locus-tag	class	description
G7071_00025	COG1234	tRNA 3'-trailer cleavage
G7071_00030	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G7071_00080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G7071_00110	COG3185	4-Hydroxyphenylpyruvate dioxygenase
G7071_00140	COG1678	Uncharacterized ACR, COG1678
G7071_00150	COG1309	transcriptional regulator
G7071_00160	COG1470	cell adhesion involved in biofilm formation
G7071_00165	COG0791	NLP P60 protein
G7071_00165	COG0741	lytic transglycosylase activity
G7071_00170	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_00190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7071_00220	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G7071_00235	COG2884	Cell division ATP-binding protein ftsE
G7071_00245	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G7071_00375	COG1595	DNA-templated transcription, initiation
G7071_00395	COG0745	RESPONSE REGULATOR receiver
G7071_00415	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G7071_00440	COG1012	belongs to the aldehyde dehydrogenase family
G7071_00470	COG0489	protein tyrosine kinase activity
G7071_00485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7071_00495	COG1595	DNA-templated transcription, initiation
G7071_00510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G7071_00520	COG1024	Enoyl-CoA hydratase
G7071_00540	COG1611	Belongs to the LOG family
G7071_00565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G7071_00575	COG2318	DinB family
G7071_00585	COG2171	N-acyltransferase activity
G7071_00615	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G7071_00630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G7071_00685	COG0012	GTP binding
G7071_00705	COG0708	Exodeoxyribonuclease III
G7071_00710	COG1322	Protein conserved in bacteria
G7071_00720	COG0009	L-threonylcarbamoyladenylate synthase
G7071_00725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G7071_00735	COG1722	exodeoxyribonuclease VII activity
G7071_00755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G7071_00760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7071_00800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G7071_00835	COG0351	phosphomethylpyrimidine kinase
G7071_00840	COG0352	thiamine-phosphate diphosphorylase activity
G7071_00845	COG2022	thiamine diphosphate biosynthetic process
G7071_00860	COG0352	thiamine-phosphate diphosphorylase activity
G7071_00860	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
G7071_00875	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
G7071_00875	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G7071_00885	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G7071_00895	COG0114	fumarate hydratase activity
G7071_00915	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G7071_00920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G7071_00930	COG2323	membrane
G7071_00960	COG1120	ATPase activity
G7071_00980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7071_00985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G7071_01000	COG2149	membrane
G7071_01010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7071_01070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G7071_01085	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
G7071_01125	COG3012	SEC-C Motif Domain Protein
G7071_01155	COG0242	peptide deformylase activity
G7071_01160	COG3830	Belongs to the UPF0237 family
G7071_01185	COG0148	phosphopyruvate hydratase activity
G7071_01240	COG0193	aminoacyl-tRNA hydrolase activity
G7071_01245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G7071_01265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G7071_01270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G7071_01285	COG1131	(ABC) transporter
G7071_01420	COG1793	dna ligase
G7071_01430	COG0438	transferase activity, transferring glycosyl groups
G7071_01445	COG2130	NADP-dependent
G7071_01460	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7071_01465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G7071_01470	COG0463	Glycosyl transferase, family 2
G7071_01530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G7071_01540	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G7071_01565	COG2072	flavoprotein involved in K transport
G7071_01585	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G7071_01590	COG4129	membrane
G7071_01630	COG0387	Pfam Sodium calcium exchanger
G7071_01655	COG2018	Roadblock/LC7 domain
G7071_01695	COG0492	ferredoxin-NADP+ reductase activity
G7071_01750	COG1619	proteins homologs of microcin C7 resistance protein MccF
G7071_01790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7071_01795	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G7071_01845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G7071_01855	COG2249	NAD(P)H dehydrogenase (quinone) activity
G7071_01870	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G7071_01880	COG0405	Gamma-glutamyltransferase
G7071_01885	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G7071_01925	COG1126	abc transporter atp-binding protein
G7071_01930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7071_01935	COG0765	amino acid transport
G7071_01940	COG0765	amino acid transport
G7071_01960	COG0488	(ABC) transporter
G7071_01970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G7071_01975	COG3583	domain protein
G7071_01980	COG0084	hydrolase, TatD family'
G7071_02010	COG0315	cyclic pyranopterin monophosphate synthase activity
G7071_02010	COG0521	Mo-molybdopterin cofactor biosynthetic process
G7071_02015	COG0315	cyclic pyranopterin monophosphate synthase activity
G7071_02030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G7071_02055	COG1970	mechanosensitive ion channel activity
G7071_02075	COG3119	arylsulfatase activity
G7071_02100	COG3268	Saccharopine dehydrogenase
G7071_02130	COG0366	Alpha amylase catalytic
G7071_02140	COG2814	Major facilitator Superfamily
G7071_02145	COG0259	pyridoxamine-phosphate oxidase activity
G7071_02165	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G7071_02195	COG3594	Acyltransferase
G7071_02205	COG0644	oxidoreductase
G7071_02210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G7071_02215	COG0085	RNA polymerase activity
G7071_02260	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G7071_02265	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G7071_02275	COG0222	ribosome binding
G7071_02280	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G7071_02290	COG0081	regulation of translation
G7071_02295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G7071_02315	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G7071_02325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G7071_02335	COG2030	dehydratase
G7071_02340	COG2030	dehydratase
G7071_02345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G7071_02360	COG0154	amidase activity
G7071_02370	COG1346	cytolysis
G7071_02400	COG0438	transferase activity, transferring glycosyl groups
G7071_02405	COG1902	pentaerythritol trinitrate reductase activity
G7071_02425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G7071_02450	COG1666	GTP binding
G7071_02455	COG3842	ATPase activity
G7071_02465	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G7071_02470	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G7071_02475	COG0674	pyruvate-flavodoxin oxidoreductase activity
G7071_02475	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G7071_02480	COG1013	pyruvate-flavodoxin oxidoreductase activity
G7071_02505	COG4941	Belongs to the sigma-70 factor family
G7071_02520	COG1007	ATP synthesis coupled electron transport
G7071_02530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G7071_02535	COG0713	ATP synthesis coupled electron transport
G7071_02540	COG0839	Belongs to the complex I subunit 6 family
G7071_02545	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7071_02550	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G7071_02570	COG0649	NAD binding
G7071_02575	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7071_02580	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7071_02590	COG2226	methyltransferase
G7071_02600	COG1169	isochorismate synthase
G7071_02620	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G7071_02625	COG4948	Mandelate Racemase Muconate Lactonizing
G7071_02650	COG4552	Acetyltransferase involved in intracellular survival and related
G7071_02660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G7071_02665	COG1333	cytochrome c biogenesis protein
G7071_02670	COG0785	Cytochrome C biogenesis protein
G7071_02680	COG0406	alpha-ribazole phosphatase activity
G7071_02695	COG0113	porphobilinogen synthase activity
G7071_02700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G7071_02700	COG1648	precorrin-2 dehydrogenase activity
G7071_02710	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G7071_02715	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
G7071_02725	COG0318	PFAM AMP-dependent synthetase and ligase
G7071_02735	COG1595	DNA-templated transcription, initiation
G7071_02770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G7071_02775	COG0506	proline dehydrogenase activity
G7071_02785	COG0842	Transport permease protein
G7071_02785	COG1129	ABC transporter
G7071_02790	COG1309	transcriptional regulator
G7071_02795	COG1082	Xylose isomerase domain protein TIM barrel
G7071_02800	COG0248	Ppx GppA phosphatase
G7071_02825	COG1595	DNA-templated transcription, initiation
G7071_02830	COG1609	Transcriptional regulator
G7071_02835	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G7071_02840	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G7071_02870	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G7071_02880	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G7071_02885	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G7071_02890	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G7071_02925	COG1174	glycine betaine transport
G7071_02930	COG0517	IMP dehydrogenase activity
G7071_02930	COG1125	glycine betaine transport
G7071_02950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G7071_02955	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G7071_02965	COG0302	gtp cyclohydrolase
G7071_02985	COG0037	tRNA processing
G7071_02995	COG2027	D-alanyl-D-alanine carboxypeptidase
G7071_03000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G7071_03005	COG2226	methyltransferase
G7071_03030	COG3842	ATPase activity
G7071_03035	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G7071_03090	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G7071_03105	COG0596	Alpha beta hydrolase
G7071_03110	COG1366	Belongs to the anti-sigma-factor antagonist family
G7071_03130	COG1140	nitrate reductase beta subunit
G7071_03155	COG2197	response regulator
G7071_03190	COG5002	protein histidine kinase activity
G7071_03210	COG2197	response regulator
G7071_03215	COG4585	Histidine kinase
G7071_03240	COG2814	Major facilitator Superfamily
G7071_03245	COG1960	acyl-CoA dehydrogenase activity
G7071_03260	COG3850	Histidine kinase
G7071_03260	COG4999	Histidine kinase
G7071_03260	COG2205	protein histidine kinase activity
G7071_03260	COG3437	response regulator, receiver
G7071_03275	COG3850	Histidine kinase
G7071_03275	COG3437	response regulator, receiver
G7071_03275	COG2205	protein histidine kinase activity
G7071_03275	COG4999	Histidine kinase
G7071_03310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G7071_03315	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G7071_03370	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_03390	COG0579	oxidoreductase
G7071_03405	COG2890	protein-(glutamine-N5) methyltransferase activity
G7071_03415	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G7071_03420	COG1366	Belongs to the anti-sigma-factor antagonist family
G7071_03475	COG0589	response to stress
G7071_03490	COG3181	Tripartite tricarboxylate transporter family receptor
G7071_03495	COG3290	protein histidine kinase activity
G7071_03520	COG3275	phosphorelay sensor kinase activity
G7071_03525	COG3279	Response regulator of the LytR AlgR family
G7071_03535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G7071_03555	COG1278	Cold shock
G7071_03585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G7071_03590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7071_03605	COG0494	nUDIX hydrolase
G7071_03610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7071_03615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G7071_03625	COG1595	DNA-templated transcription, initiation
G7071_03660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7071_03695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7071_03740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G7071_03745	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G7071_03830	COG0433	COG0433 Predicted ATPase
G7071_03845	COG3263	regulation of cellular component size
G7071_03850	COG1053	succinate dehydrogenase
G7071_03855	COG0436	Aminotransferase
G7071_03885	COG0542	response to heat
G7071_03925	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G7071_03930	COG5001	Diguanylate cyclase
G7071_03930	COG5002	protein histidine kinase activity
G7071_03935	COG5002	protein histidine kinase activity
G7071_03935	COG5001	Diguanylate cyclase
G7071_03945	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G7071_04050	COG3447	MASE1 domain protein
G7071_04050	COG5001	Diguanylate cyclase
G7071_04050	COG5002	protein histidine kinase activity
G7071_04060	COG0346	lactoylglutathione lyase activity
G7071_04100	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G7071_04105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7071_04110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7071_04115	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G7071_04120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G7071_04135	COG3384	dioxygenase
G7071_04140	COG2267	carboxylic ester hydrolase activity
G7071_04145	COG1960	acyl-CoA dehydrogenase activity
G7071_04150	COG1960	acyl-CoA dehydrogenase activity
G7071_04155	COG0183	Belongs to the thiolase family
G7071_04165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G7071_04185	COG1960	acyl-CoA dehydrogenase activity
G7071_04195	COG2409	Drug exporters of the RND superfamily
G7071_04265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7071_04270	COG2205	protein histidine kinase activity
G7071_04295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7071_04335	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G7071_04360	COG1937	Protein conserved in bacteria
G7071_04375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G7071_04390	COG4948	Mandelate Racemase Muconate Lactonizing
G7071_04395	COG0589	response to stress
G7071_04415	COG0583	DNA-binding transcription factor activity
G7071_04450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G7071_04465	COG0189	ligase activity
G7071_04500	COG1960	acyl-CoA dehydrogenase activity
G7071_04515	COG0702	epimerase
G7071_04525	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G7071_04530	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G7071_04535	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G7071_04545	COG0590	tRNA wobble adenosine to inosine editing
G7071_04565	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G7071_04595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7071_04600	COG0746	molybdenum cofactor guanylyltransferase activity
G7071_04630	COG0561	phosphatase activity
G7071_04640	COG0561	phosphatase activity
G7071_04645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G7071_04650	COG1803	Methylglyoxal synthase
G7071_04650	COG1597	lipid kinase activity
G7071_04665	COG0077	Prephenate dehydratase
G7071_04665	COG1605	Chorismate mutase
G7071_04675	COG1691	(AIR) carboxylase
G7071_04700	COG2235	arginine
G7071_04710	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G7071_04730	COG0653	protein targeting
G7071_04745	COG2197	response regulator
G7071_04775	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G7071_04825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7071_04835	COG1309	transcriptional regulator
G7071_04845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G7071_04850	COG0386	Belongs to the glutathione peroxidase family
G7071_04855	COG0477	Major facilitator Superfamily
G7071_04865	COG0514	ATP-dependent DNA helicase (RecQ)
G7071_04875	COG2755	lipolytic protein G-D-S-L family
G7071_04890	COG3590	peptidase
G7071_04920	COG0477	Major facilitator Superfamily
G7071_04945	COG0437	4 iron, 4 sulfur cluster binding
G7071_04950	COG3383	formate dehydrogenase (NAD+) activity
G7071_04950	COG0243	molybdopterin cofactor binding
G7071_04960	COG0709	Synthesizes selenophosphate from selenide and ATP
G7071_04980	COG3239	Fatty acid desaturase
G7071_05000	COG2409	Drug exporters of the RND superfamily
G7071_05015	COG0386	Belongs to the glutathione peroxidase family
G7071_05035	COG1388	LysM domain
G7071_05035	COG3942	CHAP domain
G7071_05040	COG4763	Acyl-transferase
G7071_05050	COG1136	(ABC) transporter
G7071_05080	COG1716	ATPase activity
G7071_05095	COG0768	penicillin binding
G7071_05100	COG0515	serine threonine protein kinase
G7071_05105	COG0515	serine threonine protein kinase
G7071_05160	COG0517	IMP dehydrogenase activity
G7071_05190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G7071_05195	COG0187	DNA topoisomerase II activity
G7071_05200	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G7071_05205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G7071_05210	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G7071_05215	COG0592	DNA-directed DNA polymerase activity
G7071_05220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G7071_05225	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G7071_05230	COG0594	ribonuclease P activity
G7071_05235	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G7071_05240	COG0706	membrane insertase activity
G7071_05245	COG1847	R3H domain protein
G7071_05250	COG0357	Ribosomal RNA small subunit methyltransferase G
G7071_05255	COG1192	Involved in chromosome partitioning
G7071_05260	COG1475	DNA binding
G7071_05280	COG3118	belongs to the thioredoxin family
G7071_05295	COG1595	DNA-templated transcription, initiation
G7071_05305	COG0728	peptidoglycan biosynthetic process
G7071_05315	COG0617	tRNA 3'-terminal CCA addition
G7071_05330	COG1260	myo-inositol-1-phosphate synthase
G7071_05340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7071_05380	COG0360	Binds together with S18 to 16S ribosomal RNA
G7071_05385	COG0629	single-stranded DNA binding
G7071_05390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G7071_05395	COG0359	binds to the 23S rRNA
G7071_05405	COG0534	Mate efflux family protein
G7071_05410	COG0305	Participates in initiation and elongation during chromosome replication
G7071_05435	COG1595	DNA-templated transcription, initiation
G7071_05445	COG0667	Aldo Keto reductase
G7071_05485	COG0667	Aldo Keto reductase
G7071_05535	COG0189	ligase activity
G7071_05535	COG4067	protein conserved in archaea
G7071_05540	COG0569	domain protein
G7071_05540	COG0189	ligase activity
G7071_05610	COG2197	response regulator
G7071_05645	COG0277	FAD linked oxidase domain protein
G7071_05650	COG1597	lipid kinase activity
G7071_05700	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7071_05700	COG0596	Alpha beta hydrolase
G7071_05715	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7071_05715	COG1902	pentaerythritol trinitrate reductase activity
G7071_05730	COG0626	cystathionine gamma-synthase activity
G7071_05735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7071_05750	COG0513	Belongs to the DEAD box helicase family
G7071_05770	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G7071_05780	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_05785	COG0318	PFAM AMP-dependent synthetase and ligase
G7071_05790	COG0183	Belongs to the thiolase family
G7071_05795	COG1024	Enoyl-CoA hydratase
G7071_05800	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7071_05805	COG1960	acyl-CoA dehydrogenase activity
G7071_05810	COG1960	acyl-CoA dehydrogenase activity
G7071_05825	COG0183	Belongs to the thiolase family
G7071_05835	COG0842	Transport permease protein
G7071_05835	COG1129	ABC transporter
G7071_05845	COG5473	translation initiation factor activity
G7071_05850	COG1714	RDD family
G7071_05855	COG1695	Transcriptional regulator
G7071_05860	COG1136	(ABC) transporter
G7071_05860	COG0577	efflux transmembrane transporter activity
G7071_05885	COG1960	acyl-CoA dehydrogenase activity
G7071_05895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7071_05915	COG1733	regulation of RNA biosynthetic process
G7071_05955	COG1595	DNA-templated transcription, initiation
G7071_05960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G7071_05980	COG1595	DNA-templated transcription, initiation
G7071_05995	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G7071_06010	COG3119	arylsulfatase activity
G7071_06020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G7071_06020	COG0512	Glutamine amidotransferase of anthranilate synthase
G7071_06030	COG0745	RESPONSE REGULATOR receiver
G7071_06055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G7071_06065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G7071_06070	COG0435	Glutathione S-transferase
G7071_06090	COG0022	dehydrogenase e1 component
G7071_06095	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7071_06100	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G7071_06105	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_06120	COG1595	DNA-templated transcription, initiation
G7071_06200	COG4221	oxidoreductase activity
G7071_06210	COG2197	response regulator
G7071_06215	COG4585	Histidine kinase
G7071_06225	COG1131	(ABC) transporter
G7071_06230	COG1960	acyl-CoA dehydrogenase activity
G7071_06235	COG0730	response to heat
G7071_06280	COG2755	lipolytic protein G-D-S-L family
G7071_06285	COG0717	Belongs to the dCTP deaminase family
G7071_06295	COG0247	lactate metabolic process
G7071_06295	COG2181	nitrate reductase activity
G7071_06315	COG2986	histidine ammonia-lyase
G7071_06340	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G7071_06370	COG2301	Belongs to the HpcH HpaI aldolase family
G7071_06375	COG2301	Belongs to the HpcH HpaI aldolase family
G7071_06400	COG0778	Nitroreductase
G7071_06425	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G7071_06425	COG1672	PFAM Archaeal ATPase
G7071_06430	COG2197	response regulator
G7071_06465	COG0748	coenzyme F420 binding
G7071_06500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G7071_06510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G7071_06515	COG0484	heat shock protein binding
G7071_06530	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G7071_06550	COG1459	type II secretion system
G7071_06575	COG0542	response to heat
G7071_06585	COG0277	FAD linked oxidase domain protein
G7071_06605	COG0702	epimerase
G7071_06625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G7071_06630	COG0586	Pfam SNARE associated Golgi protein
G7071_06675	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
G7071_06695	COG1597	lipid kinase activity
G7071_06700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G7071_06710	COG0151	Belongs to the GarS family
G7071_06715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G7071_06725	COG0477	Major facilitator Superfamily
G7071_06735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G7071_06745	COG0318	PFAM AMP-dependent synthetase and ligase
G7071_06760	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G7071_06765	COG0047	phosphoribosylformylglycinamidine synthase activity
G7071_06770	COG2409	Drug exporters of the RND superfamily
G7071_06780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G7071_06805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7071_06815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G7071_06825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G7071_06855	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G7071_06860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G7071_06900	COG1278	Cold shock
G7071_06920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G7071_06925	COG0573	inorganic phosphate transmembrane transporter activity
G7071_06935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G7071_06945	COG0306	phosphate transporter
G7071_06955	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G7071_06965	COG4044	May play a role in the intracellular transport of hydrophobic ligands
G7071_06975	COG0354	folic acid binding
G7071_06980	COG0456	acetyltransferase
G7071_06980	COG0454	-acetyltransferase
G7071_06985	COG0745	RESPONSE REGULATOR receiver
G7071_07035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G7071_07120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G7071_07125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G7071_07130	COG0297	glycogen (starch) synthase activity
G7071_07135	COG1181	Belongs to the D-alanine--D-alanine ligase family
G7071_07145	COG1086	Polysaccharide biosynthesis protein
G7071_07150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G7071_07155	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G7071_07160	COG0438	transferase activity, transferring glycosyl groups
G7071_07165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7071_07230	COG0489	protein tyrosine kinase activity
G7071_07240	COG1086	Polysaccharide biosynthesis protein
G7071_07260	COG0730	response to heat
G7071_07265	COG0529	Catalyzes the synthesis of activated sulfate
G7071_07300	COG0662	Cupin 2, conserved barrel domain protein
G7071_07300	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G7071_07310	COG1088	dTDP-glucose 4,6-dehydratase activity
G7071_07345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7071_07375	COG0693	protein deglycase activity
G7071_07410	COG1794	racemase activity, acting on amino acids and derivatives
G7071_07420	COG0328	RNA-DNA hybrid ribonuclease activity
G7071_07425	COG0438	transferase activity, transferring glycosyl groups
G7071_07435	COG0697	spore germination
G7071_07445	COG5002	protein histidine kinase activity
G7071_07455	COG0588	phosphoglycerate mutase activity
G7071_07470	COG1329	Transcriptional regulator
G7071_07480	COG0668	transmembrane transport
G7071_07490	COG2223	nitrite transmembrane transporter activity
G7071_07495	COG0243	molybdopterin cofactor binding
G7071_07500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G7071_07545	COG2146	nitrite reductase [NAD(P)H] activity
G7071_07545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G7071_07560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G7071_07580	COG0215	cysteine-tRNA ligase activity
G7071_07645	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G7071_07650	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G7071_07655	COG1012	belongs to the aldehyde dehydrogenase family
G7071_07660	COG3384	dioxygenase
G7071_07665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G7071_07700	COG0069	glutamate synthase activity
G7071_07705	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G7071_07755	COG1595	DNA-templated transcription, initiation
G7071_07765	COG0459	protein refolding
G7071_07785	COG0489	protein tyrosine kinase activity
G7071_07785	COG3206	protein involved in exopolysaccharide biosynthesis
G7071_07790	COG1136	(ABC) transporter
G7071_07790	COG4591	ABC-type transport system involved in lipoprotein release permease component
G7071_07800	COG2188	Transcriptional regulator
G7071_07810	COG1061	Type III restriction enzyme res subunit
G7071_07855	COG1278	Cold shock
G7071_07860	COG2814	Major facilitator Superfamily
G7071_07880	COG2252	PERMEase
G7071_07885	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G7071_07890	COG0049	tRNA binding
G7071_07895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G7071_07905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G7071_07930	COG0714	Associated with various cellular activities
G7071_07950	COG0051	transcription antitermination factor activity, RNA binding
G7071_07955	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G7071_07960	COG0088	Forms part of the polypeptide exit tunnel
G7071_07965	COG0089	rRNA binding
G7071_07970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G7071_07975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G7071_07980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G7071_07985	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G7071_07990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G7071_08000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G7071_08005	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G7071_08010	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G7071_08015	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G7071_08020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G7071_08025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G7071_08030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G7071_08035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G7071_08040	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G7071_08045	COG1841	ribosomal large subunit assembly
G7071_08050	COG0200	Binds to the 23S rRNA
G7071_08060	COG0563	adenylate kinase activity
G7071_08100	COG0714	Associated with various cellular activities
G7071_08120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G7071_08125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G7071_08130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G7071_08135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G7071_08145	COG0202	RNA polymerase activity
G7071_08150	COG0203	ribosomal protein L17
G7071_08155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7071_08180	COG0101	tRNA pseudouridine synthase activity
G7071_08185	COG2813	Specifically methylates the guanine in position
G7071_08225	COG0411	ABC transporter
G7071_08230	COG3835	regulator
G7071_08240	COG1960	acyl-CoA dehydrogenase activity
G7071_08245	COG1960	acyl-CoA dehydrogenase activity
G7071_08250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7071_08265	COG4585	Histidine kinase
G7071_08270	COG2197	response regulator
G7071_08275	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G7071_08280	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G7071_08285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7071_08295	COG1072	(Pantothenic acid kinase))
G7071_08300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G7071_08305	COG0736	holo-[acyl-carrier-protein] synthase activity
G7071_08315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G7071_08325	COG0802	atpase or kinase
G7071_08330	COG1214	PFAM Peptidase M22, glycoprotease
G7071_08330	COG0456	acetyltransferase
G7071_08355	COG1472	Belongs to the glycosyl hydrolase 3 family
G7071_08375	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G7071_08380	COG0459	protein refolding
G7071_08395	COG0463	Glycosyl transferase, family 2
G7071_08400	COG1088	dTDP-glucose 4,6-dehydratase activity
G7071_08405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G7071_08430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7071_08440	COG0516	GMP reductase activity
G7071_08450	COG1012	belongs to the aldehyde dehydrogenase family
G7071_08460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7071_08460	COG0519	Catalyzes the synthesis of GMP from XMP
G7071_08480	COG2409	Drug exporters of the RND superfamily
G7071_08545	COG3227	Zinc metalloprotease (Elastase)
G7071_08595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7071_08600	COG1132	(ABC) transporter
G7071_08605	COG1132	(ABC) transporter
G7071_08630	COG4585	Histidine kinase
G7071_08635	COG2197	response regulator
G7071_08640	COG0531	amino acid
G7071_08665	COG0741	lytic transglycosylase activity
G7071_08665	COG1196	nuclear chromosome segregation
G7071_08665	COG0739	heme binding
G7071_08670	COG0415	Belongs to the DNA photolyase family
G7071_08675	COG0045	succinate-CoA ligase (ADP-forming) activity
G7071_08700	COG0138	bifunctional purine biosynthesis protein purh
G7071_08710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G7071_08720	COG0039	L-malate dehydrogenase activity
G7071_08735	COG2838	Isocitrate dehydrogenase
G7071_08740	COG2814	Major facilitator Superfamily
G7071_08760	COG1295	ribonuclease BN
G7071_08765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G7071_08815	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G7071_08815	COG1473	amidohydrolase
G7071_08860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G7071_08885	COG1012	belongs to the aldehyde dehydrogenase family
G7071_08890	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G7071_08900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7071_08930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G7071_08940	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_08965	COG0823	Involved in the tonB-independent uptake of proteins
G7071_08990	COG2329	Antibiotic biosynthesis monooxygenase
G7071_08995	COG2247	cell wall binding repeat
G7071_08995	COG2385	sporulation resulting in formation of a cellular spore
G7071_09010	COG4770	biotin carboxylase activity
G7071_09020	COG3842	ATPase activity
G7071_09035	COG1960	acyl-CoA dehydrogenase activity
G7071_09050	COG1960	acyl-CoA dehydrogenase activity
G7071_09060	COG0424	maF-like protein
G7071_09080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7071_09090	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G7071_09095	COG0745	RESPONSE REGULATOR receiver
G7071_09105	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G7071_09110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G7071_09115	COG1832	CoA-binding protein
G7071_09130	COG1960	acyl-CoA dehydrogenase activity
G7071_09150	COG1024	Enoyl-CoA hydratase
G7071_09155	COG1316	TRANSCRIPTIONal
G7071_09160	COG1607	acyl-coa hydrolase
G7071_09170	COG1216	Glycosyl transferase, family 2
G7071_09185	COG1216	Glycosyl transferase, family 2
G7071_09215	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G7071_09215	COG0662	Cupin 2, conserved barrel domain protein
G7071_09225	COG0778	Nitroreductase
G7071_09225	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G7071_09230	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G7071_09275	COG2835	tetraacyldisaccharide 4'-kinase activity
G7071_09285	COG2354	Protein conserved in bacteria
G7071_09290	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G7071_09295	COG0745	RESPONSE REGULATOR receiver
G7071_09300	COG5000	phosphorelay sensor kinase activity
G7071_09300	COG5002	protein histidine kinase activity
G7071_09305	COG0823	Involved in the tonB-independent uptake of proteins
G7071_09315	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G7071_09330	COG0653	protein targeting
G7071_09355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G7071_09370	COG2239	Acts as a magnesium transporter
G7071_09420	COG1960	acyl-CoA dehydrogenase activity
G7071_09440	COG2030	dehydratase
G7071_09460	COG0300	oxidoreductase activity
G7071_09465	COG1192	Involved in chromosome partitioning
G7071_09480	COG0513	Belongs to the DEAD box helicase family
G7071_09490	COG2261	transglycosylase associated protein
G7071_09500	COG1309	transcriptional regulator
G7071_09525	COG0813	purine-nucleoside phosphorylase activity
G7071_09530	COG2816	NAD+ diphosphatase activity
G7071_09580	COG1796	DNA polymerase
G7071_09580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G7071_09590	COG3835	regulator
G7071_09620	COG3480	Lon protease (S16) C-terminal proteolytic domain
G7071_09630	COG1615	UPF0182 protein
G7071_09705	COG0210	DNA helicase
G7071_09745	COG0739	heme binding
G7071_09830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G7071_09840	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G7071_09850	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G7071_09860	COG1196	nuclear chromosome segregation
G7071_09925	COG2814	Major facilitator Superfamily
G7071_09930	COG0640	Transcriptional regulator
G7071_09935	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G7071_09950	COG0640	Transcriptional regulator
G7071_09965	COG4974	Belongs to the 'phage' integrase family
G7071_10000	COG2409	Drug exporters of the RND superfamily
G7071_10020	COG1309	transcriptional regulator
G7071_10085	COG0778	Nitroreductase
G7071_10105	COG1797	cobyrinic acid a,c-diamide synthase activity
G7071_10110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G7071_10115	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G7071_10150	COG1492	cobalamin metabolic process
G7071_10165	COG0406	alpha-ribazole phosphatase activity
G7071_10215	COG2132	Multicopper oxidase
G7071_10230	COG2205	protein histidine kinase activity
G7071_10240	COG1937	Protein conserved in bacteria
G7071_10255	COG2217	Heavy metal translocating P-type atpase
G7071_10300	COG0739	heme binding
G7071_10300	COG1196	nuclear chromosome segregation
G7071_10300	COG0741	lytic transglycosylase activity
G7071_10355	COG2801	Transposase and inactivated derivatives
G7071_10355	COG3415	Transposase
G7071_10365	COG1064	alcohol dehydrogenase
G7071_10430	COG0175	sulfate reduction
G7071_10450	COG0745	RESPONSE REGULATOR receiver
G7071_10470	COG0745	RESPONSE REGULATOR receiver
G7071_10540	COG0583	DNA-binding transcription factor activity
G7071_10545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G7071_10550	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G7071_10560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7071_10620	COG1176	ABC-type spermidine putrescine transport system, permease component I
G7071_10625	COG1177	transmembrane transport
G7071_10630	COG1228	amidohydrolase
G7071_10635	COG1012	belongs to the aldehyde dehydrogenase family
G7071_10645	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7071_10645	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7071_10645	COG1703	isobutyryl-CoA mutase activity
G7071_10650	COG1846	Transcriptional regulator
G7071_10670	COG4221	oxidoreductase activity
G7071_10675	COG2124	cytochrome p450
G7071_10690	COG1012	belongs to the aldehyde dehydrogenase family
G7071_10750	COG2030	dehydratase
G7071_10750	COG1012	belongs to the aldehyde dehydrogenase family
G7071_10755	COG3396	Phenylacetate-CoA oxygenase
G7071_10760	COG3460	Phenylacetate-CoA oxygenase
G7071_10765	COG3396	Phenylacetate-CoA oxygenase
G7071_10770	COG2151	metal-sulfur cluster biosynthetic enzyme
G7071_10785	COG1309	transcriptional regulator
G7071_10790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G7071_10815	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_10820	COG1960	acyl-CoA dehydrogenase activity
G7071_10840	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G7071_10845	COG2733	membrane
G7071_10850	COG2501	S4 domain
G7071_10865	COG0483	inositol monophosphate 1-phosphatase activity
G7071_10880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G7071_10890	COG2135	peptidase activity
G7071_10900	COG1595	DNA-templated transcription, initiation
G7071_10905	COG5662	AntiSigma factor
G7071_10915	COG1191	sigma factor activity
G7071_10960	COG2172	sigma factor antagonist activity
G7071_10980	COG0215	cysteine-tRNA ligase activity
G7071_11000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G7071_11005	COG0604	alcohol dehydrogenase
G7071_11010	COG4221	oxidoreductase activity
G7071_11035	COG0567	Dehydrogenase, E1 component
G7071_11035	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7071_11045	COG1316	TRANSCRIPTIONal
G7071_11055	COG0018	arginyl-trna synthetase
G7071_11060	COG0019	diaminopimelate decarboxylase activity
G7071_11065	COG0460	homoserine dehydrogenase
G7071_11070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G7071_11075	COG0083	homoserine kinase activity
G7071_11085	COG0254	rRNA binding
G7071_11090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G7071_11095	COG2890	protein-(glutamine-N5) methyltransferase activity
G7071_11105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G7071_11120	COG0356	it plays a direct role in the translocation of protons across the membrane
G7071_11125	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G7071_11130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G7071_11135	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G7071_11140	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G7071_11145	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G7071_11150	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G7071_11155	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G7071_11190	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G7071_11195	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7071_11200	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7071_11210	COG2378	regulation of single-species biofilm formation
G7071_11220	COG0596	Alpha beta hydrolase
G7071_11250	COG0346	lactoylglutathione lyase activity
G7071_11255	COG0183	Belongs to the thiolase family
G7071_11290	COG2409	Drug exporters of the RND superfamily
G7071_11320	COG1937	Protein conserved in bacteria
G7071_11335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7071_11335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G7071_11340	COG0730	response to heat
G7071_11345	COG2409	Drug exporters of the RND superfamily
G7071_11365	COG0697	spore germination
G7071_11380	COG0438	transferase activity, transferring glycosyl groups
G7071_11400	COG2132	Multicopper oxidase
G7071_11405	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G7071_11410	COG3281	Trehalose synthase
G7071_11430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G7071_11470	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G7071_11480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G7071_11490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G7071_11495	COG0799	negative regulation of ribosome biogenesis
G7071_11525	COG0640	Transcriptional regulator
G7071_11540	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_11550	COG0495	leucyl-tRNA aminoacylation
G7071_11565	COG1307	EDD domain protein, DegV family
G7071_11570	COG1555	photosystem II stabilization
G7071_11585	COG0268	Binds directly to 16S ribosomal RNA
G7071_11605	COG0481	GTPase activity
G7071_11645	COG1420	regulation of RNA biosynthetic process
G7071_11665	COG0537	adenosine 5'-monophosphoramidase activity
G7071_11670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G7071_11685	COG1022	Amp-dependent synthetase and ligase
G7071_11725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G7071_11745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G7071_11755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G7071_11760	COG0456	acetyltransferase
G7071_11795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7071_11800	COG0596	Alpha beta hydrolase
G7071_11805	COG1381	Involved in DNA repair and RecF pathway recombination
G7071_11810	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G7071_11820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G7071_11825	COG1121	(ABC) transporter
G7071_11830	COG3443	Belongs to the bacterial solute-binding protein 9 family
G7071_11830	COG0803	Belongs to the bacterial solute-binding protein 9 family
G7071_11840	COG0423	glycine-tRNA ligase activity
G7071_11860	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G7071_11895	COG2755	lipolytic protein G-D-S-L family
G7071_11900	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G7071_11905	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G7071_11920	COG0582	viral genome integration into host DNA
G7071_11990	COG0515	serine threonine protein kinase
G7071_11990	COG2815	serine threonine protein kinase
G7071_12020	COG0596	Alpha beta hydrolase
G7071_12040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7071_12045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7071_12050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G7071_12080	COG0318	PFAM AMP-dependent synthetase and ligase
G7071_12105	COG0745	RESPONSE REGULATOR receiver
G7071_12135	COG3022	response to hydroperoxide
G7071_12140	COG0557	exoribonuclease II activity
G7071_12190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G7071_12190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7071_12200	COG0174	glutamine synthetase
G7071_12205	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G7071_12225	COG0776	regulation of translation
G7071_12255	COG2072	flavoprotein involved in K transport
G7071_12280	COG0366	Alpha amylase catalytic
G7071_12280	COG1470	cell adhesion involved in biofilm formation
G7071_12345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7071_12345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7071_12355	COG3485	protocatechuate 3,4-dioxygenase
G7071_12360	COG4948	Mandelate Racemase Muconate Lactonizing
G7071_12365	COG0583	DNA-binding transcription factor activity
G7071_12370	COG0477	Major facilitator Superfamily
G7071_12390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G7071_12400	COG0583	DNA-binding transcription factor activity
G7071_12435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G7071_12435	COG2755	lipolytic protein G-D-S-L family
G7071_12440	COG3559	Exporter of polyketide antibiotics
G7071_12445	COG1131	(ABC) transporter
G7071_12450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7071_12455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7071_12465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G7071_12470	COG2267	carboxylic ester hydrolase activity
G7071_12475	COG1053	succinate dehydrogenase
G7071_12495	COG1053	succinate dehydrogenase
G7071_12500	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_12525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7071_12590	COG2318	DinB family
G7071_12605	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_12610	COG0183	Belongs to the thiolase family
G7071_12620	COG2030	dehydratase
G7071_12635	COG0318	PFAM AMP-dependent synthetase and ligase
G7071_12640	COG0318	PFAM AMP-dependent synthetase and ligase
G7071_12675	COG1960	acyl-CoA dehydrogenase activity
G7071_12685	COG1309	transcriptional regulator
G7071_12690	COG0318	PFAM AMP-dependent synthetase and ligase
G7071_12695	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_12705	COG0747	negative chemotaxis
G7071_12710	COG0601	transmembrane transport
G7071_12725	COG4608	Belongs to the ABC transporter superfamily
G7071_12760	COG0300	oxidoreductase activity
G7071_12765	COG0747	negative chemotaxis
G7071_12775	COG1960	acyl-CoA dehydrogenase activity
G7071_12785	COG1960	acyl-CoA dehydrogenase activity
G7071_12795	COG0183	Belongs to the thiolase family
G7071_12815	COG0655	NAD(P)H dehydrogenase (quinone) activity
G7071_12845	COG1122	ATPase activity
G7071_12850	COG0183	Belongs to the thiolase family
G7071_12860	COG1268	BioY protein
G7071_12915	COG0410	ABC transporter
G7071_12935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7071_12945	COG1024	Enoyl-CoA hydratase
G7071_12970	COG0183	Belongs to the thiolase family
G7071_13000	COG2186	Transcriptional regulator
G7071_13010	COG1012	belongs to the aldehyde dehydrogenase family
G7071_13015	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_13020	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G7071_13025	COG0174	glutamine synthetase
G7071_13050	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G7071_13060	COG1131	(ABC) transporter
G7071_13065	COG0321	lipoyl(octanoyl) transferase activity
G7071_13075	COG1090	epimerase
G7071_13085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7071_13095	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G7071_13110	COG0384	phenazine biosynthesis protein PhzF
G7071_13115	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G7071_13140	COG0494	nUDIX hydrolase
G7071_13150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G7071_13155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G7071_13165	COG1674	ftsk spoiiie
G7071_13175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G7071_13190	COG3387	PFAM Glycoside hydrolase 15-related
G7071_13195	COG1546	Belongs to the CinA family
G7071_13195	COG1058	Belongs to the CinA family
G7071_13200	COG1396	sequence-specific DNA binding
G7071_13205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G7071_13210	COG1201	RNA secondary structure unwinding
G7071_13215	COG0783	Belongs to the Dps family
G7071_13220	COG0251	oxidation-reduction process
G7071_13245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7071_13255	COG2814	Major facilitator Superfamily
G7071_13260	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G7071_13275	COG2326	polyphosphate kinase activity
G7071_13295	COG0175	sulfate reduction
G7071_13305	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G7071_13310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G7071_13315	COG5002	protein histidine kinase activity
G7071_13320	COG0275	rRNA processing
G7071_13325	COG1960	acyl-CoA dehydrogenase activity
G7071_13350	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G7071_13380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G7071_13400	COG0134	indole-3-glycerol-phosphate synthase activity
G7071_13405	COG0133	tryptophan synthase activity
G7071_13410	COG0159	tryptophan synthase activity
G7071_13415	COG1999	signal sequence binding
G7071_13420	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G7071_13425	COG0070	glutamate synthase
G7071_13425	COG0069	glutamate synthase activity
G7071_13425	COG0067	glutamate synthase
G7071_13435	COG0469	pyruvate kinase activity
G7071_13455	COG0683	leucine binding
G7071_13480	COG1126	abc transporter atp-binding protein
G7071_13485	COG0765	amino acid transport
G7071_13490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7071_13525	COG0438	transferase activity, transferring glycosyl groups
G7071_13535	COG4981	capsule polysaccharide biosynthetic process
G7071_13555	COG2226	methyltransferase
G7071_13560	COG0539	negative regulation of cytoplasmic translation
G7071_13570	COG0318	PFAM AMP-dependent synthetase and ligase
G7071_13580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7071_13595	COG0237	dephospho-CoA kinase activity
G7071_13615	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G7071_13625	COG1984	allophanate hydrolase subunit 2
G7071_13630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G7071_13650	COG0589	response to stress
G7071_13695	COG0187	DNA topoisomerase II activity
G7071_13720	COG0477	Major facilitator Superfamily
G7071_13730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G7071_13760	COG1435	thymidine kinase activity
G7071_13770	COG4221	oxidoreductase activity
G7071_13780	COG2860	membrane
G7071_13815	COG0756	dUTP diphosphatase activity
G7071_13840	COG0569	domain protein
G7071_13845	COG0531	amino acid
G7071_13850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7071_13915	COG1051	belongs to the nudix hydrolase family
G7071_13920	COG3386	PFAM SMP-30 Gluconolaconase
G7071_13925	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G7071_13940	COG0733	neurotransmitter:sodium symporter activity
G7071_13955	COG1024	Enoyl-CoA hydratase
G7071_13955	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7071_13960	COG0183	Belongs to the thiolase family
G7071_13970	COG1946	Acyl-CoA thioesterase
G7071_13985	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_13990	COG0183	Belongs to the thiolase family
G7071_13995	COG2815	serine threonine protein kinase
G7071_13995	COG0515	serine threonine protein kinase
G7071_14000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G7071_14005	COG0540	Belongs to the ATCase OTCase family
G7071_14010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G7071_14020	COG0427	acetyl-CoA hydrolase
G7071_14030	COG0505	Belongs to the CarA family
G7071_14035	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G7071_14040	COG0167	dihydroorotate dehydrogenase activity
G7071_14050	COG0167	dihydroorotate dehydrogenase activity
G7071_14055	COG0284	orotidine-5'-phosphate decarboxylase activity
G7071_14070	COG0194	GDP metabolic process
G7071_14075	COG1758	RNA polymerase activity
G7071_14085	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G7071_14090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G7071_14100	COG0242	peptide deformylase activity
G7071_14105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G7071_14135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G7071_14155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G7071_14155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G7071_14160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G7071_14165	COG0140	phosphoribosyl-ATP diphosphatase activity
G7071_14170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G7071_14205	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G7071_14210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G7071_14215	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G7071_14220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G7071_14225	COG5002	protein histidine kinase activity
G7071_14235	COG5002	protein histidine kinase activity
G7071_14240	COG0745	RESPONSE REGULATOR receiver
G7071_14245	COG2205	protein histidine kinase activity
G7071_14250	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G7071_14265	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G7071_14275	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G7071_14280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G7071_14285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G7071_14290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G7071_14295	COG1438	arginine binding
G7071_14300	COG0137	argininosuccinate synthase activity
G7071_14305	COG0165	Argininosuccinate lyase
G7071_14310	COG2094	Belongs to the DNA glycosylase MPG family
G7071_14340	COG0647	UMP catabolic process
G7071_14355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G7071_14360	COG0497	DNA recombination
G7071_14375	COG0504	CTP synthase activity
G7071_14385	COG0494	nUDIX hydrolase
G7071_14390	COG0686	Belongs to the AlaDH PNT family
G7071_14420	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G7071_14430	COG4401	Chorismate mutase type I
G7071_14440	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G7071_14445	COG0204	Acyl-transferase
G7071_14455	COG1160	GTP binding
G7071_14460	COG0739	heme binding
G7071_14460	COG1196	nuclear chromosome segregation
G7071_14460	COG0741	lytic transglycosylase activity
G7071_14470	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G7071_14475	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G7071_14485	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G7071_14495	COG1492	cobalamin metabolic process
G7071_14505	COG1120	ATPase activity
G7071_14510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7071_14515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G7071_14525	COG0406	alpha-ribazole phosphatase activity
G7071_14545	COG3119	arylsulfatase activity
G7071_14550	COG1253	flavin adenine dinucleotide binding
G7071_14580	COG0509	glycine decarboxylation via glycine cleavage system
G7071_14585	COG1716	ATPase activity
G7071_14620	COG0419	ATPase involved in DNA repair
G7071_14625	COG0420	3'-5' exonuclease activity
G7071_14630	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G7071_14650	COG0584	glycerophosphoryl diester phosphodiesterase
G7071_14655	COG0549	Belongs to the carbamate kinase family
G7071_14665	COG1309	transcriptional regulator
G7071_14675	COG2814	Major facilitator Superfamily
G7071_14685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G7071_14700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G7071_14705	COG0798	PFAM Bile acid sodium symporter
G7071_14710	COG0640	Transcriptional regulator
G7071_14760	COG1216	Glycosyl transferase, family 2
G7071_14770	COG1607	acyl-coa hydrolase
G7071_14780	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G7071_14785	COG0604	alcohol dehydrogenase
G7071_14805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G7071_14835	COG0805	protein transport
G7071_14840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G7071_14845	COG2378	regulation of single-species biofilm formation
G7071_14860	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G7071_14865	COG0723	plastoquinol--plastocyanin reductase activity
G7071_14875	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G7071_14885	COG2827	Endonuclease containing a URI domain
G7071_14890	COG4122	O-methyltransferase activity
G7071_14895	COG2226	methyltransferase
G7071_14900	COG1222	aaa ATPase
G7071_14905	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G7071_14915	COG1994	Peptidase M50
G7071_14915	COG0517	IMP dehydrogenase activity
G7071_14925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7071_14965	COG0215	cysteine-tRNA ligase activity
G7071_14985	COG0598	Magnesium transport protein CorA
G7071_14995	COG1968	undecaprenyl-diphosphatase activity
G7071_15000	COG0667	Aldo Keto reductase
G7071_15025	COG0438	transferase activity, transferring glycosyl groups
G7071_15065	COG2205	protein histidine kinase activity
G7071_15070	COG0741	lytic transglycosylase activity
G7071_15080	COG1278	Cold shock
G7071_15085	COG0596	Alpha beta hydrolase
G7071_15110	COG0464	growth
G7071_15120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7071_15145	COG1716	ATPase activity
G7071_15170	COG0076	glutamate decarboxylase activity
G7071_15185	COG1960	acyl-CoA dehydrogenase activity
G7071_15195	COG0242	peptide deformylase activity
G7071_15210	COG1881	PFAM PEBP family protein
G7071_15260	COG1119	ATPase activity
G7071_15270	COG0560	Phosphoserine phosphatase
G7071_15270	COG3830	Belongs to the UPF0237 family
G7071_15290	COG3360	Dodecin
G7071_15305	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G7071_15370	COG1132	(ABC) transporter
G7071_15375	COG1024	Enoyl-CoA hydratase
G7071_15385	COG0488	(ABC) transporter
G7071_15415	COG2151	metal-sulfur cluster biosynthetic enzyme
G7071_15420	COG0822	iron-sulfur transferase activity
G7071_15425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G7071_15430	COG0396	ATPase activity
G7071_15440	COG0719	Fe-S assembly protein
G7071_15445	COG0719	Fe-S assembly protein
G7071_15485	COG1131	(ABC) transporter
G7071_15500	COG0109	protoheme IX farnesyltransferase activity
G7071_15510	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G7071_15530	COG0363	glucosamine-6-phosphate deaminase activity
G7071_15545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G7071_15550	COG0149	triose-phosphate isomerase activity
G7071_15555	COG0126	phosphoglycerate kinase activity
G7071_15560	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G7071_15565	COG1481	regulation of sporulation
G7071_15575	COG1660	Displays ATPase and GTPase activities
G7071_15580	COG0322	excinuclease ABC activity
G7071_15590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G7071_15605	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G7071_15625	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G7071_15700	COG1960	acyl-CoA dehydrogenase activity
G7071_15705	COG1960	acyl-CoA dehydrogenase activity
G7071_15715	COG2070	2-Nitropropane dioxygenase
G7071_15725	COG1024	Enoyl-CoA hydratase
G7071_15730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7071_15740	COG0318	PFAM AMP-dependent synthetase and ligase
G7071_15745	COG2267	carboxylic ester hydrolase activity
G7071_15750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7071_15770	COG2124	cytochrome p450
G7071_15775	COG0183	Belongs to the thiolase family
G7071_15780	COG1960	acyl-CoA dehydrogenase activity
G7071_15785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7071_15795	COG0488	(ABC) transporter
G7071_15820	COG0339	signal peptide processing
G7071_15825	COG0702	epimerase
G7071_15835	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_15840	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_15845	COG1024	Enoyl-CoA hydratase
G7071_15875	COG3119	arylsulfatase activity
G7071_15885	COG0183	Belongs to the thiolase family
G7071_15890	COG1309	transcriptional regulator
G7071_15900	COG1960	acyl-CoA dehydrogenase activity
G7071_15905	COG0318	PFAM AMP-dependent synthetase and ligase
G7071_15910	COG1960	acyl-CoA dehydrogenase activity
G7071_15915	COG1960	acyl-CoA dehydrogenase activity
G7071_15920	COG1960	acyl-CoA dehydrogenase activity
G7071_15935	COG0346	lactoylglutathione lyase activity
G7071_15940	COG2267	carboxylic ester hydrolase activity
G7071_15945	COG1960	acyl-CoA dehydrogenase activity
G7071_15955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7071_15965	COG3971	2-oxopent-4-enoate hydratase activity
G7071_15970	COG1053	succinate dehydrogenase
G7071_15975	COG2030	dehydratase
G7071_16000	COG1960	acyl-CoA dehydrogenase activity
G7071_16020	COG1960	acyl-CoA dehydrogenase activity
G7071_16035	COG2226	methyltransferase
G7071_16040	COG0438	transferase activity, transferring glycosyl groups
G7071_16045	COG1309	transcriptional regulator
G7071_16055	COG1028	Short-chain dehydrogenase reductase Sdr
G7071_16065	COG0492	ferredoxin-NADP+ reductase activity
G7071_16120	COG5592	hemerythrin HHE cation binding domain
G7071_16125	COG0556	nucleotide-excision repair
G7071_16130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7071_16140	COG3483	tryptophan 2,3-dioxygenase activity
G7071_16155	COG1793	dna ligase
G7071_16165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7071_16175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7071_16180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G7071_16200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G7071_16205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G7071_16210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G7071_16215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G7071_16225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G7071_16235	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G7071_16240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G7071_16255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7071_16265	COG4608	Belongs to the ABC transporter superfamily
G7071_16270	COG0444	Belongs to the ABC transporter superfamily
G7071_16275	COG0601	transmembrane transport
G7071_16285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7071_16305	COG0124	histidyl-tRNA synthetase
G7071_16315	COG1196	nuclear chromosome segregation
G7071_16320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7071_16325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G7071_16330	COG1862	Preprotein translocase
G7071_16335	COG2255	four-way junction helicase activity
G7071_16340	COG0632	four-way junction helicase activity
G7071_16345	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G7071_16350	COG0217	transcriptional regulatory protein
G7071_16355	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G7071_16390	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
G7071_16400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G7071_16405	COG0483	inositol monophosphate 1-phosphatase activity
G7071_16425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G7071_16435	COG1132	(ABC) transporter
G7071_16440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G7071_16465	COG1012	belongs to the aldehyde dehydrogenase family
G7071_16480	COG0589	response to stress
G7071_16495	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G7071_16500	COG0674	pyruvate-flavodoxin oxidoreductase activity
G7071_16505	COG1013	pyruvate-flavodoxin oxidoreductase activity
G7071_16510	COG0493	'glutamate synthase
G7071_16510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G7071_16515	COG1181	Belongs to the D-alanine--D-alanine ligase family
G7071_16515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G7071_16520	COG3848	Pyruvate phosphate dikinase
G7071_16520	COG0574	Belongs to the PEP-utilizing enzyme family
G7071_16525	COG0367	asparagine synthase
G7071_16550	COG0189	ligase activity
G7071_16550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G7071_16565	COG1132	(ABC) transporter
G7071_16570	COG1132	(ABC) transporter
G7071_16575	COG0107	imidazoleglycerol-phosphate synthase activity
G7071_16580	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G7071_16585	COG0596	Alpha beta hydrolase
G7071_16590	COG0789	Transcriptional regulator
G7071_16610	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G7071_16615	COG0131	Imidazoleglycerol-phosphate dehydratase
G7071_16620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G7071_16625	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G7071_16640	COG0587	DNA-directed DNA polymerase activity
G7071_16665	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G7071_16680	COG1799	cell septum assembly
G7071_16685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G7071_16705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7071_16710	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G7071_16720	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G7071_16725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G7071_16730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G7071_16735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G7071_16740	COG0768	penicillin binding
G7071_16750	COG0275	rRNA processing
G7071_16760	COG2001	Belongs to the MraZ family
G7071_16765	COG0714	Associated with various cellular activities
G7071_16785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G7071_16795	COG0587	DNA-directed DNA polymerase activity
G7071_16830	COG1233	COG1233 Phytoene dehydrogenase and related
G7071_16875	COG0741	lytic transglycosylase activity
G7071_16905	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G7071_16945	COG2197	response regulator
G7071_16980	COG1940	carbohydrate kinase activity
G7071_17000	COG0003	Pfam Anion-transporting ATPase
G7071_17045	COG4585	Histidine kinase
G7071_17080	COG0501	Belongs to the peptidase M48B family
G7071_17130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G7071_17145	COG1845	cytochrome c oxidase, subunit III
G7071_17150	COG2010	Cytochrome c
G7071_17155	COG0723	plastoquinol--plastocyanin reductase activity
G7071_17160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G7071_17185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G7071_17190	COG1104	cysteine desulfurase activity
G7071_17200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7071_17225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G7071_17230	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G7071_17240	COG0501	Belongs to the peptidase M48B family
G7071_17290	COG0612	Peptidase, M16
G7071_17295	COG1185	polyribonucleotide nucleotidyltransferase activity
G7071_17300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G7071_17320	COG0243	molybdopterin cofactor binding
G7071_17325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G7071_17330	COG1349	DNA-binding transcription factor activity
G7071_17340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7071_17340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7071_17340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7071_17345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7071_17365	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G7071_17370	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G7071_17375	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G7071_17390	COG0779	Required for maturation of 30S ribosomal subunits
G7071_17425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G7071_17430	COG0750	zinc metalloprotease
G7071_17475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G7071_17490	COG0233	cytoplasmic translational termination
G7071_17495	COG0528	UMP kinase activity
G7071_17500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G7071_17505	COG0052	Belongs to the universal ribosomal protein uS2 family
G7071_17530	COG0792	nuclease activity
G7071_17540	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G7071_17545	COG0681	Belongs to the peptidase S26 family
G7071_17550	COG0335	large ribosomal subunit rRNA binding
G7071_17555	COG0336	Belongs to the RNA methyltransferase TrmD family
G7071_17560	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G7071_17565	COG1837	Belongs to the UPF0109 family
G7071_17570	COG0228	four-way junction DNA binding
G7071_17615	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G7071_17700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G7071_17705	COG0571	ribonuclease III activity
G7071_17710	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G7071_17720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G7071_17735	COG1461	Dihydroxyacetone kinase
G7071_17740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G7071_17770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G7071_17785	COG0776	regulation of translation
G7071_17790	COG0066	3-isopropylmalate dehydratase activity
G7071_17805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G7071_17830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7071_17830	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
G7071_17870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G7071_17880	COG0156	8-amino-7-oxononanoate synthase activity
G7071_17885	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G7071_17890	COG0154	amidase activity
G7071_17895	COG0431	NADPH-dependent FMN reductase
G7071_17910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7071_17915	COG2205	protein histidine kinase activity
G7071_17915	COG3437	response regulator, receiver
G7071_17915	COG3850	Histidine kinase
G7071_17915	COG4999	Histidine kinase
G7071_17925	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7071_17925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7071_17930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G7071_17935	COG0473	3-isopropylmalate dehydrogenase activity
G7071_17960	COG2364	Membrane
G7071_17970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7071_17975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G7071_17980	COG0702	epimerase
G7071_17985	COG1131	(ABC) transporter
G7071_17995	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G7071_18010	COG2154	pterin-4-alpha-carbinolamine dehydratase
G7071_18025	COG0129	dihydroxy-acid dehydratase activity
G7071_18060	COG3845	ABC transporter
G7071_18080	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G7071_18085	COG0154	amidase activity
G7071_18090	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G7071_18095	COG1595	DNA-templated transcription, initiation
G7071_18120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G7071_18125	COG1309	transcriptional regulator
G7071_18145	COG0482	sulfurtransferase activity
G7071_18160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G7071_18165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G7071_18170	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G7071_18175	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G7071_18180	COG1530	ribonuclease E activity
G7071_18195	COG1216	Glycosyl transferase, family 2
G7071_18275	COG2205	protein histidine kinase activity
G7071_18275	COG2202	Pas domain
G7071_18280	COG0772	Belongs to the SEDS family
G7071_18285	COG0768	penicillin binding
G7071_18300	COG1077	Cell shape determining protein MreB Mrl
G7071_18310	COG0105	UTP biosynthetic process
G7071_18320	COG0285	dihydrofolate synthase activity
G7071_18330	COG0525	valine-tRNA ligase activity
G7071_18340	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G7071_18345	COG0740	serine-type endopeptidase activity
G7071_18350	COG0740	serine-type endopeptidase activity
G7071_18365	COG0544	peptidyl-prolyl cis-trans isomerase activity
G7071_18390	COG0698	ribose 5-phosphate isomerase
G7071_18410	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7071_18420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G7071_18450	COG1764	response to oxidative stress
G7071_18460	COG0824	Thioesterase
G7071_18475	COG0183	Belongs to the thiolase family
G7071_18510	COG0006	proline dipeptidase activity
G7071_18515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7071_18525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7071_18545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G7071_18590	COG0492	ferredoxin-NADP+ reductase activity
G7071_18600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G7071_18610	COG1122	ATPase activity
G7071_18645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G7071_18650	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates