locus-tag	class	description
I927_00005	COG0024	Methionine aminopeptidase
I927_00040	COG2431	L-lysine efflux transmembrane transporter activity
I927_00045	COG3593	DNA synthesis involved in DNA repair
I927_00060	COG3101	peptidyl-lysine hydroxylation
I927_00065	COG1131	(ABC) transporter
I927_00070	COG0842	Transport permease protein
I927_00090	COG1611	Belongs to the LOG family
I927_00100	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
I927_00105	COG3098	single-species biofilm formation
I927_00120	COG1278	Cold shock
I927_00145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I927_00150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I927_00195	COG2831	hemolysin activation secretion protein
I927_00200	COG3210	domain, Protein
I927_00200	COG3210	domain, Protein
I927_00265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
I927_00280	COG3306	glycosyltransferase involved in LPS biosynthesis
I927_00290	COG1216	Glycosyl transferase, family 2
I927_00295	COG1216	Glycosyl transferase, family 2
I927_00300	COG2951	lytic endotransglycosylase activity
I927_00305	COG2252	PERMEase
I927_00310	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
I927_00315	COG1074	ATP-dependent DNA helicase activity
I927_00320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I927_00325	COG2999	glutathione oxidoreductase activity
I927_00350	COG2969	positive regulation of protein catabolic process
I927_00355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
I927_00360	COG0517	IMP dehydrogenase activity
I927_00360	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
I927_00375	COG1538	Outer membrane efflux protein
I927_00385	COG1115	amino acid carrier protein
I927_00405	COG0142	geranyltranstransferase activity
I927_00440	COG1640	4-alpha-glucanotransferase
I927_00450	COG1523	belongs to the glycosyl hydrolase 13 family
I927_00480	COG1090	epimerase
I927_00500	COG3102	Protein conserved in bacteria
I927_00510	COG3133	Outer membrane lipoprotein
I927_00540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I927_00545	COG4591	ABC-type transport system involved in lipoprotein release permease component
I927_00555	COG4591	ABC-type transport system involved in lipoprotein release permease component
I927_00560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I927_00565	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
I927_00570	COG0402	S-adenosylhomocysteine deaminase activity
I927_00575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I927_00580	COG0583	DNA-binding transcription factor activity
I927_00590	COG2833	Protein of unknown function (DUF455)
I927_00595	COG1946	Acyl-CoA thioesterase
I927_00600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
I927_00605	COG4988	ABC transporter
I927_00610	COG0492	ferredoxin-NADP+ reductase activity
I927_00615	COG3118	belongs to the thioredoxin family
I927_00620	COG0288	reversible hydration of carbon dioxide
I927_00635	COG4221	oxidoreductase activity
I927_00655	COG0512	Glutamine amidotransferase of anthranilate synthase
I927_00660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I927_00665	COG0616	signal peptide processing
I927_00680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I927_00700	COG0747	negative chemotaxis
I927_00710	COG0730	response to heat
I927_00715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I927_00725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
I927_00770	COG0697	spore germination
I927_00775	COG2925	Exonuclease
I927_00780	COG4575	ribosome binding
I927_00805	COG0613	PHP domain protein
I927_00815	COG0308	aminopeptidase N
I927_00820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
I927_00825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
I927_00830	COG1448	Aminotransferase
I927_00840	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
I927_00860	COG0791	NLP P60 protein
I927_00890	COG0564	pseudouridine synthase activity
I927_00895	COG0406	alpha-ribazole phosphatase activity
I927_00900	COG0285	dihydrofolate synthase activity
I927_00925	COG0586	Pfam SNARE associated Golgi protein
I927_00935	COG1940	carbohydrate kinase activity
I927_00945	COG4953	penicillin-binding protein 1C
I927_00965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
I927_00970	COG2823	Periplasmic or secreted lipoprotein
I927_00975	COG0307	riboflavin synthase, alpha
I927_00985	COG0673	inositol 2-dehydrogenase activity
I927_00990	COG0469	pyruvate kinase activity
I927_00995	COG0582	viral genome integration into host DNA
I927_01060	COG1802	Transcriptional regulator
I927_01060	COG4626	Terminase
I927_01115	COG1278	Cold shock
I927_01140	COG0583	DNA-binding transcription factor activity
I927_01150	COG0009	L-threonylcarbamoyladenylate synthase
I927_01160	COG4409	exo-alpha-(2->6)-sialidase activity
I927_01165	COG0287	Prephenate dehydrogenase
I927_01165	COG1605	Chorismate mutase
I927_01170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I927_01175	COG1528	Iron-storage protein
I927_01180	COG1528	Iron-storage protein
I927_01195	COG0589	response to stress
I927_01205	COG0616	signal peptide processing
I927_01210	COG0778	Nitroreductase
I927_01220	COG0515	serine threonine protein kinase
I927_01235	COG0671	phosphoesterase, PA-phosphatase related
I927_01245	COG4166	transmembrane transport
I927_01250	COG2832	Protein of unknown function (DUF454)
I927_01255	COG0339	signal peptide processing
I927_01270	COG1940	carbohydrate kinase activity
I927_01270	COG1846	Transcriptional regulator
I927_01285	COG2226	methyltransferase
I927_01290	COG1944	ATP diphosphatase activity
I927_01295	COG3105	Protein conserved in bacteria
I927_01305	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
I927_01310	COG0708	Exodeoxyribonuclease III
I927_01330	COG0303	'Molybdopterin
I927_01335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I927_01340	COG0163	prenyltransferase activity
I927_01350	COG1286	toxin biosynthetic process
I927_01365	COG0857	belongs to the CobB CobQ family
I927_01365	COG0280	phosphate acetyltransferase
I927_01370	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
I927_01375	COG0318	PFAM AMP-dependent synthetase and ligase
I927_01380	COG3065	identical protein binding
I927_01385	COG1214	PFAM Peptidase M22, glycoprotease
I927_01390	COG1199	ATP-dependent helicase activity
I927_01395	COG0676	glucose-6-phosphate 1-epimerase activity
I927_01405	COG1534	Rna-binding protein
I927_01420	COG2027	D-alanyl-D-alanine carboxypeptidase
I927_01435	COG0733	neurotransmitter:sodium symporter activity
I927_01445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I927_01450	COG0633	Ferredoxin
I927_01485	COG1280	lysine exporter protein (LysE YggA)
I927_01490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I927_01495	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
I927_01510	COG0814	amino acid
I927_01515	COG0778	Nitroreductase
I927_01520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I927_01525	COG5339	Protein conserved in bacteria
I927_01555	COG1629	transport
I927_01555	COG4771	TonB-dependent receptor
I927_01565	COG4149	molybdate abc transporter
I927_01570	COG0725	ABC transporter, periplasmic molybdate-binding protein
I927_01580	COG2005	Transcriptional regulator
I927_01590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I927_01595	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I927_01595	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I927_01610	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
I927_01615	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
I927_01620	COG1353	crispr-associated protein
I927_01630	COG1337	RAMP superfamily
I927_01675	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
I927_01680	COG1518	maintenance of DNA repeat elements
I927_01685	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
I927_01725	COG0195	Participates in both transcription termination and antitermination
I927_01755	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
I927_01770	COG1643	Atp-dependent helicase
I927_01775	COG2363	Small membrane protein
I927_01810	COG0463	Glycosyl transferase, family 2
I927_01840	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
I927_01850	COG1704	LemA family
I927_01855	COG2885	chlorophyll binding
I927_01855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
I927_01860	COG0247	lactate metabolic process
I927_01860	COG0277	FAD linked oxidase domain protein
I927_01880	COG1609	Transcriptional regulator
I927_01885	COG3265	gluconokinase activity
I927_01895	COG0626	cystathionine gamma-synthase activity
I927_01900	COG0450	alkyl hydroperoxide reductase
I927_01905	COG0023	Translation Initiation Factor
I927_01915	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
I927_01920	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
I927_01930	COG0539	negative regulation of cytoplasmic translation
I927_01940	COG4771	TonB-dependent receptor
I927_01945	COG0612	Peptidase, M16
I927_01955	COG1982	Orn Lys Arg decarboxylase major
I927_01960	COG0531	amino acid
I927_01970	COG2990	Protein conserved in bacteria
I927_01975	COG0814	amino acid
I927_01995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I927_02005	COG2194	sulfuric ester hydrolase activity
I927_02015	COG0783	Belongs to the Dps family
I927_02040	COG2927	DNA polymerase III (CHI subunit)
I927_02070	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
I927_02090	COG3716	PTS system mannose fructose sorbose family IID component
I927_02095	COG3715	PTS system
I927_02100	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I927_02100	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I927_02105	COG2814	Major facilitator Superfamily
I927_02135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I927_02140	COG3094	Invasion gene expression up-regulator, SirB
I927_02190	COG4964	Belongs to the GSP D family
I927_02210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I927_02240	COG2333	competence protein COMEC
I927_02240	COG0658	competence protein
I927_02245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I927_02250	COG0617	tRNA 3'-terminal CCA addition
I927_02255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
I927_02265	COG2949	membrane
I927_02270	COG1609	Transcriptional regulator
I927_02275	COG0440	acetolactate synthase activity
I927_02280	COG0028	Belongs to the TPP enzyme family
I927_02285	COG1757	Na H antiporter
I927_02290	COG2916	Histone family protein nucleoid-structuring protein H-NS
I927_02295	COG0788	formyltetrahydrofolate deformylase activity
I927_02300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I927_02310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I927_02310	COG2190	(PTS) system
I927_02310	COG1263	PTS System
I927_02325	COG1346	cytolysis
I927_02335	COG1525	nuclease
I927_02345	COG2166	iron-sulfur cluster assembly
I927_02355	COG1560	Kdo2-lipid A biosynthetic process
I927_02360	COG3381	protein complex oligomerization
I927_02365	COG2249	NAD(P)H dehydrogenase (quinone) activity
I927_02375	COG0330	HflC and HflK could
I927_02380	COG1119	ATPase activity
I927_02390	COG2932	Transcriptional regulator
I927_02395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I927_02400	COG0508	dehydrogenase complex catalyzes the overall conversion of
I927_02405	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
I927_02410	COG2190	(PTS) system
I927_02415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I927_02420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I927_02435	COG0802	atpase or kinase
I927_02440	COG0860	N-Acetylmuramoyl-L-alanine amidase
I927_02440	COG1388	LysM domain
I927_02460	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I927_02465	COG3283	Transcriptional regulator of aromatic amino acids metabolism
I927_02475	COG3106	COG3106 Predicted ATPase
I927_02480	COG4166	transmembrane transport
I927_02485	COG4168	peptide transport system, permease
I927_02490	COG4171	peptide transport system, permease
I927_02495	COG4172	Belongs to the ABC transporter superfamily
I927_02500	COG4172	Belongs to the ABC transporter superfamily
I927_02515	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
I927_02515	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
I927_02535	COG4977	sequence-specific DNA binding
I927_02570	COG2252	PERMEase
I927_02580	COG2814	Major facilitator Superfamily
I927_02590	COG0546	phosphoglycolate phosphatase activity
I927_02595	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I927_02610	COG0508	dehydrogenase complex catalyzes the overall conversion of
I927_02615	COG0567	Dehydrogenase, E1 component
I927_02620	COG0372	Belongs to the citrate synthase family
I927_02640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I927_02645	COG3108	Peptidase M15
I927_02650	COG2989	Protein conserved in bacteria
I927_02670	COG2995	paraquat-inducible protein a
I927_02675	COG3008	intermembrane lipid transfer
I927_02690	COG1176	ABC-type spermidine putrescine transport system, permease component I
I927_02695	COG1177	transmembrane transport
I927_02700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
I927_02705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
I927_02720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
I927_02735	COG1522	sequence-specific DNA binding
I927_02745	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
I927_02750	COG3025	triphosphatase activity
I927_02755	COG1392	Phosphate transport regulator
I927_02760	COG0306	phosphate transporter
I927_02765	COG4991	sh3 domain protein
I927_02790	COG0739	heme binding
I927_02800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I927_02805	COG4608	Belongs to the ABC transporter superfamily
I927_02810	COG0444	Belongs to the ABC transporter superfamily
I927_02815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I927_02820	COG0601	transmembrane transport
I927_02825	COG0747	negative chemotaxis
I927_02830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
I927_02870	COG0561	phosphatase activity
I927_02880	COG1862	Preprotein translocase
I927_02885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I927_02890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I927_02925	COG0257	Belongs to the bacterial ribosomal protein bL36 family
I927_02930	COG0745	RESPONSE REGULATOR receiver
I927_02945	COG3585	molybdate ion transport
I927_02950	COG0642	Histidine kinase
I927_02955	COG0745	RESPONSE REGULATOR receiver
I927_02965	COG2259	Doxx family
I927_02980	COG3219	Protein conserved in bacteria
I927_02990	COG1595	DNA-templated transcription, initiation
I927_03020	COG1840	ABC-type Fe3 transport system, periplasmic component
I927_03030	COG1053	succinate dehydrogenase
I927_03035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I927_03050	COG0795	lipopolysaccharide-transporting ATPase activity
I927_03055	COG0795	lipopolysaccharide-transporting ATPase activity
I927_03070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I927_03075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
I927_03100	COG1083	cytidylyl-transferase
I927_03110	COG0720	synthase
I927_03115	COG0602	queuosine metabolic process
I927_03130	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
I927_03145	COG5007	Belongs to the BolA IbaG family
I927_03150	COG3113	response to antibiotic
I927_03155	COG2854	intermembrane phospholipid transfer
I927_03160	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
I927_03165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
I927_03170	COG1127	ABC transporter
I927_03175	COG3117	lipopolysaccharide transmembrane transporter activity
I927_03180	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
I927_03185	COG1137	ATPase activity
I927_03190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I927_03205	COG2850	peptidyl-arginine hydroxylation
I927_03215	COG2867	negative regulation of translational initiation
I927_03230	COG0531	amino acid
I927_03240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I927_03245	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
I927_03250	COG2824	Alkylphosphonate utilization operon protein PhnA
I927_03270	COG1172	Belongs to the binding-protein-dependent transport system permease family
I927_03275	COG1879	ABC-type sugar transport system periplasmic component
I927_03280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I927_03290	COG1605	Chorismate mutase
I927_03290	COG0077	Prephenate dehydratase
I927_03295	COG1979	alcohol dehydrogenase
I927_03305	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
I927_03310	COG0849	cell division
I927_03315	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
I927_03350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I927_03360	COG0768	penicillin binding
I927_03365	COG3116	cell division
I927_03380	COG1966	Carbon starvation protein
I927_03385	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
I927_03390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I927_03395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I927_03400	COG1120	ATPase activity
I927_03410	COG4160	amino acid transport
I927_03415	COG4215	(ABC) transporter
I927_03420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I927_03425	COG1126	abc transporter atp-binding protein
I927_03435	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
I927_03440	COG0312	modulator of DNA gyrase
I927_03450	COG0330	HflC and HflK could
I927_03455	COG0330	HflC and HflK could
I927_03465	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
I927_03475	COG0527	aspartate kinase activity
I927_03475	COG0460	homoserine dehydrogenase
I927_03525	COG0204	Acyl-transferase
I927_03535	COG5413	integral membrane protein
I927_03545	COG1509	lysine 2,3-aminomutase activity
I927_03550	COG3266	domain, Protein
I927_03550	COG3061	Opacity-associated protein A
I927_03570	COG2814	Major facilitator Superfamily
I927_03580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
I927_03585	COG1115	amino acid carrier protein
I927_03610	COG1459	type II secretion system
I927_03615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I927_03620	COG4969	Belongs to the N-Me-Phe pilin family
I927_03625	COG3023	N-Acetylmuramoyl-L-alanine amidase
I927_03635	COG0730	response to heat
I927_03650	COG0590	tRNA wobble adenosine to inosine editing
I927_03655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I927_03665	COG1882	Formate acetyltransferase
I927_03670	COG2116	formate transmembrane transporter activity
I927_03675	COG0537	adenosine 5'-monophosphoramidase activity
I927_03700	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I927_03730	COG0681	Belongs to the peptidase S26 family
I927_03755	COG2267	carboxylic ester hydrolase activity
I927_03775	COG0436	Aminotransferase
I927_03790	COG3842	ATPase activity
I927_03820	COG2095	MarC family integral membrane protein
I927_03825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I927_03830	COG0748	coenzyme F420 binding
I927_03835	COG4178	(ABC) transporter
I927_03850	COG0121	glutamine amidotransferase
I927_03855	COG0814	amino acid
I927_03860	COG1760	l-serine dehydratase
I927_03865	COG3738	Protein conserved in bacteria
I927_03875	COG0753	catalase activity
I927_03880	COG2081	HI0933 family
I927_03885	COG4235	cytochrome complex assembly
I927_03885	COG3088	subunit of a heme lyase
I927_03890	COG3088	subunit of a heme lyase
I927_03890	COG4235	cytochrome complex assembly
I927_03900	COG1138	Cytochrome C-type biogenesis protein
I927_03905	COG3301	Polysulphide reductase, NrfD
I927_03910	COG0437	4 iron, 4 sulfur cluster binding
I927_03915	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
I927_03935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
I927_03950	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
I927_03965	COG0346	lactoylglutathione lyase activity
I927_03990	COG1138	Cytochrome C-type biogenesis protein
I927_04000	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I927_04005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I927_04010	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I927_04020	COG2814	Major facilitator Superfamily
I927_04030	COG0281	malic enzyme
I927_04030	COG0280	phosphate acetyltransferase
I927_04040	COG0737	Belongs to the 5'-nucleotidase family
I927_04060	COG2976	Protein conserved in bacteria
I927_04075	COG1426	Protein conserved in bacteria
I927_04080	COG3063	Type IV pilus biogenesis stability protein PilW
I927_04090	COG0628	permease
I927_04100	COG0521	Mo-molybdopterin cofactor biosynthetic process
I927_04105	COG4589	Belongs to the CDS family
I927_04115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I927_04120	COG0490	domain, Protein
I927_04120	COG0471	metal ion transport
I927_04165	COG0575	Belongs to the CDS family
I927_04200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I927_04205	COG0842	Transport permease protein
I927_04205	COG1129	ABC transporter
I927_04210	COG0842	Transport permease protein
I927_04215	COG1538	Outer membrane efflux protein
I927_04220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I927_04225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
I927_04245	COG1652	LysM domain
I927_04250	COG2321	neutral zinc metallopeptidase
I927_04255	COG3730	PTS system glucitol sorbitol-specific
I927_04270	COG1028	Short-chain dehydrogenase reductase Sdr
I927_04275	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
I927_04280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I927_04285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I927_04290	COG1349	DNA-binding transcription factor activity
I927_04320	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
I927_04325	COG1792	Involved in formation and maintenance of cell shape
I927_04335	COG0557	exoribonuclease II activity
I927_04385	COG0583	DNA-binding transcription factor activity
I927_04415	COG0789	Transcriptional regulator
I927_04420	COG0798	PFAM Bile acid sodium symporter
I927_04425	COG0798	PFAM Bile acid sodium symporter
I927_04440	COG2132	Multicopper oxidase
I927_04445	COG0798	PFAM Bile acid sodium symporter
I927_04520	COG1686	Belongs to the peptidase S11 family
I927_04530	COG0772	Belongs to the SEDS family
I927_04535	COG0768	penicillin binding
I927_04545	COG0799	negative regulation of ribosome biogenesis
I927_04555	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
I927_04565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
I927_04575	COG1028	Short-chain dehydrogenase reductase Sdr
I927_04580	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I927_04600	COG1399	metal-binding, possibly nucleic acid-binding protein
I927_04610	COG0601	transmembrane transport
I927_04615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I927_04625	COG4608	Belongs to the ABC transporter superfamily
I927_04640	COG0500	methyltransferase
I927_04645	COG2830	Protein of unknown function (DUF452)
I927_04655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I927_04665	COG0545	Peptidyl-prolyl cis-trans isomerase
I927_04680	COG2966	Psort location CytoplasmicMembrane, score
I927_04685	COG3610	response to peptide
I927_04690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
I927_04695	COG2217	Heavy metal translocating P-type atpase
I927_04700	COG2608	mercury ion transmembrane transporter activity
I927_04710	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
I927_04715	COG2205	protein histidine kinase activity
I927_04720	COG0745	RESPONSE REGULATOR receiver
I927_04725	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I927_04740	COG3083	sulfuric ester hydrolase activity
I927_04745	COG0402	S-adenosylhomocysteine deaminase activity
I927_04750	COG1011	Hydrolase
I927_04780	COG1561	YicC-like family, N-terminal region
I927_04785	COG0354	folic acid binding
I927_04825	COG1385	rRNA (uridine-N3-)-methyltransferase activity
I927_04840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I927_04845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
I927_04850	COG3307	-O-antigen
I927_04855	COG0191	fructose-bisphosphate aldolase activity
I927_04865	COG3719	Belongs to the RNase T2 family
I927_04870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
I927_04875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I927_04880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I927_04885	COG1556	Lactate utilization protein
I927_04890	COG1139	Iron-sulfur cluster binding protein
I927_04895	COG0247	lactate metabolic process
I927_04900	COG1620	l-lactate permease
I927_04905	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I927_04915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I927_04920	COG1621	beta-fructofuranosidase activity
I927_04940	COG0859	PFAM glycosyl transferase family 9
I927_04945	COG0859	PFAM glycosyl transferase family 9
I927_04955	COG0513	Belongs to the DEAD box helicase family
I927_04965	COG3201	nicotinamide mononucleotide transporter
I927_04990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I927_04995	COG0778	Nitroreductase
I927_05040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
I927_05050	COG0577	efflux transmembrane transporter activity
I927_05050	COG1136	(ABC) transporter
I927_05090	COG3071	HemY protein
I927_05095	COG2959	enzyme of heme biosynthesis
I927_05115	COG2197	response regulator
I927_05120	COG0729	surface antigen
I927_05125	COG2911	Protein conserved in bacteria
I927_05130	COG0248	Ppx GppA phosphatase
I927_05155	COG3085	chromosome segregation
I927_05160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I927_05165	COG3084	Protein conserved in bacteria
I927_05180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I927_05180	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
I927_05185	COG1105	Belongs to the carbohydrate kinase PfkB family
I927_05190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I927_05190	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
I927_05190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I927_05205	COG3005	denitrification pathway
I927_05215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I927_05225	COG1595	DNA-templated transcription, initiation
I927_05230	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
I927_05235	COG3026	antisigma factor binding
I927_05240	COG3086	response to oxidative stress
I927_05245	COG1763	Mo-molybdopterin cofactor biosynthetic process
I927_05250	COG2814	Major facilitator Superfamily
I927_05270	COG1957	nucleoside hydrolase
I927_05275	COG3276	selenocysteine insertion sequence binding
I927_05280	COG2221	Nitrite and sulphite reductase 4Fe-4S
I927_05280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
I927_05285	COG3381	protein complex oligomerization
I927_05290	COG3302	dmso reductase anchor subunit
I927_05295	COG0437	4 iron, 4 sulfur cluster binding
I927_05300	COG0243	molybdopterin cofactor binding
I927_05305	COG1285	pathogenesis
I927_05310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I927_05310	COG2190	(PTS) system
I927_05310	COG1263	PTS System
I927_05345	COG2610	gluconate transmembrane transporter activity
I927_05350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I927_05365	COG3622	Belongs to the hyi family
I927_05370	COG0235	Class ii aldolase
I927_05375	COG3395	kinase activity
I927_05380	COG2084	Dehydrogenase
I927_05385	COG1349	DNA-binding transcription factor activity
I927_05390	COG2195	Cleaves the N-terminal amino acid of tripeptides
I927_05405	COG1070	Carbohydrate kinase
I927_05410	COG2115	Belongs to the xylose isomerase family
I927_05420	COG1757	Na H antiporter
I927_05425	COG4213	ABC transporter substrate-binding protein
I927_05430	COG1129	ABC transporter
I927_05435	COG4214	carbohydrate transport
I927_05440	COG1609	Transcriptional regulator
I927_05440	COG2207	Transcriptional regulator
I927_05460	COG1940	carbohydrate kinase activity
I927_05470	COG1879	ABC-type sugar transport system periplasmic component
I927_05475	COG1172	Belongs to the binding-protein-dependent transport system permease family
I927_05485	COG4191	Histidine kinase
I927_05485	COG0784	Response regulator, receiver
I927_05500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I927_05505	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
I927_05515	COG2960	long-chain fatty acid transporting porin activity
I927_05520	COG3172	ATPase kinase involved in NAD metabolism
I927_05525	COG2129	metallophosphoesterase
I927_05560	COG0201	protein transport
I927_05570	COG1841	ribosomal large subunit assembly
I927_05610	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
I927_05635	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
I927_05640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
I927_05665	COG0051	transcription antitermination factor activity, RNA binding
I927_05675	COG0038	chloride channel
I927_05715	COG0019	diaminopimelate decarboxylase activity
I927_05730	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
I927_05745	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
I927_05750	COG1045	serine acetyltransferase
I927_05765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I927_05770	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
I927_05775	COG0433	COG0433 Predicted ATPase
I927_05790	COG0705	Rhomboid family
I927_05795	COG1349	DNA-binding transcription factor activity
I927_05800	COG0247	lactate metabolic process
I927_05810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I927_05815	COG2271	Major facilitator Superfamily
I927_05820	COG0584	glycerophosphoryl diester phosphodiesterase
I927_05825	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
I927_05875	COG2183	response to ionizing radiation
I927_05895	COG1584	GPR1 FUN34 yaaH family protein
I927_05900	COG1454	alcohol dehydrogenase
I927_05900	COG1012	belongs to the aldehyde dehydrogenase family
I927_05905	COG3842	ATPase activity
I927_05910	COG1178	ABC-type Fe3 transport system permease component
I927_05915	COG3842	ATPase activity
I927_05925	COG1840	ABC-type Fe3 transport system, periplasmic component
I927_05945	COG0512	Glutamine amidotransferase of anthranilate synthase
I927_05955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I927_05980	COG1881	PFAM PEBP family protein
I927_05985	COG1733	regulation of RNA biosynthetic process
I927_05995	COG1132	(ABC) transporter
I927_06000	COG4988	ABC transporter
I927_06005	COG0697	spore germination
I927_06010	COG0187	DNA topoisomerase II activity
I927_06030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I927_06035	COG0640	Transcriptional regulator
I927_06040	COG1494	fructose-1,6-bisphosphatase
I927_06115	COG1739	Uncharacterized protein family UPF0029
I927_06120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I927_06140	COG2853	Lipoprotein
I927_06170	COG4942	peptidase
I927_06175	COG2861	carbohydrate metabolic process
I927_06185	COG0606	chelatase, subunit chli
I927_06195	COG2990	Protein conserved in bacteria
I927_06200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
I927_06215	COG0742	ribosomal rna small subunit methyltransferase
I927_06225	COG0552	protein localization to endoplasmic reticulum
I927_06230	COG2884	Cell division ATP-binding protein ftsE
I927_06235	COG2177	Part of the ABC transporter FtsEX involved in
I927_06280	COG1012	belongs to the aldehyde dehydrogenase family
I927_06285	COG3384	dioxygenase
I927_06295	COG2814	Major facilitator Superfamily
I927_06300	COG3971	2-oxopent-4-enoate hydratase activity
I927_06320	COG0494	nUDIX hydrolase
I927_06325	COG1011	Hydrolase
I927_06330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
I927_06340	COG1218	3'(2'),5'-bisphosphate nucleotidase
I927_06345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
I927_06350	COG0363	glucosamine-6-phosphate deaminase activity
I927_06355	COG0625	glutathione transferase activity
I927_06380	COG1040	competence protein
I927_06390	COG3070	regulator of competence-specific genes
I927_06410	COG1215	transferase activity, transferring glycosyl groups
I927_06415	COG0569	domain protein
I927_06425	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
I927_06440	COG2841	Protein conserved in bacteria
I927_06445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I927_06460	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
I927_06465	COG1522	sequence-specific DNA binding
I927_06510	COG2095	MarC family integral membrane protein
I927_06525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
I927_06530	COG0471	metal ion transport
I927_06535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I927_06540	COG1275	C4-dicarboxylate transporter malic acid transport protein
I927_06570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
I927_06575	COG3062	negative regulation of establishment of protein localization
I927_06585	COG0437	4 iron, 4 sulfur cluster binding
I927_06590	COG0348	domain, Protein
I927_06595	COG3043	anaerobic respiration
I927_06600	COG3005	denitrification pathway
I927_06605	COG0758	DNA mediated transformation
I927_06615	COG2818	Glycosylase
I927_06640	COG0538	isocitrate dehydrogenase activity
I927_06675	COG1238	metal cluster binding
I927_06685	COG1388	LysM domain
I927_06685	COG4942	peptidase
I927_06710	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I927_06745	COG1794	racemase activity, acting on amino acids and derivatives
I927_06750	COG3978	acetolactate synthase activity
I927_06760	COG0561	phosphatase activity
I927_06775	COG2267	carboxylic ester hydrolase activity
I927_06780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I927_06790	COG0561	phosphatase activity
I927_06795	COG0235	Class ii aldolase
I927_06800	COG3623	hexulose-6-phosphate isomerase
I927_06805	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
I927_06830	COG1129	ABC transporter
I927_06835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I927_06840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
I927_06845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
I927_06850	COG2731	YhcH YjgK YiaL family protein
I927_06860	COG1414	Transcriptional regulator
I927_06870	COG0477	Major facilitator Superfamily
I927_06880	COG0351	phosphomethylpyrimidine kinase
I927_06890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I927_06895	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
I927_06900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I927_06905	COG1116	anion transmembrane transporter activity
I927_06920	COG0551	DNA topoisomerase type I activity
I927_06935	COG1070	Carbohydrate kinase
I927_06940	COG2390	Transcriptional regulator
I927_06945	COG1129	ABC transporter
I927_06985	COG0583	DNA-binding transcription factor activity
I927_06995	COG3956	TIGRFAM MazG family protein
I927_07015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I927_07030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I927_07035	COG2364	Membrane
I927_07040	COG0859	PFAM glycosyl transferase family 9
I927_07065	COG3069	C4-dicarboxylate transmembrane transporter activity
I927_07070	COG1473	amidohydrolase
I927_07075	COG1132	(ABC) transporter
I927_07080	COG0859	PFAM glycosyl transferase family 9
I927_07095	COG1519	Transferase
I927_07100	COG0463	Glycosyl transferase, family 2
I927_07115	COG1120	ATPase activity
I927_07120	COG0500	methyltransferase
I927_07130	COG0456	acetyltransferase
I927_07140	COG0762	integral membrane protein
I927_07150	COG3171	Protein conserved in bacteria
I927_07160	COG3038	cytochrome b561
I927_07165	COG1194	a g-specific adenine glycosylase
I927_07185	COG3056	Lipoprotein
I927_07190	COG0271	Belongs to the BolA IbaG family
I927_07195	COG1879	ABC-type sugar transport system periplasmic component
I927_07200	COG1129	ABC transporter
I927_07205	COG1172	Belongs to the binding-protein-dependent transport system permease family
I927_07240	COG1477	protein flavinylation
I927_07255	COG1230	cation diffusion facilitator family transporter
I927_07260	COG2271	Major facilitator Superfamily
I927_07270	COG2197	response regulator
I927_07275	COG2271	Major facilitator Superfamily
I927_07285	COG1349	DNA-binding transcription factor activity
I927_07290	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
I927_07295	COG1070	Carbohydrate kinase
I927_07300	COG4154	Belongs to the RbsD FucU family
I927_07305	COG0235	Class ii aldolase
I927_07310	COG1129	ABC transporter
I927_07315	COG1172	Belongs to the binding-protein-dependent transport system permease family
I927_07320	COG1879	ABC-type sugar transport system periplasmic component
I927_07325	COG1012	belongs to the aldehyde dehydrogenase family
I927_07335	COG1349	DNA-binding transcription factor activity
I927_07340	COG1309	transcriptional regulator
I927_07345	COG0583	DNA-binding transcription factor activity
I927_07350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
I927_07350	COG0678	peroxiredoxin activity
I927_07360	COG0545	Peptidyl-prolyl cis-trans isomerase
I927_07365	COG2964	Protein conserved in bacteria
I927_07380	COG2168	tRNA wobble position uridine thiolation
I927_07405	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I927_07425	COG1929	Belongs to the glycerate kinase type-1 family
I927_07430	COG2610	gluconate transmembrane transporter activity
I927_07465	COG3068	Protein conserved in bacteria
I927_07505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I927_07510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I927_07515	COG0006	proline dipeptidase activity
I927_07530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
I927_07565	COG1737	Transcriptional regulator
I927_07570	COG2731	YhcH YjgK YiaL family protein
I927_07605	COG4232	protein-disulfide reductase activity
I927_07635	COG1011	Hydrolase
I927_07650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I927_07670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I927_07680	COG0805	protein transport
I927_07725	COG1368	sulfuric ester hydrolase activity
I927_07730	COG3119	arylsulfatase activity
I927_07750	COG0641	radical SAM
I927_07755	COG1253	flavin adenine dinucleotide binding
I927_07765	COG0084	hydrolase, TatD family'
I927_07770	COG0470	DNA polymerase III
I927_07780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I927_07785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I927_07795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I927_07815	COG1555	photosystem II stabilization
I927_07840	COG0196	riboflavin kinase activity
I927_07845	COG0728	peptidoglycan biosynthetic process
I927_07860	COG0560	Phosphoserine phosphatase
I927_07875	COG0582	viral genome integration into host DNA
I927_07925	COG0582	viral genome integration into host DNA
I927_07945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I927_07965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
I927_07975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
I927_07995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I927_08000	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
I927_08015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I927_08020	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
I927_08025	COG4972	Pilus assembly protein
I927_08045	COG4796	Type ii and iii secretion system protein
I927_08060	COG0338	D12 class N6 adenine-specific DNA methyltransferase
I927_08065	COG4701	Protein of unknown function (DUF721)
I927_08085	COG0494	nUDIX hydrolase
I927_08095	COG1466	dna polymerase III delta subunit
I927_08100	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
I927_08120	COG2608	mercury ion transmembrane transporter activity
I927_08130	COG1305	Transglutaminase-like
I927_08145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I927_08225	COG2226	methyltransferase
I927_08235	COG0814	amino acid
I927_08245	COG4783	chaperone-mediated protein folding
I927_08260	COG0848	biopolymer transport protein
I927_08265	COG0811	peptide transport
I927_08270	COG4536	flavin adenine dinucleotide binding
I927_08275	COG4137	Cytochrome C assembly protein
I927_08280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I927_08330	COG3739	integral membrane protein
I927_08340	COG1720	tRNA m6t6A37 methyltransferase activity
I927_08345	COG1575	Belongs to the MenA family. Type 1 subfamily
I927_08355	COG0471	metal ion transport
I927_08380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
I927_08390	COG0592	DNA-directed DNA polymerase activity
I927_08400	COG2226	methyltransferase
I927_08425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I927_08495	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
I927_08500	COG1216	Glycosyl transferase, family 2
I927_08505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I927_08510	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
I927_08515	COG1309	transcriptional regulator
I927_08520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I927_08525	COG1956	GAF domain-containing protein
I927_08530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I927_08540	COG1393	Belongs to the ArsC family
I927_08545	COG3036	rescue of stalled ribosome
I927_08600	COG4785	May be involved in cell division
I927_08605	COG0513	Belongs to the DEAD box helicase family
I927_08615	COG3842	ATPase activity
I927_08620	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
I927_08625	COG0725	ABC transporter, periplasmic molybdate-binding protein
I927_08645	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
I927_08650	COG1027	Aspartate ammonia-lyase
I927_08675	COG4545	Glutaredoxin-related protein
I927_08685	COG4325	translation initiation factor activity
I927_08710	COG0511	ligase activity, forming carbon-carbon bonds
I927_08715	COG0439	Biotin carboxylase
I927_08720	COG3924	membrane
I927_08725	COG4145	pantothenate transmembrane transporter activity
I927_08780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I927_08785	COG4558	Periplasmic binding protein
I927_08805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I927_08820	COG4178	(ABC) transporter
I927_08830	COG3691	Protein conserved in bacteria
I927_08840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I927_08850	COG0861	Integral membrane protein TerC family
I927_08855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I927_08855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I927_08860	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
I927_08865	COG3722	fumarate hydratase activity
I927_08880	COG5645	(Lipo)protein
I927_08885	COG0210	DNA helicase
I927_08895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I927_08905	COG1238	metal cluster binding
I927_08920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I927_08935	COG0697	spore germination
I927_08945	COG0561	phosphatase activity
I927_08950	COG1702	phosphate starvation-inducible protein PhoH
I927_08965	COG1444	tRNA N-acetyltransferase activity
I927_08975	COG2194	sulfuric ester hydrolase activity
I927_08980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
I927_08985	COG4211	Belongs to the binding-protein-dependent transport system permease family
I927_08995	COG1879	ABC-type sugar transport system periplasmic component
I927_09000	COG1609	Transcriptional regulator
I927_09005	COG1085	galactose-1-phosphate uridylyltransferase
I927_09015	COG2017	converts alpha-aldose to the beta-anomer
I927_09030	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
I927_09035	COG1088	dTDP-glucose 4,6-dehydratase activity
I927_09060	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
I927_09070	COG1393	Belongs to the ArsC family
I927_09080	COG1876	peptidase activity
I927_09095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
I927_09110	COG1596	polysaccharide export
I927_09120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I927_09140	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
I927_09155	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
I927_09165	COG1086	Polysaccharide biosynthesis protein
I927_09185	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
I927_09190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I927_09215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I927_09225	COG0626	cystathionine gamma-synthase activity
I927_09245	COG1530	ribonuclease E activity
I927_09255	COG2056	Na+-H+ antiporter family
I927_09265	COG0346	lactoylglutathione lyase activity
I927_09280	COG1755	Isoprenylcysteine carboxyl methyltransferase
I927_09295	COG0494	nUDIX hydrolase
I927_09330	COG1271	oxidase subunit
I927_09335	COG1294	oxidase, subunit
I927_09350	COG0824	Thioesterase
I927_09355	COG0811	peptide transport
I927_09360	COG0848	biopolymer transport protein
I927_09365	COG3064	Membrane
I927_09380	COG2165	general secretion pathway protein
I927_09385	COG4795	General secretion pathway protein
I927_09405	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
I927_09410	COG0456	acetyltransferase
I927_09415	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
I927_09435	COG1840	ABC-type Fe3 transport system, periplasmic component
I927_09440	COG1840	ABC-type Fe3 transport system, periplasmic component
I927_09445	COG1840	ABC-type Fe3 transport system, periplasmic component
I927_09470	COG0659	secondary active sulfate transmembrane transporter activity
I927_09475	COG0800	Aldolase
I927_09490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I927_09495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I927_09500	COG0084	hydrolase, TatD family'
I927_09515	COG1328	CTP reductase activity
I927_09515	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
I927_09520	COG1858	cytochrome C peroxidase
I927_09530	COG0527	aspartate kinase activity
I927_09540	COG2860	membrane
I927_09550	COG3069	C4-dicarboxylate transmembrane transporter activity
I927_09570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
I927_09575	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
I927_09580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
I927_09585	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
I927_09590	COG1022	Amp-dependent synthetase and ligase
I927_09600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I927_09620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I927_09655	COG0748	coenzyme F420 binding
I927_09675	COG0489	protein tyrosine kinase activity
I927_09720	COG1518	maintenance of DNA repeat elements
I927_09730	COG0784	Response regulator, receiver
I927_09730	COG2198	Histidine kinase
I927_09730	COG5002	protein histidine kinase activity
I927_09745	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
I927_09750	COG1959	2 iron, 2 sulfur cluster binding
I927_09760	COG0822	iron-sulfur transferase activity
I927_09765	COG0316	Belongs to the HesB IscA family
I927_09780	COG0633	Ferredoxin
I927_09795	COG0741	lytic transglycosylase activity
I927_09800	COG2350	Protein conserved in bacteria
I927_09805	COG1607	acyl-coa hydrolase
I927_09825	COG0497	DNA recombination
I927_09840	COG1823	symporter activity
I927_09845	COG4771	TonB-dependent receptor
I927_09845	COG1629	transport
I927_09850	COG4771	TonB-dependent receptor
I927_09850	COG1629	transport
I927_09860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I927_09870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I927_09875	COG1530	ribonuclease E activity
I927_09890	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
I927_09895	COG0142	geranyltranstransferase activity
I927_09920	COG0697	spore germination
I927_09930	COG0735	belongs to the Fur family
I927_09935	COG0716	FMN binding
I927_09945	COG0596	Alpha beta hydrolase
I927_09950	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
I927_09965	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
I927_09965	COG3264	Mechanosensitive ion channel
I927_09975	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
I927_09980	COG0730	response to heat
I927_09985	COG1560	Kdo2-lipid A biosynthetic process
I927_10010	COG0251	oxidation-reduction process
I927_10025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I927_10030	COG0187	DNA topoisomerase II activity
I927_10035	COG0019	diaminopimelate decarboxylase activity
I927_10050	COG4797	methyltransferase
I927_10050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
I927_10060	COG4143	(ABC) transporter
I927_10065	COG1178	ABC-type Fe3 transport system permease component
I927_10080	COG0733	neurotransmitter:sodium symporter activity
I927_10085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
I927_10140	COG1289	transmembrane transporter activity
I927_10145	COG3304	Inner membrane component domain
I927_10165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I927_10170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I927_10175	COG1121	(ABC) transporter
I927_10185	COG2920	part of a sulfur-relay system
I927_10200	COG2864	formate dehydrogenase
I927_10205	COG0437	4 iron, 4 sulfur cluster binding
I927_10210	COG0243	molybdopterin cofactor binding
I927_10210	COG3383	formate dehydrogenase (NAD+) activity
I927_10215	COG0243	molybdopterin cofactor binding
I927_10215	COG3383	formate dehydrogenase (NAD+) activity
I927_10225	COG0210	DNA helicase
I927_10270	COG0583	DNA-binding transcription factor activity
I927_10275	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
I927_10280	COG1687	branched-chain amino acid
I927_10290	COG0488	(ABC) transporter
I927_10295	COG3683	transport system, periplasmic component
I927_10300	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
I927_10320	COG5002	protein histidine kinase activity
I927_10325	COG0745	RESPONSE REGULATOR receiver
I927_10355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
I927_10360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
I927_10370	COG2062	phosphohistidine phosphatase, SixA
I927_10400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I927_10405	COG1136	(ABC) transporter
I927_10405	COG0577	efflux transmembrane transporter activity
I927_10415	COG1136	(ABC) transporter
I927_10415	COG0577	efflux transmembrane transporter activity
I927_10430	COG0672	)-iron permease
I927_10440	COG2837	iron assimilation
I927_10445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I927_10460	COG0024	Methionine aminopeptidase