locus-tag	class	description
G7071_00025	ENOG4108RQ5	Beta-lactamase domain-containing protein
G7071_00030	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
G7071_00080	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
G7071_00110	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
G7071_00140	ENOG4108UJU	UPF0301 protein
G7071_00150	ENOG4108Q5F	Tetr family transcriptional regulator
G7071_00160	ENOG4108R5T	secreted protein
G7071_00165	ENOG4105K4H	Nlp p60 protein
G7071_00170	ENOG4105CHR	reductase
G7071_00190	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
G7071_00220	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
G7071_00235	ENOG4105CAK	Cell division ATP-binding protein ftsE
G7071_00245	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
G7071_00375	ENOG4108KPJ	rna polymerase sigma factor
G7071_00395	ENOG4105ETX	regulatoR
G7071_00415	ENOG4105FDF	Could be involved in DNA repair (By similarity)
G7071_00440	ENOG4105C26	Dehydrogenase
G7071_00470	ENOG4105D1F	ATP-binding protein
G7071_00485	ENOG4105C0H	protease
G7071_00495	ENOG4105DU6	RNA polymerase
G7071_00500	ENOG4107ZBN	O-methyltransferase
G7071_00510	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
G7071_00520	ENOG4108UKI	Enoyl-CoA hydratase
G7071_00540	ENOG4108URH	decarboxylase
G7071_00565	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
G7071_00585	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
G7071_00605	ENOG4108Z4U	Ferredoxin
G7071_00630	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
G7071_00635	ENOG4108594	Permease of the drug metabolite transporter
G7071_00685	ENOG4105C3G	gtp-binding protein
G7071_00705	ENOG4105CGK	Exodeoxyribonuclease III
G7071_00720	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
G7071_00725	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
G7071_00735	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G7071_00755	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
G7071_00760	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G7071_00800	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
G7071_00840	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
G7071_00845	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
G7071_00860	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
G7071_00875	ENOG4107GFK	fumarate
G7071_00885	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
G7071_00895	ENOG4105C9Q	fumarate hydratase class II
G7071_00915	ENOG4108IAB	Phoh family
G7071_00920	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
G7071_00930	ENOG4105H67	Protein of unknown function (DUF421)
G7071_00950	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
G7071_00960	ENOG4105E0A	ABC, transporter
G7071_00980	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
G7071_00985	ENOG4105C7B	Threonine dehydratase
G7071_01000	ENOG4105VG5	Membrane
G7071_01010	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
G7071_01085	ENOG4105EET	magnesium chelatase
G7071_01125	ENOG4105K5B	UPF0225 protein
G7071_01155	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G7071_01160	ENOG4105VUC	UPF0237 protein
G7071_01185	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
G7071_01240	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
G7071_01245	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
G7071_01265	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
G7071_01270	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
G7071_01285	ENOG4105CJ1	ABC, transporter
G7071_01320	ENOG4105CEI	nitrite reductase
G7071_01430	ENOG4108I69	Glycosyl transferases group 1
G7071_01445	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
G7071_01460	ENOG4105E0X	reductase
G7071_01465	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
G7071_01470	ENOG4105CKK	Glycosyl transferase, family 2
G7071_01495	ENOG4107JTW	chlorite dismutase
G7071_01530	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
G7071_01540	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
G7071_01565	ENOG4105F95	Monooxygenase
G7071_01585	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
G7071_01615	ENOG4108VCA	G U mismatch-specific DNA glycosylase
G7071_01655	ENOG4105GWZ	Roadblock lc7 family protein
G7071_01695	ENOG4105C3M	thioredoxin reductase
G7071_01750	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
G7071_01790	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G7071_01795	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
G7071_01845	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
G7071_01855	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
G7071_01870	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
G7071_01880	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
G7071_01885	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
G7071_01925	ENOG4105CDA	abc transporter atp-binding protein
G7071_01930	ENOG4105CT1	(ABC) transporter
G7071_01935	ENOG4108Q1T	ABC transporter
G7071_01940	ENOG4105DRP	amino acid AbC transporter
G7071_01960	ENOG4105C5H	ABC transporter
G7071_01970	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
G7071_01975	ENOG4106839	domain protein
G7071_01980	ENOG4105F8V	Hydrolase, tatD family
G7071_02010	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G7071_02015	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G7071_02030	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
G7071_02055	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
G7071_02075	ENOG4105CBG	Sulfatase
G7071_02100	ENOG4105EG6	Saccharopine dehydrogenase
G7071_02130	ENOG4105CG3	alpha amylase, catalytic region
G7071_02145	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
G7071_02165	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
G7071_02195	ENOG4108TGC	Acyltransferase
G7071_02205	ENOG4105P52	geranylgeranyl reductase
G7071_02210	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G7071_02215	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G7071_02220	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G7071_02275	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
G7071_02280	ENOG4108VZM	50s ribosomal protein L10
G7071_02290	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
G7071_02295	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
G7071_02305	ENOG410683Z	Preprotein translocase SecE subunit
G7071_02325	ENOG4107R4N	Cell wall formation (By similarity)
G7071_02335	ENOG410900P	UPF0336 protein
G7071_02340	ENOG410900P	UPF0336 protein
G7071_02345	ENOG4105WDJ	50S ribosomal protein L33
G7071_02360	ENOG4105DV0	amidase (EC 3.5.1.4
G7071_02370	ENOG41067MG	lrgb family
G7071_02395	ENOG4105EUB	pirin domain protein
G7071_02400	ENOG4108MJN	Glycosyl Transferase
G7071_02405	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G7071_02425	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
G7071_02450	ENOG4108VPT	UPF0234 protein
G7071_02455	ENOG4108IJ6	ABC transporter
G7071_02465	ENOG4108I5D	sulfate abc transporter
G7071_02470	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
G7071_02475	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
G7071_02480	ENOG4105DQU	oxidoreductase, subunit beta
G7071_02505	ENOG4105CHP	RNA polymerase
G7071_02520	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7071_02530	ENOG4105D65	subunit l
G7071_02535	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7071_02540	ENOG41087XN	oxidoreductase
G7071_02545	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7071_02550	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
G7071_02570	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7071_02575	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G7071_02580	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7071_02590	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G7071_02600	ENOG4105E4F	Isochorismate synthase
G7071_02620	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
G7071_02625	ENOG4107TCW	O-succinylbenzoate synthase
G7071_02650	ENOG4105HHS	UPF0256 protein
G7071_02660	ENOG4105CRE	cytochrome C
G7071_02665	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
G7071_02670	ENOG4107QIV	Cytochrome c biogenesis protein
G7071_02680	ENOG4108RH7	phosphoglycerate mutase
G7071_02695	ENOG4105D52	delta-aminolevulinic acid dehydratase
G7071_02700	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G7071_02710	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
G7071_02715	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
G7071_02725	ENOG4105CEY	Amp-dependent synthetase and ligase
G7071_02770	ENOG4105II7	pyrroline-5-carboxylate reductase
G7071_02775	ENOG41062BK	proline dehydrogenase
G7071_02785	ENOG4105CJ1	ABC, transporter
G7071_02790	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
G7071_02795	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
G7071_02800	ENOG4107R33	ppx gppa phosphatase
G7071_02805	ENOG4108JWX	
G7071_02825	ENOG4105NAF	rna polymerase sigma factor
G7071_02830	ENOG4105ETE	Transcriptional regulator (LacI family
G7071_02835	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
G7071_02840	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
G7071_02870	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
G7071_02880	ENOG4108IYU	L-aspartate oxidase
G7071_02885	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
G7071_02890	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
G7071_02925	ENOG4105E90	ABC transporter
G7071_02930	ENOG4108IJ8	ABC transporter
G7071_02950	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G7071_02965	ENOG4105EUJ	GTP cyclohydrolase i
G7071_02985	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
G7071_03000	ENOG4105F0N	pyrophosphate phospho-hydrolase
G7071_03005	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G7071_03030	ENOG4108UCS	ABC, transporter
G7071_03035	ENOG4107Z6A	sulfate abc transporter permease
G7071_03090	ENOG4105NHS	Transcriptional regulator, TraR DksA family
G7071_03105	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
G7071_03110	ENOG4105WN5	stage II sporulation protein
G7071_03130	ENOG4108IUE	nitrate reductase beta subunit
G7071_03155	ENOG4105WH1	Two component transcriptional regulator luxr family
G7071_03185	ENOG4107X2D	transcriptional regulator, merr family
G7071_03190	ENOG4105BZU	Histidine kinase
G7071_03210	ENOG4105WH1	Two component transcriptional regulator luxr family
G7071_03215	ENOG4105BZU	Histidine kinase
G7071_03245	ENOG4105CSU	acyl-Coa dehydrogenase
G7071_03250	ENOG4105CSR	polyphosphate kinase 2
G7071_03260	ENOG4105BZU	Histidine kinase
G7071_03275	ENOG4105BZU	Histidine kinase
G7071_03290	ENOG4105I6B	RNA polymerase
G7071_03310	ENOG4105C6E	dna polymerase iii
G7071_03315	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
G7071_03370	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
G7071_03390	ENOG4105D5U	fad dependent oxidoreductase
G7071_03405	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
G7071_03415	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G7071_03420	ENOG4105WN5	stage II sporulation protein
G7071_03475	ENOG4105SHT	UspA domain-containing protein
G7071_03495	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
G7071_03500	ENOG4108MRH	transcriptional regulatory protein
G7071_03520	ENOG4108HRK	Histidine kinase
G7071_03525	ENOG4105DY9	regulatoR
G7071_03585	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G7071_03590	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
G7071_03605	ENOG4105P8F	nudix hydrolase
G7071_03610	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G7071_03615	ENOG4105CSM	endonuclease III
G7071_03625	ENOG4105NAF	rna polymerase sigma factor
G7071_03660	ENOG4105DEN	Luciferase family
G7071_03695	ENOG4105BZ4	penicillin-binding protein
G7071_03730	ENOG4105CFH	Aspartokinase
G7071_03740	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
G7071_03825	ENOG4105HMD	
G7071_03830	ENOG4105D7A	ATP-binding protein
G7071_03845	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
G7071_03850	ENOG4107EFR	Flavocytochrome c
G7071_03885	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G7071_03925	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
G7071_03930	ENOG4105BZU	Histidine kinase
G7071_03935	ENOG4105BZU	Histidine kinase
G7071_03945	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
G7071_04050	ENOG4105BZU	Histidine kinase
G7071_04060	ENOG4108KHK	Glyoxalase Bleomycin resistance protein (Dioxygenase
G7071_04100	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
G7071_04105	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
G7071_04115	ENOG4107T9Q	phosphonate abc transporter
G7071_04120	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
G7071_04135	ENOG4105DP7	Protocatechuate 4,5-dioxygenase
G7071_04140	ENOG41081E8	Alpha beta hydrolase
G7071_04145	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_04150	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_04155	ENOG4105CHU	acetyl-coa acetyltransferase
G7071_04165	ENOG4107QNJ	CoA-transferase subunit B
G7071_04185	ENOG4105CSU	acyl-Coa dehydrogenase
G7071_04195	ENOG4105EYF	MMPL domain protein
G7071_04265	ENOG41080RH	Thioredoxin
G7071_04270	ENOG41065SU	Two-component system sensor kinase
G7071_04295	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
G7071_04335	ENOG4107SIQ	Naphthoate synthase
G7071_04360	ENOG4105VPX	protein, conserved in bacteria
G7071_04375	ENOG4105C5I	Dehydrogenase
G7071_04380	ENOG4105DIA	mandelate racemase muconate lactonizing
G7071_04390	ENOG4105EQX	glucarate dehydratase
G7071_04395	ENOG4105SHT	UspA domain-containing protein
G7071_04415	ENOG4106NZI	LysR family Transcriptional regulator
G7071_04450	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
G7071_04465	ENOG4105D7Z	glutathione synthase
G7071_04480	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
G7071_04500	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_04515	ENOG4105CGD	Nad-dependent epimerase dehydratase
G7071_04525	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G7071_04530	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G7071_04535	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
G7071_04545	ENOG4108Z6B	deaminase
G7071_04565	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
G7071_04575	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
G7071_04600	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
G7071_04610	ENOG4105CIS	alcohol dehydrogenase
G7071_04630	ENOG410667J	hydrolase
G7071_04640	ENOG4108X4Q	Hydrolase
G7071_04645	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
G7071_04665	ENOG4105CQC	Prephenate dehydratase
G7071_04675	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
G7071_04700	ENOG4105CEU	Arginine dihydrolase
G7071_04710	ENOG4108QER	Adenylate cyclase
G7071_04730	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
G7071_04745	ENOG4105WH1	Two component transcriptional regulator luxr family
G7071_04815	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
G7071_04825	ENOG4107QX3	carboxylase
G7071_04835	ENOG4108RZE	Tetr family transcriptional regulator
G7071_04845	ENOG4105C0D	helicase
G7071_04850	ENOG4108V06	Glutathione peroxidase
G7071_04855	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G7071_04865	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G7071_04875	ENOG4108TCJ	secreted hydrolase
G7071_04890	ENOG4105C9K	Endothelin-converting enzyme 1
G7071_04905	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
G7071_04945	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G7071_04950	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
G7071_04960	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
G7071_04975	ENOG4105EM7	Selenocysteine-specific translation elongation factor
G7071_04980	ENOG4105EEF	Alkane 1-monooxygenase
G7071_05000	ENOG4105EYF	MMPL domain protein
G7071_05015	ENOG4108V06	Glutathione peroxidase
G7071_05035	ENOG41068JE	domain protein
G7071_05040	ENOG4105IQC	Inner membrane protein YcfT
G7071_05050	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G7071_05080	ENOG4105HZM	Fha domain containing protein
G7071_05095	ENOG4105CJN	penicillin-binding protein
G7071_05100	ENOG4107TPY	serine threonine protein kinase
G7071_05145	ENOG4105WX6	Membrane
G7071_05160	ENOG41080XP	Cbs domain
G7071_05165	ENOG4108UAJ	Transcriptional regulator
G7071_05190	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7071_05195	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7071_05200	ENOG4105K7N	UPF0232 protein
G7071_05205	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
G7071_05210	ENOG4108J5G	6-phosphogluconate dehydrogenase
G7071_05215	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
G7071_05220	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
G7071_05225	ENOG41084CH	50S ribosomal protein l34
G7071_05230	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
G7071_05235	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
G7071_05240	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
G7071_05245	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
G7071_05250	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
G7071_05255	ENOG4107QJE	Chromosome Partitioning Protein
G7071_05260	ENOG4105FA0	parb-like partition protein
G7071_05280	ENOG4105K63	Thioredoxin
G7071_05285	ENOG4105C3M	thioredoxin reductase
G7071_05315	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
G7071_05330	ENOG4105CZA	synthase
G7071_05340	ENOG4105BZ4	penicillin-binding protein
G7071_05380	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
G7071_05385	ENOG4107YH6	single-stranded DNA-binding protein
G7071_05390	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
G7071_05395	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
G7071_05405	ENOG4107QI1	Mate efflux family protein
G7071_05410	ENOG4105CDU	Replicative dna helicase
G7071_05435	ENOG4108KPJ	rna polymerase sigma factor
G7071_05445	ENOG4107SET	aldo keto reductase
G7071_05485	ENOG4105CPC	Aldo Keto reductase
G7071_05535	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
G7071_05540	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
G7071_05580	ENOG4108UZX	fmn reductase
G7071_05645	ENOG4105CQB	FAD linked oxidase domain protein
G7071_05650	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
G7071_05700	ENOG4107TTQ	Alpha beta hydrolase fold
G7071_05715	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G7071_05735	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
G7071_05750	ENOG4105C1J	atp-dependent rna helicase
G7071_05770	ENOG4108IPT	Naphthoate synthase
G7071_05775	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_05780	ENOG4105CHR	reductase
G7071_05785	ENOG4105CEY	Amp-dependent synthetase and ligase
G7071_05790	ENOG4105CHU	acetyl-coa acetyltransferase
G7071_05795	ENOG4105E39	Enoyl-CoA hydratase
G7071_05800	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G7071_05805	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_05810	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_05825	ENOG4105CHU	acetyl-coa acetyltransferase
G7071_05835	ENOG4105CJ1	ABC, transporter
G7071_05850	ENOG4105W8D	rdd domain containing protein
G7071_05870	ENOG4108RF4	Tetr family transcriptional regulator
G7071_05885	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_05895	ENOG4107QX3	carboxylase
G7071_05955	ENOG4108MMM	RNA Polymerase
G7071_05960	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
G7071_05980	ENOG4105K6V	RNA polymerase
G7071_05995	ENOG4108IPT	Naphthoate synthase
G7071_06010	ENOG4105CBG	Sulfatase
G7071_06030	ENOG4105ETX	regulatoR
G7071_06055	ENOG4105KJF	protein tyrosine phosphatase
G7071_06065	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G7071_06070	ENOG4105CHF	Glutathione S-transferase
G7071_06090	ENOG4105CPP	Dehydrogenase, E1 component
G7071_06095	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
G7071_06100	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
G7071_06105	ENOG4108QIU	Dehydrogenase
G7071_06120	ENOG4105EMN	RNA polymerase sigma factor
G7071_06200	ENOG4105EMU	Dehydrogenase
G7071_06210	ENOG4108S01	response regulator
G7071_06215	ENOG4105BZU	Histidine kinase
G7071_06225	ENOG4108M15	ABC transporter
G7071_06230	ENOG4105CSU	acyl-Coa dehydrogenase
G7071_06235	ENOG410635A	Membrane
G7071_06280	ENOG41090WU	lipolytic protein G-D-S-L family
G7071_06285	ENOG4105DHP	deoxycytidine triphosphate deaminase
G7071_06295	ENOG4105DF6	Fe-S oxidoreductase
G7071_06315	ENOG4105C84	Histidine ammonia-lyase
G7071_06340	ENOG4105CGP	Urocanate hydratase
G7071_06370	ENOG4105CI0	Citrate lyase
G7071_06375	ENOG4105CI0	Citrate lyase
G7071_06400	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
G7071_06425	ENOG4107SM8	Adenylate Guanylate cyclase
G7071_06430	ENOG4105WH1	Two component transcriptional regulator luxr family
G7071_06510	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G7071_06515	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G7071_06550	ENOG4105D7Q	type ii secretion system
G7071_06555	ENOG4107QHF	type ii secretion system protein e
G7071_06560	ENOG4105CZX	twitching motility protein
G7071_06565	ENOG4108VAU	general secretion pathway protein G
G7071_06575	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G7071_06585	ENOG4105CQB	FAD linked oxidase domain protein
G7071_06605	ENOG4105CGD	Nad-dependent epimerase dehydratase
G7071_06625	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
G7071_06630	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
G7071_06675	ENOG4105DK7	lysyl-tRNA synthetase
G7071_06695	ENOG4107TE5	Lipid kinase
G7071_06700	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
G7071_06710	ENOG4105C12	Phosphoribosylglycinamide synthetase
G7071_06715	ENOG4105C83	adenylosuccinate lyase
G7071_06735	ENOG4105C8V	SAICAR synthetase
G7071_06745	ENOG4105CEY	Amp-dependent synthetase and ligase
G7071_06760	ENOG410839H	phosphoribosylformylglycinamidine synthase
G7071_06765	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
G7071_06770	ENOG4105EYF	MMPL domain protein
G7071_06780	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
G7071_06805	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G7071_06815	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
G7071_06855	ENOG41084I6	Protein CrcB homolog
G7071_06860	ENOG41082CG	Protein CrcB homolog
G7071_06900	ENOG4105VEQ	Cold shock protein
G7071_06920	ENOG4105PWN	phosphate abc transporter
G7071_06925	ENOG4105C8U	phosphate abc transporter
G7071_06935	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G7071_06945	ENOG4105CJ3	phosphate transporter
G7071_06955	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
G7071_06965	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
G7071_06970	ENOG41090R7	Ferric uptake
G7071_06975	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
G7071_06980	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
G7071_06985	ENOG4107NHD	transcriptional regulator
G7071_07035	ENOG4108IAJ	Nad-dependent epimerase dehydratase
G7071_07050	ENOG4105KHC	sulfurtransferase
G7071_07055	ENOG4105PKJ	carbohydrate binding
G7071_07085	ENOG4105D75	Capsular exopolysaccharide family
G7071_07120	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G7071_07125	ENOG4105D3Q	Sugar transferase
G7071_07130	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
G7071_07135	ENOG4105CPF	Cell wall formation (By similarity)
G7071_07145	ENOG4105C5E	polysaccharide biosynthesis protein
G7071_07150	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
G7071_07155	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
G7071_07160	ENOG4105CG5	Glycosyl transferase (Group 1
G7071_07165	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G7071_07230	ENOG4107YJ4	chain length determinant protein
G7071_07260	ENOG4107TSN	permease
G7071_07265	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
G7071_07310	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
G7071_07330	ENOG4105D3Q	Sugar transferase
G7071_07335	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
G7071_07340	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
G7071_07345	ENOG4105CMR	udp-glucose 4-epimerase
G7071_07375	ENOG4107R7Y	intracellular protease Pfpi family
G7071_07400	ENOG4105CI3	gtp-binding protein typa
G7071_07405	ENOG4105D4Y	metalloprotease
G7071_07420	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G7071_07425	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
G7071_07435	ENOG4108594	Permease of the drug metabolite transporter
G7071_07445	ENOG4105BZU	Histidine kinase
G7071_07455	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G7071_07470	ENOG4108VJ1	Transcriptional regulator (CarD family
G7071_07490	ENOG4105DQQ	Major facilitator superfamily MFS_1
G7071_07495	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
G7071_07500	ENOG4107QZF	nitrite reductase NADPH large subunit
G7071_07545	ENOG4107QZF	nitrite reductase NADPH large subunit
G7071_07555	ENOG4108YXG	UPF0502 protein
G7071_07560	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
G7071_07580	ENOG4105C8N	cysteinyl-tRNA synthetase
G7071_07605	ENOG4105C0Z	ABC transporter
G7071_07610	ENOG4108IV0	ABC, transporter
G7071_07645	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
G7071_07650	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
G7071_07655	ENOG4105C26	Dehydrogenase
G7071_07660	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
G7071_07665	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
G7071_07700	ENOG4105CBC	glutamate synthase
G7071_07705	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
G7071_07755	ENOG4105NAF	rna polymerase sigma factor
G7071_07765	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
G7071_07790	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G7071_07800	ENOG4105FDP	GntR family transcriptional regulator
G7071_07810	ENOG4105CFI	type iii restriction protein res subunit
G7071_07855	ENOG4105VEQ	Cold shock protein
G7071_07860	ENOG4108N0W	Major Facilitator superfamily
G7071_07880	ENOG4105C7N	Xanthine uracil vitamin C permease
G7071_07885	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
G7071_07890	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
G7071_07895	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
G7071_07905	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
G7071_07930	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G7071_07935	ENOG4108WQ6	secreted protein
G7071_07950	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
G7071_07955	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
G7071_07960	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
G7071_07965	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
G7071_07970	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G7071_07975	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
G7071_07980	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
G7071_07985	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
G7071_07990	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
G7071_08000	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
G7071_08005	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
G7071_08010	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
G7071_08015	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G7071_08020	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
G7071_08025	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
G7071_08030	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
G7071_08035	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
G7071_08040	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
G7071_08045	ENOG410849U	50S ribosomal protein L30
G7071_08050	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
G7071_08060	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
G7071_08100	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G7071_08120	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
G7071_08125	ENOG41067V7	50S ribosomal protein L36
G7071_08135	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
G7071_08145	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G7071_08150	ENOG4108ZT0	50S ribosomal protein l17
G7071_08155	ENOG4105D7K	pfkb domain protein
G7071_08180	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
G7071_08185	ENOG4107Y49	methyltransferase
G7071_08215	ENOG4105C32	Amino acid ABC transporter (Permease)
G7071_08220	ENOG4108IV0	ABC, transporter
G7071_08225	ENOG4105C0Z	ABC transporter
G7071_08230	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
G7071_08235	ENOG4105C0Z	ABC transporter
G7071_08240	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_08245	ENOG4105CC9	acyl-Coa dehydrogenase
G7071_08250	ENOG4105C0H	protease
G7071_08265	ENOG4105BZU	Histidine kinase
G7071_08270	ENOG4105WH1	Two component transcriptional regulator luxr family
G7071_08275	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
G7071_08280	ENOG4108UJD	30S ribosomal protein S9
G7071_08285	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
G7071_08295	ENOG4105CS9	pantothenic acid kinase
G7071_08300	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
G7071_08305	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
G7071_08315	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
G7071_08325	ENOG4108097	ATP-binding protein
G7071_08355	ENOG4105D17	glycoside hydrolase, family 3 domain protein
G7071_08375	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
G7071_08380	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
G7071_08395	ENOG4105CKK	Glycosyl transferase, family 2
G7071_08405	ENOG4108IAJ	Nad-dependent epimerase dehydratase
G7071_08420	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G7071_08440	ENOG4107QVP	Dehydrogenase
G7071_08450	ENOG4105C26	Dehydrogenase
G7071_08460	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G7071_08480	ENOG4105EYF	MMPL domain protein
G7071_08545	ENOG4105D4Y	metalloprotease
G7071_08595	ENOG4105DYW	oxidoreductase
G7071_08600	ENOG4105BZ1	(ABC) transporter
G7071_08605	ENOG4105BZ1	(ABC) transporter
G7071_08630	ENOG4108XG2	Histidine kinase
G7071_08635	ENOG4105WH1	Two component transcriptional regulator luxr family
G7071_08640	ENOG4105CUB	amino acid
G7071_08665	ENOG4105E4C	Lytic transglycosylase catalytic
G7071_08670	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
G7071_08675	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
G7071_08700	ENOG4105DC1	bifunctional purine biosynthesis protein purh
G7071_08710	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
G7071_08720	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
G7071_08735	ENOG4105E9K	Isocitrate dehydrogenase
G7071_08740	ENOG4105F27	Major Facilitator
G7071_08760	ENOG4107H3J	ribonuclease
G7071_08765	ENOG4105E33	succinate dehydrogenase
G7071_08785	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
G7071_08815	ENOG4107RM1	amidohydrolase
G7071_08820	ENOG4105DIH	basic membrane
G7071_08825	ENOG4108JQ9	ABC transporter
G7071_08830	ENOG4105UIB	(ABC) transporter
G7071_08860	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
G7071_08885	ENOG4105C26	Dehydrogenase
G7071_08900	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
G7071_08930	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
G7071_08950	ENOG4105CMR	udp-glucose 4-epimerase
G7071_08990	ENOG41061CK	Antibiotic biosynthesis monooxygenase
G7071_08995	ENOG4105JFG	SpoIID LytB domain protein
G7071_09010	ENOG4108JIK	carboxylase
G7071_09020	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G7071_09035	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_09050	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_09060	ENOG4107WR6	Maf-like protein
G7071_09080	ENOG4105D8K	carboxyl transferase
G7071_09085	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
G7071_09090	ENOG4108QER	Adenylate cyclase
G7071_09095	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7071_09105	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
G7071_09110	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
G7071_09115	ENOG4105K4P	CoA-binding domain protein
G7071_09130	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_09150	ENOG4105CGU	Enoyl-CoA hydratase
G7071_09155	ENOG4108KGH	TRANSCRIPTIONal
G7071_09160	ENOG4108S4H	thioesterase Superfamily protein
G7071_09165	ENOG4108KGH	TRANSCRIPTIONal
G7071_09170	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
G7071_09185	ENOG410602S	Transferase
G7071_09195	ENOG4105EY8	ABC transporter
G7071_09215	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
G7071_09235	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
G7071_09275	ENOG4105W49	UPF0434 protein
G7071_09285	ENOG4105CKW	Inner membrane protein yedI
G7071_09290	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
G7071_09295	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7071_09300	ENOG4105BZU	Histidine kinase
G7071_09305	ENOG4105G3P	Lipoprotein lpqB
G7071_09315	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
G7071_09330	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
G7071_09355	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
G7071_09370	ENOG4105CJW	magnesium transporter
G7071_09420	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_09440	ENOG4105DJG	MaoC domain protein dehydratase
G7071_09460	ENOG4108IXY	short-chain dehydrogenase reductase
G7071_09465	ENOG4107QJE	Chromosome Partitioning Protein
G7071_09480	ENOG4105C1J	atp-dependent rna helicase
G7071_09490	ENOG4105Y3U	Transglycosylase-associated protein
G7071_09500	ENOG4107Z3H	Transcriptional regulator, TetR family
G7071_09525	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
G7071_09530	ENOG4105E09	nadh pyrophosphatase
G7071_09550	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
G7071_09580	ENOG4105DCG	PHP domain protein
G7071_09590	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
G7071_09620	ENOG41063PX	domain protein
G7071_09630	ENOG4105DJZ	UPF0182 protein
G7071_09705	ENOG41088T4	Helicase IV
G7071_09745	ENOG4105DR5	peptidase
G7071_09830	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
G7071_09840	ENOG4105CVR	type I restriction-modification system
G7071_09850	ENOG4105DZR	Type I site-specific deoxyribonuclease
G7071_09860	ENOG4105ESI	atpase involved in dna repair
G7071_09905	ENOG4105PGM	cation diffusion facilitator family transporter
G7071_09930	ENOG41080HT	Transcriptional regulator, arsr family
G7071_09935	ENOG41090EX	DsrE family
G7071_09950	ENOG41082SX	arsR family transcriptional regulator
G7071_09965	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G7071_10000	ENOG4105EYF	MMPL domain protein
G7071_10020	ENOG4108JGH	Tetr family transcriptional regulator
G7071_10070	ENOG41081F0	Precorrin-8x methylmutase
G7071_10085	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
G7071_10090	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
G7071_10100	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
G7071_10105	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G7071_10110	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
G7071_10140	ENOG4108YZT	Adenosylcobinamide kinase
G7071_10150	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G7071_10165	ENOG4105CVJ	phosphoglycerate mutase
G7071_10215	ENOG4107R16	Multicopper oxidase
G7071_10230	ENOG4105EB3	Histidine kinase
G7071_10240	ENOG4105VPX	protein, conserved in bacteria
G7071_10255	ENOG4105C59	p-type ATPase
G7071_10300	ENOG4105E4C	Lytic transglycosylase catalytic
G7071_10355	ENOG4108KQ5	Integrase catalytic subunit
G7071_10365	ENOG4105DQ4	alcohol dehydrogenase
G7071_10450	ENOG4108VYJ	response regulator receiver protein
G7071_10460	ENOG4105BZU	Histidine kinase
G7071_10470	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G7071_10540	ENOG4106NZI	LysR family Transcriptional regulator
G7071_10545	ENOG4105C8Y	Acetylornithine aminotransferase
G7071_10550	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
G7071_10555	ENOG4105C26	Dehydrogenase
G7071_10560	ENOG4105CJP	fad dependent oxidoreductase
G7071_10620	ENOG4105F38	ABC transporter, permease
G7071_10625	ENOG4105D38	putrescine abc transporter
G7071_10630	ENOG4105CI2	imidazolone-5-propionate hydrolase
G7071_10635	ENOG4105C26	Dehydrogenase
G7071_10645	ENOG4105D5P	Methylmalonyl-coA mutase
G7071_10650	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
G7071_10670	ENOG4105EMU	Dehydrogenase
G7071_10675	ENOG41068W2	Cytochrome p-450
G7071_10690	ENOG4105C26	Dehydrogenase
G7071_10750	ENOG4105DXM	phenylacetic acid degradation protein
G7071_10755	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
G7071_10760	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
G7071_10765	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
G7071_10770	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
G7071_10815	ENOG4105CHR	reductase
G7071_10820	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_10825	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
G7071_10840	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
G7071_10845	ENOG4106BRA	Membrane
G7071_10850	ENOG410848D	S4 domain protein YaaA
G7071_10865	ENOG4107TK4	histidinol-phosphate phosphatase
G7071_10880	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
G7071_10890	ENOG4108RAV	Conserved protein
G7071_10900	ENOG4105EMN	RNA polymerase sigma factor
G7071_10905	ENOG4105WMN	AntiSigma factor
G7071_10915	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G7071_10960	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
G7071_10980	ENOG4105C8N	cysteinyl-tRNA synthetase
G7071_11000	ENOG41066YJ	Beta-lactamase
G7071_11005	ENOG4105CB2	alcohol dehydrogenase
G7071_11010	ENOG4105EMU	Dehydrogenase
G7071_11020	ENOG4105EJ2	Transcriptional regulator
G7071_11035	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
G7071_11045	ENOG4108KGH	TRANSCRIPTIONal
G7071_11055	ENOG4105C75	arginyL-tRNA synthetase
G7071_11060	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G7071_11065	ENOG4105D6E	homoserine dehydrogenase
G7071_11070	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
G7071_11075	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
G7071_11085	ENOG4105VFB	Binds the 23S rRNA (By similarity)
G7071_11090	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
G7071_11095	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
G7071_11105	ENOG4105ESV	Glycosyl transferase, family 4
G7071_11120	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
G7071_11125	ENOG4106DE0	ATP synthase
G7071_11130	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
G7071_11135	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G7071_11140	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
G7071_11145	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
G7071_11150	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
G7071_11155	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G7071_11190	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
G7071_11195	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G7071_11200	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G7071_11210	ENOG4105D29	Helix-turn-helix type 11 domain protein
G7071_11220	ENOG4105EV9	Alpha Beta Hydrolase
G7071_11255	ENOG4105CHU	acetyl-coa acetyltransferase
G7071_11290	ENOG4105EYF	MMPL domain protein
G7071_11320	ENOG4105VPX	protein, conserved in bacteria
G7071_11335	ENOG4107TPS	domain protein
G7071_11340	ENOG4108VCT	Sulfite exporter TauE/SafE
G7071_11345	ENOG4105EYF	MMPL domain protein
G7071_11365	ENOG4108594	Permease of the drug metabolite transporter
G7071_11380	ENOG4105E2K	Glycosyl transferase (Group 1
G7071_11385	ENOG4108TJN	glycosyl transferase group 1
G7071_11400	ENOG4107STQ	Multicopper oxidase
G7071_11405	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
G7071_11410	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
G7071_11430	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
G7071_11470	ENOG4105C10	Electron transfer flavoprotein
G7071_11480	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
G7071_11490	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
G7071_11495	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
G7071_11525	ENOG41085FC	arsR family transcriptional regulator
G7071_11540	ENOG4105CHR	reductase
G7071_11550	ENOG4105C8T	Leucyl-tRNA synthetase
G7071_11555	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
G7071_11565	ENOG4105EPR	degv family
G7071_11570	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
G7071_11585	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
G7071_11605	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
G7071_11610	ENOG41090B9	response to stress
G7071_11645	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
G7071_11665	ENOG4107YU2	histidine triad (hIT) protein
G7071_11670	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G7071_11680	ENOG4105C0Z	ABC transporter
G7071_11685	ENOG4108IQE	Amp-dependent synthetase and ligase
G7071_11695	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
G7071_11705	ENOG4108IV0	ABC, transporter
G7071_11725	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
G7071_11745	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
G7071_11755	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
G7071_11760	ENOG4105WQG	acetyltransferase
G7071_11795	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G7071_11800	ENOG4108J2P	Alpha beta hydrolase fold
G7071_11805	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
G7071_11810	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
G7071_11825	ENOG4105DIK	(ABC) transporter
G7071_11830	ENOG4105DSE	periplasmic solute binding protein
G7071_11840	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
G7071_11860	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
G7071_11900	ENOG4105TVB	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
G7071_11905	ENOG4107W19	lmbE family
G7071_11920	ENOG4105VTR	Integrase
G7071_11990	ENOG4105D9P	serine threonine protein kinase
G7071_12020	ENOG4108J2P	Alpha beta hydrolase fold
G7071_12040	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G7071_12045	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
G7071_12050	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
G7071_12080	ENOG4105CEY	Amp-dependent synthetase and ligase
G7071_12105	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7071_12110	ENOG41062D9	Histidine kinase
G7071_12135	ENOG4107XFJ	UPF0246 protein
G7071_12140	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
G7071_12170	ENOG4105D8V	Glucose sorbosone dehydrogenase
G7071_12190	ENOG4108DWA	Nad synthetase
G7071_12200	ENOG4105C5F	glutamine synthetase
G7071_12205	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
G7071_12225	ENOG4105K70	DNA-binding protein
G7071_12255	ENOG4105H3G	oxidoreductase
G7071_12280	ENOG4105ESP	cell wall surface anchor family protein
G7071_12295	ENOG4105BZU	Histidine kinase
G7071_12345	ENOG410870F	Cyclic nucleotide-binding protein
G7071_12355	ENOG4108QMY	dioxygenase
G7071_12360	ENOG4105DTQ	mandelate racemase muconate lactonizing
G7071_12365	ENOG4107RSM	transcriptional regulator
G7071_12370	ENOG4105CSH	Transporter
G7071_12390	ENOG4105F2Z	3-oxoadipate enol-lactonase
G7071_12395	ENOG4105CHU	acetyl-coa acetyltransferase
G7071_12400	ENOG4107RSM	transcriptional regulator
G7071_12410	ENOG41062FI	Regulatory protein, PpaA
G7071_12430	ENOG4107S2Z	UPF0761 membrane protein
G7071_12435	ENOG4105EXC	Acyl-transferase
G7071_12440	ENOG4105DIM	ABC transporter
G7071_12445	ENOG4105CIG	ABC transporter
G7071_12450	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
G7071_12455	ENOG4105DYW	oxidoreductase
G7071_12465	ENOG4105MXW	flavin reductase domain protein, FMN-binding
G7071_12470	ENOG41088PD	hydrolase
G7071_12475	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
G7071_12495	ENOG4107EFR	Flavocytochrome c
G7071_12500	ENOG4106517	Short-chain dehydrogenase reductase Sdr
G7071_12505	ENOG4108QIU	Dehydrogenase
G7071_12525	ENOG4108JQ1	Dehydrogenase
G7071_12610	ENOG4105F2C	Acetyl-CoA acetyltransferase
G7071_12635	ENOG4105J5T	Amp-dependent synthetase and ligase
G7071_12640	ENOG4105J5T	Amp-dependent synthetase and ligase
G7071_12675	ENOG4108KC1	acyl-Coa dehydrogenase
G7071_12685	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
G7071_12690	ENOG4105CEY	Amp-dependent synthetase and ligase
G7071_12695	ENOG4105CHR	reductase
G7071_12705	ENOG4105DEF	Extracellular solute-binding protein, family 5
G7071_12720	ENOG4105C3U	ABC transporter
G7071_12725	ENOG4108JQ7	(ABC) transporter
G7071_12760	ENOG4105E1F	short-chain dehydrogenase reductase
G7071_12765	ENOG4105DEF	Extracellular solute-binding protein, family 5
G7071_12775	ENOG4105X7H	acyl-CoA dehydrogenase
G7071_12785	ENOG4108KC2	acyl-Coa dehydrogenase
G7071_12795	ENOG4105CHU	acetyl-coa acetyltransferase
G7071_12815	ENOG4105CS1	NAD(P)H quinone oxidoreductase
G7071_12840	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
G7071_12845	ENOG4108JJB	ABC transporter
G7071_12850	ENOG4105CHU	acetyl-coa acetyltransferase
G7071_12860	ENOG4107ZYJ	bioY protein
G7071_12900	ENOG4105C32	Amino acid ABC transporter (Permease)
G7071_12910	ENOG4105C0Z	ABC transporter
G7071_12915	ENOG4108IV0	ABC, transporter
G7071_12930	ENOG4108IJ2	phosphate acetyltransferase
G7071_12935	ENOG4107QX3	carboxylase
G7071_12970	ENOG4105CHU	acetyl-coa acetyltransferase
G7071_13000	ENOG41073TP	transcriptional regulator
G7071_13010	ENOG4105C26	Dehydrogenase
G7071_13015	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
G7071_13020	ENOG4108Z86	Glutamine amidotransferase
G7071_13025	ENOG4105C5F	glutamine synthetase
G7071_13050	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
G7071_13060	ENOG4105CJ1	ABC, transporter
G7071_13065	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
G7071_13095	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
G7071_13110	ENOG4105JAB	phenazine biosynthesis protein, phzf family
G7071_13115	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
G7071_13150	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G7071_13155	ENOG4105CN5	Metallo-Beta-Lactamase
G7071_13165	ENOG4107QZI	cell division protein FtsK
G7071_13175	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
G7071_13190	ENOG4105BZP	glycoside hydrolase 15-related
G7071_13195	ENOG4105CEV	competence damage-inducible protein
G7071_13200	ENOG4105WBV	Transcriptional regulator
G7071_13205	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
G7071_13210	ENOG4107QRT	dEAD DEAH box helicase
G7071_13215	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
G7071_13220	ENOG4108176	endoribonuclease L-psp
G7071_13255	ENOG4105DXI	Major Facilitator superfamily
G7071_13260	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
G7071_13275	ENOG4105CSR	polyphosphate kinase 2
G7071_13295	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
G7071_13305	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
G7071_13310	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
G7071_13315	ENOG4105BZU	Histidine kinase
G7071_13320	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
G7071_13325	ENOG4105CSU	acyl-Coa dehydrogenase
G7071_13350	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
G7071_13380	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
G7071_13400	ENOG4105DK0	Indole-3-glycerol phosphate synthase
G7071_13405	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G7071_13410	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
G7071_13420	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
G7071_13425	ENOG4105CBC	glutamate synthase
G7071_13435	ENOG4105CA9	Pyruvate kinase
G7071_13455	ENOG4105CP9	extracellular ligand-binding receptor
G7071_13465	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
G7071_13470	ENOG4105C0Z	ABC transporter
G7071_13475	ENOG4108IV0	ABC, transporter
G7071_13480	ENOG4105CDA	abc transporter atp-binding protein
G7071_13485	ENOG4105EAD	ABC transporter
G7071_13490	ENOG4107R0W	ABC transporter
G7071_13525	ENOG4108I69	Glycosyl transferases group 1
G7071_13535	ENOG41073B4	coagulation factor 5 8 type domain-containing protein
G7071_13555	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G7071_13560	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
G7071_13570	ENOG4107F3J	Amp-dependent synthetase and ligase
G7071_13580	ENOG4105XT2	Transcriptional regulator
G7071_13595	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
G7071_13615	ENOG4105E7W	lamb ycsf family protein
G7071_13625	ENOG4107R7A	Allophanate hydrolase subunit 2
G7071_13630	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G7071_13650	ENOG4105SHT	UspA domain-containing protein
G7071_13695	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7071_13720	ENOG4107UWP	Major facilitator superfamily MFS_1
G7071_13730	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7071_13760	ENOG4107W53	thymidine kinase
G7071_13770	ENOG4105PDP	Short chain dehydrogenase
G7071_13780	ENOG4105EN6	Membrane
G7071_13790	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
G7071_13815	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
G7071_13840	ENOG4107VEG	TrkA-N domain protein
G7071_13845	ENOG4105C0X	amino acid
G7071_13850	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
G7071_13915	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
G7071_13920	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
G7071_13925	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
G7071_13940	ENOG4105C8J	)-transporter
G7071_13955	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G7071_13960	ENOG4105CHU	acetyl-coa acetyltransferase
G7071_13970	ENOG4105C29	acyl-CoA thioesterase
G7071_13985	ENOG4105CHR	reductase
G7071_13990	ENOG4105CHU	acetyl-coa acetyltransferase
G7071_13995	ENOG4105D9P	serine threonine protein kinase
G7071_14000	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
G7071_14005	ENOG4105CXT	aspartate transcarbamylase
G7071_14010	ENOG4105CD3	dihydroorotase
G7071_14020	ENOG4105CYC	Transferase
G7071_14030	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
G7071_14035	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
G7071_14040	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
G7071_14050	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
G7071_14055	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
G7071_14070	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
G7071_14075	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
G7071_14085	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
G7071_14090	ENOG4107RSZ	Primosomal protein n'
G7071_14100	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G7071_14105	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
G7071_14135	ENOG4105DJV	ribulose-phosphate 3-epimerase
G7071_14155	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G7071_14160	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
G7071_14165	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
G7071_14170	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
G7071_14205	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
G7071_14210	ENOG41084BS	50S ribosomal protein L35
G7071_14215	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
G7071_14220	ENOG4108RWN	rrna methyltransferase
G7071_14225	ENOG4105BZU	Histidine kinase
G7071_14235	ENOG4105BZU	Histidine kinase
G7071_14240	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7071_14245	ENOG4105EB3	Histidine kinase
G7071_14250	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
G7071_14265	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
G7071_14275	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
G7071_14280	ENOG4105CAS	nag kinase
G7071_14285	ENOG4105C8Y	Acetylornithine aminotransferase
G7071_14290	ENOG4105DBV	ornithine carbamoyltransferase
G7071_14295	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
G7071_14300	ENOG4105CDH	Citrulline--aspartate ligase
G7071_14305	ENOG4105CH7	arginosuccinase
G7071_14310	ENOG4108VX5	3-methyladenine DNA glycosylase
G7071_14340	ENOG4105DSU	hydrolase
G7071_14355	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
G7071_14360	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
G7071_14375	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
G7071_14385	ENOG4108YZ4	nudix hydrolase
G7071_14390	ENOG4105DCF	alanine dehydrogenase
G7071_14420	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
G7071_14430	ENOG4105KHN	chorismate mutase
G7071_14440	ENOG4105CAT	Cytidine monophosphate kinase
G7071_14445	ENOG4105F6E	Acyl-transferase
G7071_14455	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
G7071_14460	ENOG4105E4C	Lytic transglycosylase catalytic
G7071_14470	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
G7071_14475	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
G7071_14485	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
G7071_14495	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G7071_14505	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
G7071_14510	ENOG4105EHG	Permease protein
G7071_14515	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
G7071_14520	ENOG4107QZB	decarboxylase
G7071_14525	ENOG4105CVJ	phosphoglycerate mutase
G7071_14530	ENOG4105DU1	integral membrane protein, terc
G7071_14545	ENOG4105CBG	Sulfatase
G7071_14550	ENOG4105C37	(CBS) domain
G7071_14585	ENOG4108UW8	fha domain-containing protein
G7071_14620	ENOG4105EYH	Exonuclease
G7071_14625	ENOG4107RH8	nuclease SbcCD subunit D
G7071_14630	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
G7071_14665	ENOG41060BG	Tetr family transcriptional regulator
G7071_14675	ENOG4105C6X	Major Facilitator
G7071_14685	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G7071_14710	ENOG41082BM	Transcriptional regulator, arsr family
G7071_14750	ENOG4105Q70	
G7071_14760	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
G7071_14770	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
G7071_14780	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
G7071_14785	ENOG4105FRY	Dehydrogenase
G7071_14800	ENOG4105J0Q	Transcriptional regulator
G7071_14805	ENOG4105HFS	5'-3' exonuclease
G7071_14835	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
G7071_14840	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
G7071_14845	ENOG4107TMB	Transcriptional regulator
G7071_14860	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
G7071_14865	ENOG4108UDB	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
G7071_14875	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
G7071_14880	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
G7071_14885	ENOG4105VC4	domain protein
G7071_14890	ENOG4105E5F	proteasome
G7071_14895	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G7071_14900	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
G7071_14905	ENOG4105RHY	Pfam:UPF0157
G7071_14925	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
G7071_14955	ENOG4105C3R	Methionine synthase
G7071_14965	ENOG4105C8N	cysteinyl-tRNA synthetase
G7071_14985	ENOG4105D7N	magnesium and cobalt transport protein CorA
G7071_14995	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
G7071_15000	ENOG4105CPC	Aldo Keto reductase
G7071_15025	ENOG41088YS	Glycosyl transferase (Group 1
G7071_15065	ENOG4105BZU	Histidine kinase
G7071_15080	ENOG4105VEQ	Cold shock protein
G7071_15085	ENOG4108J2P	Alpha beta hydrolase fold
G7071_15110	ENOG4106F1P	AAA ATPase, central domain protein
G7071_15120	ENOG4105CT1	(ABC) transporter
G7071_15145	ENOG4105HZM	Fha domain containing protein
G7071_15170	ENOG4105DY8	decarboxylase
G7071_15185	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_15195	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G7071_15210	ENOG4108V1U	phospholipid-binding protein
G7071_15260	ENOG4105DKW	ABC transporter
G7071_15270	ENOG4105EAC	phosphoserine phosphatase
G7071_15285	ENOG4105CHR	reductase
G7071_15290	ENOG4105WKW	Pfam:DUF1458
G7071_15305	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G7071_15370	ENOG4105BZ1	(ABC) transporter
G7071_15375	ENOG4105E39	Enoyl-CoA hydratase
G7071_15385	ENOG4105C5H	ABC transporter
G7071_15415	ENOG4105VG1	fes assembly suf system protein
G7071_15420	ENOG4108UNV	SUF system FeS assembly protein, NifU family
G7071_15425	ENOG4105C9B	Cysteine desulfurase
G7071_15430	ENOG4105C3K	feS assembly ATPase SufC
G7071_15440	ENOG4105JRK	feS assembly protein SufD
G7071_15445	ENOG4105DIW	FeS assembly protein SUFB
G7071_15485	ENOG4105CJ1	ABC, transporter
G7071_15500	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
G7071_15510	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
G7071_15530	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
G7071_15550	ENOG4105CP7	Triose-phosphate isomerase
G7071_15555	ENOG4105BZA	Phosphoglycerate kinase
G7071_15560	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G7071_15565	ENOG4105CIE	May be required for sporulation (By similarity)
G7071_15575	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
G7071_15580	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
G7071_15590	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G7071_15605	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
G7071_15625	ENOG4105CNG	UPF0061 protein
G7071_15640	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
G7071_15700	ENOG4105X7H	acyl-CoA dehydrogenase
G7071_15705	ENOG4108KC2	acyl-Coa dehydrogenase
G7071_15725	ENOG4106YT9	Enoyl-CoA hydratase
G7071_15730	ENOG41080RH	Thioredoxin
G7071_15740	ENOG4105CEY	Amp-dependent synthetase and ligase
G7071_15745	ENOG4105E5G	Alpha beta hydrolase fold
G7071_15750	ENOG4105DYW	oxidoreductase
G7071_15770	ENOG4106A3M	Cytochrome p-450
G7071_15775	ENOG4105F2C	Acetyl-CoA acetyltransferase
G7071_15780	ENOG4105C1G	acyl-Coa dehydrogenase
G7071_15785	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
G7071_15820	ENOG4105DGW	oligopeptidase A
G7071_15825	ENOG4105CGD	Nad-dependent epimerase dehydratase
G7071_15835	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
G7071_15845	ENOG41060WC	Enoyl-CoA hydratase
G7071_15875	ENOG4105CBG	Sulfatase
G7071_15885	ENOG4105F2C	Acetyl-CoA acetyltransferase
G7071_15890	ENOG4108RZE	Tetr family transcriptional regulator
G7071_15900	ENOG4105CC9	acyl-Coa dehydrogenase
G7071_15905	ENOG4105CEY	Amp-dependent synthetase and ligase
G7071_15910	ENOG4105CC9	acyl-Coa dehydrogenase
G7071_15915	ENOG4105D2B	acyl-CoA dehydrogenase
G7071_15920	ENOG4105D2B	acyl-CoA dehydrogenase
G7071_15935	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
G7071_15940	ENOG41088PD	hydrolase
G7071_15945	ENOG4108KC1	acyl-Coa dehydrogenase
G7071_15955	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
G7071_15960	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
G7071_15965	ENOG4105IKQ	hydratase
G7071_15970	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
G7071_16000	ENOG4105X7H	acyl-CoA dehydrogenase
G7071_16020	ENOG4105D2B	acyl-CoA dehydrogenase
G7071_16040	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
G7071_16045	ENOG4108SGK	Tetr family transcriptional regulator
G7071_16055	ENOG4105CHR	reductase
G7071_16065	ENOG4105CAY	ferredoxin--nadp reductase
G7071_16120	ENOG4105H0Z	Hemerythrin HHE cation binding domain protein
G7071_16125	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
G7071_16130	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
G7071_16140	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
G7071_16155	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
G7071_16165	ENOG4107QN2	dihydrolipoyl dehydrogenase
G7071_16170	ENOG4108TM9	integral membrane protein
G7071_16175	ENOG410803B	Involved in the transcription termination process (By similarity)
G7071_16180	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G7071_16200	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
G7071_16205	ENOG4105D49	3-dehydroquinate synthase
G7071_16210	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
G7071_16215	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
G7071_16225	ENOG4105E2X	shikimate dehydrogenase
G7071_16235	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
G7071_16240	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G7071_16265	ENOG4108JQ7	(ABC) transporter
G7071_16270	ENOG4105C3U	ABC transporter
G7071_16285	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G7071_16305	ENOG4105CUT	histidyl-tRNA synthetase
G7071_16315	ENOG4105C99	atpase involved in dna repair
G7071_16320	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G7071_16325	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
G7071_16330	ENOG4105VIE	preprotein translocase, subunit YajC
G7071_16335	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G7071_16340	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
G7071_16345	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
G7071_16350	ENOG4105CDY	transcriptional regulatory protein
G7071_16355	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
G7071_16390	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
G7071_16405	ENOG4107TK4	histidinol-phosphate phosphatase
G7071_16425	ENOG4105C22	threonyL-tRNA synthetase
G7071_16435	ENOG4105BZ1	(ABC) transporter
G7071_16440	ENOG4107XWI	flavin reductase domain protein, FMN-binding
G7071_16465	ENOG4105C26	Dehydrogenase
G7071_16480	ENOG4108YV4	Universal stress protein
G7071_16485	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G7071_16495	ENOG4105EJ5	oxidoreductase gamma subunit
G7071_16500	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
G7071_16505	ENOG4105DDK	oxidoreductase, beta subunit
G7071_16510	ENOG4105BZ8	glutamate synthase
G7071_16525	ENOG4105CAQ	asparagine synthetase
G7071_16565	ENOG4105BZ1	(ABC) transporter
G7071_16570	ENOG4105BZ1	(ABC) transporter
G7071_16575	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
G7071_16580	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
G7071_16585	ENOG4108VQT	Alpha beta hydrolase fold protein
G7071_16590	ENOG4105KV4	Transcriptional regulator
G7071_16610	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
G7071_16615	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
G7071_16620	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G7071_16625	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
G7071_16640	ENOG4105C0B	DNA polymerase III (alpha subunit)
G7071_16665	ENOG4105SCY	DNAK suppressor
G7071_16680	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
G7071_16685	ENOG4105DFA	alanine racemase domain protein
G7071_16690	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
G7071_16700	ENOG4108UFP	Essential cell division protein (By similarity)
G7071_16705	ENOG4105DFU	Cell wall formation (By similarity)
G7071_16710	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
G7071_16720	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
G7071_16725	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
G7071_16735	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
G7071_16740	ENOG4105CJN	penicillin-binding protein
G7071_16750	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
G7071_16760	ENOG4108V6E	Cell division protein mraZ
G7071_16765	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G7071_16785	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G7071_16795	ENOG4105C0B	DNA polymerase III (alpha subunit)
G7071_16820	ENOG4108222	arsenate reductase
G7071_16830	ENOG4107VFM	Dehydrogenase
G7071_16870	ENOG4105KYH	transcriptional regulatory protein
G7071_16875	ENOG4105E4C	Lytic transglycosylase catalytic
G7071_16905	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
G7071_16945	ENOG4105WH1	Two component transcriptional regulator luxr family
G7071_16980	ENOG4105DKQ	ROK family
G7071_17045	ENOG4105ENE	Histidine kinase
G7071_17080	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
G7071_17130	ENOG4107S1N	anthranilate phosphoribosyltransferase
G7071_17145	ENOG4105CCU	oxidase (Subunit III)
G7071_17150	ENOG4107UDY	cytochrome C
G7071_17155	ENOG4107EUI	c reductase, iron-sulfur
G7071_17160	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G7071_17175	ENOG4108ZRS	Part of cytochrome c oxidase, its function is
G7071_17185	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
G7071_17190	ENOG4107QI6	Cysteine desulfurase
G7071_17200	ENOG4107T4Z	adenosine kinase
G7071_17225	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
G7071_17230	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
G7071_17240	ENOG4105D0M	Protease HtpX homolog
G7071_17290	ENOG4105C1V	Peptidase, M16
G7071_17295	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
G7071_17300	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
G7071_17320	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
G7071_17325	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G7071_17330	ENOG4105E98	transcriptional regulator DeoR family
G7071_17340	ENOG4105DM4	PTS System
G7071_17345	ENOG4105KZ7	phosphocarrier protein hpr
G7071_17365	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
G7071_17370	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
G7071_17375	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
G7071_17390	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
G7071_17425	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
G7071_17430	ENOG4105DZP	Membrane-associated zinc metalloprotease
G7071_17475	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
G7071_17490	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
G7071_17495	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
G7071_17500	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
G7071_17505	ENOG4105CE9	30S ribosomal protein S2
G7071_17530	ENOG41080R2	UPF0102 protein
G7071_17540	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G7071_17545	ENOG4107QYR	Signal peptidase i
G7071_17550	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
G7071_17555	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
G7071_17560	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
G7071_17565	ENOG41082KU	UPF0109 protein
G7071_17570	ENOG4105K5M	30s ribosomal protein S16
G7071_17615	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
G7071_17640	ENOG4105H63	Glycosyl transferase, family 2
G7071_17700	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
G7071_17705	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
G7071_17710	ENOG41084BZ	50S ribosomal protein L32
G7071_17720	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
G7071_17735	ENOG4105DP4	dak2 domain fusion protein ylov
G7071_17740	ENOG4105VB9	50S ribosomal protein l28
G7071_17770	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
G7071_17785	ENOG4105K70	DNA-binding protein
G7071_17790	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G7071_17805	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
G7071_17830	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
G7071_17870	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
G7071_17880	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G7071_17885	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
G7071_17895	ENOG4108YYH	Nadph-dependent fmn reductase
G7071_17910	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G7071_17915	ENOG4105BZU	Histidine kinase
G7071_17925	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
G7071_17930	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G7071_17935	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G7071_17960	ENOG4108VW9	Membrane
G7071_17970	ENOG4108JQ1	Dehydrogenase
G7071_17975	ENOG4107ZXU	DSBA oxidoreductase
G7071_17985	ENOG4105CJ1	ABC, transporter
G7071_17995	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
G7071_18010	ENOG4105KZX	Pterin carbinolamine dehydratase
G7071_18025	ENOG4105C01	Dihydroxy-acid dehydratase
G7071_18060	ENOG4105BZ1	(ABC) transporter
G7071_18080	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G7071_18085	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G7071_18090	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G7071_18095	ENOG4105NAF	rna polymerase sigma factor
G7071_18120	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G7071_18125	ENOG4108JGH	Tetr family transcriptional regulator
G7071_18145	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
G7071_18160	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
G7071_18165	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G7071_18170	ENOG4105K46	50S ribosomal protein l27
G7071_18175	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
G7071_18180	ENOG4105C03	ribonuclease
G7071_18195	ENOG4108RJ9	Glycosyl transferase, family 2
G7071_18275	ENOG4105BZU	Histidine kinase
G7071_18280	ENOG4105CNI	cell division protein FtsW
G7071_18285	ENOG4105CJN	penicillin-binding protein
G7071_18300	ENOG4105DFF	Rod shape-determining protein mreb
G7071_18310	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
G7071_18320	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
G7071_18330	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
G7071_18340	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
G7071_18345	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G7071_18350	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G7071_18365	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
G7071_18390	ENOG4108YZG	isomerase
G7071_18410	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
G7071_18420	ENOG4105MC2	DSBA oxidoreductase
G7071_18450	ENOG4108Z9K	Osmotically inducible protein
G7071_18460	ENOG4108TGP	Thioesterase superfamily protein
G7071_18475	ENOG4105CHU	acetyl-coa acetyltransferase
G7071_18510	ENOG4107T6F	Xaa-Pro aminopeptidase
G7071_18515	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
G7071_18525	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
G7071_18545	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
G7071_18560	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
G7071_18590	ENOG4105CAY	ferredoxin--nadp reductase
G7071_18600	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
G7071_18610	ENOG4108JJB	ABC transporter
G7071_18645	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
G7071_18650	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)