locus-tag	class	description
JDM601_0002	COG0592	DNA-directed DNA polymerase activity
JDM601_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JDM601_0004	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JDM601_0005	COG0187	DNA topoisomerase II activity
JDM601_0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JDM601_0006	COG1372	Participates in initiation and elongation during chromosome replication
JDM601_0021	COG1716	ATPase activity
JDM601_0026	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JDM601_0027	COG0187	DNA topoisomerase II activity
JDM601_0028	COG1309	transcriptional regulator
JDM601_0029	COG2072	flavoprotein involved in K transport
JDM601_0033	COG1063	alcohol dehydrogenase
JDM601_0047	COG0464	growth
JDM601_0049	COG1404	Belongs to the peptidase S8 family
JDM601_0067	COG0346	lactoylglutathione lyase activity
JDM601_0070	COG2070	2-Nitropropane dioxygenase
JDM601_0081	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JDM601_0088	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JDM601_0094	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JDM601_0095	COG1012	belongs to the aldehyde dehydrogenase family
JDM601_0096	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_0099	COG1309	transcriptional regulator
JDM601_0100	COG1403	HNH endonuclease
JDM601_0102	COG0277	FAD linked oxidase domain protein
JDM601_0103	COG1309	transcriptional regulator
JDM601_0108	COG1946	Acyl-CoA thioesterase
JDM601_0111	COG2124	cytochrome p450
JDM601_0112	COG1063	alcohol dehydrogenase
JDM601_0116	COG2072	flavoprotein involved in K transport
JDM601_0121	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JDM601_0126	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JDM601_0141	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JDM601_0151	COG2267	carboxylic ester hydrolase activity
JDM601_0156	COG0129	dihydroxy-acid dehydratase activity
JDM601_0158	COG1937	Protein conserved in bacteria
JDM601_0160	COG1376	ErfK ybiS ycfS ynhG family protein
JDM601_0161	COG3590	peptidase
JDM601_0168	COG2409	Drug exporters of the RND superfamily
JDM601_0171	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JDM601_0174	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JDM601_0180	COG0406	alpha-ribazole phosphatase activity
JDM601_0183	COG1960	acyl-CoA dehydrogenase activity
JDM601_0184	COG1960	acyl-CoA dehydrogenase activity
JDM601_0188	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_0191	COG1960	acyl-CoA dehydrogenase activity
JDM601_0195	COG0500	methyltransferase
JDM601_0197	COG3011	Protein conserved in bacteria
JDM601_0211	COG1846	Transcriptional regulator
JDM601_0213	COG0655	NAD(P)H dehydrogenase (quinone) activity
JDM601_0214	COG1309	transcriptional regulator
JDM601_0218	COG4981	capsule polysaccharide biosynthetic process
JDM601_0220	COG1472	Belongs to the glycosyl hydrolase 3 family
JDM601_0226	COG0183	Belongs to the thiolase family
JDM601_0228	COG4977	sequence-specific DNA binding
JDM601_0229	COG1960	acyl-CoA dehydrogenase activity
JDM601_0233	COG0667	Aldo Keto reductase
JDM601_0235	COG1053	succinate dehydrogenase
JDM601_0239	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JDM601_0239	COG2146	nitrite reductase [NAD(P)H] activity
JDM601_0241	COG2146	nitrite reductase [NAD(P)H] activity
JDM601_0245	COG2223	nitrite transmembrane transporter activity
JDM601_0248	COG1984	allophanate hydrolase subunit 2
JDM601_0255	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_0256	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_0258	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_0260	COG1960	acyl-CoA dehydrogenase activity
JDM601_0261	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JDM601_0267	COG1921	L-seryl-tRNASec selenium transferase activity
JDM601_0268	COG0709	Synthesizes selenophosphate from selenide and ATP
JDM601_0273	COG0832	Belongs to the urease beta subunit family
JDM601_0273	COG0831	urea catabolic process
JDM601_0276	COG0437	4 iron, 4 sulfur cluster binding
JDM601_0278	COG0243	molybdopterin cofactor binding
JDM601_0278	COG3383	formate dehydrogenase (NAD+) activity
JDM601_0289	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JDM601_0299	COG1404	Belongs to the peptidase S8 family
JDM601_0303	COG0778	Nitroreductase
JDM601_0305	COG0671	phosphoesterase, PA-phosphatase related
JDM601_0322	COG0717	Belongs to the dCTP deaminase family
JDM601_0330	COG2181	nitrate reductase activity
JDM601_0330	COG0247	lactate metabolic process
JDM601_0338	COG0443	Heat shock 70 kDa protein
JDM601_0339	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JDM601_0341	COG0789	Transcriptional regulator
JDM601_0346	COG0542	response to heat
JDM601_0353	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JDM601_0361	COG1994	Peptidase M50
JDM601_0363	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JDM601_0367	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JDM601_0368	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JDM601_0370	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_0371	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JDM601_0382	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JDM601_0388	COG2022	thiamine diphosphate biosynthetic process
JDM601_0390	COG2234	aminopeptidase activity
JDM601_0391	COG1309	transcriptional regulator
JDM601_0392	COG2072	flavoprotein involved in K transport
JDM601_0394	COG0351	phosphomethylpyrimidine kinase
JDM601_0403	COG0242	peptide deformylase activity
JDM601_0407	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JDM601_0408	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JDM601_0409	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_0411	COG2124	cytochrome p450
JDM601_0412	COG1012	belongs to the aldehyde dehydrogenase family
JDM601_0415	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_0418	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JDM601_0419	COG1605	Chorismate mutase
JDM601_0421	COG0688	phosphatidylethanolamine metabolic process
JDM601_0428	COG4221	oxidoreductase activity
JDM601_0431	COG0459	protein refolding
JDM601_0433	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JDM601_0435	COG0667	Aldo Keto reductase
JDM601_0437	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JDM601_0437	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JDM601_0440	COG1012	belongs to the aldehyde dehydrogenase family
JDM601_0443	COG1505	serine-type exopeptidase activity
JDM601_0451	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JDM601_0452	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JDM601_0461	COG2733	membrane
JDM601_0466	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JDM601_0475	COG0438	transferase activity, transferring glycosyl groups
JDM601_0482	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JDM601_0483	COG1403	HNH endonuclease
JDM601_0487	COG0277	FAD linked oxidase domain protein
JDM601_0489	COG1136	(ABC) transporter
JDM601_0489	COG0577	efflux transmembrane transporter activity
JDM601_0500	COG2030	dehydratase
JDM601_0501	COG0560	Phosphoserine phosphatase
JDM601_0504	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JDM601_0509	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JDM601_0509	COG1796	DNA polymerase
JDM601_0523	COG0406	alpha-ribazole phosphatase activity
JDM601_0525	COG0785	Cytochrome C biogenesis protein
JDM601_0527	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JDM601_0533	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JDM601_0540	COG4221	oxidoreductase activity
JDM601_0542	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_0545	COG4948	Mandelate Racemase Muconate Lactonizing
JDM601_0552	COG2226	methyltransferase
JDM601_0557	COG0659	secondary active sulfate transmembrane transporter activity
JDM601_0560	COG2072	flavoprotein involved in K transport
JDM601_0561	COG1666	GTP binding
JDM601_0564	COG2226	methyltransferase
JDM601_0572	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_0591	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JDM601_0592	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JDM601_0597	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JDM601_0600	COG1201	RNA secondary structure unwinding
JDM601_0601	COG0210	DNA helicase
JDM601_0605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JDM601_0610	COG0537	adenosine 5'-monophosphoramidase activity
JDM601_0611	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JDM601_0624	COG3311	Transcriptional regulator
JDM601_0631	COG0653	protein targeting
JDM601_0632	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JDM601_0638	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_0639	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JDM601_0644	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JDM601_0645	COG1063	alcohol dehydrogenase
JDM601_0646	COG0205	6-phosphofructokinase activity
JDM601_0654	COG1752	Esterase of the alpha-beta hydrolase superfamily
JDM601_0656	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JDM601_0658	COG2030	dehydratase
JDM601_0659	COG2030	dehydratase
JDM601_0661	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JDM601_0665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JDM601_0666	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JDM601_0672	COG2337	Toxic component of a toxin-antitoxin (TA) module
JDM601_0687	COG1960	acyl-CoA dehydrogenase activity
JDM601_0695	COG0049	tRNA binding
JDM601_0696	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JDM601_0697	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JDM601_0699	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_0702	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_0707	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JDM601_0709	COG1024	Enoyl-CoA hydratase
JDM601_0710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JDM601_0711	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JDM601_0712	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JDM601_0712	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JDM601_0713	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JDM601_0715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JDM601_0718	COG0183	Belongs to the thiolase family
JDM601_0721	COG1024	Enoyl-CoA hydratase
JDM601_0722	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_0723	COG3173	Aminoglycoside phosphotransferase
JDM601_0725	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_0726	COG2188	Transcriptional regulator
JDM601_0727	COG3386	PFAM SMP-30 Gluconolaconase
JDM601_0729	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JDM601_0730	COG1960	acyl-CoA dehydrogenase activity
JDM601_0732	COG1960	acyl-CoA dehydrogenase activity
JDM601_0733	COG1960	acyl-CoA dehydrogenase activity
JDM601_0734	COG0028	Belongs to the TPP enzyme family
JDM601_0737	COG1024	Enoyl-CoA hydratase
JDM601_0738	COG0183	Belongs to the thiolase family
JDM601_0739	COG1960	acyl-CoA dehydrogenase activity
JDM601_0743	COG2259	Doxx family
JDM601_0745	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_0746	COG1024	Enoyl-CoA hydratase
JDM601_0757	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JDM601_0764	COG4974	Belongs to the 'phage' integrase family
JDM601_0765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JDM601_0770	COG2801	Transposase and inactivated derivatives
JDM601_0771	COG2963	transposase activity
JDM601_0772	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JDM601_0784	COG0183	Belongs to the thiolase family
JDM601_0785	COG1024	Enoyl-CoA hydratase
JDM601_0785	COG1250	3-hydroxyacyl-CoA dehydrogenase
JDM601_0787	COG2813	Specifically methylates the guanine in position
JDM601_0789	COG1061	Type III restriction enzyme res subunit
JDM601_0793	COG0521	Mo-molybdopterin cofactor biosynthetic process
JDM601_0797	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JDM601_0798	COG1278	Cold shock
JDM601_0800	COG0435	Glutathione S-transferase
JDM601_0807	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JDM601_0811	COG3396	Phenylacetate-CoA oxygenase
JDM601_0814	COG0259	pyridoxamine-phosphate oxidase activity
JDM601_0817	COG0545	Peptidyl-prolyl cis-trans isomerase
JDM601_0824	COG1132	(ABC) transporter
JDM601_0825	COG1132	(ABC) transporter
JDM601_0828	COG1024	Enoyl-CoA hydratase
JDM601_0830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JDM601_0832	COG0488	(ABC) transporter
JDM601_0833	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDM601_0840	COG1733	regulation of RNA biosynthetic process
JDM601_0841	COG0243	molybdopterin cofactor binding
JDM601_0843	COG3550	peptidyl-serine autophosphorylation
JDM601_0852	COG1960	acyl-CoA dehydrogenase activity
JDM601_0853	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_0855	COG1309	transcriptional regulator
JDM601_0857	COG0640	Transcriptional regulator
JDM601_0858	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JDM601_0866	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JDM601_0867	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JDM601_0868	COG1993	acr, cog1993
JDM601_0869	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JDM601_0870	COG1960	acyl-CoA dehydrogenase activity
JDM601_0882	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JDM601_0884	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JDM601_0889	COG1950	PFAM Membrane protein of
JDM601_0890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JDM601_0892	COG0166	Belongs to the GPI family
JDM601_0896	COG0739	heme binding
JDM601_0897	COG0045	succinate-CoA ligase (ADP-forming) activity
JDM601_0905	COG0138	bifunctional purine biosynthesis protein purh
JDM601_0907	COG0657	acetylesterase activity
JDM601_0910	COG4867	von Willebrand factor, type A
JDM601_0913	COG2197	response regulator
JDM601_0914	COG2111	Na H antiporter
JDM601_0914	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JDM601_0918	COG2212	antiporter activity
JDM601_0925	COG1024	Enoyl-CoA hydratase
JDM601_0928	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JDM601_0929	COG1960	acyl-CoA dehydrogenase activity
JDM601_0932	COG0745	RESPONSE REGULATOR receiver
JDM601_0933	COG2205	protein histidine kinase activity
JDM601_0934	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JDM601_0935	COG0521	Mo-molybdopterin cofactor biosynthetic process
JDM601_0935	COG0315	cyclic pyranopterin monophosphate synthase activity
JDM601_0937	COG1970	mechanosensitive ion channel activity
JDM601_0940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JDM601_0941	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JDM601_0950	COG1309	transcriptional regulator
JDM601_0953	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JDM601_0954	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JDM601_0954	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JDM601_0958	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JDM601_0961	COG0446	pyridine nucleotide-disulphide oxidoreductase
JDM601_0964	COG0084	hydrolase, TatD family'
JDM601_0969	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JDM601_0970	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_0971	COG0193	aminoacyl-tRNA hydrolase activity
JDM601_0972	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JDM601_0982	COG1309	transcriptional regulator
JDM601_0984	COG3956	TIGRFAM MazG family protein
JDM601_1006	COG2226	methyltransferase
JDM601_1009	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_1017	COG1024	Enoyl-CoA hydratase
JDM601_1020	COG0183	Belongs to the thiolase family
JDM601_1022	COG0657	acetylesterase activity
JDM601_1024	COG1714	RDD family
JDM601_1026	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JDM601_1028	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JDM601_1030	COG1331	Highly conserved protein containing a thioredoxin domain
JDM601_1031	COG3631	Ketosteroid isomerase-related protein
JDM601_1037	COG0572	uridine kinase
JDM601_1039	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JDM601_1041	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JDM601_1044	COG0726	polysaccharide deacetylase
JDM601_1045	COG2015	COG2015, Alkyl sulfatase and related hydrolases
JDM601_1046	COG1403	HNH endonuclease
JDM601_1058	COG1570	exodeoxyribonuclease VII activity
JDM601_1060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JDM601_1062	COG0012	GTP binding
JDM601_1068	COG2814	Major facilitator Superfamily
JDM601_1076	COG2267	carboxylic ester hydrolase activity
JDM601_1078	COG3800	Transcriptional regulator
JDM601_1078	COG1396	sequence-specific DNA binding
JDM601_1081	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JDM601_1086	COG1024	Enoyl-CoA hydratase
JDM601_1092	COG1309	transcriptional regulator
JDM601_1102	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JDM601_1106	COG2124	cytochrome p450
JDM601_1107	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_1109	COG0714	Associated with various cellular activities
JDM601_1114	COG2124	cytochrome p450
JDM601_1115	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_1117	COG0183	Belongs to the thiolase family
JDM601_1118	COG1024	Enoyl-CoA hydratase
JDM601_1121	COG1024	Enoyl-CoA hydratase
JDM601_1122	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JDM601_1127	COG3654	unkown
JDM601_1132	COG2267	carboxylic ester hydrolase activity
JDM601_1138	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JDM601_1140	COG3467	pyridoxamine 5'-phosphate
JDM601_1146	COG2154	pterin-4-alpha-carbinolamine dehydratase
JDM601_1147	COG1051	belongs to the nudix hydrolase family
JDM601_1150	COG1140	nitrate reductase beta subunit
JDM601_1159	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JDM601_1162	COG1902	pentaerythritol trinitrate reductase activity
JDM601_1162	COG0446	pyridine nucleotide-disulphide oxidoreductase
JDM601_1166	COG0657	acetylesterase activity
JDM601_1167	COG5651	PPE family
JDM601_1169	COG2313	pseudouridylate synthase activity
JDM601_1170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JDM601_1172	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_1180	COG1611	Belongs to the LOG family
JDM601_1183	COG0463	Glycosyl transferase, family 2
JDM601_1185	COG0519	Catalyzes the synthesis of GMP from XMP
JDM601_1188	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JDM601_1191	COG3559	Exporter of polyketide antibiotics
JDM601_1192	COG1131	(ABC) transporter
JDM601_1193	COG1309	transcriptional regulator
JDM601_1194	COG4122	O-methyltransferase activity
JDM601_1196	COG5662	AntiSigma factor
JDM601_1197	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JDM601_1198	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JDM601_1202	COG2239	Acts as a magnesium transporter
JDM601_1211	COG0598	Magnesium transport protein CorA
JDM601_1216	COG0508	dehydrogenase complex catalyzes the overall conversion of
JDM601_1216	COG0567	Dehydrogenase, E1 component
JDM601_1224	COG0277	FAD linked oxidase domain protein
JDM601_1229	COG0657	acetylesterase activity
JDM601_1230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDM601_1237	COG1132	(ABC) transporter
JDM601_1250	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_1252	COG1309	transcriptional regulator
JDM601_1288	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDM601_1291	COG0018	arginyl-trna synthetase
JDM601_1292	COG0019	diaminopimelate decarboxylase activity
JDM601_1293	COG0460	homoserine dehydrogenase
JDM601_1294	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JDM601_1295	COG0083	homoserine kinase activity
JDM601_1299	COG2890	protein-(glutamine-N5) methyltransferase activity
JDM601_1303	COG0356	it plays a direct role in the translocation of protons across the membrane
JDM601_1304	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JDM601_1306	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JDM601_1306	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JDM601_1307	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JDM601_1313	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JDM601_1315	COG2963	transposase activity
JDM601_1316	COG2801	Transposase and inactivated derivatives
JDM601_1319	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JDM601_1321	COG2066	Belongs to the glutaminase family
JDM601_1321	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JDM601_1323	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JDM601_1326	COG0183	Belongs to the thiolase family
JDM601_1330	COG0058	SHG alpha-glucan phosphorylase activity
JDM601_1336	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JDM601_1339	COG3191	aminopeptidase activity
JDM601_1341	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JDM601_1343	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JDM601_1370	COG2801	Transposase and inactivated derivatives
JDM601_1371	COG2963	transposase activity
JDM601_1382	COG3757	hydrolase, family 25
JDM601_1385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JDM601_1395	COG0433	COG0433 Predicted ATPase
JDM601_1396	COG4221	oxidoreductase activity
JDM601_1400	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_1403	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JDM601_1405	COG1960	acyl-CoA dehydrogenase activity
JDM601_1406	COG2030	dehydratase
JDM601_1408	COG4948	Mandelate Racemase Muconate Lactonizing
JDM601_1410	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JDM601_1420	COG0508	dehydrogenase complex catalyzes the overall conversion of
JDM601_1424	COG0560	Phosphoserine phosphatase
JDM601_1427	COG0477	Major facilitator Superfamily
JDM601_1432	COG2902	Dehydrogenase
JDM601_1434	COG0366	Alpha amylase catalytic
JDM601_1439	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JDM601_1442	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JDM601_1446	COG0544	peptidyl-prolyl cis-trans isomerase activity
JDM601_1449	COG2040	homocysteine
JDM601_1450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JDM601_1452	COG0674	pyruvate-flavodoxin oxidoreductase activity
JDM601_1452	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JDM601_1453	COG1013	pyruvate-flavodoxin oxidoreductase activity
JDM601_1456	COG1388	LysM domain
JDM601_1457	COG3268	Saccharopine dehydrogenase
JDM601_1460	COG0285	dihydrofolate synthase activity
JDM601_1463	COG1530	ribonuclease E activity
JDM601_1466	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JDM601_1468	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JDM601_1473	COG2814	Major facilitator Superfamily
JDM601_1478	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JDM601_1480	COG0668	transmembrane transport
JDM601_1481	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JDM601_1482	COG0542	response to heat
JDM601_1487	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JDM601_1488	COG0799	negative regulation of ribosome biogenesis
JDM601_1490	COG2755	lipolytic protein G-D-S-L family
JDM601_1497	COG1960	acyl-CoA dehydrogenase activity
JDM601_1498	COG1960	acyl-CoA dehydrogenase activity
JDM601_1500	COG1596	polysaccharide export
JDM601_1500	COG1555	photosystem II stabilization
JDM601_1505	COG0517	IMP dehydrogenase activity
JDM601_1505	COG0516	GMP reductase activity
JDM601_1510	COG3387	PFAM Glycoside hydrolase 15-related
JDM601_1512	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JDM601_1514	COG4208	sulfate ABC transporter
JDM601_1515	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JDM601_1526	COG1937	Protein conserved in bacteria
JDM601_1528	COG1021	2,3-dihydroxybenzoate-AMP ligase
JDM601_1529	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JDM601_1529	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JDM601_1542	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JDM601_1547	COG1070	Carbohydrate kinase
JDM601_1550	COG0484	heat shock protein binding
JDM601_1552	COG2226	methyltransferase
JDM601_1555	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JDM601_1563	COG1381	Involved in DNA repair and RecF pathway recombination
JDM601_1565	COG0500	methyltransferase
JDM601_1566	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JDM601_1570	COG0423	glycine-tRNA ligase activity
JDM601_1575	COG0358	DNA primase activity
JDM601_1590	COG0395	ABC-type sugar transport system, permease component
JDM601_1591	COG1175	transmembrane transport
JDM601_1602	COG2020	methyltransferase activity
JDM601_1604	COG1595	DNA-templated transcription, initiation
JDM601_1609	COG2072	flavoprotein involved in K transport
JDM601_1616	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JDM601_1621	COG4221	oxidoreductase activity
JDM601_1622	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_1624	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_1625	COG1403	HNH endonuclease
JDM601_1629	COG0028	Belongs to the TPP enzyme family
JDM601_1632	COG0443	Heat shock 70 kDa protein
JDM601_1635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JDM601_1647	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_1650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JDM601_1651	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JDM601_1652	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JDM601_1666	COG0328	RNA-DNA hybrid ribonuclease activity
JDM601_1666	COG0406	alpha-ribazole phosphatase activity
JDM601_1667	COG1396	sequence-specific DNA binding
JDM601_1668	COG1045	serine acetyltransferase
JDM601_1670	COG0492	ferredoxin-NADP+ reductase activity
JDM601_1675	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JDM601_1678	COG0174	glutamine synthetase
JDM601_1682	COG0174	glutamine synthetase
JDM601_1686	COG0321	lipoyl(octanoyl) transferase activity
JDM601_1690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JDM601_1692	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JDM601_1693	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JDM601_1695	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JDM601_1696	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JDM601_1710	COG1845	cytochrome c oxidase, subunit III
JDM601_1716	COG1022	Amp-dependent synthetase and ligase
JDM601_1719	COG0003	Pfam Anion-transporting ATPase
JDM601_1725	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JDM601_1737	COG0768	penicillin binding
JDM601_1741	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JDM601_1743	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JDM601_1744	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JDM601_1754	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JDM601_1756	COG0167	dihydroorotate dehydrogenase activity
JDM601_1759	COG2409	Drug exporters of the RND superfamily
JDM601_1762	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JDM601_1767	COG1968	undecaprenyl-diphosphatase activity
JDM601_1768	COG0328	RNA-DNA hybrid ribonuclease activity
JDM601_1768	COG0406	alpha-ribazole phosphatase activity
JDM601_1772	COG0215	cysteine-tRNA ligase activity
JDM601_1773	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_1775	COG1410	methionine synthase
JDM601_1775	COG0646	methionine synthase
JDM601_1795	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JDM601_1797	COG1872	DUF167
JDM601_1799	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
JDM601_1800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JDM601_1804	COG2339	peptidase activity
JDM601_1805	COG0539	negative regulation of cytoplasmic translation
JDM601_1813	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JDM601_1824	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JDM601_1827	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JDM601_1828	COG0072	phenylalanine-tRNA ligase activity
JDM601_1828	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JDM601_1829	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JDM601_1831	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JDM601_1833	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JDM601_1834	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JDM601_1835	COG1438	arginine binding
JDM601_1836	COG0137	argininosuccinate synthase activity
JDM601_1837	COG0165	Argininosuccinate lyase
JDM601_1840	COG0488	(ABC) transporter
JDM601_1842	COG1309	transcriptional regulator
JDM601_1843	COG2835	tetraacyldisaccharide 4'-kinase activity
JDM601_1845	COG1131	(ABC) transporter
JDM601_1846	COG2094	Belongs to the DNA glycosylase MPG family
JDM601_1847	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JDM601_1848	COG0647	UMP catabolic process
JDM601_1855	COG0504	CTP synthase activity
JDM601_1862	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JDM601_1864	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JDM601_1865	COG1160	GTP binding
JDM601_1870	COG0582	viral genome integration into host DNA
JDM601_1874	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JDM601_1876	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JDM601_1878	COG0281	malic enzyme
JDM601_1879	COG0402	S-adenosylhomocysteine deaminase activity
JDM601_1880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDM601_1890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JDM601_1893	COG1674	ftsk spoiiie
JDM601_1899	COG1404	Belongs to the peptidase S8 family
JDM601_1916	COG0653	protein targeting
JDM601_1921	COG0509	glycine decarboxylation via glycine cleavage system
JDM601_1926	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JDM601_1926	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JDM601_1931	COG1253	flavin adenine dinucleotide binding
JDM601_1932	COG1253	flavin adenine dinucleotide binding
JDM601_1937	COG0406	alpha-ribazole phosphatase activity
JDM601_1938	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JDM601_1943	COG1252	NADH dehydrogenase
JDM601_1954	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JDM601_1962	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JDM601_1970	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
JDM601_1973	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JDM601_1978	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JDM601_1981	COG0714	Associated with various cellular activities
JDM601_1984	COG2070	2-Nitropropane dioxygenase
JDM601_1988	COG1546	Belongs to the CinA family
JDM601_1988	COG1058	Belongs to the CinA family
JDM601_1991	COG1490	D-aminoacyl-tRNA deacylase activity
JDM601_1994	COG3022	response to hydroperoxide
JDM601_2000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JDM601_2009	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_2016	COG1024	Enoyl-CoA hydratase
JDM601_2020	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JDM601_2022	COG0545	Peptidyl-prolyl cis-trans isomerase
JDM601_2023	COG2130	NADP-dependent
JDM601_2025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JDM601_2026	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JDM601_2028	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JDM601_2029	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JDM601_2035	COG0596	Alpha beta hydrolase
JDM601_2047	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_2058	COG2026	Addiction module toxin, RelE StbE family
JDM601_2059	COG2161	toxin-antitoxin pair type II binding
JDM601_2071	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JDM601_2075	COG1643	Atp-dependent helicase
JDM601_2077	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JDM601_2081	COG2226	methyltransferase
JDM601_2082	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JDM601_2084	COG3842	ATPase activity
JDM601_2085	COG0395	ABC-type sugar transport system, permease component
JDM601_2089	COG1116	anion transmembrane transporter activity
JDM601_2094	COG1335	isochorismatase
JDM601_2101	COG0463	Glycosyl transferase, family 2
JDM601_2103	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JDM601_2109	COG0300	oxidoreductase activity
JDM601_2114	COG4581	dead DEAH box helicase
JDM601_2122	COG1742	UPF0060 membrane protein
JDM601_2133	COG0134	indole-3-glycerol-phosphate synthase activity
JDM601_2135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JDM601_2140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JDM601_2141	COG0107	imidazoleglycerol-phosphate synthase activity
JDM601_2142	COG0483	inositol monophosphate 1-phosphatase activity
JDM601_2143	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JDM601_2147	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JDM601_2159	COG2801	Transposase and inactivated derivatives
JDM601_2163	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JDM601_2165	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JDM601_2165	COG2755	lipolytic protein G-D-S-L family
JDM601_2177	COG0789	Transcriptional regulator
JDM601_2182	COG3360	Dodecin
JDM601_2185	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JDM601_2186	COG0252	asparaginase activity
JDM601_2190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JDM601_2196	COG3396	Phenylacetate-CoA oxygenase
JDM601_2199	COG0300	oxidoreductase activity
JDM601_2201	COG0300	oxidoreductase activity
JDM601_2202	COG0657	acetylesterase activity
JDM601_2202	COG5651	PPE family
JDM601_2209	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JDM601_2216	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_2218	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JDM601_2225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JDM601_2231	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JDM601_2233	COG2304	oxidoreductase activity
JDM601_2235	COG0714	Associated with various cellular activities
JDM601_2237	COG0791	NLP P60 protein
JDM601_2237	COG3883	PFAM NLP P60 protein
JDM601_2239	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JDM601_2240	COG1309	transcriptional regulator
JDM601_2242	COG0488	(ABC) transporter
JDM601_2244	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JDM601_2247	COG1228	amidohydrolase
JDM601_2247	COG1228	amidohydrolase
JDM601_2249	COG2151	metal-sulfur cluster biosynthetic enzyme
JDM601_2252	COG0396	ATPase activity
JDM601_2265	COG0109	protoheme IX farnesyltransferase activity
JDM601_2268	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JDM601_2274	COG0149	triose-phosphate isomerase activity
JDM601_2275	COG0126	phosphoglycerate kinase activity
JDM601_2276	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JDM601_2282	COG0322	excinuclease ABC activity
JDM601_2285	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JDM601_2285	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JDM601_2301	COG2072	flavoprotein involved in K transport
JDM601_2302	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JDM601_2303	COG1309	transcriptional regulator
JDM601_2304	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JDM601_2310	COG0284	orotidine-5'-phosphate decarboxylase activity
JDM601_2312	COG0505	Belongs to the CarA family
JDM601_2315	COG0540	Belongs to the ATCase OTCase family
JDM601_2316	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JDM601_2318	COG1960	acyl-CoA dehydrogenase activity
JDM601_2325	COG2188	Transcriptional regulator
JDM601_2328	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JDM601_2330	COG0006	proline dipeptidase activity
JDM601_2333	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JDM601_2338	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JDM601_2339	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JDM601_2340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JDM601_2341	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JDM601_2342	COG0432	Pfam Uncharacterised protein family UPF0047
JDM601_2343	COG2301	Belongs to the HpcH HpaI aldolase family
JDM601_2344	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JDM601_2354	COG2050	protein possibly involved in aromatic compounds catabolism
JDM601_2355	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JDM601_2360	COG0657	acetylesterase activity
JDM601_2362	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JDM601_2363	COG0235	Class ii aldolase
JDM601_2364	COG1396	sequence-specific DNA binding
JDM601_2367	COG0124	histidyl-tRNA synthetase
JDM601_2368	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JDM601_2370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JDM601_2372	COG0747	negative chemotaxis
JDM601_2373	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JDM601_2379	COG0632	four-way junction helicase activity
JDM601_2387	COG1946	Acyl-CoA thioesterase
JDM601_2389	COG1309	transcriptional regulator
JDM601_2393	COG0438	transferase activity, transferring glycosyl groups
JDM601_2397	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JDM601_2399	COG4762	Protein conserved in bacteria
JDM601_2401	COG2070	2-Nitropropane dioxygenase
JDM601_2417	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JDM601_2420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JDM601_2430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JDM601_2431	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JDM601_2432	COG0531	amino acid
JDM601_2433	COG0569	domain protein
JDM601_2439	COG0756	dUTP diphosphatase activity
JDM601_2443	COG1940	carbohydrate kinase activity
JDM601_2456	COG4044	May play a role in the intracellular transport of hydrophobic ligands
JDM601_2457	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JDM601_2459	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JDM601_2460	COG0302	gtp cyclohydrolase
JDM601_2465	COG1960	acyl-CoA dehydrogenase activity
JDM601_2466	COG0513	Belongs to the DEAD box helicase family
JDM601_2467	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JDM601_2468	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JDM601_2469	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JDM601_2472	COG1196	nuclear chromosome segregation
JDM601_2476	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JDM601_2477	COG1126	abc transporter atp-binding protein
JDM601_2478	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JDM601_2479	COG0765	amino acid transport
JDM601_2480	COG0765	amino acid transport
JDM601_2483	COG1372	Participates in initiation and elongation during chromosome replication
JDM601_2483	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JDM601_2488	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
JDM601_2494	COG1396	sequence-specific DNA binding
JDM601_2496	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JDM601_2498	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JDM601_2499	COG1674	ftsk spoiiie
JDM601_2508	COG3214	Protein conserved in bacteria
JDM601_2510	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JDM601_2512	COG0477	Major facilitator Superfamily
JDM601_2518	COG1322	Protein conserved in bacteria
JDM601_2519	COG4770	biotin carboxylase activity
JDM601_2526	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JDM601_2527	COG0657	acetylesterase activity
JDM601_2534	COG0612	Peptidase, M16
JDM601_2535	COG1185	polyribonucleotide nucleotidyltransferase activity
JDM601_2537	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JDM601_2543	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_2546	COG0183	Belongs to the thiolase family
JDM601_2549	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JDM601_2559	COG1024	Enoyl-CoA hydratase
JDM601_2561	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JDM601_2562	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JDM601_2571	COG1648	precorrin-2 dehydrogenase activity
JDM601_2571	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JDM601_2574	COG1960	acyl-CoA dehydrogenase activity
JDM601_2576	COG2264	protein methyltransferase activity
JDM601_2578	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_2580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JDM601_2582	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_2590	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JDM601_2597	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JDM601_2600	COG0528	UMP kinase activity
JDM601_2602	COG3260	NADH ubiquinone oxidoreductase 20
JDM601_2606	COG0651	ATP synthesis coupled electron transport
JDM601_2607	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
JDM601_2607	COG3261	NADH dehydrogenase
JDM601_2609	COG0154	amidase activity
JDM601_2610	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JDM601_2614	COG4974	Belongs to the 'phage' integrase family
JDM601_2618	COG0606	chelatase, subunit chli
JDM601_2619	COG0792	nuclease activity
JDM601_2624	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JDM601_2627	COG0336	Belongs to the RNA methyltransferase TrmD family
JDM601_2629	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JDM601_2631	COG0228	four-way junction DNA binding
JDM601_2633	COG1686	Belongs to the peptidase S11 family
JDM601_2638	COG1309	transcriptional regulator
JDM601_2645	COG0494	nUDIX hydrolase
JDM601_2655	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JDM601_2659	COG3599	regulation of cell shape
JDM601_2668	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JDM601_2669	COG0742	ribosomal rna small subunit methyltransferase
JDM601_2670	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JDM601_2677	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JDM601_2678	COG1461	Dihydroxyacetone kinase
JDM601_2684	COG1181	Belongs to the D-alanine--D-alanine ligase family
JDM601_2690	COG0066	3-isopropylmalate dehydratase activity
JDM601_2691	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JDM601_2694	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JDM601_2695	COG0179	Fumarylacetoacetate (FAA) hydrolase
JDM601_2696	COG2271	Major facilitator Superfamily
JDM601_2697	COG0456	acetyltransferase
JDM601_2698	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JDM601_2699	COG1917	Cupin 2, conserved barrel domain protein
JDM601_2700	COG5285	phytanoyl-CoA dioxygenase
JDM601_2702	COG0154	amidase activity
JDM601_2706	COG1802	Transcriptional regulator
JDM601_2708	COG4638	Rieske (2fe-2S)
JDM601_2709	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
JDM601_2713	COG3485	protocatechuate 3,4-dioxygenase
JDM601_2714	COG3485	protocatechuate 3,4-dioxygenase
JDM601_2716	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JDM601_2721	COG0440	acetolactate synthase activity
JDM601_2729	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JDM601_2732	COG0205	6-phosphofructokinase activity
JDM601_2741	COG0482	sulfurtransferase activity
JDM601_2748	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JDM601_2754	COG2409	Drug exporters of the RND superfamily
JDM601_2758	COG0110	maltose O-acetyltransferase activity
JDM601_2759	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JDM601_2763	COG0406	alpha-ribazole phosphatase activity
JDM601_2764	COG0406	alpha-ribazole phosphatase activity
JDM601_2765	COG0406	alpha-ribazole phosphatase activity
JDM601_2768	COG1119	ATPase activity
JDM601_2774	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JDM601_2776	COG2267	carboxylic ester hydrolase activity
JDM601_2777	COG1064	alcohol dehydrogenase
JDM601_2780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JDM601_2782	COG1309	transcriptional regulator
JDM601_2790	COG0431	NADPH-dependent FMN reductase
JDM601_2796	COG0028	Belongs to the TPP enzyme family
JDM601_2797	COG1960	acyl-CoA dehydrogenase activity
JDM601_2799	COG1966	Carbon starvation protein
JDM601_2801	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JDM601_2802	COG1376	ErfK ybiS ycfS ynhG family protein
JDM601_2803	COG2124	cytochrome p450
JDM601_2806	COG0235	Class ii aldolase
JDM601_2808	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JDM601_2811	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JDM601_2819	COG1674	ftsk spoiiie
JDM601_2842	COG2884	Cell division ATP-binding protein ftsE
JDM601_2844	COG0668	transmembrane transport
JDM601_2848	COG0483	inositol monophosphate 1-phosphatase activity
JDM601_2850	COG1960	acyl-CoA dehydrogenase activity
JDM601_2853	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JDM601_2854	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JDM601_2856	COG1960	acyl-CoA dehydrogenase activity
JDM601_2862	COG0649	NAD binding
JDM601_2865	COG1034	ATP synthesis coupled electron transport
JDM601_2866	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JDM601_2867	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JDM601_2869	COG0713	ATP synthesis coupled electron transport
JDM601_2877	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JDM601_2885	COG2072	flavoprotein involved in K transport
JDM601_2887	COG2031	fatty acid transporter
JDM601_2891	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JDM601_2892	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JDM601_2906	COG3480	Lon protease (S16) C-terminal proteolytic domain
JDM601_2910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JDM601_2918	COG0596	Alpha beta hydrolase
JDM601_2926	COG0513	Belongs to the DEAD box helicase family
JDM601_2929	COG0406	alpha-ribazole phosphatase activity
JDM601_2934	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JDM601_2940	COG3237	CsbD-like
JDM601_2942	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_2943	COG1960	acyl-CoA dehydrogenase activity
JDM601_2944	COG1960	acyl-CoA dehydrogenase activity
JDM601_2946	COG1309	transcriptional regulator
JDM601_2949	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_2952	COG3850	Histidine kinase
JDM601_2952	COG5002	protein histidine kinase activity
JDM601_2953	COG0745	RESPONSE REGULATOR receiver
JDM601_2956	COG2135	peptidase activity
JDM601_2958	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDM601_2968	COG2326	polyphosphate kinase activity
JDM601_2971	COG0653	protein targeting
JDM601_2972	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JDM601_2977	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_2982	COG2201	protein-glutamate methylesterase activity
JDM601_2983	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JDM601_2984	COG5401	PFAM Sporulation and spore germination
JDM601_2988	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JDM601_2991	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JDM601_2992	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JDM601_2992	COG2972	Histidine kinase
JDM601_2995	COG0438	transferase activity, transferring glycosyl groups
JDM601_2996	COG2226	methyltransferase
JDM601_3004	COG1482	cell wall glycoprotein biosynthetic process
JDM601_3006	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JDM601_3011	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JDM601_3011	COG0778	Nitroreductase
JDM601_3018	COG1316	TRANSCRIPTIONal
JDM601_3026	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JDM601_3027	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JDM601_3032	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JDM601_3033	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JDM601_3036	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JDM601_3036	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JDM601_3037	COG0657	acetylesterase activity
JDM601_3039	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JDM601_3045	COG4770	biotin carboxylase activity
JDM601_3047	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDM601_3058	COG0300	oxidoreductase activity
JDM601_3068	COG0789	Transcriptional regulator
JDM601_3071	COG2890	protein-(glutamine-N5) methyltransferase activity
JDM601_3072	COG0028	Belongs to the TPP enzyme family
JDM601_3073	COG1573	uracil-dna glycosylase
JDM601_3075	COG3707	response regulator
JDM601_3079	COG0297	glycogen (starch) synthase activity
JDM601_3087	COG1982	Orn Lys Arg decarboxylase major
JDM601_3089	COG0693	protein deglycase activity
JDM601_3093	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JDM601_3098	COG4948	Mandelate Racemase Muconate Lactonizing
JDM601_3102	COG0723	plastoquinol--plastocyanin reductase activity
JDM601_3110	COG0745	RESPONSE REGULATOR receiver
JDM601_3115	COG1201	RNA secondary structure unwinding
JDM601_3120	COG0564	pseudouridine synthase activity
JDM601_3121	COG2801	Transposase and inactivated derivatives
JDM601_3125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JDM601_3129	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JDM601_3129	COG1473	amidohydrolase
JDM601_3133	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JDM601_3143	COG2009	succinate dehydrogenase
JDM601_3148	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JDM601_3149	COG1595	DNA-templated transcription, initiation
JDM601_3152	COG1686	Belongs to the peptidase S11 family
JDM601_3154	COG2814	Major facilitator Superfamily
JDM601_3155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JDM601_3169	COG1797	cobyrinic acid a,c-diamide synthase activity
JDM601_3175	COG2329	Antibiotic biosynthesis monooxygenase
JDM601_3178	COG1492	cobalamin metabolic process
JDM601_3182	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JDM601_3183	COG1120	ATPase activity
JDM601_3189	COG2873	o-acetylhomoserine
JDM601_3195	COG1902	pentaerythritol trinitrate reductase activity
JDM601_3195	COG0446	pyridine nucleotide-disulphide oxidoreductase
JDM601_3196	COG1131	(ABC) transporter
JDM601_3196	COG1716	ATPase activity
JDM601_3196	COG0842	Transport permease protein
JDM601_3199	COG2018	Roadblock/LC7 domain
JDM601_3202	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JDM601_3205	COG0587	DNA-directed DNA polymerase activity
JDM601_3209	COG1877	trehalose-phosphatase activity
JDM601_3209	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JDM601_3210	COG1960	acyl-CoA dehydrogenase activity
JDM601_3213	COG0406	alpha-ribazole phosphatase activity
JDM601_3214	COG4221	oxidoreductase activity
JDM601_3218	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JDM601_3218	COG0519	Catalyzes the synthesis of GMP from XMP
JDM601_3222	COG0516	GMP reductase activity
JDM601_3238	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JDM601_3240	COG0456	acetyltransferase
JDM601_3240	COG1214	PFAM Peptidase M22, glycoprotease
JDM601_3245	COG0076	glutamate decarboxylase activity
JDM601_3249	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3251	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JDM601_3253	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_3259	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDM601_3262	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_3263	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
JDM601_3267	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JDM601_3269	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JDM601_3273	COG1674	ftsk spoiiie
JDM601_3275	COG1404	Belongs to the peptidase S8 family
JDM601_3278	COG0101	tRNA pseudouridine synthase activity
JDM601_3281	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JDM601_3282	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JDM601_3283	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JDM601_3287	COG1088	dTDP-glucose 4,6-dehydratase activity
JDM601_3292	COG1960	acyl-CoA dehydrogenase activity
JDM601_3296	COG2197	response regulator
JDM601_3303	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JDM601_3306	COG0616	signal peptide processing
JDM601_3307	COG5651	PPE family
JDM601_3309	COG0616	signal peptide processing
JDM601_3310	COG0616	signal peptide processing
JDM601_3313	COG0200	Binds to the 23S rRNA
JDM601_3315	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JDM601_3316	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JDM601_3318	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JDM601_3322	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JDM601_3323	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JDM601_3325	COG0583	DNA-binding transcription factor activity
JDM601_3330	COG0255	Belongs to the universal ribosomal protein uL29 family
JDM601_3331	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JDM601_3332	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JDM601_3333	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JDM601_3334	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JDM601_3335	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JDM601_3336	COG0089	rRNA binding
JDM601_3338	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JDM601_3341	COG2272	Belongs to the type-B carboxylesterase lipase family
JDM601_3343	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JDM601_3349	COG0535	radical SAM domain protein
JDM601_3356	COG2072	flavoprotein involved in K transport
JDM601_3357	COG4638	Rieske (2fe-2S)
JDM601_3359	COG1012	belongs to the aldehyde dehydrogenase family
JDM601_3364	COG2124	cytochrome p450
JDM601_3368	COG1088	dTDP-glucose 4,6-dehydratase activity
JDM601_3376	COG1960	acyl-CoA dehydrogenase activity
JDM601_3380	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3382	COG2337	Toxic component of a toxin-antitoxin (TA) module
JDM601_3386	COG1960	acyl-CoA dehydrogenase activity
JDM601_3387	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JDM601_3390	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_3392	COG1024	Enoyl-CoA hydratase
JDM601_3393	COG0300	oxidoreductase activity
JDM601_3394	COG1024	Enoyl-CoA hydratase
JDM601_3397	COG1024	Enoyl-CoA hydratase
JDM601_3399	COG1024	Enoyl-CoA hydratase
JDM601_3400	COG1024	Enoyl-CoA hydratase
JDM601_3401	COG1024	Enoyl-CoA hydratase
JDM601_3406	COG1802	Transcriptional regulator
JDM601_3408	COG1960	acyl-CoA dehydrogenase activity
JDM601_3409	COG0183	Belongs to the thiolase family
JDM601_3411	COG1960	acyl-CoA dehydrogenase activity
JDM601_3412	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3418	COG0714	Associated with various cellular activities
JDM601_3424	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_3426	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_3428	COG1024	Enoyl-CoA hydratase
JDM601_3431	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3433	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JDM601_3441	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3456	COG1053	succinate dehydrogenase
JDM601_3457	COG3384	dioxygenase
JDM601_3458	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JDM601_3459	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JDM601_3469	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JDM601_3480	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3481	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3484	COG1960	acyl-CoA dehydrogenase activity
JDM601_3485	COG1960	acyl-CoA dehydrogenase activity
JDM601_3491	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JDM601_3496	COG2124	cytochrome p450
JDM601_3503	COG4638	Rieske (2fe-2S)
JDM601_3507	COG1960	acyl-CoA dehydrogenase activity
JDM601_3508	COG1960	acyl-CoA dehydrogenase activity
JDM601_3509	COG1960	acyl-CoA dehydrogenase activity
JDM601_3511	COG1012	belongs to the aldehyde dehydrogenase family
JDM601_3512	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JDM601_3515	COG1960	acyl-CoA dehydrogenase activity
JDM601_3516	COG1960	acyl-CoA dehydrogenase activity
JDM601_3520	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3522	COG2072	flavoprotein involved in K transport
JDM601_3524	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3532	COG0581	inorganic phosphate transmembrane transporter activity
JDM601_3535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JDM601_3541	COG0745	RESPONSE REGULATOR receiver
JDM601_3545	COG2897	thiosulfate sulfurtransferase activity
JDM601_3547	COG4044	May play a role in the intracellular transport of hydrophobic ligands
JDM601_3549	COG0354	folic acid binding
JDM601_3552	COG1960	acyl-CoA dehydrogenase activity
JDM601_3553	COG1960	acyl-CoA dehydrogenase activity
JDM601_3557	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3560	COG0714	Associated with various cellular activities
JDM601_3571	COG2837	iron assimilation
JDM601_3574	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JDM601_3575	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JDM601_3578	COG4325	translation initiation factor activity
JDM601_3579	COG0386	Belongs to the glutathione peroxidase family
JDM601_3581	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JDM601_3587	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JDM601_3588	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JDM601_3589	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JDM601_3596	COG1024	Enoyl-CoA hydratase
JDM601_3600	COG1012	belongs to the aldehyde dehydrogenase family
JDM601_3603	COG4221	oxidoreductase activity
JDM601_3604	COG2124	cytochrome p450
JDM601_3609	COG2124	cytochrome p450
JDM601_3613	COG2205	protein histidine kinase activity
JDM601_3614	COG0745	RESPONSE REGULATOR receiver
JDM601_3619	COG1024	Enoyl-CoA hydratase
JDM601_3626	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JDM601_3631	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JDM601_3633	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3635	COG1960	acyl-CoA dehydrogenase activity
JDM601_3636	COG1960	acyl-CoA dehydrogenase activity
JDM601_3642	COG1132	(ABC) transporter
JDM601_3646	COG1012	belongs to the aldehyde dehydrogenase family
JDM601_3649	COG1024	Enoyl-CoA hydratase
JDM601_3652	COG2124	cytochrome p450
JDM601_3659	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDM601_3662	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JDM601_3668	COG4638	Rieske (2fe-2S)
JDM601_3675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDM601_3678	COG0514	ATP-dependent DNA helicase (RecQ)
JDM601_3679	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JDM601_3680	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JDM601_3683	COG1053	succinate dehydrogenase
JDM601_3689	COG2030	dehydratase
JDM601_3690	COG1960	acyl-CoA dehydrogenase activity
JDM601_3691	COG1960	acyl-CoA dehydrogenase activity
JDM601_3694	COG0183	Belongs to the thiolase family
JDM601_3702	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3703	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3704	COG1024	Enoyl-CoA hydratase
JDM601_3707	COG2070	2-Nitropropane dioxygenase
JDM601_3713	COG0183	Belongs to the thiolase family
JDM601_3715	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3716	COG1960	acyl-CoA dehydrogenase activity
JDM601_3717	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_3718	COG1960	acyl-CoA dehydrogenase activity
JDM601_3719	COG1960	acyl-CoA dehydrogenase activity
JDM601_3720	COG1960	acyl-CoA dehydrogenase activity
JDM601_3723	COG0436	Aminotransferase
JDM601_3730	COG4221	oxidoreductase activity
JDM601_3731	COG0300	oxidoreductase activity
JDM601_3734	COG2124	cytochrome p450
JDM601_3736	COG3246	L-lysine catabolic process to acetate
JDM601_3745	COG0183	Belongs to the thiolase family
JDM601_3750	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3751	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_3752	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JDM601_3754	COG1024	Enoyl-CoA hydratase
JDM601_3758	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JDM601_3758	COG0574	Belongs to the PEP-utilizing enzyme family
JDM601_3759	COG1960	acyl-CoA dehydrogenase activity
JDM601_3761	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JDM601_3764	COG1960	acyl-CoA dehydrogenase activity
JDM601_3767	COG1960	acyl-CoA dehydrogenase activity
JDM601_3768	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3769	COG2801	Transposase and inactivated derivatives
JDM601_3770	COG2963	transposase activity
JDM601_3777	COG1960	acyl-CoA dehydrogenase activity
JDM601_3778	COG1960	acyl-CoA dehydrogenase activity
JDM601_3786	COG1024	Enoyl-CoA hydratase
JDM601_3796	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JDM601_3804	COG2124	cytochrome p450
JDM601_3810	COG1960	acyl-CoA dehydrogenase activity
JDM601_3811	COG1960	acyl-CoA dehydrogenase activity
JDM601_3812	COG1024	Enoyl-CoA hydratase
JDM601_3813	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JDM601_3815	COG0574	Belongs to the PEP-utilizing enzyme family
JDM601_3816	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3824	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_3829	COG1960	acyl-CoA dehydrogenase activity
JDM601_3837	COG1024	Enoyl-CoA hydratase
JDM601_3840	COG1960	acyl-CoA dehydrogenase activity
JDM601_3843	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JDM601_3844	COG1960	acyl-CoA dehydrogenase activity
JDM601_3845	COG1024	Enoyl-CoA hydratase
JDM601_3846	COG2070	2-Nitropropane dioxygenase
JDM601_3863	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JDM601_3865	COG1960	acyl-CoA dehydrogenase activity
JDM601_3866	COG1309	transcriptional regulator
JDM601_3869	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JDM601_3870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JDM601_3875	COG1329	Transcriptional regulator
JDM601_3880	COG0288	reversible hydration of carbon dioxide
JDM601_3888	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JDM601_3889	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JDM601_3890	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JDM601_3891	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JDM601_3897	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JDM601_3898	COG0302	gtp cyclohydrolase
JDM601_3900	COG2267	carboxylic ester hydrolase activity
JDM601_3902	COG1063	alcohol dehydrogenase
JDM601_3907	COG0037	tRNA processing
JDM601_3909	COG2027	D-alanyl-D-alanine carboxypeptidase
JDM601_3927	COG0745	RESPONSE REGULATOR receiver
JDM601_3928	COG2205	protein histidine kinase activity
JDM601_3929	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JDM601_3933	COG1278	Cold shock
JDM601_3934	COG1205	dead DEAH box helicase
JDM601_3934	COG1111	helicase
JDM601_3945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JDM601_3951	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JDM601_3961	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JDM601_3962	COG1408	metallophosphoesterase
JDM601_3963	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JDM601_3965	COG3387	PFAM Glycoside hydrolase 15-related
JDM601_3971	COG0714	Associated with various cellular activities
JDM601_3972	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JDM601_3975	COG1695	Transcriptional regulator
JDM601_3977	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JDM601_3979	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JDM601_3983	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JDM601_3984	COG3572	ergothioneine biosynthetic process
JDM601_3986	COG1764	response to oxidative stress
JDM601_3993	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JDM601_3994	COG2176	DNA-directed DNA polymerase activity
JDM601_3995	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JDM601_3997	COG3835	regulator
JDM601_3998	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JDM601_4004	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JDM601_4005	COG0860	N-Acetylmuramoyl-L-alanine amidase
JDM601_4007	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JDM601_4009	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JDM601_4012	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JDM601_4023	COG1793	dna ligase
JDM601_4024	COG0596	Alpha beta hydrolase
JDM601_4030	COG0860	N-Acetylmuramoyl-L-alanine amidase
JDM601_4033	COG0590	tRNA wobble adenosine to inosine editing
JDM601_4036	COG0287	Prephenate dehydrogenase
JDM601_4037	COG5416	Lipopolysaccharide assembly protein A domain
JDM601_4041	COG2205	protein histidine kinase activity
JDM601_4042	COG0745	RESPONSE REGULATOR receiver
JDM601_4050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JDM601_4054	COG0861	Integral membrane protein TerC family
JDM601_4061	COG0583	DNA-binding transcription factor activity
JDM601_4071	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JDM601_4077	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_4082	COG1216	Glycosyl transferase, family 2
JDM601_4084	COG3609	addiction module antidote protein, CC2985 family
JDM601_4085	COG2337	Toxic component of a toxin-antitoxin (TA) module
JDM601_4086	COG4948	Mandelate Racemase Muconate Lactonizing
JDM601_4089	COG1487	ribonuclease activity
JDM601_4098	COG0277	FAD linked oxidase domain protein
JDM601_4099	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_4107	COG1845	cytochrome c oxidase, subunit III
JDM601_4110	COG0477	Major facilitator Superfamily
JDM601_4114	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JDM601_4115	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JDM601_4116	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JDM601_4118	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_4123	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JDM601_4124	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JDM601_4126	COG1216	Glycosyl transferase, family 2
JDM601_4130	COG0561	phosphatase activity
JDM601_4134	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JDM601_4134	COG2146	nitrite reductase [NAD(P)H] activity
JDM601_4142	COG1309	transcriptional regulator
JDM601_4143	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JDM601_4153	COG1316	TRANSCRIPTIONal
JDM601_4158	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JDM601_4160	COG2119	membrane
JDM601_4167	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JDM601_4168	COG2072	flavoprotein involved in K transport
JDM601_4171	COG2072	flavoprotein involved in K transport
JDM601_4172	COG1309	transcriptional regulator
JDM601_4176	COG0067	glutamate synthase
JDM601_4176	COG0069	glutamate synthase activity
JDM601_4176	COG0070	glutamate synthase
JDM601_4181	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JDM601_4184	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JDM601_4189	COG1022	Amp-dependent synthetase and ligase
JDM601_4189	COG3320	Male sterility
JDM601_4190	COG2755	lipolytic protein G-D-S-L family
JDM601_4190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JDM601_4192	COG2226	methyltransferase
JDM601_4197	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JDM601_4201	COG1012	belongs to the aldehyde dehydrogenase family
JDM601_4208	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JDM601_4210	COG0596	Alpha beta hydrolase
JDM601_4212	COG4638	Rieske (2fe-2S)
JDM601_4216	COG1309	transcriptional regulator
JDM601_4221	COG4689	acetoacetate decarboxylase
JDM601_4227	COG2030	dehydratase
JDM601_4232	COG4221	oxidoreductase activity
JDM601_4237	COG3757	hydrolase, family 25
JDM601_4239	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_4240	COG1012	belongs to the aldehyde dehydrogenase family
JDM601_4242	COG1946	Acyl-CoA thioesterase
JDM601_4244	COG1309	transcriptional regulator
JDM601_4247	COG2072	flavoprotein involved in K transport
JDM601_4250	COG0346	lactoylglutathione lyase activity
JDM601_4254	COG1902	pentaerythritol trinitrate reductase activity
JDM601_4254	COG0446	pyridine nucleotide-disulphide oxidoreductase
JDM601_4257	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_4258	COG2072	flavoprotein involved in K transport
JDM601_4259	COG0318	PFAM AMP-dependent synthetase and ligase
JDM601_4260	COG1063	alcohol dehydrogenase
JDM601_4262	COG1024	Enoyl-CoA hydratase
JDM601_4263	COG1960	acyl-CoA dehydrogenase activity
JDM601_4266	COG1028	Short-chain dehydrogenase reductase Sdr
JDM601_4271	COG1053	succinate dehydrogenase
JDM601_4274	COG1053	succinate dehydrogenase
JDM601_4281	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JDM601_4286	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JDM601_4287	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JDM601_4292	COG3757	hydrolase, family 25
JDM601_4293	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JDM601_4294	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JDM601_4300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JDM601_4301	COG0523	cobalamin synthesis protein
JDM601_4306	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JDM601_4307	COG0629	single-stranded DNA binding
JDM601_4308	COG0360	Binds together with S18 to 16S ribosomal RNA
JDM601_4310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JDM601_4311	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JDM601_4315	COG1260	myo-inositol-1-phosphate synthase
JDM601_4316	COG0596	Alpha beta hydrolase
JDM601_4317	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDM601_4318	COG0765	amino acid transport
JDM601_4321	COG0300	oxidoreductase activity
JDM601_4326	COG1678	Uncharacterized ACR, COG1678
JDM601_4327	COG2814	Major facilitator Superfamily
JDM601_4335	COG1595	DNA-templated transcription, initiation
JDM601_4340	COG3409	Peptidoglycan-binding domain 1 protein
JDM601_4340	COG0860	N-Acetylmuramoyl-L-alanine amidase
JDM601_4342	COG1192	Involved in chromosome partitioning
JDM601_4344	COG0706	membrane insertase activity
JDM601_4345	COG0594	ribonuclease P activity
JDM601_tRNA19	COG0544	peptidyl-prolyl cis-trans isomerase activity