locus-tag	class	description
C0092_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C0092_00115	COG1716	ATPase activity
C0092_00190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0092_00210	COG2814	Major facilitator Superfamily
C0092_00245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0092_00275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0092_00345	COG0277	FAD linked oxidase domain protein
C0092_00375	COG1309	transcriptional regulator
C0092_00380	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_00395	COG3344	reverse transcriptase
C0092_00410	COG1228	amidohydrolase
C0092_00430	COG1309	transcriptional regulator
C0092_00460	COG3260	NADH ubiquinone oxidoreductase 20
C0092_00470	COG0650	Formate hydrogenlyase subunit 4
C0092_00480	COG0651	ATP synthesis coupled electron transport
C0092_00485	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C0092_00485	COG3261	NADH dehydrogenase
C0092_00490	COG3832	glyoxalase III activity
C0092_00530	COG1403	HNH endonuclease
C0092_00535	COG1403	HNH endonuclease
C0092_00565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0092_00610	COG0657	acetylesterase activity
C0092_00620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C0092_00620	COG2755	lipolytic protein G-D-S-L family
C0092_00655	COG0583	DNA-binding transcription factor activity
C0092_00660	COG0028	Belongs to the TPP enzyme family
C0092_00695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0092_00735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0092_00745	COG0596	Alpha beta hydrolase
C0092_00790	COG0038	chloride channel
C0092_00795	COG1309	transcriptional regulator
C0092_00810	COG1012	belongs to the aldehyde dehydrogenase family
C0092_00815	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_00820	COG0604	alcohol dehydrogenase
C0092_00820	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_00820	COG3321	synthase
C0092_00845	COG3391	amine dehydrogenase activity
C0092_00850	COG2365	Tyrosine phosphatase family
C0092_00865	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C0092_00875	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C0092_00885	COG1309	transcriptional regulator
C0092_00890	COG5651	PPE family
C0092_00890	COG0657	acetylesterase activity
C0092_00895	COG0657	acetylesterase activity
C0092_00895	COG5651	PPE family
C0092_00900	COG0277	FAD linked oxidase domain protein
C0092_00905	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C0092_00925	COG1802	Transcriptional regulator
C0092_00935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0092_00940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0092_00965	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0092_01015	COG2267	carboxylic ester hydrolase activity
C0092_01030	COG1472	Belongs to the glycosyl hydrolase 3 family
C0092_01055	COG1937	Protein conserved in bacteria
C0092_01065	COG1376	ErfK ybiS ycfS ynhG family protein
C0092_01075	COG1132	(ABC) transporter
C0092_01090	COG0243	molybdopterin cofactor binding
C0092_01095	COG3590	peptidase
C0092_01135	COG2409	Drug exporters of the RND superfamily
C0092_01195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C0092_01215	COG1024	Enoyl-CoA hydratase
C0092_01230	COG0297	glycogen (starch) synthase activity
C0092_01250	COG1487	ribonuclease activity
C0092_01290	COG4981	capsule polysaccharide biosynthetic process
C0092_01300	COG1472	Belongs to the glycosyl hydrolase 3 family
C0092_01330	COG0183	Belongs to the thiolase family
C0092_01335	COG1960	acyl-CoA dehydrogenase activity
C0092_01355	COG1053	succinate dehydrogenase
C0092_01375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0092_01375	COG2146	nitrite reductase [NAD(P)H] activity
C0092_01395	COG5651	PPE family
C0092_01435	COG1984	allophanate hydrolase subunit 2
C0092_01455	COG2223	nitrite transmembrane transporter activity
C0092_01460	COG2161	toxin-antitoxin pair type II binding
C0092_01470	COG0318	PFAM AMP-dependent synthetase and ligase
C0092_01475	COG1960	acyl-CoA dehydrogenase activity
C0092_01490	COG0346	lactoylglutathione lyase activity
C0092_01585	COG1404	Belongs to the peptidase S8 family
C0092_01610	COG1368	sulfuric ester hydrolase activity
C0092_01615	COG3391	amine dehydrogenase activity
C0092_01655	COG0778	Nitroreductase
C0092_01665	COG0671	phosphoesterase, PA-phosphatase related
C0092_01735	COG0717	Belongs to the dCTP deaminase family
C0092_01740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C0092_01745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C0092_01760	COG2226	methyltransferase
C0092_01775	COG2226	methyltransferase
C0092_01785	COG1252	NADH dehydrogenase
C0092_01825	COG0247	lactate metabolic process
C0092_01825	COG2181	nitrate reductase activity
C0092_01900	COG0789	Transcriptional regulator
C0092_01910	COG5263	repeat protein
C0092_01910	COG5651	PPE family
C0092_01945	COG2239	Acts as a magnesium transporter
C0092_01990	COG0746	molybdenum cofactor guanylyltransferase activity
C0092_02030	COG3360	Dodecin
C0092_02075	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C0092_02090	COG1252	NADH dehydrogenase
C0092_02095	COG1403	HNH endonuclease
C0092_02140	COG1960	acyl-CoA dehydrogenase activity
C0092_02165	COG0604	alcohol dehydrogenase
C0092_02165	COG3321	synthase
C0092_02170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0092_02195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0092_02235	COG2234	aminopeptidase activity
C0092_02270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C0092_02320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0092_02340	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_02345	COG0459	protein refolding
C0092_02365	COG5343	regulation of RNA biosynthetic process
C0092_02380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0092_02430	COG1024	Enoyl-CoA hydratase
C0092_02435	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0092_02445	COG1505	serine-type exopeptidase activity
C0092_02505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0092_02530	COG2733	membrane
C0092_02705	COG0560	Phosphoserine phosphatase
C0092_02735	COG1648	precorrin-2 dehydrogenase activity
C0092_02735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0092_02765	COG2755	lipolytic protein G-D-S-L family
C0092_02765	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C0092_02795	COG1113	amino acid transport
C0092_02810	COG0406	alpha-ribazole phosphatase activity
C0092_02820	COG0785	Cytochrome C biogenesis protein
C0092_02830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0092_02855	COG3391	amine dehydrogenase activity
C0092_02870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C0092_02875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0092_02930	COG4221	oxidoreductase activity
C0092_02950	COG0318	PFAM AMP-dependent synthetase and ligase
C0092_02955	COG1228	amidohydrolase
C0092_03020	COG2072	flavoprotein involved in K transport
C0092_03035	COG2345	Transcriptional regulator
C0092_03050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0092_03125	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
C0092_03135	COG3537	Alpha-1,2-mannosidase
C0092_03155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0092_03180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0092_03190	COG1487	ribonuclease activity
C0092_03210	COG2002	toxin-antitoxin pair type II binding
C0092_03220	COG2972	Histidine kinase
C0092_03225	COG0745	RESPONSE REGULATOR receiver
C0092_03295	COG0653	protein targeting
C0092_03330	COG1085	galactose-1-phosphate uridylyltransferase
C0092_03335	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C0092_03375	COG1487	ribonuclease activity
C0092_03395	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C0092_03440	COG2030	dehydratase
C0092_03470	COG0081	regulation of translation
C0092_03475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0092_03485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0092_03635	COG1960	acyl-CoA dehydrogenase activity
C0092_03650	COG1024	Enoyl-CoA hydratase
C0092_03665	COG1510	regulation of RNA biosynthetic process
C0092_03745	COG0535	radical SAM domain protein
C0092_03860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C0092_03915	COG0200	Binds to the 23S rRNA
C0092_03920	COG0616	signal peptide processing
C0092_03925	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0092_03930	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0092_03935	COG0235	Class ii aldolase
C0092_03940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0092_03955	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0092_04025	COG0657	acetylesterase activity
C0092_04100	COG0406	alpha-ribazole phosphatase activity
C0092_04125	COG0745	RESPONSE REGULATOR receiver
C0092_04130	COG2205	protein histidine kinase activity
C0092_04165	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_04225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C0092_04255	COG0477	Major facilitator Superfamily
C0092_04280	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C0092_04300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0092_04305	COG2188	Transcriptional regulator
C0092_04310	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C0092_04315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0092_04335	COG2837	iron assimilation
C0092_04385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C0092_04430	COG0745	RESPONSE REGULATOR receiver
C0092_04480	COG0640	Transcriptional regulator
C0092_04485	COG0590	tRNA wobble adenosine to inosine editing
C0092_04495	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0092_04525	COG3391	amine dehydrogenase activity
C0092_04575	COG4106	trans-aconitate 2-methyltransferase activity
C0092_04580	COG0596	Alpha beta hydrolase
C0092_04600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C0092_04610	COG4585	Histidine kinase
C0092_04615	COG2132	Multicopper oxidase
C0092_04625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0092_04685	COG0183	Belongs to the thiolase family
C0092_04690	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0092_04690	COG1024	Enoyl-CoA hydratase
C0092_04720	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0092_04745	COG3304	Inner membrane component domain
C0092_04750	COG1278	Cold shock
C0092_04985	COG0183	Belongs to the thiolase family
C0092_05025	COG3328	transposase activity
C0092_05145	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C0092_05160	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C0092_05185	COG0739	heme binding
C0092_05190	COG0045	succinate-CoA ligase (ADP-forming) activity
C0092_05235	COG4867	von Willebrand factor, type A
C0092_05300	COG1024	Enoyl-CoA hydratase
C0092_05315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0092_05340	COG3391	amine dehydrogenase activity
C0092_05355	COG3391	amine dehydrogenase activity
C0092_05365	COG0745	RESPONSE REGULATOR receiver
C0092_05370	COG2205	protein histidine kinase activity
C0092_05370	COG2972	Histidine kinase
C0092_05375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0092_05380	COG0315	cyclic pyranopterin monophosphate synthase activity
C0092_05380	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0092_05420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C0092_05425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C0092_05465	COG4106	trans-aconitate 2-methyltransferase activity
C0092_05470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0092_05470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0092_05505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C0092_05520	COG0084	hydrolase, TatD family'
C0092_05550	COG0318	PFAM AMP-dependent synthetase and ligase
C0092_05585	COG1309	transcriptional regulator
C0092_05595	COG3956	TIGRFAM MazG family protein
C0092_05605	COG4948	Mandelate Racemase Muconate Lactonizing
C0092_05665	COG2205	protein histidine kinase activity
C0092_05670	COG0745	RESPONSE REGULATOR receiver
C0092_05695	COG0657	acetylesterase activity
C0092_05725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0092_05765	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_05820	COG0318	PFAM AMP-dependent synthetase and ligase
C0092_05900	COG0183	Belongs to the thiolase family
C0092_05910	COG0657	acetylesterase activity
C0092_05950	COG1331	Highly conserved protein containing a thioredoxin domain
C0092_05980	COG0657	acetylesterase activity
C0092_06025	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C0092_06110	COG0012	GTP binding
C0092_06160	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C0092_06170	COG0596	Alpha beta hydrolase
C0092_06185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C0092_06185	COG0574	Belongs to the PEP-utilizing enzyme family
C0092_06190	COG1403	HNH endonuclease
C0092_06195	COG3800	Transcriptional regulator
C0092_06195	COG1396	sequence-specific DNA binding
C0092_06200	COG2079	MmgE PrpD family protein
C0092_06230	COG0183	Belongs to the thiolase family
C0092_06250	COG1755	Isoprenylcysteine carboxyl methyltransferase
C0092_06265	COG1024	Enoyl-CoA hydratase
C0092_06270	COG1024	Enoyl-CoA hydratase
C0092_06275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C0092_06295	COG2409	Drug exporters of the RND superfamily
C0092_06300	COG2409	Drug exporters of the RND superfamily
C0092_06345	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0092_06355	COG3467	pyridoxamine 5'-phosphate
C0092_06405	COG1140	nitrate reductase beta subunit
C0092_06470	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0092_06470	COG1902	pentaerythritol trinitrate reductase activity
C0092_06480	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C0092_06495	COG3321	synthase
C0092_06495	COG0604	alcohol dehydrogenase
C0092_06495	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_06510	COG5651	PPE family
C0092_06520	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C0092_06520	COG2508	Transcriptional regulator
C0092_06525	COG1012	belongs to the aldehyde dehydrogenase family
C0092_06530	COG0506	proline dehydrogenase activity
C0092_06540	COG0596	Alpha beta hydrolase
C0092_06555	COG0318	PFAM AMP-dependent synthetase and ligase
C0092_06570	COG0657	acetylesterase activity
C0092_06575	COG5651	PPE family
C0092_06580	COG4842	Belongs to the WXG100 family
C0092_06600	COG0477	Major facilitator Superfamily
C0092_06625	COG1611	Belongs to the LOG family
C0092_06650	COG0519	Catalyzes the synthesis of GMP from XMP
C0092_06685	COG3559	Exporter of polyketide antibiotics
C0092_06690	COG1131	(ABC) transporter
C0092_06695	COG1309	transcriptional regulator
C0092_06715	COG5662	AntiSigma factor
C0092_06720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0092_06725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0092_06770	COG2239	Acts as a magnesium transporter
C0092_06805	COG0598	Magnesium transport protein CorA
C0092_06845	COG2026	Addiction module toxin, RelE StbE family
C0092_06850	COG2161	toxin-antitoxin pair type II binding
C0092_06855	COG0567	Dehydrogenase, E1 component
C0092_06855	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0092_06900	COG0277	FAD linked oxidase domain protein
C0092_06985	COG1132	(ABC) transporter
C0092_07260	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
C0092_07260	COG2972	Histidine kinase
C0092_07300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C0092_07495	COG5651	PPE family
C0092_07575	COG2226	methyltransferase
C0092_07655	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C0092_07660	COG2072	flavoprotein involved in K transport
C0092_07825	COG2272	Belongs to the type-B carboxylesterase lipase family
C0092_07830	COG0318	PFAM AMP-dependent synthetase and ligase
C0092_07860	COG1376	ErfK ybiS ycfS ynhG family protein
C0092_07915	COG0657	acetylesterase activity
C0092_07975	COG0657	acetylesterase activity
C0092_07980	COG0109	protoheme IX farnesyltransferase activity
C0092_07985	COG0657	acetylesterase activity
C0092_08015	COG1131	(ABC) transporter
C0092_08040	COG0396	ATPase activity
C0092_08055	COG2151	metal-sulfur cluster biosynthetic enzyme
C0092_08060	COG1960	acyl-CoA dehydrogenase activity
C0092_08080	COG3118	belongs to the thioredoxin family
C0092_08090	COG0488	(ABC) transporter
C0092_08100	COG1309	transcriptional regulator
C0092_08105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C0092_08115	COG3883	PFAM NLP P60 protein
C0092_08115	COG0791	NLP P60 protein
C0092_08125	COG0714	Associated with various cellular activities
C0092_08230	COG2226	methyltransferase
C0092_08235	COG3360	Dodecin
C0092_08270	COG4106	trans-aconitate 2-methyltransferase activity
C0092_08290	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C0092_08310	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C0092_08315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0092_08395	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_08395	COG0604	alcohol dehydrogenase
C0092_08395	COG3321	synthase
C0092_08425	COG2070	2-Nitropropane dioxygenase
C0092_08480	COG0300	oxidoreductase activity
C0092_08595	COG0791	NLP P60 protein
C0092_08595	COG3883	PFAM NLP P60 protein
C0092_08790	COG0483	inositol monophosphate 1-phosphatase activity
C0092_08795	COG0107	imidazoleglycerol-phosphate synthase activity
C0092_08805	COG0387	Pfam Sodium calcium exchanger
C0092_08865	COG1946	Acyl-CoA thioesterase
C0092_08870	COG0454	-acetyltransferase
C0092_08870	COG0456	acetyltransferase
C0092_08875	COG4988	ABC transporter
C0092_08880	COG4988	ABC transporter
C0092_08885	COG1294	oxidase, subunit
C0092_08890	COG1271	oxidase subunit
C0092_08980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0092_09030	COG0657	acetylesterase activity
C0092_09045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C0092_09055	COG3391	amine dehydrogenase activity
C0092_09105	COG3321	synthase
C0092_09105	COG0604	alcohol dehydrogenase
C0092_09110	COG0604	alcohol dehydrogenase
C0092_09110	COG3321	synthase
C0092_09115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0092_09115	COG4221	oxidoreductase activity
C0092_09115	COG0604	alcohol dehydrogenase
C0092_09115	COG3321	synthase
C0092_09120	COG0604	alcohol dehydrogenase
C0092_09120	COG0604	alcohol dehydrogenase
C0092_09120	COG3321	synthase
C0092_09120	COG3321	synthase
C0092_09135	COG0488	(ABC) transporter
C0092_09190	COG1960	acyl-CoA dehydrogenase activity
C0092_09195	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C0092_09215	COG2835	tetraacyldisaccharide 4'-kinase activity
C0092_09255	COG0647	UMP catabolic process
C0092_09295	COG0494	nUDIX hydrolase
C0092_09315	COG1113	amino acid transport
C0092_09320	COG5651	PPE family
C0092_09335	COG0659	secondary active sulfate transmembrane transporter activity
C0092_09350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C0092_09390	COG3246	L-lysine catabolic process to acetate
C0092_09430	COG1733	regulation of RNA biosynthetic process
C0092_09450	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0092_09540	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C0092_09550	COG1716	ATPase activity
C0092_09550	COG1131	(ABC) transporter
C0092_09550	COG0842	Transport permease protein
C0092_09565	COG0318	PFAM AMP-dependent synthetase and ligase
C0092_09580	COG5263	repeat protein
C0092_09580	COG5651	PPE family
C0092_09650	COG1937	Protein conserved in bacteria
C0092_09760	COG5651	PPE family
C0092_09770	COG5651	PPE family
C0092_09800	COG1404	Belongs to the peptidase S8 family
C0092_09840	COG0657	acetylesterase activity
C0092_09855	COG0657	acetylesterase activity
C0092_09965	COG0509	glycine decarboxylation via glycine cleavage system
C0092_09990	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C0092_09990	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C0092_10040	COG1253	flavin adenine dinucleotide binding
C0092_10045	COG1253	flavin adenine dinucleotide binding
C0092_10055	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C0092_10090	COG0830	nickel cation binding
C0092_10110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0092_10160	COG4221	oxidoreductase activity
C0092_10165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C0092_10175	COG0183	Belongs to the thiolase family
C0092_10240	COG0174	glutamine synthetase
C0092_10260	COG0300	oxidoreductase activity
C0092_10270	COG1652	LysM domain
C0092_10305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0092_10310	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0092_10335	COG2070	2-Nitropropane dioxygenase
C0092_10350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0092_10365	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C0092_10385	COG1950	PFAM Membrane protein of
C0092_10410	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C0092_10450	COG5651	PPE family
C0092_10450	COG5263	repeat protein
C0092_10455	COG5651	PPE family
C0092_10455	COG5263	repeat protein
C0092_10475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0092_10520	COG4977	sequence-specific DNA binding
C0092_10530	COG1960	acyl-CoA dehydrogenase activity
C0092_10535	COG1960	acyl-CoA dehydrogenase activity
C0092_10540	COG1024	Enoyl-CoA hydratase
C0092_10555	COG0543	2 iron, 2 sulfur cluster binding
C0092_10555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0092_10570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C0092_10570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C0092_10575	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_10580	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0092_10590	COG0653	protein targeting
C0092_10635	COG4691	Plasmid stability protein
C0092_10695	COG1309	transcriptional regulator
C0092_10740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0092_10820	COG1872	DUF167
C0092_10865	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_10900	COG0589	response to stress
C0092_11030	COG2442	InterPro IPR007367
C0092_11045	COG1396	sequence-specific DNA binding
C0092_11050	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
C0092_11115	COG0640	Transcriptional regulator
C0092_11130	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0092_11135	COG3842	ATPase activity
C0092_11140	COG0395	ABC-type sugar transport system, permease component
C0092_11145	COG1175	transmembrane transport
C0092_11160	COG1335	isochorismatase
C0092_11215	COG0412	Dienelactone hydrolase
C0092_11240	COG0803	Belongs to the bacterial solute-binding protein 9 family
C0092_11260	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0092_11310	COG0300	oxidoreductase activity
C0092_11380	COG2801	Transposase and inactivated derivatives
C0092_11445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C0092_11450	COG4279	zinc finger
C0092_11455	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
C0092_11465	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
C0092_11560	COG5651	PPE family
C0092_11565	COG0646	methionine synthase
C0092_11565	COG1410	methionine synthase
C0092_11590	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_11655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0092_11725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C0092_11775	COG0768	penicillin binding
C0092_11855	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C0092_11885	COG0003	Pfam Anion-transporting ATPase
C0092_11900	COG1022	Amp-dependent synthetase and ligase
C0092_12010	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C0092_12035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C0092_12055	COG0321	lipoyl(octanoyl) transferase activity
C0092_12125	COG0406	alpha-ribazole phosphatase activity
C0092_12125	COG0328	RNA-DNA hybrid ribonuclease activity
C0092_12145	COG3744	PilT protein domain protein
C0092_12315	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C0092_12320	COG4221	oxidoreductase activity
C0092_12390	COG0584	glycerophosphoryl diester phosphodiesterase
C0092_12575	COG2442	InterPro IPR007367
C0092_12645	COG0395	ABC-type sugar transport system, permease component
C0092_12660	COG0531	amino acid
C0092_12665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0092_12670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0092_12675	COG1834	amidinotransferase
C0092_12680	COG1522	sequence-specific DNA binding
C0092_12710	COG2223	nitrite transmembrane transporter activity
C0092_12745	COG1045	serine acetyltransferase
C0092_12760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C0092_12940	COG0657	acetylesterase activity
C0092_12985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0092_13000	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C0092_13000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0092_13005	COG1021	2,3-dihydroxybenzoate-AMP ligase
C0092_13065	COG1297	OPT oligopeptide transporter protein
C0092_13090	COG4208	sulfate ABC transporter
C0092_13100	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C0092_13115	COG3387	PFAM Glycoside hydrolase 15-related
C0092_13160	COG1305	Transglutaminase-like
C0092_13190	COG1555	photosystem II stabilization
C0092_13190	COG1596	polysaccharide export
C0092_13205	COG2755	lipolytic protein G-D-S-L family
C0092_13215	COG0799	negative regulation of ribosome biogenesis
C0092_13220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C0092_13250	COG0542	response to heat
C0092_13280	COG5651	PPE family
C0092_13300	COG0668	transmembrane transport
C0092_13305	COG5002	protein histidine kinase activity
C0092_13315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0092_13360	COG1301	dicarboxylic acid transport
C0092_13365	COG1530	ribonuclease E activity
C0092_13380	COG0285	dihydrofolate synthase activity
C0092_13390	COG3268	Saccharopine dehydrogenase
C0092_13395	COG1388	LysM domain
C0092_13415	COG1013	pyruvate-flavodoxin oxidoreductase activity
C0092_13420	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C0092_13420	COG0674	pyruvate-flavodoxin oxidoreductase activity
C0092_13435	COG2040	homocysteine
C0092_13455	COG0544	peptidyl-prolyl cis-trans isomerase activity
C0092_13470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0092_13485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C0092_13515	COG0366	Alpha amylase catalytic
C0092_13535	COG0824	Thioesterase
C0092_13540	COG2902	Dehydrogenase
C0092_13605	COG0657	acetylesterase activity
C0092_13645	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
C0092_13650	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0092_13670	COG2030	dehydratase
C0092_13675	COG1960	acyl-CoA dehydrogenase activity
C0092_13685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0092_13700	COG0318	PFAM AMP-dependent synthetase and ligase
C0092_13720	COG0300	oxidoreductase activity
C0092_13725	COG0433	COG0433 Predicted ATPase
C0092_13840	COG3757	hydrolase, family 25
C0092_13860	COG1715	Restriction endonuclease
C0092_13890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0092_13960	COG1487	ribonuclease activity
C0092_14005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C0092_14015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C0092_14020	COG0432	Pfam Uncharacterised protein family UPF0047
C0092_14070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0092_14070	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0092_14140	COG0596	Alpha beta hydrolase
C0092_14175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0092_14200	COG1022	Amp-dependent synthetase and ligase
C0092_14200	COG3320	Male sterility
C0092_14280	COG1946	Acyl-CoA thioesterase
C0092_14295	COG5651	PPE family
C0092_14335	COG3391	amine dehydrogenase activity
C0092_14340	COG4762	Protein conserved in bacteria
C0092_14475	COG0640	Transcriptional regulator
C0092_14480	COG0798	PFAM Bile acid sodium symporter
C0092_14490	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0092_14520	COG4974	Belongs to the 'phage' integrase family
C0092_14670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C0092_14725	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C0092_14760	COG0531	amino acid
C0092_14765	COG0569	domain protein
C0092_14910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C0092_14930	COG1960	acyl-CoA dehydrogenase activity
C0092_14935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C0092_14965	COG1196	nuclear chromosome segregation
C0092_15020	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
C0092_15030	COG3391	amine dehydrogenase activity
C0092_15060	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C0092_15105	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C0092_15160	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_15200	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C0092_15230	COG1522	sequence-specific DNA binding
C0092_15235	COG0686	Belongs to the AlaDH PNT family
C0092_15245	COG0612	Peptidase, M16
C0092_15280	COG1960	acyl-CoA dehydrogenase activity
C0092_15285	COG0183	Belongs to the thiolase family
C0092_15340	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0092_15345	COG3609	addiction module antidote protein, CC2985 family
C0092_15450	COG1353	crispr-associated protein
C0092_15485	COG3744	PilT protein domain protein
C0092_15490	COG4118	positive regulation of growth
C0092_15505	COG1653	transport
C0092_15510	COG0395	ABC-type sugar transport system, permease component
C0092_15525	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C0092_15575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0092_15575	COG1648	precorrin-2 dehydrogenase activity
C0092_15620	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
C0092_15645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C0092_15680	COG2161	toxin-antitoxin pair type II binding
C0092_15685	COG2026	Addiction module toxin, RelE StbE family
C0092_15780	COG0745	RESPONSE REGULATOR receiver
C0092_15805	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C0092_15845	COG0606	chelatase, subunit chli
C0092_15915	COG1686	Belongs to the peptidase S11 family
C0092_15950	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C0092_16115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0092_16115	COG3321	synthase
C0092_16115	COG4221	oxidoreductase activity
C0092_16115	COG0604	alcohol dehydrogenase
C0092_16120	COG3321	synthase
C0092_16135	COG0318	PFAM AMP-dependent synthetase and ligase
C0092_16185	COG1819	glycosyl
C0092_16210	COG0701	Predicted permease
C0092_16235	COG0742	ribosomal rna small subunit methyltransferase
C0092_16245	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C0092_16265	COG0656	L-ascorbic acid biosynthetic process
C0092_16285	COG1461	Dihydroxyacetone kinase
C0092_16365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C0092_16400	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0092_16410	COG0473	3-isopropylmalate dehydrogenase activity
C0092_16435	COG2972	Histidine kinase
C0092_16445	COG0390	transport system, permease component
C0092_16470	COG2259	Doxx family
C0092_16500	COG0154	amidase activity
C0092_16630	COG0110	maltose O-acetyltransferase activity
C0092_16635	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0092_16665	COG1119	ATPase activity
C0092_16670	COG0560	Phosphoserine phosphatase
C0092_16670	COG3830	Belongs to the UPF0237 family
C0092_16715	COG1309	transcriptional regulator
C0092_16775	COG2186	Transcriptional regulator
C0092_16780	COG1960	acyl-CoA dehydrogenase activity
C0092_16875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0092_16950	COG2354	Protein conserved in bacteria
C0092_16965	COG1733	regulation of RNA biosynthetic process
C0092_16975	COG0657	acetylesterase activity
C0092_16985	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0092_17005	COG2177	Part of the ABC transporter FtsEX involved in
C0092_17010	COG2884	Cell division ATP-binding protein ftsE
C0092_17020	COG0668	transmembrane transport
C0092_17035	COG0277	FAD linked oxidase domain protein
C0092_17050	COG2154	pterin-4-alpha-carbinolamine dehydratase
C0092_17060	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C0092_17130	COG3629	intracellular signal transduction
C0092_17155	COG2801	Transposase and inactivated derivatives
C0092_17165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0092_17215	COG0483	inositol monophosphate 1-phosphatase activity
C0092_17230	COG1960	acyl-CoA dehydrogenase activity
C0092_17295	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0092_17350	COG0714	Associated with various cellular activities
C0092_17395	COG1309	transcriptional regulator
C0092_17405	COG0154	amidase activity
C0092_17420	COG0748	coenzyme F420 binding
C0092_17450	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
C0092_17455	COG1396	sequence-specific DNA binding
C0092_17495	COG2826	transposase and inactivated derivatives, IS30 family
C0092_17545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C0092_17565	COG2816	NAD+ diphosphatase activity
C0092_17575	COG0210	DNA helicase
C0092_17590	COG0596	Alpha beta hydrolase
C0092_17595	COG3695	enzyme binding
C0092_17635	COG0513	Belongs to the DEAD box helicase family
C0092_17650	COG0406	alpha-ribazole phosphatase activity
C0092_17670	COG1597	lipid kinase activity
C0092_17710	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_17720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0092_17730	COG2135	peptidase activity
C0092_17740	COG1162	GTPase activity
C0092_17760	COG2326	polyphosphate kinase activity
C0092_17775	COG4651	solute:proton antiporter activity
C0092_17775	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C0092_17785	COG2020	methyltransferase activity
C0092_17800	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C0092_17855	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0092_17860	COG0531	amino acid
C0092_17865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0092_17870	COG1482	cell wall glycoprotein biosynthetic process
C0092_17880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0092_17940	COG1316	TRANSCRIPTIONal
C0092_17965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C0092_17970	COG0659	secondary active sulfate transmembrane transporter activity
C0092_18005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0092_18015	COG0424	maF-like protein
C0092_18030	COG4770	biotin carboxylase activity
C0092_18060	COG1522	sequence-specific DNA binding
C0092_18070	COG1012	belongs to the aldehyde dehydrogenase family
C0092_18080	COG1309	transcriptional regulator
C0092_18085	COG1201	RNA secondary structure unwinding
C0092_18105	COG0564	pseudouridine synthase activity
C0092_18130	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
C0092_18130	COG1473	amidohydrolase
C0092_18145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0092_18155	COG3511	phospholipase C
C0092_18195	COG2009	succinate dehydrogenase
C0092_18205	COG1053	succinate dehydrogenase
C0092_18210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C0092_18255	COG1595	DNA-templated transcription, initiation
C0092_18260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C0092_18265	COG1686	Belongs to the peptidase S11 family
C0092_18270	COG2814	Major facilitator Superfamily
C0092_18275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C0092_18290	COG0789	Transcriptional regulator
C0092_18295	COG1295	ribonuclease BN
C0092_18315	COG2873	o-acetylhomoserine
C0092_18330	COG5651	PPE family
C0092_18345	COG5651	PPE family
C0092_18345	COG5651	PPE family
C0092_18375	COG5651	PPE family
C0092_18375	COG5651	PPE family
C0092_18375	COG5651	PPE family
C0092_18385	COG0277	FAD linked oxidase domain protein
C0092_18410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C0092_18425	COG1902	pentaerythritol trinitrate reductase activity
C0092_18425	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0092_18430	COG1716	ATPase activity
C0092_18430	COG1131	(ABC) transporter
C0092_18430	COG0842	Transport permease protein
C0092_18435	COG1357	PFAM Pentapeptide repeats (8 copies)
C0092_18450	COG2018	Roadblock/LC7 domain
C0092_18460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C0092_18485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0092_18500	COG1024	Enoyl-CoA hydratase
C0092_18520	COG1657	PFAM Prenyltransferase squalene oxidase
C0092_18530	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C0092_18535	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C0092_18555	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
C0092_18585	COG0406	alpha-ribazole phosphatase activity
C0092_18595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0092_18745	COG0456	acetyltransferase
C0092_18775	COG5651	PPE family
C0092_18790	COG1484	DNA-dependent DNA replication
C0092_18795	COG4584	PFAM Integrase catalytic
C0092_18825	COG0076	glutamate decarboxylase activity
C0092_18910	COG1404	Belongs to the peptidase S8 family
C0092_18960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C0092_19000	COG1403	HNH endonuclease
C0092_19005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C0092_19010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0092_19015	COG0028	Belongs to the TPP enzyme family
C0092_19040	COG0477	Major facilitator Superfamily
C0092_19050	COG5651	PPE family
C0092_19055	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0092_19060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0092_19080	COG1316	TRANSCRIPTIONal
C0092_19085	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_19095	COG2259	Doxx family
C0092_19100	COG0657	acetylesterase activity
C0092_19105	COG1695	Transcriptional regulator
C0092_19115	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C0092_19140	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0092_19165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0092_19170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0092_19185	COG1960	acyl-CoA dehydrogenase activity
C0092_19190	COG1960	acyl-CoA dehydrogenase activity
C0092_19200	COG0657	acetylesterase activity
C0092_19205	COG0657	acetylesterase activity
C0092_19210	COG0028	Belongs to the TPP enzyme family
C0092_19220	COG0657	acetylesterase activity
C0092_19230	COG0657	acetylesterase activity
C0092_19245	COG1024	Enoyl-CoA hydratase
C0092_19255	COG2124	cytochrome p450
C0092_19265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0092_19275	COG0183	Belongs to the thiolase family
C0092_19295	COG4638	Rieske (2fe-2S)
C0092_19325	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_19385	COG2030	dehydratase
C0092_19390	COG1960	acyl-CoA dehydrogenase activity
C0092_19395	COG1960	acyl-CoA dehydrogenase activity
C0092_19405	COG0183	Belongs to the thiolase family
C0092_19415	COG1028	Short-chain dehydrogenase reductase Sdr
C0092_19430	COG1024	Enoyl-CoA hydratase
C0092_19450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0092_19460	COG0183	Belongs to the thiolase family
C0092_19480	COG1960	acyl-CoA dehydrogenase activity
C0092_19485	COG0318	PFAM AMP-dependent synthetase and ligase
C0092_19490	COG1960	acyl-CoA dehydrogenase activity
C0092_19495	COG1960	acyl-CoA dehydrogenase activity
C0092_19500	COG1960	acyl-CoA dehydrogenase activity
C0092_19505	COG0436	Aminotransferase
C0092_19555	COG1960	acyl-CoA dehydrogenase activity
C0092_19560	COG1309	transcriptional regulator
C0092_19565	COG1609	Transcriptional regulator
C0092_19620	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C0092_19640	COG0657	acetylesterase activity
C0092_19660	COG0739	heme binding
C0092_19670	COG0542	response to heat
C0092_19780	COG2267	carboxylic ester hydrolase activity
C0092_19830	COG2027	D-alanyl-D-alanine carboxypeptidase
C0092_19895	COG2184	nucleotidyltransferase activity
C0092_19915	COG0470	DNA polymerase III
C0092_19940	COG1111	helicase
C0092_19940	COG1205	dead DEAH box helicase
C0092_19945	COG0657	acetylesterase activity
C0092_19965	COG0657	acetylesterase activity
C0092_20025	COG4172	Belongs to the ABC transporter superfamily
C0092_20035	COG0601	transmembrane transport
C0092_20075	COG0494	nUDIX hydrolase
C0092_20100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0092_20135	COG1408	metallophosphoesterase
C0092_20140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0092_20190	COG0714	Associated with various cellular activities
C0092_20215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C0092_20250	COG0121	glutamine amidotransferase
C0092_20305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C0092_20330	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0092_20345	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0092_20355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0092_20385	COG1063	alcohol dehydrogenase
C0092_20390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0092_20390	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C0092_20395	COG0477	Major facilitator Superfamily
C0092_20400	COG2226	methyltransferase
C0092_20410	COG1793	dna ligase
C0092_20460	COG2072	flavoprotein involved in K transport
C0092_20470	COG0640	Transcriptional regulator
C0092_20495	COG1569	PIN domain
C0092_20500	COG3311	Transcriptional regulator
C0092_20520	COG0590	tRNA wobble adenosine to inosine editing
C0092_20530	COG0287	Prephenate dehydrogenase
C0092_20550	COG0517	IMP dehydrogenase activity
C0092_20550	COG1125	glycine betaine transport
C0092_20560	COG5416	Lipopolysaccharide assembly protein A domain
C0092_20570	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C0092_20580	COG2205	protein histidine kinase activity
C0092_20585	COG0745	RESPONSE REGULATOR receiver
C0092_20590	COG0739	heme binding
C0092_20635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C0092_20700	COG1088	dTDP-glucose 4,6-dehydratase activity
C0092_20710	COG0739	heme binding
C0092_20710	COG1216	Glycosyl transferase, family 2
C0092_20760	COG1234	tRNA 3'-trailer cleavage
C0092_20765	COG1960	acyl-CoA dehydrogenase activity
C0092_20775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0092_20785	COG0318	PFAM AMP-dependent synthetase and ligase
C0092_20805	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C0092_20820	COG1216	Glycosyl transferase, family 2
C0092_20840	COG3391	amine dehydrogenase activity
C0092_20855	COG0561	phosphatase activity
C0092_20890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0092_20900	COG5651	PPE family
C0092_20905	COG1511	domain protein
C0092_20905	COG2409	Drug exporters of the RND superfamily
C0092_20960	COG2207	Transcriptional regulator
C0092_21000	COG1316	TRANSCRIPTIONal
C0092_21070	COG2119	membrane
C0092_21110	COG1796	DNA polymerase
C0092_21110	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C0092_21125	COG0070	glutamate synthase
C0092_21125	COG0069	glutamate synthase activity
C0092_21125	COG0067	glutamate synthase
C0092_21235	COG4932	domain protein
C0092_21255	COG1404	Belongs to the peptidase S8 family
C0092_21300	COG5651	PPE family
C0092_21310	COG1674	ftsk spoiiie
C0092_21420	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0092_21420	COG3409	Peptidoglycan-binding domain 1 protein
C0092_21440	COG1192	Involved in chromosome partitioning