locus-tag	class	description
Rv0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Rv0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Rv0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Rv0018c	COG0631	protein serine/threonine phosphatase activity
Rv0018c	COG3266	domain, Protein
Rv0020c	COG1716	ATPase activity
Rv0033	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Rv0037c	COG2814	Major facilitator Superfamily
Rv0044c	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Rv0046c	COG1260	myo-inositol-1-phosphate synthase
Rv0050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Rv0058	COG1372	Participates in initiation and elongation during chromosome replication
Rv0058	COG0305	Participates in initiation and elongation during chromosome replication
Rv0063	COG0277	FAD linked oxidase domain protein
Rv0064	COG1615	UPF0182 protein
Rv0067c	COG1309	transcriptional regulator
Rv0068	COG1028	Short-chain dehydrogenase reductase Sdr
Rv0071	COG3344	reverse transcriptase
Rv0074	COG1228	amidohydrolase
Rv0078	COG1309	transcriptional regulator
Rv0082	COG3260	NADH ubiquinone oxidoreductase 20
Rv0084	COG0650	Formate hydrogenlyase subunit 4
Rv0086	COG0651	ATP synthesis coupled electron transport
Rv0087	COG3261	NADH dehydrogenase
Rv0087	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Rv0088	COG3832	glyoxalase III activity
Rv0094c	COG1403	HNH endonuclease
Rv0095c	COG1403	HNH endonuclease
Rv0101	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Rv0103c	COG2217	Heavy metal translocating P-type atpase
Rv0107c	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Rv0109	COG0657	acetylesterase activity
Rv0111	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Rv0111	COG2755	lipolytic protein G-D-S-L family
Rv0117	COG0583	DNA-binding transcription factor activity
Rv0118c	COG0028	Belongs to the TPP enzyme family
Rv0120c	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Rv0125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Rv0127	COG3281	Trehalose synthase
Rv0132c	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Rv0134	COG0596	Alpha beta hydrolase
Rv0143c	COG0038	chloride channel
Rv0144	COG1309	transcriptional regulator
Rv0147	COG1012	belongs to the aldehyde dehydrogenase family
Rv0148	COG1028	Short-chain dehydrogenase reductase Sdr
Rv0149	COG3321	synthase
Rv0149	COG1028	Short-chain dehydrogenase reductase Sdr
Rv0149	COG0604	alcohol dehydrogenase
Rv0153c	COG2365	Tyrosine phosphatase family
Rv0155	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Rv0157	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Rv0158	COG1309	transcriptional regulator
Rv0159c	COG0657	acetylesterase activity
Rv0159c	COG5651	PPE family
Rv0160c	COG5651	PPE family
Rv0160c	COG0657	acetylesterase activity
Rv0161	COG0277	FAD linked oxidase domain protein
Rv0162c	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Rv0165c	COG1802	Transcriptional regulator
Rv0167	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Rv0168	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Rv0173	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Rv0183	COG2267	carboxylic ester hydrolase activity
Rv0186	COG1472	Belongs to the glycosyl hydrolase 3 family
Rv0190	COG1937	Protein conserved in bacteria
Rv0192	COG1376	ErfK ybiS ycfS ynhG family protein
Rv0194	COG1132	(ABC) transporter
Rv0197	COG0243	molybdopterin cofactor binding
Rv0198c	COG3590	peptidase
Rv0206c	COG2409	Drug exporters of the RND superfamily
Rv0218	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Rv0222	COG1024	Enoyl-CoA hydratase
Rv0225	COG0297	glycogen (starch) synthase activity
Rv0229c	COG1487	ribonuclease activity
Rv0233	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Rv0236c	COG4981	capsule polysaccharide biosynthetic process
Rv0237	COG1472	Belongs to the glycosyl hydrolase 3 family
Rv0243	COG0183	Belongs to the thiolase family
Rv0244c	COG1960	acyl-CoA dehydrogenase activity
Rv0248c	COG1053	succinate dehydrogenase
Rv0252	COG2146	nitrite reductase [NAD(P)H] activity
Rv0252	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Rv0256c	COG5651	PPE family
Rv0263c	COG1984	allophanate hydrolase subunit 2
Rv0267	COG2223	nitrite transmembrane transporter activity
Rv0268c	COG2161	toxin-antitoxin pair type II binding
Rv0270	COG0318	PFAM AMP-dependent synthetase and ligase
Rv0271c	COG1960	acyl-CoA dehydrogenase activity
Rv0274	COG0346	lactoylglutathione lyase activity
Rv0278c	COG3391	amine dehydrogenase activity
Rv0280	COG5651	PPE family
Rv0284	COG1674	ftsk spoiiie
Rv0284	COG1672	PFAM Archaeal ATPase
Rv0291	COG1404	Belongs to the peptidase S8 family
Rv0296c	COG1368	sulfuric ester hydrolase activity
Rv0297	COG3391	amine dehydrogenase activity
Rv0306	COG0778	Nitroreductase
Rv0308	COG0671	phosphoesterase, PA-phosphatase related
Rv0321	COG0717	Belongs to the dCTP deaminase family
Rv0322	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Rv0323c	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Rv0326	COG2226	methyltransferase
Rv0329c	COG2226	methyltransferase
Rv0331	COG1252	NADH dehydrogenase
Rv0338c	COG0247	lactate metabolic process
Rv0338c	COG2181	nitrate reductase activity
Rv0353	COG0789	Transcriptional regulator
Rv0355c	COG5651	PPE family
Rv0355c	COG5263	repeat protein
Rv0359	COG1994	Peptidase M50
Rv0362	COG2239	Acts as a magnesium transporter
Rv0371c	COG0746	molybdenum cofactor guanylyltransferase activity
Rv0379	COG3360	Dodecin
Rv0389	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Rv0392c	COG1252	NADH dehydrogenase
Rv0393	COG1403	HNH endonuclease
Rv0400c	COG1960	acyl-CoA dehydrogenase activity
Rv0405	COG3321	synthase
Rv0405	COG0604	alcohol dehydrogenase
Rv0406c	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Rv0411c	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Rv0417	COG2022	thiamine diphosphate biosynthetic process
Rv0418	COG2234	aminopeptidase activity
Rv0425c	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Rv0435c	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Rv0436c	COG1183	phosphatidylcholine synthase activity
Rv0439c	COG1028	Short-chain dehydrogenase reductase Sdr
Rv0440	COG0459	protein refolding
Rv0444c	COG5343	regulation of RNA biosynthetic process
Rv0447c	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Rv0456A	COG2337	Toxic component of a toxin-antitoxin (TA) module
Rv0456c	COG1024	Enoyl-CoA hydratase
Rv0457c	COG1505	serine-type exopeptidase activity
Rv0469	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Rv0473	COG2733	membrane
Rv0505c	COG0560	Phosphoserine phosphatase
Rv0507	COG2409	Drug exporters of the RND superfamily
Rv0507	COG1033	growth of symbiont in host cell
Rv0511	COG1648	precorrin-2 dehydrogenase activity
Rv0511	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Rv0517	COG2755	lipolytic protein G-D-S-L family
Rv0517	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Rv0522	COG1113	amino acid transport
Rv0525	COG0406	alpha-ribazole phosphatase activity
Rv0527	COG0785	Cytochrome C biogenesis protein
Rv0529	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Rv0532	COG3391	amine dehydrogenase activity
Rv0535	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Rv0536	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Rv0545c	COG0306	phosphate transporter
Rv0547c	COG4221	oxidoreductase activity
Rv0551c	COG0318	PFAM AMP-dependent synthetase and ligase
Rv0552	COG1228	amidohydrolase
Rv0565c	COG2072	flavoprotein involved in K transport
Rv0567	COG2345	Transcriptional regulator
Rv0570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Rv0582	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
Rv0584	COG3537	Alpha-1,2-mannosidase
Rv0588	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Rv0593	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Rv0595c	COG1487	ribonuclease activity
Rv0599c	COG2002	toxin-antitoxin pair type II binding
Rv0601c	COG2972	Histidine kinase
Rv0602c	COG0745	RESPONSE REGULATOR receiver
Rv0613c	COG0653	protein targeting
Rv0620	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Rv0627	COG1487	ribonuclease activity
Rv0631c	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Rv0636	COG2030	dehydratase
Rv0641	COG0081	regulation of translation
Rv0642c	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Rv0644c	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Rv0672	COG1960	acyl-CoA dehydrogenase activity
Rv0675	COG1024	Enoyl-CoA hydratase
Rv0676c	COG2409	Drug exporters of the RND superfamily
Rv0676c	COG1033	growth of symbiont in host cell
Rv0678	COG1510	regulation of RNA biosynthetic process
Rv0692	COG0535	radical SAM domain protein
Rv0712	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Rv0723	COG0200	Binds to the 23S rRNA
Rv0724	COG0616	signal peptide processing
Rv0724A	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Rv0725c	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Rv0726c	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Rv0727c	COG0235	Class ii aldolase
Rv0728c	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Rv0731c	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Rv0742	COG0657	acetylesterase activity
Rv0754	COG0406	alpha-ribazole phosphatase activity
Rv0757	COG0745	RESPONSE REGULATOR receiver
Rv0758	COG2205	protein histidine kinase activity
Rv0765c	COG1028	Short-chain dehydrogenase reductase Sdr
Rv0777	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Rv0783c	COG0477	Major facilitator Superfamily
Rv0785	COG3573	Dehydrogenase
Rv0787A	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Rv0791c	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Rv0792c	COG2188	Transcriptional regulator
Rv0793	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Rv0794c	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Rv0799c	COG2837	iron assimilation
Rv0800	COG1362	aminopeptidase activity
Rv0809	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Rv0818	COG0745	RESPONSE REGULATOR receiver
Rv0827c	COG0640	Transcriptional regulator
Rv0828c	COG0590	tRNA wobble adenosine to inosine editing
Rv0830	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Rv0832	COG3391	amine dehydrogenase activity
Rv0839	COG4106	trans-aconitate 2-methyltransferase activity
Rv0840c	COG0596	Alpha beta hydrolase
Rv0843	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Rv0845	COG4585	Histidine kinase
Rv0846c	COG2132	Multicopper oxidase
Rv0848	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Rv0859	COG0183	Belongs to the thiolase family
Rv0860	COG1024	Enoyl-CoA hydratase
Rv0860	COG1250	3-hydroxyacyl-CoA dehydrogenase
Rv0865	COG0521	Mo-molybdopterin cofactor biosynthetic process
Rv0870c	COG3304	Inner membrane component domain
Rv0871	COG1278	Cold shock
Rv0881	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Rv0885	COG3396	Phenylacetate-CoA oxygenase
Rv0890c	COG3903	Transcriptional regulator
Rv0890c	COG2197	response regulator
Rv0891c	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Rv0914c	COG0183	Belongs to the thiolase family
Rv0920c	COG3328	transposase activity
Rv0930	COG0581	inorganic phosphate transmembrane transporter activity
Rv0938	COG1793	dna ligase
Rv0938	COG3285	dna ligase
Rv0944	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Rv0950c	COG0739	heme binding
Rv0951	COG0045	succinate-CoA ligase (ADP-forming) activity
Rv0959	COG4867	von Willebrand factor, type A
Rv0966c	COG4758	membrane
Rv0971c	COG1024	Enoyl-CoA hydratase
Rv0974c	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Rv0977	COG0657	acetylesterase activity
Rv0978c	COG3391	amine dehydrogenase activity
Rv0980c	COG3391	amine dehydrogenase activity
Rv0981	COG0745	RESPONSE REGULATOR receiver
Rv0982	COG2205	protein histidine kinase activity
Rv0982	COG2972	Histidine kinase
Rv0983	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Rv0984	COG0521	Mo-molybdopterin cofactor biosynthetic process
Rv0984	COG0315	cyclic pyranopterin monophosphate synthase activity
Rv0992c	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Rv0993	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Rv0998	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Rv0998	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Rv1005c	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Rv1007c	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Rv1008	COG0084	hydrolase, TatD family'
Rv1013	COG0318	PFAM AMP-dependent synthetase and ligase
Rv1019	COG1309	transcriptional regulator
Rv1021	COG3956	TIGRFAM MazG family protein
Rv1023	COG4948	Mandelate Racemase Muconate Lactonizing
Rv1028c	COG2205	protein histidine kinase activity
Rv1032c	COG2205	protein histidine kinase activity
Rv1033c	COG0745	RESPONSE REGULATOR receiver
Rv1040c	COG0657	acetylesterase activity
Rv1043c	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Rv1050	COG1028	Short-chain dehydrogenase reductase Sdr
Rv1058	COG0318	PFAM AMP-dependent synthetase and ligase
Rv1074c	COG0183	Belongs to the thiolase family
Rv1076	COG0657	acetylesterase activity
Rv1084	COG1331	Highly conserved protein containing a thioredoxin domain
Rv1088	COG0657	acetylesterase activity
Rv1093	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Rv1095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Rv1104	COG2272	Belongs to the type-B carboxylesterase lipase family
Rv1112	COG0012	GTP binding
Rv1122	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Rv1124	COG0596	Alpha beta hydrolase
Rv1127c	COG0574	Belongs to the PEP-utilizing enzyme family
Rv1127c	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Rv1128c	COG1403	HNH endonuclease
Rv1129c	COG1396	sequence-specific DNA binding
Rv1129c	COG3800	Transcriptional regulator
Rv1130	COG2079	MmgE PrpD family protein
Rv1135A	COG0183	Belongs to the thiolase family
Rv1139c	COG1755	Isoprenylcysteine carboxyl methyltransferase
Rv1141c	COG1024	Enoyl-CoA hydratase
Rv1142c	COG1024	Enoyl-CoA hydratase
Rv1143	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Rv1145	COG2409	Drug exporters of the RND superfamily
Rv1146	COG2409	Drug exporters of the RND superfamily
Rv1148c	COG1403	HNH endonuclease
Rv1153c	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Rv1155	COG3467	pyridoxamine 5'-phosphate
Rv1162	COG1140	nitrate reductase beta subunit
Rv1175c	COG1902	pentaerythritol trinitrate reductase activity
Rv1175c	COG0446	pyridine nucleotide-disulphide oxidoreductase
Rv1177	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Rv1180	COG3321	synthase
Rv1180	COG0604	alcohol dehydrogenase
Rv1180	COG1028	Short-chain dehydrogenase reductase Sdr
Rv1181	COG0604	alcohol dehydrogenase
Rv1181	COG3321	synthase
Rv1181	COG1028	Short-chain dehydrogenase reductase Sdr
Rv1184c	COG5651	PPE family
Rv1186c	COG2508	Transcriptional regulator
Rv1186c	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Rv1187	COG1012	belongs to the aldehyde dehydrogenase family
Rv1188	COG0506	proline dehydrogenase activity
Rv1190	COG0596	Alpha beta hydrolase
Rv1193	COG0318	PFAM AMP-dependent synthetase and ligase
Rv1195	COG0657	acetylesterase activity
Rv1196	COG5651	PPE family
Rv1197	COG4842	Belongs to the WXG100 family
Rv1200	COG0477	Major facilitator Superfamily
Rv1205	COG1611	Belongs to the LOG family
Rv1210	COG0519	Catalyzes the synthesis of GMP from XMP
Rv1217c	COG3559	Exporter of polyketide antibiotics
Rv1218c	COG1131	(ABC) transporter
Rv1219c	COG1309	transcriptional regulator
Rv1222	COG5662	AntiSigma factor
Rv1223	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Rv1224	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Rv1232c	COG2239	Acts as a magnesium transporter
Rv1239c	COG0598	Magnesium transport protein CorA
Rv1246c	COG2026	Addiction module toxin, RelE StbE family
Rv1247c	COG2161	toxin-antitoxin pair type II binding
Rv1248c	COG0567	Dehydrogenase, E1 component
Rv1248c	COG0508	dehydrogenase complex catalyzes the overall conversion of
Rv1257c	COG0277	FAD linked oxidase domain protein
Rv1266c	COG0515	serine threonine protein kinase
Rv1273c	COG1132	(ABC) transporter
Rv1290c	COG4325	translation initiation factor activity
Rv1300	COG2890	protein-(glutamine-N5) methyltransferase activity
Rv1319c	COG2972	Histidine kinase
Rv1319c	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Rv1320c	COG2972	Histidine kinase
Rv1320c	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Rv1321	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
Rv1326c	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Rv1328	COG0058	SHG alpha-glucan phosphorylase activity
Rv1330c	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Rv1361c	COG5651	PPE family
Rv1377c	COG2226	methyltransferase
Rv1392	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Rv1393c	COG2072	flavoprotein involved in K transport
Rv1394c	COG2124	cytochrome p450
Rv1426c	COG2272	Belongs to the type-B carboxylesterase lipase family
Rv1427c	COG0318	PFAM AMP-dependent synthetase and ligase
Rv1433	COG1376	ErfK ybiS ycfS ynhG family protein
Rv1441c	COG0657	acetylesterase activity
Rv1448c	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Rv1449c	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Rv1450c	COG0657	acetylesterase activity
Rv1451	COG0109	protoheme IX farnesyltransferase activity
Rv1452c	COG0657	acetylesterase activity
Rv1458c	COG1131	(ABC) transporter
Rv1462	COG0719	Fe-S assembly protein
Rv1463	COG0396	ATPase activity
Rv1466	COG2151	metal-sulfur cluster biosynthetic enzyme
Rv1467c	COG1960	acyl-CoA dehydrogenase activity
Rv1471	COG3118	belongs to the thioredoxin family
Rv1473	COG0488	(ABC) transporter
Rv1474c	COG1309	transcriptional regulator
Rv1475c	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Rv1477	COG3883	PFAM NLP P60 protein
Rv1477	COG0791	NLP P60 protein
Rv1479	COG0714	Associated with various cellular activities
Rv1498A	COG3360	Dodecin
Rv1498c	COG2226	methyltransferase
Rv1502	COG1621	beta-fructofuranosidase activity
Rv1503c	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Rv1504c	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Rv1506c	COG4106	trans-aconitate 2-methyltransferase activity
Rv1508A	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Rv1511	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Rv1512	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Rv1527c	COG3321	synthase
Rv1527c	COG1028	Short-chain dehydrogenase reductase Sdr
Rv1527c	COG0604	alcohol dehydrogenase
Rv1533	COG2070	2-Nitropropane dioxygenase
Rv1544	COG0300	oxidoreductase activity
Rv1549	COG1022	Amp-dependent synthetase and ligase
Rv1554	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
Rv1566c	COG3883	PFAM NLP P60 protein
Rv1566c	COG0791	NLP P60 protein
Rv1570	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Rv1587c	COG1403	HNH endonuclease
Rv1588c	COG1403	HNH endonuclease
Rv1592c	COG1073	alpha beta
Rv1602	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Rv1604	COG0483	inositol monophosphate 1-phosphatase activity
Rv1605	COG0107	imidazoleglycerol-phosphate synthase activity
Rv1607	COG0387	Pfam Sodium calcium exchanger
Rv1618	COG1946	Acyl-CoA thioesterase
Rv1619	COG0456	acetyltransferase
Rv1619	COG0454	-acetyltransferase
Rv1620c	COG4988	ABC transporter
Rv1621c	COG4988	ABC transporter
Rv1622c	COG1294	oxidase, subunit
Rv1623c	COG1271	oxidase subunit
Rv1637c	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Rv1646	COG0657	acetylesterase activity
Rv1649	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Rv1651c	COG3391	amine dehydrogenase activity
Rv1661	COG0604	alcohol dehydrogenase
Rv1661	COG3321	synthase
Rv1662	COG0604	alcohol dehydrogenase
Rv1662	COG3321	synthase
Rv1663	COG4221	oxidoreductase activity
Rv1663	COG3321	synthase
Rv1663	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Rv1663	COG0604	alcohol dehydrogenase
Rv1664	COG0604	alcohol dehydrogenase
Rv1664	COG3321	synthase
Rv1664	COG0604	alcohol dehydrogenase
Rv1664	COG3321	synthase
Rv1667c	COG0488	(ABC) transporter
Rv1668c	COG0488	(ABC) transporter
Rv1679	COG1960	acyl-CoA dehydrogenase activity
Rv1680	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Rv1684	COG2835	tetraacyldisaccharide 4'-kinase activity
Rv1692	COG0647	UMP catabolic process
Rv1700	COG0494	nUDIX hydrolase
Rv1704c	COG1113	amino acid transport
Rv1705c	COG5651	PPE family
Rv1707	COG0659	secondary active sulfate transmembrane transporter activity
Rv1710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Rv1718	COG3246	L-lysine catabolic process to acetate
Rv1725c	COG1733	regulation of RNA biosynthetic process
Rv1729c	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Rv1739c	COG0659	secondary active sulfate transmembrane transporter activity
Rv1745c	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Rv1747	COG1716	ATPase activity
Rv1747	COG1131	(ABC) transporter
Rv1747	COG0842	Transport permease protein
Rv1750c	COG0318	PFAM AMP-dependent synthetase and ligase
Rv1753c	COG5263	repeat protein
Rv1753c	COG5651	PPE family
Rv1760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Rv1766	COG1937	Protein conserved in bacteria
Rv1787	COG5651	PPE family
Rv1789	COG5651	PPE family
Rv1790	COG5651	PPE family
Rv1796	COG1404	Belongs to the peptidase S8 family
Rv1800	COG5651	PPE family
Rv1803c	COG0657	acetylesterase activity
Rv1806	COG0657	acetylesterase activity
Rv1809	COG5651	PPE family
Rv1811	COG1285	pathogenesis
Rv1812c	COG1252	NADH dehydrogenase
Rv1826	COG0509	glycine decarboxylation via glycine cleavage system
Rv1832	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Rv1832	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Rv1841c	COG1253	flavin adenine dinucleotide binding
Rv1842c	COG1253	flavin adenine dinucleotide binding
Rv1844c	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Rv1851	COG0830	nickel cation binding
Rv1855c	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Rv1865c	COG4221	oxidoreductase activity
Rv1866	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Rv1867	COG0183	Belongs to the thiolase family
Rv1878	COG0174	glutamine synthetase
Rv1882c	COG0300	oxidoreductase activity
Rv1884c	COG1652	LysM domain
Rv1888A	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Rv1889c	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Rv1894c	COG2070	2-Nitropropane dioxygenase
Rv1895	COG1063	alcohol dehydrogenase
Rv1896c	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Rv1899c	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Rv1903	COG1950	PFAM Membrane protein of
Rv1908c	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Rv1915	COG2224	Isocitrate lyase
Rv1917c	COG5263	repeat protein
Rv1917c	COG5651	PPE family
Rv1918c	COG5651	PPE family
Rv1918c	COG5263	repeat protein
Rv1922	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Rv1928c	COG1028	Short-chain dehydrogenase reductase Sdr
Rv1931c	COG4977	sequence-specific DNA binding
Rv1933c	COG1960	acyl-CoA dehydrogenase activity
Rv1934c	COG1960	acyl-CoA dehydrogenase activity
Rv1935c	COG1024	Enoyl-CoA hydratase
Rv1937	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Rv1937	COG0543	2 iron, 2 sulfur cluster binding
Rv1940	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Rv1940	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Rv1941	COG1028	Short-chain dehydrogenase reductase Sdr
Rv1942c	COG2337	Toxic component of a toxin-antitoxin (TA) module
Rv1944c	COG0653	protein targeting
Rv1952	COG4691	Plasmid stability protein
Rv1963c	COG1309	transcriptional regulator
Rv1970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Rv1990A	COG1028	Short-chain dehydrogenase reductase Sdr
Rv1996	COG0589	response to stress
Rv2018	COG2442	InterPro IPR007367
Rv2021c	COG1396	sequence-specific DNA binding
Rv2022c	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
Rv2034	COG0640	Transcriptional regulator
Rv2037c	COG1752	Esterase of the alpha-beta hydrolase superfamily
Rv2038c	COG3842	ATPase activity
Rv2039c	COG0395	ABC-type sugar transport system, permease component
Rv2040c	COG1175	transmembrane transport
Rv2043c	COG1335	isochorismatase
Rv2054	COG0412	Dienelactone hydrolase
Rv2059	COG0803	Belongs to the bacterial solute-binding protein 9 family
Rv2063A	COG2337	Toxic component of a toxin-antitoxin (TA) module
Rv2067c	COG0500	methyltransferase
Rv2072c	COG2241	protein methyltransferase activity
Rv2072c	COG2242	protein methyltransferase activity
Rv2073c	COG0300	oxidoreductase activity
Rv2079	COG1511	domain protein
Rv2086	COG2801	Transposase and inactivated derivatives
Rv2090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Rv2101	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Rv2102	COG4279	zinc finger
Rv2103c	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
Rv2109c	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Rv2123	COG5651	PPE family
Rv2124c	COG0646	methionine synthase
Rv2124c	COG1410	methionine synthase
Rv2129c	COG1028	Short-chain dehydrogenase reductase Sdr
Rv2141c	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Rv2153c	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Rv2155c	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Rv2163c	COG0768	penicillin binding
Rv2178c	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Rv2187	COG1022	Amp-dependent synthetase and ligase
Rv2208	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Rv2213	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Rv2217	COG0321	lipoyl(octanoyl) transferase activity
Rv2226	COG5607	PFAM CHAD domain containing protein
Rv2226	COG3025	triphosphatase activity
Rv2228c	COG0406	alpha-ribazole phosphatase activity
Rv2228c	COG0328	RNA-DNA hybrid ribonuclease activity
Rv2231A	COG3744	PilT protein domain protein
Rv2236c	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Rv2263	COG4221	oxidoreductase activity
Rv2277c	COG0584	glycerophosphoryl diester phosphodiesterase
Rv2307c	COG1073	alpha beta
Rv2308	COG2442	InterPro IPR007367
Rv2317	COG0395	ABC-type sugar transport system, permease component
Rv2320c	COG0531	amino acid
Rv2321c	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Rv2322c	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Rv2323c	COG1834	amidinotransferase
Rv2324	COG1522	sequence-specific DNA binding
Rv2329c	COG2223	nitrite transmembrane transporter activity
Rv2333c	COG0477	Major facilitator Superfamily
Rv2335	COG1045	serine acetyltransferase
Rv2338c	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Rv2371	COG0657	acetylesterase activity
Rv2377c	COG3251	PFAM MbtH domain protein
Rv2380c	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Rv2383c	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
Rv2383c	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Rv2384	COG1021	2,3-dihydroxybenzoate-AMP ligase
Rv2395	COG1297	OPT oligopeptide transporter protein
Rv2398c	COG4208	sulfate ABC transporter
Rv2400c	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Rv2402	COG3387	PFAM Glycoside hydrolase 15-related
Rv2407	COG1234	tRNA 3'-trailer cleavage
Rv2409c	COG1305	Transglutaminase-like
Rv2415c	COG1596	polysaccharide export
Rv2415c	COG1555	photosystem II stabilization
Rv2418c	COG2755	lipolytic protein G-D-S-L family
Rv2420c	COG0799	negative regulation of ribosome biogenesis
Rv2421c	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Rv2426c	COG0542	response to heat
Rv2430c	COG5651	PPE family
Rv2434c	COG0668	transmembrane transport
Rv2435c	COG5002	protein histidine kinase activity
Rv2436	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Rv2439c	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Rv2443	COG1301	dicarboxylic acid transport
Rv2444c	COG1530	ribonuclease E activity
Rv2447c	COG0285	dihydrofolate synthase activity
Rv2449c	COG3268	Saccharopine dehydrogenase
Rv2450c	COG1388	LysM domain
Rv2454c	COG1013	pyruvate-flavodoxin oxidoreductase activity
Rv2455c	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Rv2455c	COG0674	pyruvate-flavodoxin oxidoreductase activity
Rv2458	COG2040	homocysteine
Rv2462c	COG0544	peptidyl-prolyl cis-trans isomerase activity
Rv2463	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Rv2466c	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Rv2471	COG0366	Alpha amylase catalytic
Rv2475c	COG0824	Thioesterase
Rv2476c	COG2902	Dehydrogenase
Rv2482c	COG2937	Belongs to the GPAT DAPAT family
Rv2487c	COG0657	acetylesterase activity
Rv2494	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
Rv2495c	COG0508	dehydrogenase complex catalyzes the overall conversion of
Rv2499c	COG2030	dehydratase
Rv2500c	COG1960	acyl-CoA dehydrogenase activity
Rv2502c	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Rv2505c	COG0318	PFAM AMP-dependent synthetase and ligase
Rv2509	COG0300	oxidoreductase activity
Rv2510c	COG0433	COG0433 Predicted ATPase
Rv2525c	COG3757	hydrolase, family 25
Rv2528c	COG1715	Restriction endonuclease
Rv2533c	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Rv2546	COG1487	ribonuclease activity
Rv2553c	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Rv2555c	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Rv2556c	COG0432	Pfam Uncharacterised protein family UPF0047
Rv2560	COG5473	translation initiation factor activity
Rv2565	COG1752	Esterase of the alpha-beta hydrolase superfamily
Rv2565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Rv2567	COG2308	Evidence 4 Homologs of previously reported genes of
Rv2567	COG2307	Protein conserved in bacteria
Rv2579	COG0596	Alpha beta hydrolase
Rv2584c	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Rv2585c	COG0747	negative chemotaxis
Rv2586c	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Rv2590	COG3320	Male sterility
Rv2590	COG1022	Amp-dependent synthetase and ligase
Rv2605c	COG1946	Acyl-CoA thioesterase
Rv2608	COG5651	PPE family
Rv2611c	COG1560	Kdo2-lipid A biosynthetic process
Rv2615c	COG3391	amine dehydrogenase activity
Rv2616	COG4762	Protein conserved in bacteria
Rv2627c	COG1073	alpha beta
Rv2642	COG0640	Transcriptional regulator
Rv2643	COG0798	PFAM Bile acid sodium symporter
Rv2646	COG4974	Belongs to the 'phage' integrase family
Rv2674	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Rv2684	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Rv2688c	COG1131	(ABC) transporter
Rv2690c	COG0531	amino acid
Rv2691	COG0569	domain protein
Rv2702	COG1940	carbohydrate kinase activity
Rv2720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Rv2723	COG0861	Integral membrane protein TerC family
Rv2724c	COG1960	acyl-CoA dehydrogenase activity
Rv2725c	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Rv2731	COG1196	nuclear chromosome segregation
Rv2740	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
Rv2741	COG3391	amine dehydrogenase activity
Rv2747	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Rv2756c	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Rv2766c	COG1028	Short-chain dehydrogenase reductase Sdr
Rv2773c	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Rv2779c	COG1522	sequence-specific DNA binding
Rv2780	COG0686	Belongs to the AlaDH PNT family
Rv2782c	COG0612	Peptidase, M16
Rv2789c	COG1960	acyl-CoA dehydrogenase activity
Rv2790c	COG0183	Belongs to the thiolase family
Rv2801A	COG3609	addiction module antidote protein, CC2985 family
Rv2801c	COG2337	Toxic component of a toxin-antitoxin (TA) module
Rv2823c	COG1353	crispr-associated protein
Rv2829c	COG3744	PilT protein domain protein
Rv2830c	COG4118	positive regulation of growth
Rv2833c	COG1653	transport
Rv2834c	COG0395	ABC-type sugar transport system, permease component
Rv2837c	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Rv2847c	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Rv2847c	COG1648	precorrin-2 dehydrogenase activity
Rv2856	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
Rv2859c	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Rv2865	COG2161	toxin-antitoxin pair type II binding
Rv2866	COG2026	Addiction module toxin, RelE StbE family
Rv2874	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Rv2874	COG0785	Cytochrome C biogenesis protein
Rv2884	COG0745	RESPONSE REGULATOR receiver
Rv2889c	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Rv2897c	COG0606	chelatase, subunit chli
Rv2911	COG1686	Belongs to the peptidase S11 family
Rv2917	COG1061	Type III restriction enzyme res subunit
Rv2918c	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Rv2931	COG3321	synthase
Rv2931	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Rv2946c	COG4221	oxidoreductase activity
Rv2946c	COG3321	synthase
Rv2946c	COG0604	alcohol dehydrogenase
Rv2946c	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Rv2947c	COG3321	synthase
Rv2950c	COG0318	PFAM AMP-dependent synthetase and ligase
Rv2958c	COG1819	glycosyl
Rv2963	COG0701	Predicted permease
Rv2966c	COG0742	ribosomal rna small subunit methyltransferase
Rv2967c	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Rv2970A	COG0656	L-ascorbic acid biosynthetic process
Rv2974c	COG1461	Dihydroxyacetone kinase
Rv2981c	COG1181	Belongs to the D-alanine--D-alanine ligase family
Rv2982c	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Rv2988c	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Rv2993c	COG0179	Fumarylacetoacetate (FAA) hydrolase
Rv2994	COG2271	Major facilitator Superfamily
Rv2995c	COG0473	3-isopropylmalate dehydrogenase activity
Rv2998A	COG2972	Histidine kinase
Rv3000	COG0390	transport system, permease component
Rv3005c	COG2259	Doxx family
Rv3011c	COG0154	amidase activity
Rv3034c	COG0110	maltose O-acetyltransferase activity
Rv3035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Rv3041c	COG1119	ATPase activity
Rv3042c	COG0560	Phosphoserine phosphatase
Rv3042c	COG3830	Belongs to the UPF0237 family
Rv3050c	COG1309	transcriptional regulator
Rv3060c	COG2186	Transcriptional regulator
Rv3061c	COG1960	acyl-CoA dehydrogenase activity
Rv3062	COG1793	dna ligase
Rv3063	COG1966	Carbon starvation protein
Rv3079c	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Rv3092c	COG2354	Protein conserved in bacteria
Rv3095	COG1733	regulation of RNA biosynthetic process
Rv3097c	COG0657	acetylesterase activity
Rv3098A	COG2337	Toxic component of a toxin-antitoxin (TA) module
Rv3101c	COG2177	Part of the ABC transporter FtsEX involved in
Rv3102c	COG2884	Cell division ATP-binding protein ftsE
Rv3104c	COG0668	transmembrane transport
Rv3107c	COG0277	FAD linked oxidase domain protein
Rv3110	COG2154	pterin-4-alpha-carbinolamine dehydratase
Rv3112	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Rv3121	COG2124	cytochrome p450
Rv3124	COG3629	intracellular signal transduction
Rv3130c	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Rv3135	COG5651	PPE family
Rv3137	COG0483	inositol monophosphate 1-phosphatase activity
Rv3140	COG1960	acyl-CoA dehydrogenase activity
Rv3151	COG1034	ATP synthesis coupled electron transport
Rv3153	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Rv3164c	COG0714	Associated with various cellular activities
Rv3173c	COG1309	transcriptional regulator
Rv3175	COG0154	amidase activity
Rv3178	COG0748	coenzyme F420 binding
Rv3182	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
Rv3183	COG1396	sequence-specific DNA binding
Rv3191c	COG2826	transposase and inactivated derivatives, IS30 family
Rv3197	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Rv3199c	COG2816	NAD+ diphosphatase activity
Rv3201c	COG0210	DNA helicase
Rv3203	COG0596	Alpha beta hydrolase
Rv3204	COG3695	enzyme binding
Rv3211	COG0513	Belongs to the DEAD box helicase family
Rv3214	COG0406	alpha-ribazole phosphatase activity
Rv3218	COG1597	lipid kinase activity
Rv3224	COG1028	Short-chain dehydrogenase reductase Sdr
Rv3224B	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Rv3226c	COG2135	peptidase activity
Rv3228	COG1162	GTPase activity
Rv3232c	COG2326	polyphosphate kinase activity
Rv3236c	COG4651	solute:proton antiporter activity
Rv3236c	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Rv3238c	COG2020	methyltransferase activity
Rv3241c	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Rv3245c	COG5000	phosphorelay sensor kinase activity
Rv3245c	COG5002	protein histidine kinase activity
Rv3252c	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Rv3253c	COG0531	amino acid
Rv3254	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Rv3255c	COG1482	cell wall glycoprotein biosynthetic process
Rv3257c	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Rv3267	COG1316	TRANSCRIPTIONal
Rv3272	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Rv3273	COG0659	secondary active sulfate transmembrane transporter activity
Rv3280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Rv3282	COG0424	maF-like protein
Rv3285	COG4770	biotin carboxylase activity
Rv3291c	COG1522	sequence-specific DNA binding
Rv3293	COG1012	belongs to the aldehyde dehydrogenase family
Rv3295	COG1309	transcriptional regulator
Rv3296	COG1201	RNA secondary structure unwinding
Rv3300c	COG0564	pseudouridine synthase activity
Rv3305c	COG1473	amidohydrolase
Rv3305c	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Rv3308	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Rv3310	COG3511	phospholipase C
Rv3316	COG2009	succinate dehydrogenase
Rv3318	COG1053	succinate dehydrogenase
Rv3319	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Rv3328c	COG1595	DNA-templated transcription, initiation
Rv3329	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Rv3330	COG1686	Belongs to the peptidase S11 family
Rv3331	COG2814	Major facilitator Superfamily
Rv3332	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Rv3334	COG0789	Transcriptional regulator
Rv3335c	COG1295	ribonuclease BN
Rv3340	COG2873	o-acetylhomoserine
Rv3343c	COG5651	PPE family
Rv3345c	COG0657	acetylesterase activity
Rv3347c	COG5651	PPE family
Rv3347c	COG5651	PPE family
Rv3350c	COG5651	PPE family
Rv3350c	COG5651	PPE family
Rv3350c	COG5651	PPE family
Rv3352c	COG0277	FAD linked oxidase domain protein
Rv3356c	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Rv3359	COG0446	pyridine nucleotide-disulphide oxidoreductase
Rv3359	COG1902	pentaerythritol trinitrate reductase activity
Rv3360	COG1131	(ABC) transporter
Rv3360	COG0842	Transport permease protein
Rv3360	COG1716	ATPase activity
Rv3361c	COG1357	PFAM Pentapeptide repeats (8 copies)
Rv3364c	COG2018	Roadblock/LC7 domain
Rv3366	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Rv3371	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Rv3373	COG1024	Enoyl-CoA hydratase
Rv3377c	COG1657	PFAM Prenyltransferase squalene oxidase
Rv3379c	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Rv3384c	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
Rv3390	COG0406	alpha-ribazole phosphatase activity
Rv3392c	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Rv3399	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Rv3408	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
Rv3420c	COG0456	acetyltransferase
Rv3425	COG5651	PPE family
Rv3426	COG5651	PPE family
Rv3427c	COG1484	DNA-dependent DNA replication
Rv3428c	COG4584	PFAM Integrase catalytic
Rv3430c	COG2801	Transposase and inactivated derivatives
Rv3432c	COG0076	glutamate decarboxylase activity
Rv3447c	COG1674	ftsk spoiiie
Rv3449	COG1404	Belongs to the peptidase S8 family
Rv3459c	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Rv3466	COG1403	HNH endonuclease
Rv3467	COG1403	HNH endonuclease
Rv3468c	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Rv3469c	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Rv3470c	COG0028	Belongs to the TPP enzyme family
Rv3476c	COG0477	Major facilitator Superfamily
Rv3478	COG5651	PPE family
Rv3479	COG1752	Esterase of the alpha-beta hydrolase superfamily
Rv3480c	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Rv3484	COG1316	TRANSCRIPTIONal
Rv3485c	COG1028	Short-chain dehydrogenase reductase Sdr
Rv3486	COG2259	Doxx family
Rv3487c	COG0657	acetylesterase activity
Rv3488	COG1695	Transcriptional regulator
Rv3490	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Rv3495c	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Rv3500c	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Rv3501c	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Rv3504	COG1960	acyl-CoA dehydrogenase activity
Rv3505	COG1960	acyl-CoA dehydrogenase activity
Rv3507	COG0657	acetylesterase activity
Rv3508	COG0657	acetylesterase activity
Rv3509c	COG0028	Belongs to the TPP enzyme family
Rv3511	COG0657	acetylesterase activity
Rv3514	COG0657	acetylesterase activity
Rv3516	COG1024	Enoyl-CoA hydratase
Rv3518c	COG2124	cytochrome p450
Rv3520c	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Rv3522	COG0183	Belongs to the thiolase family
Rv3523	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Rv3526	COG4638	Rieske (2fe-2S)
Rv3530c	COG1028	Short-chain dehydrogenase reductase Sdr
Rv3542c	COG2030	dehydratase
Rv3543c	COG1960	acyl-CoA dehydrogenase activity
Rv3544c	COG1960	acyl-CoA dehydrogenase activity
Rv3546	COG0183	Belongs to the thiolase family
Rv3548c	COG1028	Short-chain dehydrogenase reductase Sdr
Rv3550	COG1024	Enoyl-CoA hydratase
Rv3554	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Rv3556c	COG0183	Belongs to the thiolase family
Rv3560c	COG1960	acyl-CoA dehydrogenase activity
Rv3561	COG0318	PFAM AMP-dependent synthetase and ligase
Rv3562	COG1960	acyl-CoA dehydrogenase activity
Rv3563	COG1960	acyl-CoA dehydrogenase activity
Rv3564	COG1960	acyl-CoA dehydrogenase activity
Rv3565	COG0436	Aminotransferase
Rv3573c	COG1960	acyl-CoA dehydrogenase activity
Rv3574	COG1309	transcriptional regulator
Rv3575c	COG1609	Transcriptional regulator
Rv3586	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Rv3590c	COG0657	acetylesterase activity
Rv3594	COG0739	heme binding
Rv3596c	COG0542	response to heat
Rv3617	COG2267	carboxylic ester hydrolase activity
Rv3627c	COG2027	D-alanyl-D-alanine carboxypeptidase
Rv3630	COG2244	polysaccharide biosynthetic process
Rv3641c	COG2184	nucleotidyltransferase activity
Rv3644c	COG0470	DNA polymerase III
Rv3649	COG1111	helicase
Rv3649	COG1205	dead DEAH box helicase
Rv3650	COG0657	acetylesterase activity
Rv3653	COG0657	acetylesterase activity
Rv3663c	COG4172	Belongs to the ABC transporter superfamily
Rv3665c	COG0601	transmembrane transport
Rv3672c	COG0494	nUDIX hydrolase
Rv3677c	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Rv3683	COG1408	metallophosphoesterase
Rv3684	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Rv3692	COG0714	Associated with various cellular activities
Rv3696c	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Rv3702c	COG0121	glutamine amidotransferase
Rv3703c	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Rv3712	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Rv3717	COG0860	N-Acetylmuramoyl-L-alanine amidase
Rv3720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Rv3722c	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Rv3726	COG1063	alcohol dehydrogenase
Rv3727	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Rv3727	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Rv3728	COG0477	Major facilitator Superfamily
Rv3729	COG2226	methyltransferase
Rv3731	COG1793	dna ligase
Rv3742c	COG2072	flavoprotein involved in K transport
Rv3744	COG0640	Transcriptional regulator
Rv3749c	COG1569	PIN domain
Rv3750c	COG3311	Transcriptional regulator
Rv3752c	COG0590	tRNA wobble adenosine to inosine editing
Rv3754	COG0287	Prephenate dehydrogenase
Rv3758c	COG1125	glycine betaine transport
Rv3758c	COG0517	IMP dehydrogenase activity
Rv3760	COG5416	Lipopolysaccharide assembly protein A domain
Rv3762c	COG2015	COG2015, Alkyl sulfatase and related hydrolases
Rv3764c	COG2205	protein histidine kinase activity
Rv3765c	COG0745	RESPONSE REGULATOR receiver
Rv3766	COG0739	heme binding
Rv3772	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Rv3776	COG1403	HNH endonuclease
Rv3784	COG1088	dTDP-glucose 4,6-dehydratase activity
Rv3786c	COG1216	Glycosyl transferase, family 2
Rv3786c	COG0739	heme binding
Rv3793	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Rv3796	COG1234	tRNA 3'-trailer cleavage
Rv3797	COG1960	acyl-CoA dehydrogenase activity
Rv3799c	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Rv3801c	COG0318	PFAM AMP-dependent synthetase and ligase
Rv3805c	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Rv3808c	COG1216	Glycosyl transferase, family 2
Rv3812	COG3391	amine dehydrogenase activity
Rv3813c	COG0561	phosphatase activity
Rv3820c	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Rv3822	COG5651	PPE family
Rv3823c	COG2409	Drug exporters of the RND superfamily
Rv3823c	COG1511	domain protein
Rv3833	COG2207	Transcriptional regulator
Rv3840	COG1316	TRANSCRIPTIONal
Rv3848	COG2119	membrane
Rv3856c	COG1796	DNA polymerase
Rv3856c	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Rv3859c	COG0069	glutamate synthase activity
Rv3859c	COG0067	glutamate synthase
Rv3859c	COG0070	glutamate synthase
Rv3879c	COG4932	domain protein
Rv3883c	COG1404	Belongs to the peptidase S8 family
Rv3884c	COG0464	growth
Rv3886c	COG1404	Belongs to the peptidase S8 family
Rv3892c	COG5651	PPE family
Rv3894c	COG1674	ftsk spoiiie
Rv3911	COG1595	DNA-templated transcription, initiation
Rv3915	COG3409	Peptidoglycan-binding domain 1 protein
Rv3915	COG0860	N-Acetylmuramoyl-L-alanine amidase
Rv3918c	COG1192	Involved in chromosome partitioning