locus-tag	class	description
AB431_00010	COG0592	DNA-directed DNA polymerase activity
AB431_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AB431_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AB431_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AB431_00030	COG0187	DNA topoisomerase II activity
AB431_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AB431_00085	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_00125	COG2815	serine threonine protein kinase
AB431_00125	COG0515	serine threonine protein kinase
AB431_00130	COG0515	serine threonine protein kinase
AB431_00150	COG1716	ATPase activity
AB431_00155	COG1716	ATPase activity
AB431_00175	COG3706	GGDEF domain
AB431_00190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB431_00195	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AB431_00200	COG0531	amino acid
AB431_00235	COG1673	EVE domain
AB431_00250	COG2197	response regulator
AB431_00315	COG4044	May play a role in the intracellular transport of hydrophobic ligands
AB431_00325	COG2226	methyltransferase
AB431_00345	COG1556	Lactate utilization protein
AB431_00350	COG1139	Iron-sulfur cluster binding protein
AB431_00355	COG0247	lactate metabolic process
AB431_00360	COG3158	transport of potassium into the cell
AB431_00395	COG1063	alcohol dehydrogenase
AB431_00400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_00425	COG2124	cytochrome p450
AB431_00435	COG0204	Acyl-transferase
AB431_00445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AB431_00450	COG0243	molybdopterin cofactor binding
AB431_00460	COG1024	Enoyl-CoA hydratase
AB431_00480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_00485	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_00490	COG2267	carboxylic ester hydrolase activity
AB431_00570	COG2124	cytochrome p450
AB431_00580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_00590	COG1845	cytochrome c oxidase, subunit III
AB431_00615	COG1960	acyl-CoA dehydrogenase activity
AB431_00620	COG4221	oxidoreductase activity
AB431_00660	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_00670	COG1960	acyl-CoA dehydrogenase activity
AB431_00675	COG1960	acyl-CoA dehydrogenase activity
AB431_00680	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_00735	COG1960	acyl-CoA dehydrogenase activity
AB431_00740	COG0183	Belongs to the thiolase family
AB431_00750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_00775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_00805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_00835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_00840	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_00865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_00885	COG2304	oxidoreductase activity
AB431_00920	COG3842	ATPase activity
AB431_00935	COG2130	NADP-dependent
AB431_00950	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AB431_00955	COG1074	ATP-dependent DNA helicase activity
AB431_00960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AB431_01015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_01030	COG1960	acyl-CoA dehydrogenase activity
AB431_01040	COG1914	H( )-stimulated, divalent metal cation uptake system
AB431_01090	COG0546	phosphoglycolate phosphatase activity
AB431_01110	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AB431_01140	COG1063	alcohol dehydrogenase
AB431_01145	COG3467	pyridoxamine 5'-phosphate
AB431_01180	COG2072	flavoprotein involved in K transport
AB431_01195	COG0657	acetylesterase activity
AB431_01210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AB431_01220	COG3706	GGDEF domain
AB431_01240	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AB431_01270	COG0783	Belongs to the Dps family
AB431_01275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AB431_01285	COG0730	response to heat
AB431_01305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB431_01305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB431_01305	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AB431_01310	COG1105	Belongs to the carbohydrate kinase PfkB family
AB431_01315	COG1349	DNA-binding transcription factor activity
AB431_01320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AB431_01340	COG1012	belongs to the aldehyde dehydrogenase family
AB431_01350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AB431_01355	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_01365	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AB431_01370	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AB431_01380	COG2365	Tyrosine phosphatase family
AB431_01385	COG1960	acyl-CoA dehydrogenase activity
AB431_01395	COG4585	Histidine kinase
AB431_01410	COG1309	transcriptional regulator
AB431_01430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB431_01460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_01490	COG3619	membrane
AB431_01495	COG0300	oxidoreductase activity
AB431_01540	COG0039	L-malate dehydrogenase activity
AB431_01555	COG2267	carboxylic ester hydrolase activity
AB431_01580	COG0243	molybdopterin cofactor binding
AB431_01585	COG1414	Transcriptional regulator
AB431_01605	COG0129	dihydroxy-acid dehydratase activity
AB431_01615	COG1937	Protein conserved in bacteria
AB431_01625	COG1376	ErfK ybiS ycfS ynhG family protein
AB431_01635	COG2814	Major facilitator Superfamily
AB431_01640	COG0640	Transcriptional regulator
AB431_01650	COG3590	peptidase
AB431_01665	COG1832	CoA-binding protein
AB431_01675	COG2409	Drug exporters of the RND superfamily
AB431_01695	COG2205	protein histidine kinase activity
AB431_01725	COG2409	Drug exporters of the RND superfamily
AB431_01735	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AB431_01750	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AB431_01760	COG1024	Enoyl-CoA hydratase
AB431_01765	COG2188	Transcriptional regulator
AB431_01770	COG1960	acyl-CoA dehydrogenase activity
AB431_01790	COG1960	acyl-CoA dehydrogenase activity
AB431_01795	COG1960	acyl-CoA dehydrogenase activity
AB431_01810	COG1063	alcohol dehydrogenase
AB431_01840	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_01860	COG1960	acyl-CoA dehydrogenase activity
AB431_01865	COG1960	acyl-CoA dehydrogenase activity
AB431_01880	COG1309	transcriptional regulator
AB431_01885	COG1960	acyl-CoA dehydrogenase activity
AB431_01900	COG0500	methyltransferase
AB431_01905	COG0297	glycogen (starch) synthase activity
AB431_01955	COG4981	capsule polysaccharide biosynthetic process
AB431_01985	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_01990	COG0183	Belongs to the thiolase family
AB431_02000	COG1960	acyl-CoA dehydrogenase activity
AB431_02020	COG5651	PPE family
AB431_02035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB431_02045	COG1053	succinate dehydrogenase
AB431_02060	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AB431_02075	COG1846	Transcriptional regulator
AB431_02085	COG1984	allophanate hydrolase subunit 2
AB431_02090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AB431_02150	COG3104	oligopeptide transport
AB431_02155	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_02160	COG1960	acyl-CoA dehydrogenase activity
AB431_02165	COG1960	acyl-CoA dehydrogenase activity
AB431_02170	COG1024	Enoyl-CoA hydratase
AB431_02180	COG0543	2 iron, 2 sulfur cluster binding
AB431_02180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AB431_02190	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AB431_02190	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AB431_02195	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_02200	COG1309	transcriptional regulator
AB431_02220	COG1349	DNA-binding transcription factor activity
AB431_02225	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB431_02225	COG2213	PTS system mannitol-specific
AB431_02230	COG1063	alcohol dehydrogenase
AB431_02245	COG1012	belongs to the aldehyde dehydrogenase family
AB431_02250	COG1960	acyl-CoA dehydrogenase activity
AB431_02255	COG1012	belongs to the aldehyde dehydrogenase family
AB431_02275	COG3119	arylsulfatase activity
AB431_02285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AB431_02295	COG1169	isochorismate synthase
AB431_02300	COG1021	2,3-dihydroxybenzoate-AMP ligase
AB431_02305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB431_02310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB431_02375	COG1404	Belongs to the peptidase S8 family
AB431_02395	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_02400	COG1960	acyl-CoA dehydrogenase activity
AB431_02410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AB431_02420	COG0346	lactoylglutathione lyase activity
AB431_02450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AB431_02465	COG4424	Sulfotransferase
AB431_02520	COG0655	NAD(P)H dehydrogenase (quinone) activity
AB431_02555	COG0028	Belongs to the TPP enzyme family
AB431_02625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AB431_02650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB431_02670	COG0247	lactate metabolic process
AB431_02670	COG2181	nitrate reductase activity
AB431_02720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_02790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AB431_02795	COG0484	heat shock protein binding
AB431_02800	COG0789	Transcriptional regulator
AB431_02840	COG0542	response to heat
AB431_02885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB431_02895	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AB431_02895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AB431_02900	COG2226	methyltransferase
AB431_02915	COG2890	protein-(glutamine-N5) methyltransferase activity
AB431_02960	COG0586	Pfam SNARE associated Golgi protein
AB431_02985	COG1289	transmembrane transporter activity
AB431_02995	COG1994	Peptidase M50
AB431_03005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AB431_03020	COG2124	cytochrome p450
AB431_03025	COG2409	Drug exporters of the RND superfamily
AB431_03040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AB431_03045	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AB431_03090	COG4221	oxidoreductase activity
AB431_03105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_03115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AB431_03120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_03155	COG0640	Transcriptional regulator
AB431_03165	COG0515	serine threonine protein kinase
AB431_03170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB431_03185	COG2801	Transposase and inactivated derivatives
AB431_03185	COG3415	Transposase
AB431_03195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB431_03195	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AB431_03205	COG2022	thiamine diphosphate biosynthetic process
AB431_03220	COG0701	Predicted permease
AB431_03225	COG2234	aminopeptidase activity
AB431_03235	COG2233	PERMEase
AB431_03265	COG0351	phosphomethylpyrimidine kinase
AB431_03300	COG2130	NADP-dependent
AB431_03310	COG2124	cytochrome p450
AB431_03325	COG0242	peptide deformylase activity
AB431_03355	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AB431_03390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AB431_03390	COG2111	Na H antiporter
AB431_03420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AB431_03440	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_03450	COG3832	glyoxalase III activity
AB431_03455	COG3848	Pyruvate phosphate dikinase
AB431_03455	COG0574	Belongs to the PEP-utilizing enzyme family
AB431_03475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB431_03495	COG1819	glycosyl
AB431_03515	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_03520	COG1309	transcriptional regulator
AB431_03530	COG0459	protein refolding
AB431_03555	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AB431_03580	COG2326	polyphosphate kinase activity
AB431_03610	COG1505	serine-type exopeptidase activity
AB431_03670	COG2326	polyphosphate kinase activity
AB431_03690	COG2733	membrane
AB431_03715	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AB431_03745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AB431_03770	COG0438	transferase activity, transferring glycosyl groups
AB431_03785	COG5002	protein histidine kinase activity
AB431_03790	COG0745	RESPONSE REGULATOR receiver
AB431_03885	COG2030	dehydratase
AB431_03890	COG0560	Phosphoserine phosphatase
AB431_03955	COG2826	transposase and inactivated derivatives, IS30 family
AB431_03975	COG0723	plastoquinol--plastocyanin reductase activity
AB431_03985	COG3794	PFAM blue (type 1) copper domain protein
AB431_04015	COG0406	alpha-ribazole phosphatase activity
AB431_04025	COG0785	Cytochrome C biogenesis protein
AB431_04035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AB431_04070	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AB431_04080	COG0450	alkyl hydroperoxide reductase
AB431_04085	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB431_04090	COG2070	2-Nitropropane dioxygenase
AB431_04100	COG2205	protein histidine kinase activity
AB431_04105	COG0745	RESPONSE REGULATOR receiver
AB431_04140	COG0640	Transcriptional regulator
AB431_04185	COG0346	lactoylglutathione lyase activity
AB431_04190	COG4221	oxidoreductase activity
AB431_04225	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_04240	COG4948	Mandelate Racemase Muconate Lactonizing
AB431_04255	COG1309	transcriptional regulator
AB431_04280	COG4977	sequence-specific DNA binding
AB431_04295	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AB431_04310	COG0438	transferase activity, transferring glycosyl groups
AB431_04315	COG0300	oxidoreductase activity
AB431_04320	COG2226	methyltransferase
AB431_04330	COG0644	oxidoreductase
AB431_04340	COG0501	Belongs to the peptidase M48B family
AB431_04345	COG0668	transmembrane transport
AB431_04365	COG2072	flavoprotein involved in K transport
AB431_04370	COG1666	GTP binding
AB431_04420	COG0596	Alpha beta hydrolase
AB431_04445	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AB431_04525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AB431_04530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AB431_04540	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AB431_04560	COG0156	8-amino-7-oxononanoate synthase activity
AB431_04565	COG0287	Prephenate dehydrogenase
AB431_04570	COG0723	plastoquinol--plastocyanin reductase activity
AB431_04580	COG0596	Alpha beta hydrolase
AB431_04590	COG0512	Glutamine amidotransferase of anthranilate synthase
AB431_04590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AB431_04595	COG1605	Chorismate mutase
AB431_04625	COG2208	phosphoserine phosphatase activity
AB431_04625	COG2770	Histidine kinase
AB431_04630	COG0596	Alpha beta hydrolase
AB431_04665	COG0477	Major facilitator Superfamily
AB431_04695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AB431_04700	COG0514	ATP-dependent DNA helicase (RecQ)
AB431_04710	COG1201	RNA secondary structure unwinding
AB431_04800	COG1309	transcriptional regulator
AB431_04850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB431_04880	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_04935	COG1305	Transglutaminase-like
AB431_04965	COG1278	Cold shock
AB431_04970	COG0513	Belongs to the DEAD box helicase family
AB431_04980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB431_04985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB431_04990	COG2813	Specifically methylates the guanine in position
AB431_05040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AB431_05050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB431_05065	COG2188	Transcriptional regulator
AB431_05080	COG2267	carboxylic ester hydrolase activity
AB431_05095	COG1024	Enoyl-CoA hydratase
AB431_05105	COG0739	heme binding
AB431_05110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB431_05125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AB431_05130	COG2030	dehydratase
AB431_05135	COG2030	dehydratase
AB431_05150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AB431_05165	COG0081	regulation of translation
AB431_05170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AB431_05205	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AB431_05230	COG0673	inositol 2-dehydrogenase activity
AB431_05250	COG0438	transferase activity, transferring glycosyl groups
AB431_05255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB431_05260	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AB431_05285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB431_05290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB431_05295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB431_05310	COG2318	DinB family
AB431_05345	COG1940	carbohydrate kinase activity
AB431_05355	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AB431_05360	COG0222	ribosome binding
AB431_05395	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AB431_05405	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AB431_05420	COG1960	acyl-CoA dehydrogenase activity
AB431_05430	COG3327	negative regulation of DNA-templated transcription, initiation
AB431_05435	COG1024	Enoyl-CoA hydratase
AB431_05445	COG2197	response regulator
AB431_05480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AB431_05500	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_05505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AB431_05510	COG1834	amidinotransferase
AB431_05515	COG1522	sequence-specific DNA binding
AB431_05545	COG0535	radical SAM domain protein
AB431_05575	COG0477	Major facilitator Superfamily
AB431_05590	COG2272	Belongs to the type-B carboxylesterase lipase family
AB431_05605	COG0346	lactoylglutathione lyase activity
AB431_05635	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AB431_05640	COG0088	Forms part of the polypeptide exit tunnel
AB431_05650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AB431_05660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AB431_05665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AB431_05675	COG0255	Belongs to the universal ribosomal protein uL29 family
AB431_05680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AB431_05700	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AB431_05710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AB431_05715	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AB431_05725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AB431_05730	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AB431_05740	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AB431_05745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AB431_05750	COG1841	ribosomal large subunit assembly
AB431_05765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_05770	COG0616	signal peptide processing
AB431_05780	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AB431_05785	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AB431_05790	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AB431_05800	COG0563	adenylate kinase activity
AB431_05830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB431_05835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AB431_05850	COG1960	acyl-CoA dehydrogenase activity
AB431_05860	COG4565	transcriptional regulatory protein
AB431_05865	COG3290	protein histidine kinase activity
AB431_05870	COG1301	dicarboxylic acid transport
AB431_05905	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_05915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB431_05975	COG1376	ErfK ybiS ycfS ynhG family protein
AB431_05995	COG2032	superoxide dismutase activity
AB431_06000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AB431_06015	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_06030	COG1335	isochorismatase
AB431_06045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AB431_06045	COG1017	nitric oxide dioxygenase activity
AB431_06050	COG0523	cobalamin synthesis protein
AB431_06055	COG3250	beta-galactosidase activity
AB431_06085	COG1764	response to oxidative stress
AB431_06090	COG1846	Transcriptional regulator
AB431_06095	COG1126	abc transporter atp-binding protein
AB431_06100	COG0765	amino acid transport
AB431_06150	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_06155	COG0183	Belongs to the thiolase family
AB431_06220	COG1024	Enoyl-CoA hydratase
AB431_06235	COG0183	Belongs to the thiolase family
AB431_06245	COG0657	acetylesterase activity
AB431_06255	COG1714	RDD family
AB431_06285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AB431_06295	COG1331	Highly conserved protein containing a thioredoxin domain
AB431_06300	COG3631	Ketosteroid isomerase-related protein
AB431_06335	COG0572	uridine kinase
AB431_06345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AB431_06355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AB431_06360	COG0726	polysaccharide deacetylase
AB431_06370	COG1295	ribonuclease BN
AB431_06440	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AB431_06450	COG3119	arylsulfatase activity
AB431_06470	COG1570	exodeoxyribonuclease VII activity
AB431_06490	COG0012	GTP binding
AB431_06560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AB431_06590	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_06615	COG1024	Enoyl-CoA hydratase
AB431_06630	COG0702	epimerase
AB431_06645	COG1024	Enoyl-CoA hydratase
AB431_06650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_06675	COG2188	Transcriptional regulator
AB431_06690	COG3467	pyridoxamine 5'-phosphate
AB431_06700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB431_06755	COG2124	cytochrome p450
AB431_06770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_06780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AB431_06785	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AB431_06810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_06820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AB431_06835	COG0076	glutamate decarboxylase activity
AB431_06865	COG2188	Transcriptional regulator
AB431_06890	COG0456	acetyltransferase
AB431_06895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AB431_06905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AB431_07020	COG0516	GMP reductase activity
AB431_07055	COG0519	Catalyzes the synthesis of GMP from XMP
AB431_07055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AB431_07060	COG3588	fructose-bisphosphate aldolase
AB431_07085	COG4221	oxidoreductase activity
AB431_07095	COG0406	alpha-ribazole phosphatase activity
AB431_07120	COG3973	AAA domain
AB431_07125	COG0587	DNA-directed DNA polymerase activity
AB431_07130	COG1403	HNH endonuclease
AB431_07145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AB431_07155	COG2205	protein histidine kinase activity
AB431_07160	COG2018	Roadblock/LC7 domain
AB431_07175	COG1357	PFAM Pentapeptide repeats (8 copies)
AB431_07215	COG0842	Transport permease protein
AB431_07215	COG1131	(ABC) transporter
AB431_07215	COG1716	ATPase activity
AB431_07220	COG1902	pentaerythritol trinitrate reductase activity
AB431_07220	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB431_07255	COG2873	o-acetylhomoserine
AB431_07310	COG1295	ribonuclease BN
AB431_07315	COG1686	Belongs to the peptidase S11 family
AB431_07325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AB431_07340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB431_07345	COG1960	acyl-CoA dehydrogenase activity
AB431_07355	COG2030	dehydratase
AB431_07395	COG2009	succinate dehydrogenase
AB431_07410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AB431_07435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB431_07445	COG3180	Ammonia monooxygenase
AB431_07460	COG1473	amidohydrolase
AB431_07460	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AB431_07485	COG0564	pseudouridine synthase activity
AB431_07515	COG1116	anion transmembrane transporter activity
AB431_07520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB431_07525	COG1116	anion transmembrane transporter activity
AB431_07535	COG1201	RNA secondary structure unwinding
AB431_07565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB431_07575	COG0596	Alpha beta hydrolase
AB431_07580	COG1309	transcriptional regulator
AB431_07590	COG1012	belongs to the aldehyde dehydrogenase family
AB431_07600	COG1522	sequence-specific DNA binding
AB431_07630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB431_07630	COG0723	plastoquinol--plastocyanin reductase activity
AB431_07680	COG4770	biotin carboxylase activity
AB431_07710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AB431_07720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AB431_07730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB431_07750	COG1215	transferase activity, transferring glycosyl groups
AB431_07755	COG1216	Glycosyl transferase, family 2
AB431_07810	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AB431_07830	COG1316	TRANSCRIPTIONal
AB431_07845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AB431_07880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB431_07900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB431_07905	COG0531	amino acid
AB431_07910	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB431_07930	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AB431_07945	COG0745	RESPONSE REGULATOR receiver
AB431_07970	COG0596	Alpha beta hydrolase
AB431_07980	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AB431_08000	COG2326	polyphosphate kinase activity
AB431_08030	COG0656	L-ascorbic acid biosynthetic process
AB431_08035	COG1162	GTPase activity
AB431_08040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AB431_08045	COG2135	peptidase activity
AB431_08075	COG4638	Rieske (2fe-2S)
AB431_08100	COG1309	transcriptional regulator
AB431_08105	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_08110	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_08135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_08175	COG2124	cytochrome p450
AB431_08190	COG2124	cytochrome p450
AB431_08200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AB431_08205	COG1595	DNA-templated transcription, initiation
AB431_08210	COG5662	AntiSigma factor
AB431_08215	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AB431_08255	COG0406	alpha-ribazole phosphatase activity
AB431_08270	COG0513	Belongs to the DEAD box helicase family
AB431_08315	COG0596	Alpha beta hydrolase
AB431_08335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB431_08370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AB431_08385	COG3480	Lon protease (S16) C-terminal proteolytic domain
AB431_08395	COG1234	tRNA 3'-trailer cleavage
AB431_08425	COG0693	protein deglycase activity
AB431_08425	COG0753	catalase activity
AB431_08470	COG2031	fatty acid transporter
AB431_08490	COG2814	Major facilitator Superfamily
AB431_08570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB431_08575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AB431_08580	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_08585	COG2409	Drug exporters of the RND superfamily
AB431_08595	COG2226	methyltransferase
AB431_08600	COG2124	cytochrome p450
AB431_08605	COG0789	Transcriptional regulator
AB431_08640	COG0778	Nitroreductase
AB431_08675	COG0300	oxidoreductase activity
AB431_08685	COG1024	Enoyl-CoA hydratase
AB431_08705	COG0713	ATP synthesis coupled electron transport
AB431_08715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB431_08720	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AB431_08725	COG1034	ATP synthesis coupled electron transport
AB431_08745	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB431_08750	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB431_08785	COG1960	acyl-CoA dehydrogenase activity
AB431_08795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB431_08805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AB431_08810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_08825	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AB431_08830	COG0604	alcohol dehydrogenase
AB431_08845	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_08855	COG1012	belongs to the aldehyde dehydrogenase family
AB431_08860	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_08875	COG2124	cytochrome p450
AB431_08885	COG0243	molybdopterin cofactor binding
AB431_08895	COG0667	Aldo Keto reductase
AB431_08900	COG1960	acyl-CoA dehydrogenase activity
AB431_08915	COG0483	inositol monophosphate 1-phosphatase activity
AB431_08950	COG0668	transmembrane transport
AB431_08960	COG2884	Cell division ATP-binding protein ftsE
AB431_08965	COG2177	Part of the ABC transporter FtsEX involved in
AB431_08970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AB431_08980	COG5651	PPE family
AB431_09030	COG1032	radical SAM domain protein
AB431_09055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_09085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB431_09090	COG0784	Response regulator, receiver
AB431_09095	COG4251	negative regulation of phosphorylation
AB431_09145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AB431_09155	COG2814	Major facilitator Superfamily
AB431_09185	COG0582	viral genome integration into host DNA
AB431_09200	COG1674	ftsk spoiiie
AB431_09200	COG1280	lysine exporter protein (LysE YggA)
AB431_09320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_09345	COG4191	Histidine kinase
AB431_09350	COG2197	response regulator
AB431_09385	COG2132	Multicopper oxidase
AB431_09405	COG0640	Transcriptional regulator
AB431_09430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AB431_09440	COG0235	Class ii aldolase
AB431_09445	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_09455	COG0604	alcohol dehydrogenase
AB431_09460	COG0492	ferredoxin-NADP+ reductase activity
AB431_09480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB431_09510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_09535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_09545	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_09555	COG4638	Rieske (2fe-2S)
AB431_09605	COG2072	flavoprotein involved in K transport
AB431_09610	COG0596	Alpha beta hydrolase
AB431_09620	COG2267	carboxylic ester hydrolase activity
AB431_09650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB431_09655	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AB431_09660	COG0477	Major facilitator Superfamily
AB431_09690	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_09700	COG1960	acyl-CoA dehydrogenase activity
AB431_09705	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AB431_09715	COG1966	Carbon starvation protein
AB431_09735	COG1960	acyl-CoA dehydrogenase activity
AB431_09745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB431_09760	COG0298	carbon dioxide binding
AB431_09790	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AB431_09805	COG0375	protein maturation
AB431_09815	COG0298	carbon dioxide binding
AB431_09820	COG0409	Hydrogenase expression formation protein
AB431_09865	COG0431	NADPH-dependent FMN reductase
AB431_09880	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_09895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB431_09925	COG3384	dioxygenase
AB431_09935	COG3415	Transposase
AB431_09935	COG2801	Transposase and inactivated derivatives
AB431_09950	COG1309	transcriptional regulator
AB431_10005	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_10010	COG0028	Belongs to the TPP enzyme family
AB431_10025	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AB431_10050	COG1064	alcohol dehydrogenase
AB431_10075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB431_10080	COG2364	Membrane
AB431_10085	COG1119	ATPase activity
AB431_10115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB431_10120	COG0110	maltose O-acetyltransferase activity
AB431_10130	COG0640	Transcriptional regulator
AB431_10150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AB431_10160	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AB431_10180	COG0482	sulfurtransferase activity
AB431_10200	COG1752	Esterase of the alpha-beta hydrolase superfamily
AB431_10240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB431_10260	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AB431_10265	COG0154	amidase activity
AB431_10285	COG2376	Dihydroxyacetone kinase
AB431_10335	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_10345	COG0714	Associated with various cellular activities
AB431_10360	COG0300	oxidoreductase activity
AB431_10365	COG2124	cytochrome p450
AB431_10370	COG1309	transcriptional regulator
AB431_10395	COG0440	acetolactate synthase activity
AB431_10420	COG0473	3-isopropylmalate dehydrogenase activity
AB431_10425	COG2271	Major facilitator Superfamily
AB431_10430	COG0179	Fumarylacetoacetate (FAA) hydrolase
AB431_10435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB431_10460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AB431_10480	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AB431_10495	COG0626	cystathionine gamma-synthase activity
AB431_10545	COG1461	Dihydroxyacetone kinase
AB431_10550	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AB431_10560	COG1959	2 iron, 2 sulfur cluster binding
AB431_10565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AB431_10565	COG1017	nitric oxide dioxygenase activity
AB431_10570	COG0656	L-ascorbic acid biosynthetic process
AB431_10590	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AB431_10595	COG0742	ribosomal rna small subunit methyltransferase
AB431_10600	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AB431_10620	COG0571	ribonuclease III activity
AB431_10625	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AB431_10635	COG1254	Belongs to the acylphosphatase family
AB431_10650	COG2208	phosphoserine phosphatase activity
AB431_10660	COG1304	FMN binding
AB431_10680	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AB431_10710	COG1686	Belongs to the peptidase S11 family
AB431_10720	COG1686	Belongs to the peptidase S11 family
AB431_10770	COG0335	large ribosomal subunit rRNA binding
AB431_10780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AB431_10795	COG2814	Major facilitator Superfamily
AB431_10820	COG0606	chelatase, subunit chli
AB431_10845	COG1937	Protein conserved in bacteria
AB431_10850	COG4974	Belongs to the 'phage' integrase family
AB431_10855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AB431_10870	COG0052	Belongs to the universal ribosomal protein uS2 family
AB431_10880	COG0154	amidase activity
AB431_10895	COG1136	(ABC) transporter
AB431_10925	COG0528	UMP kinase activity
AB431_10940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AB431_10950	COG0415	Belongs to the DNA photolyase family
AB431_10955	COG0531	amino acid
AB431_10970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AB431_10975	COG0750	zinc metalloprotease
AB431_11055	COG0367	asparagine synthase
AB431_11070	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AB431_11080	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_11085	COG2186	Transcriptional regulator
AB431_11095	COG1063	alcohol dehydrogenase
AB431_11120	COG2860	membrane
AB431_11125	COG1473	amidohydrolase
AB431_11160	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_11165	COG4638	Rieske (2fe-2S)
AB431_11210	COG0310	cobalt ion transport
AB431_11225	COG1122	ATPase activity
AB431_11240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AB431_11255	COG0579	oxidoreductase
AB431_11280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AB431_11280	COG1648	precorrin-2 dehydrogenase activity
AB431_11325	COG0779	Required for maturation of 30S ribosomal subunits
AB431_11345	COG0481	GTPase activity
AB431_11355	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AB431_11375	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AB431_11445	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AB431_11450	COG1185	polyribonucleotide nucleotidyltransferase activity
AB431_11455	COG0612	Peptidase, M16
AB431_11475	COG0686	Belongs to the AlaDH PNT family
AB431_11480	COG1522	sequence-specific DNA binding
AB431_11485	COG1403	HNH endonuclease
AB431_11535	COG0142	geranyltranstransferase activity
AB431_11585	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AB431_11590	COG3214	Protein conserved in bacteria
AB431_11595	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_11600	COG3706	GGDEF domain
AB431_11610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB431_11615	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AB431_11630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AB431_11655	COG2826	transposase and inactivated derivatives, IS30 family
AB431_11660	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AB431_11670	COG1546	Belongs to the CinA family
AB431_11670	COG1058	Belongs to the CinA family
AB431_11675	COG1396	sequence-specific DNA binding
AB431_11690	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
AB431_11705	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AB431_11715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_11735	COG0765	amino acid transport
AB431_11740	COG0765	amino acid transport
AB431_11745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB431_11750	COG1126	abc transporter atp-binding protein
AB431_11755	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AB431_11765	COG1196	nuclear chromosome segregation
AB431_11770	COG0697	spore germination
AB431_11780	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AB431_11785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AB431_11790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AB431_11805	COG1960	acyl-CoA dehydrogenase activity
AB431_11815	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AB431_11825	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AB431_11900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AB431_11915	COG0483	inositol monophosphate 1-phosphatase activity
AB431_11935	COG0756	dUTP diphosphatase activity
AB431_11960	COG0477	Major facilitator Superfamily
AB431_11970	COG0569	domain protein
AB431_11975	COG0531	amino acid
AB431_11980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AB431_12000	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AB431_12010	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AB431_12040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AB431_12090	COG0745	RESPONSE REGULATOR receiver
AB431_12120	COG5002	protein histidine kinase activity
AB431_12125	COG0745	RESPONSE REGULATOR receiver
AB431_12200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AB431_12205	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB431_12210	COG0022	dehydrogenase e1 component
AB431_12210	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB431_12215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AB431_12220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB431_12265	COG1022	Amp-dependent synthetase and ligase
AB431_12275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AB431_12310	COG4974	Belongs to the 'phage' integrase family
AB431_12495	COG4762	Protein conserved in bacteria
AB431_12525	COG1560	Kdo2-lipid A biosynthetic process
AB431_12530	COG0438	transferase activity, transferring glycosyl groups
AB431_12540	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AB431_12545	COG1946	Acyl-CoA thioesterase
AB431_12550	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AB431_12575	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB431_12590	COG1309	transcriptional regulator
AB431_12595	COG0477	Major facilitator Superfamily
AB431_12600	COG0217	transcriptional regulatory protein
AB431_12605	COG0243	molybdopterin cofactor binding
AB431_12625	COG2255	four-way junction helicase activity
AB431_12645	COG3002	Belongs to the UPF0753 family
AB431_12660	COG0745	RESPONSE REGULATOR receiver
AB431_12660	COG3706	GGDEF domain
AB431_12665	COG3320	Male sterility
AB431_12665	COG1022	Amp-dependent synthetase and ligase
AB431_12685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AB431_12705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB431_12710	COG0747	negative chemotaxis
AB431_12715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AB431_12720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB431_12740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AB431_12755	COG0124	histidyl-tRNA synthetase
AB431_12780	COG0753	catalase activity
AB431_12790	COG0411	ABC transporter
AB431_12805	COG0683	leucine binding
AB431_12835	COG2272	Belongs to the type-B carboxylesterase lipase family
AB431_12845	COG1960	acyl-CoA dehydrogenase activity
AB431_12880	COG2272	Belongs to the type-B carboxylesterase lipase family
AB431_12890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AB431_12910	COG0183	Belongs to the thiolase family
AB431_12915	COG1733	regulation of RNA biosynthetic process
AB431_12980	COG1960	acyl-CoA dehydrogenase activity
AB431_12995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_13015	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_13025	COG0697	spore germination
AB431_13050	COG0432	Pfam Uncharacterised protein family UPF0047
AB431_13055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AB431_13060	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AB431_13070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AB431_13105	COG0714	Associated with various cellular activities
AB431_13110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AB431_13120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AB431_13130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AB431_13145	COG0006	proline dipeptidase activity
AB431_13150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AB431_13155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB431_13170	COG1960	acyl-CoA dehydrogenase activity
AB431_13180	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AB431_13185	COG0540	Belongs to the ATCase OTCase family
AB431_13200	COG0505	Belongs to the CarA family
AB431_13210	COG0284	orotidine-5'-phosphate decarboxylase activity
AB431_13245	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_13250	COG2972	Histidine kinase
AB431_13250	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AB431_13280	COG1704	LemA family
AB431_13285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AB431_13315	COG0693	protein deglycase activity
AB431_13320	COG0477	Major facilitator Superfamily
AB431_13350	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AB431_13350	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AB431_13370	COG0322	excinuclease ABC activity
AB431_13385	COG1481	regulation of sporulation
AB431_13395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB431_13400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AB431_13405	COG0126	phosphoglycerate kinase activity
AB431_13410	COG0149	triose-phosphate isomerase activity
AB431_13425	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AB431_13455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AB431_13465	COG0109	protoheme IX farnesyltransferase activity
AB431_13485	COG0069	glutamate synthase activity
AB431_13520	COG0396	ATPase activity
AB431_13525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AB431_13535	COG2151	metal-sulfur cluster biosynthetic enzyme
AB431_13555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB431_13565	COG0488	(ABC) transporter
AB431_13575	COG1309	transcriptional regulator
AB431_13580	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AB431_13590	COG3883	PFAM NLP P60 protein
AB431_13590	COG0791	NLP P60 protein
AB431_13600	COG0714	Associated with various cellular activities
AB431_13620	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AB431_13670	COG3321	synthase
AB431_13670	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_13670	COG0604	alcohol dehydrogenase
AB431_13715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AB431_13735	COG0252	asparaginase activity
AB431_13760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB431_13810	COG0477	Major facilitator Superfamily
AB431_13820	COG0243	molybdopterin cofactor binding
AB431_13825	COG2223	nitrite transmembrane transporter activity
AB431_13830	COG2146	nitrite reductase [NAD(P)H] activity
AB431_13830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB431_13895	COG0156	8-amino-7-oxononanoate synthase activity
AB431_13970	COG1280	lysine exporter protein (LysE YggA)
AB431_13985	COG0131	Imidazoleglycerol-phosphate dehydratase
AB431_13990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AB431_14000	COG0483	inositol monophosphate 1-phosphatase activity
AB431_14010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AB431_14015	COG1119	ATPase activity
AB431_14025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AB431_14035	COG0134	indole-3-glycerol-phosphate synthase activity
AB431_14055	COG1403	HNH endonuclease
AB431_14110	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AB431_14125	COG2124	cytochrome p450
AB431_14140	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_14150	COG4221	oxidoreductase activity
AB431_14165	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_14195	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_14205	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AB431_14220	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_14235	COG2124	cytochrome p450
AB431_14250	COG1309	transcriptional regulator
AB431_14265	COG1960	acyl-CoA dehydrogenase activity
AB431_14280	COG1960	acyl-CoA dehydrogenase activity
AB431_14295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_14320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_14360	COG1960	acyl-CoA dehydrogenase activity
AB431_14370	COG1960	acyl-CoA dehydrogenase activity
AB431_14375	COG1960	acyl-CoA dehydrogenase activity
AB431_14385	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_14405	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_14420	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_14425	COG1024	Enoyl-CoA hydratase
AB431_14435	COG1960	acyl-CoA dehydrogenase activity
AB431_14440	COG1024	Enoyl-CoA hydratase
AB431_14450	COG1024	Enoyl-CoA hydratase
AB431_14455	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_14495	COG1024	Enoyl-CoA hydratase
AB431_14505	COG1960	acyl-CoA dehydrogenase activity
AB431_14520	COG1024	Enoyl-CoA hydratase
AB431_14540	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_14560	COG0714	Associated with various cellular activities
AB431_14625	COG4122	O-methyltransferase activity
AB431_14635	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AB431_14640	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AB431_14645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AB431_14670	COG2378	regulation of single-species biofilm formation
AB431_14715	COG0300	oxidoreductase activity
AB431_14770	COG0714	Associated with various cellular activities
AB431_14820	COG0463	Glycosyl transferase, family 2
AB431_14835	COG0514	ATP-dependent DNA helicase (RecQ)
AB431_14840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_14855	COG2272	Belongs to the type-B carboxylesterase lipase family
AB431_14895	COG3265	gluconokinase activity
AB431_14940	COG0438	transferase activity, transferring glycosyl groups
AB431_14950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AB431_14955	COG1335	isochorismatase
AB431_14970	COG2020	methyltransferase activity
AB431_14975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AB431_14990	COG1177	transmembrane transport
AB431_14995	COG1176	ABC-type spermidine putrescine transport system, permease component I
AB431_15010	COG1960	acyl-CoA dehydrogenase activity
AB431_15025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB431_15055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_15135	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_15140	COG1960	acyl-CoA dehydrogenase activity
AB431_15145	COG2072	flavoprotein involved in K transport
AB431_15150	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_15190	COG2072	flavoprotein involved in K transport
AB431_15205	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_15210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_15220	COG1024	Enoyl-CoA hydratase
AB431_15235	COG0346	lactoylglutathione lyase activity
AB431_15245	COG2072	flavoprotein involved in K transport
AB431_15255	COG5002	protein histidine kinase activity
AB431_15260	COG0668	transmembrane transport
AB431_15265	COG0579	oxidoreductase
AB431_15285	COG5006	permease, DMT superfamily
AB431_15290	COG2814	Major facilitator Superfamily
AB431_15315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB431_15400	COG1278	Cold shock
AB431_15420	COG2267	carboxylic ester hydrolase activity
AB431_15430	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AB431_15495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_15500	COG1063	alcohol dehydrogenase
AB431_15515	COG1846	Transcriptional regulator
AB431_15530	COG0596	Alpha beta hydrolase
AB431_15550	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_15585	COG3485	protocatechuate 3,4-dioxygenase
AB431_15620	COG1063	alcohol dehydrogenase
AB431_15630	COG4638	Rieske (2fe-2S)
AB431_15695	COG4638	Rieske (2fe-2S)
AB431_15700	COG1414	Transcriptional regulator
AB431_15715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AB431_15725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB431_15735	COG3485	protocatechuate 3,4-dioxygenase
AB431_15740	COG3485	protocatechuate 3,4-dioxygenase
AB431_15745	COG1414	Transcriptional regulator
AB431_15750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB431_15775	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AB431_15780	COG4638	Rieske (2fe-2S)
AB431_15785	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_15825	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AB431_15830	COG4681	YaeQ
AB431_15865	COG1278	Cold shock
AB431_15890	COG3757	hydrolase, family 25
AB431_15905	COG3011	Protein conserved in bacteria
AB431_15920	COG5001	Diguanylate cyclase
AB431_15925	COG1252	NADH dehydrogenase
AB431_15955	COG2409	Drug exporters of the RND superfamily
AB431_16005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB431_16010	COG0545	Peptidyl-prolyl cis-trans isomerase
AB431_16055	COG1755	Isoprenylcysteine carboxyl methyltransferase
AB431_16110	COG0657	acetylesterase activity
AB431_16115	COG3883	PFAM NLP P60 protein
AB431_16115	COG0791	NLP P60 protein
AB431_16160	COG0058	SHG alpha-glucan phosphorylase activity
AB431_16165	COG1063	alcohol dehydrogenase
AB431_16190	COG4948	Mandelate Racemase Muconate Lactonizing
AB431_16210	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AB431_16250	COG0667	Aldo Keto reductase
AB431_16280	COG2855	membrane
AB431_16285	COG2134	cdp-diacylglycerol pyrophosphatase
AB431_16305	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AB431_16305	COG0778	Nitroreductase
AB431_16420	COG3250	beta-galactosidase activity
AB431_16425	COG0697	spore germination
AB431_16435	COG0560	Phosphoserine phosphatase
AB431_16460	COG2070	2-Nitropropane dioxygenase
AB431_16485	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_16495	COG2124	cytochrome p450
AB431_16555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB431_16565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB431_16575	COG1605	Chorismate mutase
AB431_16585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_16615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AB431_16640	COG0438	transferase activity, transferring glycosyl groups
AB431_16650	COG0412	Dienelactone hydrolase
AB431_16660	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_16670	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
AB431_16690	COG5651	PPE family
AB431_16700	COG0174	glutamine synthetase
AB431_16715	COG2193	ferroxidase activity
AB431_16725	COG1024	Enoyl-CoA hydratase
AB431_16800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_16825	COG0183	Belongs to the thiolase family
AB431_16845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_16850	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AB431_16875	COG2261	transglycosylase associated protein
AB431_16900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_16915	COG2205	protein histidine kinase activity
AB431_16920	COG0829	nickel cation binding
AB431_16925	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AB431_16935	COG0804	urea catabolic process
AB431_16970	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AB431_16980	COG1253	flavin adenine dinucleotide binding
AB431_16985	COG1253	flavin adenine dinucleotide binding
AB431_17010	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AB431_17010	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AB431_17035	COG0509	glycine decarboxylation via glycine cleavage system
AB431_17075	COG3976	FMN-binding domain protein
AB431_17075	COG1053	succinate dehydrogenase
AB431_17100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB431_17105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB431_17105	COG4651	solute:proton antiporter activity
AB431_17120	COG2272	Belongs to the type-B carboxylesterase lipase family
AB431_17130	COG2076	Multidrug Resistance protein
AB431_17175	COG4266	Belongs to the allantoicase family
AB431_17185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AB431_17200	COG1335	isochorismatase
AB431_17210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB431_17220	COG1309	transcriptional regulator
AB431_17230	COG3046	protein related to deoxyribodipyrimidine photolyase
AB431_17295	COG0477	Major facilitator Superfamily
AB431_17300	COG1490	D-aminoacyl-tRNA deacylase activity
AB431_17315	COG1960	acyl-CoA dehydrogenase activity
AB431_17320	COG1960	acyl-CoA dehydrogenase activity
AB431_17325	COG0673	inositol 2-dehydrogenase activity
AB431_17335	COG1960	acyl-CoA dehydrogenase activity
AB431_17340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_17345	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_17350	COG2072	flavoprotein involved in K transport
AB431_17360	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_17375	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_17385	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_17390	COG1024	Enoyl-CoA hydratase
AB431_17400	COG0531	amino acid
AB431_17445	COG2252	PERMEase
AB431_17510	COG0277	FAD linked oxidase domain protein
AB431_17535	COG1309	transcriptional regulator
AB431_17545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_17560	COG4689	acetoacetate decarboxylase
AB431_17595	COG0798	PFAM Bile acid sodium symporter
AB431_17600	COG0640	Transcriptional regulator
AB431_17610	COG0640	Transcriptional regulator
AB431_17615	COG2801	Transposase and inactivated derivatives
AB431_17615	COG3415	Transposase
AB431_17675	COG0582	viral genome integration into host DNA
AB431_17700	COG1160	GTP binding
AB431_17705	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AB431_17715	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AB431_17720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AB431_17735	COG0494	nUDIX hydrolase
AB431_17740	COG0504	CTP synthase activity
AB431_17775	COG0647	UMP catabolic process
AB431_17805	COG2094	Belongs to the DNA glycosylase MPG family
AB431_17810	COG1131	(ABC) transporter
AB431_17830	COG2835	tetraacyldisaccharide 4'-kinase activity
AB431_17845	COG0488	(ABC) transporter
AB431_17865	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AB431_17870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AB431_17875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AB431_17880	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AB431_17890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB431_17890	COG0072	phenylalanine-tRNA ligase activity
AB431_17895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AB431_17900	COG0069	glutamate synthase activity
AB431_17940	COG1960	acyl-CoA dehydrogenase activity
AB431_17945	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AB431_17950	COG2080	2 iron, 2 sulfur cluster binding
AB431_17955	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AB431_17965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AB431_17970	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AB431_18000	COG4221	oxidoreductase activity
AB431_18010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB431_18035	COG0598	Magnesium transport protein CorA
AB431_18050	COG1573	uracil-dna glycosylase
AB431_18070	COG1285	pathogenesis
AB431_18140	COG1872	DUF167
AB431_18150	COG0410	ABC transporter
AB431_18155	COG0411	ABC transporter
AB431_18185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AB431_18200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB431_18225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB431_18235	COG1271	oxidase subunit
AB431_18240	COG1294	oxidase, subunit
AB431_18245	COG4988	ABC transporter
AB431_18250	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AB431_18265	COG1946	Acyl-CoA thioesterase
AB431_18280	COG0067	glutamate synthase
AB431_18280	COG0070	glutamate synthase
AB431_18280	COG0069	glutamate synthase activity
AB431_18360	COG0477	Major facilitator Superfamily
AB431_18370	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AB431_18380	COG1410	methionine synthase
AB431_18380	COG0646	methionine synthase
AB431_18390	COG1960	acyl-CoA dehydrogenase activity
AB431_18395	COG1960	acyl-CoA dehydrogenase activity
AB431_18400	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_18410	COG1218	3'(2'),5'-bisphosphate nucleotidase
AB431_18430	COG1968	undecaprenyl-diphosphatase activity
AB431_18450	COG0167	dihydroorotate dehydrogenase activity
AB431_18460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB431_18495	COG0861	Integral membrane protein TerC family
AB431_18500	COG0589	response to stress
AB431_18520	COG3290	protein histidine kinase activity
AB431_18550	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_18555	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AB431_18555	COG0519	Catalyzes the synthesis of GMP from XMP
AB431_18560	COG0469	pyruvate kinase activity
AB431_18615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AB431_18625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AB431_18640	COG0768	penicillin binding
AB431_18650	COG0275	rRNA processing
AB431_18700	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AB431_18715	COG5650	phosphatidylinositol metabolic process
AB431_18730	COG0003	Pfam Anion-transporting ATPase
AB431_18785	COG1845	cytochrome c oxidase, subunit III
AB431_18880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AB431_18885	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AB431_18915	COG0321	lipoyl(octanoyl) transferase activity
AB431_18945	COG0174	glutamine synthetase
AB431_18950	COG3706	GGDEF domain
AB431_18960	COG2259	Doxx family
AB431_18975	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AB431_18980	COG0174	glutamine synthetase
AB431_18995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB431_19005	COG1024	Enoyl-CoA hydratase
AB431_19050	COG0492	ferredoxin-NADP+ reductase activity
AB431_19055	COG0406	alpha-ribazole phosphatase activity
AB431_19055	COG0328	RNA-DNA hybrid ribonuclease activity
AB431_19085	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AB431_19135	COG1309	transcriptional regulator
AB431_19140	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_19160	COG1309	transcriptional regulator
AB431_19190	COG2070	2-Nitropropane dioxygenase
AB431_19240	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AB431_19250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AB431_19255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AB431_19260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AB431_19365	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_19385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AB431_19410	COG2226	methyltransferase
AB431_19440	COG0747	negative chemotaxis
AB431_19455	COG4172	Belongs to the ABC transporter superfamily
AB431_19485	COG2409	Drug exporters of the RND superfamily
AB431_19485	COG1033	growth of symbiont in host cell
AB431_19515	COG1733	regulation of RNA biosynthetic process
AB431_19540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_19550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB431_19555	COG4521	taurine ABC transporter
AB431_19560	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AB431_19575	COG2409	Drug exporters of the RND superfamily
AB431_19575	COG1033	growth of symbiont in host cell
AB431_19620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_19665	COG1175	transmembrane transport
AB431_19670	COG0395	ABC-type sugar transport system, permease component
AB431_19695	COG2814	Major facilitator Superfamily
AB431_19700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_19705	COG3781	membrane
AB431_19715	COG1960	acyl-CoA dehydrogenase activity
AB431_19745	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AB431_19760	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AB431_19785	COG0358	DNA primase activity
AB431_19790	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AB431_19805	COG0423	glycine-tRNA ligase activity
AB431_19825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AB431_19845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB431_19865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AB431_19880	COG2124	cytochrome p450
AB431_19885	COG2197	response regulator
AB431_19895	COG0484	heat shock protein binding
AB431_19900	COG1420	regulation of RNA biosynthetic process
AB431_19910	COG2205	protein histidine kinase activity
AB431_19915	COG0745	RESPONSE REGULATOR receiver
AB431_19920	COG0659	secondary active sulfate transmembrane transporter activity
AB431_19935	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB431_19935	COG0473	3-isopropylmalate dehydrogenase activity
AB431_19965	COG4208	sulfate ABC transporter
AB431_19970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AB431_19975	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AB431_19985	COG3387	PFAM Glycoside hydrolase 15-related
AB431_19995	COG2814	Major facilitator Superfamily
AB431_20010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AB431_20020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AB431_20020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB431_20035	COG0531	amino acid
AB431_20045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_20075	COG0667	Aldo Keto reductase
AB431_20090	COG0174	glutamine synthetase
AB431_20095	COG1234	tRNA 3'-trailer cleavage
AB431_20105	COG1305	Transglutaminase-like
AB431_20135	COG1555	photosystem II stabilization
AB431_20135	COG1596	polysaccharide export
AB431_20145	COG2353	YceI-like domain
AB431_20155	COG2755	lipolytic protein G-D-S-L family
AB431_20160	COG0406	alpha-ribazole phosphatase activity
AB431_20165	COG0799	negative regulation of ribosome biogenesis
AB431_20170	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AB431_20175	COG0657	acetylesterase activity
AB431_20175	COG5651	PPE family
AB431_20185	COG0542	response to heat
AB431_20190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AB431_20210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB431_20225	COG1335	isochorismatase
AB431_20240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AB431_20245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AB431_20250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AB431_20255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AB431_20260	COG1530	ribonuclease E activity
AB431_20265	COG0105	UTP biosynthetic process
AB431_20275	COG0285	dihydrofolate synthase activity
AB431_20280	COG0525	valine-tRNA ligase activity
AB431_20285	COG3268	Saccharopine dehydrogenase
AB431_20290	COG1506	peptidase
AB431_20290	COG0823	Involved in the tonB-independent uptake of proteins
AB431_20300	COG1388	LysM domain
AB431_20305	COG1388	LysM domain
AB431_20310	COG0746	molybdenum cofactor guanylyltransferase activity
AB431_20315	COG1013	pyruvate-flavodoxin oxidoreductase activity
AB431_20320	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AB431_20320	COG0674	pyruvate-flavodoxin oxidoreductase activity
AB431_20325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB431_20330	COG1609	Transcriptional regulator
AB431_20340	COG0673	inositol 2-dehydrogenase activity
AB431_20350	COG0673	inositol 2-dehydrogenase activity
AB431_20360	COG1172	Belongs to the binding-protein-dependent transport system permease family
AB431_20370	COG1609	Transcriptional regulator
AB431_20375	COG0673	inositol 2-dehydrogenase activity
AB431_20410	COG3718	enzyme involved in inositol metabolism
AB431_20415	COG3962	Belongs to the TPP enzyme family
AB431_20425	COG0673	inositol 2-dehydrogenase activity
AB431_20430	COG1082	Xylose isomerase domain protein TIM barrel
AB431_20445	COG0412	Dienelactone hydrolase
AB431_20465	COG0583	DNA-binding transcription factor activity
AB431_20505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AB431_20520	COG0544	peptidyl-prolyl cis-trans isomerase activity
AB431_20565	COG1231	oxidoreductase activity
AB431_20630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AB431_20645	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AB431_20665	COG0366	Alpha amylase catalytic
AB431_20685	COG2902	Dehydrogenase
AB431_20735	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_20855	COG2205	protein histidine kinase activity
AB431_20860	COG0745	RESPONSE REGULATOR receiver
AB431_20875	COG2801	Transposase and inactivated derivatives
AB431_20875	COG3415	Transposase
AB431_20890	COG2124	cytochrome p450
AB431_20895	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_20910	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_20925	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_20940	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_20965	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_20980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB431_21000	COG1595	DNA-templated transcription, initiation
AB431_21010	COG1304	FMN binding
AB431_21015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AB431_21020	COG1335	isochorismatase
AB431_21050	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB431_21075	COG1960	acyl-CoA dehydrogenase activity
AB431_21085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AB431_21100	COG1506	peptidase
AB431_21115	COG0300	oxidoreductase activity
AB431_21120	COG0433	COG0433 Predicted ATPase
AB431_21180	COG2271	Major facilitator Superfamily
AB431_21200	COG0640	Transcriptional regulator
AB431_21205	COG0346	lactoylglutathione lyase activity
AB431_21220	COG3757	hydrolase, family 25
AB431_21225	COG3842	ATPase activity
AB431_21230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AB431_21235	COG1176	ABC-type spermidine putrescine transport system, permease component I
AB431_21240	COG1177	transmembrane transport
AB431_21255	COG1960	acyl-CoA dehydrogenase activity
AB431_21260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB431_21265	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AB431_21320	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_21360	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_21415	COG2124	cytochrome p450
AB431_21420	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_21425	COG3383	formate dehydrogenase (NAD+) activity
AB431_21460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB431_21465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB431_21475	COG1053	succinate dehydrogenase
AB431_21480	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_21485	COG1024	Enoyl-CoA hydratase
AB431_21505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_21525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AB431_21530	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_21555	COG0183	Belongs to the thiolase family
AB431_21605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_21635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB431_21640	COG0183	Belongs to the thiolase family
AB431_21650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_21660	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_21665	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_21685	COG1960	acyl-CoA dehydrogenase activity
AB431_21690	COG1960	acyl-CoA dehydrogenase activity
AB431_21750	COG2124	cytochrome p450
AB431_21770	COG1960	acyl-CoA dehydrogenase activity
AB431_21775	COG0183	Belongs to the thiolase family
AB431_21780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_21800	COG4638	Rieske (2fe-2S)
AB431_21810	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AB431_21820	COG1960	acyl-CoA dehydrogenase activity
AB431_21825	COG1960	acyl-CoA dehydrogenase activity
AB431_21855	COG1960	acyl-CoA dehydrogenase activity
AB431_21860	COG1960	acyl-CoA dehydrogenase activity
AB431_21875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_21880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_21885	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AB431_21910	COG2350	Protein conserved in bacteria
AB431_21925	COG0300	oxidoreductase activity
AB431_22015	COG2814	Major facilitator Superfamily
AB431_22025	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AB431_22035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AB431_22070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AB431_22075	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AB431_22100	COG0366	Alpha amylase catalytic
AB431_22105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AB431_22120	COG0183	Belongs to the thiolase family
AB431_22135	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AB431_22140	COG2972	Histidine kinase
AB431_22140	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AB431_22180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AB431_22200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AB431_22205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AB431_22210	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AB431_22215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AB431_22215	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AB431_22220	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AB431_22225	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AB431_22230	COG0356	it plays a direct role in the translocation of protons across the membrane
AB431_22240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AB431_22250	COG2890	protein-(glutamine-N5) methyltransferase activity
AB431_22265	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_22270	COG1309	transcriptional regulator
AB431_22290	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AB431_22295	COG0460	homoserine dehydrogenase
AB431_22300	COG0019	diaminopimelate decarboxylase activity
AB431_22305	COG0018	arginyl-trna synthetase
AB431_22340	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_22345	COG0604	alcohol dehydrogenase
AB431_22345	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_22345	COG3321	synthase
AB431_22365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB431_22390	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AB431_22390	COG2755	lipolytic protein G-D-S-L family
AB431_22395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AB431_22395	COG2755	lipolytic protein G-D-S-L family
AB431_22420	COG1819	glycosyl
AB431_22425	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AB431_22425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB431_22450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AB431_22450	COG2755	lipolytic protein G-D-S-L family
AB431_22555	COG3321	synthase
AB431_22555	COG0604	alcohol dehydrogenase
AB431_22560	COG2070	2-Nitropropane dioxygenase
AB431_22560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AB431_22745	COG1132	(ABC) transporter
AB431_22795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_22810	COG0277	FAD linked oxidase domain protein
AB431_22815	COG0596	Alpha beta hydrolase
AB431_22820	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AB431_22825	COG4638	Rieske (2fe-2S)
AB431_22870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AB431_22875	COG0277	FAD linked oxidase domain protein
AB431_22945	COG2814	Major facilitator Superfamily
AB431_22955	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB431_22955	COG0567	Dehydrogenase, E1 component
AB431_22985	COG0598	Magnesium transport protein CorA
AB431_23035	COG2239	Acts as a magnesium transporter
AB431_23060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB431_23065	COG5662	AntiSigma factor
AB431_23080	COG1309	transcriptional regulator
AB431_23085	COG1131	(ABC) transporter
AB431_23090	COG3559	Exporter of polyketide antibiotics
AB431_23105	COG1309	transcriptional regulator
AB431_23125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AB431_23130	COG0297	glycogen (starch) synthase activity
AB431_23135	COG0519	Catalyzes the synthesis of GMP from XMP
AB431_23145	COG0463	Glycosyl transferase, family 2
AB431_23160	COG1611	Belongs to the LOG family
AB431_23170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB431_23190	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_23215	COG0438	transferase activity, transferring glycosyl groups
AB431_23255	COG0506	proline dehydrogenase activity
AB431_23260	COG1012	belongs to the aldehyde dehydrogenase family
AB431_23280	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AB431_23300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AB431_23360	COG1674	ftsk spoiiie
AB431_23370	COG1404	Belongs to the peptidase S8 family
AB431_23420	COG0202	RNA polymerase activity
AB431_23425	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AB431_23430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AB431_23435	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AB431_23445	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AB431_23450	COG3634	alkyl hydroperoxide reductase activity
AB431_23455	COG3852	Histidine kinase
AB431_23475	COG1088	dTDP-glucose 4,6-dehydratase activity
AB431_23485	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AB431_23490	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AB431_23495	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AB431_23540	COG0672	)-iron permease
AB431_23545	COG2822	iron ion transport
AB431_23550	COG2837	iron assimilation
AB431_23555	COG3956	TIGRFAM MazG family protein
AB431_23570	COG1309	transcriptional regulator
AB431_23605	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AB431_23610	COG0193	aminoacyl-tRNA hydrolase activity
AB431_23635	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_23640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AB431_23645	COG0515	serine threonine protein kinase
AB431_23650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AB431_23655	COG3583	domain protein
AB431_23660	COG0084	hydrolase, TatD family'
AB431_23675	COG1595	DNA-templated transcription, initiation
AB431_23700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_23710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_23715	COG2072	flavoprotein involved in K transport
AB431_23720	COG2072	flavoprotein involved in K transport
AB431_23730	COG2235	arginine
AB431_23760	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AB431_23775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AB431_23780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AB431_23780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB431_23790	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_23795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB431_23865	COG0714	Associated with various cellular activities
AB431_23935	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AB431_23940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AB431_23965	COG0521	Mo-molybdopterin cofactor biosynthetic process
AB431_23965	COG0315	cyclic pyranopterin monophosphate synthase activity
AB431_23970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB431_24000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AB431_24015	COG1024	Enoyl-CoA hydratase
AB431_24030	COG4867	von Willebrand factor, type A
AB431_24085	COG0045	succinate-CoA ligase (ADP-forming) activity
AB431_24090	COG0739	heme binding
AB431_24100	COG0671	phosphoesterase, PA-phosphatase related
AB431_24115	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AB431_24115	COG2755	lipolytic protein G-D-S-L family
AB431_24135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AB431_24140	COG1950	PFAM Membrane protein of
AB431_24150	COG0477	Major facilitator Superfamily
AB431_24195	COG0328	RNA-DNA hybrid ribonuclease activity
AB431_24205	COG1793	dna ligase
AB431_24205	COG3285	dna ligase
AB431_24215	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AB431_24255	COG1595	DNA-templated transcription, initiation
AB431_24265	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AB431_24270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_24290	COG2770	Histidine kinase
AB431_24290	COG2208	phosphoserine phosphatase activity
AB431_24305	COG0183	Belongs to the thiolase family
AB431_24340	COG0488	(ABC) transporter
AB431_24395	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AB431_24430	COG1132	(ABC) transporter
AB431_24435	COG1132	(ABC) transporter
AB431_24450	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_24490	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_24500	COG0545	Peptidyl-prolyl cis-trans isomerase
AB431_24505	COG2188	Transcriptional regulator
AB431_24510	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_24515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AB431_24535	COG1846	Transcriptional regulator
AB431_24540	COG0477	Major facilitator Superfamily
AB431_24550	COG1309	transcriptional regulator
AB431_24555	COG1309	transcriptional regulator
AB431_24590	COG3396	Phenylacetate-CoA oxygenase
AB431_24645	COG0435	Glutathione S-transferase
AB431_24650	COG1278	Cold shock
AB431_24655	COG3304	Inner membrane component domain
AB431_24680	COG0521	Mo-molybdopterin cofactor biosynthetic process
AB431_24700	COG1061	Type III restriction enzyme res subunit
AB431_24710	COG0183	Belongs to the thiolase family
AB431_24720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_24725	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_24735	COG0183	Belongs to the thiolase family
AB431_24750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB431_24780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_24800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_24830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB431_24860	COG1902	pentaerythritol trinitrate reductase activity
AB431_24865	COG1403	HNH endonuclease
AB431_24875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AB431_24905	COG1309	transcriptional regulator
AB431_24915	COG2072	flavoprotein involved in K transport
AB431_24925	COG4638	Rieske (2fe-2S)
AB431_24935	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AB431_24935	COG5479	isomerase activity
AB431_24955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_24970	COG0243	molybdopterin cofactor binding
AB431_24975	COG0183	Belongs to the thiolase family
AB431_24980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_24995	COG1960	acyl-CoA dehydrogenase activity
AB431_25005	COG1960	acyl-CoA dehydrogenase activity
AB431_25035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB431_25040	COG0300	oxidoreductase activity
AB431_25055	COG0183	Belongs to the thiolase family
AB431_25060	COG1024	Enoyl-CoA hydratase
AB431_25065	COG2186	Transcriptional regulator
AB431_25075	COG1024	Enoyl-CoA hydratase
AB431_25080	COG1024	Enoyl-CoA hydratase
AB431_25090	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_25110	COG1960	acyl-CoA dehydrogenase activity
AB431_25115	COG0183	Belongs to the thiolase family
AB431_25125	COG1960	acyl-CoA dehydrogenase activity
AB431_25130	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_25140	COG2072	flavoprotein involved in K transport
AB431_25150	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_25155	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_25160	COG1309	transcriptional regulator
AB431_25170	COG1902	pentaerythritol trinitrate reductase activity
AB431_25200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB431_25240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AB431_25265	COG0745	RESPONSE REGULATOR receiver
AB431_25285	COG2897	thiosulfate sulfurtransferase activity
AB431_25325	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AB431_25340	COG0702	epimerase
AB431_25390	COG1362	aminopeptidase activity
AB431_25395	COG2837	iron assimilation
AB431_25405	COG0047	phosphoribosylformylglycinamidine synthase activity
AB431_25410	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AB431_25435	COG0386	Belongs to the glutathione peroxidase family
AB431_25460	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AB431_25490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AB431_25555	COG4638	Rieske (2fe-2S)
AB431_25560	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_25575	COG1960	acyl-CoA dehydrogenase activity
AB431_25580	COG1960	acyl-CoA dehydrogenase activity
AB431_25590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_25600	COG0183	Belongs to the thiolase family
AB431_25605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_25610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_25615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB431_25645	COG1960	acyl-CoA dehydrogenase activity
AB431_25650	COG1960	acyl-CoA dehydrogenase activity
AB431_25670	COG3386	PFAM SMP-30 Gluconolaconase
AB431_25680	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_25685	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_25700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_25705	COG1024	Enoyl-CoA hydratase
AB431_25715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AB431_25720	COG1960	acyl-CoA dehydrogenase activity
AB431_25725	COG1024	Enoyl-CoA hydratase
AB431_25730	COG1024	Enoyl-CoA hydratase
AB431_25750	COG0022	dehydrogenase e1 component
AB431_25785	COG1309	transcriptional regulator
AB431_25790	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_25795	COG1024	Enoyl-CoA hydratase
AB431_25810	COG1960	acyl-CoA dehydrogenase activity
AB431_25815	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_25820	COG1309	transcriptional regulator
AB431_25830	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_25845	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_25885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_25900	COG2124	cytochrome p450
AB431_25925	COG3510	cephalosporin hydroxylase
AB431_25935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AB431_25975	COG4221	oxidoreductase activity
AB431_25980	COG2124	cytochrome p450
AB431_26005	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_26020	COG5002	protein histidine kinase activity
AB431_26020	COG5000	phosphorelay sensor kinase activity
AB431_26025	COG0745	RESPONSE REGULATOR receiver
AB431_26040	COG4251	negative regulation of phosphorylation
AB431_26040	COG3706	GGDEF domain
AB431_26040	COG2203	Gaf domain
AB431_26040	COG5001	Diguanylate cyclase
AB431_26125	COG1316	TRANSCRIPTIONal
AB431_26130	COG2084	Dehydrogenase
AB431_26170	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB431_26205	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_26215	COG1960	acyl-CoA dehydrogenase activity
AB431_26220	COG1960	acyl-CoA dehydrogenase activity
AB431_26235	COG0028	Belongs to the TPP enzyme family
AB431_26245	COG2070	2-Nitropropane dioxygenase
AB431_26265	COG2124	cytochrome p450
AB431_26275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_26315	COG4638	Rieske (2fe-2S)
AB431_26350	COG0514	ATP-dependent DNA helicase (RecQ)
AB431_26355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AB431_26360	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AB431_26370	COG1053	succinate dehydrogenase
AB431_26400	COG2030	dehydratase
AB431_26405	COG1960	acyl-CoA dehydrogenase activity
AB431_26410	COG1960	acyl-CoA dehydrogenase activity
AB431_26415	COG2124	cytochrome p450
AB431_26420	COG0183	Belongs to the thiolase family
AB431_26440	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_26445	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_26450	COG1024	Enoyl-CoA hydratase
AB431_26485	COG0183	Belongs to the thiolase family
AB431_26490	COG1309	transcriptional regulator
AB431_26500	COG1960	acyl-CoA dehydrogenase activity
AB431_26505	COG0318	PFAM AMP-dependent synthetase and ligase
AB431_26510	COG1960	acyl-CoA dehydrogenase activity
AB431_26515	COG1960	acyl-CoA dehydrogenase activity
AB431_26525	COG0436	Aminotransferase
AB431_26530	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_26550	COG0346	lactoylglutathione lyase activity
AB431_26570	COG1960	acyl-CoA dehydrogenase activity
AB431_26575	COG1309	transcriptional regulator
AB431_26585	COG1609	Transcriptional regulator
AB431_26595	COG1121	(ABC) transporter
AB431_26600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AB431_26625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB431_26630	COG0215	cysteine-tRNA ligase activity
AB431_26640	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AB431_26645	COG1329	Transcriptional regulator
AB431_26650	COG2847	Copper chaperone PCu(A)C
AB431_26660	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AB431_26675	COG1194	a g-specific adenine glycosylase
AB431_26690	COG0596	Alpha beta hydrolase
AB431_26720	COG0393	Putative heavy-metal-binding
AB431_26725	COG0542	response to heat
AB431_26735	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AB431_26745	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AB431_26750	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AB431_26755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AB431_26785	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AB431_26790	COG0302	gtp cyclohydrolase
AB431_26800	COG2267	carboxylic ester hydrolase activity
AB431_26810	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AB431_26825	COG0346	lactoylglutathione lyase activity
AB431_26830	COG2207	Transcriptional regulator
AB431_26830	COG3708	Transcriptional regulator
AB431_26875	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AB431_26880	COG1309	transcriptional regulator
AB431_26915	COG1215	transferase activity, transferring glycosyl groups
AB431_26935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB431_26950	COG0470	DNA polymerase III
AB431_26960	COG1754	DNA topoisomerase type I activity
AB431_26960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AB431_26970	COG1278	Cold shock
AB431_26975	COG1111	helicase
AB431_26975	COG1205	dead DEAH box helicase
AB431_27035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB431_27085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB431_27110	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AB431_27115	COG1408	metallophosphoesterase
AB431_27120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AB431_27130	COG0657	acetylesterase activity
AB431_27160	COG2890	protein-(glutamine-N5) methyltransferase activity
AB431_27170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_27195	COG0714	Associated with various cellular activities
AB431_27230	COG0569	domain protein
AB431_27230	COG0475	glutathione-regulated potassium exporter activity
AB431_27245	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_27250	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AB431_27265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AB431_27290	COG0477	Major facilitator Superfamily
AB431_27295	COG0745	RESPONSE REGULATOR receiver
AB431_27300	COG0642	Histidine kinase
AB431_27325	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AB431_27335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AB431_27340	COG3572	ergothioneine biosynthetic process
AB431_27350	COG1764	response to oxidative stress
AB431_27415	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AB431_27420	COG2218	PFAM glutamate synthase alpha subunit domain protein
AB431_27425	COG0069	glutamate synthase activity
AB431_27430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB431_27465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AB431_27470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AB431_27475	COG1492	cobalamin metabolic process
AB431_27485	COG2200	EAL domain
AB431_27495	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AB431_27500	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB431_27515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB431_27525	COG1309	transcriptional regulator
AB431_27540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB431_27580	COG0515	serine threonine protein kinase
AB431_27580	COG2815	serine threonine protein kinase
AB431_27590	COG1793	dna ligase
AB431_27600	COG1937	Protein conserved in bacteria
AB431_27605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB431_27610	COG0730	response to heat
AB431_27615	COG2193	ferroxidase activity
AB431_27635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB431_27645	COG0765	amino acid transport
AB431_27650	COG1126	abc transporter atp-binding protein
AB431_27655	COG1231	oxidoreductase activity
AB431_27660	COG2124	cytochrome p450
AB431_27665	COG0343	queuine tRNA-ribosyltransferase activity
AB431_27670	COG0596	Alpha beta hydrolase
AB431_27710	COG0287	Prephenate dehydrogenase
AB431_27720	COG1174	glycine betaine transport
AB431_27725	COG1174	glycine betaine transport
AB431_27740	COG5416	Lipopolysaccharide assembly protein A domain
AB431_27760	COG1960	acyl-CoA dehydrogenase activity
AB431_27775	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_27795	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AB431_27805	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AB431_27805	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AB431_27815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AB431_27820	COG2205	protein histidine kinase activity
AB431_27825	COG0745	RESPONSE REGULATOR receiver
AB431_27850	COG1960	acyl-CoA dehydrogenase activity
AB431_27855	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_27885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AB431_27900	COG1045	serine acetyltransferase
AB431_27930	COG1063	alcohol dehydrogenase
AB431_27955	COG1216	Glycosyl transferase, family 2
AB431_27985	COG0277	FAD linked oxidase domain protein
AB431_27990	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_28055	COG0243	molybdopterin cofactor binding
AB431_28060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AB431_28090	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AB431_28100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AB431_28105	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AB431_28110	COG0671	phosphoesterase, PA-phosphatase related
AB431_28115	COG1216	Glycosyl transferase, family 2
AB431_28135	COG0561	phosphatase activity
AB431_28145	COG0204	Acyl-transferase
AB431_28225	COG1316	TRANSCRIPTIONal
AB431_28245	COG2119	membrane
AB431_28290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB431_28295	COG2072	flavoprotein involved in K transport
AB431_28305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB431_28310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AB431_28315	COG1796	DNA polymerase
AB431_28315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AB431_28325	COG0659	secondary active sulfate transmembrane transporter activity
AB431_28345	COG0069	glutamate synthase activity
AB431_28345	COG0067	glutamate synthase
AB431_28345	COG0070	glutamate synthase
AB431_28350	COG2894	cell division
AB431_28360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB431_28380	COG1404	Belongs to the peptidase S8 family
AB431_28390	COG2894	cell division
AB431_28450	COG1960	acyl-CoA dehydrogenase activity
AB431_28455	COG1960	acyl-CoA dehydrogenase activity
AB431_28465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_28470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB431_28475	COG1752	Esterase of the alpha-beta hydrolase superfamily
AB431_28485	COG1643	Atp-dependent helicase
AB431_28515	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AB431_28515	COG2755	lipolytic protein G-D-S-L family
AB431_28520	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_28540	COG2190	(PTS) system
AB431_28540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB431_28540	COG1263	PTS System
AB431_28545	COG2190	(PTS) system
AB431_28545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB431_28545	COG1263	PTS System
AB431_28550	COG0363	glucosamine-6-phosphate deaminase activity
AB431_28555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AB431_28630	COG0494	nUDIX hydrolase
AB431_28650	COG1063	alcohol dehydrogenase
AB431_28655	COG1414	Transcriptional regulator
AB431_28660	COG0346	lactoylglutathione lyase activity
AB431_28670	COG1309	transcriptional regulator
AB431_28680	COG1960	acyl-CoA dehydrogenase activity
AB431_28700	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_28715	COG3757	hydrolase, family 25
AB431_28750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AB431_28760	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_28775	COG1028	Short-chain dehydrogenase reductase Sdr
AB431_28790	COG2030	dehydratase
AB431_28795	COG2201	protein-glutamate methylesterase activity
AB431_28800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AB431_28805	COG5002	protein histidine kinase activity
AB431_28805	COG0784	Response regulator, receiver
AB431_28815	COG5001	Diguanylate cyclase
AB431_28815	COG3300	MHYT domain
AB431_28855	COG1960	acyl-CoA dehydrogenase activity
AB431_28945	COG0475	glutathione-regulated potassium exporter activity
AB431_28970	COG0187	DNA topoisomerase II activity
AB431_28975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AB431_29010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB431_29055	COG0305	Participates in initiation and elongation during chromosome replication
AB431_29060	COG0359	binds to the 23S rRNA
AB431_29070	COG0629	single-stranded DNA binding
AB431_29075	COG0360	Binds together with S18 to 16S ribosomal RNA
AB431_29095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB431_29115	COG1260	myo-inositol-1-phosphate synthase
AB431_29125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB431_29140	COG0765	amino acid transport
AB431_29145	COG1126	abc transporter atp-binding protein
AB431_29160	COG4221	oxidoreductase activity
AB431_29185	COG1309	transcriptional regulator
AB431_29190	COG1678	Uncharacterized ACR, COG1678
AB431_29195	COG2814	Major facilitator Superfamily
AB431_29240	COG1595	DNA-templated transcription, initiation
AB431_29260	COG3409	Peptidoglycan-binding domain 1 protein
AB431_29260	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB431_29275	COG1192	Involved in chromosome partitioning
AB431_29280	COG0357	Ribosomal RNA small subunit methyltransferase G
AB431_29290	COG0706	membrane insertase activity
AB431_29295	COG0594	ribonuclease P activity