locus-tag	class	description
MDOR_00030	COG1024	Enoyl-CoA hydratase
MDOR_00060	COG0183	Belongs to the thiolase family
MDOR_00090	COG0183	Belongs to the thiolase family
MDOR_00130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MDOR_00140	COG1024	Enoyl-CoA hydratase
MDOR_00150	COG1024	Enoyl-CoA hydratase
MDOR_00170	COG0318	PFAM AMP-dependent synthetase and ligase
MDOR_00190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDOR_00200	COG1960	acyl-CoA dehydrogenase activity
MDOR_00210	COG2272	Belongs to the type-B carboxylesterase lipase family
MDOR_00270	COG2267	carboxylic ester hydrolase activity
MDOR_00310	COG4122	O-methyltransferase activity
MDOR_00360	COG1937	Protein conserved in bacteria
MDOR_00370	COG1376	ErfK ybiS ycfS ynhG family protein
MDOR_00400	COG0714	Associated with various cellular activities
MDOR_00430	COG3590	peptidase
MDOR_00460	COG1832	CoA-binding protein
MDOR_00480	COG2409	Drug exporters of the RND superfamily
MDOR_00560	COG2409	Drug exporters of the RND superfamily
MDOR_00620	COG2188	Transcriptional regulator
MDOR_00630	COG1960	acyl-CoA dehydrogenase activity
MDOR_00730	COG1960	acyl-CoA dehydrogenase activity
MDOR_00750	COG0297	glycogen (starch) synthase activity
MDOR_00800	COG2814	Major facilitator Superfamily
MDOR_00810	COG4981	capsule polysaccharide biosynthetic process
MDOR_00830	COG1472	Belongs to the glycosyl hydrolase 3 family
MDOR_00860	COG2030	dehydratase
MDOR_00870	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_00880	COG0183	Belongs to the thiolase family
MDOR_00890	COG1960	acyl-CoA dehydrogenase activity
MDOR_00940	COG1053	succinate dehydrogenase
MDOR_00980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MDOR_00980	COG2146	nitrite reductase [NAD(P)H] activity
MDOR_01090	COG0589	response to stress
MDOR_01120	COG2801	Transposase and inactivated derivatives
MDOR_01130	COG2801	Transposase and inactivated derivatives
MDOR_01190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MDOR_01230	COG2252	PERMEase
MDOR_01240	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MDOR_01280	COG0318	PFAM AMP-dependent synthetase and ligase
MDOR_01290	COG1397	ADP-ribosylglycohydrolase
MDOR_01320	COG1960	acyl-CoA dehydrogenase activity
MDOR_01350	COG0469	pyruvate kinase activity
MDOR_01400	COG0723	plastoquinol--plastocyanin reductase activity
MDOR_01400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MDOR_01420	COG4124	Belongs to the glycosyl hydrolase 26 family
MDOR_01420	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MDOR_01440	COG1215	transferase activity, transferring glycosyl groups
MDOR_01450	COG1366	Belongs to the anti-sigma-factor antagonist family
MDOR_01780	COG2181	nitrate reductase activity
MDOR_01780	COG0247	lactate metabolic process
MDOR_01940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDOR_01950	COG0484	heat shock protein binding
MDOR_01960	COG0789	Transcriptional regulator
MDOR_02050	COG0542	response to heat
MDOR_02080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDOR_02110	COG0596	Alpha beta hydrolase
MDOR_02140	COG0586	Pfam SNARE associated Golgi protein
MDOR_02190	COG1994	Peptidase M50
MDOR_02210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDOR_02240	COG3959	Transketolase, thiamine diphosphate binding domain
MDOR_02250	COG2124	cytochrome p450
MDOR_02310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MDOR_02320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDOR_02350	COG0515	serine threonine protein kinase
MDOR_02360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MDOR_02420	COG2022	thiamine diphosphate biosynthetic process
MDOR_02430	COG2234	aminopeptidase activity
MDOR_02440	COG2234	aminopeptidase activity
MDOR_02460	COG2233	PERMEase
MDOR_02520	COG0351	phosphomethylpyrimidine kinase
MDOR_02610	COG2032	superoxide dismutase activity
MDOR_02800	COG1320	monovalent cation:proton antiporter activity
MDOR_02810	COG2212	antiporter activity
MDOR_02840	COG1006	Multisubunit Na H antiporter MnhC subunit
MDOR_02850	COG2111	Na H antiporter
MDOR_02850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MDOR_02860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDOR_03020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MDOR_03050	COG1012	belongs to the aldehyde dehydrogenase family
MDOR_03090	COG1505	serine-type exopeptidase activity
MDOR_03210	COG2733	membrane
MDOR_03410	COG5002	protein histidine kinase activity
MDOR_03420	COG0745	RESPONSE REGULATOR receiver
MDOR_03450	COG0248	Ppx GppA phosphatase
MDOR_03530	COG2030	dehydratase
MDOR_03650	COG0406	alpha-ribazole phosphatase activity
MDOR_03670	COG0785	Cytochrome C biogenesis protein
MDOR_03690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MDOR_03760	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MDOR_03770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MDOR_03780	COG2070	2-Nitropropane dioxygenase
MDOR_03800	COG0745	RESPONSE REGULATOR receiver
MDOR_03850	COG2116	formate transmembrane transporter activity
MDOR_03860	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MDOR_03910	COG4221	oxidoreductase activity
MDOR_03920	COG2205	protein histidine kinase activity
MDOR_03930	COG0745	RESPONSE REGULATOR receiver
MDOR_03980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MDOR_03990	COG1228	amidohydrolase
MDOR_04000	COG4948	Mandelate Racemase Muconate Lactonizing
MDOR_04070	COG0438	transferase activity, transferring glycosyl groups
MDOR_04100	COG0644	oxidoreductase
MDOR_04310	COG4941	Belongs to the sigma-70 factor family
MDOR_04330	COG2197	response regulator
MDOR_04360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MDOR_04370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MDOR_04410	COG2133	pyrroloquinoline quinone binding
MDOR_04430	COG2326	polyphosphate kinase activity
MDOR_04530	COG4977	sequence-specific DNA binding
MDOR_04810	COG2801	Transposase and inactivated derivatives
MDOR_04930	COG4942	peptidase
MDOR_04970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDOR_05050	COG0659	secondary active sulfate transmembrane transporter activity
MDOR_05060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MDOR_05090	COG1074	ATP-dependent DNA helicase activity
MDOR_05100	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MDOR_05120	COG0598	Magnesium transport protein CorA
MDOR_05130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MDOR_05160	COG2030	dehydratase
MDOR_05170	COG2030	dehydratase
MDOR_05190	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MDOR_05230	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDOR_05240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MDOR_05260	COG0653	protein targeting
MDOR_05270	COG3320	Male sterility
MDOR_05270	COG1022	Amp-dependent synthetase and ligase
MDOR_05350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDOR_05410	COG0450	alkyl hydroperoxide reductase
MDOR_05420	COG0438	transferase activity, transferring glycosyl groups
MDOR_05500	COG0443	Heat shock 70 kDa protein
MDOR_05510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDOR_05540	COG0542	response to heat
MDOR_05580	COG0489	protein tyrosine kinase activity
MDOR_05610	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MDOR_05740	COG3307	-O-antigen
MDOR_05800	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MDOR_05810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MDOR_05840	COG2755	lipolytic protein G-D-S-L family
MDOR_05840	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MDOR_05870	COG2963	transposase activity
MDOR_05900	COG2390	Transcriptional regulator
MDOR_05900	COG4584	PFAM Integrase catalytic
MDOR_06120	COG1960	acyl-CoA dehydrogenase activity
MDOR_06150	COG1024	Enoyl-CoA hydratase
MDOR_06160	COG1454	alcohol dehydrogenase
MDOR_06270	COG0535	radical SAM domain protein
MDOR_06320	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MDOR_06340	COG2272	Belongs to the type-B carboxylesterase lipase family
MDOR_06350	COG0051	transcription antitermination factor activity, RNA binding
MDOR_06450	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDOR_06470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MDOR_06540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDOR_06550	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDOR_06570	COG0200	Binds to the 23S rRNA
MDOR_06600	COG0616	signal peptide processing
MDOR_06620	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MDOR_06690	COG2197	response regulator
MDOR_06720	COG1960	acyl-CoA dehydrogenase activity
MDOR_06740	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MDOR_06750	COG1088	dTDP-glucose 4,6-dehydratase activity
MDOR_06770	COG1063	alcohol dehydrogenase
MDOR_07010	COG1253	flavin adenine dinucleotide binding
MDOR_07020	COG0561	phosphatase activity
MDOR_07030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MDOR_07090	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDOR_07100	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDOR_07190	COG1404	Belongs to the peptidase S8 family
MDOR_07210	COG1674	ftsk spoiiie
MDOR_07230	COG4842	Belongs to the WXG100 family
MDOR_07240	COG4842	Belongs to the WXG100 family
MDOR_07250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDOR_07310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDOR_07330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MDOR_07350	COG0076	glutamate decarboxylase activity
MDOR_07360	COG0076	glutamate decarboxylase activity
MDOR_07370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDOR_07410	COG0456	acetyltransferase
MDOR_07440	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDOR_07470	COG2130	NADP-dependent
MDOR_07480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MDOR_07550	COG0516	GMP reductase activity
MDOR_07590	COG0519	Catalyzes the synthesis of GMP from XMP
MDOR_07590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MDOR_07660	COG1846	Transcriptional regulator
MDOR_07680	COG0587	DNA-directed DNA polymerase activity
MDOR_07720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MDOR_07740	COG5002	protein histidine kinase activity
MDOR_07750	COG2018	Roadblock/LC7 domain
MDOR_07790	COG1305	Transglutaminase-like
MDOR_07810	COG1716	ATPase activity
MDOR_07810	COG1131	(ABC) transporter
MDOR_07810	COG0842	Transport permease protein
MDOR_07860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDOR_07960	COG2873	o-acetylhomoserine
MDOR_08000	COG1295	ribonuclease BN
MDOR_08010	COG2184	nucleotidyltransferase activity
MDOR_08040	COG0010	Belongs to the arginase family
MDOR_08050	COG1686	Belongs to the peptidase S11 family
MDOR_08070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MDOR_08080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MDOR_08150	COG2009	succinate dehydrogenase
MDOR_08240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDOR_08270	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MDOR_08270	COG1473	amidohydrolase
MDOR_08310	COG0564	pseudouridine synthase activity
MDOR_08370	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MDOR_08380	COG3639	organic phosphonate transmembrane transporter activity
MDOR_08390	COG2188	Transcriptional regulator
MDOR_08430	COG3627	carbon phosphorus lyase activity
MDOR_08440	COG4107	phosphonate C-P lyase system protein PhnK
MDOR_08510	COG1140	nitrate reductase beta subunit
MDOR_08550	COG1201	RNA secondary structure unwinding
MDOR_08560	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_08580	COG1012	belongs to the aldehyde dehydrogenase family
MDOR_08590	COG1522	sequence-specific DNA binding
MDOR_08660	COG0297	glycogen (starch) synthase activity
MDOR_08670	COG1215	transferase activity, transferring glycosyl groups
MDOR_08690	COG2192	nodulation
MDOR_08700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MDOR_08710	COG0859	PFAM glycosyl transferase family 9
MDOR_08720	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MDOR_08730	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MDOR_08730	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MDOR_08740	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_08830	COG2188	Transcriptional regulator
MDOR_08860	COG4770	biotin carboxylase activity
MDOR_08920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MDOR_08970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDOR_08990	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MDOR_08990	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MDOR_09010	COG1316	TRANSCRIPTIONal
MDOR_09020	COG1091	dTDP-4-dehydrorhamnose reductase activity
MDOR_09060	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MDOR_09060	COG0778	Nitroreductase
MDOR_09130	COG1482	cell wall glycoprotein biosynthetic process
MDOR_09140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MDOR_09150	COG0531	amino acid
MDOR_09260	COG0745	RESPONSE REGULATOR receiver
MDOR_09270	COG5002	protein histidine kinase activity
MDOR_09300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDOR_09380	COG0656	L-ascorbic acid biosynthetic process
MDOR_09430	COG1595	DNA-templated transcription, initiation
MDOR_09440	COG5662	AntiSigma factor
MDOR_09460	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MDOR_09500	COG1597	lipid kinase activity
MDOR_09540	COG0406	alpha-ribazole phosphatase activity
MDOR_09660	COG0596	Alpha beta hydrolase
MDOR_09720	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MDOR_09760	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MDOR_09770	COG3383	formate dehydrogenase (NAD+) activity
MDOR_09780	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
MDOR_09790	COG3259	Nickel-dependent hydrogenase
MDOR_09840	COG0409	Hydrogenase expression formation protein
MDOR_09850	COG0298	carbon dioxide binding
MDOR_09860	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MDOR_09870	COG0375	protein maturation
MDOR_09920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MDOR_09950	COG3480	Lon protease (S16) C-terminal proteolytic domain
MDOR_09990	COG1196	nuclear chromosome segregation
MDOR_10000	COG1396	sequence-specific DNA binding
MDOR_10010	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
MDOR_10020	COG0582	viral genome integration into host DNA
MDOR_10060	COG2801	Transposase and inactivated derivatives
MDOR_10240	COG2801	Transposase and inactivated derivatives
MDOR_10350	COG2801	Transposase and inactivated derivatives
MDOR_10420	COG4584	PFAM Integrase catalytic
MDOR_10430	COG1484	DNA-dependent DNA replication
MDOR_10490	COG0640	Transcriptional regulator
MDOR_10510	COG1309	transcriptional regulator
MDOR_10540	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MDOR_10570	COG0247	lactate metabolic process
MDOR_10570	COG0277	FAD linked oxidase domain protein
MDOR_10600	COG2267	carboxylic ester hydrolase activity
MDOR_10610	COG2072	flavoprotein involved in K transport
MDOR_10620	COG1024	Enoyl-CoA hydratase
MDOR_10700	COG1034	ATP synthesis coupled electron transport
MDOR_10780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MDOR_10790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MDOR_10800	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MDOR_10810	COG1960	acyl-CoA dehydrogenase activity
MDOR_10830	COG0483	inositol monophosphate 1-phosphatase activity
MDOR_10870	COG0668	transmembrane transport
MDOR_10890	COG2884	Cell division ATP-binding protein ftsE
MDOR_10900	COG2177	Part of the ABC transporter FtsEX involved in
MDOR_10930	COG2072	flavoprotein involved in K transport
MDOR_10940	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MDOR_10950	COG3583	domain protein
MDOR_10980	COG3842	ATPase activity
MDOR_11030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MDOR_11030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MDOR_11040	COG2188	Transcriptional regulator
MDOR_11080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDOR_11100	COG0477	Major facilitator Superfamily
MDOR_11250	COG0662	Cupin 2, conserved barrel domain protein
MDOR_11260	COG1960	acyl-CoA dehydrogenase activity
MDOR_11310	COG0590	tRNA wobble adenosine to inosine editing
MDOR_11320	COG2076	Multidrug Resistance protein
MDOR_11350	COG0673	inositol 2-dehydrogenase activity
MDOR_11370	COG1279	arginine transmembrane transporter activity
MDOR_11410	COG3344	reverse transcriptase
MDOR_11440	COG2801	Transposase and inactivated derivatives
MDOR_11500	COG2264	protein methyltransferase activity
MDOR_11650	COG2801	Transposase and inactivated derivatives
MDOR_11670	COG1484	DNA-dependent DNA replication
MDOR_11680	COG4584	PFAM Integrase catalytic
MDOR_11750	COG0450	alkyl hydroperoxide reductase
MDOR_11780	COG1271	oxidase subunit
MDOR_11790	COG1376	ErfK ybiS ycfS ynhG family protein
MDOR_11800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDOR_11800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MDOR_11840	COG2188	Transcriptional regulator
MDOR_11860	COG1484	DNA-dependent DNA replication
MDOR_11870	COG4584	PFAM Integrase catalytic
MDOR_11900	COG2801	Transposase and inactivated derivatives
MDOR_11930	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MDOR_11940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MDOR_11940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MDOR_11950	COG0785	Cytochrome C biogenesis protein
MDOR_12070	COG1960	acyl-CoA dehydrogenase activity
MDOR_12090	COG0183	Belongs to the thiolase family
MDOR_12100	COG1960	acyl-CoA dehydrogenase activity
MDOR_12110	COG1802	Transcriptional regulator
MDOR_12200	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_12270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDOR_12310	COG1309	transcriptional regulator
MDOR_12340	COG1064	alcohol dehydrogenase
MDOR_12400	COG1309	transcriptional regulator
MDOR_12420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDOR_12430	COG0601	transmembrane transport
MDOR_12450	COG0747	negative chemotaxis
MDOR_12470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MDOR_12480	COG4266	Belongs to the allantoicase family
MDOR_12530	COG3830	Belongs to the UPF0237 family
MDOR_12530	COG0560	Phosphoserine phosphatase
MDOR_12540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MDOR_12550	COG1119	ATPase activity
MDOR_12610	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MDOR_12620	COG0110	maltose O-acetyltransferase activity
MDOR_12650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MDOR_12670	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MDOR_12750	COG0318	PFAM AMP-dependent synthetase and ligase
MDOR_12780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDOR_12870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDOR_12910	COG2226	methyltransferase
MDOR_12960	COG0440	acetolactate synthase activity
MDOR_13020	COG3546	catalase activity
MDOR_13040	COG2271	Major facilitator Superfamily
MDOR_13050	COG0179	Fumarylacetoacetate (FAA) hydrolase
MDOR_13120	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MDOR_13150	COG0626	cystathionine gamma-synthase activity
MDOR_13220	COG1461	Dihydroxyacetone kinase
MDOR_13230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDOR_13310	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MDOR_13320	COG0742	ribosomal rna small subunit methyltransferase
MDOR_13350	COG3599	regulation of cell shape
MDOR_13370	COG0571	ribonuclease III activity
MDOR_13420	COG1304	FMN binding
MDOR_13460	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MDOR_13560	COG0336	Belongs to the RNA methyltransferase TrmD family
MDOR_13680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MDOR_13700	COG0318	PFAM AMP-dependent synthetase and ligase
MDOR_13710	COG3842	ATPase activity
MDOR_13740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDOR_13890	COG2801	Transposase and inactivated derivatives
MDOR_13920	COG1136	(ABC) transporter
MDOR_13950	COG1929	Belongs to the glycerate kinase type-1 family
MDOR_14070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MDOR_14080	COG0750	zinc metalloprotease
MDOR_14170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDOR_14170	COG0189	ligase activity
MDOR_14180	COG0367	asparagine synthase
MDOR_14200	COG0174	glutamine synthetase
MDOR_14210	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MDOR_14220	COG1012	belongs to the aldehyde dehydrogenase family
MDOR_14230	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_14300	COG1122	ATPase activity
MDOR_14380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MDOR_14380	COG1648	precorrin-2 dehydrogenase activity
MDOR_14470	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MDOR_14490	COG2226	methyltransferase
MDOR_14600	COG3012	SEC-C Motif Domain Protein
MDOR_14610	COG0686	Belongs to the AlaDH PNT family
MDOR_14620	COG1522	sequence-specific DNA binding
MDOR_14710	COG3214	Protein conserved in bacteria
MDOR_14730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDOR_14740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDOR_14770	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MDOR_14790	COG1058	Belongs to the CinA family
MDOR_14790	COG1546	Belongs to the CinA family
MDOR_14800	COG1396	sequence-specific DNA binding
MDOR_14830	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
MDOR_14890	COG0409	Hydrogenase expression formation protein
MDOR_14900	COG0298	carbon dioxide binding
MDOR_14910	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MDOR_14920	COG0298	carbon dioxide binding
MDOR_14990	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
MDOR_15020	COG0375	protein maturation
MDOR_15090	COG0765	amino acid transport
MDOR_15100	COG0765	amino acid transport
MDOR_15110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MDOR_15120	COG1126	abc transporter atp-binding protein
MDOR_15150	COG1196	nuclear chromosome segregation
MDOR_15170	COG0697	spore germination
MDOR_15210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDOR_15220	COG0513	Belongs to the DEAD box helicase family
MDOR_15260	COG1388	LysM domain
MDOR_15450	COG0483	inositol monophosphate 1-phosphatase activity
MDOR_15550	COG0569	domain protein
MDOR_15560	COG0531	amino acid
MDOR_15570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDOR_15610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MDOR_15660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDOR_15720	COG1595	DNA-templated transcription, initiation
MDOR_15790	COG4762	Protein conserved in bacteria
MDOR_15840	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDOR_15850	COG1560	Kdo2-lipid A biosynthetic process
MDOR_15860	COG0438	transferase activity, transferring glycosyl groups
MDOR_15880	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MDOR_15890	COG1946	Acyl-CoA thioesterase
MDOR_16020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MDOR_16030	COG0747	negative chemotaxis
MDOR_16050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDOR_16080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MDOR_16090	COG0124	histidyl-tRNA synthetase
MDOR_16160	COG1278	Cold shock
MDOR_16200	COG2272	Belongs to the type-B carboxylesterase lipase family
MDOR_16320	COG0432	Pfam Uncharacterised protein family UPF0047
MDOR_16350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDOR_16410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MDOR_16440	COG0006	proline dipeptidase activity
MDOR_16450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDOR_16480	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDOR_16520	COG0505	Belongs to the CarA family
MDOR_16590	COG1758	RNA polymerase activity
MDOR_16690	COG0477	Major facilitator Superfamily
MDOR_16720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MDOR_16720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MDOR_16750	COG0456	acetyltransferase
MDOR_16820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MDOR_16840	COG0149	triose-phosphate isomerase activity
MDOR_16870	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MDOR_16920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MDOR_17050	COG0396	ATPase activity
MDOR_17070	COG0822	iron-sulfur transferase activity
MDOR_17080	COG2151	metal-sulfur cluster biosynthetic enzyme
MDOR_17150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MDOR_17160	COG0488	(ABC) transporter
MDOR_17170	COG1309	transcriptional regulator
MDOR_17180	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MDOR_17210	COG0791	NLP P60 protein
MDOR_17210	COG3883	PFAM NLP P60 protein
MDOR_17230	COG0714	Associated with various cellular activities
MDOR_17260	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_17270	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MDOR_17350	COG2378	regulation of single-species biofilm formation
MDOR_17430	COG0300	oxidoreductase activity
MDOR_17530	COG1228	amidohydrolase
MDOR_17540	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MDOR_17550	COG0463	Glycosyl transferase, family 2
MDOR_17580	COG0514	ATP-dependent DNA helicase (RecQ)
MDOR_17740	COG3654	unkown
MDOR_17750	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MDOR_17750	COG2308	Evidence 4 Homologs of previously reported genes of
MDOR_17760	COG0367	asparagine synthase
MDOR_17780	COG1484	DNA-dependent DNA replication
MDOR_17810	COG4584	PFAM Integrase catalytic
MDOR_17830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDOR_17840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MDOR_17840	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MDOR_17880	COG0601	transmembrane transport
MDOR_17890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDOR_17920	COG0431	NADPH-dependent FMN reductase
MDOR_17990	COG2197	response regulator
MDOR_18000	COG0747	negative chemotaxis
MDOR_18010	COG0601	transmembrane transport
MDOR_18020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDOR_18030	COG0444	Belongs to the ABC transporter superfamily
MDOR_18050	COG0154	amidase activity
MDOR_18080	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MDOR_18090	COG0830	nickel cation binding
MDOR_18100	COG0832	Belongs to the urease beta subunit family
MDOR_18100	COG0831	urea catabolic process
MDOR_18110	COG0804	urea catabolic process
MDOR_18120	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MDOR_18130	COG0829	nickel cation binding
MDOR_18140	COG2161	toxin-antitoxin pair type II binding
MDOR_18150	COG2026	Addiction module toxin, RelE StbE family
MDOR_18220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDOR_18320	COG1404	Belongs to the peptidase S8 family
MDOR_18380	COG0450	alkyl hydroperoxide reductase
MDOR_18390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MDOR_18390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDOR_18410	COG1937	Protein conserved in bacteria
MDOR_18420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MDOR_18440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDOR_18480	COG0785	Cytochrome C biogenesis protein
MDOR_18540	COG0640	Transcriptional regulator
MDOR_18620	COG2963	transposase activity
MDOR_18630	COG2801	Transposase and inactivated derivatives
MDOR_18700	COG1376	ErfK ybiS ycfS ynhG family protein
MDOR_18740	COG1845	cytochrome c oxidase, subunit III
MDOR_18830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MDOR_18850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MDOR_18870	COG2217	Heavy metal translocating P-type atpase
MDOR_18890	COG1376	ErfK ybiS ycfS ynhG family protein
MDOR_18910	COG0785	Cytochrome C biogenesis protein
MDOR_18930	COG3336	cytochrome c oxidase
MDOR_19030	COG2205	protein histidine kinase activity
MDOR_19040	COG0745	RESPONSE REGULATOR receiver
MDOR_19060	COG0791	NLP P60 protein
MDOR_19060	COG3883	PFAM NLP P60 protein
MDOR_19090	COG0745	RESPONSE REGULATOR receiver
MDOR_19110	COG1376	ErfK ybiS ycfS ynhG family protein
MDOR_19170	COG1937	Protein conserved in bacteria
MDOR_19180	COG2217	Heavy metal translocating P-type atpase
MDOR_19210	COG2801	Transposase and inactivated derivatives
MDOR_19230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MDOR_19240	COG3842	ATPase activity
MDOR_19350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDOR_19430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDOR_19490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MDOR_19570	COG0464	growth
MDOR_19640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MDOR_19670	COG1196	nuclear chromosome segregation
MDOR_19700	COG2337	Toxic component of a toxin-antitoxin (TA) module
MDOR_19760	COG1216	Glycosyl transferase, family 2
MDOR_19870	COG0545	Peptidyl-prolyl cis-trans isomerase
MDOR_19890	COG2354	Protein conserved in bacteria
MDOR_19900	COG0791	NLP P60 protein
MDOR_19900	COG3883	PFAM NLP P60 protein
MDOR_19930	COG1012	belongs to the aldehyde dehydrogenase family
MDOR_19980	COG2755	lipolytic protein G-D-S-L family
MDOR_20020	COG0745	RESPONSE REGULATOR receiver
MDOR_20030	COG4251	negative regulation of phosphorylation
MDOR_20040	COG0784	Response regulator, receiver
MDOR_20060	COG3022	response to hydroperoxide
MDOR_20110	COG3588	fructose-bisphosphate aldolase
MDOR_20260	COG1376	ErfK ybiS ycfS ynhG family protein
MDOR_20270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MDOR_20340	COG0438	transferase activity, transferring glycosyl groups
MDOR_20370	COG0174	glutamine synthetase
MDOR_20390	COG2193	ferroxidase activity
MDOR_20440	COG1335	isochorismatase
MDOR_20540	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MDOR_20610	COG1252	NADH dehydrogenase
MDOR_20620	COG0829	nickel cation binding
MDOR_20720	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDOR_20740	COG1253	flavin adenine dinucleotide binding
MDOR_20750	COG1253	flavin adenine dinucleotide binding
MDOR_20800	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MDOR_20800	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MDOR_20840	COG1716	ATPase activity
MDOR_20940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MDOR_20940	COG4651	solute:proton antiporter activity
MDOR_20960	COG2272	Belongs to the type-B carboxylesterase lipase family
MDOR_20980	COG2076	Multidrug Resistance protein
MDOR_21020	COG4221	oxidoreductase activity
MDOR_21060	COG0693	protein deglycase activity
MDOR_21120	COG0596	Alpha beta hydrolase
MDOR_21230	COG0515	serine threonine protein kinase
MDOR_21240	COG1388	LysM domain
MDOR_21250	COG2186	Transcriptional regulator
MDOR_21260	COG1914	H( )-stimulated, divalent metal cation uptake system
MDOR_21270	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MDOR_21290	COG4336	lyase activity
MDOR_21390	COG0730	response to heat
MDOR_21400	COG1160	GTP binding
MDOR_21430	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDOR_21520	COG0497	DNA recombination
MDOR_21560	COG0647	UMP catabolic process
MDOR_21600	COG2835	tetraacyldisaccharide 4'-kinase activity
MDOR_21630	COG0488	(ABC) transporter
MDOR_21680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MDOR_21690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MDOR_21710	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MDOR_21730	COG0072	phenylalanine-tRNA ligase activity
MDOR_21730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDOR_21740	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDOR_21760	COG1960	acyl-CoA dehydrogenase activity
MDOR_21770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDOR_21850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MDOR_21890	COG2205	protein histidine kinase activity
MDOR_21950	COG0798	PFAM Bile acid sodium symporter
MDOR_21970	COG0640	Transcriptional regulator
MDOR_22030	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDOR_22030	COG0237	dephospho-CoA kinase activity
MDOR_22040	COG0539	negative regulation of cytoplasmic translation
MDOR_22160	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_22200	COG0783	Belongs to the Dps family
MDOR_22210	COG1126	abc transporter atp-binding protein
MDOR_22260	COG1946	Acyl-CoA thioesterase
MDOR_22290	COG0069	glutamate synthase activity
MDOR_22290	COG0067	glutamate synthase
MDOR_22290	COG0070	glutamate synthase
MDOR_22370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MDOR_22400	COG0483	inositol monophosphate 1-phosphatase activity
MDOR_22420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MDOR_22480	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MDOR_22600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MDOR_22720	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDOR_22730	COG0252	asparaginase activity
MDOR_22750	COG2501	S4 domain
MDOR_22760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDOR_22870	COG1215	transferase activity, transferring glycosyl groups
MDOR_22890	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDOR_22900	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDOR_22960	COG3321	synthase
MDOR_22960	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_22960	COG0604	alcohol dehydrogenase
MDOR_23120	COG4122	O-methyltransferase activity
MDOR_23240	COG0477	Major facilitator Superfamily
MDOR_23340	COG1218	3'(2'),5'-bisphosphate nucleotidase
MDOR_23440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MDOR_23480	COG2409	Drug exporters of the RND superfamily
MDOR_23480	COG1033	growth of symbiont in host cell
MDOR_23490	COG0243	molybdopterin cofactor binding
MDOR_23500	COG2223	nitrite transmembrane transporter activity
MDOR_23520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MDOR_23530	COG2146	nitrite reductase [NAD(P)H] activity
MDOR_23580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MDOR_23580	COG0519	Catalyzes the synthesis of GMP from XMP
MDOR_23690	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MDOR_23730	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDOR_23770	COG0768	penicillin binding
MDOR_23880	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MDOR_23910	COG5650	phosphatidylinositol metabolic process
MDOR_23980	COG0438	transferase activity, transferring glycosyl groups
MDOR_24030	COG1845	cytochrome c oxidase, subunit III
MDOR_24120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDOR_24190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MDOR_24310	COG0174	glutamine synthetase
MDOR_24320	COG1490	D-aminoacyl-tRNA deacylase activity
MDOR_24340	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MDOR_24350	COG0174	glutamine synthetase
MDOR_24400	COG2813	Specifically methylates the guanine in position
MDOR_24410	COG0492	ferredoxin-NADP+ reductase activity
MDOR_24420	COG1396	sequence-specific DNA binding
MDOR_24500	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MDOR_24790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MDOR_24800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDOR_24810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MDOR_24910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MDOR_24930	COG0747	negative chemotaxis
MDOR_24960	COG4172	Belongs to the ABC transporter superfamily
MDOR_25050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDOR_25050	COG0574	Belongs to the PEP-utilizing enzyme family
MDOR_25350	COG5522	Integral membrane protein (intg_mem_TP0381)
MDOR_25410	COG2814	Major facilitator Superfamily
MDOR_25470	COG0358	DNA primase activity
MDOR_25500	COG0423	glycine-tRNA ligase activity
MDOR_25540	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDOR_25640	COG0484	heat shock protein binding
MDOR_25740	COG3387	PFAM Glycoside hydrolase 15-related
MDOR_25790	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MDOR_25810	COG0713	ATP synthesis coupled electron transport
MDOR_25830	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MDOR_25880	COG1305	Transglutaminase-like
MDOR_25940	COG1555	photosystem II stabilization
MDOR_25940	COG1596	polysaccharide export
MDOR_25970	COG2755	lipolytic protein G-D-S-L family
MDOR_25980	COG0406	alpha-ribazole phosphatase activity
MDOR_25990	COG0799	negative regulation of ribosome biogenesis
MDOR_26020	COG0542	response to heat
MDOR_26040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDOR_26100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDOR_26140	COG1530	ribonuclease E activity
MDOR_26170	COG0285	dihydrofolate synthase activity
MDOR_26180	COG0525	valine-tRNA ligase activity
MDOR_26190	COG3268	Saccharopine dehydrogenase
MDOR_26200	COG0823	Involved in the tonB-independent uptake of proteins
MDOR_26200	COG1506	peptidase
MDOR_26230	COG1388	LysM domain
MDOR_26240	COG0746	molybdenum cofactor guanylyltransferase activity
MDOR_26250	COG1013	pyruvate-flavodoxin oxidoreductase activity
MDOR_26260	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MDOR_26260	COG0674	pyruvate-flavodoxin oxidoreductase activity
MDOR_26280	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MDOR_26310	COG0740	serine-type endopeptidase activity
MDOR_26360	COG0243	molybdopterin cofactor binding
MDOR_26410	COG1022	Amp-dependent synthetase and ligase
MDOR_26420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MDOR_26450	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MDOR_26490	COG0366	Alpha amylase catalytic
MDOR_26520	COG2902	Dehydrogenase
MDOR_26560	COG2937	Belongs to the GPAT DAPAT family
MDOR_26670	COG0508	dehydrogenase complex catalyzes the overall conversion of
MDOR_26710	COG2030	dehydratase
MDOR_26720	COG1960	acyl-CoA dehydrogenase activity
MDOR_26740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MDOR_26760	COG2030	dehydratase
MDOR_26770	COG4221	oxidoreductase activity
MDOR_26830	COG0300	oxidoreductase activity
MDOR_26850	COG1376	ErfK ybiS ycfS ynhG family protein
MDOR_26880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MDOR_26930	COG2271	Major facilitator Superfamily
MDOR_26960	COG0183	Belongs to the thiolase family
MDOR_27020	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDOR_27040	COG1234	tRNA 3'-trailer cleavage
MDOR_27050	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MDOR_27130	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDOR_27160	COG0058	SHG alpha-glucan phosphorylase activity
MDOR_27170	COG0366	Alpha amylase catalytic
MDOR_27200	COG2409	Drug exporters of the RND superfamily
MDOR_27210	COG0183	Belongs to the thiolase family
MDOR_27220	COG0346	lactoylglutathione lyase activity
MDOR_27260	COG0318	PFAM AMP-dependent synthetase and ligase
MDOR_27270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDOR_27390	COG0356	it plays a direct role in the translocation of protons across the membrane
MDOR_27410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDOR_27430	COG2890	protein-(glutamine-N5) methyltransferase activity
MDOR_27480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MDOR_27490	COG0460	homoserine dehydrogenase
MDOR_27500	COG0019	diaminopimelate decarboxylase activity
MDOR_27560	COG1218	3'(2'),5'-bisphosphate nucleotidase
MDOR_27630	COG2801	Transposase and inactivated derivatives
MDOR_27640	COG2205	protein histidine kinase activity
MDOR_27650	COG0745	RESPONSE REGULATOR receiver
MDOR_27780	COG2608	mercury ion transmembrane transporter activity
MDOR_27820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDOR_27860	COG0277	FAD linked oxidase domain protein
MDOR_27920	COG2814	Major facilitator Superfamily
MDOR_27970	COG0598	Magnesium transport protein CorA
MDOR_28060	COG2239	Acts as a magnesium transporter
MDOR_28110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDOR_28120	COG5662	AntiSigma factor
MDOR_28130	COG1595	DNA-templated transcription, initiation
MDOR_28170	COG0297	glycogen (starch) synthase activity
MDOR_28190	COG0519	Catalyzes the synthesis of GMP from XMP
MDOR_28210	COG0463	Glycosyl transferase, family 2
MDOR_28230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MDOR_28240	COG1611	Belongs to the LOG family
MDOR_28250	COG0488	(ABC) transporter
MDOR_28260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MDOR_28280	COG1937	Protein conserved in bacteria
MDOR_28300	COG0318	PFAM AMP-dependent synthetase and ligase
MDOR_28360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MDOR_28370	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MDOR_28430	COG0747	negative chemotaxis
MDOR_28470	COG1051	belongs to the nudix hydrolase family
MDOR_28530	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDOR_28570	COG3467	pyridoxamine 5'-phosphate
MDOR_28590	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MDOR_28620	COG2801	Transposase and inactivated derivatives
MDOR_28640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MDOR_28680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MDOR_28690	COG1024	Enoyl-CoA hydratase
MDOR_28710	COG0702	epimerase
MDOR_28740	COG1960	acyl-CoA dehydrogenase activity
MDOR_28750	COG1024	Enoyl-CoA hydratase
MDOR_28760	COG0183	Belongs to the thiolase family
MDOR_28770	COG2186	Transcriptional regulator
MDOR_28850	COG0012	GTP binding
MDOR_29000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MDOR_29020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDOR_29050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDOR_29070	COG1331	Highly conserved protein containing a thioredoxin domain
MDOR_29090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MDOR_29110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MDOR_29140	COG1960	acyl-CoA dehydrogenase activity
MDOR_29150	COG5473	translation initiation factor activity
MDOR_29170	COG0657	acetylesterase activity
MDOR_29180	COG2755	lipolytic protein G-D-S-L family
MDOR_29190	COG0183	Belongs to the thiolase family
MDOR_29210	COG1024	Enoyl-CoA hydratase
MDOR_29280	COG0183	Belongs to the thiolase family
MDOR_29360	COG0038	chloride channel
MDOR_29430	COG0633	Ferredoxin
MDOR_29460	COG4191	Histidine kinase
MDOR_29470	COG2197	response regulator
MDOR_29810	COG2822	iron ion transport
MDOR_29820	COG2837	iron assimilation
MDOR_29830	COG3956	TIGRFAM MazG family protein
MDOR_29850	COG1309	transcriptional regulator
MDOR_29910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MDOR_29940	COG0318	PFAM AMP-dependent synthetase and ligase
MDOR_29950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MDOR_29970	COG3583	domain protein
MDOR_29980	COG0084	hydrolase, TatD family'
MDOR_30000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MDOR_30060	COG2235	arginine
MDOR_30110	COG3391	amine dehydrogenase activity
MDOR_30110	COG5651	PPE family
MDOR_30120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MDOR_30120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MDOR_30130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MDOR_30130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MDOR_30150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MDOR_30170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MDOR_30190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MDOR_30200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDOR_30260	COG0315	cyclic pyranopterin monophosphate synthase activity
MDOR_30260	COG0521	Mo-molybdopterin cofactor biosynthetic process
MDOR_30270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDOR_30320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MDOR_30350	COG1024	Enoyl-CoA hydratase
MDOR_30390	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MDOR_30400	COG0659	secondary active sulfate transmembrane transporter activity
MDOR_30530	COG1605	Chorismate mutase
MDOR_30540	COG2755	lipolytic protein G-D-S-L family
MDOR_30540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MDOR_30560	COG0166	Belongs to the GPI family
MDOR_30570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MDOR_30590	COG1295	ribonuclease BN
MDOR_30600	COG0028	Belongs to the TPP enzyme family
MDOR_30630	COG2201	protein-glutamate methylesterase activity
MDOR_30680	COG2207	Transcriptional regulator
MDOR_30730	COG0328	RNA-DNA hybrid ribonuclease activity
MDOR_30740	COG3285	dna ligase
MDOR_30740	COG1793	dna ligase
MDOR_30750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDOR_30760	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MDOR_30870	COG0582	viral genome integration into host DNA
MDOR_30880	COG2801	Transposase and inactivated derivatives
MDOR_31030	COG2801	Transposase and inactivated derivatives
MDOR_31160	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MDOR_31210	COG0438	transferase activity, transferring glycosyl groups
MDOR_31250	COG1132	(ABC) transporter
MDOR_31260	COG1132	(ABC) transporter
MDOR_31270	COG1132	(ABC) transporter
MDOR_31280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MDOR_31310	COG0545	Peptidyl-prolyl cis-trans isomerase
MDOR_31370	COG1309	transcriptional regulator
MDOR_31470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDOR_31510	COG2814	Major facilitator Superfamily
MDOR_31530	COG0435	Glutathione S-transferase
MDOR_31540	COG1278	Cold shock
MDOR_31550	COG3304	Inner membrane component domain
MDOR_31600	COG0315	cyclic pyranopterin monophosphate synthase activity
MDOR_31600	COG0521	Mo-molybdopterin cofactor biosynthetic process
MDOR_31640	COG1061	Type III restriction enzyme res subunit
MDOR_31650	COG0531	amino acid
MDOR_31680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDOR_31700	COG1250	3-hydroxyacyl-CoA dehydrogenase
MDOR_31700	COG1024	Enoyl-CoA hydratase
MDOR_31710	COG0183	Belongs to the thiolase family
MDOR_31720	COG1902	pentaerythritol trinitrate reductase activity
MDOR_31800	COG1316	TRANSCRIPTIONal
MDOR_31870	COG0745	RESPONSE REGULATOR receiver
MDOR_31890	COG3118	belongs to the thioredoxin family
MDOR_31900	COG2897	thiosulfate sulfurtransferase activity
MDOR_31980	COG0702	epimerase
MDOR_32020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDOR_32030	COG3263	regulation of cellular component size
MDOR_32050	COG1362	aminopeptidase activity
MDOR_32080	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDOR_32110	COG0386	Belongs to the glutathione peroxidase family
MDOR_32150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDOR_32160	COG0531	amino acid
MDOR_32170	COG3226	Transcriptional regulator
MDOR_32250	COG1024	Enoyl-CoA hydratase
MDOR_32280	COG0514	ATP-dependent DNA helicase (RecQ)
MDOR_32340	COG0436	Aminotransferase
MDOR_32360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MDOR_32370	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_32390	COG1309	transcriptional regulator
MDOR_32410	COG1609	Transcriptional regulator
MDOR_32430	COG1121	(ABC) transporter
MDOR_32440	COG0803	Belongs to the bacterial solute-binding protein 9 family
MDOR_32460	COG0778	Nitroreductase
MDOR_32490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MDOR_32530	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MDOR_32540	COG0640	Transcriptional regulator
MDOR_32550	COG2814	Major facilitator Superfamily
MDOR_32630	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MDOR_32640	COG1329	Transcriptional regulator
MDOR_32660	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDOR_32670	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MDOR_32690	COG0288	reversible hydration of carbon dioxide
MDOR_32700	COG1194	a g-specific adenine glycosylase
MDOR_32740	COG0596	Alpha beta hydrolase
MDOR_32800	COG0542	response to heat
MDOR_32820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MDOR_32840	COG3118	belongs to the thioredoxin family
MDOR_32930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MDOR_32940	COG0302	gtp cyclohydrolase
MDOR_32950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDOR_32990	COG0037	tRNA processing
MDOR_33010	COG2027	D-alanyl-D-alanine carboxypeptidase
MDOR_33020	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MDOR_33040	COG4266	Belongs to the allantoicase family
MDOR_33140	COG0640	Transcriptional regulator
MDOR_33150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MDOR_33220	COG1487	ribonuclease activity
MDOR_33280	COG0470	DNA polymerase III
MDOR_33300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDOR_33300	COG1754	DNA topoisomerase type I activity
MDOR_33320	COG1278	Cold shock
MDOR_33330	COG1205	dead DEAH box helicase
MDOR_33330	COG1111	helicase
MDOR_33430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MDOR_33530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MDOR_33590	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MDOR_33600	COG1408	metallophosphoesterase
MDOR_33610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MDOR_33710	COG1946	Acyl-CoA thioesterase
MDOR_33740	COG2890	protein-(glutamine-N5) methyltransferase activity
MDOR_33780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDOR_33830	COG0714	Associated with various cellular activities
MDOR_33900	COG2837	iron assimilation
MDOR_33990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MDOR_34000	COG0390	transport system, permease component
MDOR_34010	COG1953	Uracil, thiamine, allantoin
MDOR_34020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDOR_34070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDOR_34080	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MDOR_34090	COG0121	glutamine amidotransferase
MDOR_34100	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MDOR_34110	COG3572	ergothioneine biosynthetic process
MDOR_34130	COG1764	response to oxidative stress
MDOR_34210	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDOR_34220	COG2218	PFAM glutamate synthase alpha subunit domain protein
MDOR_34230	COG0069	glutamate synthase activity
MDOR_34280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MDOR_34330	COG0860	N-Acetylmuramoyl-L-alanine amidase
MDOR_34360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MDOR_34380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MDOR_34420	COG1793	dna ligase
MDOR_34440	COG1793	dna ligase
MDOR_34460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDOR_34480	COG0343	queuine tRNA-ribosyltransferase activity
MDOR_34540	COG0590	tRNA wobble adenosine to inosine editing
MDOR_34560	COG0287	Prephenate dehydrogenase
MDOR_34580	COG5416	Lipopolysaccharide assembly protein A domain
MDOR_34610	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_34620	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MDOR_34630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDOR_35080	COG1216	Glycosyl transferase, family 2
MDOR_35140	COG0277	FAD linked oxidase domain protein
MDOR_35150	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_35200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MDOR_35250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MDOR_35260	COG0673	inositol 2-dehydrogenase activity
MDOR_35270	COG1132	(ABC) transporter
MDOR_35300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MDOR_35360	COG1484	DNA-dependent DNA replication
MDOR_35380	COG4584	PFAM Integrase catalytic
MDOR_35420	COG3012	SEC-C Motif Domain Protein
MDOR_35450	COG1408	metallophosphoesterase
MDOR_35460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MDOR_35530	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MDOR_35540	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MDOR_35550	COG0671	phosphoesterase, PA-phosphatase related
MDOR_35560	COG1216	Glycosyl transferase, family 2
MDOR_35600	COG0561	phosphatase activity
MDOR_35620	COG0204	Acyl-transferase
MDOR_35630	COG2146	nitrite reductase [NAD(P)H] activity
MDOR_35630	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MDOR_35780	COG1316	TRANSCRIPTIONal
MDOR_35820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MDOR_35840	COG2119	membrane
MDOR_35900	COG2072	flavoprotein involved in K transport
MDOR_35930	COG1796	DNA polymerase
MDOR_35930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MDOR_35970	COG0070	glutamate synthase
MDOR_35970	COG0069	glutamate synthase activity
MDOR_35970	COG0067	glutamate synthase
MDOR_36010	COG0783	Belongs to the Dps family
MDOR_36120	COG1252	NADH dehydrogenase
MDOR_36140	COG4584	PFAM Integrase catalytic
MDOR_36150	COG1484	DNA-dependent DNA replication
MDOR_36160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDOR_36210	COG2226	methyltransferase
MDOR_36220	COG0438	transferase activity, transferring glycosyl groups
MDOR_36270	COG1335	isochorismatase
MDOR_36300	COG1960	acyl-CoA dehydrogenase activity
MDOR_36310	COG1960	acyl-CoA dehydrogenase activity
MDOR_36330	COG0366	Alpha amylase catalytic
MDOR_36350	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDOR_36410	COG0697	spore germination
MDOR_36430	COG2409	Drug exporters of the RND superfamily
MDOR_36460	COG0705	Rhomboid family
MDOR_36550	COG0714	Associated with various cellular activities
MDOR_36620	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MDOR_36750	COG0492	ferredoxin-NADP+ reductase activity
MDOR_36760	COG1643	Atp-dependent helicase
MDOR_36800	COG1982	Orn Lys Arg decarboxylase major
MDOR_36830	COG2301	Belongs to the HpcH HpaI aldolase family
MDOR_36840	COG1309	transcriptional regulator
MDOR_36880	COG0709	Synthesizes selenophosphate from selenide and ATP
MDOR_36890	COG1921	L-seryl-tRNASec selenium transferase activity
MDOR_36920	COG0437	4 iron, 4 sulfur cluster binding
MDOR_36980	COG0318	PFAM AMP-dependent synthetase and ligase
MDOR_37120	COG1122	ATPase activity
MDOR_37130	COG4721	ABC-type cobalt transport system, permease component
MDOR_37140	COG1960	acyl-CoA dehydrogenase activity
MDOR_37150	COG1960	acyl-CoA dehydrogenase activity
MDOR_37180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MDOR_37190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDOR_37210	COG1937	Protein conserved in bacteria
MDOR_37240	COG2030	dehydratase
MDOR_37260	COG3265	gluconokinase activity
MDOR_37270	COG2610	gluconate transmembrane transporter activity
MDOR_37280	COG3757	hydrolase, family 25
MDOR_37300	COG1309	transcriptional regulator
MDOR_37330	COG0745	RESPONSE REGULATOR receiver
MDOR_37340	COG2205	protein histidine kinase activity
MDOR_37400	COG0431	NADPH-dependent FMN reductase
MDOR_37420	COG2217	Heavy metal translocating P-type atpase
MDOR_37440	COG3344	reverse transcriptase
MDOR_37450	COG3547	Transposase (IS116 IS110 IS902 family)
MDOR_37640	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MDOR_37720	COG0058	SHG alpha-glucan phosphorylase activity
MDOR_37850	COG4584	PFAM Integrase catalytic
MDOR_37860	COG1484	DNA-dependent DNA replication
MDOR_37960	COG0629	single-stranded DNA binding
MDOR_37990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MDOR_38030	COG1260	myo-inositol-1-phosphate synthase
MDOR_38110	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_38150	COG1678	Uncharacterized ACR, COG1678
MDOR_38170	COG0515	serine threonine protein kinase
MDOR_38170	COG2815	serine threonine protein kinase
MDOR_38190	COG0617	tRNA 3'-terminal CCA addition
MDOR_38230	COG1595	DNA-templated transcription, initiation
MDOR_38270	COG3409	Peptidoglycan-binding domain 1 protein
MDOR_38270	COG0860	N-Acetylmuramoyl-L-alanine amidase
MDOR_38300	COG1192	Involved in chromosome partitioning
MDOR_38330	COG0706	membrane insertase activity
MDOR_38340	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MDOR_38380	COG0592	DNA-directed DNA polymerase activity
MDOR_38390	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MDOR_38410	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MDOR_38420	COG0187	DNA topoisomerase II activity
MDOR_38430	COG1372	Participates in initiation and elongation during chromosome replication
MDOR_38430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDOR_38590	COG2815	serine threonine protein kinase
MDOR_38590	COG0515	serine threonine protein kinase
MDOR_38600	COG0515	serine threonine protein kinase
MDOR_38610	COG0768	penicillin binding
MDOR_38640	COG1716	ATPase activity
MDOR_38650	COG1716	ATPase activity
MDOR_38740	COG4584	PFAM Integrase catalytic
MDOR_38750	COG1484	DNA-dependent DNA replication
MDOR_38840	COG2124	cytochrome p450
MDOR_38860	COG3585	molybdate ion transport
MDOR_38890	COG1100	Small GTP-binding protein
MDOR_38990	COG0464	growth
MDOR_39050	COG4842	Belongs to the WXG100 family
MDOR_39060	COG4842	Belongs to the WXG100 family
MDOR_39120	COG1404	Belongs to the peptidase S8 family
MDOR_39180	COG1012	belongs to the aldehyde dehydrogenase family
MDOR_39190	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_39230	COG1960	acyl-CoA dehydrogenase activity
MDOR_39240	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MDOR_39250	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MDOR_39260	COG0300	oxidoreductase activity
MDOR_39290	COG1309	transcriptional regulator
MDOR_39380	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MDOR_39390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MDOR_39440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MDOR_39530	COG2072	flavoprotein involved in K transport
MDOR_39540	COG1960	acyl-CoA dehydrogenase activity
MDOR_39550	COG1960	acyl-CoA dehydrogenase activity
MDOR_39560	COG1960	acyl-CoA dehydrogenase activity
MDOR_39590	COG2072	flavoprotein involved in K transport
MDOR_39600	COG0318	PFAM AMP-dependent synthetase and ligase
MDOR_39610	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_39630	COG0183	Belongs to the thiolase family
MDOR_39660	COG2030	dehydratase
MDOR_39670	COG1960	acyl-CoA dehydrogenase activity
MDOR_39680	COG1028	Short-chain dehydrogenase reductase Sdr
MDOR_39700	COG1960	acyl-CoA dehydrogenase activity
MDOR_39710	COG0318	PFAM AMP-dependent synthetase and ligase