locus-tag	class	description
HH214_00025	ENOG4105CTJ	Metal Dependent Phosphohydrolase
HH214_00035	ENOG4105DUX	Transporter
HH214_00040	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HH214_00045	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HH214_00050	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HH214_00070	ENOG4105D2N	Aldolase
HH214_00075	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HH214_00085	ENOG4107QI6	Cysteine desulfurase
HH214_00090	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HH214_00110	ENOG4105DT9	hydrolase family 43
HH214_00120	ENOG4105C1J	atp-dependent rna helicase
HH214_00150	ENOG4105T58	Dithiol-disulfide isomerase
HH214_00155	ENOG4105CHM	Aminotransferase
HH214_00160	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HH214_00195	ENOG4105CV8	reductase
HH214_00225	ENOG4105CG5	Glycosyl transferase (Group 1
HH214_00250	ENOG4105E2K	Glycosyl transferase (Group 1
HH214_00275	ENOG4105D3Q	Sugar transferase
HH214_00280	ENOG4105C30	Nad-dependent epimerase dehydratase
HH214_00285	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HH214_00295	ENOG4107T8Q	Glycosyl transferase (Group 1
HH214_00310	ENOG4108UUM	single-stranded DNA-binding protein
HH214_00320	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HH214_00325	ENOG4105CG3	alpha amylase, catalytic region
HH214_00330	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HH214_00340	ENOG4108J2P	Alpha beta hydrolase fold
HH214_00345	ENOG4105EXC	Acyl-transferase
HH214_00370	ENOG4105C3G	gtp-binding protein
HH214_00375	ENOG4105CJW	magnesium transporter
HH214_00385	ENOG4105BZ1	(ABC) transporter
HH214_00390	ENOG4107R6T	Involved in the transcription termination process (By similarity)
HH214_00400	ENOG4105VIE	preprotein translocase, subunit YajC
HH214_00410	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HH214_00435	ENOG4108RWN	rrna methyltransferase
HH214_00450	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HH214_00470	ENOG4105C5H	ABC transporter
HH214_00480	ENOG4108S4H	thioesterase Superfamily protein
HH214_00485	ENOG4108UVJ	appr-1-p processing domain protein
HH214_00490	ENOG4105CPC	Aldo Keto reductase
HH214_00500	ENOG4105BZU	Histidine kinase
HH214_00520	ENOG4105BZU	Histidine kinase
HH214_00525	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HH214_00530	ENOG4105C02	permease
HH214_00550	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HH214_00580	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HH214_00590	ENOG4105C31	Tryptophanyl-tRNA synthetase
HH214_00595	ENOG4105ZMH	deoxynucleoside kinase
HH214_00600	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HH214_00605	ENOG4108K5P	(LipO)protein
HH214_00625	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HH214_00640	ENOG4105DVT	helicase
HH214_00675	ENOG4107RBB	ABC transporter, permease
HH214_00685	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HH214_00695	ENOG4105CNU	cell division protein FtsK
HH214_00740	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HH214_00755	ENOG4105CH7	arginosuccinase
HH214_00760	ENOG4108UUM	single-stranded DNA-binding protein
HH214_00780	ENOG41081XQ	Conserved Protein
HH214_00785	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HH214_00815	ENOG4105CSH	Transporter
HH214_00825	ENOG4107S5I	aldo keto reductase
HH214_00835	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HH214_00850	ENOG4105DR9	pseudouridine synthase
HH214_00885	ENOG4105WAB	arsR family transcriptional regulator
HH214_00890	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HH214_00910	ENOG4105VFU	Rna-binding protein
HH214_00935	ENOG4105BZU	Histidine kinase
HH214_00940	ENOG4105BZU	Histidine kinase
HH214_00945	ENOG4105WH1	Two component transcriptional regulator luxr family
HH214_00995	ENOG4105BZU	Histidine kinase
HH214_01000	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
HH214_01010	ENOG4107R7I	amino acid
HH214_01015	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
HH214_01025	ENOG4105EF1	ribulokinase
HH214_01120	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HH214_01145	ENOG4105D3Q	Sugar transferase
HH214_01155	ENOG4105K64	Glycosyl transferase, family 2
HH214_01160	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HH214_01175	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HH214_01205	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HH214_01220	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HH214_01235	ENOG4105CTX	dehydratase
HH214_01240	ENOG4107QZW	Altronate oxidoreductase
HH214_01255	ENOG4105F5H	Glycosyl Hydrolase Family 88
HH214_01275	ENOG4107TDE	lipolytic protein G-D-S-L family
HH214_01290	ENOG4105ETE	Transcriptional regulator (LacI family
HH214_01300	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HH214_01310	ENOG4107TTQ	Alpha beta hydrolase fold
HH214_01320	ENOG4105VDW	Csbd family
HH214_01325	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HH214_01330	ENOG4105KDC	50s ribosomal protein l28
HH214_01335	ENOG41083ND	50S ribosomal protein L33
HH214_01345	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HH214_01350	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HH214_01355	ENOG41074B2	UPF0747 protein
HH214_01425	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
HH214_01430	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HH214_01440	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HH214_01445	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HH214_01465	ENOG4105EDR	glucose galactose transporter
HH214_01490	ENOG4105F5W	AtP-binding protein
HH214_01495	ENOG4105D70	Integrase catalytic subunit
HH214_01525	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HH214_01540	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HH214_01545	ENOG4107VMU	Membrane
HH214_01585	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HH214_01590	ENOG4105C2X	Arabinose 5-phosphate isomerase
HH214_01605	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HH214_01610	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HH214_01630	ENOG4108JQ6	ABC transporter
HH214_01635	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HH214_01645	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HH214_01650	ENOG4105BZU	Histidine kinase
HH214_01655	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HH214_01660	ENOG4105C8S	subunit m
HH214_01670	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HH214_01685	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HH214_01690	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HH214_01705	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HH214_01710	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HH214_01725	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HH214_01745	ENOG4105EMU	Dehydrogenase
HH214_01755	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HH214_01770	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HH214_01780	ENOG4105C2I	pirin domain protein
HH214_01795	ENOG4107XWI	flavin reductase domain protein, FMN-binding
HH214_01800	ENOG4108W6C	Dehydrogenase
HH214_01815	ENOG4105CUB	amino acid
HH214_01820	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HH214_01845	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HH214_01850	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HH214_01860	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HH214_01870	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HH214_01880	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HH214_01885	ENOG4105JVQ	RNA Polymerase
HH214_01900	ENOG4105C8Y	Acetylornithine aminotransferase
HH214_01910	ENOG4105CPK	Glycosyl transferase (Group 1
HH214_01915	ENOG4105CKB	glycosidase
HH214_01935	ENOG4105C0B	DNA polymerase III (alpha subunit)
HH214_01940	ENOG4105E0X	reductase
HH214_01950	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HH214_01960	ENOG4107QJT	sodium dicarboxylate symporter
HH214_01970	ENOG4105C8T	Leucyl-tRNA synthetase
HH214_01980	ENOG4105CH6	catalase
HH214_01985	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HH214_01995	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HH214_02000	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HH214_02005	ENOG4105PGM	cation diffusion facilitator family transporter
HH214_02015	ENOG4108ZCU	PPIases accelerate the folding of proteins
HH214_02025	ENOG4105C3M	thioredoxin reductase
HH214_02045	ENOG4108URH	decarboxylase
HH214_02050	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HH214_02060	ENOG4105CHR	reductase
HH214_02065	ENOG4105C9K	Endothelin-converting enzyme 1
HH214_02075	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HH214_02085	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HH214_02115	ENOG4105BZU	Histidine kinase
HH214_02140	ENOG4105WH1	Two component transcriptional regulator luxr family
HH214_02150	ENOG4105C3F	Signal peptidase i
HH214_02155	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HH214_02165	ENOG4105FA0	parb-like partition protein
HH214_02170	ENOG4107QJE	Chromosome Partitioning Protein
HH214_02175	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HH214_02225	ENOG4105DTN	riboflavin biosynthesis protein ribF
HH214_02240	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HH214_02250	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HH214_02260	ENOG4105DXN	mazG family
HH214_02270	ENOG4105EMN	RNA polymerase sigma factor
HH214_02290	ENOG4105EHZ	conserved protein UCP016719
HH214_02295	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HH214_02310	ENOG4105C34	Pseudouridine synthase
HH214_02320	ENOG4105K6H	D-cysteine desulfhydrase
HH214_02340	ENOG4108V06	Glutathione peroxidase
HH214_02350	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HH214_02355	ENOG41090R7	Ferric uptake
HH214_02360	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HH214_02365	ENOG4105CRQ	synthase (Component I)
HH214_02370	ENOG4105CAT	Cytidine monophosphate kinase
HH214_02375	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HH214_02380	ENOG4105C3F	Signal peptidase i
HH214_02390	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HH214_02405	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HH214_02410	ENOG4107SRH	Nad-dependent epimerase dehydratase
HH214_02415	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HH214_02420	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HH214_02435	ENOG4107YWA	deoxycytidylate deaminase
HH214_02450	ENOG4105K46	50S ribosomal protein l27
HH214_02455	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HH214_02480	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HH214_02520	ENOG4108ZG0	Ompa motb domain protein
HH214_02550	ENOG4108428	Inherit from COG: -acetyltransferase
HH214_02555	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HH214_02580	ENOG4105HY2	Glycosidase related protein
HH214_02595	ENOG4105C7W	Xanthine dehydrogenase
HH214_02605	ENOG41075H3	AraC family transcriptional regulator
HH214_02635	ENOG4105DUM	transcriptional regulator, lysR family
HH214_02640	ENOG4105HMI	Membrane
HH214_02695	ENOG4105Q95	Cupin 2, conserved barrel domain protein
HH214_02705	ENOG4105DND	Transcriptional regulator
HH214_02710	ENOG4105C0D	helicase
HH214_02715	ENOG4105EMU	Dehydrogenase
HH214_02725	ENOG4105D9P	serine threonine protein kinase
HH214_02735	ENOG4107QHZ	cell cycle protein
HH214_02740	ENOG4108ZF3	Phosphatase
HH214_02750	ENOG4105D9P	serine threonine protein kinase
HH214_02755	ENOG41077A9	carbonic anhydrase
HH214_02760	ENOG4105EMU	Dehydrogenase
HH214_02785	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
HH214_02795	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HH214_02800	ENOG4105Y7M	Transcriptional regulator, TetR family
HH214_02805	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HH214_02810	ENOG4108IUM	Glycogen debranching enzyme
HH214_02830	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HH214_02840	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HH214_02875	ENOG4105DWT	malate dehydrogenase (quinone)
HH214_02880	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HH214_02935	ENOG4105C26	Dehydrogenase
HH214_02945	ENOG4108UHU	Aldolase
HH214_02955	ENOG4105D2H	Uronic isomerase
HH214_02965	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HH214_02970	ENOG4105C0D	helicase
HH214_02985	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HH214_03005	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HH214_03015	ENOG4107Y2X	deaminase
HH214_03025	ENOG4105VEJ	Heat shock protein
HH214_03035	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HH214_03045	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HH214_03050	ENOG4105CNI	cell division protein FtsW
HH214_03055	ENOG4105CJN	penicillin-binding protein
HH214_03070	ENOG4105DFF	Rod shape-determining protein mreb
HH214_03075	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HH214_03080	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HH214_03085	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HH214_03095	ENOG4107RBB	ABC transporter, permease
HH214_03110	ENOG4108IG5	Transcriptional regulator
HH214_03125	ENOG4105DR9	pseudouridine synthase
HH214_03130	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HH214_03135	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HH214_03150	ENOG4105CJ1	ABC, transporter
HH214_03165	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HH214_03170	ENOG4105C1J	atp-dependent rna helicase
HH214_03205	ENOG4105C7S	Dehydrogenase
HH214_03210	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HH214_03215	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HH214_03220	ENOG4108Z12	YiaAB two helix domain-containing protein
HH214_03230	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HH214_03250	ENOG4105DEF	Extracellular solute-binding protein, family 5
HH214_03255	ENOG4108I0Z	Aconitate hydratase
HH214_03260	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HH214_03270	ENOG4107RJ9	Cell division protein FtsX
HH214_03280	ENOG4105ID8	Transcriptional regulator, ARAC family
HH214_03285	ENOG4105EMU	Dehydrogenase
HH214_03290	ENOG4108FN7	Aldo keto reductase
HH214_03300	ENOG4105BZ1	(ABC) transporter
HH214_03305	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HH214_03325	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HH214_03330	ENOG4105DU6	RNA polymerase
HH214_03340	ENOG4105CSM	endonuclease III
HH214_03355	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HH214_03360	ENOG4105E1F	short-chain dehydrogenase reductase
HH214_03365	ENOG4105CPC	Aldo Keto reductase
HH214_03395	ENOG4108Z9K	Osmotically inducible protein
HH214_03430	ENOG4105ID8	Transcriptional regulator, ARAC family
HH214_03495	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HH214_03515	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HH214_03520	ENOG4105CMR	udp-glucose 4-epimerase
HH214_03525	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HH214_03530	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HH214_03555	ENOG4105D8V	Glucose sorbosone dehydrogenase
HH214_03560	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HH214_03570	ENOG41090A1	ferritin
HH214_03580	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HH214_03585	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HH214_03590	ENOG4105BZU	Histidine kinase
HH214_03605	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HH214_03630	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HH214_03650	ENOG4105C9K	Endothelin-converting enzyme 1
HH214_03690	ENOG4105N5T	Radical SAM Protein
HH214_03695	ENOG4105CPC	Aldo Keto reductase
HH214_03775	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HH214_03825	ENOG4105C27	TonB-dependent Receptor Plug
HH214_03830	ENOG4108IUK	alpha amylase, catalytic
HH214_03880	ENOG4105CD3	dihydroorotase
HH214_03890	ENOG4105BZU	Histidine kinase
HH214_03895	ENOG4108FN7	Aldo keto reductase
HH214_03900	ENOG4105C26	Dehydrogenase
HH214_03910	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
HH214_03915	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HH214_03925	ENOG4105DA4	cytochrome c-type biogenesis protein
HH214_03940	ENOG4105E2D	ec 3.2.1.52
HH214_03950	ENOG41077A9	carbonic anhydrase
HH214_03980	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HH214_03985	ENOG4105KR8	Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HH214_04000	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HH214_04045	ENOG4105CJ1	ABC, transporter
HH214_04065	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HH214_04080	ENOG4105DQR	SNARE associated Golgi
HH214_04125	ENOG4105C5H	ABC transporter
HH214_04160	ENOG4107ZXU	DSBA oxidoreductase
HH214_04165	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HH214_04170	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HH214_04195	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HH214_04210	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HH214_04215	ENOG4105CS2	ec 3.2.1.21
HH214_04225	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HH214_04235	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HH214_04265	ENOG4105KAV	tspo and mbr like protein
HH214_04395	ENOG4105EXC	Acyl-transferase
HH214_04440	ENOG4107SET	aldo keto reductase
HH214_04450	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HH214_04455	ENOG4105KVH	Transcriptional regulator
HH214_04460	ENOG4108RAV	Conserved protein
HH214_04470	ENOG4105DWY	Agmatine deiminase
HH214_04475	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HH214_04485	ENOG4108HRK	Histidine kinase
HH214_04490	ENOG4105DY9	regulatoR
HH214_04515	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HH214_04525	ENOG4105CSH	Transporter
HH214_04535	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
HH214_04550	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
HH214_04555	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HH214_04585	ENOG4105C6E	dna polymerase iii
HH214_04610	ENOG4105DG6	mannose-6-phosphate isomerase
HH214_04685	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HH214_04690	ENOG4105D3G	Pseudouridine synthase
HH214_04785	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HH214_04800	ENOG4107TDE	lipolytic protein G-D-S-L family
HH214_04815	ENOG4105CX8	fg-gap repeat protein
HH214_04860	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
HH214_04865	ENOG4107QR9	Iron-sulfur cluster binding protein
HH214_04870	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HH214_04880	ENOG4105C9F	isomerase
HH214_04890	ENOG4107YRA	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity)
HH214_04910	ENOG4105D4P	Coproporphyrinogen iii oxidase
HH214_04915	ENOG4105C5I	Dehydrogenase
HH214_04945	ENOG4108NEV	two component transcriptional regulator, LytTR family
HH214_04980	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HH214_05020	ENOG4107QVM	von Willebrand factor, type A
HH214_05025	ENOG4107QVM	von Willebrand factor, type A
HH214_05040	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HH214_05050	ENOG4107QJZ	Glycosyl transferase, family 2
HH214_05065	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HH214_05075	ENOG4105E6M	Sulphatase-modifying factor protein
HH214_05095	ENOG4105C37	(CBS) domain
HH214_05100	ENOG4105F0N	pyrophosphate phospho-hydrolase
HH214_05105	ENOG4105DQR	SNARE associated Golgi
HH214_05110	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HH214_05115	ENOG4105C8S	subunit m
HH214_05140	ENOG41067XB	TonB family
HH214_05165	ENOG4107TE5	Lipid kinase
HH214_05170	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HH214_05175	ENOG4105E53	ec 3.2.1.28
HH214_05180	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HH214_05190	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HH214_05195	ENOG4108IUZ	ABC transporter
HH214_05205	ENOG41082CH	UPF0145 protein
HH214_05225	ENOG4108EUD	Lysophospholipase
HH214_05230	ENOG4108UQS	dipeptidase
HH214_05240	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HH214_05250	ENOG4105DR5	peptidase
HH214_05255	ENOG4108Y6J	UPF0403 protein
HH214_05285	ENOG4105CHH	sulfate transporter
HH214_05310	ENOG4108SHN	Glycosyl transferase, family 2
HH214_05315	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HH214_05320	ENOG4105BZ1	(ABC) transporter
HH214_05330	ENOG4105F32	YngK protein
HH214_05335	ENOG4105CHR	reductase
HH214_05350	ENOG4107QRT	dEAD DEAH box helicase
HH214_05370	ENOG4107TT5	NLP P60 protein
HH214_05415	ENOG4107QXV	Phosphate transporter
HH214_05425	ENOG4105BZU	Histidine kinase
HH214_05440	ENOG41065KQ	synthase
HH214_05465	ENOG4105CPK	Glycosyl transferase (Group 1
HH214_05470	ENOG4107QK9	Beta-lactamase
HH214_05475	ENOG4105EFZ	amidohydrolase
HH214_05480	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HH214_05500	ENOG4105C8N	cysteinyl-tRNA synthetase
HH214_05510	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HH214_05515	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HH214_05525	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HH214_05535	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HH214_05565	ENOG4105R2R	Thioredoxin
HH214_05595	ENOG4105DVC	DnaJ domain protein
HH214_05615	ENOG4105DMW	Dehydrogenase reductase
HH214_05620	ENOG41067HS	methyltransferase
HH214_05625	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HH214_05630	ENOG4105E90	ABC transporter
HH214_05635	ENOG4108IJ8	ABC transporter
HH214_05640	ENOG4105C8B	TIGR00159 family
HH214_05730	ENOG4105F5W	AtP-binding protein
HH214_05735	ENOG4105D70	Integrase catalytic subunit
HH214_05770	ENOG4108M4U	conserved membrane protein
HH214_05775	ENOG4105EEQ	Na H antiporter
HH214_05795	ENOG4105D64	Mechanosensitive ion channel
HH214_05810	ENOG4105C0H	protease
HH214_05820	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HH214_05830	ENOG4105CCU	oxidase (Subunit III)
HH214_05845	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
HH214_05850	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HH214_05855	ENOG4105CHR	reductase
HH214_05880	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HH214_05900	ENOG4105D70	Integrase catalytic subunit
HH214_05905	ENOG4105F5W	AtP-binding protein
HH214_05915	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
HH214_05920	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HH214_05950	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HH214_05955	ENOG4105D05	Receptor
HH214_05985	ENOG4105E0X	reductase
HH214_05990	ENOG41090R7	Ferric uptake
HH214_05995	ENOG4105CKI	cobalamin synthesis protein
HH214_06015	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HH214_06025	ENOG4105CKI	cobalamin synthesis protein
HH214_06040	ENOG4105CH7	arginosuccinase
HH214_06045	ENOG4105CH7	arginosuccinase
HH214_06050	ENOG4105EMU	Dehydrogenase
HH214_06055	ENOG4105D70	Integrase catalytic subunit
HH214_06060	ENOG4105F5W	AtP-binding protein
HH214_06105	ENOG4105EYW	Ion transport protein
HH214_06110	ENOG4105CNU	cell division protein FtsK
HH214_06140	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HH214_06160	ENOG4105DQE	DNA ligase
HH214_06165	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HH214_06220	ENOG41076HS	cation diffusion facilitator family transporter
HH214_06230	ENOG4105D70	Integrase catalytic subunit
HH214_06235	ENOG4105F5W	AtP-binding protein
HH214_06240	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HH214_06255	ENOG4107R0I	Cell wall formation (By similarity)
HH214_06260	ENOG4105EMN	RNA polymerase sigma factor
HH214_06265	ENOG4105EWK	phytoene
HH214_06315	ENOG4108MYR	Secreted protein
HH214_06340	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HH214_06345	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HH214_06355	ENOG4105ECP	epimerase
HH214_06390	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
HH214_06410	ENOG4105CI3	gtp-binding protein typa
HH214_06440	ENOG4108NEV	two component transcriptional regulator, LytTR family
HH214_06445	ENOG4108HRK	Histidine kinase
HH214_06480	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HH214_06500	ENOG4105BZU	Histidine kinase
HH214_06515	ENOG4105C5W	Aldolase
HH214_06520	ENOG4108JYZ	YitT family
HH214_06525	ENOG4105ERH	Fumarylacetoacetate hydrolase
HH214_06530	ENOG4107SET	aldo keto reductase
HH214_06545	ENOG4105K63	Thioredoxin
HH214_06550	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HH214_06570	ENOG4107VIJ	nudix hydrolase
HH214_06605	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HH214_06610	ENOG4108HHA	Transketolase
HH214_06615	ENOG4108IUS	Transketolase
HH214_06625	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HH214_06665	ENOG4105KME	endoribonuclease L-psp
HH214_06675	ENOG4105CDV	Ompa motb domain protein
HH214_06680	ENOG4107RAQ	aminopeptidase
HH214_06685	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HH214_06690	ENOG4105CE4	GlcNAc 6-P deacetylase
HH214_06695	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HH214_06700	ENOG4105CE9	30S ribosomal protein S2
HH214_06705	ENOG4108UJD	30S ribosomal protein S9
HH214_06710	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HH214_06715	ENOG4105EGD	dinuclear metal center protein, YbgI family
HH214_06725	ENOG4105DEN	Luciferase family
HH214_06735	ENOG4105CHM	Aminotransferase
HH214_06740	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HH214_06755	ENOG4105D06	uba thif-type nad fad binding protein
HH214_06765	ENOG4108ZAF	Molybdopterin
HH214_06775	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HH214_06780	ENOG4105E0C	molybdate abc transporter
HH214_06785	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HH214_06795	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HH214_06810	ENOG4105C7W	Xanthine dehydrogenase
HH214_06815	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HH214_06820	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HH214_06825	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HH214_06830	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HH214_06835	ENOG4105C7W	Xanthine dehydrogenase
HH214_06865	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HH214_06890	ENOG4105DZ0	fad dependent oxidoreductase
HH214_06910	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HH214_06915	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HH214_06920	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HH214_06925	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HH214_06930	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HH214_06935	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HH214_06955	ENOG4108JQC	penicillin-binding protein 1A
HH214_06960	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HH214_06990	ENOG4105E6M	Sulphatase-modifying factor protein
HH214_07040	ENOG4105D7K	pfkb domain protein
HH214_07065	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HH214_07095	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HH214_07125	ENOG4108SJC	Membrane
HH214_07140	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HH214_07145	ENOG4105CCU	oxidase (Subunit III)
HH214_07150	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HH214_07155	ENOG4107SF2	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HH214_07160	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HH214_07190	ENOG4107SFQ	iron-sulfur binding
HH214_07210	ENOG4105BZU	Histidine kinase
HH214_07215	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HH214_07220	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HH214_07230	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HH214_07240	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HH214_07260	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HH214_07275	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HH214_07280	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HH214_07295	ENOG4108JJA	ABC, transporter
HH214_07300	ENOG4105FE9	pseudouridine synthase
HH214_07310	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HH214_07325	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HH214_07330	ENOG4105SCY	DNAK suppressor
HH214_07335	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HH214_07350	ENOG4105C2F	Histidine kinase
HH214_07355	ENOG4108NEV	two component transcriptional regulator, LytTR family
HH214_07360	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HH214_07365	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
HH214_07380	ENOG4107QRT	dEAD DEAH box helicase
HH214_07395	ENOG4107QKA	exodeoxyribonuclease V beta
HH214_07400	ENOG4105DSY	exodeoxyribonuclease V, gamma
HH214_07405	ENOG4107QYX	exodeoxyribonuclease v alpha
HH214_07545	ENOG41063TF	transcriptional regulator (AraC
HH214_07560	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HH214_07565	ENOG4105E7U	AraC family transcriptional regulator
HH214_07570	ENOG4105C0H	protease
HH214_07650	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HH214_07665	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HH214_07680	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HH214_07715	ENOG41080R2	UPF0102 protein
HH214_07720	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HH214_07730	ENOG4105C5S	asparaginyl-tRNA synthetase
HH214_07740	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HH214_07745	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HH214_07755	ENOG4108JGH	Tetr family transcriptional regulator
HH214_07770	ENOG4105CT7	inner membrane cred family protein
HH214_07780	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HH214_07790	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HH214_07805	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HH214_07810	ENOG4105C9K	Endothelin-converting enzyme 1
HH214_07815	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HH214_07830	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HH214_07835	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HH214_07840	ENOG4105DSJ	YicC domain protein
HH214_07850	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HH214_07860	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HH214_07890	ENOG41067XB	TonB family
HH214_07900	ENOG4105CY0	Metallo-Beta-Lactamase
HH214_07955	ENOG4107X35	defense response to bacterium
HH214_07970	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HH214_07985	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HH214_07990	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HH214_07995	ENOG4105FA2	dna polymerase iii
HH214_08000	ENOG4105MA4	psp1 domain protein
HH214_08020	ENOG4105CGY	Dna recombination protein
HH214_08030	ENOG4105C9Q	fumarate hydratase class II
HH214_08050	ENOG4105CUT	histidyl-tRNA synthetase
HH214_08065	ENOG4105CGK	Exodeoxyribonuclease III
HH214_08090	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HH214_08105	ENOG4105EEI	dihydropteroate synthase
HH214_08110	ENOG4107T0X	DNA ligase
HH214_08115	ENOG4107T0X	DNA ligase
HH214_08120	ENOG4105CN1	protease
HH214_08155	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HH214_08160	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HH214_08180	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HH214_08200	ENOG4105BZ1	(ABC) transporter
HH214_08205	ENOG4105C4R	Atp-dependent dna helicase
HH214_08225	ENOG4105BZU	Histidine kinase
HH214_08255	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HH214_08260	ENOG4105CI2	imidazolone-5-propionate hydrolase
HH214_08265	ENOG4105CD3	dihydroorotase
HH214_08280	ENOG4105DDQ	anthranilate synthase
HH214_08285	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HH214_08295	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HH214_08300	ENOG4105D1H	recombination factor protein RarA
HH214_08310	ENOG4105C9M	aspartyl-trna synthetase
HH214_08315	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HH214_08320	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HH214_08325	ENOG4105D9U	N-acetyltransferase
HH214_08350	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HH214_08355	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HH214_08370	ENOG4107XI7	Tetr family transcriptional regulator
HH214_08385	ENOG4105E1F	short-chain dehydrogenase reductase
HH214_08390	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HH214_08395	ENOG4105CGZ	zinc metallopeptidase
HH214_08415	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
HH214_08420	ENOG4105CHV	Transcription elongation factor NusA
HH214_08425	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HH214_08435	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
HH214_08445	ENOG4108VVK	transcriptional Regulator, AsnC
HH214_08450	ENOG4105BZM	domain protein
HH214_08470	ENOG4105CPP	Dehydrogenase, E1 component
HH214_08475	ENOG4105EXC	Acyl-transferase
HH214_08495	ENOG4105E2X	shikimate dehydrogenase
HH214_08510	ENOG4105C5X	domain protein
HH214_08515	ENOG4105D60	lipoprotein releasing system transmembrane protein
HH214_08525	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HH214_08545	ENOG4105CN1	protease
HH214_08575	ENOG4107SET	aldo keto reductase
HH214_08580	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HH214_08585	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HH214_08600	ENOG4105BZU	Histidine kinase
HH214_08845	ENOG4105C27	TonB-dependent Receptor Plug
HH214_08850	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HH214_08920	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
HH214_08925	ENOG4105C59	p-type ATPase
HH214_08945	ENOG4105E3B	Multicopper oxidase
HH214_08990	ENOG4105E3B	Multicopper oxidase
HH214_09005	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HH214_09010	ENOG4105GR3	Histidine kinase
HH214_09030	ENOG4105BZS	acriflavin resistance protein
HH214_09035	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HH214_09045	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
HH214_09050	ENOG4105KK4	UPF0060 membrane protein
HH214_09065	ENOG4105ECQ	AraC Family Transcriptional Regulator
HH214_09070	ENOG4105CHR	reductase
HH214_09075	ENOG4105ID8	Transcriptional regulator, ARAC family
HH214_09145	ENOG4107YH6	single-stranded DNA-binding protein
HH214_09160	ENOG4105EKQ	RNA-directed DNA polymerase
HH214_09165	ENOG4105BZU	Histidine kinase
HH214_09170	ENOG4105BZU	Histidine kinase
HH214_09230	ENOG4108W6C	Dehydrogenase
HH214_09260	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HH214_09265	ENOG4105F0N	pyrophosphate phospho-hydrolase
HH214_09270	ENOG4107R4J	Chloride channel
HH214_09280	ENOG4105WMR	Protein CrcB homolog
HH214_09305	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
HH214_09310	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HH214_09320	ENOG4105NQN	cytochrome C
HH214_09340	ENOG4105D3R	alkyl hydroperoxide reductase
HH214_09350	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HH214_09410	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
HH214_09435	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HH214_09445	ENOG4105HMI	Membrane
HH214_09455	ENOG4108M4U	conserved membrane protein
HH214_09470	ENOG4105E3B	Multicopper oxidase
HH214_09490	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HH214_09505	ENOG4105D70	Integrase catalytic subunit
HH214_09510	ENOG4105F5W	AtP-binding protein
HH214_09605	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HH214_09645	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HH214_09660	ENOG4105F5W	AtP-binding protein
HH214_09665	ENOG4105D70	Integrase catalytic subunit
HH214_09680	ENOG4105BZU	Histidine kinase
HH214_09685	ENOG4105C08	Histidine kinase
HH214_09695	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HH214_09705	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HH214_09740	ENOG4105DY9	regulatoR
HH214_09750	ENOG4108HRK	Histidine kinase
HH214_09760	ENOG4108UJV	acyl-CoA thioesterase i
HH214_09795	ENOG4105F5W	AtP-binding protein
HH214_09800	ENOG4105D70	Integrase catalytic subunit
HH214_09850	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HH214_09860	ENOG4105D6J	arsenicaL-resistance protein
HH214_09865	ENOG4108UXE	Protein tyrosine phosphatase
HH214_09885	ENOG4105BZU	Histidine kinase
HH214_09900	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HH214_09905	ENOG4108V06	Glutathione peroxidase
HH214_09915	ENOG4105DHJ	ABC, transporter
HH214_09935	ENOG4105C5H	ABC transporter
HH214_09945	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HH214_09955	ENOG4108Z0R	Transferase
HH214_09970	ENOG4108IYU	L-aspartate oxidase
HH214_09985	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HH214_09990	ENOG4107XQK	5-formyltetrahydrofolate cyclo-ligase
HH214_09995	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HH214_10000	ENOG4105DA5	(ABC) transporter
HH214_10005	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HH214_10010	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HH214_10015	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HH214_10020	ENOG4105DCI	Phosphohydrolase
HH214_10025	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HH214_10030	ENOG4105K8N	protein family UPF0079, ATPase
HH214_10035	ENOG4105DCF	alanine dehydrogenase
HH214_10040	ENOG4107S2Z	UPF0761 membrane protein
HH214_10055	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HH214_10095	ENOG4105DQ6	Transposase
HH214_10205	ENOG4106F1P	AAA ATPase, central domain protein
HH214_10215	ENOG4105KVH	Transcriptional regulator
HH214_10255	ENOG4108HRK	Histidine kinase
HH214_10260	ENOG4105DY9	regulatoR
HH214_10275	ENOG4105KVH	Transcriptional regulator
HH214_10310	ENOG4105J0Q	Transcriptional regulator
HH214_10315	ENOG4105C6T	cysteine synthase
HH214_10325	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HH214_10330	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HH214_10370	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HH214_10375	ENOG4105KVH	Transcriptional regulator
HH214_10390	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HH214_10400	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HH214_10475	ENOG4108VAC	response regulator
HH214_10480	ENOG4105DY9	regulatoR
HH214_10490	ENOG4108HRK	Histidine kinase
HH214_10500	ENOG4105DZP	Membrane-associated zinc metalloprotease
HH214_10510	ENOG4107YH6	single-stranded DNA-binding protein
HH214_10600	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HH214_10635	ENOG4105CN1	protease
HH214_10640	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HH214_10650	ENOG4105HFZ	Membrane
HH214_10660	ENOG4105C3R	Methionine synthase
HH214_10670	ENOG4105SYT	Methylenetetrahydrofolate reductase
HH214_10675	ENOG4105C2F	Histidine kinase
HH214_10680	ENOG4108VAC	response regulator
HH214_10705	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HH214_10715	ENOG4105CPF	Cell wall formation (By similarity)
HH214_10720	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HH214_10740	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HH214_10765	ENOG4105DGW	oligopeptidase A
HH214_10770	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HH214_10775	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HH214_10780	ENOG4105D29	Helix-turn-helix type 11 domain protein
HH214_10790	ENOG4108JQ1	Dehydrogenase
HH214_10795	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HH214_10820	ENOG4105DTD	Dehydrogenase
HH214_10825	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HH214_10855	ENOG4105CNT	hydrolase family 2
HH214_10865	ENOG4108JYZ	YitT family
HH214_10905	ENOG4105CPC	Aldo Keto reductase
HH214_10915	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HH214_10925	ENOG4105BZU	Histidine kinase
HH214_10935	ENOG4105KNE	Phosphatidate cytidylyltransferase
HH214_10950	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HH214_10955	ENOG4105NWN	ApaG protein
HH214_10985	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
HH214_10990	ENOG4105CHR	reductase
HH214_11000	ENOG4105BZU	Histidine kinase
HH214_11030	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HH214_11035	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HH214_11040	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HH214_11050	ENOG41083MR	nifu domain-containing protein
HH214_11060	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HH214_11070	ENOG4107VXZ	Hydrolase
HH214_11075	ENOG4105C0H	protease
HH214_11080	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HH214_11105	ENOG4105E08	Glycoside hydrolase, family 9
HH214_11120	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HH214_11140	ENOG4105D9R	oxidoreductase
HH214_11155	ENOG4105EGD	dinuclear metal center protein, YbgI family
HH214_11175	ENOG4108JA2	transcriptioN-repair coupling factor
HH214_11200	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HH214_11205	ENOG4105C1V	Peptidase, M16
HH214_11210	ENOG4108ZAI	phosphatidylglycerophosphatase a
HH214_11215	ENOG41066YJ	Beta-lactamase
HH214_11220	ENOG4108YYS	metal-dependent hydrolase (By similarity)
HH214_11245	ENOG4105CJ1	ABC, transporter
HH214_11265	ENOG4105D98	threonine synthase
HH214_11270	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HH214_11280	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HH214_11285	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HH214_11290	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
HH214_11295	ENOG4107RBB	ABC transporter, permease
HH214_11300	ENOG4108N5B	2-phosphosulfolactate phosphatase
HH214_11305	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HH214_11315	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HH214_11325	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HH214_11345	ENOG4107R8N	Glycosyl transferase, family 2
HH214_11375	ENOG4105BZS	acriflavin resistance protein
HH214_11385	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HH214_11420	ENOG4105DTQ	mandelate racemase muconate lactonizing
HH214_11430	ENOG4105UEI	Transcriptional Regulator AraC Family
HH214_11445	ENOG4105K63	Thioredoxin
HH214_11485	ENOG4105BZU	Histidine kinase
HH214_11510	ENOG4105CDW	Resistance protein
HH214_11520	ENOG4107TS3	membrane protein, TerC
HH214_11535	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
HH214_11565	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HH214_11570	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HH214_11580	ENOG4105CE1	Ferrous iron transport protein b
HH214_11595	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HH214_11605	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HH214_11610	ENOG4107QR9	Iron-sulfur cluster binding protein
HH214_11615	ENOG4105IIU	Aminopeptidase
HH214_11630	ENOG4105TT1	Ragb susd domain-containing protein
HH214_11650	ENOG4105HY2	Glycosidase related protein
HH214_11655	ENOG4105DFY	n-acylglucosamine 2-epimerase
HH214_11660	ENOG4105EX0	alpha-galactosidase
HH214_11670	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
HH214_11680	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HH214_11685	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HH214_11690	ENOG4105C7W	Xanthine dehydrogenase
HH214_11695	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HH214_11725	ENOG4105I6B	RNA polymerase
HH214_11775	ENOG4105DR4	Methyltransferase
HH214_11785	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HH214_11790	ENOG4108Z7R	Chaperone CsaA
HH214_11795	ENOG4106AKJ	
HH214_11800	ENOG4108Z6B	deaminase
HH214_11805	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HH214_11815	ENOG4105CB2	alcohol dehydrogenase
HH214_11820	ENOG4108EX3	reductase
HH214_11825	ENOG4105C5Q	Transcriptional regulator
HH214_11830	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HH214_11840	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HH214_11845	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HH214_11850	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HH214_11860	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HH214_11875	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HH214_11880	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HH214_11915	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HH214_11920	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
HH214_11925	ENOG4105BZU	Histidine kinase
HH214_11935	ENOG4108V3W	Chemotaxis protein, CheW
HH214_11940	ENOG4105CBS	Chea signal transduction histidine kinase
HH214_12000	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HH214_12050	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
HH214_12075	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HH214_12090	ENOG4105D5D	udp-galactopyranose mutase
HH214_12095	ENOG4107R51	Glycosyl transferase, family 2
HH214_12105	ENOG4107R51	Glycosyl transferase, family 2
HH214_12120	ENOG4105HSS	phospholipase C
HH214_12125	ENOG4105CA0	peroxidase
HH214_12130	ENOG4108YZG	isomerase
HH214_12135	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HH214_12140	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HH214_12150	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HH214_12155	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HH214_12160	ENOG4105WXV	50S ribosomal protein L32
HH214_12180	ENOG4105FM1	phage shock protein C
HH214_12190	ENOG4105C27	TonB-dependent Receptor Plug
HH214_12225	ENOG4105VWP	Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding
HH214_12245	ENOG4107VXZ	Hydrolase
HH214_12255	ENOG4105C0H	protease
HH214_12280	ENOG4107GJV	short-chain dehydrogenase reductase
HH214_12305	ENOG4107R7I	amino acid
HH214_12310	ENOG4108Z9Z	response to DNA damage stimulus
HH214_12340	ENOG4105FQP	Beta-lactamase
HH214_12345	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HH214_12350	ENOG4107W2A	UPF0173 metal-dependent hydrolase
HH214_12360	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HH214_12365	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HH214_12375	ENOG4105C2M	dna polymerase I
HH214_12380	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HH214_12390	ENOG4105EZV	Transcriptional regulator
HH214_12400	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HH214_12405	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HH214_12420	ENOG4108REF	Sporulation integral membrane protein ytvi
HH214_12440	ENOG4105CX6	glutaminyL-tRNA synthetase
HH214_12475	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HH214_12480	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HH214_12485	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HH214_12490	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HH214_12565	ENOG4105KVH	Transcriptional regulator
HH214_12580	ENOG4105KVH	Transcriptional regulator
HH214_12595	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HH214_12600	ENOG4108IND	Tetr family transcriptional regulator
HH214_12605	ENOG4105ECQ	AraC Family Transcriptional Regulator
HH214_12615	ENOG4105EMU	Dehydrogenase
HH214_12640	ENOG4105C27	TonB-dependent Receptor Plug
HH214_12700	ENOG4105ID8	Transcriptional regulator, ARAC family
HH214_12705	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HH214_12710	ENOG4105CHR	reductase
HH214_12715	ENOG4108IND	Tetr family transcriptional regulator
HH214_12730	ENOG4105BZU	Histidine kinase
HH214_12775	ENOG4105BZU	Histidine kinase
HH214_12780	ENOG4105BZU	Histidine kinase
HH214_12785	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HH214_12815	ENOG4108V9W	transcriptional regulatory protein
HH214_12820	ENOG4105BZU	Histidine kinase
HH214_12845	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HH214_12855	ENOG4105C03	ribonuclease
HH214_12860	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HH214_12900	ENOG4105EE5	Membrane protein terC
HH214_12920	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
HH214_12930	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HH214_12935	ENOG4105C7K	acetolactate synthase
HH214_12975	ENOG4105MJ2	Competence protein
HH214_12980	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HH214_12985	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HH214_12990	ENOG410855V	Acylphosphatase
HH214_13000	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HH214_13020	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HH214_13025	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HH214_13030	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HH214_13035	ENOG4105E9H	Lytic Murein transglycosylase
HH214_13040	ENOG4105C6K	Malic enzyme
HH214_13045	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HH214_13055	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HH214_13065	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HH214_13075	ENOG4108JUA	Transcriptional regulator
HH214_13095	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HH214_13100	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HH214_13105	ENOG4105D64	Mechanosensitive ion channel
HH214_13130	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HH214_13170	ENOG4105EJQ	L-serine dehydratase
HH214_13175	ENOG410902K	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HH214_13185	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HH214_13195	ENOG4105PAD	Hydrolase
HH214_13200	ENOG4105ECJ	Glycosyl Transferase
HH214_13205	ENOG4105CPK	Glycosyl transferase (Group 1
HH214_13230	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
HH214_13240	ENOG4105DTQ	mandelate racemase muconate lactonizing
HH214_13265	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HH214_13295	ENOG41067QW	Transcriptional regulator
HH214_13300	ENOG4105C4R	Atp-dependent dna helicase
HH214_13305	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HH214_13310	ENOG4107QK2	May be the GTPase, regulating ATP sulfurylase activity (By similarity)
HH214_13315	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HH214_13325	ENOG410635A	Membrane
HH214_13335	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HH214_13345	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
HH214_13350	ENOG4105CMG	Carbohydrate kinase
HH214_13355	ENOG4105C93	Xylose Isomerase
HH214_13370	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
HH214_13375	ENOG4105ETE	Transcriptional regulator (LacI family
HH214_13380	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HH214_13385	ENOG4105HDK	L-asparaginase
HH214_13390	ENOG4105F8V	Hydrolase, tatD family
HH214_13395	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HH214_13400	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HH214_13405	ENOG4105SFS	phosphoesterase RecJ domain protein
HH214_13410	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HH214_13425	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HH214_13435	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HH214_13445	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HH214_13450	ENOG4105K6V	RNA polymerase
HH214_13465	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HH214_13470	ENOG4105BZU	Histidine kinase
HH214_13475	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HH214_13480	ENOG4105EUJ	GTP cyclohydrolase i
HH214_13495	ENOG4105E63	Pfam:DUF178
HH214_13500	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HH214_13505	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HH214_13510	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HH214_13515	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HH214_13520	ENOG4105C6K	Malic enzyme
HH214_13560	ENOG4108RWI	nicotinamidase
HH214_13580	ENOG4108RH7	phosphoglycerate mutase
HH214_13610	ENOG4105CMR	udp-glucose 4-epimerase
HH214_13615	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HH214_13620	ENOG4105CPQ	Dehydrogenase
HH214_13660	ENOG4105CWX	Alpha-1,2-mannosidase
HH214_13715	ENOG4105F0N	pyrophosphate phospho-hydrolase
HH214_13735	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HH214_13740	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HH214_13745	ENOG41081DX	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HH214_13750	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HH214_13755	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HH214_13760	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HH214_13765	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HH214_13770	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HH214_13775	ENOG4105WNB	50s ribosomal protein l29
HH214_13780	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HH214_13785	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HH214_13790	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HH214_13795	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HH214_13800	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HH214_13805	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HH214_13810	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HH214_13815	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HH214_13820	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HH214_13825	ENOG4105VPB	50S ribosomal protein L30
HH214_13830	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HH214_13835	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HH214_13845	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HH214_13850	ENOG410864M	50S ribosomal protein L36
HH214_13855	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HH214_13860	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HH214_13865	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HH214_13870	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HH214_13875	ENOG4108ZT0	50S ribosomal protein l17
HH214_13890	ENOG4105CFG	Acts as a chaperone (By similarity)
HH214_13920	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HH214_13925	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HH214_13930	ENOG4105D52	delta-aminolevulinic acid dehydratase
HH214_13940	ENOG4105BZU	Histidine kinase
HH214_13955	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HH214_13965	ENOG4105CI2	imidazolone-5-propionate hydrolase
HH214_13990	ENOG4105C7B	Threonine dehydratase
HH214_13995	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HH214_14000	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HH214_14010	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HH214_14020	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HH214_14025	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HH214_14030	ENOG4108ZP8	Acetolactate synthase small subunit
HH214_14035	ENOG4105C7K	acetolactate synthase
HH214_14040	ENOG4105C01	Dihydroxy-acid dehydratase
HH214_14045	ENOG4105T7Q	H transporting two-sector ATPase delta epsilon subunit
HH214_14050	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HH214_14085	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HH214_14095	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HH214_14100	ENOG4105ES4	Nitrilase
HH214_14110	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HH214_14120	ENOG4105BZA	Phosphoglycerate kinase
HH214_14140	ENOG4105DA5	(ABC) transporter
HH214_14155	ENOG41083X6	30S ribosomal protein S21
HH214_14160	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HH214_14210	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HH214_14215	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HH214_14220	ENOG4107VNI	ribosomal protein l10
HH214_14225	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HH214_14230	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HH214_14235	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HH214_14250	ENOG4105D75	Capsular exopolysaccharide family
HH214_14255	ENOG4107XZA	Glycosyl transferase family 2
HH214_14280	ENOG4108I69	Glycosyl transferases group 1
HH214_14305	ENOG4106WTF	Glycosyl transferase, family 2
HH214_14310	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HH214_14315	ENOG4106CD9	glycosyl transferase group 1
HH214_14320	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HH214_14325	ENOG4105C30	Nad-dependent epimerase dehydratase
HH214_14330	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HH214_14335	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HH214_14340	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HH214_14365	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HH214_14385	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HH214_14390	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HH214_14395	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
HH214_14410	ENOG4107MMM	Anti-sigma-factor antagonist
HH214_14415	ENOG4105FUA	antagonist
HH214_14420	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
HH214_14425	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
HH214_14430	ENOG4105BZU	Histidine kinase
HH214_14435	ENOG4105BZU	Histidine kinase
HH214_14475	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
HH214_14500	ENOG4105BZU	Histidine kinase
HH214_14505	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HH214_14510	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HH214_14535	ENOG4105DQ4	alcohol dehydrogenase
HH214_14545	ENOG4105BZS	acriflavin resistance protein
HH214_14555	ENOG4107Z3H	Transcriptional regulator, TetR family
HH214_14575	ENOG4105CHR	reductase
HH214_14580	ENOG4108WQI	RNA Polymerase
HH214_14625	ENOG4105WH1	Two component transcriptional regulator luxr family
HH214_14640	ENOG4105C5H	ABC transporter
HH214_14645	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HH214_14650	ENOG4108YZ4	nudix hydrolase
HH214_14655	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HH214_14675	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
HH214_14680	ENOG4105W5Q	DNA repair protein (RadC
HH214_14685	ENOG4105BZU	Histidine kinase
HH214_14700	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HH214_14705	ENOG4105CKK	Glycosyl transferase, family 2
HH214_14710	ENOG4105C7Z	Conserved Protein
HH214_14715	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HH214_14730	ENOG4108S4H	thioesterase Superfamily protein
HH214_14770	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
HH214_14780	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HH214_14805	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HH214_14815	ENOG4105BZU	Histidine kinase
HH214_14820	ENOG4105Q2H	domain protein
HH214_14850	ENOG4105GR3	Histidine kinase
HH214_14855	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HH214_14865	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HH214_14870	ENOG4105C72	UPF0176 protein
HH214_14890	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HH214_14895	ENOG4105C12	Phosphoribosylglycinamide synthetase
HH214_14925	ENOG4105CDY	transcriptional regulatory protein
HH214_14930	ENOG4105EXW	epimerase dehydratase
HH214_14935	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HH214_14945	ENOG4105DUM	transcriptional regulator, lysR family
HH214_14950	ENOG4108Z0Z	intracellular protease Pfpi family
HH214_14985	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HH214_14995	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HH214_15000	ENOG4105KHC	sulfurtransferase
HH214_15030	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HH214_15050	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HH214_15055	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HH214_15060	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HH214_15070	ENOG4105KUZ	arsenate reductase
HH214_15090	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
HH214_15120	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HH214_15125	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HH214_15130	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HH214_15135	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HH214_15140	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HH214_15165	ENOG4107R4J	Chloride channel
HH214_15180	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HH214_15190	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HH214_15210	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HH214_15215	ENOG4105CTQ	phosphohexokinase
HH214_15220	ENOG4105K5M	30s ribosomal protein S16
HH214_15225	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HH214_15230	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HH214_15235	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HH214_15240	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HH214_15265	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HH214_15275	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HH214_15285	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HH214_15295	ENOG4105C3M	thioredoxin reductase
HH214_15310	ENOG4105EIE	fructose-bisphosphate aldolase
HH214_15375	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HH214_15380	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HH214_15390	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HH214_15395	ENOG4107QHQ	amino acid
HH214_15400	ENOG4105CUB	amino acid
HH214_15410	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HH214_15415	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HH214_15425	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HH214_15440	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
HH214_15445	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
HH214_15460	ENOG4105D49	3-dehydroquinate synthase
HH214_15585	ENOG4105BZU	Histidine kinase
HH214_15620	ENOG4105BZU	Histidine kinase
HH214_15630	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HH214_15635	ENOG4105BZU	Histidine kinase
HH214_15640	ENOG4105BZU	Histidine kinase
HH214_15755	ENOG4105UTB	Blue (Type 1) copper domain protein
HH214_15765	ENOG4108V1U	phospholipid-binding protein
HH214_15780	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HH214_15795	ENOG4106R3P	AraC family transcriptional regulator
HH214_15805	ENOG4105CNT	hydrolase family 2
HH214_15810	ENOG4105BZU	Histidine kinase
HH214_15835	ENOG4105BZS	acriflavin resistance protein
HH214_15850	ENOG4107SF2	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HH214_15855	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
HH214_15890	ENOG4107YBY	Hydrolase
HH214_15905	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HH214_15925	ENOG4105BZU	Histidine kinase
HH214_15930	ENOG4105BZU	Histidine kinase
HH214_15950	ENOG4105ETE	Transcriptional regulator (LacI family
HH214_15960	ENOG4105CWX	Alpha-1,2-mannosidase
HH214_15965	ENOG4105CWX	Alpha-1,2-mannosidase
HH214_15970	ENOG4105C27	TonB-dependent Receptor Plug
HH214_15985	ENOG4105EDR	glucose galactose transporter
HH214_15995	ENOG4108Z9K	Osmotically inducible protein
HH214_16005	ENOG4105C0A	alcohol dehydrogenase
HH214_16010	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HH214_16015	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HH214_16035	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HH214_16050	ENOG4105CPQ	Dehydrogenase
HH214_16085	ENOG4105CNT	hydrolase family 2
HH214_16090	ENOG4107RJ1	sodium solute
HH214_16230	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HH214_16235	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
HH214_16240	ENOG4107QI6	Cysteine desulfurase
HH214_16265	ENOG4105ZRN	
HH214_16330	ENOG4105F9N	Major Facilitator Superfamily
HH214_16370	ENOG4105CHR	reductase
HH214_16385	ENOG4105EMU	Dehydrogenase
HH214_16390	ENOG4107Z6X	Transcriptional regulator
HH214_16395	ENOG4108RCM	Nitroreductase
HH214_16405	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HH214_16425	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
HH214_16430	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
HH214_16455	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HH214_16465	ENOG4105CHM	Aminotransferase
HH214_16475	ENOG4105CPP	Dehydrogenase, E1 component
HH214_16495	ENOG4105C02	permease
HH214_16500	ENOG4105DZP	Membrane-associated zinc metalloprotease
HH214_16505	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HH214_16520	ENOG4105K64	Glycosyl transferase, family 2
HH214_16545	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HH214_16565	ENOG4105EY8	ABC transporter
HH214_16585	ENOG4108KPZ	tonB-dependent Receptor
HH214_16600	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HH214_16605	ENOG4108YXG	UPF0502 protein
HH214_16610	ENOG4107YM1	mraZ protein
HH214_16615	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HH214_16625	ENOG4105CJN	penicillin-binding protein
HH214_16630	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HH214_16635	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HH214_16640	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HH214_16645	ENOG4105CNI	cell division protein FtsW
HH214_16650	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HH214_16655	ENOG4105DFU	Cell wall formation (By similarity)
HH214_16665	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HH214_16670	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HH214_16675	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HH214_16685	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HH214_16695	ENOG4107YZX	Universal stress protein
HH214_16700	ENOG4108JQ1	Dehydrogenase
HH214_16710	ENOG4105CYW	agmatinase
HH214_16720	ENOG4107ZT5	Thiol disulfide interchange protein
HH214_16770	ENOG4107RF4	Phosphodiesterase
HH214_16780	ENOG4105C02	permease
HH214_16785	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HH214_16820	ENOG4105CPC	Aldo Keto reductase
HH214_16825	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HH214_16840	ENOG4105M8K	biopolymer transport protein
HH214_16875	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HH214_16890	ENOG4105IIU	Aminopeptidase
HH214_16900	ENOG4105CHR	reductase
HH214_16910	ENOG4105DHJ	ABC, transporter
HH214_16915	ENOG4105CY3	ABC transporter, permease
HH214_16920	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HH214_16925	ENOG4105CH6	catalase
HH214_16940	ENOG4105EUB	pirin domain protein
HH214_16950	ENOG4105CHR	reductase
HH214_16955	ENOG4105FYV	Amp nucleosidase
HH214_16960	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HH214_16970	ENOG4107V87	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
HH214_16995	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HH214_17035	ENOG4107P26	
HH214_17040	ENOG4107QN2	dihydrolipoyl dehydrogenase
HH214_17050	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HH214_17080	ENOG4105DF5	DNA topoisomerase IV, subunit A
HH214_17100	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
HH214_17115	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HH214_17120	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HH214_17130	ENOG4105EMU	Dehydrogenase
HH214_17135	ENOG4105FM1	phage shock protein C
HH214_17170	ENOG4105DU6	RNA polymerase
HH214_17180	ENOG4105CK2	sodium dicarboxylate symporter
HH214_17190	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HH214_17210	ENOG4105CEV	competence damage-inducible protein
HH214_17215	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HH214_17220	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HH214_17225	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HH214_17255	ENOG4105EMN	RNA polymerase sigma factor
HH214_17260	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HH214_17285	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HH214_17290	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HH214_17295	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HH214_17325	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HH214_17330	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HH214_17335	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HH214_17340	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HH214_17345	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HH214_17350	ENOG4105CXT	aspartate transcarbamylase
HH214_17355	ENOG41066YJ	Beta-lactamase
HH214_17360	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HH214_17365	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HH214_17380	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HH214_17420	ENOG4105CUJ	penicillin amidase
HH214_17425	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HH214_17435	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HH214_17450	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HH214_17470	ENOG4107QQG	Dehydrogenase
HH214_17475	ENOG4107V1M	polysaccharide export protein
HH214_17485	ENOG4105CG5	Glycosyl transferase (Group 1
HH214_17490	ENOG4105E2K	Glycosyl transferase (Group 1
HH214_17500	ENOG4105CG5	Glycosyl transferase (Group 1
HH214_17505	ENOG4105GH9	galactofuranosyltransferase
HH214_17515	ENOG4105EY8	ABC transporter
HH214_17520	ENOG4105CG5	Glycosyl transferase (Group 1
HH214_17535	ENOG4107S6X	Glycosyl transferase, family 2
HH214_17585	ENOG4107S6X	Glycosyl transferase, family 2
HH214_17590	ENOG4105D5D	udp-galactopyranose mutase
HH214_17595	ENOG4105GH9	galactofuranosyltransferase
HH214_17615	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HH214_17620	ENOG4105D3Q	Sugar transferase
HH214_17630	ENOG4105ESV	Glycosyl transferase, family 4
HH214_17645	ENOG4105CG5	Glycosyl transferase (Group 1
HH214_17660	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HH214_17665	ENOG4108UW5	maltose o-acetyltransferase
HH214_17675	ENOG4107R51	Glycosyl transferase, family 2
HH214_17685	ENOG4105D3Q	Sugar transferase
HH214_17695	ENOG4105DEU	major facilitator superfamily
HH214_17700	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HH214_17705	ENOG4105C22	threonyL-tRNA synthetase
HH214_17710	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HH214_17715	ENOG4105VJV	50s ribosomal protein L35
HH214_17720	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HH214_17740	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
HH214_17760	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HH214_17775	ENOG4105VG0	50S ribosomal protein l34
HH214_17780	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HH214_17785	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HH214_17790	ENOG41072GX	Peptidase M22 Glycoprotease
HH214_17810	ENOG4105C25	Primosomal protein n'
HH214_17820	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HH214_17825	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HH214_17840	ENOG4105EW9	transcriptional regulator AsnC family
HH214_17845	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HH214_17860	ENOG4105EN6	Membrane
HH214_17865	ENOG4105CRK	lysyL-tRNA synthetase
HH214_17870	ENOG4108UW5	maltose o-acetyltransferase
HH214_17885	ENOG4108IQE	Amp-dependent synthetase and ligase
HH214_17895	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HH214_17900	ENOG4105C3J	Cysteine desulfurase
HH214_17905	ENOG4105CZQ	inner membrane transport protein YdhC
HH214_17910	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HH214_17920	ENOG4105CP7	Triose-phosphate isomerase
HH214_17925	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HH214_17930	ENOG4108RYK	Nad-dependent epimerase dehydratase
HH214_17935	ENOG4108Z40	Transcriptional regulator
HH214_17940	ENOG4108URH	decarboxylase
HH214_17950	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HH214_17960	ENOG4107GJV	short-chain dehydrogenase reductase
HH214_17965	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HH214_17975	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HH214_17980	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HH214_17985	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HH214_17990	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HH214_17995	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HH214_18000	ENOG4105BZU	Histidine kinase
HH214_18010	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HH214_18015	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HH214_18035	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HH214_18040	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HH214_18045	ENOG4105DIK	(ABC) transporter
HH214_18070	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HH214_18075	ENOG4105C8F	Beta-lactamase domain protein
HH214_18080	ENOG4107QN2	dihydrolipoyl dehydrogenase
HH214_18085	ENOG4108KPZ	tonB-dependent Receptor
HH214_18090	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HH214_18120	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HH214_18125	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HH214_18130	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HH214_18140	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HH214_18155	ENOG4107QUV	Domain protein
HH214_18165	ENOG4105BZU	Histidine kinase
HH214_18210	ENOG4105E2R	ROK family
HH214_18225	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HH214_18240	ENOG4105E2D	ec 3.2.1.52
HH214_18255	ENOG4105CWX	Alpha-1,2-mannosidase
HH214_18295	ENOG4105CNT	hydrolase family 2
HH214_18300	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HH214_18315	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HH214_18350	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HH214_18445	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HH214_18575	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
HH214_18580	ENOG4105DJ2	Major Facilitator Superfamily
HH214_18595	ENOG4105CUB	amino acid
HH214_18600	ENOG4105BZU	Histidine kinase
HH214_18605	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HH214_18630	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HH214_18670	ENOG4108EV3	Bifunctional aspartate kinase II homoserine dehydrogenase II
HH214_18685	ENOG4105DFA	alanine racemase domain protein
HH214_18695	ENOG4105C98	muts2 protein
HH214_18715	ENOG4105DBI	uridine monophosphokinase
HH214_18730	ENOG4108RMU	ferritin dps family protein
HH214_18745	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HH214_18750	ENOG4105C28	cystathionine
HH214_18765	ENOG4105D74	hydrolase
HH214_18820	ENOG4105KVH	Transcriptional regulator
HH214_18825	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HH214_18830	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HH214_18835	ENOG4105DN3	alpha-2-macroglobulin domain protein
HH214_18840	ENOG4108JQB	penicillin-binding protein 1C
HH214_18850	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HH214_18865	ENOG4108QD1	Membrane
HH214_18870	ENOG4105ZRN	
HH214_18875	ENOG4108K0D	peptidase, M48
HH214_18905	ENOG4107RMN	lycopene cyclase
HH214_18930	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HH214_18985	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HH214_19050	ENOG4108Z5V	transcriptional regulator, merr family
HH214_19055	ENOG4105CPF	Cell wall formation (By similarity)
HH214_19065	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HH214_19070	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HH214_19075	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HH214_19085	ENOG4105DJV	ribulose-phosphate 3-epimerase
HH214_19090	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HH214_19095	ENOG4108JQ1	Dehydrogenase
HH214_19105	ENOG4105CY0	Metallo-Beta-Lactamase
HH214_19110	ENOG4105BZ1	(ABC) transporter
HH214_19120	ENOG4105C9A	Phoh family
HH214_19125	ENOG4107QWK	SAICAR synthetase
HH214_19145	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HH214_19150	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HH214_19160	ENOG4105CEV	competence damage-inducible protein
HH214_19165	ENOG4105C7S	Dehydrogenase
HH214_19175	ENOG4105CKK	Glycosyl transferase, family 2
HH214_19190	ENOG4105DWV	Homoserine O-trans-acetylase
HH214_19195	ENOG4108IQK	o-acetylhomoserine
HH214_19205	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HH214_19215	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HH214_19225	ENOG4105EI2	Pseudouridine synthase
HH214_19235	ENOG410874W	AraC family transcriptional regulator
HH214_19245	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HH214_19255	ENOG4108KF3	Electron transport protein SCO1 SenC
HH214_19280	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HH214_19305	ENOG4107Y70	Heat shock protein
HH214_19310	ENOG4108VPT	UPF0234 protein
HH214_19325	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HH214_19335	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HH214_19340	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HH214_19350	ENOG4105ECY	inositol monophosphatase
HH214_19355	ENOG41083MR	nifu domain-containing protein
HH214_19400	ENOG4108UKZ	OsmC family
HH214_19405	ENOG4105C28	cystathionine
HH214_19410	ENOG4108ZG0	Ompa motb domain protein
HH214_19425	ENOG4106HK8	GPR1 FUN34 yaaH family protein
HH214_19430	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HH214_19440	ENOG4105CZK	Aspartate kinase
HH214_19450	ENOG4107T6X	nag kinase
HH214_19485	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HH214_19490	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
HH214_19500	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HH214_19515	ENOG4105EEQ	Na H antiporter
HH214_19520	ENOG4105BZP	glycoside hydrolase 15-related
HH214_19525	ENOG4105C02	permease
HH214_19535	ENOG4105ES5	Histidine kinase
HH214_19545	ENOG4107SUZ	Sodium/hydrogen exchanger family
HH214_19550	ENOG4105CZM	Major Facilitator
HH214_19555	ENOG4105C1Q	protoporphyrinogen oxidase
HH214_19560	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HH214_19565	ENOG4105CNN	ABC, transporter
HH214_19570	ENOG4105C2J	ABC transporter
HH214_19580	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HH214_19585	ENOG4108IUS	Transketolase
HH214_19590	ENOG4108HHA	Transketolase
HH214_19600	ENOG4105EMN	RNA polymerase sigma factor
HH214_19645	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HH214_19665	ENOG4105DFU	Cell wall formation (By similarity)
HH214_19700	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
HH214_19705	ENOG4105DKW	ABC transporter
HH214_19760	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HH214_19765	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HH214_19770	ENOG4108UJU	UPF0301 protein
HH214_19775	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HH214_19780	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HH214_19785	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HH214_19795	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HH214_19800	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HH214_19805	ENOG4105CBX	hi0933 family
HH214_19830	ENOG4105CPC	Aldo Keto reductase
HH214_19850	ENOG4108Z7F	N-acetyltransferase
HH214_19860	ENOG4108R6K	riboflavin synthase, subunit alpha
HH214_19875	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HH214_19885	ENOG4106N3A	copper homeostasis protein cutc
HH214_19900	ENOG4107RBB	ABC transporter, permease
HH214_19905	ENOG4105C1J	atp-dependent rna helicase
HH214_19935	ENOG4105BZU	Histidine kinase
HH214_19940	ENOG4107Z5C	methylesterase
HH214_19950	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HH214_19990	ENOG4105DA4	cytochrome c-type biogenesis protein
HH214_20010	ENOG4108ZIT	Ferredoxin, 2FE-2S
HH214_20020	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HH214_20025	ENOG4108Z03	MAF-like protein
HH214_20030	ENOG4105C9X	ppx gppa phosphatase
HH214_20040	ENOG4108IUX	(ABC) transporter
HH214_20045	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HH214_20050	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HH214_20055	ENOG4105CAK	Cell division ATP-binding protein ftsE
HH214_20070	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HH214_20075	ENOG4107SN7	NLP P60 protein
HH214_20085	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HH214_20090	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HH214_20095	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HH214_20100	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HH214_20105	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HH214_20110	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HH214_20115	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HH214_20120	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HH214_20125	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HH214_20160	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
HH214_20165	ENOG4107S5I	aldo keto reductase
HH214_20195	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HH214_20220	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HH214_20225	ENOG4105CDH	Citrulline--aspartate ligase
HH214_20250	ENOG4108ZGC	gaf domain protein
HH214_20260	ENOG4108VX5	3-methyladenine DNA glycosylase
HH214_20270	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
HH214_20275	ENOG4105DGU	Histone deacetylase
HH214_20280	ENOG4107QI1	Mate efflux family protein
HH214_20300	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HH214_20305	ENOG4105CKK	Glycosyl transferase, family 2
HH214_20310	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HH214_20345	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HH214_20370	ENOG4105ECP	epimerase
HH214_20380	ENOG4105VEQ	Cold shock protein
HH214_20395	ENOG4105CQB	FAD linked oxidase domain protein
HH214_20415	ENOG4107QYX	exodeoxyribonuclease v alpha
HH214_20425	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
HH214_20445	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HH214_20450	ENOG4105C5I	Dehydrogenase
HH214_20455	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HH214_20480	ENOG4107U9T	Pfam:Ribonuclease_BN
HH214_20505	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HH214_20515	ENOG4105DVY	radical SAM domain protein
HH214_20540	ENOG4105D3R	alkyl hydroperoxide reductase
HH214_20545	ENOG4105VEQ	Cold shock protein
HH214_20550	ENOG4107RGD	Major Facilitator superfamily
HH214_20555	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HH214_20565	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HH214_20590	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HH214_20595	ENOG4105EM2	membrane
HH214_20615	ENOG4105E6M	Sulphatase-modifying factor protein
HH214_20620	ENOG41061MV	Arylsulfatase
HH214_20670	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HH214_20675	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HH214_20680	ENOG4105CJW	magnesium transporter
HH214_20690	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HH214_20695	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HH214_20700	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HH214_20705	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HH214_20710	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HH214_20715	ENOG4105EGS	Mechanosensitive ion channel
HH214_20735	ENOG4105D7N	magnesium and cobalt transport protein CorA
HH214_20760	ENOG4105CPC	Aldo Keto reductase
HH214_20775	ENOG4107TJ9	Cytochrome
HH214_20785	ENOG4108JJB	ABC transporter
HH214_20790	ENOG4105C7J	ABC transporter, permease
HH214_20800	ENOG4105CHM	Aminotransferase
HH214_20805	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HH214_20810	ENOG4105CWX	Alpha-1,2-mannosidase
HH214_20815	ENOG4105CSR	polyphosphate kinase 2
HH214_20825	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HH214_20835	ENOG4105E0X	reductase
HH214_20855	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HH214_20860	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HH214_20875	ENOG4105C75	arginyL-tRNA synthetase
HH214_20905	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HH214_20920	ENOG4105EXC	Acyl-transferase
HH214_20935	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HH214_20940	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HH214_20955	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HH214_20965	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HH214_20980	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HH214_20985	ENOG4105CDU	Replicative dna helicase
HH214_21005	ENOG4105EAA	nucleoside
HH214_21010	ENOG4105E2A	Dehydrogenase
HH214_21015	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HH214_21030	ENOG4105C19	ABC transporter
HH214_21035	ENOG4107RBB	ABC transporter, permease
HH214_21040	ENOG4107RBB	ABC transporter, permease
HH214_21045	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HH214_21050	ENOG4107RBB	ABC transporter, permease
HH214_21070	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HH214_21085	ENOG4105BZU	Histidine kinase
HH214_21090	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HH214_21110	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HH214_21115	ENOG4105DIA	mandelate racemase muconate lactonizing
HH214_21120	ENOG4105CQB	FAD linked oxidase domain protein
HH214_21125	ENOG4108UJV	acyl-CoA thioesterase i
HH214_21135	ENOG4108I0Y	(ABC) transporter
HH214_21140	ENOG4107SUZ	Sodium/hydrogen exchanger family
HH214_21150	ENOG4105DEN	Luciferase family
HH214_21155	ENOG4105BZU	Histidine kinase
HH214_21160	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HH214_21180	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HH214_21190	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HH214_21215	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HH214_21225	ENOG4105BZU	Histidine kinase
HH214_21230	ENOG4105FFC	UPF0187 protein
HH214_21235	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HH214_21255	ENOG4105BZP	glycoside hydrolase 15-related
HH214_21260	ENOG4105BZU	Histidine kinase
HH214_21280	ENOG4105DY9	regulatoR
HH214_21315	ENOG4105C5I	Dehydrogenase
HH214_21505	ENOG4105F5W	AtP-binding protein
HH214_21510	ENOG4105D70	Integrase catalytic subunit
HH214_21555	ENOG4105DR5	peptidase
HH214_21665	ENOG4105WH1	Two component transcriptional regulator luxr family
HH214_21680	ENOG4107QJE	Chromosome Partitioning Protein
HH214_21730	ENOG4108Z7F	N-acetyltransferase
HH214_21735	ENOG4108UXE	Protein tyrosine phosphatase
HH214_21745	ENOG4105D6J	arsenicaL-resistance protein
HH214_21760	ENOG4105C59	p-type ATPase
HH214_21780	ENOG4105E3B	Multicopper oxidase