locus-tag class description AB431_00005 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) AB431_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AB431_00015 ENOG4108J5G 6-phosphogluconate dehydrogenase AB431_00020 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) AB431_00025 ENOG4105K7N UPF0232 protein AB431_00030 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB431_00035 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB431_00110 ENOG4105XBB septation inhibitor protein AB431_00125 ENOG4105D9P serine threonine protein kinase AB431_00130 ENOG4107TPY serine threonine protein kinase AB431_00150 ENOG4105HZM Fha domain containing protein AB431_00155 ENOG4105TV9 FHA Domain-Containing protein AB431_00175 ENOG4105BZU Histidine kinase AB431_00195 ENOG4105EFZ amidohydrolase AB431_00200 ENOG4105CUB amino acid AB431_00215 ENOG4105BZU Histidine kinase AB431_00230 ENOG4105EUB pirin domain protein AB431_00235 ENOG4105M5P UPF0310 protein AB431_00250 ENOG4105WH1 Two component transcriptional regulator luxr family AB431_00315 ENOG4108X6U May play a role in the intracellular transport of hydrophobic ligands AB431_00325 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AB431_00345 ENOG41080R8 Conserved Protein AB431_00355 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) AB431_00360 ENOG4105DFH Transport of potassium into the cell (By similarity) AB431_00395 ENOG4105CPQ Dehydrogenase AB431_00400 ENOG4105FBW Monooxygenase AB431_00425 ENOG410719E cytochrome p450 AB431_00435 ENOG4105PSQ Acyl-transferase AB431_00445 ENOG4108IPT Naphthoate synthase AB431_00450 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB431_00460 ENOG4105E39 Enoyl-CoA hydratase AB431_00480 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_00485 ENOG4105CHR reductase AB431_00580 ENOG4108M8W Monooxygenase AB431_00615 ENOG4105D2B acyl-CoA dehydrogenase AB431_00620 ENOG4105EMU Dehydrogenase AB431_00660 ENOG4105CEY Amp-dependent synthetase and ligase AB431_00670 ENOG4105CC9 acyl-Coa dehydrogenase AB431_00675 ENOG4105D2B acyl-CoA dehydrogenase AB431_00680 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr AB431_00735 ENOG4105C1G acyl-Coa dehydrogenase AB431_00740 ENOG4105CHU acetyl-coa acetyltransferase AB431_00750 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_00775 ENOG4105DYW oxidoreductase AB431_00835 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_00840 ENOG41076PI Short-chain dehydrogenase reductase Sdr AB431_00850 ENOG4108QIU Dehydrogenase AB431_00865 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_00885 ENOG4107QVM von Willebrand factor, type A AB431_00920 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AB431_00935 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein AB431_00940 ENOG41070F3 Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity) AB431_00950 ENOG4105DSY exodeoxyribonuclease V, gamma AB431_00955 ENOG4107QKA exodeoxyribonuclease V beta AB431_00960 ENOG4105C7H Helicase, RecD TraA family AB431_01015 ENOG4105IYB L-carnitine dehydratase bile acid-inducible protein F AB431_01030 ENOG4105C1G acyl-Coa dehydrogenase AB431_01040 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) AB431_01090 ENOG4107XGZ Hydrolase AB431_01110 ENOG4105EDW glycosyl transferase, family 39 AB431_01115 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) AB431_01135 ENOG4106N8J Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity) AB431_01140 ENOG4105CPQ Dehydrogenase AB431_01145 ENOG410905P Pyridoxamine 5-phosphate AB431_01180 ENOG4105F95 Monooxygenase AB431_01210 ENOG4107R50 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) AB431_01220 ENOG4105BZU Histidine kinase AB431_01270 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction AB431_01275 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) AB431_01285 ENOG4108VCT Sulfite exporter TauE/SafE AB431_01300 ENOG4105KRI phosphocarrier protein (HPr AB431_01305 ENOG4105DM4 PTS System AB431_01310 ENOG4105DE4 1-phosphofructokinase AB431_01320 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) AB431_01325 ENOG4105EUB pirin domain protein AB431_01340 ENOG4105C26 Dehydrogenase AB431_01350 ENOG4108UGJ Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity) AB431_01355 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr AB431_01365 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AB431_01370 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AB431_01380 ENOG4105M2Z protein tyrosine serine phosphatase AB431_01385 ENOG4105C1G acyl-Coa dehydrogenase AB431_01410 ENOG4108R86 Transcriptional regulator AB431_01430 ENOG4105CY3 ABC transporter, permease AB431_01490 ENOG4105XPP Protein of unknown function (DUF1275) AB431_01495 ENOG4105E1F short-chain dehydrogenase reductase AB431_01540 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) AB431_01555 ENOG4105E5G Alpha beta hydrolase fold AB431_01580 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB431_01585 ENOG4108FUF Transcriptional regulator, IclR family AB431_01605 ENOG4105C01 Dihydroxy-acid dehydratase AB431_01615 ENOG4105VPX protein, conserved in bacteria AB431_01620 ENOG4108XIC integral membrane protein AB431_01625 ENOG4105S7A ErfK ybiS ycfS ynhG family protein AB431_01635 ENOG4105C2C drug resistance transporter, Bcr CflA AB431_01640 ENOG4108A65 Transcriptional regulator AB431_01650 ENOG4105C9K Endothelin-converting enzyme 1 AB431_01665 ENOG4105K4P CoA-binding domain protein AB431_01675 ENOG4107WA4 MmpL domain-containing protein AB431_01695 ENOG4108TAG Histidine kinase AB431_01725 ENOG4107R13 MMPL domain protein AB431_01735 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) AB431_01750 ENOG4105C0M Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity) AB431_01760 ENOG4105E39 Enoyl-CoA hydratase AB431_01765 ENOG4105FDP GntR family transcriptional regulator AB431_01770 ENOG4105C1G acyl-Coa dehydrogenase AB431_01790 ENOG4105D2B acyl-CoA dehydrogenase AB431_01795 ENOG4105D2B acyl-CoA dehydrogenase AB431_01810 ENOG4105E2A Dehydrogenase AB431_01815 ENOG4108W9Q Endoglucanase (EC 3.2.1.4) AB431_01840 ENOG4105CEY Amp-dependent synthetase and ligase AB431_01860 ENOG4105C1G acyl-Coa dehydrogenase AB431_01865 ENOG4105D2B acyl-CoA dehydrogenase AB431_01880 ENOG4105J7D transcriptional regulator AB431_01885 ENOG4105CSU acyl-Coa dehydrogenase AB431_01900 ENOG4108M6P methyltransferase AB431_01905 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) AB431_01945 ENOG4105CEY Amp-dependent synthetase and ligase AB431_01955 ENOG41073B4 coagulation factor 5 8 type domain-containing protein AB431_01960 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) AB431_01985 ENOG4105CHR reductase AB431_01990 ENOG4105CHU acetyl-coa acetyltransferase AB431_02000 ENOG4105CSU acyl-Coa dehydrogenase AB431_02035 ENOG4105MXW flavin reductase domain protein, FMN-binding AB431_02045 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) AB431_02060 ENOG4105CR4 methylisocitrate lyase AB431_02075 ENOG4108V8F Transcriptional regulator, MarR family AB431_02085 ENOG4107R7A Allophanate hydrolase subunit 2 AB431_02090 ENOG4105P4J Allophanate hydrolase, subunit 1 AB431_02150 ENOG4105DUX Transporter AB431_02155 ENOG4105CEY Amp-dependent synthetase and ligase AB431_02160 ENOG4105D2B acyl-CoA dehydrogenase AB431_02165 ENOG4105CC9 acyl-Coa dehydrogenase AB431_02180 ENOG4105F57 Anthranilate dioxygenase reductase AB431_02190 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) AB431_02195 ENOG4108R85 Short chain dehydrogenase AB431_02220 ENOG4107FB0 transcriptional regulator DeoR family AB431_02225 ENOG4105CTS PTS system mannitol-specific AB431_02230 ENOG4105CPQ Dehydrogenase AB431_02245 ENOG4105C26 Dehydrogenase AB431_02250 ENOG4105C1G acyl-Coa dehydrogenase AB431_02255 ENOG4105C26 Dehydrogenase AB431_02275 ENOG4105CBG Sulfatase AB431_02300 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase AB431_02305 ENOG4105C0W non-ribosomal peptide synthetase AB431_02310 ENOG4105CEY Amp-dependent synthetase and ligase AB431_02370 ENOG4106K94 growth AB431_02375 ENOG41090GG peptidase S8 and S53, subtilisin, kexin, sedolisin AB431_02380 ENOG4106VYT conserved transmembrane protein AB431_02395 ENOG4105CEY Amp-dependent synthetase and ligase AB431_02400 ENOG4105D2B acyl-CoA dehydrogenase AB431_02410 ENOG4105C5I Dehydrogenase AB431_02450 ENOG4105EDW glycosyl transferase, family 39 AB431_02520 ENOG4105CS1 NAD(P)H quinone oxidoreductase AB431_02555 ENOG4105C7K acetolactate synthase AB431_02615 ENOG4105DHP deoxycytidine triphosphate deaminase AB431_02625 ENOG4105C6Y Udp-glucose 6-dehydrogenase AB431_02670 ENOG4105DF6 Fe-S oxidoreductase AB431_02720 ENOG4105DEN Luciferase family AB431_02780 ENOG4105F8J Adenylate Guanylate cyclase AB431_02790 ENOG4108093 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ AB431_02795 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) AB431_02800 ENOG4105KNI merR family transcriptional Regulator AB431_02840 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB431_02895 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) AB431_02900 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AB431_02915 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AB431_02960 ENOG4107XFB conserved TRANSMEMBRANE PROTEIN AB431_02985 ENOG4105ME7 Membrane AB431_02995 ENOG4107XZ0 Peptidase M50 AB431_03005 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis AB431_03025 ENOG4105EYF MMPL domain protein AB431_03040 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) AB431_03045 ENOG4107SPG Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR AB431_03090 ENOG4105EMU Dehydrogenase AB431_03100 ENOG4105CPU Monooxygenase AB431_03105 ENOG4105DEN Luciferase family AB431_03110 ENOG4105CPU Monooxygenase AB431_03115 ENOG4105E8R UPF0173 metal-dependent hydrolase AB431_03120 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_03135 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AB431_03155 ENOG4105MHT Transcriptional regulator, ARSR family AB431_03165 ENOG4107Q25 Serine Threonine protein kinase AB431_03170 ENOG4105CT1 (ABC) transporter AB431_03185 ENOG4108KQ5 Integrase catalytic subunit AB431_03195 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) AB431_03205 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) AB431_03220 ENOG4108PJD permease AB431_03225 ENOG4105IIU Aminopeptidase AB431_03235 ENOG4105C2W permease AB431_03255 ENOG4107RN6 Monooxygenase AB431_03265 ENOG4105DWF phosphomethylpyrimidine kinase AB431_03280 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB431_03300 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein AB431_03310 ENOG4106A3M Cytochrome p-450 AB431_03325 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AB431_03355 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) AB431_03380 ENOG4108JPZ Monovalent cation H antiporter subunit D AB431_03385 ENOG4105MKQ Monovalent cation H antiporter subunit C AB431_03390 ENOG4105D65 subunit l AB431_03440 ENOG4107JEE Short-chain dehydrogenase reductase Sdr AB431_03475 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) AB431_03495 ENOG4107EMZ glycosyl transferase family AB431_03515 ENOG41061TZ Short-chain dehydrogenase reductase Sdr AB431_03520 ENOG4105EC0 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity) AB431_03530 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) AB431_03580 ENOG4105CSR polyphosphate kinase 2 AB431_03615 ENOG4105C26 Dehydrogenase AB431_03670 ENOG4105CSR polyphosphate kinase 2 AB431_03690 ENOG4106BRA Membrane AB431_03700 ENOG4105V9F hemagglutinin AB431_03705 ENOG4105TT9 Protein of unknown function (DUF2516) AB431_03715 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) AB431_03745 ENOG4107R4N Cell wall formation (By similarity) AB431_03770 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) AB431_03775 ENOG4108YZJ Pfam:DUF2596 AB431_03785 ENOG4105BZU Histidine kinase AB431_03790 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB431_03850 ENOG41063NU Membrane AB431_03885 ENOG410900P UPF0336 protein AB431_03890 ENOG4108RXW HAD-superfamily subfamily IB hydrolase AB431_03955 ENOG4105F9F transposase AB431_03975 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) AB431_03985 ENOG410616I blue (type 1) copper domain protein AB431_04015 ENOG4108RH7 phosphoglycerate mutase AB431_04025 ENOG4107QIV Cytochrome c biogenesis protein AB431_04035 ENOG4105CRE cytochrome C AB431_04070 ENOG4107USC Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity) AB431_04080 ENOG4105D3R alkyl hydroperoxide reductase AB431_04085 ENOG4108X7C Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) AB431_04105 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB431_04140 ENOG4105MHT Transcriptional regulator, ARSR family AB431_04185 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase AB431_04190 ENOG4105PDP Short chain dehydrogenase AB431_04225 ENOG4105CEY Amp-dependent synthetase and ligase AB431_04240 ENOG4107TCW O-succinylbenzoate synthase AB431_04255 ENOG41082JN Transcriptional regulator AB431_04295 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) AB431_04315 ENOG4105E1F short-chain dehydrogenase reductase AB431_04320 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AB431_04330 ENOG4105P52 geranylgeranyl reductase AB431_04340 ENOG4105D0M Protease HtpX homolog AB431_04345 ENOG4105D8X mechanosensitive ion channel AB431_04365 ENOG4105CT3 Monooxygenase AB431_04370 ENOG4108VPT UPF0234 protein AB431_04400 ENOG4107T65 Integrase AB431_04420 ENOG4108J2P Alpha beta hydrolase fold AB431_04435 ENOG4105WH9 RNA polymerase AB431_04445 ENOG4105MC2 DSBA oxidoreductase AB431_04470 ENOG4105WH9 RNA polymerase AB431_04525 ENOG4105CM2 brancheD-chain amino acid aminotransferase AB431_04530 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase AB431_04540 ENOG4108JPM phospho-2-dehydro-3-deoxyheptonate aldolase AB431_04560 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AB431_04580 ENOG4106JDR secreted AB431_04630 ENOG4107R6F Alpha Beta Hydrolase Fold protein AB431_04635 ENOG4105BZU Histidine kinase AB431_04665 ENOG4105C57 major facilitator superfamily AB431_04695 ENOG4105C0D helicase AB431_04700 ENOG4105C9U ATP-dependent DNA helicase RecQ AB431_04710 ENOG4107QRT dEAD DEAH box helicase AB431_04800 ENOG4105EC0 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity) AB431_04850 ENOG4105CY3 ABC transporter, permease AB431_04880 ENOG4107RCI amp-dependent synthetase and ligase AB431_04965 ENOG4105VEQ Cold shock protein AB431_04970 ENOG4105C1J atp-dependent rna helicase AB431_04980 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AB431_04990 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) AB431_05040 ENOG4108IYU L-aspartate oxidase AB431_05065 ENOG4107414 GntR family transcriptional regulator AB431_05080 ENOG4105D74 hydrolase AB431_05095 ENOG4105E39 Enoyl-CoA hydratase AB431_05110 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AB431_05125 ENOG4105WDJ 50S ribosomal protein L33 AB431_05130 ENOG410900P UPF0336 protein AB431_05135 ENOG4108F01 MaoC domain protein AB431_05165 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) AB431_05170 ENOG4107ZF2 Phosphatase AB431_05200 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AB431_05230 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) AB431_05250 ENOG4105E2K Glycosyl transferase (Group 1 AB431_05255 ENOG4105C30 Nad-dependent epimerase dehydratase AB431_05260 ENOG4105C0K Gdp-mannose 4,6-dehydratase AB431_05295 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) AB431_05345 ENOG4105DKQ ROK family AB431_05355 ENOG4108VZM 50s ribosomal protein L10 AB431_05360 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) AB431_05390 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AB431_05395 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AB431_05405 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) AB431_05420 ENOG4105CSU acyl-Coa dehydrogenase AB431_05430 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein AB431_05445 ENOG4105WH1 Two component transcriptional regulator luxr family AB431_05475 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) AB431_05480 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) AB431_05485 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) AB431_05500 ENOG4108BAS reductase AB431_05505 ENOG4105C8Y Acetylornithine aminotransferase AB431_05510 ENOG4105CIK Amidinotransferase AB431_05515 ENOG4105F7P transcriptional regulator AsnC family AB431_05545 ENOG4105XDV AB431_05575 ENOG4105C57 major facilitator superfamily AB431_05590 ENOG4105EBR Carboxylesterase AB431_05635 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) AB431_05640 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) AB431_05645 ENOG4105KZR One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) AB431_05650 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity AB431_05660 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) AB431_05665 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) AB431_05675 ENOG41082SA 50s ribosomal protein l29 AB431_05680 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal AB431_05690 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) AB431_05700 ENOG4105E6M Sulphatase-modifying factor protein AB431_05710 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) AB431_05715 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) AB431_05720 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits AB431_05725 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) AB431_05730 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) AB431_05740 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) AB431_05745 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) AB431_05750 ENOG410849U 50S ribosomal protein L30 AB431_05765 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AB431_05780 ENOG4108XW1 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity) AB431_05785 ENOG4106N8J Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity) AB431_05800 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) AB431_05830 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AB431_05835 ENOG4105CIH Imidazole acetol-phosphate transaminase AB431_05850 ENOG4105C1G acyl-Coa dehydrogenase AB431_05855 ENOG4105C26 Dehydrogenase AB431_05860 ENOG4108MRH transcriptional regulatory protein AB431_05865 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism AB431_05870 ENOG4107QJT sodium dicarboxylate symporter AB431_05905 ENOG41076PI Short-chain dehydrogenase reductase Sdr AB431_05975 ENOG4105S7A ErfK ybiS ycfS ynhG family protein AB431_05995 ENOG4105H08 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AB431_06000 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AB431_06015 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr AB431_06030 ENOG4105D3W isochorismatase AB431_06045 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AB431_06050 ENOG4105CKI cobalamin synthesis protein AB431_06055 ENOG4105CNT hydrolase family 2 AB431_06070 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) AB431_06080 ENOG4105BZU Histidine kinase AB431_06085 ENOG4108ZHJ Organic hydroperoxide resistance protein AB431_06090 ENOG4105K56 Transcriptional regulator AB431_06095 ENOG4105CDA abc transporter atp-binding protein AB431_06100 ENOG4105E5Q amino acid AbC transporter AB431_06150 ENOG4105CEY Amp-dependent synthetase and ligase AB431_06235 ENOG4105CHU acetyl-coa acetyltransferase AB431_06255 ENOG4105W8D rdd domain containing protein AB431_06285 ENOG4105T1M mycothiol conjugate amidase mca AB431_06295 ENOG4105C7Z Conserved Protein AB431_06335 ENOG4105CS9 pantothenic acid kinase AB431_06345 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) AB431_06355 ENOG4108IAB Phoh family AB431_06360 ENOG4108ZJ4 polysaccharide deacetylase AB431_06370 ENOG4107U9T Pfam:Ribonuclease_BN AB431_06440 ENOG4105E6M Sulphatase-modifying factor protein AB431_06450 ENOG41061MV Arylsulfatase AB431_06470 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) AB431_06490 ENOG4105C3G gtp-binding protein AB431_06555 ENOG4108UDW Transcriptional regulator, luxr family AB431_06560 ENOG4105C5I Dehydrogenase AB431_06590 ENOG4105CHR reductase AB431_06610 ENOG4105CHU acetyl-coa acetyltransferase AB431_06625 ENOG4108Z0R Transferase AB431_06630 ENOG4105CGD Nad-dependent epimerase dehydratase AB431_06645 ENOG4108UKI Enoyl-CoA hydratase AB431_06650 ENOG410846T CoA-transferase family III AB431_06660 ENOG4105EA8 2-Nitropropane dioxygenase AB431_06690 ENOG410905P Pyridoxamine 5-phosphate AB431_06700 ENOG4107QN1 sodium solute AB431_06755 ENOG410719E cytochrome p450 AB431_06770 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_06780 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) AB431_06785 ENOG4108UJD 30S ribosomal protein S9 AB431_06795 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) AB431_06810 ENOG4105DYW oxidoreductase AB431_06820 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) AB431_06835 ENOG4105CVK Glutamate decarboxylase AB431_06850 ENOG4108KN0 Choline kinase AB431_06865 ENOG4105FDP GntR family transcriptional regulator AB431_06875 ENOG4108EMS branched-chain alpha-keto acid dehydrogenase subunit E2 AB431_06890 ENOG41080E2 ribosomal-protein-alanine acetyltransferase AB431_06895 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) AB431_06905 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) AB431_06910 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) AB431_06965 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AB431_06990 ENOG4105KIU Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) AB431_07010 ENOG4108VT4 AB431_07020 ENOG4107QVP Dehydrogenase AB431_07055 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AB431_07075 ENOG4105DU0 nucleoside hydrolase AB431_07085 ENOG4105PDP Short chain dehydrogenase AB431_07095 ENOG4105GCF PGAM AB431_07120 ENOG4105EEM helicase AB431_07125 ENOG4105C0B DNA polymerase III (alpha subunit) AB431_07145 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) AB431_07155 ENOG4105BZU Histidine kinase AB431_07160 ENOG4105GWZ Roadblock lc7 family protein AB431_07175 ENOG4107Z6C Pentapeptide repeat-containing protein AB431_07185 ENOG4105C6T cysteine synthase AB431_07215 ENOG4105IDI abc transporter atp-binding protein AB431_07220 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB431_07255 ENOG4108IQK o-acetylhomoserine AB431_07270 ENOG4105E9K Isocitrate dehydrogenase AB431_07310 ENOG4107H3J ribonuclease AB431_07315 ENOG4105DZ1 carboxypeptidase AB431_07325 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AB431_07340 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) AB431_07345 ENOG4105X7H acyl-CoA dehydrogenase AB431_07355 ENOG410900P UPF0336 protein AB431_07410 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) AB431_07435 ENOG4107QSU Phosphoglucomutase phosphomannomutase alpha beta alpha domain AB431_07445 ENOG4108KK1 membrane protein AbrB duplication AB431_07460 ENOG4107RM1 amidohydrolase AB431_07515 ENOG4105D7T ABC transporter AB431_07535 ENOG4107QRT dEAD DEAH box helicase AB431_07540 ENOG4105F8J Adenylate Guanylate cyclase AB431_07565 ENOG4108EQM faD-dependent pyridine nucleotide-disulfide oxidoreductase AB431_07575 ENOG4105CIR epoxide hydrolase AB431_07590 ENOG4105C26 Dehydrogenase AB431_07680 ENOG4108JIK carboxylase AB431_07700 ENOG4107WR6 Maf-like protein AB431_07710 ENOG4105D8K carboxyl transferase AB431_07720 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase AB431_07730 ENOG4105C1B dTDP-glucose 4-6-dehydratase AB431_07735 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase AB431_07755 ENOG4105K64 Glycosyl transferase, family 2 AB431_07760 ENOG4107RGC Glycosyl transferase, family 2 AB431_07810 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) AB431_07830 ENOG4107TB5 TRANSCRIPTIONal AB431_07865 ENOG4105K51 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) AB431_07880 ENOG4107QKV phosphomannomutase AB431_07890 ENOG4105EIP mannose-6-phosphate isomerase AB431_07905 ENOG4105CUB amino acid AB431_07910 ENOG4105EEF Alkane 1-monooxygenase AB431_07915 ENOG41084UD rubredoxin AB431_07920 ENOG4105VCQ rubredoxin AB431_07945 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB431_07970 ENOG4105D74 hydrolase AB431_07975 ENOG4107QP2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) AB431_07980 ENOG4108S7Q sigma 54 modulation protein ribosomal protein S30ea AB431_08000 ENOG4105CSR polyphosphate kinase 2 AB431_08030 ENOG4105CV8 reductase AB431_08035 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) AB431_08040 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase AB431_08045 ENOG4108RAV Conserved protein AB431_08065 ENOG4107EXU Short-chain dehydrogenase reductase Sdr AB431_08070 ENOG4105EXG Transcriptional regulator AB431_08075 ENOG4105DVW rieske (2Fe-2S) AB431_08105 ENOG4105CEY Amp-dependent synthetase and ligase AB431_08110 ENOG41076PI Short-chain dehydrogenase reductase Sdr AB431_08175 ENOG4106A3M Cytochrome p-450 AB431_08190 ENOG4106A3M Cytochrome p-450 AB431_08200 ENOG4108Z66 YbaK ebsC protein AB431_08205 ENOG4105EMN RNA polymerase sigma factor AB431_08210 ENOG4105WMN AntiSigma factor AB431_08215 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit AB431_08255 ENOG4108ZM9 phosphoglycerate mutase AB431_08270 ENOG4105C1J atp-dependent rna helicase AB431_08315 ENOG4108YIQ Alpha beta hydrolase AB431_08335 ENOG4107SVH Potassium channel protein AB431_08365 ENOG4105WBQ Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) AB431_08385 ENOG41063PX domain protein AB431_08395 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) AB431_08425 ENOG4105CH6 catalase AB431_08470 ENOG4105CRW Short chain fatty acid transporter AB431_08485 ENOG4105DUM transcriptional regulator, lysR family AB431_08490 ENOG4105D94 Major Facilitator Superfamily AB431_08570 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AB431_08575 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) AB431_08580 ENOG4107RCI amp-dependent synthetase and ligase AB431_08585 ENOG4107R13 MMPL domain protein AB431_08595 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AB431_08600 ENOG4105JZI cytochrome P450 AB431_08605 ENOG4107TXC Transcriptional regulator AB431_08640 ENOG4105E7Q Cob(II)yrinic acid a,c-diamide reductase AB431_08685 ENOG4105E39 Enoyl-CoA hydratase AB431_08690 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AB431_08705 ENOG4105M5H NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AB431_08710 ENOG4105DF2 NADH dehydrogenase subunit j AB431_08715 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AB431_08720 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) AB431_08725 ENOG4108IEH NADH dehydrogenase subunit g AB431_08740 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AB431_08745 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain AB431_08750 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AB431_08785 ENOG4105C1G acyl-Coa dehydrogenase AB431_08795 ENOG4108NUI synthase AB431_08805 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase AB431_08810 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_08845 ENOG41076PI Short-chain dehydrogenase reductase Sdr AB431_08855 ENOG4105C26 Dehydrogenase AB431_08860 ENOG41076PI Short-chain dehydrogenase reductase Sdr AB431_08875 ENOG4106A3M Cytochrome p-450 AB431_08885 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB431_08895 ENOG4107S5I aldo keto reductase AB431_08900 ENOG4105C1G acyl-Coa dehydrogenase AB431_08915 ENOG4107TK4 histidinol-phosphate phosphatase AB431_08950 ENOG4105D8X mechanosensitive ion channel AB431_08960 ENOG4105CAK Cell division ATP-binding protein ftsE AB431_08965 ENOG4107RYD Part of the ABC transporter FtsEX involved in cellular division (By similarity) AB431_08970 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) AB431_09095 ENOG4105BZU Histidine kinase AB431_09185 ENOG4105VTR Integrase AB431_09200 ENOG4105CNU cell division protein FtsK AB431_09345 ENOG4105BZU Histidine kinase AB431_09350 ENOG4105WH1 Two component transcriptional regulator luxr family AB431_09385 ENOG4107R16 Multicopper oxidase AB431_09405 ENOG41082SX arsR family transcriptional regulator AB431_09440 ENOG4105MP9 class II Aldolase AB431_09445 ENOG4105CEY Amp-dependent synthetase and ligase AB431_09455 ENOG4105CIS alcohol dehydrogenase AB431_09460 ENOG4105CAY ferredoxin--nadp reductase AB431_09545 ENOG41061TZ Short-chain dehydrogenase reductase Sdr AB431_09555 ENOG4105DVW rieske (2Fe-2S) AB431_09605 ENOG4105CT3 Monooxygenase AB431_09610 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) AB431_09620 ENOG41088PD hydrolase AB431_09650 ENOG4105E2Q 3-(3-hydroxy-phenyl)propionate hydroxylase AB431_09655 ENOG4108HUF Transporter AB431_09690 ENOG4108R85 Short chain dehydrogenase AB431_09695 ENOG4105C1G acyl-Coa dehydrogenase AB431_09700 ENOG4105CC9 acyl-Coa dehydrogenase AB431_09715 ENOG4105D22 carbon starvation protein AB431_09720 ENOG4107RYT DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity) AB431_09735 ENOG4105D2B acyl-CoA dehydrogenase AB431_09745 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase AB431_09760 ENOG4105WRB Hydrogenase assembly chaperone hypC hupF AB431_09790 ENOG4105DPX Hydrogenase, large subunit AB431_09800 ENOG4107RSS Hydrogenase accessory protein HypB AB431_09805 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) AB431_09810 ENOG4105C8H hydrogenase maturation protein Hypf AB431_09820 ENOG4105CQS hydrogenase expression formation protein HypD AB431_09865 ENOG4108YYH Nadph-dependent fmn reductase AB431_09880 ENOG4105E1F short-chain dehydrogenase reductase AB431_09895 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AB431_09925 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b AB431_09935 ENOG4108KQ5 Integrase catalytic subunit AB431_09950 ENOG4105EJ2 Transcriptional regulator AB431_09955 ENOG4107RN6 Monooxygenase AB431_09965 ENOG4105F8J Adenylate Guanylate cyclase AB431_09975 ENOG4105F8J Adenylate Guanylate cyclase AB431_09980 ENOG4105F8J Adenylate Guanylate cyclase AB431_10005 ENOG4107JEE Short-chain dehydrogenase reductase Sdr AB431_10030 ENOG4105DIA mandelate racemase muconate lactonizing AB431_10050 ENOG4105DQ4 alcohol dehydrogenase AB431_10075 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB431_10080 ENOG4108VW9 Membrane AB431_10085 ENOG4105DKW ABC transporter AB431_10115 ENOG4108V0V Pyrrolo-quinoline quinone AB431_10120 ENOG4105EVB acetyltransferase AB431_10130 ENOG4108ZHR arsR family transcriptional regulator AB431_10150 ENOG4108KQJ Type 11 methyltransferase AB431_10160 ENOG4105C10 Electron transfer flavoprotein AB431_10180 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) AB431_10260 ENOG41081AP Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) AB431_10265 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) AB431_10285 ENOG4105CMT Dihydroxyacetone kinase AB431_10290 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) AB431_10335 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr AB431_10360 ENOG4108W6C Dehydrogenase AB431_10365 ENOG4106A3M Cytochrome p-450 AB431_10370 ENOG4108RZE Tetr family transcriptional regulator AB431_10395 ENOG4108ZP8 Acetolactate synthase small subunit AB431_10400 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase AB431_10420 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AB431_10425 ENOG4105E5T Major Facilitator Superfamily AB431_10430 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase AB431_10435 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) AB431_10460 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AB431_10480 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) AB431_10495 ENOG4105C28 cystathionine AB431_10500 ENOG4105CPF Cell wall formation (By similarity) AB431_10545 ENOG4105DP4 dak2 domain fusion protein ylov AB431_10550 ENOG4105CB5 ATP-dependent DNA helicase recG AB431_10560 ENOG41081JD Transcriptional regulator AB431_10565 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AB431_10570 ENOG4105CV8 reductase AB431_10590 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) AB431_10595 ENOG4106H78 methyltransferase AB431_10600 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) AB431_10620 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) AB431_10625 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) AB431_10635 ENOG4108375 Acylphosphatase (EC 3.6.1.7) AB431_10650 ENOG4107SGM protein serine threonine phosphatase AB431_10660 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) AB431_10680 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) AB431_10710 ENOG4105DZ1 carboxypeptidase AB431_10720 ENOG4105DZ1 carboxypeptidase AB431_10730 ENOG4105K5M 30s ribosomal protein S16 AB431_10740 ENOG4107XUM An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) AB431_10770 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) AB431_10780 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) AB431_10795 ENOG4105F27 Major Facilitator AB431_10820 ENOG4105C0P Mg chelatase subunit ChlI AB431_10845 ENOG4105XTG Pfam:DUF156 AB431_10850 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB431_10855 ENOG4105CNG UPF0061 protein AB431_10870 ENOG4105CE9 30S ribosomal protein S2 AB431_10880 ENOG4105DV0 amidase (EC 3.5.1.4 AB431_10895 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) AB431_10925 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) AB431_10930 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) AB431_10940 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs AB431_10955 ENOG4105CUB amino acid AB431_10970 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) AB431_10975 ENOG4105DZP Membrane-associated zinc metalloprotease AB431_11010 ENOG4105EA8 2-Nitropropane dioxygenase AB431_11035 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) AB431_11055 ENOG4105CAQ asparagine synthetase AB431_11070 ENOG4108Z86 Glutamine amidotransferase AB431_11080 ENOG4105CHR reductase AB431_11085 ENOG41073TP transcriptional regulator AB431_11095 ENOG4105CPQ Dehydrogenase AB431_11120 ENOG4105EN6 Membrane AB431_11125 ENOG4105CH2 amidohydrolase AB431_11160 ENOG4105CHR reductase AB431_11165 ENOG4105DVW rieske (2Fe-2S) AB431_11185 ENOG4105F8J Adenylate Guanylate cyclase AB431_11210 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) AB431_11225 ENOG4108JJB ABC transporter AB431_11240 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) AB431_11255 ENOG4105DWT malate dehydrogenase (quinone) AB431_11280 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AB431_11325 ENOG4107Z1I Required for maturation of 30S ribosomal subunits (By similarity) AB431_11345 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) AB431_11350 ENOG4107ZPY Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) AB431_11355 ENOG4105SFS phosphoesterase RecJ domain protein AB431_11375 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) AB431_11420 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) AB431_11445 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) AB431_11450 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) AB431_11455 ENOG4105C1V Peptidase, M16 AB431_11475 ENOG4105DCF alanine dehydrogenase AB431_11535 ENOG4105EAH synthase AB431_11580 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) AB431_11585 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) AB431_11590 ENOG4105T0Z Conserved Protein AB431_11595 ENOG4105CEY Amp-dependent synthetase and ligase AB431_11600 ENOG4105BZU Histidine kinase AB431_11610 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB431_11615 ENOG4105CN5 Metallo-Beta-Lactamase AB431_11630 ENOG4105E3J oxidoreductase AB431_11655 ENOG4105F9F transposase AB431_11670 ENOG4108I62 cina-like protein AB431_11675 ENOG4105WBV Transcriptional regulator AB431_11690 ENOG4105MXB limonene-12-epoxide hydrolase AB431_11705 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) AB431_11715 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_11735 ENOG4105DRP amino acid AbC transporter AB431_11740 ENOG4108Q1T ABC transporter AB431_11745 ENOG4107UBR Extracellular solute-binding protein family 3 AB431_11750 ENOG4105CDA abc transporter atp-binding protein AB431_11755 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AB431_11765 ENOG4105C99 atpase involved in dna repair AB431_11770 ENOG4105PP6 Membrane AB431_11780 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) AB431_11785 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) AB431_11790 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) AB431_11800 ENOG4108J2R molybdopterin oxidoreductase AB431_11805 ENOG4105C1G acyl-Coa dehydrogenase AB431_11815 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) AB431_11900 ENOG4107QK9 Beta-lactamase AB431_11935 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) AB431_11960 ENOG4105C57 major facilitator superfamily AB431_11970 ENOG4107VEG TrkA-N domain protein AB431_11975 ENOG4105C0X amino acid AB431_11980 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) AB431_11990 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) AB431_12000 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) AB431_12010 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) AB431_12020 ENOG4107JTW chlorite dismutase AB431_12030 ENOG4105BZU Histidine kinase AB431_12035 ENOG4105BZU Histidine kinase AB431_12040 ENOG4105E0X reductase AB431_12045 ENOG4108P2G integral membrane protein AB431_12090 ENOG4105ETX regulatoR AB431_12095 ENOG4105BZU Histidine kinase AB431_12110 ENOG4107QIZ NADH dehydrogenase AB431_12120 ENOG4105BZU Histidine kinase AB431_12125 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB431_12180 ENOG4107SHJ sulfite reductase subunit b AB431_12195 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AB431_12200 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) AB431_12205 ENOG4105C7S Dehydrogenase AB431_12210 ENOG4105CPP Dehydrogenase, E1 component AB431_12265 ENOG4108IQE Amp-dependent synthetase and ligase AB431_12275 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) AB431_12310 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB431_12445 ENOG4105CHR reductase AB431_12495 ENOG4105PMW Domain of unknown function (DUF1990) AB431_12510 ENOG4105C22 threonyL-tRNA synthetase AB431_12520 ENOG4108VTU Cdp-alcohol phosphatidyltransferase AB431_12525 ENOG4107YQ3 lipid a biosynthesis lauroyl acyltransferase AB431_12530 ENOG4105E2K Glycosyl transferase (Group 1 AB431_12540 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) AB431_12545 ENOG4105C29 acyl-CoA thioesterase AB431_12550 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) AB431_12575 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase AB431_12590 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) AB431_12595 ENOG4105CSH Transporter AB431_12600 ENOG4105CDY transcriptional regulatory protein AB431_12615 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) AB431_12620 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) AB431_12625 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) AB431_12645 ENOG4105EVH UPF0753 protein AB431_12660 ENOG4105BZU Histidine kinase AB431_12665 ENOG4105E4E Thioester reductase domain-containing protein AB431_12685 ENOG4108JPW Aminotransferase AB431_12705 ENOG4107RTU Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AB431_12710 ENOG4108NY6 Extracellular solute-binding protein, family 5 AB431_12715 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) AB431_12720 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AB431_12740 ENOG4108ZR3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity) AB431_12755 ENOG4105CUT histidyl-tRNA synthetase AB431_12780 ENOG4107VGR Catalase AB431_12785 ENOG4108IV0 ABC, transporter AB431_12790 ENOG4105C0Z ABC transporter AB431_12805 ENOG41083Z3 extracellular ligand-binding receptor AB431_12835 ENOG4105EBR Carboxylesterase AB431_12845 ENOG4105D2B acyl-CoA dehydrogenase AB431_12880 ENOG4105EBR Carboxylesterase AB431_12890 ENOG4105C9M aspartyl-trna synthetase AB431_12910 ENOG4105CHU acetyl-coa acetyltransferase AB431_12915 ENOG4105KVH Transcriptional regulator AB431_12980 ENOG4105C1G acyl-Coa dehydrogenase AB431_12985 ENOG4105CHR reductase AB431_12995 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AB431_13015 ENOG4105CHR reductase AB431_13025 ENOG4107RT3 EamA-like transporter family AB431_13050 ENOG4107ZED Uncharacterised protein family UPF0047 AB431_13055 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AB431_13060 ENOG41080G3 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) AB431_13070 ENOG4105E2X shikimate dehydrogenase AB431_13105 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AB431_13110 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase AB431_13120 ENOG4105D49 3-dehydroquinate synthase AB431_13130 ENOG4105CY0 Metallo-Beta-Lactamase AB431_13145 ENOG4105DC7 peptidase M24 AB431_13150 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) AB431_13155 ENOG410803B Involved in the transcription termination process (By similarity) AB431_13170 ENOG4108KC1 acyl-Coa dehydrogenase AB431_13180 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) AB431_13185 ENOG4105CXT aspartate transcarbamylase AB431_13200 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain AB431_13205 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain AB431_13210 ENOG4105SKN orotidine 5''-phosphate decarboxylase AB431_13240 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP AB431_13245 ENOG4105F6U Short-chain dehydrogenase reductase Sdr AB431_13250 ENOG4105F8J Adenylate Guanylate cyclase AB431_13280 ENOG4108V0P LemA family AB431_13285 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) AB431_13315 ENOG4107R7Y intracellular protease Pfpi family AB431_13320 ENOG4107UWP Major facilitator superfamily MFS_1 AB431_13350 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) AB431_13355 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) AB431_13370 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) AB431_13385 ENOG4105CIE May be required for sporulation (By similarity) AB431_13395 ENOG4106PMH Extracellular solute-binding protein family 3 AB431_13400 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AB431_13405 ENOG4105BZA Phosphoglycerate kinase AB431_13410 ENOG4105CP7 Triose-phosphate isomerase AB431_13425 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) AB431_13455 ENOG4107QQX Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AB431_13465 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) AB431_13470 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein AB431_13485 ENOG4105CBC glutamate synthase AB431_13500 ENOG4107JC6 Membrane AB431_13520 ENOG4105C3K feS assembly ATPase SufC AB431_13525 ENOG4105C9B Cysteine desulfurase AB431_13530 ENOG4108UNV SUF system FeS assembly protein, NifU family AB431_13535 ENOG4105VG1 fes assembly suf system protein AB431_13555 ENOG41080RH Thioredoxin AB431_13565 ENOG4105C5H ABC transporter AB431_13575 ENOG4108Q5F Tetr family transcriptional regulator AB431_13580 ENOG4107QM5 aconitate hydratase AB431_13590 ENOG4105ZXU NLP P60 protein AB431_13600 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AB431_13615 ENOG4105CHR reductase AB431_13620 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH AB431_13625 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) AB431_13715 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) AB431_13735 ENOG4105HDK L-asparaginase AB431_13760 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AB431_13810 ENOG4105C57 major facilitator superfamily AB431_13820 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB431_13825 ENOG4105DQQ Major facilitator superfamily MFS_1 AB431_13830 ENOG4107QZF nitrite reductase NADPH large subunit AB431_13895 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AB431_13915 ENOG41064MX Tetr family transcriptional regulator AB431_13920 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) AB431_13925 ENOG41066NP positive regulation by symbiont of host immune response AB431_13970 ENOG410829K Lysine exporter protein (Lyse ygga) AB431_13975 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) AB431_13980 ENOG4105CIH Imidazole acetol-phosphate transaminase AB431_13985 ENOG4105ECC imidazole-glycerol-phosphate dehydratase AB431_13990 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) AB431_13995 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase AB431_14000 ENOG4108MWI inositol mono-phosphatase AB431_14005 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) AB431_14010 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase AB431_14015 ENOG4105DKW ABC transporter AB431_14025 ENOG4105CRQ synthase (Component I) AB431_14035 ENOG4105DK0 Indole-3-glycerol phosphate synthase AB431_14100 ENOG4107EXU Short-chain dehydrogenase reductase Sdr AB431_14110 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) AB431_14125 ENOG4106A3M Cytochrome p-450 AB431_14140 ENOG41061TZ Short-chain dehydrogenase reductase Sdr AB431_14145 ENOG4105CHR reductase AB431_14150 ENOG4107GJV short-chain dehydrogenase reductase AB431_14165 ENOG4105CHR reductase AB431_14195 ENOG4108BAS reductase AB431_14205 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) AB431_14235 ENOG4106A3M Cytochrome p-450 AB431_14240 ENOG4105CEY Amp-dependent synthetase and ligase AB431_14250 ENOG4108XG4 DNA-binding transcriptional regulator AB431_14265 ENOG4108KC2 acyl-Coa dehydrogenase AB431_14280 ENOG4105X7H acyl-CoA dehydrogenase AB431_14295 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_14360 ENOG4105D2B acyl-CoA dehydrogenase AB431_14370 ENOG4105C1G acyl-Coa dehydrogenase AB431_14375 ENOG4105D2B acyl-CoA dehydrogenase AB431_14380 ENOG4105CEY Amp-dependent synthetase and ligase AB431_14385 ENOG41076PI Short-chain dehydrogenase reductase Sdr AB431_14405 ENOG4105CHR reductase AB431_14425 ENOG4105E39 Enoyl-CoA hydratase AB431_14435 ENOG4105CC9 acyl-Coa dehydrogenase AB431_14440 ENOG4105CGU Enoyl-CoA hydratase AB431_14450 ENOG4105CGU Enoyl-CoA hydratase AB431_14455 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr AB431_14505 ENOG4105X7H acyl-CoA dehydrogenase AB431_14550 ENOG4108IG5 Transcriptional regulator AB431_14560 ENOG4105GMT ATPase associated with various cellular activities aaa_5 AB431_14565 ENOG4105FAE von Willebrand factor, type A AB431_14600 ENOG4105DHM ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity) AB431_14625 ENOG4105E5F proteasome AB431_14635 ENOG4105KPK Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity) AB431_14640 ENOG4105F7N Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity) AB431_14660 ENOG4105DVV Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity) AB431_14670 ENOG4107TMB Transcriptional regulator AB431_14715 ENOG4108RG3 short-chain dehydrogenase reductase AB431_14770 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AB431_14790 ENOG4105CTK cobaltochelatase, cobn subunit AB431_14820 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) AB431_14825 ENOG4105Q70 AB431_14835 ENOG4105C9U ATP-dependent DNA helicase RecQ AB431_14840 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AB431_14855 ENOG4105EBR Carboxylesterase AB431_14895 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family AB431_14900 ENOG4105C6Z Gluconate AB431_14935 ENOG4107QVI Methyltransferase, type 11 AB431_14940 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) AB431_14955 ENOG4108RWI nicotinamidase AB431_14970 ENOG4108SVW integral membrane protein AB431_14975 ENOG4105DHT Metal Dependent Phosphohydrolase AB431_14990 ENOG4105D38 putrescine abc transporter AB431_14995 ENOG4105F38 ABC transporter, permease AB431_15010 ENOG4105C1G acyl-Coa dehydrogenase AB431_15025 ENOG4105CY3 ABC transporter, permease AB431_15070 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein AB431_15085 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein AB431_15135 ENOG4105CEY Amp-dependent synthetase and ligase AB431_15140 ENOG4105C1G acyl-Coa dehydrogenase AB431_15150 ENOG4105H9W Short-chain dehydrogenase reductase Sdr AB431_15190 ENOG4107S2E monooxygenase AB431_15205 ENOG4105CHR reductase AB431_15210 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_15235 ENOG4105H37 Glyoxalase Bleomycin resistance protein (Dioxygenase AB431_15245 ENOG4107S2E monooxygenase AB431_15255 ENOG4105BZU Histidine kinase AB431_15260 ENOG4105D64 Mechanosensitive ion channel AB431_15265 ENOG4105D5U fad dependent oxidoreductase AB431_15285 ENOG4107AQZ Membrane AB431_15290 ENOG4107RCC Major Facilitator Superfamily AB431_15400 ENOG4105VEQ Cold shock protein AB431_15420 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) AB431_15430 ENOG4108SBK dioxygenase, subunit beta AB431_15490 ENOG4105CHU acetyl-coa acetyltransferase AB431_15495 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_15500 ENOG4105CPQ Dehydrogenase AB431_15515 ENOG4108US0 Transcription regulator that can specifically activate or repress expression of target genes (By similarity) AB431_15530 ENOG4105CIR epoxide hydrolase AB431_15585 ENOG410626B catechol 1,2-dioxygenase AB431_15620 ENOG4105CPQ Dehydrogenase AB431_15630 ENOG4105FUY alpha subunit AB431_15640 ENOG4105C26 Dehydrogenase AB431_15695 ENOG4105FUY alpha subunit AB431_15700 ENOG4107258 Transcriptional regulator AB431_15715 ENOG4107QNJ CoA-transferase subunit B AB431_15725 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase AB431_15730 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase AB431_15735 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta AB431_15745 ENOG4108FUF Transcriptional regulator, IclR family AB431_15750 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB431_15755 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) AB431_15775 ENOG4106DX9 Aromatic-ring-hydroxylating dioxygenase beta subunit AB431_15780 ENOG4105FUY alpha subunit AB431_15785 ENOG4108QJ2 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase AB431_15825 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB431_15830 ENOG4108VWS Yaeq family AB431_15850 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) AB431_15865 ENOG4105VEQ Cold shock protein AB431_15890 ENOG4108WKN secreted protein AB431_15900 ENOG4105BZU Histidine kinase AB431_15905 ENOG4105KIR Thiol-disulfide oxidoreductase dcc AB431_15915 ENOG4105CHU acetyl-coa acetyltransferase AB431_15925 ENOG4105CEP NADH dehydrogenase AB431_15955 ENOG4107R13 MMPL domain protein AB431_15985 ENOG4106HB6 Alpha beta hydrolase AB431_15995 ENOG4105CHR reductase AB431_16005 ENOG4105C0H protease AB431_16010 ENOG4108V1T peptidylprolyl cis-trans isomerase AB431_16045 ENOG4105BZM domain protein AB431_16115 ENOG4105ZXU NLP P60 protein AB431_16135 ENOG4105C26 Dehydrogenase AB431_16140 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AB431_16165 ENOG4105CPQ Dehydrogenase AB431_16210 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) AB431_16250 ENOG4107S5I aldo keto reductase AB431_16270 ENOG4105C3R Methionine synthase AB431_16280 ENOG4107ZR7 Membrane AB431_16285 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) AB431_16290 ENOG4105F4R Transcriptional regulator mode AB431_16310 ENOG4105BZU Histidine kinase AB431_16425 ENOG4105PP6 Membrane AB431_16435 ENOG4108RXW HAD-superfamily subfamily IB hydrolase AB431_16485 ENOG4105CHR reductase AB431_16495 ENOG4106A3M Cytochrome p-450 AB431_16575 ENOG4105WWF Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) AB431_16585 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_16615 ENOG4107R5I Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) AB431_16640 ENOG4108MJN Glycosyl Transferase AB431_16650 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) AB431_16660 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr AB431_16670 ENOG4105MXB limonene-12-epoxide hydrolase AB431_16700 ENOG4105C5F glutamine synthetase AB431_16715 ENOG4108UQY Iron-storage protein AB431_16725 ENOG4108UKI Enoyl-CoA hydratase AB431_16790 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) AB431_16800 ENOG4105DYW oxidoreductase AB431_16825 ENOG4105CHU acetyl-coa acetyltransferase AB431_16850 ENOG4107QRI Phosphoketolase AB431_16875 ENOG4105Y3U Transglycosylase-associated protein AB431_16900 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_16915 ENOG4108TAG Histidine kinase AB431_16920 ENOG4105MT3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) AB431_16925 ENOG4107S16 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) AB431_16935 ENOG4105CQM Urea amidohydrolase subunit alpha AB431_16940 ENOG4105KI2 Urea amidohydrolase subunit beta AB431_16945 ENOG4108YZ9 Urea amidohydrolase subunit gamma AB431_16970 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) AB431_16980 ENOG4105C37 (CBS) domain AB431_16985 ENOG4107UAX integral membrane protein AB431_16995 ENOG4107QP3 malate synthase g AB431_17010 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor AB431_17035 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) AB431_17075 ENOG4107EFR Flavocytochrome c AB431_17100 ENOG4105CJP fad dependent oxidoreductase AB431_17105 ENOG4105CKD glutathione-regulated potassium-efflux system protein AB431_17120 ENOG4105EBR Carboxylesterase AB431_17125 ENOG410814C multidrug resistance protein AB431_17130 ENOG410814C multidrug resistance protein AB431_17160 ENOG4105F8J Adenylate Guanylate cyclase AB431_17200 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) AB431_17210 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB431_17220 ENOG4108RZE Tetr family transcriptional regulator AB431_17230 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein AB431_17295 ENOG4105CSH Transporter AB431_17300 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) AB431_17315 ENOG4105D2B acyl-CoA dehydrogenase AB431_17320 ENOG4105CC9 acyl-Coa dehydrogenase AB431_17325 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) AB431_17335 ENOG4105CC9 acyl-Coa dehydrogenase AB431_17340 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_17345 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr AB431_17350 ENOG4107R5W Monooxygenase AB431_17360 ENOG4105CHR reductase AB431_17375 ENOG4105CEY Amp-dependent synthetase and ligase AB431_17385 ENOG4105CEY Amp-dependent synthetase and ligase AB431_17400 ENOG4105CUB amino acid AB431_17445 ENOG4105C7N Xanthine uracil vitamin C permease AB431_17505 ENOG4105C85 amino acid AB431_17510 ENOG4105DNP FAD linked oxidase domain protein AB431_17535 ENOG4105MKU Transcriptional regulator AB431_17545 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_17560 ENOG4107GD3 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity) AB431_17600 ENOG41082BM Transcriptional regulator, arsr family AB431_17610 ENOG41066UM arsR family transcriptional regulator AB431_17615 ENOG4108KQ5 Integrase catalytic subunit AB431_17675 ENOG4105VTR Integrase AB431_17700 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) AB431_17705 ENOG4105CAT Cytidine monophosphate kinase AB431_17715 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) AB431_17720 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) AB431_17735 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) AB431_17740 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) AB431_17775 ENOG4105DSU hydrolase AB431_17805 ENOG4108VX5 3-methyladenine DNA glycosylase AB431_17810 ENOG4105CJ1 ABC, transporter AB431_17830 ENOG4105W49 UPF0434 protein AB431_17845 ENOG4105C5H ABC transporter AB431_17855 ENOG4105CDH Citrulline--aspartate ligase AB431_17865 ENOG4105DBV ornithine carbamoyltransferase AB431_17870 ENOG4105C8Y Acetylornithine aminotransferase AB431_17875 ENOG4105CAS nag kinase AB431_17880 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) AB431_17890 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) AB431_17895 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) AB431_17900 ENOG4105CBC glutamate synthase AB431_17940 ENOG4105C1G acyl-Coa dehydrogenase AB431_17945 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding AB431_17950 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit AB431_17955 ENOG4105C7W Xanthine dehydrogenase AB431_17965 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) AB431_17970 ENOG41084BS 50S ribosomal protein L35 AB431_17985 ENOG4105CRK lysyL-tRNA synthetase AB431_18000 ENOG4107GJV short-chain dehydrogenase reductase AB431_18010 ENOG4105C5X domain protein AB431_18035 ENOG4105D7N magnesium and cobalt transport protein CorA AB431_18050 ENOG4108UN4 phage SPO1 DNA polymerase-related protein AB431_18070 ENOG4105KT7 mgtC SapB transporter AB431_18140 ENOG41063C6 UPF0235 protein AB431_18150 ENOG4108IV0 ABC, transporter AB431_18155 ENOG4105C0Z ABC transporter AB431_18160 ENOG4105CF8 branched-chain amino acid ABC transporter, permease AB431_18165 ENOG4105C32 Amino acid ABC transporter (Permease) AB431_18185 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain AB431_18225 ENOG4105EAB amino acid AbC transporter AB431_18235 ENOG4105C4M (Ubiquinol oxidase) subunit I AB431_18240 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AB431_18245 ENOG4108JJ9 ABC, transporter AB431_18250 ENOG4108JJ8 (ABC) transporter AB431_18265 ENOG4105C29 acyl-CoA thioesterase AB431_18280 ENOG4105CBC glutamate synthase AB431_18370 ENOG4108J5G 6-phosphogluconate dehydrogenase AB431_18390 ENOG4105CC9 acyl-Coa dehydrogenase AB431_18395 ENOG4105C1G acyl-Coa dehydrogenase AB431_18400 ENOG4108BAS reductase AB431_18405 ENOG4105C8N cysteinyl-tRNA synthetase AB431_18410 ENOG4108RM3 Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I- 1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F- 6-P)) and AMP in vitro, but this might has no significance in vivo AB431_18450 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) AB431_18460 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) AB431_18485 ENOG4105CPT Alpha beta hydrolase AB431_18500 ENOG4105SHT UspA domain-containing protein AB431_18515 ENOG4105JN3 extra-cytoplasmic solute receptor family protein AB431_18520 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism AB431_18525 ENOG4108MRH transcriptional regulatory protein AB431_18530 ENOG4107SCA Formamidase (EC 3.5.1.49) AB431_18535 ENOG4105KME endoribonuclease L-psp AB431_18550 ENOG4105CHR reductase AB431_18555 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AB431_18585 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) AB431_18610 ENOG4105DFU Cell wall formation (By similarity) AB431_18615 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) AB431_18625 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) AB431_18630 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) AB431_18640 ENOG4105CJN penicillin-binding protein AB431_18650 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) AB431_18670 ENOG4105R14 (LipO)protein AB431_18680 ENOG41090CE integral membrane protein AB431_18685 ENOG4105KYH transcriptional regulatory protein AB431_18700 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase AB431_18715 ENOG4108VJY integral membrane protein AB431_18730 ENOG4105D0U Arsenite-activated ATPase (ArsA) AB431_18785 ENOG4105CCU oxidase (Subunit III) AB431_18865 ENOG410813T Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) AB431_18880 ENOG4105CM2 brancheD-chain amino acid aminotransferase AB431_18915 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) AB431_18920 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) AB431_18945 ENOG4105C5F glutamine synthetase AB431_18950 ENOG4105BZU Histidine kinase AB431_18960 ENOG4105MGM doxx family AB431_18975 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) AB431_18980 ENOG4105C5F glutamine synthetase AB431_19000 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) AB431_19005 ENOG4108UKI Enoyl-CoA hydratase AB431_19050 ENOG4105C3M thioredoxin reductase AB431_19055 ENOG4105CVJ phosphoglycerate mutase AB431_19085 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) AB431_19135 ENOG4105MKU Transcriptional regulator AB431_19140 ENOG41076PI Short-chain dehydrogenase reductase Sdr AB431_19160 ENOG4108RZE Tetr family transcriptional regulator AB431_19170 ENOG4108M8W Monooxygenase AB431_19180 ENOG4108M8W Monooxygenase AB431_19190 ENOG4105EA8 2-Nitropropane dioxygenase AB431_19240 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) AB431_19250 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AB431_19255 ENOG41082KT Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) AB431_19260 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AB431_19365 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AB431_19385 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) AB431_19410 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AB431_19440 ENOG4105DEF Extracellular solute-binding protein, family 5 AB431_19450 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB431_19455 ENOG4108JQ6 ABC transporter AB431_19515 ENOG4107YPT transcriptional regulator AB431_19535 ENOG4107T8P acyl-Coa dehydrogenase AB431_19540 ENOG4105FBW Monooxygenase AB431_19550 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AB431_19555 ENOG4106FTQ Taurine ABC transporter, periplasmic AB431_19620 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AB431_19665 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component AB431_19670 ENOG4105DRS transport system, permease AB431_19695 ENOG4105DXB Major Facilitator superfamily AB431_19700 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) AB431_19705 ENOG4105FFC UPF0187 protein AB431_19715 ENOG4105C1G acyl-Coa dehydrogenase AB431_19720 ENOG4105BZU Histidine kinase AB431_19730 ENOG4105CCU oxidase (Subunit III) AB431_19760 ENOG4105CY0 Metallo-Beta-Lactamase AB431_19785 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) AB431_19805 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) AB431_19825 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) AB431_19830 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) AB431_19845 ENOG4107SCK Monooxygenase AB431_19850 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) AB431_19865 ENOG4107VNR Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) AB431_19880 ENOG4106A3M Cytochrome p-450 AB431_19885 ENOG4105WH1 Two component transcriptional regulator luxr family AB431_19895 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) AB431_19900 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) AB431_19910 ENOG4105BZU Histidine kinase AB431_19915 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB431_19920 ENOG4105CHH sulfate transporter AB431_19935 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AB431_19965 ENOG4105ECW sulfate abc transporter AB431_19970 ENOG4108I5D sulfate abc transporter AB431_19975 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein AB431_19985 ENOG4105BZP glycoside hydrolase 15-related AB431_19995 ENOG4105C2C drug resistance transporter, Bcr CflA AB431_20010 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) AB431_20020 ENOG4107TPS domain protein AB431_20035 ENOG4105CUB amino acid AB431_20075 ENOG4105CPC Aldo Keto reductase AB431_20090 ENOG4105CFQ glutamine synthetase AB431_20095 ENOG4107XDQ Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) AB431_20120 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) AB431_20135 ENOG4105KQC Competence protein AB431_20145 ENOG4108YYC ycei family AB431_20155 ENOG4108TZC AB431_20160 ENOG4105CVJ phosphoglycerate mutase AB431_20165 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) AB431_20170 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) AB431_20185 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB431_20190 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) AB431_20210 ENOG4108RVA ribokinase AB431_20215 ENOG4105E39 Enoyl-CoA hydratase AB431_20225 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) AB431_20240 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) AB431_20245 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control AB431_20250 ENOG4105K46 50S ribosomal protein l27 AB431_20255 ENOG410826X This protein binds to 23S rRNA in the presence of protein L20 (By similarity) AB431_20260 ENOG4105C03 ribonuclease AB431_20265 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) AB431_20275 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase AB431_20280 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) AB431_20285 ENOG4105EG6 Saccharopine dehydrogenase AB431_20290 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein AB431_20310 ENOG41080AZ Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) AB431_20315 ENOG4105DQU oxidoreductase, subunit beta AB431_20320 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein AB431_20325 ENOG4108RVA ribokinase AB431_20330 ENOG4105ETE Transcriptional regulator (LacI family AB431_20340 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) AB431_20350 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) AB431_20355 ENOG4105C2J ABC transporter AB431_20360 ENOG41062B0 ABC transporter, permease AB431_20370 ENOG4105ETE Transcriptional regulator (LacI family AB431_20375 ENOG4105CK5 oxidoreductase AB431_20395 ENOG4105FDP GntR family transcriptional regulator AB431_20410 ENOG4105DH8 myo-inositol catabolism AB431_20415 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) AB431_20425 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) AB431_20430 ENOG4105F0H myo-inositol catabolism protein AB431_20465 ENOG4105C5Q Transcriptional regulator AB431_20505 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) AB431_20520 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation AB431_20630 ENOG4105MC2 DSBA oxidoreductase AB431_20645 ENOG4109057 AB431_20665 ENOG4105CG3 alpha amylase, catalytic region AB431_20685 ENOG4105C7I Dehydrogenase AB431_20825 ENOG4107R3N Filamentation induced by cAMP protein fic AB431_20855 ENOG4106F60 Histidine kinase AB431_20860 ENOG4105ETX regulatoR AB431_20875 ENOG4108KQ5 Integrase catalytic subunit AB431_20890 ENOG4106A3M Cytochrome p-450 AB431_20895 ENOG4105CHR reductase AB431_20910 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AB431_20925 ENOG4105CHR reductase AB431_20940 ENOG41061TZ Short-chain dehydrogenase reductase Sdr AB431_20965 ENOG4105CHR reductase AB431_21000 ENOG4108KPJ rna polymerase sigma factor AB431_21010 ENOG4107REC cytoplasmic protein AB431_21015 ENOG4107R1Q Membrane protein FdrA AB431_21020 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) AB431_21050 ENOG4107RN0 branched-chain alpha-keto acid dehydrogenase subunit E2 AB431_21075 ENOG4105C1G acyl-Coa dehydrogenase AB431_21085 ENOG4107QX3 carboxylase AB431_21115 ENOG4105E1F short-chain dehydrogenase reductase AB431_21120 ENOG4105D7A ATP-binding protein AB431_21125 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) AB431_21160 ENOG4105D8V Glucose sorbosone dehydrogenase AB431_21175 ENOG4105CN9 Peptidase m42 family protein AB431_21180 ENOG4105C54 Major Facilitator superfamily AB431_21200 ENOG4105NPE arsR family transcriptional regulator AB431_21205 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase AB431_21210 ENOG4105IBS Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) AB431_21220 ENOG4108WKN secreted protein AB431_21225 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AB431_21230 ENOG4107TYH extracellular solute-binding protein family 1 AB431_21235 ENOG4105D81 ABC transporter, permease AB431_21240 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component AB431_21255 ENOG4105C1G acyl-Coa dehydrogenase AB431_21260 ENOG4107S4F acyltransferase, ws dgat mgat AB431_21265 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic AB431_21320 ENOG4105CHR reductase AB431_21360 ENOG4105CEY Amp-dependent synthetase and ligase AB431_21415 ENOG4106A3M Cytochrome p-450 AB431_21420 ENOG41076PI Short-chain dehydrogenase reductase Sdr AB431_21425 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB431_21440 ENOG4108QIU Dehydrogenase AB431_21450 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein AB431_21455 ENOG4105MI0 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity) AB431_21465 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) AB431_21475 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein AB431_21480 ENOG4105CEY Amp-dependent synthetase and ligase AB431_21485 ENOG4105E39 Enoyl-CoA hydratase AB431_21505 ENOG4105DYW oxidoreductase AB431_21525 ENOG4105CMR udp-glucose 4-epimerase AB431_21530 ENOG4108KEZ Dehydrogenase AB431_21555 ENOG4105CHU acetyl-coa acetyltransferase AB431_21635 ENOG4105CY3 ABC transporter, permease AB431_21650 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_21660 ENOG4105CHR reductase AB431_21665 ENOG41076PI Short-chain dehydrogenase reductase Sdr AB431_21685 ENOG4105CC9 acyl-Coa dehydrogenase AB431_21690 ENOG4105C1G acyl-Coa dehydrogenase AB431_21720 ENOG4107QIZ NADH dehydrogenase AB431_21745 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AB431_21750 ENOG4106A3M Cytochrome p-450 AB431_21770 ENOG4105C1G acyl-Coa dehydrogenase AB431_21775 ENOG4105CHU acetyl-coa acetyltransferase AB431_21780 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_21800 ENOG4105DVW rieske (2Fe-2S) AB431_21810 ENOG4105CPN adenine deaminase AB431_21820 ENOG4105D2B acyl-CoA dehydrogenase AB431_21825 ENOG4105D2B acyl-CoA dehydrogenase AB431_21840 ENOG4105CHU acetyl-coa acetyltransferase AB431_21855 ENOG4105CC9 acyl-Coa dehydrogenase AB431_21860 ENOG4105D2B acyl-CoA dehydrogenase AB431_21875 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_21880 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_21910 ENOG4105K9H YciI-like protein AB431_22025 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) AB431_22035 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) AB431_22070 ENOG4105KEN Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) AB431_22075 ENOG4107RKP Nicotinate phosphoribosyltransferase AB431_22100 ENOG4105EP6 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity) AB431_22105 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) AB431_22120 ENOG4105CHU acetyl-coa acetyltransferase AB431_22135 ENOG4105CYV Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity) AB431_22140 ENOG4105F8J Adenylate Guanylate cyclase AB431_22180 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) AB431_22200 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) AB431_22205 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) AB431_22210 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) AB431_22215 ENOG4108T62 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) AB431_22225 ENOG410679R F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) AB431_22230 ENOG4107RAZ it plays a direct role in the translocation of protons across the membrane (By similarity) AB431_22240 ENOG4105ESV Glycosyl transferase, family 4 AB431_22250 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AB431_22255 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) AB431_22265 ENOG4105J5T Amp-dependent synthetase and ligase AB431_22270 ENOG4108IG5 Transcriptional regulator AB431_22285 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) AB431_22290 ENOG4107R5I Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) AB431_22295 ENOG4105D6E homoserine dehydrogenase AB431_22300 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) AB431_22305 ENOG4105C75 arginyL-tRNA synthetase AB431_22340 ENOG4107RCI amp-dependent synthetase and ligase AB431_22390 ENOG4105EXC Acyl-transferase AB431_22395 ENOG4105EXC Acyl-transferase AB431_22420 ENOG4107EMZ glycosyl transferase family AB431_22425 ENOG4108I2E Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) AB431_22430 ENOG4105C6Y Udp-glucose 6-dehydrogenase AB431_22450 ENOG4105EXC Acyl-transferase AB431_22555 ENOG4108JA1 polyketide synthase AB431_22560 ENOG4107QKG PfaD family AB431_22605 ENOG4105DMF Dehydrogenase AB431_22660 ENOG4105C11 sulfate adenylyltransferase), subunit 2 AB431_22705 ENOG4107T8P acyl-Coa dehydrogenase AB431_22745 ENOG4105BZ1 (ABC) transporter AB431_22775 ENOG4105F8J Adenylate Guanylate cyclase AB431_22795 ENOG4105DEN Luciferase family AB431_22810 ENOG4105CQB FAD linked oxidase domain protein AB431_22815 ENOG4105CIR epoxide hydrolase AB431_22825 ENOG4105DVW rieske (2Fe-2S) AB431_22870 ENOG4107QYX exodeoxyribonuclease v alpha AB431_22875 ENOG4105CQB FAD linked oxidase domain protein AB431_22895 ENOG4105CNV Aldolase AB431_22900 ENOG4105CHR reductase AB431_22905 ENOG4107RN6 Monooxygenase AB431_22920 ENOG4107EXU Short-chain dehydrogenase reductase Sdr AB431_22945 ENOG4105C2C drug resistance transporter, Bcr CflA AB431_22955 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 AB431_22985 ENOG4105D7N magnesium and cobalt transport protein CorA AB431_23035 ENOG4105CJW magnesium transporter AB431_23055 ENOG4105UTW Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) AB431_23060 ENOG4105C0H protease AB431_23065 ENOG4106684 AB431_23075 ENOG4107ZBN O-methyltransferase AB431_23080 ENOG4108X07 Tetr family transcriptional regulator AB431_23085 ENOG4105CIG ABC transporter AB431_23090 ENOG4105DIM ABC transporter AB431_23105 ENOG4108IND Tetr family transcriptional regulator AB431_23125 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) AB431_23130 ENOG4107QPH glycogen) synthase AB431_23135 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AB431_23145 ENOG4105C3Q Glycosyl transferase, family 2 AB431_23170 ENOG4107R4C succinyl-diaminopimelate desuccinylase AB431_23190 ENOG4105CEY Amp-dependent synthetase and ligase AB431_23215 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) AB431_23235 ENOG4108TJN glycosyl transferase group 1 AB431_23255 ENOG41062BK proline dehydrogenase AB431_23260 ENOG4105C26 Dehydrogenase AB431_23280 ENOG4108Z4U Ferredoxin AB431_23300 ENOG4108KZ5 Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity) AB431_23360 ENOG4105EC2 ftsk spoIIIe AB431_23370 ENOG41090GG peptidase S8 and S53, subtilisin, kexin, sedolisin AB431_23415 ENOG4108ZT0 50S ribosomal protein l17 AB431_23420 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AB431_23425 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) AB431_23430 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) AB431_23435 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits AB431_23445 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) AB431_23450 ENOG4108JU3 Alkyl hydroperoxide reductase AB431_23455 ENOG4105CUX Signal transduction histidine kinase AB431_23475 ENOG4105C1B dTDP-glucose 4-6-dehydratase AB431_23485 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) AB431_23490 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) AB431_23495 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) AB431_23530 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) AB431_23545 ENOG410650H (LipO)protein AB431_23550 ENOG4105DBE peroxidase AB431_23555 ENOG4105DXN mazG family AB431_23570 ENOG4108IG5 Transcriptional regulator AB431_23580 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) AB431_23605 ENOG4107XT7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) AB431_23635 ENOG4107RCI amp-dependent synthetase and ligase AB431_23640 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) AB431_23645 ENOG4107QPV Serine Threonine protein kinase AB431_23650 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) AB431_23655 ENOG4106839 domain protein AB431_23660 ENOG4105F8V Hydrolase, tatD family AB431_23675 ENOG4108KPJ rna polymerase sigma factor AB431_23700 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_23715 ENOG4105F95 Monooxygenase AB431_23720 ENOG4107R5W Monooxygenase AB431_23730 ENOG4105CEU Arginine dihydrolase AB431_23735 ENOG4108Z4X TRANSCRIPTIONal AB431_23760 ENOG4105KAV tspo and mbr like protein AB431_23775 ENOG4105F9E Shikimate 5-dehydrogenase AB431_23780 ENOG410870F Cyclic nucleotide-binding protein AB431_23790 ENOG4105CHR reductase AB431_23795 ENOG4107SCK Monooxygenase AB431_23865 ENOG4105GMT ATPase associated with various cellular activities aaa_5 AB431_23935 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AB431_23940 ENOG41080UU 5-formyltetrahydrofolate cyclo-ligase AB431_23965 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AB431_23970 ENOG4105C0H protease AB431_23985 ENOG41067C8 50S ribosomal protein L32 AB431_24000 ENOG4107QX3 carboxylase AB431_24015 ENOG41060WC Enoyl-CoA hydratase AB431_24030 ENOG4107KWJ von Willebrand factor, type A AB431_24060 ENOG41078VV 34 kDa antigenic protein AB431_24065 ENOG4105FBW Monooxygenase AB431_24085 ENOG4105CMV Succinyl-CoA synthetase subunit beta AB431_24090 ENOG4105DR5 peptidase AB431_24100 ENOG410841Q phosphoesterase PA-phosphatase related protein AB431_24115 ENOG4105EXC Acyl-transferase AB431_24140 ENOG41082T9 Membrane AB431_24150 ENOG4107UWP Major facilitator superfamily MFS_1 AB431_24180 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AB431_24195 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) AB431_24205 ENOG4105DQE DNA ligase AB431_24215 ENOG4105FDF Could be involved in DNA repair (By similarity) AB431_24255 ENOG4105K6V RNA polymerase AB431_24260 ENOG4105RSG Anti-sigma-K factor RskA AB431_24265 ENOG4106PVI ATP-dependent carboxylate-amine ligase (By similarity) AB431_24270 ENOG4108M8W Monooxygenase AB431_24305 ENOG4105CHU acetyl-coa acetyltransferase AB431_24340 ENOG4105C5H ABC transporter AB431_24395 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic AB431_24400 ENOG4107S1E Beta-lactamase AB431_24430 ENOG4105BZ1 (ABC) transporter AB431_24435 ENOG4105BZ1 (ABC) transporter AB431_24450 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr AB431_24490 ENOG4105CHR reductase AB431_24500 ENOG41081K0 peptidylprolyl cis-trans isomerase AB431_24505 ENOG4105FDP GntR family transcriptional regulator AB431_24510 ENOG4105CHR reductase AB431_24515 ENOG4105KKJ Aminoglycoside phosphotransferase AB431_24535 ENOG4108US0 Transcription regulator that can specifically activate or repress expression of target genes (By similarity) AB431_24540 ENOG4105C57 major facilitator superfamily AB431_24565 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) AB431_24590 ENOG4105URP P-aminobenzoate N-oxygenase AurF AB431_24595 ENOG4107R8H Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) AB431_24645 ENOG4105CHF Glutathione S-transferase AB431_24650 ENOG4105VEQ Cold shock protein AB431_24655 ENOG410901E Membrane AB431_24660 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AB431_24680 ENOG4108RIR Molybdenum cofactor biosynthesis protein AB431_24700 ENOG4105CFI type iii restriction protein res subunit AB431_24710 ENOG4105CHU acetyl-coa acetyltransferase AB431_24720 ENOG4108M8W Monooxygenase AB431_24735 ENOG4105CHU acetyl-coa acetyltransferase AB431_24750 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AB431_24755 ENOG4105C26 Dehydrogenase AB431_24760 ENOG4107RR1 TRANSCRIPTIONal AB431_24780 ENOG410846T CoA-transferase family III AB431_24860 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB431_24875 ENOG4105D8K carboxyl transferase AB431_24905 ENOG4105MKU Transcriptional regulator AB431_24915 ENOG4107S2E monooxygenase AB431_24920 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AB431_24925 ENOG4108K3M Rieske [2Fe-2S] domain AB431_24935 ENOG4107YB1 Trehalose corynomycolyl transferase AB431_24955 ENOG410846T CoA-transferase family III AB431_24970 ENOG4108J2R molybdopterin oxidoreductase AB431_24980 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_24995 ENOG4105X7H acyl-CoA dehydrogenase AB431_25005 ENOG4105X7H acyl-CoA dehydrogenase AB431_25035 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB431_25060 ENOG4105E39 Enoyl-CoA hydratase AB431_25065 ENOG4105C6F GntR Family Transcriptional Regulator AB431_25070 ENOG4105E39 Enoyl-CoA hydratase AB431_25075 ENOG4105E39 Enoyl-CoA hydratase AB431_25090 ENOG4105CEY Amp-dependent synthetase and ligase AB431_25095 ENOG4105CEY Amp-dependent synthetase and ligase AB431_25110 ENOG4105C1G acyl-Coa dehydrogenase AB431_25115 ENOG4105CHU acetyl-coa acetyltransferase AB431_25125 ENOG4105C1G acyl-Coa dehydrogenase AB431_25130 ENOG4108BAS reductase AB431_25140 ENOG4105H3G oxidoreductase AB431_25150 ENOG4105CHR reductase AB431_25155 ENOG4105CHR reductase AB431_25160 ENOG4108JGH Tetr family transcriptional regulator AB431_25170 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB431_25200 ENOG4105D3Q Sugar transferase AB431_25240 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) AB431_25260 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) AB431_25265 ENOG4107NHD transcriptional regulator AB431_25285 ENOG4105KHC sulfurtransferase AB431_25290 ENOG4105PKJ carbohydrate binding AB431_25320 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) AB431_25325 ENOG4105CXB phosphoribosylaminoimidazole synthetase AB431_25340 ENOG4105CGD Nad-dependent epimerase dehydratase AB431_25390 ENOG4105DFM M18 family aminopeptidase AB431_25395 ENOG4105EZR dyp-type peroxidase family protein AB431_25405 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I AB431_25410 ENOG410839H phosphoribosylformylglycinamidine synthase AB431_25425 ENOG4105CHR reductase AB431_25460 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) AB431_25490 ENOG4105C83 adenylosuccinate lyase AB431_25530 ENOG4107QX3 carboxylase AB431_25555 ENOG4105FUY alpha subunit AB431_25560 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr AB431_25575 ENOG4105CC9 acyl-Coa dehydrogenase AB431_25580 ENOG4105D2B acyl-CoA dehydrogenase AB431_25590 ENOG4108MXC l-carnitine dehydratase bile acid-inducible protein F AB431_25600 ENOG4105CHU acetyl-coa acetyltransferase AB431_25605 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_25610 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB431_25645 ENOG4105D2B acyl-CoA dehydrogenase AB431_25650 ENOG4105CC9 acyl-Coa dehydrogenase AB431_25680 ENOG4105DTD Dehydrogenase AB431_25685 ENOG41061TZ Short-chain dehydrogenase reductase Sdr AB431_25700 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_25705 ENOG4105CGU Enoyl-CoA hydratase AB431_25715 ENOG4108IPT Naphthoate synthase AB431_25720 ENOG4105CC9 acyl-Coa dehydrogenase AB431_25725 ENOG4105CGU Enoyl-CoA hydratase AB431_25730 ENOG4105E39 Enoyl-CoA hydratase AB431_25735 ENOG4105EA8 2-Nitropropane dioxygenase AB431_25745 ENOG4107QSN dihydrolipoamide acetyltransferase AB431_25750 ENOG4105CPP Dehydrogenase, E1 component AB431_25770 ENOG4105CEY Amp-dependent synthetase and ligase AB431_25790 ENOG4105CHR reductase AB431_25800 ENOG4105CEY Amp-dependent synthetase and ligase AB431_25810 ENOG4105C1G acyl-Coa dehydrogenase AB431_25815 ENOG4105FGE Short-chain dehydrogenase reductase Sdr AB431_25830 ENOG4105H9W Short-chain dehydrogenase reductase Sdr AB431_25845 ENOG4105CHR reductase AB431_25900 ENOG4106A3M Cytochrome p-450 AB431_25935 ENOG4105CMR udp-glucose 4-epimerase AB431_25975 ENOG4105EMU Dehydrogenase AB431_25980 ENOG41068W2 Cytochrome p-450 AB431_26020 ENOG4105BZU Histidine kinase AB431_26025 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB431_26125 ENOG4107TB5 TRANSCRIPTIONal AB431_26130 ENOG4106KE4 Dehydrogenase AB431_26205 ENOG4105CHR reductase AB431_26215 ENOG4105X7H acyl-CoA dehydrogenase AB431_26220 ENOG4108KC2 acyl-Coa dehydrogenase AB431_26255 ENOG4105E39 Enoyl-CoA hydratase AB431_26265 ENOG410719E cytochrome p450 AB431_26275 ENOG4105DYW oxidoreductase AB431_26300 ENOG4105X1P Steroid delta-isomerase AB431_26315 ENOG4105CIJ rieske 2fe-2S domain-containing protein AB431_26350 ENOG4105C9U ATP-dependent DNA helicase RecQ AB431_26355 ENOG4105DF3 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity) AB431_26360 ENOG4105DIV Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity) AB431_26370 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein AB431_26400 ENOG410900P UPF0336 protein AB431_26405 ENOG4105X7H acyl-CoA dehydrogenase AB431_26410 ENOG4108RK3 acyl-Coa dehydrogenase AB431_26420 ENOG4105F2C Acetyl-CoA acetyltransferase AB431_26445 ENOG4108R85 Short chain dehydrogenase AB431_26450 ENOG4105E39 Enoyl-CoA hydratase AB431_26465 ENOG4105EA8 2-Nitropropane dioxygenase AB431_26485 ENOG4105F2C Acetyl-CoA acetyltransferase AB431_26490 ENOG4108RZE Tetr family transcriptional regulator AB431_26500 ENOG4105CC9 acyl-Coa dehydrogenase AB431_26505 ENOG4105CEY Amp-dependent synthetase and ligase AB431_26510 ENOG4105CC9 acyl-Coa dehydrogenase AB431_26515 ENOG4105C1G acyl-Coa dehydrogenase AB431_26520 ENOG4105C1G acyl-Coa dehydrogenase AB431_26550 ENOG4105H37 Glyoxalase Bleomycin resistance protein (Dioxygenase AB431_26570 ENOG4105D2B acyl-CoA dehydrogenase AB431_26575 ENOG4108SGK Tetr family transcriptional regulator AB431_26595 ENOG4105DIK (ABC) transporter AB431_26600 ENOG4105CC5 ABC transporter AB431_26620 ENOG4105F8J Adenylate Guanylate cyclase AB431_26625 ENOG4105C2N RNA methyltransferase TrmH family group 3 AB431_26630 ENOG4105C8N cysteinyl-tRNA synthetase AB431_26640 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) AB431_26645 ENOG4108VJ1 Transcriptional regulator (CarD family AB431_26650 ENOG41062GB lipoprotein lpqE AB431_26660 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) AB431_26675 ENOG4105CEN a g-specific adenine glycosylase AB431_26690 ENOG4105EBM Alpha Beta Hydrolase Fold protein AB431_26720 ENOG41082VC UPF0145 protein AB431_26725 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB431_26735 ENOG4105CRK lysyL-tRNA synthetase AB431_26745 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) AB431_26750 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) AB431_26755 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) AB431_26785 ENOG4105EEI dihydropteroate synthase AB431_26790 ENOG4105EUJ GTP cyclohydrolase i AB431_26800 ENOG4105D74 hydrolase AB431_26810 ENOG4105E8R UPF0173 metal-dependent hydrolase AB431_26825 ENOG4105H37 Glyoxalase Bleomycin resistance protein (Dioxygenase AB431_26830 ENOG4105UEI Transcriptional Regulator AraC Family AB431_26835 ENOG4108UGV hypoxanthine phosphoribosyltransferase AB431_26875 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AB431_26880 ENOG4108IG5 Transcriptional regulator AB431_26915 ENOG4108PBI Polysaccharide metabolism AB431_26935 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase AB431_26950 ENOG4107QRG dna polymerase iii AB431_26960 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AB431_26970 ENOG4105VEQ Cold shock protein AB431_26975 ENOG4108I5C dEAD DEAH box helicase AB431_27035 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AB431_27085 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AB431_27110 ENOG4108JQC penicillin-binding protein 1A AB431_27115 ENOG4107RGJ metallophosphoesterase AB431_27160 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AB431_27170 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_27190 ENOG4108WQ6 secreted protein AB431_27195 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AB431_27265 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) AB431_27290 ENOG4105CSH Transporter AB431_27295 ENOG4108KXV response regulator AB431_27310 ENOG4106HB6 Alpha beta hydrolase AB431_27325 ENOG41067HS methyltransferase AB431_27335 ENOG4105E46 N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process AB431_27340 ENOG4105D1K glutamate--cysteine ligase AB431_27350 ENOG4108ZHJ Organic hydroperoxide resistance protein AB431_27355 ENOG4105CH6 catalase AB431_27380 ENOG4108NJC AB431_27390 ENOG4105CFH Aspartokinase AB431_27395 ENOG4105FG0 Nitroreductase AB431_27415 ENOG4105EYU Glutamine amido-transferase AB431_27420 ENOG4105M90 Glutamate synthase alpha subunit domain protein AB431_27425 ENOG4105CBC glutamate synthase AB431_27430 ENOG4105MWK D-amino acid dehydrogenase, small subunit AB431_27460 ENOG4105BZU Histidine kinase AB431_27465 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) AB431_27470 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) AB431_27475 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) AB431_27485 ENOG4105BZU Histidine kinase AB431_27490 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) AB431_27495 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) AB431_27500 ENOG4108RU2 n-acetylmuramoyl-l-alanine amidase AB431_27515 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AB431_27540 ENOG4105XT2 Transcriptional regulator AB431_27580 ENOG4105D9P serine threonine protein kinase AB431_27600 ENOG4105XTG Pfam:DUF156 AB431_27605 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AB431_27610 ENOG4108VCT Sulfite exporter TauE/SafE AB431_27615 ENOG4108UQY Iron-storage protein AB431_27635 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) AB431_27645 ENOG4105DRP amino acid AbC transporter AB431_27650 ENOG4105CDA abc transporter atp-binding protein AB431_27660 ENOG4106A3M Cytochrome p-450 AB431_27665 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) AB431_27670 ENOG4108J2P Alpha beta hydrolase fold AB431_27700 ENOG4108Z6B deaminase AB431_27710 ENOG4105EVN Prephenate dehydrogenase AB431_27720 ENOG4105E90 ABC transporter AB431_27725 ENOG4105E90 ABC transporter AB431_27740 ENOG41060H3 Protein of unknown function (DUF1049) AB431_27745 ENOG4105F8J Adenylate Guanylate cyclase AB431_27760 ENOG4105D2B acyl-CoA dehydrogenase AB431_27795 ENOG4105EUZ Beta-lactamase domain protein AB431_27805 ENOG4105EDW glycosyl transferase, family 39 AB431_27805 ENOG4105EDW glycosyl transferase, family 39 AB431_27815 ENOG4105EDW glycosyl transferase, family 39 AB431_27820 ENOG4105BZU Histidine kinase AB431_27825 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB431_27850 ENOG4105C1G acyl-Coa dehydrogenase AB431_27855 ENOG4105CHR reductase AB431_27885 ENOG4105CIH Imidazole acetol-phosphate transaminase AB431_27900 ENOG4105D7W serine acetyltransferase AB431_27930 ENOG4105CPQ Dehydrogenase AB431_27945 ENOG4108VC7 Protein of unknown function (DUF2587) AB431_27955 ENOG4108MKI Glycosyl transferase, family 2 AB431_27985 ENOG4105IQ5 FAD linked oxidase domain protein AB431_27990 ENOG4108RG3 short-chain dehydrogenase reductase AB431_28005 ENOG4108NUW Cell wall arabinan synthesis protein AB431_28010 ENOG4105J1Z Arabinosyltransferase AB431_28055 ENOG4107QY8 reductase AB431_28060 ENOG4105D8K carboxyl transferase AB431_28100 ENOG4107ISF Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) to the arabinan domain to form terminal beta-(1- 2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids AB431_28105 ENOG4106YN8 Prenyltransferase AB431_28115 ENOG410602S Transferase AB431_28135 ENOG410667J hydrolase AB431_28140 ENOG4105E9Q Acyl-transferase AB431_28145 ENOG4105PSQ Acyl-transferase AB431_28165 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) AB431_28210 ENOG4105CQC Prephenate dehydratase AB431_28225 ENOG4108KGH TRANSCRIPTIONal AB431_28290 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) AB431_28295 ENOG4105CT3 Monooxygenase AB431_28305 ENOG4105BZ4 penicillin-binding protein AB431_28310 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AB431_28315 ENOG4105DCG PHP domain protein AB431_28325 ENOG4105CHH sulfate transporter AB431_28345 ENOG4105CBC glutamate synthase AB431_28350 ENOG4107U53 septum site-determining protein minD AB431_28450 ENOG4105D2B acyl-CoA dehydrogenase AB431_28455 ENOG4105D2B acyl-CoA dehydrogenase AB431_28465 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_28470 ENOG4107S4F acyltransferase, ws dgat mgat AB431_28485 ENOG4105CQ7 ATP-dependent helicase AB431_28515 ENOG4105EXC Acyl-transferase AB431_28520 ENOG4105CHR reductase AB431_28540 ENOG4105CI1 PTS System AB431_28545 ENOG4105C5Y PTS System AB431_28550 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) AB431_28555 ENOG4105CE4 GlcNAc 6-P deacetylase AB431_28625 ENOG4108VEQ Superoxide dismutase AB431_28650 ENOG4105CPQ Dehydrogenase AB431_28655 ENOG4108K8U Glycerol operon regulatory protein AB431_28660 ENOG41062IE glyoxalase bleomycin resistance protein dioxygenase AB431_28670 ENOG4108SGK Tetr family transcriptional regulator AB431_28680 ENOG4105D2B acyl-CoA dehydrogenase AB431_28700 ENOG4105EWI Short-chain dehydrogenase reductase Sdr AB431_28715 ENOG4108WKN secreted protein AB431_28750 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) AB431_28760 ENOG4105CHR reductase AB431_28775 ENOG4105CHR reductase AB431_28790 ENOG410900P UPF0336 protein AB431_28795 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) AB431_28800 ENOG4105BZU Histidine kinase AB431_28805 ENOG4105BZU Histidine kinase AB431_28815 ENOG4105BZU Histidine kinase AB431_28855 ENOG4105D2B acyl-CoA dehydrogenase AB431_29060 ENOG4105K9Q Binds to the 23S rRNA (By similarity) AB431_29065 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) AB431_29070 ENOG4107YH6 single-stranded DNA-binding protein AB431_29075 ENOG410829C Binds together with S18 to 16S ribosomal RNA (By similarity) AB431_29095 ENOG4105BZ4 penicillin-binding protein AB431_29115 ENOG4105CZA synthase AB431_29125 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AB431_29140 ENOG4105DRP amino acid AbC transporter AB431_29145 ENOG4105CDA abc transporter atp-binding protein AB431_29160 ENOG4105EMU Dehydrogenase AB431_29165 ENOG4105C8T Leucyl-tRNA synthetase AB431_29170 ENOG41064CH Probable lipoprotein LpqN AB431_29185 ENOG41082JN Transcriptional regulator AB431_29190 ENOG41081DT UPF0301 protein AB431_29195 ENOG4108M0D major facilitator superfamily AB431_29255 ENOG4105K63 Thioredoxin AB431_29260 ENOG4108E1C hydrolase AB431_29275 ENOG4107QJE Chromosome Partitioning Protein AB431_29280 ENOG4107XUG Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) AB431_29290 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins AB431_29295 ENOG4108CDF RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)