locus-tag	class	description
A8A54_00020	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
A8A54_00055	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
A8A54_00060	ENOG4107Z1W	Fructose transport system kinase
A8A54_00090	ENOG4108UT2	hemolysin iii
A8A54_00100	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
A8A54_00120	ENOG41082F9	transcriptional regulator
A8A54_00130	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A8A54_00140	ENOG4105CDH	Citrulline--aspartate ligase
A8A54_00145	ENOG4106R49	Methyltransferase
A8A54_00160	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A8A54_00180	ENOG4105KZX	Pterin carbinolamine dehydratase
A8A54_00200	ENOG4108I0Y	(ABC) transporter
A8A54_00210	ENOG4105HFZ	Membrane
A8A54_00230	ENOG4107QM5	aconitate hydratase
A8A54_00240	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
A8A54_00245	ENOG41060IM	Heme exporter protein
A8A54_00255	ENOG4107QX9	Thiol disulfide interChange protein
A8A54_00260	ENOG4105C01	Dihydroxy-acid dehydratase
A8A54_00280	ENOG4105BZU	Histidine kinase
A8A54_00295	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
A8A54_00300	ENOG4108I5D	sulfate abc transporter
A8A54_00305	ENOG4105ECW	sulfate abc transporter
A8A54_00310	ENOG4108IJ6	ABC transporter
A8A54_00315	ENOG4105E2V	Glycosyltransferase 36
A8A54_00320	ENOG4107RH7	Nicotinate phosphoribosyltransferase
A8A54_00325	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A8A54_00330	ENOG4105DMQ	Methyltransferase
A8A54_00340	ENOG4106PGW	Short-chain dehydrogenase reductase Sdr
A8A54_00345	ENOG4108JQC	penicillin-binding protein 1A
A8A54_00360	ENOG4107U9H	DNA polymerase
A8A54_00365	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A8A54_00375	ENOG4105C2M	dna polymerase I
A8A54_00390	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A8A54_00405	ENOG4105C4W	S-formylglutathione hydrolase
A8A54_00415	ENOG4107YB6	acetyltransferase, (GNAT) family
A8A54_00420	ENOG4107QPD	alcohol dehydrogenase
A8A54_00430	ENOG4105K5X	acetyltransferase
A8A54_00435	ENOG4105CQ7	ATP-dependent helicase
A8A54_00445	ENOG4105TX3	Histidine kinase
A8A54_00450	ENOG4108UYB	regulatoR
A8A54_00460	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
A8A54_00465	ENOG41083MR	nifu domain-containing protein
A8A54_00475	ENOG4105C31	Tryptophanyl-tRNA synthetase
A8A54_00480	ENOG4105CJR	Integral membrane protein (MviN
A8A54_00485	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
A8A54_00490	ENOG4105C6K	Malic enzyme
A8A54_00495	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A8A54_00505	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A8A54_00510	ENOG4108RWN	rrna methyltransferase
A8A54_00515	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A8A54_00530	ENOG4105D07	Signal peptide peptidase, SppA
A8A54_00540	ENOG4105RF0	OstA family
A8A54_00545	ENOG4108IUZ	ABC transporter
A8A54_00550	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A8A54_00555	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
A8A54_00560	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
A8A54_00570	ENOG4108ZNX	Heat shock protein
A8A54_00595	ENOG4105EN6	Membrane
A8A54_00600	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A8A54_00605	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
A8A54_00610	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A8A54_00620	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A8A54_00625	ENOG4105CSA	Coproporphyrinogen iii oxidase
A8A54_00630	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A8A54_00635	ENOG41082FP	UPF0102 protein
A8A54_00640	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A8A54_00650	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
A8A54_00655	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A8A54_00670	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A8A54_00685	ENOG4105C3R	Methionine synthase
A8A54_00690	ENOG4105VJY	transcriptional regulator
A8A54_00700	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A8A54_00710	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
A8A54_00725	ENOG4108VB1	regulatoR
A8A54_00740	ENOG4105E98	transcriptional regulator DeoR family
A8A54_00745	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A8A54_00755	ENOG4105C26	Dehydrogenase
A8A54_00770	ENOG4105ETE	Transcriptional regulator (LacI family
A8A54_00775	ENOG4108JJ7	ABC transporter
A8A54_00780	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
A8A54_00785	ENOG4105ETU	transcriptional activator (TenA
A8A54_00790	ENOG4107Z6I	Thiamine biosynthesis protein
A8A54_00800	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A8A54_00830	ENOG4105DZG	Dehydrogenase
A8A54_00860	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A8A54_00870	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A8A54_00900	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A8A54_00905	ENOG4108IJ9	(ABC) transporter
A8A54_00910	ENOG4105DIA	mandelate racemase muconate lactonizing
A8A54_00915	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
A8A54_00930	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
A8A54_00940	ENOG4105DIA	mandelate racemase muconate lactonizing
A8A54_00950	ENOG4105BZU	Histidine kinase
A8A54_00955	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
A8A54_00965	ENOG41086Q3	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
A8A54_00975	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A8A54_00980	ENOG4107WAU	Protein tyrosine phosphatase
A8A54_00985	ENOG4108ZTZ	UPF0262 protein
A8A54_01000	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A8A54_01020	ENOG4105BZU	Histidine kinase
A8A54_01025	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A8A54_01030	ENOG4105BZS	acriflavin resistance protein
A8A54_01035	ENOG4107Z6I	Thiamine biosynthesis protein
A8A54_01040	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A8A54_01045	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
A8A54_01055	ENOG4105CD3	dihydroorotase
A8A54_01060	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
A8A54_01065	ENOG4108R86	Transcriptional regulator
A8A54_01070	ENOG4105M6F	mutator MutT protein
A8A54_01075	ENOG4108IJ9	(ABC) transporter
A8A54_01080	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A8A54_01100	ENOG41073TP	transcriptional regulator
A8A54_01110	ENOG4108RVA	ribokinase
A8A54_01115	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A8A54_01135	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A8A54_01145	ENOG4107SJI	Dehydrogenase
A8A54_01150	ENOG4105BZ8	glutamate synthase
A8A54_01155	ENOG4105FDR	Membrane
A8A54_01165	ENOG4107QP8	phosphohexose isomerase
A8A54_01175	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A8A54_01185	ENOG4105CEY	Amp-dependent synthetase and ligase
A8A54_01215	ENOG4105CSR	polyphosphate kinase 2
A8A54_01220	ENOG4105BZU	Histidine kinase
A8A54_01230	ENOG4105C8Y	Acetylornithine aminotransferase
A8A54_01240	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A8A54_01245	ENOG4105NWN	ApaG protein
A8A54_01260	ENOG4105ECQ	AraC Family Transcriptional Regulator
A8A54_01275	ENOG4107R73	Mate efflux family protein
A8A54_01280	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A8A54_01295	ENOG4105BZU	Histidine kinase
A8A54_01310	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A8A54_01315	ENOG4105CHM	Aminotransferase
A8A54_01320	ENOG4105D29	Helix-turn-helix type 11 domain protein
A8A54_01330	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A8A54_01335	ENOG4107BJW	polysaccharide deacetylase
A8A54_01345	ENOG4106ISJ	urease accessory protein
A8A54_01355	ENOG4105CMU	LysR family (Transcriptional regulator
A8A54_01360	ENOG4105VAW	lrga family
A8A54_01370	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
A8A54_01385	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A8A54_01390	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A8A54_01395	ENOG4108WUH	Transcriptional regulator, TetR family
A8A54_01405	ENOG4105EQK	-acetyltransferase
A8A54_01415	ENOG4105DP0	ferredoxin-NADP reductase
A8A54_01425	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
A8A54_01435	ENOG4105CTU	Proline racemase
A8A54_01440	ENOG4107QI1	Mate efflux family protein
A8A54_01455	ENOG4105S0E	allantoin catabolism protein
A8A54_01475	ENOG4105C7W	Xanthine dehydrogenase
A8A54_01495	ENOG4107QUY	Guanine deaminase
A8A54_01500	ENOG41069M3	Transcriptional regulator
A8A54_01505	ENOG41060W2	glyoxylate carboligase
A8A54_01510	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
A8A54_01515	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A8A54_01565	ENOG4105G5W	regulator Fur family
A8A54_01570	ENOG4105DHQ	Histidine kinase
A8A54_01575	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A8A54_01585	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
A8A54_01590	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A8A54_01595	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A8A54_01605	ENOG4105KUZ	arsenate reductase
A8A54_01615	ENOG4105CBP	Major Facilitator
A8A54_01635	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A8A54_01665	ENOG4105CHR	reductase
A8A54_01675	ENOG4105PGM	cation diffusion facilitator family transporter
A8A54_01680	ENOG4105CFG	Acts as a chaperone (By similarity)
A8A54_01710	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
A8A54_01715	ENOG4105VD1	ATP synthase subunit C
A8A54_01720	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A8A54_01725	ENOG4105N5Q	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
A8A54_01730	ENOG4105EW9	transcriptional regulator AsnC family
A8A54_01735	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
A8A54_01780	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A8A54_01805	ENOG4105EAH	synthase
A8A54_01820	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A8A54_01825	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A8A54_01840	ENOG4108IPT	Naphthoate synthase
A8A54_01845	ENOG4105CSU	acyl-Coa dehydrogenase
A8A54_01860	ENOG4106TD9	Diguanylate cyclase
A8A54_01870	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A8A54_01875	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
A8A54_01890	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A8A54_01895	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A8A54_01925	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A8A54_01930	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A8A54_01940	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A8A54_01945	ENOG4107T5V	SNARE associated Golgi
A8A54_01950	ENOG4105Y3U	Transglycosylase-associated protein
A8A54_01960	ENOG4105EUB	pirin domain protein
A8A54_01965	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A8A54_01995	ENOG4108URH	decarboxylase
A8A54_02000	ENOG41069B0	Membrane-bound lysozyme-inhibitor of c-type lysozyme
A8A54_02005	ENOG4108WZM	domain protein
A8A54_02015	ENOG4108JJ7	ABC transporter
A8A54_02020	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
A8A54_02025	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
A8A54_02035	ENOG4105UBK	short-chain dehydrogenase reductase
A8A54_02040	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A8A54_02055	ENOG4105CDU	Replicative dna helicase
A8A54_02065	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A8A54_02070	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A8A54_02080	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A8A54_02085	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A8A54_02090	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A8A54_02100	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A8A54_02105	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A8A54_02110	ENOG4105HHA	aminodeoxychorismate lyase
A8A54_02115	ENOG4105DSJ	YicC domain protein
A8A54_02125	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A8A54_02150	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A8A54_02160	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
A8A54_02165	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A8A54_02180	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
A8A54_02185	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
A8A54_02195	ENOG4108R6F	Surfeit locus 1 family protein
A8A54_02200	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A8A54_02205	ENOG4105CUV	Homoserine Kinase
A8A54_02240	ENOG4108UJU	UPF0301 protein
A8A54_02245	ENOG4105BZU	Histidine kinase
A8A54_02250	ENOG4105D9U	N-acetyltransferase
A8A54_02255	ENOG4105C1V	Peptidase, M16
A8A54_02260	ENOG4105D98	threonine synthase
A8A54_02270	ENOG41066DG	(EAL) domain protein
A8A54_02290	ENOG4105CEC	DNA methylase N-4 N-6
A8A54_02330	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A8A54_02355	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A8A54_02380	ENOG4107ZYJ	bioY protein
A8A54_02390	ENOG4105VT2	5-hydroxyisourate hydrolase
A8A54_02400	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
A8A54_02405	ENOG4105C26	Dehydrogenase
A8A54_02410	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
A8A54_02415	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
A8A54_02420	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A8A54_02425	ENOG4107QUT	magnesium and cobalt transport protein CorA
A8A54_02430	ENOG4105JXH	GntR family transcriptional regulator
A8A54_02435	ENOG4105DJ2	Major Facilitator Superfamily
A8A54_02445	ENOG4105D7A	ATP-binding protein
A8A54_02450	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
A8A54_02460	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A8A54_02465	ENOG4105TAV	cytochrome C
A8A54_02470	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
A8A54_02490	ENOG4105E0X	reductase
A8A54_02495	ENOG4108YXV	Transcriptional regulator
A8A54_02515	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A8A54_02520	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
A8A54_02530	ENOG4105BZU	Histidine kinase
A8A54_02560	ENOG4108JQC	penicillin-binding protein 1A
A8A54_02655	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A8A54_02660	ENOG41062D9	Histidine kinase
A8A54_02670	ENOG4106FI7	cytochrome c-type biogenesis protein
A8A54_02675	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
A8A54_02680	ENOG4105DA4	cytochrome c-type biogenesis protein
A8A54_02685	ENOG4105KWW	Biogenesis protein
A8A54_02690	ENOG4105C0H	protease
A8A54_02695	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A8A54_02700	ENOG4105JJR	Histidine kinase
A8A54_02705	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
A8A54_02710	ENOG4105BZU	Histidine kinase
A8A54_02715	ENOG4105CD8	aminopeptidase N
A8A54_02730	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A8A54_02735	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A8A54_02745	ENOG4105FYV	Amp nucleosidase
A8A54_02750	ENOG4105CYM	Glutathione S-transferase
A8A54_02785	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A8A54_02815	ENOG4105CE9	30S ribosomal protein S2
A8A54_02820	ENOG4107SC1	transglycosylase
A8A54_02830	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A8A54_02840	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A8A54_02850	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A8A54_02855	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
A8A54_02860	ENOG4105D4P	Coproporphyrinogen iii oxidase
A8A54_02865	ENOG4105EU0	Major facilitator Superfamily
A8A54_02870	ENOG4105R1U	AraC Family Transcriptional Regulator
A8A54_02880	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A8A54_02885	ENOG4105C3F	Signal peptidase i
A8A54_02890	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A8A54_02910	ENOG4108R7K	Metal Dependent Phosphohydrolase
A8A54_02915	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
A8A54_02920	ENOG4105CD3	dihydroorotase
A8A54_02930	ENOG4105ECQ	AraC Family Transcriptional Regulator
A8A54_02970	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A8A54_02980	ENOG4105DR5	peptidase
A8A54_02985	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A8A54_02990	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A8A54_02995	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A8A54_03015	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A8A54_03030	ENOG4105C5H	ABC transporter
A8A54_03040	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A8A54_03050	ENOG4108ZAF	Molybdopterin
A8A54_03055	ENOG4105M00	molybdopterin converting factor, subunit 1
A8A54_03060	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A8A54_03095	ENOG4105D6S	protein involved in catabolism of external DNA
A8A54_03105	ENOG4107QY8	reductase
A8A54_03115	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A8A54_03120	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A8A54_03125	ENOG4105C02	permease
A8A54_03145	ENOG4105CHR	reductase
A8A54_03165	ENOG4108NIW	Leucine export protein LeuE
A8A54_03180	ENOG4105C28	cystathionine
A8A54_03185	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
A8A54_03190	ENOG4107QXX	ABC transporter
A8A54_03195	ENOG4105EZ7	amino acid ABC transporter
A8A54_03200	ENOG4105DRP	amino acid AbC transporter
A8A54_03205	ENOG4105CDA	abc transporter atp-binding protein
A8A54_03220	ENOG4105NPE	arsR family transcriptional regulator
A8A54_03255	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
A8A54_03265	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
A8A54_03270	ENOG4105C9M	aspartyl-trna synthetase
A8A54_03280	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A8A54_03295	ENOG4105D52	delta-aminolevulinic acid dehydratase
A8A54_03315	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
A8A54_03320	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A8A54_03325	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A8A54_03330	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A8A54_03340	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A8A54_03345	ENOG4107XZX	Involved in the transcription termination process (By similarity)
A8A54_03350	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
A8A54_03355	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A8A54_03370	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
A8A54_03375	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A8A54_03380	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A8A54_03385	ENOG4105WJX	transcriptional regulator MERR family
A8A54_03390	ENOG4105KPY	Small multidrug resistance protein
A8A54_03395	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
A8A54_03420	ENOG4105KK4	UPF0060 membrane protein
A8A54_03430	ENOG4105D3Q	Sugar transferase
A8A54_03435	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A8A54_03460	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
A8A54_03470	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A8A54_03475	ENOG4105CYW	agmatinase
A8A54_03480	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
A8A54_03485	ENOG4108UJD	30S ribosomal protein S9
A8A54_03500	ENOG4105K4P	CoA-binding domain protein
A8A54_03515	ENOG4105C26	Dehydrogenase
A8A54_03520	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A8A54_03535	ENOG4107R9N	ABC transporter
A8A54_03540	ENOG4105CNN	ABC, transporter
A8A54_03550	ENOG4105D4B	ABC, transporter
A8A54_03555	ENOG4107FB0	transcriptional regulator DeoR family
A8A54_03580	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A8A54_03590	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A8A54_03595	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A8A54_03600	ENOG4105GKE	subunit e
A8A54_03605	ENOG4107QIZ	NADH dehydrogenase
A8A54_03610	ENOG4107R0R	NADH dehydrogenase subunit g
A8A54_03615	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A8A54_03620	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A8A54_03625	ENOG4105DF2	NADH dehydrogenase subunit j
A8A54_03630	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A8A54_03635	ENOG4105D65	subunit l
A8A54_03640	ENOG4105C8S	subunit m
A8A54_03645	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A8A54_03650	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A8A54_03675	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A8A54_03695	ENOG4105C0B	DNA polymerase III (alpha subunit)
A8A54_03705	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
A8A54_03710	ENOG4105KVH	Transcriptional regulator
A8A54_03730	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A8A54_03735	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A8A54_03745	ENOG4105C2C	drug resistance transporter, Bcr CflA
A8A54_03760	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
A8A54_03765	ENOG4107SQD	Transcriptional regulator, GntR family
A8A54_03790	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
A8A54_03815	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
A8A54_03825	ENOG4105C83	adenylosuccinate lyase
A8A54_03830	ENOG4105DJV	ribulose-phosphate 3-epimerase
A8A54_03845	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A8A54_03850	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A8A54_03855	ENOG4105J3Q	acyl carrier protein
A8A54_03870	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
A8A54_03875	ENOG4108TXN	phosphonate metabolism protein
A8A54_03880	ENOG4105FD8	phosphonate metabolism protein PhnM
A8A54_03885	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
A8A54_03890	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A8A54_03900	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
A8A54_03905	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
A8A54_03910	ENOG4108XM1	transcriptional regulator AsnC family
A8A54_03925	ENOG4108UQD	Sel1 domain protein repeat-containing protein
A8A54_03940	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A8A54_03945	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
A8A54_03950	ENOG4105C75	arginyL-tRNA synthetase
A8A54_03960	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
A8A54_03965	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
A8A54_03970	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A8A54_03975	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A8A54_03985	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A8A54_03990	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A8A54_03995	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A8A54_04000	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A8A54_04005	ENOG4108K5P	(LipO)protein
A8A54_04035	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
A8A54_04060	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A8A54_04070	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A8A54_04085	ENOG4106ECF	Uncharacterized protein conserved in bacteria (DUF2155)
A8A54_04090	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
A8A54_04095	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A8A54_04100	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A8A54_04115	ENOG4105D0M	Protease HtpX homolog
A8A54_04120	ENOG4105CHM	Aminotransferase
A8A54_04125	ENOG4105C03	ribonuclease
A8A54_04135	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A8A54_04145	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A8A54_04155	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A8A54_04175	ENOG4105DHZ	alpha beta
A8A54_04180	ENOG4105C3J	Cysteine desulfurase
A8A54_04190	ENOG4105C3K	feS assembly ATPase SufC
A8A54_04205	ENOG4105VG1	fes assembly suf system protein
A8A54_04225	ENOG4105C1J	atp-dependent rna helicase
A8A54_04235	ENOG4108Z4V	iron-sulfur cluster assembly
A8A54_04250	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A8A54_04275	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A8A54_04280	ENOG4108TGY	Glutathione S-transferase
A8A54_04295	ENOG4106TNF	Periplasmic binding protein
A8A54_04305	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A8A54_04325	ENOG4107GFK	fumarate
A8A54_04330	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
A8A54_04340	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
A8A54_04345	ENOG4105C5H	ABC transporter
A8A54_04350	ENOG4105CHR	reductase
A8A54_04355	ENOG4105D01	(LipO)protein
A8A54_04540	ENOG4107QJR	hflk protein
A8A54_04555	ENOG4105MGM	doxx family
A8A54_04570	ENOG4107TE5	Lipid kinase
A8A54_04575	ENOG4105K6T	rare lipoprotein A
A8A54_04580	ENOG4105DZ1	carboxypeptidase
A8A54_04590	ENOG4107QRG	dna polymerase iii
A8A54_04600	ENOG4105F8V	Hydrolase, tatD family
A8A54_04605	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A8A54_04615	ENOG4105EI2	Pseudouridine synthase
A8A54_04625	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A8A54_04635	ENOG4105C5F	glutamine synthetase
A8A54_04640	ENOG4108YZA	Nitrogen regulatory protein pii
A8A54_04645	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A8A54_04650	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A8A54_04670	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
A8A54_04680	ENOG4105C4K	Nad synthetase
A8A54_04685	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A8A54_04690	ENOG4105C6K	Malic enzyme
A8A54_04695	ENOG4105BZN	citrate synthase
A8A54_04705	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
A8A54_04710	ENOG4107S8C	mandelate racemase muconate lactonizing
A8A54_04715	ENOG4105CY3	ABC transporter, permease
A8A54_04720	ENOG4105DHJ	ABC, transporter
A8A54_04740	ENOG4107Z7P	Ferredoxin
A8A54_04745	ENOG4105CAY	ferredoxin--nadp reductase
A8A54_04745	ENOG4105CAY	ferredoxin--nadp reductase
A8A54_04755	ENOG4105EEI	dihydropteroate synthase
A8A54_04765	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A8A54_04775	ENOG4106K28	UPF0283 membrane protein
A8A54_04780	ENOG4105CM6	amino acid regulated cytosolic protein
A8A54_04790	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A8A54_04815	ENOG4105CUY	Mechanosensitive ion channel
A8A54_04825	ENOG4107RTZ	reductase
A8A54_04845	ENOG4107TH8	cina domain protein
A8A54_04855	ENOG4105C7B	Threonine dehydratase
A8A54_04860	ENOG4105C1J	atp-dependent rna helicase
A8A54_04870	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A8A54_04875	ENOG4105KHC	sulfurtransferase
A8A54_04885	ENOG4105BZU	Histidine kinase
A8A54_04890	ENOG4105CYC	Transferase
A8A54_04900	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A8A54_04905	ENOG4105DHU	Bile acid
A8A54_04910	ENOG4105CMR	udp-glucose 4-epimerase
A8A54_04915	ENOG4105DXN	mazG family
A8A54_04940	ENOG4105DZ1	carboxypeptidase
A8A54_04955	ENOG4105EUJ	GTP cyclohydrolase i
A8A54_04960	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A8A54_04965	ENOG4105D78	K07001 NTE family protein
A8A54_04980	ENOG4105X1Q	TOBE domain protein
A8A54_04990	ENOG4105C1G	acyl-Coa dehydrogenase
A8A54_04995	ENOG4105ETT	transcriptional Regulator, LysR family
A8A54_05000	ENOG4105DEN	Luciferase family
A8A54_05005	ENOG4105BZS	acriflavin resistance protein
A8A54_05010	ENOG410624X	efflux transporter, rnd family, mfp subunit
A8A54_05025	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
A8A54_05030	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A8A54_05035	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A8A54_05040	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A8A54_05050	ENOG41081FY	multiple antibiotic resistance (MarC)-related
A8A54_05065	ENOG4106ZX3	phosphonate ABC transporter, periplasmic phosphonate-binding protein
A8A54_05070	ENOG4105D5T	phosphonate abc transporter
A8A54_05080	ENOG4105FD8	phosphonate metabolism protein PhnM
A8A54_05090	ENOG4105HRV	phosphonate c-p lyase system protein phnl
A8A54_05095	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
A8A54_05135	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A8A54_05140	ENOG4108T58	Mg2 transport protein CorA
A8A54_05155	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A8A54_05160	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A8A54_05165	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A8A54_05170	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
A8A54_05180	ENOG4105C1A	potassium transporter peripheral membrane
A8A54_05185	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A8A54_05190	ENOG4105ES5	Histidine kinase
A8A54_05195	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A8A54_05200	ENOG4105CUX	Signal transduction histidine kinase
A8A54_05210	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A8A54_05215	ENOG4107TH8	cina domain protein
A8A54_05220	ENOG4108Z1B	Cyclase dehydrase
A8A54_05225	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A8A54_05235	ENOG4107QN2	dihydrolipoyl dehydrogenase
A8A54_05245	ENOG4105C7S	Dehydrogenase
A8A54_05250	ENOG4105CPP	Dehydrogenase, E1 component
A8A54_05255	ENOG4108JYK	Dehydrogenase
A8A54_05260	ENOG4106ABQ	septum formation initiator
A8A54_05265	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
A8A54_05270	ENOG4108NTW	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
A8A54_05275	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A8A54_05280	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
A8A54_05290	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A8A54_05300	ENOG4107EJC	Preprotein translocase subunit SecG
A8A54_05315	ENOG4107QYG	anthranilate phosphoribosyltransferase
A8A54_05320	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A8A54_05325	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A8A54_05330	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A8A54_05335	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A8A54_05350	ENOG4105BZN	citrate synthase
A8A54_05355	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A8A54_05365	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A8A54_05375	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A8A54_05380	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8A54_05400	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A8A54_05405	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A8A54_05410	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A8A54_05415	ENOG4105CE9	30S ribosomal protein S2
A8A54_05430	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
A8A54_05440	ENOG4105K59	histidine triad (HIT) protein
A8A54_05460	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
A8A54_05465	ENOG4105DZ1	carboxypeptidase
A8A54_05480	ENOG4105EJQ	L-serine dehydratase
A8A54_05515	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
A8A54_05525	ENOG4105CFF	transcriptional regulator
A8A54_05530	ENOG4107QX3	carboxylase
A8A54_05535	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A8A54_05560	ENOG4105CV8	reductase
A8A54_05565	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A8A54_05570	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A8A54_05575	ENOG4107R7Y	intracellular protease Pfpi family
A8A54_05620	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A8A54_05625	ENOG4108ZG0	Ompa motb domain protein
A8A54_05640	ENOG4105D1H	recombination factor protein RarA
A8A54_05645	ENOG4105C0H	protease
A8A54_05650	ENOG4108ZT0	50S ribosomal protein l17
A8A54_05655	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A8A54_05660	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A8A54_05665	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A8A54_05670	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A8A54_05675	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A8A54_05680	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A8A54_05685	ENOG41084HQ	50S ribosomal protein L30
A8A54_05690	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A8A54_05695	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A8A54_05705	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A8A54_05710	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A8A54_05715	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A8A54_05720	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A8A54_05725	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A8A54_05730	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A8A54_05735	ENOG41083MP	50s ribosomal protein l29
A8A54_05740	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A8A54_05745	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A8A54_05755	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A8A54_05760	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A8A54_05765	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A8A54_05770	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A8A54_05775	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A8A54_05780	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A8A54_05790	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A8A54_05795	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A8A54_05800	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A8A54_05815	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A8A54_05820	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A8A54_05825	ENOG4108VZM	50s ribosomal protein L10
A8A54_05830	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A8A54_05835	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A8A54_05870	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A8A54_05875	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A8A54_05895	ENOG4108Z0R	Transferase
A8A54_05915	ENOG4105D7W	serine acetyltransferase
A8A54_05930	ENOG4105VEQ	Cold shock protein
A8A54_05945	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A8A54_05950	ENOG4105CBT	Fructose-1,6-bisphosphatase
A8A54_05955	ENOG4105C5H	ABC transporter
A8A54_05960	ENOG4105D6E	homoserine dehydrogenase
A8A54_05965	ENOG4105CHM	Aminotransferase
A8A54_05995	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A8A54_06000	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A8A54_06005	ENOG4105W5Q	DNA repair protein (RadC
A8A54_06015	ENOG4108IGT	Dipeptidase
A8A54_06020	ENOG4105DEF	Extracellular solute-binding protein, family 5
A8A54_06025	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8A54_06030	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_06035	ENOG4105C3U	ABC transporter
A8A54_06040	ENOG4108JQ7	(ABC) transporter
A8A54_06045	ENOG4105Q26	Siderophore-interacting protein
A8A54_06050	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
A8A54_06060	ENOG41081F0	Precorrin-8x methylmutase
A8A54_06065	ENOG4105DVK	Precorrin-2 c20-methyltransferase
A8A54_06085	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
A8A54_06095	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
A8A54_06105	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
A8A54_06115	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
A8A54_06120	ENOG4105QUC	reductase
A8A54_06130	ENOG4108IND	Tetr family transcriptional regulator
A8A54_06190	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
A8A54_06205	ENOG4108VDT	Glycosyl transferase family protein
A8A54_06225	ENOG4105ECQ	AraC Family Transcriptional Regulator
A8A54_06230	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A8A54_06240	ENOG4105EGS	Mechanosensitive ion channel
A8A54_06255	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A8A54_06270	ENOG4105ECW	sulfate abc transporter
A8A54_06275	ENOG4108I5D	sulfate abc transporter
A8A54_06280	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
A8A54_06290	ENOG4105EE5	Membrane protein terC
A8A54_06295	ENOG4108KF1	Membrane
A8A54_06315	ENOG4105NWF	RbsD or FucU transport
A8A54_06325	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
A8A54_06330	ENOG4105C2J	ABC transporter
A8A54_06335	ENOG41062B0	ABC transporter, permease
A8A54_06345	ENOG4105CIB	oxidoreductase Domain protein
A8A54_06350	ENOG4105E0A	ABC, transporter
A8A54_06355	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
A8A54_06365	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A8A54_06370	ENOG4105CMI	transporter
A8A54_06375	ENOG4105CJ1	ABC, transporter
A8A54_06380	ENOG4105D0S	secretion protein (HlyD
A8A54_06385	ENOG4105F32	YngK protein
A8A54_06400	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A8A54_06415	ENOG4105W6J	BA14K family
A8A54_06420	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A8A54_06425	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A8A54_06435	ENOG4105DFH	Transport of potassium into the cell (By similarity)
A8A54_06440	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
A8A54_06450	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
A8A54_06460	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
A8A54_06480	ENOG4105C7K	acetolactate synthase
A8A54_06490	ENOG4105EAC	phosphoserine phosphatase
A8A54_06495	ENOG4108YYQ	gCN5-related N-acetyltransferase
A8A54_06500	ENOG4105C0H	protease
A8A54_06510	ENOG4105EPW	hflc protein
A8A54_06515	ENOG4107RIZ	hflk protein
A8A54_06525	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A8A54_06540	ENOG4105C2C	drug resistance transporter, Bcr CflA
A8A54_06575	ENOG4105CQB	FAD linked oxidase domain protein
A8A54_06590	ENOG4105C4R	Atp-dependent dna helicase
A8A54_06605	ENOG4108ZX6	Electron transport protein SCO1 SenC
A8A54_06635	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A8A54_06645	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8A54_06650	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A8A54_06655	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A8A54_06660	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A8A54_06665	ENOG4108UFP	Essential cell division protein (By similarity)
A8A54_06670	ENOG4105CPF	Cell wall formation (By similarity)
A8A54_06680	ENOG4105DFU	Cell wall formation (By similarity)
A8A54_06685	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A8A54_06695	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A8A54_06700	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A8A54_06725	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A8A54_06730	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
A8A54_06735	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A8A54_06750	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
A8A54_06755	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
A8A54_06775	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A8A54_06795	ENOG4105SYT	Methylenetetrahydrofolate reductase
A8A54_06800	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A8A54_06810	ENOG4105CSH	Transporter
A8A54_06815	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A8A54_06825	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
A8A54_06830	ENOG4105CKK	Glycosyl transferase, family 2
A8A54_06840	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A8A54_06855	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A8A54_06860	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
A8A54_06865	ENOG4108RWI	nicotinamidase
A8A54_06910	ENOG4105VDW	Csbd family
A8A54_06920	ENOG4108MXK	alkaline phosphatase isozyme conversion
A8A54_06930	ENOG4105MPN	Membrane
A8A54_06955	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A8A54_06960	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A8A54_06965	ENOG4105EAM	Na Pi-cotransporter
A8A54_06975	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A8A54_06980	ENOG4105CGZ	zinc metallopeptidase
A8A54_07010	ENOG4108IG5	Transcriptional regulator
A8A54_07015	ENOG4108RXX	maleylacetoacetate isomerase
A8A54_07035	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
A8A54_07040	ENOG4105EG2	ABC transporter, permease
A8A54_07050	ENOG4105CBN	LysR family transcriptional regulator
A8A54_07055	ENOG4105C3M	thioredoxin reductase
A8A54_07060	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A8A54_07065	ENOG4105F7P	transcriptional regulator AsnC family
A8A54_07075	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A8A54_07100	ENOG4105NAU	thioesterase Superfamily protein
A8A54_07110	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A8A54_07120	ENOG4105KVH	Transcriptional regulator
A8A54_07125	ENOG4105E4C	Lytic transglycosylase catalytic
A8A54_07140	ENOG4105C5X	domain protein
A8A54_07155	ENOG41090HR	transcriptional regulator
A8A54_07160	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A8A54_07165	ENOG4105E0F	Histidine kinase
A8A54_07170	ENOG4105WMR	Protein CrcB homolog
A8A54_07175	ENOG4108Z7R	Chaperone CsaA
A8A54_07190	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A8A54_07200	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A8A54_07230	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A8A54_07240	ENOG4105NAE	bifunctional deaminase-reductase domain protein
A8A54_07245	ENOG4105C3G	gtp-binding protein
A8A54_07250	ENOG4108ZMQ	domain protein
A8A54_07260	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A8A54_07265	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A8A54_07275	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A8A54_07280	ENOG4105BZ1	(ABC) transporter
A8A54_07285	ENOG4105BZ1	(ABC) transporter
A8A54_07290	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A8A54_07305	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
A8A54_07315	ENOG4105YCT	UPF0386 protein
A8A54_07330	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A8A54_07335	ENOG4105P8F	nudix hydrolase
A8A54_07345	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A8A54_07370	ENOG4105CHF	Glutathione S-transferase
A8A54_07380	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A8A54_07405	ENOG4105CRQ	synthase (Component I)
A8A54_07410	ENOG4105EW9	transcriptional regulator AsnC family
A8A54_07450	ENOG4107SQ8	Glycine betaine
A8A54_07455	ENOG4108IJ7	Glycine betaine
A8A54_07460	ENOG4108JQ7	(ABC) transporter
A8A54_07470	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_07475	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8A54_07480	ENOG4105DEF	Extracellular solute-binding protein, family 5
A8A54_07495	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A8A54_07525	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
A8A54_07535	ENOG4105D29	Helix-turn-helix type 11 domain protein
A8A54_07545	ENOG4108KK1	membrane protein AbrB duplication
A8A54_07550	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A8A54_07615	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A8A54_07620	ENOG4105WAB	arsR family transcriptional regulator
A8A54_07625	ENOG4105BZM	domain protein
A8A54_07630	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_07640	ENOG4107RUE	extracellular solute-binding protein family 1
A8A54_07645	ENOG4105CJP	fad dependent oxidoreductase
A8A54_07650	ENOG4105ETT	transcriptional Regulator, LysR family
A8A54_07655	ENOG4105E32	cytoplasmic protein
A8A54_07660	ENOG4105C26	Dehydrogenase
A8A54_07675	ENOG4105BZS	acriflavin resistance protein
A8A54_07680	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A8A54_07695	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
A8A54_07700	ENOG4105DMF	Dehydrogenase
A8A54_07720	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A8A54_07735	ENOG4105EW9	transcriptional regulator AsnC family
A8A54_07745	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A8A54_07760	ENOG4105CI2	imidazolone-5-propionate hydrolase
A8A54_07765	ENOG4105C84	Histidine ammonia-lyase
A8A54_07775	ENOG4105CGP	Urocanate hydratase
A8A54_07780	ENOG4105DWD	nucleoside recognition domain protein
A8A54_07785	ENOG41090B9	response to stress
A8A54_07795	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A8A54_07805	ENOG4105F0I	Aminotransferase
A8A54_07810	ENOG4108HWW	ABC transporter
A8A54_07820	ENOG4105DFW	ABC transporter
A8A54_07825	ENOG4108RTU	Aldolase
A8A54_07830	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
A8A54_07835	ENOG4105C01	Dihydroxy-acid dehydratase
A8A54_07850	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
A8A54_07855	ENOG4105C2J	ABC transporter
A8A54_07860	ENOG4107R9N	ABC transporter
A8A54_07865	ENOG41062B0	ABC transporter, permease
A8A54_07870	ENOG4107EJG	GntR family transcriptional regulator
A8A54_07890	ENOG4105CHU	acetyl-coa acetyltransferase
A8A54_07900	ENOG4105C7K	acetolactate synthase
A8A54_07905	ENOG4105EJC	lysr family transcriptional regulator
A8A54_07915	ENOG4105C0Z	ABC transporter
A8A54_07920	ENOG4108IV0	ABC, transporter
A8A54_07925	ENOG4105C32	Amino acid ABC transporter (Permease)
A8A54_07940	ENOG4105D01	(LipO)protein
A8A54_07950	ENOG4108UMI	ABC transporter, permease
A8A54_07965	ENOG4105K5G	30S ribosomal protein S21
A8A54_07980	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
A8A54_07990	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A8A54_07995	ENOG4105W8H	transhydrogenase (subunit alpha
A8A54_08000	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A8A54_08025	ENOG4105CHR	reductase
A8A54_08030	ENOG4108Z86	Glutamine amidotransferase
A8A54_08035	ENOG4105C5I	Dehydrogenase
A8A54_08040	ENOG4105ETE	Transcriptional regulator (LacI family
A8A54_08045	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
A8A54_08055	ENOG4105CKI	cobalamin synthesis protein
A8A54_08065	ENOG4105FBA	Phospholipase Carboxylesterase
A8A54_08070	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
A8A54_08075	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
A8A54_08085	ENOG4105M4H	endoribonuclease L-psp
A8A54_08095	ENOG4105VG0	50S ribosomal protein l34
A8A54_08130	ENOG4105NX3	Membrane
A8A54_08140	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
A8A54_08160	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A8A54_08175	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A8A54_08180	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A8A54_08185	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A8A54_08190	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A8A54_08205	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A8A54_08220	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A8A54_08230	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A8A54_08240	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
A8A54_08245	ENOG4108Z5K	methylglyoxal synthase
A8A54_08265	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A8A54_08280	ENOG4107RGH	Aldehyde dehydrogenase
A8A54_08290	ENOG4105DZQ	phospholipase D Transphosphatidylase
A8A54_08300	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
A8A54_08310	ENOG4108KPJ	rna polymerase sigma factor
A8A54_08315	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A8A54_08320	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A8A54_08325	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A8A54_08330	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A8A54_08335	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A8A54_08340	ENOG41066XQ	SlyX
A8A54_08350	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A8A54_08415	ENOG4105C26	Dehydrogenase
A8A54_08440	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
A8A54_08445	ENOG4107QP3	malate synthase g
A8A54_08455	ENOG4108R6G	acetyltransferase
A8A54_08465	ENOG4105CHH	sulfate transporter
A8A54_08470	ENOG4105CSH	Transporter
A8A54_08490	ENOG4108XM1	transcriptional regulator AsnC family
A8A54_08495	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
A8A54_08500	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
A8A54_08505	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A8A54_08510	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A8A54_08520	ENOG4108ZZF	transport protein (ExbD)
A8A54_08540	ENOG4105RAK	Histidine kinase
A8A54_08555	ENOG41074H6	response regulator
A8A54_08595	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A8A54_08600	ENOG4105F0N	pyrophosphate phospho-hydrolase
A8A54_08630	ENOG4105C09	Bile acid
A8A54_08640	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A8A54_08645	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A8A54_08670	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
A8A54_08680	ENOG4108ZZF	transport protein (ExbD)
A8A54_08685	ENOG4105E02	MotA TolQ exbB proton channel
A8A54_08690	ENOG4107YD3	Thioesterase
A8A54_08695	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A8A54_08700	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A8A54_08705	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A8A54_08740	ENOG4105ECY	inositol monophosphatase
A8A54_08750	ENOG4105UYK	outer membrane protein a
A8A54_08755	ENOG4105BZ1	(ABC) transporter
A8A54_08760	ENOG41082FS	50S ribosomal protein L31
A8A54_08770	ENOG4105CDY	transcriptional regulatory protein
A8A54_08780	ENOG4107ZYJ	bioY protein
A8A54_08790	ENOG4105D48	metallophosphoesterase
A8A54_08845	ENOG4107R1Y	fructose-bisphosphate aldolase
A8A54_08850	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A8A54_08855	ENOG4105CHR	reductase
A8A54_08865	ENOG4108V4B	ThiJ pfpI
A8A54_08880	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A8A54_08905	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A8A54_08910	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A8A54_08920	ENOG4105M0T	TPR Repeat-Containing Protein
A8A54_08925	ENOG4105CA9	Pyruvate kinase
A8A54_08940	ENOG4105Y2X	UPF0335 protein
A8A54_08945	ENOG4105CPC	Aldo Keto reductase
A8A54_08950	ENOG4105C5H	ABC transporter
A8A54_08965	ENOG4105DP9	ABC transporter
A8A54_08975	ENOG4107T0D	ABC, transporter
A8A54_08980	ENOG4105ERG	peptidase m48, ste24p
A8A54_08985	ENOG4108RPX	mosc domain containing protein
A8A54_08990	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A8A54_09000	ENOG4108Z4U	Ferredoxin
A8A54_09015	ENOG4105CHU	acetyl-coa acetyltransferase
A8A54_09025	ENOG41082R8	50S ribosomal protein l32
A8A54_09035	ENOG4105CTB	Polyprenyl synthetase
A8A54_09040	ENOG4107YPT	transcriptional regulator
A8A54_09050	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A8A54_09060	ENOG4106UW1	Major Facilitator superfamily
A8A54_09070	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
A8A54_09090	ENOG4108IV0	ABC, transporter
A8A54_09095	ENOG4105C0Z	ABC transporter
A8A54_09100	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
A8A54_09105	ENOG4105C32	Amino acid ABC transporter (Permease)
A8A54_09115	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A8A54_09135	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A8A54_09140	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A8A54_09145	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A8A54_09150	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A8A54_09165	ENOG4105C25	Primosomal protein n'
A8A54_09170	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A8A54_09190	ENOG4105DFA	alanine racemase domain protein
A8A54_09200	ENOG4105P0T	Usg family
A8A54_09205	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A8A54_09225	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A8A54_09235	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A8A54_09240	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A8A54_09245	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
A8A54_09250	ENOG4105DEU	major facilitator superfamily
A8A54_09255	ENOG4105C7I	Dehydrogenase
A8A54_09265	ENOG4105HA9	of methanol dehydrogenase type
A8A54_09270	ENOG4108V0P	LemA family
A8A54_09285	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
A8A54_09290	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A8A54_09295	ENOG4105DAA	L-lactate
A8A54_09305	ENOG4107B2H	carbonic anhydrase
A8A54_09310	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
A8A54_09320	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
A8A54_09330	ENOG4105C26	Dehydrogenase
A8A54_09350	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A8A54_09355	ENOG4105CN1	protease
A8A54_09380	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A8A54_09395	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A8A54_09400	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A8A54_09405	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A8A54_09420	ENOG4105K46	50S ribosomal protein l27
A8A54_09425	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A8A54_09435	ENOG4108YYH	Nadph-dependent fmn reductase
A8A54_09440	ENOG4105D3G	Pseudouridine synthase
A8A54_09445	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
A8A54_09455	ENOG4107QJQ	Mate efflux family protein
A8A54_09460	ENOG4108K3A	Glutathione S-transferase
A8A54_09500	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_09505	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8A54_09510	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
A8A54_09520	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A8A54_09535	ENOG4105CJP	fad dependent oxidoreductase
A8A54_09540	ENOG4105C26	Dehydrogenase
A8A54_09555	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
A8A54_09565	ENOG4108IG5	Transcriptional regulator
A8A54_09575	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A8A54_09590	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A8A54_09600	ENOG4105C5Q	Transcriptional regulator
A8A54_09615	ENOG4105KXX	peptidase s58 dmpa
A8A54_09630	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A8A54_09640	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
A8A54_09645	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
A8A54_09660	ENOG4107TK4	histidinol-phosphate phosphatase
A8A54_09665	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
A8A54_09670	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A8A54_09690	ENOG4106H78	methyltransferase
A8A54_09700	ENOG4108Z6B	deaminase
A8A54_09705	ENOG4105DS1	cytochrome b561
A8A54_09725	ENOG4105DTN	riboflavin biosynthesis protein ribF
A8A54_09735	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A8A54_09740	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A8A54_09760	ENOG4105C9Q	fumarate hydratase class II
A8A54_09765	ENOG4108VBZ	doxx family
A8A54_09775	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A8A54_09795	ENOG4108R3E	Dna-3-methyladenine glycosylase i
A8A54_09800	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
A8A54_09805	ENOG4105CV8	reductase
A8A54_09815	ENOG4105F7P	transcriptional regulator AsnC family
A8A54_09820	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A8A54_09825	ENOG4105EU8	FAD linked oxidase domain protein
A8A54_09830	ENOG4105CQB	FAD linked oxidase domain protein
A8A54_09835	ENOG4105EJC	lysr family transcriptional regulator
A8A54_09845	ENOG41073TP	transcriptional regulator
A8A54_09875	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
A8A54_09880	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A8A54_09905	ENOG4108PXI	ErfK YbiS YcfS YnhG
A8A54_09910	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A8A54_10050	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A8A54_10080	ENOG4105C2W	permease
A8A54_10085	ENOG4108HWW	ABC transporter
A8A54_10090	ENOG4105C2J	ABC transporter
A8A54_10095	ENOG4105DFW	ABC transporter
A8A54_10100	ENOG4105ETE	Transcriptional regulator (LacI family
A8A54_10105	ENOG4105CMG	Carbohydrate kinase
A8A54_10110	ENOG4105C93	Xylose Isomerase
A8A54_10115	ENOG4105DIJ	Phosphoethanolamine transferase
A8A54_10130	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A8A54_10135	ENOG4105CNN	ABC, transporter
A8A54_10150	ENOG4105BZU	Histidine kinase
A8A54_10155	ENOG4105BZU	Histidine kinase
A8A54_10160	ENOG4107SFI	Major Facilitator superfamily
A8A54_10170	ENOG4105CBX	hi0933 family
A8A54_10185	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A8A54_10195	ENOG4105IQ5	FAD linked oxidase domain protein
A8A54_10205	ENOG4105BZU	Histidine kinase
A8A54_10215	ENOG4105DZC	cytosine deaminase
A8A54_10225	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A8A54_10230	ENOG4108JQ9	ABC transporter
A8A54_10255	ENOG4105CJW	magnesium transporter
A8A54_10260	ENOG4105C2C	drug resistance transporter, Bcr CflA
A8A54_10265	ENOG4105DGW	oligopeptidase A
A8A54_10300	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A8A54_10315	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A8A54_10320	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A8A54_10325	ENOG4105K56	Transcriptional regulator
A8A54_10330	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A8A54_10335	ENOG4108JQ1	Dehydrogenase
A8A54_10350	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A8A54_10370	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A8A54_10375	ENOG4105K63	Thioredoxin
A8A54_10390	ENOG4105TVJ	transport system, permease
A8A54_10395	ENOG4105DQ5	transport system permease protein
A8A54_10400	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
A8A54_10405	ENOG4105E0A	ABC, transporter
A8A54_10415	ENOG4107RBR	Receptor
A8A54_10425	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A8A54_10430	ENOG4108IYU	L-aspartate oxidase
A8A54_10435	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A8A54_10465	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
A8A54_10470	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A8A54_10475	ENOG4107HP6	Transcriptional regulator
A8A54_10480	ENOG4107ZQV	short-chain dehydrogenase reductase
A8A54_10490	ENOG4105E89	ABC transporter
A8A54_10505	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
A8A54_10510	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
A8A54_10515	ENOG4107FW0	short-chain dehydrogenase reductase
A8A54_10520	ENOG4105C0A	alcohol dehydrogenase
A8A54_10550	ENOG4108IJ9	(ABC) transporter
A8A54_10555	ENOG4105BZ7	extracellular solute-binding protein family 1
A8A54_10560	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A8A54_10575	ENOG4105E2D	ec 3.2.1.52
A8A54_10585	ENOG4106N3A	copper homeostasis protein cutc
A8A54_10595	ENOG4105E70	isomerase
A8A54_10600	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
A8A54_10605	ENOG4105CE4	GlcNAc 6-P deacetylase
A8A54_10610	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
A8A54_10615	ENOG4105CH2	amidohydrolase
A8A54_10620	ENOG4108JEH	abc transporter atp-binding protein
A8A54_10640	ENOG4106V2I	dimethylaminohydrolase
A8A54_10655	ENOG4107QWB	Ornithine cyclodeaminase
A8A54_10670	ENOG4105E5Q	amino acid AbC transporter
A8A54_10675	ENOG4105E5Q	amino acid AbC transporter
A8A54_10690	ENOG4105CSH	Transporter
A8A54_10695	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A8A54_10700	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A8A54_10710	ENOG4105CFP	Peptidase U32
A8A54_10725	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A8A54_10730	ENOG41076YT	nitrate reductase, gamma subunit
A8A54_10735	ENOG4105R3A	Nitrate reductase
A8A54_10740	ENOG4108IUE	nitrate reductase beta subunit
A8A54_10745	ENOG4105CRU	nitrate reductase, alpha subunit
A8A54_10750	ENOG4105DQQ	Major facilitator superfamily MFS_1
A8A54_10765	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
A8A54_10775	ENOG4108VKQ	nitriC oxide reductase
A8A54_10795	ENOG41077A9	carbonic anhydrase
A8A54_10815	ENOG4105VG1	fes assembly suf system protein
A8A54_10855	ENOG4105EJC	lysr family transcriptional regulator
A8A54_10860	ENOG4105EQ0	Major Facilitator superfamily
A8A54_10865	ENOG4105F0F	Oxalate decarboxylase
A8A54_10870	ENOG4108ZXC	Two component transcriptional regulator, luxr family
A8A54_10875	ENOG4108ZXC	Two component transcriptional regulator, luxr family
A8A54_10910	ENOG4105BZU	Histidine kinase
A8A54_10920	ENOG4105DU1	integral membrane protein, terc
A8A54_10935	ENOG4105EG2	ABC transporter, permease
A8A54_10940	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
A8A54_10950	ENOG4108IJ9	(ABC) transporter
A8A54_10955	ENOG4105HEI	LysR family (Transcriptional regulator
A8A54_10970	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A8A54_10995	ENOG4108XEG	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A8A54_11030	ENOG4108M8H	domain protein
A8A54_11060	ENOG4105F4K	antigen 43
A8A54_11065	ENOG4108TEB	UPF0114 protein
A8A54_11070	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
A8A54_11075	ENOG4105C08	Histidine kinase
A8A54_11080	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
A8A54_11085	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A8A54_11090	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A8A54_11100	ENOG4105HDK	L-asparaginase
A8A54_11105	ENOG4105C85	amino acid
A8A54_11110	ENOG4108IJ0	Aspartate ammonia-lyase
A8A54_11115	ENOG41073TP	transcriptional regulator
A8A54_11120	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
A8A54_11125	ENOG4105CPU	Monooxygenase
A8A54_11130	ENOG4108PGP	mmge prpd family protein
A8A54_11135	ENOG4105CDA	abc transporter atp-binding protein
A8A54_11140	ENOG4105DRP	amino acid AbC transporter
A8A54_11155	ENOG4105DN3	alpha-2-macroglobulin domain protein
A8A54_11160	ENOG4108JQB	penicillin-binding protein 1C
A8A54_11185	ENOG4108RVA	ribokinase
A8A54_11190	ENOG4105DU0	nucleoside hydrolase
A8A54_11210	ENOG4108JQ9	ABC transporter
A8A54_11215	ENOG4107TFB	basic membrane
A8A54_11225	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_11230	ENOG4105F38	ABC transporter, permease
A8A54_11235	ENOG4105D38	putrescine abc transporter
A8A54_11260	ENOG4105DXI	Major Facilitator superfamily
A8A54_11265	ENOG41080HT	Transcriptional regulator, arsr family
A8A54_11345	ENOG4107TK4	histidinol-phosphate phosphatase
A8A54_11360	ENOG4108ZNX	Heat shock protein
A8A54_11365	ENOG4105C5W	Aldolase
A8A54_11380	ENOG4105C85	amino acid
A8A54_11390	ENOG4105CVE	Lytic murein transglycosylase
A8A54_11400	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
A8A54_11405	ENOG4108YZ9	Urea amidohydrolase subunit gamma
A8A54_11425	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
A8A54_11435	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
A8A54_11440	ENOG4106NZI	LysR family Transcriptional regulator
A8A54_11445	ENOG4105E0K	tonB-dependent siderophore receptor
A8A54_11450	ENOG4105J76	Periplasmic binding protein
A8A54_11455	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
A8A54_11465	ENOG4105CR8	Transcriptional regulator
A8A54_11475	ENOG4105CV8	reductase
A8A54_11485	ENOG4105C2X	Arabinose 5-phosphate isomerase
A8A54_11490	ENOG4105G5H	Membrane
A8A54_11495	ENOG4107QX8	SPFH domain, Band 7 family protein
A8A54_11500	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A8A54_11510	ENOG4105FE5	Homospermidine synthase
A8A54_11530	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A8A54_11535	ENOG4105EAQ	(twin-arginine translocation) pathway signal
A8A54_11540	ENOG4108UHU	Aldolase
A8A54_11550	ENOG4105C72	UPF0176 protein
A8A54_11555	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
A8A54_11560	ENOG4105E0C	molybdate abc transporter
A8A54_11565	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
A8A54_11580	ENOG4105D7X	high-affinity nickel-transporter
A8A54_11590	ENOG4105CC0	LysR family Transcriptional regulator
A8A54_11605	ENOG4108YYD	acetyltransferase
A8A54_11625	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
A8A54_11645	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
A8A54_11650	ENOG4105EE0	oxidoreductase
A8A54_11660	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A8A54_11665	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_11695	ENOG4105YA8	Transcriptional regulator
A8A54_11705	ENOG4105QDQ	
A8A54_11710	ENOG4105D00	flagellar biosynthetic protein flhB
A8A54_11715	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A8A54_11720	ENOG4105DD5	Flagellar motor switch protein
A8A54_11735	ENOG4107RD7	Flagellar Motor Protein, MotA
A8A54_11745	ENOG4105KTQ	flagellar basal-body rod protein
A8A54_11750	ENOG4108JIR	Flagellum-specific ATP synthase
A8A54_11760	ENOG4105SFI	flagellar basal-body rod protein
A8A54_11765	ENOG4108ZC9	flagellar basal-body rod protein flgc
A8A54_11770	ENOG4105X50	flagellar hook-basal body complex protein fliE
A8A54_11775	ENOG4105CGA	flagellar basal-body rod protein FlgG
A8A54_11780	ENOG4105XZC	flagellar basal body P-ring biosynthesis protein FlgA
A8A54_11785	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
A8A54_11805	ENOG4105CN7	Flagellar biosynthetic protein FliP
A8A54_11810	ENOG4107W75	Flagellin
A8A54_11825	ENOG4105ER2	Ompa motb domain protein
A8A54_11830	ENOG4108S15	chemotaxis, protein
A8A54_11870	ENOG4105KHD	Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK mRNA and promotes its degradation (By similarity)
A8A54_11875	ENOG410822I	Flagellar hook capping protein
A8A54_11880	ENOG4105VS8	Flagellar biosynthetic protein fliq
A8A54_11885	ENOG4105D7B	Flagellar biosynthesis protein flha
A8A54_11920	ENOG4105MYN	Zinc uptake regulation protein
A8A54_11925	ENOG4105FAV	ABC, transporter
A8A54_11935	ENOG4105NXV	High-affinity zinc uptake system protein
A8A54_11940	ENOG4105CKI	cobalamin synthesis protein
A8A54_11945	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
A8A54_12015	ENOG4108ZXC	Two component transcriptional regulator, luxr family
A8A54_12030	ENOG4107W7X	Aldolase
A8A54_12040	ENOG4108WYP	Transcriptional regulator
A8A54_12055	ENOG4105F38	ABC transporter, permease
A8A54_12070	ENOG4108WYP	Transcriptional regulator
A8A54_12075	ENOG4105E2X	shikimate dehydrogenase
A8A54_12080	ENOG4105C1G	acyl-Coa dehydrogenase
A8A54_12085	ENOG4105E39	Enoyl-CoA hydratase
A8A54_12090	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A8A54_12105	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
A8A54_12115	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8A54_12120	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_12130	ENOG4108JQ7	(ABC) transporter
A8A54_12135	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A8A54_12145	ENOG4105CHU	acetyl-coa acetyltransferase
A8A54_12165	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_12200	ENOG4105DKQ	ROK family
A8A54_12205	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
A8A54_12210	ENOG4105CNN	ABC, transporter
A8A54_12215	ENOG4105C2J	ABC transporter
A8A54_12220	ENOG4108RYR	transcriptional regulator AsnC family
A8A54_12225	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A8A54_12235	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A8A54_12240	ENOG4105D2N	Aldolase
A8A54_12245	ENOG4108YZG	isomerase
A8A54_12255	ENOG4105E98	transcriptional regulator DeoR family
A8A54_12270	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A8A54_12285	ENOG4105C2J	ABC transporter
A8A54_12290	ENOG4105CNN	ABC, transporter
A8A54_12295	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A8A54_12305	ENOG4105CMG	Carbohydrate kinase
A8A54_12320	ENOG4108NQD	
A8A54_12325	ENOG41089GP	Oxidoreductase domain protein
A8A54_12330	ENOG4105CNN	ABC, transporter
A8A54_12335	ENOG4105C2J	ABC transporter
A8A54_12345	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A8A54_12350	ENOG4106J7G	oxidoreductase
A8A54_12360	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
A8A54_12365	ENOG4108QBF	Transcriptional regulator
A8A54_12375	ENOG4105CK5	oxidoreductase
A8A54_12395	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A8A54_12400	ENOG4105DIQ	Transcriptional regulator
A8A54_12405	ENOG4105DC7	peptidase M24
A8A54_12410	ENOG4105CNN	ABC, transporter
A8A54_12415	ENOG4105CNN	ABC, transporter
A8A54_12420	ENOG4105C2J	ABC transporter
A8A54_12425	ENOG4105C2J	ABC transporter
A8A54_12435	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A8A54_12450	ENOG4105CSH	Transporter
A8A54_12475	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A8A54_12500	ENOG4105E5Q	amino acid AbC transporter
A8A54_12505	ENOG4105E5Q	amino acid AbC transporter
A8A54_12525	ENOG4105C6F	GntR Family Transcriptional Regulator
A8A54_12530	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A8A54_12540	ENOG4105CMG	Carbohydrate kinase
A8A54_12545	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
A8A54_12550	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A8A54_12560	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A8A54_12570	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A8A54_12585	ENOG4105KAV	tspo and mbr like protein
A8A54_12590	ENOG4108NIX	Factor ChrR
A8A54_12595	ENOG4105K6V	RNA polymerase
A8A54_12600	ENOG4105BZU	Histidine kinase
A8A54_12650	ENOG4105GAV	receptor
A8A54_12655	ENOG4108HUF	Transporter
A8A54_12660	ENOG4105DQ5	transport system permease protein
A8A54_12665	ENOG4108U1V	ABC transporter, permease
A8A54_12670	ENOG4105E0A	ABC, transporter
A8A54_12675	ENOG4105ECQ	AraC Family Transcriptional Regulator
A8A54_12680	ENOG4105EMU	Dehydrogenase
A8A54_12690	ENOG4105DHQ	Histidine kinase
A8A54_12710	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_12725	ENOG4105ETX	regulatoR
A8A54_12730	ENOG4106F60	Histidine kinase
A8A54_12755	ENOG4105CBN	LysR family transcriptional regulator
A8A54_12760	ENOG4105E98	transcriptional regulator DeoR family
A8A54_12785	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A8A54_12790	ENOG4105CQZ	Histidine kinase
A8A54_12800	ENOG4107ZYJ	bioY protein
A8A54_12805	ENOG4107QCX	Transporter
A8A54_12810	ENOG4108JJB	ABC transporter
A8A54_12815	ENOG4105CI2	imidazolone-5-propionate hydrolase
A8A54_12830	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_12840	ENOG4108JQ7	(ABC) transporter
A8A54_12855	ENOG4105DT3	PTS system, galactitol-specific IIc component
A8A54_12860	ENOG4105EPC	oxidoreductase
A8A54_12865	ENOG4107RUY	(E1 component), alpha subunit
A8A54_12870	ENOG4105CPP	Dehydrogenase, E1 component
A8A54_12890	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A8A54_12900	ENOG4105DZY	Pts system, glucitol sorbitol-specific
A8A54_12905	ENOG410787A	Pts system, glucitol sorbitol-specific
A8A54_12935	ENOG4105CNN	ABC, transporter
A8A54_12940	ENOG4108MGF	sugar kinase
A8A54_12945	ENOG4105DKT	Transcriptional regulator
A8A54_12955	ENOG4105DEF	Extracellular solute-binding protein, family 5
A8A54_12965	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A8A54_12980	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A8A54_13010	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A8A54_13015	ENOG4105NXH	GreA GreB family elongation factor
A8A54_13025	ENOG4108UXN	response regulator
A8A54_13030	ENOG4105BZU	Histidine kinase
A8A54_13035	ENOG4105W0E	50S ribosomal protein L33
A8A54_13055	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A8A54_13060	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A8A54_13070	ENOG4105C79	DNA protecting protein DprA
A8A54_13080	ENOG4105CD3	dihydroorotase
A8A54_13085	ENOG4105CXT	aspartate transcarbamylase
A8A54_13090	ENOG4105CSU	acyl-Coa dehydrogenase
A8A54_13095	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A8A54_13100	ENOG4107T8T	UPF0173 metal-dependent hydrolase
A8A54_13105	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A8A54_13130	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A8A54_13135	ENOG4108EHX	EamA-like transporter family
A8A54_13145	ENOG4105BZU	Histidine kinase
A8A54_13150	ENOG4105W6J	BA14K family
A8A54_13185	ENOG4105FF5	Membrane
A8A54_13190	ENOG4107QIV	Cytochrome c biogenesis protein
A8A54_13195	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A8A54_13205	ENOG4105CB5	ATP-dependent DNA helicase recG
A8A54_13210	ENOG4107NKQ	Flavinator of succinate dehydrogenase
A8A54_13250	ENOG4105VE1	Phosphatidylcholine synthase
A8A54_13255	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A8A54_13260	ENOG4108JQ9	ABC transporter
A8A54_13265	ENOG4105UIB	(ABC) transporter
A8A54_13300	ENOG4107ENK	receptor
A8A54_13310	ENOG4106QJH	hemin transport protein
A8A54_13315	ENOG4107R4I	Periplasmic binding protein
A8A54_13320	ENOG4105EHG	Permease protein
A8A54_13325	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A8A54_13330	ENOG4105KPV	Transcriptional regulator
A8A54_13335	ENOG4108UIN	ybak prolyl-trna synthetase associated region
A8A54_13370	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A8A54_13375	ENOG4105DJ2	Major Facilitator Superfamily
A8A54_13380	ENOG4107Y2X	deaminase
A8A54_13390	ENOG4108R4R	Iron-regulated virulence regulatory protein
A8A54_13400	ENOG4105BZ1	(ABC) transporter
A8A54_13410	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A8A54_13415	ENOG4105DRR	Transcriptional regulator, GntR family
A8A54_13440	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_13450	ENOG4108JQ7	(ABC) transporter
A8A54_13455	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A8A54_13460	ENOG4108JDX	DNA polymerase iii, epsilon subunit
A8A54_13465	ENOG4105BZU	Histidine kinase
A8A54_13490	ENOG4105DEN	Luciferase family
A8A54_13500	ENOG4105CH2	amidohydrolase
A8A54_13515	ENOG4105CDA	abc transporter atp-binding protein
A8A54_13520	ENOG4105EAB	amino acid AbC transporter
A8A54_13525	ENOG4105EAB	amino acid AbC transporter
A8A54_13545	ENOG4105CC0	LysR family Transcriptional regulator
A8A54_13560	ENOG4105CPU	Monooxygenase
A8A54_13575	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_13585	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
A8A54_13590	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
A8A54_13595	ENOG4105DEN	Luciferase family
A8A54_13610	ENOG4105CPU	Monooxygenase
A8A54_13615	ENOG4105CPU	Monooxygenase
A8A54_13620	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
A8A54_13670	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
A8A54_13695	ENOG4105JQN	Transcriptional regulator
A8A54_13720	ENOG4105ID8	Transcriptional regulator, ARAC family
A8A54_13725	ENOG4105CHJ	isochorismatase hydrolase
A8A54_13735	ENOG4105EFZ	amidohydrolase
A8A54_13755	ENOG4105DEF	Extracellular solute-binding protein, family 5
A8A54_13770	ENOG4105C3U	ABC transporter
A8A54_13775	ENOG4108JQ7	(ABC) transporter
A8A54_13805	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_13810	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8A54_13815	ENOG4107QRA	Extracellular solute-binding protein, family 5
A8A54_13825	ENOG4105ETT	transcriptional Regulator, LysR family
A8A54_13835	ENOG4105CHF	Glutathione S-transferase
A8A54_13845	ENOG4105F9F	transposase
A8A54_13850	ENOG4107QSI	ABC, transporter
A8A54_13855	ENOG4107QSI	ABC, transporter
A8A54_13860	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8A54_13865	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_13870	ENOG4108JQ5	ABC transporter
A8A54_13875	ENOG4105C3M	thioredoxin reductase
A8A54_13885	ENOG4105CF1	Alkylated DNA repair protein
A8A54_13890	ENOG4105C9F	isomerase
A8A54_13900	ENOG410804X	Transcriptional regulator
A8A54_13915	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
A8A54_13920	ENOG4105CNN	ABC, transporter
A8A54_13925	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
A8A54_13935	ENOG41079KZ	Major Facilitator Superfamily
A8A54_13960	ENOG4107QN2	dihydrolipoyl dehydrogenase
A8A54_13965	ENOG4107QSN	dihydrolipoamide acetyltransferase
A8A54_13970	ENOG4105CPP	Dehydrogenase, E1 component
A8A54_13975	ENOG4107R0V	Pyruvate dehydrogenase
A8A54_13985	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A8A54_13990	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A8A54_13995	ENOG4108JJ8	(ABC) transporter
A8A54_14000	ENOG4108JJ9	ABC, transporter
A8A54_14015	ENOG4105W4C	monovalent cation H antiporter subunit F
A8A54_14020	ENOG4105SC1	monovalent cation H antiporter subunit E
A8A54_14025	ENOG4107R4Z	monovalent cation h antiporter subunit d
A8A54_14030	ENOG4108ZE9	Monovalent cation H antiporter subunit C
A8A54_14035	ENOG4105D65	subunit l
A8A54_14050	ENOG4106R87	Extracellular solute-binding protein, family 5
A8A54_14075	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
A8A54_14095	ENOG4105CVG	Homoserine O-transsuccinylase
A8A54_14115	ENOG4105CK2	sodium dicarboxylate symporter
A8A54_14125	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A8A54_14130	ENOG4105E0A	ABC, transporter
A8A54_14135	ENOG4108WFR	AraC Family Transcriptional Regulator
A8A54_14140	ENOG4105E0K	tonB-dependent siderophore receptor
A8A54_14145	ENOG4105K78	MarR family Transcriptional regulator
A8A54_14150	ENOG4105BZ1	(ABC) transporter
A8A54_14160	ENOG4107ENK	receptor
A8A54_14175	ENOG4105C32	Amino acid ABC transporter (Permease)
A8A54_14185	ENOG4105C0Z	ABC transporter
A8A54_14190	ENOG4108IV0	ABC, transporter
A8A54_14205	ENOG4105CBG	Sulfatase
A8A54_14215	ENOG4105W8I	Transcriptional regulator
A8A54_14225	ENOG4105HEI	LysR family (Transcriptional regulator
A8A54_14235	ENOG4105CKW	Inner membrane protein yedI
A8A54_14250	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A8A54_14265	ENOG4105FTV	AraC Family Transcriptional Regulator
A8A54_14275	ENOG4105DIK	(ABC) transporter
A8A54_14280	ENOG4105CC5	ABC transporter
A8A54_14285	ENOG4105CC5	ABC transporter
A8A54_14290	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_14305	ENOG4105D38	putrescine abc transporter
A8A54_14310	ENOG4105ETE	Transcriptional regulator (LacI family
A8A54_14320	ENOG4105CPC	Aldo Keto reductase
A8A54_14325	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A8A54_14355	ENOG4105CPN	adenine deaminase
A8A54_14390	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A8A54_14395	ENOG4107YCY	Transcriptional regulator
A8A54_14400	ENOG4105CQB	FAD linked oxidase domain protein
A8A54_14415	ENOG4105C7N	Xanthine uracil vitamin C permease
A8A54_14430	ENOG4105F0I	Aminotransferase
A8A54_14460	ENOG4108UMI	ABC transporter, permease
A8A54_14465	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_14470	ENOG4105D01	(LipO)protein
A8A54_14475	ENOG4105CHM	Aminotransferase
A8A54_14485	ENOG4105D05	Receptor
A8A54_14490	ENOG4105NIV	Esterase
A8A54_14500	ENOG4105DHS	permease protein
A8A54_14505	ENOG4105CM4	permease protein
A8A54_14510	ENOG4108IPW	abc transporter atp-binding protein
A8A54_14520	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_14525	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8A54_14530	ENOG4105DEF	Extracellular solute-binding protein, family 5
A8A54_14535	ENOG4108JQ6	ABC transporter
A8A54_14550	ENOG4105EAB	amino acid AbC transporter
A8A54_14555	ENOG4105E5Q	amino acid AbC transporter
A8A54_14560	ENOG4105CDA	abc transporter atp-binding protein
A8A54_14565	ENOG4105C9X	ppx gppa phosphatase
A8A54_14570	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
A8A54_14575	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A8A54_14585	ENOG4108IJ9	(ABC) transporter
A8A54_14590	ENOG4105I1K	ABC transporter
A8A54_14595	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
A8A54_14610	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A8A54_14630	ENOG4107QKW	extracellular solute-binding protein family 1
A8A54_14635	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_14640	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A8A54_14650	ENOG4105E3B	Multicopper oxidase
A8A54_14660	ENOG4105CSH	Transporter
A8A54_14665	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A8A54_14670	ENOG4105D3R	alkyl hydroperoxide reductase
A8A54_14695	ENOG4105D7K	pfkb domain protein
A8A54_14700	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
A8A54_14710	ENOG4105DH8	myo-inositol catabolism
A8A54_14725	ENOG4107RCV	ABC transporter, permease
A8A54_14730	ENOG4105C4Y	ABC transporter
A8A54_14745	ENOG4105EW9	transcriptional regulator AsnC family
A8A54_14750	ENOG4105DEI	Mannitol dehydrogenase
A8A54_14795	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A8A54_14800	ENOG4105F27	Major Facilitator
A8A54_14825	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A8A54_14840	ENOG4107XKF	NMT1 THI5 Like Domain Protein
A8A54_14855	ENOG4108HQS	Glycine betaine
A8A54_14860	ENOG4108IJ7	Glycine betaine
A8A54_14875	ENOG4106KNT	transcriptional regulator
A8A54_14885	ENOG4105CHR	reductase
A8A54_14900	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A8A54_14915	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A8A54_14925	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A8A54_14930	ENOG4105CPQ	Dehydrogenase
A8A54_14935	ENOG4105CTX	dehydratase
A8A54_14940	ENOG41073TP	transcriptional regulator
A8A54_14945	ENOG4107QZW	Altronate oxidoreductase
A8A54_14955	ENOG4108XG2	Histidine kinase
A8A54_14960	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A8A54_14965	ENOG4105C2J	ABC transporter
A8A54_14975	ENOG4105CNN	ABC, transporter
A8A54_14985	ENOG4105E0A	ABC, transporter
A8A54_14990	ENOG4105EHG	Permease protein
A8A54_15025	ENOG4105KT7	mgtC SapB transporter
A8A54_15040	ENOG4105BZU	Histidine kinase
A8A54_15050	ENOG4105D38	putrescine abc transporter
A8A54_15055	ENOG4105F38	ABC transporter, permease
A8A54_15060	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_15065	ENOG4108HM4	ABC transporter
A8A54_15085	ENOG4105FFC	UPF0187 protein
A8A54_15100	ENOG4105CFQ	glutamine synthetase
A8A54_15105	ENOG4105CJP	fad dependent oxidoreductase
A8A54_15115	ENOG4105CUB	amino acid
A8A54_15120	ENOG4105KVH	Transcriptional regulator
A8A54_15155	ENOG4108QBF	Transcriptional regulator
A8A54_15160	ENOG4105C6X	Major Facilitator
A8A54_15165	ENOG4105EST	Metal Dependent Phosphohydrolase
A8A54_15175	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
A8A54_15180	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
A8A54_15185	ENOG4105C01	Dihydroxy-acid dehydratase
A8A54_15190	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A8A54_15205	ENOG4105II7	pyrroline-5-carboxylate reductase
A8A54_15215	ENOG4108JQ6	ABC transporter
A8A54_15220	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_15230	ENOG4105DEF	Extracellular solute-binding protein, family 5
A8A54_15250	ENOG4105DK7	lysyl-tRNA synthetase
A8A54_15265	ENOG4108RNG	Permease of the drug metabolite transporter
A8A54_15280	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A8A54_15285	ENOG4105CHU	acetyl-coa acetyltransferase
A8A54_15290	ENOG4105CSU	acyl-Coa dehydrogenase
A8A54_15295	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
A8A54_15300	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
A8A54_15310	ENOG4105DZ2	Transcriptional regulator
A8A54_15360	ENOG4107QRT	dEAD DEAH box helicase
A8A54_15370	ENOG4107T0X	DNA ligase
A8A54_15445	ENOG4105NVB	glycoside hydrolase, family 19
A8A54_15550	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A8A54_15605	ENOG4107T65	Integrase
A8A54_15630	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
A8A54_15640	ENOG4108JQ7	(ABC) transporter
A8A54_15645	ENOG4105C3U	ABC transporter
A8A54_15650	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_15655	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8A54_15660	ENOG4105DEF	Extracellular solute-binding protein, family 5
A8A54_15675	ENOG4105CHR	reductase
A8A54_15680	ENOG4105CMG	Carbohydrate kinase
A8A54_15685	ENOG4105X1V	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A8A54_15690	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
A8A54_15695	ENOG4105CPP	Dehydrogenase, E1 component
A8A54_15700	ENOG4107RUY	(E1 component), alpha subunit
A8A54_15705	ENOG4105CNN	ABC, transporter
A8A54_15710	ENOG4105C2J	ABC transporter
A8A54_15725	ENOG4105C8Y	Acetylornithine aminotransferase
A8A54_15730	ENOG4105E5Q	amino acid AbC transporter
A8A54_15740	ENOG4106PMH	Extracellular solute-binding protein family 3
A8A54_15745	ENOG4105CDA	abc transporter atp-binding protein
A8A54_15750	ENOG4105C26	Dehydrogenase
A8A54_15760	ENOG4105E98	transcriptional regulator DeoR family
A8A54_15790	ENOG4106PMH	Extracellular solute-binding protein family 3
A8A54_15795	ENOG4108JEH	abc transporter atp-binding protein
A8A54_15800	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
A8A54_15830	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A8A54_15835	ENOG4106FTQ	Taurine ABC transporter, periplasmic
A8A54_15845	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A8A54_15865	ENOG4108E94	phosphate acetyltransferase
A8A54_15890	ENOG4107R4I	Periplasmic binding protein
A8A54_15900	ENOG4105DG4	malate L-lactate dehydrogenase
A8A54_15905	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A8A54_15915	ENOG4105DC7	peptidase M24
A8A54_15925	ENOG4105C4Y	ABC transporter
A8A54_15930	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_15960	ENOG4105DSE	periplasmic solute binding protein
A8A54_15965	ENOG4105CC5	ABC transporter
A8A54_15970	ENOG4105DIK	(ABC) transporter
A8A54_15980	ENOG4107R6D	beta-lactam binding protein AmpH
A8A54_15990	ENOG4105C8Y	Acetylornithine aminotransferase
A8A54_15995	ENOG4105C26	Dehydrogenase
A8A54_16000	ENOG4108RYR	transcriptional regulator AsnC family
A8A54_16015	ENOG4105ENR	peptidase, M24
A8A54_16020	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
A8A54_16045	ENOG4107SQD	Transcriptional regulator, GntR family
A8A54_16050	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A8A54_16070	ENOG4105E39	Enoyl-CoA hydratase
A8A54_16080	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_16085	ENOG4105F38	ABC transporter, permease
A8A54_16090	ENOG4105CEY	Amp-dependent synthetase and ligase
A8A54_16105	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A8A54_16120	ENOG4107TFB	basic membrane
A8A54_16130	ENOG4105UIB	(ABC) transporter
A8A54_16140	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A8A54_16145	ENOG4105CPQ	Dehydrogenase
A8A54_16150	ENOG4105CHR	reductase
A8A54_16155	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A8A54_16160	ENOG4105C5I	Dehydrogenase
A8A54_16170	ENOG4105E5Q	amino acid AbC transporter
A8A54_16175	ENOG4105E5Q	amino acid AbC transporter
A8A54_16180	ENOG4107RP9	extracellular solute-binding protein, family 3
A8A54_16190	ENOG4105DIQ	Transcriptional regulator
A8A54_16195	ENOG4105CHR	reductase
A8A54_16200	ENOG4105DCT	glycerol dehydrogenase
A8A54_16205	ENOG4105CHR	reductase
A8A54_16210	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
A8A54_16215	ENOG4105CMG	Carbohydrate kinase
A8A54_16220	ENOG4105CNN	ABC, transporter
A8A54_16230	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A8A54_16235	ENOG4108Y83	glucose-6-phosphate isomerase
A8A54_16240	ENOG4108UHU	Aldolase
A8A54_16250	ENOG4108JQ1	Dehydrogenase
A8A54_16260	ENOG4106KNT	transcriptional regulator
A8A54_16265	ENOG4105CHR	reductase
A8A54_16270	ENOG4105CNN	ABC, transporter
A8A54_16275	ENOG4105C2J	ABC transporter
A8A54_16280	ENOG4105CNN	ABC, transporter
A8A54_16285	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A8A54_16290	ENOG4105ETE	Transcriptional regulator (LacI family
A8A54_16305	ENOG4107S4Y	M20 DapE family protein YgeY
A8A54_16310	ENOG4105CH2	amidohydrolase
A8A54_16315	ENOG4108JQ6	ABC transporter
A8A54_16345	ENOG4105CSH	Transporter
A8A54_16355	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A8A54_16360	ENOG4105ETE	Transcriptional regulator (LacI family
A8A54_16365	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_16400	ENOG4105CJP	fad dependent oxidoreductase
A8A54_16410	ENOG4105CD3	dihydroorotase
A8A54_16415	ENOG4105DEF	Extracellular solute-binding protein, family 5
A8A54_16435	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_16440	ENOG4108R85	Short chain dehydrogenase
A8A54_16460	ENOG4108JQ7	(ABC) transporter
A8A54_16485	ENOG4105DEF	Extracellular solute-binding protein, family 5
A8A54_16495	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_16510	ENOG4105CMT	Dihydroxyacetone kinase
A8A54_16515	ENOG4108UTZ	Dihydroxyacetone kinase
A8A54_16520	ENOG4105CMT	Dihydroxyacetone kinase
A8A54_16525	ENOG4108R85	Short chain dehydrogenase
A8A54_16530	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A8A54_16535	ENOG4105CNN	ABC, transporter
A8A54_16540	ENOG4105C2J	ABC transporter
A8A54_16545	ENOG4108K3A	Glutathione S-transferase
A8A54_16580	ENOG4105DR5	peptidase
A8A54_16585	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
A8A54_16600	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A8A54_16605	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A8A54_16610	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
A8A54_16615	ENOG4105CFH	Aspartokinase
A8A54_16620	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A8A54_16640	ENOG4105VW4	glutaredoxin 3
A8A54_16645	ENOG4105MJ2	Competence protein
A8A54_16660	ENOG4105M6F	mutator MutT protein
A8A54_16675	ENOG4105EIN	peptidylprolyl cis-trans isomerase
A8A54_16680	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A8A54_16705	ENOG41068KF	Universal stress protein
A8A54_16715	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A8A54_16720	ENOG4105C10	Electron transfer flavoprotein
A8A54_16725	ENOG4105BZJ	Electron transfer flavoprotein
A8A54_16730	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A8A54_16735	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A8A54_16740	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A8A54_16755	ENOG4105E1F	short-chain dehydrogenase reductase
A8A54_16765	ENOG4108IPJ	Membrane
A8A54_16770	ENOG4108UPT	UPF0178 protein
A8A54_16775	ENOG410829K	Lysine exporter protein (Lyse ygga)
A8A54_16780	ENOG4107ZT5	Thiol disulfide interchange protein
A8A54_16785	ENOG4105CH7	arginosuccinase
A8A54_16795	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A8A54_16805	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A8A54_16810	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A8A54_16850	ENOG4105F0N	pyrophosphate phospho-hydrolase
A8A54_16870	ENOG4105CAK	Cell division ATP-binding protein ftsE
A8A54_16915	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A8A54_16935	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A8A54_16940	ENOG4105T38	integral membrane protein
A8A54_16945	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A8A54_16950	ENOG4105C2W	permease
A8A54_16960	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A8A54_16970	ENOG4105C5H	ABC transporter
A8A54_16980	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
A8A54_16990	ENOG4105BZU	Histidine kinase
A8A54_16995	ENOG4105C29	acyl-CoA thioesterase
A8A54_17010	ENOG4108Z9K	Osmotically inducible protein
A8A54_17020	ENOG4105E33	succinate dehydrogenase
A8A54_17025	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
A8A54_17035	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
A8A54_17045	ENOG4105BZU	Histidine kinase
A8A54_17050	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A8A54_17060	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A8A54_17070	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A8A54_17075	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A8A54_17095	ENOG4107QN2	dihydrolipoyl dehydrogenase
A8A54_17115	ENOG4105C7S	Dehydrogenase
A8A54_17120	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A8A54_17125	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A8A54_17130	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A8A54_17140	ENOG4105D6Z	AFG1 family ATPase
A8A54_17150	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
A8A54_17155	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A8A54_17160	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A8A54_17165	ENOG4107835	probably involved in intracellular septation (By similarity)
A8A54_17170	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A8A54_17180	ENOG4105C59	p-type ATPase
A8A54_17185	ENOG4105W1Y	Transcriptional regulator
A8A54_17195	ENOG4105KDC	50s ribosomal protein l28
A8A54_17200	ENOG4105EX9	Membrane
A8A54_17205	ENOG4107GJV	short-chain dehydrogenase reductase
A8A54_17235	ENOG4108JU6	CBS domain protein
A8A54_17245	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A8A54_17260	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
A8A54_17265	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
A8A54_17270	ENOG4105VFE	sira family
A8A54_17275	ENOG4105CKI	cobalamin synthesis protein
A8A54_17280	ENOG4105DZ1	carboxypeptidase
A8A54_17285	ENOG4105CH2	amidohydrolase
A8A54_17295	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A8A54_17300	ENOG4105CHR	reductase
A8A54_17315	ENOG4105CHR	reductase
A8A54_17325	ENOG4105C26	Dehydrogenase
A8A54_17330	ENOG41060WC	Enoyl-CoA hydratase
A8A54_17335	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
A8A54_17345	ENOG4107P2S	Transcriptional regulator
A8A54_17360	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
A8A54_17380	ENOG4105C7J	ABC transporter, permease
A8A54_17400	ENOG4105FA0	parb-like partition protein
A8A54_17405	ENOG4107QJE	Chromosome Partitioning Protein
A8A54_17410	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
A8A54_17415	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A8A54_17425	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A8A54_17430	ENOG4105C7Z	Conserved Protein
A8A54_17435	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A8A54_17440	ENOG4108YXA	Membrane
A8A54_17445	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
A8A54_17465	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A8A54_17470	ENOG4107RZZ	dna polymerase iii epsilon subunit
A8A54_17475	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
A8A54_17480	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
A8A54_17490	ENOG4105CA3	membrane-bound lytic murein transglycosylase
A8A54_17515	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A8A54_17520	ENOG4108VRQ	UPF0314 protein
A8A54_17525	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A8A54_17530	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A8A54_17545	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A8A54_17550	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A8A54_17555	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
A8A54_17560	ENOG4105CS9	pantothenic acid kinase
A8A54_17565	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A8A54_17570	ENOG4109066	lysm domain bon superfamily protein
A8A54_17575	ENOG4105C7K	acetolactate synthase
A8A54_17585	ENOG4108YZN	class I peptide chain release factor
A8A54_17595	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A8A54_17600	ENOG4105EB3	Histidine kinase
A8A54_17605	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
A8A54_17610	ENOG4108EQA	pts system
A8A54_17615	ENOG41080Z8	PHOSPHOCARRIER protein
A8A54_17620	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A8A54_17625	ENOG4105I8F	Histidine kinase
A8A54_17630	ENOG4105K8N	protein family UPF0079, ATPase
A8A54_17635	ENOG4108S0S	Nucleotidyl transferase
A8A54_17645	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
A8A54_17655	ENOG4107RRN	ABC transporter substrate-binding protein
A8A54_17660	ENOG4105C3U	ABC transporter
A8A54_17665	ENOG4108JQ7	(ABC) transporter
A8A54_17670	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8A54_17675	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_17680	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
A8A54_17690	ENOG4105DRR	Transcriptional regulator, GntR family
A8A54_17695	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
A8A54_17705	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_17710	ENOG4105F38	ABC transporter, permease
A8A54_17715	ENOG4108I5D	sulfate abc transporter
A8A54_17730	ENOG4105E9Z	Nad-dependent epimerase dehydratase
A8A54_17735	ENOG4108ZKT	aldose 1-epimerase
A8A54_17745	ENOG4105JSC	dimethylmenaquinone methyltransferase
A8A54_17750	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A8A54_17760	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A8A54_17770	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A8A54_17775	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
A8A54_17795	ENOG4105DKK	Benzoate
A8A54_17815	ENOG41082BR	50S ribosomal protein L35
A8A54_17820	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A8A54_17825	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A8A54_17850	ENOG4105F27	Major Facilitator
A8A54_17865	ENOG4105CPC	Aldo Keto reductase
A8A54_17870	ENOG4105EQ2	LysR family Transcriptional regulator
A8A54_17890	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A8A54_17915	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
A8A54_17925	ENOG4105C0P	Mg chelatase subunit ChlI
A8A54_17930	ENOG4105CDU	Replicative dna helicase
A8A54_17940	ENOG4105K6T	rare lipoprotein A
A8A54_17950	ENOG4105WD1	Membrane
A8A54_17955	ENOG4105CHM	Aminotransferase
A8A54_17965	ENOG4105C8U	phosphate abc transporter
A8A54_17980	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
A8A54_17985	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A8A54_17990	ENOG4105F0V	Cell wall hydrolase
A8A54_18000	ENOG4105C88	aminopeptidase
A8A54_18010	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
A8A54_18015	ENOG41072GX	Peptidase M22 Glycoprotease
A8A54_18020	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
A8A54_18025	ENOG4108Z20	Acyl-transferase
A8A54_18030	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A8A54_18035	ENOG4105C9A	Phoh family
A8A54_18045	ENOG4108JU5	Magnesium and cobalt efflux protein
A8A54_18055	ENOG4108WRK	Transcriptional regulator
A8A54_18060	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A8A54_18065	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A8A54_18075	ENOG4105CHV	Transcription elongation factor NusA
A8A54_18085	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A8A54_18090	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A8A54_18095	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A8A54_18100	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A8A54_18105	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A8A54_18110	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
A8A54_18115	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A8A54_18125	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
A8A54_18135	ENOG4105D01	(LipO)protein
A8A54_18155	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
A8A54_18160	ENOG4107SN7	NLP P60 protein
A8A54_18170	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A8A54_18185	ENOG4105E39	Enoyl-CoA hydratase
A8A54_18190	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
A8A54_18200	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A8A54_18235	ENOG4108JQ5	ABC transporter
A8A54_18240	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
A8A54_18245	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
A8A54_18260	ENOG4105G9V	cytochrome C
A8A54_18265	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
A8A54_18275	ENOG4105E09	nadh pyrophosphatase
A8A54_18290	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A8A54_18295	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A8A54_18310	ENOG4105E2A	Dehydrogenase
A8A54_18315	ENOG4105DUM	transcriptional regulator, lysR family
A8A54_18320	ENOG4105HMI	Membrane
A8A54_18325	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A8A54_18330	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A8A54_18360	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A8A54_18365	ENOG4105C1G	acyl-Coa dehydrogenase
A8A54_18370	ENOG4107QX3	carboxylase
A8A54_18380	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
A8A54_18385	ENOG4108UKI	Enoyl-CoA hydratase
A8A54_18415	ENOG4105E2S	oxidase) subunit II
A8A54_18420	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A8A54_18425	ENOG4105CCU	oxidase (Subunit III)
A8A54_18430	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
A8A54_18440	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A8A54_18445	ENOG4107RSM	transcriptional regulator
A8A54_18485	ENOG4105BZU	Histidine kinase
A8A54_18490	ENOG4107Z5C	methylesterase
A8A54_18495	ENOG4105BZU	Histidine kinase
A8A54_18500	ENOG4105BZU	Histidine kinase
A8A54_18505	ENOG4105VDW	Csbd family
A8A54_18535	ENOG4107RTG	Major Facilitator superfamily
A8A54_18575	ENOG4107YNJ	LysR family Transcriptional regulator
A8A54_18590	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A8A54_18595	ENOG4108FUF	Transcriptional regulator, IclR family
A8A54_18605	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
A8A54_18615	ENOG4108E94	phosphate acetyltransferase
A8A54_18620	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A8A54_18625	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A8A54_18630	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A8A54_18635	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A8A54_18640	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A8A54_18660	ENOG4105R1U	AraC Family Transcriptional Regulator
A8A54_18670	ENOG4105TVJ	transport system, permease
A8A54_18675	ENOG4105DQ5	transport system permease protein
A8A54_18780	ENOG4105KVH	Transcriptional regulator
A8A54_18840	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A8A54_18845	ENOG4105CQZ	Histidine kinase
A8A54_18875	ENOG4108EHY	type IV secretion system
A8A54_18900	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A8A54_18910	ENOG4105CHR	reductase
A8A54_18915	ENOG4105CBN	LysR family transcriptional regulator
A8A54_18960	ENOG4107RP9	extracellular solute-binding protein, family 3
A8A54_18965	ENOG4105EAD	ABC transporter
A8A54_18970	ENOG4105DRP	amino acid AbC transporter
A8A54_18975	ENOG4105CDA	abc transporter atp-binding protein
A8A54_18980	ENOG4105XT2	Transcriptional regulator
A8A54_18985	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
A8A54_18990	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A8A54_19000	ENOG4105TPV	
A8A54_19005	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A8A54_19015	ENOG4108M9J	MaoC like domain protein
A8A54_19025	ENOG4105C1G	acyl-Coa dehydrogenase
A8A54_19030	ENOG4105DUM	transcriptional regulator, lysR family
A8A54_19035	ENOG4105E7W	lamb ycsf family protein
A8A54_19045	ENOG4107R7A	Allophanate hydrolase subunit 2
A8A54_19055	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A8A54_19060	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A8A54_19065	ENOG4106NZI	LysR family Transcriptional regulator
A8A54_19070	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A8A54_19080	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A8A54_19085	ENOG4105C26	Dehydrogenase
A8A54_19090	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A8A54_19100	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
A8A54_19140	ENOG4105CRW	Short chain fatty acid transporter
A8A54_19160	ENOG4105E5Q	amino acid AbC transporter
A8A54_19165	ENOG4105E5Q	amino acid AbC transporter
A8A54_19170	ENOG4106PMH	Extracellular solute-binding protein family 3
A8A54_19185	ENOG41067TZ	transcriptional regulator, MarR family
A8A54_19210	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A8A54_19215	ENOG4107TJ9	Cytochrome
A8A54_19230	ENOG4105D94	Major Facilitator Superfamily
A8A54_19270	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
A8A54_19275	ENOG4105EXG	Transcriptional regulator
A8A54_19305	ENOG4105CHR	reductase
A8A54_19310	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A8A54_19325	ENOG4105C5Q	Transcriptional regulator
A8A54_19340	ENOG4105E1F	short-chain dehydrogenase reductase
A8A54_19345	ENOG4105CHR	reductase
A8A54_19355	ENOG410642W	LysR family Transcriptional regulator
A8A54_19365	ENOG4105KVH	Transcriptional regulator
A8A54_19370	ENOG4105CPQ	Dehydrogenase
A8A54_19415	ENOG4106F59	XRE family Transcriptional regulator
A8A54_19475	ENOG4105C7B	Threonine dehydratase
A8A54_19500	ENOG4105CBP	Major Facilitator
A8A54_19505	ENOG4105EGI	Transcriptional regulator
A8A54_19510	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A8A54_19515	ENOG4105EA8	2-Nitropropane dioxygenase
A8A54_19520	ENOG41090U3	tautomerase
A8A54_19535	ENOG4105E4C	Lytic transglycosylase catalytic
A8A54_19560	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
A8A54_19590	ENOG4105CF7	AraC family transcriptional regulator
A8A54_19595	ENOG4105CHR	reductase
A8A54_19605	ENOG4108MVM	Transposase
A8A54_19615	ENOG4105CNU	cell division protein FtsK
A8A54_19620	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A8A54_19695	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A8A54_19710	ENOG4105CBN	LysR family transcriptional regulator
A8A54_19720	ENOG4105F27	Major Facilitator
A8A54_19725	ENOG4105HEI	LysR family (Transcriptional regulator
A8A54_19730	ENOG4105D64	Mechanosensitive ion channel
A8A54_19740	ENOG4105BZU	Histidine kinase
A8A54_19745	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
A8A54_19755	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A8A54_19760	ENOG4105CPC	Aldo Keto reductase
A8A54_19770	ENOG4105D5U	fad dependent oxidoreductase
A8A54_19775	ENOG4107W19	lmbE family
A8A54_19790	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A8A54_19795	ENOG4105EQQ	protein containing aminopeptidase domain
A8A54_19800	ENOG4105CMR	udp-glucose 4-epimerase
A8A54_19810	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A8A54_19815	ENOG4105CPK	Glycosyl transferase (Group 1
A8A54_19835	ENOG4105ESV	Glycosyl transferase, family 4
A8A54_19855	ENOG4105EQK	-acetyltransferase
A8A54_19860	ENOG4105DSF	transport protein
A8A54_19865	ENOG4105CI2	imidazolone-5-propionate hydrolase
A8A54_19915	ENOG4105WH1	Two component transcriptional regulator luxr family
A8A54_19925	ENOG4105CGP	Urocanate hydratase
A8A54_19930	ENOG4108RF4	Tetr family transcriptional regulator
A8A54_19935	ENOG4105CI2	imidazolone-5-propionate hydrolase
A8A54_19945	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_19955	ENOG4105F38	ABC transporter, permease
A8A54_20010	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
A8A54_20015	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
A8A54_20020	ENOG4108IJ8	ABC transporter
A8A54_20025	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
A8A54_20060	ENOG41061H0	Monooxygenase
A8A54_20065	ENOG4105C28	cystathionine
A8A54_20075	ENOG4105BZU	Histidine kinase
A8A54_20090	ENOG4105CN1	protease
A8A54_20095	ENOG4105CNN	ABC, transporter
A8A54_20100	ENOG4105C2J	ABC transporter
A8A54_20105	ENOG4105DDV	Transcriptional regulator (LacI family
A8A54_20115	ENOG4105ETE	Transcriptional regulator (LacI family
A8A54_20120	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_20160	ENOG4108I5G	Major Facilitator superfamily
A8A54_20165	ENOG4105DG4	malate L-lactate dehydrogenase
A8A54_20195	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A8A54_20205	ENOG4105EHG	Permease protein
A8A54_20210	ENOG4105E0A	ABC, transporter
A8A54_20235	ENOG4105CY2	Citrate transporter
A8A54_20245	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
A8A54_20255	ENOG4105CQM	Urea amidohydrolase subunit alpha
A8A54_20260	ENOG4105KI2	Urea amidohydrolase subunit beta
A8A54_20265	ENOG4108YZ9	Urea amidohydrolase subunit gamma
A8A54_20270	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
A8A54_20275	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
A8A54_20280	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
A8A54_20295	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A8A54_20310	ENOG4105BZU	Histidine kinase
A8A54_20315	ENOG4105CQZ	Histidine kinase
A8A54_20320	ENOG4108YIQ	Alpha beta hydrolase
A8A54_20335	ENOG4105J12	Multidrug resistance protein mdtN
A8A54_20340	ENOG4108MI0	Resistance protein
A8A54_20355	ENOG4105C26	Dehydrogenase
A8A54_20405	ENOG4105E0K	tonB-dependent siderophore receptor
A8A54_20410	ENOG4108K3Z	AraC family transcriptional regulator
A8A54_20465	ENOG41066DG	(EAL) domain protein
A8A54_20490	ENOG4108QBF	Transcriptional regulator
A8A54_20495	ENOG410633P	Hydantoin racemase
A8A54_20505	ENOG4105DRR	Transcriptional regulator, GntR family
A8A54_20510	ENOG4108JQ7	(ABC) transporter
A8A54_20515	ENOG4105C3U	ABC transporter
A8A54_20530	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_20545	ENOG4105CPN	adenine deaminase
A8A54_20555	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A8A54_20565	ENOG4107YNJ	LysR family Transcriptional regulator
A8A54_20575	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8A54_20580	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_20590	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A8A54_20610	ENOG4108ZT1	Transcriptional regulator
A8A54_20615	ENOG4105DJ2	Major Facilitator Superfamily
A8A54_20620	ENOG4105C5I	Dehydrogenase
A8A54_20625	ENOG4108PZW	LysR family Transcriptional regulator
A8A54_20670	ENOG4105KPV	Transcriptional regulator
A8A54_20680	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A8A54_20750	ENOG4105YAJ	CopG Arc MetJ
A8A54_20790	ENOG4108YIQ	Alpha beta hydrolase
A8A54_20815	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A8A54_20835	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A8A54_20875	ENOG4108EHY	type IV secretion system
A8A54_20880	ENOG4105CMA	conjugation trbi family protein
A8A54_20890	ENOG4108V42	Type IV secretion system protein VirB8
A8A54_20955	ENOG4107QSI	ABC, transporter
A8A54_20960	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8A54_20965	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_21040	ENOG4105E80	TraG TraD family protein
A8A54_21075	ENOG4107Y7Q	pfkb domain protein
A8A54_21085	ENOG4106IQC	argininosuccinate lyase
A8A54_21335	ENOG4107HP6	Transcriptional regulator
A8A54_21345	ENOG4107QNJ	CoA-transferase subunit B
A8A54_21350	ENOG4105CHU	acetyl-coa acetyltransferase
A8A54_21355	ENOG4108PZW	LysR family Transcriptional regulator
A8A54_21360	ENOG4105MP9	class II Aldolase
A8A54_21365	ENOG4105C5I	Dehydrogenase
A8A54_21375	ENOG4105E89	ABC transporter
A8A54_21380	ENOG4105C26	Dehydrogenase
A8A54_21385	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A8A54_21390	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A8A54_21395	ENOG4105CDA	abc transporter atp-binding protein
A8A54_21400	ENOG4108HW4	amino acid AbC transporter
A8A54_21405	ENOG4105E5Q	amino acid AbC transporter
A8A54_21410	ENOG4105BZJ	Electron transfer flavoprotein
A8A54_21415	ENOG4105C10	Electron transfer flavoprotein
A8A54_21420	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A8A54_21430	ENOG4105C8Y	Acetylornithine aminotransferase
A8A54_21435	ENOG4105E7W	lamb ycsf family protein
A8A54_21445	ENOG4107R7A	Allophanate hydrolase subunit 2
A8A54_21450	ENOG4105P4J	Allophanate hydrolase, subunit 1
A8A54_21455	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A8A54_21470	ENOG4105CHM	Aminotransferase
A8A54_21475	ENOG4105JSC	dimethylmenaquinone methyltransferase
A8A54_21480	ENOG4108KUU	Inner membrane metabolite transport protein ydjE
A8A54_21490	ENOG4108JQ1	Dehydrogenase
A8A54_21505	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A8A54_21515	ENOG4105BZU	Histidine kinase
A8A54_21520	ENOG4108ZXC	Two component transcriptional regulator, luxr family
A8A54_21550	ENOG4105D64	Mechanosensitive ion channel
A8A54_21610	ENOG4105CNM	Receptor
A8A54_21620	ENOG4105Q26	Siderophore-interacting protein
A8A54_21625	ENOG4105DQ5	transport system permease protein
A8A54_21630	ENOG4105TVJ	transport system, permease
A8A54_21665	ENOG4107QPB	Beta-lactamase domain protein
A8A54_21670	ENOG41080HT	Transcriptional regulator, arsr family
A8A54_21690	ENOG4105EXU	Membrane
A8A54_21710	ENOG4105BZU	Histidine kinase
A8A54_21730	ENOG4105I1J	Autotransporter
A8A54_21770	ENOG4105BZU	Histidine kinase
A8A54_21775	ENOG4108C33	Resolvase
A8A54_21785	ENOG4105BZU	Histidine kinase
A8A54_21795	ENOG4105PS1	invasion associated locus B
A8A54_21820	ENOG4107RHR	regulatoR
A8A54_21830	ENOG4105EG2	ABC transporter, permease
A8A54_21845	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A8A54_21850	ENOG4105EAM	Na Pi-cotransporter
A8A54_21870	ENOG4105CSV	Glutaminase
A8A54_21875	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A8A54_21880	ENOG4108BI7	Toxic component of a toxin-antitoxin (TA) module. A
A8A54_21885	ENOG4106CSM	Rv0623-like transcription factor
A8A54_21920	ENOG4105E0K	tonB-dependent siderophore receptor
A8A54_21925	ENOG4105J76	Periplasmic binding protein
A8A54_21930	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
A8A54_21935	ENOG4105E0A	ABC, transporter
A8A54_21960	ENOG410903D	sensor protein
A8A54_21980	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A8A54_21985	ENOG4105DEF	Extracellular solute-binding protein, family 5
A8A54_21990	ENOG4108W5M	transcriptional regulator
A8A54_21995	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A8A54_22000	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
A8A54_22010	ENOG4105C32	Amino acid ABC transporter (Permease)
A8A54_22025	ENOG4108IV0	ABC, transporter
A8A54_22030	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
A8A54_22055	ENOG4105C0B	DNA polymerase III (alpha subunit)
A8A54_22060	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
A8A54_22075	ENOG4105DQE	DNA ligase
A8A54_22090	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A8A54_22105	ENOG4108Z0Z	intracellular protease Pfpi family
A8A54_22150	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A8A54_22155	ENOG4108YXU	transcriptional regulator AsnC family
A8A54_22160	ENOG4105DCF	alanine dehydrogenase
A8A54_22165	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A8A54_22180	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
A8A54_22190	ENOG4105DKK	Benzoate
A8A54_22200	ENOG4105E2S	oxidase) subunit II
A8A54_22205	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A8A54_22210	ENOG4105CCU	oxidase (Subunit III)
A8A54_22215	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
A8A54_22245	ENOG4105CGK	Exodeoxyribonuclease III
A8A54_22285	ENOG4107S5I	aldo keto reductase
A8A54_22290	ENOG410642W	LysR family Transcriptional regulator
A8A54_22310	ENOG4105CIF	Ornithine Cyclodeaminase
A8A54_22325	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A8A54_22330	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
A8A54_22335	ENOG4105F38	ABC transporter, permease
A8A54_22340	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_22365	ENOG4105DWV	Homoserine O-trans-acetylase
A8A54_22375	ENOG4105JQN	Transcriptional regulator
A8A54_22440	ENOG4105DSF	transport protein
A8A54_22445	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
A8A54_22510	ENOG4108VX5	3-methyladenine DNA glycosylase
A8A54_22535	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A8A54_22640	ENOG4105FDF	Could be involved in DNA repair (By similarity)
A8A54_22660	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A8A54_22675	ENOG4107QIJ	Aconitate hydratase 2
A8A54_22695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_22705	ENOG4105CK5	oxidoreductase
A8A54_22735	ENOG4105VDT	-acetyltransferase
A8A54_22745	ENOG4108QIF	Phosphoesterase, PA-phosphatase related
A8A54_22750	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A8A54_22755	ENOG4105BZU	Histidine kinase
A8A54_22760	ENOG4105CF7	AraC family transcriptional regulator
A8A54_22765	ENOG4105DQ4	alcohol dehydrogenase
A8A54_22770	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
A8A54_22775	ENOG4107UEK	pfkb domain protein
A8A54_22780	ENOG4105CNN	ABC, transporter
A8A54_22800	ENOG4105ETE	Transcriptional regulator (LacI family
A8A54_22820	ENOG4108IJ9	(ABC) transporter
A8A54_22825	ENOG4105CHR	reductase
A8A54_22830	ENOG4105CPQ	Dehydrogenase
A8A54_22840	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A8A54_22845	ENOG4105BZU	Histidine kinase
A8A54_22850	ENOG4108K8U	Glycerol operon regulatory protein
A8A54_22860	ENOG4105DRP	amino acid AbC transporter
A8A54_22865	ENOG4105CDA	abc transporter atp-binding protein
A8A54_22870	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A8A54_22880	ENOG4105CQB	FAD linked oxidase domain protein
A8A54_22915	ENOG4105E5Q	amino acid AbC transporter
A8A54_22920	ENOG4105E5Q	amino acid AbC transporter
A8A54_22935	ENOG4105ETE	Transcriptional regulator (LacI family
A8A54_22945	ENOG4105XN3	extracellular solute-binding protein family 1
A8A54_22950	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
A8A54_22955	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A8A54_22965	ENOG4108KPW	sugar kinase
A8A54_22970	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
A8A54_22975	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A8A54_23035	ENOG4108IV0	ABC, transporter
A8A54_23040	ENOG4105C0Z	ABC transporter
A8A54_23045	ENOG4105DWV	Homoserine O-trans-acetylase
A8A54_23050	ENOG4105CMJ	mandelate racemase muconate lactonizing
A8A54_23060	ENOG4105CAF	HipA N-terminal domain protein
A8A54_23090	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8A54_23095	ENOG4108JQ6	ABC transporter
A8A54_23100	ENOG4105CJP	fad dependent oxidoreductase
A8A54_23110	ENOG4107R84	Peptidase dimerisation domain
A8A54_23130	ENOG4105F9F	transposase
A8A54_23140	ENOG4105N2W	Transcriptional regulator
A8A54_23150	ENOG4107VUR	extracellular solute-binding protein
A8A54_23180	ENOG4108JQ1	Dehydrogenase
A8A54_23185	ENOG4107W7X	Aldolase
A8A54_23195	ENOG4107S5T	Carbohydrate kinase
A8A54_23220	ENOG4105D2K	citrate carrier protein
A8A54_23230	ENOG41080HT	Transcriptional regulator, arsr family
A8A54_23245	ENOG4105TVJ	transport system, permease
A8A54_23250	ENOG4105E0A	ABC, transporter
A8A54_23255	ENOG4107R5B	glutamine synthetase
A8A54_23300	ENOG4105D6J	arsenicaL-resistance protein
A8A54_23310	ENOG4105CAU	Arsenical resistance protein, ArsH
A8A54_23335	ENOG4108Z86	Glutamine amidotransferase
A8A54_23355	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A8A54_23385	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
A8A54_23390	ENOG4105FBA	Phospholipase Carboxylesterase
A8A54_23400	ENOG4107SFI	Major Facilitator superfamily
A8A54_23415	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A8A54_23420	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
A8A54_23435	ENOG4108KEZ	Dehydrogenase
A8A54_23440	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
A8A54_23445	ENOG4105FB2	class II Aldolase
A8A54_23450	ENOG4105G63	Type III effector Hrp-dependent
A8A54_23460	ENOG4105EXW	epimerase dehydratase
A8A54_23465	ENOG4105FDP	GntR family transcriptional regulator