locus-tag	class	description
I927_00005	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
I927_00025	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
I927_00030	ENOG4105ESV	Glycosyl transferase, family 4
I927_00040	ENOG4105DWU	Membrane
I927_00045	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
I927_00050	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
I927_00055	ENOG4105D0M	Protease HtpX homolog
I927_00060	ENOG4108BPE	-transporting atpase
I927_00065	ENOG4105DA5	(ABC) transporter
I927_00070	ENOG4105E3A	(ABC) transporter
I927_00090	ENOG4105EWT	decarboxylase family
I927_00095	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
I927_00100	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
I927_00105	ENOG4105WP7	tRNA pseudouridine synthase C
I927_00110	ENOG4105DR9	pseudouridine synthase
I927_00115	ENOG4105X5C	UPF0181 protein
I927_00120	ENOG4105VEQ	Cold shock protein
I927_00125	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
I927_00140	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
I927_00145	ENOG4108Z66	YbaK ebsC protein
I927_00150	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
I927_00195	ENOG4105D5K	Hemolysin activator protein
I927_00200	ENOG4105CKT	filamentous hemagglutinin
I927_00200	ENOG4105CKT	filamentous hemagglutinin
I927_00265	ENOG41080C8	DUF218 domain
I927_00270	ENOG4108MY6	biosynthesis protein
I927_00275	ENOG4105P7J	Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide
I927_00280	ENOG41068D6	Glycosyltransferase
I927_00290	ENOG4108RJ9	Glycosyl transferase, family 2
I927_00295	ENOG4108RYC	glycosyltransferase
I927_00300	ENOG4105CVE	Lytic murein transglycosylase
I927_00305	ENOG4105C7N	Xanthine uracil vitamin C permease
I927_00310	ENOG41090EX	DsrE family
I927_00315	ENOG4107QKA	exodeoxyribonuclease V beta
I927_00320	ENOG4107QYX	exodeoxyribonuclease v alpha
I927_00325	ENOG4105E9S	glutaredoxin 2
I927_00330	ENOG4105KWI	UPF0339 protein
I927_00335	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
I927_00340	ENOG4108UJD	30S ribosomal protein S9
I927_00345	ENOG4107MKT	Stringent starvation protein a
I927_00350	ENOG4105KB2	stringent starvation protein b
I927_00355	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
I927_00360	ENOG4105C2X	Arabinose 5-phosphate isomerase
I927_00370	ENOG4106N3A	copper homeostasis protein cutc
I927_00375	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
I927_00380	ENOG4105CX6	glutaminyL-tRNA synthetase
I927_00385	ENOG4105BZG	amino acid carrier protein
I927_00395	ENOG4108QD6	
I927_00400	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
I927_00405	ENOG4105CTB	Polyprenyl synthetase
I927_00410	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
I927_00415	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
I927_00420	ENOG4105XW2	UPF0263 protein
I927_00425	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
I927_00430	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
I927_00435	ENOG4108ZZ3	UPF0260 protein
I927_00440	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
I927_00445	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
I927_00450	ENOG4108ESZ	Glycogen debranching enzyme
I927_00455	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
I927_00460	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
I927_00465	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
I927_00470	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
I927_00475	ENOG4105ETE	Transcriptional regulator (LacI family
I927_00480	ENOG4105ECP	epimerase
I927_00485	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
I927_00490	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
I927_00495	ENOG4105C75	arginyL-tRNA synthetase
I927_00500	ENOG4105NBI	YecM protein
I927_00510	ENOG4108XTF	Outer Membrane Lipoprotein
I927_00515	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
I927_00520	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
I927_00525	ENOG41063JG	Transcriptional regulator
I927_00540	ENOG4105C5I	Dehydrogenase
I927_00545	ENOG4105D60	lipoprotein releasing system transmembrane protein
I927_00550	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
I927_00555	ENOG4105D60	lipoprotein releasing system transmembrane protein
I927_00560	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
I927_00565	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
I927_00570	ENOG4105DZC	cytosine deaminase
I927_00575	ENOG4105CM2	brancheD-chain amino acid aminotransferase
I927_00580	ENOG4105ETT	transcriptional Regulator, LysR family
I927_00585	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
I927_00590	ENOG4105ED9	Protein of unknown function (DUF455)
I927_00595	ENOG4105C29	acyl-CoA thioesterase
I927_00600	ENOG4108JJ8	(ABC) transporter
I927_00605	ENOG4108JJ9	ABC, transporter
I927_00610	ENOG4105C3M	thioredoxin reductase
I927_00615	ENOG4107QR8	Thioredoxin
I927_00620	ENOG41077A9	carbonic anhydrase
I927_00625	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
I927_00630	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
I927_00635	ENOG4105EMU	Dehydrogenase
I927_00640	ENOG4105DK0	Indole-3-glycerol phosphate synthase
I927_00645	ENOG4108I0Q	anthranilate phosphoribosyltransferase
I927_00655	ENOG4105DDQ	anthranilate synthase
I927_00660	ENOG4105CRQ	synthase (Component I)
I927_00665	ENOG4105ERU	peptidase
I927_00675	ENOG4105FGM	Fructosamine kinase
I927_00680	ENOG4105CK7	Sodium proline symporter
I927_00700	ENOG4105DEF	Extracellular solute-binding protein, family 5
I927_00705	ENOG4105C22	threonyL-tRNA synthetase
I927_00720	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
I927_00725	ENOG41082NX	50s ribosomal protein l35
I927_00730	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
I927_00740	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
I927_00745	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
I927_00750	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
I927_00755	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
I927_00760	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
I927_00770	ENOG4108TZV	Membrane
I927_00775	ENOG4105CJB	Exodeoxyribonuclease I
I927_00780	ENOG4105NE1	Conserved Protein
I927_00785	ENOG41076KX	Protein of unknown function (DUF1469)
I927_00805	ENOG4105DB7	PHP domain protein
I927_00810	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
I927_00815	ENOG4105CD8	aminopeptidase N
I927_00820	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
I927_00825	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
I927_00830	ENOG4105CGF	Aromatic amino acid aminotransferase
I927_00835	ENOG4108ZAF	Molybdopterin
I927_00840	ENOG4105M00	molybdopterin converting factor, subunit 1
I927_00845	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
I927_00850	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
I927_00855	ENOG4105CHW	UPF0052 protein
I927_00860	ENOG4108QBX	(LipO)protein
I927_00865	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
I927_00870	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
I927_00880	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
I927_00890	ENOG4108W1A	pseudouridine synthase
I927_00895	ENOG4105CVJ	phosphoglycerate mutase
I927_00900	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
I927_00905	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
I927_00910	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
I927_00920	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
I927_00925	ENOG4108VD1	dedA family
I927_00930	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
I927_00935	ENOG4105DAG	ROK family
I927_00940	ENOG4105C5S	asparaginyl-tRNA synthetase
I927_00945	ENOG4108JQB	penicillin-binding protein 1C
I927_00950	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
I927_00955	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
I927_00960	ENOG41082RQ	UPF0102 protein
I927_00965	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
I927_00970	ENOG4105W4M	Transport-associated protein
I927_00975	ENOG4108R6K	riboflavin synthase, subunit alpha
I927_00980	ENOG4107QI1	Mate efflux family protein
I927_00985	ENOG4105D9R	oxidoreductase
I927_00990	ENOG4105CA9	Pyruvate kinase
I927_00995	ENOG4105DFP	Integrase
I927_01030	ENOG4106YSC	
I927_01060	ENOG4105CAR	Terminase, large subunit
I927_01115	ENOG4105VEQ	Cold shock protein
I927_01130	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
I927_01135	ENOG4105DN3	alpha-2-macroglobulin domain protein
I927_01140	ENOG4107R11	Transcriptional regulator
I927_01145	ENOG4105FE9	pseudouridine synthase
I927_01150	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
I927_01165	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
I927_01170	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
I927_01175	ENOG41090A1	ferritin
I927_01180	ENOG41090A1	ferritin
I927_01190	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
I927_01195	ENOG4105Q9Y	Universal stress protein
I927_01205	ENOG4105D07	Signal peptide peptidase, SppA
I927_01210	ENOG41069NU	Nitroreductase
I927_01220	ENOG4105XTM	Inherit from NOG: Mn2 dependent serine threonine protein kinase
I927_01230	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
I927_01235	ENOG4105EYK	Phosphatidylglycerophosphatase B
I927_01240	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
I927_01245	ENOG4107TSG	Extracellular solute-binding protein, family 5
I927_01250	ENOG4105WD1	Membrane
I927_01255	ENOG4105DGW	oligopeptidase A
I927_01260	ENOG4105K3M	)-transporter
I927_01270	ENOG4105E2R	ROK family
I927_01275	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
I927_01280	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
I927_01285	ENOG4105D1A	Methyltransferase
I927_01290	ENOG4105DDY	UPF0142 protein ycaO
I927_01295	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
I927_01305	ENOG4105GXY	Family of unknown function (DUF695) 
I927_01310	ENOG4105CGK	Exodeoxyribonuclease III
I927_01315	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
I927_01320	ENOG4105EUJ	GTP cyclohydrolase i
I927_01330	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
I927_01335	ENOG4105D06	uba thif-type nad fad binding protein
I927_01340	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
I927_01345	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
I927_01350	ENOG4105E96	Colicin v production protein
I927_01355	ENOG4105PQ6	UPF0208 membrane protein
I927_01360	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
I927_01365	ENOG4108DNC	Involved in acetate metabolism (By similarity)
I927_01370	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
I927_01375	ENOG4105CEY	Amp-dependent synthetase and ligase
I927_01380	ENOG4105R8X	Outer membrane lipoprotein Slp
I927_01385	ENOG41072GX	Peptidase M22 Glycoprotease
I927_01390	ENOG4105DVT	helicase
I927_01395	ENOG4105DSB	aldose 1-epimerase
I927_01405	ENOG4105HBR	Rna-binding protein
I927_01415	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
I927_01420	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
I927_01435	ENOG4105C8J	)-transporter
I927_01445	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
I927_01450	ENOG4105XPH	Ferredoxin
I927_01455	ENOG4105DB1	molybdopterin oxidoreductase
I927_01460	ENOG4106WHD	Tetrathionate reductase
I927_01465	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
I927_01470	ENOG4106AFQ	Histidine kinase
I927_01475	ENOG4108ZXC	Two component transcriptional regulator, luxr family
I927_01480	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
I927_01485	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
I927_01490	ENOG4108ZAI	phosphatidylglycerophosphatase a
I927_01495	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
I927_01500	ENOG4107YIM	Involved in the transcription termination process (By similarity)
I927_01505	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
I927_01510	ENOG4105E0U	tyrosine-specific transport protein
I927_01515	ENOG4108RCM	Nitroreductase
I927_01520	ENOG4105C0H	protease
I927_01525	ENOG4106J39	exported protein
I927_01530	ENOG4105CFG	Acts as a chaperone (By similarity)
I927_01550	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
I927_01560	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
I927_01565	ENOG4105E0C	molybdate abc transporter
I927_01570	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
I927_01575	ENOG4105UGU	tonB-dependent Receptor
I927_01580	ENOG4105F4R	Transcriptional regulator mode
I927_01585	ENOG4105DK2	UPF0207 protein
I927_01590	ENOG4105C0H	protease
I927_01595	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
I927_01600	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
I927_01610	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
I927_01615	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
I927_01620	ENOG410695F	Crispr-associated protein, Csm1 family
I927_01630	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
I927_01675	ENOG41063ZP	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
I927_01680	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
I927_01685	ENOG4107EP5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
I927_01690	ENOG4105PW4	Sugar fermentation stimulation protein homolog
I927_01695	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
I927_01705	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
I927_01710	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
I927_01720	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
I927_01725	ENOG4105CHV	Transcription elongation factor NusA
I927_01730	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
I927_01735	ENOG4105DW5	Transcriptional regulator
I927_01770	ENOG4105CQ7	ATP-dependent helicase
I927_01775	ENOG4105M08	Membrane
I927_01785	ENOG41084CK	capsule polysaccharide
I927_01810	ENOG4105K64	Glycosyl transferase, family 2
I927_01835	ENOG4105M2J	Glutaredoxin
I927_01840	ENOG4105HA9	of methanol dehydrogenase type
I927_01850	ENOG4108V0P	LemA family
I927_01855	ENOG4105W44	ompa motb domain protein
I927_01860	ENOG4105CQB	FAD linked oxidase domain protein
I927_01865	ENOG4105KA0	thioesterase Superfamily protein
I927_01870	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
I927_01875	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
I927_01880	ENOG4105DIQ	Transcriptional regulator
I927_01885	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
I927_01890	ENOG4105C6Z	Gluconate
I927_01895	ENOG4105C28	cystathionine
I927_01900	ENOG4105D3R	alkyl hydroperoxide reductase
I927_01905	ENOG4108ZJT	translation initiation factor, Sui1
I927_01910	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
I927_01915	ENOG4105CFV	Tetratricopeptide repeat protein
I927_01920	ENOG4105Q4A	inner membrane protein yciS
I927_01925	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
I927_01930	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
I927_01935	ENOG4105CAT	Cytidine monophosphate kinase
I927_01940	ENOG4105PE1	Receptor
I927_01945	ENOG4107RAN	Peptidase, M16
I927_01955	ENOG4105CXN	decarboxylase
I927_01960	ENOG4105D5Q	Arginine ornithine antiporter
I927_01965	ENOG4105DBV	ornithine carbamoyltransferase
I927_01970	ENOG4108MJ5	VirK protein
I927_01975	ENOG4105E0U	tyrosine-specific transport protein
I927_01980	ENOG4105C0F	tryptophanase EC 4.1.99.1
I927_01990	ENOG4105CDH	Citrulline--aspartate ligase
I927_01995	ENOG4108535	NAD dependent epimerase/dehydratase family
I927_02000	ENOG4105C8V	SAICAR synthetase
I927_02005	ENOG4108I6E	Sulfatase
I927_02010	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
I927_02015	ENOG4108RMU	ferritin dps family protein
I927_02020	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
I927_02030	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
I927_02040	ENOG4105MYG	DNA polymerase iii, chi subunit
I927_02045	ENOG4105C9Q	fumarate hydratase class II
I927_02060	ENOG4105D0Y	UPF0227 protein
I927_02065	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
I927_02070	ENOG41090BQ	Glutaredoxin
I927_02075	ENOG4107QZM	n-acetylglutamate synthase
I927_02080	ENOG4105EIP	mannose-6-phosphate isomerase
I927_02085	ENOG4108NK4	UPF0266 membrane protein
I927_02090	ENOG4105F3R	pts system mannose fructose sorbose family iid
I927_02095	ENOG4105ETZ	PTS System
I927_02100	ENOG4108EQA	pts system
I927_02105	ENOG4107RGD	Major Facilitator superfamily
I927_02110	ENOG41090HJ	UPF0265 protein
I927_02115	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
I927_02120	ENOG4105CIH	Imidazole acetol-phosphate transaminase
I927_02125	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
I927_02130	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
I927_02135	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
I927_02210	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
I927_02215	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
I927_02220	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
I927_02225	ENOG41085JB	UPF0434 protein
I927_02230	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
I927_02235	ENOG4105BZ1	(ABC) transporter
I927_02240	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
I927_02245	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I927_02250	ENOG4105DJ0	Poly(A) Polymerase
I927_02255	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
I927_02260	ENOG4105DWV	Homoserine O-trans-acetylase
I927_02265	ENOG4107GZ4	SanA protein
I927_02270	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
I927_02275	ENOG4108ZP8	Acetolactate synthase small subunit
I927_02280	ENOG4105C7K	acetolactate synthase
I927_02285	ENOG4107S6Z	Na H antiporter
I927_02290	ENOG4108SAU	DNA-binding protein H-ns
I927_02295	ENOG4105CIY	formyltetrahydrofolate deformylase
I927_02300	ENOG4105CE4	GlcNAc 6-P deacetylase
I927_02305	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
I927_02310	ENOG4105CI1	PTS System
I927_02315	ENOG4105C5H	ABC transporter
I927_02320	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
I927_02325	ENOG41067MG	lrgb family
I927_02330	ENOG4105VAW	lrga family
I927_02335	ENOG4105KK6	nuclease
I927_02340	ENOG4105C9B	Cysteine desulfurase
I927_02345	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
I927_02350	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
I927_02355	ENOG4105D1S	lipid A biosynthesis
I927_02360	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
I927_02365	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
I927_02375	ENOG4107QX8	SPFH domain, Band 7 family protein
I927_02380	ENOG4105DKW	ABC transporter
I927_02395	ENOG4107QN2	dihydrolipoyl dehydrogenase
I927_02400	ENOG4107QSN	dihydrolipoamide acetyltransferase
I927_02405	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
I927_02410	ENOG4105C5Y	PTS System
I927_02415	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
I927_02420	ENOG4105KZ7	phosphocarrier protein hpr
I927_02425	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
I927_02430	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
I927_02435	ENOG4105K8N	protein family UPF0079, ATPase
I927_02440	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
I927_02445	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
I927_02450	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
I927_02455	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
I927_02460	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
I927_02465	ENOG4108JU8	Transcriptional regulator
I927_02470	ENOG4106K28	UPF0283 membrane protein
I927_02475	ENOG4105CM6	amino acid regulated cytosolic protein
I927_02480	ENOG4108EVY	peptide transport periplasmic protein
I927_02490	ENOG4108EU3	peptide transport system, permease
I927_02495	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
I927_02505	ENOG4105CHR	reductase
I927_02515	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
I927_02520	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
I927_02525	ENOG4106QI4	
I927_02530	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
I927_02535	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
I927_02545	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
I927_02550	ENOG4107ARF	
I927_02555	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
I927_02560	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
I927_02570	ENOG4105C7N	Xanthine uracil vitamin C permease
I927_02575	ENOG4105CMR	udp-glucose 4-epimerase
I927_02580	ENOG4105EYM	Major Facilitator superfamily
I927_02585	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
I927_02590	ENOG4107XGZ	Hydrolase
I927_02595	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
I927_02600	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
I927_02610	ENOG4105C7S	Dehydrogenase
I927_02615	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
I927_02620	ENOG4105BZN	citrate synthase
I927_02625	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
I927_02630	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
I927_02635	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
I927_02640	ENOG4105C5X	domain protein
I927_02645	ENOG4105EAQ	(twin-arginine translocation) pathway signal
I927_02650	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
I927_02665	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
I927_02670	ENOG4105H2K	paraquat-inducible protein a
I927_02675	ENOG4105DY2	Paraquat-inducible protein b
I927_02680	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
I927_02685	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
I927_02690	ENOG4105F38	ABC transporter, permease
I927_02695	ENOG4105D38	putrescine abc transporter
I927_02700	ENOG4107RUE	extracellular solute-binding protein family 1
I927_02705	ENOG4107RUE	extracellular solute-binding protein family 1
I927_02710	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
I927_02715	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
I927_02720	ENOG4105D1H	recombination factor protein RarA
I927_02725	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
I927_02730	ENOG4105CNU	cell division protein FtsK
I927_02735	ENOG4105EW9	transcriptional regulator AsnC family
I927_02745	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
I927_02750	ENOG4105I7R	Adenylate cyclase
I927_02755	ENOG4107IX6	phosphate transport regulator
I927_02760	ENOG4105CJ3	phosphate transporter
I927_02770	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
I927_02780	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
I927_02785	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
I927_02790	ENOG4105DR5	peptidase
I927_02795	ENOG4105FDK	ABC transporter
I927_02800	ENOG4105FAV	ABC, transporter
I927_02805	ENOG4108JQ7	(ABC) transporter
I927_02810	ENOG4105C3U	ABC transporter
I927_02815	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
I927_02820	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
I927_02825	ENOG4105DEF	Extracellular solute-binding protein, family 5
I927_02830	ENOG4105SYT	Methylenetetrahydrofolate reductase
I927_02840	ENOG4105CFP	Peptidase U32
I927_02845	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
I927_02865	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
I927_02870	ENOG4108KP7	hydrolase
I927_02875	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
I927_02880	ENOG4105VIE	preprotein translocase, subunit YajC
I927_02885	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
I927_02890	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
I927_02895	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
I927_02900	ENOG4105C12	Phosphoribosylglycinamide synthetase
I927_02910	ENOG4105DC1	bifunctional purine biosynthesis protein purh
I927_02915	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
I927_02920	ENOG4105NRA	50s ribosomal protein l31 type b
I927_02925	ENOG4105YK5	50S ribosomal protein L36
I927_02930	ENOG41065U4	response regulator
I927_02935	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
I927_02940	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
I927_02945	ENOG4105X1Q	TOBE domain protein
I927_02950	ENOG4105DHQ	Histidine kinase
I927_02955	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
I927_02965	ENOG4109045	doxx family
I927_02975	ENOG4105E18	UPF0276 protein
I927_02990	ENOG4108WQI	RNA Polymerase
I927_03000	ENOG4108IYH	Dna topoisomerase
I927_03005	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
I927_03010	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
I927_03015	ENOG4107QIJ	Aconitate hydratase 2
I927_03020	ENOG4105C4Y	ABC transporter
I927_03025	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
I927_03030	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
I927_03035	ENOG4105E33	succinate dehydrogenase
I927_03040	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
I927_03045	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
I927_03050	ENOG4108K5H	permease YjgP YjgQ family protein
I927_03055	ENOG4108M8S	permease YjgP YjgQ family protein
I927_03060	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
I927_03065	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
I927_03075	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
I927_03080	ENOG4105T95	Thiol disulfide interChange protein
I927_03085	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
I927_03090	ENOG4105CRK	lysyL-tRNA synthetase
I927_03100	ENOG4105F0R	Cytidylyltransferase
I927_03105	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
I927_03110	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
I927_03115	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
I927_03125	ENOG4107QNR	UPF0135 protein
I927_03130	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
I927_03135	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
I927_03140	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
I927_03145	ENOG4105VFK	BolA family
I927_03155	ENOG4105E3I	toluene tolerance
I927_03160	ENOG4107PE3	Mammalian cell entry related domain protein
I927_03165	ENOG4105CY3	ABC transporter, permease
I927_03170	ENOG4105DHJ	ABC, transporter
I927_03175	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
I927_03180	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
I927_03185	ENOG4108IUZ	ABC transporter
I927_03190	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
I927_03195	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
I927_03200	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
I927_03205	ENOG4105EZE	Cupin 4 family protein
I927_03210	ENOG4105VDB	UPF0125 protein
I927_03215	ENOG4108Z1B	Cyclase dehydrase
I927_03220	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
I927_03225	ENOG4105C3G	gtp-binding protein
I927_03230	ENOG4105D5Q	Arginine ornithine antiporter
I927_03240	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
I927_03245	ENOG4108UUE	Transcriptional regulator
I927_03250	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
I927_03260	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
I927_03265	ENOG4105C2J	ABC transporter
I927_03270	ENOG4105CNN	ABC, transporter
I927_03275	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
I927_03280	ENOG4108RVA	ribokinase
I927_03285	ENOG4105ETE	Transcriptional regulator (LacI family
I927_03290	ENOG4105CQC	Prephenate dehydratase
I927_03295	ENOG4108I6A	alcohol dehydrogenase
I927_03300	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
I927_03305	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
I927_03310	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
I927_03315	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
I927_03320	ENOG4105CPF	Cell wall formation (By similarity)
I927_03325	ENOG4105DFU	Cell wall formation (By similarity)
I927_03330	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
I927_03335	ENOG4105CNI	cell division protein FtsW
I927_03340	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
I927_03345	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
I927_03350	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
I927_03355	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
I927_03360	ENOG4105CJN	penicillin-binding protein
I927_03370	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
I927_03375	ENOG4108V6E	Cell division protein mraZ
I927_03385	ENOG4108HUF	Transporter
I927_03390	ENOG4105DQ5	transport system permease protein
I927_03395	ENOG4108IHU	transport system permease protein
I927_03400	ENOG4105E0A	ABC, transporter
I927_03410	ENOG4105DMR	ABC, transporter
I927_03415	ENOG4105GBT	ABC transporter
I927_03420	ENOG4106PMH	Extracellular solute-binding protein family 3
I927_03425	ENOG4105E5Z	arginine transporter ATP-binding subunit
I927_03430	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
I927_03435	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
I927_03440	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
I927_03445	ENOG4105N42	UPF0307 protein
I927_03450	ENOG4105EPW	hflc protein
I927_03455	ENOG4107QJR	hflk protein
I927_03460	ENOG4105W8Z	4'-phosphopantetheinyl transferase
I927_03465	ENOG4105D98	threonine synthase
I927_03470	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
I927_03475	ENOG4105CFH	Aspartokinase
I927_03480	ENOG4105DFA	alanine racemase domain protein
I927_03500	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
I927_03505	ENOG4107RZZ	dna polymerase iii epsilon subunit
I927_03510	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
I927_03520	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
I927_03525	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
I927_03530	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
I927_03540	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
I927_03545	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
I927_03550	ENOG4108UBT	opacity-associated protein
I927_03560	ENOG4105DH7	May be involved in recombination (By similarity)
I927_03565	ENOG4105II7	pyrroline-5-carboxylate reductase
I927_03570	ENOG4105D8G	Major Facilitator superfamily
I927_03575	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
I927_03580	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
I927_03585	ENOG4105BZG	amino acid carrier protein
I927_03595	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
I927_03600	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
I927_03610	ENOG4105D7Q	type ii secretion system
I927_03615	ENOG4107QHF	type ii secretion system protein e
I927_03625	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
I927_03630	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
I927_03635	ENOG4105HF0	Membrane
I927_03640	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
I927_03645	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
I927_03650	ENOG4108Z6B	deaminase
I927_03655	ENOG4105F1A	Pyruvate formate-lyase
I927_03665	ENOG4105C6N	Formate acetyltransferase
I927_03670	ENOG4105TMB	Formate nitrite transporter
I927_03675	ENOG4105K59	histidine triad (HIT) protein
I927_03685	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
I927_03690	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
I927_03695	ENOG4105CTQ	phosphohexokinase
I927_03700	ENOG41076HS	cation diffusion facilitator family transporter
I927_03710	ENOG4105D1Q	UPF0246 protein
I927_03715	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
I927_03720	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
I927_03725	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
I927_03730	ENOG4105C3F	Signal peptidase i
I927_03735	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
I927_03740	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
I927_03755	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
I927_03770	ENOG4105E4F	Isochorismate synthase
I927_03775	ENOG4105CHM	Aminotransferase
I927_03790	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
I927_03795	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
I927_03800	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
I927_03805	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
I927_03815	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
I927_03820	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
I927_03825	ENOG4105D82	Glutamate dehydrogenase
I927_03830	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
I927_03835	ENOG4105CQ0	ABC transporter
I927_03850	ENOG4105E7A	Glutamine amidotransferase
I927_03855	ENOG4105C44	Serine transporter
I927_03860	ENOG4105EJQ	L-serine dehydratase
I927_03865	ENOG4108XC3	NADH ubiquinone oxidoreductase
I927_03870	ENOG4105C0B	DNA polymerase III (alpha subunit)
I927_03875	ENOG4105CH6	catalase
I927_03880	ENOG4105CBX	hi0933 family
I927_03885	ENOG4108DMF	Cytochrome C biogenesis protein
I927_03890	ENOG4108DMF	Cytochrome C biogenesis protein
I927_03895	ENOG4107QX9	Thiol disulfide interChange protein
I927_03900	ENOG4105DA4	cytochrome c-type biogenesis protein
I927_03905	ENOG4105DVI	reductase, NrfD
I927_03910	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
I927_03915	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
I927_03920	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
I927_03930	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
I927_03935	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
I927_03940	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
I927_03945	ENOG4105C2W	permease
I927_03950	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
I927_03965	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
I927_03970	ENOG4108M1T	Cytochrome c-type biogenesis protein
I927_03985	ENOG4107QX9	Thiol disulfide interChange protein
I927_03990	ENOG4105DA4	cytochrome c-type biogenesis protein
I927_03995	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
I927_04000	ENOG4105X3C	heme exporter protein
I927_04005	ENOG41060IM	Heme exporter protein
I927_04010	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
I927_04015	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
I927_04020	ENOG4105C2C	drug resistance transporter, Bcr CflA
I927_04025	ENOG4105I08	Pseudouridine synthase
I927_04030	ENOG4105C6K	Malic enzyme
I927_04035	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
I927_04040	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
I927_04060	ENOG4105N21	Membrane
I927_04065	ENOG4105CUT	histidyl-tRNA synthetase
I927_04070	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
I927_04075	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
I927_04080	ENOG41090FY	type IV pilus biogenesis stability protein PilW
I927_04085	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
I927_04090	ENOG4105DSF	transport protein
I927_04095	ENOG4108YZA	Nitrogen regulatory protein pii
I927_04100	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
I927_04105	ENOG4108HPI	phosphatidate Cytidylyltransferase
I927_04115	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
I927_04120	ENOG4107QWE	)-transporter
I927_04125	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
I927_04130	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
I927_04135	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
I927_04140	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
I927_04145	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
I927_04155	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I927_04160	ENOG4105DZP	Membrane-associated zinc metalloprotease
I927_04165	ENOG4105KNE	Phosphatidate cytidylyltransferase
I927_04170	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
I927_04175	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
I927_04180	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
I927_04185	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
I927_04190	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
I927_04195	ENOG4105CE9	30S ribosomal protein S2
I927_04200	ENOG4105D0S	secretion protein (HlyD
I927_04205	ENOG4105CJ1	ABC, transporter
I927_04210	ENOG4105CMI	transporter
I927_04215	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
I927_04220	ENOG4105EIN	peptidylprolyl cis-trans isomerase
I927_04225	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
I927_04230	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
I927_04235	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
I927_04240	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
I927_04245	ENOG4108WZM	domain protein
I927_04250	ENOG4105CGZ	zinc metallopeptidase
I927_04255	ENOG410787A	Pts system, glucitol sorbitol-specific
I927_04260	ENOG4105DZY	Pts system, glucitol sorbitol-specific
I927_04265	ENOG4105VI0	Pts system, glucitol sorbitol-specific
I927_04270	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
I927_04275	ENOG4105J92	DNA-binding transcriptional activator GutM
I927_04280	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
I927_04285	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
I927_04290	ENOG410804X	Transcriptional regulator
I927_04295	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
I927_04300	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
I927_04305	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
I927_04310	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
I927_04315	ENOG4108ZPB	UPF0306 protein
I927_04325	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
I927_04330	ENOG4105DFF	Rod shape-determining protein mreb
I927_04335	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
I927_04340	ENOG4105C2N	RNA methyltransferase TrmH family group 3
I927_04345	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
I927_04360	ENOG4108UUM	single-stranded DNA-binding protein
I927_04385	ENOG410642W	LysR family Transcriptional regulator
I927_04415	ENOG4105W1Y	Transcriptional regulator
I927_04420	ENOG4105D6J	arsenicaL-resistance protein
I927_04425	ENOG4105D6J	arsenicaL-resistance protein
I927_04440	ENOG4107STQ	Multicopper oxidase
I927_04445	ENOG4105D6J	arsenicaL-resistance protein
I927_04495	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
I927_04505	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
I927_04510	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
I927_04520	ENOG4105DZ1	carboxypeptidase
I927_04525	ENOG4105K6T	rare lipoprotein A
I927_04530	ENOG4105CNI	cell division protein FtsW
I927_04535	ENOG4105CJN	penicillin-binding protein
I927_04540	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
I927_04545	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
I927_04550	ENOG4105C1J	atp-dependent rna helicase
I927_04555	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
I927_04565	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
I927_04570	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
I927_04575	ENOG4105CHR	reductase
I927_04580	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
I927_04585	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
I927_04590	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
I927_04595	ENOG4105VGS	50s ribosomal protein l32
I927_04600	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
I927_04605	ENOG4107QSI	ABC, transporter
I927_04610	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
I927_04615	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
I927_04620	ENOG4105C3U	ABC transporter
I927_04625	ENOG4108JQ7	(ABC) transporter
I927_04635	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
I927_04640	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
I927_04645	ENOG4105HSA	Protein of unknown function (DUF452)
I927_04650	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
I927_04655	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
I927_04660	ENOG4105DJ4	phosphatidylserine decarboxylase
I927_04665	ENOG4108V1T	peptidylprolyl cis-trans isomerase
I927_04675	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
I927_04680	ENOG4105DWK	Membrane
I927_04685	ENOG4107XM3	UPF0442 protein
I927_04690	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
I927_04695	ENOG4105C59	p-type ATPase
I927_04710	ENOG4105EX9	Membrane
I927_04715	ENOG4105E0F	Histidine kinase
I927_04720	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
I927_04725	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
I927_04730	ENOG4106V8H	Nucleoid-associated protein
I927_04735	ENOG4105YDX	UPF0352 protein
I927_04740	ENOG4105E68	Sulfatase
I927_04750	ENOG4105PAD	Hydrolase
I927_04755	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
I927_04765	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
I927_04770	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
I927_04775	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
I927_04780	ENOG4105DSJ	YicC domain protein
I927_04785	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
I927_04795	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
I927_04815	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
I927_04820	ENOG4108UJU	UPF0301 protein
I927_04825	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
I927_04830	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
I927_04835	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
I927_04840	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
I927_04845	ENOG41080IJ	Diacylglycerol kinase
I927_04850	ENOG4105PF3	O-Antigen polymerase
I927_04855	ENOG4105D2N	Aldolase
I927_04860	ENOG4105BZA	Phosphoglycerate kinase
I927_04865	ENOG41083KI	ribonuclease, T2
I927_04870	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
I927_04875	ENOG4105EIB	trna rrna methyltransferase
I927_04880	ENOG4105JIM	Phosphatidylserine synthase
I927_04885	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
I927_04890	ENOG4107QR9	Iron-sulfur cluster binding protein
I927_04895	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
I927_04900	ENOG4105DAA	L-lactate
I927_04905	ENOG4107QTF	adenylosuccinate lyase
I927_04910	ENOG41075W9	High frequency lysogenization protein HflD homolog
I927_04915	ENOG4105D7K	pfkb domain protein
I927_04925	ENOG4105WBN	Transcriptional regulator (LacI family
I927_04930	ENOG4105C5Y	PTS System
I927_04940	ENOG4105XA0	heptosyltransferase ii
I927_04945	ENOG4105D16	lipopolysaccharide heptosyltransferase i
I927_04955	ENOG4105C1J	atp-dependent rna helicase
I927_04960	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
I927_04970	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
I927_04975	ENOG4105D3G	Pseudouridine synthase
I927_04980	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
I927_04985	ENOG4105XCT	Protein of unknown function (DUF2489)
I927_04990	ENOG4105D4P	Coproporphyrinogen iii oxidase
I927_04995	ENOG4108RCM	Nitroreductase
I927_05010	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
I927_05015	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
I927_05040	ENOG4105E6M	Sulphatase-modifying factor protein
I927_05080	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
I927_05085	ENOG4105Y3E	Modulates RecA activity (By similarity)
I927_05090	ENOG410601J	HemY protein
I927_05095	ENOG4105ECF	c-methyltransferase
I927_05105	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
I927_05110	ENOG4107T0K	Adenylate cyclase
I927_05115	ENOG4105WH1	Two component transcriptional regulator luxr family
I927_05120	ENOG4105CFU	surface antigen
I927_05125	ENOG4105MA0	exported protein
I927_05130	ENOG4105C9X	ppx gppa phosphatase
I927_05135	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
I927_05145	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
I927_05150	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
I927_05155	ENOG4108WFC	UPF0438 protein yifE
I927_05160	ENOG4108Z33	Thiol disulfide Interchange Protein
I927_05170	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
I927_05180	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
I927_05185	ENOG4105DE4	1-phosphofructokinase
I927_05190	ENOG4105DM4	PTS System
I927_05195	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
I927_05200	ENOG4108J2R	molybdopterin oxidoreductase
I927_05205	ENOG4105CUW	cytochrome C-TYPE protein
I927_05215	ENOG4105C94	Transporter
I927_05220	ENOG4105Y75	tpr repeat protein
I927_05225	ENOG4105EMN	RNA polymerase sigma factor
I927_05230	ENOG41069PW	sigma-e factor negative regulatory protein
I927_05235	ENOG4105VQK	sigma E regulatory protein, MucB RseB
I927_05240	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
I927_05245	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
I927_05250	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
I927_05265	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
I927_05270	ENOG4105DU0	nucleoside hydrolase
I927_05275	ENOG4105EM7	Selenocysteine-specific translation elongation factor
I927_05280	ENOG4105N1P	Ferredoxin-type protein
I927_05285	ENOG4108NEM	leader-binding protein dmsD
I927_05290	ENOG4107KGK	dmso reductase anchor subunit
I927_05295	ENOG4105QAX	Iron-sulfur
I927_05300	ENOG4107QY8	reductase
I927_05305	ENOG4105KT7	mgtC SapB transporter
I927_05310	ENOG4105CI1	PTS System
I927_05315	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
I927_05320	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
I927_05325	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
I927_05330	ENOG4105CS9	pantothenic acid kinase
I927_05335	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
I927_05345	ENOG4105C6Z	Gluconate
I927_05350	ENOG4105EXW	epimerase dehydratase
I927_05355	ENOG4105V1F	Fermentation respiration switch protein
I927_05365	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
I927_05370	ENOG4105FB2	class II Aldolase
I927_05375	ENOG4105G63	Type III effector Hrp-dependent
I927_05380	ENOG4105ZXK	Dehydrogenase
I927_05385	ENOG4105MVE	transcriptional regulator
I927_05390	ENOG4105CIN	aminoacyl-histidine dipeptidase
I927_05395	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
I927_05400	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
I927_05405	ENOG4105CMG	Carbohydrate kinase
I927_05410	ENOG4105C93	Xylose Isomerase
I927_05420	ENOG4105DFD	Na H antiporter
I927_05425	ENOG4105DFW	ABC transporter
I927_05430	ENOG4105C2J	ABC transporter
I927_05435	ENOG4108HWW	ABC transporter
I927_05440	ENOG4105T16	Transcriptional regulator (AraC family)
I927_05460	ENOG4105DKQ	ROK family
I927_05470	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
I927_05475	ENOG4105CNN	ABC, transporter
I927_05480	ENOG4105C2J	ABC transporter
I927_05485	ENOG4105CQZ	Histidine kinase
I927_05495	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
I927_05500	ENOG4105CJP	fad dependent oxidoreductase
I927_05505	ENOG4107RUE	extracellular solute-binding protein family 1
I927_05510	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
I927_05515	ENOG4105W0Z	cytoplasmic protein
I927_05520	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
I927_05525	ENOG4108VVQ	metallophosphoesterase
I927_05530	ENOG4108ZT0	50S ribosomal protein l17
I927_05535	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
I927_05540	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
I927_05550	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
I927_05555	ENOG41067V7	50S ribosomal protein L36
I927_05560	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
I927_05565	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
I927_05570	ENOG4105VPB	50S ribosomal protein L30
I927_05575	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
I927_05580	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
I927_05585	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
I927_05590	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
I927_05595	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
I927_05600	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
I927_05605	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
I927_05610	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
I927_05615	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
I927_05620	ENOG41083MP	50s ribosomal protein l29
I927_05625	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
I927_05630	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
I927_05635	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
I927_05640	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
I927_05645	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
I927_05650	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
I927_05655	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
I927_05660	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
I927_05680	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
I927_05695	ENOG4105C0F	tryptophanase EC 4.1.99.1
I927_05700	ENOG4106AFN	Lyase and sodium transporter (By similarity)
I927_05705	ENOG4107QSA	Oxaloacetate decarboxylase
I927_05710	ENOG4105D9Q	decarboxylase (Beta subunit)
I927_05715	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
I927_05725	ENOG4105XQ6	frataxin-like protein
I927_05730	ENOG4105HDD	phospholipase
I927_05735	ENOG4105C9U	ATP-dependent DNA helicase RecQ
I927_05740	ENOG4105UGU	tonB-dependent Receptor
I927_05745	ENOG4105F9E	Shikimate 5-dehydrogenase
I927_05750	ENOG4105D7W	serine acetyltransferase
I927_05755	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
I927_05760	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
I927_05765	ENOG4107YZP	Rhodanese domain protein
I927_05770	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
I927_05775	ENOG4105D7A	ATP-binding protein
I927_05790	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
I927_05795	ENOG4105E98	transcriptional regulator DeoR family
I927_05800	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
I927_05805	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
I927_05810	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
I927_05815	ENOG4105CXY	transporter
I927_05820	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
I927_05825	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
I927_05830	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
I927_05835	ENOG41060QA	UPF0267 protein
I927_05875	ENOG4105BZM	domain protein
I927_05885	ENOG4108RRZ	Transcription elongation factor GreB
I927_05895	ENOG4106HK8	GPR1 FUN34 yaaH family protein
I927_05900	ENOG4108EKI	Dehydrogenase
I927_05905	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
I927_05910	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
I927_05915	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
I927_05925	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
I927_05935	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
I927_05940	ENOG4105HMI	Membrane
I927_05945	ENOG4105DDQ	anthranilate synthase
I927_05950	ENOG4105CRQ	synthase (Component I)
I927_05960	ENOG4105KME	endoribonuclease L-psp
I927_05975	ENOG4108QD1	Membrane
I927_05980	ENOG4108V1U	phospholipid-binding protein
I927_05985	ENOG4105KVH	Transcriptional regulator
I927_05995	ENOG4105BZ1	(ABC) transporter
I927_06000	ENOG4108JJ9	ABC, transporter
I927_06010	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
I927_06020	ENOG4106IEQ	
I927_06030	ENOG4108V62	Rhodanese domain protein
I927_06035	ENOG41080HT	Transcriptional regulator, arsr family
I927_06040	ENOG4105CBT	Fructose-1,6-bisphosphatase
I927_06045	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
I927_06050	ENOG4105QTB	Flavodoxin
I927_06055	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
I927_06060	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
I927_06070	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
I927_06075	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
I927_06080	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
I927_06085	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
I927_06090	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
I927_06095	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
I927_06100	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
I927_06105	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
I927_06110	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
I927_06115	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
I927_06120	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
I927_06125	ENOG4108RR8	protoporphyrinogen oxidase
I927_06135	ENOG4105XWI	UPF0304 protein
I927_06140	ENOG410903C	(LipO)protein
I927_06145	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
I927_06150	ENOG4105JAB	phenazine biosynthesis protein, phzf family
I927_06160	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
I927_06165	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
I927_06170	ENOG41063SB	peptidase
I927_06175	ENOG4105PXI	polysaccharide deacetylase
I927_06180	ENOG41079J1	
I927_06185	ENOG4105C0P	Mg chelatase subunit ChlI
I927_06190	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
I927_06195	ENOG4108MJ5	VirK protein
I927_06200	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
I927_06215	ENOG4106H78	methyltransferase
I927_06225	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
I927_06230	ENOG4105CAK	Cell division ATP-binding protein ftsE
I927_06235	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
I927_06240	ENOG4107UWN	reductase
I927_06245	ENOG4105EFA	4-hydroxyphenylacetate
I927_06265	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
I927_06280	ENOG4105C26	Dehydrogenase
I927_06285	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
I927_06295	ENOG4105C2C	drug resistance transporter, Bcr CflA
I927_06310	ENOG4105C26	Dehydrogenase
I927_06315	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
I927_06320	ENOG4107RK2	ADP-ribose diphosphatase NudE
I927_06325	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
I927_06330	ENOG4105VEJ	Heat shock protein
I927_06335	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
I927_06340	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
I927_06345	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
I927_06355	ENOG4108RXX	maleylacetoacetate isomerase
I927_06380	ENOG4105MJ2	Competence protein
I927_06385	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
I927_06395	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
I927_06400	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
I927_06405	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
I927_06410	ENOG4105K64	Glycosyl transferase, family 2
I927_06415	ENOG4105C1A	potassium transporter peripheral membrane
I927_06420	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
I927_06425	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
I927_06435	ENOG4108YZY	peptidylprolyl cis-trans isomerase
I927_06440	ENOG4105Z2P	Protein of unknown function (DUF465)
I927_06445	ENOG4105KJF	protein tyrosine phosphatase
I927_06455	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
I927_06460	ENOG4108I5U	Uridine phosphorylase
I927_06465	ENOG4108VVK	transcriptional Regulator, AsnC
I927_06470	ENOG4105CU9	asparagine synthetase A
I927_06480	ENOG4105C5Y	PTS System
I927_06485	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
I927_06510	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
I927_06515	ENOG4105C5H	ABC transporter
I927_06525	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
I927_06530	ENOG4105C8P	)-transporter
I927_06535	ENOG4107RZC	phospholipase d
I927_06540	ENOG4108NKP	c4-dicarboxylate transporter malic acid transport protein
I927_06550	ENOG4105D4A	Cell wall formation (By similarity)
I927_06555	ENOG4107XNU	peptidase
I927_06580	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
I927_06585	ENOG4108BGM	Quinol dehydrogenase periplasmic component
I927_06590	ENOG4105GXZ	Ferredoxin-type protein NapH
I927_06595	ENOG4105IYZ	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
I927_06600	ENOG4105CUW	cytochrome C-TYPE protein
I927_06605	ENOG4105C79	DNA protecting protein DprA
I927_06610	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
I927_06615	ENOG4108R3E	Dna-3-methyladenine glycosylase i
I927_06620	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
I927_06635	ENOG4108R99	pseudouridine synthase
I927_06640	ENOG4108HMX	isocitrate dehydrogenase (NADP)
I927_06645	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
I927_06650	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
I927_06655	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
I927_06660	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
I927_06670	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
I927_06675	ENOG4108UM1	dedA family
I927_06685	ENOG4108K5P	(LipO)protein
I927_06690	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
I927_06695	ENOG4107S2Z	UPF0761 membrane protein
I927_06700	ENOG4105K5B	UPF0225 protein
I927_06710	ENOG4105DJV	ribulose-phosphate 3-epimerase
I927_06715	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
I927_06720	ENOG4105C31	Tryptophanyl-tRNA synthetase
I927_06725	ENOG4108MVK	Receptor
I927_06735	ENOG4105C7B	Threonine dehydratase
I927_06740	ENOG4105C01	Dihydroxy-acid dehydratase
I927_06750	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
I927_06760	ENOG4105DQF	Hydrolase
I927_06775	ENOG4108EUD	Lysophospholipase
I927_06780	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
I927_06785	ENOG4105CV1	Transketolase (EC 2.2.1.1)
I927_06790	ENOG410667J	hydrolase
I927_06795	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
I927_06800	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
I927_06810	ENOG4105CMG	Carbohydrate kinase
I927_06830	ENOG4105C2J	ABC transporter
I927_06835	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
I927_06840	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
I927_06845	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
I927_06850	ENOG4108R66	Conserved Protein
I927_06855	ENOG4105DG4	malate L-lactate dehydrogenase
I927_06860	ENOG4105J4Q	Transcriptional regulator
I927_06865	ENOG4108TEB	UPF0114 protein
I927_06870	ENOG4105CSH	Transporter
I927_06875	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
I927_06880	ENOG4105DWF	phosphomethylpyrimidine kinase
I927_06885	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
I927_06890	ENOG4107Z6I	Thiamine biosynthesis protein
I927_06895	ENOG4105ETU	transcriptional activator (TenA
I927_06900	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
I927_06905	ENOG4108YI8	ABC transporter
I927_06910	ENOG4105CGY	Dna recombination protein
I927_06915	ENOG4108Z03	MAF-like protein
I927_06920	ENOG4108WI1	Dna topoisomerase
I927_06925	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
I927_06930	ENOG4105E2X	shikimate dehydrogenase
I927_06935	ENOG4107RYS	Autoinducer-2 (AI-2) kinase
I927_06940	ENOG4105DKT	Transcriptional regulator
I927_06945	ENOG4105C2J	ABC transporter
I927_06965	ENOG41061GT	Aldolase
I927_06980	ENOG4105DTR	rard protein
I927_06985	ENOG4105EMY	transcriptional regulator
I927_06990	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
I927_06995	ENOG4105DXN	mazG family
I927_07000	ENOG4108M6U	Universal stress protein A
I927_07005	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
I927_07010	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
I927_07015	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
I927_07020	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
I927_07025	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
I927_07030	ENOG4105D9N	nucleoside
I927_07035	ENOG4108VW9	Membrane
I927_07040	ENOG4105M5K	heptosyltransferase
I927_07045	ENOG4105K5M	30s ribosomal protein S16
I927_07050	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
I927_07055	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
I927_07060	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
I927_07070	ENOG4105CH2	amidohydrolase
I927_07075	ENOG4105BZ1	(ABC) transporter
I927_07080	ENOG4105DKP	glycosyl transferase, family 9
I927_07085	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
I927_07090	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
I927_07095	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
I927_07100	ENOG4106WTF	Glycosyl transferase, family 2
I927_07105	ENOG4105S10	periplasmic binding protein
I927_07110	ENOG4105EHG	Permease protein
I927_07115	ENOG4105E0A	ABC, transporter
I927_07120	ENOG4108BSC	Methyltransferase
I927_07125	ENOG4105CP7	Triose-phosphate isomerase
I927_07130	ENOG4108HYK	gCN5-related N-acetyltransferase
I927_07135	ENOG4105VZ9	UPF0235 protein
I927_07140	ENOG4108VIA	integral membrane protein
I927_07145	ENOG4107QUT	magnesium and cobalt transport protein CorA
I927_07150	ENOG41090ED	Protein with unknown function (DUF469)
I927_07155	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
I927_07160	ENOG4105CPW	cytochrome b561
I927_07165	ENOG4105CEN	a g-specific adenine glycosylase
I927_07170	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
I927_07175	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
I927_07185	ENOG4105IEY	(LipO)protein
I927_07190	ENOG4105M85	Bola protein
I927_07195	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
I927_07200	ENOG4105C2J	ABC transporter
I927_07205	ENOG4105CNN	ABC, transporter
I927_07210	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
I927_07215	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
I927_07220	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
I927_07225	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
I927_07230	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
I927_07235	ENOG4108EGU	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
I927_07240	ENOG4105CJ2	(LipO)protein
I927_07250	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
I927_07255	ENOG4105PGM	cation diffusion facilitator family transporter
I927_07260	ENOG4105CXY	transporter
I927_07265	ENOG4105BZU	Histidine kinase
I927_07270	ENOG4108KX4	response regulator
I927_07275	ENOG4105CXY	transporter
I927_07280	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
I927_07285	ENOG4107EDW	L-fucose operon activator
I927_07290	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
I927_07295	ENOG4105CMG	Carbohydrate kinase
I927_07300	ENOG4105NWF	RbsD or FucU transport
I927_07305	ENOG4107W7X	Aldolase
I927_07310	ENOG4105C2J	ABC transporter
I927_07315	ENOG4105CNN	ABC, transporter
I927_07320	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
I927_07325	ENOG4105C26	Dehydrogenase
I927_07330	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
I927_07335	ENOG4107FB0	transcriptional regulator DeoR family
I927_07340	ENOG4105EJ2	Transcriptional regulator
I927_07345	ENOG4105C5Q	Transcriptional regulator
I927_07350	ENOG4105EHV	domain protein
I927_07355	ENOG41069P5	Protein slyX homolog
I927_07360	ENOG4108V1T	peptidylprolyl cis-trans isomerase
I927_07365	ENOG4105WWK	YheO domain protein
I927_07370	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
I927_07375	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
I927_07385	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
I927_07390	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
I927_07395	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
I927_07400	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
I927_07405	ENOG4105PM1	preprotein translocase subunit SecE
I927_07410	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
I927_07415	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
I927_07420	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
I927_07425	ENOG4105BZW	Glycerate kinase
I927_07430	ENOG4105C6Z	Gluconate
I927_07435	ENOG4108VZM	50s ribosomal protein L10
I927_07440	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
I927_07445	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
I927_07450	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
I927_07455	ENOG4105E09	nadh pyrophosphatase
I927_07460	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
I927_07465	ENOG4105R2J	Conserved Protein
I927_07470	ENOG4105K70	DNA-binding protein
I927_07475	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
I927_07485	ENOG4105D01	(LipO)protein
I927_07490	ENOG4108UMI	ABC transporter, permease
I927_07495	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
I927_07500	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
I927_07505	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
I927_07510	ENOG4105D0A	hydroxylase
I927_07515	ENOG4107RAQ	aminopeptidase
I927_07520	ENOG4105E07	UPF0149 protein
I927_07525	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
I927_07530	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
I927_07535	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I927_07540	ENOG4105C34	Pseudouridine synthase
I927_07545	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
I927_07555	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
I927_07560	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
I927_07565	ENOG4105QEK	Transcriptional regulator
I927_07570	ENOG4108R66	Conserved Protein
I927_07575	ENOG4105EVU	fructokinase
I927_07580	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
I927_07600	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
I927_07615	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
I927_07620	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
I927_07630	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
I927_07635	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
I927_07650	ENOG4107ZVW	dihydroneopterin aldolase
I927_07655	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
I927_07660	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
I927_07665	ENOG4105EXN	Sulfate transport protein CysZ
I927_07670	ENOG4105C6T	cysteine synthase
I927_07675	ENOG4105D52	delta-aminolevulinic acid dehydratase
I927_07680	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
I927_07690	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
I927_07695	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
I927_07700	ENOG4105JC1	sterol-binding domain protein
I927_07710	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
I927_07715	ENOG4105C2I	pirin domain protein
I927_07720	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
I927_07725	ENOG4105E0M	Sulfatase
I927_07730	ENOG4105CBG	Sulfatase
I927_07750	ENOG4105C4X	radical SAM domain protein
I927_07755	ENOG4105C37	(CBS) domain
I927_07760	ENOG4105RX8	Protein of unknown function (DUF1523)
I927_07765	ENOG4105F8V	Hydrolase, tatD family
I927_07770	ENOG4107QRG	dna polymerase iii
I927_07775	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
I927_07780	ENOG4105HHA	aminodeoxychorismate lyase
I927_07785	ENOG4108JQ1	Dehydrogenase
I927_07790	ENOG4105E66	phosphoriboisomerase A
I927_07795	ENOG4105CSA	Coproporphyrinogen iii oxidase
I927_07800	ENOG4105K8R	UPF0145 protein
I927_07810	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
I927_07815	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
I927_07830	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
I927_07835	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
I927_07840	ENOG4105DTN	riboflavin biosynthesis protein ribF
I927_07845	ENOG4105CJR	Integral membrane protein (MviN
I927_07850	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
I927_07855	ENOG41062Z9	Membrane
I927_07860	ENOG4105EAC	phosphoserine phosphatase
I927_07865	ENOG4108VPT	UPF0234 protein
I927_07875	ENOG4105DFP	Integrase
I927_07925	ENOG4105DFP	Integrase
I927_07945	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
I927_07960	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
I927_07965	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
I927_07970	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
I927_07975	ENOG4105VCC	30S ribosomal protein S21
I927_07990	ENOG4107104	thymidine kinase
I927_07995	ENOG4105DC8	reductase
I927_08000	ENOG4105D6S	protein involved in catabolism of external DNA
I927_08005	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
I927_08010	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
I927_08015	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
I927_08020	ENOG4108JQC	penicillin-binding protein 1A
I927_08045	ENOG4105E4G	Type IV pilus
I927_08050	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
I927_08055	ENOG4105D49	3-dehydroquinate synthase
I927_08060	ENOG4105DFE	Dna adenine methylase
I927_08085	ENOG4105M6F	mutator MutT protein
I927_08095	ENOG4105DJF	DNA polymerase III, delta' subunit
I927_08105	ENOG4105C8T	Leucyl-tRNA synthetase
I927_08115	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
I927_08120	ENOG410681U	heavy metal transport detoxification protein
I927_08130	ENOG4108KS2	transglutaminase domain protein
I927_08135	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
I927_08140	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
I927_08145	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
I927_08150	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
I927_08155	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
I927_08160	ENOG41064N2	Protein of unknown function (DUF2726)
I927_08165	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
I927_08170	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
I927_08175	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
I927_08190	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
I927_08195	ENOG4105CIH	Imidazole acetol-phosphate transaminase
I927_08205	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
I927_08220	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
I927_08225	ENOG4105DMQ	Methyltransferase
I927_08230	ENOG4105CGH	5'-nucleotidase
I927_08235	ENOG4105CIC	tryptophan-specific transport protein
I927_08240	ENOG4105F0N	pyrophosphate phospho-hydrolase
I927_08245	ENOG4105ERG	peptidase m48, ste24p
I927_08255	ENOG41067XB	TonB family
I927_08260	ENOG4105M15	transport protein ExbD
I927_08265	ENOG4105M8K	biopolymer transport protein
I927_08270	ENOG4108JU6	CBS domain protein
I927_08275	ENOG4106KVJ	cytochrome C assembly protein
I927_08280	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I927_08285	ENOG4105E55	glycerol-3-phosphate acyltransferase
I927_08290	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
I927_08295	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
I927_08300	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
I927_08305	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
I927_08310	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
I927_08320	ENOG4105C5F	glutamine synthetase
I927_08325	ENOG4105CI3	gtp-binding protein typa
I927_08330	ENOG4105NX3	Membrane
I927_08340	ENOG4108R96	Methyltransferase, YaeB family
I927_08345	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
I927_08350	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
I927_08355	ENOG4105C8P	)-transporter
I927_08360	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
I927_08365	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
I927_08370	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
I927_08375	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
I927_08380	ENOG4105VG0	50S ribosomal protein l34
I927_08385	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
I927_08390	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
I927_08395	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
I927_08400	ENOG4105DVA	methyltransferase
I927_08405	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
I927_08410	ENOG4105YP7	UPF0270 protein
I927_08415	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
I927_08420	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
I927_08425	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
I927_08430	ENOG4105W5Q	DNA repair protein (RadC
I927_08435	ENOG4105KDC	50s ribosomal protein l28
I927_08440	ENOG4105W0E	50S ribosomal protein L33
I927_08445	ENOG4105S10	periplasmic binding protein
I927_08450	ENOG4105EHG	Permease protein
I927_08455	ENOG4108W0P	ABC transporter
I927_08460	ENOG4108VJC	ABC transporter, periplasmic molybdate-binding protein
I927_08465	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
I927_08490	ENOG4105VFB	Binds the 23S rRNA (By similarity)
I927_08495	ENOG4105EXC	Acyl-transferase
I927_08500	ENOG4107S6X	Glycosyl transferase, family 2
I927_08505	ENOG4105C25	Primosomal protein n'
I927_08510	ENOG41063M6	Cell Division Protein
I927_08515	ENOG4105Y7M	Transcriptional regulator, TetR family
I927_08520	ENOG410624X	efflux transporter, rnd family, mfp subunit
I927_08530	ENOG4105BZS	acriflavin resistance protein
I927_08540	ENOG4105K89	arsenate reductase
I927_08565	ENOG4105CH7	arginosuccinase
I927_08570	ENOG4105CAS	nag kinase
I927_08575	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
I927_08580	ENOG4105CWC	Acetylornithine deacetylase
I927_08585	ENOG4108ST3	glycosyltransferase
I927_08590	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
I927_08595	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
I927_08600	ENOG4105RT1	May be involved in cell division (By similarity)
I927_08605	ENOG4105C1J	atp-dependent rna helicase
I927_08610	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
I927_08615	ENOG4108VEN	abc transporter atp-binding protein
I927_08625	ENOG4107XNE	ABC transporter, periplasmic molybdate-binding protein
I927_08630	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
I927_08645	ENOG4105CFC	Transporter
I927_08650	ENOG4108IJ0	Aspartate ammonia-lyase
I927_08655	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
I927_08670	ENOG4108RXX	maleylacetoacetate isomerase
I927_08675	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
I927_08680	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
I927_08685	ENOG4105EXU	Membrane
I927_08690	ENOG4108IPT	Naphthoate synthase
I927_08700	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
I927_08705	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
I927_08710	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
I927_08715	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
I927_08720	ENOG4105RG0	Membrane
I927_08725	ENOG4108IA2	Sodium pantothenate symporter
I927_08730	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
I927_08735	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
I927_08740	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
I927_08760	ENOG4105ZRN	
I927_08765	ENOG4106DNP	
I927_08770	ENOG4105UGU	tonB-dependent Receptor
I927_08780	ENOG4105EHG	Permease protein
I927_08785	ENOG4107R4I	Periplasmic binding protein
I927_08805	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
I927_08820	ENOG4105CQ0	ABC transporter
I927_08825	ENOG4105D0C	transport protein
I927_08830	ENOG4105KZW	UPF0381 protein
I927_08835	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
I927_08840	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
I927_08845	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
I927_08850	ENOG4105EE5	Membrane protein terC
I927_08855	ENOG4105C2M	dna polymerase I
I927_08860	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
I927_08865	ENOG4105E61	Mannitol repressor protein
I927_08870	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
I927_08875	ENOG4105CTS	PTS system mannitol-specific
I927_08885	ENOG4105C4R	Atp-dependent dna helicase
I927_08895	ENOG4107VXZ	Hydrolase
I927_08905	ENOG4105W39	Membrane
I927_08910	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
I927_08915	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
I927_08920	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I927_08925	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
I927_08930	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
I927_08935	ENOG4108P11	EamA-like transporter family
I927_08940	ENOG4105D9M	gamma-glutamylcysteine synthetase
I927_08945	ENOG4105TRI	Hydrolase
I927_08950	ENOG4105C9A	Phoh family
I927_08955	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
I927_08975	ENOG4105DIJ	Phosphoethanolamine transferase
I927_08980	ENOG4108JA2	transcriptioN-repair coupling factor
I927_08985	ENOG4108HWV	)-transporter
I927_08990	ENOG4105C2J	ABC transporter
I927_08995	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
I927_09000	ENOG41060NJ	transcriptional regulator
I927_09005	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
I927_09010	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
I927_09015	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
I927_09020	ENOG4108JU5	Magnesium and cobalt efflux protein
I927_09025	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
I927_09030	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
I927_09035	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
I927_09040	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
I927_09045	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
I927_09050	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
I927_09055	ENOG4105GPY	SprT protein
I927_09065	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
I927_09070	ENOG4105KUZ	arsenate reductase
I927_09075	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
I927_09095	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
I927_09105	ENOG4107ZF2	Phosphatase
I927_09110	ENOG4105DAY	polysaccharide export protein
I927_09120	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
I927_09140	ENOG4105D3Q	Sugar transferase
I927_09155	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
I927_09165	ENOG4105C5E	polysaccharide biosynthesis protein
I927_09185	ENOG4107QQG	Dehydrogenase
I927_09190	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
I927_09195	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
I927_09200	ENOG4108478	ec 3.2.1.18
I927_09210	ENOG4107ZJM	MltA-interacting protein MipA
I927_09215	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
I927_09220	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
I927_09225	ENOG4105C28	cystathionine
I927_09230	ENOG4105K63	Thioredoxin
I927_09235	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
I927_09240	ENOG4105EI2	Pseudouridine synthase
I927_09245	ENOG4105C03	ribonuclease
I927_09255	ENOG4105D3Y	Na H antiporter
I927_09260	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
I927_09265	ENOG4108UYE	Lactoylglutathione lyase
I927_09275	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
I927_09280	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
I927_09285	ENOG4105C9M	aspartyl-trna synthetase
I927_09295	ENOG4108TIT	dATP pyrophosphohydrolase
I927_09300	ENOG4105CDY	transcriptional regulatory protein
I927_09310	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
I927_09315	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
I927_09320	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
I927_09330	ENOG4105C4M	(Ubiquinol oxidase) subunit I
I927_09335	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
I927_09350	ENOG4107YD3	Thioesterase
I927_09355	ENOG4105E02	MotA TolQ exbB proton channel
I927_09370	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
I927_09375	ENOG4105KCK	Peptidoglycan-associated lipoprotein
I927_09405	ENOG4105DSY	exodeoxyribonuclease V, gamma
I927_09410	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
I927_09415	ENOG4108WPU	DNA polymerase III subunit psi
I927_09420	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
I927_09425	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
I927_09430	ENOG4107RCV	ABC transporter, permease
I927_09435	ENOG4105C4Y	ABC transporter
I927_09440	ENOG4105C4Y	ABC transporter
I927_09445	ENOG4105C4Y	ABC transporter
I927_09450	ENOG4105DBI	uridine monophosphokinase
I927_09455	ENOG4105DHP	deoxycytidine triphosphate deaminase
I927_09465	ENOG4105F27	Major Facilitator
I927_09470	ENOG4105CHH	sulfate transporter
I927_09475	ENOG4108UHU	Aldolase
I927_09485	ENOG4105C8N	cysteinyl-tRNA synthetase
I927_09490	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
I927_09495	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
I927_09500	ENOG4105EYA	deoxyribonuclease
I927_09510	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
I927_09515	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
I927_09520	ENOG4105CA0	peroxidase
I927_09525	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
I927_09530	ENOG4105CFH	Aspartokinase
I927_09535	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
I927_09540	ENOG4105EN6	Membrane
I927_09550	ENOG4105CEE	C4-dicarboxylate transporter
I927_09565	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
I927_09570	ENOG4105DFU	Cell wall formation (By similarity)
I927_09575	ENOG4105CA3	membrane-bound lytic murein transglycosylase
I927_09580	ENOG4105CUZ	uba thif-type nad fad binding protein
I927_09585	ENOG4105NXV	High-affinity zinc uptake system protein
I927_09590	ENOG4108IQE	Amp-dependent synthetase and ligase
I927_09600	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
I927_09605	ENOG4105E0X	reductase
I927_09610	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
I927_09615	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
I927_09620	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
I927_09625	ENOG4105CB5	ATP-dependent DNA helicase recG
I927_09630	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
I927_09635	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
I927_09655	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
I927_09670	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
I927_09675	ENOG4105D1F	ATP-binding protein
I927_09680	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
I927_09685	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
I927_09700	ENOG4105M6W	Crispr-associated protein, Csy3 family
I927_09720	ENOG4107SV5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
I927_09730	ENOG4105BZU	Histidine kinase
I927_09740	ENOG4105ECY	inositol monophosphatase
I927_09745	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
I927_09750	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
I927_09755	ENOG4105C3J	Cysteine desulfurase
I927_09760	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
I927_09765	ENOG4108Z4V	iron-sulfur cluster assembly
I927_09770	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
I927_09775	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
I927_09780	ENOG4108ZIT	Ferredoxin, 2FE-2S
I927_09785	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
I927_09790	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
I927_09795	ENOG4107SC1	transglycosylase
I927_09800	ENOG4105K9H	YciI-like protein
I927_09805	ENOG4105NAU	thioesterase Superfamily protein
I927_09810	ENOG4107835	probably involved in intracellular septation (By similarity)
I927_09820	ENOG4105EIF	outer membrane protein W
I927_09825	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
I927_09830	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
I927_09835	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
I927_09840	ENOG4107R6U	sodium dicarboxylate symporter
I927_09845	ENOG4108MVK	Receptor
I927_09850	ENOG4108MVK	Receptor
I927_09855	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
I927_09860	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
I927_09865	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
I927_09870	ENOG4105CK7	Sodium proline symporter
I927_09875	ENOG4105C03	ribonuclease
I927_09880	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
I927_09885	ENOG4105C8Y	Acetylornithine aminotransferase
I927_09890	ENOG4105WPN	DNA integration recombination invertion protein
I927_09895	ENOG4105EAH	synthase
I927_09900	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
I927_09905	ENOG4105K46	50S ribosomal protein l27
I927_09920	ENOG4105QYV	Membrane
I927_09925	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
I927_09930	ENOG41090R7	Ferric uptake
I927_09935	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
I927_09940	ENOG4105NNH	LexA regulated protein
I927_09945	ENOG4105EV9	Alpha Beta Hydrolase
I927_09950	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
I927_09965	ENOG4105EGS	Mechanosensitive ion channel
I927_09970	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
I927_09975	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
I927_09980	ENOG4105EJ9	Membrane
I927_09985	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
I927_09990	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
I927_10005	ENOG4105EEQ	Na H antiporter
I927_10010	ENOG4105M4H	endoribonuclease L-psp
I927_10015	ENOG4108VTV	Inherit from NOG: Membrane
I927_10025	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
I927_10030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
I927_10035	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
I927_10050	ENOG4106R49	Methyltransferase
I927_10055	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
I927_10060	ENOG4105DP9	ABC transporter
I927_10065	ENOG4106SMU	thiamine transporter membrane protein
I927_10070	ENOG4107T0D	ABC, transporter
I927_10075	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
I927_10080	ENOG4105C8J	)-transporter
I927_10085	ENOG4105CSM	endonuclease III
I927_10090	ENOG4105DZB	Electron transport complex
I927_10095	ENOG4108UQQ	Electron transport complex
I927_10100	ENOG4105D6A	Electron transport complex
I927_10105	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
I927_10110	ENOG4108R3D	Electron transport complex
I927_10115	ENOG4105DGN	Electron transport complex
I927_10130	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
I927_10135	ENOG4108DG9	Smr protein MutS2
I927_10140	ENOG4105EM2	membrane
I927_10145	ENOG410901E	Membrane
I927_10150	ENOG4108Z5K	methylglyoxal synthase
I927_10155	ENOG41068P6	UPF0319 protein
I927_10160	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
I927_10165	ENOG4105CC5	ABC transporter
I927_10170	ENOG4105CC5	ABC transporter
I927_10175	ENOG4105DIK	(ABC) transporter
I927_10185	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
I927_10190	ENOG4108MN8	Membrane
I927_10195	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
I927_10200	ENOG4108MG3	formate dehydrogenase
I927_10205	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
I927_10210	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
I927_10215	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
I927_10220	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
I927_10225	ENOG4105C4R	Atp-dependent dna helicase
I927_10230	ENOG4105CDU	Replicative dna helicase
I927_10235	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
I927_10245	ENOG4107QP8	phosphohexose isomerase
I927_10265	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
I927_10270	ENOG4105DZ2	Transcriptional regulator
I927_10275	ENOG4108UMN	azlc family
I927_10280	ENOG4105KMT	branched-chain amino acid
I927_10285	ENOG4106CC8	Bacterial inner membrane protein
I927_10290	ENOG4105C5H	ABC transporter
I927_10295	ENOG41065CD	Exported protein
I927_10300	ENOG4105D7X	high-affinity nickel-transporter
I927_10310	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
I927_10320	ENOG4105BZU	Histidine kinase
I927_10325	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
I927_10330	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
I927_10335	ENOG4105E2Z	phosphate ABC transporter (Permease
I927_10340	ENOG4105C8U	phosphate abc transporter
I927_10345	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
I927_10350	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
I927_10355	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
I927_10360	ENOG4105EEI	dihydropteroate synthase
I927_10365	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
I927_10370	ENOG4108BY2	phosphohistidine phosphatase
I927_10380	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
I927_10385	ENOG4107M7T	YcgL domain
I927_10405	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
I927_10415	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
I927_10430	ENOG4107SJW	iron permease, FTR1
I927_10435	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
I927_10440	ENOG4105EZR	dyp-type peroxidase family protein
I927_10445	ENOG4105BZ4	penicillin-binding protein
I927_10450	ENOG4108ZIG	UPF0231 protein
I927_10455	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
I927_10460	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
I927_10465	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
I927_10475	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
I927_10480	ENOG4105ESV	Glycosyl transferase, family 4