locus-tag class description MDOR_00060 ENOG4105CHU acetyl-coa acetyltransferase MDOR_00090 ENOG4105CHU acetyl-coa acetyltransferase MDOR_00130 ENOG4107QX3 carboxylase MDOR_00140 ENOG41060WC Enoyl-CoA hydratase MDOR_00150 ENOG4108UKI Enoyl-CoA hydratase MDOR_00170 ENOG4105CEY Amp-dependent synthetase and ligase MDOR_00190 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone MDOR_00200 ENOG4105C1G acyl-Coa dehydrogenase MDOR_00210 ENOG4105EBR Carboxylesterase MDOR_00270 ENOG4105E5G Alpha beta hydrolase fold MDOR_00340 ENOG4105C01 Dihydroxy-acid dehydratase MDOR_00360 ENOG4105VPX protein, conserved in bacteria MDOR_00370 ENOG4105S7A ErfK ybiS ycfS ynhG family protein MDOR_00400 ENOG4105C7R Atpase associated with various cellular activities aaa_3 MDOR_00430 ENOG4105C9K Endothelin-converting enzyme 1 MDOR_00460 ENOG4105K4P CoA-binding domain protein MDOR_00480 ENOG4107WA4 MmpL domain-containing protein MDOR_00560 ENOG4107R13 MMPL domain protein MDOR_00620 ENOG4105FDP GntR family transcriptional regulator MDOR_00630 ENOG4105C1G acyl-Coa dehydrogenase MDOR_00730 ENOG4105X7H acyl-CoA dehydrogenase MDOR_00740 ENOG4108M6P methyltransferase MDOR_00770 ENOG41090MF Protein of unknown function (DUF3068) MDOR_00800 ENOG4107SFI Major Facilitator superfamily MDOR_00810 ENOG41073B4 coagulation factor 5 8 type domain-containing protein MDOR_00870 ENOG4105CHR reductase MDOR_00880 ENOG4105CHU acetyl-coa acetyltransferase MDOR_00890 ENOG4105CSU acyl-Coa dehydrogenase MDOR_00940 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) MDOR_00980 ENOG4107QZF nitrite reductase NADPH large subunit MDOR_01090 ENOG4108YV4 Universal stress protein MDOR_01110 ENOG4105MP0 transposase MDOR_01130 ENOG4105DQ6 Transposase MDOR_01190 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) MDOR_01230 ENOG4105C7N Xanthine uracil vitamin C permease MDOR_01240 ENOG4105ETU transcriptional activator (TenA MDOR_01280 ENOG4105CEY Amp-dependent synthetase and ligase MDOR_01290 ENOG4108KD5 ADP-ribosylation crystallin J1 MDOR_01320 ENOG4105D2B acyl-CoA dehydrogenase MDOR_01350 ENOG4105CA9 Pyruvate kinase MDOR_01440 ENOG4107QZ7 Cellulose synthase catalytic subunit MDOR_01450 ENOG4105WN5 stage II sporulation protein MDOR_01780 ENOG4105DF6 Fe-S oxidoreductase MDOR_01940 ENOG4108093 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ MDOR_01950 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) MDOR_01960 ENOG4105KNI merR family transcriptional Regulator MDOR_02050 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit MDOR_02110 ENOG4105D74 hydrolase MDOR_02130 ENOG4107QWG 2-Nitropropane dioxygenase MDOR_02140 ENOG4107XFB conserved TRANSMEMBRANE PROTEIN MDOR_02190 ENOG4107XZ0 Peptidase M50 MDOR_02210 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis MDOR_02310 ENOG4105E8R UPF0173 metal-dependent hydrolase MDOR_02320 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone MDOR_02340 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) MDOR_02350 ENOG4107Q25 Serine Threonine protein kinase MDOR_02360 ENOG4105CT1 (ABC) transporter MDOR_02420 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) MDOR_02430 ENOG4105IIU Aminopeptidase MDOR_02440 ENOG4105IIU Aminopeptidase MDOR_02460 ENOG4105C2W permease MDOR_02490 ENOG4107RN6 Monooxygenase MDOR_02520 ENOG4105DWF phosphomethylpyrimidine kinase MDOR_02610 ENOG4105H08 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) MDOR_02620 ENOG4106KXD ATP-dependent carboxylate-amine ligase (By similarity) MDOR_02800 ENOG4105KJM monovalent cation h antiporter subunit g MDOR_02810 ENOG410684G monovalent cation H antiporter subunit F MDOR_02830 ENOG4108JPZ Monovalent cation H antiporter subunit D MDOR_02840 ENOG4108ZE9 Monovalent cation H antiporter subunit C MDOR_02850 ENOG4105D65 subunit l MDOR_03020 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic MDOR_03050 ENOG4105C26 Dehydrogenase MDOR_03210 ENOG4106BRA Membrane MDOR_03230 ENOG4105V9F hemagglutinin MDOR_03320 ENOG4107R4N Cell wall formation (By similarity) MDOR_03390 ENOG4108YZJ Pfam:DUF2596 MDOR_03410 ENOG4105BZU Histidine kinase MDOR_03420 ENOG4105CK6 Two component transcriptional regulator (Winged helix family MDOR_03450 ENOG4107R33 ppx gppa phosphatase MDOR_03460 ENOG41063NU Membrane MDOR_03530 ENOG410900P UPF0336 protein MDOR_03640 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase MDOR_03650 ENOG4108RH7 phosphoglycerate mutase MDOR_03670 ENOG4107QIV Cytochrome c biogenesis protein MDOR_03690 ENOG4105CRE cytochrome C MDOR_03760 ENOG4107USC Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity) MDOR_03770 ENOG4105CMR udp-glucose 4-epimerase MDOR_03800 ENOG4105CK6 Two component transcriptional regulator (Winged helix family MDOR_03850 ENOG4105TMB Formate nitrite transporter MDOR_03860 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) MDOR_03910 ENOG4105PDP Short chain dehydrogenase MDOR_03920 ENOG4106F60 Histidine kinase MDOR_03930 ENOG4105F44 Two component transcriptional regulator, winged helix family MDOR_03980 ENOG4107SIQ Naphthoate synthase MDOR_03990 ENOG4105CI2 imidazolone-5-propionate hydrolase MDOR_04000 ENOG4107TCW O-succinylbenzoate synthase MDOR_04080 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) MDOR_04100 ENOG4105P52 geranylgeranyl reductase MDOR_04310 ENOG4105CHP RNA polymerase MDOR_04330 ENOG4105WH1 Two component transcriptional regulator luxr family MDOR_04430 ENOG4105CSR polyphosphate kinase 2 MDOR_04660 ENOG4108F3G Type I restriction-modification system, R subunit MDOR_04930 ENOG4105E7D Protein of unknown function (DUF3375) MDOR_04970 ENOG4105C0H protease MDOR_05050 ENOG4105CHH sulfate transporter MDOR_05060 ENOG4105C7H Helicase, RecD TraA family MDOR_05090 ENOG4107QKA exodeoxyribonuclease V beta MDOR_05100 ENOG4105DSY exodeoxyribonuclease V, gamma MDOR_05120 ENOG4105D7N magnesium and cobalt transport protein CorA MDOR_05130 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) MDOR_05150 ENOG4105WDJ 50S ribosomal protein L33 MDOR_05160 ENOG410900P UPF0336 protein MDOR_05170 ENOG4108F01 MaoC domain protein MDOR_05210 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) MDOR_05230 ENOG4105C6Y Udp-glucose 6-dehydrogenase MDOR_05240 ENOG4105C0D helicase MDOR_05260 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving MDOR_05270 ENOG4105E4E Thioester reductase domain-containing protein MDOR_05330 ENOG4107DZG Ribbon-helix-helix protein, copG family MDOR_05350 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) MDOR_05420 ENOG4105E2K Glycosyl transferase (Group 1 MDOR_05500 ENOG4105CFG Acts as a chaperone (By similarity) MDOR_05510 ENOG410827T Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ MDOR_05540 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit MDOR_05580 ENOG4107YJ4 chain length determinant protein MDOR_05610 ENOG4108KQJ Type 11 methyltransferase MDOR_05750 ENOG4105CMM transposase MDOR_05810 ENOG4108NUI synthase MDOR_05840 ENOG4105EXC Acyl-transferase MDOR_05870 ENOG4105MP0 transposase MDOR_05900 ENOG4105D70 Integrase catalytic subunit MDOR_06030 ENOG4108VZM 50s ribosomal protein L10 MDOR_06040 ENOG41082SK Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) MDOR_06120 ENOG4105CSU acyl-Coa dehydrogenase MDOR_06150 ENOG4105E39 Enoyl-CoA hydratase MDOR_06160 ENOG4105C0A alcohol dehydrogenase MDOR_06210 ENOG41068KF Universal stress protein MDOR_06270 ENOG4105XDV MDOR_06320 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) MDOR_06330 ENOG410633P Hydantoin racemase MDOR_06340 ENOG4105EBR Carboxylesterase MDOR_06450 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal MDOR_06460 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) MDOR_06470 ENOG4105E6M Sulphatase-modifying factor protein MDOR_06540 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) MDOR_06550 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) MDOR_06560 ENOG410849U 50S ribosomal protein L30 MDOR_06570 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) MDOR_06610 ENOG4106N8J Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity) MDOR_06620 ENOG4108XW1 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity) MDOR_06690 ENOG4105WH1 Two component transcriptional regulator luxr family MDOR_06720 ENOG4105C1G acyl-Coa dehydrogenase MDOR_06730 ENOG4105C26 Dehydrogenase MDOR_06740 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase MDOR_06750 ENOG4105C1B dTDP-glucose 4-6-dehydratase MDOR_06770 ENOG4105E2A Dehydrogenase MDOR_07020 ENOG410667J hydrolase MDOR_07100 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits MDOR_07190 ENOG41090GG peptidase S8 and S53, subtilisin, kexin, sedolisin MDOR_07210 ENOG4105EC2 ftsk spoIIIe MDOR_07250 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) MDOR_07310 ENOG4105DYW oxidoreductase MDOR_07330 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) MDOR_07350 ENOG4105CVK Glutamate decarboxylase MDOR_07360 ENOG4105CVK Glutamate decarboxylase MDOR_07370 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) MDOR_07380 ENOG4108EMS branched-chain alpha-keto acid dehydrogenase subunit E2 MDOR_07410 ENOG41080E2 ribosomal-protein-alanine acetyltransferase MDOR_07420 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) MDOR_07440 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) MDOR_07470 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein MDOR_07480 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) MDOR_07490 ENOG4105KIU Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) MDOR_07530 ENOG4108VT4 MDOR_07550 ENOG4107QVP Dehydrogenase MDOR_07590 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) MDOR_07610 ENOG4107RN6 Monooxygenase MDOR_07660 ENOG41090MY MarR family Transcriptional regulator MDOR_07680 ENOG4105C0B DNA polymerase III (alpha subunit) MDOR_07700 ENOG4105D7V transposase MDOR_07720 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) MDOR_07740 ENOG4105BZU Histidine kinase MDOR_07750 ENOG4105GWZ Roadblock lc7 family protein MDOR_07810 ENOG4105IDI abc transporter atp-binding protein MDOR_07860 ENOG4108UXE Protein tyrosine phosphatase MDOR_07960 ENOG4108IQK o-acetylhomoserine MDOR_07970 ENOG4105E9K Isocitrate dehydrogenase MDOR_08000 ENOG4107H3J ribonuclease MDOR_08010 ENOG4105MZU cell filamentation protein MDOR_08050 ENOG4105DZ1 carboxypeptidase MDOR_08070 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) MDOR_08080 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) MDOR_08180 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) MDOR_08240 ENOG4107QSU Phosphoglucomutase phosphomannomutase alpha beta alpha domain MDOR_08270 ENOG4107RM1 amidohydrolase MDOR_08310 ENOG4105D3G Pseudouridine synthase MDOR_08370 ENOG4105D5T phosphonate abc transporter MDOR_08380 ENOG4105S7S phosphonate abc transporter MDOR_08440 ENOG4105ENV phosphonate C-P lyase system protein PhnK MDOR_08450 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) MDOR_08510 ENOG4108IUE nitrate reductase beta subunit MDOR_08550 ENOG4107QRT dEAD DEAH box helicase MDOR_08560 ENOG41061TZ Short-chain dehydrogenase reductase Sdr MDOR_08580 ENOG4105C26 Dehydrogenase MDOR_08660 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) MDOR_08700 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase MDOR_08710 ENOG4105DKP glycosyl transferase, family 9 MDOR_08720 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) MDOR_08730 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) MDOR_08740 ENOG4108R85 Short chain dehydrogenase MDOR_08830 ENOG41080U6 GntR family transcriptional regulator MDOR_08860 ENOG4108JIK carboxylase MDOR_08920 ENOG4105D8K carboxyl transferase MDOR_08930 ENOG4105D3Q Sugar transferase MDOR_08970 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) MDOR_08990 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase MDOR_09010 ENOG4107TB5 TRANSCRIPTIONal MDOR_09020 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase MDOR_09060 ENOG41088YA Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity) MDOR_09080 ENOG4105K51 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) MDOR_09130 ENOG4105EIP mannose-6-phosphate isomerase MDOR_09150 ENOG4105CUB amino acid MDOR_09160 ENOG4105VCQ rubredoxin MDOR_09180 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) MDOR_09260 ENOG4105CK6 Two component transcriptional regulator (Winged helix family MDOR_09270 ENOG4105BZU Histidine kinase MDOR_09300 ENOG4108S7Q sigma 54 modulation protein ribosomal protein S30ea MDOR_09380 ENOG4105CV8 reductase MDOR_09430 ENOG4105EMN RNA polymerase sigma factor MDOR_09440 ENOG4105WMN AntiSigma factor MDOR_09460 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit MDOR_09500 ENOG4107TE5 Lipid kinase MDOR_09540 ENOG4108ZM9 phosphoglycerate mutase MDOR_09660 ENOG4108YIQ Alpha beta hydrolase MDOR_09720 ENOG4107QRI Phosphoketolase MDOR_09840 ENOG4105CQS hydrogenase expression formation protein HypD MDOR_09870 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) MDOR_09880 ENOG4107RSS Hydrogenase accessory protein HypB MDOR_09910 ENOG4105WBQ Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) MDOR_09920 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) MDOR_09950 ENOG41063PX domain protein MDOR_09960 ENOG4105DJZ UPF0182 protein MDOR_09990 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) MDOR_10000 ENOG4106F59 XRE family Transcriptional regulator MDOR_10010 ENOG4105XUP Phage derived protein Gp49-like (DUF891) MDOR_10020 ENOG4105VTR Integrase MDOR_10420 ENOG4106IJN integrase catalytic domain-containing protein MDOR_10430 ENOG4105F5W AtP-binding protein MDOR_10490 ENOG41082SX arsR family transcriptional regulator MDOR_10510 ENOG4105MKU Transcriptional regulator MDOR_10540 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) MDOR_10570 ENOG4105CQB FAD linked oxidase domain protein MDOR_10610 ENOG4105CT3 Monooxygenase MDOR_10620 ENOG4105E39 Enoyl-CoA hydratase MDOR_10630 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) MDOR_10660 ENOG4105M5H NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) MDOR_10670 ENOG4105DF2 NADH dehydrogenase subunit j MDOR_10680 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) MDOR_10700 ENOG4108IEH NADH dehydrogenase subunit g MDOR_10750 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) MDOR_10780 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase MDOR_10790 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F MDOR_10810 ENOG4105C1G acyl-Coa dehydrogenase MDOR_10830 ENOG4107TK4 histidinol-phosphate phosphatase MDOR_10890 ENOG4105CAK Cell division ATP-binding protein ftsE MDOR_10900 ENOG4107RYD Part of the ABC transporter FtsEX involved in cellular division (By similarity) MDOR_10930 ENOG4105CT3 Monooxygenase MDOR_10940 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) MDOR_10950 ENOG4106839 domain protein MDOR_10980 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) MDOR_11030 ENOG4105MWK D-amino acid dehydrogenase, small subunit MDOR_11030 ENOG4105MWK D-amino acid dehydrogenase, small subunit MDOR_11040 ENOG41080U6 GntR family transcriptional regulator MDOR_11100 ENOG4108ISG Major Facilitator MDOR_11250 ENOG4108Z6K Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity) MDOR_11310 ENOG4107Y2X deaminase MDOR_11320 ENOG4105KPY Small multidrug resistance protein MDOR_11350 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) MDOR_11370 ENOG4108ZUB Lysine exporter protein (Lyse ygga) MDOR_11410 ENOG4105EKQ RNA-directed DNA polymerase MDOR_11440 ENOG4105DQ6 Transposase MDOR_11460 ENOG4105MP0 transposase MDOR_11480 ENOG4105CMM transposase MDOR_11500 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) MDOR_11660 ENOG4105MP0 transposase MDOR_11670 ENOG4105F5W AtP-binding protein MDOR_11680 ENOG4106IJN integrase catalytic domain-containing protein MDOR_11730 ENOG4107R3N Filamentation induced by cAMP protein fic MDOR_11750 ENOG4105D3R alkyl hydroperoxide reductase MDOR_11790 ENOG4107UBC ErfK ybiS ycfS ynhG family protein MDOR_11800 ENOG4107TPS domain protein MDOR_11840 ENOG4105FDP GntR family transcriptional regulator MDOR_11860 ENOG4105F5W AtP-binding protein MDOR_11870 ENOG4105D70 Integrase catalytic subunit MDOR_11880 ENOG4105MP0 transposase MDOR_11900 ENOG4105DQ6 Transposase MDOR_11940 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) MDOR_11950 ENOG4107QIV Cytochrome c biogenesis protein MDOR_11990 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) MDOR_12070 ENOG4105C1G acyl-Coa dehydrogenase MDOR_12090 ENOG4105CHU acetyl-coa acetyltransferase MDOR_12100 ENOG4105C1G acyl-Coa dehydrogenase MDOR_12110 ENOG4108WYP Transcriptional regulator MDOR_12200 ENOG41061TZ Short-chain dehydrogenase reductase Sdr MDOR_12270 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) MDOR_12310 ENOG4105EJ2 Transcriptional regulator MDOR_12340 ENOG4105DQ4 alcohol dehydrogenase MDOR_12380 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase MDOR_12400 ENOG4108RZE Tetr family transcriptional regulator MDOR_12420 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component MDOR_12430 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component MDOR_12530 ENOG4105EAC phosphoserine phosphatase MDOR_12540 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family MDOR_12550 ENOG4105DKW ABC transporter MDOR_12610 ENOG4108V0V Pyrrolo-quinoline quinone MDOR_12620 ENOG4105EVB acetyltransferase MDOR_12650 ENOG4108KQJ Type 11 methyltransferase MDOR_12670 ENOG4105C10 Electron transfer flavoprotein MDOR_12750 ENOG4105CEY Amp-dependent synthetase and ligase MDOR_12780 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) MDOR_12870 ENOG41081AP Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) MDOR_12900 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) MDOR_12910 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) MDOR_12960 ENOG4108ZP8 Acetolactate synthase small subunit MDOR_13020 ENOG4105WEF catalase MDOR_13040 ENOG4105E5T Major Facilitator Superfamily MDOR_13050 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase MDOR_13080 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) MDOR_13120 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) MDOR_13150 ENOG4105C28 cystathionine MDOR_13220 ENOG4105DP4 dak2 domain fusion protein ylov MDOR_13230 ENOG4105CB5 ATP-dependent DNA helicase recG MDOR_13250 ENOG4105CV8 reductase MDOR_13310 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) MDOR_13320 ENOG4106H78 methyltransferase MDOR_13350 ENOG41087HT growth MDOR_13370 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) MDOR_13420 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) MDOR_13460 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) MDOR_13560 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) MDOR_13660 ENOG4105D7V transposase MDOR_13680 ENOG4105IYB L-carnitine dehydratase bile acid-inducible protein F MDOR_13700 ENOG4105CEY Amp-dependent synthetase and ligase MDOR_13710 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) MDOR_13790 ENOG4105DMF Dehydrogenase MDOR_13800 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) MDOR_13870 ENOG4105MP0 transposase MDOR_13890 ENOG4105DQ6 Transposase MDOR_13920 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) MDOR_13950 ENOG4105BZW Glycerate kinase MDOR_14020 ENOG4105CVP deoxyribo-dipyrimidine photolyase MDOR_14070 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) MDOR_14080 ENOG4105DZP Membrane-associated zinc metalloprotease MDOR_14180 ENOG4105CAQ asparagine synthetase MDOR_14200 ENOG4105C5F glutamine synthetase MDOR_14210 ENOG4108Z86 Glutamine amidotransferase MDOR_14220 ENOG4105C26 Dehydrogenase MDOR_14230 ENOG4105H9W Short-chain dehydrogenase reductase Sdr MDOR_14300 ENOG4108JJB ABC transporter MDOR_14360 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase MDOR_14380 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) MDOR_14470 ENOG4105SFS phosphoesterase RecJ domain protein MDOR_14490 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) MDOR_14600 ENOG4105K5B UPF0225 protein MDOR_14610 ENOG4105DCF alanine dehydrogenase MDOR_14710 ENOG4105T0Z Conserved Protein MDOR_14730 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) MDOR_14740 ENOG4105CN5 Metallo-Beta-Lactamase MDOR_14790 ENOG4108I62 cina-like protein MDOR_14800 ENOG4105WBV Transcriptional regulator MDOR_14830 ENOG4105MXB limonene-12-epoxide hydrolase MDOR_14890 ENOG4105CQS hydrogenase expression formation protein HypD MDOR_14920 ENOG4105WRB Hydrogenase assembly chaperone hypC hupF MDOR_14990 ENOG4105DPX Hydrogenase, large subunit MDOR_15020 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) MDOR_15090 ENOG4105DRP amino acid AbC transporter MDOR_15100 ENOG4108Q1T ABC transporter MDOR_15110 ENOG4107UBR Extracellular solute-binding protein family 3 MDOR_15120 ENOG4105CDA abc transporter atp-binding protein MDOR_15150 ENOG4105C99 atpase involved in dna repair MDOR_15170 ENOG4105PP6 Membrane MDOR_15210 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) MDOR_15220 ENOG4105C1J atp-dependent rna helicase MDOR_15550 ENOG4107VEG TrkA-N domain protein MDOR_15560 ENOG4105C0X amino acid MDOR_15570 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) MDOR_15580 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) MDOR_15610 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) MDOR_15650 ENOG4107JTW chlorite dismutase MDOR_15660 ENOG4105E0X reductase MDOR_15670 ENOG4108P2G integral membrane protein MDOR_15720 ENOG4105K6V RNA polymerase MDOR_15790 ENOG4105PMW Domain of unknown function (DUF1990) MDOR_15850 ENOG4107YQ3 lipid a biosynthesis lauroyl acyltransferase MDOR_15860 ENOG4105E2K Glycosyl transferase (Group 1 MDOR_15870 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) MDOR_15880 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) MDOR_15890 ENOG4105C29 acyl-CoA thioesterase MDOR_15940 ENOG4107SCA Formamidase (EC 3.5.1.49) MDOR_16020 ENOG4107RTU Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) MDOR_16030 ENOG4108NY6 Extracellular solute-binding protein, family 5 MDOR_16050 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) MDOR_16080 ENOG4107VMB Beta-lactamase domain protein MDOR_16090 ENOG4107R36 histidyl-tRNA synthetase MDOR_16100 ENOG4108IV0 ABC, transporter MDOR_16110 ENOG4105C0Z ABC transporter MDOR_16130 ENOG4105C32 Amino acid ABC transporter (Permease) MDOR_16160 ENOG4105VEQ Cold shock protein MDOR_16200 ENOG4105EBR Carboxylesterase MDOR_16230 ENOG4105C9M aspartyl-trna synthetase MDOR_16320 ENOG4107ZED Uncharacterised protein family UPF0047 MDOR_16410 ENOG4105D49 3-dehydroquinate synthase MDOR_16440 ENOG4105DC7 peptidase M24 MDOR_16450 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) MDOR_16480 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) MDOR_16490 ENOG4105CXT aspartate transcarbamylase MDOR_16520 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain MDOR_16550 ENOG4108RS6 transposase MDOR_16560 ENOG4105D7V transposase MDOR_16590 ENOG4105MTQ Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) MDOR_16630 ENOG4107SCA Formamidase (EC 3.5.1.49) MDOR_16690 ENOG4107UWP Major facilitator superfamily MFS_1 MDOR_16700 ENOG41064B9 (LipO)protein MDOR_16720 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) MDOR_16750 ENOG4105K5X acetyltransferase MDOR_16820 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase MDOR_16840 ENOG4105CP7 Triose-phosphate isomerase MDOR_16870 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) MDOR_16920 ENOG4107QQX Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) MDOR_16950 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein MDOR_17010 ENOG4107JC6 Membrane MDOR_17050 ENOG4105C3K feS assembly ATPase SufC MDOR_17070 ENOG4108UNV SUF system FeS assembly protein, NifU family MDOR_17080 ENOG4105VG1 fes assembly suf system protein MDOR_17100 ENOG4105EKQ RNA-directed DNA polymerase MDOR_17150 ENOG41080RH Thioredoxin MDOR_17160 ENOG4105C5H ABC transporter MDOR_17170 ENOG4108Q5F Tetr family transcriptional regulator MDOR_17180 ENOG4107QM5 aconitate hydratase MDOR_17210 ENOG4105ZXU NLP P60 protein MDOR_17230 ENOG4105C7R Atpase associated with various cellular activities aaa_3 MDOR_17260 ENOG4105CHR reductase MDOR_17270 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH MDOR_17280 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) MDOR_17350 ENOG4107TMB Transcriptional regulator MDOR_17430 ENOG4108RG3 short-chain dehydrogenase reductase MDOR_17500 ENOG4105CTK cobaltochelatase, cobn subunit MDOR_17530 ENOG4105CI2 imidazolone-5-propionate hydrolase MDOR_17540 ENOG4107R05 Transfers the fatty acyl group on membrane lipoproteins (By similarity) MDOR_17550 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) MDOR_17560 ENOG4105Q70 MDOR_17580 ENOG4105C9U ATP-dependent DNA helicase RecQ MDOR_17740 ENOG41086VY Fic/DOC family MDOR_17750 ENOG4105C0I Conserved Protein MDOR_17760 ENOG4105CAQ asparagine synthetase MDOR_17780 ENOG4105F5W AtP-binding protein MDOR_17810 ENOG4106IJN integrase catalytic domain-containing protein MDOR_17840 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) MDOR_17880 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component MDOR_17890 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component MDOR_17940 ENOG4105DEF Extracellular solute-binding protein, family 5 MDOR_17990 ENOG4105WH1 Two component transcriptional regulator luxr family MDOR_18000 ENOG4105DEF Extracellular solute-binding protein, family 5 MDOR_18010 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component MDOR_18020 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component MDOR_18030 ENOG4105C3U ABC transporter MDOR_18050 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) MDOR_18080 ENOG4105P8G Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity) MDOR_18090 ENOG4107YEM Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) MDOR_18100 ENOG4108YZ9 Urea amidohydrolase subunit gamma MDOR_18110 ENOG4105CQM Urea amidohydrolase subunit alpha MDOR_18120 ENOG4105CM9 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) MDOR_18130 ENOG4108EI5 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) MDOR_18140 ENOG410684T prevent-host-death family MDOR_18150 ENOG4105VG9 Plasmid stabilization system MDOR_18380 ENOG4105D3R alkyl hydroperoxide reductase MDOR_18390 ENOG4107TPS domain protein MDOR_18410 ENOG4105XTG Pfam:DUF156 MDOR_18420 ENOG4108IFH alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MDOR_18440 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) MDOR_18480 ENOG4107QIV Cytochrome c biogenesis protein MDOR_18540 ENOG41082BM Transcriptional regulator, arsr family MDOR_18620 ENOG4105MP0 transposase MDOR_18630 ENOG4105DQ6 Transposase MDOR_18700 ENOG4107UBC ErfK ybiS ycfS ynhG family protein MDOR_18740 ENOG4105CCU oxidase (Subunit III) MDOR_18830 ENOG4105BZ9 Cytochrome C oxidase, subunit I MDOR_18850 ENOG4105CRE cytochrome C MDOR_18870 ENOG4105C59 p-type ATPase MDOR_18890 ENOG4105S7A ErfK ybiS ycfS ynhG family protein MDOR_18910 ENOG4107QIV Cytochrome c biogenesis protein MDOR_18930 ENOG4105E4J Cytochrome c oxidase caa3-type, assembly factor ctag-related protein MDOR_19030 ENOG4105EB3 Histidine kinase MDOR_19040 ENOG4105CK6 Two component transcriptional regulator (Winged helix family MDOR_19060 ENOG4105ZXU NLP P60 protein MDOR_19090 ENOG4105DPZ Two component transcriptional regulator (Winged helix family MDOR_19110 ENOG4107UBC ErfK ybiS ycfS ynhG family protein MDOR_19170 ENOG4105VPX protein, conserved in bacteria MDOR_19210 ENOG4105DQ6 Transposase MDOR_19240 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) MDOR_19350 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) MDOR_19490 ENOG4105C0D helicase MDOR_19640 ENOG4105C0D helicase MDOR_19670 ENOG4105ESI atpase involved in dna repair MDOR_19700 ENOG4105NFY transcriptional modulator of maze toxin, mazf MDOR_19710 ENOG4106FC9 Protein of unknown function (DUF3018) MDOR_19760 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) MDOR_19870 ENOG4108V1T peptidylprolyl cis-trans isomerase MDOR_19890 ENOG4105CKW Inner membrane protein yedI MDOR_19900 ENOG4105ZXU NLP P60 protein MDOR_19930 ENOG4105C26 Dehydrogenase MDOR_20020 ENOG4108RQS Two component transcriptional regulator (Winged helix family MDOR_20030 ENOG4105BZU Histidine kinase MDOR_20060 ENOG4107XFJ UPF0246 protein MDOR_20110 ENOG4105WYW fructose-bisphosphate aldolase MDOR_20260 ENOG4105FF0 ErfK YbiS YcfS YnhG MDOR_20270 ENOG4105C7B Threonine dehydratase MDOR_20340 ENOG4108MJN Glycosyl Transferase MDOR_20370 ENOG4105C5F glutamine synthetase MDOR_20390 ENOG4108UQY Iron-storage protein MDOR_20440 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) MDOR_20500 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) MDOR_20540 ENOG4107QRI Phosphoketolase MDOR_20610 ENOG4105CEP NADH dehydrogenase MDOR_20620 ENOG4105MT3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) MDOR_20720 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) MDOR_20740 ENOG4105C37 (CBS) domain MDOR_20750 ENOG4107UAX integral membrane protein MDOR_20800 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor MDOR_20840 ENOG4108UW8 fha domain-containing protein MDOR_20940 ENOG4105CKD glutathione-regulated potassium-efflux system protein MDOR_20960 ENOG4105EBR Carboxylesterase MDOR_20980 ENOG410814C multidrug resistance protein MDOR_21020 ENOG4105EMU Dehydrogenase MDOR_21060 ENOG4107R7Y intracellular protease Pfpi family MDOR_21120 ENOG4107R6F Alpha Beta Hydrolase Fold protein MDOR_21230 ENOG4107TPY serine threonine protein kinase MDOR_21250 ENOG41073TP transcriptional regulator MDOR_21260 ENOG4105C5A transporter MDOR_21270 ENOG4105P4J Allophanate hydrolase, subunit 1 MDOR_21290 ENOG4105CFM UPF0317 protein MDOR_21390 ENOG410635A Membrane MDOR_21400 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) MDOR_21430 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) MDOR_21490 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) MDOR_21520 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) MDOR_21560 ENOG4105DSU hydrolase MDOR_21600 ENOG4105W49 UPF0434 protein MDOR_21630 ENOG4105C5H ABC transporter MDOR_21660 ENOG4105CDH Citrulline--aspartate ligase MDOR_21680 ENOG4105DBV ornithine carbamoyltransferase MDOR_21690 ENOG4105C8Y Acetylornithine aminotransferase MDOR_21700 ENOG4105CAS nag kinase MDOR_21710 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) MDOR_21730 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) MDOR_21740 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) MDOR_21760 ENOG4105C1G acyl-Coa dehydrogenase MDOR_21820 ENOG4105CRK lysyL-tRNA synthetase MDOR_21850 ENOG4105C5X domain protein MDOR_21890 ENOG4108TAG Histidine kinase MDOR_22030 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) MDOR_22040 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) MDOR_22100 ENOG4108IV0 ABC, transporter MDOR_22110 ENOG4105C0Z ABC transporter MDOR_22120 ENOG4105CF8 branched-chain amino acid ABC transporter, permease MDOR_22130 ENOG4105C32 Amino acid ABC transporter (Permease) MDOR_22160 ENOG4105CYX Short-chain dehydrogenase reductase Sdr MDOR_22200 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction MDOR_22210 ENOG4105CDA abc transporter atp-binding protein MDOR_22230 ENOG4105EAB amino acid AbC transporter MDOR_22260 ENOG4105C29 acyl-CoA thioesterase MDOR_22290 ENOG4105CBC glutamate synthase MDOR_22370 ENOG4105CRQ synthase (Component I) MDOR_22380 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase MDOR_22400 ENOG4108MWI inositol mono-phosphatase MDOR_22420 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) MDOR_22450 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) MDOR_22480 ENOG4107S3R L-aspartate oxidase MDOR_22600 ENOG4107QNE Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) MDOR_22720 ENOG4107ZIW This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) MDOR_22730 ENOG4105HDK L-asparaginase MDOR_22750 ENOG410848D S4 domain protein YaaA MDOR_22760 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) MDOR_22890 ENOG4105C6Y Udp-glucose 6-dehydrogenase MDOR_22900 ENOG4105C6Y Udp-glucose 6-dehydrogenase MDOR_23120 ENOG4105E5F proteasome MDOR_23250 ENOG4105C3R Methionine synthase MDOR_23340 ENOG4108RM3 Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I- 1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F- 6-P)) and AMP in vitro, but this might has no significance in vivo MDOR_23440 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) MDOR_23490 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) MDOR_23500 ENOG4105DQQ Major facilitator superfamily MFS_1 MDOR_23520 ENOG4108IFG nitrite reductase, (NAD(P)H) MDOR_23530 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit MDOR_23560 ENOG4105D7V transposase MDOR_23580 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) MDOR_23690 ENOG4105ME9 cell division protein FtsQ MDOR_23730 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) MDOR_23740 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) MDOR_23770 ENOG4105CJN penicillin-binding protein MDOR_23830 ENOG4105R14 (LipO)protein MDOR_23850 ENOG41090CE integral membrane protein MDOR_23860 ENOG4105KYH transcriptional regulatory protein MDOR_23880 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase MDOR_23910 ENOG4108VJY integral membrane protein MDOR_23980 ENOG4105JNK Glycosyl transferase (Group 1 MDOR_24030 ENOG4105CCU oxidase (Subunit III) MDOR_24120 ENOG4107T4Z adenosine kinase MDOR_24190 ENOG4105CM2 brancheD-chain amino acid aminotransferase MDOR_24310 ENOG4105C5F glutamine synthetase MDOR_24340 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) MDOR_24350 ENOG4105C5F glutamine synthetase MDOR_24400 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) MDOR_24410 ENOG4105C3M thioredoxin reductase MDOR_24500 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) MDOR_24790 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase MDOR_24800 ENOG41082KT Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) MDOR_24810 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) MDOR_24910 ENOG4105C5X domain protein MDOR_24930 ENOG4105DEF Extracellular solute-binding protein, family 5 MDOR_24950 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component MDOR_24960 ENOG4108JQ6 ABC transporter MDOR_25220 ENOG4107Z7P Ferredoxin MDOR_25410 ENOG4105DXB Major Facilitator superfamily MDOR_25430 ENOG4105C1G acyl-Coa dehydrogenase MDOR_25470 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) MDOR_25480 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein MDOR_25500 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) MDOR_25540 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) MDOR_25640 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) MDOR_25720 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein MDOR_25740 ENOG4105BZP glycoside hydrolase 15-related MDOR_25780 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) MDOR_25790 ENOG4105C8S subunit m MDOR_25830 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) MDOR_25940 ENOG4105KQC Competence protein MDOR_25970 ENOG4108TZC MDOR_25980 ENOG4105CVJ phosphoglycerate mutase MDOR_25990 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) MDOR_26020 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit MDOR_26040 ENOG4108RVA ribokinase MDOR_26100 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) MDOR_26140 ENOG4105C03 ribonuclease MDOR_26170 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase MDOR_26180 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) MDOR_26190 ENOG4105EG6 Saccharopine dehydrogenase MDOR_26200 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein MDOR_26240 ENOG41080AZ Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) MDOR_26250 ENOG4105DQU oxidoreductase, subunit beta MDOR_26260 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein MDOR_26280 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) MDOR_26310 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) MDOR_26360 ENOG4108J2R molybdopterin oxidoreductase MDOR_26410 ENOG4108IQE Amp-dependent synthetase and ligase MDOR_26420 ENOG4105MC2 DSBA oxidoreductase MDOR_26450 ENOG4109057 MDOR_26490 ENOG4105CG3 alpha amylase, catalytic region MDOR_26520 ENOG4105C7I Dehydrogenase MDOR_26650 ENOG4105MP0 transposase MDOR_26670 ENOG4107RN0 branched-chain alpha-keto acid dehydrogenase subunit E2 MDOR_26710 ENOG4105DJG MaoC domain protein dehydratase MDOR_26720 ENOG4105C1G acyl-Coa dehydrogenase MDOR_26740 ENOG4107QX3 carboxylase MDOR_26770 ENOG4105PDP Short chain dehydrogenase MDOR_26830 ENOG4107FW0 short-chain dehydrogenase reductase MDOR_26850 ENOG4107UBC ErfK ybiS ycfS ynhG family protein MDOR_26880 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) MDOR_26930 ENOG4105DJB Major Facilitator Superfamily MDOR_26960 ENOG4105CHU acetyl-coa acetyltransferase MDOR_27020 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) MDOR_27040 ENOG4108RQ5 Beta-lactamase domain-containing protein MDOR_27050 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) MDOR_27130 ENOG4107RKP Nicotinate phosphoribosyltransferase MDOR_27160 ENOG4108IUN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) MDOR_27170 ENOG4105EP6 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity) MDOR_27180 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) MDOR_27200 ENOG4105EYF MMPL domain protein MDOR_27210 ENOG4105CHU acetyl-coa acetyltransferase MDOR_27240 ENOG4105CYV Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity) MDOR_27260 ENOG4107RCI amp-dependent synthetase and ligase MDOR_27270 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) MDOR_27390 ENOG4107RAZ it plays a direct role in the translocation of protons across the membrane (By similarity) MDOR_27410 ENOG4105ESV Glycosyl transferase, family 4 MDOR_27430 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) MDOR_27470 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) MDOR_27480 ENOG4107R5I Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) MDOR_27490 ENOG4105D6E homoserine dehydrogenase MDOR_27500 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) MDOR_27540 ENOG4105CSH Transporter MDOR_27560 ENOG4108RM3 Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I- 1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F- 6-P)) and AMP in vitro, but this might has no significance in vivo MDOR_27600 ENOG4105MP0 transposase MDOR_27630 ENOG4105DQ6 Transposase MDOR_27640 ENOG4105BZU Histidine kinase MDOR_27650 ENOG4105CK6 Two component transcriptional regulator (Winged helix family MDOR_27780 ENOG410681U heavy metal transport detoxification protein MDOR_27820 ENOG4105DEN Luciferase family MDOR_27860 ENOG4105CQB FAD linked oxidase domain protein MDOR_27890 ENOG41072EW lipoprotein LprE MDOR_27920 ENOG4105C2C drug resistance transporter, Bcr CflA MDOR_27940 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 MDOR_27970 ENOG4105D7N magnesium and cobalt transport protein CorA MDOR_28060 ENOG4105CJW magnesium transporter MDOR_28110 ENOG4105C0H protease MDOR_28120 ENOG4106684 MDOR_28130 ENOG4105DU6 RNA polymerase MDOR_28170 ENOG4107QPH glycogen) synthase MDOR_28190 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) MDOR_28210 ENOG4105C3Q Glycosyl transferase, family 2 MDOR_28260 ENOG4107R4C succinyl-diaminopimelate desuccinylase MDOR_28280 ENOG4105XTG Pfam:DUF156 MDOR_28300 ENOG4105CEY Amp-dependent synthetase and ligase MDOR_28360 ENOG4108Z4U Ferredoxin MDOR_28370 ENOG4105DKF Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity) MDOR_28390 ENOG4108KZ5 Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity) MDOR_28430 ENOG4107USK Extracellular solute-binding protein, family 5 MDOR_28440 ENOG4105CI3 gtp-binding protein typa MDOR_28460 ENOG410842T Pterin carbinolamine dehydratase MDOR_28470 ENOG4108U8T Mannosyltransferase MDOR_28530 ENOG4107QN1 sodium solute MDOR_28570 ENOG410905P Pyridoxamine 5-phosphate MDOR_28640 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) MDOR_28680 ENOG410846T CoA-transferase family III MDOR_28690 ENOG4108UKI Enoyl-CoA hydratase MDOR_28710 ENOG4105CGD Nad-dependent epimerase dehydratase MDOR_28720 ENOG4108Z0R Transferase MDOR_28740 ENOG4105C1G acyl-Coa dehydrogenase MDOR_28760 ENOG4105CHU acetyl-coa acetyltransferase MDOR_28770 ENOG4107YCY Transcriptional regulator MDOR_28850 ENOG4105C3G gtp-binding protein MDOR_29000 ENOG4108IAB Phoh family MDOR_29020 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) MDOR_29050 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) MDOR_29070 ENOG4105C7Z Conserved Protein MDOR_29090 ENOG4105T1M mycothiol conjugate amidase mca MDOR_29110 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) MDOR_29140 ENOG4105C1G acyl-Coa dehydrogenase MDOR_29190 ENOG4105CHU acetyl-coa acetyltransferase MDOR_29210 ENOG4105E39 Enoyl-CoA hydratase MDOR_29360 ENOG4105CMQ Chloride channel MDOR_29430 ENOG4107Z7P Ferredoxin MDOR_29460 ENOG4105BZU Histidine kinase MDOR_29470 ENOG4108VB1 regulatoR MDOR_29590 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) MDOR_29810 ENOG410650H (LipO)protein MDOR_29820 ENOG4105DBE peroxidase MDOR_29830 ENOG4105DXN mazG family MDOR_29850 ENOG4108IG5 Transcriptional regulator MDOR_29910 ENOG4107XT7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) MDOR_29940 ENOG4107RCI amp-dependent synthetase and ligase MDOR_29950 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) MDOR_29970 ENOG4106839 domain protein MDOR_29980 ENOG4105F8V Hydrolase, tatD family MDOR_30000 ENOG4107R37 Glutamate dehydrogenase MDOR_30060 ENOG4105CEU Arginine dihydrolase MDOR_30070 ENOG4108Z4X TRANSCRIPTIONal MDOR_30120 ENOG410870F Cyclic nucleotide-binding protein MDOR_30130 ENOG410870F Cyclic nucleotide-binding protein MDOR_30150 ENOG4105C0D helicase MDOR_30170 ENOG41068WN MDOR_30190 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase MDOR_30200 ENOG41080UU 5-formyltetrahydrofolate cyclo-ligase MDOR_30260 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) MDOR_30270 ENOG4105C0H protease MDOR_30320 ENOG4107QX3 carboxylase MDOR_30350 ENOG4105CGU Enoyl-CoA hydratase MDOR_30390 ENOG4105EET magnesium chelatase MDOR_30400 ENOG4105CHH sulfate transporter MDOR_30500 ENOG4108K5P (LipO)protein MDOR_30530 ENOG4106D2I Chorismate mutase MDOR_30540 ENOG4105EXC Acyl-transferase MDOR_30560 ENOG4107QP8 phosphohexose isomerase MDOR_30590 ENOG4107U9T Pfam:Ribonuclease_BN MDOR_30630 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) MDOR_30650 ENOG4105BZU Histidine kinase MDOR_30730 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) MDOR_30740 ENOG4105DQE DNA ligase MDOR_30750 ENOG4105D7K pfkb domain protein MDOR_30760 ENOG4105FDF Could be involved in DNA repair (By similarity) MDOR_30830 ENOG4105K6V RNA polymerase MDOR_30870 ENOG4107R08 Integrase MDOR_31160 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic MDOR_31170 ENOG4107S1E Beta-lactamase MDOR_31210 ENOG4105E2K Glycosyl transferase (Group 1 MDOR_31250 ENOG4105BZ1 (ABC) transporter MDOR_31260 ENOG4105BZ1 (ABC) transporter MDOR_31270 ENOG4105BZ1 (ABC) transporter MDOR_31310 ENOG41081K0 peptidylprolyl cis-trans isomerase MDOR_31470 ENOG4105FCS tRNA rRNA methyltransferase MDOR_31510 ENOG4108N0W Major Facilitator superfamily MDOR_31530 ENOG4105CHF Glutathione S-transferase MDOR_31540 ENOG4105VEQ Cold shock protein MDOR_31550 ENOG410901E Membrane MDOR_31600 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) MDOR_31640 ENOG4105CFI type iii restriction protein res subunit MDOR_31650 ENOG4105CUB amino acid MDOR_31680 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) MDOR_31700 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase MDOR_31710 ENOG4105CHU acetyl-coa acetyltransferase MDOR_31720 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase MDOR_31800 ENOG4107TB5 TRANSCRIPTIONal MDOR_31850 ENOG4107QJG Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) MDOR_31860 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) MDOR_31870 ENOG4107NHD transcriptional regulator MDOR_31900 ENOG4105KHC sulfurtransferase MDOR_31910 ENOG4105PKJ carbohydrate binding MDOR_31950 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) MDOR_31980 ENOG4105CGD Nad-dependent epimerase dehydratase MDOR_32020 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii MDOR_32030 ENOG4105C3N Participates in control of cell volume in low-osmolarity conditions (By similarity) MDOR_32050 ENOG4105DFM M18 family aminopeptidase MDOR_32080 ENOG410839H phosphoribosylformylglycinamidine synthase MDOR_32130 ENOG4105C8V SAICAR synthetase MDOR_32150 ENOG4105C83 adenylosuccinate lyase MDOR_32160 ENOG4105CUB amino acid MDOR_32170 ENOG4108RFG Tetr family transcriptional regulator MDOR_32270 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase MDOR_32280 ENOG4105C9U ATP-dependent DNA helicase RecQ MDOR_32360 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) MDOR_32390 ENOG4108SGK Tetr family transcriptional regulator MDOR_32420 ENOG4105CC5 ABC transporter MDOR_32430 ENOG4105DIK (ABC) transporter MDOR_32440 ENOG4105DSE periplasmic solute binding protein MDOR_32460 ENOG4105E7Q Cob(II)yrinic acid a,c-diamide reductase MDOR_32530 ENOG4105E7W lamb ycsf family protein MDOR_32540 ENOG4105YVS arsR family transcriptional regulator MDOR_32550 ENOG4105C2C drug resistance transporter, Bcr CflA MDOR_32600 ENOG4105C2N RNA methyltransferase TrmH family group 3 MDOR_32610 ENOG4105C8N cysteinyl-tRNA synthetase MDOR_32620 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) MDOR_32640 ENOG4108VJ1 Transcriptional regulator (CarD family MDOR_32660 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) MDOR_32670 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) MDOR_32690 ENOG4108V9Q carbonic anhydrase MDOR_32700 ENOG4105CEN a g-specific adenine glycosylase MDOR_32740 ENOG4105EBM Alpha Beta Hydrolase Fold protein MDOR_32800 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit MDOR_32820 ENOG4105CRK lysyL-tRNA synthetase MDOR_32840 ENOG4105K63 Thioredoxin MDOR_32930 ENOG4105EEI dihydropteroate synthase MDOR_32940 ENOG4105EUJ GTP cyclohydrolase i MDOR_32950 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) MDOR_32980 ENOG4108UGV hypoxanthine phosphoribosyltransferase MDOR_32990 ENOG4107RD1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) MDOR_33020 ENOG4105F0N pyrophosphate phospho-hydrolase MDOR_33140 ENOG4105MHT Transcriptional regulator, ARSR family MDOR_33150 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase MDOR_33280 ENOG4107QRG dna polymerase iii MDOR_33300 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) MDOR_33320 ENOG4105VEQ Cold shock protein MDOR_33330 ENOG4108I5C dEAD DEAH box helicase MDOR_33430 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) MDOR_33480 ENOG4105P8F nudix hydrolase MDOR_33530 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) MDOR_33580 ENOG4105N0U Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) MDOR_33590 ENOG4108JQC penicillin-binding protein 1A MDOR_33710 ENOG4105C29 acyl-CoA thioesterase MDOR_33740 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) MDOR_33780 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone MDOR_33820 ENOG4108WQ6 secreted protein MDOR_33830 ENOG4105C7R Atpase associated with various cellular activities aaa_3 MDOR_33900 ENOG4105DBE peroxidase MDOR_33990 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) MDOR_34000 ENOG4105C4B ABC transporter, permease MDOR_34010 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease MDOR_34020 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) MDOR_34070 ENOG4105C92 Aminotransferase class V MDOR_34080 ENOG41067HS methyltransferase MDOR_34090 ENOG4108V75 Glutamine amidotransferase MDOR_34100 ENOG4105E46 N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process MDOR_34110 ENOG4105D1K glutamate--cysteine ligase MDOR_34130 ENOG4108ZHJ Organic hydroperoxide resistance protein MDOR_34150 ENOG4108NJC MDOR_34160 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) MDOR_34170 ENOG4105CFH Aspartokinase MDOR_34180 ENOG4105FG0 Nitroreductase MDOR_34210 ENOG4105EYU Glutamine amido-transferase MDOR_34220 ENOG4105M90 Glutamate synthase alpha subunit domain protein MDOR_34230 ENOG4105CBC glutamate synthase MDOR_34280 ENOG4105DMS mur ligase MDOR_34330 ENOG4108RU2 n-acetylmuramoyl-l-alanine amidase MDOR_34360 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase MDOR_34380 ENOG4105XT2 Transcriptional regulator MDOR_34400 ENOG4105C0H protease MDOR_34420 ENOG4105GN4 DNA ligase MDOR_34460 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) MDOR_34480 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) MDOR_34540 ENOG4108Z6B deaminase MDOR_34560 ENOG4105EVN Prephenate dehydrogenase MDOR_34580 ENOG41060H3 Protein of unknown function (DUF1049) MDOR_34620 ENOG4105EUZ Beta-lactamase domain protein MDOR_34630 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase MDOR_34870 ENOG4105MZU cell filamentation protein MDOR_35060 ENOG4108VC7 Protein of unknown function (DUF2587) MDOR_35080 ENOG4108MKI Glycosyl transferase, family 2 MDOR_35140 ENOG4105IQ5 FAD linked oxidase domain protein MDOR_35150 ENOG4108RG3 short-chain dehydrogenase reductase MDOR_35160 ENOG4108K7T Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the addition of the first key arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-5 of a 6-linked galactofuranosyl (Galf) of the galactan domain, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases MDOR_35170 ENOG4105J1Z Arabinosyltransferase MDOR_35180 ENOG4108NUW Cell wall arabinan synthesis protein MDOR_35190 ENOG4105J1Z Arabinosyltransferase MDOR_35200 ENOG4107Y5K Resolvase MDOR_35250 ENOG4105DFU Cell wall formation (By similarity) MDOR_35260 ENOG4105CK5 oxidoreductase MDOR_35270 ENOG4105BZ1 (ABC) transporter MDOR_35300 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) MDOR_35360 ENOG4105F5W AtP-binding protein MDOR_35380 ENOG4106IJN integrase catalytic domain-containing protein MDOR_35420 ENOG4105KAK Plasmid pRiA4b ORF-3 family protein MDOR_35450 ENOG4107RN3 metallophosphoesterase MDOR_35460 ENOG4105D8K carboxyl transferase MDOR_35530 ENOG4107ISF Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) to the arabinan domain to form terminal beta-(1- 2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids MDOR_35540 ENOG4106YN8 Prenyltransferase MDOR_35560 ENOG410602S Transferase MDOR_35620 ENOG4105PSQ Acyl-transferase MDOR_35630 ENOG4107B57 rieske 2fe-2S domain-containing protein MDOR_35740 ENOG4105CQC Prephenate dehydratase MDOR_35780 ENOG4108KGH TRANSCRIPTIONal MDOR_35820 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) MDOR_35890 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) MDOR_35900 ENOG4105CT3 Monooxygenase MDOR_35930 ENOG4105DCG PHP domain protein MDOR_35970 ENOG4105CBC glutamate synthase MDOR_36010 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction MDOR_36120 ENOG4105CEP NADH dehydrogenase MDOR_36140 ENOG4105D70 Integrase catalytic subunit MDOR_36150 ENOG4105F5W AtP-binding protein MDOR_36160 ENOG4105E0X reductase MDOR_36210 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) MDOR_36220 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) MDOR_36270 ENOG4108RWI nicotinamidase MDOR_36300 ENOG4105CC9 acyl-Coa dehydrogenase MDOR_36310 ENOG4105C1G acyl-Coa dehydrogenase MDOR_36320 ENOG41070F3 Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity) MDOR_36330 ENOG4105CG3 alpha amylase, catalytic region MDOR_36350 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) MDOR_36360 ENOG4105D7V transposase MDOR_36410 ENOG4105PP6 Membrane MDOR_36430 ENOG4105EYF MMPL domain protein MDOR_36550 ENOG4105C7R Atpase associated with various cellular activities aaa_3 MDOR_36740 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) MDOR_36750 ENOG4105C3M thioredoxin reductase MDOR_36760 ENOG4105CQ7 ATP-dependent helicase MDOR_36800 ENOG4105CXN decarboxylase MDOR_36830 ENOG4105CI0 Citrate lyase MDOR_36840 ENOG4108JGH Tetr family transcriptional regulator MDOR_36880 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) MDOR_36890 ENOG4105C1Y Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity) MDOR_36900 ENOG4105EM7 Selenocysteine-specific translation elongation factor MDOR_36920 ENOG4105QAX Iron-sulfur MDOR_36980 ENOG4107RCI amp-dependent synthetase and ligase MDOR_37120 ENOG4108JJB ABC transporter MDOR_37130 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein MDOR_37140 ENOG4105D2B acyl-CoA dehydrogenase MDOR_37150 ENOG4105CC9 acyl-Coa dehydrogenase MDOR_37170 ENOG4108W9Q Endoglucanase (EC 3.2.1.4) MDOR_37180 ENOG4105C5X domain protein MDOR_37190 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) MDOR_37210 ENOG4105XTG Pfam:DUF156 MDOR_37240 ENOG410900P UPF0336 protein MDOR_37260 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family MDOR_37270 ENOG4105C6Z Gluconate MDOR_37280 ENOG4108WKN secreted protein MDOR_37300 ENOG4108SGK Tetr family transcriptional regulator MDOR_37330 ENOG4105CK6 Two component transcriptional regulator (Winged helix family MDOR_37340 ENOG4105EB3 Histidine kinase MDOR_37400 ENOG4108YYH Nadph-dependent fmn reductase MDOR_37440 ENOG4105EKQ RNA-directed DNA polymerase MDOR_37450 ENOG410836F Transposase MDOR_37640 ENOG41090EX DsrE family MDOR_37680 ENOG4105J1Z Arabinosyltransferase MDOR_37720 ENOG4108IUN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) MDOR_37850 ENOG4105D70 Integrase catalytic subunit MDOR_37860 ENOG4105F5W AtP-binding protein MDOR_37890 ENOG4105EKQ RNA-directed DNA polymerase MDOR_37960 ENOG4107YH6 single-stranded DNA-binding protein MDOR_37990 ENOG4105BZ4 penicillin-binding protein MDOR_38030 ENOG4105CZA synthase MDOR_38110 ENOG4108R85 Short chain dehydrogenase MDOR_38120 ENOG4105C8T Leucyl-tRNA synthetase MDOR_38130 ENOG41064CH Probable lipoprotein LpqN MDOR_38150 ENOG41081DT UPF0301 protein MDOR_38190 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate MDOR_38240 ENOG4105C3M thioredoxin reductase MDOR_38250 ENOG4105K63 Thioredoxin MDOR_38270 ENOG4108E1C hydrolase MDOR_38300 ENOG4107QJE Chromosome Partitioning Protein MDOR_38310 ENOG4107XUG Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) MDOR_38330 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins MDOR_38340 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) MDOR_38380 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) MDOR_38410 ENOG4105K7N UPF0232 protein MDOR_38420 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) MDOR_38430 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) MDOR_38490 ENOG4107R3N Filamentation induced by cAMP protein fic MDOR_38590 ENOG4105D9P serine threonine protein kinase MDOR_38600 ENOG4107TPY serine threonine protein kinase MDOR_38610 ENOG4105CJN penicillin-binding protein MDOR_38640 ENOG4105HZM Fha domain containing protein MDOR_38650 ENOG4105TV9 FHA Domain-Containing protein MDOR_38740 ENOG4106IJN integrase catalytic domain-containing protein MDOR_38750 ENOG4105F5W AtP-binding protein MDOR_38860 ENOG4105X1Q TOBE domain protein MDOR_38890 ENOG4105GSW MDOR_38990 ENOG4106F1P AAA ATPase, central domain protein MDOR_39120 ENOG4108PZM peptidase S8 and S53, subtilisin, kexin, sedolisin MDOR_39170 ENOG4108UGJ Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity) MDOR_39180 ENOG4105C26 Dehydrogenase MDOR_39190 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr MDOR_39220 ENOG4105C1G acyl-Coa dehydrogenase MDOR_39230 ENOG4105C1G acyl-Coa dehydrogenase MDOR_39240 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) MDOR_39250 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) MDOR_39260 ENOG4108W6C Dehydrogenase MDOR_39290 ENOG4108R86 Transcriptional regulator MDOR_39300 ENOG4105CHR reductase MDOR_39380 ENOG4105CY3 ABC transporter, permease MDOR_39520 ENOG4107RN6 Monooxygenase MDOR_39530 ENOG4105F95 Monooxygenase MDOR_39540 ENOG4105C1G acyl-Coa dehydrogenase MDOR_39550 ENOG4105CC9 acyl-Coa dehydrogenase MDOR_39560 ENOG4105D2B acyl-CoA dehydrogenase MDOR_39590 ENOG4105F95 Monooxygenase MDOR_39600 ENOG4105CEY Amp-dependent synthetase and ligase MDOR_39610 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr MDOR_39630 ENOG4105CHU acetyl-coa acetyltransferase MDOR_39660 ENOG410900P UPF0336 protein MDOR_39670 ENOG4105C1G acyl-Coa dehydrogenase MDOR_39680 ENOG4108KEZ Dehydrogenase MDOR_39700 ENOG4105C1G acyl-Coa dehydrogenase MDOR_39710 ENOG4105CEY Amp-dependent synthetase and ligase MDOR_39740 ENOG4107RN6 Monooxygenase