Gene3D G3DSA:2.40.50.140 39 158 9.0E-69 T 14-10-2018 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 SUPERFAMILY SSF50249 35 197 6.86E-50 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 SUPERFAMILY SSF54991 701 797 2.22E-30 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 Gene3D G3DSA:3.30.56.10 405 479 7.8E-21 T 14-10-2018 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 SMART SM00874 407 475 8.6E-22 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 SMART SM00873 216 389 9.1E-85 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 Gene3D G3DSA:3.30.56.10 4 186 9.0E-69 T 14-10-2018 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 SUPERFAMILY SSF46955 409 478 7.6E-17 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 Gene3D G3DSA:3.30.70.380 705 798 5.3E-31 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 SUPERFAMILY SSF56037 201 398 9.42E-69 T 14-10-2018 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 Pfam PF03484 tRNA synthetase B5 domain 412 475 8.0E-18 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 SMART SM00896 704 797 9.6E-43 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MCR_0141 6d53e9283f160da79f7ec8fa3d641bf9 798 Gene3D G3DSA:3.50.40.10 202 398 3.8E-73 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 MCR_0135 6b2907138277e433097cb9955241cecb 502 Gene3D G3DSA:2.60.40.420 205 376 6.5E-59 T 14-10-2018 IPR008972 Cupredoxin MCR_0135 6b2907138277e433097cb9955241cecb 502 SUPERFAMILY SSF49503 202 364 7.25E-56 T 14-10-2018 IPR008972 Cupredoxin MCR_0135 6b2907138277e433097cb9955241cecb 502 Gene3D G3DSA:1.10.760.10 377 502 1.8E-42 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_0135 6b2907138277e433097cb9955241cecb 502 SUPERFAMILY SSF46626 382 494 1.35E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_0135 6b2907138277e433097cb9955241cecb 502 Pfam PF07732 Multicopper oxidase 95 203 3.4E-12 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MCR_0135 6b2907138277e433097cb9955241cecb 502 Pfam PF00034 Cytochrome c 396 477 1.9E-10 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_0135 6b2907138277e433097cb9955241cecb 502 Gene3D G3DSA:2.60.40.420 46 201 9.8E-45 T 14-10-2018 IPR008972 Cupredoxin MCR_0135 6b2907138277e433097cb9955241cecb 502 PRINTS PR00695 Copper containing nitrite reductase signature 142 161 2.0E-29 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 MCR_0135 6b2907138277e433097cb9955241cecb 502 PRINTS PR00695 Copper containing nitrite reductase signature 107 123 2.0E-29 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 MCR_0135 6b2907138277e433097cb9955241cecb 502 PRINTS PR00695 Copper containing nitrite reductase signature 81 99 2.0E-29 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 MCR_0135 6b2907138277e433097cb9955241cecb 502 PRINTS PR00695 Copper containing nitrite reductase signature 184 200 2.0E-29 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 MCR_0135 6b2907138277e433097cb9955241cecb 502 PRINTS PR00695 Copper containing nitrite reductase signature 125 142 2.0E-29 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 MCR_0135 6b2907138277e433097cb9955241cecb 502 PRINTS PR00695 Copper containing nitrite reductase signature 167 182 2.0E-29 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 MCR_0135 6b2907138277e433097cb9955241cecb 502 SUPERFAMILY SSF49503 67 214 2.01E-44 T 14-10-2018 IPR008972 Cupredoxin MCR_0135 6b2907138277e433097cb9955241cecb 502 TIGRFAM TIGR02376 Cu_nitrite_red: nitrite reductase, copper-containing 59 364 1.9E-122 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 MCR_0388 f14e2865bbaeddd69c45a030acd99ead 82 Gene3D G3DSA:3.30.1320.10 1 82 2.2E-29 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0388 f14e2865bbaeddd69c45a030acd99ead 82 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 23.86 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0388 f14e2865bbaeddd69c45a030acd99ead 82 SUPERFAMILY SSF54565 1 79 3.27E-28 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0388 f14e2865bbaeddd69c45a030acd99ead 82 Pfam PF00886 Ribosomal protein S16 8 68 1.3E-23 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0388 f14e2865bbaeddd69c45a030acd99ead 82 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 77 1.5E-28 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1205 e0a4e47605147c2da1c46acb60cea5ec 250 Pfam PF08291 Peptidase M15 148 192 9.9E-8 T 14-10-2018 IPR013230 Peptidase M15A, C-terminal KEGG: 00550+3.4.17.14|MetaCyc: PWY-6470 MCR_1205 e0a4e47605147c2da1c46acb60cea5ec 250 SUPERFAMILY SSF55166 106 232 5.02E-14 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MCR_1205 e0a4e47605147c2da1c46acb60cea5ec 250 Gene3D G3DSA:3.30.1380.10 131 234 4.0E-7 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MCR_1821 331c63936733f0b5e72a577d3dd0244a 440 Pfam PF03471 Transporter associated domain 354 432 1.2E-21 T 14-10-2018 IPR005170 Transporter-associated domain MCR_1821 331c63936733f0b5e72a577d3dd0244a 440 Pfam PF00571 CBS domain 290 336 5.8E-5 T 14-10-2018 IPR000644 CBS domain MCR_1821 331c63936733f0b5e72a577d3dd0244a 440 Gene3D G3DSA:3.30.465.10 354 434 6.0E-29 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MCR_1821 331c63936733f0b5e72a577d3dd0244a 440 Pfam PF01595 Domain of unknown function DUF21 13 203 5.4E-39 T 14-10-2018 IPR002550 CNNM, transmembrane domain MCR_1821 331c63936733f0b5e72a577d3dd0244a 440 Gene3D G3DSA:3.10.580.10 199 353 1.6E-35 T 14-10-2018 MCR_1821 331c63936733f0b5e72a577d3dd0244a 440 SUPERFAMILY SSF56176 352 437 6.0E-23 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MCR_1821 331c63936733f0b5e72a577d3dd0244a 440 SMART SM01091 353 433 2.8E-26 T 14-10-2018 IPR005170 Transporter-associated domain MCR_1821 331c63936733f0b5e72a577d3dd0244a 440 SUPERFAMILY SSF54631 205 341 5.66E-23 T 14-10-2018 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Gene3D G3DSA:3.90.1800.10 1272 1325 2.4E-10 T 14-10-2018 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Gene3D G3DSA:2.40.270.10 1057 1262 1.1E-85 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Pfam PF04561 RNA polymerase Rpb2, domain 2 314 464 1.0E-19 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Pfam PF04561 RNA polymerase Rpb2, domain 2 154 226 3.7E-5 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Pfam PF04560 RNA polymerase Rpb2, domain 7 1286 1360 6.7E-26 T 14-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Pfam PF10385 RNA polymerase beta subunit external 1 domain 601 666 8.0E-21 T 14-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Gene3D G3DSA:3.90.1100.10 652 723 1.4E-20 T 14-10-2018 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Gene3D G3DSA:2.40.50.100 724 798 1.4E-32 T 14-10-2018 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Gene3D G3DSA:3.90.1110.10 160 256 9.1E-27 T 14-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1085 1097 - T 14-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 SUPERFAMILY SSF64484 11 1362 0.0 T 14-10-2018 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Pfam PF04565 RNA polymerase Rpb2, domain 3 523 590 4.6E-30 T 14-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Gene3D G3DSA:3.90.1110.10 316 451 1.4E-34 T 14-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Pfam PF00562 RNA polymerase Rpb2, domain 6 727 1284 1.2E-161 T 14-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Gene3D G3DSA:2.40.50.150 843 962 1.8E-43 T 14-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Gene3D G3DSA:2.40.270.10 800 842 1.3E-6 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1362 12.283 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Gene3D G3DSA:3.90.1100.10 18 159 2.4E-52 T 14-10-2018 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Gene3D G3DSA:3.90.1100.10 452 634 8.5E-70 T 14-10-2018 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1358 0.0 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0257 b00939ed15f37931a83ee36ee648efa4 1363 Pfam PF04563 RNA polymerase beta subunit 26 509 4.0E-39 T 14-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0907 b9e5d88beb759cc6323394a864e2e57d 369 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 14 264 4.1E-72 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MCR_0907 b9e5d88beb759cc6323394a864e2e57d 369 Gene3D G3DSA:3.40.50.300 18 264 2.2E-73 T 14-10-2018 MCR_0907 b9e5d88beb759cc6323394a864e2e57d 369 Pfam PF01715 IPP transferase 48 341 5.3E-71 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MCR_0907 b9e5d88beb759cc6323394a864e2e57d 369 SUPERFAMILY SSF52540 17 159 1.1E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0907 b9e5d88beb759cc6323394a864e2e57d 369 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 14 365 26.987 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MCR_0907 b9e5d88beb759cc6323394a864e2e57d 369 Gene3D G3DSA:1.10.20.140 121 192 2.2E-73 T 14-10-2018 MCR_0243 9cb27f5b99c56c142984d8550b93a49c 503 Pfam PF00425 chorismate binding enzyme 226 486 5.9E-94 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MCR_0243 9cb27f5b99c56c142984d8550b93a49c 503 PRINTS PR00095 Anthranilate synthase component I signature 334 347 1.8E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MCR_0243 9cb27f5b99c56c142984d8550b93a49c 503 PRINTS PR00095 Anthranilate synthase component I signature 443 457 1.8E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MCR_0243 9cb27f5b99c56c142984d8550b93a49c 503 PRINTS PR00095 Anthranilate synthase component I signature 428 442 1.8E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MCR_0243 9cb27f5b99c56c142984d8550b93a49c 503 PRINTS PR00095 Anthranilate synthase component I signature 348 361 1.8E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MCR_0243 9cb27f5b99c56c142984d8550b93a49c 503 SUPERFAMILY SSF56322 20 496 3.89E-147 T 14-10-2018 IPR005801 ADC synthase GO:0009058 MCR_0243 9cb27f5b99c56c142984d8550b93a49c 503 Pfam PF04715 Anthranilate synthase component I, N terminal region 30 177 4.9E-29 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MCR_0243 9cb27f5b99c56c142984d8550b93a49c 503 Gene3D G3DSA:3.60.120.10 2 500 2.0E-165 T 14-10-2018 IPR005801 ADC synthase GO:0009058 MCR_0254 fcdea849fb121abb284855ce839b15cf 233 SUPERFAMILY SSF56808 6 225 5.62E-81 T 14-10-2018 IPR023674 Ribosomal protein L1-like MCR_0254 fcdea849fb121abb284855ce839b15cf 233 PIRSF PIRSF002155 1 227 1.4E-77 T 14-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0254 fcdea849fb121abb284855ce839b15cf 233 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 14-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0254 fcdea849fb121abb284855ce839b15cf 233 Gene3D G3DSA:3.40.50.790 68 159 1.6E-77 T 14-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich MCR_0254 fcdea849fb121abb284855ce839b15cf 233 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 225 9.8E-101 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MCR_0254 fcdea849fb121abb284855ce839b15cf 233 Pfam PF00687 Ribosomal protein L1p/L10e family 37 220 1.3E-49 T 14-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein MCR_0254 fcdea849fb121abb284855ce839b15cf 233 Gene3D G3DSA:3.30.190.20 21 225 1.6E-77 T 14-10-2018 MCR_0254 fcdea849fb121abb284855ce839b15cf 233 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.748 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MCR_0078 b8c58275bd5b6553be7f751b44496381 405 Gene3D G3DSA:2.40.160.10 127 332 8.9E-7 T 14-10-2018 IPR023614 Porin domain superfamily MCR_0078 b8c58275bd5b6553be7f751b44496381 405 SUPERFAMILY SSF56935 91 402 1.7E-9 T 14-10-2018 MCR_0199 f76e1d54c1d10822c8a4168fe7919908 375 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 54 372 1.8E-117 T 14-10-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 MCR_0199 f76e1d54c1d10822c8a4168fe7919908 375 Gene3D G3DSA:3.40.50.150 133 355 1.3E-18 T 14-10-2018 MCR_0199 f76e1d54c1d10822c8a4168fe7919908 375 Pfam PF08003 Protein of unknown function (DUF1698) 54 373 9.0E-115 T 14-10-2018 IPR027555 tRNA (mo5U34)-methyltransferase-like MCR_0199 f76e1d54c1d10822c8a4168fe7919908 375 SUPERFAMILY SSF53335 141 374 2.59E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0199 f76e1d54c1d10822c8a4168fe7919908 375 Hamap MF_01590 tRNA U34 carboxymethyltransferase [cmoB]. 50 373 47.992 T 14-10-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 MCR_0180 e1dd140df3a85abfb0bb79a83f20677e 240 SUPERFAMILY SSF46894 133 236 3.12E-26 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MCR_0180 e1dd140df3a85abfb0bb79a83f20677e 240 Pfam PF00072 Response regulator receiver domain 5 121 3.5E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_0180 e1dd140df3a85abfb0bb79a83f20677e 240 SMART SM00862 158 235 2.4E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MCR_0180 e1dd140df3a85abfb0bb79a83f20677e 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 235 7.8E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MCR_0180 e1dd140df3a85abfb0bb79a83f20677e 240 SUPERFAMILY SSF52172 2 132 3.7E-39 T 14-10-2018 IPR011006 CheY-like superfamily MCR_0180 e1dd140df3a85abfb0bb79a83f20677e 240 Gene3D G3DSA:1.10.10.10 127 239 1.4E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0180 e1dd140df3a85abfb0bb79a83f20677e 240 SMART SM00448 3 120 1.1E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_0180 e1dd140df3a85abfb0bb79a83f20677e 240 Gene3D G3DSA:3.40.50.2300 1 126 3.5E-37 T 14-10-2018 MCR_1315 2bb6c4e45539cb23346f33b212f59cc7 242 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 8 231 7.0E-57 T 14-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MCR_1315 2bb6c4e45539cb23346f33b212f59cc7 242 SUPERFAMILY SSF53448 7 232 1.28E-51 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1315 2bb6c4e45539cb23346f33b212f59cc7 242 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 107 114 - T 14-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MCR_1315 2bb6c4e45539cb23346f33b212f59cc7 242 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 4 231 38.086 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MCR_1315 2bb6c4e45539cb23346f33b212f59cc7 242 Gene3D G3DSA:3.90.550.10 1 233 6.5E-66 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1315 2bb6c4e45539cb23346f33b212f59cc7 242 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 8 231 1.1E-61 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MCR_1296 cee7f2f350a1a51f0930a7526145ca1b 168 Gene3D G3DSA:3.30.160.150 30 164 1.3E-15 T 14-10-2018 MCR_1882 09b8f45f494e0d3108e70b3b0c00c0f9 310 PRINTS PR00116 Arginase signature 225 254 8.7E-43 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_1882 09b8f45f494e0d3108e70b3b0c00c0f9 310 PRINTS PR00116 Arginase signature 260 274 8.7E-43 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_1882 09b8f45f494e0d3108e70b3b0c00c0f9 310 PRINTS PR00116 Arginase signature 123 150 8.7E-43 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_1882 09b8f45f494e0d3108e70b3b0c00c0f9 310 PRINTS PR00116 Arginase signature 96 111 8.7E-43 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_1882 09b8f45f494e0d3108e70b3b0c00c0f9 310 PRINTS PR00116 Arginase signature 177 195 8.7E-43 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_1882 09b8f45f494e0d3108e70b3b0c00c0f9 310 Gene3D G3DSA:3.40.800.10 6 303 1.4E-93 T 14-10-2018 MCR_1882 09b8f45f494e0d3108e70b3b0c00c0f9 310 ProSitePatterns PS01053 Arginase family signature. 228 249 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 MCR_1882 09b8f45f494e0d3108e70b3b0c00c0f9 310 SUPERFAMILY SSF52768 6 305 2.7E-87 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily MCR_1882 09b8f45f494e0d3108e70b3b0c00c0f9 310 Pfam PF00491 Arginase family 6 298 8.0E-74 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_1882 09b8f45f494e0d3108e70b3b0c00c0f9 310 TIGRFAM TIGR01229 rocF_arginase: arginase 9 302 2.3E-87 T 14-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 MCR_1882 09b8f45f494e0d3108e70b3b0c00c0f9 310 PIRSF PIRSF036979 1 300 6.2E-30 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_1718 9e3050bfbb99e1dd0c6bbf248ab51f5d 215 Pfam PF14681 Uracil phosphoribosyltransferase 9 211 1.7E-64 T 14-10-2018 MCR_1718 9e3050bfbb99e1dd0c6bbf248ab51f5d 215 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 6 212 6.5E-87 T 14-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MCR_1718 9e3050bfbb99e1dd0c6bbf248ab51f5d 215 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 6 212 44.068 T 14-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MCR_1718 9e3050bfbb99e1dd0c6bbf248ab51f5d 215 Gene3D G3DSA:3.40.50.2020 1 212 1.4E-75 T 14-10-2018 MCR_1718 9e3050bfbb99e1dd0c6bbf248ab51f5d 215 SUPERFAMILY SSF53271 7 210 5.24E-67 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MCR_1663 c83d1e8698e4c2e6977254110ba4d95e 84 SUPERFAMILY SSF52821 3 82 3.01E-22 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MCR_1663 c83d1e8698e4c2e6977254110ba4d95e 84 SMART SM00450 3 84 1.2E-9 T 14-10-2018 IPR001763 Rhodanese-like domain MCR_1663 c83d1e8698e4c2e6977254110ba4d95e 84 Gene3D G3DSA:3.40.250.10 3 82 1.6E-22 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MCR_1663 c83d1e8698e4c2e6977254110ba4d95e 84 Pfam PF00581 Rhodanese-like domain 4 79 1.1E-12 T 14-10-2018 IPR001763 Rhodanese-like domain MCR_1331 afafb6546c86b0de9587625d0525cbb9 355 ProSitePatterns PS00483 Dihydroorotase signature 2. 254 265 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1331 afafb6546c86b0de9587625d0525cbb9 355 Hamap MF_00219 Dihydroorotase [pyrC]. 4 353 44.015 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1331 afafb6546c86b0de9587625d0525cbb9 355 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 6 352 5.8E-134 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1331 afafb6546c86b0de9587625d0525cbb9 355 PIRSF PIRSF001237 2 354 1.0E-133 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1331 afafb6546c86b0de9587625d0525cbb9 355 ProSitePatterns PS00482 Dihydroorotase signature 1. 13 21 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MCR_1331 afafb6546c86b0de9587625d0525cbb9 355 Gene3D G3DSA:3.20.20.140 4 353 1.0E-103 T 14-10-2018 MCR_1331 afafb6546c86b0de9587625d0525cbb9 355 Pfam PF01979 Amidohydrolase family 13 323 4.2E-17 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MCR_1331 afafb6546c86b0de9587625d0525cbb9 355 SUPERFAMILY SSF51556 4 352 1.65E-135 T 14-10-2018 IPR032466 Metal-dependent hydrolase MCR_1687 71e34871fe7b88c68b300258d4d807ce 866 SMART SM00843 804 866 1.0E-27 T 14-10-2018 IPR018541 FtsK gamma domain MCR_1687 71e34871fe7b88c68b300258d4d807ce 866 Pfam PF01580 FtsK/SpoIIIE family 489 702 8.1E-63 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MCR_1687 71e34871fe7b88c68b300258d4d807ce 866 SUPERFAMILY SSF46785 807 865 3.18E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_1687 71e34871fe7b88c68b300258d4d807ce 866 Gene3D G3DSA:1.10.10.10 801 865 1.4E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_1687 71e34871fe7b88c68b300258d4d807ce 866 SUPERFAMILY SSF52540 464 776 4.42E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1687 71e34871fe7b88c68b300258d4d807ce 866 Gene3D G3DSA:3.30.980.40 380 485 4.7E-33 T 14-10-2018 MCR_1687 71e34871fe7b88c68b300258d4d807ce 866 Gene3D G3DSA:3.40.50.300 486 787 5.8E-111 T 14-10-2018 MCR_1687 71e34871fe7b88c68b300258d4d807ce 866 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 23 182 3.7E-25 T 14-10-2018 IPR025199 DNA translocase FtsK, 4TM region MCR_1687 71e34871fe7b88c68b300258d4d807ce 866 Pfam PF09397 Ftsk gamma domain 807 865 9.8E-25 T 14-10-2018 IPR018541 FtsK gamma domain MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 Gene3D G3DSA:3.30.1330.10 213 430 1.9E-40 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1313 19.734 T 14-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 SUPERFAMILY SSF56042 835 1050 1.32E-40 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 Gene3D G3DSA:3.40.50.880 996 1313 2.6E-125 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1058 1311 8.0E-100 T 14-10-2018 MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 Pfam PF02769 AIR synthase related protein, C-terminal domain 852 972 4.1E-7 T 14-10-2018 IPR010918 PurM-like, C-terminal domain MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 Pfam PF02769 AIR synthase related protein, C-terminal domain 441 599 1.1E-25 T 14-10-2018 IPR010918 PurM-like, C-terminal domain MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 SUPERFAMILY SSF55326 635 830 4.71E-63 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 Gene3D G3DSA:1.10.8.750 152 212 1.1E-25 T 14-10-2018 MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 SUPERFAMILY SSF52317 1056 1311 5.13E-92 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 SUPERFAMILY SSF82697 2 149 5.23E-29 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 Gene3D G3DSA:3.30.1330.10 631 822 9.4E-24 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 Gene3D G3DSA:3.90.650.10 431 620 2.2E-55 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 SUPERFAMILY SSF109736 155 219 4.71E-22 T 14-10-2018 MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 SUPERFAMILY SSF56042 438 668 1.64E-46 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 SUPERFAMILY SSF55326 220 434 1.22E-55 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 SMART SM01211 1058 1312 4.4E-140 T 14-10-2018 MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 9 1311 0.0 T 14-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_0112 df2657b944a7b440f21bd3a931e24bf2 1313 Gene3D G3DSA:3.90.650.10 823 983 1.0E-19 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MCR_0844 4db0af759d3c5bedcb76dd9dd59a34e5 198 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 14-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 MCR_0844 4db0af759d3c5bedcb76dd9dd59a34e5 198 Gene3D G3DSA:1.10.8.420 1 52 4.0E-14 T 14-10-2018 MCR_0844 4db0af759d3c5bedcb76dd9dd59a34e5 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 85.606 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MCR_0844 4db0af759d3c5bedcb76dd9dd59a34e5 198 SUPERFAMILY SSF111304 2 197 3.92E-69 T 14-10-2018 IPR023627 Recombination protein RecR MCR_0844 4db0af759d3c5bedcb76dd9dd59a34e5 198 Pfam PF13662 Toprim domain 81 168 4.1E-20 T 14-10-2018 IPR006171 TOPRIM domain MCR_0844 4db0af759d3c5bedcb76dd9dd59a34e5 198 Gene3D G3DSA:3.40.1360.10 76 197 1.8E-42 T 14-10-2018 MCR_0844 4db0af759d3c5bedcb76dd9dd59a34e5 198 Pfam PF02132 RecR protein 39 77 9.6E-14 T 14-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger MCR_0844 4db0af759d3c5bedcb76dd9dd59a34e5 198 TIGRFAM TIGR00615 recR: recombination protein RecR 3 194 4.5E-70 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MCR_0844 4db0af759d3c5bedcb76dd9dd59a34e5 198 SMART SM00493 79 164 5.7E-11 T 14-10-2018 IPR006171 TOPRIM domain MCR_0149 fc052ddb16a3ef484ee7759f041939a3 577 SMART SM00490 272 353 2.3E-34 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0149 fc052ddb16a3ef484ee7759f041939a3 577 SMART SM00487 37 235 5.3E-57 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MCR_0149 fc052ddb16a3ef484ee7759f041939a3 577 Gene3D G3DSA:3.40.50.300 230 396 2.4E-49 T 14-10-2018 MCR_0149 fc052ddb16a3ef484ee7759f041939a3 577 Gene3D G3DSA:3.40.50.300 1 227 8.2E-77 T 14-10-2018 MCR_0149 fc052ddb16a3ef484ee7759f041939a3 577 SUPERFAMILY SSF52540 89 373 1.65E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0149 fc052ddb16a3ef484ee7759f041939a3 577 Pfam PF00271 Helicase conserved C-terminal domain 245 353 1.0E-29 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0149 fc052ddb16a3ef484ee7759f041939a3 577 Pfam PF00270 DEAD/DEAH box helicase 42 208 2.2E-47 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MCR_0149 fc052ddb16a3ef484ee7759f041939a3 577 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 169 177 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MCR_0926 aa1b876a935e3cbb6b6be8c038465036 483 Gene3D G3DSA:1.10.101.10 422 483 2.7E-8 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 MCR_0926 aa1b876a935e3cbb6b6be8c038465036 483 SUPERFAMILY SSF53955 110 411 1.5E-82 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MCR_0926 aa1b876a935e3cbb6b6be8c038465036 483 Pfam PF13406 Transglycosylase SLT domain 118 405 7.0E-89 T 14-10-2018 IPR031304 Transglycosylase SLT domain 2 MCR_0926 aa1b876a935e3cbb6b6be8c038465036 483 Pfam PF01471 Putative peptidoglycan binding domain 427 478 3.0E-6 T 14-10-2018 IPR002477 Peptidoglycan binding-like MCR_0926 aa1b876a935e3cbb6b6be8c038465036 483 Gene3D G3DSA:1.10.530.10 160 404 8.2E-67 T 14-10-2018 MCR_0926 aa1b876a935e3cbb6b6be8c038465036 483 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 118 409 3.8E-91 T 14-10-2018 IPR011970 Lytic murein transglycosylase MCR_0926 aa1b876a935e3cbb6b6be8c038465036 483 Gene3D G3DSA:1.10.8.350 132 293 8.2E-67 T 14-10-2018 MCR_0926 aa1b876a935e3cbb6b6be8c038465036 483 SUPERFAMILY SSF47090 413 481 1.07E-13 T 14-10-2018 IPR036365 PGBD-like superfamily MCR_1760 a86ebd6166c048d267b4f68c555bb284 88 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 2 88 21.735 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1760 a86ebd6166c048d267b4f68c555bb284 88 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 88 4.0E-38 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1760 a86ebd6166c048d267b4f68c555bb284 88 SMART SM01387 7 87 1.7E-49 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1760 a86ebd6166c048d267b4f68c555bb284 88 Pfam PF00312 Ribosomal protein S15 9 87 1.0E-36 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1760 a86ebd6166c048d267b4f68c555bb284 88 Gene3D G3DSA:1.10.287.10 1 88 3.2E-35 T 14-10-2018 MCR_1760 a86ebd6166c048d267b4f68c555bb284 88 ProSitePatterns PS00362 Ribosomal protein S15 signature. 38 68 - T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1760 a86ebd6166c048d267b4f68c555bb284 88 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 87 3.0E-34 T 14-10-2018 MCR_1760 a86ebd6166c048d267b4f68c555bb284 88 SUPERFAMILY SSF47060 2 88 3.83E-35 T 14-10-2018 IPR009068 S15/NS1, RNA-binding MCR_0709 24a88522928d4d4c7857873248203820 582 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 35 160 8.7E-41 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0709 24a88522928d4d4c7857873248203820 582 SUPERFAMILY SSF143243 21 212 1.44E-56 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0709 24a88522928d4d4c7857873248203820 582 Gene3D G3DSA:1.10.645.20 197 582 2.3E-143 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0709 24a88522928d4d4c7857873248203820 582 Hamap MF_01359 NADH-quinone oxidoreductase subunit C/D [nuoC]. 2 582 67.867 T 14-10-2018 IPR023062 NADH dehydrogenase, subunit CD GO:0030964|GO:0050136|GO:0055114 KEGG: 00190+1.6.5.11 MCR_0709 24a88522928d4d4c7857873248203820 582 SUPERFAMILY SSF56762 208 582 1.1E-122 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0709 24a88522928d4d4c7857873248203820 582 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 89 142 2.0E-19 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0709 24a88522928d4d4c7857873248203820 582 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 312 582 8.8E-102 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0709 24a88522928d4d4c7857873248203820 582 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 235 246 - T 14-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0709 24a88522928d4d4c7857873248203820 582 Gene3D G3DSA:3.30.460.80 5 140 2.6E-33 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0709 24a88522928d4d4c7857873248203820 582 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 194 582 40.982 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0709 24a88522928d4d4c7857873248203820 582 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 33 159 1.2E-40 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0709 24a88522928d4d4c7857873248203820 582 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 198 582 2.4E-160 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0709 24a88522928d4d4c7857873248203820 582 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 15 168 24.923 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_1329 4fbc623d6450532ae028522b018df971 166 Pfam PF03734 L,D-transpeptidase catalytic domain 5 165 9.5E-16 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MCR_1329 4fbc623d6450532ae028522b018df971 166 Gene3D G3DSA:2.40.440.10 2 166 8.9E-28 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like MCR_1329 4fbc623d6450532ae028522b018df971 166 SUPERFAMILY SSF141523 4 165 2.49E-24 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like MCR_0303 ea8d2763c43ab5df5935d55181fde6ee 122 Gene3D G3DSA:3.30.1240.10 17 113 1.8E-17 T 14-10-2018 MCR_0303 ea8d2763c43ab5df5935d55181fde6ee 122 Pfam PF08282 haloacid dehalogenase-like hydrolase 1 119 1.2E-5 T 14-10-2018 MCR_0303 ea8d2763c43ab5df5935d55181fde6ee 122 SUPERFAMILY SSF56784 2 120 1.01E-6 T 14-10-2018 IPR036412 HAD-like superfamily MCR_0966 22e5f9ac4de07a07b68594320b42e75d 272 SUPERFAMILY SSF102712 9 113 1.57E-21 T 14-10-2018 MCR_0966 22e5f9ac4de07a07b68594320b42e75d 272 Gene3D G3DSA:3.40.140.10 10 126 5.8E-19 T 14-10-2018 MCR_0966 22e5f9ac4de07a07b68594320b42e75d 272 SUPERFAMILY SSF54001 120 265 9.81E-11 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MCR_0966 22e5f9ac4de07a07b68594320b42e75d 272 Gene3D G3DSA:3.90.1720.10 127 270 6.2E-11 T 14-10-2018 MCR_0966 22e5f9ac4de07a07b68594320b42e75d 272 Pfam PF14464 Prokaryotic homologs of the JAB domain 16 95 1.9E-13 T 14-10-2018 IPR028090 JAB domain, prokaryotic MCR_0966 22e5f9ac4de07a07b68594320b42e75d 272 Pfam PF00877 NlpC/P60 family 131 263 7.2E-14 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain MCR_1062 8e82af912f9477fa2cc8b94d0d666d78 213 SUPERFAMILY SSF52172 1 134 1.21E-33 T 14-10-2018 IPR011006 CheY-like superfamily MCR_1062 8e82af912f9477fa2cc8b94d0d666d78 213 SMART SM00421 147 204 1.5E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_1062 8e82af912f9477fa2cc8b94d0d666d78 213 SUPERFAMILY SSF46894 141 210 2.45E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MCR_1062 8e82af912f9477fa2cc8b94d0d666d78 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 3.0E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_1062 8e82af912f9477fa2cc8b94d0d666d78 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 3.7E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_1062 8e82af912f9477fa2cc8b94d0d666d78 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 3.7E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_1062 8e82af912f9477fa2cc8b94d0d666d78 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 3.7E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_1062 8e82af912f9477fa2cc8b94d0d666d78 213 SMART SM00448 3 116 3.2E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_1062 8e82af912f9477fa2cc8b94d0d666d78 213 Pfam PF00072 Response regulator receiver domain 5 116 1.7E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_1062 8e82af912f9477fa2cc8b94d0d666d78 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_1062 8e82af912f9477fa2cc8b94d0d666d78 213 Gene3D G3DSA:3.40.50.12740 3 210 1.1E-61 T 14-10-2018 MCR_0720 c3c0d687d10bcffb8111c2763ee49689 575 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 10 512 9.7E-156 T 14-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0720 c3c0d687d10bcffb8111c2763ee49689 575 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 260 284 7.0E-35 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0720 c3c0d687d10bcffb8111c2763ee49689 575 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 186 210 7.0E-35 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0720 c3c0d687d10bcffb8111c2763ee49689 575 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 400 426 7.0E-35 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0720 c3c0d687d10bcffb8111c2763ee49689 575 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 151 170 7.0E-35 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0720 c3c0d687d10bcffb8111c2763ee49689 575 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 348 367 7.0E-35 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0720 c3c0d687d10bcffb8111c2763ee49689 575 Pfam PF00361 Proton-conducting membrane transporter 145 442 9.9E-69 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0346 3448c24a9ee5e2d6125a065f94292617 765 TIGRFAM TIGR00595 priA: primosomal protein N' 236 763 6.1E-168 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MCR_0346 3448c24a9ee5e2d6125a065f94292617 765 Pfam PF04851 Type III restriction enzyme, res subunit 211 375 1.2E-13 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MCR_0346 3448c24a9ee5e2d6125a065f94292617 765 Pfam PF00271 Helicase conserved C-terminal domain 542 626 2.9E-5 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0346 3448c24a9ee5e2d6125a065f94292617 765 SMART SM00487 208 402 4.1E-21 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MCR_0346 3448c24a9ee5e2d6125a065f94292617 765 Hamap MF_00983 Probable primosomal protein N' [priA]. 18 765 22.685 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MCR_0346 3448c24a9ee5e2d6125a065f94292617 765 Gene3D G3DSA:3.40.50.300 202 394 9.0E-69 T 14-10-2018 MCR_0346 3448c24a9ee5e2d6125a065f94292617 765 Gene3D G3DSA:1.10.8.630 14 126 1.0E-31 T 14-10-2018 MCR_0346 3448c24a9ee5e2d6125a065f94292617 765 SUPERFAMILY SSF52540 233 635 5.26E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0346 3448c24a9ee5e2d6125a065f94292617 765 SMART SM00490 522 626 0.0023 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 259 280 - T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 SUPERFAMILY SSF51735 74 251 4.97E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 76 393 33.883 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 Gene3D G3DSA:1.10.1040.10 260 406 2.5E-47 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 SUPERFAMILY SSF48179 250 402 3.4E-51 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 79 229 3.0E-46 T 14-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 244 268 2.8E-34 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 269 293 2.8E-34 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 130 157 2.8E-34 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 80 97 2.8E-34 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 204 224 2.8E-34 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 309 326 2.8E-34 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 Gene3D G3DSA:3.40.50.720 62 258 3.0E-58 T 14-10-2018 MCR_0836 d977de505170953e9a4cb49ae2123ab3 442 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 251 387 7.7E-48 T 14-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 4.2E-26 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 PRINTS PR01703 Manganese superoxide dismutase signature 123 131 4.2E-26 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 PRINTS PR01703 Manganese superoxide dismutase signature 165 177 4.2E-26 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 4.2E-26 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 4.2E-26 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 200 4.7E-40 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 PIRSF PIRSF000349 1 205 7.4E-80 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 SUPERFAMILY SSF46609 3 89 8.38E-36 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 Gene3D G3DSA:2.40.500.20 94 205 1.3E-49 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 Gene3D G3DSA:1.10.287.990 20 89 1.6E-28 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 89 7.9E-33 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 167 174 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0637 8ed9bb2695f6005656e8b32d197aafd3 205 SUPERFAMILY SSF54719 94 203 1.44E-45 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MCR_0270 e0c582a4e22158c7ad34591e40f4bd93 137 Gene3D G3DSA:2.20.25.10 4 37 5.9E-7 T 14-10-2018 MCR_0270 e0c582a4e22158c7ad34591e40f4bd93 137 Gene3D G3DSA:3.30.300.20 38 137 5.4E-29 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MCR_0270 e0c582a4e22158c7ad34591e40f4bd93 137 Pfam PF02566 OsmC-like protein 33 130 8.8E-19 T 14-10-2018 IPR003718 OsmC/Ohr family MCR_0270 e0c582a4e22158c7ad34591e40f4bd93 137 SUPERFAMILY SSF82784 6 136 7.07E-37 T 14-10-2018 IPR036102 OsmC/Ohr superfamily MCR_0869 25b80f3f0da980c0df11cdb264bc5a08 99 SMART SM00411 5 95 2.1E-24 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0869 25b80f3f0da980c0df11cdb264bc5a08 99 Gene3D G3DSA:4.10.520.10 5 97 3.9E-26 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MCR_0869 25b80f3f0da980c0df11cdb264bc5a08 99 Pfam PF00216 Bacterial DNA-binding protein 6 95 8.4E-23 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0869 25b80f3f0da980c0df11cdb264bc5a08 99 SUPERFAMILY SSF47729 5 95 3.53E-24 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MCR_0869 25b80f3f0da980c0df11cdb264bc5a08 99 PRINTS PR01727 Prokaryotic integration host factor signature 79 93 5.5E-15 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0869 25b80f3f0da980c0df11cdb264bc5a08 99 PRINTS PR01727 Prokaryotic integration host factor signature 63 76 5.5E-15 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0869 25b80f3f0da980c0df11cdb264bc5a08 99 PRINTS PR01727 Prokaryotic integration host factor signature 45 60 5.5E-15 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0869 25b80f3f0da980c0df11cdb264bc5a08 99 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 51 70 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 265 279 6.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 300 318 6.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 283 293 6.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 337 6.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 SMART SM00387 228 340 8.1E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 12 336 1.0E-101 T 14-10-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 Pfam PF00512 His Kinase A (phospho-acceptor) domain 119 184 1.9E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 SMART SM00388 119 185 7.1E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 Gene3D G3DSA:3.30.565.10 191 345 3.7E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 Gene3D G3DSA:1.10.287.130 112 185 1.1E-21 T 14-10-2018 MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 SUPERFAMILY SSF47384 106 185 3.73E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 SUPERFAMILY SSF55874 174 338 1.2E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_1729 cce94a753a3e879fb30181e0247bc2d9 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 230 337 4.6E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 SUPERFAMILY SSF81901 173 295 1.83E-37 T 14-10-2018 MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 Pfam PF08238 Sel1 repeat 53 70 0.0038 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 Pfam PF08238 Sel1 repeat 181 215 1.0E-10 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 Pfam PF08238 Sel1 repeat 108 142 1.1E-11 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 Pfam PF08238 Sel1 repeat 144 179 7.1E-11 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 Pfam PF08238 Sel1 repeat 72 107 1.1E-10 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 Pfam PF08238 Sel1 repeat 252 286 1.0E-6 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 Pfam PF08238 Sel1 repeat 216 250 2.7E-13 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 Gene3D G3DSA:1.25.40.10 24 160 2.2E-45 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 SUPERFAMILY SSF81901 43 187 1.31E-47 T 14-10-2018 MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 Gene3D G3DSA:1.25.40.10 163 301 5.2E-52 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 SMART SM00671 108 143 3.7E-13 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 SMART SM00671 180 215 1.2E-13 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 SMART SM00671 216 251 4.1E-15 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 SMART SM00671 252 287 1.0E-9 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 SMART SM00671 72 107 1.6E-13 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 SMART SM00671 144 179 6.6E-14 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0405 fd2483bb11d0ce2f31ef0468ba6c7a40 302 SMART SM00671 40 71 0.016 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0807 a1c1a593e41452f5c963df81dd78acb5 429 Gene3D G3DSA:3.40.440.10 6 256 5.6E-99 T 14-10-2018 MCR_0807 a1c1a593e41452f5c963df81dd78acb5 429 Pfam PF00709 Adenylosuccinate synthetase 5 421 2.1E-172 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MCR_0807 a1c1a593e41452f5c963df81dd78acb5 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 427 3.3E-175 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MCR_0807 a1c1a593e41452f5c963df81dd78acb5 429 Gene3D G3DSA:3.90.170.10 266 429 2.6E-66 T 14-10-2018 MCR_0807 a1c1a593e41452f5c963df81dd78acb5 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 14-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MCR_0807 a1c1a593e41452f5c963df81dd78acb5 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 14-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MCR_0807 a1c1a593e41452f5c963df81dd78acb5 429 SMART SM00788 4 422 1.9E-281 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MCR_0807 a1c1a593e41452f5c963df81dd78acb5 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 204.304 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MCR_0807 a1c1a593e41452f5c963df81dd78acb5 429 SUPERFAMILY SSF52540 3 427 1.38E-171 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0807 a1c1a593e41452f5c963df81dd78acb5 429 Gene3D G3DSA:1.10.300.10 108 206 5.6E-99 T 14-10-2018 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 SUPERFAMILY SSF54980 612 701 6.71E-31 T 14-10-2018 IPR035647 EF-G domain III/V-like MCR_0228 41c6169a3a1386c3dad44088e6884138 708 Hamap MF_00054_B Elongation factor G [fusA]. 6 701 111.556 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 Gene3D G3DSA:3.30.70.240 613 684 5.4E-87 T 14-10-2018 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 SUPERFAMILY SSF54211 489 608 7.33E-43 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_0228 41c6169a3a1386c3dad44088e6884138 708 SUPERFAMILY SSF52540 6 287 3.46E-105 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0228 41c6169a3a1386c3dad44088e6884138 708 Pfam PF03144 Elongation factor Tu domain 2 331 398 3.5E-17 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 701 0.0 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 2.1E-29 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 SMART SM00889 487 607 3.3E-69 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 SUPERFAMILY SSF54980 411 488 1.15E-25 T 14-10-2018 IPR035647 EF-G domain III/V-like MCR_0228 41c6169a3a1386c3dad44088e6884138 708 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.9E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.9E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.9E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.9E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.9E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 SUPERFAMILY SSF50447 271 411 9.28E-35 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MCR_0228 41c6169a3a1386c3dad44088e6884138 708 Pfam PF00679 Elongation factor G C-terminus 610 696 9.0E-32 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MCR_0228 41c6169a3a1386c3dad44088e6884138 708 Pfam PF03764 Elongation factor G, domain IV 486 607 8.0E-43 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 Gene3D G3DSA:3.30.70.870 412 487 1.5E-33 T 14-10-2018 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 Gene3D G3DSA:3.30.230.10 491 697 5.4E-87 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MCR_0228 41c6169a3a1386c3dad44088e6884138 708 Gene3D G3DSA:3.40.50.300 1 298 3.8E-111 T 14-10-2018 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 Pfam PF00009 Elongation factor Tu GTP binding domain 9 287 1.2E-64 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MCR_0228 41c6169a3a1386c3dad44088e6884138 708 Gene3D G3DSA:2.40.30.10 299 407 4.5E-44 T 14-10-2018 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 Pfam PF14492 Elongation Factor G, domain II 411 484 4.2E-35 T 14-10-2018 MCR_0228 41c6169a3a1386c3dad44088e6884138 708 SMART SM00838 609 697 2.4E-56 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MCR_1191 b5732397736695ce810fa4551717ba46 240 Gene3D G3DSA:3.40.109.10 1 240 9.2E-46 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MCR_1191 b5732397736695ce810fa4551717ba46 240 Pfam PF00881 Nitroreductase family 8 218 4.6E-29 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MCR_1191 b5732397736695ce810fa4551717ba46 240 SUPERFAMILY SSF55469 1 239 1.68E-42 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MCR_0456 5aa6333ec994fef382100f27930da788 332 PIRSF PIRSF001415 1 332 9.2E-142 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MCR_0456 5aa6333ec994fef382100f27930da788 332 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 250 262 - T 14-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MCR_0456 5aa6333ec994fef382100f27930da788 332 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 304 323 6.6E-55 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MCR_0456 5aa6333ec994fef382100f27930da788 332 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 250 266 6.6E-55 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MCR_0456 5aa6333ec994fef382100f27930da788 332 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 275 290 6.6E-55 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MCR_0456 5aa6333ec994fef382100f27930da788 332 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 128 142 6.6E-55 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MCR_0456 5aa6333ec994fef382100f27930da788 332 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 197 216 6.6E-55 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MCR_0456 5aa6333ec994fef382100f27930da788 332 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 159 178 6.6E-55 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MCR_0456 5aa6333ec994fef382100f27930da788 332 SUPERFAMILY SSF51569 4 331 6.11E-136 T 14-10-2018 MCR_0456 5aa6333ec994fef382100f27930da788 332 Gene3D G3DSA:3.20.20.70 1 332 4.1E-140 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0456 5aa6333ec994fef382100f27930da788 332 Pfam PF00490 Delta-aminolevulinic acid dehydratase 11 328 8.6E-132 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MCR_0456 5aa6333ec994fef382100f27930da788 332 SMART SM01004 8 330 2.8E-218 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MCR_1494 a26ef1dde4d1fe6efc49686b0760889a 140 Hamap MF_00580 10 kDa chaperonin [groS]. 46 139 26.075 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MCR_1494 a26ef1dde4d1fe6efc49686b0760889a 140 Gene3D G3DSA:2.30.33.40 40 140 5.6E-37 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 MCR_1494 a26ef1dde4d1fe6efc49686b0760889a 140 Pfam PF00166 Chaperonin 10 Kd subunit 46 137 1.2E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MCR_1494 a26ef1dde4d1fe6efc49686b0760889a 140 PRINTS PR00297 10kDa chaperonin signature 69 90 8.7E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MCR_1494 a26ef1dde4d1fe6efc49686b0760889a 140 PRINTS PR00297 10kDa chaperonin signature 104 116 8.7E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MCR_1494 a26ef1dde4d1fe6efc49686b0760889a 140 PRINTS PR00297 10kDa chaperonin signature 125 138 8.7E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MCR_1494 a26ef1dde4d1fe6efc49686b0760889a 140 PRINTS PR00297 10kDa chaperonin signature 47 62 8.7E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MCR_1494 a26ef1dde4d1fe6efc49686b0760889a 140 ProSitePatterns PS00681 Chaperonins cpn10 signature. 47 71 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 MCR_1494 a26ef1dde4d1fe6efc49686b0760889a 140 SUPERFAMILY SSF50129 44 139 5.06E-34 T 14-10-2018 IPR011032 GroES-like superfamily MCR_1494 a26ef1dde4d1fe6efc49686b0760889a 140 SMART SM00883 46 138 5.6E-55 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MCR_1374 8cc3b8c9394f037bb6d00f11cf269e1f 237 PIRSF PIRSF015601 1 237 3.0E-39 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MCR_1374 8cc3b8c9394f037bb6d00f11cf269e1f 237 Gene3D G3DSA:3.40.1280.10 5 236 1.6E-27 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MCR_1374 8cc3b8c9394f037bb6d00f11cf269e1f 237 Pfam PF04452 RNA methyltransferase 21 235 2.5E-38 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MCR_1374 8cc3b8c9394f037bb6d00f11cf269e1f 237 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 16 229 3.4E-24 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MCR_1374 8cc3b8c9394f037bb6d00f11cf269e1f 237 SUPERFAMILY SSF75217 74 236 6.8E-31 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MCR_0053 739026a4f7b2b00399d854b8c454bbcc 234 Gene3D G3DSA:3.30.70.1560 129 214 1.0E-46 T 14-10-2018 MCR_0053 739026a4f7b2b00399d854b8c454bbcc 234 SUPERFAMILY SSF55174 1 82 1.34E-11 T 14-10-2018 MCR_0053 739026a4f7b2b00399d854b8c454bbcc 234 SUPERFAMILY SSF55120 60 232 1.09E-37 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0053 739026a4f7b2b00399d854b8c454bbcc 234 Pfam PF01479 S4 domain 1 48 1.4E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0053 739026a4f7b2b00399d854b8c454bbcc 234 SMART SM00363 1 63 2.0E-6 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0053 739026a4f7b2b00399d854b8c454bbcc 234 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 227 1.6E-38 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MCR_0053 739026a4f7b2b00399d854b8c454bbcc 234 Pfam PF00849 RNA pseudouridylate synthase 63 196 1.7E-14 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0053 739026a4f7b2b00399d854b8c454bbcc 234 Gene3D G3DSA:3.10.290.10 1 63 1.5E-17 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MCR_0053 739026a4f7b2b00399d854b8c454bbcc 234 Gene3D G3DSA:3.30.70.580 64 231 1.0E-46 T 14-10-2018 MCR_0053 739026a4f7b2b00399d854b8c454bbcc 234 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 338 63.312 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 313 4.4E-114 T 14-10-2018 IPR017861 Kae1/TsaD family MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 1.9E-47 T 14-10-2018 IPR017861 Kae1/TsaD family MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 159 180 1.9E-47 T 14-10-2018 IPR017861 Kae1/TsaD family MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 136 148 1.9E-47 T 14-10-2018 IPR017861 Kae1/TsaD family MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.9E-47 T 14-10-2018 IPR017861 Kae1/TsaD family MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 1.9E-47 T 14-10-2018 IPR017861 Kae1/TsaD family MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 270 279 1.9E-47 T 14-10-2018 IPR017861 Kae1/TsaD family MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 Gene3D G3DSA:3.30.420.40 3 321 2.1E-125 T 14-10-2018 MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 SUPERFAMILY SSF53067 3 126 2.85E-30 T 14-10-2018 MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 Gene3D G3DSA:3.30.420.40 134 300 2.1E-125 T 14-10-2018 MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 Pfam PF00814 Glycoprotease family 28 314 6.4E-103 T 14-10-2018 IPR000905 Gcp-like domain MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 ProSitePatterns PS01016 Glycoprotease family signature. 100 120 - T 14-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 320 7.3E-130 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 MCR_0328 de6f5518d34a0d4fcdec9167dec048f0 347 SUPERFAMILY SSF53067 106 316 3.28E-41 T 14-10-2018 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 Gene3D G3DSA:3.90.740.10 233 426 0.0 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 Gene3D G3DSA:3.10.20.590 815 877 5.3E-18 T 14-10-2018 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 Gene3D G3DSA:1.10.730.10 13 807 0.0 T 14-10-2018 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 227 413 1.0E-70 T 14-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 9 875 0.0 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 Pfam PF08264 Anticodon-binding domain of tRNA 718 838 1.9E-7 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 Gene3D G3DSA:3.40.50.620 38 580 0.0 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 SUPERFAMILY SSF47323 681 875 1.09E-16 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 SUPERFAMILY SSF50677 238 427 4.4E-53 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 632 670 3.9E-7 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 430 585 3.4E-6 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 Gene3D G3DSA:3.10.330.110 581 642 0.0 T 14-10-2018 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 8 875 22.246 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 221 240 1.8E-47 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 499 517 1.8E-47 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 158 174 1.8E-47 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 190 203 1.8E-47 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 132 149 1.8E-47 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 538 560 1.8E-47 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 571 581 1.8E-47 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 Pfam PF09334 tRNA synthetases class I (M) 45 176 1.6E-18 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1295 dac4695ad175b59d3bf80f2c580c35bb 878 SUPERFAMILY SSF52374 9 679 2.5E-144 T 14-10-2018 MCR_1611 1fe01c53d85c63cccb144332cf71d870 451 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 13 321 20.421 T 14-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MCR_1611 1fe01c53d85c63cccb144332cf71d870 451 Gene3D G3DSA:3.40.50.620 15 240 8.2E-62 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_1611 1fe01c53d85c63cccb144332cf71d870 451 Pfam PF01171 PP-loop family 24 207 2.4E-45 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MCR_1611 1fe01c53d85c63cccb144332cf71d870 451 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 24 211 2.1E-46 T 14-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MCR_1611 1fe01c53d85c63cccb144332cf71d870 451 Pfam PF09179 TilS substrate binding domain 263 333 4.5E-11 T 14-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MCR_1611 1fe01c53d85c63cccb144332cf71d870 451 SUPERFAMILY SSF82829 255 336 3.92E-10 T 14-10-2018 MCR_1611 1fe01c53d85c63cccb144332cf71d870 451 SUPERFAMILY SSF52402 19 238 4.45E-47 T 14-10-2018 MCR_0108 62548574994500e2bc50943b400628a2 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 180 208 2.4E-13 T 14-10-2018 IPR003004 GspF/PilC family MCR_0108 62548574994500e2bc50943b400628a2 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 82 94 2.4E-13 T 14-10-2018 IPR003004 GspF/PilC family MCR_0108 62548574994500e2bc50943b400628a2 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 384 398 2.4E-13 T 14-10-2018 IPR003004 GspF/PilC family MCR_0108 62548574994500e2bc50943b400628a2 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 400 419 2.4E-13 T 14-10-2018 IPR003004 GspF/PilC family MCR_0108 62548574994500e2bc50943b400628a2 419 Pfam PF00482 Type II secretion system (T2SS), protein F 87 208 1.6E-26 T 14-10-2018 IPR018076 Type II secretion system F domain MCR_0108 62548574994500e2bc50943b400628a2 419 Pfam PF00482 Type II secretion system (T2SS), protein F 289 411 2.1E-28 T 14-10-2018 IPR018076 Type II secretion system F domain MCR_0108 62548574994500e2bc50943b400628a2 419 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 180 208 - T 14-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 MCR_0108 62548574994500e2bc50943b400628a2 419 Gene3D G3DSA:1.20.81.30 71 187 8.6E-26 T 14-10-2018 MCR_0108 62548574994500e2bc50943b400628a2 419 Gene3D G3DSA:1.20.81.30 273 384 1.9E-24 T 14-10-2018 MCR_0154 3dd7a571d633e21458480e94a7bcd943 309 Gene3D G3DSA:3.40.50.1100 50 153 3.9E-106 T 14-10-2018 MCR_0154 3dd7a571d633e21458480e94a7bcd943 309 Gene3D G3DSA:3.40.50.1100 23 301 3.9E-106 T 14-10-2018 MCR_0154 3dd7a571d633e21458480e94a7bcd943 309 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 45 63 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MCR_0154 3dd7a571d633e21458480e94a7bcd943 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 294 1.2E-66 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MCR_0154 3dd7a571d633e21458480e94a7bcd943 309 TIGRFAM TIGR01136 cysKM: cysteine synthase 20 305 2.0E-119 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MCR_0154 3dd7a571d633e21458480e94a7bcd943 309 SUPERFAMILY SSF53686 13 302 9.56E-89 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MCR_0154 3dd7a571d633e21458480e94a7bcd943 309 TIGRFAM TIGR01138 cysM: cysteine synthase B 18 305 1.2E-142 T 14-10-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MCR_1809 978392522fad5ac6ef1f36516c25a70a 290 SUPERFAMILY SSF53448 2 284 2.25E-56 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1809 978392522fad5ac6ef1f36516c25a70a 290 Gene3D G3DSA:3.90.550.10 2 289 3.8E-77 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1809 978392522fad5ac6ef1f36516c25a70a 290 Pfam PF00483 Nucleotidyl transferase 9 281 7.1E-28 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MCR_1107 281f2fa7ef65d6fa86abf932ae6f6c14 291 Gene3D G3DSA:3.30.1380.10 29 240 1.7E-44 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MCR_1107 281f2fa7ef65d6fa86abf932ae6f6c14 291 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 90 219 8.8E-39 T 14-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 MCR_1107 281f2fa7ef65d6fa86abf932ae6f6c14 291 SUPERFAMILY SSF55166 83 220 9.94E-29 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MCR_0917 a19dcccc93a622fd85f4591dc7856a08 484 Gene3D G3DSA:3.30.830.10 286 481 5.1E-33 T 14-10-2018 MCR_0917 a19dcccc93a622fd85f4591dc7856a08 484 Pfam PF00675 Insulinase (Peptidase family M16) 83 222 5.9E-16 T 14-10-2018 IPR011765 Peptidase M16, N-terminal MCR_0917 a19dcccc93a622fd85f4591dc7856a08 484 SUPERFAMILY SSF63411 59 267 1.34E-45 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MCR_0917 a19dcccc93a622fd85f4591dc7856a08 484 SUPERFAMILY SSF63411 290 479 3.49E-25 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MCR_0917 a19dcccc93a622fd85f4591dc7856a08 484 Pfam PF05193 Peptidase M16 inactive domain 229 406 6.6E-18 T 14-10-2018 IPR007863 Peptidase M16, C-terminal MCR_0917 a19dcccc93a622fd85f4591dc7856a08 484 Gene3D G3DSA:3.30.830.10 64 277 2.9E-48 T 14-10-2018 MCR_0067 6744cdb4a5c08f7ca2e14754efc5a9e2 117 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 16 107 6.3E-9 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0067 6744cdb4a5c08f7ca2e14754efc5a9e2 117 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 15 117 1.3E-34 T 14-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 MCR_0067 6744cdb4a5c08f7ca2e14754efc5a9e2 117 SUPERFAMILY SSF81343 10 117 3.05E-27 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0067 6744cdb4a5c08f7ca2e14754efc5a9e2 117 Gene3D G3DSA:1.20.1300.10 7 117 1.5E-29 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0067 6744cdb4a5c08f7ca2e14754efc5a9e2 117 PIRSF PIRSF000169 6 117 5.8E-41 T 14-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 MCR_1624 b13517bebb130742fa3ca538f12c7bc1 158 Pfam PF04345 Chorismate lyase 5 150 3.2E-20 T 14-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 MCR_1624 b13517bebb130742fa3ca538f12c7bc1 158 Gene3D G3DSA:3.40.1410.10 1 154 4.9E-35 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MCR_1624 b13517bebb130742fa3ca538f12c7bc1 158 SUPERFAMILY SSF64288 6 152 2.9E-31 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MCR_0011 6c6060ce9da9207b3143087535d24a81 391 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 33 270 3.1E-54 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 176 189 2.4E-18 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 73 85 2.4E-18 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 261 280 2.4E-18 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 53 71 2.4E-18 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 215 228 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site MCR_0011 6c6060ce9da9207b3143087535d24a81 391 Gene3D G3DSA:2.40.37.10 23 383 6.5E-94 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 PRINTS PR01182 Ornithine decarboxylase signature 95 119 1.8E-19 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 PRINTS PR01182 Ornithine decarboxylase signature 51 78 1.8E-19 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 PRINTS PR01182 Ornithine decarboxylase signature 25 49 1.8E-19 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 PRINTS PR01182 Ornithine decarboxylase signature 125 147 1.8E-19 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 PRINTS PR01182 Ornithine decarboxylase signature 332 342 1.8E-19 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 SUPERFAMILY SSF51419 24 273 2.91E-63 T 14-10-2018 IPR029066 PLP-binding barrel MCR_0011 6c6060ce9da9207b3143087535d24a81 391 SUPERFAMILY SSF50621 253 390 7.53E-32 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MCR_0011 6c6060ce9da9207b3143087535d24a81 391 Gene3D G3DSA:3.20.20.10 32 273 6.5E-94 T 14-10-2018 IPR029066 PLP-binding barrel MCR_0011 6c6060ce9da9207b3143087535d24a81 391 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 271 368 7.1E-14 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MCR_1064 e61a3a41247e7dc8a2f3b2993d4d521e 524 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 89 306 1.2E-75 T 14-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1064 e61a3a41247e7dc8a2f3b2993d4d521e 524 Gene3D G3DSA:3.40.720.10 12 522 2.2E-205 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MCR_1064 e61a3a41247e7dc8a2f3b2993d4d521e 524 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 11 523 48.058 T 14-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1064 e61a3a41247e7dc8a2f3b2993d4d521e 524 Gene3D G3DSA:3.40.1450.10 84 323 2.2E-205 T 14-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1064 e61a3a41247e7dc8a2f3b2993d4d521e 524 SUPERFAMILY SSF53649 14 522 1.06E-72 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MCR_1064 e61a3a41247e7dc8a2f3b2993d4d521e 524 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 13 522 9.0E-208 T 14-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1064 e61a3a41247e7dc8a2f3b2993d4d521e 524 PIRSF PIRSF001492 5 523 2.3E-199 T 14-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1064 e61a3a41247e7dc8a2f3b2993d4d521e 524 SUPERFAMILY SSF64158 84 310 2.88E-77 T 14-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1064 e61a3a41247e7dc8a2f3b2993d4d521e 524 Pfam PF01676 Metalloenzyme superfamily 13 511 3.1E-77 T 14-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 Pfam PF00702 haloacid dehalogenase-like hydrolase 420 630 5.9E-38 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 426 432 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 Pfam PF00403 Heavy-metal-associated domain 22 82 1.1E-12 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 Pfam PF00122 E1-E2 ATPase 225 404 2.8E-49 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 197 704 8.9E-72 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 Gene3D G3DSA:3.40.1110.10 435 549 2.2E-68 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 SUPERFAMILY SSF81665 196 696 1.7E-12 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 SUPERFAMILY SSF81653 227 322 2.88E-21 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 SUPERFAMILY SSF56784 422 717 1.21E-45 T 14-10-2018 IPR036412 HAD-like superfamily MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 160 719 5.3E-156 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 SUPERFAMILY SSF55008 18 87 1.44E-18 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 Gene3D G3DSA:3.30.70.100 12 87 2.6E-17 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 Gene3D G3DSA:2.70.150.20 218 329 6.4E-23 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 PRINTS PR00943 Copper-transporting ATPase signature 194 213 8.8E-17 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 PRINTS PR00943 Copper-transporting ATPase signature 407 422 8.8E-17 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 PRINTS PR00943 Copper-transporting ATPase signature 63 83 8.8E-17 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 PRINTS PR00943 Copper-transporting ATPase signature 594 611 8.8E-17 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 PRINTS PR00943 Copper-transporting ATPase signature 34 48 8.8E-17 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 PRINTS PR00943 Copper-transporting ATPase signature 347 361 8.8E-17 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 640 652 2.7E-16 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 274 288 2.7E-16 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 424 438 2.7E-16 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 564 574 2.7E-16 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 617 636 2.7E-16 T 14-10-2018 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 ProSitePatterns PS01047 Heavy-metal-associated domain. 24 53 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 Gene3D G3DSA:3.40.50.1000 405 669 2.2E-68 T 14-10-2018 IPR023214 HAD superfamily MCR_1049 2be49164adbc1d24207a8cfe9e11c382 736 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 142 720 8.4E-144 T 14-10-2018 MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 SMART SM00982 1041 1141 8.2E-47 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Gene3D G3DSA:3.90.1150.50 1038 1183 3.8E-38 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 SUPERFAMILY SSF52540 556 816 2.47E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 SMART SM00487 633 823 3.1E-26 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Gene3D G3DSA:3.40.50.11180 4 228 3.1E-37 T 14-10-2018 MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 SUPERFAMILY SSF52540 815 1023 1.74E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 SUPERFAMILY SSF52540 385 498 3.72E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 144 1115 2.5E-303 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 34 1166 26.525 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Pfam PF02559 CarD-like/TRCF domain 513 606 6.1E-21 T 14-10-2018 IPR003711 CarD-like/TRCF domain MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Pfam PF03461 TRCF domain 1043 1132 1.0E-27 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 SUPERFAMILY SSF52540 11 371 1.58E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Pfam PF00270 DEAD/DEAH box helicase 640 797 5.5E-17 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 SMART SM00490 859 943 4.1E-19 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Gene3D G3DSA:3.40.50.11180 229 374 2.4E-26 T 14-10-2018 MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Gene3D G3DSA:3.40.50.11140 383 486 1.9E-9 T 14-10-2018 MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Pfam PF00271 Helicase conserved C-terminal domain 838 942 4.7E-17 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Gene3D G3DSA:3.40.50.300 575 814 5.6E-224 T 14-10-2018 MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 SUPERFAMILY SSF141259 504 581 9.29E-20 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Gene3D G3DSA:3.40.50.300 511 1022 5.6E-224 T 14-10-2018 MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 SUPERFAMILY SSF143517 1030 1178 7.06E-37 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 SMART SM01058 512 609 1.1E-37 T 14-10-2018 IPR003711 CarD-like/TRCF domain MCR_0982 b937ea722310dcc8b1fabb5496af9a1e 1184 Gene3D G3DSA:2.30.30.840 516 574 5.6E-224 T 14-10-2018 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 Gene3D G3DSA:3.30.1490.20 119 184 2.9E-70 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 14 306 1.0E-98 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 SUPERFAMILY SSF52440 14 104 4.51E-28 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 PIRSF PIRSF039102 50 307 3.5E-78 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 PIRSF PIRSF039102 11 53 5.0E-8 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 13 307 33.73 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 Pfam PF01820 D-ala D-ala ligase N-terminus 14 94 8.5E-18 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 SUPERFAMILY SSF56059 104 304 1.15E-52 T 14-10-2018 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 Gene3D G3DSA:3.30.470.20 93 302 2.9E-70 T 14-10-2018 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 71 82 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 249 277 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 Gene3D G3DSA:3.40.50.20 6 92 1.2E-29 T 14-10-2018 MCR_0284 1d33a5b3bdb65fce25dc40720873228d 307 Pfam PF07478 D-ala D-ala ligase C-terminus 111 303 4.4E-54 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_0003 21a0ccb897e05c6038c99b4f40056377 385 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 264 384 8.9E-20 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MCR_0003 21a0ccb897e05c6038c99b4f40056377 385 Pfam PF02767 DNA polymerase III beta subunit, central domain 133 262 1.1E-22 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 MCR_0003 21a0ccb897e05c6038c99b4f40056377 385 PIRSF PIRSF000804 1 385 4.5E-91 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MCR_0003 21a0ccb897e05c6038c99b4f40056377 385 SUPERFAMILY SSF55979 264 384 6.67E-26 T 14-10-2018 MCR_0003 21a0ccb897e05c6038c99b4f40056377 385 SUPERFAMILY SSF55979 1 120 8.24E-22 T 14-10-2018 MCR_0003 21a0ccb897e05c6038c99b4f40056377 385 Gene3D G3DSA:3.10.150.10 1 261 4.1E-99 T 14-10-2018 MCR_0003 21a0ccb897e05c6038c99b4f40056377 385 Gene3D G3DSA:3.70.10.10 141 383 4.1E-99 T 14-10-2018 MCR_0003 21a0ccb897e05c6038c99b4f40056377 385 SUPERFAMILY SSF55979 131 224 3.05E-18 T 14-10-2018 MCR_0003 21a0ccb897e05c6038c99b4f40056377 385 SMART SM00480 17 381 1.1E-63 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MCR_0003 21a0ccb897e05c6038c99b4f40056377 385 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 384 1.1E-76 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MCR_0003 21a0ccb897e05c6038c99b4f40056377 385 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 122 2.2E-22 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MCR_0905 7ed6d19d59a504f396c3beb62452b8f9 198 SUPERFAMILY SSF55620 1 145 6.67E-32 T 14-10-2018 MCR_0905 7ed6d19d59a504f396c3beb62452b8f9 198 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 3 145 2.5E-27 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 MCR_0905 7ed6d19d59a504f396c3beb62452b8f9 198 Gene3D G3DSA:3.30.479.10 1 146 6.9E-24 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 MCR_0749 b483b12d5559d58827954cf8db4708ce 234 Pfam PF02665 Nitrate reductase gamma subunit 12 231 1.5E-77 T 14-10-2018 IPR023234 NarG-like domain MCR_0749 b483b12d5559d58827954cf8db4708ce 234 Gene3D G3DSA:1.20.950.20 7 223 1.4E-74 T 14-10-2018 MCR_0749 b483b12d5559d58827954cf8db4708ce 234 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 10 231 2.5E-76 T 14-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 MCR_0749 b483b12d5559d58827954cf8db4708ce 234 SUPERFAMILY SSF103501 8 231 5.49E-67 T 14-10-2018 IPR036197 NarG-like superfamily MCR_1610 1b0341a1d43716b80f82cc589c0e04ce 281 PIRSF PIRSF000193 9 276 2.8E-68 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MCR_1610 1b0341a1d43716b80f82cc589c0e04ce 281 SUPERFAMILY SSF48179 170 276 1.68E-31 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MCR_1610 1b0341a1d43716b80f82cc589c0e04ce 281 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 10 273 24.381 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MCR_1610 1b0341a1d43716b80f82cc589c0e04ce 281 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 11 108 3.1E-16 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MCR_1610 1b0341a1d43716b80f82cc589c0e04ce 281 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 171 273 1.6E-33 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MCR_1610 1b0341a1d43716b80f82cc589c0e04ce 281 Gene3D G3DSA:3.40.50.720 5 172 1.2E-38 T 14-10-2018 MCR_1610 1b0341a1d43716b80f82cc589c0e04ce 281 Gene3D G3DSA:1.10.3730.10 173 278 1.9E-35 T 14-10-2018 MCR_1610 1b0341a1d43716b80f82cc589c0e04ce 281 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 12 273 1.7E-69 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MCR_1610 1b0341a1d43716b80f82cc589c0e04ce 281 SUPERFAMILY SSF51735 10 168 5.47E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 Gene3D G3DSA:3.40.605.10 561 1000 9.2E-132 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 Pfam PF00171 Aldehyde dehydrogenase family 564 1002 8.3E-106 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 SUPERFAMILY SSF81935 8 178 7.59E-62 T 14-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 Gene3D G3DSA:3.20.20.220 131 514 9.2E-143 T 14-10-2018 MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 SUPERFAMILY SSF51730 179 521 2.67E-119 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 SUPERFAMILY SSF53720 561 1002 7.72E-115 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 Gene3D G3DSA:3.20.20.220 8 101 4.3E-12 T 14-10-2018 MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 65 176 5.7E-45 T 14-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 PIRSF PIRSF000197 1 1194 0.0 T 14-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 Pfam PF01619 Proline dehydrogenase 189 479 1.5E-98 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 515 1002 1.1E-223 T 14-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 Gene3D G3DSA:3.40.309.10 782 972 9.2E-132 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MCR_0915 0469abe411d48ee64a92dbc18317563c 1194 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 807 818 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MCR_0930 8e07983526492774ffbea861ce42c38d 685 Gene3D G3DSA:3.40.50.300 217 430 1.2E-52 T 14-10-2018 MCR_0930 8e07983526492774ffbea861ce42c38d 685 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 210 677 2.9E-113 T 14-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 MCR_0930 8e07983526492774ffbea861ce42c38d 685 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 12 678 45.575 T 14-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 MCR_0930 8e07983526492774ffbea861ce42c38d 685 Pfam PF13538 UvrD-like helicase C-terminal domain 609 655 1.8E-13 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain MCR_0930 8e07983526492774ffbea861ce42c38d 685 SUPERFAMILY SSF52540 241 660 1.79E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0930 8e07983526492774ffbea861ce42c38d 685 Pfam PF13604 AAA domain 247 445 5.4E-36 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 Gene3D G3DSA:3.50.50.60 5 344 7.5E-111 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 SUPERFAMILY SSF51905 1 347 2.59E-62 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 44 59 3.0E-67 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.0E-67 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 288 3.0E-67 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 3.0E-67 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 159 3.0E-67 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 352 373 3.0E-67 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 3.0E-67 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 459 3.0E-67 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 186 211 3.0E-67 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PIRSF PIRSF000350 1 472 5.4E-85 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 Gene3D G3DSA:3.30.390.30 356 481 7.7E-41 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 474 1.4E-152 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 Gene3D G3DSA:3.50.50.60 166 287 7.5E-111 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 337 6.2E-67 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.8E-34 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.8E-34 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 1.8E-34 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 186 204 1.8E-34 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 289 1.8E-34 T 14-10-2018 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 358 465 4.0E-32 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 SUPERFAMILY SSF55424 352 475 9.28E-37 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MCR_0073 f54f4a2f9a8c4c245d50bf9e1ab97a8e 482 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 45 55 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MCR_1354 d75a00628df8a673880903e634a63cdd 128 Pfam PF00380 Ribosomal protein S9/S16 8 128 3.6E-44 T 14-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 MCR_1354 d75a00628df8a673880903e634a63cdd 128 SUPERFAMILY SSF54211 5 128 1.56E-46 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1354 d75a00628df8a673880903e634a63cdd 128 Gene3D G3DSA:3.30.230.10 1 128 2.4E-50 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MCR_1354 d75a00628df8a673880903e634a63cdd 128 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 128 30.846 T 14-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid MCR_1354 d75a00628df8a673880903e634a63cdd 128 ProSitePatterns PS00360 Ribosomal protein S9 signature. 67 85 - T 14-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 Gene3D G3DSA:3.65.10.10 340 754 1.7E-152 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 340 761 7.5E-126 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 336 763 32.463 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 333 755 1.3E-114 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 Gene3D G3DSA:1.10.3660.10 196 300 1.5E-34 T 14-10-2018 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 Gene3D G3DSA:3.65.10.10 348 557 1.7E-152 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 SUPERFAMILY SSF48179 193 300 4.99E-33 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 ProSitePatterns PS00885 EPSP synthase signature 2. 667 685 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 ProSitePatterns PS00104 EPSP synthase signature 1. 414 428 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 Gene3D G3DSA:3.40.50.720 9 195 9.8E-44 T 14-10-2018 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 SUPERFAMILY SSF51735 11 189 5.84E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 SUPERFAMILY SSF55205 330 761 6.28E-128 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MCR_0888 8c9eb56fb24285b8eaa028641f844b1c 767 Pfam PF02153 Prephenate dehydrogenase 42 291 2.5E-69 T 14-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 477 782 3.8E-62 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 Gene3D G3DSA:3.50.30.10 361 478 3.1E-39 T 14-10-2018 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 SUPERFAMILY SSF56059 6 385 6.24E-103 T 14-10-2018 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 SUPERFAMILY SSF51621 463 792 9.95E-99 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 415 426 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 346 2.6E-118 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 Pfam PF00391 PEP-utilising enzyme, mobile domain 385 456 6.0E-24 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 787 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 PIRSF PIRSF000854 1 795 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 695 710 1.0E-5 T 14-10-2018 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 712 727 1.0E-5 T 14-10-2018 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 748 760 1.0E-5 T 14-10-2018 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 Gene3D G3DSA:3.30.470.20 194 357 7.0E-56 T 14-10-2018 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 Gene3D G3DSA:3.20.20.60 479 791 6.6E-100 T 14-10-2018 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 Gene3D G3DSA:3.30.1490.20 3 193 2.4E-70 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 695 713 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 MCR_1104 a38a7db251db05abd88639ea49d6143d 798 SUPERFAMILY SSF52009 352 467 4.71E-32 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MCR_0433 9ee1bd7ba4a4fc7a8bbb3950deb87df7 225 Pfam PF05257 CHAP domain 109 177 5.8E-7 T 14-10-2018 IPR007921 CHAP domain MCR_0433 9ee1bd7ba4a4fc7a8bbb3950deb87df7 225 SUPERFAMILY SSF54001 111 209 3.58E-7 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MCR_0433 9ee1bd7ba4a4fc7a8bbb3950deb87df7 225 Gene3D G3DSA:3.90.1720.10 91 206 2.3E-28 T 14-10-2018 MCR_0998 192dd3e3efe5c3cca3678472e3c169a5 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 274 1.2E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_0998 192dd3e3efe5c3cca3678472e3c169a5 279 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 20 275 6.2E-92 T 14-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 MCR_0998 192dd3e3efe5c3cca3678472e3c169a5 279 SUPERFAMILY SSF161098 18 271 6.41E-50 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0998 192dd3e3efe5c3cca3678472e3c169a5 279 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 21 278 9.8E-111 T 14-10-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 MCR_0998 192dd3e3efe5c3cca3678472e3c169a5 279 Gene3D G3DSA:1.10.3720.10 23 278 9.3E-58 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0293 ad84507e1eb3e076a85be9ee86c6e118 339 SMART SM00382 26 211 1.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0293 ad84507e1eb3e076a85be9ee86c6e118 339 Gene3D G3DSA:3.40.50.300 1 237 2.8E-71 T 14-10-2018 MCR_0293 ad84507e1eb3e076a85be9ee86c6e118 339 SUPERFAMILY SSF52540 1 236 3.14E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0293 ad84507e1eb3e076a85be9ee86c6e118 339 Pfam PF08402 TOBE domain 269 333 7.8E-7 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MCR_0293 ad84507e1eb3e076a85be9ee86c6e118 339 Pfam PF00005 ABC transporter 17 161 5.8E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0293 ad84507e1eb3e076a85be9ee86c6e118 339 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0293 ad84507e1eb3e076a85be9ee86c6e118 339 SUPERFAMILY SSF50331 254 333 1.81E-7 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MCR_0791 7d3a4d811e5a5d442efd7ffb0bced807 285 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 17 283 5.2E-93 T 14-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 MCR_0791 7d3a4d811e5a5d442efd7ffb0bced807 285 SUPERFAMILY SSF51690 117 283 5.49E-54 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MCR_0791 7d3a4d811e5a5d442efd7ffb0bced807 285 Gene3D G3DSA:3.90.1170.20 19 282 1.1E-97 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 MCR_0791 7d3a4d811e5a5d442efd7ffb0bced807 285 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 27 115 7.1E-24 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MCR_0791 7d3a4d811e5a5d442efd7ffb0bced807 285 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 117 282 3.3E-54 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 MCR_0791 7d3a4d811e5a5d442efd7ffb0bced807 285 PIRSF PIRSF006250 11 285 8.4E-88 T 14-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 MCR_0791 7d3a4d811e5a5d442efd7ffb0bced807 285 Gene3D G3DSA:3.20.20.70 120 273 1.1E-97 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0791 7d3a4d811e5a5d442efd7ffb0bced807 285 SUPERFAMILY SSF54675 9 116 2.63E-28 T 14-10-2018 MCR_0620 70906cd21cb7346720c201995d444a55 81 Gene3D G3DSA:1.10.10.60 1 80 1.0E-24 T 14-10-2018 MCR_0620 70906cd21cb7346720c201995d444a55 81 SUPERFAMILY SSF46689 3 80 1.64E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MCR_0620 70906cd21cb7346720c201995d444a55 81 Pfam PF02954 Bacterial regulatory protein, Fis family 38 76 4.0E-16 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MCR_0620 70906cd21cb7346720c201995d444a55 81 PIRSF PIRSF002097 1 81 4.1E-24 T 14-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MCR_0620 70906cd21cb7346720c201995d444a55 81 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 61 81 1.9E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MCR_0620 70906cd21cb7346720c201995d444a55 81 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 44 61 1.9E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 SUPERFAMILY SSF140990 412 608 4.45E-68 T 14-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 SMART SM00382 194 333 5.3E-25 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 ProSitePatterns PS00674 AAA-protein family signature. 301 319 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 Gene3D G3DSA:1.20.58.760 407 605 1.3E-67 T 14-10-2018 MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 SUPERFAMILY SSF52540 152 401 1.8E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 105 598 1.4E-228 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 Gene3D G3DSA:2.40.50.920 27 102 1.9E-12 T 14-10-2018 MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 Gene3D G3DSA:3.40.50.300 146 332 8.8E-70 T 14-10-2018 MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 330 2.9E-46 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 Gene3D G3DSA:1.10.8.60 333 406 8.0E-28 T 14-10-2018 MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 Pfam PF01434 Peptidase family M41 392 597 8.1E-75 T 14-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 Pfam PF06480 FtsH Extracellular 9 94 1.4E-7 T 14-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 MCR_0437 e2d9c14572d7a8b41c4bcd05c48ec108 634 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 7 626 36.349 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MCR_1096 9651cc70dce7cc1f1d6811e74eae21d3 264 SUPERFAMILY SSF53448 10 221 5.2E-11 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1096 9651cc70dce7cc1f1d6811e74eae21d3 264 Gene3D G3DSA:3.90.550.20 62 175 1.6E-7 T 14-10-2018 MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 Pfam PF00270 DEAD/DEAH box helicase 277 436 1.9E-18 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 SUPERFAMILY SSF52540 394 602 2.44E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 Pfam PF17191 RecG wedge domain 15 169 1.5E-24 T 14-10-2018 IPR033454 RecG, wedge domain MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 SUPERFAMILY SSF52540 224 458 9.49E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 SUPERFAMILY SSF50249 4 169 4.28E-33 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 SMART SM00490 509 592 1.4E-21 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 SMART SM00487 271 464 2.0E-32 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 Pfam PF00271 Helicase conserved C-terminal domain 482 591 1.8E-17 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 29 665 9.0E-212 T 14-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 Gene3D G3DSA:3.40.50.300 216 455 2.1E-81 T 14-10-2018 MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 Gene3D G3DSA:3.40.50.300 462 633 4.5E-53 T 14-10-2018 MCR_0098 161d94b4461b2c3d5ad00de7c6615908 698 Gene3D G3DSA:2.40.50.140 48 139 3.0E-10 T 14-10-2018 MCR_0060 7fd9126b41031d44301cccadca8e3412 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 237 7.1E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MCR_0060 7fd9126b41031d44301cccadca8e3412 244 SUPERFAMILY SSF46894 143 239 4.54E-27 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MCR_0060 7fd9126b41031d44301cccadca8e3412 244 Gene3D G3DSA:1.10.10.10 135 243 2.2E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0060 7fd9126b41031d44301cccadca8e3412 244 Pfam PF00072 Response regulator receiver domain 12 122 5.6E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_0060 7fd9126b41031d44301cccadca8e3412 244 SUPERFAMILY SSF52172 5 131 8.97E-44 T 14-10-2018 IPR011006 CheY-like superfamily MCR_0060 7fd9126b41031d44301cccadca8e3412 244 SMART SM00862 161 237 3.9E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MCR_0060 7fd9126b41031d44301cccadca8e3412 244 SMART SM00448 10 121 8.5E-46 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_0060 7fd9126b41031d44301cccadca8e3412 244 Gene3D G3DSA:3.40.50.2300 1 131 2.1E-42 T 14-10-2018 MCR_1268 c6370deab9daa7fd5ff8897745487867 154 Pfam PF00692 dUTPase 19 152 1.3E-32 T 14-10-2018 IPR029054 dUTPase-like MCR_1268 c6370deab9daa7fd5ff8897745487867 154 SUPERFAMILY SSF51283 15 153 2.49E-49 T 14-10-2018 IPR036157 dUTPase-like superfamily MCR_1268 c6370deab9daa7fd5ff8897745487867 154 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 153 31.145 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 MCR_1268 c6370deab9daa7fd5ff8897745487867 154 Gene3D G3DSA:2.70.40.10 1 153 8.9E-51 T 14-10-2018 IPR036157 dUTPase-like superfamily MCR_1268 c6370deab9daa7fd5ff8897745487867 154 TIGRFAM TIGR00576 dut: dUTP diphosphatase 16 153 3.5E-43 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 MCR_1768 08655033365fda61bec40feb99c7826c 912 SUPERFAMILY SSF52156 691 820 2.22E-36 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily MCR_1768 08655033365fda61bec40feb99c7826c 912 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 338 386 2.2E-11 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal MCR_1768 08655033365fda61bec40feb99c7826c 912 Gene3D G3DSA:2.40.30.10 584 702 5.2E-40 T 14-10-2018 MCR_1768 08655033365fda61bec40feb99c7826c 912 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 910 16.832 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MCR_1768 08655033365fda61bec40feb99c7826c 912 SUPERFAMILY SSF46955 3 50 9.89E-7 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MCR_1768 08655033365fda61bec40feb99c7826c 912 ProSitePatterns PS01176 Initiation factor 2 signature. 864 886 - T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MCR_1768 08655033365fda61bec40feb99c7826c 912 Pfam PF11987 Translation-initiation factor 2 699 803 6.2E-35 T 14-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MCR_1768 08655033365fda61bec40feb99c7826c 912 Gene3D G3DSA:2.40.30.10 815 911 2.5E-28 T 14-10-2018 MCR_1768 08655033365fda61bec40feb99c7826c 912 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 58 95 7.9E-6 T 14-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial MCR_1768 08655033365fda61bec40feb99c7826c 912 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 415 571 6.0E-32 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MCR_1768 08655033365fda61bec40feb99c7826c 912 SUPERFAMILY SSF52540 407 578 1.27E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1768 08655033365fda61bec40feb99c7826c 912 Gene3D G3DSA:3.40.50.300 410 583 1.7E-70 T 14-10-2018 MCR_1768 08655033365fda61bec40feb99c7826c 912 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 331 911 1.7E-247 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MCR_1768 08655033365fda61bec40feb99c7826c 912 Gene3D G3DSA:3.30.56.50 2 50 3.4E-6 T 14-10-2018 MCR_1768 08655033365fda61bec40feb99c7826c 912 SUPERFAMILY SSF50447 815 910 6.6E-27 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MCR_1768 08655033365fda61bec40feb99c7826c 912 SUPERFAMILY SSF50447 586 668 1.41E-23 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MCR_1768 08655033365fda61bec40feb99c7826c 912 Pfam PF00009 Elongation factor Tu GTP binding domain 418 572 1.1E-33 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1768 08655033365fda61bec40feb99c7826c 912 Gene3D G3DSA:3.40.50.10050 708 814 1.6E-36 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 Gene3D G3DSA:3.30.420.40 195 392 2.1E-71 T 14-10-2018 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 PIRSF PIRSF000722 4 393 2.8E-132 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 TIGRFAM TIGR00016 ackA: acetate kinase 7 388 7.9E-132 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 SUPERFAMILY SSF53067 7 190 5.76E-60 T 14-10-2018 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 Gene3D G3DSA:3.30.420.40 5 190 4.9E-65 T 14-10-2018 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 Pfam PF00871 Acetokinase family 8 385 2.1E-129 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 7 18 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 SUPERFAMILY SSF53067 152 392 1.51E-77 T 14-10-2018 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 PRINTS PR00471 Acetate kinase family signature 7 18 9.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 PRINTS PR00471 Acetate kinase family signature 317 333 9.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 PRINTS PR00471 Acetate kinase family signature 198 219 9.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 PRINTS PR00471 Acetate kinase family signature 373 385 9.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 PRINTS PR00471 Acetate kinase family signature 169 182 9.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 PRINTS PR00471 Acetate kinase family signature 295 308 9.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MCR_1481 ffadd66e9c1061e416fe72aaf6389a71 394 Hamap MF_00020 Acetate kinase [ackA]. 1 394 161.26 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 SUPERFAMILY SSF52922 551 694 4.84E-21 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 Gene3D G3DSA:3.40.50.920 568 696 1.2E-30 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 SUPERFAMILY SSF52518 26 441 5.9E-71 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 ProSitePatterns PS00802 Transketolase signature 2. 486 502 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 29 235 1.8E-88 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 280 341 2.6E-12 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 SMART SM00861 379 544 2.2E-59 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 Pfam PF02780 Transketolase, C-terminal domain 571 687 3.0E-19 T 14-10-2018 IPR033248 Transketolase, C-terminal domain MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 Pfam PF02779 Transketolase, pyrimidine binding domain 380 539 9.9E-35 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 Gene3D G3DSA:3.40.50.970 377 550 6.8E-62 T 14-10-2018 MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 SUPERFAMILY SSF52518 378 564 7.15E-52 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 28 696 40.626 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MCR_1411 b1b5ad5d943277348ee7f955e825e923 698 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 269 694 4.8E-141 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MCR_0035 3e43881abd9956c5ce6ad5203a6afff2 167 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 1 165 19.065 T 14-10-2018 IPR022920 Disulphide bond formation protein DsbB MCR_0035 3e43881abd9956c5ce6ad5203a6afff2 167 Gene3D G3DSA:1.20.1550.10 1 167 5.4E-44 T 14-10-2018 IPR023380 DsbB-like superfamily MCR_0035 3e43881abd9956c5ce6ad5203a6afff2 167 Pfam PF02600 Disulfide bond formation protein DsbB 5 157 2.6E-36 T 14-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 MCR_0035 3e43881abd9956c5ce6ad5203a6afff2 167 SUPERFAMILY SSF158442 9 159 2.75E-34 T 14-10-2018 IPR023380 DsbB-like superfamily MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 ProSitePatterns PS00450 Aconitase family signature 1. 345 361 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 SUPERFAMILY SSF53732 2 472 3.14E-159 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 Gene3D G3DSA:3.30.499.10 334 472 2.0E-47 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 Pfam PF00330 Aconitase family (aconitate hydratase) 8 464 1.3E-154 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 PRINTS PR00415 Aconitase family signature 349 360 5.7E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 PRINTS PR00415 Aconitase family signature 201 214 5.7E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 PRINTS PR00415 Aconitase family signature 88 101 5.7E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 PRINTS PR00415 Aconitase family signature 114 122 5.7E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 PRINTS PR00415 Aconitase family signature 292 306 5.7E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 PRINTS PR00415 Aconitase family signature 139 154 5.7E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 PRINTS PR00415 Aconitase family signature 406 419 5.7E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 PRINTS PR00415 Aconitase family signature 125 138 5.7E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 PRINTS PR00415 Aconitase family signature 215 228 5.7E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 Gene3D G3DSA:3.30.499.20 5 292 5.8E-92 T 14-10-2018 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 472 57.607 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 ProSitePatterns PS01244 Aconitase family signature 2. 406 419 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MCR_1025 a3799e1f6d24673970683b0c1f71b6e5 472 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 472 1.3E-223 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MCR_1122 e18a7d877ef48cac5a57b457f6b35aeb 89 SUPERFAMILY SSF140931 10 82 2.35E-6 T 14-10-2018 IPR036597 Fido-like domain superfamily MCR_1122 e18a7d877ef48cac5a57b457f6b35aeb 89 Gene3D G3DSA:1.10.3290.10 3 87 2.8E-6 T 14-10-2018 IPR036597 Fido-like domain superfamily MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 10 626 41.921 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 Gene3D G3DSA:1.10.10.1800 464 552 7.9E-22 T 14-10-2018 MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 12 623 7.9E-275 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 Gene3D G3DSA:1.10.150.570 572 625 3.6E-23 T 14-10-2018 MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 278 292 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 Pfam PF01134 Glucose inhibited division protein A 13 402 1.5E-164 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 Pfam PF13932 GidA associated domain 406 617 1.3E-77 T 14-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 SUPERFAMILY SSF51905 11 266 9.18E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 373 396 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 SMART SM01228 548 619 4.4E-45 T 14-10-2018 MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 4.9E-6 T 14-10-2018 MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 4.9E-6 T 14-10-2018 MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 Gene3D G3DSA:3.50.50.60 5 235 1.3E-86 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1350 e4c8e0b665bd1ecd55d65f47808e877c 632 Gene3D G3DSA:3.50.50.60 301 463 2.4E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1833 a81797da91b6426162596adde63507ff 280 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 23 60 2.0E-7 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MCR_1833 a81797da91b6426162596adde63507ff 280 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 277 7.9E-97 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MCR_1833 a81797da91b6426162596adde63507ff 280 Hamap MF_00158 Pantothenate synthetase [panC]. 2 277 37.569 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MCR_1833 a81797da91b6426162596adde63507ff 280 Gene3D G3DSA:3.40.50.620 1 176 1.1E-71 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_1833 a81797da91b6426162596adde63507ff 280 Gene3D G3DSA:3.30.1300.10 177 280 3.4E-25 T 14-10-2018 MCR_1833 a81797da91b6426162596adde63507ff 280 Pfam PF02569 Pantoate-beta-alanine ligase 3 275 2.8E-99 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MCR_1833 a81797da91b6426162596adde63507ff 280 SUPERFAMILY SSF52374 1 278 8.04E-96 T 14-10-2018 MCR_1524 ef83bc308ec06e1308dbb8a5ef4c62ec 263 SUPERFAMILY SSF55920 8 256 4.45E-82 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like MCR_1524 ef83bc308ec06e1308dbb8a5ef4c62ec 263 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 170 188 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MCR_1524 ef83bc308ec06e1308dbb8a5ef4c62ec 263 Gene3D G3DSA:3.90.230.10 1 262 3.0E-103 T 14-10-2018 MCR_1524 ef83bc308ec06e1308dbb8a5ef4c62ec 263 Hamap MF_01974 Methionine aminopeptidase [map]. 6 253 39.383 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MCR_1524 ef83bc308ec06e1308dbb8a5ef4c62ec 263 Pfam PF00557 Metallopeptidase family M24 15 244 6.6E-49 T 14-10-2018 IPR000994 Peptidase M24 MCR_1524 ef83bc308ec06e1308dbb8a5ef4c62ec 263 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 7 252 2.3E-98 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MCR_1524 ef83bc308ec06e1308dbb8a5ef4c62ec 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 94 110 3.9E-22 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MCR_1524 ef83bc308ec06e1308dbb8a5ef4c62ec 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 195 207 3.9E-22 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MCR_1524 ef83bc308ec06e1308dbb8a5ef4c62ec 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 71 84 3.9E-22 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MCR_1524 ef83bc308ec06e1308dbb8a5ef4c62ec 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 164 176 3.9E-22 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MCR_1080 45e42ef90aa8a71951dede28ac6398d0 171 Gene3D G3DSA:3.30.1130.10 34 166 1.7E-57 T 14-10-2018 MCR_1080 45e42ef90aa8a71951dede28ac6398d0 171 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 91 101 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MCR_1080 45e42ef90aa8a71951dede28ac6398d0 171 Pfam PF01227 GTP cyclohydrolase I 2 162 2.7E-66 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MCR_1080 45e42ef90aa8a71951dede28ac6398d0 171 SUPERFAMILY SSF55620 2 164 8.89E-68 T 14-10-2018 MCR_1080 45e42ef90aa8a71951dede28ac6398d0 171 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 43 59 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MCR_1080 45e42ef90aa8a71951dede28ac6398d0 171 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 2 163 7.0E-66 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MCR_1080 45e42ef90aa8a71951dede28ac6398d0 171 Gene3D G3DSA:1.10.286.10 1 32 5.0E-10 T 14-10-2018 MCR_1080 45e42ef90aa8a71951dede28ac6398d0 171 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 1 164 29.825 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MCR_0884 51c2973996673a7d4f3e9ff115d4a75d 210 SUPERFAMILY SSF56529 13 202 2.75E-47 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MCR_0884 51c2973996673a7d4f3e9ff115d4a75d 210 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 16 200 4.3E-35 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MCR_0884 51c2973996673a7d4f3e9ff115d4a75d 210 Gene3D G3DSA:3.90.850.10 9 209 2.4E-54 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MCR_1773 d184dd4ada31ad052b909868210abdcd 365 Pfam PF00953 Glycosyl transferase family 4 93 289 8.7E-29 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 MCR_1773 d184dd4ada31ad052b909868210abdcd 365 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 62 74 6.1E-6 T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_1773 d184dd4ada31ad052b909868210abdcd 365 ProSitePatterns PS01347 MraY family signature 1. 62 74 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_1773 d184dd4ada31ad052b909868210abdcd 365 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 19 363 22.638 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_1773 d184dd4ada31ad052b909868210abdcd 365 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 35 365 2.7E-119 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_1773 d184dd4ada31ad052b909868210abdcd 365 ProSitePatterns PS01348 MraY family signature 2. 194 205 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_1615 fa71cf3d40bd69f1c012ecd8f1bace2f 516 Pfam PF02541 Ppx/GppA phosphatase family 47 325 7.1E-76 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MCR_1615 fa71cf3d40bd69f1c012ecd8f1bace2f 516 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 30 323 2.0E-94 T 14-10-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 MCR_1615 fa71cf3d40bd69f1c012ecd8f1bace2f 516 SUPERFAMILY SSF53067 154 326 3.59E-45 T 14-10-2018 MCR_1615 fa71cf3d40bd69f1c012ecd8f1bace2f 516 Gene3D G3DSA:1.10.3210.10 327 515 5.4E-43 T 14-10-2018 MCR_1615 fa71cf3d40bd69f1c012ecd8f1bace2f 516 Gene3D G3DSA:3.30.420.150 134 312 2.2E-86 T 14-10-2018 MCR_1615 fa71cf3d40bd69f1c012ecd8f1bace2f 516 SUPERFAMILY SSF109604 330 513 1.15E-34 T 14-10-2018 MCR_1615 fa71cf3d40bd69f1c012ecd8f1bace2f 516 PIRSF PIRSF001267 20 516 6.9E-172 T 14-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 MCR_1615 fa71cf3d40bd69f1c012ecd8f1bace2f 516 SUPERFAMILY SSF53067 29 148 4.64E-35 T 14-10-2018 MCR_1615 fa71cf3d40bd69f1c012ecd8f1bace2f 516 Gene3D G3DSA:3.30.420.40 32 320 2.2E-86 T 14-10-2018 MCR_1846 ecd91f8c76f5e15846af68cad9729fc9 442 Gene3D G3DSA:3.40.47.10 287 429 3.1E-50 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_1846 ecd91f8c76f5e15846af68cad9729fc9 442 SMART SM00825 Beta-ketoacyl synthase 23 442 1.6E-16 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MCR_1846 ecd91f8c76f5e15846af68cad9729fc9 442 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 21 277 2.6E-55 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MCR_1846 ecd91f8c76f5e15846af68cad9729fc9 442 SUPERFAMILY SSF53901 22 282 1.5E-74 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_1846 ecd91f8c76f5e15846af68cad9729fc9 442 PIRSF PIRSF000447 18 442 2.0E-170 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MCR_1846 ecd91f8c76f5e15846af68cad9729fc9 442 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 22 438 7.9E-173 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MCR_1846 ecd91f8c76f5e15846af68cad9729fc9 442 Gene3D G3DSA:3.40.47.10 6 285 7.7E-85 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_1846 ecd91f8c76f5e15846af68cad9729fc9 442 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 285 396 1.8E-36 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MCR_1846 ecd91f8c76f5e15846af68cad9729fc9 442 SUPERFAMILY SSF53901 245 440 2.04E-70 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_1394 aa61f66c2fd24e1c02851e512802c188 103 Pfam PF03658 RnfH family Ubiquitin 9 98 4.9E-17 T 14-10-2018 IPR005346 RnfH protein MCR_1394 aa61f66c2fd24e1c02851e512802c188 103 SUPERFAMILY SSF54285 9 90 7.06E-11 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MCR_1394 aa61f66c2fd24e1c02851e512802c188 103 Gene3D G3DSA:3.10.20.280 1 99 1.3E-17 T 14-10-2018 IPR037021 RnfH superfamily MCR_0142 3175aa4a7049d665bfed0691791fdafd 98 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 2 98 27.028 T 14-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 MCR_0142 3175aa4a7049d665bfed0691791fdafd 98 PRINTS PR01727 Prokaryotic integration host factor signature 61 74 1.4E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0142 3175aa4a7049d665bfed0691791fdafd 98 PRINTS PR01727 Prokaryotic integration host factor signature 77 91 1.4E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0142 3175aa4a7049d665bfed0691791fdafd 98 PRINTS PR01727 Prokaryotic integration host factor signature 43 58 1.4E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0142 3175aa4a7049d665bfed0691791fdafd 98 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 49 68 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MCR_0142 3175aa4a7049d665bfed0691791fdafd 98 SUPERFAMILY SSF47729 4 94 6.04E-29 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MCR_0142 3175aa4a7049d665bfed0691791fdafd 98 Pfam PF00216 Bacterial DNA-binding protein 4 89 4.0E-29 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0142 3175aa4a7049d665bfed0691791fdafd 98 Gene3D G3DSA:4.10.520.10 2 97 7.8E-33 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MCR_0142 3175aa4a7049d665bfed0691791fdafd 98 SMART SM00411 4 93 8.6E-36 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0446 3f255e96b4d7a71675e7a267750a0b0f 284 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 8 216 1.6E-42 T 14-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain MCR_0477 a354424d683c58d94263021d6155b5d0 222 Gene3D G3DSA:2.60.60.30 25 199 1.3E-15 T 14-10-2018 MCR_0477 a354424d683c58d94263021d6155b5d0 222 Pfam PF02342 TerD domain 36 154 1.6E-12 T 14-10-2018 IPR003325 TerD domain MCR_0899 f27c3ad52a3a9b18fa84265e173d0f2d 103 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 75 9.9E-9 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MCR_0899 f27c3ad52a3a9b18fa84265e173d0f2d 103 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 35 43 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MCR_0899 f27c3ad52a3a9b18fa84265e173d0f2d 103 Gene3D G3DSA:3.10.20.30 3 93 6.0E-12 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MCR_0899 f27c3ad52a3a9b18fa84265e173d0f2d 103 SUPERFAMILY SSF54292 5 86 3.15E-14 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MCR_0096 d5def98a7adee186602032c1487a179e 307 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 31 260 1.1E-44 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 MCR_0096 d5def98a7adee186602032c1487a179e 307 PIRSF PIRSF002936 2 307 8.0E-134 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MCR_0096 d5def98a7adee186602032c1487a179e 307 SUPERFAMILY SSF52402 9 214 3.31E-61 T 14-10-2018 MCR_0096 d5def98a7adee186602032c1487a179e 307 Gene3D G3DSA:3.40.50.620 9 217 8.7E-53 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0632 0a05035f32019286e189fb71c152c15b 168 Gene3D G3DSA:3.40.50.2020 1 167 1.5E-43 T 14-10-2018 MCR_0632 0a05035f32019286e189fb71c152c15b 168 Pfam PF00156 Phosphoribosyl transferase domain 35 150 6.0E-15 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MCR_0632 0a05035f32019286e189fb71c152c15b 168 SUPERFAMILY SSF53271 3 160 1.08E-33 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MCR_0999 212758bf8cdb298b530d60373db8edc0 239 Pfam PF00005 ABC transporter 20 164 2.5E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0999 212758bf8cdb298b530d60373db8edc0 239 Gene3D G3DSA:3.40.50.300 1 238 1.1E-76 T 14-10-2018 MCR_0999 212758bf8cdb298b530d60373db8edc0 239 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0999 212758bf8cdb298b530d60373db8edc0 239 SMART SM00382 27 214 1.5E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0999 212758bf8cdb298b530d60373db8edc0 239 SUPERFAMILY SSF52540 3 238 2.6E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1586 a5a8fb81e1ee1ca75b908ca80eb6badc 52 SMART SM01403 1 50 0.001 T 14-10-2018 IPR027486 Ribosomal protein S10 domain MCR_1586 a5a8fb81e1ee1ca75b908ca80eb6badc 52 Pfam PF00338 Ribosomal protein S10p/S20e 1 49 4.1E-16 T 14-10-2018 IPR027486 Ribosomal protein S10 domain MCR_1586 a5a8fb81e1ee1ca75b908ca80eb6badc 52 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 1 50 3.5E-21 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1586 a5a8fb81e1ee1ca75b908ca80eb6badc 52 Gene3D G3DSA:3.30.70.600 1 52 6.9E-18 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily MCR_1586 a5a8fb81e1ee1ca75b908ca80eb6badc 52 SUPERFAMILY SSF54999 2 50 1.7E-17 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily MCR_1595 b3e08694425c81eee2e279faae4ee1d3 224 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 163 180 1.4E-9 T 14-10-2018 MCR_1595 b3e08694425c81eee2e279faae4ee1d3 224 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 181 200 1.4E-9 T 14-10-2018 MCR_1595 b3e08694425c81eee2e279faae4ee1d3 224 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 201 221 1.4E-9 T 14-10-2018 MCR_1595 b3e08694425c81eee2e279faae4ee1d3 224 PRINTS PR01021 OMPA domain signature 118 140 1.1E-12 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MCR_1595 b3e08694425c81eee2e279faae4ee1d3 224 PRINTS PR01021 OMPA domain signature 148 163 1.1E-12 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MCR_1595 b3e08694425c81eee2e279faae4ee1d3 224 PRINTS PR01021 OMPA domain signature 163 179 1.1E-12 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MCR_1595 b3e08694425c81eee2e279faae4ee1d3 224 Pfam PF00691 OmpA family 117 212 2.8E-24 T 14-10-2018 IPR006665 OmpA-like domain MCR_1595 b3e08694425c81eee2e279faae4ee1d3 224 SUPERFAMILY SSF103088 106 218 1.96E-40 T 14-10-2018 IPR036737 OmpA-like domain superfamily MCR_1595 b3e08694425c81eee2e279faae4ee1d3 224 Pfam PF05433 Glycine zipper 2TM domain 41 82 1.2E-5 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 MCR_1595 b3e08694425c81eee2e279faae4ee1d3 224 Gene3D G3DSA:3.30.1330.60 79 222 3.2E-48 T 14-10-2018 IPR036737 OmpA-like domain superfamily MCR_1595 b3e08694425c81eee2e279faae4ee1d3 224 ProSitePatterns PS01068 OmpA-like domain. 150 194 - T 14-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 Pfam PF07724 AAA domain (Cdc48 subfamily) 595 757 3.6E-57 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 Gene3D G3DSA:3.40.50.300 146 339 1.0E-73 T 14-10-2018 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 SUPERFAMILY SSF52540 156 543 1.26E-95 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 Gene3D G3DSA:3.40.50.300 340 542 1.4E-65 T 14-10-2018 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 Gene3D G3DSA:1.10.8.60 763 856 3.7E-27 T 14-10-2018 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 706 720 1.8E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 673 691 1.8E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 599 617 1.8E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 644 662 1.8E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 SUPERFAMILY SSF81923 4 152 6.08E-29 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 Gene3D G3DSA:1.10.1780.10 1 145 6.7E-22 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 629 647 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 200 332 6.0E-12 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 Gene3D G3DSA:3.40.50.300 548 761 1.1E-87 T 14-10-2018 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 763 842 1.7E-26 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 852 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 SMART SM00382 595 755 2.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 SMART SM00382 195 341 2.0E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 SUPERFAMILY SSF52540 544 850 6.91E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 291 303 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 SMART SM01086 763 852 3.0E-35 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 66 9.5E-7 T 14-10-2018 IPR004176 Clp, N-terminal MCR_1362 ef5c7beafe70a0999032c9f2a04d358a 858 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 142 0.25 T 14-10-2018 IPR004176 Clp, N-terminal MCR_0398 6e36c71a0680db2319591caa6f6d6394 442 Hamap MF_00372 Imidazolonepropionase [hutI]. 16 437 40.968 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_0398 6e36c71a0680db2319591caa6f6d6394 442 Gene3D G3DSA:2.30.40.10 47 433 3.7E-156 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MCR_0398 6e36c71a0680db2319591caa6f6d6394 442 Pfam PF01979 Amidohydrolase family 92 435 3.5E-23 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MCR_0398 6e36c71a0680db2319591caa6f6d6394 442 SUPERFAMILY SSF51338 15 436 5.26E-26 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MCR_0398 6e36c71a0680db2319591caa6f6d6394 442 SUPERFAMILY SSF51556 94 397 1.04E-82 T 14-10-2018 IPR032466 Metal-dependent hydrolase MCR_0398 6e36c71a0680db2319591caa6f6d6394 442 TIGRFAM TIGR01224 hutI: imidazolonepropionase 57 436 4.1E-137 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_0398 6e36c71a0680db2319591caa6f6d6394 442 Gene3D G3DSA:3.20.20.140 95 397 3.7E-156 T 14-10-2018 MCR_0878 e3e533d1bf1a21ecc1e5618261197adc 283 SUPERFAMILY SSF55811 102 273 5.28E-36 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MCR_0878 e3e533d1bf1a21ecc1e5618261197adc 283 ProSitePatterns PS00893 Nudix box signature. 191 212 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MCR_0878 e3e533d1bf1a21ecc1e5618261197adc 283 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 119 150 1.3E-8 T 14-10-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 MCR_0878 e3e533d1bf1a21ecc1e5618261197adc 283 Gene3D G3DSA:3.90.79.10 152 283 2.5E-34 T 14-10-2018 MCR_0878 e3e533d1bf1a21ecc1e5618261197adc 283 Gene3D G3DSA:3.90.79.20 32 151 7.8E-17 T 14-10-2018 MCR_0878 e3e533d1bf1a21ecc1e5618261197adc 283 Pfam PF00293 NUDIX domain 170 265 2.1E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MCR_0044 2d9d206159cdd140a085678395f083cf 649 SMART SM00382 26 221 4.0E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0044 2d9d206159cdd140a085678395f083cf 649 SMART SM00382 336 505 9.5E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0044 2d9d206159cdd140a085678395f083cf 649 Pfam PF00005 ABC transporter 18 177 8.0E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0044 2d9d206159cdd140a085678395f083cf 649 Gene3D G3DSA:3.40.50.300 3 274 5.9E-57 T 14-10-2018 MCR_0044 2d9d206159cdd140a085678395f083cf 649 Pfam PF00005 ABC transporter 327 458 4.1E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0044 2d9d206159cdd140a085678395f083cf 649 Gene3D G3DSA:3.40.50.300 275 539 1.2E-52 T 14-10-2018 MCR_0044 2d9d206159cdd140a085678395f083cf 649 Pfam PF12848 ABC transporter 216 291 5.7E-29 T 14-10-2018 IPR032781 ABC-transporter extension domain MCR_0044 2d9d206159cdd140a085678395f083cf 649 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0044 2d9d206159cdd140a085678395f083cf 649 SUPERFAMILY SSF52540 297 508 9.5E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0044 2d9d206159cdd140a085678395f083cf 649 SUPERFAMILY SSF52540 2 237 5.48E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0044 2d9d206159cdd140a085678395f083cf 649 ProSitePatterns PS00211 ABC transporters family signature. 430 444 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1879 4fd28f38a9ba93689a2a4a92aec9ca71 46 SUPERFAMILY SSF54506 11 43 6.43E-6 T 14-10-2018 MCR_1879 4fd28f38a9ba93689a2a4a92aec9ca71 46 Gene3D G3DSA:3.10.310.10 21 43 7.3E-6 T 14-10-2018 MCR_1879 4fd28f38a9ba93689a2a4a92aec9ca71 46 Pfam PF04303 PrpF protein 21 43 1.4E-4 T 14-10-2018 IPR007400 PrpF protein MCR_1196 d013c555622055957c0f8246458f829e 299 Pfam PF06738 Putative threonine/serine exporter 41 291 1.0E-49 T 14-10-2018 IPR010619 Putative threonine/serine exporter MCR_1193 b91e0c2d903f6d2a218af5010271cacd 497 Pfam PF11840 Protein of unknown function (DUF3360) 10 492 2.0E-268 T 14-10-2018 IPR021794 Protein of unknown function DUF3360 MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 Pfam PF00676 Dehydrogenase E1 component 214 518 3.5E-52 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 Gene3D G3DSA:3.40.50.12470 563 809 1.6E-162 T 14-10-2018 MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 SUPERFAMILY SSF52518 583 800 1.08E-47 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 18 942 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 Gene3D G3DSA:3.40.50.11610 730 940 1.6E-162 T 14-10-2018 MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 PIRSF PIRSF000157 1 945 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 Gene3D G3DSA:3.40.50.970 167 526 5.5E-139 T 14-10-2018 MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 SMART SM00861 600 793 8.4E-62 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 797 943 5.1E-47 T 14-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 16 50 8.5E-11 T 14-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 Gene3D G3DSA:1.10.287.1150 84 166 5.0E-26 T 14-10-2018 MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 Pfam PF02779 Transketolase, pyrimidine binding domain 599 794 2.6E-63 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MCR_0071 580d2d35a0d664ed7817e05e25656ad0 951 SUPERFAMILY SSF52518 122 530 9.57E-83 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 Gene3D G3DSA:3.40.50.720 16 357 2.0E-119 T 14-10-2018 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 16 132 5.8E-27 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 SMART SM00846 15 182 5.3E-57 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 Gene3D G3DSA:3.30.360.10 185 350 2.0E-119 T 14-10-2018 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 187 342 3.4E-51 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 PIRSF PIRSF000149 13 363 4.9E-107 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 194 7.6E-28 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 259 276 7.6E-28 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 139 152 7.6E-28 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 203 219 7.6E-28 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 299 314 7.6E-28 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 SUPERFAMILY SSF55347 182 343 4.17E-55 T 14-10-2018 MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 SUPERFAMILY SSF51735 15 210 1.05E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0663 2c7f4f06cff73f039adcf1fc6b42e815 363 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 180 187 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1378 857e0f1cfc811b9531ff3b80d7469215 192 Gene3D G3DSA:3.90.470.20 95 189 1.4E-6 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MCR_1378 857e0f1cfc811b9531ff3b80d7469215 192 SUPERFAMILY SSF56214 96 151 6.15E-7 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MCR_1378 857e0f1cfc811b9531ff3b80d7469215 192 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 95 182 1.1E-6 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MCR_0543 531940208ada98143f6c7daab04d7c3f 414 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 149 242 2.2E-36 T 14-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MCR_0543 531940208ada98143f6c7daab04d7c3f 414 SUPERFAMILY SSF55347 129 277 1.83E-60 T 14-10-2018 MCR_0543 531940208ada98143f6c7daab04d7c3f 414 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7 402 9.0E-137 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MCR_0543 531940208ada98143f6c7daab04d7c3f 414 PIRSF PIRSF006205 5 410 4.7E-139 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MCR_0543 531940208ada98143f6c7daab04d7c3f 414 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 8 404 42.83 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MCR_0543 531940208ada98143f6c7daab04d7c3f 414 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 8 135 6.9E-40 T 14-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MCR_0543 531940208ada98143f6c7daab04d7c3f 414 Pfam PF13288 DXP reductoisomerase C-terminal domain 274 399 2.7E-36 T 14-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MCR_0543 531940208ada98143f6c7daab04d7c3f 414 SUPERFAMILY SSF51735 6 153 5.23E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0543 531940208ada98143f6c7daab04d7c3f 414 Gene3D G3DSA:3.40.50.720 4 153 7.6E-54 T 14-10-2018 MCR_0543 531940208ada98143f6c7daab04d7c3f 414 Gene3D G3DSA:1.10.1740.10 315 414 7.1E-41 T 14-10-2018 MCR_0543 531940208ada98143f6c7daab04d7c3f 414 SUPERFAMILY SSF69055 304 404 1.1E-19 T 14-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MCR_0584 90e666d12c22638b3359b8668baf89bd 427 Pfam PF01842 ACT domain 277 335 2.2E-8 T 14-10-2018 IPR002912 ACT domain MCR_0584 90e666d12c22638b3359b8668baf89bd 427 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 415 1.5E-128 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MCR_0584 90e666d12c22638b3359b8668baf89bd 427 Gene3D G3DSA:3.40.1160.10 1 257 1.5E-87 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MCR_0584 90e666d12c22638b3359b8668baf89bd 427 SUPERFAMILY SSF55021 260 339 1.31E-19 T 14-10-2018 MCR_0584 90e666d12c22638b3359b8668baf89bd 427 Pfam PF00696 Amino acid kinase family 3 229 3.8E-50 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MCR_0584 90e666d12c22638b3359b8668baf89bd 427 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 415 9.2E-129 T 14-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MCR_0584 90e666d12c22638b3359b8668baf89bd 427 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 14-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MCR_0584 90e666d12c22638b3359b8668baf89bd 427 PIRSF PIRSF000726 1 60 6.0E-21 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MCR_0584 90e666d12c22638b3359b8668baf89bd 427 PIRSF PIRSF000726 55 423 3.5E-134 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MCR_0584 90e666d12c22638b3359b8668baf89bd 427 Pfam PF13840 ACT domain 351 411 2.6E-14 T 14-10-2018 IPR027795 CASTOR, ACT domain MCR_0584 90e666d12c22638b3359b8668baf89bd 427 Gene3D G3DSA:3.30.2130.10 258 427 2.7E-57 T 14-10-2018 MCR_0584 90e666d12c22638b3359b8668baf89bd 427 SUPERFAMILY SSF55021 341 418 8.51E-24 T 14-10-2018 MCR_0584 90e666d12c22638b3359b8668baf89bd 427 SUPERFAMILY SSF53633 4 255 8.77E-76 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MCR_1302 801c2e06f9242a9bc88842361e5e3575 118 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 30 71 1.4E-5 T 14-10-2018 IPR018660 C-type lysozyme inhibitor MCR_1302 801c2e06f9242a9bc88842361e5e3575 118 Gene3D G3DSA:2.40.128.200 22 77 8.1E-6 T 14-10-2018 IPR036328 C-type lysozyme inhibitor superfamily MCR_1681 61732d68089ec3166a75aa3992332e16 528 Pfam PF16658 Class II release factor RF3, C-terminal domain 386 513 1.3E-45 T 14-10-2018 IPR032090 Peptide chain release factor 3, C-terminal MCR_1681 61732d68089ec3166a75aa3992332e16 528 Gene3D G3DSA:3.30.70.3280 389 528 2.4E-51 T 14-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily MCR_1681 61732d68089ec3166a75aa3992332e16 528 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 5 528 9.2E-244 T 14-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MCR_1681 61732d68089ec3166a75aa3992332e16 528 Pfam PF03144 Elongation factor Tu domain 2 313 378 5.8E-9 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MCR_1681 61732d68089ec3166a75aa3992332e16 528 SUPERFAMILY SSF54980 392 467 4.68E-18 T 14-10-2018 IPR035647 EF-G domain III/V-like MCR_1681 61732d68089ec3166a75aa3992332e16 528 SUPERFAMILY SSF50447 261 392 6.63E-28 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MCR_1681 61732d68089ec3166a75aa3992332e16 528 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MCR_1681 61732d68089ec3166a75aa3992332e16 528 SUPERFAMILY SSF52540 8 276 2.09E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1681 61732d68089ec3166a75aa3992332e16 528 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 3 526 50.325 T 14-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MCR_1681 61732d68089ec3166a75aa3992332e16 528 Pfam PF00009 Elongation factor Tu GTP binding domain 12 276 1.2E-47 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1681 61732d68089ec3166a75aa3992332e16 528 PRINTS PR00315 GTP-binding elongation factor signature 100 111 2.3E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1681 61732d68089ec3166a75aa3992332e16 528 PRINTS PR00315 GTP-binding elongation factor signature 84 94 2.3E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1681 61732d68089ec3166a75aa3992332e16 528 PRINTS PR00315 GTP-binding elongation factor signature 64 72 2.3E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1681 61732d68089ec3166a75aa3992332e16 528 PRINTS PR00315 GTP-binding elongation factor signature 136 145 2.3E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1681 61732d68089ec3166a75aa3992332e16 528 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1681 61732d68089ec3166a75aa3992332e16 528 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 147 1.2E-18 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MCR_1681 61732d68089ec3166a75aa3992332e16 528 Gene3D G3DSA:3.40.50.300 71 378 3.3E-107 T 14-10-2018 MCR_1681 61732d68089ec3166a75aa3992332e16 528 Gene3D G3DSA:3.40.50.300 109 274 3.3E-107 T 14-10-2018 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 Pfam PF04545 Sigma-70, region 4 309 360 7.5E-16 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 Pfam PF00140 Sigma-70 factor, region 1.2 99 123 2.5E-5 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 SUPERFAMILY SSF88659 270 362 1.25E-18 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 PRINTS PR00046 Major sigma-70 factor signature 347 358 2.3E-17 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 PRINTS PR00046 Major sigma-70 factor signature 332 347 2.3E-17 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 PRINTS PR00046 Major sigma-70 factor signature 313 325 2.3E-17 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 PRINTS PR00046 Major sigma-70 factor signature 160 173 2.3E-17 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 84 364 52.069 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 98 363 1.0E-119 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 Gene3D G3DSA:1.20.140.160 216 364 8.5E-15 T 14-10-2018 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 Gene3D G3DSA:1.20.120.1810 97 205 9.8E-28 T 14-10-2018 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 131 361 2.7E-31 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 SUPERFAMILY SSF88946 99 205 1.07E-39 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 Pfam PF04542 Sigma-70 region 2 136 205 4.5E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 160 173 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0531 feba57ef0a39a78057d1aef2fb51ae8b 371 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 332 358 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 Gene3D G3DSA:3.90.800.10 101 209 9.2E-101 T 14-10-2018 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 Gene3D G3DSA:3.40.50.620 28 247 9.2E-101 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 Gene3D G3DSA:2.40.240.10 342 579 8.6E-59 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 PRINTS PR00987 Glutamyl-tRNA synthetase signature 60 73 6.1E-8 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 PRINTS PR00987 Glutamyl-tRNA synthetase signature 31 43 6.1E-8 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 6.1E-8 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 SUPERFAMILY SSF52374 28 346 1.72E-94 T 14-10-2018 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 Gene3D G3DSA:1.10.1160.10 261 339 2.8E-31 T 14-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 341 561 2.2E-42 T 14-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 SUPERFAMILY SSF50715 342 581 1.05E-49 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 Gene3D G3DSA:2.40.240.10 348 483 8.6E-59 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 29 582 1.3E-201 T 14-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_0661 0970f4683c9e230a6b564574dbd1e3a8 585 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 324 6.5E-106 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 MCR_0855 cca1e3db6e9516e51c223f8fb77531ca 347 PIRSF PIRSF026649 33 344 4.7E-72 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MCR_0855 cca1e3db6e9516e51c223f8fb77531ca 347 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 36 337 1.7E-60 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MCR_0635 158ffa474601a80333fcdc971370e847 285 SUPERFAMILY SSF53335 51 280 4.49E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0635 158ffa474601a80333fcdc971370e847 285 Pfam PF01209 ubiE/COQ5 methyltransferase family 52 282 1.4E-99 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MCR_0635 158ffa474601a80333fcdc971370e847 285 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 48 282 38.8 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MCR_0635 158ffa474601a80333fcdc971370e847 285 Gene3D G3DSA:3.40.50.150 63 283 5.3E-77 T 14-10-2018 MCR_0635 158ffa474601a80333fcdc971370e847 285 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 57 282 2.0E-83 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MCR_0635 158ffa474601a80333fcdc971370e847 285 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 68 83 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MCR_0635 158ffa474601a80333fcdc971370e847 285 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 190 204 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MCR_1247 d9b6d672d3aed6d2ed8f56a79c755d52 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 1.7E-7 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MCR_1247 d9b6d672d3aed6d2ed8f56a79c755d52 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 182 194 1.7E-7 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MCR_1247 d9b6d672d3aed6d2ed8f56a79c755d52 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 57 68 1.7E-7 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MCR_1247 d9b6d672d3aed6d2ed8f56a79c755d52 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 152 163 1.7E-7 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MCR_1247 d9b6d672d3aed6d2ed8f56a79c755d52 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 294 311 1.7E-7 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MCR_1247 d9b6d672d3aed6d2ed8f56a79c755d52 358 SUPERFAMILY SSF56935 15 358 4.58E-43 T 14-10-2018 MCR_1247 d9b6d672d3aed6d2ed8f56a79c755d52 358 Gene3D G3DSA:2.40.160.10 8 358 6.6E-48 T 14-10-2018 IPR023614 Porin domain superfamily MCR_1247 d9b6d672d3aed6d2ed8f56a79c755d52 358 PRINTS PR00184 Neisseria sp. porin signature 59 84 2.2E-5 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MCR_1247 d9b6d672d3aed6d2ed8f56a79c755d52 358 PRINTS PR00184 Neisseria sp. porin signature 151 168 2.2E-5 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MCR_1247 d9b6d672d3aed6d2ed8f56a79c755d52 358 PRINTS PR00184 Neisseria sp. porin signature 291 315 2.2E-5 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MCR_1247 d9b6d672d3aed6d2ed8f56a79c755d52 358 Pfam PF13609 Gram-negative porin 7 318 3.0E-33 T 14-10-2018 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 SMART SM00962 100 296 9.2E-111 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 SMART SM00382 99 277 1.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 Pfam PF02978 Signal peptide binding domain 328 429 7.9E-31 T 14-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.6E-20 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 431 2.8E-174 T 14-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 Gene3D G3DSA:1.20.120.140 5 305 5.1E-122 T 14-10-2018 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 Gene3D G3DSA:3.40.50.300 90 285 5.1E-122 T 14-10-2018 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 Pfam PF00448 SRP54-type protein, GTPase domain 101 296 7.3E-73 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 442 33.836 T 14-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 SUPERFAMILY SSF52540 42 351 2.83E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 SMART SM00963 1 86 2.4E-35 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 SUPERFAMILY SSF47446 298 432 1.24E-43 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MCR_1342 bf81549f6884ebc5c2fc2606b2ca6f80 514 Gene3D G3DSA:1.10.260.30 310 448 9.0E-37 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 118 131 - T 14-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 Gene3D G3DSA:1.10.285.10 380 446 3.3E-7 T 14-10-2018 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 Gene3D G3DSA:3.40.50.720 205 368 5.6E-159 T 14-10-2018 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 231 251 1.7E-31 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 367 378 1.7E-31 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 189 211 1.7E-31 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 110 124 1.7E-31 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 Gene3D G3DSA:3.40.50.10860 51 186 5.6E-159 T 14-10-2018 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 SUPERFAMILY SSF53223 3 192 3.01E-68 T 14-10-2018 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 SUPERFAMILY SSF51735 198 445 1.58E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 SMART SM00839 200 444 6.6E-78 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 198 444 2.7E-78 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 Gene3D G3DSA:1.10.285.10 3 379 5.6E-159 T 14-10-2018 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 53 180 1.7E-50 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MCR_0442 91fe11c46f1d34bae6bfbfeabbc8a319 446 PIRSF PIRSF000185 18 446 3.1E-114 T 14-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 MCR_1749 0c8a222c349ec184c4d6a52c6cf117aa 80 Gene3D G3DSA:3.30.300.90 1 80 9.3E-22 T 14-10-2018 MCR_1749 0c8a222c349ec184c4d6a52c6cf117aa 80 SUPERFAMILY SSF82657 1 79 8.76E-24 T 14-10-2018 IPR036065 BolA-like superfamily MCR_1749 0c8a222c349ec184c4d6a52c6cf117aa 80 PIRSF PIRSF003113 1 80 3.8E-19 T 14-10-2018 IPR002634 BolA protein MCR_1749 0c8a222c349ec184c4d6a52c6cf117aa 80 Pfam PF01722 BolA-like protein 22 74 1.7E-14 T 14-10-2018 IPR002634 BolA protein MCR_1783 8f171c6c73677440773be6ca525b81fd 338 SUPERFAMILY SSF56112 10 335 1.25E-48 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MCR_1783 8f171c6c73677440773be6ca525b81fd 338 Pfam PF01636 Phosphotransferase enzyme family 33 252 3.4E-19 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase MCR_1783 8f171c6c73677440773be6ca525b81fd 338 Gene3D G3DSA:3.90.1200.10 121 337 2.0E-48 T 14-10-2018 MCR_1783 8f171c6c73677440773be6ca525b81fd 338 Hamap MF_00301 Homoserine kinase [thrB]. 1 338 60.426 T 14-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MCR_1783 8f171c6c73677440773be6ca525b81fd 338 Gene3D G3DSA:3.30.200.20 6 116 3.6E-11 T 14-10-2018 MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 6.3E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 6.3E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 6.3E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 TIGRFAM TIGR02415 23BDH: acetoin reductases 11 264 1.6E-104 T 14-10-2018 IPR014007 Acetoin reductase GO:0019152|GO:0045150|GO:0055114 KEGG: 00650+1.1.1.304|MetaCyc: PWY-6389 MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 SUPERFAMILY SSF51735 9 262 4.33E-80 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 261 1.2E-58 T 14-10-2018 MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 Gene3D G3DSA:3.40.50.720 10 264 6.7E-86 T 14-10-2018 MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1660 64d5c8bf1e78bd83eefacb81ba032484 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0031 7c6e79599d69b2e1fd8824445415294c 96 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 11 80 6.0E-19 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MCR_0031 7c6e79599d69b2e1fd8824445415294c 96 Gene3D G3DSA:1.10.3880.10 6 96 2.6E-32 T 14-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 MCR_0031 7c6e79599d69b2e1fd8824445415294c 96 SUPERFAMILY SSF111148 9 93 2.75E-33 T 14-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 MCR_0031 7c6e79599d69b2e1fd8824445415294c 96 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 7 94 21.284 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MCR_0031 7c6e79599d69b2e1fd8824445415294c 96 Pfam PF04362 Bacterial Fe(2+) trafficking 9 93 7.9E-34 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MCR_0031 7c6e79599d69b2e1fd8824445415294c 96 PIRSF PIRSF029827 8 96 2.1E-29 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MCR_0061 35d6c9a552d8090dc9b721179c084024 788 SMART SM00316 657 728 6.3E-25 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_0061 35d6c9a552d8090dc9b721179c084024 788 Gene3D G3DSA:3.30.420.140 338 464 3.5E-127 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 MCR_0061 35d6c9a552d8090dc9b721179c084024 788 SUPERFAMILY SSF47781 483 570 2.82E-26 T 14-10-2018 IPR010994 RuvA domain 2-like MCR_0061 35d6c9a552d8090dc9b721179c084024 788 SMART SM00732 339 437 7.9E-30 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MCR_0061 35d6c9a552d8090dc9b721179c084024 788 Gene3D G3DSA:1.10.10.650 11 121 1.4E-29 T 14-10-2018 IPR023319 Tex-like protein, HTH domain superfamily MCR_0061 35d6c9a552d8090dc9b721179c084024 788 Pfam PF16921 Tex protein YqgF-like domain 339 464 1.6E-52 T 14-10-2018 IPR032639 Tex protein, YqgF-like domain MCR_0061 35d6c9a552d8090dc9b721179c084024 788 Pfam PF09371 Tex-like protein N-terminal domain 22 213 3.5E-46 T 14-10-2018 IPR018974 Tex-like protein, N-terminal MCR_0061 35d6c9a552d8090dc9b721179c084024 788 Gene3D G3DSA:1.10.3500.10 126 511 3.5E-127 T 14-10-2018 IPR023323 Tex-like domain superfamily MCR_0061 35d6c9a552d8090dc9b721179c084024 788 SUPERFAMILY SSF50249 645 734 3.66E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0061 35d6c9a552d8090dc9b721179c084024 788 SUPERFAMILY SSF47781 573 640 1.89E-11 T 14-10-2018 IPR010994 RuvA domain 2-like MCR_0061 35d6c9a552d8090dc9b721179c084024 788 SUPERFAMILY SSF53098 335 482 3.57E-45 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MCR_0061 35d6c9a552d8090dc9b721179c084024 788 Pfam PF12836 Helix-hairpin-helix motif 504 568 8.9E-26 T 14-10-2018 MCR_0061 35d6c9a552d8090dc9b721179c084024 788 Gene3D G3DSA:2.40.50.140 639 732 6.5E-29 T 14-10-2018 MCR_0061 35d6c9a552d8090dc9b721179c084024 788 SUPERFAMILY SSF158832 15 334 5.75E-73 T 14-10-2018 MCR_0061 35d6c9a552d8090dc9b721179c084024 788 Gene3D G3DSA:1.10.150.310 512 638 1.6E-41 T 14-10-2018 MCR_0061 35d6c9a552d8090dc9b721179c084024 788 Pfam PF00575 S1 RNA binding domain 656 728 7.6E-17 T 14-10-2018 IPR003029 S1 domain GO:0003676 MCR_1424 3d57bad9dbd3ce5b99cdce5715641696 293 Gene3D G3DSA:3.90.226.10 37 292 7.1E-70 T 14-10-2018 MCR_1424 3d57bad9dbd3ce5b99cdce5715641696 293 Pfam PF01039 Carboxyl transferase domain 106 252 2.3E-13 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 MCR_1424 3d57bad9dbd3ce5b99cdce5715641696 293 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 29 290 2.6E-104 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1424 3d57bad9dbd3ce5b99cdce5715641696 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 238 249 6.4E-39 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1424 3d57bad9dbd3ce5b99cdce5715641696 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 172 190 6.4E-39 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1424 3d57bad9dbd3ce5b99cdce5715641696 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 138 152 6.4E-39 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1424 3d57bad9dbd3ce5b99cdce5715641696 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 260 269 6.4E-39 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1424 3d57bad9dbd3ce5b99cdce5715641696 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 209 226 6.4E-39 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1424 3d57bad9dbd3ce5b99cdce5715641696 293 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 10 290 34.483 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1424 3d57bad9dbd3ce5b99cdce5715641696 293 SUPERFAMILY SSF52096 37 288 3.73E-72 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MCR_1086 21d326b6a45994e95f2458046a001810 221 Gene3D G3DSA:3.40.50.1360 11 208 2.5E-71 T 14-10-2018 MCR_1086 21d326b6a45994e95f2458046a001810 221 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 212 1.6E-54 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MCR_1086 21d326b6a45994e95f2458046a001810 221 SUPERFAMILY SSF100950 9 148 1.34E-42 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MCR_1086 21d326b6a45994e95f2458046a001810 221 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 7 219 30.535 T 14-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MCR_1086 21d326b6a45994e95f2458046a001810 221 Gene3D G3DSA:3.30.70.260 127 198 2.5E-71 T 14-10-2018 MCR_1086 21d326b6a45994e95f2458046a001810 221 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 10 209 5.0E-61 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MCR_1086 21d326b6a45994e95f2458046a001810 221 SUPERFAMILY SSF75445 129 200 4.32E-20 T 14-10-2018 MCR_1764 f301686cecb8b0eccec977ce7ee45e89 282 Pfam PF09557 Domain of unknown function (DUF2382) 143 252 1.0E-27 T 14-10-2018 IPR019060 Domain of unknown function DUF2382 MCR_1764 f301686cecb8b0eccec977ce7ee45e89 282 SUPERFAMILY SSF50346 21 127 1.96E-24 T 14-10-2018 IPR011033 PRC-barrel-like superfamily MCR_1764 f301686cecb8b0eccec977ce7ee45e89 282 Gene3D G3DSA:3.90.50.10 2 131 4.9E-12 T 14-10-2018 IPR014747 Bacterial photosynthetic reaction centre, H-chain, C-terminal GO:0019684|GO:0030077|GO:0045156 MCR_1764 f301686cecb8b0eccec977ce7ee45e89 282 TIGRFAM TIGR02271 TIGR02271: conserved domain 143 257 8.4E-19 T 14-10-2018 IPR019060 Domain of unknown function DUF2382 MCR_1764 f301686cecb8b0eccec977ce7ee45e89 282 Pfam PF05239 PRC-barrel domain 23 89 3.1E-13 T 14-10-2018 IPR027275 PRC-barrel domain MCR_0268 412584fc316f29303cf68331923ac947 235 SUPERFAMILY SSF53067 116 233 6.47E-26 T 14-10-2018 MCR_0268 412584fc316f29303cf68331923ac947 235 Gene3D G3DSA:3.30.420.40 3 231 1.5E-45 T 14-10-2018 MCR_0268 412584fc316f29303cf68331923ac947 235 Gene3D G3DSA:3.30.420.490 116 226 1.5E-45 T 14-10-2018 MCR_0268 412584fc316f29303cf68331923ac947 235 SUPERFAMILY SSF53067 1 112 3.11E-18 T 14-10-2018 MCR_0268 412584fc316f29303cf68331923ac947 235 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 234 15.797 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MCR_0268 412584fc316f29303cf68331923ac947 235 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 233 6.6E-27 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MCR_0268 412584fc316f29303cf68331923ac947 235 Pfam PF03309 Type III pantothenate kinase 3 193 1.1E-36 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MCR_0692 eed24a0aac4bc2c347466b9d80d6fbd1 503 Gene3D G3DSA:1.25.40.10 124 247 6.5E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0692 eed24a0aac4bc2c347466b9d80d6fbd1 503 Pfam PF04575 Protein of unknown function (DUF560) 222 503 7.2E-98 T 14-10-2018 IPR007655 Protein of unknown function DUF560 MCR_0692 eed24a0aac4bc2c347466b9d80d6fbd1 503 SUPERFAMILY SSF48452 115 200 7.38E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0264 dd7f9fc8764a78301a937e24572c5fc8 724 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 263 348 3.5E-8 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MCR_0264 dd7f9fc8764a78301a937e24572c5fc8 724 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 573 722 1.2E-29 T 14-10-2018 IPR020992 Tail specific protease, C-terminal MCR_0264 dd7f9fc8764a78301a937e24572c5fc8 724 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 232 589 1.8E-75 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 MCR_0264 dd7f9fc8764a78301a937e24572c5fc8 724 Gene3D G3DSA:2.30.42.10 254 358 4.8E-10 T 14-10-2018 MCR_0264 dd7f9fc8764a78301a937e24572c5fc8 724 SMART SM00228 272 352 2.1E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MCR_0264 dd7f9fc8764a78301a937e24572c5fc8 724 Pfam PF03572 Peptidase family S41 390 567 5.6E-44 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MCR_0264 dd7f9fc8764a78301a937e24572c5fc8 724 Gene3D G3DSA:3.90.226.10 359 587 3.6E-53 T 14-10-2018 MCR_0264 dd7f9fc8764a78301a937e24572c5fc8 724 SMART SM00245 356 569 2.1E-47 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MCR_0264 dd7f9fc8764a78301a937e24572c5fc8 724 SUPERFAMILY SSF52096 222 573 1.59E-55 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MCR_0264 dd7f9fc8764a78301a937e24572c5fc8 724 SUPERFAMILY SSF50156 269 368 3.93E-12 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 MCR_1876 321a5143d62a9978fa560afa69c54122 318 Gene3D G3DSA:3.40.50.150 5 305 2.8E-95 T 14-10-2018 MCR_1876 321a5143d62a9978fa560afa69c54122 318 SUPERFAMILY SSF53335 1 316 7.71E-82 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1876 321a5143d62a9978fa560afa69c54122 318 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 67 79 - T 14-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 MCR_1876 321a5143d62a9978fa560afa69c54122 318 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 6 311 4.9E-90 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MCR_1876 321a5143d62a9978fa560afa69c54122 318 Pfam PF00145 C-5 cytosine-specific DNA methylase 4 313 1.6E-84 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MCR_1876 321a5143d62a9978fa560afa69c54122 318 Gene3D G3DSA:3.90.120.10 184 275 2.8E-95 T 14-10-2018 MCR_1876 321a5143d62a9978fa560afa69c54122 318 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 154 167 1.9E-15 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MCR_1876 321a5143d62a9978fa560afa69c54122 318 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 5 21 1.9E-15 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MCR_1876 321a5143d62a9978fa560afa69c54122 318 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 106 120 1.9E-15 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MCR_1541 c95e4d3f6c6c3e5f7f7d10e4ea321ee1 196 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 158 41.282 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MCR_1541 c95e4d3f6c6c3e5f7f7d10e4ea321ee1 196 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 4.1E-34 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MCR_1541 c95e4d3f6c6c3e5f7f7d10e4ea321ee1 196 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 112 131 4.1E-34 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MCR_1541 c95e4d3f6c6c3e5f7f7d10e4ea321ee1 196 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 88 104 4.1E-34 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MCR_1541 c95e4d3f6c6c3e5f7f7d10e4ea321ee1 196 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 66 82 4.1E-34 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MCR_1541 c95e4d3f6c6c3e5f7f7d10e4ea321ee1 196 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 143 155 4.1E-34 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MCR_1541 c95e4d3f6c6c3e5f7f7d10e4ea321ee1 196 SUPERFAMILY SSF53098 3 160 2.2E-47 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MCR_1541 c95e4d3f6c6c3e5f7f7d10e4ea321ee1 196 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 118 152 - T 14-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 MCR_1541 c95e4d3f6c6c3e5f7f7d10e4ea321ee1 196 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 155 1.1E-51 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MCR_1541 c95e4d3f6c6c3e5f7f7d10e4ea321ee1 196 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 163 6.9E-56 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MCR_1541 c95e4d3f6c6c3e5f7f7d10e4ea321ee1 196 Gene3D G3DSA:3.30.420.10 2 163 6.9E-46 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 252 261 6.8E-25 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 264 287 6.8E-25 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 131 142 6.8E-25 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 6.8E-25 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 150 297 6.5E-49 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 144 1.2E-46 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 Gene3D G3DSA:3.40.50.1370 134 286 2.2E-109 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 3 300 74.877 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 SUPERFAMILY SSF53671 2 301 2.23E-101 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 4 299 1.8E-113 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 278 289 2.3E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 120 134 2.3E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 216 226 2.3E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 47 61 2.3E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 80 93 2.3E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 Gene3D G3DSA:3.40.50.1370 12 295 2.2E-109 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MCR_0861 8fcda49de2b5a112802b9b5df3e84436 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MCR_0215 aca4bd6d6c713b022fd5b164d2931518 528 SUPERFAMILY SSF56317 229 489 9.16E-41 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MCR_0215 aca4bd6d6c713b022fd5b164d2931518 528 Gene3D G3DSA:3.60.110.10 254 477 2.0E-17 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MCR_0215 aca4bd6d6c713b022fd5b164d2931518 528 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 19 496 22.154 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MCR_0215 aca4bd6d6c713b022fd5b164d2931518 528 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 73 459 7.0E-92 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MCR_0215 aca4bd6d6c713b022fd5b164d2931518 528 Pfam PF00795 Carbon-nitrogen hydrolase 232 483 1.9E-32 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 Pfam PF13481 AAA domain 91 232 5.8E-15 T 14-10-2018 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 Hamap MF_01498 DNA repair protein RadA [radA]. 21 467 42.305 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 SUPERFAMILY SSF54211 265 468 9.86E-40 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 PRINTS PR01874 DNA repair protein radA signature 89 117 5.5E-81 T 14-10-2018 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 PRINTS PR01874 DNA repair protein radA signature 10 34 5.5E-81 T 14-10-2018 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 PRINTS PR01874 DNA repair protein radA signature 184 208 5.5E-81 T 14-10-2018 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 PRINTS PR01874 DNA repair protein radA signature 223 251 5.5E-81 T 14-10-2018 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 PRINTS PR01874 DNA repair protein radA signature 331 354 5.5E-81 T 14-10-2018 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 PRINTS PR01874 DNA repair protein radA signature 258 284 5.5E-81 T 14-10-2018 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 Pfam PF13541 Subunit ChlI of Mg-chelatase 364 439 1.7E-6 T 14-10-2018 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 Gene3D G3DSA:3.30.230.10 326 470 2.5E-18 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 SMART SM00382 97 254 7.4E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 463 1.6E-185 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 Gene3D G3DSA:3.40.50.300 75 294 2.4E-39 T 14-10-2018 MCR_1000 71d226bed2467687b42e09ec0c240d5c 472 SUPERFAMILY SSF52540 78 297 8.3E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0694 705c0eb85c4dca0d14dd450cd98ca55a 708 Gene3D G3DSA:2.40.128.240 460 556 6.0E-12 T 14-10-2018 IPR038197 TbpB, C-lobe handle domain superfamily MCR_0694 705c0eb85c4dca0d14dd450cd98ca55a 708 SUPERFAMILY SSF56925 228 437 4.0E-34 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MCR_0694 705c0eb85c4dca0d14dd450cd98ca55a 708 SUPERFAMILY SSF56925 533 702 2.2E-26 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MCR_0694 705c0eb85c4dca0d14dd450cd98ca55a 708 Gene3D G3DSA:2.40.160.90 561 705 2.5E-35 T 14-10-2018 MCR_0694 705c0eb85c4dca0d14dd450cd98ca55a 708 Pfam PF17484 N-Lobe handle Tf-binding protein B 79 266 7.5E-12 T 14-10-2018 IPR035313 Transferrin-binding protein B, N-lobe handle MCR_0694 705c0eb85c4dca0d14dd450cd98ca55a 708 Pfam PF01298 C-lobe and N-lobe beta barrels of Tf-binding protein B 269 437 2.0E-40 T 14-10-2018 IPR001677 Transferrin-binding protein, C-lobe/N-lobe beta barrel domain MCR_0694 705c0eb85c4dca0d14dd450cd98ca55a 708 Pfam PF01298 C-lobe and N-lobe beta barrels of Tf-binding protein B 565 702 1.3E-30 T 14-10-2018 IPR001677 Transferrin-binding protein, C-lobe/N-lobe beta barrel domain MCR_0694 705c0eb85c4dca0d14dd450cd98ca55a 708 Gene3D G3DSA:2.40.128.250 94 265 5.8E-12 T 14-10-2018 IPR038669 TbpB, N-lobe handle domain superfamily MCR_0694 705c0eb85c4dca0d14dd450cd98ca55a 708 Gene3D G3DSA:2.40.160.90 266 459 6.5E-54 T 14-10-2018 MCR_0694 705c0eb85c4dca0d14dd450cd98ca55a 708 Pfam PF17483 C-lobe handle domain of Tf-binding protein B 457 557 3.0E-22 T 14-10-2018 IPR035316 Transferrin-binding protein B, C-lobe handle domain MCR_0123 33fd744a7da36470ede1b10c0282eb25 247 SMART SM00345 15 74 3.9E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MCR_0123 33fd744a7da36470ede1b10c0282eb25 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.3E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MCR_0123 33fd744a7da36470ede1b10c0282eb25 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.6E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MCR_0123 33fd744a7da36470ede1b10c0282eb25 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.6E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MCR_0123 33fd744a7da36470ede1b10c0282eb25 247 SUPERFAMILY SSF46785 6 78 1.16E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0123 33fd744a7da36470ede1b10c0282eb25 247 Gene3D G3DSA:3.40.1410.10 72 236 2.6E-20 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MCR_0123 33fd744a7da36470ede1b10c0282eb25 247 SMART SM00866 95 242 3.4E-14 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MCR_0123 33fd744a7da36470ede1b10c0282eb25 247 Pfam PF07702 UTRA domain 136 241 2.2E-19 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MCR_0123 33fd744a7da36470ede1b10c0282eb25 247 Gene3D G3DSA:1.10.10.10 7 71 3.2E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0123 33fd744a7da36470ede1b10c0282eb25 247 SUPERFAMILY SSF64288 64 246 4.55E-28 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MCR_1376 4d1c7382782a43478ec042813544f78f 867 Gene3D G3DSA:1.10.1740.60 208 292 5.6E-36 T 14-10-2018 MCR_1376 4d1c7382782a43478ec042813544f78f 867 SUPERFAMILY SSF63737 15 205 1.44E-37 T 14-10-2018 MCR_1376 4d1c7382782a43478ec042813544f78f 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 307 322 1.7E-9 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MCR_1376 4d1c7382782a43478ec042813544f78f 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 326 338 1.7E-9 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MCR_1376 4d1c7382782a43478ec042813544f78f 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 271 281 1.7E-9 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MCR_1376 4d1c7382782a43478ec042813544f78f 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 189 204 1.7E-9 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MCR_1376 4d1c7382782a43478ec042813544f78f 867 Gene3D G3DSA:2.60.40.1730 25 207 2.5E-60 T 14-10-2018 MCR_1376 4d1c7382782a43478ec042813544f78f 867 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 22 862 1.1E-276 T 14-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 MCR_1376 4d1c7382782a43478ec042813544f78f 867 Gene3D G3DSA:2.60.40.1840 456 552 6.7E-13 T 14-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily MCR_1376 4d1c7382782a43478ec042813544f78f 867 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 555 863 5.6E-72 T 14-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal MCR_1376 4d1c7382782a43478ec042813544f78f 867 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 456 552 9.2E-18 T 14-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold MCR_1376 4d1c7382782a43478ec042813544f78f 867 Gene3D G3DSA:1.25.50.10 553 863 1.0E-63 T 14-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily MCR_1376 4d1c7382782a43478ec042813544f78f 867 SUPERFAMILY SSF55486 218 460 4.03E-67 T 14-10-2018 MCR_1376 4d1c7382782a43478ec042813544f78f 867 Pfam PF01433 Peptidase family M1 domain 221 445 1.5E-53 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MCR_1376 4d1c7382782a43478ec042813544f78f 867 Gene3D G3DSA:1.10.390.10 293 455 2.1E-56 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily MCR_0766 871e016ef3ea8358b6988c8baf60803b 448 Pfam PF07690 Major Facilitator Superfamily 41 408 5.5E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MCR_0766 871e016ef3ea8358b6988c8baf60803b 448 Gene3D G3DSA:1.20.1250.20 234 445 9.4E-68 T 14-10-2018 MCR_0766 871e016ef3ea8358b6988c8baf60803b 448 Gene3D G3DSA:1.20.1250.20 2 233 2.7E-80 T 14-10-2018 MCR_0766 871e016ef3ea8358b6988c8baf60803b 448 TIGRFAM TIGR00886 2A0108: nitrite transporter 32 404 1.7E-103 T 14-10-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 MCR_0766 871e016ef3ea8358b6988c8baf60803b 448 SUPERFAMILY SSF103473 32 442 4.97E-40 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_1626 ead5961b7a913dba7d23db35e6b51fb8 255 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 255 74.689 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MCR_1626 ead5961b7a913dba7d23db35e6b51fb8 255 Gene3D G3DSA:2.30.210.20 14 71 3.4E-18 T 14-10-2018 MCR_1626 ead5961b7a913dba7d23db35e6b51fb8 255 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 47 235 2.5E-55 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MCR_1626 ead5961b7a913dba7d23db35e6b51fb8 255 SUPERFAMILY SSF55729 29 235 2.01E-77 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MCR_1626 ead5961b7a913dba7d23db35e6b51fb8 255 Gene3D G3DSA:3.40.630.70 72 243 2.5E-58 T 14-10-2018 MCR_1626 ead5961b7a913dba7d23db35e6b51fb8 255 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 46 218 5.3E-66 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MCR_0090 fed77b1629a26931598bd72791dc5cef 374 Pfam PF07007 Lysozyme inhibitor LprI 297 370 2.7E-5 T 14-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal MCR_0090 fed77b1629a26931598bd72791dc5cef 374 SMART SM00271 4 57 3.6E-11 T 14-10-2018 IPR001623 DnaJ domain MCR_0090 fed77b1629a26931598bd72791dc5cef 374 Gene3D G3DSA:1.10.287.110 1 79 8.3E-16 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MCR_0090 fed77b1629a26931598bd72791dc5cef 374 SUPERFAMILY SSF46565 3 66 8.9E-15 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MCR_0090 fed77b1629a26931598bd72791dc5cef 374 PRINTS PR00625 DnaJ domain signature 7 25 6.4E-6 T 14-10-2018 IPR001623 DnaJ domain MCR_0090 fed77b1629a26931598bd72791dc5cef 374 PRINTS PR00625 DnaJ domain signature 37 57 6.4E-6 T 14-10-2018 IPR001623 DnaJ domain MCR_0090 fed77b1629a26931598bd72791dc5cef 374 Pfam PF00226 DnaJ domain 5 62 2.2E-12 T 14-10-2018 IPR001623 DnaJ domain MCR_1026 6aaf0d0b4ca0141ad4cda7f082ecf1f3 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1026 6aaf0d0b4ca0141ad4cda7f082ecf1f3 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1026 6aaf0d0b4ca0141ad4cda7f082ecf1f3 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1026 6aaf0d0b4ca0141ad4cda7f082ecf1f3 290 Gene3D G3DSA:3.40.190.290 92 289 6.8E-38 T 14-10-2018 MCR_1026 6aaf0d0b4ca0141ad4cda7f082ecf1f3 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 1.7E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1026 6aaf0d0b4ca0141ad4cda7f082ecf1f3 290 SUPERFAMILY SSF46785 1 111 5.99E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_1026 6aaf0d0b4ca0141ad4cda7f082ecf1f3 290 Pfam PF03466 LysR substrate binding domain 89 286 2.1E-37 T 14-10-2018 IPR005119 LysR, substrate-binding MCR_1026 6aaf0d0b4ca0141ad4cda7f082ecf1f3 290 Gene3D G3DSA:1.10.10.10 1 91 8.4E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_1026 6aaf0d0b4ca0141ad4cda7f082ecf1f3 290 SUPERFAMILY SSF53850 90 286 7.47E-36 T 14-10-2018 MCR_1345 647afb970b2ff15b5ad40b0f15d33b79 477 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 42 309 3.0E-55 T 14-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 MCR_1345 647afb970b2ff15b5ad40b0f15d33b79 477 SUPERFAMILY SSF56300 42 404 1.73E-44 T 14-10-2018 MCR_1345 647afb970b2ff15b5ad40b0f15d33b79 477 Gene3D G3DSA:3.30.160.720 354 414 6.3E-7 T 14-10-2018 MCR_1345 647afb970b2ff15b5ad40b0f15d33b79 477 Gene3D G3DSA:3.60.21.10 35 329 1.6E-77 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like MCR_1345 647afb970b2ff15b5ad40b0f15d33b79 477 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 353 449 1.5E-11 T 14-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain MCR_1345 647afb970b2ff15b5ad40b0f15d33b79 477 Pfam PF00149 Calcineurin-like phosphoesterase 42 281 1.8E-14 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MCR_0800 bcbfa40f92f1cedc60f59d3512fc1836 212 Pfam PF04279 Intracellular septation protein A 1 200 1.2E-42 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 MCR_0800 bcbfa40f92f1cedc60f59d3512fc1836 212 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 201 15.09 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 MCR_1373 0a75c52c5208846713f6c208829f1ddb 407 SUPERFAMILY SSF52266 41 370 1.95E-25 T 14-10-2018 MCR_1373 0a75c52c5208846713f6c208829f1ddb 407 Gene3D G3DSA:3.40.50.1110 39 364 1.2E-95 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MCR_1373 0a75c52c5208846713f6c208829f1ddb 407 Pfam PF00657 GDSL-like Lipase/Acylhydrolase 43 363 1.9E-14 T 14-10-2018 IPR001087 GDSL lipase/esterase GO:0016788 MCR_1373 0a75c52c5208846713f6c208829f1ddb 407 Gene3D G3DSA:2.60.120.1360 72 206 1.2E-95 T 14-10-2018 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 SMART SM01382 124 251 5.8E-86 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 272 1.0E-125 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 45.797 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 SUPERFAMILY SSF50249 3 124 1.13E-48 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 SMART SM01383 42 118 1.3E-47 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 Gene3D G3DSA:4.10.950.10 196 273 1.2E-33 T 14-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 14-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 249 1.7E-54 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 Gene3D G3DSA:2.30.30.30 115 195 3.1E-32 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 PIRSF PIRSF002158 12 274 1.3E-103 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 Gene3D G3DSA:2.40.50.140 1 114 3.3E-49 T 14-10-2018 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 6.3E-35 T 14-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1582 e4a7a3e4306ee8935af038d131b0a9d8 275 SUPERFAMILY SSF50104 126 269 9.03E-59 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily MCR_0577 2e9da72240eeaff49022974f4ff36b0e 348 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 348 46.448 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_0577 2e9da72240eeaff49022974f4ff36b0e 348 SUPERFAMILY SSF56042 171 346 5.08E-62 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MCR_0577 2e9da72240eeaff49022974f4ff36b0e 348 Pfam PF00586 AIR synthase related protein, N-terminal domain 64 164 2.9E-15 T 14-10-2018 IPR016188 PurM-like, N-terminal domain MCR_0577 2e9da72240eeaff49022974f4ff36b0e 348 SUPERFAMILY SSF55326 7 169 2.09E-52 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MCR_0577 2e9da72240eeaff49022974f4ff36b0e 348 Pfam PF02769 AIR synthase related protein, C-terminal domain 176 346 6.3E-39 T 14-10-2018 IPR010918 PurM-like, C-terminal domain MCR_0577 2e9da72240eeaff49022974f4ff36b0e 348 Gene3D G3DSA:3.30.1330.10 7 170 3.7E-67 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MCR_0577 2e9da72240eeaff49022974f4ff36b0e 348 Gene3D G3DSA:3.90.650.10 171 347 7.4E-68 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MCR_0577 2e9da72240eeaff49022974f4ff36b0e 348 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 7 339 7.2E-144 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MCR_1267 4d1435f10a26f475ae322e72ae068144 148 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 11 28 6.7E-33 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MCR_1267 4d1435f10a26f475ae322e72ae068144 148 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 70 90 6.7E-33 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MCR_1267 4d1435f10a26f475ae322e72ae068144 148 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 94 116 6.7E-33 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MCR_1267 4d1435f10a26f475ae322e72ae068144 148 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 120 138 6.7E-33 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MCR_1267 4d1435f10a26f475ae322e72ae068144 148 Pfam PF02556 Preprotein translocase subunit SecB 4 138 9.8E-51 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MCR_1267 4d1435f10a26f475ae322e72ae068144 148 Hamap MF_00821 Protein-export protein SecB [secB]. 1 142 30.961 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MCR_1267 4d1435f10a26f475ae322e72ae068144 148 Gene3D G3DSA:3.10.420.10 1 148 7.2E-52 T 14-10-2018 IPR035958 SecB-like superfamily MCR_1267 4d1435f10a26f475ae322e72ae068144 148 SUPERFAMILY SSF54611 3 137 2.62E-46 T 14-10-2018 IPR035958 SecB-like superfamily MCR_1267 4d1435f10a26f475ae322e72ae068144 148 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 3 138 5.7E-52 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MCR_0886 57d92a7ce38be74b3b22956b950f4c17 54 Pfam PF00301 Rubredoxin 3 49 1.5E-23 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 MCR_0886 57d92a7ce38be74b3b22956b950f4c17 54 PIRSF PIRSF000071 1 54 1.8E-26 T 14-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 MCR_0886 57d92a7ce38be74b3b22956b950f4c17 54 SUPERFAMILY SSF57802 1 53 2.52E-23 T 14-10-2018 MCR_0886 57d92a7ce38be74b3b22956b950f4c17 54 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 14-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 MCR_0886 57d92a7ce38be74b3b22956b950f4c17 54 Gene3D G3DSA:2.20.28.10 1 54 3.6E-29 T 14-10-2018 MCR_0886 57d92a7ce38be74b3b22956b950f4c17 54 PRINTS PR00163 Rubredoxin signature 33 49 1.6E-10 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 MCR_0886 57d92a7ce38be74b3b22956b950f4c17 54 PRINTS PR00163 Rubredoxin signature 3 19 1.6E-10 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 MCR_1090 2b3cb20c0c51d8c3f38f554629c1796c 469 SUPERFAMILY SSF54368 3 99 2.88E-32 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MCR_1090 2b3cb20c0c51d8c3f38f554629c1796c 469 Gene3D G3DSA:3.30.590.10 104 457 2.0E-134 T 14-10-2018 MCR_1090 2b3cb20c0c51d8c3f38f554629c1796c 469 Gene3D G3DSA:3.10.20.70 2 103 5.2E-34 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MCR_1090 2b3cb20c0c51d8c3f38f554629c1796c 469 Pfam PF00120 Glutamine synthetase, catalytic domain 102 466 1.8E-128 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MCR_1090 2b3cb20c0c51d8c3f38f554629c1796c 469 SUPERFAMILY SSF55931 102 468 2.26E-124 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MCR_1090 2b3cb20c0c51d8c3f38f554629c1796c 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 14-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MCR_1090 2b3cb20c0c51d8c3f38f554629c1796c 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 14-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MCR_1090 2b3cb20c0c51d8c3f38f554629c1796c 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 467 8.9E-189 T 14-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MCR_1090 2b3cb20c0c51d8c3f38f554629c1796c 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 94 8.0E-29 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MCR_1090 2b3cb20c0c51d8c3f38f554629c1796c 469 SMART SM01230 101 379 5.7E-127 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MCR_1090 2b3cb20c0c51d8c3f38f554629c1796c 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MCR_0762 e50856eaa608b3d9e0848f9da8055dba 361 Pfam PF13353 4Fe-4S single cluster domain 59 158 1.8E-10 T 14-10-2018 MCR_0762 e50856eaa608b3d9e0848f9da8055dba 361 Gene3D G3DSA:3.20.20.70 36 361 2.2E-70 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0762 e50856eaa608b3d9e0848f9da8055dba 361 SUPERFAMILY SSF102114 40 311 8.24E-59 T 14-10-2018 MCR_0762 e50856eaa608b3d9e0848f9da8055dba 361 Pfam PF04055 Radical SAM superfamily 54 173 8.8E-17 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MCR_0762 e50856eaa608b3d9e0848f9da8055dba 361 Pfam PF06463 Molybdenum Cofactor Synthesis C 221 344 9.8E-32 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0762 e50856eaa608b3d9e0848f9da8055dba 361 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 55 66 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0762 e50856eaa608b3d9e0848f9da8055dba 361 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 40 361 3.0E-88 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0410 082e4822cfb7c8d62de767a13d9daf54 390 Pfam PF01594 AI-2E family transporter 16 346 4.7E-42 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 470 3.0E-143 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 Gene3D G3DSA:1.10.10.350 372 495 1.7E-28 T 14-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 472 30.685 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 Gene3D G3DSA:3.40.50.620 1 329 4.0E-147 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 321 1.6E-108 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 SUPERFAMILY SSF52374 4 309 1.49E-110 T 14-10-2018 MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 4.6E-23 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 4.6E-23 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 4.6E-23 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 4.6E-23 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 4.6E-23 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_1779 e15cc676906ba01237887f4c85cc5d3e 498 SUPERFAMILY SSF48163 315 472 7.98E-37 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MCR_0224 6dfb0963115229962aaace318cf5071d 410 SUPERFAMILY SSF53901 215 408 3.13E-62 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0224 6dfb0963115229962aaace318cf5071d 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 247 4.2E-38 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MCR_0224 6dfb0963115229962aaace318cf5071d 410 Gene3D G3DSA:3.40.47.10 1 255 5.3E-58 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0224 6dfb0963115229962aaace318cf5071d 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 365 1.2E-33 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MCR_0224 6dfb0963115229962aaace318cf5071d 410 SUPERFAMILY SSF53901 1 254 1.05E-58 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0224 6dfb0963115229962aaace318cf5071d 410 SMART SM00825 Beta-ketoacyl synthase 4 410 1.4E-13 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MCR_0224 6dfb0963115229962aaace318cf5071d 410 Gene3D G3DSA:3.40.47.10 261 410 9.0E-47 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0224 6dfb0963115229962aaace318cf5071d 410 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site MCR_0458 5128e0187c390aaf41d78c6729caaf45 329 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 329 166.719 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MCR_0458 5128e0187c390aaf41d78c6729caaf45 329 SMART SM00382 52 183 9.0E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0458 5128e0187c390aaf41d78c6729caaf45 329 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 323 8.9E-29 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MCR_0458 5128e0187c390aaf41d78c6729caaf45 329 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 10 236 8.6E-115 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MCR_0458 5128e0187c390aaf41d78c6729caaf45 329 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 251 323 1.0E-15 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MCR_0458 5128e0187c390aaf41d78c6729caaf45 329 SUPERFAMILY SSF46785 258 324 2.0E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0458 5128e0187c390aaf41d78c6729caaf45 329 SUPERFAMILY SSF52540 21 252 1.84E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0458 5128e0187c390aaf41d78c6729caaf45 329 Gene3D G3DSA:3.40.50.300 19 182 7.4E-38 T 14-10-2018 MCR_0458 5128e0187c390aaf41d78c6729caaf45 329 Gene3D G3DSA:1.10.10.10 258 327 1.1E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0458 5128e0187c390aaf41d78c6729caaf45 329 Gene3D G3DSA:1.10.8.60 183 257 6.6E-30 T 14-10-2018 MCR_0458 5128e0187c390aaf41d78c6729caaf45 329 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 323 1.9E-139 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MCR_0914 c24f05d690ed4de594659f1f02d59e2e 242 SUPERFAMILY SSF52540 3 236 3.99E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0914 c24f05d690ed4de594659f1f02d59e2e 242 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 5 240 4.6E-116 T 14-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 MCR_0914 c24f05d690ed4de594659f1f02d59e2e 242 Gene3D G3DSA:3.40.50.300 3 242 1.3E-67 T 14-10-2018 MCR_0914 c24f05d690ed4de594659f1f02d59e2e 242 Pfam PF00005 ABC transporter 21 167 7.0E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0914 c24f05d690ed4de594659f1f02d59e2e 242 SMART SM00382 29 240 3.3E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0255 7c60986cda8dee55517bb8102f530477 167 Gene3D G3DSA:3.30.70.1730 1 125 2.3E-38 T 14-10-2018 MCR_0255 7c60986cda8dee55517bb8102f530477 167 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 14-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0255 7c60986cda8dee55517bb8102f530477 167 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 78 144 2.0E-4 T 14-10-2018 MCR_0255 7c60986cda8dee55517bb8102f530477 167 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 162 28.052 T 14-10-2018 IPR022973 Ribosomal protein L10 MCR_0255 7c60986cda8dee55517bb8102f530477 167 SUPERFAMILY SSF160369 4 161 1.44E-50 T 14-10-2018 MCR_0255 7c60986cda8dee55517bb8102f530477 167 Pfam PF00466 Ribosomal protein L10 5 101 1.0E-27 T 14-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 MCR_1771 6586ae1741b73f30e0ade8c6ea769a01 100 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 72 5.9E-26 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MCR_1771 6586ae1741b73f30e0ade8c6ea769a01 100 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 2.4E-39 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MCR_1771 6586ae1741b73f30e0ade8c6ea769a01 100 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 2.4E-39 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MCR_1771 6586ae1741b73f30e0ade8c6ea769a01 100 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 2.4E-39 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MCR_1771 6586ae1741b73f30e0ade8c6ea769a01 100 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 2.4E-39 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MCR_1771 6586ae1741b73f30e0ade8c6ea769a01 100 Pfam PF03840 Preprotein translocase SecG subunit 4 71 6.7E-21 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MCR_1152 47015716d9421be4fe90ef7a593f6b60 410 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 183 408 2.5E-80 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MCR_1152 47015716d9421be4fe90ef7a593f6b60 410 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 11 408 3.4E-164 T 14-10-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MCR_1152 47015716d9421be4fe90ef7a593f6b60 410 SUPERFAMILY SSF51690 129 407 1.18E-86 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MCR_1152 47015716d9421be4fe90ef7a593f6b60 410 SUPERFAMILY SSF54675 8 146 4.24E-39 T 14-10-2018 MCR_1152 47015716d9421be4fe90ef7a593f6b60 410 PIRSF PIRSF000484 3 406 1.6E-81 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MCR_1152 47015716d9421be4fe90ef7a593f6b60 410 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 8 410 46.836 T 14-10-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MCR_1152 47015716d9421be4fe90ef7a593f6b60 410 Gene3D G3DSA:3.20.140.10 4 410 3.3E-148 T 14-10-2018 MCR_0612 426edd3169975e4991d002f7400633f3 90 Gene3D G3DSA:4.10.520.10 1 90 3.0E-38 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MCR_0612 426edd3169975e4991d002f7400633f3 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.6E-36 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0612 426edd3169975e4991d002f7400633f3 90 SMART SM00411 1 90 3.7E-45 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0612 426edd3169975e4991d002f7400633f3 90 SUPERFAMILY SSF47729 1 90 4.27E-34 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MCR_0612 426edd3169975e4991d002f7400633f3 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 7.1E-19 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0612 426edd3169975e4991d002f7400633f3 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 7.1E-19 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0612 426edd3169975e4991d002f7400633f3 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 7.1E-19 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MCR_0612 426edd3169975e4991d002f7400633f3 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MCR_1462 0f57eefe02361534e34f5671e67830bb 202 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 3 200 3.0E-102 T 14-10-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MCR_1462 0f57eefe02361534e34f5671e67830bb 202 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 200 2.8E-58 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MCR_1462 0f57eefe02361534e34f5671e67830bb 202 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 202 29.398 T 14-10-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MCR_1462 0f57eefe02361534e34f5671e67830bb 202 PIRSF PIRSF006102 1 202 5.6E-58 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 Pfam PF00970 Oxidoreductase FAD-binding domain 16 98 5.7E-6 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 145 4.6E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 4.6E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 4.6E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 51 58 4.6E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 SUPERFAMILY SSF52343 102 255 3.27E-44 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 Gene3D G3DSA:3.40.50.80 100 254 2.4E-43 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 Pfam PF00175 Oxidoreductase NAD-binding domain 112 228 1.2E-11 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 SUPERFAMILY SSF63380 3 99 3.05E-23 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 Gene3D G3DSA:2.40.30.10 1 96 3.2E-26 T 14-10-2018 MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 PRINTS PR00410 Phenol hydroxylase reductase family signature 51 58 1.3E-5 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 PRINTS PR00410 Phenol hydroxylase reductase family signature 136 145 1.3E-5 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MCR_0472 0f4ed1a23f68099411bde2977eb73725 257 PRINTS PR00410 Phenol hydroxylase reductase family signature 111 130 1.3E-5 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MCR_1414 38fcd1b1fbebc8be14010d65877d19a5 202 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 6 193 2.3E-72 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MCR_1414 38fcd1b1fbebc8be14010d65877d19a5 202 SUPERFAMILY SSF142695 3 172 1.96E-57 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MCR_1414 38fcd1b1fbebc8be14010d65877d19a5 202 Gene3D G3DSA:3.40.50.10990 2 173 8.2E-71 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MCR_1414 38fcd1b1fbebc8be14010d65877d19a5 202 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 2 195 40.042 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MCR_1414 38fcd1b1fbebc8be14010d65877d19a5 202 Pfam PF00925 GTP cyclohydrolase II 7 169 5.1E-63 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MCR_0354 e9602aa41e2a6c9c18a3c3f6b096bf97 313 Gene3D G3DSA:3.40.1010.20 6 283 1.5E-110 T 14-10-2018 MCR_0354 e9602aa41e2a6c9c18a3c3f6b096bf97 313 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 287 37.474 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MCR_0354 e9602aa41e2a6c9c18a3c3f6b096bf97 313 Pfam PF02401 LytB protein 3 283 1.3E-90 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MCR_0354 e9602aa41e2a6c9c18a3c3f6b096bf97 313 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 284 1.1E-96 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MCR_0354 e9602aa41e2a6c9c18a3c3f6b096bf97 313 Gene3D G3DSA:3.40.50.11270 12 96 1.5E-110 T 14-10-2018 MCR_0354 e9602aa41e2a6c9c18a3c3f6b096bf97 313 Gene3D G3DSA:3.40.1010.20 97 197 1.5E-110 T 14-10-2018 MCR_1038 55f3707e081a842e61916b9592d6c51e 158 PRINTS PR00601 Bacterioferritin signature 65 85 2.8E-53 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1038 55f3707e081a842e61916b9592d6c51e 158 PRINTS PR00601 Bacterioferritin signature 107 127 2.8E-53 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1038 55f3707e081a842e61916b9592d6c51e 158 PRINTS PR00601 Bacterioferritin signature 86 106 2.8E-53 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1038 55f3707e081a842e61916b9592d6c51e 158 PRINTS PR00601 Bacterioferritin signature 44 64 2.8E-53 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1038 55f3707e081a842e61916b9592d6c51e 158 PRINTS PR00601 Bacterioferritin signature 23 43 2.8E-53 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1038 55f3707e081a842e61916b9592d6c51e 158 PRINTS PR00601 Bacterioferritin signature 128 149 2.8E-53 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1038 55f3707e081a842e61916b9592d6c51e 158 PRINTS PR00601 Bacterioferritin signature 3 22 2.8E-53 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1038 55f3707e081a842e61916b9592d6c51e 158 Gene3D G3DSA:1.20.1260.10 1 158 4.1E-55 T 14-10-2018 IPR012347 Ferritin-like MCR_1038 55f3707e081a842e61916b9592d6c51e 158 Pfam PF00210 Ferritin-like domain 9 143 1.5E-28 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MCR_1038 55f3707e081a842e61916b9592d6c51e 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 154 6.0E-62 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1038 55f3707e081a842e61916b9592d6c51e 158 SUPERFAMILY SSF47240 1 153 5.19E-43 T 14-10-2018 IPR009078 Ferritin-like superfamily MCR_1038 55f3707e081a842e61916b9592d6c51e 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1038 55f3707e081a842e61916b9592d6c51e 158 PIRSF PIRSF002560 1 157 2.5E-59 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 6 871 0.0 T 14-10-2018 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 SUPERFAMILY SSF101904 541 881 6.8E-96 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Gene3D G3DSA:2.120.10.90 538 870 3.7E-111 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Gene3D G3DSA:3.90.199.10 30 529 2.7E-211 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 SMART SM00434 8 507 1.5E-255 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 655 697 1.5E-8 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 825 870 2.0E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 597 646 2.3E-8 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 548 593 1.5E-8 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 774 820 1.1E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 701 746 5.0E-10 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 29 506 3.5E-149 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Gene3D G3DSA:3.30.1360.40 233 334 2.7E-211 T 14-10-2018 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Gene3D G3DSA:1.10.268.10 371 501 2.7E-211 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 SUPERFAMILY SSF56719 27 530 1.28E-170 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MCR_1057 3e0c1d00a4e124ce05edc9f644adcb63 888 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 2 872 23.249 T 14-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 Gene3D G3DSA:2.40.50.140 8 121 7.5E-32 T 14-10-2018 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 Gene3D G3DSA:3.30.930.10 134 604 7.4E-194 T 14-10-2018 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 Pfam PF02938 GAD domain 325 430 7.3E-27 T 14-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 220 1.5E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 PRINTS PR01042 Aspartyl-tRNA synthetase signature 225 238 1.5E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 PRINTS PR01042 Aspartyl-tRNA synthetase signature 496 512 1.5E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 PRINTS PR01042 Aspartyl-tRNA synthetase signature 540 554 1.5E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 Gene3D G3DSA:3.30.1360.30 289 444 7.4E-194 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 SUPERFAMILY SSF55261 307 443 5.23E-43 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 Pfam PF00152 tRNA synthetases class II (D, K and N) 135 580 1.8E-106 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 Pfam PF01336 OB-fold nucleic acid binding domain 34 117 2.2E-16 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 SUPERFAMILY SSF55681 124 606 5.35E-103 T 14-10-2018 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 15 604 5.4E-235 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 SUPERFAMILY SSF50249 16 120 8.76E-31 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1187 79f7e28775bed24e219a61e7731ec5e4 612 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 16 606 32.952 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MCR_1598 299b111c4d33140e80d29d29d2c8c5c5 260 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 154 248 3.9E-23 T 14-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 MCR_1598 299b111c4d33140e80d29d29d2c8c5c5 260 Gene3D G3DSA:2.160.20.70 134 255 5.2E-23 T 14-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 MCR_1598 299b111c4d33140e80d29d29d2c8c5c5 260 Gene3D G3DSA:3.30.750.120 1 108 9.6E-6 T 14-10-2018 IPR038061 MinC, Proteobacteria, N-terminal domain superfamily MCR_1598 299b111c4d33140e80d29d29d2c8c5c5 260 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 4 258 17.271 T 14-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MCR_1598 299b111c4d33140e80d29d29d2c8c5c5 260 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 5 248 3.4E-31 T 14-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MCR_1598 299b111c4d33140e80d29d29d2c8c5c5 260 SUPERFAMILY SSF63848 153 248 1.31E-22 T 14-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 MCR_1605 75bdae737739c94b734a2b830718a2f9 469 PIRSF PIRSF000167 19 468 8.0E-155 T 14-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 MCR_1605 75bdae737739c94b734a2b830718a2f9 469 Gene3D G3DSA:1.10.10.920 377 469 5.7E-30 T 14-10-2018 MCR_1605 75bdae737739c94b734a2b830718a2f9 469 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 19 469 8.1E-167 T 14-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 MCR_1605 75bdae737739c94b734a2b830718a2f9 469 SMART SM00729 64 282 4.1E-41 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MCR_1605 75bdae737739c94b734a2b830718a2f9 469 Pfam PF06969 HemN C-terminal domain 378 443 1.1E-11 T 14-10-2018 IPR010723 HemN, C-terminal MCR_1605 75bdae737739c94b734a2b830718a2f9 469 Pfam PF04055 Radical SAM superfamily 69 241 2.6E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MCR_1605 75bdae737739c94b734a2b830718a2f9 469 SUPERFAMILY SSF102114 20 457 3.79E-122 T 14-10-2018 MCR_1605 75bdae737739c94b734a2b830718a2f9 469 Gene3D G3DSA:3.80.30.20 14 375 6.3E-114 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 ProSitePatterns PS00211 ABC transporters family signature. 846 860 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 Pfam PF00005 ABC transporter 822 876 1.2E-5 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 Gene3D G3DSA:1.20.1580.10 708 846 4.8E-143 T 14-10-2018 MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 Gene3D G3DSA:3.30.190.20 132 248 2.3E-240 T 14-10-2018 MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 941 0.0 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 Gene3D G3DSA:1.20.1580.10 92 496 2.3E-240 T 14-10-2018 MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 Gene3D G3DSA:3.40.50.300 8 599 2.3E-240 T 14-10-2018 MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 SUPERFAMILY SSF52540 8 573 1.11E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 Gene3D G3DSA:1.10.8.280 291 407 2.3E-240 T 14-10-2018 MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 Gene3D G3DSA:3.40.50.300 632 952 4.8E-143 T 14-10-2018 MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 956 22.26 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0169 b89fda2a24dd9d8cf7e09e350b1f39dd 957 SUPERFAMILY SSF52540 630 928 4.67E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1006 fcb5f66a665e2d00dd8b54b0cd05892f 391 Pfam PF01595 Domain of unknown function DUF21 41 212 2.2E-25 T 14-10-2018 IPR002550 CNNM, transmembrane domain MCR_1006 fcb5f66a665e2d00dd8b54b0cd05892f 391 SUPERFAMILY SSF54631 218 362 3.07E-23 T 14-10-2018 MCR_1006 fcb5f66a665e2d00dd8b54b0cd05892f 391 Gene3D G3DSA:3.10.580.10 209 361 2.0E-33 T 14-10-2018 MCR_1006 fcb5f66a665e2d00dd8b54b0cd05892f 391 Pfam PF00571 CBS domain 299 349 2.4E-4 T 14-10-2018 IPR000644 CBS domain MCR_0516 d7387d7e19f363d226091372c685c6e6 487 PIRSF PIRSF002457 2 487 2.9E-133 T 14-10-2018 IPR030676 Citrate carrier CitT-related MCR_0516 d7387d7e19f363d226091372c685c6e6 487 Pfam PF00939 Sodium:sulfate symporter transmembrane region 9 487 7.2E-135 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 MCR_0516 d7387d7e19f363d226091372c685c6e6 487 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 24 481 5.6E-116 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 MCR_1266 9cef28c25a7c4be834d2c1fec3f27e12 91 Pfam PF00462 Glutaredoxin 4 65 3.4E-19 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MCR_1266 9cef28c25a7c4be834d2c1fec3f27e12 91 PRINTS PR00160 Glutaredoxin signature 4 22 7.4E-14 T 14-10-2018 IPR014025 Glutaredoxin subgroup MCR_1266 9cef28c25a7c4be834d2c1fec3f27e12 91 PRINTS PR00160 Glutaredoxin signature 62 75 7.4E-14 T 14-10-2018 IPR014025 Glutaredoxin subgroup MCR_1266 9cef28c25a7c4be834d2c1fec3f27e12 91 PRINTS PR00160 Glutaredoxin signature 48 61 7.4E-14 T 14-10-2018 IPR014025 Glutaredoxin subgroup MCR_1266 9cef28c25a7c4be834d2c1fec3f27e12 91 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 14-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 MCR_1266 9cef28c25a7c4be834d2c1fec3f27e12 91 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 84 6.3E-29 T 14-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 MCR_1266 9cef28c25a7c4be834d2c1fec3f27e12 91 SUPERFAMILY SSF52833 3 85 3.56E-26 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_1266 9cef28c25a7c4be834d2c1fec3f27e12 91 Gene3D G3DSA:3.40.30.10 1 86 7.0E-27 T 14-10-2018 MCR_1279 db9b1ed8b8899f635140fa75d6cf06ef 366 SUPERFAMILY SSF101790 275 363 3.92E-21 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal MCR_1279 db9b1ed8b8899f635140fa75d6cf06ef 366 Gene3D G3DSA:3.30.1360.120 8 235 4.5E-75 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MCR_1279 db9b1ed8b8899f635140fa75d6cf06ef 366 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 359 7.8E-123 T 14-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MCR_1279 db9b1ed8b8899f635140fa75d6cf06ef 366 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 258 1.9E-78 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain MCR_1279 db9b1ed8b8899f635140fa75d6cf06ef 366 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 360 41.824 T 14-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MCR_1279 db9b1ed8b8899f635140fa75d6cf06ef 366 SUPERFAMILY SSF103025 5 282 9.76E-86 T 14-10-2018 MCR_1279 db9b1ed8b8899f635140fa75d6cf06ef 366 Gene3D G3DSA:3.30.70.1400 53 142 4.5E-75 T 14-10-2018 MCR_1279 db9b1ed8b8899f635140fa75d6cf06ef 366 Gene3D G3DSA:2.40.30.110 283 366 6.6E-24 T 14-10-2018 MCR_1279 db9b1ed8b8899f635140fa75d6cf06ef 366 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 266 354 1.2E-16 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MCR_1279 db9b1ed8b8899f635140fa75d6cf06ef 366 Gene3D G3DSA:4.10.1250.10 236 279 1.1E-19 T 14-10-2018 MCR_1279 db9b1ed8b8899f635140fa75d6cf06ef 366 PIRSF PIRSF006487 1 365 5.4E-79 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MCR_0497 c6fe85ced86a3d20e2212288868e2c1a 165 SUPERFAMILY SSF54534 13 152 6.68E-36 T 14-10-2018 MCR_0497 c6fe85ced86a3d20e2212288868e2c1a 165 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 12 104 4.1E-14 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MCR_0497 c6fe85ced86a3d20e2212288868e2c1a 165 Gene3D G3DSA:2.40.10.330 81 138 3.4E-38 T 14-10-2018 MCR_0497 c6fe85ced86a3d20e2212288868e2c1a 165 Gene3D G3DSA:3.10.50.40 22 150 3.4E-38 T 14-10-2018 MCR_1827 47f9d719017d46829f79a5772976cd6b 206 SUPERFAMILY SSF52833 22 189 6.75E-41 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_1827 47f9d719017d46829f79a5772976cd6b 206 Pfam PF01323 DSBA-like thioredoxin domain 91 187 7.5E-15 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 MCR_1827 47f9d719017d46829f79a5772976cd6b 206 Gene3D G3DSA:3.40.30.10 23 205 2.0E-49 T 14-10-2018 MCR_1827 47f9d719017d46829f79a5772976cd6b 206 PIRSF PIRSF001488 1 205 1.9E-48 T 14-10-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL MCR_0657 3761628c918baac8df922d8a0bb5a581 192 SUPERFAMILY SSF101874 19 189 1.7E-43 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MCR_0657 3761628c918baac8df922d8a0bb5a581 192 Pfam PF04264 YceI-like domain 21 187 9.3E-35 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MCR_0657 3761628c918baac8df922d8a0bb5a581 192 Gene3D G3DSA:2.40.128.110 18 190 3.4E-41 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MCR_0657 3761628c918baac8df922d8a0bb5a581 192 SMART SM00867 20 188 2.7E-48 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MCR_0306 75057d83ee55a1a4b0d2065f57fc5114 222 Gene3D G3DSA:3.40.50.11690 92 222 7.0E-29 T 14-10-2018 MCR_0306 75057d83ee55a1a4b0d2065f57fc5114 222 Pfam PF03799 Cell division protein FtsQ 97 209 2.6E-14 T 14-10-2018 IPR005548 Cell division protein FtsQ/DivIB MCR_0306 75057d83ee55a1a4b0d2065f57fc5114 222 Pfam PF08478 POTRA domain, FtsQ-type 39 87 1.9E-6 T 14-10-2018 IPR013685 POTRA domain, FtsQ-type MCR_0306 75057d83ee55a1a4b0d2065f57fc5114 222 Gene3D G3DSA:3.10.20.310 23 89 4.5E-9 T 14-10-2018 MCR_1148 44a326b6430da0074ac403e2e52b88d1 540 Gene3D G3DSA:1.20.1250.20 52 267 4.9E-6 T 14-10-2018 MCR_1148 44a326b6430da0074ac403e2e52b88d1 540 Pfam PF07690 Major Facilitator Superfamily 59 328 3.4E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MCR_1148 44a326b6430da0074ac403e2e52b88d1 540 Gene3D G3DSA:1.20.1250.20 344 532 1.5E-7 T 14-10-2018 MCR_1148 44a326b6430da0074ac403e2e52b88d1 540 SUPERFAMILY SSF103473 37 529 2.49E-27 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_1103 5767e0ad469ef3ba77bf8787bbc6d516 383 SUPERFAMILY SSF82689 265 364 1.7E-21 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MCR_1103 5767e0ad469ef3ba77bf8787bbc6d516 383 SUPERFAMILY SSF50182 198 263 1.11E-17 T 14-10-2018 IPR010920 LSM domain superfamily MCR_1103 5767e0ad469ef3ba77bf8787bbc6d516 383 SUPERFAMILY SSF82861 119 196 3.4E-10 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MCR_1103 5767e0ad469ef3ba77bf8787bbc6d516 383 Gene3D G3DSA:3.30.70.100 264 360 1.1E-16 T 14-10-2018 MCR_1103 5767e0ad469ef3ba77bf8787bbc6d516 383 Pfam PF00924 Mechanosensitive ion channel 155 354 2.9E-46 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MCR_1103 5767e0ad469ef3ba77bf8787bbc6d516 383 Gene3D G3DSA:2.30.30.60 214 262 4.0E-13 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MCR_0769 c421d9487dc2af7b6dbb3d0e7dd73b70 264 Pfam PF00899 ThiF family 22 255 1.5E-48 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MCR_0769 c421d9487dc2af7b6dbb3d0e7dd73b70 264 Gene3D G3DSA:3.40.50.720 14 263 4.7E-70 T 14-10-2018 MCR_0769 c421d9487dc2af7b6dbb3d0e7dd73b70 264 SUPERFAMILY SSF69572 7 260 1.96E-66 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MCR_1344 d450760dde9470cd5a24fdf4fac45bc1 101 SUPERFAMILY SSF117991 14 98 9.81E-17 T 14-10-2018 IPR027471 YbeD-like domain superfamily MCR_1344 d450760dde9470cd5a24fdf4fac45bc1 101 Gene3D G3DSA:3.30.70.260 11 101 2.9E-16 T 14-10-2018 MCR_1344 d450760dde9470cd5a24fdf4fac45bc1 101 Pfam PF04359 Protein of unknown function (DUF493) 17 99 3.1E-21 T 14-10-2018 IPR007454 Uncharacterised protein family UPF0250 MCR_1041 25c50001d8718d4fd3626edc29080f85 473 SUPERFAMILY SSF143548 16 153 3.92E-42 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 MCR_1041 25c50001d8718d4fd3626edc29080f85 473 Gene3D G3DSA:3.30.1330.90 10 155 8.5E-50 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 MCR_1041 25c50001d8718d4fd3626edc29080f85 473 Pfam PF03313 Serine dehydratase alpha chain 183 448 7.2E-99 T 14-10-2018 IPR005130 Serine dehydratase-like, alpha subunit MCR_1041 25c50001d8718d4fd3626edc29080f85 473 Pfam PF03315 Serine dehydratase beta chain 3 152 7.7E-53 T 14-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MCR_1041 25c50001d8718d4fd3626edc29080f85 473 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 450 1.4E-201 T 14-10-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MCR_1431 dd83ce3ef1a4cdccc6d560e452cbb54e 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 59 81 2.4E-7 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MCR_1431 dd83ce3ef1a4cdccc6d560e452cbb54e 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 177 196 2.4E-7 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MCR_1431 dd83ce3ef1a4cdccc6d560e452cbb54e 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 197 216 2.4E-7 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MCR_1431 dd83ce3ef1a4cdccc6d560e452cbb54e 257 Pfam PF01061 ABC-2 type transporter 10 219 1.8E-37 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MCR_1431 dd83ce3ef1a4cdccc6d560e452cbb54e 257 PIRSF PIRSF006648 1 254 3.0E-26 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MCR_1355 18f514df29f8c700740c00073505b922 194 Pfam PF00355 Rieske [2Fe-2S] domain 53 179 3.6E-13 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MCR_1355 18f514df29f8c700740c00073505b922 194 Gene3D G3DSA:1.20.5.510 1 41 3.8E-6 T 14-10-2018 MCR_1355 18f514df29f8c700740c00073505b922 194 PRINTS PR00162 Rieske 2Fe-2S subunit signature 152 164 9.5E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MCR_1355 18f514df29f8c700740c00073505b922 194 PRINTS PR00162 Rieske 2Fe-2S subunit signature 120 131 9.5E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MCR_1355 18f514df29f8c700740c00073505b922 194 Gene3D G3DSA:2.102.10.10 44 192 1.9E-44 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MCR_1355 18f514df29f8c700740c00073505b922 194 SUPERFAMILY SSF50022 31 191 4.75E-39 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MCR_1355 18f514df29f8c700740c00073505b922 194 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 1 41 7.6E-16 T 14-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 MCR_1355 18f514df29f8c700740c00073505b922 194 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 10 186 4.6E-64 T 14-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 MCR_0235 6b517734b48c418595f859b7192a746d 274 Gene3D G3DSA:3.20.10.10 136 272 2.7E-24 T 14-10-2018 MCR_0235 6b517734b48c418595f859b7192a746d 274 Gene3D G3DSA:3.30.470.10 14 115 5.5E-16 T 14-10-2018 MCR_0235 6b517734b48c418595f859b7192a746d 274 SUPERFAMILY SSF56752 18 269 5.62E-30 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MCR_0235 6b517734b48c418595f859b7192a746d 274 Pfam PF01063 Amino-transferase class IV 29 260 8.4E-20 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MCR_0643 d515e4b498495e2ed9d05b9361da141c 223 SUPERFAMILY SSF53474 12 222 5.72E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0643 d515e4b498495e2ed9d05b9361da141c 223 Pfam PF02230 Phospholipase/Carboxylesterase 14 220 1.5E-47 T 14-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MCR_0643 d515e4b498495e2ed9d05b9361da141c 223 Gene3D G3DSA:3.40.50.1820 4 219 1.4E-52 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0335 e8ff1c63cf753fa89ecc01189016df6d 349 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 6 343 5.3E-130 T 14-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 MCR_0335 e8ff1c63cf753fa89ecc01189016df6d 349 Gene3D G3DSA:3.40.50.300 104 348 3.0E-90 T 14-10-2018 MCR_0335 e8ff1c63cf753fa89ecc01189016df6d 349 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 200 214 - T 14-10-2018 IPR001482 Type II/IV secretion system protein MCR_0335 e8ff1c63cf753fa89ecc01189016df6d 349 Gene3D G3DSA:3.30.450.90 1 103 5.0E-26 T 14-10-2018 MCR_0335 e8ff1c63cf753fa89ecc01189016df6d 349 SUPERFAMILY SSF52540 9 343 1.2E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0335 e8ff1c63cf753fa89ecc01189016df6d 349 Pfam PF00437 Type II/IV secretion system protein 14 275 1.9E-47 T 14-10-2018 IPR001482 Type II/IV secretion system protein MCR_0335 e8ff1c63cf753fa89ecc01189016df6d 349 SMART SM00382 129 254 0.0034 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1430 53828e30cc9bbd63d2c271f1095ab0b1 280 Pfam PF14489 QueF-like protein 193 265 3.7E-19 T 14-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MCR_1430 53828e30cc9bbd63d2c271f1095ab0b1 280 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 13 126 3.2E-39 T 14-10-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MCR_1430 53828e30cc9bbd63d2c271f1095ab0b1 280 SUPERFAMILY SSF55620 182 264 3.11E-9 T 14-10-2018 MCR_1430 53828e30cc9bbd63d2c271f1095ab0b1 280 Gene3D G3DSA:3.30.1130.10 13 132 4.8E-38 T 14-10-2018 MCR_1430 53828e30cc9bbd63d2c271f1095ab0b1 280 TIGRFAM TIGR03138 QueF: queuine synthase 4 280 1.8E-95 T 14-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MCR_1430 53828e30cc9bbd63d2c271f1095ab0b1 280 Gene3D G3DSA:3.30.1130.10 140 280 1.1E-41 T 14-10-2018 MCR_1430 53828e30cc9bbd63d2c271f1095ab0b1 280 PIRSF PIRSF004750 2 280 9.0E-92 T 14-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 SUPERFAMILY SSF50249 581 680 7.83E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1401 6958de1a20e18c46b0d92458397d368f 683 SUPERFAMILY SSF47323 393 549 7.29E-38 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 Gene3D G3DSA:2.20.28.20 141 175 6.2E-149 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 546 674 1.1E-37 T 14-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 Gene3D G3DSA:3.40.50.620 7 387 6.2E-149 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_1401 6958de1a20e18c46b0d92458397d368f 683 SUPERFAMILY SSF52374 5 390 7.35E-95 T 14-10-2018 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 Hamap MF_00098 Methionine--tRNA ligase [metG]. 5 548 38.538 T 14-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 SUPERFAMILY SSF57770 141 175 3.66E-11 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 Pfam PF09334 tRNA synthetases class I (M) 7 399 5.4E-151 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 25 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 Gene3D G3DSA:2.40.50.140 574 682 5.4E-31 T 14-10-2018 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 Pfam PF01588 Putative tRNA binding domain 588 680 1.1E-24 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 Pfam PF08264 Anticodon-binding domain of tRNA 430 504 4.0E-7 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 Gene3D G3DSA:1.10.730.10 392 529 4.9E-29 T 14-10-2018 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 7 538 1.5E-168 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 4.3E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 255 266 4.3E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 4.3E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 387 398 4.3E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 4.3E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MCR_1401 6958de1a20e18c46b0d92458397d368f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 294 309 4.3E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MCR_0462 6aad16e1613b82c2575a8a8536ce4205 298 SUPERFAMILY SSF54637 187 294 1.74E-18 T 14-10-2018 IPR029069 HotDog domain superfamily MCR_0462 6aad16e1613b82c2575a8a8536ce4205 298 Gene3D G3DSA:3.10.129.10 33 296 1.8E-65 T 14-10-2018 MCR_0462 6aad16e1613b82c2575a8a8536ce4205 298 Pfam PF01575 MaoC like domain 191 267 4.8E-15 T 14-10-2018 IPR002539 MaoC-like dehydratase domain MCR_0462 6aad16e1613b82c2575a8a8536ce4205 298 SUPERFAMILY SSF54637 62 156 5.22E-7 T 14-10-2018 IPR029069 HotDog domain superfamily MCR_0377 1d535b4c01634bb8d500df169007b87c 81 Gene3D G3DSA:1.20.20.10 1 78 5.0E-28 T 14-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0377 1d535b4c01634bb8d500df169007b87c 81 Pfam PF00137 ATP synthase subunit C 11 74 1.1E-9 T 14-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MCR_0377 1d535b4c01634bb8d500df169007b87c 81 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 14-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0377 1d535b4c01634bb8d500df169007b87c 81 PRINTS PR00124 ATP synthase C subunit signature 12 31 4.7E-7 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0377 1d535b4c01634bb8d500df169007b87c 81 PRINTS PR00124 ATP synthase C subunit signature 33 48 4.7E-7 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0377 1d535b4c01634bb8d500df169007b87c 81 PRINTS PR00124 ATP synthase C subunit signature 50 75 4.7E-7 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0377 1d535b4c01634bb8d500df169007b87c 81 Hamap MF_01396 ATP synthase subunit c [atpH]. 10 75 13.958 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0377 1d535b4c01634bb8d500df169007b87c 81 SUPERFAMILY SSF81333 4 79 1.1E-18 T 14-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily MCR_0377 1d535b4c01634bb8d500df169007b87c 81 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 21 77 1.3E-28 T 14-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MCR_1297 8e1f4a495dd489a721ca3390abef6d98 347 SUPERFAMILY SSF48019 221 337 1.36E-21 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MCR_1297 8e1f4a495dd489a721ca3390abef6d98 347 SUPERFAMILY SSF52540 18 194 5.31E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1297 8e1f4a495dd489a721ca3390abef6d98 347 Gene3D G3DSA:3.40.50.300 9 142 7.2E-13 T 14-10-2018 MCR_1297 8e1f4a495dd489a721ca3390abef6d98 347 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 60 334 1.1E-32 T 14-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 MCR_1297 8e1f4a495dd489a721ca3390abef6d98 347 Pfam PF06144 DNA polymerase III, delta subunit 58 191 9.0E-9 T 14-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 MCR_1297 8e1f4a495dd489a721ca3390abef6d98 347 Gene3D G3DSA:1.20.272.10 223 341 1.9E-19 T 14-10-2018 MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 PRINTS PR00149 Fumarate lyase superfamily signature 250 277 2.2E-17 T 14-10-2018 IPR000362 Fumarate lyase family MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 PRINTS PR00149 Fumarate lyase superfamily signature 293 309 2.2E-17 T 14-10-2018 IPR000362 Fumarate lyase family MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 2.2E-17 T 14-10-2018 IPR000362 Fumarate lyase family MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 PRINTS PR00149 Fumarate lyase superfamily signature 162 180 2.2E-17 T 14-10-2018 IPR000362 Fumarate lyase family MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 ProSitePatterns PS00163 Fumarate lyases signature. 293 302 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 Gene3D G3DSA:1.10.40.30 381 447 2.5E-148 T 14-10-2018 MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 Gene3D G3DSA:1.20.200.10 118 448 2.5E-148 T 14-10-2018 MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 Pfam PF00206 Lyase 14 311 1.0E-64 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 SUPERFAMILY SSF48557 4 449 2.36E-104 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 455 2.6E-132 T 14-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 Gene3D G3DSA:1.10.275.10 1 117 1.1E-47 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal MCR_0594 f3679c7e7df1e358c183163e764a3f23 462 Pfam PF08328 Adenylosuccinate lyase C-terminal 330 447 3.8E-46 T 14-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 MCR_0086 ef3c85d1125084d314f9d4b0cfbd872a 203 Hamap MF_01405 dITP/XTP pyrophosphatase. 2 199 46.308 T 14-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 MCR_0086 ef3c85d1125084d314f9d4b0cfbd872a 203 Pfam PF01725 Ham1 family 5 194 1.2E-51 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 MCR_0086 ef3c85d1125084d314f9d4b0cfbd872a 203 Gene3D G3DSA:3.90.950.10 1 201 1.2E-69 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MCR_0086 ef3c85d1125084d314f9d4b0cfbd872a 203 SUPERFAMILY SSF52972 1 199 9.42E-65 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MCR_0086 ef3c85d1125084d314f9d4b0cfbd872a 203 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 197 7.1E-49 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 MCR_1289 bed853be04503befd8f5a1290f72cbb3 398 ProSitePatterns PS01215 Mrp family signature. 248 264 - T 14-10-2018 IPR000808 Mrp, conserved site GO:0005524 MCR_1289 bed853be04503befd8f5a1290f72cbb3 398 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 141 379 2.1E-97 T 14-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 MCR_1289 bed853be04503befd8f5a1290f72cbb3 398 Gene3D G3DSA:3.40.50.300 127 377 1.1E-81 T 14-10-2018 MCR_1289 bed853be04503befd8f5a1290f72cbb3 398 Hamap MF_02040 Iron-sulfur cluster carrier protein. 133 383 35.699 T 14-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein MCR_1289 bed853be04503befd8f5a1290f72cbb3 398 SUPERFAMILY SSF52540 135 362 6.39E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0366 534746fdb8cfa12a258417ac1df5e089 180 Pfam PF13505 Outer membrane protein beta-barrel domain 14 167 1.0E-18 T 14-10-2018 IPR027385 Outer membrane protein beta-barrel MCR_0366 534746fdb8cfa12a258417ac1df5e089 180 SUPERFAMILY SSF56925 33 175 2.62E-20 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MCR_0366 534746fdb8cfa12a258417ac1df5e089 180 Gene3D G3DSA:2.40.160.20 29 180 1.3E-22 T 14-10-2018 MCR_1551 9ec80098a270b852a97ffb1d2eaab518 165 Pfam PF04972 BON domain 42 107 2.1E-8 T 14-10-2018 IPR007055 BON domain MCR_1551 9ec80098a270b852a97ffb1d2eaab518 165 Pfam PF01476 LysM domain 116 164 7.6E-13 T 14-10-2018 IPR018392 LysM domain MCR_1551 9ec80098a270b852a97ffb1d2eaab518 165 Gene3D G3DSA:3.10.350.10 115 163 2.4E-15 T 14-10-2018 IPR036779 LysM domain superfamily MCR_1551 9ec80098a270b852a97ffb1d2eaab518 165 SMART SM00257 115 164 1.3E-13 T 14-10-2018 IPR018392 LysM domain MCR_1551 9ec80098a270b852a97ffb1d2eaab518 165 SUPERFAMILY SSF54106 114 164 4.32E-8 T 14-10-2018 MCR_0292 cf8c77f7ee07b0c04500a898fd02a767 66 Gene3D G3DSA:1.10.10.600 1 66 1.9E-27 T 14-10-2018 IPR036762 IscX-like superfamily MCR_0292 cf8c77f7ee07b0c04500a898fd02a767 66 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 5 65 1.1E-31 T 14-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 MCR_0292 cf8c77f7ee07b0c04500a898fd02a767 66 Pfam PF04384 Iron-sulphur cluster assembly 4 65 4.4E-30 T 14-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 MCR_0292 cf8c77f7ee07b0c04500a898fd02a767 66 PIRSF PIRSF039003 4 66 2.7E-32 T 14-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 MCR_0292 cf8c77f7ee07b0c04500a898fd02a767 66 SUPERFAMILY SSF140319 4 65 1.57E-25 T 14-10-2018 IPR036762 IscX-like superfamily MCR_0772 1648eab8e16dadcd8d5597f89673423e 336 Pfam PF04829 Pre-toxin domain with VENN motif 10 56 3.3E-8 T 14-10-2018 IPR006914 VENN motif-containing domain MCR_0607 74eb4813398761418da2eb0fe2b3462e 127 Gene3D G3DSA:3.90.1010.10 1 127 2.2E-58 T 14-10-2018 MCR_0607 74eb4813398761418da2eb0fe2b3462e 127 Pfam PF01592 NifU-like N terminal domain 2 125 2.1E-56 T 14-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 MCR_0607 74eb4813398761418da2eb0fe2b3462e 127 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 1.2E-68 T 14-10-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 MCR_0607 74eb4813398761418da2eb0fe2b3462e 127 SUPERFAMILY SSF82649 1 124 2.51E-48 T 14-10-2018 MCR_0429 ba7b6d2930306ba8dc816e93b85876fd 356 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 19 336 8.9E-129 T 14-10-2018 IPR022462 Lysine-2,3-aminomutase-like MCR_0429 ba7b6d2930306ba8dc816e93b85876fd 356 TIGRFAM TIGR00238 TIGR00238: KamA family protein 12 327 1.6E-99 T 14-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase MCR_0429 ba7b6d2930306ba8dc816e93b85876fd 356 Pfam PF04055 Radical SAM superfamily 116 233 2.5E-9 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MCR_0429 ba7b6d2930306ba8dc816e93b85876fd 356 PIRSF PIRSF004911 2 355 2.8E-111 T 14-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase MCR_0429 ba7b6d2930306ba8dc816e93b85876fd 356 Pfam PF13394 4Fe-4S single cluster domain 118 196 9.0E-9 T 14-10-2018 MCR_0429 ba7b6d2930306ba8dc816e93b85876fd 356 Gene3D G3DSA:3.20.20.70 51 335 3.4E-91 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0429 ba7b6d2930306ba8dc816e93b85876fd 356 SUPERFAMILY SSF102114 103 340 1.23E-24 T 14-10-2018 MCR_1118 676bc901e3e74f215931b474820a0118 158 SUPERFAMILY SSF54534 82 157 1.68E-23 T 14-10-2018 MCR_1118 676bc901e3e74f215931b474820a0118 158 SUPERFAMILY SSF46557 3 77 8.11E-29 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MCR_1118 676bc901e3e74f215931b474820a0118 158 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 2.4E-32 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MCR_1118 676bc901e3e74f215931b474820a0118 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 32.51 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MCR_1118 676bc901e3e74f215931b474820a0118 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 1.1E-26 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MCR_1118 676bc901e3e74f215931b474820a0118 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 1.4E-57 T 14-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 MCR_1118 676bc901e3e74f215931b474820a0118 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MCR_1118 676bc901e3e74f215931b474820a0118 158 PIRSF PIRSF006092 1 158 1.2E-53 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MCR_1118 676bc901e3e74f215931b474820a0118 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MCR_1118 676bc901e3e74f215931b474820a0118 158 Gene3D G3DSA:3.10.50.30 76 158 1.8E-28 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 MCR_1118 676bc901e3e74f215931b474820a0118 158 Gene3D G3DSA:1.10.287.180 1 75 9.9E-32 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 Gene3D G3DSA:3.30.70.870 294 375 3.0E-35 T 14-10-2018 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 Gene3D G3DSA:2.40.30.10 194 293 6.8E-33 T 14-10-2018 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 Hamap MF_00071 Elongation factor 4 [lepA]. 1 604 292.14 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 TIGRFAM TIGR01393 lepA: elongation factor 4 11 603 3.7E-290 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 Gene3D G3DSA:3.40.50.300 8 193 1.4E-68 T 14-10-2018 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 Pfam PF00009 Elongation factor Tu GTP binding domain 11 189 2.5E-50 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 SUPERFAMILY SSF52540 5 231 6.5E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1704 6f24ad534de19b8198956d46d62012b1 604 Pfam PF00679 Elongation factor G C-terminus 408 485 1.9E-17 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MCR_1704 6f24ad534de19b8198956d46d62012b1 604 SUPERFAMILY SSF54980 300 378 2.41E-19 T 14-10-2018 IPR035647 EF-G domain III/V-like MCR_1704 6f24ad534de19b8198956d46d62012b1 604 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 50 65 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MCR_1704 6f24ad534de19b8198956d46d62012b1 604 Gene3D G3DSA:3.30.70.2570 487 561 5.2E-34 T 14-10-2018 IPR038363 LepA, C-terminal domain superfamily MCR_1704 6f24ad534de19b8198956d46d62012b1 604 PRINTS PR00315 GTP-binding elongation factor signature 134 143 9.0E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 PRINTS PR00315 GTP-binding elongation factor signature 82 92 9.0E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 PRINTS PR00315 GTP-binding elongation factor signature 57 65 9.0E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 PRINTS PR00315 GTP-binding elongation factor signature 14 27 9.0E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 PRINTS PR00315 GTP-binding elongation factor signature 98 109 9.0E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 SMART SM00838 409 493 0.0072 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MCR_1704 6f24ad534de19b8198956d46d62012b1 604 Pfam PF06421 GTP-binding protein LepA C-terminus 495 601 6.5E-51 T 14-10-2018 IPR013842 GTP-binding protein LepA, C-terminal MCR_1704 6f24ad534de19b8198956d46d62012b1 604 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 180 1.3E-17 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 Pfam PF03144 Elongation factor Tu domain 2 213 283 8.9E-10 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MCR_1704 6f24ad534de19b8198956d46d62012b1 604 SUPERFAMILY SSF54980 408 501 1.77E-22 T 14-10-2018 IPR035647 EF-G domain III/V-like MCR_1704 6f24ad534de19b8198956d46d62012b1 604 Gene3D G3DSA:3.30.70.3380 376 486 8.2E-36 T 14-10-2018 MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 Gene3D G3DSA:2.40.30.10 129 268 3.4E-52 T 14-10-2018 MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 Pfam PF00175 Oxidoreductase NAD-binding domain 281 390 3.0E-16 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 9 411 3.0E-221 T 14-10-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 PIRSF PIRSF000044 2 411 9.0E-221 T 14-10-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 Gene3D G3DSA:3.10.20.30 37 128 1.2E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 Gene3D G3DSA:3.40.50.80 279 396 3.0E-31 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 4 411 63.523 T 14-10-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 48 118 1.3E-10 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 Pfam PF00970 Oxidoreductase FAD-binding domain 206 270 9.2E-11 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 SUPERFAMILY SSF63380 108 276 2.04E-35 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 SUPERFAMILY SSF54292 38 125 4.41E-21 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MCR_1463 fe2b394f097cb08ac539c08139dce6bf 411 SUPERFAMILY SSF52343 259 406 6.55E-37 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MCR_1242 0c4026406ccdd4eaf08d06dcc26bee0c 329 PIRSF PIRSF500176 4 325 3.8E-41 T 14-10-2018 MCR_1242 0c4026406ccdd4eaf08d06dcc26bee0c 329 PIRSF PIRSF001220 3 323 4.1E-33 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MCR_1242 0c4026406ccdd4eaf08d06dcc26bee0c 329 PRINTS PR00139 Asparaginase/glutaminase family signature 82 100 1.7E-7 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MCR_1242 0c4026406ccdd4eaf08d06dcc26bee0c 329 PRINTS PR00139 Asparaginase/glutaminase family signature 264 282 1.7E-7 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MCR_1242 0c4026406ccdd4eaf08d06dcc26bee0c 329 PRINTS PR00139 Asparaginase/glutaminase family signature 8 19 1.7E-7 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MCR_1242 0c4026406ccdd4eaf08d06dcc26bee0c 329 Gene3D G3DSA:3.40.50.1170 4 215 4.6E-31 T 14-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 MCR_1242 0c4026406ccdd4eaf08d06dcc26bee0c 329 SMART SM00870 7 327 8.8E-24 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MCR_1242 0c4026406ccdd4eaf08d06dcc26bee0c 329 SUPERFAMILY SSF53774 7 315 1.83E-47 T 14-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 MCR_1242 0c4026406ccdd4eaf08d06dcc26bee0c 329 Pfam PF00710 Asparaginase, N-terminal 8 180 4.1E-30 T 14-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MCR_1242 0c4026406ccdd4eaf08d06dcc26bee0c 329 Gene3D G3DSA:3.40.50.40 216 323 1.3E-18 T 14-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 MCR_0641 68290657abd8895d13af56db248f6719 291 SUPERFAMILY SSF52540 53 192 3.81E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0641 68290657abd8895d13af56db248f6719 291 Pfam PF05673 Protein of unknown function (DUF815) 29 282 9.5E-93 T 14-10-2018 IPR008533 Domain of unknown function DUF815 MCR_0641 68290657abd8895d13af56db248f6719 291 Gene3D G3DSA:3.40.50.300 50 196 1.5E-10 T 14-10-2018 MCR_1859 b4709a650b30934fc3e6001defb3b2ad 202 SUPERFAMILY SSF53474 3 195 4.54E-11 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_1859 b4709a650b30934fc3e6001defb3b2ad 202 Pfam PF05728 Uncharacterised protein family (UPF0227) 2 194 3.4E-29 T 14-10-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA MCR_1859 b4709a650b30934fc3e6001defb3b2ad 202 Gene3D G3DSA:3.40.50.1820 1 201 3.2E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_1100 f7fd3c62f914f29f854498f0e955dc20 176 Gene3D G3DSA:3.40.50.9100 4 162 1.0E-59 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MCR_1100 f7fd3c62f914f29f854498f0e955dc20 176 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 15 158 8.0E-55 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MCR_1100 f7fd3c62f914f29f854498f0e955dc20 176 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 176 64.585 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MCR_1100 f7fd3c62f914f29f854498f0e955dc20 176 ProSitePatterns PS01029 Dehydroquinase class II signature. 19 36 - T 14-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MCR_1100 f7fd3c62f914f29f854498f0e955dc20 176 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 154 1.0E-47 T 14-10-2018 MCR_1100 f7fd3c62f914f29f854498f0e955dc20 176 Pfam PF01220 Dehydroquinase class II 15 155 8.9E-58 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MCR_1100 f7fd3c62f914f29f854498f0e955dc20 176 SUPERFAMILY SSF52304 15 161 6.41E-58 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MCR_1100 f7fd3c62f914f29f854498f0e955dc20 176 PIRSF PIRSF001399 12 162 2.4E-57 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 PIRSF PIRSF000497 1 386 2.0E-170 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 234 375 1.1E-65 T 14-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 260 268 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 Gene3D G3DSA:3.30.300.10 11 271 2.1E-173 T 14-10-2018 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 SUPERFAMILY SSF55973 234 384 2.75E-66 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 385 3.2E-185 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 SUPERFAMILY SSF55973 112 233 7.85E-50 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 SUPERFAMILY SSF55973 5 110 5.1E-45 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 386 56.511 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 116 126 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 Gene3D G3DSA:3.30.300.10 5 234 2.1E-173 T 14-10-2018 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 101 1.6E-41 T 14-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 Pfam PF02772 S-adenosylmethionine synthetase, central domain 114 232 1.7E-45 T 14-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MCR_0654 8afaa1b6758b1aeb19f73229546e5c5d 386 Gene3D G3DSA:3.30.300.10 102 378 2.1E-173 T 14-10-2018 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 PRINTS PR00834 HtrA/DegQ protease family signature 162 182 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 PRINTS PR00834 HtrA/DegQ protease family signature 141 153 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 PRINTS PR00834 HtrA/DegQ protease family signature 201 225 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 PRINTS PR00834 HtrA/DegQ protease family signature 341 353 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 PRINTS PR00834 HtrA/DegQ protease family signature 236 253 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 PRINTS PR00834 HtrA/DegQ protease family signature 258 275 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 Pfam PF13180 PDZ domain 305 391 1.3E-14 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 SMART SM00228 304 383 1.6E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 Gene3D G3DSA:2.40.10.120 80 297 6.8E-71 T 14-10-2018 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 SUPERFAMILY SSF50156 262 382 2.89E-21 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 Pfam PF13365 Trypsin-like peptidase domain 132 265 1.2E-30 T 14-10-2018 MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 SUPERFAMILY SSF50494 79 301 8.55E-60 T 14-10-2018 IPR009003 Peptidase S1, PA clan MCR_1217 bc30d70c0ba3bfa568d589de12f42e28 433 Gene3D G3DSA:2.30.42.10 300 407 2.8E-22 T 14-10-2018 MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 Pfam PF02357 Transcription termination factor nusG 1 106 3.4E-26 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 Gene3D G3DSA:2.30.30.30 117 175 2.2E-20 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 SUPERFAMILY SSF82679 1 111 2.09E-35 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 SUPERFAMILY SSF50104 119 175 3.14E-16 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 SMART SM00739 121 148 2.6E-5 T 14-10-2018 IPR005824 KOW MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 PRINTS PR00338 Transcription termination factor NUSG signature 151 167 1.1E-14 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 PRINTS PR00338 Transcription termination factor NUSG signature 133 148 1.1E-14 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 PRINTS PR00338 Transcription termination factor NUSG signature 55 67 1.1E-14 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 1 175 21.034 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 Pfam PF00467 KOW motif 124 156 1.3E-7 T 14-10-2018 IPR005824 KOW MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 SMART SM00738 1 109 1.9E-36 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 3 175 3.4E-60 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MCR_0252 2a3dab9dc2c69c22f7b9e02cfdf5535a 176 Gene3D G3DSA:3.30.70.940 1 116 8.5E-43 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MCR_0815 235be8a02a1b24e5151d78a2809b66ba 261 Pfam PF13614 AAA domain 1 180 6.4E-54 T 14-10-2018 IPR025669 AAA domain MCR_0815 235be8a02a1b24e5151d78a2809b66ba 261 PIRSF PIRSF009320 96 261 1.3E-9 T 14-10-2018 MCR_0815 235be8a02a1b24e5151d78a2809b66ba 261 PIRSF PIRSF009320 1 77 7.3E-15 T 14-10-2018 MCR_0815 235be8a02a1b24e5151d78a2809b66ba 261 Gene3D G3DSA:3.40.50.300 1 260 1.3E-75 T 14-10-2018 MCR_0815 235be8a02a1b24e5151d78a2809b66ba 261 SUPERFAMILY SSF52540 1 255 2.11E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 SUPERFAMILY SSF53474 585 828 5.13E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 678 708 - T 14-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 Gene3D G3DSA:3.40.50.1820 164 831 7.0E-138 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 SUPERFAMILY SSF50993 165 572 1.49E-24 T 14-10-2018 MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 757 772 1.3E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 701 721 1.3E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 617 635 1.3E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 643 667 1.3E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 776 798 1.3E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 671 690 1.3E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 Gene3D G3DSA:2.130.10.120 204 576 7.0E-138 T 14-10-2018 MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 164 568 3.1E-18 T 14-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MCR_0081 5c00d125bac59edeb46339accaa2ce30 895 Pfam PF00326 Prolyl oligopeptidase family 637 847 7.7E-51 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MCR_0222 77bc6beee45bb4883b0d8455012f27b5 598 Pfam PF16188 C-terminal region of peptidase_M24 539 598 1.1E-20 T 14-10-2018 IPR032416 Peptidase M24, C-terminal domain MCR_0222 77bc6beee45bb4883b0d8455012f27b5 598 Pfam PF00557 Metallopeptidase family M24 311 528 1.9E-42 T 14-10-2018 IPR000994 Peptidase M24 MCR_0222 77bc6beee45bb4883b0d8455012f27b5 598 Gene3D G3DSA:3.40.350.10 152 301 8.3E-38 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MCR_0222 77bc6beee45bb4883b0d8455012f27b5 598 Gene3D G3DSA:3.90.230.10 303 598 4.0E-93 T 14-10-2018 MCR_0222 77bc6beee45bb4883b0d8455012f27b5 598 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 140 2.3E-13 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 MCR_0222 77bc6beee45bb4883b0d8455012f27b5 598 SUPERFAMILY SSF53092 171 294 1.45E-5 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MCR_0222 77bc6beee45bb4883b0d8455012f27b5 598 Gene3D G3DSA:3.40.350.10 2 151 7.9E-39 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MCR_0222 77bc6beee45bb4883b0d8455012f27b5 598 SUPERFAMILY SSF53092 5 138 5.41E-12 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MCR_0222 77bc6beee45bb4883b0d8455012f27b5 598 SUPERFAMILY SSF55920 306 564 3.93E-53 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like MCR_0222 77bc6beee45bb4883b0d8455012f27b5 598 Pfam PF16189 Creatinase/Prolidase N-terminal domain 153 308 5.4E-43 T 14-10-2018 MCR_0115 979a17c3660f70904e0633761189e2d6 443 Gene3D G3DSA:3.40.1160.10 15 296 3.8E-85 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MCR_0115 979a17c3660f70904e0633761189e2d6 443 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 443 190.874 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MCR_0115 979a17c3660f70904e0633761189e2d6 443 Gene3D G3DSA:3.40.630.30 297 443 1.3E-36 T 14-10-2018 MCR_0115 979a17c3660f70904e0633761189e2d6 443 SUPERFAMILY SSF53633 13 297 5.59E-67 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MCR_0115 979a17c3660f70904e0633761189e2d6 443 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 16 442 3.4E-171 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MCR_0115 979a17c3660f70904e0633761189e2d6 443 Pfam PF00696 Amino acid kinase family 32 271 6.2E-21 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MCR_0115 979a17c3660f70904e0633761189e2d6 443 SUPERFAMILY SSF55729 299 421 1.48E-17 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MCR_0115 979a17c3660f70904e0633761189e2d6 443 PIRSF PIRSF000423 6 443 5.1E-178 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MCR_0115 979a17c3660f70904e0633761189e2d6 443 Pfam PF00583 Acetyltransferase (GNAT) family 329 400 5.7E-9 T 14-10-2018 IPR000182 GNAT domain MCR_0337 a60069d90118b8b5c85a0ab8326166fc 563 Pfam PF00795 Carbon-nitrogen hydrolase 29 263 1.3E-28 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MCR_0337 a60069d90118b8b5c85a0ab8326166fc 563 SUPERFAMILY SSF52402 281 544 5.51E-75 T 14-10-2018 MCR_0337 a60069d90118b8b5c85a0ab8326166fc 563 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 26 561 28.142 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MCR_0337 a60069d90118b8b5c85a0ab8326166fc 563 SUPERFAMILY SSF56317 24 264 1.44E-59 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MCR_0337 a60069d90118b8b5c85a0ab8326166fc 563 Gene3D G3DSA:3.60.110.10 16 280 3.0E-87 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MCR_0337 a60069d90118b8b5c85a0ab8326166fc 563 TIGRFAM TIGR00552 nadE: NAD+ synthetase 290 535 7.7E-57 T 14-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 MCR_0337 a60069d90118b8b5c85a0ab8326166fc 563 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 58 73 - T 14-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 MCR_0337 a60069d90118b8b5c85a0ab8326166fc 563 Gene3D G3DSA:3.40.50.620 283 562 3.6E-110 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0337 a60069d90118b8b5c85a0ab8326166fc 563 Pfam PF02540 NAD synthase 286 535 3.4E-70 T 14-10-2018 IPR022310 NAD/GMP synthase MCR_0337 a60069d90118b8b5c85a0ab8326166fc 563 PIRSF PIRSF006630 23 562 5.7E-189 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 SMART SM01130 11 299 1.0E-134 T 14-10-2018 IPR002220 DapA-like GO:0016829 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 45 66 3.2E-33 T 14-10-2018 IPR002220 DapA-like GO:0016829 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 3.2E-33 T 14-10-2018 IPR002220 DapA-like GO:0016829 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 81 99 3.2E-33 T 14-10-2018 IPR002220 DapA-like GO:0016829 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 113 129 3.2E-33 T 14-10-2018 IPR002220 DapA-like GO:0016829 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 PIRSF PIRSF001365 9 301 2.5E-87 T 14-10-2018 IPR002220 DapA-like GO:0016829 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 297 4.6E-105 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 SUPERFAMILY SSF51569 12 299 2.51E-100 T 14-10-2018 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 48 65 - T 14-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 Gene3D G3DSA:3.20.20.70 12 301 3.2E-106 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 11 297 62.368 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 143 173 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 MCR_0238 e3ed639fd07719966bc7a30691827c47 301 Pfam PF00701 Dihydrodipicolinate synthetase family 12 297 6.6E-98 T 14-10-2018 IPR002220 DapA-like GO:0016829 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 619 37.433 T 14-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 Pfam PF00012 Hsp70 protein 22 601 6.1E-159 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 616 9.3E-243 T 14-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 Gene3D G3DSA:2.60.34.10 382 519 2.0E-47 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 Gene3D G3DSA:3.90.640.10 237 315 2.7E-105 T 14-10-2018 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 SUPERFAMILY SSF53067 200 380 5.56E-49 T 14-10-2018 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 SUPERFAMILY SSF100920 387 539 8.37E-47 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 PRINTS PR00301 70kDa heat shock protein signature 388 407 8.2E-53 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 PRINTS PR00301 70kDa heat shock protein signature 150 170 8.2E-53 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 PRINTS PR00301 70kDa heat shock protein signature 469 485 8.2E-53 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 PRINTS PR00301 70kDa heat shock protein signature 210 220 8.2E-53 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 PRINTS PR00301 70kDa heat shock protein signature 364 384 8.2E-53 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 PRINTS PR00301 70kDa heat shock protein signature 20 33 8.2E-53 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 PRINTS PR00301 70kDa heat shock protein signature 333 349 8.2E-53 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 SUPERFAMILY SSF53067 19 195 3.3E-46 T 14-10-2018 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 SUPERFAMILY SSF100934 507 616 9.61E-27 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 Gene3D G3DSA:3.30.420.40 22 377 2.7E-105 T 14-10-2018 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 Gene3D G3DSA:3.30.420.40 192 365 2.7E-105 T 14-10-2018 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 Gene3D G3DSA:1.20.1270.10 523 618 1.4E-21 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MCR_0604 ade846be46859b39d3e8a5ab0bdd5d5e 619 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 204 217 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MCR_0397 edde73e0f3da6f6761a1863c5e78c74a 354 TIGRFAM TIGR01227 hutG: formimidoylglutamase 19 340 2.4E-79 T 14-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 MCR_0397 edde73e0f3da6f6761a1863c5e78c74a 354 PIRSF PIRSF036979 32 348 7.9E-28 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_0397 edde73e0f3da6f6761a1863c5e78c74a 354 PRINTS PR00116 Arginase signature 268 297 7.1E-5 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_0397 edde73e0f3da6f6761a1863c5e78c74a 354 PRINTS PR00116 Arginase signature 148 163 7.1E-5 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_0397 edde73e0f3da6f6761a1863c5e78c74a 354 PRINTS PR00116 Arginase signature 303 317 7.1E-5 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_0397 edde73e0f3da6f6761a1863c5e78c74a 354 SUPERFAMILY SSF52768 17 342 2.16E-70 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily MCR_0397 edde73e0f3da6f6761a1863c5e78c74a 354 Gene3D G3DSA:3.40.800.10 8 350 1.9E-97 T 14-10-2018 MCR_0397 edde73e0f3da6f6761a1863c5e78c74a 354 Pfam PF00491 Arginase family 53 338 4.4E-54 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MCR_0397 edde73e0f3da6f6761a1863c5e78c74a 354 Hamap MF_00737 Formimidoylglutamase [hutG]. 11 342 35.538 T 14-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 198 2.6E-78 T 14-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 SUPERFAMILY SSF52402 191 414 1.23E-57 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 Pfam PF02540 NAD synthase 212 283 2.7E-8 T 14-10-2018 IPR022310 NAD/GMP synthase MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 Gene3D G3DSA:3.40.50.620 202 399 6.5E-77 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 Pfam PF00117 Glutamine amidotransferase class-I 11 192 8.2E-41 T 14-10-2018 IPR017926 Glutamine amidotransferase MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 519 55.417 T 14-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 Gene3D G3DSA:3.40.50.880 8 199 1.5E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 5.1E-5 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 5.1E-5 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 5.1E-5 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 SUPERFAMILY SSF54810 399 519 1.09E-47 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 PRINTS PR00097 Anthranilate synthase component II signature 171 184 1.5E-6 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 PRINTS PR00097 Anthranilate synthase component II signature 53 62 1.5E-6 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 PRINTS PR00097 Anthranilate synthase component II signature 80 91 1.5E-6 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 PRINTS PR00096 Glutamine amidotransferase superfamily signature 171 184 9.8E-8 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 9.8E-8 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 9.8E-8 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 206 519 3.8E-146 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 Gene3D G3DSA:3.30.300.10 400 519 4.4E-49 T 14-10-2018 MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 SUPERFAMILY SSF52317 5 231 1.83E-55 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_0006 96bddef4f15d40062d1b0e005eb219c9 519 Pfam PF00958 GMP synthase C terminal domain 427 518 1.4E-40 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MCR_0703 13e08dd2e3bf3f54e1207b5aa1ac6483 222 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 27 222 27.772 T 14-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 MCR_0703 13e08dd2e3bf3f54e1207b5aa1ac6483 222 Gene3D G3DSA:2.50.20.10 42 221 3.4E-53 T 14-10-2018 MCR_0703 13e08dd2e3bf3f54e1207b5aa1ac6483 222 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 53 212 1.5E-42 T 14-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like MCR_0703 13e08dd2e3bf3f54e1207b5aa1ac6483 222 SUPERFAMILY SSF89392 44 222 4.71E-47 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MCR_0703 13e08dd2e3bf3f54e1207b5aa1ac6483 222 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 24 222 6.0E-27 T 14-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 MCR_0922 b9ce7d56fafd0eda6c5b7ff758e451dd 197 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 98 177 1.3E-33 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MCR_0922 b9ce7d56fafd0eda6c5b7ff758e451dd 197 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 148 154 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MCR_0922 b9ce7d56fafd0eda6c5b7ff758e451dd 197 Gene3D G3DSA:1.10.10.10 97 181 2.9E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0922 b9ce7d56fafd0eda6c5b7ff758e451dd 197 Gene3D G3DSA:3.30.160.70 18 93 4.7E-10 T 14-10-2018 MCR_0922 b9ce7d56fafd0eda6c5b7ff758e451dd 197 SUPERFAMILY SSF46767 97 178 3.53E-28 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 MCR_0922 b9ce7d56fafd0eda6c5b7ff758e451dd 197 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 99 177 1.3E-28 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MCR_0922 b9ce7d56fafd0eda6c5b7ff758e451dd 197 SUPERFAMILY SSF53155 22 103 2.75E-8 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MCR_0716 81c21b78a24494f94cb3430c03e568a8 182 Gene3D G3DSA:3.30.70.3270 35 177 4.4E-43 T 14-10-2018 MCR_0716 81c21b78a24494f94cb3430c03e568a8 182 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MCR_0716 81c21b78a24494f94cb3430c03e568a8 182 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 9 165 27.109 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0716 81c21b78a24494f94cb3430c03e568a8 182 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MCR_0716 81c21b78a24494f94cb3430c03e568a8 182 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 18 139 4.3E-49 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0716 81c21b78a24494f94cb3430c03e568a8 182 SUPERFAMILY SSF54862 35 160 3.56E-28 T 14-10-2018 MCR_0716 81c21b78a24494f94cb3430c03e568a8 182 Pfam PF12838 4Fe-4S dicluster domain 61 115 8.8E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MCR_0701 108920e37f4f3aa45b6de6e04bb0c33e 211 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 32 117 4.1E-22 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MCR_0701 108920e37f4f3aa45b6de6e04bb0c33e 211 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 9 211 36.222 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MCR_0701 108920e37f4f3aa45b6de6e04bb0c33e 211 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 171 211 4.4E-15 T 14-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MCR_0701 108920e37f4f3aa45b6de6e04bb0c33e 211 Gene3D G3DSA:2.30.110.10 2 211 3.1E-75 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MCR_0701 108920e37f4f3aa45b6de6e04bb0c33e 211 PIRSF PIRSF000190 1 211 3.3E-72 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MCR_0701 108920e37f4f3aa45b6de6e04bb0c33e 211 SUPERFAMILY SSF50475 8 211 2.81E-60 T 14-10-2018 MCR_0701 108920e37f4f3aa45b6de6e04bb0c33e 211 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 181 194 - T 14-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MCR_0701 108920e37f4f3aa45b6de6e04bb0c33e 211 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 1 211 6.1E-80 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MCR_1869 253308088b7e169231ab3d8f4408b216 280 Pfam PF00950 ABC 3 transport family 11 265 1.8E-86 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MCR_1869 253308088b7e169231ab3d8f4408b216 280 Gene3D G3DSA:1.10.3470.10 38 268 1.3E-5 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MCR_1869 253308088b7e169231ab3d8f4408b216 280 SUPERFAMILY SSF81345 6 261 1.57E-35 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MCR_0852 de1272aeb17ada5c2a84c3635dfd7428 363 SUPERFAMILY SSF47648 24 89 1.96E-16 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MCR_0852 de1272aeb17ada5c2a84c3635dfd7428 363 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 27 357 2.1E-114 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MCR_0852 de1272aeb17ada5c2a84c3635dfd7428 363 Pfam PF00591 Glycosyl transferase family, a/b domain 93 348 2.0E-90 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MCR_0852 de1272aeb17ada5c2a84c3635dfd7428 363 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 24 358 35.623 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MCR_0852 de1272aeb17ada5c2a84c3635dfd7428 363 SUPERFAMILY SSF52418 94 360 4.58E-84 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MCR_0852 de1272aeb17ada5c2a84c3635dfd7428 363 Gene3D G3DSA:3.40.1030.10 91 363 2.4E-96 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MCR_0852 de1272aeb17ada5c2a84c3635dfd7428 363 Gene3D G3DSA:1.20.970.10 20 89 6.4E-20 T 14-10-2018 MCR_0852 de1272aeb17ada5c2a84c3635dfd7428 363 Pfam PF02885 Glycosyl transferase family, helical bundle domain 25 83 3.8E-15 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MCR_0897 d1685d622e807e200e404105881e8b8b 411 PIRSF PIRSF001434 18 411 3.2E-126 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MCR_0897 d1685d622e807e200e404105881e8b8b 411 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 22 408 3.6E-164 T 14-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 MCR_0897 d1685d622e807e200e404105881e8b8b 411 SUPERFAMILY SSF53383 39 410 2.79E-114 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0897 d1685d622e807e200e404105881e8b8b 411 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 213 227 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MCR_0897 d1685d622e807e200e404105881e8b8b 411 Gene3D G3DSA:3.90.1150.10 271 411 2.0E-46 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_0897 d1685d622e807e200e404105881e8b8b 411 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 23 409 51.429 T 14-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 MCR_0897 d1685d622e807e200e404105881e8b8b 411 Gene3D G3DSA:3.40.640.10 18 268 1.2E-85 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_0897 d1685d622e807e200e404105881e8b8b 411 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 22 408 5.5E-130 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MCR_0805 e84632bc97bd74079fb90f881e4f6d8d 416 SUPERFAMILY SSF55681 10 338 3.67E-44 T 14-10-2018 MCR_0805 e84632bc97bd74079fb90f881e4f6d8d 416 PIRSF PIRSF001549 8 381 1.5E-38 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MCR_0805 e84632bc97bd74079fb90f881e4f6d8d 416 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 22 392 22.713 T 14-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 MCR_0805 e84632bc97bd74079fb90f881e4f6d8d 416 Pfam PF13393 Histidyl-tRNA synthetase 15 335 1.6E-83 T 14-10-2018 MCR_0805 e84632bc97bd74079fb90f881e4f6d8d 416 Gene3D G3DSA:3.30.930.10 7 346 8.3E-57 T 14-10-2018 MCR_1899 c6d72df4f29be9413e3eac87042ee6c9 350 PIRSF PIRSF006769 246 349 4.6E-12 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 MCR_1899 c6d72df4f29be9413e3eac87042ee6c9 350 PIRSF PIRSF006769 6 261 4.0E-99 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 MCR_1899 c6d72df4f29be9413e3eac87042ee6c9 350 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 14 344 7.2E-103 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 MCR_1899 c6d72df4f29be9413e3eac87042ee6c9 350 Gene3D G3DSA:3.40.140.10 2 150 5.4E-46 T 14-10-2018 MCR_1899 c6d72df4f29be9413e3eac87042ee6c9 350 Gene3D G3DSA:3.40.430.10 151 260 3.6E-32 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MCR_1899 c6d72df4f29be9413e3eac87042ee6c9 350 Gene3D G3DSA:3.40.430.10 261 349 7.6E-16 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MCR_1899 c6d72df4f29be9413e3eac87042ee6c9 350 Pfam PF01872 RibD C-terminal domain 157 320 2.0E-38 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MCR_1899 c6d72df4f29be9413e3eac87042ee6c9 350 SUPERFAMILY SSF53927 10 155 5.02E-48 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MCR_1899 c6d72df4f29be9413e3eac87042ee6c9 350 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 9 109 3.6E-21 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MCR_1899 c6d72df4f29be9413e3eac87042ee6c9 350 SUPERFAMILY SSF53597 154 346 2.87E-45 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MCR_1899 c6d72df4f29be9413e3eac87042ee6c9 350 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 57 98 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MCR_0892 52a9b28a7e4c6fed34eb4839f40cc2ac 924 Gene3D G3DSA:3.40.50.920 712 892 9.4E-69 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MCR_0892 52a9b28a7e4c6fed34eb4839f40cc2ac 924 Gene3D G3DSA:3.40.50.970 478 711 3.5E-103 T 14-10-2018 MCR_0892 52a9b28a7e4c6fed34eb4839f40cc2ac 924 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 362 415 2.4E-4 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MCR_0892 52a9b28a7e4c6fed34eb4839f40cc2ac 924 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 111 303 1.6E-8 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MCR_0892 52a9b28a7e4c6fed34eb4839f40cc2ac 924 PIRSF PIRSF000156 5 893 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MCR_0892 52a9b28a7e4c6fed34eb4839f40cc2ac 924 SUPERFAMILY SSF52922 707 889 1.92E-53 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MCR_0892 52a9b28a7e4c6fed34eb4839f40cc2ac 924 SUPERFAMILY SSF52518 478 706 1.06E-93 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MCR_0892 52a9b28a7e4c6fed34eb4839f40cc2ac 924 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 13 891 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MCR_0892 52a9b28a7e4c6fed34eb4839f40cc2ac 924 Gene3D G3DSA:3.40.50.970 63 477 5.7E-131 T 14-10-2018 MCR_0892 52a9b28a7e4c6fed34eb4839f40cc2ac 924 SUPERFAMILY SSF52518 64 475 5.66E-137 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Gene3D G3DSA:2.150.10.10 5 115 3.9E-8 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Gene3D G3DSA:2.150.10.10 116 298 1.2E-31 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 SUPERFAMILY SSF101999 677 769 2.48E-7 T 14-10-2018 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Pfam PF03895 YadA-like membrane anchor domain 2030 2090 1.4E-16 T 14-10-2018 IPR005594 YadA-like, C-terminal MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Gene3D G3DSA:2.150.10.10 1833 1974 6.7E-29 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Gene3D G3DSA:1.20.5.170 1975 2016 2.4E-10 T 14-10-2018 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 SUPERFAMILY SSF101967 1799 1994 5.1E-31 T 14-10-2018 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Gene3D G3DSA:3.30.1300.30 2017 2090 3.2E-27 T 14-10-2018 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 SUPERFAMILY SSF101967 135 291 1.83E-26 T 14-10-2018 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1312 1348 9.5E-5 T 14-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 269 307 8.1E-9 T 14-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1969 2006 7.5E-13 T 14-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1639 1677 3.8E-4 T 14-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Gene3D G3DSA:2.150.10.10 1730 1832 5.5E-7 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 SUPERFAMILY SSF101999 940 1031 1.31E-7 T 14-10-2018 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 SUPERFAMILY SSF101967 1583 1661 7.72E-5 T 14-10-2018 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1804 1829 6.4E-8 T 14-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1833 1856 6.1E-7 T 14-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 SUPERFAMILY SSF101967 26 110 1.83E-8 T 14-10-2018 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 SUPERFAMILY SSF101999 1462 1512 2.48E-7 T 14-10-2018 MCR_0617 d72c03df2071e286e8a7809b03da4b0c 2090 SUPERFAMILY SSF54523 1983 2090 4.87E-23 T 14-10-2018 MCR_1651 81bc48330ecc18f3eb051f1b13ca3fb9 406 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 370 377 4.2E-7 T 14-10-2018 MCR_1651 81bc48330ecc18f3eb051f1b13ca3fb9 406 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.2E-7 T 14-10-2018 MCR_1651 81bc48330ecc18f3eb051f1b13ca3fb9 406 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 171 4.2E-7 T 14-10-2018 MCR_1651 81bc48330ecc18f3eb051f1b13ca3fb9 406 SUPERFAMILY SSF160996 197 348 1.83E-36 T 14-10-2018 MCR_1651 81bc48330ecc18f3eb051f1b13ca3fb9 406 Gene3D G3DSA:3.50.50.60 9 396 7.4E-120 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1651 81bc48330ecc18f3eb051f1b13ca3fb9 406 Pfam PF03486 HI0933-like protein 6 400 1.2E-135 T 14-10-2018 MCR_1651 81bc48330ecc18f3eb051f1b13ca3fb9 406 Gene3D G3DSA:2.40.30.10 195 347 7.4E-120 T 14-10-2018 MCR_1651 81bc48330ecc18f3eb051f1b13ca3fb9 406 SUPERFAMILY SSF51905 4 402 5.02E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1651 81bc48330ecc18f3eb051f1b13ca3fb9 406 Gene3D G3DSA:1.10.8.260 268 330 7.4E-120 T 14-10-2018 IPR023166 HI0933-like insert domain superfamily MCR_1651 81bc48330ecc18f3eb051f1b13ca3fb9 406 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 8 400 6.1E-119 T 14-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like MCR_1249 b77c486b70fa0ac60807d8a838f52849 243 SUPERFAMILY SSF47240 25 221 6.76E-72 T 14-10-2018 IPR009078 Ferritin-like superfamily MCR_1249 b77c486b70fa0ac60807d8a838f52849 243 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 25 74 6.8E-14 T 14-10-2018 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 MCR_1249 b77c486b70fa0ac60807d8a838f52849 243 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 75 218 1.4E-52 T 14-10-2018 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 MCR_1249 b77c486b70fa0ac60807d8a838f52849 243 Gene3D G3DSA:1.20.1260.10 21 226 4.3E-74 T 14-10-2018 IPR012347 Ferritin-like MCR_1249 b77c486b70fa0ac60807d8a838f52849 243 PIRSF PIRSF020736 16 223 4.0E-83 T 14-10-2018 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 MCR_1403 617780363479f166862300335c9450a7 260 SUPERFAMILY SSF110399 3 244 5.36E-88 T 14-10-2018 MCR_1403 617780363479f166862300335c9450a7 260 Hamap MF_00443 Thiazole synthase [thiG]. 4 259 41.802 T 14-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MCR_1403 617780363479f166862300335c9450a7 260 Pfam PF05690 Thiazole biosynthesis protein ThiG 7 253 2.7E-108 T 14-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MCR_1403 617780363479f166862300335c9450a7 260 Gene3D G3DSA:3.20.20.70 1 258 8.7E-118 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1441 b91840b8c4c95ac356bb4bd839806d78 212 Gene3D G3DSA:3.30.70.60 103 205 3.7E-15 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MCR_1441 b91840b8c4c95ac356bb4bd839806d78 212 Pfam PF04350 Pilus assembly protein, PilO 58 197 5.6E-23 T 14-10-2018 IPR007445 Pilus assembly protein, PilO MCR_0580 572d9ff39447524fdc3a163305805c4f 51 SUPERFAMILY SSF57829 1 49 7.32E-19 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MCR_0580 572d9ff39447524fdc3a163305805c4f 51 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 14-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0580 572d9ff39447524fdc3a163305805c4f 51 Gene3D G3DSA:2.20.28.120 1 51 4.5E-28 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0580 572d9ff39447524fdc3a163305805c4f 51 Pfam PF00471 Ribosomal protein L33 4 49 6.2E-18 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0580 572d9ff39447524fdc3a163305805c4f 51 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 51 6.6E-24 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0580 572d9ff39447524fdc3a163305805c4f 51 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 14.977 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0483 770311e6fef27df09cc13533494d8217 86 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MCR_0483 770311e6fef27df09cc13533494d8217 86 Gene3D G3DSA:3.30.70.20 2 86 1.3E-29 T 14-10-2018 MCR_0483 770311e6fef27df09cc13533494d8217 86 SUPERFAMILY SSF54862 6 72 4.39E-17 T 14-10-2018 MCR_0483 770311e6fef27df09cc13533494d8217 86 Pfam PF12838 4Fe-4S dicluster domain 9 60 5.1E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MCR_1387 c5d32e4b421b91e0a9ad75a5e59caac7 238 Hamap MF_00564 Ribonuclease PH [rph]. 11 237 44.095 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MCR_1387 c5d32e4b421b91e0a9ad75a5e59caac7 238 Pfam PF03725 3' exoribonuclease family, domain 2 158 222 8.7E-8 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_1387 c5d32e4b421b91e0a9ad75a5e59caac7 238 SUPERFAMILY SSF55666 154 236 6.28E-23 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_1387 c5d32e4b421b91e0a9ad75a5e59caac7 238 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 1.2E-23 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_1387 c5d32e4b421b91e0a9ad75a5e59caac7 238 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 8.3E-113 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MCR_1387 c5d32e4b421b91e0a9ad75a5e59caac7 238 Gene3D G3DSA:3.30.230.70 9 237 5.5E-62 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MCR_1387 c5d32e4b421b91e0a9ad75a5e59caac7 238 SUPERFAMILY SSF54211 1 181 9.11E-44 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1387 c5d32e4b421b91e0a9ad75a5e59caac7 238 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 14-10-2018 IPR018336 Ribonuclease PH, conserved site MCR_0361 d234731a76308aadbbd07e032f9a5ad8 864 SUPERFAMILY SSF52540 5 250 3.87E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0361 d234731a76308aadbbd07e032f9a5ad8 864 Gene3D G3DSA:3.40.50.300 57 251 1.7E-16 T 14-10-2018 MCR_0361 d234731a76308aadbbd07e032f9a5ad8 864 Pfam PF04851 Type III restriction enzyme, res subunit 6 234 2.9E-21 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MCR_0361 d234731a76308aadbbd07e032f9a5ad8 864 SUPERFAMILY SSF52540 80 520 5.91E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0361 d234731a76308aadbbd07e032f9a5ad8 864 Gene3D G3DSA:3.40.50.300 252 549 5.8E-8 T 14-10-2018 MCR_0361 d234731a76308aadbbd07e032f9a5ad8 864 SMART SM00487 55 257 0.0024 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MCR_0009 b77a8b15bb992a159537d6a477b2d5fe 164 Gene3D G3DSA:2.40.40.10 16 111 4.9E-31 T 14-10-2018 IPR036908 RlpA-like domain superfamily MCR_0009 b77a8b15bb992a159537d6a477b2d5fe 164 Pfam PF03330 Lytic transglycolase 19 105 1.7E-14 T 14-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MCR_0009 b77a8b15bb992a159537d6a477b2d5fe 164 SUPERFAMILY SSF50685 15 110 8.37E-14 T 14-10-2018 IPR036908 RlpA-like domain superfamily MCR_0009 b77a8b15bb992a159537d6a477b2d5fe 164 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 22 142 1.9E-27 T 14-10-2018 IPR012997 Rare lipoprotein A MCR_1319 0c2374abdccae8cdab2e44eb3377aee4 544 Gene3D G3DSA:3.40.50.300 1 286 1.2E-128 T 14-10-2018 MCR_1319 0c2374abdccae8cdab2e44eb3377aee4 544 Gene3D G3DSA:3.40.50.880 287 544 1.0E-98 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_1319 0c2374abdccae8cdab2e44eb3377aee4 544 Pfam PF06418 CTP synthase N-terminus 4 266 5.2E-122 T 14-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MCR_1319 0c2374abdccae8cdab2e44eb3377aee4 544 SUPERFAMILY SSF52317 290 542 5.18E-79 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_1319 0c2374abdccae8cdab2e44eb3377aee4 544 SUPERFAMILY SSF52540 3 270 2.9E-117 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1319 0c2374abdccae8cdab2e44eb3377aee4 544 Pfam PF00117 Glutamine amidotransferase class-I 302 537 1.3E-56 T 14-10-2018 IPR017926 Glutamine amidotransferase MCR_1319 0c2374abdccae8cdab2e44eb3377aee4 544 TIGRFAM TIGR00337 PyrG: CTP synthase 2 537 3.4E-240 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MCR_1319 0c2374abdccae8cdab2e44eb3377aee4 544 Hamap MF_01227 CTP synthase [pyrG]. 3 542 48.999 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MCR_1404 fd354bc0a5ab76b5f3ebd5e808891d42 107 Gene3D G3DSA:3.40.250.10 6 106 1.2E-15 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MCR_1404 fd354bc0a5ab76b5f3ebd5e808891d42 107 Pfam PF00581 Rhodanese-like domain 16 88 1.4E-8 T 14-10-2018 IPR001763 Rhodanese-like domain MCR_1404 fd354bc0a5ab76b5f3ebd5e808891d42 107 SMART SM00450 2 97 1.6E-7 T 14-10-2018 IPR001763 Rhodanese-like domain MCR_1404 fd354bc0a5ab76b5f3ebd5e808891d42 107 SUPERFAMILY SSF52821 14 99 1.44E-15 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 Gene3D G3DSA:1.10.287.130 271 385 1.4E-25 T 14-10-2018 MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 SMART SM00387 428 539 1.2E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 429 537 1.9E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 SUPERFAMILY SSF47384 302 384 1.29E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 536 3.7E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 491 3.7E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 516 3.7E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 477 3.7E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 SUPERFAMILY SSF158472 270 317 1.44E-6 T 14-10-2018 MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 SMART SM00388 319 384 1.6E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 Pfam PF00512 His Kinase A (phospho-acceptor) domain 319 384 7.9E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 Pfam PF00672 HAMP domain 270 314 2.0E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 Gene3D G3DSA:3.30.565.10 389 543 1.1E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 SUPERFAMILY SSF55874 373 537 4.85E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0386 14a304c961faa0c24d44139aeb143c6a 567 SMART SM00304 266 318 3.0E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MCR_1293 3107fb6fb7d22fa571465fc6dd5710a6 265 SUPERFAMILY SSF48317 28 257 6.54E-10 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MCR_1293 3107fb6fb7d22fa571465fc6dd5710a6 265 Pfam PF01569 PAP2 superfamily 132 258 4.8E-10 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MCR_1161 805afe125ee4a91931330b12b0640220 348 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 104 118 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site MCR_1161 805afe125ee4a91931330b12b0640220 348 Gene3D G3DSA:1.10.600.10 11 347 2.0E-96 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MCR_1161 805afe125ee4a91931330b12b0640220 348 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 225 237 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site MCR_1161 805afe125ee4a91931330b12b0640220 348 SUPERFAMILY SSF48576 25 346 3.78E-84 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MCR_1161 805afe125ee4a91931330b12b0640220 348 Pfam PF00348 Polyprenyl synthetase 53 296 3.6E-68 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 MCR_0145 97e964a66ed34749e0bfca54c1346245 302 ProSitePatterns PS01242 Zinc finger FPG-type signature. 266 290 - T 14-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 MCR_0145 97e964a66ed34749e0bfca54c1346245 302 SUPERFAMILY SSF46946 143 239 2.8E-26 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MCR_0145 97e964a66ed34749e0bfca54c1346245 302 Gene3D G3DSA:3.20.190.10 2 133 9.5E-31 T 14-10-2018 IPR035937 MutM-like, N-terminal MCR_0145 97e964a66ed34749e0bfca54c1346245 302 Gene3D G3DSA:1.10.8.50 146 291 2.0E-42 T 14-10-2018 MCR_0145 97e964a66ed34749e0bfca54c1346245 302 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 144 240 6.2E-24 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MCR_0145 97e964a66ed34749e0bfca54c1346245 302 SMART SM00898 2 123 7.0E-38 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MCR_0145 97e964a66ed34749e0bfca54c1346245 302 SMART SM01232 144 243 4.0E-41 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MCR_0145 97e964a66ed34749e0bfca54c1346245 302 Pfam PF06827 Zinc finger found in FPG and IleRS 263 291 1.7E-6 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MCR_0145 97e964a66ed34749e0bfca54c1346245 302 SUPERFAMILY SSF57716 239 291 2.14E-15 T 14-10-2018 MCR_0145 97e964a66ed34749e0bfca54c1346245 302 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 122 1.5E-25 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MCR_0145 97e964a66ed34749e0bfca54c1346245 302 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 290 5.6E-78 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MCR_0145 97e964a66ed34749e0bfca54c1346245 302 SUPERFAMILY SSF81624 2 153 6.93E-32 T 14-10-2018 IPR035937 MutM-like, N-terminal MCR_0145 97e964a66ed34749e0bfca54c1346245 302 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 291 38.867 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 PRINTS PR00143 Citrate synthase signature 354 368 4.8E-55 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 PRINTS PR00143 Citrate synthase signature 196 211 4.8E-55 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 PRINTS PR00143 Citrate synthase signature 271 291 4.8E-55 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 PRINTS PR00143 Citrate synthase signature 218 246 4.8E-55 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 PRINTS PR00143 Citrate synthase signature 141 154 4.8E-55 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 PRINTS PR00143 Citrate synthase signature 334 350 4.8E-55 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 PIRSF PIRSF001369 14 403 1.8E-168 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type MCR_0064 ae1251435038bab548a3efc0baa9e231 403 Pfam PF00285 Citrate synthase, C-terminal domain 22 385 3.0E-133 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 ProSitePatterns PS00480 Citrate synthase signature. 278 290 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 1 396 4.1E-213 T 14-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 SUPERFAMILY SSF48256 3 402 2.22E-159 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 Gene3D G3DSA:1.10.230.10 245 351 3.4E-143 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain MCR_0064 ae1251435038bab548a3efc0baa9e231 403 Gene3D G3DSA:1.10.580.10 33 385 3.4E-143 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MCR_0064 ae1251435038bab548a3efc0baa9e231 403 Gene3D G3DSA:2.20.28.60 1 26 2.5E-6 T 14-10-2018 MCR_1035 c0e6500f7766fe05ef7ce79e822cf27c 445 SUPERFAMILY SSF52540 175 425 1.59E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1035 c0e6500f7766fe05ef7ce79e822cf27c 445 SUPERFAMILY SSF48024 2 104 1.24E-24 T 14-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 MCR_1035 c0e6500f7766fe05ef7ce79e822cf27c 445 Pfam PF00772 DnaB-like helicase N terminal domain 2 96 2.1E-22 T 14-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MCR_1035 c0e6500f7766fe05ef7ce79e822cf27c 445 Gene3D G3DSA:1.10.860.10 1 152 9.3E-33 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MCR_1035 c0e6500f7766fe05ef7ce79e822cf27c 445 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 2 432 1.9E-140 T 14-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 MCR_1035 c0e6500f7766fe05ef7ce79e822cf27c 445 Gene3D G3DSA:3.40.50.300 153 433 7.5E-94 T 14-10-2018 MCR_1035 c0e6500f7766fe05ef7ce79e822cf27c 445 Pfam PF03796 DnaB-like helicase C terminal domain 175 431 4.7E-99 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MCR_1721 d6e972de09c12f8e97f9af2e71448c83 233 SUPERFAMILY SSF56784 11 223 3.47E-24 T 14-10-2018 IPR036412 HAD-like superfamily MCR_1721 d6e972de09c12f8e97f9af2e71448c83 233 Pfam PF12710 haloacid dehalogenase-like hydrolase 13 202 1.3E-28 T 14-10-2018 MCR_1721 d6e972de09c12f8e97f9af2e71448c83 233 Gene3D G3DSA:3.40.50.1000 12 227 8.2E-54 T 14-10-2018 IPR023214 HAD superfamily MCR_1721 d6e972de09c12f8e97f9af2e71448c83 233 Gene3D G3DSA:1.20.1440.100 24 97 8.2E-54 T 14-10-2018 MCR_1721 d6e972de09c12f8e97f9af2e71448c83 233 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 12 202 2.9E-18 T 14-10-2018 MCR_1270 e7d80bcf498e0ca703325a0802c170ad 239 Pfam PF01694 Rhomboid family 56 198 1.5E-23 T 14-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MCR_1270 e7d80bcf498e0ca703325a0802c170ad 239 SUPERFAMILY SSF144091 8 201 7.98E-28 T 14-10-2018 MCR_1270 e7d80bcf498e0ca703325a0802c170ad 239 Gene3D G3DSA:1.20.1540.10 4 209 1.7E-29 T 14-10-2018 IPR035952 Rhomboid-like superfamily MCR_0381 869e5f249e605b2fbc8902a0e9dcfade 290 Gene3D G3DSA:1.10.287.80 6 285 5.5E-104 T 14-10-2018 MCR_0381 869e5f249e605b2fbc8902a0e9dcfade 290 Pfam PF00231 ATP synthase 3 288 1.2E-93 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0381 869e5f249e605b2fbc8902a0e9dcfade 290 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 3.7E-36 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0381 869e5f249e605b2fbc8902a0e9dcfade 290 PRINTS PR00126 ATP synthase gamma subunit signature 236 255 3.7E-36 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0381 869e5f249e605b2fbc8902a0e9dcfade 290 PRINTS PR00126 ATP synthase gamma subunit signature 267 288 3.7E-36 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0381 869e5f249e605b2fbc8902a0e9dcfade 290 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 3.7E-36 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0381 869e5f249e605b2fbc8902a0e9dcfade 290 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 289 35.957 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0381 869e5f249e605b2fbc8902a0e9dcfade 290 Gene3D G3DSA:3.40.1380.10 61 208 5.5E-104 T 14-10-2018 MCR_0381 869e5f249e605b2fbc8902a0e9dcfade 290 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 275 288 - T 14-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0381 869e5f249e605b2fbc8902a0e9dcfade 290 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 289 1.0E-104 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0381 869e5f249e605b2fbc8902a0e9dcfade 290 SUPERFAMILY SSF52943 2 289 8.63E-93 T 14-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0913 139cccf0863c13e1fb3b12fe4272e562 155 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 1 146 22.848 T 14-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 MCR_0913 139cccf0863c13e1fb3b12fe4272e562 155 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 5 145 5.0E-41 T 14-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 MCR_0913 139cccf0863c13e1fb3b12fe4272e562 155 Pfam PF03968 OstA-like protein 18 124 1.7E-25 T 14-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal MCR_0913 139cccf0863c13e1fb3b12fe4272e562 155 Gene3D G3DSA:2.60.450.10 7 149 3.9E-39 T 14-10-2018 MCR_0150 fb7a331c9c6c5b7569b09ad0cc2bbfc2 497 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 311 488 2.8E-22 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MCR_0150 fb7a331c9c6c5b7569b09ad0cc2bbfc2 497 Gene3D G3DSA:2.40.50.140 18 113 8.9E-19 T 14-10-2018 MCR_0150 fb7a331c9c6c5b7569b09ad0cc2bbfc2 497 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 32 495 63.433 T 14-10-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 MCR_0150 fb7a331c9c6c5b7569b09ad0cc2bbfc2 497 Gene3D G3DSA:3.40.1350.30 161 322 1.4E-99 T 14-10-2018 MCR_0150 fb7a331c9c6c5b7569b09ad0cc2bbfc2 497 Gene3D G3DSA:3.40.50.150 114 489 1.4E-99 T 14-10-2018 MCR_0150 fb7a331c9c6c5b7569b09ad0cc2bbfc2 497 SUPERFAMILY SSF53335 102 494 3.17E-76 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0150 fb7a331c9c6c5b7569b09ad0cc2bbfc2 497 SUPERFAMILY SSF50249 30 92 3.03E-8 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0150 fb7a331c9c6c5b7569b09ad0cc2bbfc2 497 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 60 487 7.1E-88 T 14-10-2018 MCR_0150 fb7a331c9c6c5b7569b09ad0cc2bbfc2 497 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 426 456 - T 14-10-2018 IPR030390 RNA methyltransferase TrmA, active site MCR_1838 f4ab3b1a05e3585ed22ceb9a3110746b 279 Gene3D G3DSA:1.10.287.1080 3 130 1.3E-40 T 14-10-2018 MCR_1838 f4ab3b1a05e3585ed22ceb9a3110746b 279 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 27 105 2.3E-22 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MCR_1838 f4ab3b1a05e3585ed22ceb9a3110746b 279 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 173 244 1.1E-8 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MCR_1838 f4ab3b1a05e3585ed22ceb9a3110746b 279 SUPERFAMILY SSF101386 152 254 2.94E-23 T 14-10-2018 MCR_1838 f4ab3b1a05e3585ed22ceb9a3110746b 279 TIGRFAM TIGR00444 mazG: MazG family protein 14 275 8.0E-73 T 14-10-2018 IPR011551 NTP pyrophosphohydrolase MazG MCR_1838 f4ab3b1a05e3585ed22ceb9a3110746b 279 SUPERFAMILY SSF101386 6 107 1.64E-19 T 14-10-2018 MCR_1838 f4ab3b1a05e3585ed22ceb9a3110746b 279 Gene3D G3DSA:1.10.287.1080 141 279 4.7E-37 T 14-10-2018 MCR_0847 389dda4fd8072c8fcfcd7222071700ca 328 SUPERFAMILY SSF55174 25 118 1.62E-16 T 14-10-2018 MCR_0847 389dda4fd8072c8fcfcd7222071700ca 328 SUPERFAMILY SSF55120 86 255 3.74E-40 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0847 389dda4fd8072c8fcfcd7222071700ca 328 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 126 140 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MCR_0847 389dda4fd8072c8fcfcd7222071700ca 328 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 92 252 4.0E-50 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MCR_0847 389dda4fd8072c8fcfcd7222071700ca 328 Pfam PF01479 S4 domain 25 68 5.1E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0847 389dda4fd8072c8fcfcd7222071700ca 328 Pfam PF00849 RNA pseudouridylate synthase 88 220 1.7E-15 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0847 389dda4fd8072c8fcfcd7222071700ca 328 Gene3D G3DSA:3.30.70.580 90 247 7.2E-48 T 14-10-2018 MCR_0847 389dda4fd8072c8fcfcd7222071700ca 328 SMART SM00363 24 93 3.0E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0847 389dda4fd8072c8fcfcd7222071700ca 328 Gene3D G3DSA:3.10.290.10 19 79 2.9E-19 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MCR_0847 389dda4fd8072c8fcfcd7222071700ca 328 Gene3D G3DSA:3.30.70.1560 150 240 7.2E-48 T 14-10-2018 MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 SUPERFAMILY SSF52922 535 662 2.57E-37 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 ProSitePatterns PS00802 Transketolase signature 2. 470 486 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 SUPERFAMILY SSF52518 10 331 1.1E-116 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 Gene3D G3DSA:3.40.50.970 6 329 1.4E-129 T 14-10-2018 MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 Gene3D G3DSA:3.40.50.920 541 662 2.8E-36 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 8 337 8.1E-160 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 SMART SM00861 358 528 9.2E-65 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 SUPERFAMILY SSF52518 340 527 1.66E-66 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 661 7.0E-291 T 14-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 ProSitePatterns PS00801 Transketolase signature 1. 15 35 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 Pfam PF02780 Transketolase, C-terminal domain 554 654 4.3E-13 T 14-10-2018 IPR033248 Transketolase, C-terminal domain MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 Gene3D G3DSA:3.40.50.970 330 540 7.5E-80 T 14-10-2018 MCR_0537 ee94bf374bb3ab42cd66d8d810f1037a 662 Pfam PF02779 Transketolase, pyrimidine binding domain 357 526 5.2E-48 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MCR_0909 2fc2686b572b4640cfb809090ddcc2e5 325 Gene3D G3DSA:3.40.50.10490 8 199 1.6E-58 T 14-10-2018 MCR_0909 2fc2686b572b4640cfb809090ddcc2e5 325 SMART SM00116 213 261 9.9E-4 T 14-10-2018 IPR000644 CBS domain MCR_0909 2fc2686b572b4640cfb809090ddcc2e5 325 SMART SM00116 277 324 0.0061 T 14-10-2018 IPR000644 CBS domain MCR_0909 2fc2686b572b4640cfb809090ddcc2e5 325 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 49 314 1.5E-103 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MCR_0909 2fc2686b572b4640cfb809090ddcc2e5 325 PIRSF PIRSF004692 1 325 8.7E-129 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MCR_0909 2fc2686b572b4640cfb809090ddcc2e5 325 Pfam PF01380 SIS domain 45 176 1.3E-27 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MCR_0909 2fc2686b572b4640cfb809090ddcc2e5 325 SUPERFAMILY SSF53697 12 321 7.56E-61 T 14-10-2018 MCR_0909 2fc2686b572b4640cfb809090ddcc2e5 325 Pfam PF00571 CBS domain 205 261 4.8E-9 T 14-10-2018 IPR000644 CBS domain MCR_0909 2fc2686b572b4640cfb809090ddcc2e5 325 Pfam PF00571 CBS domain 273 322 5.6E-8 T 14-10-2018 IPR000644 CBS domain MCR_0909 2fc2686b572b4640cfb809090ddcc2e5 325 Gene3D G3DSA:3.10.580.10 200 322 2.0E-41 T 14-10-2018 MCR_1471 d27a83ae63402625eb17ee29cfbf959e 592 SUPERFAMILY SSF55486 200 410 4.76E-11 T 14-10-2018 MCR_1471 d27a83ae63402625eb17ee29cfbf959e 592 Pfam PF05299 M61 glycyl aminopeptidase 284 400 1.2E-41 T 14-10-2018 IPR007963 Peptidase M61, catalytic domain MCR_1471 d27a83ae63402625eb17ee29cfbf959e 592 Gene3D G3DSA:2.60.40.3650 2 184 8.3E-35 T 14-10-2018 MCR_1471 d27a83ae63402625eb17ee29cfbf959e 592 Gene3D G3DSA:1.10.390.60 195 465 9.6E-88 T 14-10-2018 MCR_1471 d27a83ae63402625eb17ee29cfbf959e 592 Pfam PF13180 PDZ domain 491 565 4.2E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MCR_1471 d27a83ae63402625eb17ee29cfbf959e 592 SUPERFAMILY SSF50156 483 565 2.8E-10 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 MCR_1471 d27a83ae63402625eb17ee29cfbf959e 592 SMART SM00228 488 558 0.0025 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MCR_1471 d27a83ae63402625eb17ee29cfbf959e 592 PIRSF PIRSF016493 1 583 6.3E-158 T 14-10-2018 IPR024191 Peptidase M61 MCR_1471 d27a83ae63402625eb17ee29cfbf959e 592 Gene3D G3DSA:2.30.42.10 488 587 6.1E-13 T 14-10-2018 MCR_0371 56f749585b7a02b6bb135c560dcae33a 258 Pfam PF00005 ABC transporter 29 157 4.3E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0371 56f749585b7a02b6bb135c560dcae33a 258 Gene3D G3DSA:3.40.50.300 2 249 1.5E-54 T 14-10-2018 MCR_0371 56f749585b7a02b6bb135c560dcae33a 258 SMART SM00382 37 206 2.5E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0371 56f749585b7a02b6bb135c560dcae33a 258 SUPERFAMILY SSF52540 8 222 2.24E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1202 1631710970150a4650c8eb2d07a96714 263 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 4 263 35.384 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MCR_1202 1631710970150a4650c8eb2d07a96714 263 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 174 263 1.5E-18 T 14-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MCR_1202 1631710970150a4650c8eb2d07a96714 263 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 6 263 1.0E-80 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MCR_1202 1631710970150a4650c8eb2d07a96714 263 SUPERFAMILY SSF56281 6 263 5.11E-57 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MCR_1202 1631710970150a4650c8eb2d07a96714 263 Pfam PF00753 Metallo-beta-lactamase superfamily 16 145 7.0E-18 T 14-10-2018 IPR001279 Metallo-beta-lactamase MCR_1202 1631710970150a4650c8eb2d07a96714 263 SMART SM00849 14 173 7.7E-29 T 14-10-2018 IPR001279 Metallo-beta-lactamase MCR_1202 1631710970150a4650c8eb2d07a96714 263 Gene3D G3DSA:3.60.15.10 1 263 8.3E-73 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MCR_1328 d241d681a041e2d083c9a799433b423b 322 Gene3D G3DSA:3.40.190.10 92 304 9.6E-57 T 14-10-2018 MCR_1328 d241d681a041e2d083c9a799433b423b 322 Pfam PF03466 LysR substrate binding domain 96 307 3.1E-16 T 14-10-2018 IPR005119 LysR, substrate-binding MCR_1328 d241d681a041e2d083c9a799433b423b 322 Gene3D G3DSA:3.40.190.10 170 280 9.6E-57 T 14-10-2018 MCR_1328 d241d681a041e2d083c9a799433b423b 322 SUPERFAMILY SSF46785 2 84 9.25E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_1328 d241d681a041e2d083c9a799433b423b 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1328 d241d681a041e2d083c9a799433b423b 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1328 d241d681a041e2d083c9a799433b423b 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1328 d241d681a041e2d083c9a799433b423b 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.5E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1328 d241d681a041e2d083c9a799433b423b 322 SUPERFAMILY SSF53850 90 307 5.97E-35 T 14-10-2018 MCR_1328 d241d681a041e2d083c9a799433b423b 322 Gene3D G3DSA:1.10.10.10 1 87 3.0E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_1578 350d3da6c980f652eae340a584e4c32b 137 SUPERFAMILY SSF54686 1 134 2.75E-55 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 MCR_1578 350d3da6c980f652eae340a584e4c32b 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1578 350d3da6c980f652eae340a584e4c32b 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1578 350d3da6c980f652eae340a584e4c32b 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.564 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1578 350d3da6c980f652eae340a584e4c32b 137 Gene3D G3DSA:3.90.1170.10 1 137 2.1E-56 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 MCR_1578 350d3da6c980f652eae340a584e4c32b 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 1.4E-58 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1578 350d3da6c980f652eae340a584e4c32b 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.4E-48 T 14-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MCR_1578 350d3da6c980f652eae340a584e4c32b 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 9.5E-38 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1578 350d3da6c980f652eae340a584e4c32b 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 9.5E-38 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1578 350d3da6c980f652eae340a584e4c32b 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 9.5E-38 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1578 350d3da6c980f652eae340a584e4c32b 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 9.5E-38 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0178 44ea5ed1e5d192759b3e566e05ae5278 348 TIGRFAM TIGR02314 ABC_MetN: D-methionine ABC transporter, ATP-binding protein 1 347 4.2E-159 T 14-10-2018 IPR012692 ABC transporter, methionine import, ATP-binding protein MetN, proteobacteria GO:0005524|GO:0009276|GO:0048473|GO:0048474 MCR_0178 44ea5ed1e5d192759b3e566e05ae5278 348 SUPERFAMILY SSF52540 2 244 4.18E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0178 44ea5ed1e5d192759b3e566e05ae5278 348 SMART SM00382 34 222 8.9E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0178 44ea5ed1e5d192759b3e566e05ae5278 348 SUPERFAMILY SSF55021 252 347 2.29E-18 T 14-10-2018 MCR_0178 44ea5ed1e5d192759b3e566e05ae5278 348 Gene3D G3DSA:3.30.70.260 237 347 2.4E-28 T 14-10-2018 MCR_0178 44ea5ed1e5d192759b3e566e05ae5278 348 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0178 44ea5ed1e5d192759b3e566e05ae5278 348 Gene3D G3DSA:3.40.50.300 7 236 1.7E-70 T 14-10-2018 MCR_0178 44ea5ed1e5d192759b3e566e05ae5278 348 SMART SM00930 269 344 1.8E-14 T 14-10-2018 IPR018449 NIL domain MCR_0178 44ea5ed1e5d192759b3e566e05ae5278 348 Pfam PF09383 NIL domain 272 342 4.7E-13 T 14-10-2018 IPR018449 NIL domain MCR_0178 44ea5ed1e5d192759b3e566e05ae5278 348 Pfam PF00005 ABC transporter 27 173 2.0E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0368 c71329687293fb0b2119cfd6e41586ed 139 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 19 127 8.8E-47 T 14-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 MCR_0368 c71329687293fb0b2119cfd6e41586ed 139 SUPERFAMILY SSF109635 3 94 6.67E-31 T 14-10-2018 IPR037187 DksA, N-terminal domain superfamily MCR_0368 c71329687293fb0b2119cfd6e41586ed 139 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 97 129 2.2E-11 T 14-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 MCR_0368 c71329687293fb0b2119cfd6e41586ed 139 Gene3D G3DSA:1.20.120.910 8 137 8.8E-34 T 14-10-2018 MCR_0368 c71329687293fb0b2119cfd6e41586ed 139 SUPERFAMILY SSF57716 98 135 4.99E-10 T 14-10-2018 MCR_0368 c71329687293fb0b2119cfd6e41586ed 139 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 101 125 - T 14-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site MCR_0368 c71329687293fb0b2119cfd6e41586ed 139 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 15 137 27.058 T 14-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 MCR_0790 6c0d83ced8638ecec317a94974142415 359 SMART SM00937 63 178 1.7E-61 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 MCR_0790 6c0d83ced8638ecec317a94974142415 359 Pfam PF00472 RF-1 domain 214 321 4.7E-41 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MCR_0790 6c0d83ced8638ecec317a94974142415 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 40.378 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MCR_0790 6c0d83ced8638ecec317a94974142415 359 Pfam PF03462 PCRF domain 13 203 1.8E-71 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 MCR_0790 6c0d83ced8638ecec317a94974142415 359 Gene3D G3DSA:3.30.160.20 210 297 6.4E-95 T 14-10-2018 MCR_0790 6c0d83ced8638ecec317a94974142415 359 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MCR_0790 6c0d83ced8638ecec317a94974142415 359 Gene3D G3DSA:1.20.58.410 6 100 4.4E-6 T 14-10-2018 MCR_0790 6c0d83ced8638ecec317a94974142415 359 SUPERFAMILY SSF75620 12 352 9.03E-135 T 14-10-2018 MCR_0790 6c0d83ced8638ecec317a94974142415 359 Gene3D G3DSA:3.30.70.1660 112 342 6.4E-95 T 14-10-2018 MCR_0790 6c0d83ced8638ecec317a94974142415 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 355 3.6E-160 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 SUPERFAMILY SSF52096 31 213 2.43E-73 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 22 212 2.1E-105 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 23 213 44.11 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 PRINTS PR00127 Clp protease catalytic subunit P signature 39 54 1.1E-52 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 PRINTS PR00127 Clp protease catalytic subunit P signature 131 150 1.1E-52 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 PRINTS PR00127 Clp protease catalytic subunit P signature 110 127 1.1E-52 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 PRINTS PR00127 Clp protease catalytic subunit P signature 188 207 1.1E-52 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 PRINTS PR00127 Clp protease catalytic subunit P signature 79 99 1.1E-52 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 132 145 - T 14-10-2018 IPR033135 ClpP, histidine active site MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 Gene3D G3DSA:3.90.226.10 12 215 1.7E-83 T 14-10-2018 MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 Pfam PF00574 Clp protease 33 212 4.8E-87 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MCR_0088 e5938b6a35a135684c8e777fbd4626d8 217 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 110 121 - T 14-10-2018 IPR018215 ClpP, Ser active site MCR_0478 a60f040d1657f744cbebc1737792585f 464 Gene3D G3DSA:1.10.45.10 423 463 1.0E-14 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MCR_0478 a60f040d1657f744cbebc1737792585f 464 Gene3D G3DSA:3.30.43.10 1 93 5.1E-22 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MCR_0478 a60f040d1657f744cbebc1737792585f 464 Pfam PF01565 FAD binding domain 43 180 5.7E-37 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MCR_0478 a60f040d1657f744cbebc1737792585f 464 Pfam PF02913 FAD linked oxidases, C-terminal domain 222 462 7.2E-57 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MCR_0478 a60f040d1657f744cbebc1737792585f 464 Gene3D G3DSA:3.30.465.10 96 216 9.4E-38 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MCR_0478 a60f040d1657f744cbebc1737792585f 464 SUPERFAMILY SSF55103 191 464 8.34E-59 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MCR_0478 a60f040d1657f744cbebc1737792585f 464 Gene3D G3DSA:3.30.70.2190 218 334 4.0E-23 T 14-10-2018 MCR_0478 a60f040d1657f744cbebc1737792585f 464 Gene3D G3DSA:3.30.70.2740 337 422 9.3E-27 T 14-10-2018 MCR_0478 a60f040d1657f744cbebc1737792585f 464 SUPERFAMILY SSF56176 6 218 2.43E-64 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MCR_1444 47d874e12a2047ddb3d7132daa8f6d0e 489 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 37 479 5.6E-142 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MCR_1444 47d874e12a2047ddb3d7132daa8f6d0e 489 SUPERFAMILY SSF102114 173 416 1.7E-62 T 14-10-2018 MCR_1444 47d874e12a2047ddb3d7132daa8f6d0e 489 Gene3D G3DSA:3.40.50.12160 36 170 3.9E-34 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily MCR_1444 47d874e12a2047ddb3d7132daa8f6d0e 489 Pfam PF00919 Uncharacterized protein family UPF0004 37 137 2.9E-28 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MCR_1444 47d874e12a2047ddb3d7132daa8f6d0e 489 SMART SM00729 191 411 1.4E-60 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MCR_1444 47d874e12a2047ddb3d7132daa8f6d0e 489 Pfam PF04055 Radical SAM superfamily 195 368 3.8E-27 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MCR_1444 47d874e12a2047ddb3d7132daa8f6d0e 489 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 195 215 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MCR_1444 47d874e12a2047ddb3d7132daa8f6d0e 489 Gene3D G3DSA:3.80.30.20 189 425 1.4E-80 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MCR_1444 47d874e12a2047ddb3d7132daa8f6d0e 489 Pfam PF01938 TRAM domain 423 476 1.5E-8 T 14-10-2018 IPR002792 TRAM domain MCR_1444 47d874e12a2047ddb3d7132daa8f6d0e 489 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 36 485 68.539 T 14-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 MCR_1444 47d874e12a2047ddb3d7132daa8f6d0e 489 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 37 484 2.3E-169 T 14-10-2018 MCR_0231 7ddee1d6cab054cb057c987917dd86ff 606 Gene3D G3DSA:1.20.140.10 287 459 3.8E-38 T 14-10-2018 MCR_0231 7ddee1d6cab054cb057c987917dd86ff 606 SUPERFAMILY SSF47203 286 472 5.8E-42 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MCR_0231 7ddee1d6cab054cb057c987917dd86ff 606 SUPERFAMILY SSF56645 36 279 6.41E-59 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MCR_0231 7ddee1d6cab054cb057c987917dd86ff 606 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 38 158 5.4E-17 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MCR_0231 7ddee1d6cab054cb057c987917dd86ff 606 Gene3D G3DSA:2.40.110.10 161 286 1.3E-27 T 14-10-2018 MCR_0231 7ddee1d6cab054cb057c987917dd86ff 606 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 282 454 7.6E-17 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MCR_0231 7ddee1d6cab054cb057c987917dd86ff 606 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 163 271 3.1E-17 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MCR_0231 7ddee1d6cab054cb057c987917dd86ff 606 Gene3D G3DSA:1.10.540.10 29 159 1.2E-19 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MCR_0231 7ddee1d6cab054cb057c987917dd86ff 606 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 485 598 1.8E-26 T 14-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain MCR_0231 7ddee1d6cab054cb057c987917dd86ff 606 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 28 1.1E-7 T 14-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria MCR_1015 1ea41fbe8883fec9dc0c53cf31a32313 289 Pfam PF03466 LysR substrate binding domain 89 287 5.1E-22 T 14-10-2018 IPR005119 LysR, substrate-binding MCR_1015 1ea41fbe8883fec9dc0c53cf31a32313 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 6.3E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1015 1ea41fbe8883fec9dc0c53cf31a32313 289 Gene3D G3DSA:3.40.190.290 93 287 1.7E-31 T 14-10-2018 MCR_1015 1ea41fbe8883fec9dc0c53cf31a32313 289 SUPERFAMILY SSF53850 89 288 1.76E-25 T 14-10-2018 MCR_1015 1ea41fbe8883fec9dc0c53cf31a32313 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 5.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1015 1ea41fbe8883fec9dc0c53cf31a32313 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 5.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1015 1ea41fbe8883fec9dc0c53cf31a32313 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 5.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_1015 1ea41fbe8883fec9dc0c53cf31a32313 289 Gene3D G3DSA:1.10.10.10 4 92 1.7E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_1015 1ea41fbe8883fec9dc0c53cf31a32313 289 SUPERFAMILY SSF46785 3 113 1.93E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_1870 88e708fd14a0162a76463c03ae5c57f4 280 SUPERFAMILY SSF81345 8 265 2.09E-41 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MCR_1870 88e708fd14a0162a76463c03ae5c57f4 280 Pfam PF00950 ABC 3 transport family 15 269 6.5E-86 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MCR_1870 88e708fd14a0162a76463c03ae5c57f4 280 Gene3D G3DSA:1.10.3470.10 40 272 1.1E-7 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MCR_1622 1200356dc46280023e4cdb3444bc9f8b 532 Gene3D G3DSA:3.20.20.60 411 531 5.4E-19 T 14-10-2018 MCR_1622 1200356dc46280023e4cdb3444bc9f8b 532 PIRSF PIRSF001362 416 531 6.1E-8 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MCR_1622 1200356dc46280023e4cdb3444bc9f8b 532 PIRSF PIRSF001362 288 419 6.2E-14 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MCR_1622 1200356dc46280023e4cdb3444bc9f8b 532 PIRSF PIRSF001362 2 292 3.4E-32 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MCR_1622 1200356dc46280023e4cdb3444bc9f8b 532 Pfam PF00463 Isocitrate lyase family 432 526 1.7E-11 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MCR_1622 1200356dc46280023e4cdb3444bc9f8b 532 Pfam PF00463 Isocitrate lyase family 87 269 9.0E-26 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MCR_1622 1200356dc46280023e4cdb3444bc9f8b 532 Pfam PF00463 Isocitrate lyase family 316 392 1.5E-11 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MCR_1622 1200356dc46280023e4cdb3444bc9f8b 532 SUPERFAMILY SSF51621 17 513 1.97E-126 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MCR_1010 d4ace89da94419f75d4aa05afecc05da 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 215 232 8.2E-10 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MCR_1010 d4ace89da94419f75d4aa05afecc05da 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 242 255 8.2E-10 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MCR_1010 d4ace89da94419f75d4aa05afecc05da 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 165 176 8.2E-10 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MCR_1010 d4ace89da94419f75d4aa05afecc05da 386 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 134 366 2.4E-46 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MCR_1010 d4ace89da94419f75d4aa05afecc05da 386 SUPERFAMILY SSF56601 128 379 4.87E-49 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MCR_1010 d4ace89da94419f75d4aa05afecc05da 386 Gene3D G3DSA:3.40.710.10 97 386 1.1E-56 T 14-10-2018 MCR_0640 a3c313a9dfdc1c0691c916fd2c1d21ba 353 TIGRFAM TIGR02584 cas_NE0113: CRISPR-associated protein, NE0113 family 4 116 2.7E-25 T 14-10-2018 IPR013413 CRISPR-associated protein, NE0113 MCR_0640 a3c313a9dfdc1c0691c916fd2c1d21ba 353 SUPERFAMILY SSF51197 192 350 1.04E-52 T 14-10-2018 MCR_0640 a3c313a9dfdc1c0691c916fd2c1d21ba 353 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 145 348 4.9E-24 T 14-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MCR_0640 a3c313a9dfdc1c0691c916fd2c1d21ba 353 Gene3D G3DSA:2.60.120.590 174 351 4.9E-54 T 14-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily MCR_0640 a3c313a9dfdc1c0691c916fd2c1d21ba 353 Pfam PF09623 CRISPR-associated protein NE0113 (Cas_NE0113) 12 116 3.0E-11 T 14-10-2018 IPR019092 CRISPR-assoc protein, NE0113/Csx13 MCR_0342 9f556c809e7512f108b139197c1fb2db 323 PIRSF PIRSF004491 3 323 6.1E-90 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MCR_0342 9f556c809e7512f108b139197c1fb2db 323 Pfam PF01687 Riboflavin kinase 178 313 3.1E-26 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 MCR_0342 9f556c809e7512f108b139197c1fb2db 323 SMART SM00904 177 320 5.2E-42 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 MCR_0342 9f556c809e7512f108b139197c1fb2db 323 SUPERFAMILY SSF82114 169 320 1.59E-33 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 MCR_0342 9f556c809e7512f108b139197c1fb2db 323 Pfam PF06574 FAD synthetase 17 160 4.9E-44 T 14-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MCR_0342 9f556c809e7512f108b139197c1fb2db 323 Gene3D G3DSA:2.40.30.30 182 321 7.2E-26 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 MCR_0342 9f556c809e7512f108b139197c1fb2db 323 Gene3D G3DSA:3.40.50.620 3 181 8.4E-54 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0342 9f556c809e7512f108b139197c1fb2db 323 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 313 2.7E-69 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MCR_0342 9f556c809e7512f108b139197c1fb2db 323 SUPERFAMILY SSF52374 17 172 2.74E-27 T 14-10-2018 MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 Pfam PF03023 MviN-like protein 33 467 6.4E-129 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 6 476 19.545 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 6 506 4.1E-128 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 PRINTS PR01806 Virulence factor MviN signature 418 435 1.1E-73 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 PRINTS PR01806 Virulence factor MviN signature 160 181 1.1E-73 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 PRINTS PR01806 Virulence factor MviN signature 55 71 1.1E-73 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 PRINTS PR01806 Virulence factor MviN signature 262 288 1.1E-73 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 PRINTS PR01806 Virulence factor MviN signature 360 379 1.1E-73 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 PRINTS PR01806 Virulence factor MviN signature 136 160 1.1E-73 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 PRINTS PR01806 Virulence factor MviN signature 36 55 1.1E-73 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 PIRSF PIRSF002869 1 515 5.2E-148 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MCR_0512 9b3545ced998564ec3e3366ae22e99a1 516 SUPERFAMILY SSF81665 76 495 6.15E-5 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MCR_0069 8334205cb8a34b0da2176d355cc6a200 236 Pfam PF13534 4Fe-4S dicluster domain 146 219 2.6E-8 T 14-10-2018 MCR_0069 8334205cb8a34b0da2176d355cc6a200 236 Gene3D G3DSA:1.10.1060.10 106 235 3.5E-55 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MCR_0069 8334205cb8a34b0da2176d355cc6a200 236 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 10 228 5.5E-83 T 14-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0069 8334205cb8a34b0da2176d355cc6a200 236 Gene3D G3DSA:3.10.20.30 2 105 8.6E-36 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MCR_0069 8334205cb8a34b0da2176d355cc6a200 236 SUPERFAMILY SSF54292 4 105 7.69E-28 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MCR_0069 8334205cb8a34b0da2176d355cc6a200 236 SUPERFAMILY SSF46548 106 233 1.74E-37 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MCR_0069 8334205cb8a34b0da2176d355cc6a200 236 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 110 7.2E-32 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0069 8334205cb8a34b0da2176d355cc6a200 236 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 147 158 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MCR_1772 05e5c969ba5437466029ce0e48f4770c 250 Pfam PF00121 Triosephosphate isomerase 6 243 1.5E-70 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1772 05e5c969ba5437466029ce0e48f4770c 250 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 245 47.438 T 14-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1772 05e5c969ba5437466029ce0e48f4770c 250 SUPERFAMILY SSF51351 4 245 8.51E-70 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1772 05e5c969ba5437466029ce0e48f4770c 250 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 14-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1772 05e5c969ba5437466029ce0e48f4770c 250 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 7 236 5.2E-45 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1772 05e5c969ba5437466029ce0e48f4770c 250 Gene3D G3DSA:3.20.20.70 1 248 2.2E-77 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 SUPERFAMILY SSF53901 6 262 4.51E-77 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 Gene3D G3DSA:3.40.47.10 9 271 1.8E-145 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 ProSitePatterns PS00099 Thiolases active site. 371 384 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 PIRSF PIRSF000429 3 390 7.0E-129 T 14-10-2018 IPR002155 Thiolase GO:0016747 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 91 109 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 Gene3D G3DSA:3.40.47.10 138 383 1.8E-145 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 ProSitePatterns PS00737 Thiolases signature 2. 336 352 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 388 1.2E-132 T 14-10-2018 IPR002155 Thiolase GO:0016747 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 Pfam PF02803 Thiolase, C-terminal domain 265 389 5.0E-46 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 TIGRFAM TIGR02445 fadA: acetyl-CoA C-acyltransferase FadA 8 390 1.8E-197 T 14-10-2018 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 SUPERFAMILY SSF53901 266 389 6.58E-42 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 Pfam PF00108 Thiolase, N-terminal domain 9 257 2.8E-80 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MCR_0092 3dd6a58b85f5d49202ebf1081e7f4b11 390 Hamap MF_01620 3-ketoacyl-CoA thiolase [fadA]. 6 390 60.199 T 14-10-2018 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 MCR_1700 e1d97297d42f08cc9bb75de5661c48e5 269 Pfam PF02565 Recombination protein O C terminal 98 208 5.5E-5 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MCR_1700 e1d97297d42f08cc9bb75de5661c48e5 269 Gene3D G3DSA:1.20.1440.120 91 268 8.1E-35 T 14-10-2018 MCR_0496 f42a57e3c81cc1a21adbb52a8d9e75bc 389 Gene3D G3DSA:3.40.50.1820 32 375 3.9E-138 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0496 f42a57e3c81cc1a21adbb52a8d9e75bc 389 Gene3D G3DSA:1.10.1740.110 193 298 3.9E-138 T 14-10-2018 MCR_0496 f42a57e3c81cc1a21adbb52a8d9e75bc 389 PIRSF PIRSF000443 2 389 1.0E-130 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MCR_0496 f42a57e3c81cc1a21adbb52a8d9e75bc 389 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 7 387 29.172 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MCR_0496 f42a57e3c81cc1a21adbb52a8d9e75bc 389 Pfam PF00561 alpha/beta hydrolase fold 57 373 1.8E-36 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MCR_0496 f42a57e3c81cc1a21adbb52a8d9e75bc 389 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 27 386 2.0E-137 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MCR_0496 f42a57e3c81cc1a21adbb52a8d9e75bc 389 SUPERFAMILY SSF53474 19 387 4.59E-102 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_1088 d1f645ceb6f0acd51c2ad2ab88287375 433 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 26 428 1.6E-83 T 14-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MCR_1088 d1f645ceb6f0acd51c2ad2ab88287375 433 Gene3D G3DSA:3.30.9.50 103 310 4.9E-81 T 14-10-2018 MCR_1088 d1f645ceb6f0acd51c2ad2ab88287375 433 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 335 348 - T 14-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 MCR_1088 d1f645ceb6f0acd51c2ad2ab88287375 433 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 336 5.5E-20 T 14-10-2018 MCR_1088 d1f645ceb6f0acd51c2ad2ab88287375 433 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 187 202 5.5E-20 T 14-10-2018 MCR_1088 d1f645ceb6f0acd51c2ad2ab88287375 433 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 26 48 5.5E-20 T 14-10-2018 MCR_1088 d1f645ceb6f0acd51c2ad2ab88287375 433 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 5.5E-20 T 14-10-2018 MCR_1088 d1f645ceb6f0acd51c2ad2ab88287375 433 Gene3D G3DSA:3.50.50.60 26 376 4.9E-81 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1088 d1f645ceb6f0acd51c2ad2ab88287375 433 Pfam PF01494 FAD binding domain 25 354 2.8E-29 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 MCR_1088 d1f645ceb6f0acd51c2ad2ab88287375 433 SUPERFAMILY SSF51905 24 399 2.22E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Gene3D G3DSA:1.20.5.170 275 319 3.2E-16 T 14-10-2018 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 269 312 1.0E-11 T 14-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Pfam PF05658 Head domain of trimeric autotransporter adhesin 171 196 3.4E-6 T 14-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Gene3D G3DSA:2.150.10.10 2 115 5.0E-23 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Gene3D G3DSA:3.30.1300.30 688 816 3.5E-22 T 14-10-2018 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 SUPERFAMILY SSF54523 720 816 1.37E-17 T 14-10-2018 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 PRINTS PR01804 Ubiquitous surface protein signature 357 375 3.2E-48 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 PRINTS PR01804 Ubiquitous surface protein signature 310 329 3.2E-48 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 PRINTS PR01804 Ubiquitous surface protein signature 612 634 3.2E-48 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 PRINTS PR01804 Ubiquitous surface protein signature 783 796 3.2E-48 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 PRINTS PR01804 Ubiquitous surface protein signature 595 609 3.2E-48 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 PRINTS PR01804 Ubiquitous surface protein signature 730 744 3.2E-48 T 14-10-2018 IPR008378 Ubiquitous surface protein MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Gene3D G3DSA:2.150.10.10 116 274 7.9E-56 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 SUPERFAMILY SSF69349 6 118 1.49E-10 T 14-10-2018 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Pfam PF06435 Repeat of unknown function (DUF1079) 526 556 6.9E-12 T 14-10-2018 IPR010494 Repeat of unknown function DUF1079 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Pfam PF06435 Repeat of unknown function (DUF1079) 421 451 6.9E-12 T 14-10-2018 IPR010494 Repeat of unknown function DUF1079 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Pfam PF06435 Repeat of unknown function (DUF1079) 386 416 7.2E-17 T 14-10-2018 IPR010494 Repeat of unknown function DUF1079 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Pfam PF06435 Repeat of unknown function (DUF1079) 456 486 9.0E-16 T 14-10-2018 IPR010494 Repeat of unknown function DUF1079 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Pfam PF06435 Repeat of unknown function (DUF1079) 491 521 9.0E-16 T 14-10-2018 IPR010494 Repeat of unknown function DUF1079 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Pfam PF06435 Repeat of unknown function (DUF1079) 604 633 9.1E-16 T 14-10-2018 IPR010494 Repeat of unknown function DUF1079 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Pfam PF06435 Repeat of unknown function (DUF1079) 561 591 6.9E-12 T 14-10-2018 IPR010494 Repeat of unknown function DUF1079 MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 Pfam PF03895 YadA-like membrane anchor domain 755 816 1.3E-14 T 14-10-2018 IPR005594 YadA-like, C-terminal MCR_0329 489fd758b96b5ef0b9968597fbcd6c07 816 SUPERFAMILY SSF101967 109 294 1.18E-28 T 14-10-2018 MCR_1887 20be75bdfe8d2f2300219abfd6cbba49 213 SUPERFAMILY SSF53335 26 206 3.23E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1887 20be75bdfe8d2f2300219abfd6cbba49 213 Pfam PF05175 Methyltransferase small domain 42 207 7.5E-29 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MCR_1887 20be75bdfe8d2f2300219abfd6cbba49 213 Gene3D G3DSA:3.40.50.150 27 212 6.2E-32 T 14-10-2018 MCR_0983 5e8200e9c456aa010b333cb1ea480cec 220 Gene3D G3DSA:3.20.20.70 2 219 4.5E-36 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0983 5e8200e9c456aa010b333cb1ea480cec 220 Pfam PF02581 Thiamine monophosphate synthase 12 196 2.2E-34 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MCR_0983 5e8200e9c456aa010b333cb1ea480cec 220 SUPERFAMILY SSF51391 8 201 5.23E-37 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 Pfam PF01926 50S ribosome-binding GTPase 223 345 4.5E-23 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 Pfam PF10396 GTP-binding protein TrmE N-terminus 10 123 1.8E-33 T 14-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 15 466 1.5E-103 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 Pfam PF12631 MnmE helical domain 126 463 4.7E-55 T 14-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 Gene3D G3DSA:1.20.120.430 125 466 2.1E-101 T 14-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 221 385 9.9E-20 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 9 466 31.941 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 SUPERFAMILY SSF116878 124 466 3.01E-47 T 14-10-2018 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 SUPERFAMILY SSF52540 75 385 4.07E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 Gene3D G3DSA:3.30.1360.120 1 124 5.8E-37 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 290 308 2.8E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 223 243 2.8E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1901 b0edf4390b5721107dacdce9b08e7170 466 Gene3D G3DSA:3.40.50.300 221 394 2.1E-101 T 14-10-2018 MCR_0503 39f48af853939a914b22f462b1906df0 335 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 182 318 2.9E-11 T 14-10-2018 IPR026337 HEXXH motif domain MCR_1359 dd57a9dca3601c55b8982aa57a8d68ec 129 SUPERFAMILY SSF101738 1 114 3.66E-39 T 14-10-2018 IPR036760 SspB-like superfamily MCR_1359 dd57a9dca3601c55b8982aa57a8d68ec 129 PIRSF PIRSF005276 1 126 7.0E-42 T 14-10-2018 IPR007481 Stringent starvation protein B MCR_1359 dd57a9dca3601c55b8982aa57a8d68ec 129 Pfam PF04386 Stringent starvation protein B 4 116 5.6E-25 T 14-10-2018 IPR007481 Stringent starvation protein B MCR_1359 dd57a9dca3601c55b8982aa57a8d68ec 129 Gene3D G3DSA:2.30.30.220 1 124 8.2E-44 T 14-10-2018 IPR036760 SspB-like superfamily MCR_1581 552e48be817fbfa9dff87bcb46c98c83 91 Gene3D G3DSA:3.30.860.10 1 91 1.5E-39 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1581 552e48be817fbfa9dff87bcb46c98c83 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.9E-23 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1581 552e48be817fbfa9dff87bcb46c98c83 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.9E-23 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1581 552e48be817fbfa9dff87bcb46c98c83 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.9E-23 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1581 552e48be817fbfa9dff87bcb46c98c83 91 Pfam PF00203 Ribosomal protein S19 3 83 7.9E-35 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1581 552e48be817fbfa9dff87bcb46c98c83 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 6.1E-44 T 14-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 MCR_1581 552e48be817fbfa9dff87bcb46c98c83 91 SUPERFAMILY SSF54570 3 84 4.58E-34 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1581 552e48be817fbfa9dff87bcb46c98c83 91 PIRSF PIRSF002144 1 91 2.5E-32 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1581 552e48be817fbfa9dff87bcb46c98c83 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.057 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1581 552e48be817fbfa9dff87bcb46c98c83 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 14-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0444 70bd9341ee194d6d3c57da7144151fc3 372 Pfam PF00107 Zinc-binding dehydrogenase 200 323 3.3E-26 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MCR_0444 70bd9341ee194d6d3c57da7144151fc3 372 SUPERFAMILY SSF50129 3 191 1.43E-73 T 14-10-2018 IPR011032 GroES-like superfamily MCR_0444 70bd9341ee194d6d3c57da7144151fc3 372 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MCR_0444 70bd9341ee194d6d3c57da7144151fc3 372 Gene3D G3DSA:3.40.50.720 177 315 7.2E-153 T 14-10-2018 MCR_0444 70bd9341ee194d6d3c57da7144151fc3 372 SUPERFAMILY SSF51735 163 336 1.97E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0444 70bd9341ee194d6d3c57da7144151fc3 372 Gene3D G3DSA:3.90.180.10 9 367 7.2E-153 T 14-10-2018 MCR_0444 70bd9341ee194d6d3c57da7144151fc3 372 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 5 372 6.1E-220 T 14-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 MCR_0444 70bd9341ee194d6d3c57da7144151fc3 372 SMART SM00829 13 370 8.0E-5 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MCR_0444 70bd9341ee194d6d3c57da7144151fc3 372 SUPERFAMILY SSF50129 321 372 6.12E-12 T 14-10-2018 IPR011032 GroES-like superfamily MCR_0444 70bd9341ee194d6d3c57da7144151fc3 372 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 157 4.1E-26 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MCR_0737 44d3526cb54eff1ca0efa2f1bc48fe74 166 SUPERFAMILY SSF100950 3 123 5.92E-40 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MCR_0737 44d3526cb54eff1ca0efa2f1bc48fe74 166 SMART SM00882 6 165 2.6E-21 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MCR_0737 44d3526cb54eff1ca0efa2f1bc48fe74 166 Gene3D G3DSA:3.40.1080.10 2 156 5.0E-49 T 14-10-2018 MCR_0737 44d3526cb54eff1ca0efa2f1bc48fe74 166 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 19 34 - T 14-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 MCR_0737 44d3526cb54eff1ca0efa2f1bc48fe74 166 Pfam PF01144 Coenzyme A transferase 7 124 6.7E-42 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MCR_0409 04b8fd923df3cc84a8358803a8086f16 351 SUPERFAMILY SSF51735 101 257 4.64E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0409 04b8fd923df3cc84a8358803a8086f16 351 Gene3D G3DSA:3.30.1370.170 300 350 3.7E-5 T 14-10-2018 IPR038251 PdxB, dimerisation domain superfamily KEGG: 00750+1.1.1.290 MCR_0409 04b8fd923df3cc84a8358803a8086f16 351 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 123 150 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MCR_0409 04b8fd923df3cc84a8358803a8086f16 351 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 256 5.9E-33 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MCR_0409 04b8fd923df3cc84a8358803a8086f16 351 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 2 351 34.52 T 14-10-2018 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00750+1.1.1.290 MCR_0409 04b8fd923df3cc84a8358803a8086f16 351 Gene3D G3DSA:3.40.50.720 3 275 1.0E-96 T 14-10-2018 MCR_0409 04b8fd923df3cc84a8358803a8086f16 351 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 278 7.4E-14 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MCR_0409 04b8fd923df3cc84a8358803a8086f16 351 Gene3D G3DSA:3.40.50.720 99 257 1.0E-96 T 14-10-2018 MCR_0409 04b8fd923df3cc84a8358803a8086f16 351 SUPERFAMILY SSF52283 40 135 2.34E-14 T 14-10-2018 MCR_1657 36dc47ad0f552e600ef924ee5451272c 342 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 11 68 2.5E-13 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MCR_1657 36dc47ad0f552e600ef924ee5451272c 342 SUPERFAMILY SSF55811 182 340 1.62E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MCR_1657 36dc47ad0f552e600ef924ee5451272c 342 ProSitePatterns PS00893 Nudix box signature. 240 261 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MCR_1657 36dc47ad0f552e600ef924ee5451272c 342 Gene3D G3DSA:3.90.79.10 202 341 2.1E-34 T 14-10-2018 MCR_1657 36dc47ad0f552e600ef924ee5451272c 342 Pfam PF00293 NUDIX domain 217 334 2.1E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MCR_1657 36dc47ad0f552e600ef924ee5451272c 342 SUPERFAMILY SSF52374 11 155 3.49E-20 T 14-10-2018 MCR_1657 36dc47ad0f552e600ef924ee5451272c 342 Pfam PF01467 Cytidylyltransferase-like 11 66 2.5E-8 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MCR_1657 36dc47ad0f552e600ef924ee5451272c 342 Gene3D G3DSA:3.40.50.620 3 201 3.6E-60 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0380 655949da548306edb84346ea5196b397 514 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 2 513 50.119 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0380 655949da548306edb84346ea5196b397 514 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_0380 655949da548306edb84346ea5196b397 514 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 93 6.4E-14 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_0380 655949da548306edb84346ea5196b397 514 SUPERFAMILY SSF50615 11 95 1.35E-27 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_0380 655949da548306edb84346ea5196b397 514 Gene3D G3DSA:3.40.50.300 95 383 2.2E-131 T 14-10-2018 MCR_0380 655949da548306edb84346ea5196b397 514 SUPERFAMILY SSF52540 97 382 4.05E-94 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0380 655949da548306edb84346ea5196b397 514 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 376 3.9E-74 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_0380 655949da548306edb84346ea5196b397 514 Gene3D G3DSA:1.20.150.20 384 514 5.0E-51 T 14-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0380 655949da548306edb84346ea5196b397 514 Gene3D G3DSA:2.40.30.20 2 94 1.8E-30 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_0380 655949da548306edb84346ea5196b397 514 PIRSF PIRSF039088 2 514 5.2E-236 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0380 655949da548306edb84346ea5196b397 514 SUPERFAMILY SSF47917 384 511 4.45E-47 T 14-10-2018 MCR_0380 655949da548306edb84346ea5196b397 514 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 508 9.4E-47 T 14-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0380 655949da548306edb84346ea5196b397 514 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 4 511 3.3E-252 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0573 58791984d5c6739ab001206c7a6ec1e4 85 Gene3D G3DSA:2.40.50.100 21 85 2.4E-30 T 14-10-2018 MCR_0573 58791984d5c6739ab001206c7a6ec1e4 85 SUPERFAMILY SSF110324 2 82 9.77E-34 T 14-10-2018 MCR_0573 58791984d5c6739ab001206c7a6ec1e4 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.575 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0573 58791984d5c6739ab001206c7a6ec1e4 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.2E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0573 58791984d5c6739ab001206c7a6ec1e4 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.2E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0573 58791984d5c6739ab001206c7a6ec1e4 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.2E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0573 58791984d5c6739ab001206c7a6ec1e4 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 1.9E-38 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0573 58791984d5c6739ab001206c7a6ec1e4 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 14-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0573 58791984d5c6739ab001206c7a6ec1e4 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 69 2.0E-15 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0573 58791984d5c6739ab001206c7a6ec1e4 85 Pfam PF01016 Ribosomal L27 protein 2 82 1.2E-38 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1761 ab5fb8b44368d261caee37d23699358a 235 Pfam PF02462 Opacity family porin protein 82 235 1.6E-30 T 14-10-2018 IPR003394 Porin, opacity type GO:0015288|GO:0016020 MCR_1761 ab5fb8b44368d261caee37d23699358a 235 Gene3D G3DSA:2.40.160.20 41 235 2.4E-34 T 14-10-2018 MCR_1761 ab5fb8b44368d261caee37d23699358a 235 SUPERFAMILY SSF56925 43 235 7.59E-26 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MCR_0114 3bd38ad39c08cb3ba2bc904fbff0b24b 423 Pfam PF03616 Sodium/glutamate symporter 3 390 1.2E-135 T 14-10-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 MCR_0114 3bd38ad39c08cb3ba2bc904fbff0b24b 423 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 3 421 1.1E-151 T 14-10-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 MCR_0114 3bd38ad39c08cb3ba2bc904fbff0b24b 423 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 3 422 24.384 T 14-10-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 MCR_1219 49fbde7fd451fcd76e7a3cf61dfb8ca4 358 Gene3D G3DSA:3.20.20.210 1 358 1.4E-140 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MCR_1219 49fbde7fd451fcd76e7a3cf61dfb8ca4 358 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 9 355 7.1E-129 T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MCR_1219 49fbde7fd451fcd76e7a3cf61dfb8ca4 358 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 10 356 46.512 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MCR_1219 49fbde7fd451fcd76e7a3cf61dfb8ca4 358 SUPERFAMILY SSF51726 6 356 4.84E-108 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MCR_1219 49fbde7fd451fcd76e7a3cf61dfb8ca4 358 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 13 353 1.3E-126 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MCR_1219 49fbde7fd451fcd76e7a3cf61dfb8ca4 358 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 146 162 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MCR_1219 49fbde7fd451fcd76e7a3cf61dfb8ca4 358 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 26 35 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MCR_0327 c9edecd878955930ec56c08759455b4f 741 Pfam PF03971 Monomeric isocitrate dehydrogenase 5 737 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MCR_0327 c9edecd878955930ec56c08759455b4f 741 SUPERFAMILY SSF53659 3 740 0.0 T 14-10-2018 MCR_0327 c9edecd878955930ec56c08759455b4f 741 PIRSF PIRSF009407 1 741 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MCR_0327 c9edecd878955930ec56c08759455b4f 741 Gene3D G3DSA:3.40.718.10 406 648 1.1E-10 T 14-10-2018 MCR_0327 c9edecd878955930ec56c08759455b4f 741 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 2 740 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 SUPERFAMILY SSF51971 361 547 7.06E-42 T 14-10-2018 MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 Gene3D G3DSA:3.20.20.70 31 398 2.3E-124 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 35 357 4.2E-83 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 SUPERFAMILY SSF51395 32 389 1.88E-111 T 14-10-2018 MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 SUPERFAMILY SSF51905 502 670 7.93E-15 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 Gene3D G3DSA:3.40.50.720 404 710 2.8E-105 T 14-10-2018 MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 406 425 2.9E-15 T 14-10-2018 MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 488 506 2.9E-15 T 14-10-2018 MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 529 547 2.9E-15 T 14-10-2018 MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 404 677 2.0E-23 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 Gene3D G3DSA:3.50.50.60 500 669 2.8E-105 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 405 427 7.9E-6 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_1526 b5af46bb6fdc760ab017b77b806fb962 716 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 525 549 7.9E-6 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_1798 1a8b0db7c190078e2afa137140bf7010 612 Gene3D G3DSA:3.40.50.10490 450 597 1.2E-133 T 14-10-2018 MCR_1798 1a8b0db7c190078e2afa137140bf7010 612 Gene3D G3DSA:3.40.50.10490 252 611 1.2E-133 T 14-10-2018 MCR_1798 1a8b0db7c190078e2afa137140bf7010 612 Pfam PF13522 Glutamine amidotransferase domain 63 195 1.2E-18 T 14-10-2018 MCR_1798 1a8b0db7c190078e2afa137140bf7010 612 Gene3D G3DSA:3.60.20.10 2 244 5.4E-67 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MCR_1798 1a8b0db7c190078e2afa137140bf7010 612 SUPERFAMILY SSF53697 248 612 4.08E-103 T 14-10-2018 MCR_1798 1a8b0db7c190078e2afa137140bf7010 612 SUPERFAMILY SSF56235 2 224 4.63E-64 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MCR_1798 1a8b0db7c190078e2afa137140bf7010 612 Pfam PF01380 SIS domain 465 594 2.3E-27 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MCR_1798 1a8b0db7c190078e2afa137140bf7010 612 Pfam PF01380 SIS domain 292 415 5.0E-25 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MCR_1798 1a8b0db7c190078e2afa137140bf7010 612 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 612 37.482 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MCR_1798 1a8b0db7c190078e2afa137140bf7010 612 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 612 4.4E-245 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MCR_0370 8b59cc09d59d219fe78d179a257fdfa9 267 Gene3D G3DSA:1.10.3470.10 34 262 1.1E-5 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MCR_0370 8b59cc09d59d219fe78d179a257fdfa9 267 SUPERFAMILY SSF81345 5 255 3.14E-29 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MCR_0370 8b59cc09d59d219fe78d179a257fdfa9 267 Pfam PF00950 ABC 3 transport family 7 259 2.5E-49 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 Gene3D G3DSA:3.40.50.300 202 504 5.4E-57 T 14-10-2018 MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 SUPERFAMILY SSF52540 202 503 1.59E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 327 340 7.5E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 299 313 7.5E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 222 237 7.5E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 351 363 7.5E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 Pfam PF01078 Magnesium chelatase, subunit ChlI 203 404 1.9E-94 T 14-10-2018 IPR000523 Magnesium chelatase ChlI domain MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 412 504 3.0E-29 T 14-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 SUPERFAMILY SSF54211 12 172 3.45E-28 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 Gene3D G3DSA:3.30.230.10 32 173 3.8E-7 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 504 4.4E-191 T 14-10-2018 IPR004482 Mg chelatase-related protein MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 134 4.1E-42 T 14-10-2018 MCR_1527 b97a3471250ceac0e84f3d0bc15be756 504 SMART SM00382 223 402 7.2E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0684 2b4c676e02294e72c781814f1905907c 296 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 23 38 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MCR_0684 2b4c676e02294e72c781814f1905907c 296 Gene3D G3DSA:3.20.20.20 1 296 1.4E-102 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MCR_0684 2b4c676e02294e72c781814f1905907c 296 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 22 294 1.1E-86 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 MCR_0684 2b4c676e02294e72c781814f1905907c 296 Pfam PF00809 Pterin binding enzyme 24 279 1.6E-77 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MCR_0684 2b4c676e02294e72c781814f1905907c 296 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 57 70 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MCR_0684 2b4c676e02294e72c781814f1905907c 296 SUPERFAMILY SSF51717 13 296 1.7E-87 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MCR_0223 fc8b891c30e8fcb19757112b74288f62 459 PRINTS PR00095 Anthranilate synthase component I signature 311 324 6.0E-10 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MCR_0223 fc8b891c30e8fcb19757112b74288f62 459 PRINTS PR00095 Anthranilate synthase component I signature 297 310 6.0E-10 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MCR_0223 fc8b891c30e8fcb19757112b74288f62 459 PRINTS PR00095 Anthranilate synthase component I signature 390 404 6.0E-10 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MCR_0223 fc8b891c30e8fcb19757112b74288f62 459 Gene3D G3DSA:3.60.120.10 32 457 8.4E-110 T 14-10-2018 IPR005801 ADC synthase GO:0009058 MCR_0223 fc8b891c30e8fcb19757112b74288f62 459 Pfam PF00425 chorismate binding enzyme 193 447 1.9E-85 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MCR_0223 fc8b891c30e8fcb19757112b74288f62 459 SUPERFAMILY SSF56322 89 455 1.57E-100 T 14-10-2018 IPR005801 ADC synthase GO:0009058 MCR_1733 df739cb7a2cb02612aa26e5de4d9a76a 320 Gene3D G3DSA:1.10.3720.10 71 319 4.8E-30 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1733 df739cb7a2cb02612aa26e5de4d9a76a 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 306 2.0E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_1733 df739cb7a2cb02612aa26e5de4d9a76a 320 SUPERFAMILY SSF161098 37 304 3.55E-33 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1733 df739cb7a2cb02612aa26e5de4d9a76a 320 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 22 313 1.4E-94 T 14-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 MCR_1592 8d42891decc3f2a6383a005687462ff1 490 Gene3D G3DSA:1.10.10.410 429 489 9.7E-23 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MCR_1592 8d42891decc3f2a6383a005687462ff1 490 Gene3D G3DSA:1.10.150.380 308 427 9.4E-33 T 14-10-2018 MCR_1592 8d42891decc3f2a6383a005687462ff1 490 SUPERFAMILY SSF55931 12 307 7.19E-113 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MCR_1592 8d42891decc3f2a6383a005687462ff1 490 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 156 170 - T 14-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 MCR_1592 8d42891decc3f2a6383a005687462ff1 490 SMART SM00845 339 488 3.9E-77 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MCR_1592 8d42891decc3f2a6383a005687462ff1 490 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 11 488 2.4E-163 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MCR_1592 8d42891decc3f2a6383a005687462ff1 490 SUPERFAMILY SSF89095 308 415 2.75E-32 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 MCR_1592 8d42891decc3f2a6383a005687462ff1 490 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 10 489 37.258 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MCR_1592 8d42891decc3f2a6383a005687462ff1 490 Pfam PF02637 GatB domain 340 488 5.3E-52 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MCR_1592 8d42891decc3f2a6383a005687462ff1 490 Pfam PF02934 GatB/GatE catalytic domain 13 299 6.3E-106 T 14-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 MCR_0992 e1a5fe16d7b6b73a256ee3ceebaa4a9b 181 SUPERFAMILY SSF75217 9 166 6.8E-42 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MCR_0992 e1a5fe16d7b6b73a256ee3ceebaa4a9b 181 PIRSF PIRSF029256 8 168 1.7E-57 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MCR_0992 e1a5fe16d7b6b73a256ee3ceebaa4a9b 181 Pfam PF00588 SpoU rRNA Methylase family 9 157 6.5E-34 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MCR_0992 e1a5fe16d7b6b73a256ee3ceebaa4a9b 181 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 9 166 32.561 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MCR_0992 e1a5fe16d7b6b73a256ee3ceebaa4a9b 181 Gene3D G3DSA:3.40.1280.10 5 171 2.7E-57 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MCR_0323 dce24a3d34729598e3234c1cedb31aad 354 PIRSF PIRSF005963 5 343 5.1E-123 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MCR_0323 dce24a3d34729598e3234c1cedb31aad 354 Pfam PF04055 Radical SAM superfamily 98 259 1.1E-9 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MCR_0323 dce24a3d34729598e3234c1cedb31aad 354 Hamap MF_00206 Lipoyl synthase [lipA]. 1 330 136.619 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MCR_0323 dce24a3d34729598e3234c1cedb31aad 354 SUPERFAMILY SSF102114 59 323 5.62E-59 T 14-10-2018 MCR_0323 dce24a3d34729598e3234c1cedb31aad 354 Gene3D G3DSA:3.20.20.70 87 306 1.8E-19 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0323 dce24a3d34729598e3234c1cedb31aad 354 TIGRFAM TIGR00510 lipA: lipoyl synthase 41 320 1.1E-116 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MCR_0323 dce24a3d34729598e3234c1cedb31aad 354 SMART SM00729 91 297 8.2E-13 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MCR_1476 25169682906449cdfc0e666f2cd4004e 398 SUPERFAMILY SSF52096 48 379 1.59E-62 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MCR_1476 25169682906449cdfc0e666f2cd4004e 398 Pfam PF16113 Enoyl-CoA hydratase/isomerase 60 382 9.8E-104 T 14-10-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 MCR_1476 25169682906449cdfc0e666f2cd4004e 398 Gene3D G3DSA:3.90.226.10 45 398 2.8E-113 T 14-10-2018 MCR_1822 eff32f8c94f9cd1792d6958dda47ecb7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 5.3E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1822 eff32f8c94f9cd1792d6958dda47ecb7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 194 5.3E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1822 eff32f8c94f9cd1792d6958dda47ecb7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 5.3E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1822 eff32f8c94f9cd1792d6958dda47ecb7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 5.3E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1822 eff32f8c94f9cd1792d6958dda47ecb7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 165 5.3E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1822 eff32f8c94f9cd1792d6958dda47ecb7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 101 112 5.3E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1822 eff32f8c94f9cd1792d6958dda47ecb7 259 Pfam PF00106 short chain dehydrogenase 23 219 1.6E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1822 eff32f8c94f9cd1792d6958dda47ecb7 259 SUPERFAMILY SSF51735 17 253 4.2E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1822 eff32f8c94f9cd1792d6958dda47ecb7 259 Gene3D G3DSA:3.40.50.720 9 257 7.5E-65 T 14-10-2018 MCR_0547 e182829989ca701408093645a8305f17 337 SUPERFAMILY SSF51161 38 327 2.72E-68 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MCR_0547 e182829989ca701408093645a8305f17 337 Gene3D G3DSA:2.160.10.10 106 320 1.4E-55 T 14-10-2018 MCR_0547 e182829989ca701408093645a8305f17 337 Gene3D G3DSA:3.40.1390.10 8 105 7.2E-17 T 14-10-2018 MCR_0547 e182829989ca701408093645a8305f17 337 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 27 97 3.0E-16 T 14-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 MCR_0547 e182829989ca701408093645a8305f17 337 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 3 337 32.921 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 MCR_0547 e182829989ca701408093645a8305f17 337 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 119 147 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MCR_0547 e182829989ca701408093645a8305f17 337 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 24 336 4.2E-94 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 MCR_0547 e182829989ca701408093645a8305f17 337 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 113 141 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MCR_0547 e182829989ca701408093645a8305f17 337 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 153 186 2.2E-6 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_0547 e182829989ca701408093645a8305f17 337 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 150 2.0E-6 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_0547 e182829989ca701408093645a8305f17 337 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 269 302 8.5E-4 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_0547 e182829989ca701408093645a8305f17 337 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 233 268 5.7E-5 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_0029 89932580704e31cda5efedb713d596ba 335 TIGRFAM TIGR02566 cas_Csy3: CRISPR type I-F/YPEST-associated protein Csy3 6 332 1.6E-126 T 14-10-2018 IPR013399 CRISPR-associated protein Csy3 MCR_0029 89932580704e31cda5efedb713d596ba 335 Pfam PF09615 CRISPR-associated protein (Cas_Csy3) 6 329 5.6E-145 T 14-10-2018 IPR013399 CRISPR-associated protein Csy3 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 Gene3D G3DSA:3.50.50.60 211 329 8.7E-93 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 Gene3D G3DSA:3.50.50.60 66 388 8.7E-93 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 Gene3D G3DSA:3.30.390.30 404 521 8.5E-33 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PIRSF PIRSF000350 7 520 1.5E-76 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 SUPERFAMILY SSF51905 65 379 3.7E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 466 481 1.6E-53 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 67 89 1.6E-53 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 202 211 1.6E-53 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 488 508 1.6E-53 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 100 115 1.6E-53 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 422 1.6E-53 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 323 337 1.6E-53 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 366 373 1.6E-53 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 263 1.6E-53 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 256 2.1E-29 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 68 87 2.1E-29 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 199 217 2.1E-29 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 373 2.1E-29 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 322 338 2.1E-29 T 14-10-2018 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 SUPERFAMILY SSF55424 403 520 3.44E-32 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 405 513 1.2E-29 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MCR_1106 6c6ca0c0ce899c276ecca3fe63c99201 522 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 66 386 3.9E-61 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 Pfam PF13328 HD domain 97 250 1.4E-29 T 14-10-2018 IPR003607 HD/PDEase domain MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 Gene3D G3DSA:3.30.70.260 710 788 1.3E-13 T 14-10-2018 MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 Gene3D G3DSA:3.10.20.30 455 527 6.3E-27 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 SUPERFAMILY SSF81271 457 518 5.45E-17 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 Gene3D G3DSA:3.30.460.10 268 398 3.6E-50 T 14-10-2018 MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 SMART SM00954 310 419 1.0E-57 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 Pfam PF04607 Region found in RelA / SpoT proteins 310 418 2.0E-33 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 Pfam PF13291 ACT domain 712 785 3.5E-13 T 14-10-2018 IPR002912 ACT domain MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 Pfam PF02824 TGS domain 459 518 4.8E-17 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 SUPERFAMILY SSF109604 68 265 3.01E-41 T 14-10-2018 MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 113 783 3.1E-164 T 14-10-2018 IPR004811 RelA/SpoT family GO:0015969 MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 SUPERFAMILY SSF55021 710 785 3.31E-10 T 14-10-2018 MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 Gene3D G3DSA:1.10.3210.10 64 266 7.8E-39 T 14-10-2018 MCR_0146 38f5cb6bacce4cbd445ae7b54bcfcb2d 788 SUPERFAMILY SSF81301 267 436 7.36E-57 T 14-10-2018 MCR_0263 93b5ff2378840b0665f5c41687bc2911 361 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 9 344 45.639 T 14-10-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 MCR_0263 93b5ff2378840b0665f5c41687bc2911 361 Gene3D G3DSA:3.20.20.300 6 345 5.4E-104 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 MCR_0263 93b5ff2378840b0665f5c41687bc2911 361 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 23 297 1.3E-70 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MCR_0263 93b5ff2378840b0665f5c41687bc2911 361 SUPERFAMILY SSF51445 9 303 7.48E-75 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MCR_1857 8c3e0a01d973d7b47791c91617762538 601 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 1 599 42.252 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 SUPERFAMILY SSF56719 363 592 7.06E-74 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 528 591 4.0E-25 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 SUPERFAMILY SSF55874 2 176 2.6E-53 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_1857 8c3e0a01d973d7b47791c91617762538 601 SMART SM00387 1 144 2.1E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_1857 8c3e0a01d973d7b47791c91617762538 601 Pfam PF01751 Toprim domain 388 482 1.2E-12 T 14-10-2018 IPR006171 TOPRIM domain MCR_1857 8c3e0a01d973d7b47791c91617762538 601 SMART SM00433 5 595 1.5E-200 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3 141 4.5E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_1857 8c3e0a01d973d7b47791c91617762538 601 Gene3D G3DSA:3.40.50.670 364 594 9.7E-88 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR00418 DNA topoisomerase II family signature 389 403 8.3E-58 T 14-10-2018 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR00418 DNA topoisomerase II family signature 472 489 8.3E-58 T 14-10-2018 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR00418 DNA topoisomerase II family signature 492 504 8.3E-58 T 14-10-2018 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR00418 DNA topoisomerase II family signature 2 17 8.3E-58 T 14-10-2018 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR00418 DNA topoisomerase II family signature 533 549 8.3E-58 T 14-10-2018 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR00418 DNA topoisomerase II family signature 241 254 8.3E-58 T 14-10-2018 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR00418 DNA topoisomerase II family signature 37 50 8.3E-58 T 14-10-2018 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR00418 DNA topoisomerase II family signature 80 94 8.3E-58 T 14-10-2018 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR00418 DNA topoisomerase II family signature 454 470 8.3E-58 T 14-10-2018 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 145 162 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 106 120 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 286 301 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 337 362 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 313 336 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 478 494 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 269 285 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 444 456 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 512 534 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 555 569 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 163 184 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 PRINTS PR01098 Topoisomerase IV subunit B signature 423 444 9.2E-69 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 Pfam PF00204 DNA gyrase B 190 359 2.8E-41 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 SUPERFAMILY SSF54211 189 356 1.54E-42 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1857 8c3e0a01d973d7b47791c91617762538 601 Gene3D G3DSA:3.30.565.10 2 184 6.1E-58 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_1857 8c3e0a01d973d7b47791c91617762538 601 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 2 596 9.7E-259 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1857 8c3e0a01d973d7b47791c91617762538 601 Gene3D G3DSA:3.30.230.10 188 363 3.6E-51 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MCR_1698 470615884070d135828f6248211752e2 453 PRINTS PR01021 OMPA domain signature 332 354 1.8E-7 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MCR_1698 470615884070d135828f6248211752e2 453 PRINTS PR01021 OMPA domain signature 380 396 1.8E-7 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MCR_1698 470615884070d135828f6248211752e2 453 SUPERFAMILY SSF103088 318 436 5.1E-32 T 14-10-2018 IPR036737 OmpA-like domain superfamily MCR_1698 470615884070d135828f6248211752e2 453 Gene3D G3DSA:2.40.160.20 37 235 2.1E-14 T 14-10-2018 MCR_1698 470615884070d135828f6248211752e2 453 SUPERFAMILY SSF56925 75 237 7.59E-12 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MCR_1698 470615884070d135828f6248211752e2 453 SUPERFAMILY SSF103647 281 317 1.96E-8 T 14-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MCR_1698 470615884070d135828f6248211752e2 453 Pfam PF00691 OmpA family 331 430 3.0E-21 T 14-10-2018 IPR006665 OmpA-like domain MCR_1698 470615884070d135828f6248211752e2 453 Gene3D G3DSA:3.30.1330.60 316 440 6.5E-38 T 14-10-2018 IPR036737 OmpA-like domain superfamily MCR_1698 470615884070d135828f6248211752e2 453 Pfam PF13505 Outer membrane protein beta-barrel domain 7 219 2.0E-8 T 14-10-2018 IPR027385 Outer membrane protein beta-barrel MCR_0741 ddf0a93c677562f2092e515b495f9334 496 Gene3D G3DSA:3.40.250.10 400 492 1.1E-8 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MCR_0741 ddf0a93c677562f2092e515b495f9334 496 Pfam PF02926 THUMP domain 60 171 2.9E-23 T 14-10-2018 IPR004114 THUMP domain GO:0003723 MCR_0741 ddf0a93c677562f2092e515b495f9334 496 SUPERFAMILY SSF52402 185 383 7.72E-40 T 14-10-2018 MCR_0741 ddf0a93c677562f2092e515b495f9334 496 SUPERFAMILY SSF52821 406 488 1.65E-9 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MCR_0741 ddf0a93c677562f2092e515b495f9334 496 TIGRFAM TIGR04271 ThiI_C_thiazole: thiazole biosynthesis domain 398 489 4.1E-33 T 14-10-2018 IPR026340 Thiazole biosynthesis domain GO:0052837 KEGG: 00730+2.8.1.4 MCR_0741 ddf0a93c677562f2092e515b495f9334 496 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 15 380 9.7E-114 T 14-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 MCR_0741 ddf0a93c677562f2092e515b495f9334 496 SUPERFAMILY SSF143437 12 183 3.14E-44 T 14-10-2018 MCR_0741 ddf0a93c677562f2092e515b495f9334 496 SMART SM00981 85 175 7.4E-20 T 14-10-2018 IPR004114 THUMP domain GO:0003723 MCR_0741 ddf0a93c677562f2092e515b495f9334 496 Gene3D G3DSA:3.30.2130.30 4 184 5.1E-33 T 14-10-2018 MCR_0741 ddf0a93c677562f2092e515b495f9334 496 Gene3D G3DSA:3.40.50.620 185 393 1.3E-48 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0741 ddf0a93c677562f2092e515b495f9334 496 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 496 184.508 T 14-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 MCR_0741 ddf0a93c677562f2092e515b495f9334 496 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 186 379 5.7E-69 T 14-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 SUPERFAMILY SSF53187 178 501 9.42E-114 T 14-10-2018 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 354 361 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 SUPERFAMILY SSF52949 25 181 1.53E-13 T 14-10-2018 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 184 495 5.3E-118 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 11 503 33.576 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 Gene3D G3DSA:3.40.220.10 15 177 1.4E-12 T 14-10-2018 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 Gene3D G3DSA:3.40.630.10 179 503 3.1E-129 T 14-10-2018 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 PRINTS PR00481 Cytosol aminopeptidase signature 328 349 1.4E-54 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 PRINTS PR00481 Cytosol aminopeptidase signature 379 394 1.4E-54 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 PRINTS PR00481 Cytosol aminopeptidase signature 269 286 1.4E-54 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 PRINTS PR00481 Cytosol aminopeptidase signature 291 312 1.4E-54 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 PRINTS PR00481 Cytosol aminopeptidase signature 350 370 1.4E-54 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MCR_1817 0a2d91332f293982cc1e1049a58ec628 503 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 29 147 4.4E-7 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MCR_1154 400d73d5681ded80cd9240414679b68c 180 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 20 178 29.422 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MCR_1154 400d73d5681ded80cd9240414679b68c 180 SUPERFAMILY SSF50324 6 179 9.29E-53 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MCR_1154 400d73d5681ded80cd9240414679b68c 180 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 71 77 - T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MCR_1154 400d73d5681ded80cd9240414679b68c 180 Pfam PF00719 Inorganic pyrophosphatase 24 177 2.6E-46 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MCR_1154 400d73d5681ded80cd9240414679b68c 180 Gene3D G3DSA:3.90.80.10 1 180 8.9E-65 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MCR_1228 1bb965de6bac0da8657cca5fabd45adc 907 Gene3D G3DSA:2.40.160.50 571 906 1.4E-87 T 14-10-2018 MCR_1228 1bb965de6bac0da8657cca5fabd45adc 907 Gene3D G3DSA:3.10.20.310 259 346 4.9E-18 T 14-10-2018 MCR_1228 1bb965de6bac0da8657cca5fabd45adc 907 Pfam PF01103 Surface antigen 600 907 4.0E-29 T 14-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 MCR_1228 1bb965de6bac0da8657cca5fabd45adc 907 Gene3D G3DSA:3.10.20.310 347 438 1.5E-6 T 14-10-2018 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 Gene3D G3DSA:3.10.290.10 328 400 4.3E-10 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 SUPERFAMILY SSF55174 329 401 4.06E-13 T 14-10-2018 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 45 55 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 5 401 44.868 T 14-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 Gene3D G3DSA:1.10.240.10 221 327 3.5E-30 T 14-10-2018 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 49 71 3.0E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 164 179 3.0E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 214 226 3.0E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 181 203 3.0E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 Pfam PF00579 tRNA synthetases class I (W and Y) 33 317 1.1E-74 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 Pfam PF01479 S4 domain 345 387 7.7E-7 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 11 400 3.3E-113 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 SUPERFAMILY SSF52374 10 313 8.45E-96 T 14-10-2018 MCR_1873 18506ed8efb8d7ce3e4eae4499e6741d 406 Gene3D G3DSA:3.40.50.620 7 220 2.1E-78 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_1898 2d13a5b3009069fb4747a5773920a438 222 Gene3D G3DSA:2.40.30.20 1 89 2.6E-28 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_1898 2d13a5b3009069fb4747a5773920a438 222 SUPERFAMILY SSF63380 1 90 7.65E-27 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MCR_1898 2d13a5b3009069fb4747a5773920a438 222 SUPERFAMILY SSF63380 93 197 7.57E-27 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MCR_1898 2d13a5b3009069fb4747a5773920a438 222 Gene3D G3DSA:2.40.30.20 102 207 2.6E-27 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_1898 2d13a5b3009069fb4747a5773920a438 222 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 202 1.3E-61 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_1898 2d13a5b3009069fb4747a5773920a438 222 Pfam PF00677 Lumazine binding domain 3 87 3.7E-22 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_1898 2d13a5b3009069fb4747a5773920a438 222 Pfam PF00677 Lumazine binding domain 101 187 1.7E-19 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_1898 2d13a5b3009069fb4747a5773920a438 222 PIRSF PIRSF000498 1 215 3.3E-71 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_0385 388c08231102671e57a6b0df5c0642b5 237 SMART SM00862 156 232 5.4E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MCR_0385 388c08231102671e57a6b0df5c0642b5 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 232 3.5E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MCR_0385 388c08231102671e57a6b0df5c0642b5 237 SMART SM00448 9 119 9.4E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_0385 388c08231102671e57a6b0df5c0642b5 237 Gene3D G3DSA:1.10.10.10 131 237 1.7E-38 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0385 388c08231102671e57a6b0df5c0642b5 237 Pfam PF00072 Response regulator receiver domain 11 120 6.3E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_0385 388c08231102671e57a6b0df5c0642b5 237 SUPERFAMILY SSF46894 132 233 3.12E-28 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MCR_0385 388c08231102671e57a6b0df5c0642b5 237 SUPERFAMILY SSF52172 6 130 3.27E-40 T 14-10-2018 IPR011006 CheY-like superfamily MCR_0385 388c08231102671e57a6b0df5c0642b5 237 Gene3D G3DSA:3.40.50.2300 1 129 1.6E-36 T 14-10-2018 MCR_1692 6363fdcd2f66b22d937641681c05a4e3 265 Gene3D G3DSA:3.40.190.10 36 256 3.7E-68 T 14-10-2018 MCR_1692 6363fdcd2f66b22d937641681c05a4e3 265 SMART SM00062 35 258 6.0E-65 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MCR_1692 6363fdcd2f66b22d937641681c05a4e3 265 Gene3D G3DSA:3.40.190.10 121 213 3.7E-68 T 14-10-2018 MCR_1692 6363fdcd2f66b22d937641681c05a4e3 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 257 2.2E-63 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MCR_1692 6363fdcd2f66b22d937641681c05a4e3 265 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 58 71 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site MCR_1692 6363fdcd2f66b22d937641681c05a4e3 265 SMART SM00079 35 257 0.0033 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MCR_1692 6363fdcd2f66b22d937641681c05a4e3 265 SUPERFAMILY SSF53850 5 257 2.78E-67 T 14-10-2018 MCR_0049 f2f8521adf098ef2bec9c1be46dcebd7 315 Pfam PF01758 Sodium Bile acid symporter family 43 220 9.1E-48 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MCR_0049 f2f8521adf098ef2bec9c1be46dcebd7 315 Gene3D G3DSA:1.20.1530.20 1 308 2.0E-116 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily MCR_1356 32b7161f4bc65cf38bf4d53d5df141a0 408 SUPERFAMILY SSF81342 10 268 6.75E-89 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MCR_1356 32b7161f4bc65cf38bf4d53d5df141a0 408 SUPERFAMILY SSF81648 203 374 1.1E-45 T 14-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MCR_1356 32b7161f4bc65cf38bf4d53d5df141a0 408 Gene3D G3DSA:1.20.810.10 1 407 7.8E-150 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 MCR_1356 32b7161f4bc65cf38bf4d53d5df141a0 408 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 281 382 6.5E-43 T 14-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MCR_1356 32b7161f4bc65cf38bf4d53d5df141a0 408 PIRSF PIRSF038885 1 408 4.9E-153 T 14-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 MCR_1356 32b7161f4bc65cf38bf4d53d5df141a0 408 Pfam PF00033 Cytochrome b/b6/petB 27 214 7.6E-63 T 14-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 ProSitePatterns PS00760 Signal peptidases I lysine active site. 193 205 - T 14-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 308 327 7.0E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 191 203 7.0E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 127 143 7.0E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 114 346 4.0E-44 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 ProSitePatterns PS00501 Signal peptidases I serine active site. 136 143 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 Gene3D G3DSA:2.10.109.10 125 347 6.9E-59 T 14-10-2018 MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 Pfam PF00717 Peptidase S24-like 134 205 7.8E-18 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 Gene3D G3DSA:2.170.230.10 202 307 6.9E-59 T 14-10-2018 MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 ProSitePatterns PS00761 Signal peptidases I signature 3. 313 326 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 Pfam PF10502 Signal peptidase, peptidase S26 305 345 7.7E-5 T 14-10-2018 IPR019533 Peptidase S26 MCR_1703 f94a05b9eb0e0abd231472d6fc01403c 364 SUPERFAMILY SSF51306 125 349 1.46E-58 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 231 247 - T 14-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 303 1.3E-19 T 14-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 6 303 7.5E-112 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 SUPERFAMILY SSF54782 220 317 2.09E-25 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 SUPERFAMILY SSF53850 4 218 3.06E-83 T 14-10-2018 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 Gene3D G3DSA:3.30.160.40 221 314 1.5E-27 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 Gene3D G3DSA:3.40.190.10 7 210 5.8E-83 T 14-10-2018 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 5 305 38.419 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 6 212 2.5E-78 T 14-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 Gene3D G3DSA:3.40.190.10 103 202 5.8E-83 T 14-10-2018 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 PIRSF PIRSF001438 1 320 4.8E-121 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 1.8E-50 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 PRINTS PR00151 Porphobilinogen deaminase signature 230 247 1.8E-50 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 PRINTS PR00151 Porphobilinogen deaminase signature 124 141 1.8E-50 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 1.8E-50 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0018 37366c82866d7577283e42c54ca3bfb7 321 PRINTS PR00151 Porphobilinogen deaminase signature 143 160 1.8E-50 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0877 1d7d2eebe1bc554691c32836f94af1d0 275 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 148 159 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MCR_0877 1d7d2eebe1bc554691c32836f94af1d0 275 Gene3D G3DSA:3.20.20.20 30 97 1.3E-6 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MCR_0877 1d7d2eebe1bc554691c32836f94af1d0 275 Gene3D G3DSA:3.30.70.20 105 205 2.7E-14 T 14-10-2018 MCR_0877 1d7d2eebe1bc554691c32836f94af1d0 275 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 30 183 2.6E-50 T 14-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 MCR_0877 1d7d2eebe1bc554691c32836f94af1d0 275 Pfam PF14697 4Fe-4S dicluster domain 111 164 6.1E-15 T 14-10-2018 MCR_0877 1d7d2eebe1bc554691c32836f94af1d0 275 Pfam PF04060 Putative Fe-S cluster 39 72 6.6E-10 T 14-10-2018 IPR007202 4Fe-4S domain GO:0051536 MCR_0877 1d7d2eebe1bc554691c32836f94af1d0 275 SUPERFAMILY SSF54862 35 168 2.26E-23 T 14-10-2018 MCR_0877 1d7d2eebe1bc554691c32836f94af1d0 275 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 118 129 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MCR_1474 ea86bee2de1bba0c10daff28ce8b7a4f 551 Gene3D G3DSA:3.30.1330.60 383 537 9.7E-37 T 14-10-2018 IPR036737 OmpA-like domain superfamily MCR_1474 ea86bee2de1bba0c10daff28ce8b7a4f 551 PRINTS PR01021 OMPA domain signature 473 489 6.0E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MCR_1474 ea86bee2de1bba0c10daff28ce8b7a4f 551 PRINTS PR01021 OMPA domain signature 458 473 6.0E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MCR_1474 ea86bee2de1bba0c10daff28ce8b7a4f 551 PRINTS PR01021 OMPA domain signature 428 450 6.0E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MCR_1474 ea86bee2de1bba0c10daff28ce8b7a4f 551 SUPERFAMILY SSF103088 420 528 5.23E-33 T 14-10-2018 IPR036737 OmpA-like domain superfamily MCR_1474 ea86bee2de1bba0c10daff28ce8b7a4f 551 Pfam PF00691 OmpA family 427 522 1.6E-21 T 14-10-2018 IPR006665 OmpA-like domain MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 Pfam PF12848 ABC transporter 223 300 5.5E-6 T 14-10-2018 IPR032781 ABC-transporter extension domain MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 SUPERFAMILY SSF52540 3 232 1.38E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 Gene3D G3DSA:1.10.287.380 568 647 8.1E-19 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 Gene3D G3DSA:3.40.50.300 3 282 3.7E-61 T 14-10-2018 MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 Pfam PF16326 ABC transporter C-terminal domain 575 643 1.9E-16 T 14-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 Gene3D G3DSA:3.40.50.300 284 558 2.5E-58 T 14-10-2018 MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 Pfam PF00005 ABC transporter 339 474 3.1E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 Pfam PF00005 ABC transporter 19 183 3.7E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 ProSitePatterns PS00211 ABC transporters family signature. 446 460 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 SUPERFAMILY SSF52540 313 526 3.06E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 SMART SM00382 28 228 4.0E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0856 862894c98aff2ede0e4b058ff06fc87c 647 SMART SM00382 347 519 1.4E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0343 fec3363edde5896a6ec098c35cd5d515 276 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 48 276 27.975 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MCR_0343 fec3363edde5896a6ec098c35cd5d515 276 SUPERFAMILY SSF53335 97 275 8.36E-36 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0343 fec3363edde5896a6ec098c35cd5d515 276 Pfam PF02390 Putative methyltransferase 103 271 5.2E-51 T 14-10-2018 MCR_0343 fec3363edde5896a6ec098c35cd5d515 276 Gene3D G3DSA:3.40.50.150 85 276 1.6E-56 T 14-10-2018 MCR_0343 fec3363edde5896a6ec098c35cd5d515 276 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 99 273 4.8E-51 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MCR_0895 1bf612ba6e6d383c83728f451cc8c03a 1377 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 1 938 8.4E-121 T 14-10-2018 MCR_0895 1bf612ba6e6d383c83728f451cc8c03a 1377 Gene3D G3DSA:3.40.50.10930 5 355 6.1E-38 T 14-10-2018 MCR_0895 1bf612ba6e6d383c83728f451cc8c03a 1377 SUPERFAMILY SSF52980 1026 1367 2.63E-23 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MCR_0895 1bf612ba6e6d383c83728f451cc8c03a 1377 SUPERFAMILY SSF52540 462 897 2.55E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0895 1bf612ba6e6d383c83728f451cc8c03a 1377 SUPERFAMILY SSF52540 1 414 7.43E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0895 1bf612ba6e6d383c83728f451cc8c03a 1377 Gene3D G3DSA:1.10.10.160 94 243 6.1E-38 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily MCR_0895 1bf612ba6e6d383c83728f451cc8c03a 1377 Gene3D G3DSA:3.40.50.300 738 950 3.2E-39 T 14-10-2018 MCR_0895 1bf612ba6e6d383c83728f451cc8c03a 1377 Gene3D G3DSA:3.40.50.300 395 564 5.1E-25 T 14-10-2018 MCR_1701 3dec3d9515026da5bce503dabdf61d17 331 Pfam PF07650 KH domain 260 319 1.5E-16 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1701 3dec3d9515026da5bce503dabdf61d17 331 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 33 190 1.4E-28 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MCR_1701 3dec3d9515026da5bce503dabdf61d17 331 TIGRFAM TIGR00436 era: GTP-binding protein Era 32 314 1.5E-90 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1701 3dec3d9515026da5bce503dabdf61d17 331 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 34 54 8.4E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1701 3dec3d9515026da5bce503dabdf61d17 331 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 102 120 8.4E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1701 3dec3d9515026da5bce503dabdf61d17 331 SUPERFAMILY SSF54814 206 331 2.35E-35 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MCR_1701 3dec3d9515026da5bce503dabdf61d17 331 Hamap MF_00367 GTPase Era [era]. 29 331 35.993 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1701 3dec3d9515026da5bce503dabdf61d17 331 Pfam PF01926 50S ribosome-binding GTPase 34 148 6.6E-26 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1701 3dec3d9515026da5bce503dabdf61d17 331 Gene3D G3DSA:3.40.50.300 27 207 1.8E-50 T 14-10-2018 MCR_1701 3dec3d9515026da5bce503dabdf61d17 331 Gene3D G3DSA:3.30.300.20 209 331 2.9E-38 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MCR_1701 3dec3d9515026da5bce503dabdf61d17 331 SUPERFAMILY SSF52540 34 229 9.94E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 2.5E-50 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 2.5E-50 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 218 242 2.5E-50 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 187 208 2.5E-50 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 2.5E-50 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 2.5E-50 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 PRINTS PR01959 SuhB family inositol monophosphatase signature 108 127 1.5E-10 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 PRINTS PR01959 SuhB family inositol monophosphatase signature 208 220 1.5E-10 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 Pfam PF00459 Inositol monophosphatase family 2 262 9.0E-65 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 Gene3D G3DSA:3.30.540.10 1 144 2.1E-46 T 14-10-2018 MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 SUPERFAMILY SSF56655 1 271 4.45E-75 T 14-10-2018 MCR_1409 a1b0e96e33d641323204b0fd16a7a8e8 277 Gene3D G3DSA:3.40.190.80 145 273 5.7E-32 T 14-10-2018 MCR_1599 71c451e31c8ab7a01de1b8a38adaadaa 271 SUPERFAMILY SSF52540 2 270 3.14E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1599 71c451e31c8ab7a01de1b8a38adaadaa 271 Gene3D G3DSA:3.40.50.300 1 261 1.5E-66 T 14-10-2018 MCR_1599 71c451e31c8ab7a01de1b8a38adaadaa 271 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 228 3.5E-22 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MCR_1599 71c451e31c8ab7a01de1b8a38adaadaa 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 269 6.5E-107 T 14-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 MCR_1599 71c451e31c8ab7a01de1b8a38adaadaa 271 PIRSF PIRSF003092 1 271 7.6E-93 T 14-10-2018 IPR025501 ATP binding protein MinD MCR_1519 ec48d31f9bf3996c35c3d2ecd1efe72f 411 Gene3D G3DSA:3.30.160.390 10 93 8.7E-21 T 14-10-2018 IPR038488 Integrase, DNA-binding domain superfamily MCR_1519 ec48d31f9bf3996c35c3d2ecd1efe72f 411 Pfam PF13356 Arm DNA-binding domain 11 89 1.3E-12 T 14-10-2018 IPR025166 Integrase, DNA-binding domain MCR_1519 ec48d31f9bf3996c35c3d2ecd1efe72f 411 SUPERFAMILY SSF56349 102 395 4.41E-46 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MCR_1519 ec48d31f9bf3996c35c3d2ecd1efe72f 411 Pfam PF00589 Phage integrase family 209 385 2.2E-15 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MCR_1519 ec48d31f9bf3996c35c3d2ecd1efe72f 411 Gene3D G3DSA:1.10.443.10 221 396 1.1E-13 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MCR_1519 ec48d31f9bf3996c35c3d2ecd1efe72f 411 Gene3D G3DSA:1.10.150.130 99 220 2.7E-22 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal MCR_1714 92d8f2e5d64f2af5eed9e88a9a6a9bb6 294 SUPERFAMILY SSF103481 193 287 1.26E-9 T 14-10-2018 MCR_1714 92d8f2e5d64f2af5eed9e88a9a6a9bb6 294 Pfam PF00892 EamA-like transporter family 152 287 1.9E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MCR_1714 92d8f2e5d64f2af5eed9e88a9a6a9bb6 294 Pfam PF00892 EamA-like transporter family 11 140 2.4E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MCR_1714 92d8f2e5d64f2af5eed9e88a9a6a9bb6 294 SUPERFAMILY SSF103481 42 143 3.27E-11 T 14-10-2018 MCR_0320 1be00ff276e29146985b00bf68e0f9d0 273 Gene3D G3DSA:2.160.10.10 87 257 2.7E-54 T 14-10-2018 MCR_0320 1be00ff276e29146985b00bf68e0f9d0 273 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 272 57.153 T 14-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 MCR_0320 1be00ff276e29146985b00bf68e0f9d0 273 Gene3D G3DSA:1.10.166.10 1 70 1.4E-28 T 14-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 MCR_0320 1be00ff276e29146985b00bf68e0f9d0 273 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 175 209 3.5E-13 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_0320 1be00ff276e29146985b00bf68e0f9d0 273 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 4 69 2.8E-25 T 14-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 MCR_0320 1be00ff276e29146985b00bf68e0f9d0 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MCR_0320 1be00ff276e29146985b00bf68e0f9d0 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 133 166 0.0013 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_0320 1be00ff276e29146985b00bf68e0f9d0 273 SUPERFAMILY SSF51161 3 256 2.91E-71 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MCR_0320 1be00ff276e29146985b00bf68e0f9d0 273 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 4 272 2.7E-145 T 14-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 MCR_1240 071006eedf76fef9a41799110e722ef5 202 SUPERFAMILY SSF53335 15 195 8.79E-43 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1240 071006eedf76fef9a41799110e722ef5 202 Gene3D G3DSA:3.40.50.150 4 200 6.0E-51 T 14-10-2018 MCR_1240 071006eedf76fef9a41799110e722ef5 202 PIRSF PIRSF004553 14 200 4.5E-43 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MCR_1240 071006eedf76fef9a41799110e722ef5 202 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 9 193 2.4E-48 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MCR_1240 071006eedf76fef9a41799110e722ef5 202 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 131 137 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MCR_1240 071006eedf76fef9a41799110e722ef5 202 Pfam PF03602 Conserved hypothetical protein 95 15 195 9.9E-49 T 14-10-2018 MCR_0402 9954d983e188d8dd879077577a7d2ca8 258 Gene3D G3DSA:3.40.1280.10 107 257 1.8E-41 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MCR_0402 9954d983e188d8dd879077577a7d2ca8 258 SUPERFAMILY SSF75217 108 255 9.16E-35 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MCR_0402 9954d983e188d8dd879077577a7d2ca8 258 Gene3D G3DSA:3.30.1330.30 7 106 4.4E-12 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like MCR_0402 9954d983e188d8dd879077577a7d2ca8 258 Pfam PF00588 SpoU rRNA Methylase family 114 248 8.5E-28 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MCR_0402 9954d983e188d8dd879077577a7d2ca8 258 SUPERFAMILY SSF55315 1 102 8.59E-14 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like MCR_1856 d89ca1540b3c6141e4ee6738a2ef443f 208 PIRSF PIRSF000495 2 208 1.2E-65 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MCR_1856 d89ca1540b3c6141e4ee6738a2ef443f 208 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 206 32.36 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MCR_1856 d89ca1540b3c6141e4ee6738a2ef443f 208 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 205 8.5E-62 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MCR_1856 d89ca1540b3c6141e4ee6738a2ef443f 208 Pfam PF00117 Glutamine amidotransferase class-I 6 203 2.6E-16 T 14-10-2018 IPR017926 Glutamine amidotransferase MCR_1856 d89ca1540b3c6141e4ee6738a2ef443f 208 Gene3D G3DSA:3.40.50.880 1 207 1.2E-67 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_1856 d89ca1540b3c6141e4ee6738a2ef443f 208 SUPERFAMILY SSF52317 2 206 2.97E-50 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_1326 88d372dd3e92dd757a932ec6479dc357 483 Pfam PF13746 4Fe-4S dicluster domain 222 325 1.2E-43 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MCR_1326 88d372dd3e92dd757a932ec6479dc357 483 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 41 473 6.2E-144 T 14-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 MCR_1326 88d372dd3e92dd757a932ec6479dc357 483 Gene3D G3DSA:3.30.70.20 216 291 1.5E-5 T 14-10-2018 MCR_1326 88d372dd3e92dd757a932ec6479dc357 483 Gene3D G3DSA:2.60.40.10 356 475 1.5E-26 T 14-10-2018 IPR013783 Immunoglobulin-like fold MCR_1326 88d372dd3e92dd757a932ec6479dc357 483 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 273 284 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MCR_1326 88d372dd3e92dd757a932ec6479dc357 483 Pfam PF12801 4Fe-4S binding domain 95 136 8.1E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MCR_1326 88d372dd3e92dd757a932ec6479dc357 483 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 358 474 8.7E-24 T 14-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain MCR_1326 88d372dd3e92dd757a932ec6479dc357 483 SUPERFAMILY SSF54862 105 349 2.99E-27 T 14-10-2018 MCR_0160 c5397474db2ba79f728a8a6d6f51a217 440 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 10 418 3.2E-178 T 14-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MCR_0160 c5397474db2ba79f728a8a6d6f51a217 440 Gene3D G3DSA:3.90.1150.10 8 412 2.1E-163 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_0160 c5397474db2ba79f728a8a6d6f51a217 440 Gene3D G3DSA:3.40.640.10 58 328 2.1E-163 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_0160 c5397474db2ba79f728a8a6d6f51a217 440 SUPERFAMILY SSF53383 4 417 7.43E-126 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0160 c5397474db2ba79f728a8a6d6f51a217 440 Pfam PF00202 Aminotransferase class-III 24 418 1.1E-125 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MCR_0160 c5397474db2ba79f728a8a6d6f51a217 440 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MCR_1357 b41575c1797b77c0366ae5884a7bd9c8 241 SUPERFAMILY SSF46626 51 205 5.32E-44 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1357 b41575c1797b77c0366ae5884a7bd9c8 241 Pfam PF02167 Cytochrome C1 family 58 240 3.4E-19 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 MCR_1357 b41575c1797b77c0366ae5884a7bd9c8 241 Gene3D G3DSA:1.10.760.10 50 206 6.8E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_0042 fd359a9b8da0edd3718e65239d1710d0 390 SUPERFAMILY SSF56645 49 240 1.7E-21 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MCR_0042 fd359a9b8da0edd3718e65239d1710d0 390 Gene3D G3DSA:1.10.540.10 30 130 1.1E-11 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MCR_0042 fd359a9b8da0edd3718e65239d1710d0 390 Gene3D G3DSA:2.40.110.10 131 242 1.1E-11 T 14-10-2018 MCR_0042 fd359a9b8da0edd3718e65239d1710d0 390 Gene3D G3DSA:1.20.140.10 243 369 1.1E-11 T 14-10-2018 MCR_0133 440414e34a5d600458d61d9cb4eefe66 177 Gene3D G3DSA:1.10.10.10 1 173 4.8E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0133 440414e34a5d600458d61d9cb4eefe66 177 SUPERFAMILY SSF46785 2 99 8.2E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0133 440414e34a5d600458d61d9cb4eefe66 177 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 111 2.0E-28 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type MCR_0133 440414e34a5d600458d61d9cb4eefe66 177 Pfam PF02082 Transcriptional regulator 1 83 8.4E-24 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 Pfam PF07687 Peptidase dimerisation domain 225 299 2.8E-7 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 PIRSF PIRSF016599 12 502 1.5E-172 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 PRINTS PR00934 X-His dipeptidase (M25) signature 149 166 2.8E-66 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 PRINTS PR00934 X-His dipeptidase (M25) signature 219 236 2.8E-66 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 PRINTS PR00934 X-His dipeptidase (M25) signature 266 285 2.8E-66 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 PRINTS PR00934 X-His dipeptidase (M25) signature 380 398 2.8E-66 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 PRINTS PR00934 X-His dipeptidase (M25) signature 173 191 2.8E-66 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 PRINTS PR00934 X-His dipeptidase (M25) signature 445 461 2.8E-66 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 PRINTS PR00934 X-His dipeptidase (M25) signature 91 110 2.8E-66 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 PRINTS PR00934 X-His dipeptidase (M25) signature 467 489 2.8E-66 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 SUPERFAMILY SSF53187 23 498 2.51E-50 T 14-10-2018 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 Pfam PF01546 Peptidase family M20/M25/M40 83 497 1.6E-15 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 Gene3D G3DSA:3.40.630.10 12 247 5.7E-52 T 14-10-2018 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 Gene3D G3DSA:3.40.630.10 386 500 1.9E-22 T 14-10-2018 MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 SUPERFAMILY SSF55031 219 287 7.67E-5 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MCR_0206 a7d993bac1b3729fb98a43bda5c03ed6 503 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 20 498 1.4E-158 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 Gene3D G3DSA:3.30.565.10 385 555 7.9E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0156 8d2a44aab349c148d8933c4670793f23 988 Pfam PF00072 Response regulator receiver domain 706 826 5.0E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 SUPERFAMILY SSF47226 809 962 2.49E-15 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 Pfam PF00512 His Kinase A (phospho-acceptor) domain 320 386 3.9E-20 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 Pfam PF01627 Hpt domain 886 967 2.7E-7 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 SUPERFAMILY SSF52172 703 831 1.99E-31 T 14-10-2018 IPR011006 CheY-like superfamily MCR_0156 8d2a44aab349c148d8933c4670793f23 988 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 433 549 1.3E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0156 8d2a44aab349c148d8933c4670793f23 988 SUPERFAMILY SSF47384 306 387 6.28E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 SMART SM00448 704 826 1.2E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 SMART SM00387 433 551 3.2E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0156 8d2a44aab349c148d8933c4670793f23 988 Gene3D G3DSA:3.40.50.2300 685 832 2.6E-33 T 14-10-2018 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 Gene3D G3DSA:1.10.287.130 283 384 6.7E-27 T 14-10-2018 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 SMART SM00388 320 386 9.3E-24 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 SUPERFAMILY SSF55874 375 549 3.93E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0156 8d2a44aab349c148d8933c4670793f23 988 Gene3D G3DSA:1.20.120.160 863 979 9.1E-21 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 524 2.7E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 548 2.7E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0156 8d2a44aab349c148d8933c4670793f23 988 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 485 2.7E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0021 15a3e5b34e2a928b473d7d10398e24d6 85 Pfam PF04400 (Na+)-NQR maturation NqrM 30 75 2.5E-16 T 14-10-2018 IPR007495 (Na+)-NQR maturation factor NqrM MCR_1677 91f451b334095370f1328ecf6b20c85d 94 Gene3D G3DSA:3.30.1360.20 1 92 7.1E-22 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MCR_1677 91f451b334095370f1328ecf6b20c85d 94 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 3 90 8.6E-20 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MCR_1677 91f451b334095370f1328ecf6b20c85d 94 SUPERFAMILY SSF55248 4 92 3.53E-22 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MCR_1868 1065c857ddd61390fbdc70935b8ecab8 301 Gene3D G3DSA:3.40.50.300 3 246 5.4E-63 T 14-10-2018 MCR_1868 1065c857ddd61390fbdc70935b8ecab8 301 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1868 1065c857ddd61390fbdc70935b8ecab8 301 SMART SM00382 31 217 1.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1868 1065c857ddd61390fbdc70935b8ecab8 301 SUPERFAMILY SSF52540 3 230 2.87E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1868 1065c857ddd61390fbdc70935b8ecab8 301 Pfam PF00005 ABC transporter 23 169 6.8E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1747 0e814edfd57883222504698a1e7a3a8e 218 Pfam PF01634 ATP phosphoribosyltransferase 60 209 5.3E-49 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MCR_1747 0e814edfd57883222504698a1e7a3a8e 218 Gene3D G3DSA:3.40.190.10 101 182 4.6E-72 T 14-10-2018 MCR_1747 0e814edfd57883222504698a1e7a3a8e 218 SUPERFAMILY SSF53850 11 216 1.85E-66 T 14-10-2018 MCR_1747 0e814edfd57883222504698a1e7a3a8e 218 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 149 170 - T 14-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 MCR_1747 0e814edfd57883222504698a1e7a3a8e 218 Gene3D G3DSA:3.40.190.10 12 203 4.6E-72 T 14-10-2018 MCR_1747 0e814edfd57883222504698a1e7a3a8e 218 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 10 214 54.736 T 14-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 MCR_1747 0e814edfd57883222504698a1e7a3a8e 218 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 11 190 9.5E-59 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MCR_0809 c09ac8654e75e595b7ee14aa693745cc 341 SUPERFAMILY SSF56529 83 339 1.2E-54 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MCR_0809 c09ac8654e75e595b7ee14aa693745cc 341 Gene3D G3DSA:3.90.850.10 13 341 9.5E-127 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MCR_0809 c09ac8654e75e595b7ee14aa693745cc 341 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 88 338 7.4E-43 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MCR_0723 5884571565bc84113685f21027160274 273 Gene3D G3DSA:2.40.30.10 1 113 2.0E-25 T 14-10-2018 MCR_0723 5884571565bc84113685f21027160274 273 SUPERFAMILY SSF52343 125 273 3.01E-33 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MCR_0723 5884571565bc84113685f21027160274 273 SUPERFAMILY SSF63380 6 118 8.78E-20 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MCR_0723 5884571565bc84113685f21027160274 273 Pfam PF00175 Oxidoreductase NAD-binding domain 133 249 2.0E-13 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MCR_0723 5884571565bc84113685f21027160274 273 Gene3D G3DSA:3.40.50.80 117 273 9.5E-38 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MCR_0723 5884571565bc84113685f21027160274 273 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 70 77 1.8E-8 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MCR_0723 5884571565bc84113685f21027160274 273 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 235 243 1.8E-8 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MCR_0723 5884571565bc84113685f21027160274 273 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 132 151 1.8E-8 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MCR_0723 5884571565bc84113685f21027160274 273 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 157 166 1.8E-8 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MCR_1077 f90f00a49c4f89dfcb93ef8edec66472 226 PIRSF PIRSF001461 1 226 5.1E-101 T 14-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MCR_1077 f90f00a49c4f89dfcb93ef8edec66472 226 SUPERFAMILY SSF51366 5 219 3.63E-73 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MCR_1077 f90f00a49c4f89dfcb93ef8edec66472 226 Pfam PF00834 Ribulose-phosphate 3 epimerase family 7 204 8.6E-86 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MCR_1077 f90f00a49c4f89dfcb93ef8edec66472 226 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 6 217 3.0E-95 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MCR_1077 f90f00a49c4f89dfcb93ef8edec66472 226 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 137 159 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MCR_1077 f90f00a49c4f89dfcb93ef8edec66472 226 Gene3D G3DSA:3.20.20.70 6 223 2.1E-80 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1077 f90f00a49c4f89dfcb93ef8edec66472 226 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 34 48 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 Gene3D G3DSA:1.10.150.20 561 616 4.6E-18 T 14-10-2018 MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 406 548 4.4E-47 T 14-10-2018 IPR001162 UvrC family homology region MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 SUPERFAMILY SSF82771 27 111 1.01E-21 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 Pfam PF12826 Helix-hairpin-helix motif 567 615 1.5E-6 T 14-10-2018 MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 Pfam PF02151 UvrB/uvrC motif 221 248 1.6E-8 T 14-10-2018 IPR001943 UVR domain GO:0005515 MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 SUPERFAMILY SSF46600 203 254 7.85E-11 T 14-10-2018 IPR036876 UVR domain superfamily MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 Pfam PF01541 GIY-YIG catalytic domain 30 104 1.2E-9 T 14-10-2018 IPR000305 GIY-YIG endonuclease MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 SUPERFAMILY SSF47781 515 615 1.49E-21 T 14-10-2018 IPR010994 RuvA domain 2-like MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 Gene3D G3DSA:3.30.420.340 389 558 7.0E-54 T 14-10-2018 IPR038476 UvrC homology region 2 superfamily MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 Gene3D G3DSA:3.40.1440.10 14 113 8.7E-34 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 Hamap MF_00203 UvrABC system protein C [uvrC]. 15 613 27.08 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 19 595 1.1E-176 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 MCR_0363 4b8ded799666383513aa9a615a9e5c4c 616 SMART SM00465 28 109 3.1E-23 T 14-10-2018 IPR000305 GIY-YIG endonuclease MCR_1032 040645d6cef10a75a7f2b2a977862cbd 284 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 14 274 2.7E-79 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MCR_1032 040645d6cef10a75a7f2b2a977862cbd 284 SMART SM00650 29 205 1.0E-73 T 14-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 MCR_1032 040645d6cef10a75a7f2b2a977862cbd 284 Gene3D G3DSA:1.10.8.100 208 279 2.6E-15 T 14-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 MCR_1032 040645d6cef10a75a7f2b2a977862cbd 284 SUPERFAMILY SSF53335 12 278 1.44E-71 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1032 040645d6cef10a75a7f2b2a977862cbd 284 Pfam PF00398 Ribosomal RNA adenine dimethylase 15 271 1.7E-59 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm MCR_1032 040645d6cef10a75a7f2b2a977862cbd 284 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 45 72 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 MCR_1032 040645d6cef10a75a7f2b2a977862cbd 284 Gene3D G3DSA:3.40.50.150 7 206 1.4E-64 T 14-10-2018 MCR_1032 040645d6cef10a75a7f2b2a977862cbd 284 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 13 277 53.039 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 9.8E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 9.8E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 9.8E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 Gene3D G3DSA:3.40.50.720 1 242 1.1E-82 T 14-10-2018 MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 2.7E-51 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.7E-51 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.7E-51 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.7E-51 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.7E-51 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.7E-51 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 240 2.4E-66 T 14-10-2018 MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 SUPERFAMILY SSF51735 4 242 4.74E-85 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 6 241 3.0E-99 T 14-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 181 1.3E-4 T 14-10-2018 MCR_1553 67432cd5f4eff83a59fe786c8186775c 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MCR_1754 07b176dc66250471681dfc73ea0efede 160 SUPERFAMILY SSF75217 1 156 3.19E-47 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MCR_1754 07b176dc66250471681dfc73ea0efede 160 Gene3D G3DSA:3.40.1280.10 1 158 1.7E-50 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MCR_1754 07b176dc66250471681dfc73ea0efede 160 Pfam PF02590 Predicted SPOUT methyltransferase 1 157 1.2E-48 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MCR_1754 07b176dc66250471681dfc73ea0efede 160 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 158 27.226 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MCR_1754 07b176dc66250471681dfc73ea0efede 160 PIRSF PIRSF004505 1 158 2.1E-45 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MCR_1754 07b176dc66250471681dfc73ea0efede 160 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 158 4.6E-48 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 284 291 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 Pfam PF02785 Biotin carboxylase C-terminal domain 334 440 2.8E-35 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.3E-43 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 SUPERFAMILY SSF56059 83 343 4.6E-70 T 14-10-2018 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 Gene3D G3DSA:3.30.470.20 87 430 4.0E-148 T 14-10-2018 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 Gene3D G3DSA:3.30.1490.20 131 201 4.0E-148 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 SUPERFAMILY SSF51246 329 442 4.24E-39 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 SUPERFAMILY SSF52440 1 113 7.91E-47 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MCR_0840 517a7f4fd060744faa533366b3b524ea 447 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 320 3.3E-77 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 Gene3D G3DSA:3.40.50.20 1 85 4.9E-34 T 14-10-2018 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 442 3.3E-206 T 14-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 MCR_0840 517a7f4fd060744faa533366b3b524ea 447 SMART SM00878 334 440 1.4E-56 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 ProSitePatterns PS00438 Catalase proximal active site signature. 50 66 - T 14-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 340 348 - T 14-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 Gene3D G3DSA:2.40.180.10 10 492 2.4E-222 T 14-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 Pfam PF06628 Catalase-related immune-responsive 422 483 1.6E-21 T 14-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 SMART SM01060 14 398 2.8E-278 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 PRINTS PR00067 Catalase signature 27 50 1.9E-68 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 PRINTS PR00067 Catalase signature 111 128 1.9E-68 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 PRINTS PR00067 Catalase signature 90 108 1.9E-68 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 PRINTS PR00067 Catalase signature 327 353 1.9E-68 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 PRINTS PR00067 Catalase signature 130 148 1.9E-68 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 PRINTS PR00067 Catalase signature 295 322 1.9E-68 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 SUPERFAMILY SSF56634 5 491 4.19E-209 T 14-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 Pfam PF00199 Catalase 14 395 6.6E-185 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_1464 45c1427841330a52ffad6fe0ade706ef 506 PIRSF PIRSF038928 3 489 2.9E-219 T 14-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MCR_0697 92654195a8cc1b5e4cb6707d7bb985e6 322 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 319 44.022 T 14-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 MCR_0697 92654195a8cc1b5e4cb6707d7bb985e6 322 PIRSF PIRSF006621 1 319 1.2E-70 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MCR_0697 92654195a8cc1b5e4cb6707d7bb985e6 322 Gene3D G3DSA:1.20.120.1460 248 318 3.1E-13 T 14-10-2018 MCR_0697 92654195a8cc1b5e4cb6707d7bb985e6 322 Pfam PF01207 Dihydrouridine synthase (Dus) 9 299 3.1E-75 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MCR_0697 92654195a8cc1b5e4cb6707d7bb985e6 322 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 5 304 5.1E-121 T 14-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 MCR_0697 92654195a8cc1b5e4cb6707d7bb985e6 322 Gene3D G3DSA:3.20.20.70 2 244 5.1E-73 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0697 92654195a8cc1b5e4cb6707d7bb985e6 322 SUPERFAMILY SSF51395 6 299 3.5E-63 T 14-10-2018 MCR_0414 a14fd0a4a3c2dd75634841f73f4472b9 182 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 22 175 31.75 T 14-10-2018 IPR033747 Class I PurE MCR_0414 a14fd0a4a3c2dd75634841f73f4472b9 182 SMART SM01001 20 171 1.0E-105 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MCR_0414 a14fd0a4a3c2dd75634841f73f4472b9 182 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 22 174 2.7E-65 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MCR_0414 a14fd0a4a3c2dd75634841f73f4472b9 182 SUPERFAMILY SSF52255 21 175 1.01E-65 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 MCR_0414 a14fd0a4a3c2dd75634841f73f4472b9 182 PIRSF PIRSF001338 17 177 1.3E-68 T 14-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 MCR_0414 a14fd0a4a3c2dd75634841f73f4472b9 182 Gene3D G3DSA:3.40.50.7700 12 178 6.5E-73 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 MCR_0414 a14fd0a4a3c2dd75634841f73f4472b9 182 Pfam PF00731 AIR carboxylase 21 169 5.8E-65 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 Gene3D G3DSA:2.20.28.10 22 80 5.8E-24 T 14-10-2018 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 Gene3D G3DSA:3.50.50.60 199 332 3.0E-64 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 115 2.3E-19 T 14-10-2018 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 191 209 2.3E-19 T 14-10-2018 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 347 369 2.3E-19 T 14-10-2018 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 254 2.3E-19 T 14-10-2018 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 SUPERFAMILY SSF51905 84 395 6.48E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 Pfam PF00301 Rubredoxin 29 74 5.2E-21 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 261 7.0E-13 T 14-10-2018 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 95 117 7.0E-13 T 14-10-2018 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 362 369 7.0E-13 T 14-10-2018 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 96 369 1.7E-39 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 SUPERFAMILY SSF57802 26 77 5.05E-19 T 14-10-2018 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 Gene3D G3DSA:3.50.50.60 97 369 3.0E-64 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 PRINTS PR00163 Rubredoxin signature 28 44 3.0E-8 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 PRINTS PR00163 Rubredoxin signature 58 74 3.0E-8 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 MCR_0041 e1c1ead2eba6f5b6483715c54d99758b 462 ProSitePatterns PS00202 Rubredoxin signature. 58 68 - T 14-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 SUPERFAMILY SSF47364 8 87 2.88E-19 T 14-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 SMART SM00963 13 94 2.1E-21 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 SMART SM00962 109 310 2.2E-120 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 SMART SM00382 108 255 1.1E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 38 309 1.7E-109 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 Pfam PF00448 SRP54-type protein, GTPase domain 110 309 1.1E-77 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 Gene3D G3DSA:1.20.120.140 10 308 2.2E-115 T 14-10-2018 MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 283 296 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 SUPERFAMILY SSF52540 104 310 4.8E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 37 310 60.858 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 Pfam PF02881 SRP54-type protein, helical bundle domain 25 90 1.9E-10 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MCR_0921 b05effa6e7582b4e6018adf0fe629daa 313 Gene3D G3DSA:3.40.50.300 109 298 2.2E-115 T 14-10-2018 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 SUPERFAMILY SSF52540 3 301 8.73E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 PIRSF PIRSF006641 1 363 1.0E-152 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 Gene3D G3DSA:3.40.50.300 4 278 6.6E-150 T 14-10-2018 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 5.3E-32 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 5.3E-32 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 5.3E-32 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 5.3E-32 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 Gene3D G3DSA:3.10.20.30 48 361 6.6E-150 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 SUPERFAMILY SSF81271 279 360 2.83E-36 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 44.314 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 8.8E-154 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 Gene3D G3DSA:1.10.150.300 113 200 6.6E-150 T 14-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 Pfam PF01926 50S ribosome-binding GTPase 5 124 1.6E-22 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_0830 7f4dff72a2061be56d8f03ac350e8b48 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 2.7E-39 T 14-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 MCR_0484 a2d030b46014100d76bfb55861890eac 148 Gene3D G3DSA:1.10.10.410 91 147 2.4E-16 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MCR_0484 a2d030b46014100d76bfb55861890eac 148 Pfam PF09424 Yqey-like protein 4 146 6.2E-46 T 14-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 MCR_0484 a2d030b46014100d76bfb55861890eac 148 Gene3D G3DSA:1.10.1510.10 1 90 3.8E-24 T 14-10-2018 MCR_0484 a2d030b46014100d76bfb55861890eac 148 SUPERFAMILY SSF89095 1 146 3.35E-37 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 MCR_1366 504fdb92fc7e5c14d55f6e66777b7cbc 332 Gene3D G3DSA:3.40.50.2300 56 302 2.3E-89 T 14-10-2018 MCR_1366 504fdb92fc7e5c14d55f6e66777b7cbc 332 SUPERFAMILY SSF53822 73 298 8.16E-16 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MCR_1366 504fdb92fc7e5c14d55f6e66777b7cbc 332 Pfam PF04392 ABC transporter substrate binding protein 39 330 2.0E-97 T 14-10-2018 IPR007487 ABC transporter, substrate-binding protein MCR_1366 504fdb92fc7e5c14d55f6e66777b7cbc 332 Gene3D G3DSA:3.40.50.2300 153 324 2.3E-89 T 14-10-2018 MCR_1303 4302479ec4f88ae7369597dcb2f6d09a 679 Gene3D G3DSA:3.90.76.10 70 196 6.3E-83 T 14-10-2018 MCR_1303 4302479ec4f88ae7369597dcb2f6d09a 679 SUPERFAMILY SSF53850 38 597 6.15E-76 T 14-10-2018 MCR_1303 4302479ec4f88ae7369597dcb2f6d09a 679 PIRSF PIRSF002741 1 321 3.8E-40 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MCR_1303 4302479ec4f88ae7369597dcb2f6d09a 679 PIRSF PIRSF002741 329 597 5.2E-8 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MCR_1303 4302479ec4f88ae7369597dcb2f6d09a 679 Gene3D G3DSA:3.10.105.10 305 585 6.3E-83 T 14-10-2018 MCR_1303 4302479ec4f88ae7369597dcb2f6d09a 679 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 517 4.9E-48 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MCR_1303 4302479ec4f88ae7369597dcb2f6d09a 679 Gene3D G3DSA:3.40.190.10 49 304 6.3E-83 T 14-10-2018 MCR_0072 b741d86ef3821b1cc0b8438e7b87ef2b 412 SUPERFAMILY SSF51230 2 90 3.93E-22 T 14-10-2018 IPR011053 Single hybrid motif MCR_0072 b741d86ef3821b1cc0b8438e7b87ef2b 412 Pfam PF00364 Biotin-requiring enzyme 3 74 3.8E-19 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MCR_0072 b741d86ef3821b1cc0b8438e7b87ef2b 412 SUPERFAMILY SSF52777 184 411 7.56E-90 T 14-10-2018 MCR_0072 b741d86ef3821b1cc0b8438e7b87ef2b 412 SUPERFAMILY SSF47005 125 163 1.96E-9 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MCR_0072 b741d86ef3821b1cc0b8438e7b87ef2b 412 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 183 409 1.2E-82 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MCR_0072 b741d86ef3821b1cc0b8438e7b87ef2b 412 Gene3D G3DSA:2.40.50.100 1 98 5.1E-20 T 14-10-2018 MCR_0072 b741d86ef3821b1cc0b8438e7b87ef2b 412 Gene3D G3DSA:3.30.559.10 180 412 1.0E-95 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MCR_0072 b741d86ef3821b1cc0b8438e7b87ef2b 412 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 411 5.3E-170 T 14-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MCR_0072 b741d86ef3821b1cc0b8438e7b87ef2b 412 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MCR_0072 b741d86ef3821b1cc0b8438e7b87ef2b 412 Gene3D G3DSA:4.10.320.10 117 165 2.7E-11 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MCR_0072 b741d86ef3821b1cc0b8438e7b87ef2b 412 Pfam PF02817 e3 binding domain 130 160 2.4E-12 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MCR_1264 34725318badd8602c271ee355000c76a 365 Gene3D G3DSA:2.40.50.140 28 107 6.0E-15 T 14-10-2018 MCR_1264 34725318badd8602c271ee355000c76a 365 SUPERFAMILY SSF52540 120 353 1.51E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1264 34725318badd8602c271ee355000c76a 365 Gene3D G3DSA:1.10.40.50 292 362 6.5E-14 T 14-10-2018 MCR_1264 34725318badd8602c271ee355000c76a 365 Pfam PF03193 RsgA GTPase 107 292 3.5E-46 T 14-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 MCR_1264 34725318badd8602c271ee355000c76a 365 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 86 350 3.7E-60 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MCR_1264 34725318badd8602c271ee355000c76a 365 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 31 357 30.271 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MCR_1264 34725318badd8602c271ee355000c76a 365 Gene3D G3DSA:3.40.50.300 109 291 1.0E-43 T 14-10-2018 MCR_0344 9abc04d7ce3440841d2c8e26076ff6a2 312 Gene3D G3DSA:3.30.700.10 216 311 6.1E-5 T 14-10-2018 MCR_0344 9abc04d7ce3440841d2c8e26076ff6a2 312 Pfam PF00114 Pilin (bacterial filament) 221 310 1.0E-4 T 14-10-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 MCR_0344 9abc04d7ce3440841d2c8e26076ff6a2 312 Pfam PF10947 Protein of unknown function (DUF2628) 30 146 8.2E-22 T 14-10-2018 IPR024399 Protein of unknown function DUF2628 MCR_1591 f7217bfc157b5afc92e53b20645eed63 313 Pfam PF13354 Beta-lactamase enzyme family 73 280 8.9E-36 T 14-10-2018 MCR_1591 f7217bfc157b5afc92e53b20645eed63 313 Gene3D G3DSA:3.40.710.10 47 313 1.3E-53 T 14-10-2018 MCR_1591 f7217bfc157b5afc92e53b20645eed63 313 SUPERFAMILY SSF56601 49 312 2.31E-59 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MCR_1591 f7217bfc157b5afc92e53b20645eed63 313 PRINTS PR00118 Beta-lactamase class A signature 225 240 1.2E-21 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MCR_1591 f7217bfc157b5afc92e53b20645eed63 313 PRINTS PR00118 Beta-lactamase class A signature 128 153 1.2E-21 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MCR_1591 f7217bfc157b5afc92e53b20645eed63 313 PRINTS PR00118 Beta-lactamase class A signature 84 101 1.2E-21 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MCR_1591 f7217bfc157b5afc92e53b20645eed63 313 PRINTS PR00118 Beta-lactamase class A signature 164 188 1.2E-21 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MCR_1591 f7217bfc157b5afc92e53b20645eed63 313 PRINTS PR00118 Beta-lactamase class A signature 189 214 1.2E-21 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MCR_1591 f7217bfc157b5afc92e53b20645eed63 313 PRINTS PR00118 Beta-lactamase class A signature 242 257 1.2E-21 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 344 353 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 471 56.568 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 2 471 6.2E-252 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 Gene3D G3DSA:1.10.1140.10 356 473 4.9E-60 T 14-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 Gene3D G3DSA:3.40.50.300 73 355 3.5E-114 T 14-10-2018 MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 Gene3D G3DSA:2.40.10.170 1 72 2.9E-29 T 14-10-2018 MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 SUPERFAMILY SSF52540 74 358 2.66E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 SMART SM00382 139 338 0.0019 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 SUPERFAMILY SSF50615 2 72 4.19E-24 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 5 70 2.2E-19 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 SUPERFAMILY SSF47917 356 472 9.16E-55 T 14-10-2018 MCR_0383 7998c13b1769dcdc4061e84f183bf3c3 473 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 127 353 8.4E-60 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MCR_0408 ad866cf56f0607a415e0230ac3ebe8ad 323 Gene3D G3DSA:3.30.930.10 3 323 1.1E-83 T 14-10-2018 MCR_0408 ad866cf56f0607a415e0230ac3ebe8ad 323 Pfam PF00152 tRNA synthetases class II (D, K and N) 13 317 4.9E-31 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0408 ad866cf56f0607a415e0230ac3ebe8ad 323 PRINTS PR00982 Lysyl-tRNA synthetase signature 29 39 4.4E-9 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_0408 ad866cf56f0607a415e0230ac3ebe8ad 323 PRINTS PR00982 Lysyl-tRNA synthetase signature 77 90 4.4E-9 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_0408 ad866cf56f0607a415e0230ac3ebe8ad 323 PRINTS PR00982 Lysyl-tRNA synthetase signature 95 112 4.4E-9 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_0408 ad866cf56f0607a415e0230ac3ebe8ad 323 PRINTS PR00982 Lysyl-tRNA synthetase signature 205 221 4.4E-9 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MCR_0408 ad866cf56f0607a415e0230ac3ebe8ad 323 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 15 317 7.2E-111 T 14-10-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 MCR_0408 ad866cf56f0607a415e0230ac3ebe8ad 323 SUPERFAMILY SSF55681 13 317 5.97E-61 T 14-10-2018 MCR_0553 194f0e23f74f60142a008e05d44344ee 382 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 382 2.9E-141 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MCR_0553 194f0e23f74f60142a008e05d44344ee 382 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 11 365 6.5E-97 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MCR_0553 194f0e23f74f60142a008e05d44344ee 382 PIRSF PIRSF000267 6 381 1.6E-113 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MCR_0756 846b78b2be454744f9e9be55b66a4e5b 164 Gene3D G3DSA:3.90.1170.40 25 163 9.0E-40 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MCR_0756 846b78b2be454744f9e9be55b66a4e5b 164 SUPERFAMILY SSF54690 37 162 6.28E-38 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MCR_0756 846b78b2be454744f9e9be55b66a4e5b 164 Pfam PF02391 MoaE protein 35 141 6.2E-31 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MCR_0027 6a5e1c61ac21e11ceff5fd69c69aa358 457 TIGRFAM TIGR02564 cas_Csy1: CRISPR type I-F/YPEST-associated protein Csy1 59 446 1.8E-84 T 14-10-2018 IPR013397 CRISPR-associated protein Csy1 MCR_0027 6a5e1c61ac21e11ceff5fd69c69aa358 457 Pfam PF09611 CRISPR-associated protein (Cas_Csy1) 59 438 2.5E-111 T 14-10-2018 IPR013397 CRISPR-associated protein Csy1 MCR_0099 646e9f00de55a8ffcc63c7a14d70277e 215 Gene3D G3DSA:2.60.120.10 20 162 5.0E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MCR_0099 646e9f00de55a8ffcc63c7a14d70277e 215 Pfam PF00027 Cyclic nucleotide-binding domain 60 138 6.1E-7 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain MCR_0099 646e9f00de55a8ffcc63c7a14d70277e 215 SUPERFAMILY SSF51206 35 164 3.54E-20 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 ProSitePatterns PS00177 DNA topoisomerase II signature. 435 443 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 18 815 1.1E-297 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 SMART SM00387 44 188 5.1E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 SUPERFAMILY SSF56719 407 814 5.23E-86 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 Gene3D G3DSA:3.30.565.10 15 232 2.2E-91 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 Gene3D G3DSA:3.40.50.670 412 608 1.4E-72 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 Gene3D G3DSA:3.30.230.10 233 411 5.5E-70 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 Pfam PF00204 DNA gyrase B 234 403 8.9E-59 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 SMART SM00433 48 813 3.0E-262 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR01159 DNA gyrase subunit B signature 773 785 1.2E-71 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR01159 DNA gyrase subunit B signature 387 407 1.2E-71 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR01159 DNA gyrase subunit B signature 373 387 1.2E-71 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR01159 DNA gyrase subunit B signature 209 222 1.2E-71 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR01159 DNA gyrase subunit B signature 483 492 1.2E-71 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR01159 DNA gyrase subunit B signature 233 255 1.2E-71 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR01159 DNA gyrase subunit B signature 194 209 1.2E-71 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR01159 DNA gyrase subunit B signature 325 341 1.2E-71 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR01159 DNA gyrase subunit B signature 789 805 1.2E-71 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR01159 DNA gyrase subunit B signature 18 28 1.2E-71 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 45 187 1.1E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 748 809 2.6E-29 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR00418 DNA topoisomerase II family signature 48 63 1.6E-71 T 14-10-2018 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR00418 DNA topoisomerase II family signature 83 96 1.6E-71 T 14-10-2018 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR00418 DNA topoisomerase II family signature 518 535 1.6E-71 T 14-10-2018 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR00418 DNA topoisomerase II family signature 433 447 1.6E-71 T 14-10-2018 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR00418 DNA topoisomerase II family signature 126 140 1.6E-71 T 14-10-2018 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR00418 DNA topoisomerase II family signature 752 768 1.6E-71 T 14-10-2018 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR00418 DNA topoisomerase II family signature 281 294 1.6E-71 T 14-10-2018 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR00418 DNA topoisomerase II family signature 500 516 1.6E-71 T 14-10-2018 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 PRINTS PR00418 DNA topoisomerase II family signature 538 550 1.6E-71 T 14-10-2018 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 Pfam PF01751 Toprim domain 432 544 6.1E-17 T 14-10-2018 IPR006171 TOPRIM domain MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 SUPERFAMILY SSF54211 234 405 6.26E-58 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 Gene3D G3DSA:3.40.50.670 721 818 1.2E-24 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 SUPERFAMILY SSF55874 18 229 1.96E-72 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 Gene3D G3DSA:3.10.20.690 609 699 4.5E-7 T 14-10-2018 MCR_0005 7a07864f91bb66b6a8c63b32d6a0c2b7 819 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 15 819 97.312 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_0196 6deb9a27006b5f4cb1a26b3dfb544d94 473 SUPERFAMILY SSF53955 31 325 1.39E-84 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MCR_0196 6deb9a27006b5f4cb1a26b3dfb544d94 473 Gene3D G3DSA:1.10.101.10 340 403 6.5E-12 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 MCR_0196 6deb9a27006b5f4cb1a26b3dfb544d94 473 SUPERFAMILY SSF47090 333 401 8.11E-15 T 14-10-2018 IPR036365 PGBD-like superfamily MCR_0196 6deb9a27006b5f4cb1a26b3dfb544d94 473 Pfam PF13406 Transglycosylase SLT domain 34 322 3.2E-94 T 14-10-2018 IPR031304 Transglycosylase SLT domain 2 MCR_0196 6deb9a27006b5f4cb1a26b3dfb544d94 473 Gene3D G3DSA:1.10.8.350 62 208 2.4E-77 T 14-10-2018 MCR_0196 6deb9a27006b5f4cb1a26b3dfb544d94 473 Pfam PF01471 Putative peptidoglycan binding domain 348 396 2.7E-9 T 14-10-2018 IPR002477 Peptidoglycan binding-like MCR_0196 6deb9a27006b5f4cb1a26b3dfb544d94 473 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 33 323 6.3E-98 T 14-10-2018 IPR011970 Lytic murein transglycosylase MCR_0196 6deb9a27006b5f4cb1a26b3dfb544d94 473 Gene3D G3DSA:1.10.530.10 75 321 2.4E-77 T 14-10-2018 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Gene3D G3DSA:3.30.470.90 88 333 2.5E-89 T 14-10-2018 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Gene3D G3DSA:2.40.50.140 334 406 1.1E-29 T 14-10-2018 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 338 414 3.7E-30 T 14-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 SMART SM00532 22 464 1.8E-227 T 14-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 24 334 1.8E-115 T 14-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 SUPERFAMILY SSF52113 610 686 8.22E-18 T 14-10-2018 IPR036420 BRCT domain superfamily MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 347 362 - T 14-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 SUPERFAMILY SSF50249 334 416 1.44E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Gene3D G3DSA:1.10.150.20 524 600 1.9E-27 T 14-10-2018 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 PIRSF PIRSF001604 14 690 1.7E-233 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 SMART SM00292 611 688 1.8E-9 T 14-10-2018 IPR001357 BRCT domain MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 133 162 - T 14-10-2018 IPR018239 NAD-dependent DNA ligase, active site MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 SUPERFAMILY SSF47781 420 602 5.19E-58 T 14-10-2018 IPR010994 RuvA domain 2-like MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Hamap MF_01588 DNA ligase [ligA]. 21 685 48.715 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 30 681 2.0E-234 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Gene3D G3DSA:1.10.150.20 448 523 8.0E-26 T 14-10-2018 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Gene3D G3DSA:1.10.287.610 11 86 4.6E-22 T 14-10-2018 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Pfam PF12826 Helix-hairpin-helix motif 528 591 8.2E-22 T 14-10-2018 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 424 450 3.0E-6 T 14-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 SMART SM00278 562 581 3.1 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 SMART SM00278 498 517 32.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 SMART SM00278 530 549 380.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 611 685 1.0E-9 T 14-10-2018 IPR001357 BRCT domain MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Gene3D G3DSA:3.40.50.10190 601 687 4.2E-24 T 14-10-2018 IPR036420 BRCT domain superfamily MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 Gene3D G3DSA:2.20.70.80 407 446 1.6E-14 T 14-10-2018 MCR_1715 3abc0ce80d5de87c364bf0cbb045b524 691 SUPERFAMILY SSF56091 21 332 1.44E-107 T 14-10-2018 MCR_0753 427c89488f1879c7574fac56b5d651f3 230 SUPERFAMILY SSF161098 6 221 7.33E-47 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0753 427c89488f1879c7574fac56b5d651f3 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 189 5.1E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_0753 427c89488f1879c7574fac56b5d651f3 230 Gene3D G3DSA:1.10.3720.10 1 226 4.2E-54 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0753 427c89488f1879c7574fac56b5d651f3 230 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 15 219 9.7E-67 T 14-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 MCR_1180 7c9ec8b98bf681a3ae2a168a126f57b3 268 SUPERFAMILY SSF51161 8 178 1.39E-50 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MCR_1180 7c9ec8b98bf681a3ae2a168a126f57b3 268 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 12 174 3.2E-71 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MCR_1180 7c9ec8b98bf681a3ae2a168a126f57b3 268 Pfam PF06426 Serine acetyltransferase, N-terminal 7 41 1.4E-4 T 14-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MCR_1180 7c9ec8b98bf681a3ae2a168a126f57b3 268 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 125 158 6.3E-8 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_1180 7c9ec8b98bf681a3ae2a168a126f57b3 268 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 79 115 6.6E-5 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_1180 7c9ec8b98bf681a3ae2a168a126f57b3 268 Gene3D G3DSA:1.10.3130.10 1 73 8.3E-23 T 14-10-2018 MCR_1180 7c9ec8b98bf681a3ae2a168a126f57b3 268 Gene3D G3DSA:2.160.10.10 74 201 3.2E-35 T 14-10-2018 MCR_1780 926483092c12169682a3005ef1728084 224 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 168 8.5E-13 T 14-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase MCR_0583 a28d4ad122f06c64e8fc2a4edd81d16d 83 Gene3D G3DSA:3.30.70.1680 1 60 9.8E-29 T 14-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 MCR_0583 a28d4ad122f06c64e8fc2a4edd81d16d 83 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 67 17.304 T 14-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 MCR_0583 a28d4ad122f06c64e8fc2a4edd81d16d 83 Pfam PF02599 Global regulator protein family 1 52 3.8E-26 T 14-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 MCR_0583 a28d4ad122f06c64e8fc2a4edd81d16d 83 SUPERFAMILY SSF117130 1 54 4.18E-20 T 14-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 MCR_0583 a28d4ad122f06c64e8fc2a4edd81d16d 83 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 1.0E-19 T 14-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 MCR_0583 a28d4ad122f06c64e8fc2a4edd81d16d 83 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 60 1.5E-29 T 14-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 MCR_1568 41378daabe3c4ced67a6638d53e3de45 165 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 10 162 1.9E-65 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MCR_1568 41378daabe3c4ced67a6638d53e3de45 165 Gene3D G3DSA:3.30.230.10 73 165 3.5E-37 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MCR_1568 41378daabe3c4ced67a6638d53e3de45 165 SUPERFAMILY SSF54211 78 158 4.8E-27 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1568 41378daabe3c4ced67a6638d53e3de45 165 ProSitePatterns PS00585 Ribosomal protein S5 signature. 27 59 - T 14-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site MCR_1568 41378daabe3c4ced67a6638d53e3de45 165 SUPERFAMILY SSF54768 6 75 1.78E-23 T 14-10-2018 MCR_1568 41378daabe3c4ced67a6638d53e3de45 165 Pfam PF03719 Ribosomal protein S5, C-terminal domain 86 156 6.9E-30 T 14-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 MCR_1568 41378daabe3c4ced67a6638d53e3de45 165 Pfam PF00333 Ribosomal protein S5, N-terminal domain 10 73 3.9E-28 T 14-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 MCR_1568 41378daabe3c4ced67a6638d53e3de45 165 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 162 34.122 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MCR_1568 41378daabe3c4ced67a6638d53e3de45 165 Gene3D G3DSA:3.30.160.20 1 72 9.5E-30 T 14-10-2018 MCR_1243 141fbc0f9ab74431383d2b7d81e97b2d 268 Gene3D G3DSA:3.30.70.580 2 107 4.4E-34 T 14-10-2018 MCR_1243 141fbc0f9ab74431383d2b7d81e97b2d 268 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 4 246 32.516 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1243 141fbc0f9ab74431383d2b7d81e97b2d 268 SUPERFAMILY SSF55120 3 251 3.45E-83 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1243 141fbc0f9ab74431383d2b7d81e97b2d 268 Gene3D G3DSA:3.30.70.660 108 244 2.0E-45 T 14-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 MCR_1243 141fbc0f9ab74431383d2b7d81e97b2d 268 Pfam PF01416 tRNA pseudouridine synthase 11 105 2.0E-6 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1243 141fbc0f9ab74431383d2b7d81e97b2d 268 Pfam PF01416 tRNA pseudouridine synthase 146 246 3.6E-27 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1243 141fbc0f9ab74431383d2b7d81e97b2d 268 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 6 240 9.2E-64 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1243 141fbc0f9ab74431383d2b7d81e97b2d 268 PIRSF PIRSF001430 3 255 6.1E-73 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1603 d5526252f74e43e34c3f6c6f392c1598 223 SUPERFAMILY SSF50715 4 198 1.4E-54 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MCR_1603 d5526252f74e43e34c3f6c6f392c1598 223 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 104 191 5.1E-29 T 14-10-2018 IPR020057 Ribosomal protein L25, beta domain MCR_1603 d5526252f74e43e34c3f6c6f392c1598 223 Gene3D G3DSA:2.170.120.20 101 199 1.2E-26 T 14-10-2018 IPR037121 Ribosomal protein L25, C-terminal MCR_1603 d5526252f74e43e34c3f6c6f392c1598 223 Pfam PF01386 Ribosomal L25p family 7 95 1.5E-25 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MCR_1603 d5526252f74e43e34c3f6c6f392c1598 223 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 188 29.69 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MCR_1603 d5526252f74e43e34c3f6c6f392c1598 223 Gene3D G3DSA:2.40.240.10 3 98 1.7E-29 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MCR_1603 d5526252f74e43e34c3f6c6f392c1598 223 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 14 179 3.3E-43 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MCR_1603 d5526252f74e43e34c3f6c6f392c1598 223 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 4 98 22.895 T 14-10-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MCR_1603 d5526252f74e43e34c3f6c6f392c1598 223 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 17 98 1.0E-29 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MCR_0881 1230be6fa305882c075e0e3ec31bf9c8 402 SUPERFAMILY SSF160996 206 341 1.11E-14 T 14-10-2018 MCR_0881 1230be6fa305882c075e0e3ec31bf9c8 402 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 27 398 1.1E-138 T 14-10-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 MCR_0881 1230be6fa305882c075e0e3ec31bf9c8 402 Pfam PF03486 HI0933-like protein 4 391 1.6E-80 T 14-10-2018 MCR_0881 1230be6fa305882c075e0e3ec31bf9c8 402 Gene3D G3DSA:2.40.30.10 193 340 2.3E-58 T 14-10-2018 MCR_0881 1230be6fa305882c075e0e3ec31bf9c8 402 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 391 8.3E-75 T 14-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like MCR_0881 1230be6fa305882c075e0e3ec31bf9c8 402 Gene3D G3DSA:3.50.50.60 5 390 2.3E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0881 1230be6fa305882c075e0e3ec31bf9c8 402 SUPERFAMILY SSF51905 1 395 7.6E-34 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0881 1230be6fa305882c075e0e3ec31bf9c8 402 Gene3D G3DSA:1.10.8.260 270 323 2.3E-58 T 14-10-2018 IPR023166 HI0933-like insert domain superfamily MCR_0938 5c79f2157dadbcc39756a2b1b097b57a 240 SUPERFAMILY SSF51306 100 234 1.57E-16 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MCR_0938 5c79f2157dadbcc39756a2b1b097b57a 240 Pfam PF00717 Peptidase S24-like 151 208 4.5E-9 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MCR_0938 5c79f2157dadbcc39756a2b1b097b57a 240 Gene3D G3DSA:2.10.109.10 114 240 1.8E-9 T 14-10-2018 MCR_0356 dca0b35f51850df2939301eb91cc061e 213 Pfam PF03458 UPF0126 domain 101 173 1.0E-21 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 MCR_0356 dca0b35f51850df2939301eb91cc061e 213 Pfam PF03458 UPF0126 domain 16 88 4.0E-17 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 MCR_0416 7bdfece669a657a3098cb76a2141444e 254 SUPERFAMILY SSF55120 8 248 4.8E-61 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0416 7bdfece669a657a3098cb76a2141444e 254 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 61 75 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0416 7bdfece669a657a3098cb76a2141444e 254 Gene3D G3DSA:3.30.2350.10 5 236 1.0E-60 T 14-10-2018 MCR_0416 7bdfece669a657a3098cb76a2141444e 254 Pfam PF00849 RNA pseudouridylate synthase 22 181 2.1E-32 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0395 294af01c5b0de2e716e2b950e0c5111a 571 Hamap MF_00577 Urocanate hydratase [hutU]. 1 571 48.853 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_0395 294af01c5b0de2e716e2b950e0c5111a 571 Pfam PF17391 Urocanase N-terminal domain 13 139 7.3E-60 T 14-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_0395 294af01c5b0de2e716e2b950e0c5111a 571 SUPERFAMILY SSF111326 7 570 7.72E-247 T 14-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_0395 294af01c5b0de2e716e2b950e0c5111a 571 Gene3D G3DSA:3.40.1770.10 18 557 8.2E-242 T 14-10-2018 MCR_0395 294af01c5b0de2e716e2b950e0c5111a 571 TIGRFAM TIGR01228 hutU: urocanate hydratase 12 569 6.1E-276 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_0395 294af01c5b0de2e716e2b950e0c5111a 571 PIRSF PIRSF001423 1 571 4.8E-281 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_0395 294af01c5b0de2e716e2b950e0c5111a 571 Pfam PF17392 Urocanase C-terminal domain 367 561 1.2E-91 T 14-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_0395 294af01c5b0de2e716e2b950e0c5111a 571 Gene3D G3DSA:3.40.50.10730 143 364 8.2E-242 T 14-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_0395 294af01c5b0de2e716e2b950e0c5111a 571 Pfam PF01175 Urocanase Rossmann-like domain 142 364 1.1E-76 T 14-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 PRINTS PR00145 Argininosuccinate lyase family signature 236 260 2.9E-68 T 14-10-2018 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 PRINTS PR00145 Argininosuccinate lyase family signature 280 296 2.9E-68 T 14-10-2018 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 PRINTS PR00145 Argininosuccinate lyase family signature 315 334 2.9E-68 T 14-10-2018 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 PRINTS PR00145 Argininosuccinate lyase family signature 106 128 2.9E-68 T 14-10-2018 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 PRINTS PR00145 Argininosuccinate lyase family signature 147 167 2.9E-68 T 14-10-2018 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 PRINTS PR00145 Argininosuccinate lyase family signature 198 214 2.9E-68 T 14-10-2018 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 Pfam PF14698 Argininosuccinate lyase C-terminal 368 435 1.8E-24 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 Gene3D G3DSA:1.10.40.30 365 437 2.6E-189 T 14-10-2018 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 SUPERFAMILY SSF48557 8 459 1.35E-152 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 Pfam PF00206 Lyase 11 305 4.6E-79 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 Hamap MF_00006 Argininosuccinate lyase [argH]. 7 458 43.293 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 TIGRFAM TIGR00838 argH: argininosuccinate lyase 8 459 5.5E-191 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 Gene3D G3DSA:1.10.275.10 30 234 2.6E-189 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 PRINTS PR00149 Fumarate lyase superfamily signature 236 263 1.3E-29 T 14-10-2018 IPR000362 Fumarate lyase family MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 1.3E-29 T 14-10-2018 IPR000362 Fumarate lyase family MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 PRINTS PR00149 Fumarate lyase superfamily signature 152 170 1.3E-29 T 14-10-2018 IPR000362 Fumarate lyase family MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 PRINTS PR00149 Fumarate lyase superfamily signature 107 125 1.3E-29 T 14-10-2018 IPR000362 Fumarate lyase family MCR_0017 2707d81f90a7840bf591f11aa93f21cb 466 Gene3D G3DSA:1.20.200.10 124 452 2.6E-189 T 14-10-2018 MCR_0874 043caf3029f8b38ff9d1c7032bf385d2 648 Pfam PF01266 FAD dependent oxidoreductase 266 617 1.0E-26 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MCR_0874 043caf3029f8b38ff9d1c7032bf385d2 648 Gene3D G3DSA:3.50.50.60 267 637 5.8E-76 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0874 043caf3029f8b38ff9d1c7032bf385d2 648 SUPERFAMILY SSF51905 265 637 2.85E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0874 043caf3029f8b38ff9d1c7032bf385d2 648 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 266 591 9.2E-52 T 14-10-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 MCR_0874 043caf3029f8b38ff9d1c7032bf385d2 648 Gene3D G3DSA:3.30.9.10 348 577 5.8E-76 T 14-10-2018 MCR_0874 043caf3029f8b38ff9d1c7032bf385d2 648 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 123 246 7.6E-40 T 14-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 MCR_0874 043caf3029f8b38ff9d1c7032bf385d2 648 Gene3D G3DSA:3.40.50.150 8 255 9.0E-89 T 14-10-2018 MCR_0874 043caf3029f8b38ff9d1c7032bf385d2 648 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 6 641 21.343 T 14-10-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 MCR_0015 a7e4a92a24c26bbd0fce7966683d94eb 623 Pfam PF01964 Radical SAM ThiC family 146 590 1.7E-205 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MCR_0015 a7e4a92a24c26bbd0fce7966683d94eb 623 Gene3D G3DSA:3.20.20.540 214 526 5.1E-156 T 14-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MCR_0015 a7e4a92a24c26bbd0fce7966683d94eb 623 Pfam PF13667 ThiC-associated domain 27 106 8.5E-33 T 14-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MCR_0015 a7e4a92a24c26bbd0fce7966683d94eb 623 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 145 595 100.712 T 14-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MCR_0015 a7e4a92a24c26bbd0fce7966683d94eb 623 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 145 593 1.4E-219 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MCR_1346 5f3e7b6f7c1a134cd6e998704e9f4e64 1296 SUPERFAMILY SSF52540 1135 1279 2.09E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1346 5f3e7b6f7c1a134cd6e998704e9f4e64 1296 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 225 935 6.0E-4 T 14-10-2018 MCR_1346 5f3e7b6f7c1a134cd6e998704e9f4e64 1296 SUPERFAMILY SSF52540 1 282 1.19E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1346 5f3e7b6f7c1a134cd6e998704e9f4e64 1296 Gene3D G3DSA:3.40.50.300 1 298 1.2E-42 T 14-10-2018 MCR_1346 5f3e7b6f7c1a134cd6e998704e9f4e64 1296 Pfam PF13476 AAA domain 5 269 8.9E-28 T 14-10-2018 IPR038729 Rad50/SbcC-type AAA domain MCR_1346 5f3e7b6f7c1a134cd6e998704e9f4e64 1296 Gene3D G3DSA:3.40.50.300 1025 1288 3.4E-22 T 14-10-2018 MCR_1346 5f3e7b6f7c1a134cd6e998704e9f4e64 1296 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1180 1248 8.0E-12 T 14-10-2018 MCR_0220 8849ecb43fb6c691ba0a60f19ed3b45c 541 Pfam PF04575 Protein of unknown function (DUF560) 255 541 5.8E-83 T 14-10-2018 IPR007655 Protein of unknown function DUF560 MCR_0220 8849ecb43fb6c691ba0a60f19ed3b45c 541 Gene3D G3DSA:1.25.40.10 161 234 1.2E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0188 0133212457813e37c570f73f9b25e236 421 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 11 404 6.5E-94 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MCR_0188 0133212457813e37c570f73f9b25e236 421 SUPERFAMILY SSF51735 150 313 5.65E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0188 0133212457813e37c570f73f9b25e236 421 SUPERFAMILY SSF69075 315 410 1.23E-14 T 14-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MCR_0188 0133212457813e37c570f73f9b25e236 421 Gene3D G3DSA:3.30.460.30 1 145 1.5E-33 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MCR_0188 0133212457813e37c570f73f9b25e236 421 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 3 143 1.5E-31 T 14-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MCR_0188 0133212457813e37c570f73f9b25e236 421 PIRSF PIRSF000445 1 419 4.1E-115 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MCR_0188 0133212457813e37c570f73f9b25e236 421 SUPERFAMILY SSF69742 11 145 1.83E-30 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MCR_0188 0133212457813e37c570f73f9b25e236 421 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 318 410 1.3E-10 T 14-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MCR_0188 0133212457813e37c570f73f9b25e236 421 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 4 416 21.206 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MCR_0188 0133212457813e37c570f73f9b25e236 421 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 159 304 8.9E-33 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MCR_0188 0133212457813e37c570f73f9b25e236 421 Gene3D G3DSA:3.40.50.720 149 310 2.9E-35 T 14-10-2018 MCR_1736 6d13adce7bc0acd479a89fb54c09c39c 106 Pfam PF01722 BolA-like protein 14 89 7.6E-24 T 14-10-2018 IPR002634 BolA protein MCR_1736 6d13adce7bc0acd479a89fb54c09c39c 106 SUPERFAMILY SSF82657 5 93 1.44E-21 T 14-10-2018 IPR036065 BolA-like superfamily MCR_1736 6d13adce7bc0acd479a89fb54c09c39c 106 Gene3D G3DSA:3.30.300.90 2 93 2.2E-23 T 14-10-2018 MCR_1736 6d13adce7bc0acd479a89fb54c09c39c 106 PIRSF PIRSF003113 1 104 9.5E-26 T 14-10-2018 IPR002634 BolA protein MCR_1054 f8ac686e2d54081d778f055c9255c60b 695 Pfam PF01807 CHC2 zinc finger 4 98 3.0E-33 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MCR_1054 f8ac686e2d54081d778f055c9255c60b 695 SUPERFAMILY SSF56731 192 480 3.79E-90 T 14-10-2018 MCR_1054 f8ac686e2d54081d778f055c9255c60b 695 SUPERFAMILY SSF57783 1 98 1.11E-32 T 14-10-2018 MCR_1054 f8ac686e2d54081d778f055c9255c60b 695 Gene3D G3DSA:3.40.1360.10 314 438 2.5E-38 T 14-10-2018 MCR_1054 f8ac686e2d54081d778f055c9255c60b 695 Pfam PF08275 DNA primase catalytic core, N-terminal domain 204 324 4.3E-33 T 14-10-2018 IPR013264 DNA primase, catalytic core, N-terminal MCR_1054 f8ac686e2d54081d778f055c9255c60b 695 Hamap MF_00974 DNA primase [dnaG]. 2 694 25.235 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MCR_1054 f8ac686e2d54081d778f055c9255c60b 695 Pfam PF13155 Toprim-like 334 421 1.4E-15 T 14-10-2018 MCR_1054 f8ac686e2d54081d778f055c9255c60b 695 Gene3D G3DSA:3.90.980.10 186 313 1.6E-32 T 14-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily MCR_1054 f8ac686e2d54081d778f055c9255c60b 695 Gene3D G3DSA:3.90.580.10 1 101 4.7E-36 T 14-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 MCR_1054 f8ac686e2d54081d778f055c9255c60b 695 SMART SM00400 34 88 1.9E-27 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MCR_1054 f8ac686e2d54081d778f055c9255c60b 695 SMART SM00493 330 401 4.3E-14 T 14-10-2018 IPR006171 TOPRIM domain MCR_0360 95f4f9df2e2e111a692dc77b3cfe8795 658 SUPERFAMILY SSF53335 119 509 5.82E-58 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0360 95f4f9df2e2e111a692dc77b3cfe8795 658 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 217 236 6.7E-13 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MCR_0360 95f4f9df2e2e111a692dc77b3cfe8795 658 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 151 163 6.7E-13 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MCR_0360 95f4f9df2e2e111a692dc77b3cfe8795 658 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 455 469 6.7E-13 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MCR_0360 95f4f9df2e2e111a692dc77b3cfe8795 658 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 432 454 6.7E-13 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MCR_0360 95f4f9df2e2e111a692dc77b3cfe8795 658 Pfam PF04886 PT repeat 7 39 2.0E-10 T 14-10-2018 IPR006970 PT repeat MCR_0360 95f4f9df2e2e111a692dc77b3cfe8795 658 PIRSF PIRSF015855 13 658 1.3E-181 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MCR_0360 95f4f9df2e2e111a692dc77b3cfe8795 658 Pfam PF01555 DNA methylase 151 483 4.6E-39 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 MCR_0360 95f4f9df2e2e111a692dc77b3cfe8795 658 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 154 160 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MCR_0923 7358d182a5b7fd634496657ccd9d77fa 341 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 291 311 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MCR_0923 7358d182a5b7fd634496657ccd9d77fa 341 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 79 98 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MCR_0923 7358d182a5b7fd634496657ccd9d77fa 341 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 335 47.708 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MCR_0923 7358d182a5b7fd634496657ccd9d77fa 341 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 3 335 1.8E-125 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MCR_0923 7358d182a5b7fd634496657ccd9d77fa 341 SUPERFAMILY SSF51395 1 335 5.0E-97 T 14-10-2018 MCR_0923 7358d182a5b7fd634496657ccd9d77fa 341 Pfam PF01180 Dihydroorotate dehydrogenase 44 335 1.2E-80 T 14-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MCR_0923 7358d182a5b7fd634496657ccd9d77fa 341 Gene3D G3DSA:3.20.20.70 3 334 4.1E-122 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0923 7358d182a5b7fd634496657ccd9d77fa 341 PIRSF PIRSF000164 9 337 1.1E-89 T 14-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 MCR_1385 c91bb5a96299233993131e3eb4a16f7d 442 PRINTS PR01486 Bacterial phospholipase A1 protein signature 224 241 1.7E-24 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MCR_1385 c91bb5a96299233993131e3eb4a16f7d 442 PRINTS PR01486 Bacterial phospholipase A1 protein signature 387 404 1.7E-24 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MCR_1385 c91bb5a96299233993131e3eb4a16f7d 442 PRINTS PR01486 Bacterial phospholipase A1 protein signature 246 262 1.7E-24 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MCR_1385 c91bb5a96299233993131e3eb4a16f7d 442 PRINTS PR01486 Bacterial phospholipase A1 protein signature 353 371 1.7E-24 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MCR_1385 c91bb5a96299233993131e3eb4a16f7d 442 PRINTS PR01486 Bacterial phospholipase A1 protein signature 409 429 1.7E-24 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MCR_1385 c91bb5a96299233993131e3eb4a16f7d 442 PRINTS PR01486 Bacterial phospholipase A1 protein signature 269 288 1.7E-24 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MCR_1385 c91bb5a96299233993131e3eb4a16f7d 442 SUPERFAMILY SSF56931 186 440 9.02E-78 T 14-10-2018 IPR036541 Phospholipase A1 superfamily GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MCR_1385 c91bb5a96299233993131e3eb4a16f7d 442 Pfam PF02253 Phospholipase A1 186 436 3.0E-86 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MCR_1385 c91bb5a96299233993131e3eb4a16f7d 442 Gene3D G3DSA:2.40.230.10 173 440 4.1E-82 T 14-10-2018 IPR036541 Phospholipase A1 superfamily GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 Gene3D G3DSA:3.40.50.300 1 219 2.4E-77 T 14-10-2018 MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 TIGRFAM TIGR01351 adk: adenylate kinase 3 216 1.5E-73 T 14-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 Pfam PF00406 Adenylate kinase 6 186 2.9E-55 T 14-10-2018 MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 SUPERFAMILY SSF52540 2 216 4.71E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 Hamap MF_00235 Adenylate kinase [adk]. 2 217 51.287 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 PRINTS PR00094 Adenylate kinase signature 174 188 5.8E-31 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 PRINTS PR00094 Adenylate kinase signature 82 98 5.8E-31 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 PRINTS PR00094 Adenylate kinase signature 5 18 5.8E-31 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 PRINTS PR00094 Adenylate kinase signature 33 47 5.8E-31 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 PRINTS PR00094 Adenylate kinase signature 157 172 5.8E-31 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 14-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MCR_1233 106e8d2b7e57c8235a186a4b6f93b634 219 Pfam PF05191 Adenylate kinase, active site lid 124 159 9.0E-15 T 14-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MCR_1439 24d27a5f3191008c88b84452289f7663 473 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 44 472 1.3E-128 T 14-10-2018 IPR013355 Type IV pilus secretin PilQ MCR_1439 24d27a5f3191008c88b84452289f7663 473 PRINTS PR00811 Bacterial general secretion pathway protein D signature 315 339 6.1E-20 T 14-10-2018 IPR001775 GspD/PilQ family MCR_1439 24d27a5f3191008c88b84452289f7663 473 PRINTS PR00811 Bacterial general secretion pathway protein D signature 460 473 6.1E-20 T 14-10-2018 IPR001775 GspD/PilQ family MCR_1439 24d27a5f3191008c88b84452289f7663 473 PRINTS PR00811 Bacterial general secretion pathway protein D signature 230 240 6.1E-20 T 14-10-2018 IPR001775 GspD/PilQ family MCR_1439 24d27a5f3191008c88b84452289f7663 473 PRINTS PR00811 Bacterial general secretion pathway protein D signature 437 455 6.1E-20 T 14-10-2018 IPR001775 GspD/PilQ family MCR_1439 24d27a5f3191008c88b84452289f7663 473 Pfam PF00263 Bacterial type II and III secretion system protein 319 473 2.8E-45 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 MCR_1439 24d27a5f3191008c88b84452289f7663 473 Gene3D G3DSA:3.55.50.30 20 128 2.6E-30 T 14-10-2018 MCR_1439 24d27a5f3191008c88b84452289f7663 473 Pfam PF03958 Bacterial type II/III secretion system short domain 128 230 4.2E-11 T 14-10-2018 IPR005644 NolW-like MCR_1439 24d27a5f3191008c88b84452289f7663 473 SMART SM00965 69 117 0.0013 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MCR_1439 24d27a5f3191008c88b84452289f7663 473 Gene3D G3DSA:3.30.1370.120 129 229 1.7E-11 T 14-10-2018 IPR038591 NolW-like superfamily MCR_0052 9225983093d233a1eb652f8a29449b74 333 Gene3D G3DSA:3.40.30.10 178 331 3.0E-19 T 14-10-2018 MCR_0052 9225983093d233a1eb652f8a29449b74 333 SUPERFAMILY SSF52833 190 330 9.52E-15 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0052 9225983093d233a1eb652f8a29449b74 333 Pfam PF13098 Thioredoxin-like domain 204 329 1.7E-10 T 14-10-2018 IPR012336 Thioredoxin-like fold MCR_1181 297de3233ed938bba52fdc1cb0a10cbe 207 SUPERFAMILY SSF48150 10 192 1.33E-73 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MCR_1181 297de3233ed938bba52fdc1cb0a10cbe 207 Gene3D G3DSA:1.10.340.30 9 194 8.8E-78 T 14-10-2018 MCR_1181 297de3233ed938bba52fdc1cb0a10cbe 207 Pfam PF03352 Methyladenine glycosylase 14 191 6.7E-75 T 14-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 MCR_0722 fcedc8d47f49164692b9a1ae73e760e4 249 Pfam PF00462 Glutaredoxin 174 232 7.6E-16 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MCR_0722 fcedc8d47f49164692b9a1ae73e760e4 249 Pfam PF08534 Redoxin 7 161 5.4E-33 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MCR_0722 fcedc8d47f49164692b9a1ae73e760e4 249 TIGRFAM TIGR02190 GlrX-dom: glutaredoxin-family domain 165 243 1.4E-35 T 14-10-2018 IPR011906 Glutaredoxin domain KEGG: 00480+1.11.1.15 MCR_0722 fcedc8d47f49164692b9a1ae73e760e4 249 PRINTS PR00160 Glutaredoxin signature 215 228 1.8E-10 T 14-10-2018 IPR014025 Glutaredoxin subgroup MCR_0722 fcedc8d47f49164692b9a1ae73e760e4 249 PRINTS PR00160 Glutaredoxin signature 229 242 1.8E-10 T 14-10-2018 IPR014025 Glutaredoxin subgroup MCR_0722 fcedc8d47f49164692b9a1ae73e760e4 249 PRINTS PR00160 Glutaredoxin signature 174 192 1.8E-10 T 14-10-2018 IPR014025 Glutaredoxin subgroup MCR_0722 fcedc8d47f49164692b9a1ae73e760e4 249 Gene3D G3DSA:3.40.30.10 173 243 2.8E-20 T 14-10-2018 MCR_0722 fcedc8d47f49164692b9a1ae73e760e4 249 Gene3D G3DSA:3.40.30.10 6 166 1.2E-61 T 14-10-2018 MCR_0722 fcedc8d47f49164692b9a1ae73e760e4 249 SUPERFAMILY SSF52833 7 242 3.42E-43 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0121 24aca9044dd968a0ca056ba2bfd09042 323 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 17 319 45.378 T 14-10-2018 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 MCR_0121 24aca9044dd968a0ca056ba2bfd09042 323 PIRSF PIRSF006621 1 322 3.9E-69 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MCR_0121 24aca9044dd968a0ca056ba2bfd09042 323 Gene3D G3DSA:3.20.20.70 11 252 2.7E-65 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0121 24aca9044dd968a0ca056ba2bfd09042 323 Pfam PF01207 Dihydrouridine synthase (Dus) 14 305 5.4E-59 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MCR_0121 24aca9044dd968a0ca056ba2bfd09042 323 Gene3D G3DSA:1.20.225.30 255 321 1.3E-8 T 14-10-2018 MCR_0121 24aca9044dd968a0ca056ba2bfd09042 323 SUPERFAMILY SSF51395 13 314 3.02E-59 T 14-10-2018 MCR_0121 24aca9044dd968a0ca056ba2bfd09042 323 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 106 124 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MCR_0763 5359977f1f77b3b13ff470baa2fb2cad 218 Gene3D G3DSA:3.40.50.12740 13 217 5.4E-62 T 14-10-2018 MCR_0763 5359977f1f77b3b13ff470baa2fb2cad 218 SMART SM00421 156 213 4.9E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_0763 5359977f1f77b3b13ff470baa2fb2cad 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_0763 5359977f1f77b3b13ff470baa2fb2cad 218 SUPERFAMILY SSF52172 11 141 2.13E-32 T 14-10-2018 IPR011006 CheY-like superfamily MCR_0763 5359977f1f77b3b13ff470baa2fb2cad 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 7.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_0763 5359977f1f77b3b13ff470baa2fb2cad 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 7.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_0763 5359977f1f77b3b13ff470baa2fb2cad 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 7.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_0763 5359977f1f77b3b13ff470baa2fb2cad 218 SMART SM00448 12 125 4.8E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_0763 5359977f1f77b3b13ff470baa2fb2cad 218 SUPERFAMILY SSF46894 153 216 8.84E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MCR_0763 5359977f1f77b3b13ff470baa2fb2cad 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 213 5.9E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MCR_0763 5359977f1f77b3b13ff470baa2fb2cad 218 Pfam PF00072 Response regulator receiver domain 15 125 3.0E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 SMART SM00388 255 313 5.5E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 307 1.6E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 SMART SM00387 349 471 3.0E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 SUPERFAMILY SSF55874 317 472 1.44E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 426 2.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 468 2.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 412 2.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 2.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 469 8.9E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 Gene3D G3DSA:3.30.565.10 316 477 3.9E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 SUPERFAMILY SSF47384 240 309 6.47E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MCR_0387 ea72b2bb3f44e0142f7ed91f1d2e3963 489 Gene3D G3DSA:1.10.287.130 198 308 2.8E-16 T 14-10-2018 MCR_1284 a8e440bde776ac5849bfd4119486794c 528 Pfam PF02554 Carbon starvation protein CstA 4 327 1.0E-44 T 14-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 MCR_1284 a8e440bde776ac5849bfd4119486794c 528 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 365 474 3.4E-20 T 14-10-2018 IPR025299 CstA, C-terminal domain MCR_0207 12de8a5f636a40e0d746258a6a62b395 245 Pfam PF01738 Dienelactone hydrolase family 30 243 9.7E-50 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 MCR_0207 12de8a5f636a40e0d746258a6a62b395 245 SUPERFAMILY SSF53474 5 245 1.47E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0207 12de8a5f636a40e0d746258a6a62b395 245 Gene3D G3DSA:3.40.50.1820 1 245 7.5E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 Pfam PF13089 Polyphosphate kinase N-terminal domain 63 168 3.7E-33 T 14-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 PIRSF PIRSF015589 36 739 2.9E-264 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 Pfam PF02503 Polyphosphate kinase middle domain 177 375 1.3E-60 T 14-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 SUPERFAMILY SSF140356 60 164 9.68E-34 T 14-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 Gene3D G3DSA:3.30.870.10 563 738 6.7E-63 T 14-10-2018 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 Hamap MF_00347 Polyphosphate kinase [ppk]. 60 740 27.125 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 Gene3D G3DSA:3.30.870.10 376 559 3.5E-67 T 14-10-2018 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 Gene3D G3DSA:3.30.1840.10 57 367 1.5E-99 T 14-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 SUPERFAMILY SSF143724 166 367 5.89E-63 T 14-10-2018 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 63 736 6.0E-270 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 SUPERFAMILY SSF56024 560 734 3.14E-66 T 14-10-2018 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 SUPERFAMILY SSF56024 383 554 4.08E-53 T 14-10-2018 MCR_1157 2c8c6fcf42e367a1fa7d366cc8136b24 740 Pfam PF13090 Polyphosphate kinase C-terminal domain 389 722 2.9E-144 T 14-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 MCR_1241 0f5ed9526d3a568b0d42e246e95551ec 377 Gene3D G3DSA:3.40.50.720 4 143 6.3E-57 T 14-10-2018 MCR_1241 0f5ed9526d3a568b0d42e246e95551ec 377 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 151 360 2.8E-54 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MCR_1241 0f5ed9526d3a568b0d42e246e95551ec 377 Gene3D G3DSA:3.30.360.10 144 357 3.3E-77 T 14-10-2018 MCR_1241 0f5ed9526d3a568b0d42e246e95551ec 377 SUPERFAMILY SSF51735 5 151 5.38E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1241 0f5ed9526d3a568b0d42e246e95551ec 377 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 5 373 3.1E-179 T 14-10-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MCR_1241 0f5ed9526d3a568b0d42e246e95551ec 377 SUPERFAMILY SSF55347 138 361 2.23E-72 T 14-10-2018 MCR_1241 0f5ed9526d3a568b0d42e246e95551ec 377 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 126 2.2E-22 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MCR_1241 0f5ed9526d3a568b0d42e246e95551ec 377 PIRSF PIRSF000148 4 377 2.5E-65 T 14-10-2018 MCR_1241 0f5ed9526d3a568b0d42e246e95551ec 377 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 267 281 - T 14-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MCR_1241 0f5ed9526d3a568b0d42e246e95551ec 377 SMART SM00859 6 126 3.2E-22 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MCR_1853 56817e303791b0998adb7e550ce7d8ca 184 Hamap MF_00163 Peptide deformylase [def]. 2 165 31.266 T 14-10-2018 IPR023635 Peptide deformylase MCR_1853 56817e303791b0998adb7e550ce7d8ca 184 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 163 1.3E-54 T 14-10-2018 IPR023635 Peptide deformylase MCR_1853 56817e303791b0998adb7e550ce7d8ca 184 PRINTS PR01576 Peptide deformylase signature 104 122 7.2E-39 T 14-10-2018 IPR023635 Peptide deformylase MCR_1853 56817e303791b0998adb7e550ce7d8ca 184 PRINTS PR01576 Peptide deformylase signature 123 152 7.2E-39 T 14-10-2018 IPR023635 Peptide deformylase MCR_1853 56817e303791b0998adb7e550ce7d8ca 184 PRINTS PR01576 Peptide deformylase signature 92 103 7.2E-39 T 14-10-2018 IPR023635 Peptide deformylase MCR_1853 56817e303791b0998adb7e550ce7d8ca 184 PRINTS PR01576 Peptide deformylase signature 33 62 7.2E-39 T 14-10-2018 IPR023635 Peptide deformylase MCR_1853 56817e303791b0998adb7e550ce7d8ca 184 Pfam PF01327 Polypeptide deformylase 5 155 5.3E-54 T 14-10-2018 IPR023635 Peptide deformylase MCR_1853 56817e303791b0998adb7e550ce7d8ca 184 PIRSF PIRSF004749 1 180 2.1E-57 T 14-10-2018 IPR023635 Peptide deformylase MCR_1853 56817e303791b0998adb7e550ce7d8ca 184 Gene3D G3DSA:3.90.45.10 1 170 1.6E-63 T 14-10-2018 IPR036821 Peptide deformylase superfamily MCR_1853 56817e303791b0998adb7e550ce7d8ca 184 SUPERFAMILY SSF56420 2 167 1.96E-61 T 14-10-2018 IPR036821 Peptide deformylase superfamily MCR_0978 d48772b62f097f384d546c57761c34d8 127 Pfam PF02472 Biopolymer transport protein ExbD/TolR 1 123 1.9E-22 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 MCR_0978 d48772b62f097f384d546c57761c34d8 127 Gene3D G3DSA:3.30.420.270 47 121 5.3E-14 T 14-10-2018 MCR_1466 97c682d1c06fe7d7aa5138469b2867c6 177 Pfam PF01613 Flavin reductase like domain 11 158 5.7E-34 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MCR_1466 97c682d1c06fe7d7aa5138469b2867c6 177 SUPERFAMILY SSF50475 7 160 2.16E-46 T 14-10-2018 MCR_1466 97c682d1c06fe7d7aa5138469b2867c6 177 Gene3D G3DSA:2.30.110.10 2 163 9.7E-45 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MCR_1466 97c682d1c06fe7d7aa5138469b2867c6 177 SMART SM00903 11 157 3.0E-53 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MCR_0871 0810450261457a91848ed62c5947d619 230 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 58 71 - T 14-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0871 0810450261457a91848ed62c5947d619 230 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 5 224 3.7E-44 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0871 0810450261457a91848ed62c5947d619 230 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 4 230 33.435 T 14-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0871 0810450261457a91848ed62c5947d619 230 Gene3D G3DSA:3.20.20.70 3 230 9.9E-77 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0871 0810450261457a91848ed62c5947d619 230 SUPERFAMILY SSF51366 4 227 7.85E-67 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MCR_0871 0810450261457a91848ed62c5947d619 230 SMART SM00934 6 226 3.1E-87 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0871 0810450261457a91848ed62c5947d619 230 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 8 226 2.0E-54 T 14-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_1589 d8544f00ec955e422ff8e8477db2e91b 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 22.014 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MCR_1589 d8544f00ec955e422ff8e8477db2e91b 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 95 7.9E-30 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MCR_1589 d8544f00ec955e422ff8e8477db2e91b 95 Gene3D G3DSA:1.10.20.60 1 93 9.5E-17 T 14-10-2018 MCR_1589 d8544f00ec955e422ff8e8477db2e91b 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 2.0E-11 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MCR_1589 d8544f00ec955e422ff8e8477db2e91b 95 SUPERFAMILY SSF141000 3 93 6.15E-23 T 14-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 MCR_1728 bdab1706c528b1aff4a25006a75eefe0 496 Gene3D G3DSA:3.30.420.150 113 290 1.6E-77 T 14-10-2018 MCR_1728 bdab1706c528b1aff4a25006a75eefe0 496 Gene3D G3DSA:3.30.420.40 10 298 1.6E-77 T 14-10-2018 MCR_1728 bdab1706c528b1aff4a25006a75eefe0 496 SUPERFAMILY SSF53067 8 128 5.62E-34 T 14-10-2018 MCR_1728 bdab1706c528b1aff4a25006a75eefe0 496 SUPERFAMILY SSF109604 308 487 1.41E-39 T 14-10-2018 MCR_1728 bdab1706c528b1aff4a25006a75eefe0 496 PIRSF PIRSF001267 1 496 3.4E-167 T 14-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 MCR_1728 bdab1706c528b1aff4a25006a75eefe0 496 Gene3D G3DSA:1.10.3210.10 306 495 3.0E-48 T 14-10-2018 MCR_1728 bdab1706c528b1aff4a25006a75eefe0 496 SUPERFAMILY SSF53067 133 303 1.04E-39 T 14-10-2018 MCR_1728 bdab1706c528b1aff4a25006a75eefe0 496 Pfam PF02541 Ppx/GppA phosphatase family 25 303 1.2E-72 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MCR_1799 1a0834b0078068871b1f845c64ec67dc 368 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 30 365 1.8E-133 T 14-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 MCR_1799 1a0834b0078068871b1f845c64ec67dc 368 Gene3D G3DSA:3.40.50.720 31 304 2.6E-139 T 14-10-2018 MCR_1799 1a0834b0078068871b1f845c64ec67dc 368 Gene3D G3DSA:3.90.25.10 221 359 2.6E-139 T 14-10-2018 MCR_1799 1a0834b0078068871b1f845c64ec67dc 368 Pfam PF16363 GDP-mannose 4,6 dehydratase 32 354 1.4E-56 T 14-10-2018 IPR016040 NAD(P)-binding domain MCR_1799 1a0834b0078068871b1f845c64ec67dc 368 SUPERFAMILY SSF51735 29 366 8.34E-92 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1533 23637fb02db96e828f7b94fba79ab2d9 349 SUPERFAMILY SSF54060 84 309 5.65E-57 T 14-10-2018 MCR_1533 23637fb02db96e828f7b94fba79ab2d9 349 Gene3D G3DSA:3.40.570.10 97 313 4.7E-49 T 14-10-2018 MCR_1533 23637fb02db96e828f7b94fba79ab2d9 349 SMART SM00477 113 302 1.3E-32 T 14-10-2018 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 MCR_1533 23637fb02db96e828f7b94fba79ab2d9 349 Pfam PF01223 DNA/RNA non-specific endonuclease 108 300 2.1E-37 T 14-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 MCR_1533 23637fb02db96e828f7b94fba79ab2d9 349 SMART SM00892 112 302 4.0E-41 T 14-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 MCR_1533 23637fb02db96e828f7b94fba79ab2d9 349 ProSitePatterns PS01070 DNA/RNA non-specific endonucleases active site. 174 182 - T 14-10-2018 IPR018524 DNA/RNA non-specific endonuclease, active site GO:0003676|GO:0016787|GO:0046872 MCR_1795 355bf1391a7298b2a660ab6c62eef787 410 Gene3D G3DSA:3.40.50.150 370 396 4.9E-18 T 14-10-2018 MCR_1795 355bf1391a7298b2a660ab6c62eef787 410 Gene3D G3DSA:3.40.50.150 28 252 5.2E-61 T 14-10-2018 MCR_1795 355bf1391a7298b2a660ab6c62eef787 410 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 385 403 - T 14-10-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 MCR_1795 355bf1391a7298b2a660ab6c62eef787 410 SUPERFAMILY SSF53335 35 403 1.36E-79 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1795 355bf1391a7298b2a660ab6c62eef787 410 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 40 403 5.3E-89 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MCR_1795 355bf1391a7298b2a660ab6c62eef787 410 Pfam PF00145 C-5 cytosine-specific DNA methylase 40 403 4.6E-82 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MCR_1795 355bf1391a7298b2a660ab6c62eef787 410 Gene3D G3DSA:3.90.120.10 275 369 4.9E-18 T 14-10-2018 MCR_1795 355bf1391a7298b2a660ab6c62eef787 410 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 37 53 1.4E-14 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MCR_1795 355bf1391a7298b2a660ab6c62eef787 410 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 188 201 1.4E-14 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MCR_1795 355bf1391a7298b2a660ab6c62eef787 410 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 142 156 1.4E-14 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MCR_1795 355bf1391a7298b2a660ab6c62eef787 410 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 103 115 - T 14-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 MCR_0427 91858f33dddfbc5e0f0dd9d9d512b655 138 SUPERFAMILY SSF117782 57 138 1.83E-15 T 14-10-2018 IPR035439 UPF0145 domain superfamily MCR_0427 91858f33dddfbc5e0f0dd9d9d512b655 138 Gene3D G3DSA:3.30.110.70 46 138 8.0E-14 T 14-10-2018 MCR_0427 91858f33dddfbc5e0f0dd9d9d512b655 138 Pfam PF01906 Putative heavy-metal-binding 57 138 5.2E-15 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 MCR_1009 daaf875776c8f043983953455664dae5 378 Pfam PF07549 SecD/SecF GG Motif 89 116 1.8E-8 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MCR_1009 daaf875776c8f043983953455664dae5 378 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 154 336 3.4E-45 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MCR_1009 daaf875776c8f043983953455664dae5 378 Gene3D G3DSA:1.20.1640.10 172 352 8.8E-13 T 14-10-2018 MCR_1009 daaf875776c8f043983953455664dae5 378 SUPERFAMILY SSF82866 131 346 8.76E-37 T 14-10-2018 MCR_1009 daaf875776c8f043983953455664dae5 378 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 67 350 27.035 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MCR_1009 daaf875776c8f043983953455664dae5 378 Pfam PF02355 Protein export membrane protein 174 346 7.0E-59 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MCR_1009 daaf875776c8f043983953455664dae5 378 PRINTS PR01755 Bacterial translocase SecF protein signature 207 221 2.4E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MCR_1009 daaf875776c8f043983953455664dae5 378 PRINTS PR01755 Bacterial translocase SecF protein signature 287 302 2.4E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MCR_1009 daaf875776c8f043983953455664dae5 378 PRINTS PR01755 Bacterial translocase SecF protein signature 94 109 2.4E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MCR_1009 daaf875776c8f043983953455664dae5 378 PRINTS PR01755 Bacterial translocase SecF protein signature 255 273 2.4E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MCR_1009 daaf875776c8f043983953455664dae5 378 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 95 339 3.5E-72 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MCR_0873 4d7156bd239e5ba4379a5192012d74a3 215 Pfam PF01914 MarC family integral membrane protein 4 211 7.8E-46 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MCR_0873 4d7156bd239e5ba4379a5192012d74a3 215 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 207 2.7E-44 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MCR_0473 74f1de237de340bd578dc9212f4b5072 238 Pfam PF01980 Uncharacterised protein family UPF0066 20 143 3.1E-38 T 14-10-2018 IPR023370 YaeB-like, N-terminal domain MCR_0473 74f1de237de340bd578dc9212f4b5072 238 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 2 148 1.1E-36 T 14-10-2018 IPR023370 YaeB-like, N-terminal domain MCR_0473 74f1de237de340bd578dc9212f4b5072 238 Gene3D G3DSA:2.40.30.70 21 151 1.5E-44 T 14-10-2018 IPR036414 YaeB, N-terminal domain superfamily MCR_0473 74f1de237de340bd578dc9212f4b5072 238 SUPERFAMILY SSF118196 1 227 3.92E-63 T 14-10-2018 IPR036413 YaeB-like superfamily MCR_1563 c3c2ea3726b097787c1badf934a0ffba 130 PIRSF PIRSF002131 1 130 8.1E-52 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MCR_1563 c3c2ea3726b097787c1badf934a0ffba 130 SUPERFAMILY SSF53137 16 130 3.14E-45 T 14-10-2018 MCR_1563 c3c2ea3726b097787c1badf934a0ffba 130 Gene3D G3DSA:3.30.420.80 1 130 1.4E-52 T 14-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 MCR_1563 c3c2ea3726b097787c1badf934a0ffba 130 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 130 32.945 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MCR_1563 c3c2ea3726b097787c1badf934a0ffba 130 Pfam PF00411 Ribosomal protein S11 19 129 4.1E-48 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MCR_1563 c3c2ea3726b097787c1badf934a0ffba 130 ProSitePatterns PS00054 Ribosomal protein S11 signature. 98 120 - T 14-10-2018 IPR018102 Ribosomal S11, conserved site MCR_1563 c3c2ea3726b097787c1badf934a0ffba 130 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 12 127 1.5E-53 T 14-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0278 16bcaac75a68098ca0ef3b2a4fd2f822 215 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 11 189 9.0E-50 T 14-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0278 16bcaac75a68098ca0ef3b2a4fd2f822 215 Pfam PF00156 Phosphoribosyl transferase domain 53 166 2.6E-15 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MCR_0278 16bcaac75a68098ca0ef3b2a4fd2f822 215 SUPERFAMILY SSF53271 6 196 2.1E-43 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MCR_0278 16bcaac75a68098ca0ef3b2a4fd2f822 215 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 215 29.117 T 14-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0278 16bcaac75a68098ca0ef3b2a4fd2f822 215 Gene3D G3DSA:3.40.50.2020 1 215 5.9E-69 T 14-10-2018 MCR_1175 8a9109bcf7ab7eb8ea7f9ff0138d4f2c 370 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 257 263 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MCR_1175 8a9109bcf7ab7eb8ea7f9ff0138d4f2c 370 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 46 347 1.7E-111 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MCR_1175 8a9109bcf7ab7eb8ea7f9ff0138d4f2c 370 Pfam PF05175 Methyltransferase small domain 185 285 1.4E-16 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MCR_1175 8a9109bcf7ab7eb8ea7f9ff0138d4f2c 370 SUPERFAMILY SSF53335 48 347 6.18E-47 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1175 8a9109bcf7ab7eb8ea7f9ff0138d4f2c 370 PIRSF PIRSF037167 30 360 1.0E-125 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MCR_1175 8a9109bcf7ab7eb8ea7f9ff0138d4f2c 370 Gene3D G3DSA:3.40.50.150 137 333 1.2E-46 T 14-10-2018 MCR_1175 8a9109bcf7ab7eb8ea7f9ff0138d4f2c 370 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 48 347 4.6E-72 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MCR_0934 30ec0422cd3ae5dd3f6c6142c9372690 378 SUPERFAMILY SSF52540 143 329 2.39E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0934 30ec0422cd3ae5dd3f6c6142c9372690 378 PIRSF PIRSF028756 78 362 2.3E-122 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 MCR_0934 30ec0422cd3ae5dd3f6c6142c9372690 378 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 112 337 4.3E-105 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related MCR_0934 30ec0422cd3ae5dd3f6c6142c9372690 378 Gene3D G3DSA:3.40.50.300 78 358 3.3E-105 T 14-10-2018 MCR_0934 30ec0422cd3ae5dd3f6c6142c9372690 378 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 111 338 2.5E-118 T 14-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 MCR_1380 c920b9860fd38cd111efdfbe060bb1e1 252 Gene3D G3DSA:2.40.160.170 29 252 1.1E-66 T 14-10-2018 MCR_1380 c920b9860fd38cd111efdfbe060bb1e1 252 SUPERFAMILY SSF56925 49 252 3.66E-5 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MCR_0251 a078c5898d4eab4687210d8ab85b8cd1 157 Hamap MF_00422 Protein translocase subunit SecE [secE]. 100 155 11.5 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MCR_0251 a078c5898d4eab4687210d8ab85b8cd1 157 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 103 156 1.5E-15 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MCR_0251 a078c5898d4eab4687210d8ab85b8cd1 157 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 106 156 7.1E-16 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MCR_0251 a078c5898d4eab4687210d8ab85b8cd1 157 PRINTS PR01650 Bacterial translocase SecE signature 99 119 1.1E-8 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MCR_0251 a078c5898d4eab4687210d8ab85b8cd1 157 PRINTS PR01650 Bacterial translocase SecE signature 123 143 1.1E-8 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MCR_0251 a078c5898d4eab4687210d8ab85b8cd1 157 PRINTS PR01650 Bacterial translocase SecE signature 78 99 1.1E-8 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MCR_0251 a078c5898d4eab4687210d8ab85b8cd1 157 PRINTS PR01650 Bacterial translocase SecE signature 143 157 1.1E-8 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MCR_0251 a078c5898d4eab4687210d8ab85b8cd1 157 Gene3D G3DSA:1.20.5.1030 100 156 2.5E-16 T 14-10-2018 IPR038379 SecE superfamily MCR_0251 a078c5898d4eab4687210d8ab85b8cd1 157 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 105 133 - T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 Pfam PF02142 MGS-like domain 16 127 1.0E-25 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 SMART SM00851 15 128 2.1E-52 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 SUPERFAMILY SSF52335 3 191 1.44E-67 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 532 44.101 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 Gene3D G3DSA:3.40.140.20 218 373 2.9E-56 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 PIRSF PIRSF000414 1 532 6.2E-217 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 SUPERFAMILY SSF53927 220 532 1.1E-128 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 6 532 4.9E-234 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 Pfam PF01808 AICARFT/IMPCHase bienzyme 133 463 4.0E-118 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 SMART SM00798 133 464 4.5E-209 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 Gene3D G3DSA:3.40.140.20 395 532 1.7E-60 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MCR_0614 8ed4884bb607dd0b305b7d5c2833d7fd 532 Gene3D G3DSA:3.40.50.1380 1 192 1.7E-79 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MCR_0291 a01610157e267895bdc74079d2d0709c 519 Pfam PF13192 Thioredoxin domain 127 197 5.5E-10 T 14-10-2018 IPR012336 Thioredoxin-like fold MCR_0291 a01610157e267895bdc74079d2d0709c 519 Gene3D G3DSA:3.50.50.60 217 508 1.1E-100 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0291 a01610157e267895bdc74079d2d0709c 519 SUPERFAMILY SSF51905 215 515 7.06E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0291 a01610157e267895bdc74079d2d0709c 519 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 2 517 1.7E-232 T 14-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 316 324 1.4E-55 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 405 421 1.4E-55 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 478 496 1.4E-55 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 249 264 1.4E-55 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 338 350 1.4E-55 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 217 239 1.4E-55 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 279 1.4E-55 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 444 465 1.4E-55 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 353 377 1.4E-55 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 357 375 7.6E-35 T 14-10-2018 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 315 333 7.6E-35 T 14-10-2018 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 442 458 7.6E-35 T 14-10-2018 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 468 490 7.6E-35 T 14-10-2018 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 218 237 7.6E-35 T 14-10-2018 MCR_0291 a01610157e267895bdc74079d2d0709c 519 SUPERFAMILY SSF52833 2 102 1.34E-21 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0291 a01610157e267895bdc74079d2d0709c 519 Gene3D G3DSA:3.40.30.80 2 201 8.3E-60 T 14-10-2018 MCR_0291 a01610157e267895bdc74079d2d0709c 519 Gene3D G3DSA:3.50.50.60 327 450 1.1E-100 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0291 a01610157e267895bdc74079d2d0709c 519 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 345 365 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MCR_0291 a01610157e267895bdc74079d2d0709c 519 PIRSF PIRSF000238 2 519 2.6E-207 T 14-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 MCR_0291 a01610157e267895bdc74079d2d0709c 519 SUPERFAMILY SSF52833 106 199 4.02E-20 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0291 a01610157e267895bdc74079d2d0709c 519 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 217 504 8.8E-41 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MCR_0192 fb59e9d7652dd11a8a2116e745ebf108 207 Gene3D G3DSA:2.30.270.10 106 173 4.4E-7 T 14-10-2018 IPR023361 DUF1285, beta-roll domain superfamily MCR_0192 fb59e9d7652dd11a8a2116e745ebf108 207 Gene3D G3DSA:3.10.540.10 7 105 1.3E-23 T 14-10-2018 MCR_0192 fb59e9d7652dd11a8a2116e745ebf108 207 Pfam PF06938 Protein of unknown function (DUF1285) 51 201 1.5E-44 T 14-10-2018 IPR010707 Protein of unknown function DUF1285 MCR_1573 8af6f1d0daa3e9970526bab3e6315db1 178 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 14-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1573 8af6f1d0daa3e9970526bab3e6315db1 178 SUPERFAMILY SSF55282 3 178 2.83E-75 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1573 8af6f1d0daa3e9970526bab3e6315db1 178 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 178 41.747 T 14-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1573 8af6f1d0daa3e9970526bab3e6315db1 178 Pfam PF00673 ribosomal L5P family C-terminus 84 177 6.0E-41 T 14-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1573 8af6f1d0daa3e9970526bab3e6315db1 178 PIRSF PIRSF002161 1 178 2.7E-64 T 14-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1573 8af6f1d0daa3e9970526bab3e6315db1 178 Pfam PF00281 Ribosomal protein L5 24 80 9.5E-29 T 14-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1573 8af6f1d0daa3e9970526bab3e6315db1 178 Gene3D G3DSA:3.30.1440.10 1 178 6.1E-77 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1489 50d4239f8d5ff0eaa8fd158290deb22e 347 Gene3D G3DSA:3.10.520.20 11 346 3.7E-92 T 14-10-2018 MCR_1489 50d4239f8d5ff0eaa8fd158290deb22e 347 SUPERFAMILY SSF143631 24 343 1.67E-82 T 14-10-2018 IPR003374 ApbE-like superfamily MCR_1489 50d4239f8d5ff0eaa8fd158290deb22e 347 Pfam PF02424 ApbE family 31 322 1.2E-73 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 MCR_1489 50d4239f8d5ff0eaa8fd158290deb22e 347 PIRSF PIRSF006268 3 344 1.5E-77 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 SUPERFAMILY SSF51230 2 90 1.44E-20 T 14-10-2018 IPR011053 Single hybrid motif MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 Gene3D G3DSA:4.10.320.10 254 297 5.7E-16 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 23 52 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 330 556 2.6E-70 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 146 175 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 SUPERFAMILY SSF52777 322 556 1.11E-73 T 14-10-2018 MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 SUPERFAMILY SSF51230 126 211 7.59E-20 T 14-10-2018 IPR011053 Single hybrid motif MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 Gene3D G3DSA:2.40.50.100 124 199 2.5E-20 T 14-10-2018 MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 Gene3D G3DSA:2.40.50.100 1 76 4.1E-19 T 14-10-2018 MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 Pfam PF00364 Biotin-requiring enzyme 2 72 3.5E-19 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 Pfam PF00364 Biotin-requiring enzyme 128 195 5.2E-19 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 SUPERFAMILY SSF47005 249 293 2.35E-11 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 Gene3D G3DSA:3.30.559.10 314 556 5.2E-80 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MCR_0893 05a52f0c0152a17b9cfdc90588b90380 556 Pfam PF02817 e3 binding domain 254 287 4.3E-14 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MCR_1367 c68073663dfa69fe086f2ac9ab780c8e 354 SUPERFAMILY SSF53822 80 271 2.89E-12 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MCR_1367 c68073663dfa69fe086f2ac9ab780c8e 354 Gene3D G3DSA:3.40.50.2300 70 316 2.5E-76 T 14-10-2018 MCR_1367 c68073663dfa69fe086f2ac9ab780c8e 354 Gene3D G3DSA:3.40.50.2300 167 334 2.5E-76 T 14-10-2018 MCR_1367 c68073663dfa69fe086f2ac9ab780c8e 354 Pfam PF04392 ABC transporter substrate binding protein 52 336 3.0E-87 T 14-10-2018 IPR007487 ABC transporter, substrate-binding protein MCR_0732 38325e6776205d18faf5e914835abbd6 513 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 425 512 7.4E-21 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MCR_0732 38325e6776205d18faf5e914835abbd6 513 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 327 419 3.1E-21 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MCR_0732 38325e6776205d18faf5e914835abbd6 513 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MCR_0732 38325e6776205d18faf5e914835abbd6 513 Gene3D G3DSA:3.40.50.1100 50 146 3.3E-125 T 14-10-2018 MCR_0732 38325e6776205d18faf5e914835abbd6 513 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 314 2.8E-71 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MCR_0732 38325e6776205d18faf5e914835abbd6 513 SUPERFAMILY SSF55021 420 512 2.98E-23 T 14-10-2018 MCR_0732 38325e6776205d18faf5e914835abbd6 513 SUPERFAMILY SSF53686 4 363 4.32E-95 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MCR_0732 38325e6776205d18faf5e914835abbd6 513 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 5 512 3.2E-206 T 14-10-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MCR_0732 38325e6776205d18faf5e914835abbd6 513 Gene3D G3DSA:3.40.1020.10 336 513 3.1E-61 T 14-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MCR_0732 38325e6776205d18faf5e914835abbd6 513 Gene3D G3DSA:3.40.50.1100 14 325 3.3E-125 T 14-10-2018 MCR_0732 38325e6776205d18faf5e914835abbd6 513 SUPERFAMILY SSF55021 334 423 1.81E-23 T 14-10-2018 MCR_1889 3d31ab13bc23ba21d511af683069ea90 412 Pfam PF16193 AAA C-terminal domain 179 245 1.2E-20 T 14-10-2018 IPR032423 AAA C-terminal domain MCR_1889 3d31ab13bc23ba21d511af683069ea90 412 Gene3D G3DSA:3.40.50.300 1 149 4.7E-39 T 14-10-2018 MCR_1889 3d31ab13bc23ba21d511af683069ea90 412 SUPERFAMILY SSF48019 230 410 1.19E-68 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MCR_1889 3d31ab13bc23ba21d511af683069ea90 412 Gene3D G3DSA:1.10.3710.10 324 412 3.6E-25 T 14-10-2018 MCR_1889 3d31ab13bc23ba21d511af683069ea90 412 Pfam PF12002 MgsA AAA+ ATPase C terminal 246 403 2.0E-64 T 14-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal MCR_1889 3d31ab13bc23ba21d511af683069ea90 412 SMART SM00382 37 151 3.8E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1889 3d31ab13bc23ba21d511af683069ea90 412 Gene3D G3DSA:1.20.272.10 219 323 5.6E-44 T 14-10-2018 MCR_1889 3d31ab13bc23ba21d511af683069ea90 412 SUPERFAMILY SSF52540 2 206 1.33E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1889 3d31ab13bc23ba21d511af683069ea90 412 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 6 122 1.7E-11 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 3.5E-64 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 3.5E-64 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 3.5E-64 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 254 272 3.5E-64 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 3.5E-64 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 237 253 3.5E-64 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 3.5E-64 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 2 281 35.738 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 Gene3D G3DSA:3.40.50.720 5 257 3.7E-103 T 14-10-2018 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 258 266 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 4 120 1.4E-39 T 14-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 SUPERFAMILY SSF53223 1 121 1.82E-39 T 14-10-2018 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 SUPERFAMILY SSF51735 127 278 2.64E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1044 ca1a67ef608f31f69798298a361738a7 283 Gene3D G3DSA:3.40.50.10860 7 275 3.7E-103 T 14-10-2018 MCR_1044 ca1a67ef608f31f69798298a361738a7 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 127 280 1.7E-62 T 14-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MCR_1007 c805494152b60ae938b51df59e2ac486 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 43 61 8.3E-12 T 14-10-2018 IPR003849 Preprotein translocase YajC MCR_1007 c805494152b60ae938b51df59e2ac486 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 23 43 8.3E-12 T 14-10-2018 IPR003849 Preprotein translocase YajC MCR_1007 c805494152b60ae938b51df59e2ac486 111 SMART SM01323 21 103 2.8E-34 T 14-10-2018 IPR003849 Preprotein translocase YajC MCR_1007 c805494152b60ae938b51df59e2ac486 111 Pfam PF02699 Preprotein translocase subunit 25 100 1.6E-25 T 14-10-2018 IPR003849 Preprotein translocase YajC MCR_1007 c805494152b60ae938b51df59e2ac486 111 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 22 103 8.0E-26 T 14-10-2018 IPR003849 Preprotein translocase YajC MCR_0037 3e40a225b2e196d5a2efb60ea04d85fb 110 Pfam PF01521 Iron-sulphur cluster biosynthesis 5 105 1.2E-17 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MCR_0037 3e40a225b2e196d5a2efb60ea04d85fb 110 Gene3D G3DSA:2.60.300.12 5 110 3.2E-32 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MCR_0037 3e40a225b2e196d5a2efb60ea04d85fb 110 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 91 108 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MCR_0037 3e40a225b2e196d5a2efb60ea04d85fb 110 SUPERFAMILY SSF89360 4 96 3.92E-29 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MCR_0037 3e40a225b2e196d5a2efb60ea04d85fb 110 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 5 109 6.3E-35 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MCR_0105 c8b8cf3b3a6ccf790387dcfd8fea6167 181 SUPERFAMILY SSF48452 2 177 1.18E-60 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0105 c8b8cf3b3a6ccf790387dcfd8fea6167 181 Pfam PF06041 Bacterial protein of unknown function (DUF924) 8 177 2.5E-56 T 14-10-2018 IPR010323 Protein of unknown function DUF924 MCR_0105 c8b8cf3b3a6ccf790387dcfd8fea6167 181 Gene3D G3DSA:1.25.40.10 81 181 3.0E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0105 c8b8cf3b3a6ccf790387dcfd8fea6167 181 Gene3D G3DSA:1.20.58.320 2 80 4.1E-25 T 14-10-2018 MCR_0279 af11a802d0f59a74706228022d52858d 323 TIGRFAM TIGR01380 glut_syn: glutathione synthase 4 313 1.1E-122 T 14-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MCR_0279 af11a802d0f59a74706228022d52858d 323 Hamap MF_00162 Glutathione synthetase [gshB]. 1 318 147.244 T 14-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MCR_0279 af11a802d0f59a74706228022d52858d 323 SUPERFAMILY SSF56059 125 314 1.02E-54 T 14-10-2018 MCR_0279 af11a802d0f59a74706228022d52858d 323 Gene3D G3DSA:3.40.50.20 9 116 4.9E-110 T 14-10-2018 MCR_0279 af11a802d0f59a74706228022d52858d 323 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 126 298 5.3E-74 T 14-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MCR_0279 af11a802d0f59a74706228022d52858d 323 Gene3D G3DSA:3.30.1490.20 139 203 4.9E-110 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MCR_0279 af11a802d0f59a74706228022d52858d 323 SUPERFAMILY SSF52440 4 124 6.62E-40 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MCR_0279 af11a802d0f59a74706228022d52858d 323 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 4 121 1.2E-38 T 14-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MCR_0279 af11a802d0f59a74706228022d52858d 323 Gene3D G3DSA:3.30.470.20 117 297 4.9E-110 T 14-10-2018 MCR_0542 a44633b26d37bc66dc821c1740227044 282 Pfam PF01148 Cytidylyltransferase family 2 258 4.5E-59 T 14-10-2018 MCR_0542 a44633b26d37bc66dc821c1740227044 282 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 218 244 - T 14-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 MCR_0330 9095a503c62c16e6c7b34c57730a8b17 295 SUPERFAMILY SSF53850 89 292 3.8E-40 T 14-10-2018 MCR_0330 9095a503c62c16e6c7b34c57730a8b17 295 Gene3D G3DSA:3.40.190.10 163 267 5.0E-68 T 14-10-2018 MCR_0330 9095a503c62c16e6c7b34c57730a8b17 295 SUPERFAMILY SSF46785 1 112 2.21E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0330 9095a503c62c16e6c7b34c57730a8b17 295 Gene3D G3DSA:3.40.190.10 93 290 5.0E-68 T 14-10-2018 MCR_0330 9095a503c62c16e6c7b34c57730a8b17 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.1E-13 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_0330 9095a503c62c16e6c7b34c57730a8b17 295 Pfam PF03466 LysR substrate binding domain 88 291 5.3E-38 T 14-10-2018 IPR005119 LysR, substrate-binding MCR_0330 9095a503c62c16e6c7b34c57730a8b17 295 Gene3D G3DSA:1.10.10.10 1 92 3.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0431 3305a9d70f1e078bff2715f82c211e3b 301 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 5 300 3.9E-119 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MCR_0431 3305a9d70f1e078bff2715f82c211e3b 301 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 6 276 1.0E-102 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MCR_0431 3305a9d70f1e078bff2715f82c211e3b 301 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 4 280 45.084 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MCR_0431 3305a9d70f1e078bff2715f82c211e3b 301 SUPERFAMILY SSF54211 5 124 3.11E-40 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_0431 3305a9d70f1e078bff2715f82c211e3b 301 SUPERFAMILY SSF54211 134 277 2.05E-48 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_0431 3305a9d70f1e078bff2715f82c211e3b 301 Gene3D G3DSA:3.30.230.20 3 127 8.6E-44 T 14-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MCR_0431 3305a9d70f1e078bff2715f82c211e3b 301 Gene3D G3DSA:3.30.1700.10 128 301 5.9E-64 T 14-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MCR_1893 c7bd99deeae994c2e5b202c91747bfd0 414 SUPERFAMILY SSF102405 86 297 2.93E-37 T 14-10-2018 MCR_1893 c7bd99deeae994c2e5b202c91747bfd0 414 Gene3D G3DSA:3.40.50.450 3 300 5.9E-90 T 14-10-2018 MCR_1893 c7bd99deeae994c2e5b202c91747bfd0 414 Pfam PF02481 DNA recombination-mediator protein A 81 288 2.0E-74 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MCR_1893 c7bd99deeae994c2e5b202c91747bfd0 414 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 84 297 1.0E-72 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MCR_1172 70115157b145c30a9435a195779ec43a 371 SUPERFAMILY SSF51717 16 209 3.92E-11 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MCR_1172 70115157b145c30a9435a195779ec43a 371 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 363 34.142 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MCR_1172 70115157b145c30a9435a195779ec43a 371 SUPERFAMILY SSF56014 265 357 2.24E-12 T 14-10-2018 MCR_1172 70115157b145c30a9435a195779ec43a 371 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 352 2.9E-125 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MCR_1172 70115157b145c30a9435a195779ec43a 371 PIRSF PIRSF004640 1 363 7.8E-144 T 14-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MCR_1172 70115157b145c30a9435a195779ec43a 371 Pfam PF04551 GcpE protein 12 353 2.6E-130 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MCR_1172 70115157b145c30a9435a195779ec43a 371 Gene3D G3DSA:3.20.20.20 1 261 3.7E-103 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MCR_1172 70115157b145c30a9435a195779ec43a 371 Gene3D G3DSA:3.30.413.10 262 362 5.7E-26 T 14-10-2018 MCR_0695 03899ce83247bd071a326669e64b5ab3 547 SUPERFAMILY SSF82689 435 532 8.89E-5 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MCR_0695 03899ce83247bd071a326669e64b5ab3 547 Pfam PF00924 Mechanosensitive ion channel 319 520 1.6E-39 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MCR_0695 03899ce83247bd071a326669e64b5ab3 547 SUPERFAMILY SSF50182 362 427 1.31E-14 T 14-10-2018 IPR010920 LSM domain superfamily MCR_0695 03899ce83247bd071a326669e64b5ab3 547 Gene3D G3DSA:2.30.30.60 378 427 6.8E-12 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MCR_0695 03899ce83247bd071a326669e64b5ab3 547 SUPERFAMILY SSF82861 278 360 1.44E-10 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MCR_0728 c96b3b1c05d557a45bd8954738e03a53 166 SUPERFAMILY SSF52788 4 152 2.22E-40 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MCR_0728 c96b3b1c05d557a45bd8954738e03a53 166 SMART SM00226 5 154 1.7E-31 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MCR_0728 c96b3b1c05d557a45bd8954738e03a53 166 Gene3D G3DSA:3.40.50.2300 5 160 4.0E-47 T 14-10-2018 MCR_0728 c96b3b1c05d557a45bd8954738e03a53 166 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 48 64 9.5E-25 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MCR_0728 c96b3b1c05d557a45bd8954738e03a53 166 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 82 97 9.5E-25 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MCR_0728 c96b3b1c05d557a45bd8954738e03a53 166 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 126 141 9.5E-25 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MCR_0728 c96b3b1c05d557a45bd8954738e03a53 166 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 7 24 9.5E-25 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MCR_0728 c96b3b1c05d557a45bd8954738e03a53 166 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 149 2.6E-31 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MCR_1250 62a2ba665d549af58a5a6f23768b9092 489 Gene3D G3DSA:3.40.1190.20 218 481 1.9E-63 T 14-10-2018 IPR029056 Ribokinase-like MCR_1250 62a2ba665d549af58a5a6f23768b9092 489 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 424 434 - T 14-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site MCR_1250 62a2ba665d549af58a5a6f23768b9092 489 Pfam PF01256 Carbohydrate kinase 238 465 1.8E-44 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MCR_1250 62a2ba665d549af58a5a6f23768b9092 489 Pfam PF03853 YjeF-related protein N-terminus 31 182 1.7E-26 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MCR_1250 62a2ba665d549af58a5a6f23768b9092 489 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 209 485 18.66 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MCR_1250 62a2ba665d549af58a5a6f23768b9092 489 Gene3D G3DSA:3.40.50.10260 12 206 3.4E-37 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 MCR_1250 62a2ba665d549af58a5a6f23768b9092 489 SUPERFAMILY SSF64153 7 210 6.67E-42 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 MCR_1250 62a2ba665d549af58a5a6f23768b9092 489 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 227 464 2.2E-47 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MCR_1250 62a2ba665d549af58a5a6f23768b9092 489 PIRSF PIRSF017184 6 483 1.8E-88 T 14-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 MCR_1250 62a2ba665d549af58a5a6f23768b9092 489 SUPERFAMILY SSF53613 226 463 6.55E-52 T 14-10-2018 IPR029056 Ribokinase-like MCR_1425 b193acd18a52b39501d9291dfa6edec3 280 Pfam PF00290 Tryptophan synthase alpha chain 9 258 7.0E-81 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MCR_1425 b193acd18a52b39501d9291dfa6edec3 280 Gene3D G3DSA:3.20.20.70 1 278 2.3E-91 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1425 b193acd18a52b39501d9291dfa6edec3 280 SUPERFAMILY SSF51366 3 258 2.51E-83 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MCR_1425 b193acd18a52b39501d9291dfa6edec3 280 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 9 258 7.0E-73 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MCR_1425 b193acd18a52b39501d9291dfa6edec3 280 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 49 62 - T 14-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MCR_1425 b193acd18a52b39501d9291dfa6edec3 280 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 15 275 32.195 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MCR_0557 a0a31f5e914f5529b949659117e00403 442 SUPERFAMILY SSF53720 2 434 1.96E-148 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MCR_0557 a0a31f5e914f5529b949659117e00403 442 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 233 244 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MCR_0557 a0a31f5e914f5529b949659117e00403 442 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 200 207 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MCR_0557 a0a31f5e914f5529b949659117e00403 442 Gene3D G3DSA:3.40.309.10 204 399 1.7E-155 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MCR_0557 a0a31f5e914f5529b949659117e00403 442 Pfam PF00171 Aldehyde dehydrogenase family 2 429 3.4E-159 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MCR_0557 a0a31f5e914f5529b949659117e00403 442 Gene3D G3DSA:3.40.605.10 2 427 1.7E-155 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MCR_0125 3f052c24c0428f6fa6233f7a02b236d3 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 12 39 4.1E-41 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MCR_0125 3f052c24c0428f6fa6233f7a02b236d3 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 158 186 4.1E-41 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MCR_0125 3f052c24c0428f6fa6233f7a02b236d3 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 107 133 4.1E-41 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MCR_0125 3f052c24c0428f6fa6233f7a02b236d3 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 89 107 4.1E-41 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MCR_0125 3f052c24c0428f6fa6233f7a02b236d3 247 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 245 15.531 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MCR_0125 3f052c24c0428f6fa6233f7a02b236d3 247 Pfam PF00902 Sec-independent protein translocase protein (TatC) 16 225 2.8E-61 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MCR_0125 3f052c24c0428f6fa6233f7a02b236d3 247 ProSitePatterns PS01218 TatC family signature. 158 177 - T 14-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site MCR_0125 3f052c24c0428f6fa6233f7a02b236d3 247 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 13 230 2.9E-61 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MCR_1203 33adf9fb3e709a279cb838df1cc3f35b 375 Gene3D G3DSA:3.90.1150.10 266 375 2.3E-44 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_1203 33adf9fb3e709a279cb838df1cc3f35b 375 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 202 221 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MCR_1203 33adf9fb3e709a279cb838df1cc3f35b 375 Pfam PF00266 Aminotransferase class-V 18 363 9.0E-55 T 14-10-2018 IPR000192 Aminotransferase class V domain MCR_1203 33adf9fb3e709a279cb838df1cc3f35b 375 Gene3D G3DSA:3.40.640.10 29 265 1.1E-87 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_1203 33adf9fb3e709a279cb838df1cc3f35b 375 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 14 374 49.214 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MCR_1203 33adf9fb3e709a279cb838df1cc3f35b 375 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 17 374 7.4E-156 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MCR_1203 33adf9fb3e709a279cb838df1cc3f35b 375 SUPERFAMILY SSF53383 14 373 1.42E-112 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_1203 33adf9fb3e709a279cb838df1cc3f35b 375 PIRSF PIRSF000525 11 375 1.1E-147 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MCR_1478 d10864959257302d73d4fc9c3466d7cb 46 SUPERFAMILY SSF57840 3 41 1.27E-13 T 14-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1478 d10864959257302d73d4fc9c3466d7cb 46 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 9 41 1.1E-7 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1478 d10864959257302d73d4fc9c3466d7cb 46 Pfam PF00444 Ribosomal protein L36 1 41 1.5E-16 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1478 d10864959257302d73d4fc9c3466d7cb 46 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 16.739 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0275 89bfa59d05bfd2c4f596623a7907b99e 1208 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1197 1.9E-241 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MCR_0275 89bfa59d05bfd2c4f596623a7907b99e 1208 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1199 17.924 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MCR_0275 89bfa59d05bfd2c4f596623a7907b99e 1208 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1190 2.5E-61 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal MCR_0275 89bfa59d05bfd2c4f596623a7907b99e 1208 SUPERFAMILY SSF57997 682 840 1.5E-6 T 14-10-2018 MCR_0275 89bfa59d05bfd2c4f596623a7907b99e 1208 Gene3D G3DSA:3.40.50.300 940 1207 2.8E-44 T 14-10-2018 MCR_0275 89bfa59d05bfd2c4f596623a7907b99e 1208 PIRSF PIRSF005719 1 512 5.0E-98 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein MCR_0275 89bfa59d05bfd2c4f596623a7907b99e 1208 PIRSF PIRSF005719 641 1205 4.0E-102 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein MCR_0275 89bfa59d05bfd2c4f596623a7907b99e 1208 SUPERFAMILY SSF52540 1 1199 2.21E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0275 89bfa59d05bfd2c4f596623a7907b99e 1208 Gene3D G3DSA:3.40.50.300 1 285 8.9E-49 T 14-10-2018 MCR_0785 05fd04a6c483ed6c1b87cf4f6e0625b1 88 Pfam PF01614 Bacterial transcriptional regulator 1 81 2.0E-6 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal MCR_0785 05fd04a6c483ed6c1b87cf4f6e0625b1 88 SUPERFAMILY SSF55781 2 85 8.5E-8 T 14-10-2018 MCR_0785 05fd04a6c483ed6c1b87cf4f6e0625b1 88 Gene3D G3DSA:3.30.450.40 1 87 1.2E-11 T 14-10-2018 IPR029016 GAF-like domain superfamily MCR_0227 020a1e99df823fa52490335e0a8921e1 157 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 3.4E-65 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MCR_0227 020a1e99df823fa52490335e0a8921e1 157 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 14-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0227 020a1e99df823fa52490335e0a8921e1 157 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 157 34.628 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MCR_0227 020a1e99df823fa52490335e0a8921e1 157 PIRSF PIRSF002122 3 157 1.9E-57 T 14-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 MCR_0227 020a1e99df823fa52490335e0a8921e1 157 SUPERFAMILY SSF47973 6 150 3.01E-56 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily MCR_0227 020a1e99df823fa52490335e0a8921e1 157 Gene3D G3DSA:1.10.455.10 2 156 2.1E-57 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily MCR_0227 020a1e99df823fa52490335e0a8921e1 157 Pfam PF00177 Ribosomal protein S7p/S5e 1 150 2.4E-63 T 14-10-2018 IPR023798 Ribosomal protein S7 domain MCR_1823 467ebddb08df73e2f6a48ca219d90830 230 SUPERFAMILY SSF56784 5 225 2.63E-52 T 14-10-2018 IPR036412 HAD-like superfamily MCR_1823 467ebddb08df73e2f6a48ca219d90830 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 2.7E-5 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_1823 467ebddb08df73e2f6a48ca219d90830 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 2.7E-5 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_1823 467ebddb08df73e2f6a48ca219d90830 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 2.7E-5 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_1823 467ebddb08df73e2f6a48ca219d90830 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 2.7E-5 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_1823 467ebddb08df73e2f6a48ca219d90830 230 Gene3D G3DSA:1.10.150.240 20 92 1.1E-52 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MCR_1823 467ebddb08df73e2f6a48ca219d90830 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 192 7.6E-34 T 14-10-2018 MCR_1823 467ebddb08df73e2f6a48ca219d90830 230 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 8 221 4.8E-49 T 14-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 MCR_1823 467ebddb08df73e2f6a48ca219d90830 230 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 97 187 4.1E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_1823 467ebddb08df73e2f6a48ca219d90830 230 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 109 190 7.5E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_1823 467ebddb08df73e2f6a48ca219d90830 230 Gene3D G3DSA:3.40.50.1000 8 199 1.1E-52 T 14-10-2018 IPR023214 HAD superfamily MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 Gene3D G3DSA:3.40.50.620 1 316 8.8E-135 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 202 220 8.9E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 233 254 8.9E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 34 45 8.9E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 70 79 8.9E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 11 479 5.7E-172 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 Pfam PF09190 DALR domain 357 419 1.7E-18 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 SUPERFAMILY SSF47323 327 479 7.45E-34 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 SMART SM00840 357 419 4.1E-20 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 Gene3D G3DSA:1.20.120.640 317 479 9.0E-42 T 14-10-2018 MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 SUPERFAMILY SSF52374 11 322 9.12E-97 T 14-10-2018 MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 24 323 3.2E-128 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 MCR_1400 bff09ed48030faa9e1a1855e44a32574 480 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 11 480 38.48 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MCR_0894 93bbd1402eac2f296750a196a6eb776e 268 SUPERFAMILY SSF47616 117 258 5.15E-27 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MCR_0894 93bbd1402eac2f296750a196a6eb776e 268 SUPERFAMILY SSF52833 39 130 9.07E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0894 93bbd1402eac2f296750a196a6eb776e 268 Pfam PF00043 Glutathione S-transferase, C-terminal domain 182 255 1.3E-4 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal MCR_0894 93bbd1402eac2f296750a196a6eb776e 268 Gene3D G3DSA:1.20.1050.10 133 254 1.9E-98 T 14-10-2018 MCR_0894 93bbd1402eac2f296750a196a6eb776e 268 Pfam PF02798 Glutathione S-transferase, N-terminal domain 46 127 7.1E-8 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MCR_0894 93bbd1402eac2f296750a196a6eb776e 268 Gene3D G3DSA:3.40.30.10 19 258 1.9E-98 T 14-10-2018 MCR_1137 de7e26d43800d980dea13f9023098b46 310 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 11 308 3.8E-124 T 14-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 MCR_1137 de7e26d43800d980dea13f9023098b46 310 Pfam PF01063 Amino-transferase class IV 36 269 8.2E-55 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MCR_1137 de7e26d43800d980dea13f9023098b46 310 SUPERFAMILY SSF56752 1 305 1.23E-103 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MCR_1137 de7e26d43800d980dea13f9023098b46 310 Gene3D G3DSA:3.20.10.10 134 297 3.3E-53 T 14-10-2018 MCR_1137 de7e26d43800d980dea13f9023098b46 310 Gene3D G3DSA:3.30.470.10 7 133 1.2E-38 T 14-10-2018 MCR_1782 0550f96b720ead86676c8dceff57c9e4 294 SUPERFAMILY SSF56235 2 266 4.25E-36 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MCR_1782 0550f96b720ead86676c8dceff57c9e4 294 Pfam PF13230 Glutamine amidotransferases class-II 1 272 2.5E-92 T 14-10-2018 IPR026869 Putative glutamine amidotransferase type 2 MCR_1782 0550f96b720ead86676c8dceff57c9e4 294 Gene3D G3DSA:3.60.20.10 1 271 2.0E-85 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MCR_0347 aca8601714b251998b511335e08e13cc 301 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 6 297 1.0E-76 T 14-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MCR_0347 aca8601714b251998b511335e08e13cc 301 SUPERFAMILY SSF54909 4 301 5.72E-79 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MCR_0347 aca8601714b251998b511335e08e13cc 301 Pfam PF04261 Dyp-type peroxidase family 6 297 5.3E-82 T 14-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MCR_1770 550dd40751800e5e62cefe591a599f79 165 SUPERFAMILY SSF75420 4 92 4.97E-21 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily MCR_1770 550dd40751800e5e62cefe591a599f79 165 Gene3D G3DSA:3.30.300.70 4 89 1.9E-20 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily MCR_1770 550dd40751800e5e62cefe591a599f79 165 Pfam PF17384 RimP C-terminal SH3 domain 95 164 6.2E-6 T 14-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MCR_1770 550dd40751800e5e62cefe591a599f79 165 SUPERFAMILY SSF74942 93 164 4.32E-9 T 14-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily MCR_1770 550dd40751800e5e62cefe591a599f79 165 Pfam PF02576 RimP N-terminal domain 13 92 4.0E-22 T 14-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MCR_1770 550dd40751800e5e62cefe591a599f79 165 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 8 165 22.281 T 14-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 MCR_0138 5e02702c67d3dc36624b5dea8e5c5acd 231 SUPERFAMILY SSF52833 82 222 4.57E-34 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0138 5e02702c67d3dc36624b5dea8e5c5acd 231 Pfam PF02630 SCO1/SenC 84 214 1.4E-23 T 14-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_0138 5e02702c67d3dc36624b5dea8e5c5acd 231 Gene3D G3DSA:3.40.30.10 73 230 6.2E-39 T 14-10-2018 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 106 216 1.8E-22 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 SMART SM00846 105 265 1.4E-54 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 Gene3D G3DSA:3.40.50.720 107 441 2.9E-113 T 14-10-2018 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 SUPERFAMILY SSF51735 105 288 1.29E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 SUPERFAMILY SSF55347 265 429 2.71E-51 T 14-10-2018 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 224 237 9.3E-20 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 286 302 9.3E-20 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 342 359 9.3E-20 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 259 277 9.3E-20 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 263 270 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 Gene3D G3DSA:3.30.360.10 264 430 2.9E-113 T 14-10-2018 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 270 428 9.6E-47 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1222 4600bcc30a539b8a421004bf43ca4834 447 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 107 440 3.0E-111 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 SUPERFAMILY SSF89000 398 447 2.2E-13 T 14-10-2018 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 Pfam PF00682 HMGL-like 39 319 5.2E-74 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 14 543 4.9E-222 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 SMART SM00917 432 570 2.9E-12 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 10 570 49.232 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 Pfam PF08502 LeuA allosteric (dimerisation) domain 433 567 5.2E-11 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 46 62 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 SUPERFAMILY SSF110921 449 566 4.05E-18 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 Gene3D G3DSA:3.30.160.270 387 569 6.5E-40 T 14-10-2018 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 SUPERFAMILY SSF51569 28 336 3.3E-100 T 14-10-2018 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 249 262 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MCR_1200 30c64a32316f6bf5df0645db7248fdf0 570 Gene3D G3DSA:3.20.20.70 20 386 8.3E-152 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0667 69a427a92ebe46c189ef1090f4b196dd 224 Gene3D G3DSA:3.40.50.1000 4 220 1.1E-63 T 14-10-2018 IPR023214 HAD superfamily MCR_0667 69a427a92ebe46c189ef1090f4b196dd 224 SUPERFAMILY SSF56784 3 217 3.56E-32 T 14-10-2018 IPR036412 HAD-like superfamily MCR_0667 69a427a92ebe46c189ef1090f4b196dd 224 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 195 2.3E-20 T 14-10-2018 MCR_0667 69a427a92ebe46c189ef1090f4b196dd 224 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 4 206 6.1E-37 T 14-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like MCR_0667 69a427a92ebe46c189ef1090f4b196dd 224 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 193 2.0E-34 T 14-10-2018 MCR_0667 69a427a92ebe46c189ef1090f4b196dd 224 Gene3D G3DSA:1.20.1440.100 16 89 1.1E-63 T 14-10-2018 MCR_0066 8fef41901d1c6a64d6283f2a28e1356e 126 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 10 123 5.6E-27 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0066 8fef41901d1c6a64d6283f2a28e1356e 126 PIRSF PIRSF000178 1 125 4.7E-22 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0066 8fef41901d1c6a64d6283f2a28e1356e 126 Gene3D G3DSA:1.20.1300.10 1 125 6.4E-28 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0066 8fef41901d1c6a64d6283f2a28e1356e 126 SUPERFAMILY SSF81343 3 124 5.67E-23 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0066 8fef41901d1c6a64d6283f2a28e1356e 126 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 3 118 6.8E-21 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0708 b130122632b777a47454027053b44a99 223 Gene3D G3DSA:3.40.50.12280 21 192 6.0E-70 T 14-10-2018 MCR_0708 b130122632b777a47454027053b44a99 223 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 146 162 - T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0708 b130122632b777a47454027053b44a99 223 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 45 180 8.9E-68 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0708 b130122632b777a47454027053b44a99 223 SUPERFAMILY SSF56770 42 183 2.88E-64 T 14-10-2018 MCR_0708 b130122632b777a47454027053b44a99 223 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 88 172 1.4E-21 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0708 b130122632b777a47454027053b44a99 223 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 25 179 42.163 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_1142 cd1881449425e48061559b084e9d483f 106 SUPERFAMILY SSF69721 6 106 4.05E-26 T 14-10-2018 IPR025526 DsrC-like domain superfamily MCR_1142 cd1881449425e48061559b084e9d483f 106 Pfam PF04358 DsrC like protein 6 106 1.3E-28 T 14-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE MCR_1142 cd1881449425e48061559b084e9d483f 106 Gene3D G3DSA:1.10.10.370 35 106 6.6E-17 T 14-10-2018 MCR_1142 cd1881449425e48061559b084e9d483f 106 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 6 106 2.0E-24 T 14-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE MCR_1142 cd1881449425e48061559b084e9d483f 106 Gene3D G3DSA:3.30.1420.10 6 32 1.0E-5 T 14-10-2018 MCR_1142 cd1881449425e48061559b084e9d483f 106 PIRSF PIRSF006223 2 106 1.0E-20 T 14-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE MCR_1738 df16f0a3db2d7ff81cdc91c07b2a32cb 108 Pfam PF04273 Putative phosphatase (DUF442) 6 100 6.5E-19 T 14-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 MCR_1738 df16f0a3db2d7ff81cdc91c07b2a32cb 108 Gene3D G3DSA:3.90.190.10 1 106 8.6E-26 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like MCR_1278 5bb095f0556853009fd1ef0b44684ea5 106 SUPERFAMILY SSF160191 1 103 3.14E-24 T 14-10-2018 IPR038068 YcgL-like superfamily MCR_1278 5bb095f0556853009fd1ef0b44684ea5 106 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 1 87 1.0E-26 T 14-10-2018 IPR027354 YcgL domain MCR_1278 5bb095f0556853009fd1ef0b44684ea5 106 Hamap MF_01866 Protein YcgL [ycgL]. 1 98 20.421 T 14-10-2018 IPR027354 YcgL domain MCR_1278 5bb095f0556853009fd1ef0b44684ea5 106 Gene3D G3DSA:3.10.510.20 1 84 6.6E-23 T 14-10-2018 IPR038068 YcgL-like superfamily MCR_1278 5bb095f0556853009fd1ef0b44684ea5 106 Pfam PF05166 YcgL domain 3 85 4.3E-27 T 14-10-2018 IPR027354 YcgL domain MCR_0253 b4e15833ff7bdd479660effe7b0ef708 143 SUPERFAMILY SSF54747 3 72 1.57E-29 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily MCR_0253 b4e15833ff7bdd479660effe7b0ef708 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 4.7E-64 T 14-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0253 b4e15833ff7bdd479660effe7b0ef708 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 14-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0253 b4e15833ff7bdd479660effe7b0ef708 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 1.3E-24 T 14-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MCR_0253 b4e15833ff7bdd479660effe7b0ef708 143 Gene3D G3DSA:3.30.1550.10 2 72 1.3E-34 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily MCR_0253 b4e15833ff7bdd479660effe7b0ef708 143 SUPERFAMILY SSF46906 68 141 3.92E-25 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily MCR_0253 b4e15833ff7bdd479660effe7b0ef708 143 Gene3D G3DSA:1.10.10.250 73 141 2.6E-26 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily MCR_0253 b4e15833ff7bdd479660effe7b0ef708 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 9.0E-13 T 14-10-2018 MCR_0253 b4e15833ff7bdd479660effe7b0ef708 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.376 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MCR_0253 b4e15833ff7bdd479660effe7b0ef708 143 SMART SM00649 9 141 6.6E-82 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MCR_0253 b4e15833ff7bdd479660effe7b0ef708 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 3.2E-29 T 14-10-2018 IPR020784 Ribosomal protein L11, N-terminal MCR_1890 793cf623a3efb3ba1c163c1709c46830 364 Pfam PF00925 GTP cyclohydrolase II 211 362 9.7E-29 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MCR_1890 793cf623a3efb3ba1c163c1709c46830 364 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 37.408 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_1890 793cf623a3efb3ba1c163c1709c46830 364 PIRSF PIRSF001259 1 363 1.2E-114 T 14-10-2018 MCR_1890 793cf623a3efb3ba1c163c1709c46830 364 Gene3D G3DSA:3.90.870.10 1 206 3.3E-86 T 14-10-2018 MCR_1890 793cf623a3efb3ba1c163c1709c46830 364 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 198 1.9E-82 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_1890 793cf623a3efb3ba1c163c1709c46830 364 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 4 199 8.9E-74 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_1890 793cf623a3efb3ba1c163c1709c46830 364 SUPERFAMILY SSF142695 205 362 5.23E-34 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MCR_1890 793cf623a3efb3ba1c163c1709c46830 364 SUPERFAMILY SSF55821 2 202 4.58E-85 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MCR_0973 56b4de3cdcd821cad4268ec7e0de9e29 392 Pfam PF12698 ABC-2 family transporter protein 28 371 1.3E-34 T 14-10-2018 MCR_1031 032ff7f7cfb60102683832674cb42bf8 281 PIRSF PIRSF000903 9 280 6.0E-91 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MCR_1031 032ff7f7cfb60102683832674cb42bf8 281 Gene3D G3DSA:3.60.21.10 10 280 1.8E-58 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like MCR_1031 032ff7f7cfb60102683832674cb42bf8 281 Pfam PF00149 Calcineurin-like phosphoesterase 13 169 1.3E-11 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MCR_1031 032ff7f7cfb60102683832674cb42bf8 281 SUPERFAMILY SSF56300 11 265 3.45E-40 T 14-10-2018 MCR_1031 032ff7f7cfb60102683832674cb42bf8 281 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 11 271 3.7E-75 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 Pfam PF00005 ABC transporter 22 191 2.3E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 551 9.8E-291 T 14-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 Pfam PF00005 ABC transporter 340 473 4.9E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 Pfam PF12848 ABC transporter 230 305 7.9E-12 T 14-10-2018 IPR032781 ABC-transporter extension domain MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 Gene3D G3DSA:3.40.50.300 1 285 2.4E-86 T 14-10-2018 MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 Gene3D G3DSA:3.40.50.300 286 551 3.5E-72 T 14-10-2018 MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 SUPERFAMILY SSF52540 9 244 6.52E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 SUPERFAMILY SSF52540 301 532 3.7E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 SMART SM00382 348 522 9.6E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 SMART SM00382 31 232 1.8E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1667 80d307a96e0125c3e06ce26b6336a8c3 553 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0185 702c4b4ca1f0d2959ed5de3a6a93218e 290 PIRSF PIRSF010376 1 288 2.5E-72 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MCR_0185 702c4b4ca1f0d2959ed5de3a6a93218e 290 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 4 261 8.9E-60 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MCR_0185 702c4b4ca1f0d2959ed5de3a6a93218e 290 Gene3D G3DSA:3.30.70.890 167 289 3.9E-14 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MCR_0185 702c4b4ca1f0d2959ed5de3a6a93218e 290 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 280 28.683 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MCR_0185 702c4b4ca1f0d2959ed5de3a6a93218e 290 Gene3D G3DSA:3.30.230.10 1 166 7.7E-50 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MCR_0185 702c4b4ca1f0d2959ed5de3a6a93218e 290 SUPERFAMILY SSF55060 167 265 5.28E-15 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MCR_0185 702c4b4ca1f0d2959ed5de3a6a93218e 290 Pfam PF00288 GHMP kinases N terminal domain 91 145 8.9E-9 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MCR_0185 702c4b4ca1f0d2959ed5de3a6a93218e 290 SUPERFAMILY SSF54211 2 165 2.5E-38 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1642 5510befee6262995cc37ef0eae8f8445 318 Gene3D G3DSA:3.30.930.10 2 214 3.3E-112 T 14-10-2018 MCR_1642 5510befee6262995cc37ef0eae8f8445 318 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 8 297 1.1E-159 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1642 5510befee6262995cc37ef0eae8f8445 318 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 61 76 8.3E-70 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1642 5510befee6262995cc37ef0eae8f8445 318 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 82 102 8.3E-70 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1642 5510befee6262995cc37ef0eae8f8445 318 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 113 137 8.3E-70 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1642 5510befee6262995cc37ef0eae8f8445 318 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 139 159 8.3E-70 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1642 5510befee6262995cc37ef0eae8f8445 318 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 251 267 8.3E-70 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1642 5510befee6262995cc37ef0eae8f8445 318 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 162 177 8.3E-70 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1642 5510befee6262995cc37ef0eae8f8445 318 Gene3D G3DSA:1.20.58.180 215 296 4.2E-32 T 14-10-2018 MCR_1642 5510befee6262995cc37ef0eae8f8445 318 SUPERFAMILY SSF55681 8 290 1.16E-132 T 14-10-2018 MCR_1642 5510befee6262995cc37ef0eae8f8445 318 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 7 291 60.876 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1642 5510befee6262995cc37ef0eae8f8445 318 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 9 289 5.4E-151 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_0351 248f99c2a10451e1e467142eb34e63ac 90 Pfam PF01192 RNA polymerase Rpb6 8 59 1.4E-16 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MCR_0351 248f99c2a10451e1e467142eb34e63ac 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 3.4E-21 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0351 248f99c2a10451e1e467142eb34e63ac 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 17.275 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0351 248f99c2a10451e1e467142eb34e63ac 90 Gene3D G3DSA:3.90.940.10 1 84 8.5E-26 T 14-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MCR_0351 248f99c2a10451e1e467142eb34e63ac 90 SMART SM01409 8 61 9.8E-17 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MCR_0351 248f99c2a10451e1e467142eb34e63ac 90 SUPERFAMILY SSF63562 1 71 3.14E-24 T 14-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MCR_1459 4e21b53d05a7a52cd4bd4c82e0f94059 410 Pfam PF03116 NQR2, RnfD, RnfE family 43 396 6.1E-109 T 14-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 MCR_1459 4e21b53d05a7a52cd4bd4c82e0f94059 410 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 3 403 36.615 T 14-10-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0010181|GO:0016021|GO:0016655|GO:0022904 MCR_1459 4e21b53d05a7a52cd4bd4c82e0f94059 410 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 5 398 1.8E-165 T 14-10-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0010181|GO:0016021|GO:0016655|GO:0022904 MCR_1459 4e21b53d05a7a52cd4bd4c82e0f94059 410 PIRSF PIRSF016055 2 405 1.2E-192 T 14-10-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0010181|GO:0016021|GO:0016655|GO:0022904 MCR_1559 3c5f2dd0c2941f91f2f144b389ce117f 188 SUPERFAMILY SSF55821 2 186 6.71E-24 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MCR_1559 3c5f2dd0c2941f91f2f144b389ce117f 188 Pfam PF01300 Telomere recombination 22 186 2.7E-13 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 MCR_1559 3c5f2dd0c2941f91f2f144b389ce117f 188 Gene3D G3DSA:3.90.870.10 1 188 2.0E-25 T 14-10-2018 MCR_1571 1c01d4f62a098cda955eeb0bc923614d 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1571 1c01d4f62a098cda955eeb0bc923614d 132 Pfam PF00410 Ribosomal protein S8 5 131 2.1E-44 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1571 1c01d4f62a098cda955eeb0bc923614d 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 29.215 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1571 1c01d4f62a098cda955eeb0bc923614d 132 Gene3D G3DSA:3.30.1370.30 2 74 5.4E-25 T 14-10-2018 MCR_1571 1c01d4f62a098cda955eeb0bc923614d 132 Gene3D G3DSA:3.30.1490.10 75 131 3.4E-21 T 14-10-2018 MCR_1571 1c01d4f62a098cda955eeb0bc923614d 132 SUPERFAMILY SSF56047 2 131 6.67E-40 T 14-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0803 5321f1f1d84cac706765502da4eaf876 617 Gene3D G3DSA:3.40.50.720 401 562 3.7E-30 T 14-10-2018 MCR_0803 5321f1f1d84cac706765502da4eaf876 617 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 18 288 1.1E-76 T 14-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 MCR_0803 5321f1f1d84cac706765502da4eaf876 617 Pfam PF00999 Sodium/hydrogen exchanger family 15 376 3.1E-64 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MCR_0803 5321f1f1d84cac706765502da4eaf876 617 SUPERFAMILY SSF51735 405 531 1.97E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0803 5321f1f1d84cac706765502da4eaf876 617 Pfam PF02254 TrkA-N domain 406 520 4.2E-22 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MCR_0803 5321f1f1d84cac706765502da4eaf876 617 Gene3D G3DSA:1.20.1530.20 6 390 1.5E-74 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily MCR_1542 f0306575a6e7dda501da4530344e3087 70 SMART SM00357 6 70 1.5E-25 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 MCR_1542 f0306575a6e7dda501da4530344e3087 70 Pfam PF00313 'Cold-shock' DNA-binding domain 6 69 8.0E-28 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MCR_1542 f0306575a6e7dda501da4530344e3087 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 14-10-2018 IPR019844 Cold-shock conserved site MCR_1542 f0306575a6e7dda501da4530344e3087 70 PIRSF PIRSF002599 1 70 1.6E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 MCR_1542 f0306575a6e7dda501da4530344e3087 70 PRINTS PR00050 Cold shock protein signature 43 61 2.9E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MCR_1542 f0306575a6e7dda501da4530344e3087 70 PRINTS PR00050 Cold shock protein signature 7 22 2.9E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MCR_1542 f0306575a6e7dda501da4530344e3087 70 PRINTS PR00050 Cold shock protein signature 28 37 2.9E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MCR_1542 f0306575a6e7dda501da4530344e3087 70 Gene3D G3DSA:2.40.50.140 1 68 2.4E-28 T 14-10-2018 MCR_1542 f0306575a6e7dda501da4530344e3087 70 SUPERFAMILY SSF50249 3 68 6.12E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 279 288 2.5E-21 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 291 314 2.5E-21 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 157 168 2.5E-21 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 71 90 2.5E-21 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 Gene3D G3DSA:3.40.50.1370 32 321 6.8E-88 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 PRINTS PR00101 Aspartate carbamoyltransferase signature 156 173 1.0E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 PRINTS PR00101 Aspartate carbamoyltransferase signature 283 288 1.0E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 PRINTS PR00101 Aspartate carbamoyltransferase signature 307 321 1.0E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 PRINTS PR00101 Aspartate carbamoyltransferase signature 242 251 1.0E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 PRINTS PR00101 Aspartate carbamoyltransferase signature 61 83 1.0E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 PRINTS PR00101 Aspartate carbamoyltransferase signature 99 108 1.0E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 178 324 6.2E-27 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 26 326 1.6E-88 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 25 328 39.987 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 26 169 1.2E-38 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 Gene3D G3DSA:3.40.50.1370 157 305 6.8E-88 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 71 78 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MCR_0404 06cee85d2ea1151380b8aaba1d7d154a 339 SUPERFAMILY SSF53671 25 327 1.09E-92 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MCR_1164 a303bffce7025fd55cc730be6578cb85 426 Pfam PF02684 Lipid-A-disaccharide synthetase 9 394 5.4E-98 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 MCR_1164 a303bffce7025fd55cc730be6578cb85 426 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 6 409 32.826 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 MCR_1164 a303bffce7025fd55cc730be6578cb85 426 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 1 400 5.4E-97 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 MCR_1164 a303bffce7025fd55cc730be6578cb85 426 SUPERFAMILY SSF53756 9 408 7.43E-18 T 14-10-2018 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 251 264 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site MCR_1484 7ad409993dcf022edca0509242ef57ce 435 SUPERFAMILY SSF50621 280 434 1.95E-47 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 213 226 1.7E-26 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 81 99 1.7E-26 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 101 113 1.7E-26 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 293 312 1.7E-26 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 391 404 1.7E-26 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 SUPERFAMILY SSF51419 50 305 6.15E-81 T 14-10-2018 IPR029066 PLP-binding barrel MCR_1484 7ad409993dcf022edca0509242ef57ce 435 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 32 433 1.4E-153 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 61 303 1.7E-69 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 304 391 2.0E-21 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 81 99 - T 14-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site MCR_1484 7ad409993dcf022edca0509242ef57ce 435 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 39 434 39.968 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 Gene3D G3DSA:3.20.20.10 58 298 2.0E-141 T 14-10-2018 IPR029066 PLP-binding barrel MCR_1484 7ad409993dcf022edca0509242ef57ce 435 PRINTS PR01181 Diaminopimelate decarboxylase signature 187 196 1.3E-27 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 PRINTS PR01181 Diaminopimelate decarboxylase signature 321 339 1.3E-27 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 PRINTS PR01181 Diaminopimelate decarboxylase signature 401 423 1.3E-27 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 PRINTS PR01181 Diaminopimelate decarboxylase signature 99 116 1.3E-27 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_1484 7ad409993dcf022edca0509242ef57ce 435 Gene3D G3DSA:2.40.37.10 38 430 2.0E-141 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MCR_0734 6f85abf3c4f8ccbed03e25974ac867d2 504 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 57 500 6.1E-174 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MCR_0734 6f85abf3c4f8ccbed03e25974ac867d2 504 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 57 500 2.4E-101 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MCR_0734 6f85abf3c4f8ccbed03e25974ac867d2 504 Gene3D G3DSA:3.40.50.12160 57 183 5.0E-28 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily MCR_0734 6f85abf3c4f8ccbed03e25974ac867d2 504 Gene3D G3DSA:2.40.50.140 440 504 3.0E-17 T 14-10-2018 MCR_0734 6f85abf3c4f8ccbed03e25974ac867d2 504 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 196 216 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MCR_0734 6f85abf3c4f8ccbed03e25974ac867d2 504 SMART SM00729 192 425 6.0E-45 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MCR_0734 6f85abf3c4f8ccbed03e25974ac867d2 504 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 56 503 58.437 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MCR_0734 6f85abf3c4f8ccbed03e25974ac867d2 504 Gene3D G3DSA:3.80.30.20 190 439 1.5E-66 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MCR_0734 6f85abf3c4f8ccbed03e25974ac867d2 504 Pfam PF00919 Uncharacterized protein family UPF0004 57 149 1.1E-19 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MCR_0734 6f85abf3c4f8ccbed03e25974ac867d2 504 SUPERFAMILY SSF102114 172 430 7.85E-47 T 14-10-2018 MCR_0734 6f85abf3c4f8ccbed03e25974ac867d2 504 Pfam PF04055 Radical SAM superfamily 197 383 4.5E-25 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MCR_0739 ad53054ce7fd9a500520a5428865a3f4 954 Pfam PF00593 TonB dependent receptor 372 952 4.1E-24 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MCR_0739 ad53054ce7fd9a500520a5428865a3f4 954 Gene3D G3DSA:2.170.130.10 73 200 2.0E-30 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MCR_0739 ad53054ce7fd9a500520a5428865a3f4 954 SUPERFAMILY SSF56935 57 954 4.26E-48 T 14-10-2018 MCR_0212 d11b295029f40459597670b4bd6c705d 434 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 274 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MCR_0212 d11b295029f40459597670b4bd6c705d 434 SUPERFAMILY SSF53383 6 427 2.99E-125 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0212 d11b295029f40459597670b4bd6c705d 434 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 7 430 100.201 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MCR_0212 d11b295029f40459597670b4bd6c705d 434 Gene3D G3DSA:3.40.640.10 73 321 8.5E-169 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_0212 d11b295029f40459597670b4bd6c705d 434 Pfam PF00202 Aminotransferase class-III 36 401 2.2E-75 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MCR_0212 d11b295029f40459597670b4bd6c705d 434 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 8 428 3.0E-183 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MCR_0212 d11b295029f40459597670b4bd6c705d 434 Gene3D G3DSA:3.90.1150.10 12 422 8.5E-169 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 Pfam PF04851 Type III restriction enzyme, res subunit 183 332 6.4E-10 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 SMART SM00487 162 357 2.3E-14 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 Hamap MF_01821 RNA polymerase-associated protein RapA [rapA]. 19 967 25.024 T 14-10-2018 IPR023949 RNA polymerase-associated protein RapA GO:0006355 MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 SMART SM00490 512 595 1.6E-12 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 Gene3D G3DSA:2.30.30.140 19 71 3.2E-20 T 14-10-2018 MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 SUPERFAMILY SSF52540 287 635 7.8E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 Pfam PF12137 RNA polymerase recycling family C-terminal 599 966 1.4E-115 T 14-10-2018 IPR022737 RNA polymerase recycling, bacterial, C-terminal GO:0016817 MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 Gene3D G3DSA:3.30.360.80 711 787 1.4E-19 T 14-10-2018 MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 SUPERFAMILY SSF52540 166 359 1.32E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 Gene3D G3DSA:3.40.50.300 451 627 3.0E-36 T 14-10-2018 MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 Gene3D G3DSA:3.40.50.10810 162 438 3.5E-78 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily MCR_1528 3a53cd0b44b8aae52dfd154ea8d8ee22 970 Pfam PF00271 Helicase conserved C-terminal domain 484 595 2.4E-13 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_1116 2a3a117f58ebcbf54c16658ac203f5be 320 Pfam PF01476 LysM domain 71 113 3.2E-12 T 14-10-2018 IPR018392 LysM domain MCR_1116 2a3a117f58ebcbf54c16658ac203f5be 320 SUPERFAMILY SSF51261 71 319 9.42E-23 T 14-10-2018 IPR011055 Duplicated hybrid motif MCR_1116 2a3a117f58ebcbf54c16658ac203f5be 320 Gene3D G3DSA:2.70.70.10 197 320 5.7E-20 T 14-10-2018 IPR011055 Duplicated hybrid motif MCR_1116 2a3a117f58ebcbf54c16658ac203f5be 320 Pfam PF01551 Peptidase family M23 224 315 3.9E-16 T 14-10-2018 IPR016047 Peptidase M23 MCR_1116 2a3a117f58ebcbf54c16658ac203f5be 320 SMART SM00257 70 114 9.2E-10 T 14-10-2018 IPR018392 LysM domain MCR_1116 2a3a117f58ebcbf54c16658ac203f5be 320 Gene3D G3DSA:3.10.350.10 60 120 8.6E-13 T 14-10-2018 IPR036779 LysM domain superfamily MCR_1151 37f420bde23d47b66a7894489a0c5c15 76 SUPERFAMILY SSF116842 3 65 4.58E-6 T 14-10-2018 MCR_1151 37f420bde23d47b66a7894489a0c5c15 76 Pfam PF02609 Exonuclease VII small subunit 9 60 2.4E-6 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 Pfam PF01189 16S rRNA methyltransferase RsmB/F 256 443 1.7E-56 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 Gene3D G3DSA:3.40.50.150 145 445 1.1E-67 T 14-10-2018 MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 20 446 2.3E-98 T 14-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 377 393 1.8E-24 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 327 339 1.8E-24 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 428 445 1.8E-24 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 261 271 1.8E-24 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 227 241 1.8E-24 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 SUPERFAMILY SSF53335 145 445 2.71E-59 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 Gene3D G3DSA:1.10.940.10 10 144 3.0E-29 T 14-10-2018 IPR035926 NusB-like superfamily MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 SUPERFAMILY SSF48013 16 151 3.27E-23 T 14-10-2018 IPR035926 NusB-like superfamily MCR_1896 b98f497aa66c034f43a0987dfb27a637 448 Pfam PF01029 NusB family 23 131 5.8E-16 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MCR_1711 1045f07edc5e7d9b5c1c64ac3b972918 260 PIRSF PIRSF005426 3 260 1.4E-63 T 14-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 MCR_1711 1045f07edc5e7d9b5c1c64ac3b972918 260 SUPERFAMILY SSF55469 6 259 4.84E-58 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MCR_1711 1045f07edc5e7d9b5c1c64ac3b972918 260 Pfam PF00881 Nitroreductase family 13 178 9.1E-18 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MCR_1711 1045f07edc5e7d9b5c1c64ac3b972918 260 Gene3D G3DSA:3.40.109.10 5 260 8.5E-57 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MCR_1829 9853488fa4d163e0424cbf7505d76ddd 167 Gene3D G3DSA:1.10.60.30 20 99 8.4E-13 T 14-10-2018 MCR_1829 9853488fa4d163e0424cbf7505d76ddd 167 Pfam PF04751 Protein of unknown function (DUF615) 10 136 3.2E-25 T 14-10-2018 IPR006839 Ribosome-associated, YjgA MCR_1829 9853488fa4d163e0424cbf7505d76ddd 167 SUPERFAMILY SSF158710 21 164 1.44E-25 T 14-10-2018 IPR023153 PSPTO4464-like domain superfamily MCR_0435 a1256c89df59a47b14978c750c2d36e9 105 Gene3D G3DSA:3.30.110.60 6 102 8.0E-27 T 14-10-2018 IPR035920 YhbY-like superfamily MCR_0435 a1256c89df59a47b14978c750c2d36e9 105 SMART SM01103 7 88 1.2E-31 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MCR_0435 a1256c89df59a47b14978c750c2d36e9 105 SUPERFAMILY SSF75471 10 98 2.35E-24 T 14-10-2018 IPR035920 YhbY-like superfamily MCR_0435 a1256c89df59a47b14978c750c2d36e9 105 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 13 88 7.0E-20 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MCR_0435 a1256c89df59a47b14978c750c2d36e9 105 Pfam PF01985 CRS1 / YhbY (CRM) domain 10 88 2.4E-18 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MCR_1232 5eafdd24c4e4c039af87824f11ccd3f4 717 SUPERFAMILY SSF53474 424 703 2.95E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_1232 5eafdd24c4e4c039af87824f11ccd3f4 717 Gene3D G3DSA:3.40.50.1820 423 703 2.7E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0578 a18fcc2cfe5401ab50e5448392c91722 222 Pfam PF00551 Formyl transferase 7 187 2.4E-50 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MCR_0578 a18fcc2cfe5401ab50e5448392c91722 222 Gene3D G3DSA:3.40.50.170 1 209 4.8E-67 T 14-10-2018 MCR_0578 a18fcc2cfe5401ab50e5448392c91722 222 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 7 195 27.004 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MCR_0578 a18fcc2cfe5401ab50e5448392c91722 222 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 7 197 2.4E-55 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MCR_0578 a18fcc2cfe5401ab50e5448392c91722 222 SUPERFAMILY SSF53328 6 194 1.11E-53 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 Gene3D G3DSA:2.70.210.12 1 158 6.0E-56 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 Gene3D G3DSA:3.40.50.300 159 338 3.9E-51 T 14-10-2018 MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 14-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 3.4E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 3.4E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.4E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.4E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 1.1E-141 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 Pfam PF01018 GTP1/OBG 4 158 8.2E-56 T 14-10-2018 IPR006169 GTP1/OBG domain MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 SUPERFAMILY SSF82051 3 158 2.09E-54 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 SUPERFAMILY SSF52540 151 336 8.82E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 Pfam PF01926 50S ribosome-binding GTPase 161 284 5.7E-23 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 Hamap MF_01454 GTPase Obg [obg]. 2 333 47.18 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MCR_1220 f01e9a664d959572c955fe62e8ab2f82 404 PIRSF PIRSF002401 1 380 1.1E-135 T 14-10-2018 IPR035101 GTP-binding protein, Obg-type MCR_1316 ec9dffbf250765747fe810ff4e170436 126 Hamap MF_00599 Cell division protein FtsB [ftsB]. 12 97 21.456 T 14-10-2018 IPR023081 Cell division protein FtsB MCR_1316 ec9dffbf250765747fe810ff4e170436 126 Pfam PF04977 Septum formation initiator 18 96 4.8E-19 T 14-10-2018 IPR007060 Septum formation initiator FtsL/DivIC MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 Pfam PF00308 Bacterial dnaA protein 128 344 8.2E-58 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 ProSitePatterns PS01008 DnaA protein signature. 424 443 - T 14-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 SUPERFAMILY SSF48295 363 464 1.05E-33 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 Gene3D G3DSA:1.10.8.60 296 368 2.1E-14 T 14-10-2018 MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 Gene3D G3DSA:3.40.50.300 126 293 2.0E-35 T 14-10-2018 MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 SMART SM00382 160 296 6.5E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 SUPERFAMILY SSF52540 129 341 4.53E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 261 288 8.6E-29 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 161 181 8.6E-29 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 424 443 8.6E-29 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 SMART SM00760 374 443 3.1E-38 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 20 465 24.194 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 23 463 5.5E-122 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 376 443 2.9E-30 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 Gene3D G3DSA:1.10.1750.10 373 465 6.8E-34 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 Gene3D G3DSA:3.30.300.180 20 122 5.3E-18 T 14-10-2018 IPR038454 DnaA, N-terminal domain superfamily MCR_0002 debbfa6a43ba91d8d6fac02e3a15794e 467 Pfam PF11638 DnaA N-terminal domain 21 81 1.5E-9 T 14-10-2018 IPR024633 DnaA N-terminal domain MCR_1564 59c716d95910c57b57644a6acf4dbe7e 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 14-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1564 59c716d95910c57b57644a6acf4dbe7e 118 PIRSF PIRSF002134 1 118 2.2E-42 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1564 59c716d95910c57b57644a6acf4dbe7e 118 Gene3D G3DSA:1.10.8.50 1 71 4.7E-27 T 14-10-2018 MCR_1564 59c716d95910c57b57644a6acf4dbe7e 118 Gene3D G3DSA:4.10.910.10 72 118 2.8E-26 T 14-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1564 59c716d95910c57b57644a6acf4dbe7e 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.9E-53 T 14-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1564 59c716d95910c57b57644a6acf4dbe7e 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 8.2E-32 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1564 59c716d95910c57b57644a6acf4dbe7e 118 SUPERFAMILY SSF46946 2 114 4.19E-46 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MCR_1564 59c716d95910c57b57644a6acf4dbe7e 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 27.012 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0419 2c43592679af4c3e4e271bb644d93945 650 Gene3D G3DSA:2.40.128.130 359 650 1.4E-35 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily MCR_0419 2c43592679af4c3e4e271bb644d93945 650 PIRSF PIRSF037375 26 650 1.2E-118 T 14-10-2018 IPR017186 Lipase, autotransporter EstA MCR_0419 2c43592679af4c3e4e271bb644d93945 650 Pfam PF00657 GDSL-like Lipase/Acylhydrolase 57 341 5.9E-9 T 14-10-2018 IPR001087 GDSL lipase/esterase GO:0016788 MCR_0419 2c43592679af4c3e4e271bb644d93945 650 SUPERFAMILY SSF103515 356 650 4.05E-31 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily MCR_0419 2c43592679af4c3e4e271bb644d93945 650 Pfam PF03797 Autotransporter beta-domain 393 629 5.8E-31 T 14-10-2018 IPR005546 Autotransporter beta-domain MCR_0419 2c43592679af4c3e4e271bb644d93945 650 Gene3D G3DSA:3.40.50.1110 43 354 2.7E-73 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MCR_0419 2c43592679af4c3e4e271bb644d93945 650 SUPERFAMILY SSF52266 56 348 1.5E-14 T 14-10-2018 MCR_0419 2c43592679af4c3e4e271bb644d93945 650 SMART SM00869 382 640 2.7E-18 T 14-10-2018 IPR005546 Autotransporter beta-domain MCR_0863 1943282c8c9b2717717ab3aefbea1fce 381 SUPERFAMILY SSF53901 202 380 1.27E-27 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0863 1943282c8c9b2717717ab3aefbea1fce 381 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 290 379 5.3E-22 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MCR_0863 1943282c8c9b2717717ab3aefbea1fce 381 Gene3D G3DSA:3.40.47.10 217 380 2.0E-37 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0863 1943282c8c9b2717717ab3aefbea1fce 381 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 151 229 7.7E-17 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MCR_0863 1943282c8c9b2717717ab3aefbea1fce 381 Gene3D G3DSA:3.40.47.10 2 213 2.7E-51 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0863 1943282c8c9b2717717ab3aefbea1fce 381 SUPERFAMILY SSF53901 1 213 5.42E-45 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0468 90faef04f760a296864481ff29d1d368 566 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 38 519 1.8E-183 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MCR_0468 90faef04f760a296864481ff29d1d368 566 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 77 519 1.1E-150 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MCR_0468 90faef04f760a296864481ff29d1d368 566 ProSitePatterns PS01303 BCCT family of transporters signature. 338 347 - T 14-10-2018 IPR018093 BCCT transporter, conserved site MCR_1168 fd84bd006021868f329afde91158237f 392 SMART SM00564 116 148 0.035 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MCR_1168 fd84bd006021868f329afde91158237f 392 SMART SM00564 202 234 0.14 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MCR_1168 fd84bd006021868f329afde91158237f 392 SMART SM00564 292 323 19.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MCR_1168 fd84bd006021868f329afde91158237f 392 SMART SM00564 254 285 610.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MCR_1168 fd84bd006021868f329afde91158237f 392 SMART SM00564 333 363 500.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MCR_1168 fd84bd006021868f329afde91158237f 392 SMART SM00564 157 188 1.9 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MCR_1168 fd84bd006021868f329afde91158237f 392 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 3 392 25.078 T 14-10-2018 IPR017687 Outer membrane protein assembly factor BamB MCR_1168 fd84bd006021868f329afde91158237f 392 Gene3D G3DSA:2.130.10.10 45 392 1.6E-113 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MCR_1168 fd84bd006021868f329afde91158237f 392 Pfam PF13360 PQQ-like domain 101 321 1.0E-40 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MCR_1168 fd84bd006021868f329afde91158237f 392 SUPERFAMILY SSF50998 101 359 1.88E-49 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MCR_1168 fd84bd006021868f329afde91158237f 392 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 8 391 2.4E-89 T 14-10-2018 IPR017687 Outer membrane protein assembly factor BamB MCR_1128 2a149c7917e260783124f91867ed4e6b 546 Pfam PF01381 Helix-turn-helix 31 90 4.7E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MCR_1128 2a149c7917e260783124f91867ed4e6b 546 SUPERFAMILY SSF47413 26 94 1.93E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MCR_1128 2a149c7917e260783124f91867ed4e6b 546 Gene3D G3DSA:3.40.640.10 189 431 3.0E-135 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_1128 2a149c7917e260783124f91867ed4e6b 546 SMART SM00530 30 90 8.6E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MCR_1128 2a149c7917e260783124f91867ed4e6b 546 Gene3D G3DSA:3.90.1150.10 158 535 3.0E-135 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_1128 2a149c7917e260783124f91867ed4e6b 546 Pfam PF00155 Aminotransferase class I and II 171 521 3.0E-51 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MCR_1128 2a149c7917e260783124f91867ed4e6b 546 Gene3D G3DSA:1.10.260.40 28 116 6.3E-11 T 14-10-2018 MCR_1128 2a149c7917e260783124f91867ed4e6b 546 SUPERFAMILY SSF53383 134 537 4.26E-92 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0333 e98ae88bdd879b729988312991014d72 146 Gene3D G3DSA:1.10.10.10 2 84 3.4E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0333 e98ae88bdd879b729988312991014d72 146 Gene3D G3DSA:3.30.1490.190 85 142 1.3E-22 T 14-10-2018 MCR_0333 e98ae88bdd879b729988312991014d72 146 SUPERFAMILY SSF46785 6 134 2.9E-43 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0333 e98ae88bdd879b729988312991014d72 146 Pfam PF01475 Ferric uptake regulator family 10 130 1.1E-42 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MCR_0194 8208ecfab863742903a86053a6d76a9b 285 SUPERFAMILY SSF53681 16 117 1.08E-33 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MCR_0194 8208ecfab863742903a86053a6d76a9b 285 SUPERFAMILY SSF53681 120 275 3.6E-26 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MCR_0194 8208ecfab863742903a86053a6d76a9b 285 TIGRFAM TIGR00067 glut_race: glutamate racemase 17 254 4.2E-58 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MCR_0194 8208ecfab863742903a86053a6d76a9b 285 Gene3D G3DSA:3.40.50.1860 16 241 1.4E-71 T 14-10-2018 MCR_0194 8208ecfab863742903a86053a6d76a9b 285 Gene3D G3DSA:3.40.50.1860 106 222 1.4E-71 T 14-10-2018 MCR_0194 8208ecfab863742903a86053a6d76a9b 285 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 81 89 - T 14-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MCR_0194 8208ecfab863742903a86053a6d76a9b 285 Pfam PF01177 Asp/Glu/Hydantoin racemase 17 229 2.1E-30 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MCR_0194 8208ecfab863742903a86053a6d76a9b 285 Hamap MF_00258 Glutamate racemase [murI]. 15 272 31.44 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MCR_1814 5d6b9bc67b683d6d64264987b0fb64ee 369 Pfam PF03739 Predicted permease YjgP/YjgQ family 8 366 1.9E-54 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 MCR_1814 5d6b9bc67b683d6d64264987b0fb64ee 369 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 5 366 1.3E-79 T 14-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 MCR_0751 d14509254a7affa125a70b996a2b07f6 425 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 191 332 1.1E-25 T 14-10-2018 IPR001453 MoaB/Mog domain MCR_0751 d14509254a7affa125a70b996a2b07f6 425 Gene3D G3DSA:3.40.980.10 189 346 2.5E-117 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily MCR_0751 d14509254a7affa125a70b996a2b07f6 425 SUPERFAMILY SSF63867 348 424 4.84E-17 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0751 d14509254a7affa125a70b996a2b07f6 425 Gene3D G3DSA:3.90.105.10 33 188 2.5E-117 T 14-10-2018 MCR_0751 d14509254a7affa125a70b996a2b07f6 425 SUPERFAMILY SSF63882 25 189 6.15E-45 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0751 d14509254a7affa125a70b996a2b07f6 425 SUPERFAMILY SSF53218 190 340 3.14E-35 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily MCR_0751 d14509254a7affa125a70b996a2b07f6 425 Gene3D G3DSA:2.170.190.11 54 155 2.5E-117 T 14-10-2018 MCR_0751 d14509254a7affa125a70b996a2b07f6 425 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 268 301 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 MCR_0751 d14509254a7affa125a70b996a2b07f6 425 Pfam PF03454 MoeA C-terminal region (domain IV) 351 420 1.0E-11 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0751 d14509254a7affa125a70b996a2b07f6 425 Pfam PF03453 MoeA N-terminal region (domain I and II) 4 181 2.2E-37 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0751 d14509254a7affa125a70b996a2b07f6 425 SMART SM00852 194 336 9.9E-34 T 14-10-2018 IPR001453 MoaB/Mog domain MCR_0751 d14509254a7affa125a70b996a2b07f6 425 Pfam PF00994 Probable molybdopterin binding domain 195 334 2.0E-21 T 14-10-2018 IPR001453 MoaB/Mog domain MCR_0751 d14509254a7affa125a70b996a2b07f6 425 Gene3D G3DSA:2.40.340.10 347 416 2.5E-117 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0623 7893e405aaea1d8c5bcda2744ea568de 940 Gene3D G3DSA:2.40.128.130 641 940 1.5E-24 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily MCR_0623 7893e405aaea1d8c5bcda2744ea568de 940 SUPERFAMILY SSF48317 146 243 6.54E-19 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MCR_0623 7893e405aaea1d8c5bcda2744ea568de 940 Pfam PF01569 PAP2 superfamily 146 242 7.2E-12 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MCR_0623 7893e405aaea1d8c5bcda2744ea568de 940 SMART SM00869 681 929 7.6E-9 T 14-10-2018 IPR005546 Autotransporter beta-domain MCR_0623 7893e405aaea1d8c5bcda2744ea568de 940 SUPERFAMILY SSF103515 667 940 5.49E-22 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily MCR_0623 7893e405aaea1d8c5bcda2744ea568de 940 Gene3D G3DSA:1.20.144.10 31 274 3.2E-41 T 14-10-2018 MCR_0623 7893e405aaea1d8c5bcda2744ea568de 940 SMART SM00014 138 253 0.0016 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MCR_0539 66d0f5d9fb01e702746d0915bb3dcfd0 241 PIRSF PIRSF005650 3 241 1.1E-85 T 14-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 MCR_0539 66d0f5d9fb01e702746d0915bb3dcfd0 241 SUPERFAMILY SSF53633 7 240 7.59E-65 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MCR_0539 66d0f5d9fb01e702746d0915bb3dcfd0 241 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 239 4.1E-93 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MCR_0539 66d0f5d9fb01e702746d0915bb3dcfd0 241 Hamap MF_01220_B Uridylate kinase [pyrH]. 6 240 41.224 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MCR_0539 66d0f5d9fb01e702746d0915bb3dcfd0 241 Pfam PF00696 Amino acid kinase family 10 219 5.3E-25 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MCR_0539 66d0f5d9fb01e702746d0915bb3dcfd0 241 Gene3D G3DSA:3.40.1160.10 1 241 1.5E-67 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MCR_1318 10c88807d7e8baf60706792682fb150d 287 Pfam PF00793 DAHP synthetase I family 15 278 2.4E-72 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MCR_1318 10c88807d7e8baf60706792682fb150d 287 Gene3D G3DSA:3.20.20.70 3 287 1.7E-97 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1318 10c88807d7e8baf60706792682fb150d 287 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 24 279 1.6E-113 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MCR_1318 10c88807d7e8baf60706792682fb150d 287 SUPERFAMILY SSF51569 10 282 1.19E-101 T 14-10-2018 MCR_1318 10c88807d7e8baf60706792682fb150d 287 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 19 281 48.5 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 SUPERFAMILY SSF50249 1 63 1.26E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 Pfam PF01330 RuvA N terminal domain 1 62 1.6E-15 T 14-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 SUPERFAMILY SSF47781 66 135 1.14E-20 T 14-10-2018 IPR010994 RuvA domain 2-like MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 201 3.6E-51 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 Pfam PF07499 RuvA, C-terminal domain 159 202 2.7E-12 T 14-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 Gene3D G3DSA:2.40.50.140 1 63 1.7E-17 T 14-10-2018 MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 202 28.979 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 SMART SM00278 108 127 0.022 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 SMART SM00278 73 92 2.8 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 Pfam PF14520 Helix-hairpin-helix domain 72 129 9.9E-18 T 14-10-2018 MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 Gene3D G3DSA:1.10.8.10 149 203 1.3E-8 T 14-10-2018 MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 Gene3D G3DSA:1.10.150.20 67 139 5.9E-26 T 14-10-2018 MCR_1027 cd0196f22ebe8702d9d72d30f20b5042 204 SUPERFAMILY SSF46929 158 202 4.19E-9 T 14-10-2018 IPR036267 RuvA, C-terminal domain superfamily MCR_1353 480f6804f91542a4a789eb09729d85fa 143 PIRSF PIRSF002181 1 143 1.9E-51 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MCR_1353 480f6804f91542a4a789eb09729d85fa 143 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 142 29.448 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MCR_1353 480f6804f91542a4a789eb09729d85fa 143 SUPERFAMILY SSF52161 6 142 5.76E-59 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 MCR_1353 480f6804f91542a4a789eb09729d85fa 143 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 143 4.1E-64 T 14-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1353 480f6804f91542a4a789eb09729d85fa 143 Gene3D G3DSA:3.90.1180.10 2 143 7.7E-63 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 MCR_1353 480f6804f91542a4a789eb09729d85fa 143 Pfam PF00572 Ribosomal protein L13 16 139 1.5E-58 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MCR_1678 a65373823a99949ec036487f2a4c359c 745 SMART SM00434 8 461 8.5E-213 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_1678 a65373823a99949ec036487f2a4c359c 745 SUPERFAMILY SSF101904 497 736 2.35E-46 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MCR_1678 a65373823a99949ec036487f2a4c359c 745 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 599 633 2.2 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MCR_1678 a65373823a99949ec036487f2a4c359c 745 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 653 690 0.001 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MCR_1678 a65373823a99949ec036487f2a4c359c 745 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 9 736 1.3E-289 T 14-10-2018 MCR_1678 a65373823a99949ec036487f2a4c359c 745 Gene3D G3DSA:2.120.10.90 500 725 2.8E-17 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MCR_1678 a65373823a99949ec036487f2a4c359c 745 Gene3D G3DSA:3.90.199.10 29 481 1.5E-174 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MCR_1678 a65373823a99949ec036487f2a4c359c 745 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 29 468 4.2E-136 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MCR_1678 a65373823a99949ec036487f2a4c359c 745 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 1 738 32.682 T 14-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MCR_1678 a65373823a99949ec036487f2a4c359c 745 SUPERFAMILY SSF56719 28 483 3.66E-152 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MCR_1678 a65373823a99949ec036487f2a4c359c 745 Gene3D G3DSA:3.30.1360.40 235 331 1.5E-174 T 14-10-2018 MCR_1678 a65373823a99949ec036487f2a4c359c 745 Gene3D G3DSA:1.10.268.10 369 454 1.5E-174 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MCR_1554 f46355eced5ec9da787cc01f411d4d1f 319 SUPERFAMILY SSF52151 12 316 2.62E-69 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MCR_1554 f46355eced5ec9da787cc01f411d4d1f 319 Pfam PF00698 Acyl transferase domain 15 287 5.1E-28 T 14-10-2018 IPR014043 Acyl transferase MCR_1554 f46355eced5ec9da787cc01f411d4d1f 319 PIRSF PIRSF000446 8 319 1.3E-101 T 14-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MCR_1554 f46355eced5ec9da787cc01f411d4d1f 319 SUPERFAMILY SSF55048 139 202 3.66E-13 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding MCR_1554 f46355eced5ec9da787cc01f411d4d1f 319 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 11 297 1.3E-96 T 14-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MCR_1554 f46355eced5ec9da787cc01f411d4d1f 319 Gene3D G3DSA:3.30.70.250 137 206 1.3E-85 T 14-10-2018 MCR_1554 f46355eced5ec9da787cc01f411d4d1f 319 Gene3D G3DSA:3.40.366.10 13 296 1.3E-85 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 MCR_1554 f46355eced5ec9da787cc01f411d4d1f 319 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 15 308 3.7E-24 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain MCR_1432 82834f9672912716f05cadf779ec36b5 322 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1432 82834f9672912716f05cadf779ec36b5 322 Gene3D G3DSA:3.40.50.300 3 246 4.7E-66 T 14-10-2018 MCR_1432 82834f9672912716f05cadf779ec36b5 322 SUPERFAMILY SSF52540 13 240 1.15E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1432 82834f9672912716f05cadf779ec36b5 322 Pfam PF00005 ABC transporter 31 175 2.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1432 82834f9672912716f05cadf779ec36b5 322 SMART SM00382 40 239 1.1E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0902 24b16197c54a2e60a990b9c7233abbdf 400 Gene3D G3DSA:2.40.37.10 19 400 2.2E-134 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MCR_0902 24b16197c54a2e60a990b9c7233abbdf 400 SUPERFAMILY SSF51419 27 256 6.21E-41 T 14-10-2018 IPR029066 PLP-binding barrel MCR_0902 24b16197c54a2e60a990b9c7233abbdf 400 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 257 356 1.0E-10 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MCR_0902 24b16197c54a2e60a990b9c7233abbdf 400 Gene3D G3DSA:3.20.20.10 28 256 2.2E-134 T 14-10-2018 IPR029066 PLP-binding barrel MCR_0902 24b16197c54a2e60a990b9c7233abbdf 400 SUPERFAMILY SSF50621 226 389 1.21E-29 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MCR_0902 24b16197c54a2e60a990b9c7233abbdf 400 PIRSF PIRSF038941 9 400 3.9E-136 T 14-10-2018 IPR005730 Carboxynorspermidine decarboxylase GO:0016831|GO:0045312 KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 MCR_0486 40ca68bcc7eebb2b150843dfbbe6aaa6 224 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 18 202 27.379 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MCR_0486 40ca68bcc7eebb2b150843dfbbe6aaa6 224 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 14 196 5.5E-71 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MCR_0486 40ca68bcc7eebb2b150843dfbbe6aaa6 224 Gene3D G3DSA:3.40.50.300 7 208 1.1E-49 T 14-10-2018 MCR_0486 40ca68bcc7eebb2b150843dfbbe6aaa6 224 Pfam PF01926 50S ribosome-binding GTPase 32 151 2.1E-18 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_0486 40ca68bcc7eebb2b150843dfbbe6aaa6 224 SUPERFAMILY SSF52540 25 207 8.85E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1163 3a8a9e6c6870463086c2aca06e904eb1 233 SUPERFAMILY SSF160443 152 229 3.66E-11 T 14-10-2018 IPR036063 Smr domain superfamily MCR_1163 3a8a9e6c6870463086c2aca06e904eb1 233 Gene3D G3DSA:3.30.1370.110 109 233 9.1E-32 T 14-10-2018 MCR_1163 3a8a9e6c6870463086c2aca06e904eb1 233 SMART SM00463 150 229 9.9E-14 T 14-10-2018 IPR002625 Smr domain MCR_1163 3a8a9e6c6870463086c2aca06e904eb1 233 Pfam PF01713 Smr domain 153 229 2.0E-19 T 14-10-2018 IPR002625 Smr domain MCR_1813 cfa4a6f67b5e852c48dd5801a571852c 386 Pfam PF07759 Protein of unknown function (DUF1615) 45 378 2.3E-121 T 14-10-2018 IPR011673 Protein of unknown function DUF1615 MCR_1813 cfa4a6f67b5e852c48dd5801a571852c 386 ProDom PD041438 LIPOPROTEIN YAIW PRECURSOR SIGNAL MEMBRANE OUTER LIPOPROTEIN ECS0428 XAC0592 SECRETED 14 377 9.0E-107 T 14-10-2018 IPR011673 Protein of unknown function DUF1615 MCR_1440 2910b96e27ee9211486d0de69fdddf14 216 Pfam PF04351 Pilus assembly protein, PilP 100 210 8.6E-28 T 14-10-2018 IPR007446 Pilus assembly protein PilP MCR_1440 2910b96e27ee9211486d0de69fdddf14 216 Gene3D G3DSA:2.30.30.830 122 212 2.3E-24 T 14-10-2018 MCR_0510 74db4fb752f0ac8f2a33887726e5af4d 107 SUPERFAMILY SSF54862 1 100 1.09E-24 T 14-10-2018 MCR_0510 74db4fb752f0ac8f2a33887726e5af4d 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 4.1E-18 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 MCR_0510 74db4fb752f0ac8f2a33887726e5af4d 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 4.1E-18 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 MCR_0510 74db4fb752f0ac8f2a33887726e5af4d 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 4.1E-18 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 MCR_0510 74db4fb752f0ac8f2a33887726e5af4d 107 Pfam PF00037 4Fe-4S binding domain 34 55 5.6E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MCR_0510 74db4fb752f0ac8f2a33887726e5af4d 107 Pfam PF11953 Domain of unknown function (DUF3470) 66 107 9.0E-22 T 14-10-2018 IPR022569 Ferredoxin, C-terminal MCR_0510 74db4fb752f0ac8f2a33887726e5af4d 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MCR_0510 74db4fb752f0ac8f2a33887726e5af4d 107 Gene3D G3DSA:3.30.70.20 2 96 2.7E-31 T 14-10-2018 MCR_0758 d50a08886f9bc3b07ec8a3c86cdfa980 163 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 9 159 1.9E-51 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0758 d50a08886f9bc3b07ec8a3c86cdfa980 163 SUPERFAMILY SSF55040 16 161 9.42E-51 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0758 d50a08886f9bc3b07ec8a3c86cdfa980 163 Pfam PF01967 MoaC family 20 157 1.8E-47 T 14-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0758 d50a08886f9bc3b07ec8a3c86cdfa980 163 Gene3D G3DSA:3.30.70.640 6 163 8.6E-59 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 16 616 9.3E-261 T 14-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 Pfam PF00890 FAD binding domain 18 422 1.7E-113 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 SUPERFAMILY SSF51905 12 450 2.74E-78 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 Gene3D G3DSA:3.50.50.60 18 433 3.0E-162 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 52 61 - T 14-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 PIRSF PIRSF000171 8 603 5.8E-36 T 14-10-2018 MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 Gene3D G3DSA:3.90.700.10 255 358 3.0E-162 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 Pfam PF02910 Fumarate reductase flavoprotein C-term 480 614 3.4E-32 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 SUPERFAMILY SSF46977 471 616 6.8E-36 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 SUPERFAMILY SSF56425 245 364 1.79E-40 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 Gene3D G3DSA:1.20.58.100 452 565 8.5E-30 T 14-10-2018 MCR_0068 d149a1e502fef9f3b9b53aa4fd6da8d6 616 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 18 615 7.1E-227 T 14-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0906 1207b1e4ac4d72e1b133077ddce89dde 148 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 9 144 5.3E-36 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MCR_0906 1207b1e4ac4d72e1b133077ddce89dde 148 SUPERFAMILY SSF52540 30 129 2.12E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0906 1207b1e4ac4d72e1b133077ddce89dde 148 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 134 3.7E-38 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MCR_0906 1207b1e4ac4d72e1b133077ddce89dde 148 Gene3D G3DSA:3.40.50.300 2 147 1.7E-39 T 14-10-2018 MCR_0128 91d087426449e0af57aaa6ec0f05e09e 269 SUPERFAMILY SSF141734 4 120 7.45E-46 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MCR_0128 91d087426449e0af57aaa6ec0f05e09e 269 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 157 252 1.2E-23 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MCR_0128 91d087426449e0af57aaa6ec0f05e09e 269 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 111 30.972 T 14-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MCR_0128 91d087426449e0af57aaa6ec0f05e09e 269 Gene3D G3DSA:3.10.20.400 2 98 4.0E-36 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MCR_0128 91d087426449e0af57aaa6ec0f05e09e 269 Gene3D G3DSA:1.10.287.1080 153 258 3.0E-26 T 14-10-2018 MCR_0128 91d087426449e0af57aaa6ec0f05e09e 269 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 154 252 19.383 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MCR_0128 91d087426449e0af57aaa6ec0f05e09e 269 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 110 2.0E-21 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MCR_0128 91d087426449e0af57aaa6ec0f05e09e 269 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 9 257 33.623 T 14-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 MCR_0128 91d087426449e0af57aaa6ec0f05e09e 269 SUPERFAMILY SSF101386 156 258 2.4E-18 T 14-10-2018 MCR_0128 91d087426449e0af57aaa6ec0f05e09e 269 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 107 6.2E-32 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MCR_0128 91d087426449e0af57aaa6ec0f05e09e 269 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 159 253 2.1E-10 T 14-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 MCR_1584 6ec928dabb89c88aa878dfd3aa9e14dc 200 Pfam PF00573 Ribosomal protein L4/L1 family 11 197 4.0E-64 T 14-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 MCR_1584 6ec928dabb89c88aa878dfd3aa9e14dc 200 SUPERFAMILY SSF52166 9 199 4.97E-72 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 MCR_1584 6ec928dabb89c88aa878dfd3aa9e14dc 200 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 11 197 2.5E-73 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1584 6ec928dabb89c88aa878dfd3aa9e14dc 200 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 2 200 33.548 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1584 6ec928dabb89c88aa878dfd3aa9e14dc 200 Gene3D G3DSA:3.40.1370.10 1 200 4.2E-70 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 MCR_1680 2e2a9ee7fd25f39a0aa90186f41c6af2 289 SUPERFAMILY SSF103481 49 148 8.76E-13 T 14-10-2018 MCR_1680 2e2a9ee7fd25f39a0aa90186f41c6af2 289 SUPERFAMILY SSF103481 191 286 4.18E-9 T 14-10-2018 MCR_1680 2e2a9ee7fd25f39a0aa90186f41c6af2 289 Pfam PF00892 EamA-like transporter family 13 145 8.8E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MCR_1680 2e2a9ee7fd25f39a0aa90186f41c6af2 289 Pfam PF00892 EamA-like transporter family 158 283 2.1E-7 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MCR_1694 aa5fa498ca5dec761e31ff7d465335db 240 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 116 2.4E-19 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MCR_1694 aa5fa498ca5dec761e31ff7d465335db 240 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 218 3.7E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_1694 aa5fa498ca5dec761e31ff7d465335db 240 SUPERFAMILY SSF161098 9 208 4.06E-41 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1694 aa5fa498ca5dec761e31ff7d465335db 240 Gene3D G3DSA:1.10.3720.10 3 224 1.8E-49 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 514 6.9E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 Gene3D G3DSA:1.10.287.130 248 315 1.0E-9 T 14-10-2018 MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 Gene3D G3DSA:1.20.1480.50 168 246 2.8E-10 T 14-10-2018 MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 SUPERFAMILY SSF55874 304 513 8.5E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 SMART SM00388 243 314 2.0E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 314 7.6E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 SUPERFAMILY SSF47384 226 315 3.73E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 Pfam PF00672 HAMP domain 195 238 3.9E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 SMART SM00304 190 242 2.5E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 SUPERFAMILY SSF158472 191 241 1.7E-8 T 14-10-2018 MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 SMART SM00387 350 515 1.4E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 1.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 473 1.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0179 bda5fe5e65ad62fd1a23d7da1cb4bf45 521 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 494 1.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MCR_0352 76066ba361df828ed89b264e972a59c2 209 ProSitePatterns PS00856 Guanylate kinase-like signature. 37 54 - T 14-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 MCR_0352 76066ba361df828ed89b264e972a59c2 209 SUPERFAMILY SSF52540 3 185 1.56E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0352 76066ba361df828ed89b264e972a59c2 209 Gene3D G3DSA:3.40.50.300 7 180 1.7E-66 T 14-10-2018 MCR_0352 76066ba361df828ed89b264e972a59c2 209 Hamap MF_00328 Guanylate kinase [gmk]. 1 184 34.905 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MCR_0352 76066ba361df828ed89b264e972a59c2 209 SMART SM00072 2 184 3.5E-60 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MCR_0352 76066ba361df828ed89b264e972a59c2 209 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 3 181 3.5E-72 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MCR_0352 76066ba361df828ed89b264e972a59c2 209 Gene3D G3DSA:3.30.63.10 34 93 1.7E-66 T 14-10-2018 MCR_0352 76066ba361df828ed89b264e972a59c2 209 Pfam PF00625 Guanylate kinase 4 182 8.8E-51 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MCR_0400 a7a9cefd17b95831e3d71e735b596ffc 276 Pfam PF01012 Electron transfer flavoprotein domain 58 233 8.7E-45 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MCR_0400 a7a9cefd17b95831e3d71e735b596ffc 276 Gene3D G3DSA:3.40.50.620 26 275 2.3E-83 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0400 a7a9cefd17b95831e3d71e735b596ffc 276 SUPERFAMILY SSF52402 28 269 1.12E-80 T 14-10-2018 MCR_0400 a7a9cefd17b95831e3d71e735b596ffc 276 SMART SM00893 50 238 4.2E-65 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MCR_0400 a7a9cefd17b95831e3d71e735b596ffc 276 PIRSF PIRSF000090 28 276 4.9E-82 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MCR_0400 a7a9cefd17b95831e3d71e735b596ffc 276 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 182 202 - T 14-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MCR_0843 efbaa4ed9acd201f4f826e5872ed2ce6 407 SMART SM00341 230 309 9.1E-5 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MCR_0843 efbaa4ed9acd201f4f826e5872ed2ce6 407 SUPERFAMILY SSF47819 317 390 1.57E-5 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 MCR_0843 efbaa4ed9acd201f4f826e5872ed2ce6 407 Pfam PF01612 3'-5' exonuclease 25 189 1.7E-21 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MCR_0843 efbaa4ed9acd201f4f826e5872ed2ce6 407 SUPERFAMILY SSF53098 13 207 1.09E-46 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MCR_0843 efbaa4ed9acd201f4f826e5872ed2ce6 407 Gene3D G3DSA:3.30.420.10 23 212 8.2E-46 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MCR_0843 efbaa4ed9acd201f4f826e5872ed2ce6 407 SUPERFAMILY SSF47819 213 318 1.11E-21 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 MCR_0843 efbaa4ed9acd201f4f826e5872ed2ce6 407 Gene3D G3DSA:1.10.150.80 226 312 1.8E-17 T 14-10-2018 MCR_0843 efbaa4ed9acd201f4f826e5872ed2ce6 407 Pfam PF00570 HRDC domain 233 299 5.4E-15 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MCR_0843 efbaa4ed9acd201f4f826e5872ed2ce6 407 SMART SM00474 23 190 2.5E-24 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MCR_0810 13e73c619267cd212631ad5aac4135fc 189 Gene3D G3DSA:1.20.910.10 1 188 3.3E-48 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MCR_0810 13e73c619267cd212631ad5aac4135fc 189 Pfam PF01126 Heme oxygenase 5 183 4.8E-30 T 14-10-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 MCR_0810 13e73c619267cd212631ad5aac4135fc 189 SUPERFAMILY SSF48613 6 187 4.13E-46 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MCR_1710 ae09d12ea648365027234bed188ce0ed 164 SUPERFAMILY SSF52374 6 159 4.29E-45 T 14-10-2018 MCR_1710 ae09d12ea648365027234bed188ce0ed 164 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 6 162 35.299 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MCR_1710 ae09d12ea648365027234bed188ce0ed 164 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 61 2.7E-17 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MCR_1710 ae09d12ea648365027234bed188ce0ed 164 Pfam PF01467 Cytidylyltransferase-like 9 137 1.9E-20 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MCR_1710 ae09d12ea648365027234bed188ce0ed 164 Gene3D G3DSA:3.40.50.620 1 163 2.0E-58 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_1710 ae09d12ea648365027234bed188ce0ed 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 116 138 4.5E-44 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MCR_1710 ae09d12ea648365027234bed188ce0ed 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 24 45 4.5E-44 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MCR_1710 ae09d12ea648365027234bed188ce0ed 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 53 77 4.5E-44 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MCR_1710 ae09d12ea648365027234bed188ce0ed 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 6 24 4.5E-44 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MCR_1710 ae09d12ea648365027234bed188ce0ed 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 89 105 4.5E-44 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MCR_1710 ae09d12ea648365027234bed188ce0ed 164 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 8 160 8.1E-58 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MCR_0995 3b1ba5c9dd161e4a669febb7014f4647 391 SMART SM00490 271 351 6.1E-31 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0995 3b1ba5c9dd161e4a669febb7014f4647 391 SUPERFAMILY SSF52540 84 371 3.79E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0995 3b1ba5c9dd161e4a669febb7014f4647 391 Pfam PF00271 Helicase conserved C-terminal domain 244 351 2.9E-29 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0995 3b1ba5c9dd161e4a669febb7014f4647 391 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 6 389 47.997 T 14-10-2018 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 MCR_0995 3b1ba5c9dd161e4a669febb7014f4647 391 SMART SM00487 26 235 2.2E-55 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MCR_0995 3b1ba5c9dd161e4a669febb7014f4647 391 Gene3D G3DSA:3.40.50.300 1 223 1.1E-73 T 14-10-2018 MCR_0995 3b1ba5c9dd161e4a669febb7014f4647 391 Pfam PF00270 DEAD/DEAH box helicase 31 208 2.6E-48 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MCR_0995 3b1ba5c9dd161e4a669febb7014f4647 391 Gene3D G3DSA:3.40.50.300 226 390 5.5E-49 T 14-10-2018 MCR_0995 3b1ba5c9dd161e4a669febb7014f4647 391 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 164 172 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MCR_1649 869530e7d080c5853d5a07d959eb9d2f 219 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 87 109 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MCR_1649 869530e7d080c5853d5a07d959eb9d2f 219 PIRSF PIRSF000847 13 219 7.2E-45 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MCR_1649 869530e7d080c5853d5a07d959eb9d2f 219 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 16 217 5.4E-54 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MCR_1649 869530e7d080c5853d5a07d959eb9d2f 219 Pfam PF01066 CDP-alcohol phosphatidyltransferase 17 109 2.9E-16 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MCR_1649 869530e7d080c5853d5a07d959eb9d2f 219 Gene3D G3DSA:1.20.120.1760 7 212 1.1E-11 T 14-10-2018 MCR_0014 f523e4273115e158c00f6e66a83957b2 418 SUPERFAMILY SSF54373 270 359 7.59E-15 T 14-10-2018 MCR_0014 f523e4273115e158c00f6e66a83957b2 418 Pfam PF01266 FAD dependent oxidoreductase 2 396 8.1E-71 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MCR_0014 f523e4273115e158c00f6e66a83957b2 418 Gene3D G3DSA:3.50.50.60 105 404 4.8E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0014 f523e4273115e158c00f6e66a83957b2 418 Gene3D G3DSA:3.30.9.10 134 361 4.8E-54 T 14-10-2018 MCR_0014 f523e4273115e158c00f6e66a83957b2 418 SUPERFAMILY SSF51905 1 415 3.75E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0014 f523e4273115e158c00f6e66a83957b2 418 Gene3D G3DSA:3.50.50.60 1 69 9.4E-14 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0014 f523e4273115e158c00f6e66a83957b2 418 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 410 47.348 T 14-10-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 230 2.2E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 277 295 2.2E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 231 249 2.2E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 Pfam PF01926 50S ribosome-binding GTPase 210 327 1.2E-22 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 PIRSF PIRSF006809 6 430 5.3E-145 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 Hamap MF_00900 GTPase HflX [hflX]. 29 398 48.063 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 13 368 1.8E-146 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 Gene3D G3DSA:3.40.50.300 207 375 5.0E-40 T 14-10-2018 MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 Pfam PF16360 GTP-binding GTPase Middle Region 124 202 2.1E-28 T 14-10-2018 IPR032305 GTP-binding protein, middle domain MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 Pfam PF13167 GTP-binding GTPase N-terminal 28 122 6.3E-27 T 14-10-2018 IPR025121 GTPase HflX, N-terminal MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 SUPERFAMILY SSF52540 207 384 2.21E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0683 ae937c8fbdbbdceb199a799647e7e285 469 Gene3D G3DSA:3.40.50.11060 19 148 2.8E-34 T 14-10-2018 MCR_1847 f90d54e7d9e7a7f6b3c39b36d2005648 307 Pfam PF00589 Phage integrase family 122 292 6.6E-46 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MCR_1847 f90d54e7d9e7a7f6b3c39b36d2005648 307 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 20 307 52.826 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD MCR_1847 f90d54e7d9e7a7f6b3c39b36d2005648 307 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 29 306 8.5E-102 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MCR_1847 f90d54e7d9e7a7f6b3c39b36d2005648 307 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 27 98 5.6E-8 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MCR_1847 f90d54e7d9e7a7f6b3c39b36d2005648 307 Gene3D G3DSA:1.10.443.10 120 301 4.6E-64 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MCR_1847 f90d54e7d9e7a7f6b3c39b36d2005648 307 Gene3D G3DSA:1.10.150.130 19 117 9.2E-10 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal MCR_1847 f90d54e7d9e7a7f6b3c39b36d2005648 307 SUPERFAMILY SSF56349 117 305 2.71E-55 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MCR_1847 f90d54e7d9e7a7f6b3c39b36d2005648 307 SUPERFAMILY SSF47823 28 108 8.24E-10 T 14-10-2018 MCR_0476 077c087c55e112ec02170f35424a3e7f 507 Gene3D G3DSA:2.20.200.10 114 366 3.8E-123 T 14-10-2018 MCR_0476 077c087c55e112ec02170f35424a3e7f 507 SUPERFAMILY SSF56954 5 477 4.71E-96 T 14-10-2018 MCR_0476 077c087c55e112ec02170f35424a3e7f 507 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 15 477 1.8E-108 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 MCR_0476 077c087c55e112ec02170f35424a3e7f 507 Gene3D G3DSA:1.20.1600.10 66 477 3.8E-123 T 14-10-2018 MCR_0476 077c087c55e112ec02170f35424a3e7f 507 Pfam PF02321 Outer membrane efflux protein 297 475 6.0E-27 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MCR_0476 077c087c55e112ec02170f35424a3e7f 507 Pfam PF02321 Outer membrane efflux protein 77 262 1.5E-22 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MCR_0143 0e6104c0442d54579ceeaa045898fa6e 86 PRINTS PR01249 Ribosomal protein L31 signature 2 19 4.0E-15 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0143 0e6104c0442d54579ceeaa045898fa6e 86 PRINTS PR01249 Ribosomal protein L31 signature 59 77 4.0E-15 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0143 0e6104c0442d54579ceeaa045898fa6e 86 PRINTS PR01249 Ribosomal protein L31 signature 44 59 4.0E-15 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0143 0e6104c0442d54579ceeaa045898fa6e 86 SUPERFAMILY SSF143800 1 80 3.92E-23 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0143 0e6104c0442d54579ceeaa045898fa6e 86 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 6.1E-18 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0143 0e6104c0442d54579ceeaa045898fa6e 86 Pfam PF01197 Ribosomal protein L31 1 78 3.0E-26 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0143 0e6104c0442d54579ceeaa045898fa6e 86 Gene3D G3DSA:2.30.170.50 1 83 5.8E-24 T 14-10-2018 MCR_0143 0e6104c0442d54579ceeaa045898fa6e 86 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 80 25.202 T 14-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0143 0e6104c0442d54579ceeaa045898fa6e 86 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0564 d2f1dfe77ff433116680e824d78eee03 201 Gene3D G3DSA:3.60.15.10 74 199 9.9E-23 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MCR_0564 d2f1dfe77ff433116680e824d78eee03 201 SUPERFAMILY SSF56281 87 171 2.52E-11 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MCR_0564 d2f1dfe77ff433116680e824d78eee03 201 Pfam PF12706 Beta-lactamase superfamily domain 121 171 4.4E-10 T 14-10-2018 IPR001279 Metallo-beta-lactamase MCR_1811 03ccedcfb923b6a931bcf7b4821f4360 320 Pfam PF13622 Thioesterase-like superfamily 45 308 2.3E-47 T 14-10-2018 MCR_1811 03ccedcfb923b6a931bcf7b4821f4360 320 SUPERFAMILY SSF54637 143 309 1.86E-47 T 14-10-2018 IPR029069 HotDog domain superfamily MCR_1811 03ccedcfb923b6a931bcf7b4821f4360 320 Gene3D G3DSA:3.10.129.90 16 312 7.1E-88 T 14-10-2018 MCR_1811 03ccedcfb923b6a931bcf7b4821f4360 320 SUPERFAMILY SSF54637 19 141 2.98E-31 T 14-10-2018 IPR029069 HotDog domain superfamily MCR_1641 10e3e866e6bbd8a8012c0c42015bbd94 692 SUPERFAMILY SSF109604 350 493 5.89E-19 T 14-10-2018 MCR_1641 10e3e866e6bbd8a8012c0c42015bbd94 692 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 396 415 6.3E-31 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1641 10e3e866e6bbd8a8012c0c42015bbd94 692 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 320 336 6.3E-31 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1641 10e3e866e6bbd8a8012c0c42015bbd94 692 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 5 18 6.3E-31 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1641 10e3e866e6bbd8a8012c0c42015bbd94 692 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 248 263 6.3E-31 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1641 10e3e866e6bbd8a8012c0c42015bbd94 692 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 48 60 6.3E-31 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1641 10e3e866e6bbd8a8012c0c42015bbd94 692 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 691 4.1E-227 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1641 10e3e866e6bbd8a8012c0c42015bbd94 692 SMART SM00836 588 687 0.0015 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MCR_1641 10e3e866e6bbd8a8012c0c42015bbd94 692 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 553 5.0E-194 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1641 10e3e866e6bbd8a8012c0c42015bbd94 692 Pfam PF05746 DALR anticodon binding domain 586 681 9.4E-10 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MCR_1641 10e3e866e6bbd8a8012c0c42015bbd94 692 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 1 690 24.002 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MCR_1734 18d0f0068315b6fbe6c8108ca3819f46 379 SUPERFAMILY SSF53850 57 369 4.14E-93 T 14-10-2018 MCR_1734 18d0f0068315b6fbe6c8108ca3819f46 379 PIRSF PIRSF002756 3 371 4.2E-106 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MCR_1734 18d0f0068315b6fbe6c8108ca3819f46 379 Gene3D G3DSA:3.40.190.10 58 355 3.3E-116 T 14-10-2018 MCR_1734 18d0f0068315b6fbe6c8108ca3819f46 379 Pfam PF12849 PBP superfamily domain 46 340 8.9E-65 T 14-10-2018 IPR024370 PBP domain MCR_1734 18d0f0068315b6fbe6c8108ca3819f46 379 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 57 368 1.4E-110 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MCR_1734 18d0f0068315b6fbe6c8108ca3819f46 379 Gene3D G3DSA:3.40.190.10 131 309 3.3E-116 T 14-10-2018 MCR_1579 b8171655183f645e7c0e4c491a999198 240 SUPERFAMILY SSF54814 2 106 1.91E-36 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MCR_1579 b8171655183f645e7c0e4c491a999198 240 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 5.1E-40 T 14-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1579 b8171655183f645e7c0e4c491a999198 240 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.865 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MCR_1579 b8171655183f645e7c0e4c491a999198 240 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 14-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1579 b8171655183f645e7c0e4c491a999198 240 SUPERFAMILY SSF54821 108 206 5.62E-39 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1579 b8171655183f645e7c0e4c491a999198 240 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 1.1E-93 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MCR_1579 b8171655183f645e7c0e4c491a999198 240 SMART SM00322 60 125 2.8E-7 T 14-10-2018 IPR004087 K Homology domain GO:0003676 MCR_1579 b8171655183f645e7c0e4c491a999198 240 Pfam PF07650 KH domain 39 110 8.1E-19 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1579 b8171655183f645e7c0e4c491a999198 240 Gene3D G3DSA:3.30.1140.32 108 208 1.4E-43 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1579 b8171655183f645e7c0e4c491a999198 240 Gene3D G3DSA:3.30.300.20 18 107 1.9E-27 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MCR_1640 b2c746111c3d38f3d0bd289a7f57e84e 77 Pfam PF13356 Arm DNA-binding domain 8 76 4.1E-13 T 14-10-2018 IPR025166 Integrase, DNA-binding domain MCR_1640 b2c746111c3d38f3d0bd289a7f57e84e 77 Gene3D G3DSA:3.30.160.390 6 77 8.8E-23 T 14-10-2018 IPR038488 Integrase, DNA-binding domain superfamily MCR_1428 6953893184351e22b036ef9095dfbd1b 211 Gene3D G3DSA:3.20.20.70 1 211 3.0E-60 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1428 6953893184351e22b036ef9095dfbd1b 211 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 4 208 4.4E-45 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MCR_1428 6953893184351e22b036ef9095dfbd1b 211 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 211 34.845 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MCR_1428 6953893184351e22b036ef9095dfbd1b 211 SUPERFAMILY SSF51366 4 211 8.48E-55 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MCR_0175 cda03fb83b9ec381329275710590bb14 173 SUPERFAMILY SSF82093 31 136 4.45E-34 T 14-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 MCR_0175 cda03fb83b9ec381329275710590bb14 173 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 141 30.716 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 MCR_0175 cda03fb83b9ec381329275710590bb14 173 Gene3D G3DSA:2.40.50.140 30 137 2.7E-35 T 14-10-2018 MCR_0175 cda03fb83b9ec381329275710590bb14 173 Pfam PF03100 CcmE 5 131 3.8E-43 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 461 477 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 416 556 7.8E-15 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 271 7.5E-41 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 351 403 2.3E-13 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 53 110 3.6E-17 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 SUPERFAMILY SSF56014 412 557 1.01E-36 T 14-10-2018 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 SUPERFAMILY SSF56014 120 273 8.11E-48 T 14-10-2018 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 SUPERFAMILY SSF55124 1 125 4.25E-29 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 Gene3D G3DSA:3.90.480.10 53 391 7.9E-78 T 14-10-2018 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 Gene3D G3DSA:3.30.413.10 412 558 1.2E-30 T 14-10-2018 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 SUPERFAMILY SSF55124 251 426 7.2E-22 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MCR_1130 c80ec4c2c4d9dacd4763d4bda328d07d 558 Gene3D G3DSA:3.30.413.10 119 318 7.9E-78 T 14-10-2018 MCR_1147 ad3d4de3133c12dd7aff87fa1701a1b5 295 Gene3D G3DSA:1.10.8.10 14 93 8.6E-10 T 14-10-2018 MCR_1147 ad3d4de3133c12dd7aff87fa1701a1b5 295 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 12 291 37.985 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MCR_1147 ad3d4de3133c12dd7aff87fa1701a1b5 295 SUPERFAMILY SSF53335 35 275 3.32E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1147 ad3d4de3133c12dd7aff87fa1701a1b5 295 Pfam PF05175 Methyltransferase small domain 129 210 4.5E-17 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MCR_1147 ad3d4de3133c12dd7aff87fa1701a1b5 295 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 39 293 1.7E-70 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MCR_1147 ad3d4de3133c12dd7aff87fa1701a1b5 295 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 38 287 4.9E-77 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MCR_1147 ad3d4de3133c12dd7aff87fa1701a1b5 295 Gene3D G3DSA:3.40.50.150 94 293 2.3E-52 T 14-10-2018 MCR_1147 ad3d4de3133c12dd7aff87fa1701a1b5 295 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 198 204 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MCR_1340 615499d71cf35aa771e6b90855ea522a 280 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 263 1.0E-66 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MCR_1340 615499d71cf35aa771e6b90855ea522a 280 Pfam PF02673 Bacitracin resistance protein BacA 9 266 1.2E-74 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MCR_1340 615499d71cf35aa771e6b90855ea522a 280 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 271 16.914 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MCR_0896 eae064b9bb081a98e01355c66e74c5ee 359 Pfam PF13531 Bacterial extracellular solute-binding protein 59 304 1.1E-37 T 14-10-2018 MCR_0896 eae064b9bb081a98e01355c66e74c5ee 359 SUPERFAMILY SSF53850 50 352 6.6E-69 T 14-10-2018 MCR_0896 eae064b9bb081a98e01355c66e74c5ee 359 Gene3D G3DSA:3.40.190.10 142 351 5.2E-111 T 14-10-2018 MCR_0896 eae064b9bb081a98e01355c66e74c5ee 359 Gene3D G3DSA:3.40.190.10 54 321 5.2E-111 T 14-10-2018 MCR_0896 eae064b9bb081a98e01355c66e74c5ee 359 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 47 352 2.0E-109 T 14-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 MCR_1903 90fed0aa572b85e33246af0914a37c5a 106 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 73 6.6E-22 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor MCR_1903 90fed0aa572b85e33246af0914a37c5a 106 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 2 70 22.083 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor MCR_1903 90fed0aa572b85e33246af0914a37c5a 106 Pfam PF01809 Haemolytic domain 3 69 4.5E-26 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor MCR_1903 90fed0aa572b85e33246af0914a37c5a 106 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 17 67 7.0E-13 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor MCR_1903 90fed0aa572b85e33246af0914a37c5a 106 SMART SM01234 2 69 6.2E-36 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor MCR_0757 428b1b971e100b3036b7d3438d0975bf 83 Gene3D G3DSA:3.10.20.30 5 83 3.2E-18 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MCR_0757 428b1b971e100b3036b7d3438d0975bf 83 SUPERFAMILY SSF54285 7 83 5.23E-17 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MCR_0757 428b1b971e100b3036b7d3438d0975bf 83 Pfam PF02597 ThiS family 9 83 1.2E-14 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MCR_0825 2c48f2a38dc891da88fa14e237ec1985 336 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 75 334 2.5E-66 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MCR_0825 2c48f2a38dc891da88fa14e237ec1985 336 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 79 327 4.0E-16 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MCR_0825 2c48f2a38dc891da88fa14e237ec1985 336 Gene3D G3DSA:3.60.10.10 73 336 1.3E-77 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MCR_0825 2c48f2a38dc891da88fa14e237ec1985 336 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 75 332 1.4E-63 T 14-10-2018 MCR_0825 2c48f2a38dc891da88fa14e237ec1985 336 SUPERFAMILY SSF56219 75 335 4.97E-69 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MCR_0821 8fbf56d75a0f810c6c7875470cfa19ff 323 Pfam PF13177 DNA polymerase III, delta subunit 17 171 1.2E-39 T 14-10-2018 MCR_0821 8fbf56d75a0f810c6c7875470cfa19ff 323 SUPERFAMILY SSF52540 14 207 1.17E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0821 8fbf56d75a0f810c6c7875470cfa19ff 323 Gene3D G3DSA:3.40.50.300 12 170 3.5E-48 T 14-10-2018 MCR_0786 c6b342171f8752645e6eae885d5e5cd0 55 Gene3D G3DSA:1.10.10.10 2 48 2.3E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0786 c6b342171f8752645e6eae885d5e5cd0 55 SUPERFAMILY SSF46785 7 51 3.85E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_1377 75266650509d1095c0d04ca5c185628e 171 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 4 171 29.13 T 14-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 MCR_1377 75266650509d1095c0d04ca5c185628e 171 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 69 171 1.5E-41 T 14-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 MCR_1377 75266650509d1095c0d04ca5c185628e 171 Pfam PF00691 OmpA family 70 165 7.4E-22 T 14-10-2018 IPR006665 OmpA-like domain MCR_1377 75266650509d1095c0d04ca5c185628e 171 ProSitePatterns PS01068 OmpA-like domain. 103 147 - T 14-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 MCR_1377 75266650509d1095c0d04ca5c185628e 171 Gene3D G3DSA:3.30.1330.60 50 171 7.1E-39 T 14-10-2018 IPR036737 OmpA-like domain superfamily MCR_1377 75266650509d1095c0d04ca5c185628e 171 SUPERFAMILY SSF103088 55 169 4.45E-36 T 14-10-2018 IPR036737 OmpA-like domain superfamily MCR_1377 75266650509d1095c0d04ca5c185628e 171 PRINTS PR01021 OMPA domain signature 71 93 6.5E-20 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MCR_1377 75266650509d1095c0d04ca5c185628e 171 PRINTS PR01021 OMPA domain signature 116 132 6.5E-20 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MCR_1377 75266650509d1095c0d04ca5c185628e 171 PRINTS PR01021 OMPA domain signature 101 116 6.5E-20 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MCR_0219 76041bcc9a8703b2fb7c25c2a7bdf408 1000 TIGRFAM TIGR01776 TonB-tbp-lbp: TonB-dependent lactoferrin and transferrin receptors 5 1000 0.0 T 14-10-2018 IPR010948 TonB-dependent lactoferrin/transferrin receptor GO:0015091|GO:0015682|GO:0019867 MCR_0219 76041bcc9a8703b2fb7c25c2a7bdf408 1000 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 64 1000 1.5E-261 T 14-10-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0019867|GO:0022857|GO:0055085 MCR_0219 76041bcc9a8703b2fb7c25c2a7bdf408 1000 SUPERFAMILY SSF56935 85 1000 9.89E-72 T 14-10-2018 MCR_0219 76041bcc9a8703b2fb7c25c2a7bdf408 1000 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 983 1000 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site MCR_0219 76041bcc9a8703b2fb7c25c2a7bdf408 1000 Gene3D G3DSA:2.170.130.10 82 210 3.1E-24 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MCR_0219 76041bcc9a8703b2fb7c25c2a7bdf408 1000 Pfam PF00593 TonB dependent receptor 426 999 2.3E-38 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MCR_0219 76041bcc9a8703b2fb7c25c2a7bdf408 1000 Pfam PF07715 TonB-dependent Receptor Plug Domain 89 194 3.1E-15 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain MCR_1525 e86396bfd61eefd2f9c159034fcc14fd 111 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 3 101 5.6E-26 T 14-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 MCR_1525 e86396bfd61eefd2f9c159034fcc14fd 111 Gene3D G3DSA:3.90.190.10 1 110 5.0E-31 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like MCR_1525 e86396bfd61eefd2f9c159034fcc14fd 111 SUPERFAMILY SSF52799 6 99 1.34E-7 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like MCR_1525 e86396bfd61eefd2f9c159034fcc14fd 111 Pfam PF04273 Putative phosphatase (DUF442) 2 98 4.6E-27 T 14-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 MCR_1737 e502f7f167e65c8d6112db959af57a80 569 Pfam PF00916 Sulfate permease family 23 400 4.0E-86 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MCR_1737 e502f7f167e65c8d6112db959af57a80 569 Pfam PF01740 STAS domain 454 547 3.2E-13 T 14-10-2018 IPR002645 STAS domain MCR_1737 e502f7f167e65c8d6112db959af57a80 569 Gene3D G3DSA:3.30.750.24 433 564 4.4E-22 T 14-10-2018 IPR036513 STAS domain superfamily MCR_1737 e502f7f167e65c8d6112db959af57a80 569 SUPERFAMILY SSF52091 452 562 4.91E-17 T 14-10-2018 IPR036513 STAS domain superfamily MCR_0813 c125d55a23c6be3184f72308238d206b 793 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 700 718 4.2E-7 T 14-10-2018 MCR_0813 c125d55a23c6be3184f72308238d206b 793 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 70 89 4.2E-7 T 14-10-2018 MCR_0813 c125d55a23c6be3184f72308238d206b 793 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 640 659 4.2E-7 T 14-10-2018 MCR_0813 c125d55a23c6be3184f72308238d206b 793 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 670 689 4.2E-7 T 14-10-2018 MCR_0813 c125d55a23c6be3184f72308238d206b 793 Pfam PF13654 AAA domain 39 531 3.3E-153 T 14-10-2018 MCR_0813 c125d55a23c6be3184f72308238d206b 793 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 643 746 8.3E-8 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MCR_0813 c125d55a23c6be3184f72308238d206b 793 Gene3D G3DSA:1.10.8.60 453 528 6.3E-8 T 14-10-2018 MCR_0813 c125d55a23c6be3184f72308238d206b 793 SUPERFAMILY SSF52540 44 530 9.48E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0813 c125d55a23c6be3184f72308238d206b 793 Gene3D G3DSA:3.30.230.10 534 772 2.6E-85 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MCR_0813 c125d55a23c6be3184f72308238d206b 793 Gene3D G3DSA:3.40.50.300 205 443 5.5E-56 T 14-10-2018 MCR_0813 c125d55a23c6be3184f72308238d206b 793 Gene3D G3DSA:3.40.50.300 13 191 2.2E-27 T 14-10-2018 MCR_0813 c125d55a23c6be3184f72308238d206b 793 SUPERFAMILY SSF54211 557 750 1.06E-30 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 15 365 7.9E-101 T 14-10-2018 IPR028053 Membrane insertase YidC, N-terminal MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 Pfam PF02096 60Kd inner membrane protein 367 545 1.4E-58 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR01900 YidC translocation/secretion protein signature 352 368 2.0E-23 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR01900 YidC translocation/secretion protein signature 500 524 2.0E-23 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR01900 YidC translocation/secretion protein signature 481 496 2.0E-23 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 Pfam PF14849 YidC periplasmic domain 82 355 1.3E-76 T 14-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 366 545 3.3E-69 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 14 547 22.769 T 14-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 Gene3D G3DSA:2.70.98.90 78 346 9.0E-92 T 14-10-2018 IPR038221 YidC, periplasmic domain superfamily MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR00701 60kDa inner membrane protein signature 87 108 2.1E-79 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR00701 60kDa inner membrane protein signature 265 280 2.1E-79 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR00701 60kDa inner membrane protein signature 337 357 2.1E-79 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR00701 60kDa inner membrane protein signature 175 195 2.1E-79 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR00701 60kDa inner membrane protein signature 475 497 2.1E-79 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR00701 60kDa inner membrane protein signature 428 451 2.1E-79 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR00701 60kDa inner membrane protein signature 511 534 2.1E-79 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR00701 60kDa inner membrane protein signature 233 251 2.1E-79 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_1902 a23cb5665fb80777de6e7f9a1d6f5d07 556 PRINTS PR00701 60kDa inner membrane protein signature 12 33 2.1E-79 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MCR_0494 336e20d1df5e217ce60462085ef863a1 189 SMART SM00671 83 118 4.0E-9 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0494 336e20d1df5e217ce60462085ef863a1 189 SMART SM00671 47 82 1.5E-5 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0494 336e20d1df5e217ce60462085ef863a1 189 SUPERFAMILY SSF81901 42 149 8.5E-25 T 14-10-2018 MCR_0494 336e20d1df5e217ce60462085ef863a1 189 Gene3D G3DSA:1.25.40.10 31 188 7.5E-36 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0494 336e20d1df5e217ce60462085ef863a1 189 Pfam PF08238 Sel1 repeat 138 149 170.0 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0494 336e20d1df5e217ce60462085ef863a1 189 Pfam PF08238 Sel1 repeat 83 118 3.1E-8 T 14-10-2018 IPR006597 Sel1-like repeat MCR_0494 336e20d1df5e217ce60462085ef863a1 189 Pfam PF08238 Sel1 repeat 48 80 2.4E-8 T 14-10-2018 IPR006597 Sel1-like repeat MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 414 459 5.7E-8 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 164 266 3.0E-18 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 Gene3D G3DSA:3.40.120.10 263 381 7.8E-34 T 14-10-2018 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 SUPERFAMILY SSF53738 270 377 7.06E-30 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 Gene3D G3DSA:3.40.120.10 9 161 2.7E-45 T 14-10-2018 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 14 142 1.8E-32 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 8.4E-29 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 246 261 8.4E-29 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 104 118 8.4E-29 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 217 230 8.4E-29 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 SUPERFAMILY SSF55957 381 466 2.96E-17 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 271 380 6.8E-21 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 Gene3D G3DSA:3.40.120.10 182 262 1.8E-25 T 14-10-2018 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 105 114 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 SUPERFAMILY SSF53738 9 186 3.53E-37 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 SUPERFAMILY SSF53738 164 269 5.89E-25 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MCR_1842 43b8d454ecee52a52b62af7cab2735f1 474 Gene3D G3DSA:3.30.310.50 382 465 2.0E-21 T 14-10-2018 MCR_0891 cd4f18ef852e9c39fbe9ae13f7930686 143 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 11 120 1.1E-8 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MCR_0891 cd4f18ef852e9c39fbe9ae13f7930686 143 Gene3D G3DSA:3.30.70.560 8 141 2.8E-10 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MCR_0891 cd4f18ef852e9c39fbe9ae13f7930686 143 SUPERFAMILY SSF55083 9 109 1.29E-10 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MCR_1666 6d6552b5969f9efcd9b6ea4b533098af 269 Gene3D G3DSA:1.10.287.460 36 139 3.5E-26 T 14-10-2018 IPR036944 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily GO:0006457 MCR_1666 6d6552b5969f9efcd9b6ea4b533098af 269 SUPERFAMILY SSF54534 45 241 1.63E-49 T 14-10-2018 MCR_1666 6d6552b5969f9efcd9b6ea4b533098af 269 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 153 238 4.8E-21 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MCR_1666 6d6552b5969f9efcd9b6ea4b533098af 269 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 39 145 1.4E-28 T 14-10-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 MCR_1666 6d6552b5969f9efcd9b6ea4b533098af 269 Gene3D G3DSA:3.10.50.40 140 244 2.2E-34 T 14-10-2018 MCR_0440 af18f78bd01926e840df481bb9971010 644 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 643 30.601 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 MCR_0440 af18f78bd01926e840df481bb9971010 644 Gene3D G3DSA:3.40.50.11260 421 508 2.5E-29 T 14-10-2018 MCR_0440 af18f78bd01926e840df481bb9971010 644 SUPERFAMILY SSF55874 7 222 4.19E-60 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0440 af18f78bd01926e840df481bb9971010 644 PRINTS PR00775 90kDa heat shock protein signature 93 110 2.9E-50 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MCR_0440 af18f78bd01926e840df481bb9971010 644 PRINTS PR00775 90kDa heat shock protein signature 197 215 2.9E-50 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MCR_0440 af18f78bd01926e840df481bb9971010 644 PRINTS PR00775 90kDa heat shock protein signature 120 142 2.9E-50 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MCR_0440 af18f78bd01926e840df481bb9971010 644 PRINTS PR00775 90kDa heat shock protein signature 26 48 2.9E-50 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MCR_0440 af18f78bd01926e840df481bb9971010 644 PRINTS PR00775 90kDa heat shock protein signature 75 92 2.9E-50 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MCR_0440 af18f78bd01926e840df481bb9971010 644 PRINTS PR00775 90kDa heat shock protein signature 5 25 2.9E-50 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MCR_0440 af18f78bd01926e840df481bb9971010 644 SUPERFAMILY SSF110942 533 643 7.85E-36 T 14-10-2018 IPR037196 HSP90, C-terminal domain MCR_0440 af18f78bd01926e840df481bb9971010 644 PIRSF PIRSF002583 1 644 1.5E-205 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 MCR_0440 af18f78bd01926e840df481bb9971010 644 Gene3D G3DSA:1.20.120.790 514 643 4.8E-44 T 14-10-2018 IPR037196 HSP90, C-terminal domain MCR_0440 af18f78bd01926e840df481bb9971010 644 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 183 6.0E-12 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MCR_0440 af18f78bd01926e840df481bb9971010 644 Gene3D G3DSA:3.30.565.10 2 221 1.4E-71 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MCR_0440 af18f78bd01926e840df481bb9971010 644 Gene3D G3DSA:3.30.230.80 248 420 7.3E-64 T 14-10-2018 MCR_0440 af18f78bd01926e840df481bb9971010 644 Pfam PF00183 Hsp90 protein 231 642 3.9E-124 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 MCR_0440 af18f78bd01926e840df481bb9971010 644 SUPERFAMILY SSF54211 250 507 2.2E-89 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 11 22 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 Gene3D G3DSA:1.10.287.610 108 155 2.6E-89 T 14-10-2018 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 7 230 40.56 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 163 187 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 SUPERFAMILY SSF52313 11 234 4.32E-91 T 14-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 9 231 1.6E-101 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 Gene3D G3DSA:3.40.50.10490 14 224 2.6E-89 T 14-10-2018 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 PRINTS PR00395 Ribosomal protein S2 signature 163 180 1.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 PRINTS PR00395 Ribosomal protein S2 signature 42 51 1.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 PRINTS PR00395 Ribosomal protein S2 signature 180 191 1.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 PRINTS PR00395 Ribosomal protein S2 signature 201 215 1.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 PRINTS PR00395 Ribosomal protein S2 signature 11 29 1.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 PRINTS PR00395 Ribosomal protein S2 signature 92 109 1.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0276 2867ad5c66f0f7d5c1949bc5cf50ca32 271 Pfam PF00318 Ribosomal protein S2 14 229 3.8E-93 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1696 442ab939c4de7b817eaa9e6bd04dde42 453 SUPERFAMILY SSF51161 251 433 3.06E-49 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MCR_1696 442ab939c4de7b817eaa9e6bd04dde42 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 314 345 1.6E-6 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_1696 442ab939c4de7b817eaa9e6bd04dde42 453 SUPERFAMILY SSF53448 1 248 2.33E-57 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1696 442ab939c4de7b817eaa9e6bd04dde42 453 Pfam PF12804 MobA-like NTP transferase domain 6 119 1.9E-18 T 14-10-2018 IPR025877 MobA-like NTP transferase MCR_1696 442ab939c4de7b817eaa9e6bd04dde42 453 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 391 425 6.9E-9 T 14-10-2018 IPR001451 Hexapeptide repeat MCR_1696 442ab939c4de7b817eaa9e6bd04dde42 453 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 450 1.8E-175 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 MCR_1696 442ab939c4de7b817eaa9e6bd04dde42 453 Gene3D G3DSA:3.90.550.10 1 223 5.0E-59 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1696 442ab939c4de7b817eaa9e6bd04dde42 453 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 448 39.487 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 MCR_1696 442ab939c4de7b817eaa9e6bd04dde42 453 Gene3D G3DSA:2.160.10.10 224 452 2.5E-63 T 14-10-2018 MCR_0656 e3902b97c3bf89cfe8e669dff63853bc 195 Pfam PF00929 Exonuclease 21 182 7.0E-34 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MCR_0656 e3902b97c3bf89cfe8e669dff63853bc 195 Hamap MF_00045 Oligoribonuclease [orn]. 15 193 41.828 T 14-10-2018 IPR022894 Oligoribonuclease GO:0000175 MCR_0656 e3902b97c3bf89cfe8e669dff63853bc 195 SMART SM00479 19 192 1.9E-23 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MCR_0656 e3902b97c3bf89cfe8e669dff63853bc 195 Gene3D G3DSA:3.30.420.10 6 193 6.3E-72 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MCR_0656 e3902b97c3bf89cfe8e669dff63853bc 195 SUPERFAMILY SSF53098 19 192 1.52E-46 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MCR_0448 3b618224046cef03127b9f5f606fec45 498 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 9 465 4.9E-113 T 14-10-2018 IPR003846 Uncharacterised protein family UPF0061 MCR_1839 f17c15fe06c19c6158b1c99ccc516c33 309 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 304 3.2E-139 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MCR_1839 f17c15fe06c19c6158b1c99ccc516c33 309 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MCR_1839 f17c15fe06c19c6158b1c99ccc516c33 309 Gene3D G3DSA:3.40.50.1100 6 300 1.9E-125 T 14-10-2018 MCR_1839 f17c15fe06c19c6158b1c99ccc516c33 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 291 2.3E-68 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MCR_1839 f17c15fe06c19c6158b1c99ccc516c33 309 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 304 4.0E-145 T 14-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MCR_1839 f17c15fe06c19c6158b1c99ccc516c33 309 Gene3D G3DSA:3.40.50.1100 45 143 1.9E-125 T 14-10-2018 MCR_1839 f17c15fe06c19c6158b1c99ccc516c33 309 SUPERFAMILY SSF53686 2 305 4.58E-103 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MCR_1839 f17c15fe06c19c6158b1c99ccc516c33 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 178 2.9E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1839 f17c15fe06c19c6158b1c99ccc516c33 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 129 2.9E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1839 f17c15fe06c19c6158b1c99ccc516c33 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 253 269 2.9E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0833 524bc30563ce14599c771ddba8201ff1 214 Gene3D G3DSA:3.40.50.1820 1 213 3.3E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0833 524bc30563ce14599c771ddba8201ff1 214 Pfam PF00561 alpha/beta hydrolase fold 60 125 5.4E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MCR_0833 524bc30563ce14599c771ddba8201ff1 214 SUPERFAMILY SSF53474 4 200 1.16E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_1852 1ac3fc75c5ed107831a5f02f6d7ee3c4 568 Gene3D G3DSA:3.40.50.300 1 268 5.6E-43 T 14-10-2018 MCR_1852 1ac3fc75c5ed107831a5f02f6d7ee3c4 568 Gene3D G3DSA:3.40.50.300 269 554 1.1E-38 T 14-10-2018 MCR_1852 1ac3fc75c5ed107831a5f02f6d7ee3c4 568 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 553 3.1E-127 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MCR_1852 1ac3fc75c5ed107831a5f02f6d7ee3c4 568 Pfam PF02463 RecF/RecN/SMC N terminal domain 14 514 4.7E-24 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal MCR_1852 1ac3fc75c5ed107831a5f02f6d7ee3c4 568 PIRSF PIRSF003128 1 558 3.0E-129 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MCR_1852 1ac3fc75c5ed107831a5f02f6d7ee3c4 568 SUPERFAMILY SSF52540 1 515 1.39E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1486 dcce005b40839af714eceba238891eb9 330 SUPERFAMILY SSF47823 26 120 1.14E-9 T 14-10-2018 MCR_1486 dcce005b40839af714eceba238891eb9 330 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 29 112 9.9E-12 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MCR_1486 dcce005b40839af714eceba238891eb9 330 Pfam PF00589 Phage integrase family 153 307 1.2E-41 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MCR_1486 dcce005b40839af714eceba238891eb9 330 SUPERFAMILY SSF56349 129 320 8.54E-49 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MCR_1486 dcce005b40839af714eceba238891eb9 330 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 25 322 48.137 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD MCR_1486 dcce005b40839af714eceba238891eb9 330 Gene3D G3DSA:1.10.150.130 25 120 1.0E-15 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal MCR_1486 dcce005b40839af714eceba238891eb9 330 Gene3D G3DSA:1.10.443.10 136 316 8.2E-55 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MCR_0391 50c0e67286bee3eb9d968d95b2cd6cb4 123 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 5 116 30.162 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0391 50c0e67286bee3eb9d968d95b2cd6cb4 123 SUPERFAMILY SSF50104 8 117 1.1E-44 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily MCR_0391 50c0e67286bee3eb9d968d95b2cd6cb4 123 Gene3D G3DSA:2.30.30.790 12 120 1.8E-17 T 14-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0391 50c0e67286bee3eb9d968d95b2cd6cb4 123 Pfam PF01245 Ribosomal protein L19 7 115 2.1E-48 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0391 50c0e67286bee3eb9d968d95b2cd6cb4 123 ProSitePatterns PS01015 Ribosomal protein L19 signature. 88 103 - T 14-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0391 50c0e67286bee3eb9d968d95b2cd6cb4 123 PIRSF PIRSF002191 2 123 2.1E-50 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0391 50c0e67286bee3eb9d968d95b2cd6cb4 123 PRINTS PR00061 Ribosomal protein L19 signature 36 65 7.3E-34 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0391 50c0e67286bee3eb9d968d95b2cd6cb4 123 PRINTS PR00061 Ribosomal protein L19 signature 6 35 7.3E-34 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0391 50c0e67286bee3eb9d968d95b2cd6cb4 123 PRINTS PR00061 Ribosomal protein L19 signature 90 115 7.3E-34 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0391 50c0e67286bee3eb9d968d95b2cd6cb4 123 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 7 115 2.3E-48 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1453 8ca78cf391b83ce48e903846aa5a0051 146 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 2 145 1.9E-53 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MCR_1453 8ca78cf391b83ce48e903846aa5a0051 146 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 58 142 2.0E-35 T 14-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 MCR_1453 8ca78cf391b83ce48e903846aa5a0051 146 Gene3D G3DSA:3.10.20.80 1 50 7.5E-19 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MCR_1453 8ca78cf391b83ce48e903846aa5a0051 146 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 51 1.0E-18 T 14-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MCR_1453 8ca78cf391b83ce48e903846aa5a0051 146 SUPERFAMILY SSF54364 1 53 6.8E-18 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MCR_1453 8ca78cf391b83ce48e903846aa5a0051 146 SUPERFAMILY SSF55200 58 146 9.29E-32 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 MCR_1453 8ca78cf391b83ce48e903846aa5a0051 146 Gene3D G3DSA:3.30.110.10 51 146 1.7E-35 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 192 2.9E-77 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 SUPERFAMILY SSF52317 1 193 3.48E-54 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 4.1E-13 T 14-10-2018 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 4.1E-13 T 14-10-2018 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 4.1E-13 T 14-10-2018 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 Gene3D G3DSA:3.40.50.880 1 194 1.1E-61 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 8.8E-6 T 14-10-2018 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 8.8E-6 T 14-10-2018 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.4E-32 T 14-10-2018 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.4E-32 T 14-10-2018 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.4E-32 T 14-10-2018 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.4E-32 T 14-10-2018 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.4E-32 T 14-10-2018 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 PRINTS PR00097 Anthranilate synthase component II signature 169 182 1.4E-32 T 14-10-2018 MCR_0853 3cc313c8c4a37dae6fab708843a1e319 207 Pfam PF00117 Glutamine amidotransferase class-I 4 191 5.0E-50 T 14-10-2018 IPR017926 Glutamine amidotransferase MCR_1024 773027981540eb98d95d1f2fdb9d6aee 216 SUPERFAMILY SSF52016 1 201 5.69E-63 T 14-10-2018 MCR_1024 773027981540eb98d95d1f2fdb9d6aee 216 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 43.098 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MCR_1024 773027981540eb98d95d1f2fdb9d6aee 216 Pfam PF00694 Aconitase C-terminal domain 1 131 1.5E-38 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MCR_1024 773027981540eb98d95d1f2fdb9d6aee 216 Gene3D G3DSA:3.20.19.10 1 188 7.1E-76 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MCR_1024 773027981540eb98d95d1f2fdb9d6aee 216 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 4.8E-85 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MCR_0350 16cfac2507757405b2c8382e6bb7a3be 728 Gene3D G3DSA:1.10.3210.10 18 207 8.4E-62 T 14-10-2018 MCR_0350 16cfac2507757405b2c8382e6bb7a3be 728 Pfam PF13328 HD domain 43 187 1.1E-38 T 14-10-2018 IPR003607 HD/PDEase domain MCR_0350 16cfac2507757405b2c8382e6bb7a3be 728 Gene3D G3DSA:3.10.20.30 395 468 6.5E-18 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MCR_0350 16cfac2507757405b2c8382e6bb7a3be 728 SUPERFAMILY SSF81271 395 459 8.5E-11 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MCR_0350 16cfac2507757405b2c8382e6bb7a3be 728 Pfam PF02824 TGS domain 402 457 1.2E-10 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MCR_0350 16cfac2507757405b2c8382e6bb7a3be 728 SMART SM00471 58 169 5.8E-9 T 14-10-2018 IPR003607 HD/PDEase domain MCR_0350 16cfac2507757405b2c8382e6bb7a3be 728 SUPERFAMILY SSF109604 25 206 5.65E-55 T 14-10-2018 MCR_0350 16cfac2507757405b2c8382e6bb7a3be 728 SUPERFAMILY SSF81301 208 364 4.58E-15 T 14-10-2018 MCR_0918 32573491230e3d6152069fad40dbc3c9 470 Gene3D G3DSA:3.30.830.10 39 260 5.0E-74 T 14-10-2018 MCR_0918 32573491230e3d6152069fad40dbc3c9 470 SUPERFAMILY SSF63411 279 462 6.67E-30 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MCR_0918 32573491230e3d6152069fad40dbc3c9 470 Pfam PF05193 Peptidase M16 inactive domain 209 393 4.3E-28 T 14-10-2018 IPR007863 Peptidase M16, C-terminal MCR_0918 32573491230e3d6152069fad40dbc3c9 470 SUPERFAMILY SSF63411 42 248 1.3E-61 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MCR_0918 32573491230e3d6152069fad40dbc3c9 470 Pfam PF00675 Insulinase (Peptidase family M16) 54 200 2.4E-25 T 14-10-2018 IPR011765 Peptidase M16, N-terminal MCR_0918 32573491230e3d6152069fad40dbc3c9 470 Gene3D G3DSA:3.30.830.10 264 460 2.1E-41 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 Gene3D G3DSA:3.50.50.60 14 313 5.7E-86 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 145 2.3E-27 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 2.3E-27 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 301 2.3E-27 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 2.3E-27 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.3E-27 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 336 441 1.3E-29 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 Gene3D G3DSA:3.50.50.60 139 257 5.7E-86 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PIRSF PIRSF000350 1 446 6.7E-93 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 SUPERFAMILY SSF55424 334 443 7.73E-33 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 306 3.5E-59 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 Gene3D G3DSA:3.30.390.30 332 447 3.6E-33 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 395 410 2.9E-51 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 60 2.9E-51 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 330 351 2.9E-51 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 437 2.9E-51 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 2.9E-51 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 2.9E-51 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 294 301 2.9E-51 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 2.9E-51 T 14-10-2018 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 46 56 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MCR_1658 0640ffadc06f62b33947fb1971d63804 447 SUPERFAMILY SSF51905 9 358 3.56E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0787 f02cb5d22381f9b5886fef042d71b578 498 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 44 490 3.0E-206 T 14-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 MCR_0787 f02cb5d22381f9b5886fef042d71b578 498 Gene3D G3DSA:3.40.309.10 275 464 3.6E-185 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MCR_0787 f02cb5d22381f9b5886fef042d71b578 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 296 307 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MCR_0787 f02cb5d22381f9b5886fef042d71b578 498 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 268 275 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MCR_0787 f02cb5d22381f9b5886fef042d71b578 498 Gene3D G3DSA:3.40.605.10 33 486 3.6E-185 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MCR_0787 f02cb5d22381f9b5886fef042d71b578 498 SUPERFAMILY SSF53720 22 495 2.49E-172 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MCR_0787 f02cb5d22381f9b5886fef042d71b578 498 Pfam PF00171 Aldehyde dehydrogenase family 33 490 8.6E-174 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MCR_0755 56d6079f013fccf3a65b7ee49cb37e94 141 SUPERFAMILY SSF50331 1 70 1.21E-19 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MCR_0755 56d6079f013fccf3a65b7ee49cb37e94 141 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 69 7.5E-22 T 14-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 MCR_0755 56d6079f013fccf3a65b7ee49cb37e94 141 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 74 139 1.9E-19 T 14-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 MCR_0755 56d6079f013fccf3a65b7ee49cb37e94 141 Pfam PF03459 TOBE domain 4 66 1.8E-13 T 14-10-2018 IPR005116 Transport-associated OB, type 1 MCR_0755 56d6079f013fccf3a65b7ee49cb37e94 141 Pfam PF03459 TOBE domain 75 135 8.3E-15 T 14-10-2018 IPR005116 Transport-associated OB, type 1 MCR_0755 56d6079f013fccf3a65b7ee49cb37e94 141 Gene3D G3DSA:2.40.50.100 69 141 2.7E-24 T 14-10-2018 MCR_0755 56d6079f013fccf3a65b7ee49cb37e94 141 SUPERFAMILY SSF50331 74 139 2.08E-19 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MCR_0755 56d6079f013fccf3a65b7ee49cb37e94 141 Gene3D G3DSA:2.40.50.100 1 67 5.7E-24 T 14-10-2018 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 SUPERFAMILY SSF52954 477 570 1.16E-25 T 14-10-2018 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 Pfam PF03129 Anticodon binding domain 483 570 1.5E-19 T 14-10-2018 IPR004154 Anticodon-binding MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.1E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.1E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.1E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.1E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 Gene3D G3DSA:3.40.50.800 4 560 1.2E-225 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 572 39.998 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 SUPERFAMILY SSF55681 10 469 5.17E-97 T 14-10-2018 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 569 2.1E-233 T 14-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 Pfam PF04073 Aminoacyl-tRNA editing domain 256 377 3.8E-19 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 460 4.7E-48 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 Gene3D G3DSA:3.30.930.10 11 466 1.2E-225 T 14-10-2018 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 SUPERFAMILY SSF55826 218 391 3.53E-23 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MCR_1429 b972b6ae0e7668dfa978ca0edc8d8ffe 572 Gene3D G3DSA:3.90.960.10 240 390 1.2E-225 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MCR_1725 1cbd176e72eb1da5b57795ab8384b718 248 SUPERFAMILY SSF53649 2 234 5.09E-40 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MCR_1725 1cbd176e72eb1da5b57795ab8384b718 248 Gene3D G3DSA:3.40.720.10 1 246 6.8E-32 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MCR_1725 1cbd176e72eb1da5b57795ab8384b718 248 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 1 188 5.5E-18 T 14-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 Gene3D G3DSA:3.40.30.10 57 199 2.2E-25 T 14-10-2018 MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 SUPERFAMILY SSF51316 412 551 5.75E-55 T 14-10-2018 IPR011057 Mss4-like superfamily MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 Pfam PF08534 Redoxin 72 179 5.0E-10 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 414 546 3.5E-59 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 Gene3D G3DSA:3.30.1060.10 223 392 2.8E-62 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 414 538 34.717 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 225 383 36.341 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 SUPERFAMILY SSF52833 67 183 2.9E-20 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 Pfam PF01641 SelR domain 418 537 7.0E-44 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 Gene3D G3DSA:2.170.150.20 408 555 7.8E-54 T 14-10-2018 MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 Pfam PF01625 Peptide methionine sulfoxide reductase 227 378 1.0E-58 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 SUPERFAMILY SSF55068 222 381 7.46E-63 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MCR_0686 1a79c5b4dc9c647526b6ac541dcdc3ac 558 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 226 377 2.4E-52 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MCR_0872 7a05b231f9fd2f3c93c1a56435b83342 232 Gene3D G3DSA:3.40.50.620 4 231 3.0E-73 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0872 7a05b231f9fd2f3c93c1a56435b83342 232 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 7 216 6.9E-64 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MCR_0872 7a05b231f9fd2f3c93c1a56435b83342 232 Pfam PF06508 Queuosine biosynthesis protein QueC 7 222 4.8E-77 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MCR_0872 7a05b231f9fd2f3c93c1a56435b83342 232 SUPERFAMILY SSF52402 5 231 5.29E-62 T 14-10-2018 MCR_0872 7a05b231f9fd2f3c93c1a56435b83342 232 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 5 229 52.342 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MCR_0872 7a05b231f9fd2f3c93c1a56435b83342 232 PIRSF PIRSF006293 3 232 1.3E-77 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MCR_0572 db5cf2474b5c071398e89f9b12bc11b9 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 14-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0572 db5cf2474b5c071398e89f9b12bc11b9 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 5.2E-39 T 14-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0572 db5cf2474b5c071398e89f9b12bc11b9 103 SUPERFAMILY SSF141091 1 102 1.1E-36 T 14-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0572 db5cf2474b5c071398e89f9b12bc11b9 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 3.5E-39 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0572 db5cf2474b5c071398e89f9b12bc11b9 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 26.383 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1110 f9876f9e1026e7451851dc40848a0894 239 Gene3D G3DSA:3.90.550.10 4 239 9.7E-53 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1110 f9876f9e1026e7451851dc40848a0894 239 Pfam PF00483 Nucleotidyl transferase 5 157 6.8E-22 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MCR_1110 f9876f9e1026e7451851dc40848a0894 239 SUPERFAMILY SSF53448 4 234 1.58E-45 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1900 2baa9a86842750fa5eeb6b4590cb955e 156 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 1.5E-59 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MCR_1900 2baa9a86842750fa5eeb6b4590cb955e 156 Pfam PF03477 ATP cone domain 50 136 7.4E-16 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MCR_1900 2baa9a86842750fa5eeb6b4590cb955e 156 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 154 79.834 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 SUPERFAMILY SSF63411 519 777 5.39E-52 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 Gene3D G3DSA:3.30.830.10 527 796 2.0E-109 T 14-10-2018 MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 Pfam PF05193 Peptidase M16 inactive domain 199 387 1.5E-13 T 14-10-2018 IPR007863 Peptidase M16, C-terminal MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 Gene3D G3DSA:3.30.830.10 259 484 4.6E-51 T 14-10-2018 MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 SUPERFAMILY SSF63411 8 237 3.0E-41 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 Pfam PF00675 Insulinase (Peptidase family M16) 54 147 1.7E-6 T 14-10-2018 IPR011765 Peptidase M16, N-terminal MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 Pfam PF08367 Peptidase M16C associated 463 714 4.8E-54 T 14-10-2018 IPR013578 Peptidase M16C associated GO:0006508 Reactome: R-HSA-1268020 MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 SUPERFAMILY SSF63411 799 971 2.97E-39 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 SUPERFAMILY SSF63411 259 520 3.45E-51 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 Gene3D G3DSA:3.30.830.10 1 248 6.2E-81 T 14-10-2018 MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 SMART SM01264 463 716 5.4E-73 T 14-10-2018 IPR013578 Peptidase M16C associated GO:0006508 Reactome: R-HSA-1268020 MCR_1652 8d35c3dfecc07a208902aaac81f763cf 989 Gene3D G3DSA:3.30.830.10 498 960 2.0E-109 T 14-10-2018 MCR_1259 22261ae1b7b7f5016add242f41f41868 418 Gene3D G3DSA:3.30.9.50 87 291 1.6E-86 T 14-10-2018 MCR_1259 22261ae1b7b7f5016add242f41f41868 418 Gene3D G3DSA:3.50.50.60 8 363 1.6E-86 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1259 22261ae1b7b7f5016add242f41f41868 418 Pfam PF01494 FAD binding domain 8 354 3.8E-36 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 MCR_1259 22261ae1b7b7f5016add242f41f41868 418 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 8 415 5.8E-96 T 14-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MCR_1259 22261ae1b7b7f5016add242f41f41868 418 SUPERFAMILY SSF51905 8 407 1.18E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_1259 22261ae1b7b7f5016add242f41f41868 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 317 333 1.7E-21 T 14-10-2018 MCR_1259 22261ae1b7b7f5016add242f41f41868 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.7E-21 T 14-10-2018 MCR_1259 22261ae1b7b7f5016add242f41f41868 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 317 1.7E-21 T 14-10-2018 MCR_1259 22261ae1b7b7f5016add242f41f41868 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 167 182 1.7E-21 T 14-10-2018 MCR_0744 977a62474716bdb48b6556132c33e334 258 Gene3D G3DSA:2.60.120.10 24 177 2.3E-7 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MCR_0744 977a62474716bdb48b6556132c33e334 258 SUPERFAMILY SSF51206 11 154 8.04E-11 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like MCR_0744 977a62474716bdb48b6556132c33e334 258 SUPERFAMILY SSF46785 186 257 6.82E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0744 977a62474716bdb48b6556132c33e334 258 SMART SM00419 200 248 2.7E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MCR_0744 977a62474716bdb48b6556132c33e334 258 Pfam PF13545 Crp-like helix-turn-helix domain 189 254 6.4E-12 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MCR_0744 977a62474716bdb48b6556132c33e334 258 Gene3D G3DSA:1.10.10.10 180 255 1.3E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_1155 0dd4895e288ef5d9964d5831ce0aaf9d 368 PIRSF PIRSF001456 3 365 1.3E-134 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MCR_1155 0dd4895e288ef5d9964d5831ce0aaf9d 368 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MCR_1155 0dd4895e288ef5d9964d5831ce0aaf9d 368 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MCR_1155 0dd4895e288ef5d9964d5831ce0aaf9d 368 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 35.828 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MCR_1155 0dd4895e288ef5d9964d5831ce0aaf9d 368 Pfam PF01264 Chorismate synthase 10 345 4.0E-135 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MCR_1155 0dd4895e288ef5d9964d5831ce0aaf9d 368 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 6.7E-132 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MCR_1155 0dd4895e288ef5d9964d5831ce0aaf9d 368 SUPERFAMILY SSF103263 4 351 1.15E-142 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MCR_1155 0dd4895e288ef5d9964d5831ce0aaf9d 368 Gene3D G3DSA:3.60.150.10 1 363 2.5E-155 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MCR_1155 0dd4895e288ef5d9964d5831ce0aaf9d 368 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MCR_0495 34a96a97b5e3413d395aff69cedbfbdb 204 SUPERFAMILY SSF53335 6 181 2.07E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0495 34a96a97b5e3413d395aff69cedbfbdb 204 Gene3D G3DSA:3.40.50.150 2 170 2.3E-27 T 14-10-2018 MCR_0495 34a96a97b5e3413d395aff69cedbfbdb 204 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 2 201 3.6E-74 T 14-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 MCR_0495 34a96a97b5e3413d395aff69cedbfbdb 204 Pfam PF07021 Methionine biosynthesis protein MetW 2 201 6.2E-73 T 14-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 MCR_0581 aed7e2c0cda5645aafb0b9e8f993fbe8 78 Gene3D G3DSA:2.30.170.40 2 78 4.8E-34 T 14-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0581 aed7e2c0cda5645aafb0b9e8f993fbe8 78 Pfam PF00830 Ribosomal L28 family 3 61 6.3E-28 T 14-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0581 aed7e2c0cda5645aafb0b9e8f993fbe8 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 22.496 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0581 aed7e2c0cda5645aafb0b9e8f993fbe8 78 SUPERFAMILY SSF143800 2 77 3.14E-31 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0581 aed7e2c0cda5645aafb0b9e8f993fbe8 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 2.1E-29 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0181 ab4e2212b7f6c19910f88d40d25d9448 315 Gene3D G3DSA:2.40.30.170 146 220 6.0E-11 T 14-10-2018 MCR_0181 ab4e2212b7f6c19910f88d40d25d9448 315 Gene3D G3DSA:2.40.50.100 109 145 6.0E-11 T 14-10-2018 MCR_0181 ab4e2212b7f6c19910f88d40d25d9448 315 Gene3D G3DSA:2.40.420.20 221 301 6.0E-11 T 14-10-2018 MCR_0181 ab4e2212b7f6c19910f88d40d25d9448 315 SUPERFAMILY SSF51230 75 140 1.93E-5 T 14-10-2018 IPR011053 Single hybrid motif MCR_1785 829a295353419327a7ef42384ac88ea8 164 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 24 160 2.4E-53 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_1785 829a295353419327a7ef42384ac88ea8 164 SUPERFAMILY SSF52121 20 164 1.06E-56 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_1785 829a295353419327a7ef42384ac88ea8 164 Gene3D G3DSA:3.40.50.960 11 164 2.2E-58 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_1785 829a295353419327a7ef42384ac88ea8 164 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 24 161 1.3E-54 T 14-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_1785 829a295353419327a7ef42384ac88ea8 164 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 19 164 30.635 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 Gene3D G3DSA:3.30.540.10 1 184 1.8E-58 T 14-10-2018 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 PIRSF PIRSF500210 1 324 1.6E-111 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 6 180 3.4E-52 T 14-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 SUPERFAMILY SSF56655 5 320 6.62E-100 T 14-10-2018 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 PIRSF PIRSF000904 1 324 1.5E-109 T 14-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 296 321 1.4E-50 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 194 221 1.4E-50 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 21 48 1.4E-50 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 58 84 1.4E-50 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 137 160 1.4E-50 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 168 191 1.4E-50 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 Gene3D G3DSA:3.40.190.80 185 323 1.1E-49 T 14-10-2018 MCR_0403 e23a755d3f2a82b372fd5911e4cc0f3b 332 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 2 322 42.673 T 14-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MCR_0273 ce5ed48eab9210c6ff50b1167ae33c74 165 Gene3D G3DSA:3.90.79.10 1 157 7.8E-41 T 14-10-2018 MCR_0273 ce5ed48eab9210c6ff50b1167ae33c74 165 Pfam PF00293 NUDIX domain 7 145 3.3E-23 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MCR_0273 ce5ed48eab9210c6ff50b1167ae33c74 165 SUPERFAMILY SSF55811 6 155 9.07E-30 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MCR_0273 ce5ed48eab9210c6ff50b1167ae33c74 165 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 34.618 T 14-10-2018 IPR022927 RNA pyrophosphohydrolase RppH MCR_0273 ce5ed48eab9210c6ff50b1167ae33c74 165 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MCR_0273 ce5ed48eab9210c6ff50b1167ae33c74 165 PRINTS PR00502 NUDIX hydrolase family signature 33 47 2.1E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MCR_0273 ce5ed48eab9210c6ff50b1167ae33c74 165 PRINTS PR00502 NUDIX hydrolase family signature 47 62 2.1E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MCR_1050 c37d335f567685ad2d988806151523c1 255 SUPERFAMILY SSF102705 5 254 7.98E-74 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily MCR_1050 c37d335f567685ad2d988806151523c1 255 Gene3D G3DSA:3.40.1390.30 100 226 3.0E-76 T 14-10-2018 MCR_1050 c37d335f567685ad2d988806151523c1 255 Gene3D G3DSA:3.40.1390.30 17 241 3.0E-76 T 14-10-2018 MCR_1050 c37d335f567685ad2d988806151523c1 255 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 254 8.0E-59 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MCR_1050 c37d335f567685ad2d988806151523c1 255 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 242 4.8E-57 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MCR_0745 05f96f40613cf862aca769c09c3ba124 210 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 43 50 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MCR_0745 05f96f40613cf862aca769c09c3ba124 210 Pfam PF00484 Carbonic anhydrase 38 188 9.2E-51 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MCR_0745 05f96f40613cf862aca769c09c3ba124 210 SMART SM00947 31 193 6.8E-67 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MCR_0745 05f96f40613cf862aca769c09c3ba124 210 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 83 103 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MCR_0745 05f96f40613cf862aca769c09c3ba124 210 Gene3D G3DSA:3.40.1050.10 1 209 4.8E-81 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MCR_0745 05f96f40613cf862aca769c09c3ba124 210 SUPERFAMILY SSF53056 5 202 1.57E-71 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MCR_0838 19d8c41b8ca2b58a98e947373a33d6f7 180 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 62 172 1.3E-29 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MCR_0838 19d8c41b8ca2b58a98e947373a33d6f7 180 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 21 175 20.775 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MCR_0838 19d8c41b8ca2b58a98e947373a33d6f7 180 Gene3D G3DSA:3.40.390.30 21 180 1.7E-37 T 14-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 MCR_0838 19d8c41b8ca2b58a98e947373a33d6f7 180 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 140 150 - T 14-10-2018 IPR020549 Endoribonuclease YbeY, conserved site MCR_0838 19d8c41b8ca2b58a98e947373a33d6f7 180 SUPERFAMILY SSF55486 52 178 3.81E-36 T 14-10-2018 MCR_0838 19d8c41b8ca2b58a98e947373a33d6f7 180 Pfam PF02130 Uncharacterized protein family UPF0054 57 171 1.3E-28 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MCR_1669 2945b1e12f074eee2a8c0388bde4779b 86 SUPERFAMILY SSF55729 1 83 2.09E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MCR_1669 2945b1e12f074eee2a8c0388bde4779b 86 Pfam PF14542 GCN5-related N-acetyl-transferase 12 84 2.2E-24 T 14-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase MCR_1669 2945b1e12f074eee2a8c0388bde4779b 86 Gene3D G3DSA:3.40.630.30 1 86 2.0E-24 T 14-10-2018 MCR_1775 dd2de67c072268169b916d875cdede23 520 Pfam PF02875 Mur ligase family, glutamate ligase domain 363 446 2.1E-18 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MCR_1775 dd2de67c072268169b916d875cdede23 520 SUPERFAMILY SSF53244 363 518 1.83E-45 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_1775 dd2de67c072268169b916d875cdede23 520 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 42 515 2.2E-125 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MCR_1775 dd2de67c072268169b916d875cdede23 520 Gene3D G3DSA:3.40.1190.10 133 366 1.2E-62 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_1775 dd2de67c072268169b916d875cdede23 520 Gene3D G3DSA:3.90.190.20 367 520 1.1E-55 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_1775 dd2de67c072268169b916d875cdede23 520 SUPERFAMILY SSF53623 134 347 5.23E-62 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_1775 dd2de67c072268169b916d875cdede23 520 Pfam PF08245 Mur ligase middle domain 138 340 4.5E-43 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MCR_1775 dd2de67c072268169b916d875cdede23 520 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 27 515 28.952 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MCR_0236 3055cbf19800d3ce59790d89f2b3e467 375 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 39 368 31.22 T 14-10-2018 IPR003770 Endolytic murein transglycosylase MCR_0236 3055cbf19800d3ce59790d89f2b3e467 375 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 32 367 1.1E-86 T 14-10-2018 IPR003770 Endolytic murein transglycosylase MCR_0236 3055cbf19800d3ce59790d89f2b3e467 375 Gene3D G3DSA:3.30.160.60 339 375 1.2E-14 T 14-10-2018 MCR_0236 3055cbf19800d3ce59790d89f2b3e467 375 Pfam PF02618 YceG-like family 65 364 3.7E-79 T 14-10-2018 IPR003770 Endolytic murein transglycosylase MCR_1689 54d4e7153376c027f2e4359eeef1e35f 257 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1689 54d4e7153376c027f2e4359eeef1e35f 257 PIRSF PIRSF039085 6 257 2.2E-115 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MCR_1689 54d4e7153376c027f2e4359eeef1e35f 257 Gene3D G3DSA:3.40.50.300 6 256 9.9E-80 T 14-10-2018 MCR_1689 54d4e7153376c027f2e4359eeef1e35f 257 SUPERFAMILY SSF52540 9 252 2.23E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1689 54d4e7153376c027f2e4359eeef1e35f 257 Pfam PF00005 ABC transporter 24 182 9.4E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1689 54d4e7153376c027f2e4359eeef1e35f 257 SMART SM00382 33 230 7.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1159 4bfb74edf6931a3bd44f7c942abe484d 223 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 8 222 9.4E-82 T 14-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_1159 4bfb74edf6931a3bd44f7c942abe484d 223 Hamap MF_00766 Biosynthetic peptidoglycan transglycosylase [mtgA]. 8 223 37.9 T 14-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_1159 4bfb74edf6931a3bd44f7c942abe484d 223 Pfam PF00912 Transglycosylase 52 217 2.9E-55 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_1159 4bfb74edf6931a3bd44f7c942abe484d 223 SUPERFAMILY SSF53955 50 219 1.43E-58 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MCR_1159 4bfb74edf6931a3bd44f7c942abe484d 223 Gene3D G3DSA:1.10.3810.10 46 222 1.1E-56 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Gene3D G3DSA:1.10.274.100 492 643 2.9E-37 T 14-10-2018 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 SMART SM00663 237 516 1.3E-176 T 14-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Gene3D G3DSA:2.40.50.100 1025 1119 2.4E-22 T 14-10-2018 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Gene3D G3DSA:1.10.40.90 376 418 3.9E-19 T 14-10-2018 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Gene3D G3DSA:2.40.50.100 1144 1207 1.7E-62 T 14-10-2018 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Pfam PF04998 RNA polymerase Rpb1, domain 5 769 1307 1.7E-77 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 SUPERFAMILY SSF64484 17 1356 0.0 T 14-10-2018 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 22 1359 0.0 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Pfam PF04983 RNA polymerase Rpb1, domain 3 491 647 1.6E-24 T 14-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Pfam PF05000 RNA polymerase Rpb1, domain 4 677 766 1.1E-19 T 14-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 12 1368 18.81 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Pfam PF04997 RNA polymerase Rpb1, domain 1 17 344 6.7E-89 T 14-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Pfam PF00623 RNA polymerase Rpb1, domain 2 346 487 1.1E-32 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Gene3D G3DSA:1.10.150.390 1308 1368 8.3E-27 T 14-10-2018 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Gene3D G3DSA:2.40.50.100 950 1024 2.1E-27 T 14-10-2018 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Gene3D G3DSA:1.10.132.30 644 793 1.6E-66 T 14-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0258 ce416b3ba4486c7acd8fc8265d13ad89 1412 Gene3D G3DSA:1.10.1790.20 1128 1306 1.7E-62 T 14-10-2018 MCR_0831 cca407c75a6bcd1bcdca3f526220f213 143 Gene3D G3DSA:3.30.70.141 1 143 2.0E-58 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MCR_0831 cca407c75a6bcd1bcdca3f526220f213 143 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 14-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0831 cca407c75a6bcd1bcdca3f526220f213 143 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.838 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MCR_0831 cca407c75a6bcd1bcdca3f526220f213 143 Pfam PF00334 Nucleoside diphosphate kinase 4 138 5.9E-54 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MCR_0831 cca407c75a6bcd1bcdca3f526220f213 143 SUPERFAMILY SSF54919 1 140 1.05E-56 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MCR_0831 cca407c75a6bcd1bcdca3f526220f213 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.2E-39 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MCR_0831 cca407c75a6bcd1bcdca3f526220f213 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.2E-39 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MCR_0831 cca407c75a6bcd1bcdca3f526220f213 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.2E-39 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MCR_0831 cca407c75a6bcd1bcdca3f526220f213 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 1.2E-39 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MCR_0831 cca407c75a6bcd1bcdca3f526220f213 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.2E-39 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MCR_0831 cca407c75a6bcd1bcdca3f526220f213 143 SMART SM00562 3 140 3.4E-84 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MCR_0808 ad6203ba991c012fac8fa8e46da01497 147 Gene3D G3DSA:3.10.180.10 3 145 5.0E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MCR_0808 ad6203ba991c012fac8fa8e46da01497 147 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 135 1.6E-16 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MCR_0808 ad6203ba991c012fac8fa8e46da01497 147 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 115 134 - T 14-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 MCR_0808 ad6203ba991c012fac8fa8e46da01497 147 SUPERFAMILY SSF54593 4 138 1.28E-34 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MCR_1184 3fdf3cc8da5edf8deb1fc8c994e5f3ff 325 SUPERFAMILY SSF52096 69 267 4.13E-30 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MCR_1184 3fdf3cc8da5edf8deb1fc8c994e5f3ff 325 Pfam PF01343 Peptidase family S49 131 269 2.8E-42 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MCR_1184 3fdf3cc8da5edf8deb1fc8c994e5f3ff 325 Pfam PF08496 Peptidase family S49 N-terminal 6 127 7.2E-34 T 14-10-2018 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 MCR_1184 3fdf3cc8da5edf8deb1fc8c994e5f3ff 325 Gene3D G3DSA:3.90.226.10 74 268 4.1E-44 T 14-10-2018 MCR_1184 3fdf3cc8da5edf8deb1fc8c994e5f3ff 325 Gene3D G3DSA:3.40.1750.20 171 235 4.1E-44 T 14-10-2018 MCR_0039 c39563eb45dccdd67b3c4d7e96c8e7ae 294 SUPERFAMILY SSF161098 98 282 3.53E-24 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0039 c39563eb45dccdd67b3c4d7e96c8e7ae 294 Gene3D G3DSA:1.10.3720.10 101 292 1.7E-19 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0039 c39563eb45dccdd67b3c4d7e96c8e7ae 294 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 86 285 2.0E-63 T 14-10-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 MCR_0039 c39563eb45dccdd67b3c4d7e96c8e7ae 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 291 1.5E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_0157 4447a7568c761964d1481c67ef7758b7 64 Pfam PF11127 Protein of unknown function (DUF2892) 1 62 4.4E-23 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 MCR_0974 2eb42674a61285be55de2aaad2e1cf8e 387 Gene3D G3DSA:1.10.287.470 136 154 1.2E-7 T 14-10-2018 MCR_0974 2eb42674a61285be55de2aaad2e1cf8e 387 Pfam PF13533 Biotin-lipoyl like 102 150 5.2E-10 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MCR_0974 2eb42674a61285be55de2aaad2e1cf8e 387 Gene3D G3DSA:1.10.287.470 242 260 1.7E-8 T 14-10-2018 MCR_0974 2eb42674a61285be55de2aaad2e1cf8e 387 SUPERFAMILY SSF111369 172 313 1.96E-6 T 14-10-2018 MCR_0974 2eb42674a61285be55de2aaad2e1cf8e 387 Gene3D G3DSA:2.40.50.100 262 299 1.7E-8 T 14-10-2018 MCR_0974 2eb42674a61285be55de2aaad2e1cf8e 387 Gene3D G3DSA:2.40.50.100 102 135 1.2E-7 T 14-10-2018 MCR_0974 2eb42674a61285be55de2aaad2e1cf8e 387 Gene3D G3DSA:2.40.30.170 300 315 1.7E-8 T 14-10-2018 MCR_0974 2eb42674a61285be55de2aaad2e1cf8e 387 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 114 134 1.3E-5 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MCR_0974 2eb42674a61285be55de2aaad2e1cf8e 387 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 368 387 1.3E-5 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MCR_0974 2eb42674a61285be55de2aaad2e1cf8e 387 Gene3D G3DSA:1.10.287.470 170 232 4.9E-6 T 14-10-2018 MCR_1732 004eb108198834377cca1ba7483ddfdb 290 Gene3D G3DSA:1.10.3720.10 69 289 2.5E-28 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1732 004eb108198834377cca1ba7483ddfdb 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 285 7.5E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_1732 004eb108198834377cca1ba7483ddfdb 290 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 25 288 5.6E-78 T 14-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 MCR_1732 004eb108198834377cca1ba7483ddfdb 290 SUPERFAMILY SSF161098 34 282 5.23E-32 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0759 d2925a22fbafcf9784c36a12d7f5b0bd 179 Gene3D G3DSA:3.90.550.10 1 177 6.1E-21 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_0759 d2925a22fbafcf9784c36a12d7f5b0bd 179 Pfam PF12804 MobA-like NTP transferase domain 1 144 1.3E-11 T 14-10-2018 IPR025877 MobA-like NTP transferase MCR_0759 d2925a22fbafcf9784c36a12d7f5b0bd 179 SUPERFAMILY SSF53448 4 173 1.03E-9 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_0282 40970c4a459c1f2cf283583f1555f155 174 Gene3D G3DSA:3.40.630.30 1 172 1.8E-39 T 14-10-2018 MCR_0282 40970c4a459c1f2cf283583f1555f155 174 Pfam PF13302 Acetyltransferase (GNAT) domain 29 149 5.9E-20 T 14-10-2018 IPR000182 GNAT domain MCR_0282 40970c4a459c1f2cf283583f1555f155 174 SUPERFAMILY SSF55729 7 170 9.37E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MCR_1851 4461f81122d5c2b76b12c2367a331afa 185 Gene3D G3DSA:3.40.1740.10 2 185 1.5E-52 T 14-10-2018 MCR_1851 4461f81122d5c2b76b12c2367a331afa 185 Pfam PF02622 Uncharacterized ACR, COG1678 16 172 1.9E-35 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 MCR_1851 4461f81122d5c2b76b12c2367a331afa 185 SUPERFAMILY SSF143456 7 183 2.09E-48 T 14-10-2018 MCR_1851 4461f81122d5c2b76b12c2367a331afa 185 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 5 185 27.771 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 MCR_1039 08ffeb3486f45bf7b6bd51ccb4ba6245 164 PRINTS PR00601 Bacterioferritin signature 44 64 1.3E-38 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1039 08ffeb3486f45bf7b6bd51ccb4ba6245 164 PRINTS PR00601 Bacterioferritin signature 3 22 1.3E-38 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1039 08ffeb3486f45bf7b6bd51ccb4ba6245 164 PRINTS PR00601 Bacterioferritin signature 23 43 1.3E-38 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1039 08ffeb3486f45bf7b6bd51ccb4ba6245 164 PRINTS PR00601 Bacterioferritin signature 85 105 1.3E-38 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1039 08ffeb3486f45bf7b6bd51ccb4ba6245 164 PRINTS PR00601 Bacterioferritin signature 128 149 1.3E-38 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1039 08ffeb3486f45bf7b6bd51ccb4ba6245 164 PRINTS PR00601 Bacterioferritin signature 106 126 1.3E-38 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1039 08ffeb3486f45bf7b6bd51ccb4ba6245 164 SUPERFAMILY SSF47240 1 153 1.4E-45 T 14-10-2018 IPR009078 Ferritin-like superfamily MCR_1039 08ffeb3486f45bf7b6bd51ccb4ba6245 164 Gene3D G3DSA:1.20.1260.10 1 153 3.9E-60 T 14-10-2018 IPR012347 Ferritin-like MCR_1039 08ffeb3486f45bf7b6bd51ccb4ba6245 164 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 3.1E-47 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_1039 08ffeb3486f45bf7b6bd51ccb4ba6245 164 Pfam PF00210 Ferritin-like domain 8 144 1.3E-32 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MCR_1039 08ffeb3486f45bf7b6bd51ccb4ba6245 164 PIRSF PIRSF002560 1 157 1.0E-59 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MCR_0743 cee1ff19159877234c43cb57375c491e 107 Pfam PF05940 NnrS protein 15 106 1.4E-29 T 14-10-2018 IPR010266 NnrS MCR_0421 27970f0fd3a7b5c86bb181c1808bdfb8 162 Gene3D G3DSA:3.30.1050.10 25 130 6.2E-6 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily MCR_1638 1fbd37609cb037f82693bbabc3b0ab98 78 SUPERFAMILY SSF89447 10 72 1.2E-6 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily MCR_1638 1fbd37609cb037f82693bbabc3b0ab98 78 Gene3D G3DSA:2.10.260.10 5 78 5.0E-8 T 14-10-2018 MCR_1275 3fe2bc6b3299c2af3f6dd8faf2eaf9c0 75 Gene3D G3DSA:4.10.640.10 1 75 6.4E-28 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1275 3fe2bc6b3299c2af3f6dd8faf2eaf9c0 75 Pfam PF01084 Ribosomal protein S18 18 68 1.2E-25 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1275 3fe2bc6b3299c2af3f6dd8faf2eaf9c0 75 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 14-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1275 3fe2bc6b3299c2af3f6dd8faf2eaf9c0 75 SUPERFAMILY SSF46911 3 74 5.89E-31 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1275 3fe2bc6b3299c2af3f6dd8faf2eaf9c0 75 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 21.654 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1275 3fe2bc6b3299c2af3f6dd8faf2eaf9c0 75 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 3.6E-19 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1275 3fe2bc6b3299c2af3f6dd8faf2eaf9c0 75 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 3.6E-19 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1275 3fe2bc6b3299c2af3f6dd8faf2eaf9c0 75 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 3.6E-19 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1275 3fe2bc6b3299c2af3f6dd8faf2eaf9c0 75 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 3.6E-19 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1275 3fe2bc6b3299c2af3f6dd8faf2eaf9c0 75 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 20 71 8.0E-22 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1275 3fe2bc6b3299c2af3f6dd8faf2eaf9c0 75 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 72 6.4E-37 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1271 df79dfd1f9ede23741a5e1d80b89854b 280 SUPERFAMILY SSF81324 32 245 1.31E-49 T 14-10-2018 MCR_1271 df79dfd1f9ede23741a5e1d80b89854b 280 Pfam PF00520 Ion transport protein 33 243 1.2E-25 T 14-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 MCR_1271 df79dfd1f9ede23741a5e1d80b89854b 280 PRINTS PR00169 Potassium channel signature 130 156 7.5E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MCR_1271 df79dfd1f9ede23741a5e1d80b89854b 280 PRINTS PR00169 Potassium channel signature 68 91 7.5E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MCR_1271 df79dfd1f9ede23741a5e1d80b89854b 280 PRINTS PR00169 Potassium channel signature 159 182 7.5E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MCR_1271 df79dfd1f9ede23741a5e1d80b89854b 280 PRINTS PR00169 Potassium channel signature 94 114 7.5E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MCR_1271 df79dfd1f9ede23741a5e1d80b89854b 280 PRINTS PR00169 Potassium channel signature 217 243 7.5E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MCR_1271 df79dfd1f9ede23741a5e1d80b89854b 280 PRINTS PR00169 Potassium channel signature 26 54 7.5E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MCR_1271 df79dfd1f9ede23741a5e1d80b89854b 280 PRINTS PR00169 Potassium channel signature 188 210 7.5E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MCR_1271 df79dfd1f9ede23741a5e1d80b89854b 280 Gene3D G3DSA:1.10.287.70 32 247 4.7E-54 T 14-10-2018 MCR_1223 fc47ee308eb12594b45b37120c55507f 315 SUPERFAMILY SSF55811 2 112 4.33E-19 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MCR_1223 fc47ee308eb12594b45b37120c55507f 315 Gene3D G3DSA:3.20.20.70 169 315 1.4E-17 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1223 fc47ee308eb12594b45b37120c55507f 315 Pfam PF02581 Thiamine monophosphate synthase 221 305 2.7E-11 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MCR_1223 fc47ee308eb12594b45b37120c55507f 315 Gene3D G3DSA:3.90.79.10 1 113 1.0E-19 T 14-10-2018 MCR_1223 fc47ee308eb12594b45b37120c55507f 315 Pfam PF00293 NUDIX domain 4 112 4.0E-13 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MCR_1223 fc47ee308eb12594b45b37120c55507f 315 SUPERFAMILY SSF51391 214 310 9.55E-14 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MCR_1223 fc47ee308eb12594b45b37120c55507f 315 ProSitePatterns PS00893 Nudix box signature. 14 35 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MCR_1831 6837d133ef588be71519bd24b5d6215b 209 Gene3D G3DSA:3.90.220.20 12 156 3.1E-37 T 14-10-2018 MCR_1831 6837d133ef588be71519bd24b5d6215b 209 SUPERFAMILY SSF116734 14 206 4.58E-44 T 14-10-2018 MCR_1831 6837d133ef588be71519bd24b5d6215b 209 Pfam PF01420 Type I restriction modification DNA specificity domain 15 189 2.1E-30 T 14-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 Gene3D G3DSA:1.10.1390.10 497 542 4.0E-15 T 14-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 35 514 38.025 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 Pfam PF00342 Phosphoglucose isomerase 41 531 9.8E-178 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 Gene3D G3DSA:3.40.50.10490 9 496 2.5E-203 T 14-10-2018 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 487 504 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 SUPERFAMILY SSF53697 3 536 2.67E-180 T 14-10-2018 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 PRINTS PR00662 Glucose-6-phosphate isomerase signature 473 487 5.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 PRINTS PR00662 Glucose-6-phosphate isomerase signature 329 350 5.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 PRINTS PR00662 Glucose-6-phosphate isomerase signature 455 473 5.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 PRINTS PR00662 Glucose-6-phosphate isomerase signature 252 270 5.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 PRINTS PR00662 Glucose-6-phosphate isomerase signature 487 500 5.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 PRINTS PR00662 Glucose-6-phosphate isomerase signature 139 158 5.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 256 269 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1808 5431a1c01fe601e7f16b5fee9bb53522 542 Gene3D G3DSA:3.40.50.10490 87 282 2.5E-203 T 14-10-2018 MCR_1063 7b91ca156b4d0f5247e5f47d5b429d8e 418 SUPERFAMILY SSF52096 71 396 1.29E-57 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MCR_1063 7b91ca156b4d0f5247e5f47d5b429d8e 418 Gene3D G3DSA:2.30.42.10 130 219 2.3E-75 T 14-10-2018 MCR_1063 7b91ca156b4d0f5247e5f47d5b429d8e 418 Pfam PF03572 Peptidase family S41 230 389 4.5E-44 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MCR_1063 7b91ca156b4d0f5247e5f47d5b429d8e 418 Pfam PF13180 PDZ domain 141 207 1.7E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MCR_1063 7b91ca156b4d0f5247e5f47d5b429d8e 418 SMART SM00228 128 204 0.0018 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MCR_1063 7b91ca156b4d0f5247e5f47d5b429d8e 418 SUPERFAMILY SSF50156 124 208 1.26E-10 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 MCR_1063 7b91ca156b4d0f5247e5f47d5b429d8e 418 Gene3D G3DSA:3.30.750.44 76 366 2.3E-75 T 14-10-2018 MCR_1063 7b91ca156b4d0f5247e5f47d5b429d8e 418 Gene3D G3DSA:3.90.226.10 220 388 2.3E-75 T 14-10-2018 MCR_1063 7b91ca156b4d0f5247e5f47d5b429d8e 418 SMART SM00245 205 391 5.3E-44 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MCR_1063 7b91ca156b4d0f5247e5f47d5b429d8e 418 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 82 398 6.6E-70 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 MCR_1183 12fd2db85ba9d12ca257804a860f4071 300 Gene3D G3DSA:3.40.50.720 49 292 2.2E-49 T 14-10-2018 MCR_1183 12fd2db85ba9d12ca257804a860f4071 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 141 3.9E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1183 12fd2db85ba9d12ca257804a860f4071 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 244 3.9E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1183 12fd2db85ba9d12ca257804a860f4071 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 193 3.9E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1183 12fd2db85ba9d12ca257804a860f4071 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 55 72 3.9E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1183 12fd2db85ba9d12ca257804a860f4071 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 223 3.9E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1183 12fd2db85ba9d12ca257804a860f4071 300 SUPERFAMILY SSF51735 52 281 2.31E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1183 12fd2db85ba9d12ca257804a860f4071 300 Pfam PF00106 short chain dehydrogenase 54 244 1.6E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1183 12fd2db85ba9d12ca257804a860f4071 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 183 191 6.9E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1183 12fd2db85ba9d12ca257804a860f4071 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 204 223 6.9E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1183 12fd2db85ba9d12ca257804a860f4071 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 141 6.9E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0605 b46cab05b810536c524262ecbad9322d 172 Gene3D G3DSA:1.10.287.110 4 76 4.7E-17 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MCR_0605 b46cab05b810536c524262ecbad9322d 172 Gene3D G3DSA:1.20.1280.20 77 163 4.1E-15 T 14-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MCR_0605 b46cab05b810536c524262ecbad9322d 172 Pfam PF07743 HSCB C-terminal oligomerisation domain 84 155 5.6E-11 T 14-10-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MCR_0605 b46cab05b810536c524262ecbad9322d 172 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 16 159 2.3E-22 T 14-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MCR_0605 b46cab05b810536c524262ecbad9322d 172 SMART SM00271 4 63 1.5E-6 T 14-10-2018 IPR001623 DnaJ domain MCR_0605 b46cab05b810536c524262ecbad9322d 172 SUPERFAMILY SSF47144 77 161 5.1E-12 T 14-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MCR_0605 b46cab05b810536c524262ecbad9322d 172 Pfam PF00226 DnaJ domain 15 67 1.6E-8 T 14-10-2018 IPR001623 DnaJ domain MCR_0605 b46cab05b810536c524262ecbad9322d 172 SUPERFAMILY SSF46565 5 71 2.88E-13 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MCR_1475 c995dc597ecf62c4b6a729cc3b76d098 201 Pfam PF01694 Rhomboid family 36 182 8.9E-28 T 14-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MCR_1475 c995dc597ecf62c4b6a729cc3b76d098 201 Gene3D G3DSA:1.20.1540.10 1 190 6.9E-28 T 14-10-2018 IPR035952 Rhomboid-like superfamily MCR_1475 c995dc597ecf62c4b6a729cc3b76d098 201 SUPERFAMILY SSF144091 3 186 5.62E-37 T 14-10-2018 MCR_0867 5c4c9b40667896e4383ee3a7b72c5149 237 Gene3D G3DSA:3.40.50.300 5 236 1.4E-71 T 14-10-2018 MCR_0867 5c4c9b40667896e4383ee3a7b72c5149 237 TIGRFAM TIGR00017 cmk: cytidylate kinase 12 229 2.2E-65 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MCR_0867 5c4c9b40667896e4383ee3a7b72c5149 237 SUPERFAMILY SSF52540 10 234 3.64E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0867 5c4c9b40667896e4383ee3a7b72c5149 237 Pfam PF02224 Cytidylate kinase 14 232 8.6E-64 T 14-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MCR_0867 5c4c9b40667896e4383ee3a7b72c5149 237 Hamap MF_00238 Cytidylate kinase [cmk]. 12 235 31.348 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MCR_1435 204c89222aa4d0d946e6ea988532072a 208 SUPERFAMILY SSF53056 6 207 1.31E-49 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MCR_1435 204c89222aa4d0d946e6ea988532072a 208 Pfam PF00484 Carbonic anhydrase 45 203 7.2E-37 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MCR_1435 204c89222aa4d0d946e6ea988532072a 208 SMART SM00947 38 207 7.3E-48 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MCR_1435 204c89222aa4d0d946e6ea988532072a 208 Gene3D G3DSA:3.40.1050.10 1 208 1.9E-54 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MCR_0019 6e0ca03320268dce00af847a7abd3d71 252 Pfam PF02602 Uroporphyrinogen-III synthase HemD 22 221 3.4E-26 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0019 6e0ca03320268dce00af847a7abd3d71 252 Gene3D G3DSA:3.40.50.10090 32 171 2.5E-35 T 14-10-2018 MCR_0019 6e0ca03320268dce00af847a7abd3d71 252 SUPERFAMILY SSF69618 6 231 1.83E-32 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MCR_0019 6e0ca03320268dce00af847a7abd3d71 252 Gene3D G3DSA:3.40.50.10090 8 226 2.5E-35 T 14-10-2018 MCR_1176 b2518c6b3385f878fd3103b604264119 413 SUPERFAMILY SSF51197 42 335 1.26E-56 T 14-10-2018 MCR_1176 b2518c6b3385f878fd3103b604264119 413 SMART SM00558 115 263 2.0E-6 T 14-10-2018 IPR003347 JmjC domain MCR_1176 b2518c6b3385f878fd3103b604264119 413 Gene3D G3DSA:2.60.120.650 27 248 3.1E-68 T 14-10-2018 MCR_1176 b2518c6b3385f878fd3103b604264119 413 Gene3D G3DSA:1.10.10.2510 251 412 4.0E-14 T 14-10-2018 MCR_1176 b2518c6b3385f878fd3103b604264119 413 Pfam PF08007 Cupin superfamily protein 48 351 1.8E-79 T 14-10-2018 IPR003347 JmjC domain MCR_0396 75051cc075962d5300e5bd0dca269835 517 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 508 44.577 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_0396 75051cc075962d5300e5bd0dca269835 517 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 14-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 MCR_0396 75051cc075962d5300e5bd0dca269835 517 SUPERFAMILY SSF48557 4 505 7.85E-186 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 MCR_0396 75051cc075962d5300e5bd0dca269835 517 Gene3D G3DSA:1.10.275.10 2 197 2.2E-68 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal MCR_0396 75051cc075962d5300e5bd0dca269835 517 Pfam PF00221 Aromatic amino acid lyase 11 475 1.5E-183 T 14-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 MCR_0396 75051cc075962d5300e5bd0dca269835 517 Gene3D G3DSA:1.20.200.10 198 509 9.6E-114 T 14-10-2018 MCR_0396 75051cc075962d5300e5bd0dca269835 517 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 5 505 3.5E-208 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MCR_1594 55b58311c665b950b76ad92ae23bd188 174 Gene3D G3DSA:1.10.760.10 87 174 5.3E-23 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1594 55b58311c665b950b76ad92ae23bd188 174 SUPERFAMILY SSF46626 94 171 9.01E-12 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1594 55b58311c665b950b76ad92ae23bd188 174 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 94 169 5.5E-11 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1179 fdaebf441d718e55d62074bf406b8cf4 294 Pfam PF00588 SpoU rRNA Methylase family 13 185 2.0E-24 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MCR_1179 fdaebf441d718e55d62074bf406b8cf4 294 PIRSF PIRSF004808 8 121 7.1E-25 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 MCR_1179 fdaebf441d718e55d62074bf406b8cf4 294 PIRSF PIRSF004808 211 294 0.063 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 MCR_1179 fdaebf441d718e55d62074bf406b8cf4 294 PIRSF PIRSF004808 112 217 2.4E-19 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 MCR_1179 fdaebf441d718e55d62074bf406b8cf4 294 SUPERFAMILY SSF75217 11 193 4.11E-26 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MCR_1179 fdaebf441d718e55d62074bf406b8cf4 294 Gene3D G3DSA:3.40.1280.10 9 196 4.1E-47 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MCR_0866 3a4dac93dcfa9825c53f603ebe2cb96b 159 Pfam PF14437 MafB19-like deaminase 4 149 2.2E-29 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MCR_0866 3a4dac93dcfa9825c53f603ebe2cb96b 159 Gene3D G3DSA:3.40.140.10 1 159 6.7E-55 T 14-10-2018 MCR_0866 3a4dac93dcfa9825c53f603ebe2cb96b 159 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 90 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MCR_0866 3a4dac93dcfa9825c53f603ebe2cb96b 159 SUPERFAMILY SSF53927 2 152 1.0E-51 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MCR_0866 3a4dac93dcfa9825c53f603ebe2cb96b 159 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 149 43.41 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MCR_0603 e78ca477a3d54726f269df4780227b25 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 4 111 7.2E-54 T 14-10-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 MCR_0603 e78ca477a3d54726f269df4780227b25 112 PRINTS PR00355 Adrenodoxin signature 42 52 4.9E-8 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MCR_0603 e78ca477a3d54726f269df4780227b25 112 PRINTS PR00355 Adrenodoxin signature 83 91 4.9E-8 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MCR_0603 e78ca477a3d54726f269df4780227b25 112 PRINTS PR00355 Adrenodoxin signature 60 74 4.9E-8 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MCR_0603 e78ca477a3d54726f269df4780227b25 112 Gene3D G3DSA:3.10.20.30 1 112 6.3E-33 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MCR_0603 e78ca477a3d54726f269df4780227b25 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 91 2.8E-12 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MCR_0603 e78ca477a3d54726f269df4780227b25 112 SUPERFAMILY SSF54292 6 108 6.24E-29 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MCR_0603 e78ca477a3d54726f269df4780227b25 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 14-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MCR_0453 cebdf4fa9aebbb2b143d34c35d270bcd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0453 cebdf4fa9aebbb2b143d34c35d270bcd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0453 cebdf4fa9aebbb2b143d34c35d270bcd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0453 cebdf4fa9aebbb2b143d34c35d270bcd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0453 cebdf4fa9aebbb2b143d34c35d270bcd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0453 cebdf4fa9aebbb2b143d34c35d270bcd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_0453 cebdf4fa9aebbb2b143d34c35d270bcd 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 247 1.1E-40 T 14-10-2018 MCR_0453 cebdf4fa9aebbb2b143d34c35d270bcd 255 Gene3D G3DSA:3.40.50.720 2 252 2.9E-59 T 14-10-2018 MCR_0453 cebdf4fa9aebbb2b143d34c35d270bcd 255 SUPERFAMILY SSF51735 3 250 4.24E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1173 906f48e4babb842a7260186aaaefc358 186 Gene3D G3DSA:1.25.40.10 6 185 4.4E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_1173 906f48e4babb842a7260186aaaefc358 186 Pfam PF13181 Tetratricopeptide repeat 23 54 0.048 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MCR_1173 906f48e4babb842a7260186aaaefc358 186 Pfam PF13432 Tetratricopeptide repeat 77 117 0.0057 T 14-10-2018 MCR_1173 906f48e4babb842a7260186aaaefc358 186 SMART SM00028 56 92 48.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MCR_1173 906f48e4babb842a7260186aaaefc358 186 SMART SM00028 22 55 0.62 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MCR_1173 906f48e4babb842a7260186aaaefc358 186 SUPERFAMILY SSF48452 18 166 2.2E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0733 80b23dca262c052691f02a649f637aa4 249 Gene3D G3DSA:3.30.70.980 84 236 1.3E-51 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_0733 80b23dca262c052691f02a649f637aa4 249 SUPERFAMILY SSF75625 3 246 1.83E-92 T 14-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_0733 80b23dca262c052691f02a649f637aa4 249 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 35.074 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_0733 80b23dca262c052691f02a649f637aa4 249 Gene3D G3DSA:3.30.70.980 133 204 1.3E-51 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_0733 80b23dca262c052691f02a649f637aa4 249 Gene3D G3DSA:1.10.10.200 1 81 5.7E-34 T 14-10-2018 IPR017856 Integrase-like, N-terminal MCR_0733 80b23dca262c052691f02a649f637aa4 249 Pfam PF01709 Transcriptional regulator 5 237 5.8E-96 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_0733 80b23dca262c052691f02a649f637aa4 249 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 6.0E-97 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1897 a91e75a98041d27ebd508fe490a099de 341 Pfam PF00551 Formyl transferase 9 199 1.3E-41 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MCR_1897 a91e75a98041d27ebd508fe490a099de 341 SUPERFAMILY SSF53328 8 225 1.57E-59 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MCR_1897 a91e75a98041d27ebd508fe490a099de 341 Gene3D G3DSA:3.10.25.10 228 331 4.6E-15 T 14-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MCR_1897 a91e75a98041d27ebd508fe490a099de 341 SUPERFAMILY SSF50486 226 328 8.16E-19 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 MCR_1897 a91e75a98041d27ebd508fe490a099de 341 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 9 329 32.575 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MCR_1897 a91e75a98041d27ebd508fe490a099de 341 Pfam PF02911 Formyl transferase, C-terminal domain 225 325 6.8E-21 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MCR_1897 a91e75a98041d27ebd508fe490a099de 341 Gene3D G3DSA:3.40.50.170 3 227 5.3E-74 T 14-10-2018 MCR_1897 a91e75a98041d27ebd508fe490a099de 341 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 9 327 3.8E-79 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MCR_1320 be382b910caeb5ff6701651bb9441841 355 Gene3D G3DSA:1.10.760.10 235 326 6.8E-70 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1320 be382b910caeb5ff6701651bb9441841 355 Gene3D G3DSA:1.10.760.10 166 349 6.8E-70 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1320 be382b910caeb5ff6701651bb9441841 355 PIRSF PIRSF000006 1 353 1.2E-88 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III MCR_1320 be382b910caeb5ff6701651bb9441841 355 Gene3D G3DSA:1.20.58.1490 1 94 2.5E-27 T 14-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily MCR_1320 be382b910caeb5ff6701651bb9441841 355 SUPERFAMILY SSF46626 55 261 5.84E-28 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1320 be382b910caeb5ff6701651bb9441841 355 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 181 254 3.1E-11 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1320 be382b910caeb5ff6701651bb9441841 355 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 270 346 2.6E-13 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1320 be382b910caeb5ff6701651bb9441841 355 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 36 80 6.7E-22 T 14-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal MCR_1320 be382b910caeb5ff6701651bb9441841 355 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 156 351 5.8E-57 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III MCR_1320 be382b910caeb5ff6701651bb9441841 355 SUPERFAMILY SSF46626 261 351 5.01E-25 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_0248 f80221981409bffef2c968f545d7c9e6 296 Pfam PF08220 DeoR-like helix-turn-helix domain 11 56 1.6E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MCR_0248 f80221981409bffef2c968f545d7c9e6 296 Pfam PF13280 WYL domain 124 289 1.7E-27 T 14-10-2018 IPR026881 WYL domain MCR_0248 f80221981409bffef2c968f545d7c9e6 296 ProSitePatterns PS00894 DeoR-type HTH domain signature. 11 45 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MCR_1017 71dbd1f03d640a7422691ed90f11dd34 748 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 5 358 2.4E-132 T 14-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 MCR_1017 71dbd1f03d640a7422691ed90f11dd34 748 Gene3D G3DSA:1.20.272.10 244 364 1.5E-25 T 14-10-2018 MCR_1017 71dbd1f03d640a7422691ed90f11dd34 748 SUPERFAMILY SSF52540 36 224 1.63E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1017 71dbd1f03d640a7422691ed90f11dd34 748 Gene3D G3DSA:1.10.8.60 10 241 2.9E-101 T 14-10-2018 MCR_1017 71dbd1f03d640a7422691ed90f11dd34 748 SUPERFAMILY SSF48019 245 364 6.97E-23 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MCR_1017 71dbd1f03d640a7422691ed90f11dd34 748 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 235 365 8.3E-29 T 14-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 MCR_1017 71dbd1f03d640a7422691ed90f11dd34 748 Pfam PF13177 DNA polymerase III, delta subunit 22 180 4.6E-42 T 14-10-2018 MCR_1017 71dbd1f03d640a7422691ed90f11dd34 748 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 126 144 2.3E-5 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MCR_1017 71dbd1f03d640a7422691ed90f11dd34 748 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 43 61 2.3E-5 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MCR_1017 71dbd1f03d640a7422691ed90f11dd34 748 SMART SM00382 39 180 8.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1017 71dbd1f03d640a7422691ed90f11dd34 748 Gene3D G3DSA:3.40.50.300 15 179 2.9E-101 T 14-10-2018 MCR_0820 4dca659c2eec8d9b9495b12134f9f1ed 193 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 161 2.0E-27 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MCR_0820 4dca659c2eec8d9b9495b12134f9f1ed 193 Gene3D G3DSA:3.40.50.1240 1 174 2.0E-28 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MCR_0820 4dca659c2eec8d9b9495b12134f9f1ed 193 SMART SM00855 3 144 1.6E-5 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MCR_0820 4dca659c2eec8d9b9495b12134f9f1ed 193 SUPERFAMILY SSF53254 1 163 9.57E-31 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MCR_0259 031e4668bdb14c435c7e4c25b952353b 408 Gene3D G3DSA:3.30.70.260 327 407 3.5E-29 T 14-10-2018 MCR_0259 031e4668bdb14c435c7e4c25b952353b 408 SUPERFAMILY SSF52283 7 134 5.86E-49 T 14-10-2018 MCR_0259 031e4668bdb14c435c7e4c25b952353b 408 Gene3D G3DSA:3.40.50.720 108 296 3.7E-108 T 14-10-2018 MCR_0259 031e4668bdb14c435c7e4c25b952353b 408 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 153 180 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MCR_0259 031e4668bdb14c435c7e4c25b952353b 408 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 293 7.5E-53 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MCR_0259 031e4668bdb14c435c7e4c25b952353b 408 SUPERFAMILY SSF55021 330 407 3.56E-19 T 14-10-2018 MCR_0259 031e4668bdb14c435c7e4c25b952353b 408 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 13 325 4.1E-38 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MCR_0259 031e4668bdb14c435c7e4c25b952353b 408 SUPERFAMILY SSF51735 107 294 8.06E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0259 031e4668bdb14c435c7e4c25b952353b 408 Gene3D G3DSA:3.40.50.720 13 311 3.7E-108 T 14-10-2018 MCR_1797 cdfa413df74bddba1fd97f8cfdf08f5d 310 Pfam PF01430 Hsp33 protein 12 293 4.1E-69 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MCR_1797 cdfa413df74bddba1fd97f8cfdf08f5d 310 SUPERFAMILY SSF118352 244 302 9.29E-13 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MCR_1797 cdfa413df74bddba1fd97f8cfdf08f5d 310 Gene3D G3DSA:3.55.30.10 7 191 1.4E-46 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MCR_1797 cdfa413df74bddba1fd97f8cfdf08f5d 310 SUPERFAMILY SSF64397 11 252 3.4E-59 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MCR_1797 cdfa413df74bddba1fd97f8cfdf08f5d 310 Gene3D G3DSA:1.10.287.480 196 244 1.4E-17 T 14-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily MCR_1797 cdfa413df74bddba1fd97f8cfdf08f5d 310 PIRSF PIRSF005261 2 304 1.2E-66 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MCR_1797 cdfa413df74bddba1fd97f8cfdf08f5d 310 Gene3D G3DSA:3.90.1280.10 245 304 9.3E-15 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MCR_1461 7ff4c83325949f2fb323c15cd6fa13c6 223 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 191 4.1E-60 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MCR_1461 7ff4c83325949f2fb323c15cd6fa13c6 223 PIRSF PIRSF006102 1 210 4.5E-66 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MCR_1461 7ff4c83325949f2fb323c15cd6fa13c6 223 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 4 204 1.3E-92 T 14-10-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 MCR_1461 7ff4c83325949f2fb323c15cd6fa13c6 223 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 1 204 32.709 T 14-10-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 MCR_0819 7213cfea04c834fc19f49f8fbb1ff2a5 253 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 2 247 38.046 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 MCR_0819 7213cfea04c834fc19f49f8fbb1ff2a5 253 SUPERFAMILY SSF53448 4 244 2.09E-57 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_0819 7213cfea04c834fc19f49f8fbb1ff2a5 253 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 5 240 6.5E-77 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 MCR_0819 7213cfea04c834fc19f49f8fbb1ff2a5 253 Gene3D G3DSA:3.90.550.10 1 245 1.2E-85 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_0819 7213cfea04c834fc19f49f8fbb1ff2a5 253 Pfam PF02348 Cytidylyltransferase 7 220 4.6E-56 T 14-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 MCR_1457 9a606312ccd054a86c4b57ea35612674 243 Gene3D G3DSA:3.20.20.70 4 242 4.9E-84 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1457 9a606312ccd054a86c4b57ea35612674 243 SUPERFAMILY SSF51366 3 239 5.25E-71 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MCR_1457 9a606312ccd054a86c4b57ea35612674 243 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 240 34.426 T 14-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MCR_1457 9a606312ccd054a86c4b57ea35612674 243 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 5 235 4.0E-75 T 14-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MCR_1457 9a606312ccd054a86c4b57ea35612674 243 Pfam PF00977 Histidine biosynthesis protein 5 232 7.3E-76 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 MCR_1061 714bc4bea0ae0ff1d66adfee378a507a 88 Pfam PF01649 Ribosomal protein S20 2 84 6.3E-27 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1061 714bc4bea0ae0ff1d66adfee378a507a 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 88 4.0E-28 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1061 714bc4bea0ae0ff1d66adfee378a507a 88 SUPERFAMILY SSF46992 3 86 1.05E-30 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1061 714bc4bea0ae0ff1d66adfee378a507a 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 6.5E-28 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1061 714bc4bea0ae0ff1d66adfee378a507a 88 Gene3D G3DSA:1.20.58.110 1 87 1.7E-28 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1061 714bc4bea0ae0ff1d66adfee378a507a 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.883 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1066 127efdb935f8a35bd542cdf715de3fb8 195 Gene3D G3DSA:1.10.357.10 26 195 4.7E-27 T 14-10-2018 MCR_1066 127efdb935f8a35bd542cdf715de3fb8 195 SUPERFAMILY SSF46689 20 95 1.8E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MCR_1066 127efdb935f8a35bd542cdf715de3fb8 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 78 8.6E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MCR_1066 127efdb935f8a35bd542cdf715de3fb8 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 1.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MCR_1066 127efdb935f8a35bd542cdf715de3fb8 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 1.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MCR_0332 ecb65a82f292a57f5df41aadc0056ad6 122 Gene3D G3DSA:3.30.1450.10 32 122 1.5E-26 T 14-10-2018 IPR037873 BamE-like MCR_0332 ecb65a82f292a57f5df41aadc0056ad6 122 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 2 119 27.092 T 14-10-2018 IPR026592 Outer membrane protein assembly factor BamE MCR_0332 ecb65a82f292a57f5df41aadc0056ad6 122 Pfam PF04355 SmpA / OmlA family 33 111 3.5E-21 T 14-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 MCR_0606 050d48011237d1299436f82fb71960f8 106 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 102 5.7E-24 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MCR_0606 050d48011237d1299436f82fb71960f8 106 Gene3D G3DSA:2.60.300.12 1 106 1.6E-37 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MCR_0606 050d48011237d1299436f82fb71960f8 106 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 87 104 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MCR_0606 050d48011237d1299436f82fb71960f8 106 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 106 3.3E-37 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MCR_0606 050d48011237d1299436f82fb71960f8 106 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 2 106 4.0E-49 T 14-10-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 MCR_0606 050d48011237d1299436f82fb71960f8 106 SUPERFAMILY SSF89360 1 95 7.32E-33 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MCR_0731 cdc36c2cad1dc026e74d927923d9ac2d 47 Pfam PF09521 NgoPII restriction endonuclease 2 45 2.1E-10 T 14-10-2018 IPR019046 Restriction endonuclease, type II, NgoPII GO:0003677|GO:0009036|GO:0009307 MCR_0980 cfa744a4e2a3c54b6158001c669284a7 420 Gene3D G3DSA:3.40.50.10070 29 159 9.9E-9 T 14-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 MCR_0980 cfa744a4e2a3c54b6158001c669284a7 420 SUPERFAMILY SSF69304 161 419 1.96E-33 T 14-10-2018 MCR_0980 cfa744a4e2a3c54b6158001c669284a7 420 SUPERFAMILY SSF52964 39 155 2.75E-8 T 14-10-2018 MCR_0980 cfa744a4e2a3c54b6158001c669284a7 420 Gene3D G3DSA:2.120.10.30 161 420 3.9E-43 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MCR_0980 cfa744a4e2a3c54b6158001c669284a7 420 Pfam PF07676 WD40-like Beta Propeller Repeat 371 393 0.0029 T 14-10-2018 IPR011659 WD40-like Beta Propeller MCR_0980 cfa744a4e2a3c54b6158001c669284a7 420 Pfam PF07676 WD40-like Beta Propeller Repeat 330 349 0.003 T 14-10-2018 IPR011659 WD40-like Beta Propeller MCR_0980 cfa744a4e2a3c54b6158001c669284a7 420 Pfam PF07676 WD40-like Beta Propeller Repeat 235 271 1.8E-6 T 14-10-2018 IPR011659 WD40-like Beta Propeller MCR_0162 6cba7112a994db4aa10a21475cf8c0c9 280 SUPERFAMILY SSF53335 65 272 2.07E-17 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0162 6cba7112a994db4aa10a21475cf8c0c9 280 Pfam PF08241 Methyltransferase domain 70 161 2.2E-6 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MCR_0162 6cba7112a994db4aa10a21475cf8c0c9 280 Gene3D G3DSA:3.40.50.150 60 273 1.3E-14 T 14-10-2018 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 SUPERFAMILY SSF53098 351 540 1.73E-52 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 SMART SM00482 708 912 4.9E-101 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 33 194 6.7E-52 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 SMART SM00475 29 285 1.9E-115 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 TIGRFAM TIGR00593 pola: DNA polymerase I 34 959 2.4E-270 T 14-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 Gene3D G3DSA:1.10.150.20 731 874 4.0E-105 T 14-10-2018 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 SMART SM00279 197 232 3.6E-12 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 ProSitePatterns PS00447 DNA polymerase family A signature. 776 795 - T 14-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 Gene3D G3DSA:3.30.420.10 350 566 2.0E-66 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 SUPERFAMILY SSF56672 548 959 5.0E-144 T 14-10-2018 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 SUPERFAMILY SSF47807 195 311 3.59E-25 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 Gene3D G3DSA:1.10.150.20 198 270 3.2E-90 T 14-10-2018 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 Gene3D G3DSA:3.40.50.1010 34 307 3.2E-90 T 14-10-2018 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 Pfam PF00476 DNA polymerase family A 577 956 5.6E-145 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 Pfam PF01612 3'-5' exonuclease 352 541 1.8E-37 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 Gene3D G3DSA:3.30.70.370 686 955 4.0E-105 T 14-10-2018 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 SUPERFAMILY SSF88723 27 194 9.32E-55 T 14-10-2018 IPR029060 PIN-like domain superfamily MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 PRINTS PR00868 DNA-polymerase family A (pol I) signature 677 699 1.3E-75 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 PRINTS PR00868 DNA-polymerase family A (pol I) signature 835 846 1.3E-75 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 PRINTS PR00868 DNA-polymerase family A (pol I) signature 722 745 1.3E-75 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 PRINTS PR00868 DNA-polymerase family A (pol I) signature 895 908 1.3E-75 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 PRINTS PR00868 DNA-polymerase family A (pol I) signature 752 765 1.3E-75 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 PRINTS PR00868 DNA-polymerase family A (pol I) signature 700 715 1.3E-75 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 PRINTS PR00868 DNA-polymerase family A (pol I) signature 813 824 1.3E-75 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 PRINTS PR00868 DNA-polymerase family A (pol I) signature 776 801 1.3E-75 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 PRINTS PR00868 DNA-polymerase family A (pol I) signature 867 883 1.3E-75 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 195 287 1.1E-25 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 Gene3D G3DSA:1.20.1060.10 568 680 1.3E-35 T 14-10-2018 MCR_1683 01bf9f0e4d446103dfc051e054a3b996 959 SMART SM00474 352 542 6.2E-32 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MCR_0406 be432c0b37beb04da63af46f7bdaa4bc 385 Pfam PF01979 Amidohydrolase family 173 337 9.3E-8 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MCR_0406 be432c0b37beb04da63af46f7bdaa4bc 385 SUPERFAMILY SSF51338 345 385 1.34E-8 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MCR_0406 be432c0b37beb04da63af46f7bdaa4bc 385 Gene3D G3DSA:3.20.20.140 28 340 2.3E-85 T 14-10-2018 MCR_0406 be432c0b37beb04da63af46f7bdaa4bc 385 Gene3D G3DSA:2.30.40.10 16 385 2.3E-85 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MCR_0406 be432c0b37beb04da63af46f7bdaa4bc 385 SUPERFAMILY SSF51556 28 338 4.08E-80 T 14-10-2018 IPR032466 Metal-dependent hydrolase MCR_1606 eb3e0b0ae90be90ced61db590adb3113 183 Pfam PF06271 RDD family 3 158 1.0E-22 T 14-10-2018 IPR010432 RDD MCR_0286 840ab7cd4d25a1bed9197e0d40384526 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.1E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_0286 840ab7cd4d25a1bed9197e0d40384526 300 Gene3D G3DSA:1.10.10.10 1 85 3.5E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0286 840ab7cd4d25a1bed9197e0d40384526 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_0286 840ab7cd4d25a1bed9197e0d40384526 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_0286 840ab7cd4d25a1bed9197e0d40384526 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_0286 840ab7cd4d25a1bed9197e0d40384526 300 Gene3D G3DSA:3.40.190.10 162 261 2.3E-53 T 14-10-2018 MCR_0286 840ab7cd4d25a1bed9197e0d40384526 300 Pfam PF03466 LysR substrate binding domain 94 293 6.3E-35 T 14-10-2018 IPR005119 LysR, substrate-binding MCR_0286 840ab7cd4d25a1bed9197e0d40384526 300 SUPERFAMILY SSF53850 94 294 1.47E-30 T 14-10-2018 MCR_0286 840ab7cd4d25a1bed9197e0d40384526 300 SUPERFAMILY SSF46785 3 85 6.35E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0286 840ab7cd4d25a1bed9197e0d40384526 300 Gene3D G3DSA:3.40.190.10 94 286 2.3E-53 T 14-10-2018 MCR_0682 f09d384ee2897e49f2c63a7a9b853405 301 Pfam PF01435 Peptidase family M48 84 298 1.0E-38 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MCR_0682 f09d384ee2897e49f2c63a7a9b853405 301 Hamap MF_00188 Protease HtpX [htpX]. 1 299 24.774 T 14-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 MCR_0682 f09d384ee2897e49f2c63a7a9b853405 301 Gene3D G3DSA:3.30.2010.10 74 167 4.9E-33 T 14-10-2018 MCR_1438 f6ad310c30f2f18c0bf13669d31d87bc 211 Pfam PF01202 Shikimate kinase 34 189 6.2E-53 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MCR_1438 f6ad310c30f2f18c0bf13669d31d87bc 211 Gene3D G3DSA:3.40.50.300 26 207 4.1E-58 T 14-10-2018 MCR_1438 f6ad310c30f2f18c0bf13669d31d87bc 211 SUPERFAMILY SSF52540 28 189 2.1E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1438 f6ad310c30f2f18c0bf13669d31d87bc 211 ProSitePatterns PS01128 Shikimate kinase signature. 81 106 - T 14-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MCR_1438 f6ad310c30f2f18c0bf13669d31d87bc 211 PRINTS PR01100 Shikimate kinase family signature 52 65 1.3E-23 T 14-10-2018 MCR_1438 f6ad310c30f2f18c0bf13669d31d87bc 211 PRINTS PR01100 Shikimate kinase family signature 98 107 1.3E-23 T 14-10-2018 MCR_1438 f6ad310c30f2f18c0bf13669d31d87bc 211 PRINTS PR01100 Shikimate kinase family signature 118 135 1.3E-23 T 14-10-2018 MCR_1438 f6ad310c30f2f18c0bf13669d31d87bc 211 PRINTS PR01100 Shikimate kinase family signature 28 43 1.3E-23 T 14-10-2018 MCR_1438 f6ad310c30f2f18c0bf13669d31d87bc 211 PRINTS PR01100 Shikimate kinase family signature 80 88 1.3E-23 T 14-10-2018 MCR_1438 f6ad310c30f2f18c0bf13669d31d87bc 211 Hamap MF_00109 Shikimate kinase [aroK]. 25 190 28.941 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MCR_1201 faffbd5c0f9d6715dedac4eb86efa172 158 Gene3D G3DSA:1.10.10.10 2 64 1.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_1201 faffbd5c0f9d6715dedac4eb86efa172 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 6.2E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MCR_1201 faffbd5c0f9d6715dedac4eb86efa172 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 6.2E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MCR_1201 faffbd5c0f9d6715dedac4eb86efa172 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 6.2E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MCR_1201 faffbd5c0f9d6715dedac4eb86efa172 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 57 5.1E-17 T 14-10-2018 MCR_1201 faffbd5c0f9d6715dedac4eb86efa172 158 Gene3D G3DSA:3.30.70.920 65 148 5.2E-25 T 14-10-2018 MCR_1201 faffbd5c0f9d6715dedac4eb86efa172 158 Pfam PF01037 Lrp/AsnC ligand binding domain 76 151 3.4E-21 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MCR_1201 faffbd5c0f9d6715dedac4eb86efa172 158 SMART SM00344 10 120 6.9E-39 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MCR_1201 faffbd5c0f9d6715dedac4eb86efa172 158 SUPERFAMILY SSF54909 73 156 9.39E-19 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MCR_1201 faffbd5c0f9d6715dedac4eb86efa172 158 SUPERFAMILY SSF46785 10 70 2.5E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_1503 7e7c2e18d26bb4ec7681d5c19d08485e 185 Pfam PF01807 CHC2 zinc finger 121 181 1.3E-14 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MCR_1503 7e7c2e18d26bb4ec7681d5c19d08485e 185 SMART SM00400 128 182 2.9E-12 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MCR_1503 7e7c2e18d26bb4ec7681d5c19d08485e 185 Gene3D G3DSA:3.90.580.10 97 184 3.8E-18 T 14-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 MCR_1503 7e7c2e18d26bb4ec7681d5c19d08485e 185 SUPERFAMILY SSF57783 109 181 9.64E-21 T 14-10-2018 MCR_1536 b1b54d352aa68b20dc7b3b6990a54b92 112 SMART SM00938 4 105 1.4E-67 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MCR_1536 b1b54d352aa68b20dc7b3b6990a54b92 112 SUPERFAMILY SSF54913 1 112 5.4E-46 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MCR_1536 b1b54d352aa68b20dc7b3b6990a54b92 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.3E-44 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MCR_1536 b1b54d352aa68b20dc7b3b6990a54b92 112 PRINTS PR00340 P-II protein signature 83 103 2.7E-43 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MCR_1536 b1b54d352aa68b20dc7b3b6990a54b92 112 PRINTS PR00340 P-II protein signature 52 75 2.7E-43 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MCR_1536 b1b54d352aa68b20dc7b3b6990a54b92 112 PRINTS PR00340 P-II protein signature 23 41 2.7E-43 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MCR_1536 b1b54d352aa68b20dc7b3b6990a54b92 112 PRINTS PR00340 P-II protein signature 2 17 2.7E-43 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MCR_1536 b1b54d352aa68b20dc7b3b6990a54b92 112 PIRSF PIRSF039144 1 112 3.7E-55 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MCR_1536 b1b54d352aa68b20dc7b3b6990a54b92 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 MCR_1536 b1b54d352aa68b20dc7b3b6990a54b92 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 14-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 MCR_1536 b1b54d352aa68b20dc7b3b6990a54b92 112 Gene3D G3DSA:3.30.70.120 1 112 1.0E-47 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MCR_0651 5851f2495842f9e5f0ea481f66252dcc 225 Pfam PF00005 ABC transporter 24 173 6.7E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0651 5851f2495842f9e5f0ea481f66252dcc 225 SMART SM00382 33 222 2.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0651 5851f2495842f9e5f0ea481f66252dcc 225 Gene3D G3DSA:3.40.50.300 1 225 3.6E-66 T 14-10-2018 MCR_0651 5851f2495842f9e5f0ea481f66252dcc 225 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 4 223 1.3E-96 T 14-10-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0016020|GO:0044873 MCR_0651 5851f2495842f9e5f0ea481f66252dcc 225 SUPERFAMILY SSF52540 4 223 6.51E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0651 5851f2495842f9e5f0ea481f66252dcc 225 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1028 4e76ed8217586b34eef9fbb8e7e9b0a3 345 SUPERFAMILY SSF51569 1 328 2.78E-103 T 14-10-2018 MCR_1028 4e76ed8217586b34eef9fbb8e7e9b0a3 345 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 328 2.5E-94 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MCR_1028 4e76ed8217586b34eef9fbb8e7e9b0a3 345 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 327 4.7E-91 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MCR_1028 4e76ed8217586b34eef9fbb8e7e9b0a3 345 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MCR_1028 4e76ed8217586b34eef9fbb8e7e9b0a3 345 Gene3D G3DSA:3.20.20.70 1 345 2.5E-151 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1028 4e76ed8217586b34eef9fbb8e7e9b0a3 345 PIRSF PIRSF001359 1 329 1.2E-80 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MCR_1028 4e76ed8217586b34eef9fbb8e7e9b0a3 345 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 344 1.5E-191 T 14-10-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 MCR_0417 f5213162e68d0f95365685f0095186cb 145 Pfam PF03653 Uncharacterised protein family (UPF0093) 4 145 5.7E-54 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 MCR_0417 f5213162e68d0f95365685f0095186cb 145 PIRSF PIRSF004638 1 145 1.3E-56 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 MCR_0417 f5213162e68d0f95365685f0095186cb 145 TIGRFAM TIGR00701 TIGR00701: TIGR00701 family protein 6 145 2.8E-45 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 MCR_0301 e5733f547d667dbf0f6f2a4aebd121ca 269 Gene3D G3DSA:1.20.120.1760 36 205 2.5E-12 T 14-10-2018 MCR_0301 e5733f547d667dbf0f6f2a4aebd121ca 269 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 85 107 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MCR_0301 e5733f547d667dbf0f6f2a4aebd121ca 269 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 49 215 1.1E-36 T 14-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 MCR_0301 e5733f547d667dbf0f6f2a4aebd121ca 269 Pfam PF01066 CDP-alcohol phosphatidyltransferase 44 107 2.0E-14 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MCR_1844 3696bd98f8a3bb9b567d24bd499487d2 149 Gene3D G3DSA:2.40.50.140 85 147 1.4E-5 T 14-10-2018 MCR_1844 3696bd98f8a3bb9b567d24bd499487d2 149 Pfam PF01957 NfeD-like C-terminal, partner-binding 7 148 1.4E-10 T 14-10-2018 IPR002810 NfeD-like, C-terminal domain MCR_1195 b98e43414d712cd8de83bda0c9f57081 82 SUPERFAMILY SSF53383 4 73 1.36E-10 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_1195 b98e43414d712cd8de83bda0c9f57081 82 Gene3D G3DSA:3.90.1150.10 1 38 1.8E-6 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_0010 7ae8f58a1adfcb64953e35dc0ab949c6 119 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 13 112 9.7E-26 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MCR_0010 7ae8f58a1adfcb64953e35dc0ab949c6 119 Gene3D G3DSA:3.10.50.40 1 113 9.6E-38 T 14-10-2018 MCR_0010 7ae8f58a1adfcb64953e35dc0ab949c6 119 SUPERFAMILY SSF54534 4 114 3.93E-33 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 Gene3D G3DSA:3.30.390.30 344 456 5.2E-48 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 Gene3D G3DSA:3.50.50.60 5 324 8.3E-115 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 Gene3D G3DSA:3.50.50.60 149 266 8.3E-115 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 324 4.9E-66 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 3 456 3.6E-200 T 14-10-2018 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 SUPERFAMILY SSF55424 343 456 3.44E-35 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 455 2.1E-35 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PIRSF PIRSF000350 1 453 6.2E-90 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 5.7E-29 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 5.7E-29 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.7E-29 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 288 310 5.7E-29 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 275 5.7E-29 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 5.2E-65 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 5.2E-65 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 5.2E-65 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 5.2E-65 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 5.2E-65 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 260 274 5.2E-65 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 303 310 5.2E-65 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 5.2E-65 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 5.2E-65 T 14-10-2018 MCR_0260 45aa5c33babbb12d28653b54241bbf5a 456 SUPERFAMILY SSF51905 3 376 2.16E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0521 5a5350550f5b7a610072d0df1005239d 112 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 48 66 5.6E-23 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 MCR_0521 5a5350550f5b7a610072d0df1005239d 112 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 29 46 5.6E-23 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 MCR_0521 5a5350550f5b7a610072d0df1005239d 112 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 71 91 5.6E-23 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 MCR_0521 5a5350550f5b7a610072d0df1005239d 112 SUPERFAMILY SSF53335 2 95 3.79E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0521 5a5350550f5b7a610072d0df1005239d 112 Gene3D G3DSA:3.40.50.150 1 111 1.2E-31 T 14-10-2018 MCR_0521 5a5350550f5b7a610072d0df1005239d 112 Pfam PF01555 DNA methylase 5 87 3.0E-27 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 MCR_1307 a0170f2d91e32a995744f6aafbf017b8 477 Gene3D G3DSA:1.10.3720.10 255 462 6.7E-19 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1307 a0170f2d91e32a995744f6aafbf017b8 477 SUPERFAMILY SSF161098 256 457 4.03E-19 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1307 a0170f2d91e32a995744f6aafbf017b8 477 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 275 469 4.3E-34 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_0597 1e7232310daadc73cf520c39b564957a 178 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 19 174 34.454 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MCR_0597 1e7232310daadc73cf520c39b564957a 178 Gene3D G3DSA:3.30.1330.50 16 178 3.4E-64 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MCR_0597 1e7232310daadc73cf520c39b564957a 178 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 20 174 4.1E-65 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MCR_0597 1e7232310daadc73cf520c39b564957a 178 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 53 68 - T 14-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MCR_0597 1e7232310daadc73cf520c39b564957a 178 SUPERFAMILY SSF69765 17 174 9.16E-64 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MCR_0597 1e7232310daadc73cf520c39b564957a 178 Pfam PF02542 YgbB family 19 172 2.8E-63 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MCR_1616 ca10b329502f89f20a5f69375051d11a 382 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 189 203 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1616 ca10b329502f89f20a5f69375051d11a 382 SUPERFAMILY SSF55120 143 368 5.12E-55 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1616 ca10b329502f89f20a5f69375051d11a 382 Pfam PF00849 RNA pseudouridylate synthase 152 311 2.1E-30 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1616 ca10b329502f89f20a5f69375051d11a 382 SUPERFAMILY SSF55174 71 122 7.65E-9 T 14-10-2018 MCR_1616 ca10b329502f89f20a5f69375051d11a 382 Gene3D G3DSA:3.10.290.10 61 124 1.9E-16 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MCR_1616 ca10b329502f89f20a5f69375051d11a 382 Pfam PF01479 S4 domain 72 118 3.8E-7 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1616 ca10b329502f89f20a5f69375051d11a 382 Gene3D G3DSA:3.30.2350.10 142 374 5.3E-63 T 14-10-2018 MCR_1616 ca10b329502f89f20a5f69375051d11a 382 SMART SM00363 72 138 0.0051 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1616 ca10b329502f89f20a5f69375051d11a 382 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 68 371 1.8E-66 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1194 1d484c4dd75575608274ceaea4a69e47 61 Pfam PF03884 DNA gyrase inhibitor YacG 7 54 4.0E-21 T 14-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 MCR_1194 1d484c4dd75575608274ceaea4a69e47 61 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 2 56 16.864 T 14-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 MCR_1194 1d484c4dd75575608274ceaea4a69e47 61 Gene3D G3DSA:3.30.50.10 1 60 8.5E-20 T 14-10-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 Reactome: R-HSA-383280 MCR_1194 1d484c4dd75575608274ceaea4a69e47 61 SUPERFAMILY SSF57716 3 56 1.57E-17 T 14-10-2018 MCR_1781 44b14b773e992b6d644c7e399a6b6535 298 Pfam PF11227 Protein of unknown function (DUF3025) 71 291 4.2E-77 T 14-10-2018 IPR021390 Protein of unknown function DUF3025 MCR_1794 e9c335f02c7b4cae1d8be771b8f85fb5 369 Pfam PF13391 HNH endonuclease 257 312 7.5E-5 T 14-10-2018 IPR003615 HNH nuclease MCR_1207 9772f32a226186f8fdeee33324b15838 246 SMART SM00382 32 225 1.0E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1207 9772f32a226186f8fdeee33324b15838 246 Gene3D G3DSA:3.40.50.300 1 219 2.6E-56 T 14-10-2018 MCR_1207 9772f32a226186f8fdeee33324b15838 246 SUPERFAMILY SSF52540 3 210 2.28E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1207 9772f32a226186f8fdeee33324b15838 246 Pfam PF00005 ABC transporter 24 162 1.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1207 9772f32a226186f8fdeee33324b15838 246 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0032 dc1b01310bf1df3ebe1dc7338db592e0 158 Pfam PF13279 Thioesterase-like superfamily 33 135 6.6E-17 T 14-10-2018 MCR_0032 dc1b01310bf1df3ebe1dc7338db592e0 158 Gene3D G3DSA:3.10.129.10 14 155 2.2E-38 T 14-10-2018 MCR_0032 dc1b01310bf1df3ebe1dc7338db592e0 158 SUPERFAMILY SSF54637 21 152 2.79E-31 T 14-10-2018 IPR029069 HotDog domain superfamily MCR_1169 a8a5fdb4884dfe825382de866afdc513 277 Gene3D G3DSA:1.25.40.10 42 233 2.0E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_1169 a8a5fdb4884dfe825382de866afdc513 277 SUPERFAMILY SSF48452 110 215 4.07E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_1169 a8a5fdb4884dfe825382de866afdc513 277 Pfam PF09976 Tetratricopeptide repeat-like domain 23 230 1.6E-31 T 14-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 MCR_1661 a34b630934324f70808d98785bfb99e5 181 Pfam PF03625 Domain of unknown function DUF302 89 149 5.2E-18 T 14-10-2018 IPR005180 Domain of unknown function DUF302 MCR_1661 a34b630934324f70808d98785bfb99e5 181 SUPERFAMILY SSF103247 60 178 1.44E-30 T 14-10-2018 IPR035923 TT1751-like domain superfamily MCR_1661 a34b630934324f70808d98785bfb99e5 181 Gene3D G3DSA:3.30.310.70 53 181 3.1E-17 T 14-10-2018 IPR035923 TT1751-like domain superfamily MCR_0555 9adb3ac4bb1837242bbc8661ea2341aa 653 Pfam PF00085 Thioredoxin 558 651 2.0E-7 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 MCR_0555 9adb3ac4bb1837242bbc8661ea2341aa 653 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 262 472 2.8E-14 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MCR_0555 9adb3ac4bb1837242bbc8661ea2341aa 653 SUPERFAMILY SSF52833 545 651 5.62E-16 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0555 9adb3ac4bb1837242bbc8661ea2341aa 653 Gene3D G3DSA:2.60.40.1250 24 166 2.8E-32 T 14-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily MCR_0555 9adb3ac4bb1837242bbc8661ea2341aa 653 Gene3D G3DSA:3.40.30.10 538 652 7.7E-17 T 14-10-2018 MCR_0555 9adb3ac4bb1837242bbc8661ea2341aa 653 SUPERFAMILY SSF74863 32 149 8.5E-26 T 14-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily MCR_0555 9adb3ac4bb1837242bbc8661ea2341aa 653 Pfam PF11412 Disulphide bond corrector protein DsbC 33 148 9.7E-25 T 14-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MCR_1082 7a1500b755644101950e62f4190f6dec 542 PIRSF PIRSF000850 83 139 11.0 T 14-10-2018 MCR_1082 7a1500b755644101950e62f4190f6dec 542 PIRSF PIRSF000850 267 496 4.0E-6 T 14-10-2018 MCR_1082 7a1500b755644101950e62f4190f6dec 542 SUPERFAMILY SSF56024 61 252 1.31E-37 T 14-10-2018 MCR_1082 7a1500b755644101950e62f4190f6dec 542 SMART SM00155 431 458 0.044 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MCR_1082 7a1500b755644101950e62f4190f6dec 542 SMART SM00155 181 208 7.1E-4 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MCR_1082 7a1500b755644101950e62f4190f6dec 542 Gene3D G3DSA:3.30.870.10 315 503 1.6E-35 T 14-10-2018 MCR_1082 7a1500b755644101950e62f4190f6dec 542 SUPERFAMILY SSF56024 333 482 9.87E-27 T 14-10-2018 MCR_1082 7a1500b755644101950e62f4190f6dec 542 Pfam PF13091 PLD-like domain 96 237 1.2E-12 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MCR_1082 7a1500b755644101950e62f4190f6dec 542 Pfam PF13091 PLD-like domain 338 481 4.1E-21 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MCR_1082 7a1500b755644101950e62f4190f6dec 542 Gene3D G3DSA:3.30.870.10 69 261 2.4E-34 T 14-10-2018 MCR_1423 a7e5885b787668aa311ffffaaebbdd25 185 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 106 146 2.0E-8 T 14-10-2018 IPR018637 Domain of unknown function DUF2059 MCR_0795 d3de92ee42edf0e40976c3c6d4b69feb 519 Gene3D G3DSA:1.20.58.100 422 501 5.3E-9 T 14-10-2018 MCR_0795 d3de92ee42edf0e40976c3c6d4b69feb 519 Gene3D G3DSA:3.90.700.10 237 346 2.2E-146 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0795 d3de92ee42edf0e40976c3c6d4b69feb 519 SUPERFAMILY SSF56425 228 340 1.15E-37 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0795 d3de92ee42edf0e40976c3c6d4b69feb 519 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 5 503 1.5E-159 T 14-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 MCR_0795 d3de92ee42edf0e40976c3c6d4b69feb 519 Gene3D G3DSA:3.50.50.60 7 392 2.2E-146 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0795 d3de92ee42edf0e40976c3c6d4b69feb 519 SUPERFAMILY SSF51905 2 417 1.18E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MCR_0795 d3de92ee42edf0e40976c3c6d4b69feb 519 Pfam PF00890 FAD binding domain 7 380 1.8E-90 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_0795 d3de92ee42edf0e40976c3c6d4b69feb 519 SUPERFAMILY SSF46977 430 501 8.63E-9 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 SUPERFAMILY SSF52029 183 375 1.92E-83 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 SUPERFAMILY SSF54849 136 203 8.24E-22 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 PRINTS PR00298 60kDa chaperonin signature 26 52 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 PRINTS PR00298 60kDa chaperonin signature 82 109 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 PRINTS PR00298 60kDa chaperonin signature 349 374 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 PRINTS PR00298 60kDa chaperonin signature 397 418 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 PRINTS PR00298 60kDa chaperonin signature 267 290 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 Gene3D G3DSA:3.50.7.10 172 378 1.0E-240 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 Hamap MF_00600 60 kDa chaperonin [groL]. 1 544 41.619 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 524 6.6E-99 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 Gene3D G3DSA:1.10.560.10 7 520 1.0E-240 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 SUPERFAMILY SSF48592 6 520 3.5E-79 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 6.0E-256 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 ProSitePatterns PS00296 Chaperonins cpn60 signature. 404 415 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MCR_1493 7409e78f991fa34b1524ac0ebf315a58 545 Gene3D G3DSA:3.30.260.10 137 409 1.0E-240 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MCR_1236 a37734bc45d2fa4278235d7fd1d3940c 196 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 12 168 5.1E-40 T 14-10-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 MCR_1236 a37734bc45d2fa4278235d7fd1d3940c 196 Gene3D G3DSA:3.40.30.10 30 177 8.4E-30 T 14-10-2018 MCR_1236 a37734bc45d2fa4278235d7fd1d3940c 196 SUPERFAMILY SSF52833 46 167 1.96E-26 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_1236 a37734bc45d2fa4278235d7fd1d3940c 196 ProSitePatterns PS00194 Thioredoxin family active site. 71 89 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MCR_1236 a37734bc45d2fa4278235d7fd1d3940c 196 Pfam PF08534 Redoxin 41 159 8.1E-13 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MCR_0420 039950d237e466357848a3c5907bd47e 346 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 220 314 3.8E-17 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MCR_0420 039950d237e466357848a3c5907bd47e 346 TIGRFAM TIGR00433 bioB: biotin synthase 13 314 4.8E-113 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MCR_0420 039950d237e466357848a3c5907bd47e 346 Pfam PF04055 Radical SAM superfamily 48 204 5.2E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MCR_0420 039950d237e466357848a3c5907bd47e 346 SMART SM00729 41 254 5.0E-35 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MCR_0420 039950d237e466357848a3c5907bd47e 346 SUPERFAMILY SSF102114 5 316 2.22E-79 T 14-10-2018 MCR_0420 039950d237e466357848a3c5907bd47e 346 Gene3D G3DSA:3.20.20.70 4 319 1.1E-115 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0420 039950d237e466357848a3c5907bd47e 346 Hamap MF_01694 Biotin synthase [bioB]. 3 317 40.515 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MCR_0420 039950d237e466357848a3c5907bd47e 346 SMART SM00876 220 316 2.3E-38 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MCR_0420 039950d237e466357848a3c5907bd47e 346 PIRSF PIRSF001619 1 322 1.9E-128 T 14-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MCR_1604 8765705e0816d1affc19fe13155ef5c3 190 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 3 180 35.076 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MCR_1604 8765705e0816d1affc19fe13155ef5c3 190 Gene3D G3DSA:3.40.50.1470 1 190 2.2E-69 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 MCR_1604 8765705e0816d1affc19fe13155ef5c3 190 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 187 1.4E-62 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MCR_1604 8765705e0816d1affc19fe13155ef5c3 190 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 16 29 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MCR_1604 8765705e0816d1affc19fe13155ef5c3 190 Pfam PF01195 Peptidyl-tRNA hydrolase 5 187 2.6E-53 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MCR_1604 8765705e0816d1affc19fe13155ef5c3 190 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 110 120 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MCR_1604 8765705e0816d1affc19fe13155ef5c3 190 SUPERFAMILY SSF53178 3 189 6.67E-67 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 Hamap MF_00268 Protein RecA [recA]. 5 330 51.685 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 SUPERFAMILY SSF54752 270 325 8.63E-20 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 ProSitePatterns PS00321 recA signature. 214 222 - T 14-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 SUPERFAMILY SSF52540 4 268 1.07E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 Gene3D G3DSA:3.30.250.10 269 327 4.0E-23 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 SMART SM00382 58 229 2.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 PRINTS PR00142 RecA protein signature 298 315 1.1E-83 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 PRINTS PR00142 RecA protein signature 166 195 1.1E-83 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 PRINTS PR00142 RecA protein signature 211 239 1.1E-83 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 PRINTS PR00142 RecA protein signature 128 157 1.1E-83 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 PRINTS PR00142 RecA protein signature 244 273 1.1E-83 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 PRINTS PR00142 RecA protein signature 94 123 1.1E-83 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 Gene3D G3DSA:3.40.50.300 28 268 3.7E-85 T 14-10-2018 MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 Pfam PF00154 recA bacterial DNA recombination protein 7 269 1.4E-148 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MCR_0311 d007b90c0aca2866a5481e492bf17a6c 349 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 325 1.7E-170 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MCR_1886 bb3cbc620579eee8b8410cc3a318140c 594 Pfam PF04087 Domain of unknown function (DUF389) 277 412 1.0E-31 T 14-10-2018 IPR005240 Protein of unknown function DUF389 MCR_1521 ffb036a34d3162e3e36fc3f1daf03df1 287 SUPERFAMILY SSF69360 83 205 3.14E-11 T 14-10-2018 MCR_1521 ffb036a34d3162e3e36fc3f1daf03df1 287 Pfam PF14903 WG containing repeat 191 221 5.4E-10 T 14-10-2018 IPR032774 WG containing repeat MCR_1521 ffb036a34d3162e3e36fc3f1daf03df1 287 Pfam PF14903 WG containing repeat 88 122 1.1E-8 T 14-10-2018 IPR032774 WG containing repeat MCR_1521 ffb036a34d3162e3e36fc3f1daf03df1 287 Pfam PF14903 WG containing repeat 236 260 1.5E-6 T 14-10-2018 IPR032774 WG containing repeat MCR_1521 ffb036a34d3162e3e36fc3f1daf03df1 287 Pfam PF14903 WG containing repeat 122 156 2.9E-10 T 14-10-2018 IPR032774 WG containing repeat MCR_1521 ffb036a34d3162e3e36fc3f1daf03df1 287 Pfam PF14903 WG containing repeat 156 191 1.6E-10 T 14-10-2018 IPR032774 WG containing repeat MCR_0860 40adea4ff2d913ed2a3d12ffa78052a1 343 Pfam PF01471 Putative peptidoglycan binding domain 85 124 1.5E-7 T 14-10-2018 IPR002477 Peptidoglycan binding-like MCR_0860 40adea4ff2d913ed2a3d12ffa78052a1 343 Gene3D G3DSA:2.40.440.10 154 343 2.2E-40 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like MCR_0860 40adea4ff2d913ed2a3d12ffa78052a1 343 SUPERFAMILY SSF47090 61 130 1.02E-12 T 14-10-2018 IPR036365 PGBD-like superfamily MCR_0860 40adea4ff2d913ed2a3d12ffa78052a1 343 Gene3D G3DSA:1.10.101.10 68 135 2.9E-9 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 MCR_0860 40adea4ff2d913ed2a3d12ffa78052a1 343 SUPERFAMILY SSF141523 214 342 7.59E-27 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like MCR_0860 40adea4ff2d913ed2a3d12ffa78052a1 343 Pfam PF03734 L,D-transpeptidase catalytic domain 215 342 9.4E-19 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MCR_1600 6268e9afd26aa114c293ff9e84348cac 91 SUPERFAMILY SSF55229 38 90 1.16E-11 T 14-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 MCR_1600 6268e9afd26aa114c293ff9e84348cac 91 Gene3D G3DSA:3.30.1070.10 22 89 3.5E-19 T 14-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 MCR_1600 6268e9afd26aa114c293ff9e84348cac 91 Pfam PF03776 Septum formation topological specificity factor MinE 18 88 5.1E-20 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MCR_1600 6268e9afd26aa114c293ff9e84348cac 91 Hamap MF_00262 Cell division topological specificity factor [minE]. 5 90 14.242 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MCR_1600 6268e9afd26aa114c293ff9e84348cac 91 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 16 89 8.9E-18 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MCR_1363 391fec097e7c7bcf9a92eaf16c3cf226 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1363 391fec097e7c7bcf9a92eaf16c3cf226 264 Pfam PF00005 ABC transporter 22 177 2.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1363 391fec097e7c7bcf9a92eaf16c3cf226 264 SMART SM00382 31 228 1.3E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1363 391fec097e7c7bcf9a92eaf16c3cf226 264 SUPERFAMILY SSF52540 18 229 1.96E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1363 391fec097e7c7bcf9a92eaf16c3cf226 264 Gene3D G3DSA:3.40.50.300 1 261 2.9E-55 T 14-10-2018 MCR_0554 a2fe09d2f85217e171af78d9b6dde942 42 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 29 2.7E-12 T 14-10-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 MCR_0554 a2fe09d2f85217e171af78d9b6dde942 42 Pfam PF08173 Membrane bound YbgT-like protein 1 26 2.6E-12 T 14-10-2018 IPR012994 Membrane bound YbgT-like MCR_0136 893ca18600514fb2302fc6f1b23b617f 278 Pfam PF03781 Sulfatase-modifying factor enzyme 1 46 277 2.0E-36 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 MCR_0136 893ca18600514fb2302fc6f1b23b617f 278 Gene3D G3DSA:3.90.1580.10 32 278 3.5E-43 T 14-10-2018 MCR_0136 893ca18600514fb2302fc6f1b23b617f 278 SUPERFAMILY SSF56436 43 278 4.24E-45 T 14-10-2018 IPR016187 C-type lectin fold MCR_1068 0d1843820c5cb4916622782ff0fc712b 166 Pfam PF00578 AhpC/TSA family 11 140 3.1E-23 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MCR_1068 0d1843820c5cb4916622782ff0fc712b 166 SUPERFAMILY SSF52833 11 163 1.45E-33 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_1068 0d1843820c5cb4916622782ff0fc712b 166 Gene3D G3DSA:3.40.30.10 9 165 2.1E-33 T 14-10-2018 MCR_1251 1a87543a7a5f6e4edd4a94e0bdf6a8a9 361 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 76 89 - T 14-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 MCR_1251 1a87543a7a5f6e4edd4a94e0bdf6a8a9 361 SUPERFAMILY SSF55120 10 352 5.18E-77 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1251 1a87543a7a5f6e4edd4a94e0bdf6a8a9 361 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 4 357 24.259 T 14-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1251 1a87543a7a5f6e4edd4a94e0bdf6a8a9 361 Gene3D G3DSA:3.30.2350.20 16 350 3.9E-100 T 14-10-2018 MCR_1251 1a87543a7a5f6e4edd4a94e0bdf6a8a9 361 Gene3D G3DSA:3.30.2340.10 175 317 3.9E-100 T 14-10-2018 MCR_1251 1a87543a7a5f6e4edd4a94e0bdf6a8a9 361 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 17 175 7.3E-35 T 14-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1251 1a87543a7a5f6e4edd4a94e0bdf6a8a9 361 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 209 349 3.6E-18 T 14-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0025 e9150c773dfc1e1e8a10ba01488e842f 316 Gene3D G3DSA:1.20.120.920 110 313 4.0E-64 T 14-10-2018 MCR_0025 e9150c773dfc1e1e8a10ba01488e842f 316 Pfam PF01867 CRISPR associated protein Cas1 27 287 1.6E-8 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MCR_0025 e9150c773dfc1e1e8a10ba01488e842f 316 Gene3D G3DSA:3.100.10.20 11 109 6.4E-45 T 14-10-2018 MCR_0025 e9150c773dfc1e1e8a10ba01488e842f 316 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 19 288 4.1E-54 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MCR_0025 e9150c773dfc1e1e8a10ba01488e842f 316 TIGRFAM TIGR03637 cas1_YPEST: CRISPR-associated endonuclease Cas1, subtype I-F/YPEST 12 308 1.1E-132 T 14-10-2018 IPR019857 CRISPR-associated protein Cas1, YPEST subtype GO:0004520|GO:0043571|GO:0046872 MCR_1514 cfb040c7eb9f488b1cab343668aac3ba 347 Pfam PF13173 AAA domain 33 171 2.2E-6 T 14-10-2018 MCR_1514 cfb040c7eb9f488b1cab343668aac3ba 347 Gene3D G3DSA:3.40.50.300 7 189 5.1E-22 T 14-10-2018 MCR_1514 cfb040c7eb9f488b1cab343668aac3ba 347 SUPERFAMILY SSF52540 9 247 1.16E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1245 a924e8df1785017a83b2f59ad68b0f17 73 SMART SM00316 3 73 2.9E-4 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_1245 a924e8df1785017a83b2f59ad68b0f17 73 SUPERFAMILY SSF50249 4 71 1.2E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1245 a924e8df1785017a83b2f59ad68b0f17 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 3.1E-28 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 MCR_1245 a924e8df1785017a83b2f59ad68b0f17 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.47 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MCR_1245 a924e8df1785017a83b2f59ad68b0f17 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 71 7.5E-37 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MCR_1245 a924e8df1785017a83b2f59ad68b0f17 73 Gene3D G3DSA:2.40.50.140 2 71 7.6E-37 T 14-10-2018 MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 Pfam PF04851 Type III restriction enzyme, res subunit 49 152 2.8E-9 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 Hamap MF_00204 UvrABC system protein B [uvrB]. 39 701 42.515 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 Pfam PF00271 Helicase conserved C-terminal domain 476 580 1.2E-18 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 SMART SM00487 45 460 7.3E-26 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 Gene3D G3DSA:3.40.50.300 301 449 2.4E-51 T 14-10-2018 MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 41 699 0.0 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 Gene3D G3DSA:4.10.860.10 653 704 1.1E-9 T 14-10-2018 MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 Gene3D G3DSA:3.40.50.300 32 270 6.7E-72 T 14-10-2018 MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 SUPERFAMILY SSF52540 40 450 7.92E-139 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 SMART SM00490 495 581 4.3E-22 T 14-10-2018 IPR001650 Helicase, C-terminal MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 SUPERFAMILY SSF52540 70 615 8.78E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 Gene3D G3DSA:3.40.50.300 450 625 2.7E-48 T 14-10-2018 MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 Pfam PF12344 Ultra-violet resistance protein B 587 628 4.0E-22 T 14-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 SUPERFAMILY SSF46600 658 702 3.01E-9 T 14-10-2018 IPR036876 UVR domain superfamily MCR_0927 e33306b8bbf8240a7eb516807e7c3bc0 704 Pfam PF02151 UvrB/uvrC motif 667 700 8.9E-8 T 14-10-2018 IPR001943 UVR domain GO:0005515 MCR_1073 17ee65a42c10e3596e9a4bd7c0660581 198 PIRSF PIRSF006806 11 194 1.9E-30 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MCR_1073 17ee65a42c10e3596e9a4bd7c0660581 198 SUPERFAMILY SSF100950 14 197 2.37E-41 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MCR_1073 17ee65a42c10e3596e9a4bd7c0660581 198 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 15 190 1.3E-26 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MCR_1073 17ee65a42c10e3596e9a4bd7c0660581 198 Gene3D G3DSA:3.40.50.10420 13 198 1.3E-40 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily MCR_1073 17ee65a42c10e3596e9a4bd7c0660581 198 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 14 190 4.7E-38 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MCR_0439 2d889cf52b9c1411d4bf11c79b9724b8 786 Gene3D G3DSA:1.10.3810.10 63 258 2.1E-72 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0439 2d889cf52b9c1411d4bf11c79b9724b8 786 Pfam PF00912 Transglycosylase 69 244 3.3E-61 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0439 2d889cf52b9c1411d4bf11c79b9724b8 786 Pfam PF00905 Penicillin binding protein transpeptidase domain 430 608 2.2E-24 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MCR_0439 2d889cf52b9c1411d4bf11c79b9724b8 786 Pfam PF00905 Penicillin binding protein transpeptidase domain 665 752 1.7E-6 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MCR_0439 2d889cf52b9c1411d4bf11c79b9724b8 786 Pfam PF17092 Penicillin-binding protein OB-like domain 339 428 2.2E-15 T 14-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0439 2d889cf52b9c1411d4bf11c79b9724b8 786 SUPERFAMILY SSF56601 225 764 1.99E-115 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MCR_0439 2d889cf52b9c1411d4bf11c79b9724b8 786 Gene3D G3DSA:2.40.50.140 330 425 1.5E-19 T 14-10-2018 MCR_0439 2d889cf52b9c1411d4bf11c79b9724b8 786 SUPERFAMILY SSF53955 58 271 7.31E-74 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MCR_0439 2d889cf52b9c1411d4bf11c79b9724b8 786 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 82 758 3.0E-171 T 14-10-2018 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 432 4.9E-151 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 PRINTS PR00083 Histidinol dehydrogenase signature 257 276 3.5E-72 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 3.5E-72 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 3.5E-72 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 PRINTS PR00083 Histidinol dehydrogenase signature 326 351 3.5E-72 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 PRINTS PR00083 Histidinol dehydrogenase signature 140 166 3.5E-72 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 PRINTS PR00083 Histidinol dehydrogenase signature 367 385 3.5E-72 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 3.5E-72 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 SUPERFAMILY SSF53720 30 433 5.69E-78 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 Gene3D G3DSA:3.40.50.1980 237 355 2.0E-116 T 14-10-2018 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 PIRSF PIRSF000099 3 435 3.2E-148 T 14-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 Pfam PF00815 Histidinol dehydrogenase 28 432 1.1E-158 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 Gene3D G3DSA:3.40.50.1980 34 235 2.0E-116 T 14-10-2018 MCR_1746 694095de1b46f0bf33739c4a84cb0996 435 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 433 38.52 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MCR_0865 a5f62b7ceb8403c3eaa10605cdb14055 235 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 15 232 38.952 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MCR_0865 a5f62b7ceb8403c3eaa10605cdb14055 235 SUPERFAMILY SSF52141 12 232 2.18E-86 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MCR_0865 a5f62b7ceb8403c3eaa10605cdb14055 235 Pfam PF03167 Uracil DNA glycosylase superfamily 65 220 8.1E-21 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MCR_0865 a5f62b7ceb8403c3eaa10605cdb14055 235 Gene3D G3DSA:3.40.470.10 1 235 8.1E-95 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MCR_0865 a5f62b7ceb8403c3eaa10605cdb14055 235 SMART SM00986 60 221 6.3E-35 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MCR_0865 a5f62b7ceb8403c3eaa10605cdb14055 235 SMART SM00987 60 221 6.3E-35 T 14-10-2018 MCR_0865 a5f62b7ceb8403c3eaa10605cdb14055 235 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 16 226 2.0E-77 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MCR_0865 a5f62b7ceb8403c3eaa10605cdb14055 235 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 68 77 - T 14-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MCR_0931 8ec8f5c19b65d5eb37ab111d158de06d 341 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 114 132 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MCR_0931 8ec8f5c19b65d5eb37ab111d158de06d 341 Pfam PF01207 Dihydrouridine synthase (Dus) 34 339 1.6E-98 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MCR_0931 8ec8f5c19b65d5eb37ab111d158de06d 341 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 23 340 4.4E-113 T 14-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 MCR_0931 8ec8f5c19b65d5eb37ab111d158de06d 341 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 21 341 45.62 T 14-10-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 MCR_0931 8ec8f5c19b65d5eb37ab111d158de06d 341 PIRSF PIRSF006621 21 341 2.9E-103 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MCR_0931 8ec8f5c19b65d5eb37ab111d158de06d 341 Gene3D G3DSA:1.10.1200.80 272 341 1.3E-12 T 14-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 MCR_0931 8ec8f5c19b65d5eb37ab111d158de06d 341 SUPERFAMILY SSF51395 30 338 1.32E-86 T 14-10-2018 MCR_0931 8ec8f5c19b65d5eb37ab111d158de06d 341 Gene3D G3DSA:3.20.20.70 26 268 5.8E-77 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1416 dd16a94d8737cbe6456a9952d6343e4c 152 Gene3D G3DSA:1.20.120.10 27 152 3.0E-25 T 14-10-2018 MCR_1416 dd16a94d8737cbe6456a9952d6343e4c 152 SUPERFAMILY SSF47175 30 152 1.34E-27 T 14-10-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 MCR_1416 dd16a94d8737cbe6456a9952d6343e4c 152 Pfam PF01322 Cytochrome C' 32 150 1.3E-26 T 14-10-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 MCR_1416 dd16a94d8737cbe6456a9952d6343e4c 152 PIRSF PIRSF000027 6 152 1.6E-23 T 14-10-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 MCR_0501 20fc988cc1e8a81371ba9bf844b71192 409 SUPERFAMILY SSF103473 5 377 1.22E-26 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_0501 20fc988cc1e8a81371ba9bf844b71192 409 Gene3D G3DSA:1.20.1250.20 8 380 1.1E-26 T 14-10-2018 MCR_0501 20fc988cc1e8a81371ba9bf844b71192 409 Pfam PF07690 Major Facilitator Superfamily 20 259 2.5E-15 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MCR_1388 3f2e7153b2997b0d80ea012da685109c 568 Gene3D G3DSA:3.30.300.310 469 567 2.3E-31 T 14-10-2018 MCR_1388 3f2e7153b2997b0d80ea012da685109c 568 ProSitePatterns PS00455 Putative AMP-binding domain signature. 221 232 - T 14-10-2018 IPR020845 AMP-binding, conserved site MCR_1388 3f2e7153b2997b0d80ea012da685109c 568 Pfam PF13193 AMP-binding enzyme C-terminal domain 481 555 4.3E-20 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MCR_1388 3f2e7153b2997b0d80ea012da685109c 568 Gene3D G3DSA:3.40.50.12780 26 468 8.8E-107 T 14-10-2018 MCR_1388 3f2e7153b2997b0d80ea012da685109c 568 Pfam PF00501 AMP-binding enzyme 41 472 1.0E-103 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MCR_1388 3f2e7153b2997b0d80ea012da685109c 568 SUPERFAMILY SSF56801 23 566 6.41E-145 T 14-10-2018 MCR_1276 274c65f4c4e08485c5b1a70bd8c23742 133 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 1.2E-31 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1276 274c65f4c4e08485c5b1a70bd8c23742 133 ProSitePatterns PS01048 Ribosomal protein S6 signature. 43 52 - T 14-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 MCR_1276 274c65f4c4e08485c5b1a70bd8c23742 133 Gene3D G3DSA:3.30.70.60 1 92 1.6E-29 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MCR_1276 274c65f4c4e08485c5b1a70bd8c23742 133 Pfam PF01250 Ribosomal protein S6 3 91 1.9E-26 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1276 274c65f4c4e08485c5b1a70bd8c23742 133 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.008 T 14-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 MCR_1276 274c65f4c4e08485c5b1a70bd8c23742 133 SUPERFAMILY SSF54995 1 102 6.67E-36 T 14-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1140 e8ce2b6331afe7bebf003cf63c1a6d16 125 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 3 125 8.4E-29 T 14-10-2018 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 MCR_1140 e8ce2b6331afe7bebf003cf63c1a6d16 125 SUPERFAMILY SSF75169 2 125 1.44E-23 T 14-10-2018 IPR027396 DsrEFH-like MCR_1140 e8ce2b6331afe7bebf003cf63c1a6d16 125 Gene3D G3DSA:3.40.1260.10 1 125 1.3E-35 T 14-10-2018 IPR027396 DsrEFH-like MCR_1140 e8ce2b6331afe7bebf003cf63c1a6d16 125 Pfam PF02635 DsrE/DsrF-like family 2 125 3.0E-21 T 14-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein MCR_1174 3d05a05dfb6fcf724132887c3f70ed25 395 Gene3D G3DSA:1.10.150.530 5 80 1.3E-25 T 14-10-2018 MCR_1174 3d05a05dfb6fcf724132887c3f70ed25 395 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 19 375 72.737 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 MCR_1174 3d05a05dfb6fcf724132887c3f70ed25 395 PIRSF PIRSF006004 13 389 4.2E-146 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 MCR_1174 3d05a05dfb6fcf724132887c3f70ed25 395 Pfam PF04055 Radical SAM superfamily 128 303 1.4E-15 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MCR_1174 3d05a05dfb6fcf724132887c3f70ed25 395 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 18 380 6.3E-141 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 MCR_1174 3d05a05dfb6fcf724132887c3f70ed25 395 Gene3D G3DSA:3.20.20.70 81 360 3.3E-106 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1174 3d05a05dfb6fcf724132887c3f70ed25 395 SMART SM00729 123 347 0.0044 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MCR_1174 3d05a05dfb6fcf724132887c3f70ed25 395 SUPERFAMILY SSF102114 120 332 1.26E-15 T 14-10-2018 MCR_1786 457ca807c552d2d7a5efa775822f0b63 175 Pfam PF01029 NusB family 26 164 1.8E-25 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MCR_1786 457ca807c552d2d7a5efa775822f0b63 175 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 26 165 2.6E-29 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 MCR_1786 457ca807c552d2d7a5efa775822f0b63 175 SUPERFAMILY SSF48013 24 168 3.14E-28 T 14-10-2018 IPR035926 NusB-like superfamily MCR_1786 457ca807c552d2d7a5efa775822f0b63 175 Gene3D G3DSA:1.10.940.10 19 171 7.6E-37 T 14-10-2018 IPR035926 NusB-like superfamily MCR_1786 457ca807c552d2d7a5efa775822f0b63 175 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 23 167 17.852 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 SUPERFAMILY SSF57783 756 819 3.57E-15 T 14-10-2018 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 25 647 1.8E-240 T 14-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Gene3D G3DSA:3.40.50.140 21 180 2.6E-64 T 14-10-2018 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 330 339 2.8E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 406 422 2.8E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 504 518 2.8E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 123 136 2.8E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 208 226 2.8E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Gene3D G3DSA:1.10.290.10 296 420 8.5E-155 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Pfam PF01131 DNA topoisomerase 174 579 5.0E-125 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Gene3D G3DSA:3.30.65.10 757 819 4.8E-24 T 14-10-2018 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Gene3D G3DSA:3.30.65.10 715 756 1.2E-6 T 14-10-2018 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 SUPERFAMILY SSF57783 719 754 6.97E-6 T 14-10-2018 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 SUPERFAMILY SSF56712 23 621 1.24E-194 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Gene3D G3DSA:2.70.20.10 230 487 8.5E-155 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 SUPERFAMILY SSF57783 821 874 4.25E-17 T 14-10-2018 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 724 756 1.0E-5 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 609 634 1.3E-4 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Hamap MF_00952 DNA topoisomerase 1 [topA]. 23 746 54.162 T 14-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Gene3D G3DSA:1.10.460.10 182 585 8.5E-155 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 SMART SM00437 288 541 2.6E-114 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Pfam PF01751 Toprim domain 25 159 1.8E-31 T 14-10-2018 IPR006171 TOPRIM domain MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 SMART SM00493 23 149 3.2E-29 T 14-10-2018 IPR006171 TOPRIM domain MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Pfam PF08272 Topoisomerase I zinc-ribbon-like 770 805 6.7E-12 T 14-10-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Pfam PF08272 Topoisomerase I zinc-ribbon-like 836 874 3.3E-16 T 14-10-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 325 339 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 SMART SM00436 150 238 2.4E-47 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MCR_1685 f946a77d3bcfa032a7b4b70290a8c70f 875 Gene3D G3DSA:2.20.25.10 820 875 2.7E-21 T 14-10-2018 MCR_1012 393bbf8f8edbfad4cf769387b19b79ae 382 Gene3D G3DSA:3.10.180.10 25 177 2.6E-51 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MCR_1012 393bbf8f8edbfad4cf769387b19b79ae 382 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 36 380 3.6E-115 T 14-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 MCR_1012 393bbf8f8edbfad4cf769387b19b79ae 382 Gene3D G3DSA:3.10.180.10 178 381 7.0E-63 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MCR_1012 393bbf8f8edbfad4cf769387b19b79ae 382 PIRSF PIRSF009283 20 381 3.0E-109 T 14-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 MCR_1012 393bbf8f8edbfad4cf769387b19b79ae 382 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 183 298 1.4E-16 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MCR_1012 393bbf8f8edbfad4cf769387b19b79ae 382 SUPERFAMILY SSF54593 28 367 6.34E-80 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MCR_1012 393bbf8f8edbfad4cf769387b19b79ae 382 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 28 166 1.8E-70 T 14-10-2018 MCR_1744 305df25911cce1cedf7430ebffdcd476 508 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 287 1.4E-61 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 MCR_1744 305df25911cce1cedf7430ebffdcd476 508 SUPERFAMILY SSF117457 320 489 1.7E-63 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 MCR_1744 305df25911cce1cedf7430ebffdcd476 508 Gene3D G3DSA:3.20.130.10 309 490 5.0E-62 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 MCR_1744 305df25911cce1cedf7430ebffdcd476 508 Pfam PF05683 Fumarase C-terminus 292 491 2.9E-78 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MCR_1744 305df25911cce1cedf7430ebffdcd476 508 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 328 489 2.9E-48 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MCR_1744 305df25911cce1cedf7430ebffdcd476 508 PIRSF PIRSF001394 1 508 3.7E-219 T 14-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 MCR_1744 305df25911cce1cedf7430ebffdcd476 508 Pfam PF05681 Fumarate hydratase (Fumerase) 11 288 1.8E-101 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 MCR_0729 d2438f66f0f4e5a8d1bb8ede6dab2804 133 Gene3D G3DSA:3.10.290.10 1 112 7.4E-34 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MCR_0729 d2438f66f0f4e5a8d1bb8ede6dab2804 133 SMART SM00363 9 70 3.0E-7 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0729 d2438f66f0f4e5a8d1bb8ede6dab2804 133 PIRSF PIRSF016821 6 133 1.8E-37 T 14-10-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 MCR_0729 d2438f66f0f4e5a8d1bb8ede6dab2804 133 SUPERFAMILY SSF55174 6 107 2.62E-23 T 14-10-2018 MCR_0729 d2438f66f0f4e5a8d1bb8ede6dab2804 133 Pfam PF01479 S4 domain 10 54 2.7E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_0043 0c355d3a895659142b9b206362086eb0 181 SUPERFAMILY SSF69118 1 180 4.58E-45 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MCR_0043 0c355d3a895659142b9b206362086eb0 181 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 57 90 2.9E-9 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MCR_0043 0c355d3a895659142b9b206362086eb0 181 Pfam PF02627 Carboxymuconolactone decarboxylase family 41 106 4.8E-8 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MCR_0043 0c355d3a895659142b9b206362086eb0 181 Gene3D G3DSA:1.20.1290.10 13 180 1.3E-44 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MCR_0705 b7c695014a833e119464cefc35948ca3 202 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 117 17.337 T 14-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 MCR_0705 b7c695014a833e119464cefc35948ca3 202 Gene3D G3DSA:1.20.58.1610 1 117 1.5E-33 T 14-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0705 b7c695014a833e119464cefc35948ca3 202 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 116 4.9E-29 T 14-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0426 a0b87f4e59ae120516019bb60d71791b 122 Gene3D G3DSA:3.30.110.70 4 109 1.2E-31 T 14-10-2018 MCR_0426 a0b87f4e59ae120516019bb60d71791b 122 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 3 105 23.473 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 MCR_0426 a0b87f4e59ae120516019bb60d71791b 122 Pfam PF01906 Putative heavy-metal-binding 3 105 1.3E-35 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 MCR_0426 a0b87f4e59ae120516019bb60d71791b 122 SUPERFAMILY SSF117782 3 107 8.5E-35 T 14-10-2018 IPR035439 UPF0145 domain superfamily MCR_0488 4ab37d5e6a767bc08dfba9a1972bc366 433 PIRSF PIRSF000098 2 432 2.0E-150 T 14-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MCR_0488 4ab37d5e6a767bc08dfba9a1972bc366 433 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 127 4.3E-17 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MCR_0488 4ab37d5e6a767bc08dfba9a1972bc366 433 SUPERFAMILY SSF55021 351 422 2.27E-12 T 14-10-2018 MCR_0488 4ab37d5e6a767bc08dfba9a1972bc366 433 SUPERFAMILY SSF51735 3 156 9.32E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0488 4ab37d5e6a767bc08dfba9a1972bc366 433 Gene3D G3DSA:3.30.360.10 134 346 1.2E-150 T 14-10-2018 MCR_0488 4ab37d5e6a767bc08dfba9a1972bc366 433 Pfam PF01842 ACT domain 352 418 6.5E-12 T 14-10-2018 IPR002912 ACT domain MCR_0488 4ab37d5e6a767bc08dfba9a1972bc366 433 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 181 203 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MCR_0488 4ab37d5e6a767bc08dfba9a1972bc366 433 Gene3D G3DSA:3.30.70.260 347 420 1.2E-150 T 14-10-2018 MCR_0488 4ab37d5e6a767bc08dfba9a1972bc366 433 Pfam PF00742 Homoserine dehydrogenase 135 313 6.2E-61 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MCR_0488 4ab37d5e6a767bc08dfba9a1972bc366 433 SUPERFAMILY SSF55347 135 300 2.81E-50 T 14-10-2018 MCR_0488 4ab37d5e6a767bc08dfba9a1972bc366 433 Gene3D G3DSA:3.40.50.720 5 338 1.2E-150 T 14-10-2018 MCR_0713 94bb20da5291c61164159c7f0692c55a 472 Gene3D G3DSA:3.40.50.11540 92 269 8.1E-75 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0713 94bb20da5291c61164159c7f0692c55a 472 Gene3D G3DSA:1.20.1440.230 371 470 1.4E-26 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0713 94bb20da5291c61164159c7f0692c55a 472 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 87 258 2.6E-45 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0713 94bb20da5291c61164159c7f0692c55a 472 SMART SM00928 373 418 5.3E-19 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0713 94bb20da5291c61164159c7f0692c55a 472 Gene3D G3DSA:3.10.20.600 276 370 1.1E-26 T 14-10-2018 MCR_0713 94bb20da5291c61164159c7f0692c55a 472 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 386 397 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0713 94bb20da5291c61164159c7f0692c55a 472 SUPERFAMILY SSF142984 284 368 2.09E-20 T 14-10-2018 MCR_0713 94bb20da5291c61164159c7f0692c55a 472 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 376 458 2.5E-25 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0713 94bb20da5291c61164159c7f0692c55a 472 SUPERFAMILY SSF142019 46 278 1.83E-80 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0713 94bb20da5291c61164159c7f0692c55a 472 SUPERFAMILY SSF140490 370 467 4.18E-30 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0713 94bb20da5291c61164159c7f0692c55a 472 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 47 460 3.7E-170 T 14-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0817 deda65192ec1deb1ab24a765113b9b64 346 Gene3D G3DSA:3.90.1530.30 95 166 1.1E-24 T 14-10-2018 MCR_0817 deda65192ec1deb1ab24a765113b9b64 346 SUPERFAMILY SSF110849 82 182 8.37E-23 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily MCR_0817 deda65192ec1deb1ab24a765113b9b64 346 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 82 264 1.9E-49 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MCR_0817 deda65192ec1deb1ab24a765113b9b64 346 Gene3D G3DSA:1.10.10.2830 167 280 1.3E-32 T 14-10-2018 MCR_0817 deda65192ec1deb1ab24a765113b9b64 346 Pfam PF02195 ParB-like nuclease domain 84 180 2.8E-20 T 14-10-2018 IPR003115 ParB/Sulfiredoxin MCR_0817 deda65192ec1deb1ab24a765113b9b64 346 SMART SM00470 82 180 1.2E-28 T 14-10-2018 IPR003115 ParB/Sulfiredoxin MCR_0817 deda65192ec1deb1ab24a765113b9b64 346 SUPERFAMILY SSF109709 173 280 1.1E-30 T 14-10-2018 MCR_1576 0762e15fa3f07232d13ef5950eb8f3da 90 Gene3D G3DSA:2.40.50.140 7 89 7.5E-33 T 14-10-2018 MCR_1576 0762e15fa3f07232d13ef5950eb8f3da 90 Pfam PF00366 Ribosomal protein S17 15 81 5.1E-32 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1576 0762e15fa3f07232d13ef5950eb8f3da 90 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 12 81 4.0E-29 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1576 0762e15fa3f07232d13ef5950eb8f3da 90 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 12 81 2.0E-34 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1576 0762e15fa3f07232d13ef5950eb8f3da 90 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 85 23.9 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1576 0762e15fa3f07232d13ef5950eb8f3da 90 SUPERFAMILY SSF50249 13 86 7.71E-31 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1576 0762e15fa3f07232d13ef5950eb8f3da 90 PRINTS PR00973 Ribosomal protein S17 family signature 61 71 6.1E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1576 0762e15fa3f07232d13ef5950eb8f3da 90 PRINTS PR00973 Ribosomal protein S17 family signature 29 52 6.1E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1576 0762e15fa3f07232d13ef5950eb8f3da 90 PRINTS PR00973 Ribosomal protein S17 family signature 71 78 6.1E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0984 63b11229ed4e19c199d7487f4e41ab4e 145 PIRSF PIRSF000714 1 139 2.8E-48 T 14-10-2018 IPR026026 Histidine triad hydrolase, Hint-type MCR_0984 63b11229ed4e19c199d7487f4e41ab4e 145 Gene3D G3DSA:3.30.428.10 1 138 1.1E-36 T 14-10-2018 IPR036265 HIT-like superfamily MCR_0984 63b11229ed4e19c199d7487f4e41ab4e 145 Pfam PF01230 HIT domain 10 98 2.9E-11 T 14-10-2018 IPR001310 Histidine triad (HIT) protein MCR_0984 63b11229ed4e19c199d7487f4e41ab4e 145 SUPERFAMILY SSF54197 2 131 3.83E-29 T 14-10-2018 IPR036265 HIT-like superfamily MCR_1056 c6e1c88ef123b831e19dddd9ab71ec96 235 SUPERFAMILY SSF47616 110 229 3.77E-13 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MCR_1056 c6e1c88ef123b831e19dddd9ab71ec96 235 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 83 3.4E-9 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MCR_1056 c6e1c88ef123b831e19dddd9ab71ec96 235 Gene3D G3DSA:3.40.30.10 1 92 4.1E-27 T 14-10-2018 MCR_1056 c6e1c88ef123b831e19dddd9ab71ec96 235 SUPERFAMILY SSF52833 1 94 4.2E-14 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_1056 c6e1c88ef123b831e19dddd9ab71ec96 235 Gene3D G3DSA:1.20.1050.10 101 227 2.4E-15 T 14-10-2018 MCR_0544 58f6c63b061342966b25e0671d7ea75d 457 SUPERFAMILY SSF50156 224 289 8.41E-13 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 MCR_0544 58f6c63b061342966b25e0671d7ea75d 457 Gene3D G3DSA:2.30.42.10 223 311 1.2E-16 T 14-10-2018 MCR_0544 58f6c63b061342966b25e0671d7ea75d 457 SMART SM00228 213 282 0.12 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MCR_0544 58f6c63b061342966b25e0671d7ea75d 457 SMART SM00228 116 187 7.2E-5 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MCR_0544 58f6c63b061342966b25e0671d7ea75d 457 SUPERFAMILY SSF50156 100 193 9.99E-16 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 MCR_0544 58f6c63b061342966b25e0671d7ea75d 457 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 6 455 2.1E-103 T 14-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 MCR_0544 58f6c63b061342966b25e0671d7ea75d 457 Pfam PF13180 PDZ domain 130 191 8.1E-8 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MCR_0544 58f6c63b061342966b25e0671d7ea75d 457 Gene3D G3DSA:2.30.42.10 127 222 4.4E-18 T 14-10-2018 MCR_0544 58f6c63b061342966b25e0671d7ea75d 457 Pfam PF02163 Peptidase family M50 10 441 2.3E-73 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 MCR_1419 8478e89bc99bda8a77f2194613cbbe52 365 Gene3D G3DSA:3.10.350.10 180 253 3.9E-14 T 14-10-2018 IPR036779 LysM domain superfamily MCR_1419 8478e89bc99bda8a77f2194613cbbe52 365 Pfam PF05036 Sporulation related domain 289 349 9.5E-10 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 MCR_1419 8478e89bc99bda8a77f2194613cbbe52 365 SMART SM00257 197 241 3.5E-10 T 14-10-2018 IPR018392 LysM domain MCR_1419 8478e89bc99bda8a77f2194613cbbe52 365 SUPERFAMILY SSF110997 288 351 5.23E-9 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MCR_1419 8478e89bc99bda8a77f2194613cbbe52 365 Pfam PF01476 LysM domain 198 241 6.2E-9 T 14-10-2018 IPR018392 LysM domain MCR_1419 8478e89bc99bda8a77f2194613cbbe52 365 SUPERFAMILY SSF54106 197 241 5.75E-8 T 14-10-2018 MCR_0760 d00de7792509b866235a2850d9d6fee5 189 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 85 98 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 MCR_0760 d00de7792509b866235a2850d9d6fee5 189 PIRSF PIRSF006443 10 179 2.1E-60 T 14-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 MCR_0760 d00de7792509b866235a2850d9d6fee5 189 Pfam PF00994 Probable molybdopterin binding domain 27 169 8.1E-31 T 14-10-2018 IPR001453 MoaB/Mog domain MCR_0760 d00de7792509b866235a2850d9d6fee5 189 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 21 181 7.8E-79 T 14-10-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 MCR_0760 d00de7792509b866235a2850d9d6fee5 189 Gene3D G3DSA:3.40.980.10 14 185 4.0E-49 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily MCR_0760 d00de7792509b866235a2850d9d6fee5 189 SUPERFAMILY SSF53218 19 183 4.19E-44 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily MCR_0760 d00de7792509b866235a2850d9d6fee5 189 SMART SM00852 27 171 3.4E-27 T 14-10-2018 IPR001453 MoaB/Mog domain MCR_0760 d00de7792509b866235a2850d9d6fee5 189 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 25 165 3.8E-32 T 14-10-2018 IPR001453 MoaB/Mog domain MCR_0436 76613c3ac2c109554801519ae952b0d4 210 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 19 210 28.361 T 14-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 MCR_0436 76613c3ac2c109554801519ae952b0d4 210 SUPERFAMILY SSF53335 34 209 3.07E-38 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0436 76613c3ac2c109554801519ae952b0d4 210 Gene3D G3DSA:3.40.50.150 34 210 9.9E-60 T 14-10-2018 MCR_0436 76613c3ac2c109554801519ae952b0d4 210 PIRSF PIRSF005461 3 210 9.4E-77 T 14-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 MCR_0436 76613c3ac2c109554801519ae952b0d4 210 Pfam PF01728 FtsJ-like methyltransferase 35 208 3.9E-55 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 MCR_0532 e77ac2ebd3ec10074046998784f6e996 139 Pfam PF01206 Sulfurtransferase TusA 64 113 3.9E-12 T 14-10-2018 IPR001455 TusA-like domain MCR_0532 e77ac2ebd3ec10074046998784f6e996 139 Gene3D G3DSA:3.30.110.40 58 136 7.7E-12 T 14-10-2018 IPR036868 TusA-like domain superfamily MCR_0532 e77ac2ebd3ec10074046998784f6e996 139 SUPERFAMILY SSF64307 62 115 3.14E-12 T 14-10-2018 IPR036868 TusA-like domain superfamily MCR_0652 dd5cab42cc28bda3901f251dfa504f93 114 Pfam PF11342 Protein of unknown function (DUF3144) 19 96 1.0E-25 T 14-10-2018 IPR021490 Protein of unknown function DUF3144 MCR_1583 be708114b85665fad78531e69aabb630 109 Pfam PF00276 Ribosomal protein L23 8 94 5.1E-27 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MCR_1583 be708114b85665fad78531e69aabb630 109 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 98 21.279 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MCR_1583 be708114b85665fad78531e69aabb630 109 Gene3D G3DSA:3.30.70.330 1 99 1.0E-30 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MCR_1583 be708114b85665fad78531e69aabb630 109 SUPERFAMILY SSF54189 3 92 3.24E-29 T 14-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1235 60f2ebc7185200f43497d6f4e7cc386c 171 Pfam PF03918 Cytochrome C biogenesis protein 9 154 7.8E-52 T 14-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family MCR_1235 60f2ebc7185200f43497d6f4e7cc386c 171 Gene3D G3DSA:1.10.8.640 20 107 6.7E-34 T 14-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily MCR_0690 96bdba32fa6ff092949ce4e62864752f 1074 Pfam PF00593 TonB dependent receptor 563 1072 3.0E-36 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MCR_0690 96bdba32fa6ff092949ce4e62864752f 1074 Pfam PF07715 TonB-dependent Receptor Plug Domain 78 184 8.1E-21 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain MCR_0690 96bdba32fa6ff092949ce4e62864752f 1074 Gene3D G3DSA:2.40.170.20 570 1074 4.5E-90 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MCR_0690 96bdba32fa6ff092949ce4e62864752f 1074 Gene3D G3DSA:2.170.130.10 70 196 9.3E-30 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MCR_0690 96bdba32fa6ff092949ce4e62864752f 1074 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 1057 1074 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site MCR_0690 96bdba32fa6ff092949ce4e62864752f 1074 TIGRFAM TIGR01776 TonB-tbp-lbp: TonB-dependent lactoferrin and transferrin receptors 1 1074 0.0 T 14-10-2018 IPR010948 TonB-dependent lactoferrin/transferrin receptor GO:0015091|GO:0015682|GO:0019867 MCR_0690 96bdba32fa6ff092949ce4e62864752f 1074 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 55 1074 6.7E-198 T 14-10-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0019867|GO:0022857|GO:0055085 MCR_0690 96bdba32fa6ff092949ce4e62864752f 1074 SUPERFAMILY SSF56935 55 1074 4.03E-73 T 14-10-2018 MCR_1653 fc9f05ea5cc0cae73c32cc4a1bbc49b5 149 PIRSF PIRSF006276 1 148 2.9E-17 T 14-10-2018 IPR006015 Universal stress protein A MCR_1653 fc9f05ea5cc0cae73c32cc4a1bbc49b5 149 Pfam PF00582 Universal stress protein family 1 144 1.3E-16 T 14-10-2018 IPR006016 UspA MCR_1653 fc9f05ea5cc0cae73c32cc4a1bbc49b5 149 Gene3D G3DSA:3.40.50.620 1 149 4.6E-19 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_1653 fc9f05ea5cc0cae73c32cc4a1bbc49b5 149 SUPERFAMILY SSF52402 1 144 3.27E-18 T 14-10-2018 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 Gene3D G3DSA:3.30.1360.10 17 224 3.8E-80 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 Gene3D G3DSA:2.170.120.12 52 174 3.8E-80 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 61 154 4.6E-21 T 14-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 Gene3D G3DSA:1.10.150.20 241 326 2.0E-36 T 14-10-2018 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 SMART SM00662 22 231 1.5E-89 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 323 5.0E-34 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 SUPERFAMILY SSF56553 52 175 4.19E-36 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 SUPERFAMILY SSF47789 248 321 5.1E-26 T 14-10-2018 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 23 313 7.3E-106 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 28 224 3.5E-23 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 SUPERFAMILY SSF55257 5 228 3.34E-30 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 4 314 34.745 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_1561 eda80fc47f17594bee75371c4faa321c 334 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 242 305 7.4E-25 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MCR_0016 69d0d5bf141e1840d8df8cd8ed61cd21 613 SUPERFAMILY SSF90123 33 520 3.01E-40 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MCR_0016 69d0d5bf141e1840d8df8cd8ed61cd21 613 Gene3D G3DSA:1.20.1560.10 20 336 2.6E-19 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MCR_0016 69d0d5bf141e1840d8df8cd8ed61cd21 613 ProSitePatterns PS00211 ABC transporters family signature. 507 521 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0016 69d0d5bf141e1840d8df8cd8ed61cd21 613 Pfam PF00005 ABC transporter 381 535 1.9E-38 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0016 69d0d5bf141e1840d8df8cd8ed61cd21 613 Pfam PF00664 ABC transporter transmembrane region 41 305 2.5E-12 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MCR_0016 69d0d5bf141e1840d8df8cd8ed61cd21 613 Gene3D G3DSA:3.40.50.300 360 606 3.1E-103 T 14-10-2018 MCR_0016 69d0d5bf141e1840d8df8cd8ed61cd21 613 SMART SM00382 390 581 1.5E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0016 69d0d5bf141e1840d8df8cd8ed61cd21 613 SUPERFAMILY SSF52540 350 605 7.43E-91 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1136 64b7a3f7df8d89617c2b22120faadfea 60 Pfam PF09791 Oxidoreductase-like protein, N-terminal 12 51 2.1E-7 T 14-10-2018 IPR019180 Oxidoreductase-like, N-terminal MCR_1454 8f67ec12f74d43462eea6fddcccb7590 177 Pfam PF00583 Acetyltransferase (GNAT) family 77 144 2.4E-11 T 14-10-2018 IPR000182 GNAT domain MCR_1454 8f67ec12f74d43462eea6fddcccb7590 177 Gene3D G3DSA:3.40.630.30 10 177 2.9E-29 T 14-10-2018 MCR_1454 8f67ec12f74d43462eea6fddcccb7590 177 SUPERFAMILY SSF55729 33 168 4.88E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MCR_0358 bf01460cb818b9422b72d3ed320c3afe 266 PIRSF PIRSF000370 46 266 2.3E-61 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MCR_0358 bf01460cb818b9422b72d3ed320c3afe 266 TIGRFAM TIGR04349 rSAM_QueE_gams: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 48 266 8.3E-92 T 14-10-2018 IPR027621 Putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE MCR_0358 bf01460cb818b9422b72d3ed320c3afe 266 SUPERFAMILY SSF102114 71 148 2.09E-12 T 14-10-2018 MCR_0358 bf01460cb818b9422b72d3ed320c3afe 266 Pfam PF13394 4Fe-4S single cluster domain 69 148 5.6E-9 T 14-10-2018 MCR_0358 bf01460cb818b9422b72d3ed320c3afe 266 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 48 263 35.969 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MCR_0358 bf01460cb818b9422b72d3ed320c3afe 266 Gene3D G3DSA:3.20.20.70 48 261 9.2E-35 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0358 bf01460cb818b9422b72d3ed320c3afe 266 Pfam PF04055 Radical SAM superfamily 72 147 1.2E-9 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MCR_0140 70c51fad77500057c4c196eb34e2ec89 343 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 36 103 2.1E-16 T 14-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MCR_0140 70c51fad77500057c4c196eb34e2ec89 343 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 24 342 45.864 T 14-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 MCR_0140 70c51fad77500057c4c196eb34e2ec89 343 Gene3D G3DSA:3.30.930.10 24 343 2.4E-119 T 14-10-2018 MCR_0140 70c51fad77500057c4c196eb34e2ec89 343 SUPERFAMILY SSF46589 31 115 6.28E-14 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MCR_0140 70c51fad77500057c4c196eb34e2ec89 343 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 55 342 9.8E-105 T 14-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MCR_0140 70c51fad77500057c4c196eb34e2ec89 343 Pfam PF01409 tRNA synthetases class II core domain (F) 108 342 6.5E-104 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 MCR_0140 70c51fad77500057c4c196eb34e2ec89 343 SUPERFAMILY SSF55681 108 342 1.65E-81 T 14-10-2018 MCR_1426 11459072fa598aeee1f5b3f76667d221 404 PIRSF PIRSF001413 3 404 1.7E-161 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MCR_1426 11459072fa598aeee1f5b3f76667d221 404 Gene3D G3DSA:3.40.50.1100 18 214 3.8E-183 T 14-10-2018 MCR_1426 11459072fa598aeee1f5b3f76667d221 404 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 10 399 51.151 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MCR_1426 11459072fa598aeee1f5b3f76667d221 404 Gene3D G3DSA:3.40.50.1100 62 392 3.8E-183 T 14-10-2018 MCR_1426 11459072fa598aeee1f5b3f76667d221 404 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 15 397 2.3E-189 T 14-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MCR_1426 11459072fa598aeee1f5b3f76667d221 404 SUPERFAMILY SSF53686 11 396 1.96E-145 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MCR_1426 11459072fa598aeee1f5b3f76667d221 404 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 89 103 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MCR_1426 11459072fa598aeee1f5b3f76667d221 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 386 8.9E-46 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MCR_1206 abda323505137ed32994c0fba0d18fa1 189 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 17 188 20.884 T 14-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 MCR_1206 abda323505137ed32994c0fba0d18fa1 189 Pfam PF03330 Lytic transglycolase 99 185 4.2E-20 T 14-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MCR_1206 abda323505137ed32994c0fba0d18fa1 189 Gene3D G3DSA:2.40.40.10 98 189 1.2E-32 T 14-10-2018 IPR036908 RlpA-like domain superfamily MCR_1206 abda323505137ed32994c0fba0d18fa1 189 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 101 188 2.8E-35 T 14-10-2018 IPR012997 Rare lipoprotein A MCR_1206 abda323505137ed32994c0fba0d18fa1 189 SUPERFAMILY SSF50685 100 178 4.19E-12 T 14-10-2018 IPR036908 RlpA-like domain superfamily MCR_0047 d2365cad1cf7c698b47999c8258ab311 265 Gene3D G3DSA:3.40.50.720 7 262 3.1E-91 T 14-10-2018 MCR_0047 d2365cad1cf7c698b47999c8258ab311 265 Gene3D G3DSA:3.30.360.10 126 232 3.1E-91 T 14-10-2018 MCR_0047 d2365cad1cf7c698b47999c8258ab311 265 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 149 166 - T 14-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_0047 d2365cad1cf7c698b47999c8258ab311 265 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 263 32.538 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_0047 d2365cad1cf7c698b47999c8258ab311 265 PIRSF PIRSF000161 2 265 4.6E-85 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_0047 d2365cad1cf7c698b47999c8258ab311 265 SUPERFAMILY SSF55347 127 234 3.92E-32 T 14-10-2018 MCR_0047 d2365cad1cf7c698b47999c8258ab311 265 SUPERFAMILY SSF51735 3 264 2.89E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0047 d2365cad1cf7c698b47999c8258ab311 265 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 127 262 9.0E-42 T 14-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_0047 d2365cad1cf7c698b47999c8258ab311 265 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 263 6.4E-82 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_0047 d2365cad1cf7c698b47999c8258ab311 265 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 124 9.8E-31 T 14-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MCR_0269 ab96e948fa36d5dcd10ee40c73de058a 140 Gene3D G3DSA:1.20.120.550 5 137 2.3E-16 T 14-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily MCR_0269 ab96e948fa36d5dcd10ee40c73de058a 140 Pfam PF01124 MAPEG family 14 135 1.5E-18 T 14-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein MCR_0269 ab96e948fa36d5dcd10ee40c73de058a 140 SUPERFAMILY SSF161084 16 134 7.85E-24 T 14-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily MCR_1843 2f5d9a3bf913f2a5839abf18e8180572 285 SMART SM00244 20 178 8.1E-54 T 14-10-2018 IPR001107 Band 7 domain MCR_1843 2f5d9a3bf913f2a5839abf18e8180572 285 Pfam PF01145 SPFH domain / Band 7 family 24 194 2.2E-34 T 14-10-2018 IPR001107 Band 7 domain MCR_1843 2f5d9a3bf913f2a5839abf18e8180572 285 Gene3D G3DSA:3.30.479.30 48 180 5.8E-38 T 14-10-2018 MCR_1843 2f5d9a3bf913f2a5839abf18e8180572 285 PRINTS PR00721 Stomatin signature 154 172 8.0E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MCR_1843 2f5d9a3bf913f2a5839abf18e8180572 285 PRINTS PR00721 Stomatin signature 110 127 8.0E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MCR_1843 2f5d9a3bf913f2a5839abf18e8180572 285 PRINTS PR00721 Stomatin signature 173 194 8.0E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MCR_1843 2f5d9a3bf913f2a5839abf18e8180572 285 PRINTS PR00721 Stomatin signature 130 153 8.0E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MCR_1843 2f5d9a3bf913f2a5839abf18e8180572 285 PRINTS PR00721 Stomatin signature 27 49 8.0E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MCR_1843 2f5d9a3bf913f2a5839abf18e8180572 285 PRINTS PR00721 Stomatin signature 75 96 8.0E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MCR_1843 2f5d9a3bf913f2a5839abf18e8180572 285 SUPERFAMILY SSF117892 51 185 1.2E-36 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily MCR_1731 b3641a2a571bbe9a7bb174dd6b62b71c 279 Gene3D G3DSA:3.40.50.300 28 276 4.2E-65 T 14-10-2018 MCR_1731 b3641a2a571bbe9a7bb174dd6b62b71c 279 ProSitePatterns PS00211 ABC transporters family signature. 176 190 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1731 b3641a2a571bbe9a7bb174dd6b62b71c 279 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 33 279 1.4E-119 T 14-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 MCR_1731 b3641a2a571bbe9a7bb174dd6b62b71c 279 SMART SM00382 57 251 4.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1731 b3641a2a571bbe9a7bb174dd6b62b71c 279 Pfam PF00005 ABC transporter 48 204 3.9E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1731 b3641a2a571bbe9a7bb174dd6b62b71c 279 SUPERFAMILY SSF52540 33 266 2.92E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1532 4040fd653a6265034e64249780e82361 410 SMART SM00525 221 241 4.4E-5 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MCR_1532 4040fd653a6265034e64249780e82361 410 SUPERFAMILY SSF55811 250 404 4.05E-9 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MCR_1532 4040fd653a6265034e64249780e82361 410 SMART SM00478 67 220 1.1E-34 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MCR_1532 4040fd653a6265034e64249780e82361 410 Pfam PF00633 Helix-hairpin-helix motif 132 157 8.6E-6 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MCR_1532 4040fd653a6265034e64249780e82361 410 Pfam PF14815 NUDIX domain 274 404 1.4E-11 T 14-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MCR_1532 4040fd653a6265034e64249780e82361 410 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 30 296 6.5E-93 T 14-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 MCR_1532 4040fd653a6265034e64249780e82361 410 Gene3D G3DSA:1.10.340.30 45 162 9.1E-76 T 14-10-2018 MCR_1532 4040fd653a6265034e64249780e82361 410 Gene3D G3DSA:1.10.1670.10 33 241 9.1E-76 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MCR_1532 4040fd653a6265034e64249780e82361 410 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 63 197 1.5E-15 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MCR_1532 4040fd653a6265034e64249780e82361 410 Gene3D G3DSA:3.90.79.10 253 409 4.1E-6 T 14-10-2018 MCR_1532 4040fd653a6265034e64249780e82361 410 SUPERFAMILY SSF48150 28 254 1.88E-62 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MCR_0977 2afb9cc2972b4767c5c7b69e203c35dd 229 Pfam PF01618 MotA/TolQ/ExbB proton channel family 90 203 1.0E-37 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MCR_0319 ce579cfb3a4102157dbfb151bbc4d63f 269 Pfam PF00899 ThiF family 28 267 8.4E-31 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MCR_0319 ce579cfb3a4102157dbfb151bbc4d63f 269 SUPERFAMILY SSF69572 18 268 4.45E-50 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MCR_0319 ce579cfb3a4102157dbfb151bbc4d63f 269 Gene3D G3DSA:3.40.50.720 9 269 1.5E-75 T 14-10-2018 MCR_0249 2598f8025c722664150d67ffe779784b 85 Gene3D G3DSA:1.10.260.40 1 78 3.7E-26 T 14-10-2018 MCR_0249 2598f8025c722664150d67ffe779784b 85 SUPERFAMILY SSF47413 6 69 2.43E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MCR_0300 d008aa1e04dc756b37e55d6c68774c29 295 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 277 1.6E-52 T 14-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 MCR_0300 d008aa1e04dc756b37e55d6c68774c29 295 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 1 275 35.152 T 14-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 MCR_0300 d008aa1e04dc756b37e55d6c68774c29 295 SUPERFAMILY SSF53335 8 282 6.44E-66 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0300 d008aa1e04dc756b37e55d6c68774c29 295 Gene3D G3DSA:3.40.50.150 1 295 1.4E-81 T 14-10-2018 MCR_0540 5aa1ed276fe2d44ec0f053efcced3313 184 Pfam PF01765 Ribosome recycling factor 21 182 1.6E-57 T 14-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 MCR_0540 5aa1ed276fe2d44ec0f053efcced3313 184 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 184 5.6E-65 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MCR_0540 5aa1ed276fe2d44ec0f053efcced3313 184 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 184 25.105 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MCR_0540 5aa1ed276fe2d44ec0f053efcced3313 184 Gene3D G3DSA:1.10.132.20 12 181 6.3E-62 T 14-10-2018 MCR_0540 5aa1ed276fe2d44ec0f053efcced3313 184 SUPERFAMILY SSF55194 1 184 2.75E-65 T 14-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 MCR_0540 5aa1ed276fe2d44ec0f053efcced3313 184 Gene3D G3DSA:3.30.1360.40 31 104 6.3E-62 T 14-10-2018 MCR_1621 b9ca713064b25e3f2ce6bffdb4350a15 720 Gene3D G3DSA:3.20.20.360 11 577 3.6E-254 T 14-10-2018 MCR_1621 b9ca713064b25e3f2ce6bffdb4350a15 720 Pfam PF01274 Malate synthase 19 692 5.6E-158 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MCR_1621 b9ca713064b25e3f2ce6bffdb4350a15 720 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 5 715 0.0 T 14-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MCR_1621 b9ca713064b25e3f2ce6bffdb4350a15 720 SUPERFAMILY SSF51645 4 717 3.79E-279 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MCR_1621 b9ca713064b25e3f2ce6bffdb4350a15 720 Hamap MF_00641 Malate synthase G [glcB]. 1 720 352.14 T 14-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MCR_1621 b9ca713064b25e3f2ce6bffdb4350a15 720 Gene3D G3DSA:2.170.170.11 133 260 3.6E-254 T 14-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MCR_1621 b9ca713064b25e3f2ce6bffdb4350a15 720 Gene3D G3DSA:1.20.1220.12 578 720 7.2E-69 T 14-10-2018 MCR_1433 2ddfac5edd13177bdfdb3a1c257d410a 184 PRINTS PR00607 Class IE cytochrome C signature 117 128 8.5E-9 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MCR_1433 2ddfac5edd13177bdfdb3a1c257d410a 184 PRINTS PR00607 Class IE cytochrome C signature 169 180 8.5E-9 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MCR_1433 2ddfac5edd13177bdfdb3a1c257d410a 184 PRINTS PR00607 Class IE cytochrome C signature 155 167 8.5E-9 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MCR_1433 2ddfac5edd13177bdfdb3a1c257d410a 184 PRINTS PR00607 Class IE cytochrome C signature 128 138 8.5E-9 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MCR_1433 2ddfac5edd13177bdfdb3a1c257d410a 184 Gene3D G3DSA:1.10.760.10 100 184 2.3E-28 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1433 2ddfac5edd13177bdfdb3a1c257d410a 184 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 106 179 3.0E-18 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1433 2ddfac5edd13177bdfdb3a1c257d410a 184 SUPERFAMILY SSF46626 4 183 9.18E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_0217 2fbd63eacae65b8e053817d30c83d29e 871 Pfam PF01298 C-lobe and N-lobe beta barrels of Tf-binding protein B 653 869 1.2E-32 T 14-10-2018 IPR001677 Transferrin-binding protein, C-lobe/N-lobe beta barrel domain MCR_0217 2fbd63eacae65b8e053817d30c83d29e 871 Pfam PF01298 C-lobe and N-lobe beta barrels of Tf-binding protein B 270 461 4.0E-32 T 14-10-2018 IPR001677 Transferrin-binding protein, C-lobe/N-lobe beta barrel domain MCR_0217 2fbd63eacae65b8e053817d30c83d29e 871 SUPERFAMILY SSF56925 247 461 1.1E-25 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MCR_0217 2fbd63eacae65b8e053817d30c83d29e 871 SUPERFAMILY SSF56925 611 869 6.28E-23 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MCR_0217 2fbd63eacae65b8e053817d30c83d29e 871 Gene3D G3DSA:2.40.160.90 267 492 6.8E-52 T 14-10-2018 MCR_1071 18bd3a77969fa55a0465cc8508cc3d8e 587 SUPERFAMILY SSF90123 27 351 4.84E-35 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MCR_1071 18bd3a77969fa55a0465cc8508cc3d8e 587 Pfam PF00005 ABC transporter 389 537 2.4E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1071 18bd3a77969fa55a0465cc8508cc3d8e 587 Gene3D G3DSA:1.20.1560.10 4 357 2.8E-29 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MCR_1071 18bd3a77969fa55a0465cc8508cc3d8e 587 SUPERFAMILY SSF52540 377 577 1.9E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1071 18bd3a77969fa55a0465cc8508cc3d8e 587 Pfam PF00664 ABC transporter transmembrane region 46 314 6.8E-19 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MCR_1071 18bd3a77969fa55a0465cc8508cc3d8e 587 SMART SM00382 395 584 1.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1071 18bd3a77969fa55a0465cc8508cc3d8e 587 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 35 578 7.0E-140 T 14-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 MCR_1071 18bd3a77969fa55a0465cc8508cc3d8e 587 Gene3D G3DSA:3.40.50.300 372 583 3.0E-50 T 14-10-2018 MCR_0056 164f77d5c96c6745ec09118d19c90fe9 108 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 77 104 5.8E-10 T 14-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 MCR_0056 164f77d5c96c6745ec09118d19c90fe9 108 SUPERFAMILY SSF57716 79 107 1.35E-6 T 14-10-2018 MCR_0056 164f77d5c96c6745ec09118d19c90fe9 108 SUPERFAMILY SSF109635 4 78 3.92E-6 T 14-10-2018 IPR037187 DksA, N-terminal domain superfamily MCR_0056 164f77d5c96c6745ec09118d19c90fe9 108 Gene3D G3DSA:1.20.120.910 1 108 1.4E-25 T 14-10-2018 MCR_0718 2a9bfa1b58c1f7851615e6d5ea8cc729 124 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 32 118 6.0E-20 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like MCR_0718 2a9bfa1b58c1f7851615e6d5ea8cc729 124 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 26 124 18.642 T 14-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 MCR_0715 1c5d20201397b480c8193405d8ec07d2 342 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 68 83 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0715 1c5d20201397b480c8193405d8ec07d2 342 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 223 236 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0715 1c5d20201397b480c8193405d8ec07d2 342 Pfam PF00146 NADH dehydrogenase 29 334 1.8E-117 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0715 1c5d20201397b480c8193405d8ec07d2 342 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 22 341 23.463 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_1699 401b09ca17b03afed5e6f869cd990c9f 249 SUPERFAMILY SSF63892 5 242 1.44E-89 T 14-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MCR_1699 401b09ca17b03afed5e6f869cd990c9f 249 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 246 109.715 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MCR_1699 401b09ca17b03afed5e6f869cd990c9f 249 Gene3D G3DSA:3.20.20.70 2 248 1.1E-96 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1699 401b09ca17b03afed5e6f869cd990c9f 249 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 239 8.6E-96 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MCR_1699 401b09ca17b03afed5e6f869cd990c9f 249 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 239 3.5E-87 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MCR_0058 9e608d42617cb012f3c17e926f838790 403 Gene3D G3DSA:1.10.3860.10 3 399 7.1E-67 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MCR_0058 9e608d42617cb012f3c17e926f838790 403 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 1 403 35.153 T 14-10-2018 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 MCR_0058 9e608d42617cb012f3c17e926f838790 403 Pfam PF00375 Sodium:dicarboxylate symporter family 13 394 5.7E-62 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MCR_0058 9e608d42617cb012f3c17e926f838790 403 SUPERFAMILY SSF118215 13 396 5.49E-88 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MCR_0058 9e608d42617cb012f3c17e926f838790 403 PRINTS PR00173 Glutamate-aspartate symporter signature 39 64 2.9E-18 T 14-10-2018 MCR_0058 9e608d42617cb012f3c17e926f838790 403 PRINTS PR00173 Glutamate-aspartate symporter signature 348 368 2.9E-18 T 14-10-2018 MCR_0058 9e608d42617cb012f3c17e926f838790 403 PRINTS PR00173 Glutamate-aspartate symporter signature 286 312 2.9E-18 T 14-10-2018 MCR_0058 9e608d42617cb012f3c17e926f838790 403 PRINTS PR00173 Glutamate-aspartate symporter signature 219 238 2.9E-18 T 14-10-2018 MCR_0058 9e608d42617cb012f3c17e926f838790 403 PRINTS PR00173 Glutamate-aspartate symporter signature 321 340 2.9E-18 T 14-10-2018 MCR_0058 9e608d42617cb012f3c17e926f838790 403 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 2.9E-18 T 14-10-2018 MCR_0058 9e608d42617cb012f3c17e926f838790 403 PRINTS PR00173 Glutamate-aspartate symporter signature 184 203 2.9E-18 T 14-10-2018 MCR_0845 144385ac35a15300bf62af6f9e1c0688 110 Pfam PF02575 YbaB/EbfC DNA-binding family 7 99 2.7E-28 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MCR_0845 144385ac35a15300bf62af6f9e1c0688 110 Gene3D G3DSA:3.30.1310.10 1 109 8.8E-34 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily MCR_0845 144385ac35a15300bf62af6f9e1c0688 110 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 105 6.1E-24 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MCR_0845 144385ac35a15300bf62af6f9e1c0688 110 PIRSF PIRSF004555 1 109 1.0E-30 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MCR_0845 144385ac35a15300bf62af6f9e1c0688 110 SUPERFAMILY SSF82607 7 103 6.67E-29 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily MCR_0845 144385ac35a15300bf62af6f9e1c0688 110 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 1 98 20.016 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MCR_0430 31d919329fde7765c4da69bef54e5352 191 SUPERFAMILY SSF50249 70 130 3.3E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0430 31d919329fde7765c4da69bef54e5352 191 PIRSF PIRSF005901 2 190 5.4E-64 T 14-10-2018 IPR020599 Translation elongation factor P/YeiP MCR_0430 31d919329fde7765c4da69bef54e5352 191 SMART SM00841 133 188 5.8E-31 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MCR_0430 31d919329fde7765c4da69bef54e5352 191 TIGRFAM TIGR00038 efp: translation elongation factor P 5 189 1.8E-75 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MCR_0430 31d919329fde7765c4da69bef54e5352 191 Gene3D G3DSA:2.40.50.140 66 131 2.4E-28 T 14-10-2018 MCR_0430 31d919329fde7765c4da69bef54e5352 191 SUPERFAMILY SSF50104 3 63 3.86E-21 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily MCR_0430 31d919329fde7765c4da69bef54e5352 191 Gene3D G3DSA:2.40.50.140 132 189 2.8E-26 T 14-10-2018 MCR_0430 31d919329fde7765c4da69bef54e5352 191 Hamap MF_00141 Elongation factor P [efp]. 3 189 48.393 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MCR_0430 31d919329fde7765c4da69bef54e5352 191 Pfam PF09285 Elongation factor P, C-terminal 133 188 1.3E-24 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MCR_0430 31d919329fde7765c4da69bef54e5352 191 Gene3D G3DSA:2.30.30.30 1 65 4.4E-28 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 MCR_0430 31d919329fde7765c4da69bef54e5352 191 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 62 6.2E-27 T 14-10-2018 IPR013185 Translation elongation factor, KOW-like MCR_0430 31d919329fde7765c4da69bef54e5352 191 SMART SM01185 69 125 6.1E-24 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MCR_0430 31d919329fde7765c4da69bef54e5352 191 SUPERFAMILY SSF50249 132 189 5.25E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0430 31d919329fde7765c4da69bef54e5352 191 Pfam PF01132 Elongation factor P (EF-P) OB domain 71 125 2.2E-21 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MCR_0233 466d6ece240760991343b12d4dd3126e 264 SUPERFAMILY SSF51735 107 261 6.23E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0233 466d6ece240760991343b12d4dd3126e 264 Gene3D G3DSA:3.40.50.10860 5 254 1.3E-69 T 14-10-2018 MCR_0233 466d6ece240760991343b12d4dd3126e 264 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 5 262 3.7E-70 T 14-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MCR_0233 466d6ece240760991343b12d4dd3126e 264 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 121 197 3.1E-13 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MCR_0233 466d6ece240760991343b12d4dd3126e 264 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 263 27.295 T 14-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MCR_0233 466d6ece240760991343b12d4dd3126e 264 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 94 7.5E-20 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MCR_0233 466d6ece240760991343b12d4dd3126e 264 SUPERFAMILY SSF53223 2 106 3.17E-24 T 14-10-2018 MCR_0233 466d6ece240760991343b12d4dd3126e 264 Gene3D G3DSA:3.40.50.720 120 235 1.3E-69 T 14-10-2018 MCR_0348 d1b7758f9ef21a984f84aff9c075e867 132 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 9 129 1.2E-48 T 14-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 MCR_0348 d1b7758f9ef21a984f84aff9c075e867 132 SUPERFAMILY SSF55298 7 131 3.3E-44 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MCR_0348 d1b7758f9ef21a984f84aff9c075e867 132 Pfam PF01042 Endoribonuclease L-PSP 15 129 9.7E-38 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MCR_0348 d1b7758f9ef21a984f84aff9c075e867 132 Gene3D G3DSA:3.30.1330.40 6 132 6.4E-49 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MCR_0348 d1b7758f9ef21a984f84aff9c075e867 132 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 107 125 - T 14-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 MCR_1587 adc95bb0483d587d10d601d58353f845 542 Pfam PF10150 Ribonuclease E/G family 167 445 5.6E-97 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MCR_1587 adc95bb0483d587d10d601d58353f845 542 SUPERFAMILY SSF50249 39 171 2.13E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_1587 adc95bb0483d587d10d601d58353f845 542 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 14 478 4.4E-147 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MCR_1587 adc95bb0483d587d10d601d58353f845 542 SMART SM00316 37 165 2.3E-6 T 14-10-2018 IPR022967 RNA-binding domain, S1 MCR_0609 00ddfe83baa436ffa7fb544af2dc0fe3 168 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 51 69 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site MCR_0609 00ddfe83baa436ffa7fb544af2dc0fe3 168 Gene3D G3DSA:1.10.10.10 1 146 3.3E-49 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0609 00ddfe83baa436ffa7fb544af2dc0fe3 168 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 132 1.3E-43 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type MCR_0609 00ddfe83baa436ffa7fb544af2dc0fe3 168 SUPERFAMILY SSF46785 2 134 9.97E-36 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0609 00ddfe83baa436ffa7fb544af2dc0fe3 168 Pfam PF02082 Transcriptional regulator 1 85 4.2E-26 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type MCR_1311 09451b60d58cb6dcacd0603adb11dab6 818 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 158 1.5E-12 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain MCR_1311 09451b60d58cb6dcacd0603adb11dab6 818 Gene3D G3DSA:2.170.130.10 51 168 1.4E-23 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MCR_1311 09451b60d58cb6dcacd0603adb11dab6 818 SUPERFAMILY SSF56935 60 818 8.11E-80 T 14-10-2018 MCR_1311 09451b60d58cb6dcacd0603adb11dab6 818 Pfam PF00593 TonB dependent receptor 343 817 1.9E-38 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MCR_1339 f4af8805d681fe48a9a41dbe1de60b22 271 Gene3D G3DSA:3.40.50.150 78 269 6.3E-51 T 14-10-2018 MCR_1339 f4af8805d681fe48a9a41dbe1de60b22 271 SUPERFAMILY SSF53335 78 261 6.44E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1339 f4af8805d681fe48a9a41dbe1de60b22 271 Pfam PF04445 Putative SAM-dependent methyltransferase 72 260 4.9E-37 T 14-10-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 MCR_1325 4fe5cc6e8402b41595baedbbf366b400 127 SUPERFAMILY SSF55718 1 108 4.0E-10 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily MCR_1325 4fe5cc6e8402b41595baedbbf366b400 127 Pfam PF02036 SCP-2 sterol transfer family 58 107 2.1E-4 T 14-10-2018 IPR003033 SCP2 sterol-binding domain MCR_1325 4fe5cc6e8402b41595baedbbf366b400 127 Gene3D G3DSA:3.30.1050.10 1 121 1.4E-11 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily MCR_0445 ba09431d5886a788254c4f860be21bd0 276 Pfam PF00756 Putative esterase 21 268 2.5E-59 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MCR_0445 ba09431d5886a788254c4f860be21bd0 276 Gene3D G3DSA:3.40.50.1820 1 276 6.2E-97 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0445 ba09431d5886a788254c4f860be21bd0 276 SUPERFAMILY SSF53474 1 275 1.74E-87 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0445 ba09431d5886a788254c4f860be21bd0 276 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 2 274 6.3E-120 T 14-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 MCR_1539 6249a1877d9be7ce251ea1ae493ffbb8 464 Pfam PF01554 MatE 26 186 1.4E-28 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MCR_1539 6249a1877d9be7ce251ea1ae493ffbb8 464 Pfam PF01554 MatE 253 416 1.2E-28 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MCR_1539 6249a1877d9be7ce251ea1ae493ffbb8 464 PIRSF PIRSF006603 10 463 1.7E-60 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MCR_1539 6249a1877d9be7ce251ea1ae493ffbb8 464 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 430 2.0E-80 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MCR_0721 8a3b0095984a253cea249e5f93a6c490 492 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 10 483 3.0E-112 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 MCR_0721 8a3b0095984a253cea249e5f93a6c490 492 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 7 483 16.664 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 MCR_0721 8a3b0095984a253cea249e5f93a6c490 492 Pfam PF00361 Proton-conducting membrane transporter 126 428 2.6E-65 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_1774 53c05119725850e7aba97263208f5561 494 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 12 490 31.601 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MCR_1774 53c05119725850e7aba97263208f5561 494 Pfam PF08245 Mur ligase middle domain 115 333 8.7E-41 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MCR_1774 53c05119725850e7aba97263208f5561 494 Gene3D G3DSA:3.40.1390.10 1 88 8.3E-30 T 14-10-2018 MCR_1774 53c05119725850e7aba97263208f5561 494 SUPERFAMILY SSF63418 8 104 1.15E-22 T 14-10-2018 IPR035911 MurE/MurF, N-terminal MCR_1774 53c05119725850e7aba97263208f5561 494 SUPERFAMILY SSF53244 355 488 1.14E-32 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_1774 53c05119725850e7aba97263208f5561 494 Pfam PF02875 Mur ligase family, glutamate ligase domain 355 433 6.0E-10 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MCR_1774 53c05119725850e7aba97263208f5561 494 Gene3D G3DSA:3.40.1190.10 89 351 5.7E-70 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_1774 53c05119725850e7aba97263208f5561 494 SUPERFAMILY SSF53623 108 351 5.61E-49 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_1774 53c05119725850e7aba97263208f5561 494 Gene3D G3DSA:3.90.190.20 354 492 1.9E-36 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_1774 53c05119725850e7aba97263208f5561 494 Pfam PF01225 Mur ligase family, catalytic domain 35 79 4.9E-10 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 Pfam PF07724 AAA domain (Cdc48 subfamily) 493 654 1.2E-46 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 Gene3D G3DSA:1.10.8.60 351 445 1.8E-29 T 14-10-2018 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 662 736 4.6E-21 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 Gene3D G3DSA:1.10.1780.10 1 138 1.0E-23 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 Gene3D G3DSA:3.40.50.300 161 350 8.1E-62 T 14-10-2018 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 206 303 3.2E-11 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 SUPERFAMILY SSF81923 1 136 2.04E-29 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 15 62 1.9E-11 T 14-10-2018 IPR004176 Clp, N-terminal MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 Gene3D G3DSA:1.10.8.60 660 762 5.5E-24 T 14-10-2018 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 Gene3D G3DSA:3.40.50.300 446 658 1.2E-78 T 14-10-2018 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 SUPERFAMILY SSF52540 163 415 1.3E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 540 558 7.0E-36 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 569 587 7.0E-36 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 602 616 7.0E-36 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 498 516 7.0E-36 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 525 543 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 SMART SM01086 660 752 2.4E-25 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 SMART SM00382 201 345 8.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 SMART SM00382 494 630 1.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1045 892a3594ad9c9801fc1ad9ef91372269 766 SUPERFAMILY SSF52540 444 735 7.25E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0167 c5643f1c1c699541eff9673f3c75fc4c 121 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 11 107 3.1E-34 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MCR_0167 c5643f1c1c699541eff9673f3c75fc4c 121 Pfam PF02410 Ribosomal silencing factor during starvation 13 107 2.3E-24 T 14-10-2018 MCR_0167 c5643f1c1c699541eff9673f3c75fc4c 121 SUPERFAMILY SSF81301 6 111 1.14E-33 T 14-10-2018 MCR_0167 c5643f1c1c699541eff9673f3c75fc4c 121 Gene3D G3DSA:3.30.460.10 5 118 8.9E-34 T 14-10-2018 MCR_0167 c5643f1c1c699541eff9673f3c75fc4c 121 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 6 108 22.801 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MCR_1111 ed4787d0d138a97a2a1012eda884d13e 346 SUPERFAMILY SSF56112 18 301 2.41E-38 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MCR_1111 ed4787d0d138a97a2a1012eda884d13e 346 Pfam PF01636 Phosphotransferase enzyme family 23 246 8.5E-25 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase MCR_1111 ed4787d0d138a97a2a1012eda884d13e 346 Gene3D G3DSA:3.90.1200.10 99 326 5.2E-67 T 14-10-2018 MCR_1111 ed4787d0d138a97a2a1012eda884d13e 346 Gene3D G3DSA:3.30.200.20 2 98 8.4E-18 T 14-10-2018 MCR_0571 9ec3d5f94d46594b29b06f69d3ba0c3f 305 Gene3D G3DSA:3.40.190.10 91 291 7.3E-55 T 14-10-2018 MCR_0571 9ec3d5f94d46594b29b06f69d3ba0c3f 305 Gene3D G3DSA:3.40.190.10 171 267 7.3E-55 T 14-10-2018 MCR_0571 9ec3d5f94d46594b29b06f69d3ba0c3f 305 Gene3D G3DSA:1.10.10.10 1 87 2.0E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0571 9ec3d5f94d46594b29b06f69d3ba0c3f 305 SUPERFAMILY SSF53850 91 294 3.08E-39 T 14-10-2018 MCR_0571 9ec3d5f94d46594b29b06f69d3ba0c3f 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 3.4E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_0571 9ec3d5f94d46594b29b06f69d3ba0c3f 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_0571 9ec3d5f94d46594b29b06f69d3ba0c3f 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_0571 9ec3d5f94d46594b29b06f69d3ba0c3f 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MCR_0571 9ec3d5f94d46594b29b06f69d3ba0c3f 305 Pfam PF03466 LysR substrate binding domain 95 295 1.8E-28 T 14-10-2018 IPR005119 LysR, substrate-binding MCR_0571 9ec3d5f94d46594b29b06f69d3ba0c3f 305 SUPERFAMILY SSF46785 5 85 6.53E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0485 509c271a2bdff79b27b788ad6247de74 278 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 5 272 1.5E-83 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MCR_0485 509c271a2bdff79b27b788ad6247de74 278 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 82 93 - T 14-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 MCR_0485 509c271a2bdff79b27b788ad6247de74 278 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 204 3.2E-27 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MCR_0485 509c271a2bdff79b27b788ad6247de74 278 Gene3D G3DSA:3.40.1010.10 1 110 4.5E-45 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MCR_0485 509c271a2bdff79b27b788ad6247de74 278 SUPERFAMILY SSF53790 3 223 2.09E-79 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MCR_0485 509c271a2bdff79b27b788ad6247de74 278 Gene3D G3DSA:3.30.950.10 112 230 8.8E-41 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MCR_0485 509c271a2bdff79b27b788ad6247de74 278 PIRSF PIRSF005917 1 277 1.0E-97 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MCR_0485 509c271a2bdff79b27b788ad6247de74 278 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 4 225 35.805 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MCR_1113 cc931440575ba4dabd7d87b15c9384af 926 Pfam PF03968 OstA-like protein 197 334 3.9E-5 T 14-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal MCR_1113 cc931440575ba4dabd7d87b15c9384af 926 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 16 900 17.635 T 14-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 MCR_1113 cc931440575ba4dabd7d87b15c9384af 926 Pfam PF04453 Organic solvent tolerance protein 447 837 1.3E-54 T 14-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 MCR_1547 a6a6aecc4371e05b1266fd025a8ce714 171 Pfam PF13710 ACT domain 18 78 2.0E-15 T 14-10-2018 MCR_1547 a6a6aecc4371e05b1266fd025a8ce714 171 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 6 81 2.0E-25 T 14-10-2018 MCR_1547 a6a6aecc4371e05b1266fd025a8ce714 171 Gene3D G3DSA:3.30.70.260 5 80 2.2E-30 T 14-10-2018 MCR_1547 a6a6aecc4371e05b1266fd025a8ce714 171 SUPERFAMILY SSF55021 7 80 9.89E-21 T 14-10-2018 MCR_1547 a6a6aecc4371e05b1266fd025a8ce714 171 Gene3D G3DSA:3.30.70.1150 91 171 1.5E-28 T 14-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal MCR_1547 a6a6aecc4371e05b1266fd025a8ce714 171 SUPERFAMILY SSF55021 87 169 4.58E-27 T 14-10-2018 MCR_1547 a6a6aecc4371e05b1266fd025a8ce714 171 Pfam PF10369 Small subunit of acetolactate synthase 92 165 6.2E-26 T 14-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MCR_1547 a6a6aecc4371e05b1266fd025a8ce714 171 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 6 166 1.2E-55 T 14-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MCR_0633 445a1c5793b993cca5e02d9aedf04fc6 546 Pfam PF03109 ABC1 family 113 230 1.5E-33 T 14-10-2018 IPR004147 UbiB domain MCR_0633 445a1c5793b993cca5e02d9aedf04fc6 546 SUPERFAMILY SSF56112 91 438 1.11E-21 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MCR_1585 b91dd9b99f046ab7b9720b570d5170b2 212 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 210 38.089 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1585 b91dd9b99f046ab7b9720b570d5170b2 212 Gene3D G3DSA:2.40.30.10 133 212 8.9E-16 T 14-10-2018 MCR_1585 b91dd9b99f046ab7b9720b570d5170b2 212 Pfam PF00297 Ribosomal protein L3 99 185 1.1E-13 T 14-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1585 b91dd9b99f046ab7b9720b570d5170b2 212 SUPERFAMILY SSF50447 2 211 2.65E-77 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MCR_1585 b91dd9b99f046ab7b9720b570d5170b2 212 ProSitePatterns PS00474 Ribosomal protein L3 signature. 104 127 - T 14-10-2018 IPR019926 Ribosomal protein L3, conserved site MCR_1585 b91dd9b99f046ab7b9720b570d5170b2 212 Gene3D G3DSA:2.40.50.620 34 92 5.3E-13 T 14-10-2018 MCR_1585 b91dd9b99f046ab7b9720b570d5170b2 212 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 207 2.6E-84 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0681 cf68bfa7d111209baddd058f677caa79 303 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 140 168 - T 14-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MCR_0681 cf68bfa7d111209baddd058f677caa79 303 Gene3D G3DSA:1.10.530.10 71 244 3.8E-52 T 14-10-2018 MCR_0681 cf68bfa7d111209baddd058f677caa79 303 SUPERFAMILY SSF53955 97 239 1.75E-46 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MCR_0681 cf68bfa7d111209baddd058f677caa79 303 Pfam PF01464 Transglycosylase SLT domain 122 229 2.4E-29 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 MCR_0988 07ea13a384206cac09e5fc4e528025a2 134 SUPERFAMILY SSF143100 2 67 5.1E-8 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like MCR_0988 07ea13a384206cac09e5fc4e528025a2 134 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 129 4.2E-37 T 14-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system MCR_0988 07ea13a384206cac09e5fc4e528025a2 134 Gene3D G3DSA:3.30.160.250 1 85 1.5E-14 T 14-10-2018 MCR_0600 e76c1e8b06b700e8f6b77998bf42bb55 87 SUPERFAMILY SSF52833 1 82 4.1E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0600 e76c1e8b06b700e8f6b77998bf42bb55 87 Gene3D G3DSA:3.40.30.10 1 82 1.1E-24 T 14-10-2018 MCR_0600 e76c1e8b06b700e8f6b77998bf42bb55 87 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 1 81 1.2E-36 T 14-10-2018 IPR004480 Monothiol glutaredoxin-related MCR_0600 e76c1e8b06b700e8f6b77998bf42bb55 87 PIRSF PIRSF005894 1 87 2.6E-39 T 14-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 MCR_0600 e76c1e8b06b700e8f6b77998bf42bb55 87 Pfam PF00462 Glutaredoxin 7 61 1.0E-15 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MCR_1281 56a93f15349c6fed03adf5c48982f811 126 Pfam PF01597 Glycine cleavage H-protein 8 124 4.1E-48 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate MCR_1281 56a93f15349c6fed03adf5c48982f811 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 125 7.4E-52 T 14-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MCR_1281 56a93f15349c6fed03adf5c48982f811 126 Gene3D G3DSA:2.40.50.100 2 126 1.6E-49 T 14-10-2018 MCR_1281 56a93f15349c6fed03adf5c48982f811 126 SUPERFAMILY SSF51230 3 124 3.53E-47 T 14-10-2018 IPR011053 Single hybrid motif MCR_1281 56a93f15349c6fed03adf5c48982f811 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 125 40.844 T 14-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MCR_1281 56a93f15349c6fed03adf5c48982f811 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MCR_1392 570e494c198273de8624c32a2fcd0a0b 409 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 8 380 1.7E-151 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MCR_1392 570e494c198273de8624c32a2fcd0a0b 409 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 5 394 23.182 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MCR_1392 570e494c198273de8624c32a2fcd0a0b 409 Pfam PF06965 Na+/H+ antiporter 1 7 380 1.1E-150 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MCR_1392 570e494c198273de8624c32a2fcd0a0b 409 Gene3D G3DSA:1.20.1530.10 2 387 1.8E-149 T 14-10-2018 IPR023171 Na/H antiporter domain superfamily MCR_1712 2992d059956614b2e9accae9e366d78a 154 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 1.9E-55 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 MCR_1712 2992d059956614b2e9accae9e366d78a 154 SUPERFAMILY SSF74982 3 133 4.84E-52 T 14-10-2018 IPR023620 Small protein B MCR_1712 2992d059956614b2e9accae9e366d78a 154 Gene3D G3DSA:2.40.280.10 2 130 4.9E-49 T 14-10-2018 IPR023620 Small protein B MCR_1712 2992d059956614b2e9accae9e366d78a 154 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 133 5.0E-58 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 MCR_1712 2992d059956614b2e9accae9e366d78a 154 Pfam PF01668 SmpB protein 9 151 7.7E-59 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 MCR_1712 2992d059956614b2e9accae9e366d78a 154 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 14-10-2018 IPR020081 SsrA-binding protein, conserved site MCR_1712 2992d059956614b2e9accae9e366d78a 154 Hamap MF_00023 SsrA-binding protein [smpB]. 1 154 71.799 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 MCR_0621 07fcc58a3c394af4aaf61d0a130375b9 310 SUPERFAMILY SSF53335 61 279 3.11E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0621 07fcc58a3c394af4aaf61d0a130375b9 310 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 306 29.435 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MCR_0621 07fcc58a3c394af4aaf61d0a130375b9 310 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 281 7.9E-77 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MCR_0621 07fcc58a3c394af4aaf61d0a130375b9 310 Gene3D G3DSA:3.40.50.150 105 292 1.4E-50 T 14-10-2018 MCR_0621 07fcc58a3c394af4aaf61d0a130375b9 310 PIRSF PIRSF000401 1 306 2.8E-71 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MCR_0621 07fcc58a3c394af4aaf61d0a130375b9 310 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 285 5.9E-78 T 14-10-2018 MCR_1059 5b6a90bfdde3321c53eea6cfe141d6a8 232 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 114 2.8E-5 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MCR_1059 5b6a90bfdde3321c53eea6cfe141d6a8 232 Gene3D G3DSA:3.40.50.720 1 224 1.3E-29 T 14-10-2018 MCR_1059 5b6a90bfdde3321c53eea6cfe141d6a8 232 SUPERFAMILY SSF51735 2 202 1.14E-18 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1558 d7f5b740eaaa4760df35f8a4cbcb9056 252 Pfam PF04315 Elongation factor P hydroxylase 88 239 2.8E-57 T 14-10-2018 IPR007411 Elongation factor P hydroxylase MCR_1740 e85e56f5384db30681764bb18993d510 106 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 105 5.6E-39 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MCR_1740 e85e56f5384db30681764bb18993d510 106 PIRSF PIRSF000077 1 106 7.0E-44 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MCR_1740 e85e56f5384db30681764bb18993d510 106 PRINTS PR00421 Thioredoxin family signature 30 39 1.9E-9 T 14-10-2018 MCR_1740 e85e56f5384db30681764bb18993d510 106 PRINTS PR00421 Thioredoxin family signature 22 30 1.9E-9 T 14-10-2018 MCR_1740 e85e56f5384db30681764bb18993d510 106 PRINTS PR00421 Thioredoxin family signature 70 81 1.9E-9 T 14-10-2018 MCR_1740 e85e56f5384db30681764bb18993d510 106 Gene3D G3DSA:3.40.30.10 1 106 5.1E-38 T 14-10-2018 MCR_1740 e85e56f5384db30681764bb18993d510 106 Pfam PF00085 Thioredoxin 3 105 8.8E-36 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 MCR_1740 e85e56f5384db30681764bb18993d510 106 SUPERFAMILY SSF52833 2 106 1.09E-41 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_1740 e85e56f5384db30681764bb18993d510 106 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MCR_0163 f107a3f7ade0e97b15aaa30c477fc82c 234 Pfam PF13500 AAA domain 13 208 3.6E-27 T 14-10-2018 MCR_0163 f107a3f7ade0e97b15aaa30c477fc82c 234 SUPERFAMILY SSF52540 10 217 1.5E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0163 f107a3f7ade0e97b15aaa30c477fc82c 234 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 15 187 8.4E-42 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MCR_0163 f107a3f7ade0e97b15aaa30c477fc82c 234 PIRSF PIRSF006755 10 228 5.8E-53 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MCR_0163 f107a3f7ade0e97b15aaa30c477fc82c 234 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 11 228 24.047 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MCR_0163 f107a3f7ade0e97b15aaa30c477fc82c 234 Gene3D G3DSA:3.40.50.300 10 219 1.4E-49 T 14-10-2018 MCR_0839 b1933ab87fbe93dbe538863838a4db6e 365 SUPERFAMILY SSF52540 123 299 7.96E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0839 b1933ab87fbe93dbe538863838a4db6e 365 Pfam PF02562 PhoH-like protein 124 327 9.2E-93 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 MCR_0839 b1933ab87fbe93dbe538863838a4db6e 365 Gene3D G3DSA:3.40.50.300 121 327 3.2E-72 T 14-10-2018 MCR_1442 917232452ba8d7d812cbab00ff21a4c4 634 SUPERFAMILY SSF53067 69 186 5.05E-8 T 14-10-2018 MCR_1442 917232452ba8d7d812cbab00ff21a4c4 634 Pfam PF11104 Type IV pilus assembly protein PilM; 29 203 1.4E-25 T 14-10-2018 IPR005883 Type IV pilus assembly protein PilM MCR_1442 917232452ba8d7d812cbab00ff21a4c4 634 Pfam PF05137 Fimbrial assembly protein (PilN) 534 604 7.1E-15 T 14-10-2018 IPR007813 Fimbrial assembly PilN MCR_1442 917232452ba8d7d812cbab00ff21a4c4 634 Gene3D G3DSA:3.30.1490.300 103 156 2.3E-11 T 14-10-2018 MCR_1314 f2d0267890e803dec8fc117d1c5e3ebc 842 Pfam PF03772 Competence protein 294 577 5.1E-47 T 14-10-2018 IPR004477 ComEC/Rec2-related protein MCR_1314 f2d0267890e803dec8fc117d1c5e3ebc 842 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 315 509 2.4E-21 T 14-10-2018 IPR004477 ComEC/Rec2-related protein MCR_0384 606488ccb99ce570e1199c45e0fd2180 118 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 1 69 2.0E-12 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0384 606488ccb99ce570e1199c45e0fd2180 118 SUPERFAMILY SSF51344 1 65 9.94E-18 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0384 606488ccb99ce570e1199c45e0fd2180 118 Gene3D G3DSA:1.20.5.440 70 112 1.2E-9 T 14-10-2018 MCR_0384 606488ccb99ce570e1199c45e0fd2180 118 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 1 110 12.028 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0384 606488ccb99ce570e1199c45e0fd2180 118 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 2 111 1.2E-32 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0384 606488ccb99ce570e1199c45e0fd2180 118 SUPERFAMILY SSF46604 68 115 1.99E-11 T 14-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0384 606488ccb99ce570e1199c45e0fd2180 118 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 1 63 6.1E-22 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0384 606488ccb99ce570e1199c45e0fd2180 118 Gene3D G3DSA:2.60.15.10 1 69 3.9E-22 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_1557 bdeabca49161467d0bcfb28e0fbb48b9 181 Pfam PF02620 Uncharacterized ACR, COG1399 68 177 1.0E-13 T 14-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD MCR_1330 98ab4f411d1bacdcf0f1a7f75bcaf7aa 448 Gene3D G3DSA:3.40.50.620 16 193 5.6E-116 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_1330 98ab4f411d1bacdcf0f1a7f75bcaf7aa 448 Gene3D G3DSA:3.90.1260.10 76 369 5.6E-116 T 14-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MCR_1330 98ab4f411d1bacdcf0f1a7f75bcaf7aa 448 Hamap MF_00581 Argininosuccinate synthase [argG]. 3 446 69.002 T 14-10-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MCR_1330 98ab4f411d1bacdcf0f1a7f75bcaf7aa 448 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 131 142 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MCR_1330 98ab4f411d1bacdcf0f1a7f75bcaf7aa 448 SUPERFAMILY SSF52402 6 187 1.41E-32 T 14-10-2018 MCR_1330 98ab4f411d1bacdcf0f1a7f75bcaf7aa 448 Gene3D G3DSA:1.10.287.400 379 443 2.7E-28 T 14-10-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MCR_1330 98ab4f411d1bacdcf0f1a7f75bcaf7aa 448 Pfam PF00764 Arginosuccinate synthase 18 396 8.1E-58 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MCR_1330 98ab4f411d1bacdcf0f1a7f75bcaf7aa 448 TIGRFAM TIGR00032 argG: argininosuccinate synthase 15 422 3.2E-159 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MCR_1330 98ab4f411d1bacdcf0f1a7f75bcaf7aa 448 SUPERFAMILY SSF69864 192 445 4.97E-76 T 14-10-2018 MCR_1330 98ab4f411d1bacdcf0f1a7f75bcaf7aa 448 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 19 27 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MCR_0804 ecbcdf55e1507aab9a4a1cef04781041 431 SUPERFAMILY SSF143865 105 363 5.75E-65 T 14-10-2018 MCR_0804 ecbcdf55e1507aab9a4a1cef04781041 431 Pfam PF01544 CorA-like Mg2+ transporter protein 135 427 1.1E-59 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MCR_0804 ecbcdf55e1507aab9a4a1cef04781041 431 SUPERFAMILY SSF144083 367 428 2.75E-17 T 14-10-2018 MCR_0804 ecbcdf55e1507aab9a4a1cef04781041 431 Gene3D G3DSA:1.20.58.340 238 353 6.6E-27 T 14-10-2018 MCR_0804 ecbcdf55e1507aab9a4a1cef04781041 431 Gene3D G3DSA:1.20.58.340 355 431 5.1E-21 T 14-10-2018 MCR_0804 ecbcdf55e1507aab9a4a1cef04781041 431 Gene3D G3DSA:3.30.460.20 76 237 6.6E-27 T 14-10-2018 MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 Pfam PF02926 THUMP domain 75 216 2.1E-5 T 14-10-2018 IPR004114 THUMP domain GO:0003723 MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 PIRSF PIRSF037618 44 805 8.5E-255 T 14-10-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 Gene3D G3DSA:3.30.2130.30 51 325 2.6E-88 T 14-10-2018 MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 49 804 26.675 T 14-10-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 Gene3D G3DSA:3.40.50.150 232 455 2.6E-88 T 14-10-2018 MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 Pfam PF01170 Putative RNA methylase family UPF0020 225 414 2.3E-28 T 14-10-2018 IPR000241 Putative RNA methylase domain MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 381 387 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 593 756 1.5E-22 T 14-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 SUPERFAMILY SSF53335 489 804 4.01E-58 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 Gene3D G3DSA:3.40.50.150 578 804 1.0E-63 T 14-10-2018 MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 SUPERFAMILY SSF53335 214 408 3.82E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 Gene3D G3DSA:3.30.750.80 486 577 7.6E-29 T 14-10-2018 MCR_1102 b4aafecf1ceae2d8c3bf39244c047390 932 SMART SM00981 125 217 1.0E-4 T 14-10-2018 IPR004114 THUMP domain GO:0003723 MCR_0746 cadb7a7fd462dc806444e9f203110754 1251 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 1.3E-15 T 14-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 MCR_0746 cadb7a7fd462dc806444e9f203110754 1251 SUPERFAMILY SSF53706 4 1070 0.0 T 14-10-2018 MCR_0746 cadb7a7fd462dc806444e9f203110754 1251 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 MCR_0746 cadb7a7fd462dc806444e9f203110754 1251 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 776 793 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MCR_0746 cadb7a7fd462dc806444e9f203110754 1251 Gene3D G3DSA:3.40.50.12440 44 1244 0.0 T 14-10-2018 MCR_0746 cadb7a7fd462dc806444e9f203110754 1251 SMART SM00926 43 105 6.1E-8 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0746 cadb7a7fd462dc806444e9f203110754 1251 SUPERFAMILY SSF50692 1082 1235 5.42E-47 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MCR_0746 cadb7a7fd462dc806444e9f203110754 1251 Pfam PF00384 Molybdopterin oxidoreductase 108 832 4.6E-162 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0746 cadb7a7fd462dc806444e9f203110754 1251 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1235 0.0 T 14-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 MCR_0746 cadb7a7fd462dc806444e9f203110754 1251 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1125 1152 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MCR_0746 cadb7a7fd462dc806444e9f203110754 1251 Pfam PF01568 Molydopterin dinucleotide binding domain 1088 1202 4.9E-22 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MCR_1639 2d9837c524fc24925a52d50a3f69ff55 301 SUPERFAMILY SSF56349 2 249 1.21E-40 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MCR_1639 2d9837c524fc24925a52d50a3f69ff55 301 Gene3D G3DSA:1.10.150.130 1 79 3.6E-6 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal MCR_1639 2d9837c524fc24925a52d50a3f69ff55 301 Gene3D G3DSA:1.10.443.10 84 253 5.7E-20 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MCR_1639 2d9837c524fc24925a52d50a3f69ff55 301 Pfam PF00589 Phage integrase family 86 241 3.2E-23 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MCR_0341 801080e05411271034ceb6a9fdcd1835 212 SUPERFAMILY SSF101327 10 169 1.83E-29 T 14-10-2018 IPR036255 YgfB-like superfamily MCR_0341 801080e05411271034ceb6a9fdcd1835 212 Gene3D G3DSA:1.20.120.740 3 179 2.6E-33 T 14-10-2018 MCR_0341 801080e05411271034ceb6a9fdcd1835 212 Pfam PF03695 Uncharacterised protein family (UPF0149) 22 168 5.7E-16 T 14-10-2018 IPR011978 Uncharacterised protein family UPF0149 MCR_0864 de8a88e649620fb6ffaf19d2f691d500 317 Pfam PF14237 Domain of unknown function (DUF4339) 4 46 2.1E-12 T 14-10-2018 IPR025640 Domain of unknown function DUF4339 Reactome: R-HSA-6798695 MCR_0864 de8a88e649620fb6ffaf19d2f691d500 317 Pfam PF06271 RDD family 140 300 5.1E-18 T 14-10-2018 IPR010432 RDD MCR_1246 3c3b11e5173942e914ddc622d406ba7e 222 Pfam PF07819 PGAP1-like protein 53 107 6.9E-6 T 14-10-2018 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 MCR_1246 3c3b11e5173942e914ddc622d406ba7e 222 SUPERFAMILY SSF53474 3 196 1.51E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0541 d90b001ed4afecfe6706ab17607a2ff4 248 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 12 239 1.7E-80 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MCR_0541 d90b001ed4afecfe6706ab17607a2ff4 248 SUPERFAMILY SSF64005 12 235 5.49E-79 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MCR_0541 d90b001ed4afecfe6706ab17607a2ff4 248 Gene3D G3DSA:3.40.1180.10 3 240 3.4E-86 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MCR_0541 d90b001ed4afecfe6706ab17607a2ff4 248 Pfam PF01255 Putative undecaprenyl diphosphate synthase 19 239 2.7E-72 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MCR_0541 d90b001ed4afecfe6706ab17607a2ff4 248 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 12 240 35.718 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MCR_0541 d90b001ed4afecfe6706ab17607a2ff4 248 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 185 202 - T 14-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 MCR_0994 6b7bd028fe01bb635e5290d4e6774a3c 391 Pfam PF06969 HemN C-terminal domain 318 380 3.2E-9 T 14-10-2018 IPR010723 HemN, C-terminal MCR_0994 6b7bd028fe01bb635e5290d4e6774a3c 391 Gene3D G3DSA:3.80.30.20 4 310 2.4E-92 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MCR_0994 6b7bd028fe01bb635e5290d4e6774a3c 391 Pfam PF04055 Radical SAM superfamily 17 181 6.6E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MCR_0994 6b7bd028fe01bb635e5290d4e6774a3c 391 SUPERFAMILY SSF102114 12 391 2.49E-99 T 14-10-2018 MCR_0994 6b7bd028fe01bb635e5290d4e6774a3c 391 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 13 357 1.3E-102 T 14-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 MCR_0994 6b7bd028fe01bb635e5290d4e6774a3c 391 SMART SM00729 12 229 4.5E-42 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MCR_1762 a1a8145647ca7be4a125710c5cca5db4 311 SUPERFAMILY SSF55120 11 246 2.18E-69 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1762 a1a8145647ca7be4a125710c5cca5db4 311 Gene3D G3DSA:3.30.2350.10 2 247 6.2E-78 T 14-10-2018 MCR_1762 a1a8145647ca7be4a125710c5cca5db4 311 Gene3D G3DSA:2.30.130.10 248 311 3.8E-5 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 MCR_1762 a1a8145647ca7be4a125710c5cca5db4 311 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 40 186 6.7E-54 T 14-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 MCR_1762 a1a8145647ca7be4a125710c5cca5db4 311 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 11 310 17.158 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1762 a1a8145647ca7be4a125710c5cca5db4 311 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 12 225 4.9E-66 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1762 a1a8145647ca7be4a125710c5cca5db4 311 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 248 310 5.4E-11 T 14-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1762 a1a8145647ca7be4a125710c5cca5db4 311 SUPERFAMILY SSF88697 247 310 1.94E-6 T 14-10-2018 IPR015947 PUA-like superfamily MCR_1807 a3a9c1745384ec61562eddc0d9329234 422 SMART SM00984 302 403 1.5E-4 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MCR_1807 a3a9c1745384ec61562eddc0d9329234 422 SUPERFAMILY SSF48179 187 283 7.99E-21 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MCR_1807 a3a9c1745384ec61562eddc0d9329234 422 Gene3D G3DSA:1.20.5.100 189 215 1.4E-7 T 14-10-2018 MCR_1807 a3a9c1745384ec61562eddc0d9329234 422 SUPERFAMILY SSF52413 287 409 2.09E-8 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 MCR_1807 a3a9c1745384ec61562eddc0d9329234 422 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 189 278 1.3E-21 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MCR_1807 a3a9c1745384ec61562eddc0d9329234 422 Gene3D G3DSA:3.40.50.720 217 421 1.4E-35 T 14-10-2018 MCR_0171 d53808ea389345547edad1ccde841c8f 383 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 382 1.1E-135 T 14-10-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain MCR_0171 d53808ea389345547edad1ccde841c8f 383 SUPERFAMILY SSF52440 168 275 3.16E-34 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MCR_0171 d53808ea389345547edad1ccde841c8f 383 Gene3D G3DSA:3.30.1490.330 259 336 3.7E-25 T 14-10-2018 MCR_0171 d53808ea389345547edad1ccde841c8f 383 SUPERFAMILY SSF56059 1 380 3.35E-69 T 14-10-2018 MCR_1750 d98840d4e6b4da96b2714bb6481bfbd4 253 Pfam PF04972 BON domain 42 111 1.6E-5 T 14-10-2018 IPR007055 BON domain MCR_1422 5e20ac5d876eeb09f7e948e90d30bd4e 442 PIRSF PIRSF001563 1 440 1.3E-89 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MCR_1422 5e20ac5d876eeb09f7e948e90d30bd4e 442 Gene3D G3DSA:3.40.1190.10 1 289 2.6E-82 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_1422 5e20ac5d876eeb09f7e948e90d30bd4e 442 Pfam PF08245 Mur ligase middle domain 55 230 6.2E-15 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MCR_1422 5e20ac5d876eeb09f7e948e90d30bd4e 442 SUPERFAMILY SSF53244 290 435 4.94E-20 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_1422 5e20ac5d876eeb09f7e948e90d30bd4e 442 Gene3D G3DSA:3.90.190.20 290 439 2.8E-22 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MCR_1422 5e20ac5d876eeb09f7e948e90d30bd4e 442 SUPERFAMILY SSF53623 3 287 1.14E-75 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MCR_1422 5e20ac5d876eeb09f7e948e90d30bd4e 442 TIGRFAM TIGR01499 folC: bifunctional protein FolC 47 434 8.7E-88 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MCR_0390 81341c7a7586f52c1c226f8e9b6b5491 250 PIRSF PIRSF000386 1 249 7.4E-86 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MCR_0390 81341c7a7586f52c1c226f8e9b6b5491 250 SUPERFAMILY SSF75217 3 248 7.19E-91 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MCR_0390 81341c7a7586f52c1c226f8e9b6b5491 250 Gene3D G3DSA:3.40.1280.10 1 173 2.6E-58 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MCR_0390 81341c7a7586f52c1c226f8e9b6b5491 250 Gene3D G3DSA:1.10.1270.20 174 250 2.1E-28 T 14-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MCR_0390 81341c7a7586f52c1c226f8e9b6b5491 250 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 250 95.842 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MCR_0390 81341c7a7586f52c1c226f8e9b6b5491 250 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 229 2.9E-52 T 14-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MCR_0390 81341c7a7586f52c1c226f8e9b6b5491 250 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 2 241 2.7E-86 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MCR_0504 2818e63b1ede1632e45e734cf4d09e14 439 Pfam PF00860 Permease family 28 397 1.4E-93 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MCR_0504 2818e63b1ede1632e45e734cf4d09e14 439 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 26 421 1.8E-104 T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MCR_1467 5ccacb21f9f2b31265c71a0e01879bbb 344 PIRSF PIRSF005632 1 343 5.0E-191 T 14-10-2018 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit MCR_1467 5ccacb21f9f2b31265c71a0e01879bbb 344 SUPERFAMILY SSF51726 8 343 1.06E-70 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MCR_1467 5ccacb21f9f2b31265c71a0e01879bbb 344 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 6 332 2.1E-37 T 14-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MCR_1467 5ccacb21f9f2b31265c71a0e01879bbb 344 Gene3D G3DSA:3.20.20.210 1 343 4.9E-131 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MCR_1810 e2a15000e3d3851784317e04395c6bde 859 SUPERFAMILY SSF69593 278 531 4.05E-25 T 14-10-2018 MCR_1810 e2a15000e3d3851784317e04395c6bde 859 Pfam PF01553 Acyltransferase 317 450 4.9E-22 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MCR_1810 e2a15000e3d3851784317e04395c6bde 859 SMART SM00563 326 453 1.9E-29 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MCR_1810 e2a15000e3d3851784317e04395c6bde 859 PIRSF PIRSF500064 43 842 6.4E-221 T 14-10-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109|Reactome: R-HSA-8931987|Reactome: R-HSA-9018519 MCR_1810 e2a15000e3d3851784317e04395c6bde 859 TIGRFAM TIGR03703 plsB: glycerol-3-phosphate O-acyltransferase 59 830 5.8E-256 T 14-10-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109|Reactome: R-HSA-8931987|Reactome: R-HSA-9018519 MCR_1810 e2a15000e3d3851784317e04395c6bde 859 PIRSF PIRSF000437 48 842 1.2E-211 T 14-10-2018 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 MCR_0675 0b6e2bc1dab170c716842f5722c7b7b0 782 Pfam PF10136 Site-specific recombinase 39 682 1.7E-228 T 14-10-2018 IPR011385 Putative site-specific recombinase Gcr MCR_0889 503415e9a254c223e31b9696df828dea 295 SUPERFAMILY SSF103481 47 144 2.22E-10 T 14-10-2018 MCR_0889 503415e9a254c223e31b9696df828dea 295 SUPERFAMILY SSF103481 209 284 1.44E-6 T 14-10-2018 MCR_0889 503415e9a254c223e31b9696df828dea 295 TIGRFAM TIGR00688 rarD: protein RarD 10 262 8.7E-58 T 14-10-2018 IPR004626 RarD protein GO:0005887 MCR_0889 503415e9a254c223e31b9696df828dea 295 Pfam PF00892 EamA-like transporter family 10 142 8.9E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MCR_0889 503415e9a254c223e31b9696df828dea 295 Pfam PF00892 EamA-like transporter family 157 285 3.4E-7 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MCR_0459 dccb88355b24adc1592acc6ca67da85c 427 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 426 3.0E-118 T 14-10-2018 IPR002155 Thiolase GO:0016747 MCR_0459 dccb88355b24adc1592acc6ca67da85c 427 Pfam PF02803 Thiolase, C-terminal domain 284 427 2.4E-31 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MCR_0459 dccb88355b24adc1592acc6ca67da85c 427 Pfam PF00108 Thiolase, N-terminal domain 6 272 3.6E-48 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MCR_0459 dccb88355b24adc1592acc6ca67da85c 427 Gene3D G3DSA:3.40.47.10 1 427 1.6E-103 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0459 dccb88355b24adc1592acc6ca67da85c 427 SUPERFAMILY SSF53901 280 427 7.34E-31 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0459 dccb88355b24adc1592acc6ca67da85c 427 PIRSF PIRSF000429 1 427 2.0E-103 T 14-10-2018 IPR002155 Thiolase GO:0016747 MCR_0459 dccb88355b24adc1592acc6ca67da85c 427 SUPERFAMILY SSF53901 6 280 8.52E-58 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MCR_0119 76fd33e6e477718dbfefd43cb880d03b 321 Gene3D G3DSA:1.20.1420.20 78 321 7.5E-83 T 14-10-2018 IPR038352 Imelysin-like domain superfamily MCR_0119 76fd33e6e477718dbfefd43cb880d03b 321 Pfam PF09375 Imelysin 86 316 1.1E-34 T 14-10-2018 IPR018976 Imelysin-like domain MCR_0655 3187d44eb01abc09f0faae99a1665174 220 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 24 178 9.3E-32 T 14-10-2018 IPR018639 Domain of unknown function DUF2062 MCR_1569 64ef1f2af22c3ebd9e3531f890c7ec44 116 Gene3D G3DSA:3.30.420.100 2 116 1.1E-40 T 14-10-2018 MCR_1569 64ef1f2af22c3ebd9e3531f890c7ec44 116 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 4 116 2.2E-40 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1569 64ef1f2af22c3ebd9e3531f890c7ec44 116 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 3 116 26.416 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1569 64ef1f2af22c3ebd9e3531f890c7ec44 116 SUPERFAMILY SSF53137 4 114 1.68E-49 T 14-10-2018 MCR_1569 64ef1f2af22c3ebd9e3531f890c7ec44 116 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 3 116 1.6E-41 T 14-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0158 ec9c059edc57b459cd418d5bfb6504ce 277 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 8 276 40.242 T 14-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 MCR_0158 ec9c059edc57b459cd418d5bfb6504ce 277 Pfam PF02666 Phosphatidylserine decarboxylase 61 273 1.9E-59 T 14-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MCR_0158 ec9c059edc57b459cd418d5bfb6504ce 277 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 47 274 3.0E-68 T 14-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MCR_1601 bb4c8b486a6a3d648a99760414868f49 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 14 42 1.0E-8 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1601 bb4c8b486a6a3d648a99760414868f49 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 14-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_1601 bb4c8b486a6a3d648a99760414868f49 71 Pfam PF01165 Ribosomal protein S21 3 55 2.0E-21 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1601 bb4c8b486a6a3d648a99760414868f49 71 Gene3D G3DSA:1.20.5.1150 16 54 5.9E-19 T 14-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1601 bb4c8b486a6a3d648a99760414868f49 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 20.672 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1601 bb4c8b486a6a3d648a99760414868f49 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 8.6E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1601 bb4c8b486a6a3d648a99760414868f49 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 8.6E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1601 bb4c8b486a6a3d648a99760414868f49 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 8.6E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1601 bb4c8b486a6a3d648a99760414868f49 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 8.6E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1601 bb4c8b486a6a3d648a99760414868f49 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 3.3E-22 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1588 0a1f8d0fcbda395c5ecf95ee7fe406b6 203 SUPERFAMILY SSF52972 5 195 2.81E-48 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MCR_1588 0a1f8d0fcbda395c5ecf95ee7fe406b6 203 Hamap MF_00528 Septum formation protein Maf [maf]. 8 201 25.835 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 MCR_1588 0a1f8d0fcbda395c5ecf95ee7fe406b6 203 TIGRFAM TIGR00172 maf: septum formation protein Maf 8 193 9.4E-42 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 MCR_1588 0a1f8d0fcbda395c5ecf95ee7fe406b6 203 Gene3D G3DSA:3.90.950.10 8 201 3.2E-56 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MCR_1588 0a1f8d0fcbda395c5ecf95ee7fe406b6 203 Pfam PF02545 Maf-like protein 9 196 1.3E-46 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 MCR_1588 0a1f8d0fcbda395c5ecf95ee7fe406b6 203 PIRSF PIRSF006305 1 203 3.6E-46 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 MCR_1491 72be40576286d47ebec93b3bed510828 280 ProSitePatterns PS00091 Thymidylate synthase active site. 142 170 - T 14-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MCR_1491 72be40576286d47ebec93b3bed510828 280 PRINTS PR00108 Thymidylate synthase family signature 42 63 9.2E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MCR_1491 72be40576286d47ebec93b3bed510828 280 PRINTS PR00108 Thymidylate synthase family signature 131 150 9.2E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MCR_1491 72be40576286d47ebec93b3bed510828 280 PRINTS PR00108 Thymidylate synthase family signature 157 172 9.2E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MCR_1491 72be40576286d47ebec93b3bed510828 280 PRINTS PR00108 Thymidylate synthase family signature 175 201 9.2E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MCR_1491 72be40576286d47ebec93b3bed510828 280 PRINTS PR00108 Thymidylate synthase family signature 213 230 9.2E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MCR_1491 72be40576286d47ebec93b3bed510828 280 Pfam PF00303 Thymidylate synthase 2 280 8.1E-117 T 14-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MCR_1491 72be40576286d47ebec93b3bed510828 280 Hamap MF_00008 Thymidylate synthase [thyA]. 1 280 38.808 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MCR_1491 72be40576286d47ebec93b3bed510828 280 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 280 5.4E-133 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MCR_1491 72be40576286d47ebec93b3bed510828 280 SUPERFAMILY SSF55831 1 280 5.23E-125 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MCR_1491 72be40576286d47ebec93b3bed510828 280 Gene3D G3DSA:3.30.572.10 1 280 1.6E-127 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MCR_0561 7ad1205eb104a32babd42d0cb7dc7dc9 172 Pfam PF04536 TPM domain 28 148 1.2E-11 T 14-10-2018 IPR007621 TPM domain MCR_0561 7ad1205eb104a32babd42d0cb7dc7dc9 172 Gene3D G3DSA:3.10.310.50 22 170 9.1E-45 T 14-10-2018 MCR_1434 5aad1d42996a5d3a0bd32fb34a80b8d9 178 Gene3D G3DSA:3.10.180.10 6 176 2.1E-55 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MCR_1434 5aad1d42996a5d3a0bd32fb34a80b8d9 178 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 20 176 3.9E-43 T 14-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MCR_1434 5aad1d42996a5d3a0bd32fb34a80b8d9 178 SUPERFAMILY SSF54593 27 174 1.65E-29 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MCR_1434 5aad1d42996a5d3a0bd32fb34a80b8d9 178 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 27 171 2.7E-18 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MCR_1434 5aad1d42996a5d3a0bd32fb34a80b8d9 178 ProSitePatterns PS00934 Glyoxalase I signature 1. 29 50 - T 14-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MCR_0295 f41fa9f7d22ac4243f680694674ab1ff 326 Gene3D G3DSA:3.40.190.10 113 317 1.1E-123 T 14-10-2018 MCR_0295 f41fa9f7d22ac4243f680694674ab1ff 326 PIRSF PIRSF002825 1 326 1.1E-96 T 14-10-2018 IPR026045 Ferric binding protein MCR_0295 f41fa9f7d22ac4243f680694674ab1ff 326 SUPERFAMILY SSF53850 14 318 1.65E-84 T 14-10-2018 MCR_0295 f41fa9f7d22ac4243f680694674ab1ff 326 Pfam PF13343 Bacterial extracellular solute-binding protein 64 288 4.5E-25 T 14-10-2018 MCR_0295 f41fa9f7d22ac4243f680694674ab1ff 326 Gene3D G3DSA:3.40.190.10 17 287 1.1E-123 T 14-10-2018 MCR_0164 d1289ed09687d564b6726818e9aae87f 150 SUPERFAMILY SSF69500 1 149 7.19E-48 T 14-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily MCR_0164 d1289ed09687d564b6726818e9aae87f 150 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 150 30.145 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MCR_0164 d1289ed09687d564b6726818e9aae87f 150 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 149 1.9E-46 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MCR_0164 d1289ed09687d564b6726818e9aae87f 150 Gene3D G3DSA:3.50.80.10 1 150 2.1E-48 T 14-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily MCR_0164 d1289ed09687d564b6726818e9aae87f 150 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 150 1.3E-44 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MCR_0296 8cae0de9beb97b5e3ab826a414a76e6c 394 SUPERFAMILY SSF55031 193 304 2.09E-28 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MCR_0296 8cae0de9beb97b5e3ab826a414a76e6c 394 Pfam PF07687 Peptidase dimerisation domain 189 295 1.0E-22 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain MCR_0296 8cae0de9beb97b5e3ab826a414a76e6c 394 Pfam PF01546 Peptidase family M20/M25/M40 76 389 3.3E-44 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MCR_0296 8cae0de9beb97b5e3ab826a414a76e6c 394 Gene3D G3DSA:3.30.70.360 193 310 4.8E-124 T 14-10-2018 MCR_0296 8cae0de9beb97b5e3ab826a414a76e6c 394 SUPERFAMILY SSF53187 7 392 1.75E-61 T 14-10-2018 MCR_0296 8cae0de9beb97b5e3ab826a414a76e6c 394 Gene3D G3DSA:3.40.630.10 12 381 4.8E-124 T 14-10-2018 MCR_0296 8cae0de9beb97b5e3ab826a414a76e6c 394 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 8 392 3.8E-157 T 14-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MCR_0296 8cae0de9beb97b5e3ab826a414a76e6c 394 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 4 394 50.413 T 14-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MCR_1415 e336908f57a05df674b64b101aebcf24 320 Gene3D G3DSA:3.40.1500.10 1 320 3.4E-128 T 14-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 174 198 - T 14-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 SUPERFAMILY SSF102886 4 314 1.31E-121 T 14-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 2 289 49.966 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 PIRSF PIRSF000166 1 315 1.5E-117 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 PRINTS PR00073 Coprogen oxidase signature 55 76 8.8E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 PRINTS PR00073 Coprogen oxidase signature 97 121 8.8E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 PRINTS PR00073 Coprogen oxidase signature 133 155 8.8E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 PRINTS PR00073 Coprogen oxidase signature 274 300 8.8E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 PRINTS PR00073 Coprogen oxidase signature 246 273 8.8E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 PRINTS PR00073 Coprogen oxidase signature 170 199 8.8E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 PRINTS PR00073 Coprogen oxidase signature 38 54 8.8E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1415 e336908f57a05df674b64b101aebcf24 320 Pfam PF01218 Coproporphyrinogen III oxidase 8 314 1.3E-118 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 397 36.097 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 14-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 Pfam PF00162 Phosphoglycerate kinase 7 387 5.2E-128 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 3.2E-77 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 3.2E-77 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 3.2E-77 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 317 342 3.2E-77 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 350 361 3.2E-77 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 373 390 3.2E-77 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 3.2E-77 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 3.2E-77 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 3.2E-77 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 SUPERFAMILY SSF53748 1 396 3.06E-126 T 14-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 Gene3D G3DSA:3.40.50.1260 10 393 1.2E-143 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 Gene3D G3DSA:3.40.50.1260 169 387 1.2E-143 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1030 e9cbe35a92ee57f3d394f4fc63a6862e 400 PIRSF PIRSF000724 1 400 5.3E-118 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1290 4c12a8cbb44b8d8191f3f32f08543b90 357 Gene3D G3DSA:3.40.1780.10 21 352 1.1E-111 T 14-10-2018 MCR_1290 4c12a8cbb44b8d8191f3f32f08543b90 357 Pfam PF02547 Queuosine biosynthesis protein 10 353 2.9E-127 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MCR_1290 4c12a8cbb44b8d8191f3f32f08543b90 357 SUPERFAMILY SSF111337 10 353 1.12E-123 T 14-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MCR_1290 4c12a8cbb44b8d8191f3f32f08543b90 357 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 10 353 4.6E-125 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MCR_1290 4c12a8cbb44b8d8191f3f32f08543b90 357 Gene3D G3DSA:2.40.10.240 69 171 1.1E-111 T 14-10-2018 MCR_1290 4c12a8cbb44b8d8191f3f32f08543b90 357 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 8 354 43.938 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MCR_1364 1ea1866eb1cfaa920ab8dc8d4b6b364a 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 284 1.5E-31 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 64 121 2.7E-23 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 316 328 7.8E-56 T 14-10-2018 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 247 273 7.8E-56 T 14-10-2018 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 82 107 7.8E-56 T 14-10-2018 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 225 246 7.8E-56 T 14-10-2018 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 110 130 7.8E-56 T 14-10-2018 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 157 178 7.8E-56 T 14-10-2018 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 419 438 7.8E-56 T 14-10-2018 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 2 612 9.7E-210 T 14-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 Pfam PF00361 Proton-conducting membrane transporter 133 426 1.2E-86 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 58 82 6.2E-13 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 359 381 6.2E-13 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 84 104 6.2E-13 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 418 440 6.2E-13 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MCR_0719 8c986e6066ada972acb44e414bd9d38a 617 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 265 287 6.2E-13 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MCR_0550 4787739e15dc5af848ed33771c7de8f7 500 SUPERFAMILY SSF161070 5 483 1.31E-135 T 14-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 MCR_0550 4787739e15dc5af848ed33771c7de8f7 500 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 29 43 - T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MCR_0550 4787739e15dc5af848ed33771c7de8f7 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 2.7E-25 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MCR_0550 4787739e15dc5af848ed33771c7de8f7 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 42 61 2.7E-25 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MCR_0550 4787739e15dc5af848ed33771c7de8f7 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 311 330 2.7E-25 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MCR_0550 4787739e15dc5af848ed33771c7de8f7 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 389 409 2.7E-25 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MCR_0550 4787739e15dc5af848ed33771c7de8f7 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 86 112 2.7E-25 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MCR_0550 4787739e15dc5af848ed33771c7de8f7 500 Pfam PF00209 Sodium:neurotransmitter symporter family 5 119 7.6E-39 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MCR_0550 4787739e15dc5af848ed33771c7de8f7 500 Pfam PF00209 Sodium:neurotransmitter symporter family 128 481 1.1E-69 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MCR_0438 88cfddf62db07db7ee6e6984c568e42b 262 SUPERFAMILY SSF69593 53 201 3.14E-21 T 14-10-2018 MCR_0438 88cfddf62db07db7ee6e6984c568e42b 262 SMART SM00563 78 189 2.7E-24 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MCR_0438 88cfddf62db07db7ee6e6984c568e42b 262 Pfam PF01553 Acyltransferase 65 186 7.3E-19 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MCR_0834 e9a87da04f05016e596e3a9df956eac3 366 Pfam PF03969 AFG1-like ATPase 5 361 4.6E-127 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 MCR_0834 e9a87da04f05016e596e3a9df956eac3 366 SUPERFAMILY SSF52540 60 231 7.79E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0834 e9a87da04f05016e596e3a9df956eac3 366 Hamap MF_01919 Cell division protein ZapE [zapE]. 4 365 49.454 T 14-10-2018 IPR030870 Cell division protein ZapE GO:0016887|GO:0051301 MCR_0834 e9a87da04f05016e596e3a9df956eac3 366 Gene3D G3DSA:3.40.50.300 25 193 5.3E-18 T 14-10-2018 MCR_0625 1689bdffe56ac232ac69aefe778cf1a6 814 PIRSF PIRSF002799 19 784 1.7E-285 T 14-10-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0625 1689bdffe56ac232ac69aefe778cf1a6 814 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 39 759 3.3E-242 T 14-10-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0625 1689bdffe56ac232ac69aefe778cf1a6 814 Pfam PF00905 Penicillin binding protein transpeptidase domain 444 689 1.1E-24 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MCR_0625 1689bdffe56ac232ac69aefe778cf1a6 814 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 183 715 3.0E-160 T 14-10-2018 MCR_0625 1689bdffe56ac232ac69aefe778cf1a6 814 Gene3D G3DSA:3.30.2060.10 82 170 5.3E-236 T 14-10-2018 MCR_0625 1689bdffe56ac232ac69aefe778cf1a6 814 Gene3D G3DSA:1.10.3810.10 171 374 5.3E-236 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0625 1689bdffe56ac232ac69aefe778cf1a6 814 SUPERFAMILY SSF53955 179 373 2.62E-68 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MCR_0625 1689bdffe56ac232ac69aefe778cf1a6 814 SUPERFAMILY SSF56601 332 781 1.65E-115 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MCR_0625 1689bdffe56ac232ac69aefe778cf1a6 814 Pfam PF14814 Bifunctional transglycosylase second domain 84 167 1.9E-16 T 14-10-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0625 1689bdffe56ac232ac69aefe778cf1a6 814 Pfam PF00912 Transglycosylase 181 350 2.2E-60 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0625 1689bdffe56ac232ac69aefe778cf1a6 814 Gene3D G3DSA:3.40.710.10 74 728 5.3E-236 T 14-10-2018 MCR_0569 d0d50405cbce628ba983669258574b63 353 Gene3D G3DSA:3.20.20.70 3 344 6.3E-112 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0569 d0d50405cbce628ba983669258574b63 353 SUPERFAMILY SSF51395 3 332 2.41E-103 T 14-10-2018 MCR_0569 d0d50405cbce628ba983669258574b63 353 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 334 3.0E-73 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MCR_0480 da0d4c156c8e20ffaee58dda92e28d7f 458 Gene3D G3DSA:3.40.50.300 259 444 9.9E-11 T 14-10-2018 MCR_0480 da0d4c156c8e20ffaee58dda92e28d7f 458 SUPERFAMILY SSF52540 8 400 3.26E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0480 da0d4c156c8e20ffaee58dda92e28d7f 458 Gene3D G3DSA:3.40.50.300 7 154 1.1E-7 T 14-10-2018 MCR_0480 da0d4c156c8e20ffaee58dda92e28d7f 458 Pfam PF13175 AAA ATPase domain 9 398 2.6E-22 T 14-10-2018 MCR_1143 49c5b283973215ed36693be250fea012 160 Gene3D G3DSA:3.10.129.10 6 159 8.1E-58 T 14-10-2018 MCR_1143 49c5b283973215ed36693be250fea012 160 SUPERFAMILY SSF54637 10 156 1.43E-45 T 14-10-2018 IPR029069 HotDog domain superfamily MCR_1143 49c5b283973215ed36693be250fea012 160 Pfam PF03061 Thioesterase superfamily 29 101 3.0E-17 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MCR_0023 c5212381c42bdd9e718f62fe851f8da2 210 SUPERFAMILY SSF58014 59 156 1.96E-22 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MCR_0023 c5212381c42bdd9e718f62fe851f8da2 210 PRINTS PR00773 GrpE protein signature 82 98 2.2E-24 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MCR_0023 c5212381c42bdd9e718f62fe851f8da2 210 PRINTS PR00773 GrpE protein signature 164 179 2.2E-24 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MCR_0023 c5212381c42bdd9e718f62fe851f8da2 210 PRINTS PR00773 GrpE protein signature 189 208 2.2E-24 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MCR_0023 c5212381c42bdd9e718f62fe851f8da2 210 PRINTS PR00773 GrpE protein signature 110 125 2.2E-24 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MCR_0023 c5212381c42bdd9e718f62fe851f8da2 210 ProSitePatterns PS01071 grpE protein signature. 167 208 - T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MCR_0023 c5212381c42bdd9e718f62fe851f8da2 210 Hamap MF_01151 Protein GrpE [grpE]. 25 210 18.625 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MCR_0023 c5212381c42bdd9e718f62fe851f8da2 210 Gene3D G3DSA:2.30.22.10 156 210 8.5E-17 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MCR_0023 c5212381c42bdd9e718f62fe851f8da2 210 SUPERFAMILY SSF51064 158 209 4.18E-14 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MCR_0023 c5212381c42bdd9e718f62fe851f8da2 210 Gene3D G3DSA:3.90.20.20 51 155 7.6E-23 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MCR_0023 c5212381c42bdd9e718f62fe851f8da2 210 Pfam PF01025 GrpE 54 209 2.9E-45 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MCR_1726 b48d0a746c19fac7efcfbeda47e10678 368 Pfam PF13343 Bacterial extracellular solute-binding protein 103 322 3.3E-32 T 14-10-2018 MCR_1726 b48d0a746c19fac7efcfbeda47e10678 368 Gene3D G3DSA:3.40.190.10 76 318 4.3E-31 T 14-10-2018 MCR_1726 b48d0a746c19fac7efcfbeda47e10678 368 SUPERFAMILY SSF53850 55 361 5.65E-45 T 14-10-2018 MCR_1726 b48d0a746c19fac7efcfbeda47e10678 368 Gene3D G3DSA:3.40.190.10 156 272 4.3E-31 T 14-10-2018 MCR_0596 d8ee052385113b70515ec08bdc1875c4 392 Gene3D G3DSA:2.30.30.280 231 299 6.9E-26 T 14-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MCR_0596 d8ee052385113b70515ec08bdc1875c4 392 SUPERFAMILY SSF52402 21 261 1.37E-51 T 14-10-2018 MCR_0596 d8ee052385113b70515ec08bdc1875c4 392 Gene3D G3DSA:2.40.30.10 300 391 6.3E-24 T 14-10-2018 MCR_0596 d8ee052385113b70515ec08bdc1875c4 392 Pfam PF03054 tRNA methyl transferase 21 384 2.4E-132 T 14-10-2018 MCR_0596 d8ee052385113b70515ec08bdc1875c4 392 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 21 384 2.6E-133 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MCR_0596 d8ee052385113b70515ec08bdc1875c4 392 Gene3D G3DSA:3.40.50.620 6 230 9.4E-89 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0596 d8ee052385113b70515ec08bdc1875c4 392 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 20 385 37.895 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MCR_1743 5b4b67356f2bf56df4c88998881e6ec0 169 Pfam PF02566 OsmC-like protein 68 164 7.0E-14 T 14-10-2018 IPR003718 OsmC/Ohr family MCR_1743 5b4b67356f2bf56df4c88998881e6ec0 169 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 36 165 1.4E-35 T 14-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 MCR_1743 5b4b67356f2bf56df4c88998881e6ec0 169 SUPERFAMILY SSF82784 24 165 1.31E-26 T 14-10-2018 IPR036102 OsmC/Ohr superfamily MCR_1743 5b4b67356f2bf56df4c88998881e6ec0 169 Gene3D G3DSA:3.30.300.20 25 168 4.8E-30 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MCR_0752 5b7cdbfd181f5031911e65d30b57fad5 223 Gene3D G3DSA:3.40.50.300 23 223 1.1E-48 T 14-10-2018 MCR_0752 5b7cdbfd181f5031911e65d30b57fad5 223 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0752 5b7cdbfd181f5031911e65d30b57fad5 223 SMART SM00382 40 219 5.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0752 5b7cdbfd181f5031911e65d30b57fad5 223 SUPERFAMILY SSF52540 31 223 2.48E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0752 5b7cdbfd181f5031911e65d30b57fad5 223 Pfam PF00005 ABC transporter 33 177 6.2E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1051 ff30a4b290f439e2a24874935c47e2d2 279 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 46 276 6.2E-53 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase MCR_1051 ff30a4b290f439e2a24874935c47e2d2 279 Gene3D G3DSA:3.60.140.10 32 279 6.4E-56 T 14-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily MCR_1051 ff30a4b290f439e2a24874935c47e2d2 279 SUPERFAMILY SSF64438 42 277 5.49E-55 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MCR_1014 451368904d4950de5370b157efdc912c 235 Pfam PF03466 LysR substrate binding domain 25 227 4.1E-32 T 14-10-2018 IPR005119 LysR, substrate-binding MCR_1014 451368904d4950de5370b157efdc912c 235 Gene3D G3DSA:3.40.190.290 26 231 5.3E-34 T 14-10-2018 MCR_1014 451368904d4950de5370b157efdc912c 235 SUPERFAMILY SSF53850 26 232 6.02E-35 T 14-10-2018 MCR_0858 55efd05be9a76c38864f155bddc21b30 459 Gene3D G3DSA:2.40.160.60 180 459 2.4E-20 T 14-10-2018 MCR_0858 55efd05be9a76c38864f155bddc21b30 459 SUPERFAMILY SSF56935 18 456 4.94E-51 T 14-10-2018 MCR_0858 55efd05be9a76c38864f155bddc21b30 459 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 60 433 2.9E-9 T 14-10-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) MCR_1335 2d0f2284c7270222d6e5f2dc13f8d10d 244 Pfam PF02678 Pirin 10 120 1.0E-32 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MCR_1335 2d0f2284c7270222d6e5f2dc13f8d10d 244 Gene3D G3DSA:2.60.120.10 8 234 4.1E-88 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MCR_1335 2d0f2284c7270222d6e5f2dc13f8d10d 244 SUPERFAMILY SSF51182 4 233 1.65E-70 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MCR_1335 2d0f2284c7270222d6e5f2dc13f8d10d 244 Gene3D G3DSA:2.60.120.10 12 136 4.1E-88 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MCR_1335 2d0f2284c7270222d6e5f2dc13f8d10d 244 PIRSF PIRSF006232 1 242 3.5E-47 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MCR_0587 56c04e9efcfea96e9bd0f3a8e0f108c8 485 Gene3D G3DSA:1.20.1250.20 1 475 8.5E-137 T 14-10-2018 MCR_0587 56c04e9efcfea96e9bd0f3a8e0f108c8 485 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 1 475 6.5E-101 T 14-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 MCR_0587 56c04e9efcfea96e9bd0f3a8e0f108c8 485 SUPERFAMILY SSF103473 2 284 6.54E-24 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_0587 56c04e9efcfea96e9bd0f3a8e0f108c8 485 Pfam PF00854 POT family 65 439 1.6E-62 T 14-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 MCR_0587 56c04e9efcfea96e9bd0f3a8e0f108c8 485 SUPERFAMILY SSF103473 310 469 1.57E-11 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_0587 56c04e9efcfea96e9bd0f3a8e0f108c8 485 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 128 140 - T 14-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MCR_1188 2d9d19cbec9e3e52f2057ecf8d02adaa 307 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 4 275 2.0E-37 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MCR_1188 2d9d19cbec9e3e52f2057ecf8d02adaa 307 PIRSF PIRSF026649 1 283 4.2E-61 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MCR_1877 0b5ca435786d6bdce7e83a170f0bfc30 369 Pfam PF09565 NgoFVII restriction endonuclease 216 317 3.2E-11 T 14-10-2018 IPR019065 Restriction endonuclease, type II, NgoFVII MCR_0166 09854374bc570ed655dd07c0bc7d8d38 260 Pfam PF00293 NUDIX domain 78 190 3.1E-7 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MCR_0166 09854374bc570ed655dd07c0bc7d8d38 260 SUPERFAMILY SSF55811 76 242 1.12E-21 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MCR_0166 09854374bc570ed655dd07c0bc7d8d38 260 Gene3D G3DSA:3.90.79.10 48 246 8.8E-36 T 14-10-2018 MCR_0413 a2ae512f6ec5679a295e61648eb4511f 374 SUPERFAMILY SSF52440 6 99 1.73E-15 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MCR_0413 a2ae512f6ec5679a295e61648eb4511f 374 Gene3D G3DSA:3.30.470.20 180 374 1.1E-71 T 14-10-2018 MCR_0413 a2ae512f6ec5679a295e61648eb4511f 374 Pfam PF02222 ATP-grasp domain 109 289 1.5E-55 T 14-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MCR_0413 a2ae512f6ec5679a295e61648eb4511f 374 SUPERFAMILY SSF51246 313 370 1.88E-14 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MCR_0413 a2ae512f6ec5679a295e61648eb4511f 374 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 7 363 2.6E-106 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MCR_0413 a2ae512f6ec5679a295e61648eb4511f 374 SUPERFAMILY SSF56059 100 309 4.42E-63 T 14-10-2018 MCR_0413 a2ae512f6ec5679a295e61648eb4511f 374 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 7 361 39.12 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MCR_0413 a2ae512f6ec5679a295e61648eb4511f 374 Gene3D G3DSA:3.30.1490.20 105 175 1.3E-26 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MCR_0413 a2ae512f6ec5679a295e61648eb4511f 374 Gene3D G3DSA:3.40.50.20 3 104 4.7E-25 T 14-10-2018 MCR_1150 71fd0a293f0fab11744fe24b5580f85a 494 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 72 492 3.4E-113 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 MCR_1150 71fd0a293f0fab11744fe24b5580f85a 494 Pfam PF00939 Sodium:sulfate symporter transmembrane region 57 488 1.1E-51 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 MCR_1261 01694213b577a33e1d15e0dad2c2181d 372 Pfam PF07690 Major Facilitator Superfamily 2 334 2.3E-27 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MCR_1261 01694213b577a33e1d15e0dad2c2181d 372 Gene3D G3DSA:1.20.1250.20 1 371 7.6E-42 T 14-10-2018 MCR_1261 01694213b577a33e1d15e0dad2c2181d 372 ProSitePatterns PS00216 Sugar transport proteins signature 1. 49 65 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MCR_1261 01694213b577a33e1d15e0dad2c2181d 372 SUPERFAMILY SSF103473 2 370 3.4E-48 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_1835 e2df8f6f79ae5a570f8fffd52b0c5b0a 162 SUPERFAMILY SSF55083 1 153 1.24E-44 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MCR_1835 e2df8f6f79ae5a570f8fffd52b0c5b0a 162 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 136 1.3E-34 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MCR_1835 e2df8f6f79ae5a570f8fffd52b0c5b0a 162 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 136 8.6E-31 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MCR_1835 e2df8f6f79ae5a570f8fffd52b0c5b0a 162 Gene3D G3DSA:3.30.70.560 1 159 9.8E-45 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MCR_1835 e2df8f6f79ae5a570f8fffd52b0c5b0a 162 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 92 103 - T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MCR_0369 a242fe26b5576a77c28b983aba23b447 277 Gene3D G3DSA:3.60.21.10 3 275 7.1E-53 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like MCR_0369 a242fe26b5576a77c28b983aba23b447 277 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 10 265 38.625 T 14-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 MCR_0369 a242fe26b5576a77c28b983aba23b447 277 SUPERFAMILY SSF56300 8 264 4.64E-46 T 14-10-2018 MCR_0369 a242fe26b5576a77c28b983aba23b447 277 Pfam PF00149 Calcineurin-like phosphoesterase 10 207 6.3E-16 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MCR_0659 b56f1150d195b80109802d646569365b 169 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 14-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MCR_0659 b56f1150d195b80109802d646569365b 169 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 6 166 4.3E-49 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MCR_0659 b56f1150d195b80109802d646569365b 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 122 137 1.5E-11 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MCR_0659 b56f1150d195b80109802d646569365b 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 1.5E-11 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MCR_0659 b56f1150d195b80109802d646569365b 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 1.5E-11 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MCR_0659 b56f1150d195b80109802d646569365b 169 SUPERFAMILY SSF50891 6 167 1.46E-58 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily MCR_0659 b56f1150d195b80109802d646569365b 169 PIRSF PIRSF001467 1 169 2.1E-27 T 14-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 MCR_0659 b56f1150d195b80109802d646569365b 169 Gene3D G3DSA:2.40.100.10 2 167 1.2E-67 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily MCR_1272 c5479edfdf6ac9a8c0d040c06cc69972 181 SUPERFAMILY SSF52218 4 173 6.11E-36 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MCR_1272 c5479edfdf6ac9a8c0d040c06cc69972 181 Pfam PF03358 NADPH-dependent FMN reductase 5 142 2.8E-28 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MCR_1272 c5479edfdf6ac9a8c0d040c06cc69972 181 Gene3D G3DSA:3.40.50.360 1 180 9.9E-39 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MCR_1625 43e7428cab9183135c10fed100bb8f9f 420 PIRSF PIRSF000412 2 418 6.8E-168 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MCR_1625 43e7428cab9183135c10fed100bb8f9f 420 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MCR_1625 43e7428cab9183135c10fed100bb8f9f 420 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 6 416 52.194 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MCR_1625 43e7428cab9183135c10fed100bb8f9f 420 Pfam PF00464 Serine hydroxymethyltransferase 7 385 3.8E-179 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MCR_1625 43e7428cab9183135c10fed100bb8f9f 420 SUPERFAMILY SSF53383 6 415 3.3E-179 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_1625 43e7428cab9183135c10fed100bb8f9f 420 Gene3D G3DSA:3.90.1150.10 9 392 2.5E-187 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_1625 43e7428cab9183135c10fed100bb8f9f 420 Gene3D G3DSA:3.40.640.10 36 288 2.5E-187 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_1382 2d7bbf4d1c0d123d6ef9cd2d118bd329 333 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 30 2.0E-4 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site MCR_1675 2edcb8c6af6edbc5120f332c60f5802b 465 SUPERFAMILY SSF58113 326 458 8.5E-6 T 14-10-2018 MCR_1675 2edcb8c6af6edbc5120f332c60f5802b 465 Pfam PF01618 MotA/TolQ/ExbB proton channel family 44 119 1.9E-8 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MCR_1675 2edcb8c6af6edbc5120f332c60f5802b 465 Gene3D G3DSA:1.20.120.20 306 459 1.3E-5 T 14-10-2018 MCR_1763 b13d3d17871aac48fa9c6f7d015dd296 141 SUPERFAMILY SSF89919 2 109 1.44E-29 T 14-10-2018 IPR023799 Ribosome-binding factor A domain superfamily MCR_1763 b13d3d17871aac48fa9c6f7d015dd296 141 Gene3D G3DSA:3.30.300.20 1 110 3.4E-33 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MCR_1763 b13d3d17871aac48fa9c6f7d015dd296 141 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 115 23.514 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MCR_1763 b13d3d17871aac48fa9c6f7d015dd296 141 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 6 102 6.0E-40 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MCR_1763 b13d3d17871aac48fa9c6f7d015dd296 141 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 117 8.3E-25 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MCR_1763 b13d3d17871aac48fa9c6f7d015dd296 141 Pfam PF02033 Ribosome-binding factor A 4 114 3.0E-29 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MCR_1655 8bf9a924677cf0434eff3b347fb81be0 203 Gene3D G3DSA:3.30.300.130 112 202 2.5E-19 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MCR_1655 8bf9a924677cf0434eff3b347fb81be0 203 Gene3D G3DSA:2.60.300.12 7 106 9.0E-13 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MCR_1655 8bf9a924677cf0434eff3b347fb81be0 203 TIGRFAM TIGR03341 YhgI_GntY: IscR-regulated protein YhgI 9 202 8.7E-90 T 14-10-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 MCR_1655 8bf9a924677cf0434eff3b347fb81be0 203 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 126 189 5.0E-24 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MCR_1655 8bf9a924677cf0434eff3b347fb81be0 203 SUPERFAMILY SSF117916 103 194 2.18E-20 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MCR_1655 8bf9a924677cf0434eff3b347fb81be0 203 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 8 202 40.216 T 14-10-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 MCR_1655 8bf9a924677cf0434eff3b347fb81be0 203 Pfam PF01106 NifU-like domain 119 189 2.1E-19 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MCR_1655 8bf9a924677cf0434eff3b347fb81be0 203 Pfam PF01521 Iron-sulphur cluster biosynthesis 8 104 1.5E-11 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MCR_1655 8bf9a924677cf0434eff3b347fb81be0 203 SUPERFAMILY SSF89360 5 102 1.0E-21 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MCR_0489 267b6cf57d65e4a561484876c639198b 267 SUPERFAMILY SSF52833 123 260 8.5E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0489 267b6cf57d65e4a561484876c639198b 267 SUPERFAMILY SSF54423 58 111 1.47E-5 T 14-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 MCR_0489 267b6cf57d65e4a561484876c639198b 267 Gene3D G3DSA:3.40.30.10 113 265 8.1E-41 T 14-10-2018 MCR_0489 267b6cf57d65e4a561484876c639198b 267 Pfam PF13098 Thioredoxin-like domain 143 260 6.4E-22 T 14-10-2018 IPR012336 Thioredoxin-like fold MCR_0489 267b6cf57d65e4a561484876c639198b 267 Pfam PF10411 Disulfide bond isomerase protein N-terminus 58 108 4.6E-10 T 14-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal MCR_1739 ce5265b535fe570e9a121f576b1b5638 242 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 73 87 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1739 ce5265b535fe570e9a121f576b1b5638 242 Pfam PF00849 RNA pseudouridylate synthase 38 191 1.4E-27 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1739 ce5265b535fe570e9a121f576b1b5638 242 Gene3D G3DSA:3.30.2350.10 25 241 5.1E-55 T 14-10-2018 MCR_1739 ce5265b535fe570e9a121f576b1b5638 242 SUPERFAMILY SSF55120 28 241 1.76E-51 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0447 f3e625842bb3fc28d73de21a6fc74d02 71 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 14 57 8.4E-11 T 14-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type MCR_0447 f3e625842bb3fc28d73de21a6fc74d02 71 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 14 56 1.1E-15 T 14-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type MCR_0499 50041d13cae48b08ce1de0f70622cd59 170 Pfam PF01252 Signal peptidase (SPase) II 18 162 1.2E-38 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MCR_0499 50041d13cae48b08ce1de0f70622cd59 170 TIGRFAM TIGR00077 lspA: signal peptidase II 9 167 1.8E-44 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MCR_0499 50041d13cae48b08ce1de0f70622cd59 170 ProSitePatterns PS00855 Signal peptidases II signature. 108 120 - T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MCR_0499 50041d13cae48b08ce1de0f70622cd59 170 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 10 167 17.696 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MCR_0499 50041d13cae48b08ce1de0f70622cd59 170 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 142 158 4.3E-17 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MCR_0499 50041d13cae48b08ce1de0f70622cd59 170 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 57 65 4.3E-17 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MCR_0499 50041d13cae48b08ce1de0f70622cd59 170 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 105 120 4.3E-17 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 Pfam PF13432 Tetratricopeptide repeat 393 439 0.0083 T 14-10-2018 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 SMART SM00028 595 628 330.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 SMART SM00028 484 517 190.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 SMART SM00028 281 314 10.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 SMART SM00028 416 449 3.7 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 SMART SM00028 216 249 59.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 SUPERFAMILY SSF48452 213 444 2.2E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 Gene3D G3DSA:1.25.40.10 380 446 2.1E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 SUPERFAMILY SSF48452 152 269 2.54E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 Gene3D G3DSA:1.25.40.10 458 666 9.1E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 Gene3D G3DSA:1.25.40.10 146 379 9.9E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0187 f96af9ffe2d5c43713cac199ddfe1be2 671 SUPERFAMILY SSF81901 388 616 2.12E-9 T 14-10-2018 MCR_0265 617c2231961b72b455fc518ac2b91d5d 52 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 49 15.702 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 MCR_0265 617c2231961b72b455fc518ac2b91d5d 52 PIRSF PIRSF036466 1 52 9.4E-17 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 MCR_0265 617c2231961b72b455fc518ac2b91d5d 52 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 2.0E-10 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 MCR_1305 45462df5dd97b1626e8c896c46946f30 336 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1305 45462df5dd97b1626e8c896c46946f30 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 224 309 1.3E-16 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MCR_1305 45462df5dd97b1626e8c896c46946f30 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 226 288 2.0E-9 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MCR_1305 45462df5dd97b1626e8c896c46946f30 336 SMART SM00382 24 224 1.1E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1305 45462df5dd97b1626e8c896c46946f30 336 SUPERFAMILY SSF52540 3 245 6.23E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1305 45462df5dd97b1626e8c896c46946f30 336 Gene3D G3DSA:3.40.50.300 1 323 7.7E-87 T 14-10-2018 MCR_1305 45462df5dd97b1626e8c896c46946f30 336 Pfam PF00005 ABC transporter 16 174 2.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0345 1e83a8cc590335c31c08c55c4575c906 242 Pfam PF05857 TraX protein 14 238 9.0E-32 T 14-10-2018 IPR008875 TraX MCR_0754 5457c58dfd82bf5d5a9ca70c9b258759 254 SUPERFAMILY SSF53850 27 251 9.32E-65 T 14-10-2018 MCR_0754 5457c58dfd82bf5d5a9ca70c9b258759 254 Gene3D G3DSA:3.40.190.10 29 251 3.0E-77 T 14-10-2018 MCR_0754 5457c58dfd82bf5d5a9ca70c9b258759 254 Pfam PF13531 Bacterial extracellular solute-binding protein 28 251 2.0E-44 T 14-10-2018 MCR_0754 5457c58dfd82bf5d5a9ca70c9b258759 254 Gene3D G3DSA:3.40.190.10 106 217 3.0E-77 T 14-10-2018 MCR_0754 5457c58dfd82bf5d5a9ca70c9b258759 254 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 33 250 1.3E-64 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 MCR_0754 5457c58dfd82bf5d5a9ca70c9b258759 254 PIRSF PIRSF004846 1 254 9.6E-75 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 MCR_1383 5a42174bb6e16109c15c514541cab9a2 196 Pfam PF07963 Prokaryotic N-terminal methylation motif 24 47 2.7E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site MCR_1793 070b52ee220adca4d4ed8d2a20358748 128 Gene3D G3DSA:3.40.50.150 40 118 1.6E-5 T 14-10-2018 MCR_0241 bb155f9ad350e1494d4f35ff44434231 106 SUPERFAMILY SSF102705 2 101 2.94E-25 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily MCR_0241 bb155f9ad350e1494d4f35ff44434231 106 Gene3D G3DSA:3.30.70.120 1 104 2.7E-41 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MCR_1101 0f7aa773f7f4c05f8f5953349c15d1c1 377 Hamap MF_01850 tRNA-cytidine(32) 2-sulfurtransferase [ttcA]. 51 312 54.683 T 14-10-2018 IPR012089 tRNA-cytidine(32) 2-sulfurtransferase GO:0008033 MCR_1101 0f7aa773f7f4c05f8f5953349c15d1c1 377 Gene3D G3DSA:3.40.50.620 55 306 5.1E-42 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_1101 0f7aa773f7f4c05f8f5953349c15d1c1 377 Pfam PF01171 PP-loop family 83 246 5.9E-13 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MCR_1101 0f7aa773f7f4c05f8f5953349c15d1c1 377 SUPERFAMILY SSF52402 58 274 3.03E-51 T 14-10-2018 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 PIRSF PIRSF001400 8 434 9.4E-189 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 SMART SM01193 12 142 3.0E-86 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 12 433 9.1E-199 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 SUPERFAMILY SSF51604 150 424 5.52E-124 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 Gene3D G3DSA:3.20.20.120 136 436 2.4E-133 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 SUPERFAMILY SSF54826 12 145 3.09E-54 T 14-10-2018 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 Hamap MF_00318 Enolase [eno]. 10 423 43.711 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 PRINTS PR00148 Enolase signature 172 185 4.5E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 PRINTS PR00148 Enolase signature 323 334 4.5E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 PRINTS PR00148 Enolase signature 115 131 4.5E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 PRINTS PR00148 Enolase signature 375 392 4.5E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 PRINTS PR00148 Enolase signature 45 59 4.5E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 PRINTS PR00148 Enolase signature 346 360 4.5E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 Pfam PF00113 Enolase, C-terminal TIM barrel domain 151 431 3.1E-131 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 ProSitePatterns PS00164 Enolase signature. 346 359 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 Pfam PF03952 Enolase, N-terminal domain 12 142 7.0E-57 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 Gene3D G3DSA:3.30.390.10 9 134 1.4E-53 T 14-10-2018 IPR029017 Enolase-like, N-terminal MCR_1317 1ba306a91440909187c00e2f4aac03b1 438 SMART SM01192 150 435 1.6E-209 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MCR_1069 6e7e996ec18e997cf1e5048f44cfb3cc 386 Pfam PF13439 Glycosyltransferase Family 4 16 149 3.7E-12 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MCR_1069 6e7e996ec18e997cf1e5048f44cfb3cc 386 SUPERFAMILY SSF53756 2 380 1.26E-38 T 14-10-2018 MCR_1069 6e7e996ec18e997cf1e5048f44cfb3cc 386 Gene3D G3DSA:3.40.50.2000 175 364 2.3E-35 T 14-10-2018 MCR_1069 6e7e996ec18e997cf1e5048f44cfb3cc 386 Pfam PF00534 Glycosyl transferases group 1 202 356 8.6E-14 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MCR_1069 6e7e996ec18e997cf1e5048f44cfb3cc 386 Gene3D G3DSA:3.40.50.2000 23 377 2.3E-35 T 14-10-2018 MCR_0325 c1316fb1bba1cd102f849490048bb149 321 Hamap MF_00323 Ferrochelatase [hemH]. 2 321 37.111 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MCR_0325 c1316fb1bba1cd102f849490048bb149 321 Gene3D G3DSA:3.40.50.1400 165 302 6.0E-95 T 14-10-2018 MCR_0325 c1316fb1bba1cd102f849490048bb149 321 Gene3D G3DSA:3.40.50.1400 4 319 6.0E-95 T 14-10-2018 MCR_0325 c1316fb1bba1cd102f849490048bb149 321 TIGRFAM TIGR00109 hemH: ferrochelatase 1 320 1.5E-97 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MCR_0325 c1316fb1bba1cd102f849490048bb149 321 SUPERFAMILY SSF53800 1 320 7.33E-99 T 14-10-2018 MCR_0325 c1316fb1bba1cd102f849490048bb149 321 ProSitePatterns PS00534 Ferrochelatase signature. 191 209 - T 14-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MCR_0325 c1316fb1bba1cd102f849490048bb149 321 Pfam PF00762 Ferrochelatase 3 319 8.3E-106 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MCR_0004 2080630c4bdd7697d815c0b4de847bdf 402 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 360 5.8E-68 T 14-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MCR_0004 2080630c4bdd7697d815c0b4de847bdf 402 Gene3D G3DSA:1.20.1050.90 121 319 1.5E-66 T 14-10-2018 MCR_0004 2080630c4bdd7697d815c0b4de847bdf 402 Gene3D G3DSA:3.40.50.300 5 353 1.5E-66 T 14-10-2018 MCR_0004 2080630c4bdd7697d815c0b4de847bdf 402 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 402 64.738 T 14-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MCR_0004 2080630c4bdd7697d815c0b4de847bdf 402 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 361 5.2E-22 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal MCR_0004 2080630c4bdd7697d815c0b4de847bdf 402 SUPERFAMILY SSF52540 1 365 2.33E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1818 bed34a931996f8dc65474001ed46722a 398 PRINTS PR00799 Aspartate aminotransferase signature 176 195 3.9E-34 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MCR_1818 bed34a931996f8dc65474001ed46722a 398 PRINTS PR00799 Aspartate aminotransferase signature 207 219 3.9E-34 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MCR_1818 bed34a931996f8dc65474001ed46722a 398 PRINTS PR00799 Aspartate aminotransferase signature 274 299 3.9E-34 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MCR_1818 bed34a931996f8dc65474001ed46722a 398 PRINTS PR00799 Aspartate aminotransferase signature 342 360 3.9E-34 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MCR_1818 bed34a931996f8dc65474001ed46722a 398 Gene3D G3DSA:3.90.1150.10 5 393 4.6E-152 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_1818 bed34a931996f8dc65474001ed46722a 398 Gene3D G3DSA:3.40.640.10 61 301 4.6E-152 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_1818 bed34a931996f8dc65474001ed46722a 398 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MCR_1818 bed34a931996f8dc65474001ed46722a 398 Pfam PF00155 Aminotransferase class I and II 28 392 6.4E-76 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MCR_1818 bed34a931996f8dc65474001ed46722a 398 SUPERFAMILY SSF53383 1 398 2.3E-113 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0748 d6e8f3acc590dc110dafb4a21b2d83d2 266 SUPERFAMILY SSF89155 9 176 2.75E-27 T 14-10-2018 IPR036411 TorD-like superfamily MCR_0748 d6e8f3acc590dc110dafb4a21b2d83d2 266 Gene3D G3DSA:1.10.4070.10 77 163 1.3E-11 T 14-10-2018 MCR_0748 d6e8f3acc590dc110dafb4a21b2d83d2 266 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 14 174 1.5E-33 T 14-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 MCR_0748 d6e8f3acc590dc110dafb4a21b2d83d2 266 Gene3D G3DSA:1.20.120.700 10 164 1.3E-11 T 14-10-2018 MCR_0748 d6e8f3acc590dc110dafb4a21b2d83d2 266 Pfam PF02613 Nitrate reductase delta subunit 43 171 1.4E-13 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone MCR_1008 f51e5051a7146d80d587bd0503e6b37e 625 SUPERFAMILY SSF82866 330 617 8.5E-44 T 14-10-2018 MCR_1008 f51e5051a7146d80d587bd0503e6b37e 625 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 347 602 8.6E-71 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MCR_1008 f51e5051a7146d80d587bd0503e6b37e 625 Gene3D G3DSA:3.30.1360.200 280 440 7.5E-44 T 14-10-2018 MCR_1008 f51e5051a7146d80d587bd0503e6b37e 625 Gene3D G3DSA:1.20.1640.10 448 621 2.4E-15 T 14-10-2018 MCR_1008 f51e5051a7146d80d587bd0503e6b37e 625 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 623 46.472 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MCR_1008 f51e5051a7146d80d587bd0503e6b37e 625 Pfam PF02355 Protein export membrane protein 445 612 7.9E-21 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MCR_1008 f51e5051a7146d80d587bd0503e6b37e 625 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 122 609 2.6E-133 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MCR_1008 f51e5051a7146d80d587bd0503e6b37e 625 Pfam PF07549 SecD/SecF GG Motif 116 139 6.1E-6 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MCR_1008 f51e5051a7146d80d587bd0503e6b37e 625 Gene3D G3DSA:3.30.70.3400 220 446 7.5E-44 T 14-10-2018 MCR_1008 f51e5051a7146d80d587bd0503e6b37e 625 Pfam PF13721 SecD export protein N-terminal TM region 2 102 1.9E-33 T 14-10-2018 IPR027398 SecD export protein N-terminal TM domain MCR_0355 fd74118c42988fd3b374dd3adba697ad 589 Gene3D G3DSA:2.40.50.460 462 585 4.2E-9 T 14-10-2018 MCR_0355 fd74118c42988fd3b374dd3adba697ad 589 Gene3D G3DSA:3.90.1640.30 55 327 9.3E-87 T 14-10-2018 MCR_0355 fd74118c42988fd3b374dd3adba697ad 589 Pfam PF01368 DHH family 80 187 6.9E-9 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MCR_0355 fd74118c42988fd3b374dd3adba697ad 589 SUPERFAMILY SSF64182 59 460 2.09E-105 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily MCR_0355 fd74118c42988fd3b374dd3adba697ad 589 Gene3D G3DSA:3.10.310.30 330 461 2.3E-31 T 14-10-2018 MCR_0355 fd74118c42988fd3b374dd3adba697ad 589 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 32 579 8.9E-139 T 14-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 MCR_0355 fd74118c42988fd3b374dd3adba697ad 589 Pfam PF02272 DHHA1 domain 323 459 4.5E-23 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MCR_0210 2988483dca9818024dd4093723a215ec 233 Gene3D G3DSA:3.30.70.1400 6 88 4.1E-17 T 14-10-2018 MCR_0210 2988483dca9818024dd4093723a215ec 233 SUPERFAMILY SSF103025 2 164 1.22E-32 T 14-10-2018 MCR_0210 2988483dca9818024dd4093723a215ec 233 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 112 175 1.8E-19 T 14-10-2018 IPR017703 YgfZ/GcvT conserved site MCR_0210 2988483dca9818024dd4093723a215ec 233 Gene3D G3DSA:2.40.30.160 121 224 1.0E-15 T 14-10-2018 MCR_0513 26ef14ecc860454289baf3c14af7674f 195 SMART SM00644 20 178 3.0E-39 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MCR_0513 26ef14ecc860454289baf3c14af7674f 195 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 36 178 5.4E-25 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MCR_0513 26ef14ecc860454289baf3c14af7674f 195 Gene3D G3DSA:3.40.80.10 5 194 3.2E-54 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MCR_0513 26ef14ecc860454289baf3c14af7674f 195 SUPERFAMILY SSF55846 7 192 3.14E-54 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MCR_1040 10589edd51530aaac547c3596c627f63 64 Gene3D G3DSA:1.10.10.1100 1 56 7.3E-19 T 14-10-2018 MCR_1040 10589edd51530aaac547c3596c627f63 64 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 51 4.8E-11 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MCR_1436 97c4b86ed14759fb3ca19440de459888 314 Gene3D G3DSA:3.30.70.1070 94 183 6.0E-9 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MCR_0379 da7531889b64952885c7c0a477b7a99b 182 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 182 19.957 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0379 da7531889b64952885c7c0a477b7a99b 182 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 8 180 2.1E-44 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0379 da7531889b64952885c7c0a477b7a99b 182 SUPERFAMILY SSF47928 3 106 1.19E-23 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0379 da7531889b64952885c7c0a477b7a99b 182 PRINTS PR00125 ATP synthase delta subunit signature 90 104 1.7E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0379 da7531889b64952885c7c0a477b7a99b 182 PRINTS PR00125 ATP synthase delta subunit signature 155 173 1.7E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0379 da7531889b64952885c7c0a477b7a99b 182 PRINTS PR00125 ATP synthase delta subunit signature 79 90 1.7E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0379 da7531889b64952885c7c0a477b7a99b 182 PRINTS PR00125 ATP synthase delta subunit signature 7 26 1.7E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0379 da7531889b64952885c7c0a477b7a99b 182 PRINTS PR00125 ATP synthase delta subunit signature 140 155 1.7E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0379 da7531889b64952885c7c0a477b7a99b 182 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 142 161 - T 14-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0379 da7531889b64952885c7c0a477b7a99b 182 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 180 5.6E-55 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0379 da7531889b64952885c7c0a477b7a99b 182 Gene3D G3DSA:1.10.520.20 2 110 1.6E-29 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0307 68187913796c9923e1cede4b0e04550d 432 Gene3D G3DSA:3.30.420.40 195 348 5.8E-56 T 14-10-2018 MCR_0307 68187913796c9923e1cede4b0e04550d 432 SUPERFAMILY SSF53067 197 350 2.25E-24 T 14-10-2018 MCR_0307 68187913796c9923e1cede4b0e04550d 432 Gene3D G3DSA:3.90.640.10 233 297 5.8E-56 T 14-10-2018 MCR_0307 68187913796c9923e1cede4b0e04550d 432 Gene3D G3DSA:3.30.1490.110 82 167 5.8E-56 T 14-10-2018 MCR_0307 68187913796c9923e1cede4b0e04550d 432 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 349 7.1E-56 T 14-10-2018 IPR020823 Cell division protein FtsA MCR_0307 68187913796c9923e1cede4b0e04550d 432 PIRSF PIRSF003101 2 432 6.2E-63 T 14-10-2018 IPR020823 Cell division protein FtsA MCR_0307 68187913796c9923e1cede4b0e04550d 432 SMART SM00842 4 194 2.9E-14 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 MCR_0307 68187913796c9923e1cede4b0e04550d 432 SUPERFAMILY SSF53067 5 195 4.08E-13 T 14-10-2018 MCR_0307 68187913796c9923e1cede4b0e04550d 432 Pfam PF14450 Cell division protein FtsA 206 347 9.9E-11 T 14-10-2018 MCR_0307 68187913796c9923e1cede4b0e04550d 432 Gene3D G3DSA:3.30.420.40 7 356 5.8E-56 T 14-10-2018 MCR_1005 f7f3bb1f409dcde6924dddf25fb2ce83 185 Pfam PF14534 Domain of unknown function (DUF4440) 71 169 6.9E-7 T 14-10-2018 IPR027843 Domain of unknown function DUF4440 MCR_1005 f7f3bb1f409dcde6924dddf25fb2ce83 185 SUPERFAMILY SSF54427 65 166 4.65E-8 T 14-10-2018 IPR032710 NTF2-like domain superfamily MCR_1005 f7f3bb1f409dcde6924dddf25fb2ce83 185 Gene3D G3DSA:3.10.450.50 49 172 1.4E-7 T 14-10-2018 MCR_0266 d207e7e5cd2274dfa3e615086f4ddca8 265 Pfam PF01925 Sulfite exporter TauE/SafE 7 260 1.3E-50 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MCR_0001 e4dca035059da2d947f9edda9d4163f3 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 14-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0001 e4dca035059da2d947f9edda9d4163f3 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 8.4E-27 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0001 e4dca035059da2d947f9edda9d4163f3 44 Pfam PF00468 Ribosomal protein L34 1 44 8.3E-25 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0001 e4dca035059da2d947f9edda9d4163f3 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.4 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0001 e4dca035059da2d947f9edda9d4163f3 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 39 8.0E-14 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1567 1ce8baeda7bf72813eb7581277b02c17 59 Pfam PF00327 Ribosomal protein L30p/L7e 5 54 8.8E-17 T 14-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MCR_1567 1ce8baeda7bf72813eb7581277b02c17 59 Gene3D G3DSA:3.30.1390.20 1 59 9.0E-25 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily MCR_1567 1ce8baeda7bf72813eb7581277b02c17 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.1E-21 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1567 1ce8baeda7bf72813eb7581277b02c17 59 SUPERFAMILY SSF55129 1 58 4.71E-21 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily MCR_1567 1ce8baeda7bf72813eb7581277b02c17 59 PIRSF PIRSF002211 1 59 1.7E-26 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1567 1ce8baeda7bf72813eb7581277b02c17 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 20.308 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 26 148 38.79 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 Pfam PF00164 Ribosomal protein S12/S23 38 148 6.2E-42 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 PRINTS PR01034 Ribosomal protein S12 signature 83 102 7.5E-60 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 PRINTS PR01034 Ribosomal protein S12 signature 67 82 7.5E-60 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 PRINTS PR01034 Ribosomal protein S12 signature 102 119 7.5E-60 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 PRINTS PR01034 Ribosomal protein S12 signature 135 147 7.5E-60 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 PRINTS PR01034 Ribosomal protein S12 signature 52 67 7.5E-60 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 PRINTS PR01034 Ribosomal protein S12 signature 119 135 7.5E-60 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 PIRSF PIRSF002133 26 149 1.4E-53 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 26 149 1.9E-68 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 ProSitePatterns PS00055 Ribosomal protein S12 signature. 68 75 - T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 Gene3D G3DSA:2.40.50.140 24 149 7.4E-63 T 14-10-2018 MCR_0226 f44221168cb5f98ae5a66c4c7080b276 149 SUPERFAMILY SSF50249 28 148 7.37E-51 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0517 a37a513820891435434515908ccc5813 975 PRINTS PR00986 Valyl-tRNA synthetase signature 476 497 5.1E-36 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MCR_0517 a37a513820891435434515908ccc5813 975 PRINTS PR00986 Valyl-tRNA synthetase signature 513 531 5.1E-36 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MCR_0517 a37a513820891435434515908ccc5813 975 PRINTS PR00986 Valyl-tRNA synthetase signature 44 55 5.1E-36 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MCR_0517 a37a513820891435434515908ccc5813 975 PRINTS PR00986 Valyl-tRNA synthetase signature 245 262 5.1E-36 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MCR_0517 a37a513820891435434515908ccc5813 975 PRINTS PR00986 Valyl-tRNA synthetase signature 377 390 5.1E-36 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MCR_0517 a37a513820891435434515908ccc5813 975 SUPERFAMILY SSF47323 655 923 3.18E-65 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0517 a37a513820891435434515908ccc5813 975 TIGRFAM TIGR00422 valS: valine--tRNA ligase 8 955 0.0 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MCR_0517 a37a513820891435434515908ccc5813 975 SUPERFAMILY SSF50677 200 371 1.31E-56 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MCR_0517 a37a513820891435434515908ccc5813 975 SUPERFAMILY SSF52374 7 654 2.56E-135 T 14-10-2018 MCR_0517 a37a513820891435434515908ccc5813 975 Gene3D G3DSA:1.10.730.10 596 841 1.5E-68 T 14-10-2018 MCR_0517 a37a513820891435434515908ccc5813 975 Gene3D G3DSA:3.90.740.10 250 321 3.0E-8 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MCR_0517 a37a513820891435434515908ccc5813 975 Hamap MF_02004 Valine--tRNA ligase [valS]. 6 973 15.873 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MCR_0517 a37a513820891435434515908ccc5813 975 SUPERFAMILY SSF46589 908 972 2.25E-14 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MCR_0517 a37a513820891435434515908ccc5813 975 Gene3D G3DSA:1.10.287.380 901 973 5.4E-19 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MCR_0517 a37a513820891435434515908ccc5813 975 Gene3D G3DSA:3.40.50.620 343 568 1.0E-68 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0517 a37a513820891435434515908ccc5813 975 Pfam PF08264 Anticodon-binding domain of tRNA 693 848 7.8E-40 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MCR_0517 a37a513820891435434515908ccc5813 975 Gene3D G3DSA:3.40.50.620 7 219 1.3E-67 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0517 a37a513820891435434515908ccc5813 975 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 908 972 1.8E-17 T 14-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 MCR_0517 a37a513820891435434515908ccc5813 975 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 51 62 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0517 a37a513820891435434515908ccc5813 975 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 644 2.2E-211 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MCR_0658 bec35b976ade04c98fd21a83aeee0d44 265 SUPERFAMILY SSF56300 18 239 8.54E-19 T 14-10-2018 MCR_0658 bec35b976ade04c98fd21a83aeee0d44 265 Pfam PF00149 Calcineurin-like phosphoesterase 18 222 5.8E-6 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MCR_0658 bec35b976ade04c98fd21a83aeee0d44 265 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 18 245 6.8E-58 T 14-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 MCR_0658 bec35b976ade04c98fd21a83aeee0d44 265 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 265 68.11 T 14-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 MCR_0372 47a9baa8075c71c7540bdd3c850b3885 171 Pfam PF01475 Ferric uptake regulator family 33 160 1.9E-9 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MCR_0372 47a9baa8075c71c7540bdd3c850b3885 171 SUPERFAMILY SSF46785 26 166 2.64E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0372 47a9baa8075c71c7540bdd3c850b3885 171 Gene3D G3DSA:3.30.1490.190 112 170 5.6E-13 T 14-10-2018 MCR_0372 47a9baa8075c71c7540bdd3c850b3885 171 Gene3D G3DSA:1.10.10.10 16 111 1.9E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_1674 51b4f3000eb850ff85813db1238d944d 228 Gene3D G3DSA:3.30.1330.60 36 220 4.7E-14 T 14-10-2018 IPR036737 OmpA-like domain superfamily MCR_1674 51b4f3000eb850ff85813db1238d944d 228 SUPERFAMILY SSF103088 81 209 8.37E-10 T 14-10-2018 IPR036737 OmpA-like domain superfamily MCR_1674 51b4f3000eb850ff85813db1238d944d 228 Pfam PF00691 OmpA family 87 171 1.5E-7 T 14-10-2018 IPR006665 OmpA-like domain MCR_1529 f5d69889b1a3a908b2e97fc2a54afb30 313 SUPERFAMILY SSF51735 97 284 4.04E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1529 f5d69889b1a3a908b2e97fc2a54afb30 313 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MCR_1529 f5d69889b1a3a908b2e97fc2a54afb30 313 Gene3D G3DSA:3.40.50.720 18 307 3.2E-99 T 14-10-2018 MCR_1529 f5d69889b1a3a908b2e97fc2a54afb30 313 SUPERFAMILY SSF52283 22 118 8.32E-26 T 14-10-2018 MCR_1529 f5d69889b1a3a908b2e97fc2a54afb30 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 25 312 2.7E-21 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MCR_1529 f5d69889b1a3a908b2e97fc2a54afb30 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 283 1.9E-51 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MCR_1529 f5d69889b1a3a908b2e97fc2a54afb30 313 Gene3D G3DSA:3.40.50.720 93 282 3.2E-99 T 14-10-2018 MCR_0122 db80d59a970906865c93d5760c199cc5 494 Gene3D G3DSA:3.40.50.300 381 485 2.1E-9 T 14-10-2018 MCR_0122 db80d59a970906865c93d5760c199cc5 494 Pfam PF13361 UvrD-like helicase C-terminal domain 423 476 1.5E-7 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MCR_0122 db80d59a970906865c93d5760c199cc5 494 Pfam PF13245 AAA domain 15 251 4.9E-9 T 14-10-2018 MCR_0122 db80d59a970906865c93d5760c199cc5 494 SUPERFAMILY SSF52540 8 480 3.3E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0890 fa3c92ede13131c3c0223a4d6fce8e06 119 Pfam PF02152 Dihydroneopterin aldolase 5 113 7.0E-31 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MCR_0890 fa3c92ede13131c3c0223a4d6fce8e06 119 TIGRFAM TIGR00526 folB_dom: FolB domain 3 117 2.1E-30 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MCR_0890 fa3c92ede13131c3c0223a4d6fce8e06 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 5 114 4.0E-27 T 14-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MCR_0890 fa3c92ede13131c3c0223a4d6fce8e06 119 Gene3D G3DSA:3.30.1130.10 1 118 2.0E-35 T 14-10-2018 MCR_0890 fa3c92ede13131c3c0223a4d6fce8e06 119 SUPERFAMILY SSF55620 2 115 4.73E-32 T 14-10-2018 MCR_0890 fa3c92ede13131c3c0223a4d6fce8e06 119 SMART SM00905 5 115 1.1E-38 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MCR_0373 cc91860acd1c4b6cdadcac93383b5be0 296 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 292 1.5E-25 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MCR_0373 cc91860acd1c4b6cdadcac93383b5be0 296 Gene3D G3DSA:3.40.50.1980 192 293 2.1E-6 T 14-10-2018 MCR_0373 cc91860acd1c4b6cdadcac93383b5be0 296 SUPERFAMILY SSF53807 40 292 1.47E-36 T 14-10-2018 MCR_0373 cc91860acd1c4b6cdadcac93383b5be0 296 Gene3D G3DSA:3.40.50.1980 39 191 2.9E-25 T 14-10-2018 MCR_0057 6c635949ec80c573ebf2d338b54507df 298 Gene3D G3DSA:3.30.2350.10 79 291 7.8E-45 T 14-10-2018 MCR_0057 6c635949ec80c573ebf2d338b54507df 298 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 131 145 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0057 6c635949ec80c573ebf2d338b54507df 298 SUPERFAMILY SSF55120 77 292 3.68E-50 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_0057 6c635949ec80c573ebf2d338b54507df 298 Pfam PF00849 RNA pseudouridylate synthase 93 240 7.3E-24 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MCR_1465 9065f9c5bcb232efef4d7502eac37607 532 Pfam PF03806 AbgT putative transporter family 20 529 9.3E-218 T 14-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 MCR_1460 8d49377c5efa0c67bcfd191d26868aaf 269 SMART SM00900 153 249 1.0E-26 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MCR_1460 8d49377c5efa0c67bcfd191d26868aaf 269 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 5 256 1.1E-69 T 14-10-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0010181|GO:0016021|GO:0016655 MCR_1460 8d49377c5efa0c67bcfd191d26868aaf 269 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 5 263 31.663 T 14-10-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0010181|GO:0016021|GO:0016655 MCR_1460 8d49377c5efa0c67bcfd191d26868aaf 269 PIRSF PIRSF009437 1 264 7.6E-78 T 14-10-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0010181|GO:0016021|GO:0016655 MCR_1460 8d49377c5efa0c67bcfd191d26868aaf 269 Pfam PF04205 FMN-binding domain 153 246 8.6E-18 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MCR_1647 88bfdd178914060fd4d6dd6857cb995b 253 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 47 245 2.6E-15 T 14-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MCR_1647 88bfdd178914060fd4d6dd6857cb995b 253 Pfam PF04973 Nicotinamide mononucleotide transporter 47 243 2.5E-36 T 14-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MCR_0012 a1422de4b6e1b30bac3e71cc2c708fc6 296 Gene3D G3DSA:3.40.640.10 1 296 1.5E-105 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_0012 a1422de4b6e1b30bac3e71cc2c708fc6 296 Pfam PF00155 Aminotransferase class I and II 42 285 1.9E-19 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MCR_0012 a1422de4b6e1b30bac3e71cc2c708fc6 296 SUPERFAMILY SSF53383 42 293 1.33E-39 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0841 e7e3b5d8e04e1d526ac60a33cf178c96 140 Gene3D G3DSA:2.40.50.100 61 137 2.9E-26 T 14-10-2018 MCR_0841 e7e3b5d8e04e1d526ac60a33cf178c96 140 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 85 99 5.1E-14 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MCR_0841 e7e3b5d8e04e1d526ac60a33cf178c96 140 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 68 81 5.1E-14 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MCR_0841 e7e3b5d8e04e1d526ac60a33cf178c96 140 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 100 113 5.1E-14 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MCR_0841 e7e3b5d8e04e1d526ac60a33cf178c96 140 SUPERFAMILY SSF51230 67 136 1.05E-20 T 14-10-2018 IPR011053 Single hybrid motif MCR_0841 e7e3b5d8e04e1d526ac60a33cf178c96 140 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 137 2.0E-36 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MCR_0841 e7e3b5d8e04e1d526ac60a33cf178c96 140 Pfam PF00364 Biotin-requiring enzyme 67 136 1.6E-18 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MCR_1498 bd0ed5a54368f85fe7a9a51c6c380dc4 500 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 18 276 8.7E-61 T 14-10-2018 IPR017039 Virulence factor BrkB MCR_1498 bd0ed5a54368f85fe7a9a51c6c380dc4 500 Pfam PF03631 Virulence factor BrkB 28 275 3.9E-58 T 14-10-2018 IPR017039 Virulence factor BrkB MCR_1498 bd0ed5a54368f85fe7a9a51c6c380dc4 500 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 1 301 20.251 T 14-10-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial MCR_1291 520fd5e2ed348cebff0e6061e1f1f7c1 410 SUPERFAMILY SSF51713 28 401 7.46E-157 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MCR_1291 520fd5e2ed348cebff0e6061e1f1f7c1 410 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 40 404 3.3E-169 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MCR_1291 520fd5e2ed348cebff0e6061e1f1f7c1 410 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 40 403 5.6E-161 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MCR_1291 520fd5e2ed348cebff0e6061e1f1f7c1 410 Pfam PF01702 Queuine tRNA-ribosyltransferase 158 397 4.8E-93 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MCR_1291 520fd5e2ed348cebff0e6061e1f1f7c1 410 Gene3D G3DSA:3.20.20.105 21 404 5.1E-169 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MCR_1291 520fd5e2ed348cebff0e6061e1f1f7c1 410 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 29 400 55.757 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MCR_0161 402cbc0a3fd0e4c3d68b5dbdeab34601 400 SUPERFAMILY SSF53383 6 395 1.24E-80 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0161 402cbc0a3fd0e4c3d68b5dbdeab34601 400 Pfam PF00155 Aminotransferase class I and II 43 385 2.4E-44 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MCR_0161 402cbc0a3fd0e4c3d68b5dbdeab34601 400 Gene3D G3DSA:3.40.640.10 60 298 2.6E-105 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_0161 402cbc0a3fd0e4c3d68b5dbdeab34601 400 Gene3D G3DSA:3.90.1150.10 46 382 2.6E-105 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_1860 80c8bc912136004c4d1bb2e6f92662b1 119 Gene3D G3DSA:2.40.50.1010 9 76 3.5E-5 T 14-10-2018 MCR_0176 9a2665f8a225fbe374516fa788744963 276 Gene3D G3DSA:3.40.190.10 40 269 1.1E-86 T 14-10-2018 MCR_0176 9a2665f8a225fbe374516fa788744963 276 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 12 276 1.8E-124 T 14-10-2018 IPR004872 Lipoprotein NlpA family MCR_0176 9a2665f8a225fbe374516fa788744963 276 Pfam PF03180 NLPA lipoprotein 39 276 8.0E-95 T 14-10-2018 IPR004872 Lipoprotein NlpA family MCR_0176 9a2665f8a225fbe374516fa788744963 276 PIRSF PIRSF002854 1 276 1.3E-96 T 14-10-2018 IPR004872 Lipoprotein NlpA family MCR_0176 9a2665f8a225fbe374516fa788744963 276 Gene3D G3DSA:3.40.190.10 122 226 1.1E-86 T 14-10-2018 MCR_0176 9a2665f8a225fbe374516fa788744963 276 SUPERFAMILY SSF53850 38 276 2.81E-76 T 14-10-2018 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 Pfam PF14824 Sirohaem biosynthesis protein central 123 148 2.1E-8 T 14-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 Gene3D G3DSA:1.10.8.210 151 207 1.9E-8 T 14-10-2018 IPR037115 Sirohaem synthase, dimerisation domain superfamily GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 Gene3D G3DSA:3.30.950.10 328 449 1.7E-38 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 Gene3D G3DSA:3.40.1010.10 211 327 6.6E-44 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 Gene3D G3DSA:3.40.50.720 1 114 1.3E-28 T 14-10-2018 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 SUPERFAMILY SSF51735 1 115 1.67E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 Gene3D G3DSA:3.30.160.110 115 150 4.0E-17 T 14-10-2018 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 PIRSF PIRSF036426 1 449 1.7E-166 T 14-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 191 3.9E-65 T 14-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 Pfam PF10414 Sirohaem synthase dimerisation region 152 189 1.4E-11 T 14-10-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 SUPERFAMILY SSF75615 116 193 1.96E-24 T 14-10-2018 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 212 446 1.4E-89 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 214 423 8.0E-50 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 Pfam PF13241 Putative NAD(P)-binding 6 117 8.1E-25 T 14-10-2018 MCR_1132 ec95e0f671ddb8b545156ccbfca67bf1 449 SUPERFAMILY SSF53790 207 447 6.54E-73 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MCR_0038 fcc51cd903ebf6f68e56605b0ab05798 286 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0038 fcc51cd903ebf6f68e56605b0ab05798 286 Pfam PF00005 ABC transporter 28 168 1.8E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_0038 fcc51cd903ebf6f68e56605b0ab05798 286 SMART SM00382 36 218 3.1E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0038 fcc51cd903ebf6f68e56605b0ab05798 286 Gene3D G3DSA:3.40.50.300 8 273 2.6E-60 T 14-10-2018 MCR_0038 fcc51cd903ebf6f68e56605b0ab05798 286 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 28 256 6.2E-88 T 14-10-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 MCR_0038 fcc51cd903ebf6f68e56605b0ab05798 286 SUPERFAMILY SSF52540 10 236 4.09E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1548 accdce74723c0f4d93dad6c3110de948 611 Gene3D G3DSA:3.40.50.970 402 610 5.4E-65 T 14-10-2018 MCR_1548 accdce74723c0f4d93dad6c3110de948 611 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 231 365 1.6E-45 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MCR_1548 accdce74723c0f4d93dad6c3110de948 611 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 39 201 2.6E-58 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MCR_1548 accdce74723c0f4d93dad6c3110de948 611 SUPERFAMILY SSF52518 409 606 2.16E-68 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MCR_1548 accdce74723c0f4d93dad6c3110de948 611 Gene3D G3DSA:3.40.50.1220 225 396 2.1E-63 T 14-10-2018 MCR_1548 accdce74723c0f4d93dad6c3110de948 611 SUPERFAMILY SSF52518 37 204 1.18E-64 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MCR_1548 accdce74723c0f4d93dad6c3110de948 611 SUPERFAMILY SSF52467 224 397 4.81E-67 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MCR_1548 accdce74723c0f4d93dad6c3110de948 611 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 39 606 2.4E-260 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MCR_1548 accdce74723c0f4d93dad6c3110de948 611 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 434 582 1.2E-49 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MCR_1548 accdce74723c0f4d93dad6c3110de948 611 Gene3D G3DSA:3.40.50.970 32 214 4.3E-73 T 14-10-2018 MCR_0912 45eec8887e27b1e891d1e5339fe2702c 191 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 5 173 2.4E-27 T 14-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 MCR_0912 45eec8887e27b1e891d1e5339fe2702c 191 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 11 173 6.3E-20 T 14-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related MCR_0422 c6a4f23e876b01c94370813cd32d6ea2 371 SUPERFAMILY SSF56784 156 364 2.8E-53 T 14-10-2018 IPR036412 HAD-like superfamily MCR_0422 c6a4f23e876b01c94370813cd32d6ea2 371 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 145 361 7.0E-65 T 14-10-2018 MCR_0422 c6a4f23e876b01c94370813cd32d6ea2 371 Pfam PF12710 haloacid dehalogenase-like hydrolase 160 328 1.7E-21 T 14-10-2018 MCR_0422 c6a4f23e876b01c94370813cd32d6ea2 371 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 159 329 1.6E-35 T 14-10-2018 MCR_0422 c6a4f23e876b01c94370813cd32d6ea2 371 Gene3D G3DSA:3.40.50.1000 85 366 9.4E-74 T 14-10-2018 IPR023214 HAD superfamily MCR_0205 3e04db7f6f278da9fa9fa84868510541 375 Pfam PF00266 Aminotransferase class-V 22 332 2.4E-13 T 14-10-2018 IPR000192 Aminotransferase class V domain MCR_0205 3e04db7f6f278da9fa9fa84868510541 375 Gene3D G3DSA:3.40.640.10 39 269 9.6E-110 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_0205 3e04db7f6f278da9fa9fa84868510541 375 SUPERFAMILY SSF53383 10 371 4.59E-65 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0205 3e04db7f6f278da9fa9fa84868510541 375 Gene3D G3DSA:3.90.1150.10 270 368 9.6E-110 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_0205 3e04db7f6f278da9fa9fa84868510541 375 PIRSF PIRSF000524 17 375 4.4E-41 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 MCR_0168 b69c03d58c141514acfae61c1e8c78c2 219 Gene3D G3DSA:3.40.50.620 3 214 1.0E-49 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0168 b69c03d58c141514acfae61c1e8c78c2 219 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 212 4.7E-38 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MCR_0168 b69c03d58c141514acfae61c1e8c78c2 219 SUPERFAMILY SSF52374 3 215 8.76E-36 T 14-10-2018 MCR_0168 b69c03d58c141514acfae61c1e8c78c2 219 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 213 23.705 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MCR_0168 b69c03d58c141514acfae61c1e8c78c2 219 Pfam PF01467 Cytidylyltransferase-like 5 184 1.8E-20 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MCR_1560 adc5e9e766b31e2d1eb5ca9966613166 96 ProSitePatterns PS01167 Ribosomal protein L17 signature. 11 33 - T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1560 adc5e9e766b31e2d1eb5ca9966613166 96 TIGRFAM TIGR00059 L17: ribosomal protein bL17 1 94 7.7E-39 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1560 adc5e9e766b31e2d1eb5ca9966613166 96 Gene3D G3DSA:3.90.1030.10 1 92 3.8E-37 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1560 adc5e9e766b31e2d1eb5ca9966613166 96 Pfam PF01196 Ribosomal protein L17 1 93 8.1E-33 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1560 adc5e9e766b31e2d1eb5ca9966613166 96 SUPERFAMILY SSF64263 1 96 4.58E-41 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0126 2a9959ff5db5d22f355f3f6a929a78bd 178 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 2.9E-14 T 14-10-2018 MCR_0126 2a9959ff5db5d22f355f3f6a929a78bd 178 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 2.9E-14 T 14-10-2018 MCR_0126 2a9959ff5db5d22f355f3f6a929a78bd 178 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 2.9E-14 T 14-10-2018 MCR_0126 2a9959ff5db5d22f355f3f6a929a78bd 178 Pfam PF02416 mttA/Hcf106 family 5 61 1.7E-8 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MCR_1218 e662b202e8386e208f0b4674fe2a575c 37 Gene3D G3DSA:3.40.50.720 2 24 5.4E-7 T 14-10-2018 MCR_1766 a25c49f08bf5201cb815e0f4e4939171 168 Pfam PF09557 Domain of unknown function (DUF2382) 13 151 6.2E-17 T 14-10-2018 IPR019060 Domain of unknown function DUF2382 MCR_0378 4b2de0f31bb4b67a900c8313a69c5de3 155 SUPERFAMILY SSF81573 63 120 2.75E-12 T 14-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily MCR_0378 4b2de0f31bb4b67a900c8313a69c5de3 155 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 137 12.456 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MCR_0378 4b2de0f31bb4b67a900c8313a69c5de3 155 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 9 155 8.9E-44 T 14-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 MCR_0378 4b2de0f31bb4b67a900c8313a69c5de3 155 Pfam PF00430 ATP synthase B/B' CF(0) 5 136 9.5E-32 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MCR_0378 4b2de0f31bb4b67a900c8313a69c5de3 155 Gene3D G3DSA:1.20.5.620 62 121 1.8E-13 T 14-10-2018 MCR_1337 ad5dbf6df3c1de18449f7e94bf7e6291 304 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 18 293 3.2E-85 T 14-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 MCR_1337 ad5dbf6df3c1de18449f7e94bf7e6291 304 Pfam PF01040 UbiA prenyltransferase family 35 281 1.2E-54 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MCR_1337 ad5dbf6df3c1de18449f7e94bf7e6291 304 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 11 301 25.797 T 14-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 MCR_1337 ad5dbf6df3c1de18449f7e94bf7e6291 304 Gene3D G3DSA:1.10.357.140 31 192 1.6E-37 T 14-10-2018 MCR_1825 df21bd399cb6758f2f812cc720ce1283 270 Pfam PF13489 Methyltransferase domain 75 226 3.1E-20 T 14-10-2018 MCR_1825 df21bd399cb6758f2f812cc720ce1283 270 Gene3D G3DSA:3.40.50.150 29 259 8.7E-71 T 14-10-2018 MCR_1825 df21bd399cb6758f2f812cc720ce1283 270 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 29 260 35.387 T 14-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MCR_1825 df21bd399cb6758f2f812cc720ce1283 270 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 29 254 3.9E-83 T 14-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MCR_1825 df21bd399cb6758f2f812cc720ce1283 270 SUPERFAMILY SSF53335 31 260 1.28E-45 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0559 9ac3bea471a169d6e5ecc470e600e918 207 Gene3D G3DSA:1.20.1440.20 19 197 2.5E-59 T 14-10-2018 IPR023353 LemA-like domain superfamily MCR_0559 9ac3bea471a169d6e5ecc470e600e918 207 Pfam PF04011 LemA family 9 197 9.3E-63 T 14-10-2018 IPR007156 LemA MCR_0559 9ac3bea471a169d6e5ecc470e600e918 207 SUPERFAMILY SSF140478 27 184 1.2E-51 T 14-10-2018 IPR023353 LemA-like domain superfamily MCR_1485 4a17442098db9353b244bada4a1d3310 299 SUPERFAMILY SSF54506 3 276 2.17E-49 T 14-10-2018 MCR_1485 4a17442098db9353b244bada4a1d3310 299 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 280 38.143 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MCR_1485 4a17442098db9353b244bada4a1d3310 299 Gene3D G3DSA:3.10.310.10 117 267 1.7E-94 T 14-10-2018 MCR_1485 4a17442098db9353b244bada4a1d3310 299 Pfam PF01678 Diaminopimelate epimerase 5 125 1.4E-30 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MCR_1485 4a17442098db9353b244bada4a1d3310 299 Pfam PF01678 Diaminopimelate epimerase 157 272 7.8E-27 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MCR_1485 4a17442098db9353b244bada4a1d3310 299 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 14-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MCR_1485 4a17442098db9353b244bada4a1d3310 299 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 3 277 2.4E-90 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MCR_1485 4a17442098db9353b244bada4a1d3310 299 Gene3D G3DSA:3.10.310.10 4 276 1.7E-94 T 14-10-2018 MCR_0376 a686b94fdb39ed646a6e9c6fbd2ec711 289 SUPERFAMILY SSF81336 101 281 4.84E-42 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0376 a686b94fdb39ed646a6e9c6fbd2ec711 289 Gene3D G3DSA:1.20.120.220 99 289 4.7E-56 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0376 a686b94fdb39ed646a6e9c6fbd2ec711 289 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 44 281 3.4E-40 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0376 a686b94fdb39ed646a6e9c6fbd2ec711 289 Hamap MF_01393 ATP synthase subunit a [atpB]. 11 287 15.469 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0376 a686b94fdb39ed646a6e9c6fbd2ec711 289 Pfam PF00119 ATP synthase A chain 50 281 8.3E-57 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0376 a686b94fdb39ed646a6e9c6fbd2ec711 289 ProSitePatterns PS00449 ATP synthase a subunit signature. 223 232 - T 14-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MCR_0256 81c5fd3202b0d6586d983d824f52bdd3 124 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 58 124 1.9E-32 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0256 81c5fd3202b0d6586d983d824f52bdd3 124 SUPERFAMILY SSF48300 4 60 3.4E-15 T 14-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0256 81c5fd3202b0d6586d983d824f52bdd3 124 Gene3D G3DSA:1.20.5.710 2 53 8.8E-22 T 14-10-2018 MCR_0256 81c5fd3202b0d6586d983d824f52bdd3 124 Gene3D G3DSA:3.30.1390.10 54 124 1.5E-31 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MCR_0256 81c5fd3202b0d6586d983d824f52bdd3 124 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 52 5.6E-16 T 14-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0256 81c5fd3202b0d6586d983d824f52bdd3 124 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 59 98 1.0E-11 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0256 81c5fd3202b0d6586d983d824f52bdd3 124 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 124 25.491 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0256 81c5fd3202b0d6586d983d824f52bdd3 124 SUPERFAMILY SSF54736 53 124 2.27E-25 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MCR_0256 81c5fd3202b0d6586d983d824f52bdd3 124 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 124 6.0E-49 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0826 9d7f229200585606d77bbe70f506f12a 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 66 2.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MCR_0826 9d7f229200585606d77bbe70f506f12a 238 Gene3D G3DSA:1.10.10.60 6 57 1.6E-22 T 14-10-2018 MCR_0826 9d7f229200585606d77bbe70f506f12a 238 SUPERFAMILY SSF46689 9 82 3.69E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MCR_0826 9d7f229200585606d77bbe70f506f12a 238 Gene3D G3DSA:1.10.357.10 58 237 4.5E-36 T 14-10-2018 MCR_1115 dab6bc2b134e7d5fa40595c95f2fac8e 434 Gene3D G3DSA:1.10.4030.30 32 287 6.9E-42 T 14-10-2018 MCR_1115 dab6bc2b134e7d5fa40595c95f2fac8e 434 Gene3D G3DSA:3.10.50.40 289 427 2.4E-39 T 14-10-2018 MCR_1115 dab6bc2b134e7d5fa40595c95f2fac8e 434 Pfam PF13616 PPIC-type PPIASE domain 292 390 1.4E-26 T 14-10-2018 MCR_1115 dab6bc2b134e7d5fa40595c95f2fac8e 434 Pfam PF00639 PPIC-type PPIASE domain 185 280 6.7E-6 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 MCR_1115 dab6bc2b134e7d5fa40595c95f2fac8e 434 SUPERFAMILY SSF54534 292 391 1.44E-28 T 14-10-2018 MCR_1115 dab6bc2b134e7d5fa40595c95f2fac8e 434 SUPERFAMILY SSF109998 32 203 9.42E-24 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily MCR_1115 dab6bc2b134e7d5fa40595c95f2fac8e 434 Gene3D G3DSA:3.10.50.40 179 283 6.9E-42 T 14-10-2018 MCR_1115 dab6bc2b134e7d5fa40595c95f2fac8e 434 SUPERFAMILY SSF54534 180 284 1.31E-10 T 14-10-2018 MCR_1115 dab6bc2b134e7d5fa40595c95f2fac8e 434 Pfam PF09312 SurA N-terminal domain 32 145 5.4E-12 T 14-10-2018 IPR015391 SurA N-terminal MCR_0454 8262da925818bc85ac1bd5a20c50225b 389 PIRSF PIRSF000813 260 382 2.2E-5 T 14-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 MCR_0454 8262da925818bc85ac1bd5a20c50225b 389 PIRSF PIRSF000813 1 265 6.1E-96 T 14-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 MCR_0454 8262da925818bc85ac1bd5a20c50225b 389 SUPERFAMILY SSF81301 1 128 9.26E-26 T 14-10-2018 MCR_0454 8262da925818bc85ac1bd5a20c50225b 389 Gene3D G3DSA:1.10.3090.10 131 384 1.2E-34 T 14-10-2018 MCR_0454 8262da925818bc85ac1bd5a20c50225b 389 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 158 221 6.6E-9 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MCR_0454 8262da925818bc85ac1bd5a20c50225b 389 Gene3D G3DSA:3.30.460.10 1 130 4.3E-25 T 14-10-2018 MCR_0454 8262da925818bc85ac1bd5a20c50225b 389 Pfam PF01743 Poly A polymerase head domain 3 131 1.1E-17 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MCR_0454 8262da925818bc85ac1bd5a20c50225b 389 SUPERFAMILY SSF81891 129 380 6.54E-37 T 14-10-2018 MCR_0799 0900bf56e64f529058d19155d3ecd7fe 133 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 132 1.6E-28 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 MCR_0799 0900bf56e64f529058d19155d3ecd7fe 133 Gene3D G3DSA:3.30.420.270 62 130 7.1E-11 T 14-10-2018 MCR_1447 8cbda56eb5f0e9bb05e1a30a0117317f 81 Pfam PF10982 Protein of unknown function (DUF2789) 6 75 2.5E-28 T 14-10-2018 IPR021250 Protein of unknown function DUF2789 MCR_1447 8cbda56eb5f0e9bb05e1a30a0117317f 81 Gene3D G3DSA:1.10.10.1130 2 80 4.2E-28 T 14-10-2018 MCR_1393 0a533c9611108f794f34e5bcd84e295d 153 SUPERFAMILY SSF141488 58 145 1.19E-11 T 14-10-2018 IPR036328 C-type lysozyme inhibitor superfamily MCR_1393 0a533c9611108f794f34e5bcd84e295d 153 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 61 135 2.6E-12 T 14-10-2018 IPR018660 C-type lysozyme inhibitor MCR_1393 0a533c9611108f794f34e5bcd84e295d 153 Gene3D G3DSA:2.40.128.200 55 150 1.7E-15 T 14-10-2018 IPR036328 C-type lysozyme inhibitor superfamily MCR_1556 f03d5144b30d5580bcaaf5406a03f3e2 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.404 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1556 f03d5144b30d5580bcaaf5406a03f3e2 60 Pfam PF01783 Ribosomal L32p protein family 2 55 1.7E-19 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1556 f03d5144b30d5580bcaaf5406a03f3e2 60 SUPERFAMILY SSF57829 2 55 1.46E-17 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MCR_1556 f03d5144b30d5580bcaaf5406a03f3e2 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 8.9E-20 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_0738 471f63946f546ac7a90e870affec7195 149 Pfam PF01144 Coenzyme A transferase 29 139 6.4E-19 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MCR_0738 471f63946f546ac7a90e870affec7195 149 SUPERFAMILY SSF100950 17 147 1.68E-37 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MCR_0738 471f63946f546ac7a90e870affec7195 149 SMART SM00882 1 141 2.8E-5 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MCR_0738 471f63946f546ac7a90e870affec7195 149 Gene3D G3DSA:3.40.1080.10 8 148 1.1E-53 T 14-10-2018 MCR_0030 7456a1c30a6c1aa536d5f90aefdb7226 196 Pfam PF09618 CRISPR-associated protein (Cas_Csy4) 4 196 1.9E-57 T 14-10-2018 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 MCR_0030 7456a1c30a6c1aa536d5f90aefdb7226 196 TIGRFAM TIGR02563 cas_Csy4: CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST 3 196 5.2E-38 T 14-10-2018 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 MCR_0030 7456a1c30a6c1aa536d5f90aefdb7226 196 Gene3D G3DSA:3.30.70.2540 1 196 5.7E-61 T 14-10-2018 MCR_0548 dfd8e5dcf2101c017e5fdaf9bb2296ce 175 SUPERFAMILY SSF54637 27 167 3.51E-44 T 14-10-2018 IPR029069 HotDog domain superfamily MCR_0548 dfd8e5dcf2101c017e5fdaf9bb2296ce 175 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 30 167 6.2E-54 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MCR_0548 dfd8e5dcf2101c017e5fdaf9bb2296ce 175 Gene3D G3DSA:3.10.129.10 21 171 8.6E-56 T 14-10-2018 MCR_0548 dfd8e5dcf2101c017e5fdaf9bb2296ce 175 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 28 170 30.767 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MCR_0548 dfd8e5dcf2101c017e5fdaf9bb2296ce 175 Pfam PF07977 FabA-like domain 37 162 8.1E-31 T 14-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MCR_0084 0f88b50600de8748f5f32cfdc544e5fe 707 SUPERFAMILY SSF55486 11 703 2.47E-163 T 14-10-2018 MCR_0084 0f88b50600de8748f5f32cfdc544e5fe 707 Pfam PF01432 Peptidase family M3 243 702 4.1E-131 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MCR_0084 0f88b50600de8748f5f32cfdc544e5fe 707 Gene3D G3DSA:1.10.1370.40 20 701 8.5E-219 T 14-10-2018 MCR_0084 0f88b50600de8748f5f32cfdc544e5fe 707 Gene3D G3DSA:1.10.1370.10 153 635 8.5E-219 T 14-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 MCR_1880 cf961abc7b4463f4362e2155420efa95 153 Gene3D G3DSA:1.20.120.520 10 148 2.3E-11 T 14-10-2018 MCR_1880 cf961abc7b4463f4362e2155420efa95 153 Pfam PF01814 Hemerythrin HHE cation binding domain 30 129 1.8E-8 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MCR_0046 b4c27d198a10aaf224d9671a9f1483fc 326 SUPERFAMILY SSF53474 65 276 8.55E-27 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0046 b4c27d198a10aaf224d9671a9f1483fc 326 Gene3D G3DSA:3.40.50.1820 63 283 6.4E-19 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0046 b4c27d198a10aaf224d9671a9f1483fc 326 ProSitePatterns PS01133 Uncharacterized protein family UPF0017 signature. 230 271 - T 14-10-2018 IPR000952 AB hydrolase 4, conserved site MCR_0046 b4c27d198a10aaf224d9671a9f1483fc 326 PIRSF PIRSF005211 2 325 8.0E-85 T 14-10-2018 IPR012020 AB hydrolase 4 family MCR_1258 2290a3c950536f33e6cd8431a7f324f4 125 Pfam PF03788 LrgA family 14 103 7.9E-23 T 14-10-2018 IPR005538 LrgA/CidA family GO:0016021 MCR_1253 2aec06074f095a208de05c927035ed27 180 SUPERFAMILY SSF51283 3 179 3.01E-49 T 14-10-2018 IPR036157 dUTPase-like superfamily MCR_1253 2aec06074f095a208de05c927035ed27 180 Gene3D G3DSA:2.70.40.10 1 150 1.7E-50 T 14-10-2018 IPR036157 dUTPase-like superfamily MCR_1253 2aec06074f095a208de05c927035ed27 180 Pfam PF00692 dUTPase 70 174 2.0E-8 T 14-10-2018 IPR029054 dUTPase-like MCR_1253 2aec06074f095a208de05c927035ed27 180 Hamap MF_00146 dCTP deaminase [dcd]. 1 180 25.721 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 MCR_1253 2aec06074f095a208de05c927035ed27 180 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 7 179 1.2E-45 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 MCR_1608 cd4c9740ec17045f4874113e5918219f 265 Pfam PF08543 Phosphomethylpyrimidine kinase 17 252 4.2E-62 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MCR_1608 cd4c9740ec17045f4874113e5918219f 265 SUPERFAMILY SSF53613 6 251 1.64E-57 T 14-10-2018 IPR029056 Ribokinase-like MCR_1608 cd4c9740ec17045f4874113e5918219f 265 Gene3D G3DSA:3.40.1190.20 1 244 7.9E-69 T 14-10-2018 IPR029056 Ribokinase-like MCR_1751 6bc74aa68628826608b4d8007c3b95ca 137 Gene3D G3DSA:3.40.1350.10 18 137 1.6E-24 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 MCR_1751 6bc74aa68628826608b4d8007c3b95ca 137 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 11 137 2.0E-22 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 MCR_1751 6bc74aa68628826608b4d8007c3b95ca 137 Hamap MF_00048 UPF0102 protein YraN [yraN]. 11 134 18.814 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 MCR_1751 6bc74aa68628826608b4d8007c3b95ca 137 Pfam PF02021 Uncharacterised protein family UPF0102 19 119 2.9E-22 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 MCR_1751 6bc74aa68628826608b4d8007c3b95ca 137 SUPERFAMILY SSF52980 12 122 8.45E-15 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MCR_0028 acafb7e8d9e09d120f4dd59c15cf3de0 297 Pfam PF09614 CRISPR-associated protein (Cas_Csy2) 3 290 9.6E-92 T 14-10-2018 IPR013398 CRISPR-associated protein Csy2 MCR_0028 acafb7e8d9e09d120f4dd59c15cf3de0 297 TIGRFAM TIGR02565 cas_Csy2: CRISPR type I-F/YPEST-associated protein Csy2 4 291 2.0E-87 T 14-10-2018 IPR013398 CRISPR-associated protein Csy2 MCR_1502 1dd36bc614a9e092b493a049b2554238 692 Pfam PF13148 Protein of unknown function (DUF3987) 273 605 1.6E-44 T 14-10-2018 IPR025048 Protein of unknown function DUF3987) MCR_0747 0559bc23125db9704123e3fa2e53e9dd 512 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 435 3.8E-29 T 14-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 MCR_0747 0559bc23125db9704123e3fa2e53e9dd 512 SUPERFAMILY SSF54862 1 497 1.15E-176 T 14-10-2018 MCR_0747 0559bc23125db9704123e3fa2e53e9dd 512 Pfam PF13247 4Fe-4S dicluster domain 175 271 5.9E-38 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MCR_0747 0559bc23125db9704123e3fa2e53e9dd 512 Gene3D G3DSA:3.30.70.20 1 302 3.7E-103 T 14-10-2018 MCR_0747 0559bc23125db9704123e3fa2e53e9dd 512 Gene3D G3DSA:1.10.3650.10 358 434 6.1E-29 T 14-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 MCR_0747 0559bc23125db9704123e3fa2e53e9dd 512 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 493 1.8E-303 T 14-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 MCR_1612 7306d8992e56b7c5405bea56f1995553 265 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 4 95 6.8E-44 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1612 7306d8992e56b7c5405bea56f1995553 265 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 262 38.588 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1612 7306d8992e56b7c5405bea56f1995553 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 144 153 3.9E-41 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1612 7306d8992e56b7c5405bea56f1995553 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 60 78 3.9E-41 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1612 7306d8992e56b7c5405bea56f1995553 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 35 46 3.9E-41 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1612 7306d8992e56b7c5405bea56f1995553 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 81 97 3.9E-41 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1612 7306d8992e56b7c5405bea56f1995553 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 100 113 3.9E-41 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1612 7306d8992e56b7c5405bea56f1995553 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 129 3.9E-41 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1612 7306d8992e56b7c5405bea56f1995553 265 Gene3D G3DSA:3.90.226.10 2 261 3.2E-94 T 14-10-2018 MCR_1612 7306d8992e56b7c5405bea56f1995553 265 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 4 260 9.0E-116 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MCR_1612 7306d8992e56b7c5405bea56f1995553 265 SUPERFAMILY SSF52096 5 259 8.81E-85 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MCR_1343 7e8abc490fc833567615a2d98d674afb 245 Pfam PF01578 Cytochrome C assembly protein 22 243 5.7E-21 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MCR_1790 b8704a21ca560045755ba1167505c6dd 193 SUPERFAMILY SSF101307 24 189 4.97E-35 T 14-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 MCR_1790 b8704a21ca560045755ba1167505c6dd 193 Pfam PF04608 Phosphatidylglycerophosphatase A 30 186 1.4E-41 T 14-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 MCR_1790 b8704a21ca560045755ba1167505c6dd 193 PIRSF PIRSF006162 18 193 1.1E-50 T 14-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MCR_0608 423ad2d4807b31f557dbaf32425646a0 407 PIRSF PIRSF005572 4 387 1.4E-129 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MCR_0608 423ad2d4807b31f557dbaf32425646a0 407 Pfam PF00266 Aminotransferase class-V 7 371 8.0E-84 T 14-10-2018 IPR000192 Aminotransferase class V domain MCR_0608 423ad2d4807b31f557dbaf32425646a0 407 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 3 398 51.72 T 14-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 MCR_0608 423ad2d4807b31f557dbaf32425646a0 407 Gene3D G3DSA:3.90.1150.10 7 379 3.4E-158 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_0608 423ad2d4807b31f557dbaf32425646a0 407 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 6 407 2.8E-213 T 14-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 MCR_0608 423ad2d4807b31f557dbaf32425646a0 407 SUPERFAMILY SSF53383 6 393 1.88E-107 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0608 423ad2d4807b31f557dbaf32425646a0 407 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 200 219 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MCR_0608 423ad2d4807b31f557dbaf32425646a0 407 Gene3D G3DSA:3.40.640.10 18 265 3.4E-158 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_0153 7fe0f0a50030ce77a4009928da2df5dd 257 SUPERFAMILY SSF53098 5 215 4.83E-30 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MCR_0153 7fe0f0a50030ce77a4009928da2df5dd 257 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 50 255 5.4E-57 T 14-10-2018 IPR019288 Predicted 3'-5' exonuclease, PolB-like MCR_0153 7fe0f0a50030ce77a4009928da2df5dd 257 Gene3D G3DSA:3.30.420.10 6 209 6.0E-19 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MCR_0267 cc8248eb7c31c90db8abed7f74246b3a 297 SUPERFAMILY SSF55681 13 208 1.02E-23 T 14-10-2018 MCR_0267 cc8248eb7c31c90db8abed7f74246b3a 297 Gene3D G3DSA:3.30.930.10 3 236 4.4E-25 T 14-10-2018 MCR_0267 cc8248eb7c31c90db8abed7f74246b3a 297 SUPERFAMILY SSF50037 249 293 8.7E-5 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal MCR_0267 cc8248eb7c31c90db8abed7f74246b3a 297 Gene3D G3DSA:2.30.30.100 247 293 1.1E-6 T 14-10-2018 MCR_0837 b80fde053a3b1ae35403e324dc2f019b 164 Gene3D G3DSA:3.40.50.1240 1 163 5.7E-26 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MCR_0837 b80fde053a3b1ae35403e324dc2f019b 164 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 63 1.4E-9 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MCR_0837 b80fde053a3b1ae35403e324dc2f019b 164 SUPERFAMILY SSF53254 1 136 2.36E-19 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MCR_1892 64b29f4369b622a5f3349e2d5236b9e8 204 Pfam PF01300 Telomere recombination 19 199 4.8E-29 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 MCR_1892 64b29f4369b622a5f3349e2d5236b9e8 204 SUPERFAMILY SSF55821 10 203 1.53E-35 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MCR_1892 64b29f4369b622a5f3349e2d5236b9e8 204 Gene3D G3DSA:3.90.870.10 7 204 4.1E-41 T 14-10-2018 MCR_1892 64b29f4369b622a5f3349e2d5236b9e8 204 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 10 204 30.574 T 14-10-2018 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 MCR_1286 e3dc67bcc5c0f9a39380fac26fc2133d 88 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 12 87 1.2E-29 T 14-10-2018 IPR019886 Sodium symporter small subunit, predicted MCR_1286 e3dc67bcc5c0f9a39380fac26fc2133d 88 Pfam PF13937 Domain of unknown function (DUF4212) 10 85 2.8E-30 T 14-10-2018 IPR019886 Sodium symporter small subunit, predicted MCR_1078 315ad1787493378edd516037c65cab73 274 PIRSF PIRSF000094 1 265 1.0E-103 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MCR_1078 315ad1787493378edd516037c65cab73 274 Gene3D G3DSA:3.40.50.720 1 269 6.1E-55 T 14-10-2018 MCR_1078 315ad1787493378edd516037c65cab73 274 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 257 6.6E-79 T 14-10-2018 MCR_1078 315ad1787493378edd516037c65cab73 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1078 315ad1787493378edd516037c65cab73 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 7.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1078 315ad1787493378edd516037c65cab73 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 7.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1078 315ad1787493378edd516037c65cab73 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 7.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1078 315ad1787493378edd516037c65cab73 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 7.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MCR_1078 315ad1787493378edd516037c65cab73 274 SUPERFAMILY SSF51735 4 258 1.54E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0904 a25be47aef29e86445b34042da66f17d 416 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 7 148 2.1E-35 T 14-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 MCR_0904 a25be47aef29e86445b34042da66f17d 416 Gene3D G3DSA:3.40.50.720 8 401 1.5E-131 T 14-10-2018 MCR_0904 a25be47aef29e86445b34042da66f17d 416 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 152 399 1.5E-24 T 14-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 MCR_0904 a25be47aef29e86445b34042da66f17d 416 Gene3D G3DSA:3.30.360.10 162 359 1.5E-131 T 14-10-2018 MCR_0904 a25be47aef29e86445b34042da66f17d 416 SUPERFAMILY SSF51735 5 164 1.43E-16 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Gene3D G3DSA:3.10.20.310 26 98 4.7E-15 T 14-10-2018 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Gene3D G3DSA:3.10.20.310 273 349 1.5E-16 T 14-10-2018 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Gene3D G3DSA:3.10.20.310 182 272 3.6E-17 T 14-10-2018 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 PIRSF PIRSF006076 1 813 2.8E-220 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Gene3D G3DSA:2.40.160.50 433 813 3.8E-103 T 14-10-2018 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 9 813 22.167 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Pfam PF01103 Surface antigen 454 813 6.9E-63 T 14-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 34 813 8.2E-227 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Gene3D G3DSA:3.10.20.310 354 431 4.8E-24 T 14-10-2018 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Pfam PF07244 Surface antigen variable number repeat 101 179 5.6E-8 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Pfam PF07244 Surface antigen variable number repeat 353 427 1.4E-14 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Pfam PF07244 Surface antigen variable number repeat 183 269 2.7E-11 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Pfam PF07244 Surface antigen variable number repeat 272 348 7.4E-9 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MCR_0546 fecf5a13a86c9d0a4991cdbbb89f1e04 813 Gene3D G3DSA:3.10.20.310 99 179 3.8E-14 T 14-10-2018 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 43 643 4.5E-206 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 201 227 3.9E-84 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 235 255 3.9E-84 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 70 96 3.9E-84 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 301 320 3.9E-84 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 285 301 3.9E-84 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 122 139 3.9E-84 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 150 172 3.9E-84 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 265 285 3.9E-84 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 306 640 1.9E-105 T 14-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 Pfam PF01578 Cytochrome C assembly protein 79 286 1.6E-51 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 103 126 8.6E-28 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 180 195 8.6E-28 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 633 646 8.6E-28 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 342 359 8.6E-28 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 304 319 8.6E-28 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1237 fdfdab470cc5de2a042a163d8c829c96 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 385 404 8.6E-28 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_1552 b528284c8aacb0278adb79b6b5b68f7a 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 7.3E-28 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MCR_1552 b528284c8aacb0278adb79b6b5b68f7a 78 Pfam PF00550 Phosphopantetheine attachment site 7 73 1.4E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain MCR_1552 b528284c8aacb0278adb79b6b5b68f7a 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 20.186 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MCR_1552 b528284c8aacb0278adb79b6b5b68f7a 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site MCR_1552 b528284c8aacb0278adb79b6b5b68f7a 78 SUPERFAMILY SSF47336 1 77 4.19E-23 T 14-10-2018 IPR036736 ACP-like superfamily MCR_1552 b528284c8aacb0278adb79b6b5b68f7a 78 Gene3D G3DSA:1.10.1200.10 1 76 1.4E-25 T 14-10-2018 IPR036736 ACP-like superfamily MCR_1552 b528284c8aacb0278adb79b6b5b68f7a 78 SMART SM00823 Phosphopantetheine attachment site 5 63 0.0085 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MCR_1552 b528284c8aacb0278adb79b6b5b68f7a 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 73 6.0E-11 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MCR_1458 ed3a5875fe944edf7c986001bddf215a 450 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 1 450 43.574 T 14-10-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MCR_1458 ed3a5875fe944edf7c986001bddf215a 450 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 2 450 9.7E-163 T 14-10-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MCR_1458 ed3a5875fe944edf7c986001bddf215a 450 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 1 260 5.8E-99 T 14-10-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MCR_1458 ed3a5875fe944edf7c986001bddf215a 450 Pfam PF11973 NQRA C-terminal domain 266 313 1.2E-20 T 14-10-2018 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 MCR_0782 f918cc8fecba465911a531f01c42b404 225 SUPERFAMILY SSF52317 1 223 2.37E-76 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_0782 f918cc8fecba465911a531f01c42b404 225 Pfam PF01965 DJ-1/PfpI family 25 221 2.4E-17 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MCR_0782 f918cc8fecba465911a531f01c42b404 225 Gene3D G3DSA:3.40.50.880 1 225 8.6E-84 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MCR_0177 b7e145fbabacce397c045e2cb23e18af 229 SUPERFAMILY SSF161098 18 213 8.76E-42 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0177 b7e145fbabacce397c045e2cb23e18af 229 Gene3D G3DSA:1.10.3720.10 14 228 7.6E-43 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0177 b7e145fbabacce397c045e2cb23e18af 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 228 2.4E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_0967 c33f938b14449280cc35b121666abaf8 137 SUPERFAMILY SSF143100 1 61 1.96E-15 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like MCR_0967 c33f938b14449280cc35b121666abaf8 137 Gene3D G3DSA:1.10.260.40 77 137 1.4E-6 T 14-10-2018 MCR_0967 c33f938b14449280cc35b121666abaf8 137 Gene3D G3DSA:3.30.160.250 1 73 5.3E-17 T 14-10-2018 MCR_0967 c33f938b14449280cc35b121666abaf8 137 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 67 8.5E-10 T 14-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system MCR_0967 c33f938b14449280cc35b121666abaf8 137 SUPERFAMILY SSF47413 79 134 1.62E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MCR_1020 cb3bf5e01c60d7820fdfa2629518df78 271 SUPERFAMILY SSF56219 4 271 5.89E-77 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MCR_1020 cb3bf5e01c60d7820fdfa2629518df78 271 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 262 3.0E-17 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MCR_1020 cb3bf5e01c60d7820fdfa2629518df78 271 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 270 1.2E-75 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MCR_1020 cb3bf5e01c60d7820fdfa2629518df78 271 Gene3D G3DSA:3.60.10.10 4 270 2.6E-68 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MCR_1020 cb3bf5e01c60d7820fdfa2629518df78 271 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 14-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 MCR_1020 cb3bf5e01c60d7820fdfa2629518df78 271 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 4 269 4.2E-86 T 14-10-2018 MCR_0336 4c39e0d8117ad93771d3125c0255380c 236 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 17 233 9.5E-65 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MCR_0336 4c39e0d8117ad93771d3125c0255380c 236 Pfam PF01168 Alanine racemase, N-terminal domain 32 233 2.8E-28 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MCR_0336 4c39e0d8117ad93771d3125c0255380c 236 SUPERFAMILY SSF51419 8 231 6.02E-68 T 14-10-2018 IPR029066 PLP-binding barrel MCR_0336 4c39e0d8117ad93771d3125c0255380c 236 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 14 232 29.492 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MCR_0336 4c39e0d8117ad93771d3125c0255380c 236 PIRSF PIRSF004848 6 236 5.5E-67 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MCR_0336 4c39e0d8117ad93771d3125c0255380c 236 Gene3D G3DSA:3.20.20.10 2 236 1.0E-69 T 14-10-2018 IPR029066 PLP-binding barrel MCR_0170 72f9dc9ab54f165e71e442ffefa51bee 236 SUPERFAMILY SSF50249 1 177 2.23E-47 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MCR_0170 72f9dc9ab54f165e71e442ffefa51bee 236 Hamap MF_00984 Single-stranded DNA-binding protein. 3 112 37.599 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MCR_0170 72f9dc9ab54f165e71e442ffefa51bee 236 Pfam PF00436 Single-strand binding protein family 3 108 1.7E-39 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MCR_0170 72f9dc9ab54f165e71e442ffefa51bee 236 Gene3D G3DSA:2.40.50.140 1 123 5.0E-45 T 14-10-2018 MCR_0170 72f9dc9ab54f165e71e442ffefa51bee 236 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 236 7.4E-47 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MCR_0613 a32f4e1812d8ab566bad85dc434a1aea 617 Pfam PF00639 PPIC-type PPIASE domain 275 355 2.0E-18 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 MCR_0613 a32f4e1812d8ab566bad85dc434a1aea 617 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 293 313 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 MCR_0613 a32f4e1812d8ab566bad85dc434a1aea 617 Pfam PF13624 SurA N-terminal domain 1 159 8.6E-29 T 14-10-2018 MCR_0613 a32f4e1812d8ab566bad85dc434a1aea 617 SUPERFAMILY SSF54534 259 355 1.64E-21 T 14-10-2018 MCR_0613 a32f4e1812d8ab566bad85dc434a1aea 617 Gene3D G3DSA:3.10.50.40 259 392 1.1E-23 T 14-10-2018 MCR_0613 a32f4e1812d8ab566bad85dc434a1aea 617 SUPERFAMILY SSF109998 42 234 3.02E-19 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily MCR_0558 fed0ae4850cfc3d3d118faeeebfd47d1 501 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0558 fed0ae4850cfc3d3d118faeeebfd47d1 501 PRINTS PR00175 Sodium/alanine symporter signature 220 239 3.2E-53 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0558 fed0ae4850cfc3d3d118faeeebfd47d1 501 PRINTS PR00175 Sodium/alanine symporter signature 369 391 3.2E-53 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0558 fed0ae4850cfc3d3d118faeeebfd47d1 501 PRINTS PR00175 Sodium/alanine symporter signature 432 452 3.2E-53 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0558 fed0ae4850cfc3d3d118faeeebfd47d1 501 PRINTS PR00175 Sodium/alanine symporter signature 307 325 3.2E-53 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0558 fed0ae4850cfc3d3d118faeeebfd47d1 501 PRINTS PR00175 Sodium/alanine symporter signature 86 108 3.2E-53 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0558 fed0ae4850cfc3d3d118faeeebfd47d1 501 PRINTS PR00175 Sodium/alanine symporter signature 192 210 3.2E-53 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0558 fed0ae4850cfc3d3d118faeeebfd47d1 501 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 466 1.3E-121 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0558 fed0ae4850cfc3d3d118faeeebfd47d1 501 Pfam PF01235 Sodium:alanine symporter family 51 475 3.6E-137 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0318 c2cf0e16463cfc58e7aa60e95643e17e 259 SUPERFAMILY SSF51556 4 253 2.32E-54 T 14-10-2018 IPR032466 Metal-dependent hydrolase MCR_0318 c2cf0e16463cfc58e7aa60e95643e17e 259 PIRSF PIRSF005902 1 255 1.8E-45 T 14-10-2018 IPR001130 TatD family GO:0016788 MCR_0318 c2cf0e16463cfc58e7aa60e95643e17e 259 Gene3D G3DSA:3.20.20.140 1 253 3.8E-54 T 14-10-2018 MCR_0318 c2cf0e16463cfc58e7aa60e95643e17e 259 Pfam PF01026 TatD related DNase 5 251 2.3E-44 T 14-10-2018 IPR001130 TatD family GO:0016788 MCR_0598 eb78b409da7fe45115b56fbd9d9b25d8 188 Pfam PF00857 Isochorismatase family 6 181 2.8E-34 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 MCR_0598 eb78b409da7fe45115b56fbd9d9b25d8 188 SUPERFAMILY SSF52499 3 184 1.2E-48 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MCR_0598 eb78b409da7fe45115b56fbd9d9b25d8 188 Gene3D G3DSA:3.40.50.850 1 187 3.6E-57 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MCR_0530 8e98660bf021ba17f03f1070f67cfd38 127 Pfam PF04241 Protein of unknown function (DUF423) 21 106 2.1E-26 T 14-10-2018 IPR006696 Protein of unknown function DUF423 MCR_0916 bd792e2c6df7bdda900ae221baa2c73d 252 Pfam PF06912 Protein of unknown function (DUF1275) 16 212 3.6E-29 T 14-10-2018 IPR010699 Protein of unknown function DUF1275 MCR_1384 cdfd2c3effb602aa00f7ec7ea3ad17e9 282 SUPERFAMILY SSF53271 109 267 1.1E-18 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MCR_1384 cdfd2c3effb602aa00f7ec7ea3ad17e9 282 Gene3D G3DSA:3.40.50.2020 142 280 4.9E-12 T 14-10-2018 MCR_0174 c3e589f8a33e4e33b77d1bab947d748f 66 Pfam PF04995 Heme exporter protein D (CcmD) 15 58 4.9E-14 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 MCR_0174 c3e589f8a33e4e33b77d1bab947d748f 66 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 12 57 2.9E-16 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 MCR_0579 38688a736d85a323b21288884493cd2b 251 Pfam PF05096 Glutamine cyclotransferase 24 247 6.8E-66 T 14-10-2018 IPR007788 Glutaminyl-peptide cyclotransferase GO:0016603|GO:0017186 MetaCyc: PWY-7942 MCR_0579 38688a736d85a323b21288884493cd2b 251 SUPERFAMILY SSF50969 23 210 4.08E-16 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like MCR_0579 38688a736d85a323b21288884493cd2b 251 Gene3D G3DSA:2.130.10.10 22 223 1.0E-6 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MCR_0048 38b876129f3131b64c8db6bb9a8cb4ec 397 SUPERFAMILY SSF53383 1 387 3.2E-71 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0048 38b876129f3131b64c8db6bb9a8cb4ec 397 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 387 3.1E-70 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MCR_0048 38b876129f3131b64c8db6bb9a8cb4ec 397 PIRSF PIRSF001434 1 391 5.6E-94 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MCR_0048 38b876129f3131b64c8db6bb9a8cb4ec 397 Gene3D G3DSA:3.40.640.10 3 255 1.0E-52 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_0048 38b876129f3131b64c8db6bb9a8cb4ec 397 Gene3D G3DSA:3.90.1150.10 256 390 5.2E-26 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_0124 e4843c391fa703674f66b426b1b42ce6 562 Gene3D G3DSA:3.20.20.70 148 514 9.4E-106 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0124 e4843c391fa703674f66b426b1b42ce6 562 PIRSF PIRSF500060 20 538 2.6E-219 T 14-10-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria MCR_0124 e4843c391fa703674f66b426b1b42ce6 562 SUPERFAMILY SSF51395 26 503 3.09E-134 T 14-10-2018 MCR_0124 e4843c391fa703674f66b426b1b42ce6 562 Pfam PF01645 Conserved region in glutamate synthase 153 480 2.8E-85 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MCR_0124 e4843c391fa703674f66b426b1b42ce6 562 PIRSF PIRSF006429 17 545 5.9E-159 T 14-10-2018 IPR024188 Glutamate synthase large subunit-like protein MCR_0063 291900b5e9b92574cead88ad41d74142 232 Gene3D G3DSA:1.20.1260.10 73 227 2.4E-42 T 14-10-2018 IPR012347 Ferritin-like MCR_0063 291900b5e9b92574cead88ad41d74142 232 Pfam PF03713 Domain of unknown function (DUF305) 126 225 1.1E-20 T 14-10-2018 IPR005183 Domain of unknown function DUF305 MCR_1566 235a11b65b5476e021619948f2897090 146 SUPERFAMILY SSF52080 6 145 5.49E-44 T 14-10-2018 IPR036227 Ribosomal L18e/L15P superfamily MCR_1566 235a11b65b5476e021619948f2897090 146 Gene3D G3DSA:3.100.10.10 72 146 3.2E-14 T 14-10-2018 MCR_1566 235a11b65b5476e021619948f2897090 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 111 141 - T 14-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1566 235a11b65b5476e021619948f2897090 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 30 145 5.7E-29 T 14-10-2018 IPR021131 Ribosomal protein L18e/L15P MCR_1566 235a11b65b5476e021619948f2897090 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 4 145 3.7E-46 T 14-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MCR_1566 235a11b65b5476e021619948f2897090 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 146 18.007 T 14-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 MCR_1105 0f6b513aeec46250897b8c056741108f 288 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 17 286 70.582 T 14-10-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein MCR_1105 0f6b513aeec46250897b8c056741108f 288 Pfam PF03618 Kinase/pyrophosphorylase 21 277 9.7E-73 T 14-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 MCR_1832 b9540a8498da3adb390aff4ce88fd7bf 295 SUPERFAMILY SSF52540 10 164 1.92E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1832 b9540a8498da3adb390aff4ce88fd7bf 295 PIRSF PIRSF005052 8 294 1.8E-93 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 MCR_1832 b9540a8498da3adb390aff4ce88fd7bf 295 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 8 294 36.002 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 MCR_1832 b9540a8498da3adb390aff4ce88fd7bf 295 Pfam PF03668 P-loop ATPase protein family 10 290 2.3E-81 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 MCR_0515 93c7c9902db6479fd86023711fbc9e51 282 Gene3D G3DSA:3.40.50.720 1 281 6.7E-48 T 14-10-2018 MCR_0515 93c7c9902db6479fd86023711fbc9e51 282 SUPERFAMILY SSF51735 4 253 4.12E-18 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MCR_0957 88c2482aae6f9d688dda024f8dafc15a 263 Pfam PF10552 ORF6C domain 127 173 5.2E-8 T 14-10-2018 IPR018878 ORF6C domain MCR_0957 88c2482aae6f9d688dda024f8dafc15a 263 Pfam PF02498 BRO family, N-terminal domain 14 100 1.3E-18 T 14-10-2018 IPR003497 BRO N-terminal domain MCR_0957 88c2482aae6f9d688dda024f8dafc15a 263 SMART SM01040 14 100 3.6E-24 T 14-10-2018 IPR003497 BRO N-terminal domain MCR_1784 35a6094aa0188364e9cb3ce2141e73c2 257 SUPERFAMILY SSF51366 1 255 1.18E-83 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MCR_1784 35a6094aa0188364e9cb3ce2141e73c2 257 Pfam PF00977 Histidine biosynthesis protein 5 239 1.3E-88 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 MCR_1784 35a6094aa0188364e9cb3ce2141e73c2 257 Gene3D G3DSA:3.20.20.70 1 257 2.8E-109 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1784 35a6094aa0188364e9cb3ce2141e73c2 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 255 48.032 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MCR_1784 35a6094aa0188364e9cb3ce2141e73c2 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 255 3.4E-112 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MCR_1230 e1ae473ee80278511ae017a6fbd8a009 274 SUPERFAMILY SSF81901 154 246 7.85E-9 T 14-10-2018 MCR_1230 e1ae473ee80278511ae017a6fbd8a009 274 Gene3D G3DSA:1.25.40.10 113 251 6.0E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0506 d654e8b4cbad1e77addd58cf3319558e 145 SUPERFAMILY SSF52833 13 132 1.36E-22 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0506 d654e8b4cbad1e77addd58cf3319558e 145 Pfam PF00578 AhpC/TSA family 14 109 9.0E-12 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MCR_0506 d654e8b4cbad1e77addd58cf3319558e 145 Gene3D G3DSA:3.40.30.10 12 127 2.1E-21 T 14-10-2018 MCR_0198 259aef6b3a58104b8235f56fdf023d61 256 Gene3D G3DSA:3.40.50.150 23 256 2.1E-49 T 14-10-2018 MCR_0198 259aef6b3a58104b8235f56fdf023d61 256 SUPERFAMILY SSF53335 24 256 4.3E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0198 259aef6b3a58104b8235f56fdf023d61 256 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 9 256 5.3E-68 T 14-10-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MCR_0198 259aef6b3a58104b8235f56fdf023d61 256 Hamap MF_01589 Carboxy-S-adenosyl-L-methionine synthase [cmoA]. 8 256 35.083 T 14-10-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MCR_0198 259aef6b3a58104b8235f56fdf023d61 256 Pfam PF13649 Methyltransferase domain 74 172 1.0E-10 T 14-10-2018 MCR_0198 259aef6b3a58104b8235f56fdf023d61 256 PIRSF PIRSF006325 6 256 1.4E-75 T 14-10-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MCR_1691 6bb5f7d502d221c88d3c8fbdb662788f 267 SMART SM00079 44 262 0.0024 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MCR_1691 6bb5f7d502d221c88d3c8fbdb662788f 267 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 67 80 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site MCR_1691 6bb5f7d502d221c88d3c8fbdb662788f 267 SUPERFAMILY SSF53850 3 261 1.6E-67 T 14-10-2018 MCR_1691 6bb5f7d502d221c88d3c8fbdb662788f 267 Gene3D G3DSA:3.40.190.10 130 220 8.6E-68 T 14-10-2018 MCR_1691 6bb5f7d502d221c88d3c8fbdb662788f 267 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 261 3.8E-62 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MCR_1691 6bb5f7d502d221c88d3c8fbdb662788f 267 Gene3D G3DSA:3.40.190.10 47 260 8.6E-68 T 14-10-2018 MCR_1691 6bb5f7d502d221c88d3c8fbdb662788f 267 SMART SM00062 44 263 1.6E-63 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MCR_1695 5a4c12e42da225200c0fe188be502765 241 Gene3D G3DSA:1.10.3720.10 1 228 1.3E-49 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1695 5a4c12e42da225200c0fe188be502765 241 SUPERFAMILY SSF161098 13 210 1.83E-40 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1695 5a4c12e42da225200c0fe188be502765 241 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 225 7.7E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_1695 5a4c12e42da225200c0fe188be502765 241 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 119 3.4E-23 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MCR_1358 f31aa034afd6768d52f5b07e1fdbf067 207 SUPERFAMILY SSF47616 82 203 1.32E-13 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MCR_1358 f31aa034afd6768d52f5b07e1fdbf067 207 SUPERFAMILY SSF52833 21 107 1.58E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_1358 f31aa034afd6768d52f5b07e1fdbf067 207 Gene3D G3DSA:1.20.1050.10 89 196 2.4E-53 T 14-10-2018 MCR_1358 f31aa034afd6768d52f5b07e1fdbf067 207 Pfam PF02798 Glutathione S-transferase, N-terminal domain 12 79 1.3E-9 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MCR_1358 f31aa034afd6768d52f5b07e1fdbf067 207 Gene3D G3DSA:3.40.30.10 18 199 2.4E-53 T 14-10-2018 MCR_0942 d6ed2aa244038de0ddf5b63e138fb509 320 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 144 244 1.3E-12 T 14-10-2018 IPR006528 Phage head morphogenesis domain MCR_0942 d6ed2aa244038de0ddf5b63e138fb509 320 Pfam PF04233 Phage Mu protein F like protein 132 244 1.0E-9 T 14-10-2018 IPR006528 Phage head morphogenesis domain MCR_0367 5352ed18e4eb4ae759fc61016ec9ac61 305 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 6 284 4.5E-83 T 14-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 MCR_0367 5352ed18e4eb4ae759fc61016ec9ac61 305 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 8 270 1.4E-46 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 MCR_0367 5352ed18e4eb4ae759fc61016ec9ac61 305 Gene3D G3DSA:3.40.50.620 6 294 7.9E-88 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0367 5352ed18e4eb4ae759fc61016ec9ac61 305 SUPERFAMILY SSF52374 6 300 2.65E-64 T 14-10-2018 MCR_0367 5352ed18e4eb4ae759fc61016ec9ac61 305 Gene3D G3DSA:3.40.50.620 80 231 7.9E-88 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0367 5352ed18e4eb4ae759fc61016ec9ac61 305 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 2.3E-11 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_0367 5352ed18e4eb4ae759fc61016ec9ac61 305 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 2.3E-11 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_0367 5352ed18e4eb4ae759fc61016ec9ac61 305 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 206 2.3E-11 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_0367 5352ed18e4eb4ae759fc61016ec9ac61 305 PRINTS PR00987 Glutamyl-tRNA synthetase signature 182 192 2.3E-11 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MCR_1837 a107ee9fc562754fbaf119a192103453 112 Gene3D G3DSA:1.10.150.280 39 111 6.0E-20 T 14-10-2018 MCR_1837 a107ee9fc562754fbaf119a192103453 112 Pfam PF12836 Helix-hairpin-helix motif 46 108 1.4E-19 T 14-10-2018 MCR_1837 a107ee9fc562754fbaf119a192103453 112 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 45 109 9.5E-20 T 14-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain MCR_1837 a107ee9fc562754fbaf119a192103453 112 SUPERFAMILY SSF47781 37 110 2.22E-23 T 14-10-2018 IPR010994 RuvA domain 2-like MCR_0818 b6941d4d5990a4c35821913304477860 347 SUPERFAMILY SSF52540 54 175 2.02E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0818 b6941d4d5990a4c35821913304477860 347 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 20 339 1.9E-99 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 MCR_0818 b6941d4d5990a4c35821913304477860 347 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 28 328 3.8E-62 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 MCR_0818 b6941d4d5990a4c35821913304477860 347 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 9 345 35.973 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 MCR_1492 2041e68802fea3e6ee515abc65d1211a 292 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 5 290 4.3E-77 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MCR_1492 2041e68802fea3e6ee515abc65d1211a 292 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 138 150 - T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MCR_1492 2041e68802fea3e6ee515abc65d1211a 292 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 10 278 9.6E-71 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MCR_1492 2041e68802fea3e6ee515abc65d1211a 292 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 284 18.988 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MCR_1084 78702e96a41ac5679a06208cc91b9380 509 SUPERFAMILY SSF103473 14 500 1.57E-44 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_1084 78702e96a41ac5679a06208cc91b9380 509 Pfam PF07690 Major Facilitator Superfamily 20 464 9.1E-21 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MCR_0568 70869ac7057004bf5d10957574db3788 219 Gene3D G3DSA:3.40.109.10 3 219 2.5E-61 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MCR_0568 70869ac7057004bf5d10957574db3788 219 Pfam PF00881 Nitroreductase family 15 198 9.5E-28 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MCR_0568 70869ac7057004bf5d10957574db3788 219 SUPERFAMILY SSF55469 8 216 5.23E-53 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MCR_0083 a555fd4076b3caeb8836594aff2b5aa0 77 Pfam PF09526 Probable metal-binding protein (DUF2387) 8 65 1.9E-17 T 14-10-2018 IPR012658 Conserved hypothetical protein CHP02443 MCR_1495 864f1d6403f21b45a5f8b384a738fe46 226 Pfam PF11306 Protein of unknown function (DUF3108) 18 224 3.3E-24 T 14-10-2018 IPR021457 Protein of unknown function DUF3108 MCR_0280 85ca313ec0a9df8558f49b99af1a7107 367 Gene3D G3DSA:3.40.50.2000 165 327 3.9E-110 T 14-10-2018 MCR_0280 85ca313ec0a9df8558f49b99af1a7107 367 Gene3D G3DSA:3.40.50.2000 8 164 3.9E-110 T 14-10-2018 MCR_0280 85ca313ec0a9df8558f49b99af1a7107 367 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 7 361 34.706 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0280 85ca313ec0a9df8558f49b99af1a7107 367 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 7 144 1.6E-41 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0280 85ca313ec0a9df8558f49b99af1a7107 367 SUPERFAMILY SSF53756 6 360 1.3E-117 T 14-10-2018 MCR_0280 85ca313ec0a9df8558f49b99af1a7107 367 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 349 7.8E-40 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 MCR_0280 85ca313ec0a9df8558f49b99af1a7107 367 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 356 6.0E-105 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_1120 841acc9b6382cac57c472f1339d667ea 141 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 53 138 1.0E-29 T 14-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 MCR_1120 841acc9b6382cac57c472f1339d667ea 141 Gene3D G3DSA:1.20.120.1630 3 141 4.1E-18 T 14-10-2018 MCR_1165 6da19b84fd2d28310e51f215133edd9f 239 Pfam PF01351 Ribonuclease HII 21 221 1.3E-34 T 14-10-2018 IPR024567 Ribonuclease HII/HIII domain MCR_1165 6da19b84fd2d28310e51f215133edd9f 239 SUPERFAMILY SSF53098 14 231 1.27E-56 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MCR_1165 6da19b84fd2d28310e51f215133edd9f 239 Hamap MF_00052_B Ribonuclease HII [rnhB]. 19 223 32.19 T 14-10-2018 IPR022898 Ribonuclease HII GO:0004523 MCR_1165 6da19b84fd2d28310e51f215133edd9f 239 Gene3D G3DSA:3.30.420.10 5 238 6.6E-64 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MCR_0770 5db5545cac1c582e602975ead7bc2aed 303 Pfam PF04829 Pre-toxin domain with VENN motif 10 56 2.8E-8 T 14-10-2018 IPR006914 VENN motif-containing domain MCR_0197 fb759c1c6c6137b9cc36b5d72f19642e 177 Pfam PF01625 Peptide methionine sulfoxide reductase 3 153 3.5E-59 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MCR_0197 fb759c1c6c6137b9cc36b5d72f19642e 177 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 157 34.41 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MCR_0197 fb759c1c6c6137b9cc36b5d72f19642e 177 Gene3D G3DSA:3.30.1060.10 1 160 6.9E-64 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MCR_0197 fb759c1c6c6137b9cc36b5d72f19642e 177 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 152 3.5E-52 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MCR_0197 fb759c1c6c6137b9cc36b5d72f19642e 177 SUPERFAMILY SSF55068 1 163 5.49E-66 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MCR_1144 12e6b41378cc6d04733895d34fe69036 464 Pfam PF11981 Domain of unknown function (DUF3482) 173 450 2.0E-81 T 14-10-2018 IPR021871 Protein of unknown function DUF3482 MCR_1144 12e6b41378cc6d04733895d34fe69036 464 Gene3D G3DSA:3.40.50.300 6 221 4.6E-23 T 14-10-2018 MCR_1144 12e6b41378cc6d04733895d34fe69036 464 Pfam PF01926 50S ribosome-binding GTPase 11 160 2.0E-13 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MCR_1144 12e6b41378cc6d04733895d34fe69036 464 SUPERFAMILY SSF52540 6 181 2.86E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0525 a89c390d9504c5ee6849c37dec114fa2 252 ProSitePatterns PS00211 ABC transporters family signature. 175 189 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_0525 a89c390d9504c5ee6849c37dec114fa2 252 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 58 245 9.9E-43 T 14-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 MCR_0525 a89c390d9504c5ee6849c37dec114fa2 252 SUPERFAMILY SSF52540 56 237 5.45E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0525 a89c390d9504c5ee6849c37dec114fa2 252 SMART SM00382 82 249 0.0057 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_0525 a89c390d9504c5ee6849c37dec114fa2 252 Gene3D G3DSA:3.40.50.300 46 247 6.5E-36 T 14-10-2018 MCR_0525 a89c390d9504c5ee6849c37dec114fa2 252 Pfam PF00005 ABC transporter 74 205 4.9E-15 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1720 93e74221291686d13b91baea778ecc1a 330 SUPERFAMILY SSF51679 4 326 2.49E-77 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MCR_1720 93e74221291686d13b91baea778ecc1a 330 Pfam PF00296 Luciferase-like monooxygenase 20 296 5.9E-29 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MCR_1720 93e74221291686d13b91baea778ecc1a 330 Gene3D G3DSA:3.20.20.30 1 328 4.0E-94 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MCR_1720 93e74221291686d13b91baea778ecc1a 330 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 324 1.8E-124 T 14-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 MCR_0107 20fed4cccf56a586745229253a7d8e89 258 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 119 136 3.6E-15 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MCR_0107 20fed4cccf56a586745229253a7d8e89 258 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 187 198 3.6E-15 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MCR_0107 20fed4cccf56a586745229253a7d8e89 258 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 199 214 3.6E-15 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MCR_0107 20fed4cccf56a586745229253a7d8e89 258 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 176 186 3.6E-15 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MCR_0107 20fed4cccf56a586745229253a7d8e89 258 Pfam PF01478 Type IV leader peptidase family 111 219 6.3E-19 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 MCR_0802 acc3accdd01c100275920fbbe460aceb 456 Pfam PF13726 Na+-H+ antiporter family 22 108 3.4E-32 T 14-10-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal MCR_0802 acc3accdd01c100275920fbbe460aceb 456 Pfam PF03553 Na+/H+ antiporter family 168 450 1.3E-71 T 14-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MCR_0712 cc0806510b4d326f16be5d66c9877e0a 169 PIRSF PIRSF000216 3 169 1.6E-43 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0712 cc0806510b4d326f16be5d66c9877e0a 169 SUPERFAMILY SSF52833 18 168 1.23E-43 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0712 cc0806510b4d326f16be5d66c9877e0a 169 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 25 168 1.5E-43 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0712 cc0806510b4d326f16be5d66c9877e0a 169 Gene3D G3DSA:3.40.30.10 86 168 1.8E-20 T 14-10-2018 MCR_0712 cc0806510b4d326f16be5d66c9877e0a 169 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 26 168 1.9E-42 T 14-10-2018 MCR_0712 cc0806510b4d326f16be5d66c9877e0a 169 Gene3D G3DSA:1.10.10.1590 17 85 4.7E-16 T 14-10-2018 MCR_1636 c3d9b231ecd8cfbad4e7ee3efe3c57d6 354 Gene3D G3DSA:3.30.460.10 21 167 7.9E-30 T 14-10-2018 MCR_1636 c3d9b231ecd8cfbad4e7ee3efe3c57d6 354 SMART SM00954 66 186 1.3E-21 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MCR_1636 c3d9b231ecd8cfbad4e7ee3efe3c57d6 354 Pfam PF04607 Region found in RelA / SpoT proteins 66 175 7.8E-20 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MCR_1636 c3d9b231ecd8cfbad4e7ee3efe3c57d6 354 SUPERFAMILY SSF81301 32 205 5.07E-31 T 14-10-2018 MCR_0519 3f717e3c6a688534121e59aee642cd9a 259 Pfam PF06044 Dam-replacing family 1 253 1.8E-124 T 14-10-2018 IPR010324 Dam-replacing MCR_0519 3f717e3c6a688534121e59aee642cd9a 259 Gene3D G3DSA:1.10.10.10 165 254 5.3E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0519 3f717e3c6a688534121e59aee642cd9a 259 Gene3D G3DSA:3.40.210.30 1 164 5.1E-73 T 14-10-2018 MCR_1160 c29ebbf376f94c3aa885e8ffbd2ce1d6 134 Pfam PF05768 Glutaredoxin-like domain (DUF836) 51 108 4.4E-6 T 14-10-2018 IPR008554 Glutaredoxin-like MCR_1160 c29ebbf376f94c3aa885e8ffbd2ce1d6 134 Gene3D G3DSA:3.40.30.10 49 131 1.2E-9 T 14-10-2018 MCR_1160 c29ebbf376f94c3aa885e8ffbd2ce1d6 134 SUPERFAMILY SSF52833 51 116 2.57E-5 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_1135 d3ce99d7a55eaf8c8e7370ce353e33ef 358 Pfam PF04332 Protein of unknown function (DUF475) 50 355 1.4E-118 T 14-10-2018 IPR007427 Protein of unknown function DUF475 MCR_1067 79cb96484c041d447f6ed0a78ec0a8ec 437 Pfam PF00860 Permease family 17 397 3.7E-81 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MCR_0711 b00b36e216ba921dd17fd87862b6be51 255 Pfam PF01925 Sulfite exporter TauE/SafE 8 246 2.2E-25 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MCR_1792 6c8c9e6da22c4a60486ebc7e933e917c 199 SUPERFAMILY SSF53335 2 116 5.74E-10 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1792 6c8c9e6da22c4a60486ebc7e933e917c 199 Gene3D G3DSA:3.40.50.150 1 174 5.7E-12 T 14-10-2018 MCR_0449 62765c26c3e2dc48c34957df2422078a 392 Pfam PF00487 Fatty acid desaturase 48 267 4.0E-19 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MCR_0449 62765c26c3e2dc48c34957df2422078a 392 PRINTS PR00075 Fatty acid desaturase family 1 signature 194 215 1.2E-30 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 MCR_0449 62765c26c3e2dc48c34957df2422078a 392 PRINTS PR00075 Fatty acid desaturase family 1 signature 237 251 1.2E-30 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 MCR_0449 62765c26c3e2dc48c34957df2422078a 392 PRINTS PR00075 Fatty acid desaturase family 1 signature 44 66 1.2E-30 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 MCR_0449 62765c26c3e2dc48c34957df2422078a 392 PRINTS PR00075 Fatty acid desaturase family 1 signature 67 87 1.2E-30 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 MCR_0449 62765c26c3e2dc48c34957df2422078a 392 PRINTS PR00075 Fatty acid desaturase family 1 signature 105 134 1.2E-30 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 MCR_0449 62765c26c3e2dc48c34957df2422078a 392 PIRSF PIRSF000345 4 311 2.1E-94 T 14-10-2018 IPR009160 Acyl-CoA desaturase, haem/steroid binding domain-containing GO:0004768|GO:0006636|GO:0016021 MetaCyc: PWY-5987|MetaCyc: PWY-5996 MCR_0699 5d0b71dd23c17144e5d7c292cf296c00 301 SUPERFAMILY SSF53474 19 290 1.75E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0699 5d0b71dd23c17144e5d7c292cf296c00 301 Pfam PF00561 alpha/beta hydrolase fold 71 257 2.6E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MCR_0699 5d0b71dd23c17144e5d7c292cf296c00 301 Gene3D G3DSA:3.40.50.1820 1 298 4.6E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_1162 0751c0c998ef3ddc67bc02bac276b9fe 388 SUPERFAMILY SSF51569 41 383 6.18E-129 T 14-10-2018 MCR_1162 0751c0c998ef3ddc67bc02bac276b9fe 388 Pfam PF00793 DAHP synthetase I family 78 373 7.0E-93 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MCR_1162 0751c0c998ef3ddc67bc02bac276b9fe 388 Gene3D G3DSA:3.20.20.70 35 385 1.6E-151 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_1162 0751c0c998ef3ddc67bc02bac276b9fe 388 PIRSF PIRSF001361 28 388 7.0E-157 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MCR_1162 0751c0c998ef3ddc67bc02bac276b9fe 388 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 40 383 7.4E-149 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MCR_0526 7534b32c021fc7a8c5482811642f2171 224 Pfam PF03379 CcmB protein 7 219 1.4E-42 T 14-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 MCR_0526 7534b32c021fc7a8c5482811642f2171 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 56 73 1.2E-35 T 14-10-2018 MCR_0526 7534b32c021fc7a8c5482811642f2171 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 196 219 1.2E-35 T 14-10-2018 MCR_0526 7534b32c021fc7a8c5482811642f2171 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 104 122 1.2E-35 T 14-10-2018 MCR_0526 7534b32c021fc7a8c5482811642f2171 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 159 178 1.2E-35 T 14-10-2018 MCR_0526 7534b32c021fc7a8c5482811642f2171 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 30 51 1.2E-35 T 14-10-2018 MCR_0526 7534b32c021fc7a8c5482811642f2171 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 79 102 1.2E-35 T 14-10-2018 MCR_0526 7534b32c021fc7a8c5482811642f2171 224 PIRSF PIRSF002764 1 223 5.1E-67 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria MCR_0929 8b3b73dbcf9daee5622c66c53fbcf382 1315 Pfam PF13361 UvrD-like helicase C-terminal domain 533 928 1.1E-27 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MCR_0929 8b3b73dbcf9daee5622c66c53fbcf382 1315 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 17 1315 13.486 T 14-10-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 MCR_0929 8b3b73dbcf9daee5622c66c53fbcf382 1315 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1060 1267 1.6E-5 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type MCR_0929 8b3b73dbcf9daee5622c66c53fbcf382 1315 Gene3D G3DSA:1.10.486.10 673 833 5.6E-51 T 14-10-2018 MCR_0929 8b3b73dbcf9daee5622c66c53fbcf382 1315 Gene3D G3DSA:3.40.50.300 21 512 5.6E-55 T 14-10-2018 MCR_0929 8b3b73dbcf9daee5622c66c53fbcf382 1315 SUPERFAMILY SSF52540 16 934 8.73E-92 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0929 8b3b73dbcf9daee5622c66c53fbcf382 1315 Gene3D G3DSA:1.10.3170.10 192 410 5.6E-55 T 14-10-2018 MCR_0929 8b3b73dbcf9daee5622c66c53fbcf382 1315 Gene3D G3DSA:3.40.50.300 537 940 5.6E-51 T 14-10-2018 MCR_0929 8b3b73dbcf9daee5622c66c53fbcf382 1315 Pfam PF00580 UvrD/REP helicase N-terminal domain 17 513 4.3E-47 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MCR_0929 8b3b73dbcf9daee5622c66c53fbcf382 1315 SUPERFAMILY SSF52980 1008 1315 1.13E-47 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MCR_0929 8b3b73dbcf9daee5622c66c53fbcf382 1315 Gene3D G3DSA:3.90.320.10 1006 1315 4.9E-52 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal MCR_1634 5f03a8790d267fb24f954f8eaacc8400 69 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 13 59 3.4E-12 T 14-10-2018 IPR010260 DNA-binding transcriptional activator AlpA MCR_1575 184589277e40458c60112a073f678a28 122 SMART SM01374 1 122 1.1E-85 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MCR_1575 184589277e40458c60112a073f678a28 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 14-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MCR_1575 184589277e40458c60112a073f678a28 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.351 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MCR_1575 184589277e40458c60112a073f678a28 122 Gene3D G3DSA:2.40.150.20 1 122 7.1E-55 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 MCR_1575 184589277e40458c60112a073f678a28 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 8.3E-55 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MCR_1575 184589277e40458c60112a073f678a28 122 SUPERFAMILY SSF50193 1 122 3.4E-51 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 MCR_1575 184589277e40458c60112a073f678a28 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.7E-58 T 14-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 MCR_0631 b70c9791574c02a88ff2c00aee6e45b8 96 Pfam PF07023 Protein of unknown function (DUF1315) 4 89 8.6E-33 T 14-10-2018 IPR009749 Protein of unknown function DUF1315 MCR_0650 2d3c5af541411cd06f04c77e16ecae46 414 Pfam PF12704 MacB-like periplasmic core domain 27 218 5.3E-15 T 14-10-2018 IPR025857 MacB-like periplasmic core domain MCR_0650 2d3c5af541411cd06f04c77e16ecae46 414 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 414 3.0E-145 T 14-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 MCR_0650 2d3c5af541411cd06f04c77e16ecae46 414 Pfam PF02687 FtsX-like permease family 299 407 2.6E-11 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MCR_0441 64cb29ae18cd5a08e33271d0224071ae 476 Pfam PF01650 Peptidase C13 family 288 438 3.5E-25 T 14-10-2018 IPR001096 Peptidase C13, legumain GO:0006508|GO:0008233 MCR_0425 804952ca0e1fbdbd793f291d8d268507 173 Pfam PF03695 Uncharacterised protein family (UPF0149) 5 170 2.8E-14 T 14-10-2018 IPR011978 Uncharacterised protein family UPF0149 MCR_0425 804952ca0e1fbdbd793f291d8d268507 173 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 6 168 3.9E-9 T 14-10-2018 IPR011978 Uncharacterised protein family UPF0149 MCR_0425 804952ca0e1fbdbd793f291d8d268507 173 SUPERFAMILY SSF101327 4 172 8.11E-18 T 14-10-2018 IPR036255 YgfB-like superfamily MCR_0469 4a2549941cecb794db90cfed2833323b 415 Pfam PF01594 AI-2E family transporter 14 347 9.2E-46 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like MCR_0359 78bf58c1306d891afbbf480111a287d5 458 Gene3D G3DSA:3.40.640.10 76 340 3.3E-132 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MCR_0359 78bf58c1306d891afbbf480111a287d5 458 SUPERFAMILY SSF53383 29 450 3.94E-121 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MCR_0359 78bf58c1306d891afbbf480111a287d5 458 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MCR_0359 78bf58c1306d891afbbf480111a287d5 458 Gene3D G3DSA:3.90.1150.10 28 443 3.3E-132 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MCR_0359 78bf58c1306d891afbbf480111a287d5 458 Pfam PF00202 Aminotransferase class-III 39 449 8.6E-98 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MCR_0359 78bf58c1306d891afbbf480111a287d5 458 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 21 457 3.3E-232 T 14-10-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 MCR_0131 d9214063693bbb250267e5ec0f0c4421 758 SUPERFAMILY SSF81442 277 747 9.81E-78 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_0131 d9214063693bbb250267e5ec0f0c4421 758 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 283 726 2.3E-66 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_0131 d9214063693bbb250267e5ec0f0c4421 758 Gene3D G3DSA:1.20.210.10 220 753 1.2E-164 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1306 6764b65975eca42aea41d3a7b0d8fa3c 308 SUPERFAMILY SSF161098 102 287 7.33E-22 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1306 6764b65975eca42aea41d3a7b0d8fa3c 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 72 5.5E-9 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MCR_1306 6764b65975eca42aea41d3a7b0d8fa3c 308 Gene3D G3DSA:1.10.3720.10 98 301 8.7E-14 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1306 6764b65975eca42aea41d3a7b0d8fa3c 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 305 4.0E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_1294 c7528517379e7018205c56b474176801 117 Pfam PF03960 ArsC family 6 115 9.4E-12 T 14-10-2018 IPR006660 Arsenate reductase-like MCR_1294 c7528517379e7018205c56b474176801 117 Gene3D G3DSA:3.40.30.10 2 117 3.4E-30 T 14-10-2018 MCR_1294 c7528517379e7018205c56b474176801 117 SUPERFAMILY SSF52833 3 116 6.55E-22 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MCR_0299 38d90891686a2129c6ea43e5356cfb5b 233 SUPERFAMILY SSF51197 43 228 1.28E-5 T 14-10-2018 MCR_0299 38d90891686a2129c6ea43e5356cfb5b 233 SMART SM00702 57 228 4.5E-11 T 14-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 MCR_0299 38d90891686a2129c6ea43e5356cfb5b 233 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 140 228 7.6E-21 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MCR_0299 38d90891686a2129c6ea43e5356cfb5b 233 Gene3D G3DSA:2.60.120.620 46 232 3.1E-43 T 14-10-2018 MCR_1497 95e0fafc12dd686cdde2f082522ce0b5 201 Pfam PF03358 NADPH-dependent FMN reductase 63 139 2.0E-9 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MCR_1497 95e0fafc12dd686cdde2f082522ce0b5 201 SUPERFAMILY SSF52218 5 196 3.15E-51 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MCR_1497 95e0fafc12dd686cdde2f082522ce0b5 201 Gene3D G3DSA:3.40.50.360 2 198 6.5E-55 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MCR_1788 fc35967d055009653bd81fe9b6a4ee66 182 Pfam PF03235 Protein of unknown function DUF262 7 150 1.3E-19 T 14-10-2018 IPR004919 Domain of unknown function DUF262 MCR_0289 ad1f07ed0b3fbe73d56ed15eb8b42fdd 77 Pfam PF04325 Protein of unknown function (DUF465) 20 67 3.5E-13 T 14-10-2018 IPR007420 Protein of unknown function DUF465 MCR_0289 ad1f07ed0b3fbe73d56ed15eb8b42fdd 77 Gene3D G3DSA:1.20.58.660 1 76 1.4E-19 T 14-10-2018 MCR_0885 debc05ba8c5148ff7a7fc2b95cc8b2c0 329 SUPERFAMILY SSF53474 29 327 4.46E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0885 debc05ba8c5148ff7a7fc2b95cc8b2c0 329 Pfam PF00561 alpha/beta hydrolase fold 54 197 1.4E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MCR_0885 debc05ba8c5148ff7a7fc2b95cc8b2c0 329 PRINTS PR00111 Alpha/beta hydrolase fold signature 273 287 9.8E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MCR_0885 debc05ba8c5148ff7a7fc2b95cc8b2c0 329 PRINTS PR00111 Alpha/beta hydrolase fold signature 151 164 9.8E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MCR_0885 debc05ba8c5148ff7a7fc2b95cc8b2c0 329 PRINTS PR00111 Alpha/beta hydrolase fold signature 165 178 9.8E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MCR_0885 debc05ba8c5148ff7a7fc2b95cc8b2c0 329 Gene3D G3DSA:3.40.50.1820 38 328 2.0E-52 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0964 0aa4b208a14e32d81e5ada64128b82ce 222 TIGRFAM TIGR01600 phage_tail_L: phage minor tail protein L 6 219 1.7E-40 T 14-10-2018 IPR006487 Bacteriophage lambda, GpL, minor tail MCR_0964 0aa4b208a14e32d81e5ada64128b82ce 222 Pfam PF05100 Phage minor tail protein L 26 221 5.0E-45 T 14-10-2018 IPR006487 Bacteriophage lambda, GpL, minor tail MCR_1037 8601b0d7308f1543327e751eb78337e5 252 Pfam PF06629 MltA-interacting protein MipA 33 252 1.4E-46 T 14-10-2018 IPR010583 MltA-interacting MipA MCR_1037 8601b0d7308f1543327e751eb78337e5 252 SUPERFAMILY SSF56925 71 252 1.57E-5 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MCR_0106 57d50f607750b3ec24230151fc963dd4 211 Gene3D G3DSA:3.40.50.300 1 208 2.8E-58 T 14-10-2018 MCR_0106 57d50f607750b3ec24230151fc963dd4 211 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 194 3.2E-44 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MCR_0106 57d50f607750b3ec24230151fc963dd4 211 Pfam PF01121 Dephospho-CoA kinase 3 187 1.3E-48 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MCR_0106 57d50f607750b3ec24230151fc963dd4 211 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 200 24.197 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MCR_0106 57d50f607750b3ec24230151fc963dd4 211 SUPERFAMILY SSF52540 1 204 1.36E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0518 d11a298c85368b8b4aebed19f0f1ca68 72 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 33 47 8.8E-14 T 14-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MCR_0518 d11a298c85368b8b4aebed19f0f1ca68 72 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 57 70 8.8E-14 T 14-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MCR_0518 d11a298c85368b8b4aebed19f0f1ca68 72 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 7 23 8.8E-14 T 14-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MCR_0518 d11a298c85368b8b4aebed19f0f1ca68 72 Gene3D G3DSA:3.40.50.150 1 72 7.0E-18 T 14-10-2018 MCR_0518 d11a298c85368b8b4aebed19f0f1ca68 72 SUPERFAMILY SSF53335 1 70 8.31E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0518 d11a298c85368b8b4aebed19f0f1ca68 72 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 7 70 7.8E-19 T 14-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MCR_0908 5470bf92300bb5c242fb2713358229c5 210 Gene3D G3DSA:2.30.30.100 1 80 1.8E-31 T 14-10-2018 MCR_0908 5470bf92300bb5c242fb2713358229c5 210 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 7.4E-29 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MCR_0908 5470bf92300bb5c242fb2713358229c5 210 Pfam PF17209 Hfq protein 7 68 2.9E-30 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MCR_0908 5470bf92300bb5c242fb2713358229c5 210 SUPERFAMILY SSF50182 7 67 5.61E-23 T 14-10-2018 IPR010920 LSM domain superfamily MCR_0908 5470bf92300bb5c242fb2713358229c5 210 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 27.765 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MCR_0200 e238934d80ed69545d53d2518125890e 305 PIRSF PIRSF016660 1 305 5.4E-114 T 14-10-2018 IPR008526 Inner membrane protein YedI MCR_0200 e238934d80ed69545d53d2518125890e 305 Pfam PF05661 Protein of unknown function (DUF808) 5 293 8.2E-110 T 14-10-2018 IPR008526 Inner membrane protein YedI MCR_0523 54b31dfe6eecb02cb3f77951846bea8c 241 Pfam PF10722 Putative bacterial sensory transduction regulator 69 194 2.0E-5 T 14-10-2018 IPR019660 Putative sensory transduction regulator YbjN MCR_0646 070cfb817586ea2746161bf6e9448dbd 99 Gene3D G3DSA:3.30.70.1290 1 99 8.0E-30 T 14-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 MCR_0646 070cfb817586ea2746161bf6e9448dbd 99 SUPERFAMILY SSF143422 3 96 2.22E-30 T 14-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 MCR_0646 070cfb817586ea2746161bf6e9448dbd 99 Pfam PF01797 Transposase IS200 like 3 95 6.8E-29 T 14-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MCR_0646 070cfb817586ea2746161bf6e9448dbd 99 SMART SM01321 1 95 5.0E-22 T 14-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MCR_0849 b58ca2906f87ad3136e56c7024f36914 285 Pfam PF02616 Segregation and condensation protein ScpA 54 253 8.5E-18 T 14-10-2018 IPR003768 Segregation and condensation protein A MCR_0305 fd7a610b3e1588b113327e1360fddfa6 208 Pfam PF09335 SNARE associated Golgi protein 33 162 1.4E-20 T 14-10-2018 IPR032816 SNARE associated Golgi protein MCR_1185 07a8a5ee59f55387c09cfc1a5cddaeb3 620 Pfam PF00999 Sodium/hydrogen exchanger family 13 385 3.8E-45 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MCR_1185 07a8a5ee59f55387c09cfc1a5cddaeb3 620 Gene3D G3DSA:1.20.1530.20 5 394 5.4E-16 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily MCR_1333 682fd653e4af0a28fea1afc22056e400 162 Gene3D G3DSA:3.30.70.990 9 96 5.8E-28 T 14-10-2018 IPR035570 UPF0234, N-terminal MCR_1333 682fd653e4af0a28fea1afc22056e400 162 Gene3D G3DSA:3.30.70.860 97 162 9.9E-27 T 14-10-2018 IPR035571 UPF0234-like, C-terminal MCR_1333 682fd653e4af0a28fea1afc22056e400 162 SUPERFAMILY SSF89963 2 87 1.54E-25 T 14-10-2018 IPR036183 YajQ-like superfamily MCR_1333 682fd653e4af0a28fea1afc22056e400 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 162 24.831 T 14-10-2018 IPR007551 Protein of unknown function DUF520 MCR_1333 682fd653e4af0a28fea1afc22056e400 162 Pfam PF04461 Protein of unknown function (DUF520) 2 161 3.6E-57 T 14-10-2018 IPR007551 Protein of unknown function DUF520 MCR_1333 682fd653e4af0a28fea1afc22056e400 162 SUPERFAMILY SSF89963 90 162 6.93E-25 T 14-10-2018 IPR036183 YajQ-like superfamily MCR_0792 ad58fd1e708b356cd73608dc9de61945 312 PIRSF PIRSF019423 2 312 5.6E-122 T 14-10-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein MCR_0792 ad58fd1e708b356cd73608dc9de61945 312 Gene3D G3DSA:1.10.10.10 224 300 5.4E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0792 ad58fd1e708b356cd73608dc9de61945 312 SUPERFAMILY SSF46785 231 302 1.36E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MCR_0880 67f240fada30409320b047f4bec36c0f 223 Pfam PF02390 Putative methyltransferase 42 180 2.8E-25 T 14-10-2018 MCR_0880 67f240fada30409320b047f4bec36c0f 223 SUPERFAMILY SSF53335 18 179 8.04E-18 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_0880 67f240fada30409320b047f4bec36c0f 223 Gene3D G3DSA:3.40.50.150 12 214 9.4E-35 T 14-10-2018 MCR_0574 30c097e47c6d54e975f9bb68af90e492 214 Pfam PF09829 Uncharacterized protein conserved in bacteria (DUF2057) 23 211 2.3E-33 T 14-10-2018 IPR018635 Uncharacterised protein family UPF0319 MCR_0100 856cbea4f7ba5ea05cc78d169726c0ba 168 Pfam PF13533 Biotin-lipoyl like 60 110 8.8E-13 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MCR_0100 856cbea4f7ba5ea05cc78d169726c0ba 168 SUPERFAMILY SSF111369 52 162 1.7E-18 T 14-10-2018 MCR_0100 856cbea4f7ba5ea05cc78d169726c0ba 168 Gene3D G3DSA:2.40.50.100 60 95 5.0E-26 T 14-10-2018 MCR_0100 856cbea4f7ba5ea05cc78d169726c0ba 168 Gene3D G3DSA:1.10.287.470 96 167 5.0E-26 T 14-10-2018 MCR_0407 f8355acfd7587e7e31729286020a7177 270 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 6 211 3.4E-25 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MCR_0407 f8355acfd7587e7e31729286020a7177 270 SUPERFAMILY SSF51621 5 220 3.84E-48 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MCR_0407 f8355acfd7587e7e31729286020a7177 270 Gene3D G3DSA:3.20.20.60 2 270 3.0E-64 T 14-10-2018 MCR_0407 f8355acfd7587e7e31729286020a7177 270 PIRSF PIRSF015582 2 270 5.8E-62 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like MCR_0911 e9339a310d7a905396136d6293dc9ec1 173 SUPERFAMILY SSF56784 7 167 2.33E-42 T 14-10-2018 IPR036412 HAD-like superfamily MCR_0911 e9339a310d7a905396136d6293dc9ec1 173 PIRSF PIRSF006118 1 173 1.2E-61 T 14-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MCR_0911 e9339a310d7a905396136d6293dc9ec1 173 Pfam PF08282 haloacid dehalogenase-like hydrolase 79 149 3.1E-9 T 14-10-2018 MCR_0911 e9339a310d7a905396136d6293dc9ec1 173 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 11 163 6.2E-50 T 14-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MCR_0911 e9339a310d7a905396136d6293dc9ec1 173 Gene3D G3DSA:3.40.50.1000 4 172 2.2E-55 T 14-10-2018 IPR023214 HAD superfamily MCR_1724 ba37c51f840954804f6363065a31d7e1 305 Gene3D G3DSA:1.10.3720.10 36 304 1.1E-34 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1724 ba37c51f840954804f6363065a31d7e1 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 302 4.5E-6 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_1724 ba37c51f840954804f6363065a31d7e1 305 SUPERFAMILY SSF161098 36 301 4.97E-40 T 14-10-2018 IPR035906 MetI-like superfamily MCR_1304 93634878ab2d3fd9563ed556de8331ba 322 SMART SM00382 46 237 4.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MCR_1304 93634878ab2d3fd9563ed556de8331ba 322 SUPERFAMILY SSF52540 17 259 4.21E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1304 93634878ab2d3fd9563ed556de8331ba 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 271 6.8E-8 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MCR_1304 93634878ab2d3fd9563ed556de8331ba 322 Pfam PF00005 ABC transporter 37 187 1.2E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MCR_1304 93634878ab2d3fd9563ed556de8331ba 322 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MCR_1304 93634878ab2d3fd9563ed556de8331ba 322 Gene3D G3DSA:3.40.50.300 15 320 3.3E-80 T 14-10-2018 MCR_0664 0bf54989ec660e3c2c359c89ae180ce5 88 SUPERFAMILY SSF109910 6 81 5.62E-17 T 14-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily MCR_0664 0bf54989ec660e3c2c359c89ae180ce5 88 Gene3D G3DSA:1.10.150.250 4 87 3.1E-21 T 14-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily MCR_0664 0bf54989ec660e3c2c359c89ae180ce5 88 Pfam PF03937 Flavinator of succinate dehydrogenase 10 79 1.1E-18 T 14-10-2018 IPR005631 Flavinator of succinate dehydrogenase MCR_0095 3ee07ce4602742e1d690392443201366 243 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 47 241 2.1E-75 T 14-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 MCR_0095 3ee07ce4602742e1d690392443201366 243 PIRSF PIRSF000857 14 243 9.0E-73 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MCR_0095 3ee07ce4602742e1d690392443201366 243 Gene3D G3DSA:3.40.50.620 13 243 7.6E-62 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0095 3ee07ce4602742e1d690392443201366 243 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 47 216 2.9E-35 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 MCR_0095 3ee07ce4602742e1d690392443201366 243 SUPERFAMILY SSF52402 20 205 2.09E-35 T 14-10-2018 MCR_1690 d15a56258465cdf6a93632d08f5f9a96 262 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 61 74 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site MCR_1690 d15a56258465cdf6a93632d08f5f9a96 262 SUPERFAMILY SSF53850 6 260 9.19E-60 T 14-10-2018 MCR_1690 d15a56258465cdf6a93632d08f5f9a96 262 Gene3D G3DSA:3.40.190.10 39 257 3.5E-61 T 14-10-2018 MCR_1690 d15a56258465cdf6a93632d08f5f9a96 262 Gene3D G3DSA:3.40.190.10 124 216 3.5E-61 T 14-10-2018 MCR_1690 d15a56258465cdf6a93632d08f5f9a96 262 SMART SM00062 38 260 2.8E-54 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MCR_1690 d15a56258465cdf6a93632d08f5f9a96 262 SMART SM00079 38 259 1.1E-4 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MCR_1690 d15a56258465cdf6a93632d08f5f9a96 262 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 258 1.7E-54 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MCR_0211 32c4518991a895ae9fd7ada0ce197689 112 Gene3D G3DSA:2.30.30.40 40 112 2.9E-32 T 14-10-2018 MCR_0211 32c4518991a895ae9fd7ada0ce197689 112 Pfam PF03831 PhnA domain 42 112 1.3E-32 T 14-10-2018 IPR013988 PhnA protein, C-terminal MCR_0211 32c4518991a895ae9fd7ada0ce197689 112 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 112 5.9E-39 T 14-10-2018 IPR004624 PhnA protein MCR_0211 32c4518991a895ae9fd7ada0ce197689 112 Gene3D G3DSA:2.20.25.10 1 39 5.4E-17 T 14-10-2018 MCR_0211 32c4518991a895ae9fd7ada0ce197689 112 SUPERFAMILY SSF82057 40 112 6.41E-25 T 14-10-2018 MCR_0211 32c4518991a895ae9fd7ada0ce197689 112 SUPERFAMILY SSF57783 1 33 3.57E-12 T 14-10-2018 MCR_0211 32c4518991a895ae9fd7ada0ce197689 112 Pfam PF08274 PhnA Zinc-Ribbon 3 31 5.3E-11 T 14-10-2018 IPR013987 PhnA protein, N-terminal MCR_0765 6bab1cd728e225326488f6ed6e3fcfd8 403 Gene3D G3DSA:1.20.1250.20 1 172 1.0E-40 T 14-10-2018 MCR_0765 6bab1cd728e225326488f6ed6e3fcfd8 403 SUPERFAMILY SSF103473 1 386 1.31E-56 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_0765 6bab1cd728e225326488f6ed6e3fcfd8 403 Pfam PF07690 Major Facilitator Superfamily 3 352 5.2E-37 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MCR_0765 6bab1cd728e225326488f6ed6e3fcfd8 403 Gene3D G3DSA:1.20.1250.20 183 395 5.2E-50 T 14-10-2018 MCR_1596 75526c4e326a5cc5e53c5bf67175c8da 312 Pfam PF01553 Acyltransferase 88 237 8.4E-15 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MCR_1596 75526c4e326a5cc5e53c5bf67175c8da 312 SUPERFAMILY SSF69593 63 297 1.02E-34 T 14-10-2018 MCR_1596 75526c4e326a5cc5e53c5bf67175c8da 312 SMART SM00563 96 238 4.9E-13 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MCR_1540 a3cec76ffc52d323ff55c0b93c187b08 195 Pfam PF04186 FxsA cytoplasmic membrane protein 9 124 1.2E-22 T 14-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 MCR_1273 6bdb325b477a8c70e153cf578cc2a3d9 303 Gene3D G3DSA:2.40.128.270 68 196 1.9E-7 T 14-10-2018 IPR038670 HslJ-like superfamily MCR_1273 6bdb325b477a8c70e153cf578cc2a3d9 303 Pfam PF14302 Domain of unknown function (DUF4377) 212 279 1.5E-8 T 14-10-2018 IPR025485 Domain of unknown function DUF4377 MCR_1273 6bdb325b477a8c70e153cf578cc2a3d9 303 Pfam PF03724 META domain 73 192 5.6E-9 T 14-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ MCR_0775 6ffaf2d0a7c9173844ed391d218b410e 75 Pfam PF15569 Immunity protein 40 7 66 3.3E-8 T 14-10-2018 IPR029080 Immunity protein 40 MCR_0165 343d4eafb73d47f04a1e239d4c298312 191 Pfam PF14803 Nudix N-terminal 2 30 2.3E-13 T 14-10-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 MCR_0165 343d4eafb73d47f04a1e239d4c298312 191 Gene3D G3DSA:3.90.79.10 32 174 4.1E-29 T 14-10-2018 MCR_0165 343d4eafb73d47f04a1e239d4c298312 191 SUPERFAMILY SSF55811 2 158 2.84E-31 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MCR_0165 343d4eafb73d47f04a1e239d4c298312 191 Pfam PF00293 NUDIX domain 39 104 2.3E-9 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MCR_0165 343d4eafb73d47f04a1e239d4c298312 191 Gene3D G3DSA:2.20.70.10 1 31 2.1E-11 T 14-10-2018 MCR_0321 1d6cb28416c2bef951f699408e8db8e2 312 SUPERFAMILY SSF53474 12 310 3.85E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_0321 1d6cb28416c2bef951f699408e8db8e2 312 Pfam PF12146 Serine aminopeptidase, S33 24 294 9.1E-49 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 MCR_0321 1d6cb28416c2bef951f699408e8db8e2 312 Gene3D G3DSA:3.40.50.1820 3 311 6.4E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MCR_1323 d034bfbc6cfe7d838263881fdd2fabb5 493 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 211 266 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1323 d034bfbc6cfe7d838263881fdd2fabb5 493 Gene3D G3DSA:1.20.210.10 11 479 2.3E-196 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1323 d034bfbc6cfe7d838263881fdd2fabb5 493 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 16 468 6.1E-219 T 14-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MCR_1323 d034bfbc6cfe7d838263881fdd2fabb5 493 SUPERFAMILY SSF81442 18 475 3.66E-122 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1323 d034bfbc6cfe7d838263881fdd2fabb5 493 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 21 450 1.5E-111 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_0026 1946a153a16c24e0b188d1855be0410a 1137 SUPERFAMILY SSF52540 448 902 6.61E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0026 1946a153a16c24e0b188d1855be0410a 1137 TIGRFAM TIGR02562 cas3_yersinia: CRISPR-associated helicase Cas3, subtype I-F/YPEST 1 1130 0.0 T 14-10-2018 IPR013395 Helicase Cas3, CRISPR-associated, Yersinia-type MCR_0026 1946a153a16c24e0b188d1855be0410a 1137 Gene3D G3DSA:1.10.3210.30 90 261 2.0E-8 T 14-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily MCR_0209 7fd9283b965bd6876c814ee8264ef9ed 290 Gene3D G3DSA:3.30.465.10 191 282 6.2E-18 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MCR_0209 7fd9283b965bd6876c814ee8264ef9ed 290 Gene3D G3DSA:3.10.580.10 38 190 1.3E-49 T 14-10-2018 MCR_0209 7fd9283b965bd6876c814ee8264ef9ed 290 SUPERFAMILY SSF56176 208 288 3.82E-14 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MCR_0209 7fd9283b965bd6876c814ee8264ef9ed 290 SMART SM00116 135 183 1.8 T 14-10-2018 IPR000644 CBS domain MCR_0209 7fd9283b965bd6876c814ee8264ef9ed 290 SMART SM00116 67 117 0.086 T 14-10-2018 IPR000644 CBS domain MCR_0209 7fd9283b965bd6876c814ee8264ef9ed 290 Pfam PF03471 Transporter associated domain 209 281 1.9E-14 T 14-10-2018 IPR005170 Transporter-associated domain MCR_0209 7fd9283b965bd6876c814ee8264ef9ed 290 SMART SM01091 205 284 2.8E-14 T 14-10-2018 IPR005170 Transporter-associated domain MCR_0209 7fd9283b965bd6876c814ee8264ef9ed 290 SUPERFAMILY SSF54631 48 193 1.11E-32 T 14-10-2018 MCR_0209 7fd9283b965bd6876c814ee8264ef9ed 290 Pfam PF00571 CBS domain 58 116 7.8E-8 T 14-10-2018 IPR000644 CBS domain MCR_0209 7fd9283b965bd6876c814ee8264ef9ed 290 Pfam PF00571 CBS domain 132 183 1.4E-4 T 14-10-2018 IPR000644 CBS domain MCR_1705 d8c5252ca7f800fcbec1331d0c7ed181 138 Pfam PF02677 Uncharacterized BCR, COG1636 2 111 9.7E-36 T 14-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 MCR_0237 cd1cbbf635b5002214daf4f565a3a292 206 Pfam PF02223 Thymidylate kinase 8 199 1.2E-41 T 14-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 MCR_0237 cd1cbbf635b5002214daf4f565a3a292 206 ProSitePatterns PS01331 Thymidylate kinase signature. 92 104 - T 14-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MCR_0237 cd1cbbf635b5002214daf4f565a3a292 206 SUPERFAMILY SSF52540 1 199 4.96E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0237 cd1cbbf635b5002214daf4f565a3a292 206 Gene3D G3DSA:3.40.50.300 1 204 3.6E-57 T 14-10-2018 MCR_0237 cd1cbbf635b5002214daf4f565a3a292 206 Hamap MF_00165 Thymidylate kinase [tmk]. 4 203 25.19 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MCR_0237 cd1cbbf635b5002214daf4f565a3a292 206 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 199 2.4E-45 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MCR_0780 238ebef7b4b6c0d23de31fbe44f5c419 123 SUPERFAMILY SSF160472 9 120 2.09E-13 T 14-10-2018 IPR023138 NMB0513-like superfamily MCR_1292 b2f7c129b8d4a6a260d29b74d187c033 578 Gene3D G3DSA:3.40.720.10 245 575 1.4E-82 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MCR_1292 b2f7c129b8d4a6a260d29b74d187c033 578 SUPERFAMILY SSF53649 263 566 9.45E-18 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MCR_1292 b2f7c129b8d4a6a260d29b74d187c033 578 Pfam PF00884 Sulfatase 266 562 2.8E-38 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MCR_1292 b2f7c129b8d4a6a260d29b74d187c033 578 Pfam PF08019 Domain of unknown function (DUF1705) 87 236 1.4E-40 T 14-10-2018 IPR012549 Phosphoethanolamine transferase, N-terminal GO:0016021 MCR_0463 cb67f32fbdba2a5b53e2137c2fa7a715 419 Pfam PF00144 Beta-lactamase 10 401 6.4E-38 T 14-10-2018 IPR001466 Beta-lactamase-related MCR_0463 cb67f32fbdba2a5b53e2137c2fa7a715 419 SUPERFAMILY SSF56601 17 407 1.27E-55 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MCR_0463 cb67f32fbdba2a5b53e2137c2fa7a715 419 Gene3D G3DSA:3.40.710.30 2 418 9.2E-79 T 14-10-2018 MCR_1322 209628a1ffd0e54a9324d558694f0846 212 Gene3D G3DSA:1.10.760.10 49 212 4.1E-68 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1322 209628a1ffd0e54a9324d558694f0846 212 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 6 189 8.8E-77 T 14-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO MCR_1322 209628a1ffd0e54a9324d558694f0846 212 SUPERFAMILY SSF46626 18 204 2.85E-27 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1322 209628a1ffd0e54a9324d558694f0846 212 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 6 184 7.7E-76 T 14-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO MCR_0956 c9f14589c00a579a86df9941f32c9b6e 150 Pfam PF12869 tRNA_anti-like 1 148 9.3E-23 T 14-10-2018 IPR024422 Protein of unknown function, OB-fold-containing MCR_1375 be082633647251691d6695bbf0e4348a 435 Gene3D G3DSA:3.40.50.11720 38 220 1.9E-32 T 14-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 MCR_1375 be082633647251691d6695bbf0e4348a 435 Gene3D G3DSA:3.40.50.2000 233 418 2.5E-55 T 14-10-2018 MCR_1375 be082633647251691d6695bbf0e4348a 435 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 41 210 1.4E-45 T 14-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 MCR_0365 dcff783a15550c119d6dec44ee66bffc 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 9 20 7.0E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_0365 dcff783a15550c119d6dec44ee66bffc 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 107 120 7.0E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_0365 dcff783a15550c119d6dec44ee66bffc 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 156 176 7.0E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_0365 dcff783a15550c119d6dec44ee66bffc 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 138 154 7.0E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_0365 dcff783a15550c119d6dec44ee66bffc 225 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 12 220 1.4E-63 T 14-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 MCR_0365 dcff783a15550c119d6dec44ee66bffc 225 Gene3D G3DSA:1.10.150.240 24 93 5.2E-61 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MCR_0365 dcff783a15550c119d6dec44ee66bffc 225 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 109 188 7.1E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_0365 dcff783a15550c119d6dec44ee66bffc 225 SUPERFAMILY SSF56784 6 223 1.3E-60 T 14-10-2018 IPR036412 HAD-like superfamily MCR_0365 dcff783a15550c119d6dec44ee66bffc 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 64 193 2.4E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MCR_0365 dcff783a15550c119d6dec44ee66bffc 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 194 2.5E-36 T 14-10-2018 MCR_0365 dcff783a15550c119d6dec44ee66bffc 225 Gene3D G3DSA:3.40.50.1000 12 216 5.2E-61 T 14-10-2018 IPR023214 HAD superfamily MCR_0505 c7d627e0b770beef9ee5c91dbb4261bf 499 Pfam PF01235 Sodium:alanine symporter family 67 480 1.4E-152 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0505 c7d627e0b770beef9ee5c91dbb4261bf 499 TIGRFAM TIGR00835 agcS: amino acid carrier protein 30 469 7.8E-150 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0505 c7d627e0b770beef9ee5c91dbb4261bf 499 PRINTS PR00175 Sodium/alanine symporter signature 237 256 2.0E-55 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0505 c7d627e0b770beef9ee5c91dbb4261bf 499 PRINTS PR00175 Sodium/alanine symporter signature 438 458 2.0E-55 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0505 c7d627e0b770beef9ee5c91dbb4261bf 499 PRINTS PR00175 Sodium/alanine symporter signature 104 126 2.0E-55 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0505 c7d627e0b770beef9ee5c91dbb4261bf 499 PRINTS PR00175 Sodium/alanine symporter signature 332 350 2.0E-55 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0505 c7d627e0b770beef9ee5c91dbb4261bf 499 PRINTS PR00175 Sodium/alanine symporter signature 378 400 2.0E-55 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0505 c7d627e0b770beef9ee5c91dbb4261bf 499 PRINTS PR00175 Sodium/alanine symporter signature 209 227 2.0E-55 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0505 c7d627e0b770beef9ee5c91dbb4261bf 499 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 104 119 - T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MCR_0552 e9a09fa4ae44e1d3cf243e1ef79d710b 534 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 508 4.1E-172 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MCR_0552 e9a09fa4ae44e1d3cf243e1ef79d710b 534 PIRSF PIRSF006446 361 525 3.1E-40 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MCR_0552 e9a09fa4ae44e1d3cf243e1ef79d710b 534 PIRSF PIRSF006446 2 321 9.0E-107 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MCR_1033 76b56455f07f05b996d11aab402e3d2f 386 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 122 375 4.0E-92 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 MCR_1033 76b56455f07f05b996d11aab402e3d2f 386 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 29 378 1.9E-98 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 MCR_1033 76b56455f07f05b996d11aab402e3d2f 386 SUPERFAMILY SSF53659 27 379 1.31E-83 T 14-10-2018 MCR_1033 76b56455f07f05b996d11aab402e3d2f 386 Gene3D G3DSA:3.40.718.10 15 381 9.0E-103 T 14-10-2018 MCR_0560 1c8479040951ebd02d6aa62bdedfef70 355 Pfam PF04536 TPM domain 107 230 2.2E-36 T 14-10-2018 IPR007621 TPM domain MCR_0560 1c8479040951ebd02d6aa62bdedfef70 355 Gene3D G3DSA:3.10.310.50 92 239 6.8E-42 T 14-10-2018 MCR_1257 393039dc5cc23e7965b2dac763de7e4e 238 Pfam PF04172 LrgB-like family 24 234 2.9E-60 T 14-10-2018 IPR007300 CidB/LrgB family MCR_0717 f4508e5fc81a16bcce210cd18760efde 210 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 28 171 4.4E-30 T 14-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MCR_0717 f4508e5fc81a16bcce210cd18760efde 210 Gene3D G3DSA:1.20.120.1200 14 173 1.1E-40 T 14-10-2018 MCR_0452 e60c866583dc1c43addbedb8ca3cab69 462 Gene3D G3DSA:1.20.1740.10 11 455 3.9E-68 T 14-10-2018 MCR_0452 e60c866583dc1c43addbedb8ca3cab69 462 Pfam PF00324 Amino acid permease 20 408 1.4E-34 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MCR_0452 e60c866583dc1c43addbedb8ca3cab69 462 PIRSF PIRSF006060 2 461 9.9E-65 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MCR_1087 15b0781e670039f1be2f12e467acb617 320 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 152 318 1.0E-53 T 14-10-2018 IPR005642 Lysine exporter LysO MCR_1087 15b0781e670039f1be2f12e467acb617 320 Pfam PF03956 Lysine exporter LysO 131 316 2.5E-46 T 14-10-2018 IPR005642 Lysine exporter LysO MCR_0309 fc33bf539eb744b16be75923f41e4bb3 314 SMART SM00481 18 83 1.2E-17 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MCR_0309 fc33bf539eb744b16be75923f41e4bb3 314 Gene3D G3DSA:1.10.150.650 121 204 2.3E-68 T 14-10-2018 MCR_0309 fc33bf539eb744b16be75923f41e4bb3 314 Pfam PF02811 PHP domain 19 141 1.0E-8 T 14-10-2018 IPR004013 PHP domain GO:0003824 MCR_0309 fc33bf539eb744b16be75923f41e4bb3 314 SUPERFAMILY SSF89550 15 291 3.01E-43 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MCR_0309 fc33bf539eb744b16be75923f41e4bb3 314 Gene3D G3DSA:3.20.20.140 18 284 2.3E-68 T 14-10-2018 MCR_1673 c9477ceeec8df57a38d6f9b69c5c6f4b 238 SMART SM00507 158 210 3.3E-9 T 14-10-2018 IPR003615 HNH nuclease MCR_1123 7e6518da1aa0372ab6b7857c0f4d5b21 99 Gene3D G3DSA:1.10.3290.10 1 98 4.1E-5 T 14-10-2018 IPR036597 Fido-like domain superfamily MCR_1213 14170c8cdf00c8aa83ce4e4ca119588a 348 Gene3D G3DSA:1.20.1250.20 160 345 1.3E-9 T 14-10-2018 MCR_1213 14170c8cdf00c8aa83ce4e4ca119588a 348 Gene3D G3DSA:1.20.1250.20 1 140 1.7E-9 T 14-10-2018 MCR_1213 14170c8cdf00c8aa83ce4e4ca119588a 348 Pfam PF07690 Major Facilitator Superfamily 17 278 1.8E-16 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MCR_1213 14170c8cdf00c8aa83ce4e4ca119588a 348 SUPERFAMILY SSF103473 10 337 2.09E-18 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_0582 d893656d5c2d6a75cc1e42c3ec4df4f8 115 Pfam PF08888 HopJ type III effector protein 14 111 3.2E-38 T 14-10-2018 IPR014984 HopJ type III effector protein MCR_0582 d893656d5c2d6a75cc1e42c3ec4df4f8 115 Gene3D G3DSA:3.20.160.10 1 114 3.1E-40 T 14-10-2018 IPR038604 Type III effector HopJ superfamily MCR_1053 0263cbe8193f25001cc803de7eaef977 356 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 7 253 1.5E-67 T 14-10-2018 IPR017689 Outer membrane protein assembly factor BamD MCR_1053 0263cbe8193f25001cc803de7eaef977 356 Pfam PF13525 Outer membrane lipoprotein 39 245 3.4E-55 T 14-10-2018 IPR039565 Outer membrane lipoprotein BamD-like MCR_1053 0263cbe8193f25001cc803de7eaef977 356 SUPERFAMILY SSF48452 40 117 4.05E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_1053 0263cbe8193f25001cc803de7eaef977 356 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 6 251 28.864 T 14-10-2018 IPR017689 Outer membrane protein assembly factor BamD MCR_1053 0263cbe8193f25001cc803de7eaef977 356 Gene3D G3DSA:1.25.40.10 40 260 8.1E-47 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0997 97620ddf326f6792375b46e5bc5eddee 292 SUPERFAMILY SSF161098 22 279 5.36E-50 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0997 97620ddf326f6792375b46e5bc5eddee 292 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 15 283 6.7E-104 T 14-10-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 MCR_0997 97620ddf326f6792375b46e5bc5eddee 292 Gene3D G3DSA:1.10.3720.10 21 285 1.0E-59 T 14-10-2018 IPR035906 MetI-like superfamily MCR_0997 97620ddf326f6792375b46e5bc5eddee 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 280 1.7E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MCR_0997 97620ddf326f6792375b46e5bc5eddee 292 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 14 281 1.4E-82 T 14-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 MCR_1347 b7ad83e5d0c5fee30f11dc60c144a1e5 153 Gene3D G3DSA:1.20.120.520 1 144 2.6E-11 T 14-10-2018 MCR_1347 b7ad83e5d0c5fee30f11dc60c144a1e5 153 Pfam PF01814 Hemerythrin HHE cation binding domain 6 121 7.0E-15 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MCR_0649 392694ceb190e8cc9c049c9b33bc11e8 169 Pfam PF04170 NlpE N-terminal domain 71 141 1.8E-19 T 14-10-2018 IPR007298 Copper resistance lipoprotein NlpE MCR_0649 392694ceb190e8cc9c049c9b33bc11e8 169 Gene3D G3DSA:2.40.128.300 45 145 3.5E-19 T 14-10-2018 MCR_0471 7e597b6434ffaccb92f7852e4b355016 144 PRINTS PR00332 Histidine triad family signature 98 108 1.8E-17 T 14-10-2018 IPR001310 Histidine triad (HIT) protein MCR_0471 7e597b6434ffaccb92f7852e4b355016 144 PRINTS PR00332 Histidine triad family signature 10 26 1.8E-17 T 14-10-2018 IPR001310 Histidine triad (HIT) protein MCR_0471 7e597b6434ffaccb92f7852e4b355016 144 PRINTS PR00332 Histidine triad family signature 31 49 1.8E-17 T 14-10-2018 IPR001310 Histidine triad (HIT) protein MCR_0471 7e597b6434ffaccb92f7852e4b355016 144 Gene3D G3DSA:3.30.428.10 3 143 1.0E-34 T 14-10-2018 IPR036265 HIT-like superfamily MCR_0471 7e597b6434ffaccb92f7852e4b355016 144 Pfam PF01230 HIT domain 16 111 4.1E-23 T 14-10-2018 IPR001310 Histidine triad (HIT) protein MCR_0471 7e597b6434ffaccb92f7852e4b355016 144 SUPERFAMILY SSF54197 4 142 2.32E-35 T 14-10-2018 IPR036265 HIT-like superfamily MCR_0870 71ff60bf151544bc3881de579334d0ec 133 Pfam PF06305 Lipopolysaccharide assembly protein A domain 23 87 4.4E-14 T 14-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 MCR_0870 71ff60bf151544bc3881de579334d0ec 133 ProDom PD113178 RIBOSOMAL MRP8 YKL142W CEREVISIAE MITOCHONDRIAL SACCHAROMYCES P35719 HANSENII DEBARYOMYCES STRAIN 72 120 0.004 T 14-10-2018 IPR012917 Protein of unknown function DUF3294 MCR_0374 198d160e2aa92690bfcea992d000fddb 132 Pfam PF03899 ATP synthase I chain 22 118 4.2E-13 T 14-10-2018 IPR005598 ATP synthase protein I MCR_0415 93939781d7e20e63311c18d0fd99f1a1 318 Gene3D G3DSA:3.60.21.10 1 308 1.9E-32 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like MCR_0415 93939781d7e20e63311c18d0fd99f1a1 318 Pfam PF00149 Calcineurin-like phosphoesterase 5 95 1.9E-9 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MCR_0415 93939781d7e20e63311c18d0fd99f1a1 318 SUPERFAMILY SSF56300 4 291 8.63E-23 T 14-10-2018 MCR_1470 ff3e9d162a2fbe50d09828ffde43c53e 162 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 137 1.9E-12 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MCR_1470 ff3e9d162a2fbe50d09828ffde43c53e 162 Gene3D G3DSA:2.40.10.330 71 122 3.1E-59 T 14-10-2018 MCR_1470 ff3e9d162a2fbe50d09828ffde43c53e 162 SUPERFAMILY SSF54534 4 141 4.12E-37 T 14-10-2018 MCR_1470 ff3e9d162a2fbe50d09828ffde43c53e 162 Gene3D G3DSA:3.10.50.40 4 155 3.1E-59 T 14-10-2018 MCR_1672 fe29ce6b8a24ae8d78b38017921cb278 509 Pfam PF03929 PepSY-associated TM region 26 436 1.3E-59 T 14-10-2018 IPR005625 PepSY-associated TM protein MCR_1398 2e541db36d6c86f4ac6ea271b749db8f 97 SUPERFAMILY SSF46626 21 96 6.6E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1398 2e541db36d6c86f4ac6ea271b749db8f 97 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 19 95 3.1E-15 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MCR_1398 2e541db36d6c86f4ac6ea271b749db8f 97 Gene3D G3DSA:1.10.760.10 19 97 1.6E-23 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MCR_1398 2e541db36d6c86f4ac6ea271b749db8f 97 PRINTS PR00607 Class IE cytochrome C signature 41 51 6.3E-9 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MCR_1398 2e541db36d6c86f4ac6ea271b749db8f 97 PRINTS PR00607 Class IE cytochrome C signature 30 41 6.3E-9 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MCR_1398 2e541db36d6c86f4ac6ea271b749db8f 97 PRINTS PR00607 Class IE cytochrome C signature 70 82 6.3E-9 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MCR_1398 2e541db36d6c86f4ac6ea271b749db8f 97 PRINTS PR00607 Class IE cytochrome C signature 85 96 6.3E-9 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MCR_1221 76e8a357bacee630f65fdf6cfa08b9b1 173 Pfam PF13302 Acetyltransferase (GNAT) domain 71 152 2.8E-12 T 14-10-2018 IPR000182 GNAT domain MCR_1221 76e8a357bacee630f65fdf6cfa08b9b1 173 Gene3D G3DSA:3.40.630.30 39 154 1.4E-22 T 14-10-2018 MCR_1221 76e8a357bacee630f65fdf6cfa08b9b1 173 SUPERFAMILY SSF55729 5 159 7.62E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MCR_0203 69cca609a389f4698c63590ff74d50f7 78 Pfam PF10981 Protein of unknown function (DUF2788) 24 72 1.1E-18 T 14-10-2018 IPR021249 Protein of unknown function DUF2788 MCR_0882 33ea8377088e704a6558cc7789866744 455 Pfam PF03109 ABC1 family 125 230 4.5E-28 T 14-10-2018 IPR004147 UbiB domain MCR_0882 33ea8377088e704a6558cc7789866744 455 SUPERFAMILY SSF56112 101 310 2.01E-12 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MCR_1372 b12805ca389286d344190e80c582752a 365 Pfam PF04311 Protein of unknown function (DUF459) 133 352 3.6E-21 T 14-10-2018 IPR007407 Protein of unknown function DUF459 MCR_1372 b12805ca389286d344190e80c582752a 365 Gene3D G3DSA:3.40.50.1110 155 362 3.0E-24 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MCR_1372 b12805ca389286d344190e80c582752a 365 SUPERFAMILY SSF52266 157 361 3.51E-27 T 14-10-2018 MCR_1815 ac8f88f9c658838f314de78e135cc301 396 Pfam PF03739 Predicted permease YjgP/YjgQ family 19 376 1.2E-97 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 MCR_1815 ac8f88f9c658838f314de78e135cc301 396 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 16 378 6.1E-91 T 14-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 MCR_1252 e0cd9497c69cf694b337127753e2a778 97 TIGRFAM TIGR02610 PHA_gran_rgn: putative polyhydroxyalkanoic acid system protein 1 92 6.1E-11 T 14-10-2018 IPR013433 Putative polyhydroxyalkanoic acid system protein MCR_1252 e0cd9497c69cf694b337127753e2a778 97 Pfam PF09650 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) 4 93 1.5E-22 T 14-10-2018 IPR013433 Putative polyhydroxyalkanoic acid system protein MCR_1229 7d06d2d0093d0da5912f62d562c3ec84 443 Pfam PF07690 Major Facilitator Superfamily 17 388 7.8E-18 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MCR_1229 7d06d2d0093d0da5912f62d562c3ec84 443 Gene3D G3DSA:1.20.1250.20 6 427 1.3E-27 T 14-10-2018 MCR_1229 7d06d2d0093d0da5912f62d562c3ec84 443 SUPERFAMILY SSF103473 6 426 5.36E-29 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_1850 cac21326cbd928a535e02a4ee30156a9 158 Pfam PF03652 Holliday junction resolvase 7 140 2.3E-32 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MCR_1850 cac21326cbd928a535e02a4ee30156a9 158 SMART SM00732 5 110 1.1E-21 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MCR_1850 cac21326cbd928a535e02a4ee30156a9 158 Gene3D G3DSA:3.30.420.140 4 142 9.4E-33 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 MCR_1850 cac21326cbd928a535e02a4ee30156a9 158 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 5 144 20.188 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MCR_1850 cac21326cbd928a535e02a4ee30156a9 158 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 8 140 3.0E-30 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MCR_1850 cac21326cbd928a535e02a4ee30156a9 158 SUPERFAMILY SSF53098 6 141 1.52E-30 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MCR_0937 5035f6248ff40f6ce8bcdd3cb5ed9081 298 Pfam PF14337 Domain of unknown function (DUF4393) 70 294 5.1E-64 T 14-10-2018 IPR025506 Protein of unknown function DUF4393 MCR_1665 7975e752e71cac30be5c3174622eeb8a 216 Pfam PF01810 LysE type translocator 16 214 3.0E-38 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MCR_1665 7975e752e71cac30be5c3174622eeb8a 216 PIRSF PIRSF006324 1 216 4.5E-48 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MCR_1789 2350f15c3520b36f6d07d0ce06f5ddb4 445 Pfam PF07510 Protein of unknown function (DUF1524) 272 407 7.6E-18 T 14-10-2018 IPR011089 Domain of unknown function DUF1524 MCR_1646 1acdd70b1bc240135aecdc6b9c7d18e5 351 SUPERFAMILY SSF52540 164 339 7.64E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1646 1acdd70b1bc240135aecdc6b9c7d18e5 351 Pfam PF13521 AAA domain 168 329 1.7E-31 T 14-10-2018 IPR038727 NadR/Ttd14, AAA domain MCR_1646 1acdd70b1bc240135aecdc6b9c7d18e5 351 Gene3D G3DSA:3.40.50.300 165 334 3.9E-50 T 14-10-2018 MCR_0225 64576841c8d3be959e9a7ca20b71226d 709 Pfam PF12787 EcsC protein family 461 682 1.2E-10 T 14-10-2018 IPR024787 EcsC protein MCR_0225 64576841c8d3be959e9a7ca20b71226d 709 Gene3D G3DSA:1.20.120.20 2 205 1.6E-5 T 14-10-2018 MCR_0225 64576841c8d3be959e9a7ca20b71226d 709 Gene3D G3DSA:1.20.120.20 206 346 5.3E-9 T 14-10-2018 MCR_0225 64576841c8d3be959e9a7ca20b71226d 709 SUPERFAMILY SSF58113 159 284 9.81E-6 T 14-10-2018 MCR_0059 5defa73889b2b7f5ad268e7ea8dbccb1 334 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 183 6.6E-43 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MCR_0059 5defa73889b2b7f5ad268e7ea8dbccb1 334 Gene3D G3DSA:3.40.50.300 4 200 3.4E-49 T 14-10-2018 MCR_0059 5defa73889b2b7f5ad268e7ea8dbccb1 334 SUPERFAMILY SSF52540 6 202 2.01E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_0698 92f84a6fe2e149292b41d65806cfce9c 259 Pfam PF02517 CAAX protease self-immunity 154 250 4.1E-15 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MCR_0520 3fa989a66ceef822b501942456f6b02c 56 Pfam PF14207 DpnD/PcfM-like protein 4 49 3.2E-20 T 14-10-2018 IPR025575 DpnD/PcfM-like protein MCR_1131 594227e3de02274d4992885da5eb6507 125 Pfam PF06073 Bacterial protein of unknown function (DUF934) 23 124 6.9E-19 T 14-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 MCR_1531 de91145d93778c6eea56f9bb7f68a955 348 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 136 152 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site MCR_1531 de91145d93778c6eea56f9bb7f68a955 348 Gene3D G3DSA:1.10.600.10 35 341 2.6E-83 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MCR_1531 de91145d93778c6eea56f9bb7f68a955 348 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 268 280 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site MCR_1531 de91145d93778c6eea56f9bb7f68a955 348 SUPERFAMILY SSF48576 55 339 9.0E-77 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MCR_1531 de91145d93778c6eea56f9bb7f68a955 348 Pfam PF00348 Polyprenyl synthetase 76 319 3.3E-56 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 MCR_0085 842eb3e4296ad87d35a55645332b6483 249 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 8 237 1.8E-14 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MCR_0085 842eb3e4296ad87d35a55645332b6483 249 Gene3D G3DSA:3.60.10.10 2 246 3.3E-39 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MCR_0085 842eb3e4296ad87d35a55645332b6483 249 SUPERFAMILY SSF56219 3 244 6.02E-39 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MCR_0514 28a0b8881cec3c883feb5dafbcfd683f 615 Pfam PF13387 Domain of unknown function (DUF4105) 158 323 7.5E-40 T 14-10-2018 IPR025178 Domain of unknown function DUF4105 MCR_0399 6261d83826ca7efff762da85c6833b29 305 SUPERFAMILY SSF103481 56 153 4.97E-11 T 14-10-2018 MCR_0399 6261d83826ca7efff762da85c6833b29 305 Pfam PF00892 EamA-like transporter family 22 153 8.3E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MCR_0399 6261d83826ca7efff762da85c6833b29 305 Pfam PF00892 EamA-like transporter family 165 296 2.4E-9 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MCR_0013 e2affe75af00bc48a844c4bbed407fac 117 SUPERFAMILY SSF55298 13 116 3.3E-28 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MCR_0013 e2affe75af00bc48a844c4bbed407fac 117 Pfam PF01042 Endoribonuclease L-PSP 8 115 8.6E-24 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MCR_0013 e2affe75af00bc48a844c4bbed407fac 117 Gene3D G3DSA:3.30.1330.40 1 117 3.8E-36 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MCR_1717 85805cdea5ea61fc29e74b04d7f69673 340 Pfam PF13303 Phosphotransferase system, EIIC 24 336 1.2E-105 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MCR_0110 5e5b83cff16088ec0aa5783ea9926e8b 407 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 15 396 8.1E-78 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 MCR_0110 5e5b83cff16088ec0aa5783ea9926e8b 407 SUPERFAMILY SSF103473 9 399 2.22E-54 T 14-10-2018 IPR036259 MFS transporter superfamily MCR_0110 5e5b83cff16088ec0aa5783ea9926e8b 407 Pfam PF07690 Major Facilitator Superfamily 22 364 2.4E-35 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MCR_0110 5e5b83cff16088ec0aa5783ea9926e8b 407 Gene3D G3DSA:1.20.1720.10 15 397 6.8E-92 T 14-10-2018 MCR_1848 0d046e10631987a05b7cb29a2f337905 79 Pfam PF01206 Sulfurtransferase TusA 6 76 9.3E-26 T 14-10-2018 IPR001455 TusA-like domain MCR_1848 0d046e10631987a05b7cb29a2f337905 79 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 8 32 - T 14-10-2018 IPR001455 TusA-like domain MCR_1848 0d046e10631987a05b7cb29a2f337905 79 SUPERFAMILY SSF64307 3 76 1.07E-23 T 14-10-2018 IPR036868 TusA-like domain superfamily MCR_1848 0d046e10631987a05b7cb29a2f337905 79 Gene3D G3DSA:3.30.110.40 1 77 8.2E-26 T 14-10-2018 IPR036868 TusA-like domain superfamily MCR_1420 03212331345d79608eb529bef81e03d3 395 Pfam PF05940 NnrS protein 12 389 2.1E-99 T 14-10-2018 IPR010266 NnrS MCR_0208 03199a2e647b649df26e6d0c77964d72 154 Pfam PF03692 Putative zinc- or iron-chelating domain 28 97 1.6E-6 T 14-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein MCR_0208 03199a2e647b649df26e6d0c77964d72 154 PIRSF PIRSF006173 2 153 4.5E-50 T 14-10-2018 IPR008228 Uncharacterised conserved protein UCP006173 MCR_0979 cbd0ed43a020a5a34cc5cfccd03776b7 264 SUPERFAMILY SSF74653 175 232 3.14E-6 T 14-10-2018 MCR_0979 cbd0ed43a020a5a34cc5cfccd03776b7 264 Gene3D G3DSA:3.30.1150.10 143 258 1.1E-9 T 14-10-2018 MCR_0851 5f9114cf43e8a5ec58ae0b0de17dadc8 274 Gene3D G3DSA:3.20.20.70 2 274 1.8E-92 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MCR_0851 5f9114cf43e8a5ec58ae0b0de17dadc8 274 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 7 272 32.566 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MCR_0851 5f9114cf43e8a5ec58ae0b0de17dadc8 274 Pfam PF00218 Indole-3-glycerol phosphate synthase 9 268 1.3E-84 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MCR_0851 5f9114cf43e8a5ec58ae0b0de17dadc8 274 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 59 77 - T 14-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 MCR_0851 5f9114cf43e8a5ec58ae0b0de17dadc8 274 SUPERFAMILY SSF51366 4 271 7.3E-79 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MCR_0331 2dd315feba80c639c9b5ed6f02ca0dc1 214 Pfam PF09335 SNARE associated Golgi protein 49 174 1.4E-21 T 14-10-2018 IPR032816 SNARE associated Golgi protein MCR_0726 d0d1ccb86f17ee6e14cbe28d60383dca 235 Gene3D G3DSA:3.40.50.620 31 175 1.1E-7 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MCR_0726 d0d1ccb86f17ee6e14cbe28d60383dca 235 Pfam PF02698 DUF218 domain 54 201 8.9E-22 T 14-10-2018 IPR003848 Domain of unknown function DUF218 MCR_1093 00974b2736adb6669d97a7a601675e1b 534 Gene3D G3DSA:3.90.550.10 265 432 3.3E-25 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1093 00974b2736adb6669d97a7a601675e1b 534 Gene3D G3DSA:3.90.550.10 1 164 7.1E-22 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1093 00974b2736adb6669d97a7a601675e1b 534 SUPERFAMILY SSF53448 6 149 1.21E-24 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1093 00974b2736adb6669d97a7a601675e1b 534 SUPERFAMILY SSF53448 279 424 1.78E-25 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MCR_1093 00974b2736adb6669d97a7a601675e1b 534 Pfam PF00535 Glycosyl transferase family 2 284 398 2.4E-17 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MCR_1093 00974b2736adb6669d97a7a601675e1b 534 Pfam PF00535 Glycosyl transferase family 2 10 129 2.6E-16 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MCR_1094 82cd09c047f22b07436074163dc6d9be 254 Pfam PF01755 Glycosyltransferase family 25 (LPS biosynthesis protein) 1 180 1.8E-43 T 14-10-2018 IPR002654 Glycosyl transferase, family 25 MCR_1011 1d97b5d973131b58e36924f8a6bac558 464 Pfam PF03553 Na+/H+ antiporter family 161 453 6.1E-38 T 14-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MCR_1214 6d7be48edd71faec48472143243ac5bb 375 SUPERFAMILY SSF51197 51 211 1.19E-8 T 14-10-2018 MCR_1214 6d7be48edd71faec48472143243ac5bb 375 Gene3D G3DSA:2.60.120.650 4 203 3.6E-6 T 14-10-2018 MCR_1192 c03b1e410c61f1bf2c3f54b209e84f82 55 SUPERFAMILY SSF47598 5 48 6.18E-7 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MCR_1735 e907345df4f97a2647bbf33ff21bc1da 275 Pfam PF01435 Peptidase family M48 77 260 9.0E-36 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MCR_0629 425b5cf9cf1ddbe9cb0474990f408608 322 Gene3D G3DSA:2.60.200.30 145 289 4.3E-85 T 14-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MCR_0629 425b5cf9cf1ddbe9cb0474990f408608 322 Pfam PF01513 ATP-NAD kinase 17 292 2.9E-61 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MCR_0629 425b5cf9cf1ddbe9cb0474990f408608 322 Gene3D G3DSA:3.40.50.10330 33 312 4.3E-85 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MCR_0629 425b5cf9cf1ddbe9cb0474990f408608 322 Hamap MF_00361 NAD kinase [nadK]. 15 312 31.513 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MCR_0629 425b5cf9cf1ddbe9cb0474990f408608 322 SUPERFAMILY SSF111331 16 314 1.57E-80 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MCR_0987 a5855a3f472846a4a2bf739f95510df6 65 SUPERFAMILY SSF47598 25 63 3.48E-5 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MCR_0117 532ccb16d4fb2359da8fd3ce757f810b 192 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 91 126 0.0011 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MCR_0534 237dc315f41d3f510ea60eeb4a4d76ae 217 Pfam PF14317 YcxB-like protein 149 187 3.0E-6 T 14-10-2018 IPR025588 YcxB-like protein MCR_0993 c23881c9f9ade8b4c71b5775640153c7 46 Pfam PF08085 Entericidin EcnA/B family 21 39 1.3E-8 T 14-10-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 MCR_0975 18aea4cd0d9f33e148fe616abf17b0bf 498 Pfam PF02321 Outer membrane efflux protein 53 285 3.8E-16 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MCR_0975 18aea4cd0d9f33e148fe616abf17b0bf 498 Pfam PF02321 Outer membrane efflux protein 320 478 2.3E-17 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MCR_0975 18aea4cd0d9f33e148fe616abf17b0bf 498 SUPERFAMILY SSF56954 26 484 1.31E-48 T 14-10-2018 MCR_1483 e1826b47946574110f1f1b6c0e55abf0 48 Pfam PF13627 Prokaryotic lipoprotein-attachment site 8 29 2.3E-8 T 14-10-2018 IPR032831 Prokaryotic lipoprotein-attachment site MCR_0522 0148b1c67c8308ac8851e1a51f1bbdfe 301 Pfam PF00850 Histone deacetylase domain 26 280 1.5E-45 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MCR_0522 0148b1c67c8308ac8851e1a51f1bbdfe 301 PRINTS PR01270 Histone deacetylase superfamily signature 224 234 1.7E-12 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MCR_0522 0148b1c67c8308ac8851e1a51f1bbdfe 301 PRINTS PR01270 Histone deacetylase superfamily signature 150 165 1.7E-12 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MCR_0522 0148b1c67c8308ac8851e1a51f1bbdfe 301 PRINTS PR01270 Histone deacetylase superfamily signature 116 139 1.7E-12 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MCR_0522 0148b1c67c8308ac8851e1a51f1bbdfe 301 SUPERFAMILY SSF52768 4 288 4.51E-74 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily MCR_0522 0148b1c67c8308ac8851e1a51f1bbdfe 301 Gene3D G3DSA:3.40.800.20 5 299 1.2E-61 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MCR_1402 afdc0deef66d04a1898b6d8133c2fd57 462 SUPERFAMILY SSF52777 231 424 3.56E-5 T 14-10-2018 MCR_1402 afdc0deef66d04a1898b6d8133c2fd57 462 SUPERFAMILY SSF52777 77 153 4.11E-5 T 14-10-2018 MCR_1402 afdc0deef66d04a1898b6d8133c2fd57 462 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 453 2.0E-107 T 14-10-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MCR_1402 afdc0deef66d04a1898b6d8133c2fd57 462 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 268 5.2E-40 T 14-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MCR_1402 afdc0deef66d04a1898b6d8133c2fd57 462 Pfam PF06974 Protein of unknown function (DUF1298) 308 451 8.6E-30 T 14-10-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MCR_1117 e99c58f2f9539cc20bad53a9fe455e5f 115 PIRSF PIRSF005610 1 111 1.3E-7 T 14-10-2018 IPR007360 Invasion gene expression up-regulator, SirB MCR_1117 e99c58f2f9539cc20bad53a9fe455e5f 115 Pfam PF04247 Invasion gene expression up-regulator, SirB 1 112 2.6E-21 T 14-10-2018 IPR007360 Invasion gene expression up-regulator, SirB MCR_0339 487d6354603c806dd92a6439e9478acd 115 SUPERFAMILY SSF102829 22 110 3.79E-11 T 14-10-2018 IPR036192 Cell division protein ZapA-like superfamily MCR_0339 487d6354603c806dd92a6439e9478acd 115 Pfam PF05164 Cell division protein ZapA 22 110 5.0E-14 T 14-10-2018 IPR007838 Cell division protein ZapA-like MCR_0339 487d6354603c806dd92a6439e9478acd 115 Gene3D G3DSA:1.10.20.30 17 65 2.9E-5 T 14-10-2018 MCR_0774 1172e1225fadcb807daf774ff4b0a774 211 Pfam PF04829 Pre-toxin domain with VENN motif 11 55 1.4E-7 T 14-10-2018 IPR006914 VENN motif-containing domain MCR_0310 0a75aadf68c08dd3899dce8658390425 298 Gene3D G3DSA:1.10.10.10 243 283 3.6E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0310 0a75aadf68c08dd3899dce8658390425 298 Gene3D G3DSA:1.10.10.10 134 175 1.2E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MCR_0310 0a75aadf68c08dd3899dce8658390425 298 Pfam PF02631 RecX family 152 289 1.6E-17 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 MCR_0920 efcba96f356b7367066fe16bbf85ef4a 707 Pfam PF05787 Bacterial protein of unknown function (DUF839) 72 666 2.7E-135 T 14-10-2018 IPR008557 Protein of unknown function DUF839 MCR_0920 efcba96f356b7367066fe16bbf85ef4a 707 SUPERFAMILY SSF101898 428 659 3.14E-7 T 14-10-2018 MCR_1628 cd7f59edeb9e453915fea8d748ad90bf 665 Pfam PF13148 Protein of unknown function (DUF3987) 230 577 1.2E-40 T 14-10-2018 IPR025048 Protein of unknown function DUF3987) MCR_0750 9c61f6f301014e8f744f09c9073ea9bf 307 SUPERFAMILY SSF54534 143 253 7.85E-23 T 14-10-2018 MCR_0750 9c61f6f301014e8f744f09c9073ea9bf 307 Gene3D G3DSA:1.10.4030.30 51 261 8.9E-30 T 14-10-2018 MCR_0750 9c61f6f301014e8f744f09c9073ea9bf 307 Pfam PF13616 PPIC-type PPIASE domain 149 251 6.0E-21 T 14-10-2018 MCR_0750 9c61f6f301014e8f744f09c9073ea9bf 307 Gene3D G3DSA:3.10.50.40 147 252 8.9E-30 T 14-10-2018 MCR_0950 35cb4dcc9ff530b99aaa4ebf1b896f7c 127 Pfam PF13554 Bacteriophage related domain of unknown function 6 124 6.8E-12 T 14-10-2018 IPR025395 Protein of unknown function DUF4128 MCR_0950 35cb4dcc9ff530b99aaa4ebf1b896f7c 127 Gene3D G3DSA:3.30.2000.20 1 127 2.9E-9 T 14-10-2018 MCR_1644 37a63038872072c4d37ace9c3fc448f2 85 Pfam PF04024 PspC domain 10 68 7.6E-22 T 14-10-2018 IPR007168 Phage shock protein, PspC, N-terminal MCR_1371 6ed6edced348612a58359908220e1977 487 PIRSF PIRSF016636 1 487 2.6E-112 T 14-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB MCR_1371 6ed6edced348612a58359908220e1977 487 PIRSF PIRSF500217 1 487 1.2E-112 T 14-10-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 MCR_1371 6ed6edced348612a58359908220e1977 487 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 138 384 3.9E-17 T 14-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT MCR_0960 7848b92eab5019750ab1689a63bb0fbe 1328 Pfam PF10145 Phage-related minor tail protein 140 339 1.7E-33 T 14-10-2018 IPR010090 Phage tail tape measure protein MCR_0960 7848b92eab5019750ab1689a63bb0fbe 1328 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 96 447 5.3E-65 T 14-10-2018 IPR010090 Phage tail tape measure protein MCR_1679 25e3c22fdc79d38ea0faa77105a50183 281 SUPERFAMILY SSF53335 14 261 6.93E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MCR_1679 25e3c22fdc79d38ea0faa77105a50183 281 Gene3D G3DSA:3.40.50.150 14 280 3.8E-62 T 14-10-2018 MCR_1679 25e3c22fdc79d38ea0faa77105a50183 281 Pfam PF08241 Methyltransferase domain 99 185 1.3E-11 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MCR_1679 25e3c22fdc79d38ea0faa77105a50183 281 PIRSF PIRSF018249 10 279 1.2E-72 T 14-10-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 MCR_0412 7897f732908a24f697a9f82b3b3887ed 152 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 148 3.5E-41 T 14-10-2018 IPR003791 Protein of unknown function UPF0178 MCR_0412 7897f732908a24f697a9f82b3b3887ed 152 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 151 28.617 T 14-10-2018 IPR003791 Protein of unknown function UPF0178 MCR_1109 a1e26e6b6a82d758460c126799c7c989 272 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 20 250 3.1E-43 T 14-10-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 MCR_1452 6d8abaefb85dc8c80e1d3b8faed31ea4 437 SUPERFAMILY SSF52540 307 434 1.75E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MCR_1452 6d8abaefb85dc8c80e1d3b8faed31ea4 437 Gene3D G3DSA:3.40.50.300 309 437 3.3E-6 T 14-10-2018 MCR_1042 fd938b10e8bbd6bc69c7556f6e5139d1 134 Pfam PF14302 Domain of unknown function (DUF4377) 49 129 3.3E-18 T 14-10-2018 IPR025485 Domain of unknown function DUF4377 MCR_1234 d11420e983579ad08be3d5a7c4a41ef8 420 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 8 113 1.2E-17 T 14-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI MCR_1234 d11420e983579ad08be3d5a7c4a41ef8 420 Gene3D G3DSA:1.25.40.10 155 303 2.3E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_1234 d11420e983579ad08be3d5a7c4a41ef8 420 SUPERFAMILY SSF48452 168 269 3.56E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MCR_0898 42ee011d916fea6c3aaba3f3e8de54e3 380 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 119 135 - T 14-10-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0898 42ee011d916fea6c3aaba3f3e8de54e3 380 Pfam PF00268 Ribonucleotide reductase, small chain 36 336 7.5E-52 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MCR_0898 42ee011d916fea6c3aaba3f3e8de54e3 380 SUPERFAMILY SSF47240 7 344 1.03E-109 T 14-10-2018 IPR009078 Ferritin-like superfamily MCR_0898 42ee011d916fea6c3aaba3f3e8de54e3 380 Gene3D G3DSA:1.10.620.20 6 344 8.0E-141 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 MCR_1336 b699b1a98d54174e38fae5b6d2c17a77 542 Pfam PF01384 Phosphate transporter family 71 531 5.3E-113 T 14-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 MCR_0742 60f8a34384cf5f07ae928a7a6b206ebe 299 Pfam PF05940 NnrS protein 2 293 3.8E-60 T 14-10-2018 IPR010266 NnrS MCR_0628 a1a64976807d2a303f0f35d6fcca98ad 239 PIRSF PIRSF009160 1 239 1.7E-61 T 14-10-2018 IPR010539 Protein of unknown function UCP009160 MCR_0628 a1a64976807d2a303f0f35d6fcca98ad 239 Pfam PF12811 Bax inhibitor 1 like 3 238 5.0E-59 T 14-10-2018 IPR010539 Protein of unknown function UCP009160 MCR_0797 4a8dc35f52c6cdf5adccead4ea87cc65 322 SUPERFAMILY SSF74653 99 313 1.44E-7 T 14-10-2018 MCR_0797 4a8dc35f52c6cdf5adccead4ea87cc65 322 Gene3D G3DSA:3.30.1150.10 170 315 9.1E-6 T 14-10-2018 MCR_0451 3785d6a7910141820007cf461c8fdc76 200 Gene3D G3DSA:1.10.357.10 2 160 9.1E-9 T 14-10-2018 MCR_0451 3785d6a7910141820007cf461c8fdc76 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 4 24 5.1E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MCR_0876 d2161843e1b635dac385b92a7dc2be46 422 Pfam PF11067 Protein of unknown function (DUF2868) 167 401 8.8E-26 T 14-10-2018 IPR021296 Protein of unknown function DUF2868 MCR_0972 487e0c4e6e52d9f8387af8b26b1d5b2e 366 Pfam PF12698 ABC-2 family transporter protein 20 356 9.9E-27 T 14-10-2018 MCR_1224 ebea555ff7a1cd5ddfca8e376f7cdfb8 55 Gene3D G3DSA:2.10.70.10 15 55 5.5E-17 T 14-10-2018 MCR_1224 ebea555ff7a1cd5ddfca8e376f7cdfb8 55 Pfam PF10636 Hemin uptake protein hemP 20 55 3.6E-17 T 14-10-2018 IPR019600 Hemin uptake protein HemP MCR_0642 d4ada590075e116e66cd362329a024c3 297 Pfam PF04228 Putative neutral zinc metallopeptidase 1 292 2.6E-107 T 14-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative MCR_0691 845947014d8b8944192c889a4eca2cfc 105 Pfam PF13670 Peptidase propeptide and YPEB domain 15 101 7.1E-14 T 14-10-2018 IPR025711 PepSY domain MCR_1299 dd8f8a9bcea657ca3b3b5ad1850bb636 344 SUPERFAMILY SSF56935 28 325 1.77E-33 T 14-10-2018 MCR_1299 dd8f8a9bcea657ca3b3b5ad1850bb636 344 Gene3D G3DSA:2.40.160.10 28 337 1.2E-35 T 14-10-2018 IPR023614 Porin domain superfamily MCR_1299 dd8f8a9bcea657ca3b3b5ad1850bb636 344 Pfam PF13609 Gram-negative porin 23 323 8.2E-24 T 14-10-2018 MCR_1820 a8c4058826bd4246778d120ca5718166 359 Pfam PF01699 Sodium/calcium exchanger protein 33 186 1.9E-11 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MCR_1820 a8c4058826bd4246778d120ca5718166 359 Pfam PF01699 Sodium/calcium exchanger protein 215 356 1.4E-7 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MCR_0079 b1a640e931c79df2f51833cff4fd9cf5 410 SUPERFAMILY SSF56935 31 410 8.35E-18 T 14-10-2018 MCR_0079 b1a640e931c79df2f51833cff4fd9cf5 410 Pfam PF13557 Putative MetA-pathway of phenol degradation 113 325 8.2E-5 T 14-10-2018 IPR025737 MetA-pathway of phenol degradation, putative MCR_1348 a0316d8596b267d2c63bc51d30bea3e4 318 Pfam PF03547 Membrane transport protein 162 305 4.1E-11 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 MCR_1197 a7b5e1c873cc8dbbbbac9062b9a69977 153 Pfam PF12821 Threonine/Serine exporter, ThrE 10 143 5.4E-25 T 14-10-2018 IPR024528 Threonine/Serine exporter, ThrE MCR_0434 9a156d9d13b9a78e0185846c102cb754 218 Gene3D G3DSA:2.60.40.1190 31 218 2.1E-6 T 14-10-2018 MCR_0509 f158d456705b52666f3db4876fe9670e 150 Pfam PF05425 Copper resistance protein D 45 142 8.5E-9 T 14-10-2018 IPR008457 Copper resistance protein D GO:0016021 MCR_0316 75260ab7dab431e744f8bd924b884481 349 Pfam PF06189 5'-nucleotidase 46 317 4.5E-103 T 14-10-2018 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821|Reactome: R-HSA-74259 MCR_0527 381271f4418c06b12bffbc845f0a450f 284 Gene3D G3DSA:3.60.110.10 2 282 2.7E-73 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MCR_0527 381271f4418c06b12bffbc845f0a450f 284 SUPERFAMILY SSF56317 2 278 2.75E-59 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MCR_0527 381271f4418c06b12bffbc845f0a450f 284 Pfam PF00795 Carbon-nitrogen hydrolase 4 265 1.0E-39 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MCR_0565 9c873bed3cb03c8cbbf5a7a0916c3852 431 SUPERFAMILY SSF81301 5 136 1.06E-18 T 14-10-2018 MCR_1609 2a5ccc03882ce1ee284d1f00966f1e23 187 Pfam PF02325 YGGT family 10 78 1.5E-6 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020 MCR_1609 2a5ccc03882ce1ee284d1f00966f1e23 187 Pfam PF02325 YGGT family 107 176 2.5E-10 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020 MCR_0924 a71b7a9632a823a39f3f42a92ea5e277 170 Pfam PF02674 Colicin V production protein 4 141 6.1E-24 T 14-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 MCR_1321 e3162ef2ba1046b6e1b95cc6022eac5e 60 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 6 44 6.7E-11 T 14-10-2018 IPR008621 Cbb3-type cytochrome oxidase component MCR_1538 2aa5fb066c2fbd1c1779f9cbd1c7b81f 391 Pfam PF01098 Cell cycle protein 20 379 3.8E-82 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MCR_0551 d0cf46ac0361997b1f43eca83328fb0d 42 Pfam PF16951 Putative methionine and alanine importer, small subunit 1 32 9.5E-10 T 14-10-2018 IPR031596 Putative methionine and alanine importer, small subunit MCR_0576 353a9e2f1293a3cb03614b8fe7735dab 369 Pfam PF01594 AI-2E family transporter 14 344 2.9E-54 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like MCR_1633 ba5d4cfc2f683725b2832bea0bf0ebb8 84 Pfam PF14090 Helix-turn-helix domain 2 65 7.0E-12 T 14-10-2018 MCR_1777 e6298e0176124225abe2f9b136bd47de 116 Pfam PF04999 Cell division protein FtsL 13 102 1.6E-19 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 MCR_1227 13fcd1fdfd61b1008e12781cee61902b 1672 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1324 1672 1.3E-39 T 14-10-2018 IPR007452 Translocation and assembly module TamB MCR_1310 f1bd77f13df44c935a7762d2409d5385 99 Pfam PF14131 Domain of unknown function (DUF4298) 1 93 2.2E-28 T 14-10-2018 IPR025384 Protein of unknown function DUF4298 MCR_1752 97d3f25195d36d2a1ef57e296b68e12e 164 Pfam PF06271 RDD family 20 156 2.9E-26 T 14-10-2018 IPR010432 RDD MCR_0798 1cd9f2e9d7f996468122e32d87b317ef 182 Pfam PF01618 MotA/TolQ/ExbB proton channel family 60 166 1.5E-33 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MCR_0823 248cf8dedce70c9290b3a83d759d5826 615 Pfam PF02652 L-lactate permease 35 583 5.8E-105 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 MCR_1830 44a41e7625cd17ed7d6ccc3abc4bfa26 200 SUPERFAMILY SSF116846 40 79 1.96E-5 T 14-10-2018 IPR036181 MIT domain superfamily MCR_0680 62c9824ddbc95d2a05d0c0868327fd5f 230 Pfam PF04172 LrgB-like family 14 225 2.9E-45 T 14-10-2018 IPR007300 CidB/LrgB family MCR_0857 d52550dd803aa0a1c97262cacfd02ea5 76 Pfam PF04102 SlyX 12 76 5.1E-16 T 14-10-2018 IPR007236 SlyX MCR_1891 4cdc987f3dd7c37350b2b36ddbad7243 86 Pfam PF04226 Transglycosylase associated protein 34 79 3.6E-11 T 14-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 MCR_0101 26196dcb33aa1c9cb28de93510a45cf6 95 Gene3D G3DSA:2.40.420.20 73 95 1.9E-7 T 14-10-2018 MCR_0101 26196dcb33aa1c9cb28de93510a45cf6 95 Gene3D G3DSA:2.40.30.170 2 72 1.9E-7 T 14-10-2018