locus-tag	class	description
PB20LOC_000200	COG4104	PAAR repeat-containing protein
PB20LOC_000200	COG3209	COG3209 Rhs family protein
PB20LOC_000215	COG4104	PAAR repeat-containing protein
PB20LOC_000215	COG3209	COG3209 Rhs family protein
PB20LOC_000240	COG1979	alcohol dehydrogenase
PB20LOC_000245	COG0778	Nitroreductase
PB20LOC_000250	COG2207	Transcriptional regulator
PB20LOC_000255	COG0586	Pfam SNARE associated Golgi protein
PB20LOC_000275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PB20LOC_000285	COG0848	biopolymer transport protein
PB20LOC_000325	COG1203	CRISPR-associated helicase, Cas3
PB20LOC_000345	COG1857	crispr-associated protein
PB20LOC_000360	COG1518	maintenance of DNA repeat elements
PB20LOC_000365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PB20LOC_000380	COG4680	protein conserved in bacteria
PB20LOC_000385	COG5499	transcription regulator containing HTH domain
PB20LOC_000395	COG0076	glutamate decarboxylase activity
PB20LOC_000400	COG2814	Major facilitator Superfamily
PB20LOC_000410	COG3787	Belongs to the UPF0306 family
PB20LOC_000415	COG0702	epimerase
PB20LOC_000420	COG0602	queuosine metabolic process
PB20LOC_000425	COG1328	CTP reductase activity
PB20LOC_000435	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
PB20LOC_000440	COG0540	Belongs to the ATCase OTCase family
PB20LOC_000445	COG2731	YhcH YjgK YiaL family protein
PB20LOC_000460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PB20LOC_000480	COG0501	Belongs to the peptidase M48B family
PB20LOC_000485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PB20LOC_000490	COG0840	transmembrane signaling receptor activity
PB20LOC_000495	COG2831	hemolysin activation secretion protein
PB20LOC_000500	COG3210	domain, Protein
PB20LOC_000525	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
PB20LOC_000545	COG0525	valine-tRNA ligase activity
PB20LOC_000550	COG2927	DNA polymerase III (CHI subunit)
PB20LOC_000555	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PB20LOC_000560	COG0795	lipopolysaccharide-transporting ATPase activity
PB20LOC_000565	COG0795	lipopolysaccharide-transporting ATPase activity
PB20LOC_000575	COG0582	viral genome integration into host DNA
PB20LOC_000655	COG3596	GTP binding
PB20LOC_000675	COG2003	Belongs to the UPF0758 family
PB20LOC_000705	COG0529	Catalyzes the synthesis of activated sulfate
PB20LOC_000705	COG2046	Belongs to the sulfate adenylyltransferase family
PB20LOC_000760	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PB20LOC_000770	COG1136	(ABC) transporter
PB20LOC_000800	COG2304	oxidoreductase activity
PB20LOC_000805	COG2850	peptidyl-arginine hydroxylation
PB20LOC_000825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PB20LOC_000845	COG0583	DNA-binding transcription factor activity
PB20LOC_000870	COG4650	regulator
PB20LOC_000875	COG1690	Belongs to the RtcB family
PB20LOC_000880	COG3541	Predicted nucleotidyltransferase
PB20LOC_000900	COG0840	transmembrane signaling receptor activity
PB20LOC_000910	COG0840	transmembrane signaling receptor activity
PB20LOC_000915	COG3254	rhamnose metabolic process
PB20LOC_000920	COG0235	Class ii aldolase
PB20LOC_000925	COG4806	L-rhamnose isomerase
PB20LOC_000930	COG1070	Carbohydrate kinase
PB20LOC_000935	COG1917	Cupin 2, conserved barrel domain protein
PB20LOC_000935	COG2169	Transcriptional regulator
PB20LOC_000940	COG1917	Cupin 2, conserved barrel domain protein
PB20LOC_000940	COG4977	sequence-specific DNA binding
PB20LOC_000945	COG4115	mRNA cleavage
PB20LOC_000950	COG2161	toxin-antitoxin pair type II binding
PB20LOC_000960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB20LOC_000965	COG0601	transmembrane transport
PB20LOC_000970	COG0747	negative chemotaxis
PB20LOC_000975	COG3477	response to acidic pH
PB20LOC_000990	COG2862	Uncharacterized protein family, UPF0114
PB20LOC_000995	COG2130	NADP-dependent
PB20LOC_001115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PB20LOC_001120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PB20LOC_001125	COG0006	proline dipeptidase activity
PB20LOC_001130	COG3079	Belongs to the UPF0149 family
PB20LOC_001135	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PB20LOC_001145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PB20LOC_001160	COG0560	Phosphoserine phosphatase
PB20LOC_001165	COG3726	membrane protein affecting hemolysin expression
PB20LOC_001170	COG3620	sequence-specific DNA binding
PB20LOC_001175	COG3550	peptidyl-serine autophosphorylation
PB20LOC_001180	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PB20LOC_001185	COG2823	Periplasmic or secreted lipoprotein
PB20LOC_001190	COG5487	UPF0391 membrane protein
PB20LOC_001200	COG0084	hydrolase, TatD family'
PB20LOC_001205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PB20LOC_001215	COG4771	TonB-dependent receptor
PB20LOC_001225	COG1169	isochorismate synthase
PB20LOC_001230	COG1021	2,3-dihydroxybenzoate-AMP ligase
PB20LOC_001235	COG1028	Short-chain dehydrogenase reductase Sdr
PB20LOC_001280	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
PB20LOC_001280	COG0028	Belongs to the TPP enzyme family
PB20LOC_001285	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PB20LOC_001290	COG3624	Phosphonate C-P lyase system protein PhnG
PB20LOC_001295	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
PB20LOC_001300	COG3626	phosphonate metabolism
PB20LOC_001305	COG3627	carbon phosphorus lyase activity
PB20LOC_001310	COG4107	phosphonate C-P lyase system protein PhnK
PB20LOC_001315	COG4778	phosphonate C-P lyase system protein PhnL
PB20LOC_001320	COG3454	Phosphonate metabolism
PB20LOC_001325	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
PB20LOC_001330	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PB20LOC_001370	COG0297	glycogen (starch) synthase activity
PB20LOC_001375	COG0438	transferase activity, transferring glycosyl groups
PB20LOC_001390	COG1045	serine acetyltransferase
PB20LOC_001410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PB20LOC_001420	COG2226	methyltransferase
PB20LOC_001455	COG1309	transcriptional regulator
PB20LOC_001460	COG4232	protein-disulfide reductase activity
PB20LOC_001465	COG1324	tolerance protein
PB20LOC_001470	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PB20LOC_001485	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PB20LOC_001495	COG3161	chorismate lyase activity
PB20LOC_001500	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PB20LOC_001505	COG2937	Belongs to the GPAT DAPAT family
PB20LOC_001510	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PB20LOC_001520	COG0735	belongs to the Fur family
PB20LOC_001525	COG1741	Belongs to the pirin family
PB20LOC_001530	COG0583	DNA-binding transcription factor activity
PB20LOC_001535	COG0435	Glutathione S-transferase
PB20LOC_001540	COG2259	Doxx family
PB20LOC_001550	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
PB20LOC_001555	COG4575	ribosome binding
PB20LOC_001565	COG0586	Pfam SNARE associated Golgi protein
PB20LOC_001575	COG2271	Major facilitator Superfamily
PB20LOC_001580	COG1904	glucuronate isomerase
PB20LOC_001585	COG0246	Mannitol dehydrogenase
PB20LOC_001590	COG2721	sulfolactate sulfo-lyase activity
PB20LOC_001600	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PB20LOC_001605	COG0861	Integral membrane protein TerC family
PB20LOC_001610	COG0673	inositol 2-dehydrogenase activity
PB20LOC_001615	COG2813	Specifically methylates the guanine in position
PB20LOC_001620	COG1902	pentaerythritol trinitrate reductase activity
PB20LOC_001620	COG0446	pyridine nucleotide-disulphide oxidoreductase
PB20LOC_001630	COG3678	ATP-independent chaperone mediated protein folding
PB20LOC_001635	COG2199	diguanylate cyclase activity
PB20LOC_001660	COG3119	arylsulfatase activity
PB20LOC_001665	COG0641	radical SAM
PB20LOC_001670	COG3408	Glycogen debranching enzyme
PB20LOC_001670	COG3119	arylsulfatase activity
PB20LOC_001680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PB20LOC_001685	COG1554	hydrolase, family 65, central catalytic
PB20LOC_001690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB20LOC_001690	COG1263	PTS System
PB20LOC_001695	COG1609	Transcriptional regulator
PB20LOC_001705	COG0243	molybdopterin cofactor binding
PB20LOC_001715	COG0583	DNA-binding transcription factor activity
PB20LOC_001720	COG2188	Transcriptional regulator
PB20LOC_001725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PB20LOC_001730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB20LOC_001755	COG3663	DNA glycosylase
PB20LOC_001765	COG0358	DNA primase activity
PB20LOC_001770	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PB20LOC_001775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PB20LOC_001780	COG1438	arginine binding
PB20LOC_001785	COG0039	L-malate dehydrogenase activity
PB20LOC_001790	COG3423	Transcriptional regulator
PB20LOC_001805	COG0142	geranyltranstransferase activity
PB20LOC_001810	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PB20LOC_001815	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PB20LOC_001820	COG0697	spore germination
PB20LOC_001825	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PB20LOC_001830	COG2027	D-alanyl-D-alanine carboxypeptidase
PB20LOC_001840	COG1534	Rna-binding protein
PB20LOC_001845	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PB20LOC_001850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PB20LOC_001855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PB20LOC_001860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PB20LOC_001865	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PB20LOC_001880	COG0779	Required for maturation of 30S ribosomal subunits
PB20LOC_001890	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PB20LOC_001895	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PB20LOC_001900	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PB20LOC_001905	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PB20LOC_001910	COG1185	polyribonucleotide nucleotidyltransferase activity
PB20LOC_001925	COG0513	Belongs to the DEAD box helicase family
PB20LOC_001930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PB20LOC_001935	COG0826	peptidase U32
PB20LOC_001940	COG0826	peptidase U32
PB20LOC_001945	COG3154	lipid carrier protein
PB20LOC_001950	COG3153	acetyltransferase
PB20LOC_001955	COG2827	Endonuclease containing a URI domain
PB20LOC_001960	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PB20LOC_001965	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PB20LOC_001970	COG0813	purine-nucleoside phosphorylase activity
PB20LOC_001990	COG0456	acetyltransferase
PB20LOC_001995	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
PB20LOC_002000	COG2813	Specifically methylates the guanine in position
PB20LOC_002005	COG0656	L-ascorbic acid biosynthetic process
PB20LOC_002050	COG1454	alcohol dehydrogenase
PB20LOC_002055	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PB20LOC_002060	COG0509	glycine decarboxylation via glycine cleavage system
PB20LOC_002065	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PB20LOC_002065	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PB20LOC_002070	COG1175	transmembrane transport
PB20LOC_002080	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PB20LOC_002085	COG3842	ATPase activity
PB20LOC_002090	COG1653	transport
PB20LOC_002095	COG2211	Major facilitator Superfamily
PB20LOC_002115	COG1272	protein, Hemolysin III
PB20LOC_002120	COG0354	folic acid binding
PB20LOC_002125	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PB20LOC_002135	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PB20LOC_002145	COG0716	FMN binding
PB20LOC_002150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PB20LOC_002155	COG2011	ABC-type metal ion transport system permease component
PB20LOC_002160	COG1464	Belongs to the NlpA lipoprotein family
PB20LOC_002165	COG0477	Major facilitator Superfamily
PB20LOC_002170	COG4974	Belongs to the 'phage' integrase family
PB20LOC_002175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PB20LOC_002180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PB20LOC_002190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PB20LOC_002215	COG1560	Kdo2-lipid A biosynthetic process
PB20LOC_002220	COG2252	PERMEase
PB20LOC_002225	COG0025	NhaP-type Na H and K H
PB20LOC_002235	COG3850	Histidine kinase
PB20LOC_002235	COG5002	protein histidine kinase activity
PB20LOC_002255	COG4964	Belongs to the GSP D family
PB20LOC_002335	COG5464	transposase or invertase
PB20LOC_002340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PB20LOC_002345	COG3162	membrane
PB20LOC_002350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PB20LOC_002360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB20LOC_002360	COG3711	transcriptional antiterminator
PB20LOC_002375	COG3964	amidohydrolase
PB20LOC_002420	COG0246	Mannitol dehydrogenase
PB20LOC_002425	COG2873	o-acetylhomoserine
PB20LOC_002430	COG1376	ErfK ybiS ycfS ynhG family protein
PB20LOC_002435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PB20LOC_002440	COG3038	cytochrome b561
PB20LOC_002445	COG0674	pyruvate-flavodoxin oxidoreductase activity
PB20LOC_002445	COG1013	pyruvate-flavodoxin oxidoreductase activity
PB20LOC_002445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PB20LOC_002445	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PB20LOC_002460	COG2211	Major facilitator Superfamily
PB20LOC_002470	COG1280	lysine exporter protein (LysE YggA)
PB20LOC_002565	COG0582	viral genome integration into host DNA
PB20LOC_002575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PB20LOC_002580	COG2867	negative regulation of translational initiation
PB20LOC_002585	COG2914	Belongs to the UPF0125 (RnfH) family
PB20LOC_002595	COG0497	DNA recombination
PB20LOC_002600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PB20LOC_002605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PB20LOC_002610	COG1914	H( )-stimulated, divalent metal cation uptake system
PB20LOC_002630	COG1942	4-Oxalocrotonate Tautomerase
PB20LOC_002635	COG0494	nUDIX hydrolase
PB20LOC_002665	COG1609	Transcriptional regulator
PB20LOC_002670	COG3711	transcriptional antiterminator
PB20LOC_002675	COG2723	6-phospho-beta-galactosidase activity
PB20LOC_002680	COG2190	(PTS) system
PB20LOC_002680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB20LOC_002680	COG1263	PTS System
PB20LOC_002685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PB20LOC_002690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PB20LOC_002695	COG0698	ribose 5-phosphate isomerase
PB20LOC_002710	COG3395	kinase activity
PB20LOC_002720	COG0149	triose-phosphate isomerase activity
PB20LOC_002725	COG2390	Transcriptional regulator
PB20LOC_002735	COG0814	amino acid
PB20LOC_002740	COG1671	Belongs to the UPF0178 family
PB20LOC_002745	COG0408	coproporphyrinogen oxidase activity
PB20LOC_002750	COG0456	acetyltransferase
PB20LOC_002765	COG4771	TonB-dependent receptor
PB20LOC_002770	COG0612	Peptidase, M16
PB20LOC_002775	COG4178	(ABC) transporter
PB20LOC_002785	COG2837	iron assimilation
PB20LOC_002790	COG4150	thiosulfate binding
PB20LOC_002795	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PB20LOC_002800	COG4208	sulfate ABC transporter
PB20LOC_002805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PB20LOC_002810	COG1136	(ABC) transporter
PB20LOC_002810	COG0577	efflux transmembrane transporter activity
PB20LOC_002815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PB20LOC_002820	COG0745	RESPONSE REGULATOR receiver
PB20LOC_002825	COG2205	protein histidine kinase activity
PB20LOC_002830	COG2190	(PTS) system
PB20LOC_002840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB20LOC_002850	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
PB20LOC_002855	COG3115	cell septum assembly
PB20LOC_002860	COG0531	amino acid
PB20LOC_002870	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PB20LOC_002880	COG0446	pyridine nucleotide-disulphide oxidoreductase
PB20LOC_002885	COG1773	rubredoxin
PB20LOC_002885	COG0426	domain, Protein
PB20LOC_002890	COG3604	Transcriptional regulator
PB20LOC_002895	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
PB20LOC_002895	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
PB20LOC_002900	COG0583	DNA-binding transcription factor activity
PB20LOC_002915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PB20LOC_002915	COG2169	Transcriptional regulator
PB20LOC_002930	COG3976	FMN-binding domain protein
PB20LOC_002930	COG1053	succinate dehydrogenase
PB20LOC_002930	COG0431	NADPH-dependent FMN reductase
PB20LOC_002935	COG0477	Major facilitator Superfamily
PB20LOC_002940	COG3301	Polysulphide reductase, NrfD
PB20LOC_002945	COG0437	4 iron, 4 sulfur cluster binding
PB20LOC_002955	COG0583	DNA-binding transcription factor activity
PB20LOC_002960	COG4948	Mandelate Racemase Muconate Lactonizing
PB20LOC_002965	COG1063	alcohol dehydrogenase
PB20LOC_002970	COG0477	Major facilitator Superfamily
PB20LOC_002975	COG0246	Mannitol dehydrogenase
PB20LOC_002980	COG1802	Transcriptional regulator
PB20LOC_002990	COG2814	Major facilitator Superfamily
PB20LOC_003020	COG0673	inositol 2-dehydrogenase activity
PB20LOC_003025	COG2897	thiosulfate sulfurtransferase activity
PB20LOC_003030	COG1126	abc transporter atp-binding protein
PB20LOC_003035	COG0765	amino acid transport
PB20LOC_003040	COG0765	amino acid transport
PB20LOC_003045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB20LOC_003055	COG0626	cystathionine gamma-synthase activity
PB20LOC_003060	COG2843	Capsule synthesis protein
PB20LOC_003065	COG4773	Receptor
PB20LOC_003080	COG3121	Chaperone
PB20LOC_003185	COG3829	transcription factor binding
PB20LOC_003310	COG2999	glutathione oxidoreductase activity
PB20LOC_003315	COG0583	DNA-binding transcription factor activity
PB20LOC_003320	COG2814	Major facilitator Superfamily
PB20LOC_003345	COG1546	Belongs to the CinA family
PB20LOC_003350	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PB20LOC_003355	COG2137	regulation of response to DNA damage stimulus
PB20LOC_003360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PB20LOC_003365	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PB20LOC_003390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PB20LOC_003395	COG1238	metal cluster binding
PB20LOC_003400	COG2918	glutathione biosynthetic process
PB20LOC_003405	COG1854	S-ribosylhomocysteine lyase activity
PB20LOC_003410	COG4137	Cytochrome C assembly protein
PB20LOC_003415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PB20LOC_003420	COG0228	four-way junction DNA binding
PB20LOC_003425	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PB20LOC_003430	COG0336	Belongs to the RNA methyltransferase TrmD family
PB20LOC_003435	COG0335	large ribosomal subunit rRNA binding
PB20LOC_003440	COG2264	protein methyltransferase activity
PB20LOC_003450	COG3279	Response regulator of the LytR AlgR family
PB20LOC_003455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PB20LOC_003460	COG1605	Chorismate mutase
PB20LOC_003460	COG0287	Prephenate dehydrogenase
PB20LOC_003465	COG0077	Prephenate dehydratase
PB20LOC_003465	COG1605	Chorismate mutase
PB20LOC_003470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PB20LOC_003475	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PB20LOC_003480	COG0564	pseudouridine synthase activity
PB20LOC_003490	COG0542	response to heat
PB20LOC_003525	COG3021	interspecies interaction between organisms
PB20LOC_003530	COG1388	LysM domain
PB20LOC_003530	COG0741	lytic transglycosylase activity
PB20LOC_003535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PB20LOC_003540	COG2226	methyltransferase
PB20LOC_003545	COG0328	RNA-DNA hybrid ribonuclease activity
PB20LOC_003560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PB20LOC_003570	COG1780	Probably involved in ribonucleotide reductase function
PB20LOC_003575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PB20LOC_003590	COG3842	ATPase activity
PB20LOC_003605	COG0288	reversible hydration of carbon dioxide
PB20LOC_003610	COG1131	(ABC) transporter
PB20LOC_003615	COG0842	Transport permease protein
PB20LOC_003620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PB20LOC_003625	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PB20LOC_003630	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PB20LOC_003635	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PB20LOC_003645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PB20LOC_003655	COG1489	DNA binding
PB20LOC_003660	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PB20LOC_003665	COG1643	Atp-dependent helicase
PB20LOC_003670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PB20LOC_003675	COG1120	ATPase activity
PB20LOC_003680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PB20LOC_003685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB20LOC_003695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PB20LOC_003700	COG0625	glutathione transferase activity
PB20LOC_003705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PB20LOC_003710	COG0316	Belongs to the HesB IscA family
PB20LOC_003720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PB20LOC_003725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PB20LOC_003730	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PB20LOC_003735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PB20LOC_003740	COG3835	regulator
PB20LOC_003745	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PB20LOC_003755	COG4208	sulfate ABC transporter
PB20LOC_003760	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PB20LOC_003775	COG0667	Aldo Keto reductase
PB20LOC_003780	COG1902	pentaerythritol trinitrate reductase activity
PB20LOC_003810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PB20LOC_003815	COG2819	hydrolase of the alpha beta superfamily
PB20LOC_003830	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PB20LOC_003835	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
PB20LOC_003840	COG0513	Belongs to the DEAD box helicase family
PB20LOC_003845	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PB20LOC_003850	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PB20LOC_003865	COG3026	antisigma factor binding
PB20LOC_003870	COG3086	response to oxidative stress
PB20LOC_003875	COG0481	GTPase activity
PB20LOC_003885	COG0571	ribonuclease III activity
PB20LOC_003890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PB20LOC_003895	COG1381	Involved in DNA repair and RecF pathway recombination
PB20LOC_003900	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PB20LOC_003905	COG0736	holo-[acyl-carrier-protein] synthase activity
PB20LOC_003910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PB20LOC_003915	COG2200	EAL domain
PB20LOC_003925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PB20LOC_003950	COG2199	diguanylate cyclase activity
PB20LOC_003950	COG2200	EAL domain
PB20LOC_003950	COG3287	FIST C domain
PB20LOC_003960	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PB20LOC_003965	COG0560	Phosphoserine phosphatase
PB20LOC_003975	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PB20LOC_003980	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PB20LOC_003980	COG0047	phosphoribosylformylglycinamidine synthase activity
PB20LOC_003985	COG2205	protein histidine kinase activity
PB20LOC_003990	COG3170	Tfp pilus assembly protein FimV
PB20LOC_003995	COG2204	response regulator
PB20LOC_004000	COG0347	Belongs to the P(II) protein family
PB20LOC_004005	COG4677	pectinesterase activity
PB20LOC_004015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PB20LOC_004015	COG1017	nitric oxide dioxygenase activity
PB20LOC_004020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PB20LOC_004025	COG2814	Major facilitator Superfamily
PB20LOC_004030	COG3683	transport system, periplasmic component
PB20LOC_004035	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
PB20LOC_004045	COG0840	transmembrane signaling receptor activity
PB20LOC_004055	COG1120	ATPase activity
PB20LOC_004060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB20LOC_004070	COG0483	inositol monophosphate 1-phosphatase activity
PB20LOC_004075	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
PB20LOC_004080	COG1959	2 iron, 2 sulfur cluster binding
PB20LOC_004085	COG1104	cysteine desulfurase activity
PB20LOC_004090	COG0822	iron-sulfur transferase activity
PB20LOC_004095	COG0316	Belongs to the HesB IscA family
PB20LOC_004100	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PB20LOC_004105	COG0443	Heat shock 70 kDa protein
PB20LOC_004110	COG0633	Ferredoxin
PB20LOC_004120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PB20LOC_004130	COG2897	thiosulfate sulfurtransferase activity
PB20LOC_004140	COG0105	UTP biosynthetic process
PB20LOC_004145	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PB20LOC_004155	COG1426	Protein conserved in bacteria
PB20LOC_004160	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PB20LOC_004165	COG0124	histidyl-tRNA synthetase
PB20LOC_004170	COG2976	Protein conserved in bacteria
PB20LOC_004175	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PB20LOC_004180	COG1160	GTP binding
PB20LOC_004190	COG1645	bacterial-type flagellum-dependent swarming motility
PB20LOC_004205	COG1570	exodeoxyribonuclease VII activity
PB20LOC_004210	COG0516	GMP reductase activity
PB20LOC_004210	COG0517	IMP dehydrogenase activity
PB20LOC_004215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PB20LOC_004215	COG0519	Catalyzes the synthesis of GMP from XMP
PB20LOC_004230	COG0667	Aldo Keto reductase
PB20LOC_004250	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PB20LOC_004260	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PB20LOC_004305	COG1064	alcohol dehydrogenase
PB20LOC_004320	COG1064	alcohol dehydrogenase
PB20LOC_004330	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PB20LOC_004335	COG0066	3-isopropylmalate dehydratase activity
PB20LOC_004340	COG0179	Fumarylacetoacetate (FAA) hydrolase
PB20LOC_004345	COG3493	citrate carrier protein
PB20LOC_004350	COG0583	DNA-binding transcription factor activity
PB20LOC_004370	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PB20LOC_004375	COG0351	phosphomethylpyrimidine kinase
PB20LOC_004380	COG3223	Belongs to the PsiE family
PB20LOC_004385	COG1597	lipid kinase activity
PB20LOC_004390	COG0826	peptidase U32
PB20LOC_004395	COG0435	Glutathione S-transferase
PB20LOC_004405	COG0745	RESPONSE REGULATOR receiver
PB20LOC_004410	COG2205	protein histidine kinase activity
PB20LOC_004415	COG0477	Major facilitator Superfamily
PB20LOC_004420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PB20LOC_004425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PB20LOC_004430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PB20LOC_004435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PB20LOC_004445	COG0277	FAD linked oxidase domain protein
PB20LOC_004455	COG1874	Beta-galactosidase
PB20LOC_004460	COG3867	Arabinogalactan endo-beta-1,4-galactanase
PB20LOC_004465	COG3833	ABC-type maltose transport systems, permease component
PB20LOC_004470	COG1175	transmembrane transport
PB20LOC_004475	COG2182	Extracellular solute-binding protein
PB20LOC_004485	COG4580	involved in the transport of maltose and maltodextrins
PB20LOC_004490	COG1609	Transcriptional regulator
PB20LOC_004495	COG1085	galactose-1-phosphate uridylyltransferase
PB20LOC_004505	COG2239	Acts as a magnesium transporter
PB20LOC_004510	COG1846	Transcriptional regulator
PB20LOC_004515	COG1764	response to oxidative stress
PB20LOC_004535	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PB20LOC_004540	COG0573	inorganic phosphate transmembrane transporter activity
PB20LOC_004545	COG0581	inorganic phosphate transmembrane transporter activity
PB20LOC_004550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PB20LOC_004565	COG0814	amino acid
PB20LOC_004570	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PB20LOC_004575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PB20LOC_004580	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PB20LOC_004585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PB20LOC_004595	COG0215	cysteine-tRNA ligase activity
PB20LOC_004600	COG2501	S4 domain
PB20LOC_004605	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PB20LOC_004610	COG3706	GGDEF domain
PB20LOC_004610	COG4251	negative regulation of phosphorylation
PB20LOC_004610	COG5001	Diguanylate cyclase
PB20LOC_004610	COG2203	Gaf domain
PB20LOC_004615	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PB20LOC_004620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PB20LOC_004625	COG0463	Glycosyl transferase, family 2
PB20LOC_004630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PB20LOC_004630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PB20LOC_004635	COG0726	polysaccharide deacetylase
PB20LOC_004640	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PB20LOC_004645	COG2076	Multidrug Resistance protein
PB20LOC_004650	COG2076	Multidrug Resistance protein
PB20LOC_004655	COG3842	ATPase activity
PB20LOC_004685	COG1696	Membrane protein involved in D-alanine export
PB20LOC_004690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PB20LOC_004700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PB20LOC_004745	COG2801	Transposase and inactivated derivatives
PB20LOC_004765	COG0582	viral genome integration into host DNA
PB20LOC_004790	COG2003	Belongs to the UPF0758 family
PB20LOC_004810	COG2378	regulation of single-species biofilm formation
PB20LOC_004815	COG3596	GTP binding
PB20LOC_004875	COG0582	viral genome integration into host DNA
PB20LOC_004885	COG1511	domain protein
PB20LOC_004885	COG3264	Mechanosensitive ion channel
PB20LOC_004895	COG4948	Mandelate Racemase Muconate Lactonizing
PB20LOC_004900	COG0436	Aminotransferase
PB20LOC_004910	COG3266	domain, Protein
PB20LOC_004985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PB20LOC_004990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PB20LOC_004995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB20LOC_005000	COG1120	ATPase activity
PB20LOC_005010	COG0513	Belongs to the DEAD box helicase family
PB20LOC_005065	COG0579	oxidoreductase
PB20LOC_005070	COG0583	DNA-binding transcription factor activity
PB20LOC_005075	COG1028	Short-chain dehydrogenase reductase Sdr
PB20LOC_005080	COG2067	long-chain fatty acid transport protein
PB20LOC_005085	COG3691	Protein conserved in bacteria
PB20LOC_005090	COG0183	Belongs to the thiolase family
PB20LOC_005095	COG1250	3-hydroxyacyl-CoA dehydrogenase
PB20LOC_005095	COG1024	Enoyl-CoA hydratase
PB20LOC_005105	COG3188	usher protein
PB20LOC_005125	COG2062	phosphohistidine phosphatase, SixA
PB20LOC_005130	COG2840	Smr protein MutS2
PB20LOC_005135	COG2890	protein-(glutamine-N5) methyltransferase activity
PB20LOC_005140	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PB20LOC_005145	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
PB20LOC_005150	COG0730	response to heat
PB20LOC_005155	COG3101	peptidyl-lysine hydroxylation
PB20LOC_005165	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PB20LOC_005165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PB20LOC_005170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PB20LOC_005185	COG0697	spore germination
PB20LOC_005190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PB20LOC_005195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PB20LOC_005200	COG0101	tRNA pseudouridine synthase activity
PB20LOC_005205	COG0586	Pfam SNARE associated Golgi protein
PB20LOC_005210	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PB20LOC_005215	COG0285	dihydrofolate synthase activity
PB20LOC_005220	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
PB20LOC_005225	COG1286	toxin biosynthetic process
PB20LOC_005230	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PB20LOC_005235	COG0163	prenyltransferase activity
PB20LOC_005245	COG4215	(ABC) transporter
PB20LOC_005250	COG4160	amino acid transport
PB20LOC_005255	COG4598	ABC transporter
PB20LOC_005260	COG1090	epimerase
PB20LOC_005265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PB20LOC_005270	COG0625	glutathione transferase activity
PB20LOC_005275	COG0622	Phosphoesterase
PB20LOC_005280	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
PB20LOC_005285	COG3739	integral membrane protein
PB20LOC_005290	COG0857	belongs to the CobB CobQ family
PB20LOC_005290	COG0280	phosphate acetyltransferase
PB20LOC_005295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PB20LOC_005300	COG3092	negative regulation of chromosome organization
PB20LOC_005305	COG3013	Belongs to the UPF0304 family
PB20LOC_005310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PB20LOC_005315	COG0490	domain, Protein
PB20LOC_005315	COG0471	metal ion transport
PB20LOC_005320	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
PB20LOC_005325	COG0436	Aminotransferase
PB20LOC_005330	COG0583	DNA-binding transcription factor activity
PB20LOC_005335	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PB20LOC_005340	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PB20LOC_005345	COG0649	NAD binding
PB20LOC_005345	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PB20LOC_005350	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
PB20LOC_005355	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
PB20LOC_005365	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PB20LOC_005370	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PB20LOC_005375	COG0839	Belongs to the complex I subunit 6 family
PB20LOC_005380	COG0713	ATP synthesis coupled electron transport
PB20LOC_005385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PB20LOC_005390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PB20LOC_005395	COG1007	ATP synthesis coupled electron transport
PB20LOC_005400	COG4575	ribosome binding
PB20LOC_005405	COG0366	Alpha amylase catalytic
PB20LOC_005410	COG1263	PTS System
PB20LOC_005410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB20LOC_005420	COG2223	nitrite transmembrane transporter activity
PB20LOC_005430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PB20LOC_005445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB20LOC_005455	COG0488	(ABC) transporter
PB20LOC_005460	COG4771	TonB-dependent receptor
PB20LOC_005490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PB20LOC_005495	COG3058	Necessary for formate dehydrogenase activity
PB20LOC_005505	COG2149	membrane
PB20LOC_005510	COG1737	Transcriptional regulator
PB20LOC_005525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB20LOC_005525	COG2190	(PTS) system
PB20LOC_005525	COG1263	PTS System
PB20LOC_005530	COG0641	radical SAM
PB20LOC_005535	COG4890	Cyd operon protein YbgT
PB20LOC_005540	COG1294	oxidase, subunit
PB20LOC_005545	COG1271	oxidase subunit
PB20LOC_005560	COG3707	response regulator
PB20LOC_005565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PB20LOC_005575	COG1116	anion transmembrane transporter activity
PB20LOC_005580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PB20LOC_005580	COG2146	nitrite reductase [NAD(P)H] activity
PB20LOC_005585	COG0243	molybdopterin cofactor binding
PB20LOC_005590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PB20LOC_005590	COG1648	precorrin-2 dehydrogenase activity
PB20LOC_005595	COG5464	transposase or invertase
PB20LOC_005600	COG4807	Protein conserved in bacteria
PB20LOC_005605	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PB20LOC_005610	COG0640	Transcriptional regulator
PB20LOC_005615	COG1902	pentaerythritol trinitrate reductase activity
PB20LOC_005635	COG4948	Mandelate Racemase Muconate Lactonizing
PB20LOC_005640	COG0659	secondary active sulfate transmembrane transporter activity
PB20LOC_005645	COG0300	oxidoreductase activity
PB20LOC_005675	COG3228	Belongs to the MtfA family
PB20LOC_005705	COG1113	amino acid transport
PB20LOC_005725	COG2197	response regulator
PB20LOC_005730	COG0322	excinuclease ABC activity
PB20LOC_005735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PB20LOC_005755	COG0582	viral genome integration into host DNA
PB20LOC_005760	COG2815	serine threonine protein kinase
PB20LOC_005760	COG0515	serine threonine protein kinase
PB20LOC_005830	COG0582	viral genome integration into host DNA
PB20LOC_005840	COG2223	nitrite transmembrane transporter activity
PB20LOC_005845	COG3250	beta-galactosidase activity
PB20LOC_005850	COG1609	Transcriptional regulator
PB20LOC_005855	COG3842	ATPase activity
PB20LOC_005865	COG1840	ABC-type Fe3 transport system, periplasmic component
PB20LOC_005870	COG2271	Major facilitator Superfamily
PB20LOC_005885	COG1464	Belongs to the NlpA lipoprotein family
PB20LOC_005900	COG0583	DNA-binding transcription factor activity
PB20LOC_005905	COG1301	dicarboxylic acid transport
PB20LOC_005910	COG3383	formate dehydrogenase (NAD+) activity
PB20LOC_005920	COG0672	)-iron permease
PB20LOC_005935	COG1136	(ABC) transporter
PB20LOC_005935	COG0577	efflux transmembrane transporter activity
PB20LOC_005945	COG0577	efflux transmembrane transporter activity
PB20LOC_005945	COG1136	(ABC) transporter
PB20LOC_005950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PB20LOC_005955	COG0697	spore germination
PB20LOC_005970	COG1301	dicarboxylic acid transport
PB20LOC_005975	COG0371	Dehydrogenase
PB20LOC_005980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PB20LOC_005995	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PB20LOC_006005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PB20LOC_006015	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PB20LOC_006065	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PB20LOC_006090	COG1012	belongs to the aldehyde dehydrogenase family
PB20LOC_006095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PB20LOC_006100	COG0840	transmembrane signaling receptor activity
PB20LOC_006115	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PB20LOC_006120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB20LOC_006125	COG0747	negative chemotaxis
PB20LOC_006165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PB20LOC_006190	COG0784	Response regulator, receiver
PB20LOC_006190	COG0835	chemotaxis
PB20LOC_006200	COG3226	Transcriptional regulator
PB20LOC_006205	COG2814	Major facilitator Superfamily
PB20LOC_006210	COG0625	glutathione transferase activity
PB20LOC_006220	COG0640	Transcriptional regulator
PB20LOC_006235	COG3706	GGDEF domain
PB20LOC_006245	COG0840	transmembrane signaling receptor activity
PB20LOC_006275	COG0643	Histidine kinase
PB20LOC_006275	COG2198	Histidine kinase
PB20LOC_006280	COG0835	chemotaxis
PB20LOC_006285	COG0840	transmembrane signaling receptor activity
PB20LOC_006290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PB20LOC_006295	COG2201	protein-glutamate methylesterase activity
PB20LOC_006300	COG0745	RESPONSE REGULATOR receiver
PB20LOC_006310	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PB20LOC_006315	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PB20LOC_006325	COG3418	PFAM FlgN family protein
PB20LOC_006330	COG2747	anti-sigma28 factor FlgM
PB20LOC_006340	COG1815	bacterial-type flagellum-dependent cell motility
PB20LOC_006345	COG1558	bacterial-type flagellum-dependent cell motility
PB20LOC_006350	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PB20LOC_006355	COG1749	Flagellar hook protein flgE
PB20LOC_006360	COG4787	bacterial-type flagellum-dependent cell motility
PB20LOC_006370	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PB20LOC_006375	COG1706	bacterial-type flagellum-dependent cell motility
PB20LOC_006390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PB20LOC_006425	COG1580	Controls the rotational direction of flagella during chemotaxis
PB20LOC_006445	COG1317	bacterial-type flagellum organization
PB20LOC_006450	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PB20LOC_006460	COG1677	Flagellar hook-basal body complex protein FliE
PB20LOC_006475	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PB20LOC_006485	COG4797	methyltransferase
PB20LOC_006485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PB20LOC_006490	COG1191	sigma factor activity
PB20LOC_006500	COG1702	phosphate starvation-inducible protein PhoH
PB20LOC_006505	COG0582	viral genome integration into host DNA
PB20LOC_006515	COG3083	sulfuric ester hydrolase activity
PB20LOC_006520	COG3082	Protein of unknown function (DUF1414)
PB20LOC_006525	COG3081	Nucleoid-associated protein
PB20LOC_006535	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PB20LOC_006540	COG1061	Type III restriction enzyme res subunit
PB20LOC_006555	COG2814	Major facilitator Superfamily
PB20LOC_006565	COG4172	Belongs to the ABC transporter superfamily
PB20LOC_006570	COG4239	(ABC) transporter, permease
PB20LOC_006575	COG4174	ABC transporter (Permease)
PB20LOC_006580	COG4166	transmembrane transport
PB20LOC_006585	COG0791	NLP P60 protein
PB20LOC_006590	COG0671	phosphoesterase, PA-phosphatase related
PB20LOC_006595	COG0523	cobalamin synthesis protein
PB20LOC_006600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PB20LOC_006620	COG1105	Belongs to the carbohydrate kinase PfkB family
PB20LOC_006625	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PB20LOC_006625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PB20LOC_006625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PB20LOC_006630	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PB20LOC_006635	COG0583	DNA-binding transcription factor activity
PB20LOC_006640	COG0833	amino acid
PB20LOC_006645	COG4771	TonB-dependent receptor
PB20LOC_006650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PB20LOC_006655	COG1172	Belongs to the binding-protein-dependent transport system permease family
PB20LOC_006660	COG1129	ABC transporter
PB20LOC_006665	COG0371	Dehydrogenase
PB20LOC_006690	COG0583	DNA-binding transcription factor activity
PB20LOC_006695	COG0840	transmembrane signaling receptor activity
PB20LOC_006700	COG0302	gtp cyclohydrolase
PB20LOC_006705	COG2311	Membrane
PB20LOC_006710	COG2949	membrane
PB20LOC_006715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PB20LOC_006720	COG2133	pyrroloquinoline quinone binding
PB20LOC_006725	COG0625	glutathione transferase activity
PB20LOC_006730	COG1464	Belongs to the NlpA lipoprotein family
PB20LOC_006740	COG1686	Belongs to the peptidase S11 family
PB20LOC_006745	COG1349	DNA-binding transcription factor activity
PB20LOC_006750	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PB20LOC_006755	COG0569	domain protein
PB20LOC_006755	COG2985	domain, Protein
PB20LOC_006770	COG0778	Nitroreductase
PB20LOC_006775	COG0189	ligase activity
PB20LOC_006785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PB20LOC_006790	COG3842	ATPase activity
PB20LOC_006795	COG1176	ABC-type spermidine putrescine transport system, permease component I
PB20LOC_006800	COG1177	transmembrane transport
PB20LOC_006810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PB20LOC_006815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB20LOC_006820	COG4160	amino acid transport
PB20LOC_006825	COG4215	(ABC) transporter
PB20LOC_006830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB20LOC_006835	COG1126	abc transporter atp-binding protein
PB20LOC_006840	COG0393	Putative heavy-metal-binding
PB20LOC_006845	COG3023	N-Acetylmuramoyl-L-alanine amidase
PB20LOC_006850	COG0702	epimerase
PB20LOC_006855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PB20LOC_006860	COG1151	hydroxylamine reductase activity
PB20LOC_006865	COG2431	L-lysine efflux transmembrane transporter activity
PB20LOC_006870	COG3593	DNA synthesis involved in DNA repair
PB20LOC_006875	COG1278	Cold shock
PB20LOC_006880	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PB20LOC_006885	COG0542	response to heat
PB20LOC_006895	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PB20LOC_006900	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PB20LOC_006905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PB20LOC_006910	COG4988	ABC transporter
PB20LOC_006915	COG0492	ferredoxin-NADP+ reductase activity
PB20LOC_006925	COG1674	ftsk spoiiie
PB20LOC_006925	COG3107	peptidoglycan biosynthetic process
PB20LOC_006930	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PB20LOC_006935	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PB20LOC_006940	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PB20LOC_006945	COG0477	Major facilitator Superfamily
PB20LOC_006970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PB20LOC_006975	COG1882	Formate acetyltransferase
PB20LOC_006980	COG2116	formate transmembrane transporter activity
PB20LOC_006985	COG1944	ATP diphosphatase activity
PB20LOC_006990	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PB20LOC_006995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PB20LOC_007000	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PB20LOC_007005	COG0539	negative regulation of cytoplasmic translation
PB20LOC_007010	COG0776	regulation of translation
PB20LOC_007015	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PB20LOC_007015	COG0140	phosphoribosyl-ATP diphosphatase activity
PB20LOC_007020	COG0107	imidazoleglycerol-phosphate synthase activity
PB20LOC_007025	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PB20LOC_007030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PB20LOC_007035	COG0131	Imidazoleglycerol-phosphate dehydratase
PB20LOC_007035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PB20LOC_007040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PB20LOC_007045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PB20LOC_007050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PB20LOC_007060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PB20LOC_007085	COG0840	transmembrane signaling receptor activity
PB20LOC_007090	COG0840	transmembrane signaling receptor activity
PB20LOC_007095	COG4565	transcriptional regulatory protein
PB20LOC_007105	COG3493	citrate carrier protein
PB20LOC_007110	COG0179	Fumarylacetoacetate (FAA) hydrolase
PB20LOC_007115	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PB20LOC_007120	COG3052	prosthetic group binding
PB20LOC_007140	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
PB20LOC_007145	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PB20LOC_007155	COG0531	amino acid
PB20LOC_007160	COG2925	Exonuclease
PB20LOC_007165	COG4607	ABC-type enterochelin transport system periplasmic component
PB20LOC_007175	COG4605	iron ion homeostasis
PB20LOC_007180	COG4604	ABC transporter, ATP-binding protein
PB20LOC_007185	COG2926	Belongs to the UPF0265 family
PB20LOC_007190	COG2333	competence protein COMEC
PB20LOC_007190	COG0658	competence protein
PB20LOC_007195	COG1132	(ABC) transporter
PB20LOC_007200	COG1663	tetraacyldisaccharide 4'-kinase activity
PB20LOC_007205	COG2835	tetraacyldisaccharide 4'-kinase activity
PB20LOC_007210	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PB20LOC_007215	COG4733	cellulase activity
PB20LOC_007220	COG3173	Aminoglycoside phosphotransferase
PB20LOC_007225	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PB20LOC_007230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PB20LOC_007235	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
PB20LOC_007240	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
PB20LOC_007245	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PB20LOC_007250	COG2989	Protein conserved in bacteria
PB20LOC_007255	COG3108	Peptidase M15
PB20LOC_007260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PB20LOC_007265	COG1448	Aminotransferase
PB20LOC_007275	COG0017	Asparaginyl-tRNA synthetase
PB20LOC_007280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PB20LOC_007285	COG0308	aminopeptidase N
PB20LOC_007290	COG0167	dihydroorotate dehydrogenase activity
PB20LOC_007300	COG0633	Ferredoxin
PB20LOC_007300	COG3217	Mosc domain protein beta barrel domain protein
PB20LOC_007305	COG0116	Belongs to the methyltransferase superfamily
PB20LOC_007305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PB20LOC_007310	COG0488	(ABC) transporter
PB20LOC_007315	COG2995	paraquat-inducible protein a
PB20LOC_007320	COG3008	intermembrane lipid transfer
PB20LOC_007320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PB20LOC_007325	COG3009	Protein conserved in bacteria
PB20LOC_007330	COG3130	regulation of translation
PB20LOC_007335	COG0840	transmembrane signaling receptor activity
PB20LOC_007365	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PB20LOC_007370	COG3381	protein complex oligomerization
PB20LOC_007380	COG2999	glutathione oxidoreductase activity
PB20LOC_007385	COG0477	Major facilitator Superfamily
PB20LOC_007390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB20LOC_007395	COG3132	Protein of unknown function, DUF480
PB20LOC_007405	COG0728	peptidoglycan biosynthetic process
PB20LOC_007410	COG0018	arginyl-trna synthetase
PB20LOC_007415	COG3102	Protein conserved in bacteria
PB20LOC_007420	COG3142	Participates in the control of copper homeostasis
PB20LOC_007450	COG0500	methyltransferase
PB20LOC_007455	COG2226	methyltransferase
PB20LOC_007460	COG3788	relative of glutathione S-transferase, MAPEG superfamily
PB20LOC_007465	COG1801	Protein of unknown function DUF72
PB20LOC_007470	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PB20LOC_007475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PB20LOC_007480	COG0494	nUDIX hydrolase
PB20LOC_007485	COG0217	transcriptional regulatory protein
PB20LOC_007490	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PB20LOC_007495	COG0632	four-way junction helicase activity
PB20LOC_007500	COG2255	four-way junction helicase activity
PB20LOC_007505	COG4580	involved in the transport of maltose and maltodextrins
PB20LOC_007510	COG1447	Phosphotransferase system cellobiose-specific component IIA
PB20LOC_007515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PB20LOC_007525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PB20LOC_007530	COG1121	(ABC) transporter
PB20LOC_007535	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PB20LOC_007540	COG0739	heme binding
PB20LOC_007545	COG1560	Kdo2-lipid A biosynthetic process
PB20LOC_007550	COG0469	pyruvate kinase activity
PB20LOC_007555	COG1737	Transcriptional regulator
PB20LOC_007560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PB20LOC_007565	COG0800	Aldolase
PB20LOC_007570	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PB20LOC_007575	COG1770	oligopeptidase
PB20LOC_007585	COG1528	Iron-storage protein
PB20LOC_007605	COG1278	Cold shock
PB20LOC_007620	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PB20LOC_007635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PB20LOC_007635	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
PB20LOC_007640	COG3008	intermembrane lipid transfer
PB20LOC_007645	COG2995	paraquat-inducible protein a
PB20LOC_007650	COG1956	GAF domain-containing protein
PB20LOC_007655	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
PB20LOC_007665	COG2207	Transcriptional regulator
PB20LOC_007680	COG1177	transmembrane transport
PB20LOC_007690	COG3842	ATPase activity
PB20LOC_007695	COG2195	Cleaves the N-terminal amino acid of tripeptides
PB20LOC_007700	COG2850	peptidyl-arginine hydroxylation
PB20LOC_007715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PB20LOC_007720	COG2915	High frequency lysogenization protein hflD homolog
PB20LOC_007725	COG0482	sulfurtransferase activity
PB20LOC_007735	COG1187	pseudouridine synthase activity
PB20LOC_007740	COG0538	isocitrate dehydrogenase activity
PB20LOC_007760	COG0538	isocitrate dehydrogenase activity
PB20LOC_007775	COG2801	Transposase and inactivated derivatives
PB20LOC_007785	COG0348	domain, Protein
PB20LOC_007810	COG3275	phosphorelay sensor kinase activity
PB20LOC_007815	COG3279	Response regulator of the LytR AlgR family
PB20LOC_007820	COG2223	nitrite transmembrane transporter activity
PB20LOC_007825	COG1653	transport
PB20LOC_007835	COG0501	Belongs to the peptidase M48B family
PB20LOC_007840	COG0823	Involved in the tonB-independent uptake of proteins
PB20LOC_007855	COG1113	amino acid transport
PB20LOC_007860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PB20LOC_007865	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PB20LOC_007870	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PB20LOC_007875	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PB20LOC_007885	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PB20LOC_007890	COG0072	phenylalanine-tRNA ligase activity
PB20LOC_007890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PB20LOC_007895	COG0776	regulation of translation
PB20LOC_007910	COG1132	(ABC) transporter
PB20LOC_007920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PB20LOC_007925	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PB20LOC_007930	COG1823	symporter activity
PB20LOC_007935	COG1988	membrane-bound metal-dependent
PB20LOC_007940	COG2755	lipolytic protein G-D-S-L family
PB20LOC_007940	COG0657	acetylesterase activity
PB20LOC_007945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PB20LOC_007950	COG1653	transport
PB20LOC_007955	COG3842	ATPase activity
PB20LOC_007960	COG0395	ABC-type sugar transport system, permease component
PB20LOC_007965	COG1175	transmembrane transport
PB20LOC_007975	COG1028	Short-chain dehydrogenase reductase Sdr
PB20LOC_007980	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PB20LOC_007985	COG1917	Cupin 2, conserved barrel domain protein
PB20LOC_007990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PB20LOC_008000	COG3001	Fructosamine kinase
PB20LOC_008005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PB20LOC_008010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PB20LOC_008015	COG1121	(ABC) transporter
PB20LOC_008020	COG0803	Belongs to the bacterial solute-binding protein 9 family
PB20LOC_008035	COG2226	methyltransferase
PB20LOC_008040	COG1971	Probably functions as a manganese efflux pump
PB20LOC_008045	COG4811	Protein of unknown function (DUF986)
PB20LOC_008050	COG3716	PTS system mannose fructose sorbose family IID component
PB20LOC_008055	COG3715	PTS system
PB20LOC_008060	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB20LOC_008060	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB20LOC_008065	COG1253	flavin adenine dinucleotide binding
PB20LOC_008070	COG1760	l-serine dehydratase
PB20LOC_008075	COG0494	nUDIX hydrolase
PB20LOC_008085	COG3140	Belongs to the UPF0181 family
PB20LOC_008090	COG0251	oxidation-reduction process
PB20LOC_008095	COG1199	ATP-dependent helicase activity
PB20LOC_008105	COG3065	identical protein binding
PB20LOC_008110	COG0318	PFAM AMP-dependent synthetase and ligase
PB20LOC_008115	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PB20LOC_008120	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PB20LOC_008125	COG2894	cell division
PB20LOC_008130	COG0850	regulation of cytokinetic process
PB20LOC_008135	COG3100	YcgL domain-containing protein
PB20LOC_008140	COG0179	Fumarylacetoacetate (FAA) hydrolase
PB20LOC_008145	COG2983	Belongs to the UPF0260 family
PB20LOC_008165	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PB20LOC_008170	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PB20LOC_008175	COG2186	Transcriptional regulator
PB20LOC_008180	COG2719	SpoVR family
PB20LOC_008185	COG3684	Belongs to the aldolase LacD family
PB20LOC_008195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB20LOC_008215	COG0205	6-phosphofructokinase activity
PB20LOC_008220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PB20LOC_008235	COG2718	Belongs to the UPF0229 family
PB20LOC_008240	COG2766	serine protein kinase
PB20LOC_008245	COG3713	MltA-interacting MipA family protein
PB20LOC_008250	COG0656	L-ascorbic acid biosynthetic process
PB20LOC_008260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PB20LOC_008265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PB20LOC_008270	COG3139	Protein of unknown function (DUF1315)
PB20LOC_008275	COG1335	isochorismatase
PB20LOC_008280	COG0252	asparaginase activity
PB20LOC_008285	COG0616	signal peptide processing
PB20LOC_008290	COG0778	Nitroreductase
PB20LOC_008295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PB20LOC_008305	COG0708	Exodeoxyribonuclease III
PB20LOC_008310	COG2860	membrane
PB20LOC_008330	COG0788	formyltetrahydrofolate deformylase activity
PB20LOC_008335	COG3012	SEC-C Motif Domain Protein
PB20LOC_008340	COG1752	Esterase of the alpha-beta hydrolase superfamily
PB20LOC_008345	COG0745	RESPONSE REGULATOR receiver
PB20LOC_008350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PB20LOC_008360	COG1435	thymidine kinase activity
PB20LOC_008365	COG1012	belongs to the aldehyde dehydrogenase family
PB20LOC_008365	COG1454	alcohol dehydrogenase
PB20LOC_008380	COG0601	transmembrane transport
PB20LOC_008385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB20LOC_008390	COG0444	Belongs to the ABC transporter superfamily
PB20LOC_008400	COG3099	Belongs to the UPF0263 family
PB20LOC_008405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PB20LOC_008420	COG2350	Protein conserved in bacteria
PB20LOC_008430	COG1607	acyl-coa hydrolase
PB20LOC_008435	COG2917	probably involved in intracellular septation
PB20LOC_008445	COG3047	cAMP biosynthetic process
PB20LOC_008450	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PB20LOC_008455	COG0159	tryptophan synthase activity
PB20LOC_008460	COG0133	tryptophan synthase activity
PB20LOC_008465	COG0134	indole-3-glycerol-phosphate synthase activity
PB20LOC_008465	COG0135	phosphoribosylanthranilate isomerase activity
PB20LOC_008470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PB20LOC_008475	COG0512	Glutamine amidotransferase of anthranilate synthase
PB20LOC_008490	COG1215	transferase activity, transferring glycosyl groups
PB20LOC_008495	COG0613	PHP domain protein
PB20LOC_008500	COG0009	L-threonylcarbamoyladenylate synthase
PB20LOC_008505	COG1187	pseudouridine synthase activity
PB20LOC_008510	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
PB20LOC_008515	COG1028	Short-chain dehydrogenase reductase Sdr
PB20LOC_008520	COG0616	signal peptide processing
PB20LOC_008540	COG3104	oligopeptide transport
PB20LOC_008545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PB20LOC_008555	COG4659	FMN binding
PB20LOC_008560	COG4658	electron transport chain
PB20LOC_008565	COG4656	Part of a membrane complex involved in electron transport
PB20LOC_008570	COG2878	Part of a membrane complex involved in electron transport
PB20LOC_008575	COG4657	Part of a membrane complex involved in electron transport
PB20LOC_008585	COG2160	L-arabinose isomerase activity
PB20LOC_008590	COG1069	ribulokinase activity
PB20LOC_008595	COG1879	ABC-type sugar transport system periplasmic component
PB20LOC_008600	COG1129	ABC transporter
PB20LOC_008605	COG1172	Belongs to the binding-protein-dependent transport system permease family
PB20LOC_008615	COG0673	inositol 2-dehydrogenase activity
PB20LOC_008620	COG0385	Bile acid
PB20LOC_008635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PB20LOC_008645	COG5339	Protein conserved in bacteria
PB20LOC_008650	COG1482	cell wall glycoprotein biosynthetic process
PB20LOC_008655	COG0114	fumarate hydratase activity
PB20LOC_008665	COG2814	Major facilitator Superfamily
PB20LOC_008670	COG0583	DNA-binding transcription factor activity
PB20LOC_008675	COG1940	carbohydrate kinase activity
PB20LOC_008685	COG0477	Major facilitator Superfamily
PB20LOC_008705	COG4221	oxidoreductase activity
PB20LOC_008710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PB20LOC_008715	COG1942	4-Oxalocrotonate Tautomerase
PB20LOC_008720	COG0076	glutamate decarboxylase activity
PB20LOC_008725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PB20LOC_008730	COG1649	PFAM Uncharacterised BCR, COG1649
PB20LOC_008735	COG4628	conserved protein (DUF2132)
PB20LOC_008745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PB20LOC_008750	COG2267	carboxylic ester hydrolase activity
PB20LOC_008755	COG2453	phosphatase
PB20LOC_008755	COG0671	phosphoesterase, PA-phosphatase related
PB20LOC_008785	COG0456	acetyltransferase
PB20LOC_008790	COG0738	Major facilitator superfamily
PB20LOC_008805	COG2801	Transposase and inactivated derivatives
PB20LOC_008810	COG0583	DNA-binding transcription factor activity
PB20LOC_008815	COG0604	alcohol dehydrogenase
PB20LOC_008820	COG4305	rare lipoprotein A
PB20LOC_008845	COG1349	DNA-binding transcription factor activity
PB20LOC_008855	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB20LOC_008865	COG3716	PTS system mannose fructose sorbose family IID component
PB20LOC_008870	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB20LOC_008875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PB20LOC_008880	COG2222	sugar isomerase
PB20LOC_008885	COG0191	fructose-bisphosphate aldolase activity
PB20LOC_008900	COG0673	inositol 2-dehydrogenase activity
PB20LOC_008905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PB20LOC_008910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PB20LOC_008920	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PB20LOC_008925	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PB20LOC_008935	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PB20LOC_008940	COG2912	Transglutaminase-like superfamily
PB20LOC_008950	COG2890	protein-(glutamine-N5) methyltransferase activity
PB20LOC_008955	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PB20LOC_008960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PB20LOC_008965	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PB20LOC_008970	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PB20LOC_008975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PB20LOC_008985	COG0193	aminoacyl-tRNA hydrolase activity
PB20LOC_008990	COG0012	GTP binding
PB20LOC_009115	COG0515	serine threonine protein kinase
PB20LOC_009225	COG1121	(ABC) transporter
PB20LOC_009230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PB20LOC_009270	COG0346	lactoylglutathione lyase activity
PB20LOC_009275	COG0483	inositol monophosphate 1-phosphatase activity
PB20LOC_009280	COG2723	6-phospho-beta-galactosidase activity
PB20LOC_009285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB20LOC_009285	COG1263	PTS System
PB20LOC_009290	COG1609	Transcriptional regulator
PB20LOC_009300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PB20LOC_009305	COG1473	amidohydrolase
PB20LOC_009315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PB20LOC_009320	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PB20LOC_009325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB20LOC_009335	COG0765	amino acid transport
PB20LOC_009340	COG1126	abc transporter atp-binding protein
PB20LOC_009345	COG2314	TM2 domain
PB20LOC_009355	COG1129	ABC transporter
PB20LOC_009370	COG0683	leucine binding
PB20LOC_009390	COG3507	Belongs to the glycosyl hydrolase 43 family
PB20LOC_009395	COG2211	Major facilitator Superfamily
PB20LOC_009480	COG3210	domain, Protein
PB20LOC_009515	COG1802	Transcriptional regulator
PB20LOC_009525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PB20LOC_009530	COG0583	DNA-binding transcription factor activity
PB20LOC_009545	COG1464	Belongs to the NlpA lipoprotein family
PB20LOC_009550	COG4948	Mandelate Racemase Muconate Lactonizing
PB20LOC_009555	COG2011	ABC-type metal ion transport system permease component
PB20LOC_009560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PB20LOC_009570	COG0671	phosphoesterase, PA-phosphatase related
PB20LOC_009580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PB20LOC_009590	COG1028	Short-chain dehydrogenase reductase Sdr
PB20LOC_009600	COG1176	ABC-type spermidine putrescine transport system, permease component I
PB20LOC_009610	COG1012	belongs to the aldehyde dehydrogenase family
PB20LOC_009615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PB20LOC_009625	COG3842	ATPase activity
PB20LOC_009660	COG2261	transglycosylase associated protein
PB20LOC_009675	COG2423	ornithine cyclodeaminase activity
PB20LOC_009685	COG1846	Transcriptional regulator
PB20LOC_009690	COG0697	spore germination
PB20LOC_009695	COG2181	nitrate reductase activity
PB20LOC_009700	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PB20LOC_009705	COG1140	nitrate reductase beta subunit
PB20LOC_009710	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PB20LOC_009715	COG2223	nitrite transmembrane transporter activity
PB20LOC_009720	COG3850	Histidine kinase
PB20LOC_009725	COG2197	response regulator
PB20LOC_009740	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
PB20LOC_009750	COG0387	Pfam Sodium calcium exchanger
PB20LOC_009755	COG0659	secondary active sulfate transmembrane transporter activity
PB20LOC_009775	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PB20LOC_009785	COG0745	RESPONSE REGULATOR receiver
PB20LOC_009790	COG2205	protein histidine kinase activity
PB20LOC_009800	COG3591	Belongs to the peptidase S1B family
PB20LOC_009805	COG5001	Diguanylate cyclase
PB20LOC_009805	COG3300	MHYT domain
PB20LOC_009810	COG1643	Atp-dependent helicase
PB20LOC_009815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PB20LOC_009825	COG2911	Protein conserved in bacteria
PB20LOC_009830	COG0840	transmembrane signaling receptor activity
PB20LOC_009835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PB20LOC_009855	COG0037	tRNA processing
PB20LOC_009865	COG0598	Magnesium transport protein CorA
PB20LOC_009870	COG4166	transmembrane transport
PB20LOC_009875	COG2866	Carboxypeptidase
PB20LOC_009880	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PB20LOC_009895	COG3768	UPF0283 membrane protein
PB20LOC_009900	COG3106	COG3106 Predicted ATPase
PB20LOC_009905	COG1983	PspC domain protein
PB20LOC_009915	COG1842	Phage shock protein A
PB20LOC_009920	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PB20LOC_009925	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PB20LOC_009930	COG4166	transmembrane transport
PB20LOC_009940	COG4171	peptide transport system, permease
PB20LOC_009990	COG1053	succinate dehydrogenase
PB20LOC_010000	COG2271	Major facilitator Superfamily
PB20LOC_010005	COG1609	Transcriptional regulator
PB20LOC_010010	COG0583	DNA-binding transcription factor activity
PB20LOC_010015	COG0243	molybdopterin cofactor binding
PB20LOC_010020	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
PB20LOC_010025	COG4989	oxidoreductase activity
PB20LOC_010030	COG1966	Carbon starvation protein
PB20LOC_010050	COG0235	Class ii aldolase
PB20LOC_010060	COG0023	Translation Initiation Factor
PB20LOC_010065	COG0284	orotidine-5'-phosphate decarboxylase activity
PB20LOC_010070	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PB20LOC_010075	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
PB20LOC_010085	COG1082	Xylose isomerase domain protein TIM barrel
PB20LOC_010090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PB20LOC_010095	COG3958	Transketolase
PB20LOC_010100	COG3959	Transketolase, thiamine diphosphate binding domain
PB20LOC_010105	COG1172	Belongs to the binding-protein-dependent transport system permease family
PB20LOC_010110	COG1129	ABC transporter
PB20LOC_010120	COG1879	ABC-type sugar transport system periplasmic component
PB20LOC_010125	COG0671	phosphoesterase, PA-phosphatase related
PB20LOC_010130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PB20LOC_010145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PB20LOC_010150	COG1301	dicarboxylic acid transport
PB20LOC_010155	COG0625	glutathione transferase activity
PB20LOC_010160	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PB20LOC_010165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PB20LOC_010170	COG0259	pyridoxamine-phosphate oxidase activity
PB20LOC_010175	COG3895	Periplasmic Protein
PB20LOC_010180	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PB20LOC_010190	COG1846	Transcriptional regulator
PB20LOC_010195	COG3313	Fe-S protein
PB20LOC_010200	COG0346	lactoylglutathione lyase activity
PB20LOC_010205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PB20LOC_010210	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PB20LOC_010215	COG0791	NLP P60 protein
PB20LOC_010225	COG1609	Transcriptional regulator
PB20LOC_010230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PB20LOC_010235	COG0307	riboflavin synthase, alpha
PB20LOC_010240	COG0534	Mate efflux family protein
PB20LOC_010250	COG1620	l-lactate permease
PB20LOC_010255	COG0247	lactate metabolic process
PB20LOC_010260	COG1139	Iron-sulfur cluster binding protein
PB20LOC_010265	COG1556	Lactate utilization protein
PB20LOC_010285	COG3665	Urea carboxylase-associated protein
PB20LOC_010290	COG3842	ATPase activity
PB20LOC_010315	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PB20LOC_010335	COG3829	transcription factor binding
PB20LOC_010350	COG4104	PAAR repeat-containing protein
PB20LOC_010350	COG3209	COG3209 Rhs family protein
PB20LOC_010360	COG3501	Rhs element vgr protein
PB20LOC_010385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PB20LOC_010400	COG1704	LemA family
PB20LOC_010440	COG2197	response regulator
PB20LOC_010445	COG3850	Histidine kinase
PB20LOC_010450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PB20LOC_010450	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
PB20LOC_010455	COG3062	negative regulation of establishment of protein localization
PB20LOC_010460	COG0243	molybdopterin cofactor binding
PB20LOC_010465	COG0437	4 iron, 4 sulfur cluster binding
PB20LOC_010470	COG0348	domain, Protein
PB20LOC_010475	COG3043	anaerobic respiration
PB20LOC_010480	COG3005	denitrification pathway
PB20LOC_010485	COG3088	subunit of a heme lyase
PB20LOC_010485	COG4235	cytochrome complex assembly
PB20LOC_010490	COG3088	subunit of a heme lyase
PB20LOC_010490	COG4235	cytochrome complex assembly
PB20LOC_010495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PB20LOC_010500	COG1138	Cytochrome C-type biogenesis protein
PB20LOC_010505	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PB20LOC_010510	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PB20LOC_010515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PB20LOC_010520	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PB20LOC_010525	COG4133	protoheme IX ABC transporter activity
PB20LOC_010530	COG4235	cytochrome complex assembly
PB20LOC_010535	COG3088	subunit of a heme lyase
PB20LOC_010540	COG1138	Cytochrome C-type biogenesis protein
PB20LOC_010545	COG3301	Polysulphide reductase, NrfD
PB20LOC_010550	COG0437	4 iron, 4 sulfur cluster binding
PB20LOC_010555	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
PB20LOC_010560	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
PB20LOC_010575	COG2382	esterase
PB20LOC_010610	COG4238	major outer membrane lipoprotein
PB20LOC_010615	COG1376	ErfK ybiS ycfS ynhG family protein
PB20LOC_010615	COG1388	LysM domain
PB20LOC_010620	COG2166	iron-sulfur cluster assembly
PB20LOC_010625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PB20LOC_010630	COG0719	Fe-S assembly protein
PB20LOC_010635	COG0396	ATPase activity
PB20LOC_010640	COG0719	Fe-S assembly protein
PB20LOC_010645	COG0316	Belongs to the HesB IscA family
PB20LOC_010655	COG2050	protein possibly involved in aromatic compounds catabolism
PB20LOC_010660	COG0277	FAD linked oxidase domain protein
PB20LOC_010660	COG0247	lactate metabolic process
PB20LOC_010665	COG0628	permease
PB20LOC_010675	COG1477	protein flavinylation
PB20LOC_010680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PB20LOC_010680	COG0574	Belongs to the PEP-utilizing enzyme family
PB20LOC_010685	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PB20LOC_010690	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PB20LOC_010695	COG3720	iron ion transport
PB20LOC_010700	COG4558	Periplasmic binding protein
PB20LOC_010705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB20LOC_010710	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PB20LOC_010715	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PB20LOC_010730	COG2610	gluconate transmembrane transporter activity
PB20LOC_010735	COG3265	gluconokinase activity
PB20LOC_010740	COG1609	Transcriptional regulator
PB20LOC_010745	COG0129	dihydroxy-acid dehydratase activity
PB20LOC_010750	COG0791	NLP P60 protein
PB20LOC_010755	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
PB20LOC_010760	COG0386	Belongs to the glutathione peroxidase family
PB20LOC_010765	COG4139	cobalamin transport
PB20LOC_010770	COG2226	methyltransferase
PB20LOC_010790	COG1940	carbohydrate kinase activity
PB20LOC_010795	COG4591	ABC-type transport system involved in lipoprotein release permease component
PB20LOC_010800	COG1136	(ABC) transporter
PB20LOC_010805	COG4591	ABC-type transport system involved in lipoprotein release permease component
PB20LOC_010810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PB20LOC_010815	COG0443	Heat shock 70 kDa protein
PB20LOC_010820	COG1309	transcriptional regulator
PB20LOC_010830	COG2814	Major facilitator Superfamily
PB20LOC_010835	COG3134	Outer membrane lipoprotein
PB20LOC_010840	COG1252	NADH dehydrogenase
PB20LOC_010845	COG3150	esterase
PB20LOC_010850	COG1472	Belongs to the glycosyl hydrolase 3 family
PB20LOC_010860	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
PB20LOC_010870	COG0537	adenosine 5'-monophosphoramidase activity
PB20LOC_010875	COG1263	PTS System
PB20LOC_010875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB20LOC_010880	COG0084	hydrolase, TatD family'
PB20LOC_010885	COG0470	DNA polymerase III
PB20LOC_010890	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PB20LOC_010895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PB20LOC_010900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PB20LOC_010905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PB20LOC_010910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PB20LOC_010915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PB20LOC_010925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PB20LOC_010930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PB20LOC_010935	COG0416	fatty acid biosynthetic process
PB20LOC_010940	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PB20LOC_010945	COG1399	metal-binding, possibly nucleic acid-binding protein
PB20LOC_010950	COG0424	maF-like protein
PB20LOC_010955	COG0564	pseudouridine synthase activity
PB20LOC_010960	COG1530	ribonuclease E activity
PB20LOC_010960	COG1530	ribonuclease E activity
PB20LOC_010970	COG0418	dihydroorotase activity
PB20LOC_010990	COG3038	cytochrome b561
PB20LOC_010995	COG2353	YceI-like domain
PB20LOC_011000	COG1054	Belongs to the UPF0176 family
PB20LOC_011005	COG1902	pentaerythritol trinitrate reductase activity
PB20LOC_011010	COG1560	Kdo2-lipid A biosynthetic process
PB20LOC_011015	COG2943	transferase activity, transferring hexosyl groups
PB20LOC_011020	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PB20LOC_011035	COG0840	transmembrane signaling receptor activity
PB20LOC_011055	COG1683	Conserved Protein
PB20LOC_011060	COG0589	response to stress
PB20LOC_011115	COG0670	Belongs to the BI1 family
PB20LOC_011120	COG2920	part of a sulfur-relay system
PB20LOC_011125	COG1254	Belongs to the acylphosphatase family
PB20LOC_011130	COG3785	DNA binding
PB20LOC_011135	COG1832	CoA-binding protein
PB20LOC_011145	COG1803	Methylglyoxal synthase
PB20LOC_011150	COG0210	DNA helicase
PB20LOC_011155	COG3304	Inner membrane component domain
PB20LOC_011160	COG1289	transmembrane transporter activity
PB20LOC_011165	COG3070	regulator of competence-specific genes
PB20LOC_011170	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
PB20LOC_011185	COG1067	ATP-dependent peptidase activity
PB20LOC_011190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PB20LOC_011195	COG2979	Protein of unknown function (DUF533)
PB20LOC_011220	COG3122	Protein conserved in bacteria
PB20LOC_011240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PB20LOC_011245	COG0534	Mate efflux family protein
PB20LOC_011250	COG2807	transmembrane transport
PB20LOC_011255	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PB20LOC_011265	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PB20LOC_011265	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PB20LOC_011270	COG0783	Belongs to the Dps family
PB20LOC_011275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB20LOC_011280	COG0765	amino acid transport
PB20LOC_011285	COG1126	abc transporter atp-binding protein
PB20LOC_011295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PB20LOC_011445	COG1280	lysine exporter protein (LysE YggA)
PB20LOC_011450	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
PB20LOC_011470	COG3842	ATPase activity
PB20LOC_011475	COG1177	transmembrane transport
PB20LOC_011480	COG1349	DNA-binding transcription factor activity
PB20LOC_011490	COG1686	Belongs to the peptidase S11 family
PB20LOC_011510	COG2040	homocysteine
PB20LOC_011515	COG0833	amino acid
PB20LOC_011520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PB20LOC_011525	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PB20LOC_011530	COG0747	negative chemotaxis
PB20LOC_011535	COG2195	Cleaves the N-terminal amino acid of tripeptides
PB20LOC_011555	COG0513	Belongs to the DEAD box helicase family
PB20LOC_011565	COG1120	ATPase activity
PB20LOC_011570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB20LOC_011575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB20LOC_011580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PB20LOC_011595	COG1131	(ABC) transporter
PB20LOC_011600	COG0842	Transport permease protein
PB20LOC_011605	COG0842	Transport permease protein
PB20LOC_011610	COG0670	Belongs to the BI1 family
PB20LOC_011615	COG0314	molybdopterin synthase activity
PB20LOC_011620	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PB20LOC_011625	COG0315	cyclic pyranopterin monophosphate synthase activity
PB20LOC_011630	COG0521	Mo-molybdopterin cofactor biosynthetic process
PB20LOC_011635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PB20LOC_011655	COG0556	nucleotide-excision repair
PB20LOC_011670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PB20LOC_011675	COG2226	methyltransferase
PB20LOC_011680	COG0156	8-amino-7-oxononanoate synthase activity
PB20LOC_011685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PB20LOC_011695	COG5297	Belongs to the glycosyl hydrolase family 6
PB20LOC_011700	COG1380	Effector of murein hydrolase LrgA
PB20LOC_011705	COG1346	cytolysis
PB20LOC_011715	COG0295	cytidine deaminase activity
PB20LOC_011720	COG0281	malic enzyme
PB20LOC_011725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB20LOC_011730	COG0601	transmembrane transport
PB20LOC_011735	COG0747	negative chemotaxis
PB20LOC_011740	COG4172	Belongs to the ABC transporter superfamily
PB20LOC_011745	COG0303	'Molybdopterin
PB20LOC_011750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PB20LOC_011765	COG0401	homolog of Blt101
PB20LOC_011800	COG3615	Tellurite resistance protein tehB
PB20LOC_011810	COG1840	ABC-type Fe3 transport system, periplasmic component
PB20LOC_011815	COG4208	sulfate ABC transporter
PB20LOC_011820	COG3842	ATPase activity
PB20LOC_011835	COG3718	enzyme involved in inositol metabolism
PB20LOC_011845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PB20LOC_011855	COG1172	Belongs to the binding-protein-dependent transport system permease family
PB20LOC_011870	COG0673	inositol 2-dehydrogenase activity
PB20LOC_011875	COG3962	Belongs to the TPP enzyme family
PB20LOC_011900	COG3706	GGDEF domain
PB20LOC_011915	COG1605	Chorismate mutase
PB20LOC_011920	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PB20LOC_011945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PB20LOC_011985	COG1215	transferase activity, transferring glycosyl groups
PB20LOC_011990	COG1215	transferase activity, transferring glycosyl groups
PB20LOC_012030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PB20LOC_012035	COG1253	flavin adenine dinucleotide binding
PB20LOC_012040	COG3069	C4-dicarboxylate transmembrane transporter activity
PB20LOC_012045	COG2982	Protein involved in outer membrane biogenesis
PB20LOC_012050	COG0717	Belongs to the dCTP deaminase family
PB20LOC_012055	COG0572	uridine kinase
PB20LOC_012060	COG0489	protein tyrosine kinase activity
PB20LOC_012065	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PB20LOC_012065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PB20LOC_012070	COG0243	molybdopterin cofactor binding
PB20LOC_012070	COG3383	formate dehydrogenase (NAD+) activity
PB20LOC_012075	COG0437	4 iron, 4 sulfur cluster binding
PB20LOC_012080	COG2864	formate dehydrogenase
PB20LOC_012100	COG2706	6-phosphogluconolactonase activity
PB20LOC_012105	COG2916	Histone family protein nucleoid-structuring protein H-NS
PB20LOC_012120	COG0561	phosphatase activity
PB20LOC_012125	COG0837	glucose binding
PB20LOC_012130	COG2211	Major facilitator Superfamily
PB20LOC_012155	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PB20LOC_012160	COG4149	molybdate abc transporter
PB20LOC_012165	COG0725	ABC transporter, periplasmic molybdate-binding protein
PB20LOC_012175	COG3585	molybdate ion transport
PB20LOC_012175	COG2005	Transcriptional regulator
PB20LOC_012180	COG1119	ATPase activity
PB20LOC_012185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PB20LOC_012190	COG2017	converts alpha-aldose to the beta-anomer
PB20LOC_012210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PB20LOC_012215	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PB20LOC_012220	COG0588	phosphoglycerate mutase activity
PB20LOC_012225	COG0583	DNA-binding transcription factor activity
PB20LOC_012230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PB20LOC_012240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PB20LOC_012245	COG1230	cation diffusion facilitator family transporter
PB20LOC_012255	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PB20LOC_012265	COG1811	Na channel or pump
PB20LOC_012290	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PB20LOC_012295	COG2885	chlorophyll binding
PB20LOC_012300	COG0823	Involved in the tonB-independent uptake of proteins
PB20LOC_012305	COG3064	Membrane
PB20LOC_012310	COG0848	biopolymer transport protein
PB20LOC_012315	COG0811	peptide transport
PB20LOC_012320	COG0824	Thioesterase
PB20LOC_012325	COG3790	cyd operon protein YbgE
PB20LOC_012330	COG4890	Cyd operon protein YbgT
PB20LOC_012335	COG1294	oxidase, subunit
PB20LOC_012340	COG1271	oxidase subunit
PB20LOC_012350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PB20LOC_012355	COG0045	succinate-CoA ligase (ADP-forming) activity
PB20LOC_012360	COG0508	dehydrogenase complex catalyzes the overall conversion of
PB20LOC_012365	COG0567	Dehydrogenase, E1 component
PB20LOC_012370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PB20LOC_012375	COG1053	succinate dehydrogenase
PB20LOC_012380	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PB20LOC_012395	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PB20LOC_012400	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PB20LOC_012405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PB20LOC_012410	COG1984	allophanate hydrolase subunit 2
PB20LOC_012415	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PB20LOC_012420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PB20LOC_012425	COG0415	Belongs to the DNA photolyase family
PB20LOC_012430	COG3272	Protein of unknown function (DUF1722)
PB20LOC_012450	COG2205	protein histidine kinase activity
PB20LOC_012465	COG0033	Phosphoglucomutase
PB20LOC_012470	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
PB20LOC_012475	COG0596	Alpha beta hydrolase
PB20LOC_012485	COG0840	transmembrane signaling receptor activity
PB20LOC_012495	COG0735	belongs to the Fur family
PB20LOC_012500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PB20LOC_012505	COG1263	PTS System
PB20LOC_012505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB20LOC_012505	COG2190	(PTS) system
PB20LOC_012510	COG0363	glucosamine-6-phosphate deaminase activity
PB20LOC_012515	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PB20LOC_012520	COG1846	Transcriptional regulator
PB20LOC_012520	COG1940	carbohydrate kinase activity
PB20LOC_012525	COG0367	asparagine synthase
PB20LOC_012565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PB20LOC_012570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PB20LOC_012575	COG1702	phosphate starvation-inducible protein PhoH
PB20LOC_012580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PB20LOC_012585	COG4535	Mg2 and Co2 transporter CorC
PB20LOC_012590	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PB20LOC_012600	COG0765	amino acid transport
PB20LOC_012605	COG0765	amino acid transport
PB20LOC_012610	COG1126	abc transporter atp-binding protein
PB20LOC_012615	COG2888	peptidyl-tyrosine sulfation
PB20LOC_012620	COG0495	leucyl-tRNA aminoacylation
PB20LOC_012625	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
PB20LOC_012630	COG1466	dna polymerase III delta subunit
PB20LOC_012635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PB20LOC_012640	COG0799	negative regulation of ribosome biogenesis
PB20LOC_012645	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PB20LOC_012650	COG0768	penicillin binding
PB20LOC_012655	COG0772	Belongs to the SEDS family
PB20LOC_012660	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PB20LOC_012665	COG1686	Belongs to the peptidase S11 family
PB20LOC_012670	COG2921	Belongs to the UPF0250 family
PB20LOC_012675	COG0321	lipoyl(octanoyl) transferase activity
PB20LOC_012680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PB20LOC_012685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PB20LOC_012690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PB20LOC_012700	COG1794	racemase activity, acting on amino acids and derivatives
PB20LOC_012710	COG1393	Belongs to the ArsC family
PB20LOC_012715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PB20LOC_012720	COG1876	peptidase activity
PB20LOC_012730	COG0583	DNA-binding transcription factor activity
PB20LOC_012735	COG2851	Citrate transporter
PB20LOC_012750	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PB20LOC_012755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PB20LOC_012760	COG0183	Belongs to the thiolase family
PB20LOC_012770	COG0400	carboxylic ester hydrolase activity
PB20LOC_012775	COG3813	Protein conserved in bacteria
PB20LOC_012780	COG1444	tRNA N-acetyltransferase activity
PB20LOC_012785	COG2707	UPF0756 membrane protein
PB20LOC_012790	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PB20LOC_012795	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PB20LOC_012805	COG2716	regulation of RNA biosynthetic process
PB20LOC_012810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PB20LOC_012815	COG4783	chaperone-mediated protein folding
PB20LOC_012820	COG1393	Belongs to the ArsC family
PB20LOC_012825	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PB20LOC_012830	COG2233	PERMEase
PB20LOC_012835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PB20LOC_012840	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PB20LOC_012845	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PB20LOC_012855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB20LOC_012860	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PB20LOC_012865	COG4181	ATPase activity
PB20LOC_012870	COG2755	lipolytic protein G-D-S-L family
PB20LOC_012875	COG0300	oxidoreductase activity
PB20LOC_012880	COG3118	belongs to the thioredoxin family
PB20LOC_012890	COG0814	amino acid
PB20LOC_012905	COG1441	menaquinone biosynthetic process
PB20LOC_012910	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PB20LOC_012915	COG0596	Alpha beta hydrolase
PB20LOC_012920	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PB20LOC_012925	COG1169	isochorismate synthase
PB20LOC_012930	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
PB20LOC_012935	COG1733	regulation of RNA biosynthetic process
PB20LOC_012940	COG2223	nitrite transmembrane transporter activity
PB20LOC_012945	COG2198	Histidine kinase
PB20LOC_012945	COG0642	Histidine kinase
PB20LOC_012950	COG2197	response regulator
PB20LOC_012955	COG0784	Response regulator, receiver
PB20LOC_012955	COG2205	protein histidine kinase activity
PB20LOC_012965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PB20LOC_012970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PB20LOC_012980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PB20LOC_012985	COG0330	HflC and HflK could
PB20LOC_012990	COG1585	Membrane protein implicated in regulation of membrane protease activity
PB20LOC_013005	COG2217	Heavy metal translocating P-type atpase
PB20LOC_013010	COG3735	TraB family
PB20LOC_013020	COG5434	Belongs to the glycosyl hydrolase 28 family
PB20LOC_013025	COG0523	cobalamin synthesis protein
PB20LOC_013030	COG2879	small protein
PB20LOC_013035	COG1966	Carbon starvation protein
PB20LOC_013045	COG0737	Belongs to the 5'-nucleotidase family
PB20LOC_013050	COG4651	solute:proton antiporter activity
PB20LOC_013050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PB20LOC_013055	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PB20LOC_013060	COG0563	adenylate kinase activity
PB20LOC_013065	COG0326	Molecular chaperone. Has ATPase activity
PB20LOC_013070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PB20LOC_013075	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PB20LOC_013085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PB20LOC_013090	COG2832	Protein of unknown function (DUF454)
PB20LOC_013105	COG1309	transcriptional regulator
PB20LOC_013110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PB20LOC_013115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PB20LOC_013120	COG0254	rRNA binding
PB20LOC_013125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PB20LOC_013145	COG3695	enzyme binding
PB20LOC_013150	COG3126	Type III secretion system lipoprotein chaperone (YscW)
PB20LOC_013155	COG1946	Acyl-CoA thioesterase
PB20LOC_013160	COG0004	ammonium transporteR
PB20LOC_013165	COG0347	Belongs to the P(II) protein family
PB20LOC_013170	COG1132	(ABC) transporter
PB20LOC_013175	COG1132	(ABC) transporter
PB20LOC_013180	COG1522	sequence-specific DNA binding
PB20LOC_013190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PB20LOC_013195	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PB20LOC_013200	COG0824	Thioesterase
PB20LOC_013205	COG1555	photosystem II stabilization
PB20LOC_013210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PB20LOC_013215	COG0776	regulation of translation
PB20LOC_013220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PB20LOC_013225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PB20LOC_013230	COG0740	serine-type endopeptidase activity
PB20LOC_013235	COG0544	peptidyl-prolyl cis-trans isomerase activity
PB20LOC_013240	COG0271	Belongs to the BolA IbaG family
PB20LOC_013245	COG3056	Lipoprotein
PB20LOC_013250	COG2223	nitrite transmembrane transporter activity
PB20LOC_013255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PB20LOC_013260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PB20LOC_013265	COG1845	cytochrome c oxidase, subunit III
PB20LOC_013270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PB20LOC_013275	COG0109	protoheme IX farnesyltransferase activity
PB20LOC_013280	COG2814	Major facilitator Superfamily
PB20LOC_013285	COG1666	GTP binding
PB20LOC_013290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PB20LOC_013295	COG0693	protein deglycase activity
PB20LOC_013300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PB20LOC_013300	COG0301	tRNA thio-modification
PB20LOC_013305	COG1722	exodeoxyribonuclease VII activity
PB20LOC_013310	COG0142	geranyltranstransferase activity
PB20LOC_013315	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PB20LOC_013320	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PB20LOC_013325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PB20LOC_013330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PB20LOC_013335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PB20LOC_013335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PB20LOC_013340	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PB20LOC_013350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PB20LOC_013360	COG1862	Preprotein translocase
PB20LOC_013365	COG0343	queuine tRNA-ribosyltransferase activity
PB20LOC_013370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PB20LOC_013375	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
PB20LOC_013380	COG0450	alkyl hydroperoxide reductase
PB20LOC_013385	COG0668	transmembrane transport
PB20LOC_013400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PB20LOC_013420	COG0420	3'-5' exonuclease activity
PB20LOC_013425	COG0419	ATPase involved in DNA repair
PB20LOC_013430	COG1940	carbohydrate kinase activity
PB20LOC_013435	COG2974	May be involved in recombination
PB20LOC_013445	COG2188	Transcriptional regulator
PB20LOC_013450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PB20LOC_013455	COG1397	ADP-ribosylglycohydrolase
PB20LOC_013460	COG2211	Major facilitator Superfamily
PB20LOC_013465	COG3123	guanosine phosphorylase activity
PB20LOC_013470	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PB20LOC_013480	COG4615	Cyclic peptide transporter
PB20LOC_013495	COG1132	(ABC) transporter
PB20LOC_013505	COG5434	Belongs to the glycosyl hydrolase 28 family
PB20LOC_013510	COG5297	Belongs to the glycosyl hydrolase family 6
PB20LOC_013515	COG1312	Catalyzes the dehydration of D-mannonate
PB20LOC_013520	COG2186	Transcriptional regulator
PB20LOC_013550	COG0583	DNA-binding transcription factor activity
PB20LOC_013560	COG2951	lytic endotransglycosylase activity
PB20LOC_013565	COG2824	Alkylphosphonate utilization operon protein PhnA
PB20LOC_013570	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PB20LOC_013580	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PB20LOC_013585	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PB20LOC_013590	COG3015	lipoprotein NlpE involved in copper resistance
PB20LOC_013605	COG4568	rho-dependent transcription termination
PB20LOC_013610	COG0037	tRNA processing
PB20LOC_013615	COG0346	lactoylglutathione lyase activity
PB20LOC_013620	COG0825	malonyl-CoA metabolic process
PB20LOC_013625	COG0587	DNA-directed DNA polymerase activity
PB20LOC_013630	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PB20LOC_013635	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PB20LOC_013640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PB20LOC_013645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PB20LOC_013650	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PB20LOC_013655	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
PB20LOC_013660	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PB20LOC_013665	COG0750	zinc metalloprotease
PB20LOC_013670	COG0575	Belongs to the CDS family
PB20LOC_013675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PB20LOC_013680	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PB20LOC_013685	COG0233	cytoplasmic translational termination
PB20LOC_013690	COG0528	UMP kinase activity
PB20LOC_013695	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PB20LOC_013700	COG0052	Belongs to the universal ribosomal protein uS2 family
PB20LOC_013710	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PB20LOC_013715	COG2171	N-acyltransferase activity
PB20LOC_013755	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PB20LOC_013755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PB20LOC_013760	COG1611	Belongs to the LOG family
PB20LOC_013765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PB20LOC_013770	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PB20LOC_013775	COG2363	Small membrane protein
PB20LOC_013780	COG0583	DNA-binding transcription factor activity
PB20LOC_013790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PB20LOC_013795	COG2166	iron-sulfur cluster assembly
PB20LOC_013800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PB20LOC_013810	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PB20LOC_013825	COG0860	N-Acetylmuramoyl-L-alanine amidase
PB20LOC_013830	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PB20LOC_013830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PB20LOC_013840	COG1609	Transcriptional regulator
PB20LOC_013845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PB20LOC_013850	COG1074	ATP-dependent DNA helicase activity
PB20LOC_013855	COG1025	Belongs to the peptidase M16 family
PB20LOC_013860	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PB20LOC_013875	COG4795	General secretion pathway protein
PB20LOC_013880	COG4969	Belongs to the N-Me-Phe pilin family
PB20LOC_013885	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PB20LOC_013890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PB20LOC_013900	COG0494	nUDIX hydrolase
PB20LOC_013905	COG3066	DNA modification
PB20LOC_013915	COG0667	Aldo Keto reductase
PB20LOC_013925	COG3171	Protein conserved in bacteria
PB20LOC_013930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PB20LOC_013935	COG1194	a g-specific adenine glycosylase
PB20LOC_013940	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PB20LOC_013945	COG0741	lytic transglycosylase activity
PB20LOC_013950	COG2169	Transcriptional regulator
PB20LOC_013950	COG1917	Cupin 2, conserved barrel domain protein
PB20LOC_013965	COG5564	TIM-barrel signal transduction protein
PB20LOC_013970	COG5441	Belongs to the UPF0261 family
PB20LOC_013985	COG1113	amino acid transport
PB20LOC_013990	COG1982	Orn Lys Arg decarboxylase major
PB20LOC_014000	COG0582	viral genome integration into host DNA
PB20LOC_014045	COG2205	protein histidine kinase activity
PB20LOC_014070	COG0582	viral genome integration into host DNA
PB20LOC_014105	COG2003	Belongs to the UPF0758 family
PB20LOC_014125	COG2378	regulation of single-species biofilm formation
PB20LOC_014130	COG3596	GTP binding
PB20LOC_014135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PB20LOC_014160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PB20LOC_014175	COG4983	Phage plasmid primase, P4 family domain protein
PB20LOC_014200	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PB20LOC_014205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PB20LOC_014225	COG1073	alpha beta
PB20LOC_014230	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
PB20LOC_014235	COG2195	Cleaves the N-terminal amino acid of tripeptides
PB20LOC_014240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PB20LOC_014250	COG2226	methyltransferase
PB20LOC_014255	COG3034	peptidoglycan biosynthetic process
PB20LOC_014260	COG0121	glutamine amidotransferase
PB20LOC_014265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PB20LOC_014270	COG1960	acyl-CoA dehydrogenase activity
PB20LOC_014280	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PB20LOC_014285	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PB20LOC_014320	COG3501	Rhs element vgr protein
PB20LOC_014325	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PB20LOC_014330	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
PB20LOC_014335	COG0235	Class ii aldolase
PB20LOC_014340	COG0436	Aminotransferase
PB20LOC_014350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PB20LOC_014355	COG1882	Formate acetyltransferase
PB20LOC_014360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PB20LOC_014365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PB20LOC_014375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PB20LOC_014385	COG0765	amino acid transport
PB20LOC_014430	COG4175	Glycine betaine
PB20LOC_014435	COG4176	ABC-type proline glycine betaine transport system permease component
PB20LOC_014440	COG2113	Glycine betaine
PB20LOC_014445	COG0596	Alpha beta hydrolase
PB20LOC_014455	COG2706	6-phosphogluconolactonase activity
PB20LOC_014460	COG2814	Major facilitator Superfamily
PB20LOC_014465	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PB20LOC_014475	COG1846	Transcriptional regulator
PB20LOC_014480	COG1566	PFAM secretion protein HlyD family protein
PB20LOC_014485	COG2814	Major facilitator Superfamily
PB20LOC_014500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PB20LOC_014505	COG3118	belongs to the thioredoxin family
PB20LOC_014510	COG3148	PFAM DTW domain containing protein
PB20LOC_014515	COG1042	CoA-binding domain protein
PB20LOC_014515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PB20LOC_014515	COG0045	succinate-CoA ligase (ADP-forming) activity
PB20LOC_014520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PB20LOC_014525	COG5544	Lipoprotein
PB20LOC_014530	COG0477	Major facilitator Superfamily
PB20LOC_014565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PB20LOC_014570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PB20LOC_014575	COG2011	ABC-type metal ion transport system permease component
PB20LOC_014580	COG1464	Belongs to the NlpA lipoprotein family
PB20LOC_014590	COG1720	tRNA m6t6A37 methyltransferase activity
PB20LOC_014595	COG0442	prolyl-tRNA aminoacylation
PB20LOC_014605	COG1388	LysM domain
PB20LOC_014605	COG4942	peptidase
PB20LOC_014610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PB20LOC_014615	COG0585	pseudouridine synthase activity
PB20LOC_014620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PB20LOC_014625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PB20LOC_014630	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PB20LOC_014640	COG0765	amino acid transport
PB20LOC_014645	COG1126	abc transporter atp-binding protein
PB20LOC_014655	COG0529	Catalyzes the synthesis of activated sulfate
PB20LOC_014660	COG2895	sulfate adenylyltransferase (ATP) activity
PB20LOC_014665	COG0175	sulfate reduction
PB20LOC_014670	COG1648	precorrin-2 dehydrogenase activity
PB20LOC_014670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PB20LOC_014675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB20LOC_014680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PB20LOC_014690	COG2723	6-phospho-beta-galactosidase activity
PB20LOC_014695	COG1609	Transcriptional regulator
PB20LOC_014700	COG0175	sulfate reduction
PB20LOC_014705	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PB20LOC_014710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PB20LOC_014720	COG2200	EAL domain
PB20LOC_014725	COG0720	synthase
PB20LOC_014730	COG0602	queuosine metabolic process
PB20LOC_014735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PB20LOC_014770	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
PB20LOC_014780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PB20LOC_014790	COG0148	phosphopyruvate hydratase activity
PB20LOC_014795	COG0504	CTP synthase activity
PB20LOC_014800	COG3956	TIGRFAM MazG family protein
PB20LOC_014805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PB20LOC_014810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PB20LOC_014820	COG1929	Belongs to the glycerate kinase type-1 family
PB20LOC_014825	COG2084	Dehydrogenase
PB20LOC_014835	COG4948	Mandelate Racemase Muconate Lactonizing
PB20LOC_014840	COG4948	Mandelate Racemase Muconate Lactonizing
PB20LOC_014845	COG2271	Major facilitator Superfamily
PB20LOC_014850	COG2721	sulfolactate sulfo-lyase activity
PB20LOC_014855	COG0840	transmembrane signaling receptor activity
PB20LOC_014865	COG3530	Putative quorum-sensing-regulated virulence factor
PB20LOC_014870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PB20LOC_014875	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PB20LOC_014875	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PB20LOC_014880	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PB20LOC_014885	COG3025	triphosphatase activity
PB20LOC_014890	COG4991	sh3 domain protein
PB20LOC_014895	COG0617	tRNA 3'-terminal CCA addition
PB20LOC_014900	COG1968	undecaprenyl-diphosphatase activity
PB20LOC_014905	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PB20LOC_014910	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PB20LOC_014915	COG0840	transmembrane signaling receptor activity
PB20LOC_014920	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PB20LOC_014925	COG2105	PFAM AIG2 family protein
PB20LOC_014930	COG2911	Protein conserved in bacteria
PB20LOC_014935	COG0729	surface antigen
PB20LOC_014940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PB20LOC_014945	COG1253	flavin adenine dinucleotide binding
PB20LOC_014955	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
PB20LOC_014960	COG1218	3'(2'),5'-bisphosphate nucleotidase
PB20LOC_014965	COG0737	Belongs to the 5'-nucleotidase family
PB20LOC_014980	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
PB20LOC_014985	COG0545	Peptidyl-prolyl cis-trans isomerase
PB20LOC_014990	COG3061	Opacity-associated protein A
PB20LOC_015000	COG0359	binds to the 23S rRNA
PB20LOC_015005	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PB20LOC_015010	COG2965	DNA replication, synthesis of RNA primer
PB20LOC_015015	COG0360	Binds together with S18 to 16S ribosomal RNA
PB20LOC_015020	COG1073	alpha beta
PB20LOC_015025	COG0840	transmembrane signaling receptor activity
PB20LOC_015030	COG1690	Belongs to the RtcB family
PB20LOC_015035	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PB20LOC_015040	COG3766	membrane
PB20LOC_015045	COG0840	transmembrane signaling receptor activity
PB20LOC_015050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PB20LOC_015055	COG0557	exoribonuclease II activity
PB20LOC_015060	COG1959	2 iron, 2 sulfur cluster binding
PB20LOC_015065	COG0840	transmembrane signaling receptor activity
PB20LOC_015075	COG2805	Type II/IV secretion system protein
PB20LOC_015080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PB20LOC_015085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PB20LOC_015090	COG0762	integral membrane protein
PB20LOC_015095	COG1872	DUF167
PB20LOC_015100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PB20LOC_015105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PB20LOC_015120	COG2153	protein acetylation
PB20LOC_015125	COG0477	Major facilitator Superfamily
PB20LOC_015130	COG0204	Acyl-transferase
PB20LOC_015130	COG0318	PFAM AMP-dependent synthetase and ligase
PB20LOC_015135	COG0840	transmembrane signaling receptor activity
PB20LOC_015145	COG1609	Transcriptional regulator
PB20LOC_015150	COG3835	regulator
PB20LOC_015160	COG1929	Belongs to the glycerate kinase type-1 family
PB20LOC_015165	COG2610	gluconate transmembrane transporter activity
PB20LOC_015175	COG0583	DNA-binding transcription factor activity
PB20LOC_015180	COG0583	DNA-binding transcription factor activity
PB20LOC_015200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PB20LOC_015210	COG2124	cytochrome p450
PB20LOC_015225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PB20LOC_015235	COG1522	sequence-specific DNA binding
PB20LOC_015245	COG1448	Aminotransferase
PB20LOC_015250	COG1451	nucleotide metabolic process
PB20LOC_015330	COG1203	CRISPR-associated helicase, Cas3
PB20LOC_015335	COG1518	maintenance of DNA repeat elements
PB20LOC_015340	COG0432	Pfam Uncharacterised protein family UPF0047
PB20LOC_015350	COG0629	single-stranded DNA binding
PB20LOC_015370	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PB20LOC_015390	COG0395	ABC-type sugar transport system, permease component
PB20LOC_015395	COG1175	transmembrane transport
PB20LOC_015400	COG3842	ATPase activity
PB20LOC_015405	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
PB20LOC_015425	COG2971	BadF BadG BcrA BcrD
PB20LOC_015435	COG1121	(ABC) transporter
PB20LOC_015440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PB20LOC_015445	COG0803	Belongs to the bacterial solute-binding protein 9 family
PB20LOC_015460	COG4245	von Willebrand factor, type A
PB20LOC_015475	COG4245	von Willebrand factor, type A
PB20LOC_015490	COG1358	cellular component organization or biogenesis
PB20LOC_015545	COG1349	DNA-binding transcription factor activity
PB20LOC_015550	COG1414	Transcriptional regulator
PB20LOC_015555	COG2610	gluconate transmembrane transporter activity
PB20LOC_015560	COG0129	dihydroxy-acid dehydratase activity
PB20LOC_015565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PB20LOC_015570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PB20LOC_015575	COG3395	kinase activity
PB20LOC_015580	COG1454	alcohol dehydrogenase
PB20LOC_015585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PB20LOC_015600	COG2731	YhcH YjgK YiaL family protein
PB20LOC_015605	COG1028	Short-chain dehydrogenase reductase Sdr
PB20LOC_015610	COG1882	Formate acetyltransferase
PB20LOC_015615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PB20LOC_015630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PB20LOC_015635	COG1940	carbohydrate kinase activity
PB20LOC_015640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PB20LOC_015650	COG1172	Belongs to the binding-protein-dependent transport system permease family
PB20LOC_015655	COG1129	ABC transporter
PB20LOC_015665	COG1349	DNA-binding transcription factor activity
PB20LOC_015670	COG3112	Uncharacterised protein family (UPF0231)
PB20LOC_015675	COG4592	Periplasmic binding protein
PB20LOC_015680	COG0477	Major facilitator Superfamily
PB20LOC_015685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB20LOC_015690	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB20LOC_015695	COG1120	ATPase activity
PB20LOC_015710	COG2382	esterase
PB20LOC_015715	COG4774	siderophore transport
PB20LOC_015720	COG3433	isochorismatase activity
PB20LOC_015720	COG1535	isochorismatase
PB20LOC_015740	COG0640	Transcriptional regulator
PB20LOC_015745	COG4771	TonB-dependent receptor
PB20LOC_015750	COG2207	Transcriptional regulator
PB20LOC_015755	COG2079	MmgE PrpD family protein
PB20LOC_015765	COG1073	alpha beta
PB20LOC_015780	COG0583	DNA-binding transcription factor activity
PB20LOC_015785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PB20LOC_015790	COG0508	dehydrogenase complex catalyzes the overall conversion of
PB20LOC_015795	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PB20LOC_015805	COG1113	amino acid transport
PB20LOC_015810	COG3725	Membrane protein required for beta-lactamase induction
PB20LOC_015815	COG3023	N-Acetylmuramoyl-L-alanine amidase
PB20LOC_015820	COG3248	Nucleoside-binding outer membrane protein
PB20LOC_015825	COG0157	Belongs to the NadC ModD family
PB20LOC_015830	COG4969	Belongs to the N-Me-Phe pilin family
PB20LOC_015835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PB20LOC_015840	COG1459	type II secretion system
PB20LOC_015845	COG0516	GMP reductase activity
PB20LOC_015850	COG0237	dephospho-CoA kinase activity
PB20LOC_015855	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
PB20LOC_015860	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PB20LOC_015865	COG0494	nUDIX hydrolase
PB20LOC_015870	COG0653	protein targeting
PB20LOC_015885	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PB20LOC_015890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PB20LOC_015895	COG0849	cell division
PB20LOC_015900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PB20LOC_015905	COG1181	Belongs to the D-alanine--D-alanine ligase family
PB20LOC_015910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PB20LOC_015915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PB20LOC_015920	COG0772	Belongs to the SEDS family
PB20LOC_015925	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PB20LOC_015930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PB20LOC_015935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PB20LOC_015940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PB20LOC_015945	COG0768	penicillin binding
PB20LOC_015950	COG3116	cell division
PB20LOC_015955	COG0275	rRNA processing
PB20LOC_015960	COG2001	Belongs to the MraZ family
PB20LOC_015980	COG0028	Belongs to the TPP enzyme family
PB20LOC_015985	COG1022	Amp-dependent synthetase and ligase
PB20LOC_015990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PB20LOC_015995	COG0473	3-isopropylmalate dehydrogenase activity
PB20LOC_016000	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PB20LOC_016005	COG0066	3-isopropylmalate dehydratase activity
PB20LOC_016025	COG0840	transmembrane signaling receptor activity
PB20LOC_016040	COG4533	DNA binding
PB20LOC_016055	COG4143	(ABC) transporter
PB20LOC_016060	COG1178	ABC-type Fe3 transport system permease component
PB20LOC_016065	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
PB20LOC_016070	COG3507	Belongs to the glycosyl hydrolase 43 family
PB20LOC_016075	COG0028	Belongs to the TPP enzyme family
PB20LOC_016080	COG0440	acetolactate synthase activity
PB20LOC_016085	COG0586	Pfam SNARE associated Golgi protein
PB20LOC_016110	COG0417	DNA replication proofreading
PB20LOC_016115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PB20LOC_016150	COG0564	pseudouridine synthase activity
PB20LOC_016155	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PB20LOC_016160	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PB20LOC_016165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PB20LOC_016170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PB20LOC_016175	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PB20LOC_016180	COG2967	ApaG domain
PB20LOC_016185	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PB20LOC_016195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PB20LOC_016200	COG3610	response to peptide
PB20LOC_016205	COG2966	Psort location CytoplasmicMembrane, score
PB20LOC_016215	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PB20LOC_016220	COG0505	Belongs to the CarA family
PB20LOC_016225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PB20LOC_016230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PB20LOC_016235	COG1047	Peptidyl-prolyl cis-trans
PB20LOC_016245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PB20LOC_016250	COG0196	riboflavin kinase activity
PB20LOC_016255	COG0268	Binds directly to 16S ribosomal RNA
PB20LOC_016260	COG0583	DNA-binding transcription factor activity
PB20LOC_016265	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PB20LOC_016270	COG0484	heat shock protein binding
PB20LOC_016275	COG0443	Heat shock 70 kDa protein
PB20LOC_016280	COG1584	GPR1 FUN34 yaaH family protein
PB20LOC_016290	COG0521	Mo-molybdopterin cofactor biosynthetic process
PB20LOC_016300	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PB20LOC_016305	COG3022	response to hydroperoxide
PB20LOC_016315	COG0083	homoserine kinase activity
PB20LOC_016335	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
PB20LOC_016340	COG0745	RESPONSE REGULATOR receiver
PB20LOC_016345	COG3045	CreA protein
PB20LOC_016350	COG2207	Transcriptional regulator
PB20LOC_016350	COG3708	Transcriptional regulator
PB20LOC_016360	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
PB20LOC_016365	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
PB20LOC_016370	COG0741	lytic transglycosylase activity
PB20LOC_016375	COG0488	(ABC) transporter
PB20LOC_016380	COG0840	transmembrane signaling receptor activity
PB20LOC_016385	COG0604	alcohol dehydrogenase
PB20LOC_016390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PB20LOC_016395	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PB20LOC_016400	COG0583	DNA-binding transcription factor activity
PB20LOC_016420	COG1279	arginine transmembrane transporter activity
PB20LOC_016425	COG1414	Transcriptional regulator
PB20LOC_016430	COG1129	ABC transporter
PB20LOC_016435	COG1172	Belongs to the binding-protein-dependent transport system permease family
PB20LOC_016455	COG2731	YhcH YjgK YiaL family protein
PB20LOC_016465	COG1070	Carbohydrate kinase
PB20LOC_016470	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
PB20LOC_016475	COG3623	hexulose-6-phosphate isomerase
PB20LOC_016480	COG0235	Class ii aldolase
PB20LOC_016485	COG0668	transmembrane transport
PB20LOC_016490	COG0191	fructose-bisphosphate aldolase activity
PB20LOC_016495	COG0126	phosphoglycerate kinase activity
PB20LOC_016500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PB20LOC_016505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PB20LOC_016510	COG0501	Belongs to the peptidase M48B family
PB20LOC_016520	COG1166	arginine decarboxylase activity
PB20LOC_016530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PB20LOC_016535	COG3091	SprT-like family
PB20LOC_016540	COG2356	endonuclease I
PB20LOC_016545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PB20LOC_016550	COG0189	ligase activity
PB20LOC_016555	COG1678	Uncharacterized ACR, COG1678
PB20LOC_016560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PB20LOC_016565	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PB20LOC_016570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PB20LOC_016575	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PB20LOC_016580	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
PB20LOC_016585	COG0330	HflC and HflK could
PB20LOC_016590	COG0330	HflC and HflK could
PB20LOC_016595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PB20LOC_016600	COG1923	regulation of RNA biosynthetic process
PB20LOC_016605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PB20LOC_016610	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PB20LOC_016615	COG0860	N-Acetylmuramoyl-L-alanine amidase
PB20LOC_016620	COG0802	atpase or kinase
PB20LOC_016625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PB20LOC_016625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PB20LOC_016630	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PB20LOC_016645	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PB20LOC_016670	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PB20LOC_016675	COG1162	GTPase activity
PB20LOC_016680	COG0688	phosphatidylethanolamine metabolic process
PB20LOC_016685	COG1511	domain protein
PB20LOC_016685	COG3264	Mechanosensitive ion channel
PB20LOC_016690	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
PB20LOC_016695	COG1053	succinate dehydrogenase
PB20LOC_016700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PB20LOC_016705	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
PB20LOC_016710	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
PB20LOC_016715	COG3040	lipid binding
PB20LOC_016730	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PB20LOC_016735	COG1509	lysine 2,3-aminomutase activity
PB20LOC_016745	COG0166	Belongs to the GPI family
PB20LOC_016750	COG0527	aspartate kinase activity
PB20LOC_016760	COG0471	metal ion transport
PB20LOC_016770	COG0646	methionine synthase
PB20LOC_016770	COG1410	methionine synthase
PB20LOC_016775	COG1414	Transcriptional regulator
PB20LOC_016790	COG4589	Belongs to the CDS family
PB20LOC_016795	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PB20LOC_016805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PB20LOC_016810	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
PB20LOC_016845	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PB20LOC_016855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PB20LOC_016860	COG0009	L-threonylcarbamoyladenylate synthase
PB20LOC_016865	COG0551	DNA topoisomerase type I activity
PB20LOC_016870	COG2922	Belongs to the Smg family
PB20LOC_016875	COG0758	DNA mediated transformation
PB20LOC_016880	COG0242	peptide deformylase activity
PB20LOC_016885	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PB20LOC_016890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PB20LOC_016890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PB20LOC_016895	COG0569	domain protein
PB20LOC_016900	COG1970	mechanosensitive ion channel activity
PB20LOC_016905	COG3036	rescue of stalled ribosome
PB20LOC_016910	COG0203	ribosomal protein L17
PB20LOC_016915	COG0202	RNA polymerase activity
PB20LOC_016920	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PB20LOC_016930	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PB20LOC_016935	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PB20LOC_016940	COG0201	protein transport
PB20LOC_016945	COG0200	Binds to the 23S rRNA
PB20LOC_016950	COG1841	ribosomal large subunit assembly
PB20LOC_016955	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PB20LOC_016960	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PB20LOC_016965	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PB20LOC_016970	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PB20LOC_016975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PB20LOC_016980	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PB20LOC_016985	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PB20LOC_016995	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PB20LOC_017000	COG0255	Belongs to the universal ribosomal protein uL29 family
PB20LOC_017005	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PB20LOC_017010	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PB20LOC_017015	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PB20LOC_017020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PB20LOC_017025	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PB20LOC_017035	COG0088	Forms part of the polypeptide exit tunnel
PB20LOC_017040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PB20LOC_017045	COG0051	transcription antitermination factor activity, RNA binding
PB20LOC_017050	COG2193	ferroxidase activity
PB20LOC_017060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PB20LOC_017065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PB20LOC_017070	COG0049	tRNA binding
PB20LOC_017075	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PB20LOC_017080	COG2168	tRNA wobble position uridine thiolation
PB20LOC_017085	COG2923	Belongs to the DsrF TusC family
PB20LOC_017090	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PB20LOC_017095	COG2964	Protein conserved in bacteria
PB20LOC_017100	COG2194	sulfuric ester hydrolase activity
PB20LOC_017105	COG0745	RESPONSE REGULATOR receiver
PB20LOC_017110	COG0642	Histidine kinase
PB20LOC_017115	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PB20LOC_017130	COG0545	Peptidyl-prolyl cis-trans isomerase
PB20LOC_017135	COG2900	Belongs to the SlyX family
PB20LOC_017140	COG1047	Peptidyl-prolyl cis-trans
PB20LOC_017145	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PB20LOC_017150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PB20LOC_017150	COG0475	glutathione-regulated potassium exporter activity
PB20LOC_017155	COG2249	NAD(P)H dehydrogenase (quinone) activity
PB20LOC_017160	COG0488	(ABC) transporter
PB20LOC_017170	COG0429	hydrolase of the alpha beta-hydrolase fold
PB20LOC_017175	COG3089	Belongs to the UPF0270 family
PB20LOC_017180	COG3954	Phosphoribulokinase
PB20LOC_017185	COG1765	OsmC-like protein
PB20LOC_017190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PB20LOC_017210	COG3866	Pectate lyase
PB20LOC_017225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PB20LOC_017230	COG4608	Belongs to the ABC transporter superfamily
PB20LOC_017235	COG0444	Belongs to the ABC transporter superfamily
PB20LOC_017240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB20LOC_017245	COG0601	transmembrane transport
PB20LOC_017250	COG0747	negative chemotaxis
PB20LOC_017255	COG4948	Mandelate Racemase Muconate Lactonizing
PB20LOC_017260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PB20LOC_017270	COG1648	precorrin-2 dehydrogenase activity
PB20LOC_017270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PB20LOC_017295	COG1473	amidohydrolase
PB20LOC_017305	COG0546	phosphoglycolate phosphatase activity
PB20LOC_017310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PB20LOC_017325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PB20LOC_017330	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PB20LOC_017335	COG4796	Type ii and iii secretion system protein
PB20LOC_017360	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PB20LOC_017365	COG0494	nUDIX hydrolase
PB20LOC_017375	COG1011	Hydrolase
PB20LOC_017380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PB20LOC_017385	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PB20LOC_017390	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PB20LOC_017410	COG2814	Major facilitator Superfamily
PB20LOC_017415	COG4774	siderophore transport
PB20LOC_017430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PB20LOC_017440	COG0840	transmembrane signaling receptor activity
PB20LOC_017450	COG2972	Histidine kinase
PB20LOC_017455	COG1917	Cupin 2, conserved barrel domain protein
PB20LOC_017455	COG2207	Transcriptional regulator
PB20LOC_017460	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PB20LOC_017465	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PB20LOC_017475	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PB20LOC_017480	COG1882	Formate acetyltransferase
PB20LOC_017485	COG0693	protein deglycase activity
PB20LOC_017495	COG1012	belongs to the aldehyde dehydrogenase family
PB20LOC_017510	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PB20LOC_017520	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
PB20LOC_017530	COG4869	propanediol catabolic process
PB20LOC_017540	COG2183	response to ionizing radiation
PB20LOC_017545	COG1414	Transcriptional regulator
PB20LOC_017590	COG1785	Belongs to the alkaline phosphatase family
PB20LOC_017595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PB20LOC_017600	COG2267	carboxylic ester hydrolase activity
PB20LOC_017605	COG1040	competence protein
PB20LOC_017610	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PB20LOC_017610	COG0316	Belongs to the HesB IscA family
PB20LOC_017615	COG1640	4-alpha-glucanotransferase
PB20LOC_017620	COG0058	SHG alpha-glucan phosphorylase activity
PB20LOC_017625	COG1349	DNA-binding transcription factor activity
PB20LOC_017630	COG0705	Rhomboid family
PB20LOC_017635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PB20LOC_017640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PB20LOC_017645	COG2731	YhcH YjgK YiaL family protein
PB20LOC_017650	COG2271	Major facilitator Superfamily
PB20LOC_017655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PB20LOC_017660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PB20LOC_017665	COG0058	SHG alpha-glucan phosphorylase activity
PB20LOC_017670	COG0058	SHG alpha-glucan phosphorylase activity
PB20LOC_017675	COG0297	glycogen (starch) synthase activity
PB20LOC_017680	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PB20LOC_017685	COG1523	belongs to the glycosyl hydrolase 13 family
PB20LOC_017690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PB20LOC_017695	COG3275	phosphorelay sensor kinase activity
PB20LOC_017705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PB20LOC_017710	COG2095	MarC family integral membrane protein
PB20LOC_017715	COG1472	Belongs to the glycosyl hydrolase 3 family
PB20LOC_017720	COG1741	Belongs to the pirin family
PB20LOC_017735	COG0247	lactate metabolic process
PB20LOC_017740	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
PB20LOC_017745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PB20LOC_017750	COG2271	Major facilitator Superfamily
PB20LOC_017755	COG0561	phosphatase activity
PB20LOC_017760	COG2267	carboxylic ester hydrolase activity
PB20LOC_017765	COG1280	lysine exporter protein (LysE YggA)
PB20LOC_017770	COG1280	lysine exporter protein (LysE YggA)
PB20LOC_017775	COG0514	ATP-dependent DNA helicase (RecQ)
PB20LOC_017785	COG2050	protein possibly involved in aromatic compounds catabolism
PB20LOC_017795	COG3180	Ammonia monooxygenase
PB20LOC_017800	COG0598	Magnesium transport protein CorA
PB20LOC_017805	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PB20LOC_017815	COG0210	DNA helicase
PB20LOC_017820	COG1011	Hydrolase
PB20LOC_017835	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PB20LOC_017845	COG1965	Belongs to the frataxin family
PB20LOC_017860	COG0181	hydroxymethylbilane synthase activity
PB20LOC_017865	COG1587	Uroporphyrinogen-III synthase
PB20LOC_017870	COG2959	enzyme of heme biosynthesis
PB20LOC_017875	COG3071	HemY protein
PB20LOC_017880	COG1802	Transcriptional regulator
PB20LOC_017900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB20LOC_017905	COG4597	amino acid ABC transporter
PB20LOC_017910	COG0765	amino acid transport
PB20LOC_017915	COG1126	abc transporter atp-binding protein
PB20LOC_017920	COG1473	amidohydrolase
PB20LOC_017925	COG1126	abc transporter atp-binding protein
PB20LOC_017930	COG0765	amino acid transport
PB20LOC_017935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB20LOC_017940	COG0456	acetyltransferase
PB20LOC_017945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PB20LOC_017960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB20LOC_017985	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PB20LOC_017995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PB20LOC_018000	COG2244	polysaccharide biosynthetic process
PB20LOC_018005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PB20LOC_018010	COG0456	acetyltransferase
PB20LOC_018015	COG1088	dTDP-glucose 4,6-dehydratase activity
PB20LOC_018020	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PB20LOC_018025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PB20LOC_018030	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
PB20LOC_018035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PB20LOC_018040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PB20LOC_018045	COG3118	belongs to the thioredoxin family
PB20LOC_018050	COG0513	Belongs to the DEAD box helicase family
PB20LOC_018055	COG0248	Ppx GppA phosphatase
PB20LOC_018065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PB20LOC_018070	COG0506	proline dehydrogenase activity
PB20LOC_018070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PB20LOC_018070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PB20LOC_018075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PB20LOC_018080	COG0583	DNA-binding transcription factor activity
PB20LOC_018090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PB20LOC_018095	COG0583	DNA-binding transcription factor activity
PB20LOC_018115	COG0129	dihydroxy-acid dehydratase activity
PB20LOC_018120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PB20LOC_018125	COG3978	acetolactate synthase activity
PB20LOC_018145	COG3085	chromosome segregation
PB20LOC_018150	COG0583	DNA-binding transcription factor activity
PB20LOC_018155	COG1172	Belongs to the binding-protein-dependent transport system permease family
PB20LOC_018160	COG1172	Belongs to the binding-protein-dependent transport system permease family
PB20LOC_018165	COG1129	ABC transporter
PB20LOC_018170	COG1879	ABC-type sugar transport system periplasmic component
PB20LOC_018215	COG1739	Uncharacterized protein family UPF0029
PB20LOC_018220	COG0006	proline dipeptidase activity
PB20LOC_018225	COG1024	Enoyl-CoA hydratase
PB20LOC_018225	COG1250	3-hydroxyacyl-CoA dehydrogenase
PB20LOC_018230	COG0183	Belongs to the thiolase family
PB20LOC_018245	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PB20LOC_018250	COG0250	Participates in transcription elongation, termination and antitermination
PB20LOC_018260	COG0084	hydrolase, TatD family'
PB20LOC_018265	COG0805	protein transport
PB20LOC_018270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PB20LOC_018275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PB20LOC_018280	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PB20LOC_018290	COG2226	methyltransferase
PB20LOC_018295	COG1322	Protein conserved in bacteria
PB20LOC_018300	COG0165	Argininosuccinate lyase
PB20LOC_018305	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PB20LOC_018310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PB20LOC_018315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PB20LOC_018320	COG2188	Transcriptional regulator
PB20LOC_018325	COG4948	Mandelate Racemase Muconate Lactonizing
PB20LOC_018330	COG2190	(PTS) system
PB20LOC_018330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PB20LOC_018330	COG1263	PTS System
PB20LOC_018340	COG3501	Rhs element vgr protein
PB20LOC_018510	COG5444	nuclease activity
PB20LOC_018525	COG3209	COG3209 Rhs family protein
PB20LOC_018530	COG3209	COG3209 Rhs family protein
PB20LOC_018555	COG3209	COG3209 Rhs family protein
PB20LOC_018590	COG3209	COG3209 Rhs family protein
PB20LOC_018750	COG0583	DNA-binding transcription factor activity
PB20LOC_018790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PB20LOC_018795	COG1116	anion transmembrane transporter activity
PB20LOC_018870	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PB20LOC_018885	COG0412	Dienelactone hydrolase
PB20LOC_018890	COG0840	transmembrane signaling receptor activity
PB20LOC_018895	COG0840	transmembrane signaling receptor activity
PB20LOC_018900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PB20LOC_018905	COG0583	DNA-binding transcription factor activity
PB20LOC_018925	COG1045	serine acetyltransferase
PB20LOC_018930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PB20LOC_018935	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PB20LOC_018940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PB20LOC_018945	COG4942	peptidase
PB20LOC_018950	COG2861	carbohydrate metabolic process
PB20LOC_018955	COG1063	alcohol dehydrogenase
PB20LOC_018960	COG0156	8-amino-7-oxononanoate synthase activity
PB20LOC_018965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PB20LOC_018975	COG0859	PFAM glycosyl transferase family 9
PB20LOC_018980	COG3307	-O-antigen
PB20LOC_018985	COG0859	PFAM glycosyl transferase family 9
PB20LOC_018990	COG0438	transferase activity, transferring glycosyl groups
PB20LOC_018995	COG0515	serine threonine protein kinase
PB20LOC_019000	COG0438	transferase activity, transferring glycosyl groups
PB20LOC_019010	COG1442	glycosyl transferase family 8
PB20LOC_019015	COG0438	transferase activity, transferring glycosyl groups
PB20LOC_019015	COG4641	Protein conserved in bacteria
PB20LOC_019020	COG0110	maltose O-acetyltransferase activity
PB20LOC_019025	COG1218	3'(2'),5'-bisphosphate nucleotidase
PB20LOC_019030	COG2089	acid synthase
PB20LOC_019045	COG1519	Transferase
PB20LOC_019050	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PB20LOC_019060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PB20LOC_019070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PB20LOC_019075	COG2003	Belongs to the UPF0758 family
PB20LOC_019080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PB20LOC_019085	COG0756	dUTP diphosphatase activity
PB20LOC_019090	COG1309	transcriptional regulator
PB20LOC_019095	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PB20LOC_019100	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PB20LOC_019105	COG4948	Mandelate Racemase Muconate Lactonizing
PB20LOC_019110	COG4172	Belongs to the ABC transporter superfamily
PB20LOC_019115	COG0747	negative chemotaxis
PB20LOC_019120	COG0601	transmembrane transport
PB20LOC_019125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB20LOC_019140	COG1446	asparaginase
PB20LOC_019145	COG0583	DNA-binding transcription factor activity
PB20LOC_019150	COG1561	YicC-like family, N-terminal region
PB20LOC_019175	COG3423	Transcriptional regulator
PB20LOC_019205	COG0628	permease
PB20LOC_019210	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PB20LOC_019210	COG0456	acetyltransferase
PB20LOC_019215	COG1304	FMN binding
PB20LOC_019220	COG1012	belongs to the aldehyde dehydrogenase family
PB20LOC_019230	COG3239	Fatty acid desaturase
PB20LOC_019260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PB20LOC_019265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PB20LOC_019270	COG3136	membrane protein required for alginate biosynthesis
PB20LOC_019285	COG4677	pectinesterase activity
PB20LOC_019290	COG2771	luxR family
PB20LOC_019295	COG3916	Acyl-homoserine-lactone synthase
PB20LOC_019300	COG0137	argininosuccinate synthase activity
PB20LOC_019310	COG1609	Transcriptional regulator
PB20LOC_019310	COG2207	Transcriptional regulator
PB20LOC_019315	COG4214	carbohydrate transport
PB20LOC_019320	COG1129	ABC transporter
PB20LOC_019325	COG4213	ABC transporter substrate-binding protein
PB20LOC_019330	COG2115	Belongs to the xylose isomerase family
PB20LOC_019335	COG1070	Carbohydrate kinase
PB20LOC_019340	COG3274	enterobacterial common antigen metabolic process
PB20LOC_019345	COG1012	belongs to the aldehyde dehydrogenase family
PB20LOC_019350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PB20LOC_019355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PB20LOC_019360	COG0840	transmembrane signaling receptor activity
PB20LOC_019370	COG3722	fumarate hydratase activity
PB20LOC_019375	COG0246	Mannitol dehydrogenase
PB20LOC_019380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB20LOC_019380	COG2213	PTS system mannitol-specific
PB20LOC_019390	COG0751	glycine-tRNA ligase activity
PB20LOC_019395	COG0752	glycyl-tRNA synthetase alpha subunit
PB20LOC_019400	COG0730	response to heat
PB20LOC_019405	COG2818	Glycosylase
PB20LOC_019410	COG0456	acetyltransferase
PB20LOC_019415	COG0840	transmembrane signaling receptor activity
PB20LOC_019420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PB20LOC_019425	COG4166	transmembrane transport
PB20LOC_019435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB20LOC_019440	COG4172	Belongs to the ABC transporter superfamily
PB20LOC_019445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PB20LOC_019460	COG3479	Phenolic acid decarboxylase
PB20LOC_019465	COG0583	DNA-binding transcription factor activity
PB20LOC_019470	COG1280	lysine exporter protein (LysE YggA)
PB20LOC_019500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PB20LOC_019505	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PB20LOC_019515	COG2214	Heat shock protein DnaJ domain protein
PB20LOC_019520	COG0443	Heat shock 70 kDa protein
PB20LOC_019545	COG0742	ribosomal rna small subunit methyltransferase
PB20LOC_019550	COG0737	Belongs to the 5'-nucleotidase family
PB20LOC_019560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PB20LOC_019565	COG0589	response to stress
PB20LOC_019575	COG0306	phosphate transporter
PB20LOC_019580	COG2081	HI0933 family
PB20LOC_019585	COG2200	EAL domain
PB20LOC_019600	COG2194	sulfuric ester hydrolase activity
PB20LOC_019605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PB20LOC_019610	COG0194	GDP metabolic process
PB20LOC_019615	COG1758	RNA polymerase activity
PB20LOC_019620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PB20LOC_019625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PB20LOC_019630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PB20LOC_019635	COG2233	PERMEase
PB20LOC_019640	COG2982	Protein involved in outer membrane biogenesis
PB20LOC_019645	COG0456	acetyltransferase
PB20LOC_019650	COG1490	D-aminoacyl-tRNA deacylase activity
PB20LOC_019655	COG1011	Hydrolase
PB20LOC_019670	COG3852	Histidine kinase
PB20LOC_019695	COG0633	Ferredoxin
PB20LOC_019715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PB20LOC_019720	COG3078	GTPase activator activity
PB20LOC_019725	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PB20LOC_019730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PB20LOC_019730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PB20LOC_019740	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PB20LOC_019745	COG3084	Protein conserved in bacteria
PB20LOC_019750	COG0746	molybdenum cofactor guanylyltransferase activity
PB20LOC_019755	COG1763	Mo-molybdopterin cofactor biosynthetic process
PB20LOC_019785	COG1609	Transcriptional regulator
PB20LOC_019790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PB20LOC_019800	COG1172	Belongs to the binding-protein-dependent transport system permease family
PB20LOC_019805	COG1129	ABC transporter
PB20LOC_019810	COG1869	D-ribose catabolic process
PB20LOC_019815	COG3111	PFAM Bacterial OB fold (BOF) protein
PB20LOC_019825	COG0642	Histidine kinase
PB20LOC_019830	COG3158	transport of potassium into the cell
PB20LOC_019835	COG0714	Associated with various cellular activities
PB20LOC_019840	COG2425	protein containing a von Willebrand factor type A (vWA) domain
PB20LOC_019845	COG2502	aspartate--ammonia ligase
PB20LOC_019850	COG1522	sequence-specific DNA binding
PB20LOC_019855	COG0716	FMN binding
PB20LOC_019860	COG0445	tRNA wobble uridine modification
PB20LOC_019865	COG0357	Ribosomal RNA small subunit methyltransferase G
PB20LOC_019870	COG3312	ion transport
PB20LOC_019875	COG0356	it plays a direct role in the translocation of protons across the membrane
PB20LOC_019885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PB20LOC_019890	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PB20LOC_019895	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PB20LOC_019900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PB20LOC_019905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PB20LOC_019910	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PB20LOC_019935	COG1174	glycine betaine transport
PB20LOC_019950	COG2986	histidine ammonia-lyase
PB20LOC_019960	COG2188	Transcriptional regulator
PB20LOC_019965	COG0402	S-adenosylhomocysteine deaminase activity
PB20LOC_019975	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PB20LOC_019980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PB20LOC_020005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PB20LOC_020010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PB20LOC_020020	COG0318	PFAM AMP-dependent synthetase and ligase
PB20LOC_020025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PB20LOC_020030	COG1216	Glycosyl transferase, family 2
PB20LOC_020055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PB20LOC_020065	COG1028	Short-chain dehydrogenase reductase Sdr
PB20LOC_020080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PB20LOC_020085	COG0573	inorganic phosphate transmembrane transporter activity
PB20LOC_020090	COG0581	inorganic phosphate transmembrane transporter activity
PB20LOC_020095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PB20LOC_020105	COG1396	sequence-specific DNA binding
PB20LOC_020110	COG3135	benzoate transporter
PB20LOC_020115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB20LOC_020120	COG0765	amino acid transport
PB20LOC_020125	COG0765	amino acid transport
PB20LOC_020130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PB20LOC_020135	COG2252	PERMEase
PB20LOC_020140	COG2091	lysine biosynthetic process via aminoadipic acid
PB20LOC_020145	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PB20LOC_020150	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PB20LOC_020150	COG0493	'glutamate synthase
PB20LOC_020175	COG2199	diguanylate cyclase activity
PB20LOC_020185	COG0457	Tetratricopeptide repeat
PB20LOC_020190	COG0726	polysaccharide deacetylase
PB20LOC_020190	COG1649	PFAM Uncharacterised BCR, COG1649
PB20LOC_020195	COG1215	transferase activity, transferring glycosyl groups
PB20LOC_020205	COG1733	regulation of RNA biosynthetic process
PB20LOC_020210	COG0702	epimerase
PB20LOC_020220	COG1396	sequence-specific DNA binding
PB20LOC_020230	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PB20LOC_020235	COG0706	membrane insertase activity
PB20LOC_020245	COG0594	ribonuclease P activity
PB20LOC_020250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PB20LOC_020255	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PB20LOC_020260	COG0592	DNA-directed DNA polymerase activity
PB20LOC_020265	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PB20LOC_020280	COG0840	transmembrane signaling receptor activity
PB20LOC_020285	COG1609	Transcriptional regulator
PB20LOC_020295	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PB20LOC_020300	COG1447	Phosphotransferase system cellobiose-specific component IIA
PB20LOC_020305	COG2723	6-phospho-beta-galactosidase activity
PB20LOC_020310	COG0561	phosphatase activity
PB20LOC_020325	COG0747	negative chemotaxis
PB20LOC_020330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PB20LOC_020345	COG0601	transmembrane transport
PB20LOC_020350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB20LOC_020360	COG2186	Transcriptional regulator
PB20LOC_020365	COG3734	2-keto-3-deoxy-galactonokinase
PB20LOC_020370	COG0800	Aldolase
PB20LOC_020375	COG4948	Mandelate Racemase Muconate Lactonizing
PB20LOC_020380	COG2271	Major facilitator Superfamily
PB20LOC_020390	COG1116	anion transmembrane transporter activity
PB20LOC_020395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PB20LOC_020400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PB20LOC_020405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PB20LOC_020415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PB20LOC_020415	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PB20LOC_020420	COG2723	6-phospho-beta-galactosidase activity
PB20LOC_020430	COG0823	Involved in the tonB-independent uptake of proteins
PB20LOC_020435	COG5645	(Lipo)protein
PB20LOC_020440	COG0071	Belongs to the small heat shock protein (HSP20) family
PB20LOC_020445	COG0071	Belongs to the small heat shock protein (HSP20) family
PB20LOC_020455	COG0569	domain protein
PB20LOC_020455	COG2985	domain, Protein
PB20LOC_020460	COG0471	metal ion transport
PB20LOC_020465	COG3290	protein histidine kinase activity
PB20LOC_020470	COG4565	transcriptional regulatory protein
PB20LOC_020475	COG3493	citrate carrier protein
PB20LOC_020480	COG0747	negative chemotaxis
PB20LOC_020485	COG0601	transmembrane transport
PB20LOC_020490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PB20LOC_020495	COG0444	Belongs to the ABC transporter superfamily
PB20LOC_020500	COG4608	Belongs to the ABC transporter superfamily
PB20LOC_020545	COG3977	Valine--pyruvate aminotransferase
PB20LOC_020560	COG1063	alcohol dehydrogenase
PB20LOC_020565	COG1802	Transcriptional regulator
PB20LOC_020570	COG2271	Major facilitator Superfamily
PB20LOC_020585	COG3118	belongs to the thioredoxin family
PB20LOC_020585	COG0457	Tetratricopeptide repeat
PB20LOC_020590	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
PB20LOC_020595	COG1215	transferase activity, transferring glycosyl groups
PB20LOC_020600	COG1215	transferase activity, transferring glycosyl groups
PB20LOC_020630	COG2200	EAL domain
PB20LOC_020630	COG2199	diguanylate cyclase activity
PB20LOC_020635	COG1301	dicarboxylic acid transport
PB20LOC_020640	COG0612	Peptidase, M16
PB20LOC_020645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PB20LOC_020650	COG1295	ribonuclease BN
PB20LOC_020655	COG0477	Major facilitator Superfamily
PB20LOC_020665	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PB20LOC_020670	COG0425	Belongs to the sulfur carrier protein TusA family
PB20LOC_020680	COG3714	YhhN family
PB20LOC_020690	COG3776	membrane
PB20LOC_020695	COG0742	ribosomal rna small subunit methyltransferase
PB20LOC_020700	COG0552	protein localization to endoplasmic reticulum
PB20LOC_020705	COG2884	Cell division ATP-binding protein ftsE
PB20LOC_020710	COG2177	Part of the ABC transporter FtsEX involved in
PB20LOC_020725	COG0683	leucine binding
PB20LOC_020730	COG0559	Belongs to the binding-protein-dependent transport system permease family
PB20LOC_020735	COG4177	L-phenylalanine transmembrane transporter activity
PB20LOC_020740	COG0411	ABC transporter
PB20LOC_020745	COG0410	ABC transporter
PB20LOC_020750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PB20LOC_020755	COG0840	transmembrane signaling receptor activity
PB20LOC_020760	COG0840	transmembrane signaling receptor activity
PB20LOC_020765	COG0840	transmembrane signaling receptor activity
PB20LOC_020775	COG2610	gluconate transmembrane transporter activity
PB20LOC_020780	COG3622	Belongs to the hyi family
PB20LOC_020785	COG0235	Class ii aldolase
PB20LOC_020790	COG3395	kinase activity
PB20LOC_020795	COG2084	Dehydrogenase
PB20LOC_020800	COG1349	DNA-binding transcription factor activity
PB20LOC_020815	COG3609	addiction module antidote protein, CC2985 family
PB20LOC_020820	COG1653	transport
PB20LOC_020825	COG1175	transmembrane transport
PB20LOC_020830	COG0395	ABC-type sugar transport system, permease component
PB20LOC_020835	COG3842	ATPase activity
PB20LOC_020840	COG0584	glycerophosphoryl diester phosphodiesterase
PB20LOC_020855	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PB20LOC_020870	COG2205	protein histidine kinase activity
PB20LOC_020875	COG0745	RESPONSE REGULATOR receiver
PB20LOC_020880	COG3678	ATP-independent chaperone mediated protein folding
PB20LOC_020885	COG3831	ATPase activity
PB20LOC_020890	COG0714	Associated with various cellular activities
PB20LOC_020895	COG2425	protein containing a von Willebrand factor type A (vWA) domain
PB20LOC_020900	COG3552	Protein containing von Willebrand factor type A (VWA) domain
PB20LOC_020910	COG2814	Major facilitator Superfamily
PB20LOC_020915	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PB20LOC_020920	COG0205	6-phosphofructokinase activity
PB20LOC_021055	COG4104	PAAR repeat-containing protein
PB20LOC_021055	COG3209	COG3209 Rhs family protein
PB20LOC_021085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PB20LOC_021090	COG2957	Belongs to the agmatine deiminase family
PB20LOC_021095	COG0149	triose-phosphate isomerase activity
PB20LOC_021105	COG3152	Membrane
PB20LOC_021115	COG1494	fructose-1,6-bisphosphatase
PB20LOC_021120	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PB20LOC_021125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PB20LOC_021130	COG3074	FtsZ-dependent cytokinesis
PB20LOC_021135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PB20LOC_021140	COG1575	Belongs to the MenA family. Type 1 subfamily
PB20LOC_021145	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PB20LOC_021150	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PB20LOC_021155	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PB20LOC_021160	COG1609	Transcriptional regulator
PB20LOC_021165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PB20LOC_021170	COG0254	rRNA binding
PB20LOC_021175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB20LOC_021185	COG1120	ATPase activity
PB20LOC_021190	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
PB20LOC_021195	COG0626	cystathionine gamma-synthase activity
PB20LOC_021200	COG0460	homoserine dehydrogenase
PB20LOC_021200	COG0527	aspartate kinase activity
PB20LOC_021215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PB20LOC_021230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PB20LOC_021240	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PB20LOC_021265	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PB20LOC_021270	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PB20LOC_021270	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PB20LOC_021275	COG1072	(Pantothenic acid kinase))
PB20LOC_021300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PB20LOC_021310	COG0250	Participates in transcription elongation, termination and antitermination
PB20LOC_021315	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PB20LOC_021320	COG0081	regulation of translation
PB20LOC_021325	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PB20LOC_021330	COG0222	ribosome binding
PB20LOC_021335	COG0085	RNA polymerase activity
PB20LOC_021340	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PB20LOC_021345	COG0477	Major facilitator Superfamily
PB20LOC_021350	COG5457	Domain of unknown function (DUF1127)
PB20LOC_021355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PB20LOC_021365	COG2022	thiamine diphosphate biosynthetic process
PB20LOC_021370	COG2104	thiamine diphosphate biosynthetic process
PB20LOC_021375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PB20LOC_021380	COG0352	thiamine-phosphate diphosphorylase activity
PB20LOC_021385	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PB20LOC_021390	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
PB20LOC_021395	COG2816	NAD+ diphosphatase activity
PB20LOC_021400	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PB20LOC_021405	COG1515	deoxyribonuclease V activity
PB20LOC_021425	COG0151	Belongs to the GarS family
PB20LOC_021430	COG0138	bifunctional purine biosynthesis protein purh
PB20LOC_021455	COG1126	abc transporter atp-binding protein
PB20LOC_021460	COG0765	amino acid transport
PB20LOC_021465	COG4597	amino acid ABC transporter
PB20LOC_021470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB20LOC_021475	COG0765	amino acid transport
PB20LOC_021480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PB20LOC_021505	COG0582	viral genome integration into host DNA
PB20LOC_021615	COG1802	Transcriptional regulator
PB20LOC_021615	COG4626	Terminase
PB20LOC_021625	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PB20LOC_021640	COG2264	protein methyltransferase activity
PB20LOC_021645	COG4145	pantothenate transmembrane transporter activity
PB20LOC_021650	COG3924	membrane
PB20LOC_021655	COG3585	molybdate ion transport
PB20LOC_021665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PB20LOC_021670	COG1120	ATPase activity
PB20LOC_021675	COG0500	methyltransferase
PB20LOC_021680	COG0157	Belongs to the NadC ModD family
PB20LOC_021690	COG0439	Biotin carboxylase
PB20LOC_021695	COG0511	ligase activity, forming carbon-carbon bonds
PB20LOC_021700	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PB20LOC_021705	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PB20LOC_021710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PB20LOC_021725	COG0604	alcohol dehydrogenase
PB20LOC_021730	COG2199	diguanylate cyclase activity
PB20LOC_021730	COG2200	EAL domain
PB20LOC_021735	COG1077	Cell shape determining protein MreB Mrl
PB20LOC_021740	COG1792	Involved in formation and maintenance of cell shape
PB20LOC_021745	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PB20LOC_021750	COG0424	maF-like protein
PB20LOC_021755	COG1530	ribonuclease E activity
PB20LOC_021760	COG3164	Protein of unknown function
PB20LOC_021765	COG0312	modulator of DNA gyrase
PB20LOC_021770	COG0583	DNA-binding transcription factor activity
PB20LOC_021780	COG1566	PFAM secretion protein HlyD family protein
PB20LOC_021785	COG1289	transmembrane transporter activity
PB20LOC_021790	COG3028	Belongs to the UPF0307 family
PB20LOC_021795	COG0312	modulator of DNA gyrase
PB20LOC_021800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PB20LOC_021805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB20LOC_021810	COG1660	Displays ATPase and GTPase activities
PB20LOC_021820	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PB20LOC_021825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PB20LOC_021830	COG1137	ATPase activity
PB20LOC_021835	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PB20LOC_021840	COG3117	lipopolysaccharide transmembrane transporter activity
PB20LOC_021845	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PB20LOC_021850	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PB20LOC_021850	COG0517	IMP dehydrogenase activity
PB20LOC_021855	COG0530	calcium, potassium:sodium antiporter activity
PB20LOC_021860	COG1127	ABC transporter
PB20LOC_021865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PB20LOC_021870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PB20LOC_021875	COG2854	intermembrane phospholipid transfer
PB20LOC_021880	COG3113	response to antibiotic
PB20LOC_021885	COG5007	Belongs to the BolA IbaG family
PB20LOC_021890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PB20LOC_021895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PB20LOC_021900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PB20LOC_021905	COG3105	Protein conserved in bacteria
PB20LOC_021910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PB20LOC_021915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PB20LOC_021920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PB20LOC_021925	COG0625	glutathione transferase activity
PB20LOC_021930	COG2969	positive regulation of protein catabolic process
PB20LOC_021940	COG0493	'glutamate synthase
PB20LOC_021945	COG0067	glutamate synthase
PB20LOC_021945	COG0069	glutamate synthase activity
PB20LOC_021945	COG0070	glutamate synthase
PB20LOC_021950	COG1242	4 iron, 4 sulfur cluster binding
PB20LOC_021955	COG5002	protein histidine kinase activity
PB20LOC_021955	COG0784	Response regulator, receiver
PB20LOC_021955	COG2198	Histidine kinase
PB20LOC_021960	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PB20LOC_021965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PB20LOC_021975	COG2823	Periplasmic or secreted lipoprotein
PB20LOC_021980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PB20LOC_021985	COG0792	nuclease activity
PB20LOC_021990	COG3107	peptidoglycan biosynthetic process
PB20LOC_021995	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PB20LOC_022015	COG3384	dioxygenase
PB20LOC_022020	COG0754	glutathionylspermidine amidase activity
PB20LOC_022025	COG5463	Belongs to the UPF0441 family
PB20LOC_022035	COG0494	nUDIX hydrolase
PB20LOC_022040	COG3151	Protein conserved in bacteria
PB20LOC_022045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PB20LOC_022050	COG3150	esterase
PB20LOC_022060	COG0583	DNA-binding transcription factor activity
PB20LOC_022065	COG2249	NAD(P)H dehydrogenase (quinone) activity
PB20LOC_022080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PB20LOC_022080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PB20LOC_022085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PB20LOC_022090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PB20LOC_022090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PB20LOC_022090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB20LOC_022095	COG3711	transcriptional antiterminator
PB20LOC_022095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PB20LOC_022110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PB20LOC_022115	COG0204	Acyl-transferase
PB20LOC_022120	COG2132	Multicopper oxidase
PB20LOC_022130	COG0656	L-ascorbic acid biosynthetic process
PB20LOC_022140	COG3501	Rhs element vgr protein