locus-tag	class	description
EGN60_00175	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGN60_00235	COG1187	pseudouridine synthase activity
EGN60_00265	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EGN60_00435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGN60_00575	COG3763	UPF0154 protein
EGN60_00615	COG1481	regulation of sporulation
EGN60_00640	COG0193	aminoacyl-tRNA hydrolase activity
EGN60_00845	COG1323	Belongs to the UPF0348 family
EGN60_00870	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EGN60_00925	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EGN60_00985	COG0556	nucleotide-excision repair
EGN60_01010	COG0194	GDP metabolic process
EGN60_01020	COG0515	serine threonine protein kinase
EGN60_01020	COG2815	serine threonine protein kinase
EGN60_01025	COG1162	GTPase activity
EGN60_01030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGN60_01140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EGN60_01275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGN60_01330	COG0359	binds to the 23S rRNA
EGN60_01360	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGN60_01480	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EGN60_01500	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EGN60_01505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGN60_01595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGN60_01695	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EGN60_01700	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EGN60_01750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EGN60_01775	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGN60_01815	COG1435	thymidine kinase activity
EGN60_01835	COG0813	purine-nucleoside phosphorylase activity
EGN60_01900	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EGN60_01910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EGN60_01945	COG0492	ferredoxin-NADP+ reductase activity
EGN60_02000	COG0254	rRNA binding
EGN60_02010	COG0051	transcription antitermination factor activity, RNA binding
EGN60_02025	COG0089	rRNA binding
EGN60_02040	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EGN60_02055	COG0255	Belongs to the universal ribosomal protein uL29 family
EGN60_02060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGN60_02065	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGN60_02070	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EGN60_02090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EGN60_02095	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EGN60_02100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EGN60_02105	COG0200	Binds to the 23S rRNA
EGN60_02130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGN60_02135	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EGN60_02155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGN60_02205	COG0149	triose-phosphate isomerase activity
EGN60_02245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGN60_02305	COG2001	Belongs to the MraZ family
EGN60_02320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGN60_02440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EGN60_02515	COG2255	four-way junction helicase activity
EGN60_02525	COG0124	histidyl-tRNA synthetase
EGN60_02540	COG0557	exoribonuclease II activity
EGN60_02560	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EGN60_02590	COG1122	ATPase activity
EGN60_02665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGN60_02720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EGN60_02730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGN60_02740	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGN60_02750	COG0228	four-way junction DNA binding
EGN60_02760	COG0335	large ribosomal subunit rRNA binding
EGN60_02780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EGN60_02785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EGN60_02800	COG0222	ribosome binding
EGN60_02805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EGN60_02820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGN60_02835	COG0564	pseudouridine synthase activity
EGN60_02840	COG1739	Uncharacterized protein family UPF0029
EGN60_02950	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGN60_02990	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EGN60_03060	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGN60_03070	COG0360	Binds together with S18 to 16S ribosomal RNA
EGN60_03130	COG0268	Binds directly to 16S ribosomal RNA
EGN60_03140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGN60_03150	COG0470	DNA polymerase III
EGN60_03165	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EGN60_03215	COG0081	regulation of translation