LOCUS MH617220 11817 bp DNA circular ENV 05-AUG-2018 DEFINITION Phage sp. isolate ctdb404, complete genome. ACCESSION MH617220 VERSION MH617220.1 DBLINK BioProject: PRJNA393166 BioSample: SAMN09074552 Sequence Read Archive: SRR7122375 KEYWORDS ENV. SOURCE Phage sp. (animal metagenome) ORGANISM Phage sp. Viruses; unclassified bacterial viruses. REFERENCE 1 (bases 1 to 11817) AUTHORS Tisza,M., Buck,C., Pastrana,D., Welch,N. and Peretti,A. TITLE Uncovering a Universe of Circular DNA Viruses in Animal Metagenomes JOURNAL Unpublished REFERENCE 2 (bases 1 to 11817) AUTHORS Tisza,M., Buck,C., Pastrana,D., Welch,N. and Peretti,A. TITLE Direct Submission JOURNAL Submitted (12-JUL-2018) Lab of Cellular Oncology, National Cancer Institute, 37 Convent Dr., Room 4118, Bethesda, MD 20814, United States of America COMMENT ##Genome-Assembly-Data-START## Assembly Method :: SPAdes v. 3.11.0 Genome Coverage :: 22.269104x Sequencing Technology :: Illumina ##Genome-Assembly-Data-END## FEATURES Location/Qualifiers source 1..11817 /organism="Phage sp." /mol_type="genomic DNA" /isolate="ctdb404" /isolation_source="minnow tissue" /db_xref="taxon:2202648" /environmental_sample /country="USA" /collection_date="01-Jun-2017" /note="genome binned from sequencing reads available in SRX4043871; metagenomic; derived from metagenome: animal metagenome" CDS 1..267 /inference="similar to AA sequence:UniProtKB:S2DMA7_9BACT" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="AXH75728.1" /translation="MKQLVFSKDSKDSFEVRIYNEGDEHNWIRYGKLILNDKGNWELW TGKDYSSEGSGLENDIDDCVEYSYDLDETYDDMSLELADFLEIF" CDS 591..1091 /inference="protein motif:CDD:224186" /note="Phosphatidylglycerophosphatase A and related proteins" /codon_start=1 /transl_table=11 /product="phosphatidylglycerophosphatase A" /protein_id="AXH75735.1" /translation="MSNKPTYHYRDGEAYVFTVKKLKQRGIDLEDICKKAIEEQKKHG VESSMAEVRKYLINLLHKREIMNVIMTGIYLDEQAEKGLIEGPLQDIVASDAPSFGLD ENLAFVITSLFGSIAGTNFGALDVNKTGKAKELDNSEGHVNTFLDDIFSALVASLEAK MAHEDF" CDS 1091..1843 /inference="protein motif:CDD:222885" /note="deoxynucleoside monophosphate kinase; Provisional" /codon_start=1 /transl_table=11 /product="deoxynucleoside monophosphate kinase" /protein_id="AXH75736.1" /translation="MVNVIILSGKMHSGKDTFADKLKLMLEKQSDSVYKISYADSTKS DMVKIIKLILHGRSVEGVMKVMDIGSTYGYQMTKIFNYINQDLADNADLKSEFYSLNN EELQLKLKQFRHYRLIMQIYGTEIRRSLDSKYWINKVLDKIHRIFDDNIGKNVDVIVP DGRFKNEIKLGEDLDSSKYKVLTVRLEAPTAVIKSRIKNDPNDQEEISKETFSHSSET ELDEFKNFDFFVDTTNQNMMKSTMKKLLDLTR" CDS 1855..2574 /inference="protein motif:CDD:224345" /codon_start=1 /transl_table=11 /product="deoxynucleoside kinase" /protein_id="AXH75737.1" /translation="MIINVVAPFGTGKSSLVSLLSQDINAKPYFETVNDSIILPKYYA GGEASRKQLSFALQVEFLNKRFKMLKSANKQELAILDSDLIADSICYKVIHDRGETSE VEYKLYLDLLQNMLMSAIDGSNGYYPALFVYLDIDKKKEVENIVNRGRKMELKDDLAD YYYSINQGFKDWYKGYSQSPVLKIDCTDLDFVNDVNDQNYVLNTIEQKLVDLGLKSKD WLDKVKAKRVFYTVDFLKENL" CDS 2725..3099 /inference="similar to AA sequence:UniProtKB:E9RJE0_BACNA" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="AXH75729.1" /translation="MTEKDYKNSLVKLIQRCYHYKVPGICYGQIKQYHDKLGMSFEGM YRTVLYVLEVKGLTFEKQYGIGYVKYFYQEGKNYTRRSHNTPQVKLTRRQVTIKKQKH RPVLKKIDLNEIELKKENAEHD" CDS 3083..3712 /inference="protein motif:CDD:315955" /codon_start=1 /transl_table=11 /product="HNH endonuclease" /protein_id="AXH75738.1" /translation="MQNMTNTKQKEVWKTYPEYPFIEANQFGEIRTKDRFVEYKNGSK RLIKGRVLKQYLNKSGYMFVHFGLNGKLVNLSVHRVVAICFIPNPDKKPEVNHIDNDR TNNVVSNLEWCSRQYNLDYKKKFGTFGRPVIAVNLDTSEISWFETRSEAARQLDANQS KICKVIKGKVNKTKGYWFCDADLTAVEKTRKKFDNEIACKVKELMSEHL" CDS complement(3442..3732) /note="No HHBLITS hits" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="AXH75733.1" /translation="MFFCCVGHRCSLINSLTLHAISLSNFFLVFSTAVKSASQNQYPL VLFTFPFITLQIFDWLASSCRAASLRVSNQEISEVSKLTAITGRPKVPNFFL" CDS 4090..5004 /inference="similar to AA sequence:UniProtKB:Q97JU2_CLOAB" /note="Phage related protein, YorF B.subtilis homolog" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="AXH75730.1" /translation="MTNIKQFNNNSIQVVGWVKSKDISYATAKDGGQVIRGSVTMEVP VTQQDGSVQLNNVRLNVYQSQFFKSGKANPFYEGFETVIREYVAKDEDAENATYARAN GDISWNVYTNNSGQVVENNRLSARSFSRVDPNVVKPKAVGTLDVYVNDYKEHMEHGEP TNTYDVNGFYVGYNGRVNKLVDFIAPAIMYEKGLQGTWTIGYHINNYAVVDKKQDEAA DGFGTVEEIRSNSYVNNMQITGAQSNKIQVDEEQAQEAINEIRQEVAREQNTQIVETV SGFGNNPFGGAAKPSAANPTINNDDLPF" CDS 5149..6237 /inference="protein motif:CDD:316040" /codon_start=1 /transl_table=11 /product="AAA domain protein" /protein_id="AXH75739.1" /translation="MFTKDQLLNLKPTNVSRVPESYNILLYGESKIGKTTFVNDLFGE RVLNVMTEKRLGGVEGAKGVYVANYADVKSLLRILKDKELQETYDIVSFDTIDNLYLY VDKYVADQYNEVSVGTGGADNLFGRDWRQRDAVWVNLLKEIESLPYTTVFVSHETAAT KEIKMSVVNQSRELLDELTEIGGNVTKKNGQQVMSYTYYQPDVDAKHALPPILKMVDN ILFVDKEIDEEGNEKRVIRLRGSRQYAAGTTLKGMPDTIDFTADAYREAITNAVENNY SKVNKKKTLHSDSDQKEISFKELKSEVESLGKTFSENNDLETLGEISKQVLPDGTKIL ALEENRKEDLLIARDLLLAEAKNKGYIE" CDS 6322..7050 /inference="protein motif:CDD:312982" /note="Phage regulatory protein Rha (Phage_pRha)" /codon_start=1 /transl_table=11 /product="regulatory protein" /protein_id="AXH75740.1" /translation="MEELVIMKENKAVTTSLKVAEIFGKNHRDVMRTIRGLRKNAHTK QMFVESTFVNPQNHQEYQMYYMNRDGFTLLVMGFNGDKALEFKIKYIEAFNKMEEFIK KQPQFAVPQTFGEALQLAADQQMLIEKQKPKVEYYDEQMRNPGLMTVTEIAKDFGLSA AKLNQFLAKKHIQYKQGKHWVLYQEYADQGFAQYEVFAYAEHTIHGEKQKVHNNLKWT QKGRKFIYDLLSEEGIHPTIMIEN" CDS 7065..8315 /inference="similar to AA sequence:INSD:AIS73924.1" /codon_start=1 /transl_table=11 /product="DNA polymerase" /protein_id="AXH75734.1" /translation="MPKYRDDNNKEHEISEEDLSRAVLYKIESQKDQGKANWQRICKM LKADGVDAVKSEGLRQAVKKYQKKIGKLPRRDDFEQSSLTLKLGELSQVKKEIQNERR EFNKLKRELLDESIYRNELEKAVREALRDFKDNRYDYPQDVLNGSERLRITQNEDKPA LVVSVSDWHIGCKFKTSYNEFSYKIVTDLVAEYLSKIERLIDVYGVENVLLLNLGDTI EHTYMRNFSQTFEAEFDFSTQQAKAIELVSRFIKRLCLEHPQTRFYYSAVAGNHDRMN SNKKEVIYGDSFQTILNLFLKNLPLDNFEVIEQESPVKGSISFAGVNIAFEHGDKLNL NNRNIMAAVSQRDRKIYDALLVGHLHHYEAIENNGLFVMSGSLKGADTYSESLNLRAD RSQACLLIRNGTITPLMIRLGDNF" CDS 9033..9356 /inference="similar to AA sequence:UniProtKB:A0A0A7DN04_9CAUD" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="AXH75731.1" /translation="MLEERFDKNFTLMFDSQRGVTPVATIDGRKILINSVDLQWYSDD DRYRGYKNYVKISFYYEDDLKKLSSGDGTLLDDDEAPRKNDITIRQCLYDADSGEWTF PRNEI" CDS 9444..9920 /inference="protein motif:CDD:309932" /codon_start=1 /transl_table=11 /product="nucleoside 2-deoxyribosyltransferase" /protein_id="AXH75741.1" /translation="MTKTKTCYFCAGWFNDEQNKAYKEAMEALKKNKTIDMEHSYVPL EHQYLGIRIDEHPEYLRNREWAQATARGDMIGIQNSDICLAVYLPHQEDPGMGVELGV SYRLGKYNLLVIPDEQWGEPINLMAWYAADNAIKMSELKDFDFNNLEFGFYDGEVY" CDS 9932..10189 /inference="similar to AA sequence:UniProtKB:A0A0A7DMM2_9CAUD" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="AXH75732.1" /translation="MKSRKFVRRFNKLQERTCSNLVAEIQTEDLVYIYRIRNGEKDLF AYNTYYGYWAFAPGEDRVLVTPKTLKLMAKFTKKTYKNARK" CDS 10598..11695 /inference="protein motif:CDD:107349" /note="PBP1_BmpA_PnrA_like" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="AXH75742.1" /translation="MKNVKKKIAIVVTAGVSALMLGACGHRGNNTNNAKKDKVSVALI TGGYGVDDNSFGQMAWSGLKKHGKEYNLSKGAGGYNYFQATGASDYETEMEQAANAKY HTIIAAGFQFAEAIEKTAKKYPKNKFVLIDSQAKGKNVASVMFKSQEASFLAGVAAAK TSKTGKLGWIGAVKSGILSEFEAGFVQGAKWEAKKIHKKISVDREYIGSFTDTSKEKT VAQAMYSKGIDVISQASGGASQGLFVEANNINAQKTSAELKKSKVWAMGVDSDQHALG NFKTKDGKKDNSVLTSIMTRVDTVAYMLSKRSAEGKFPGGQYLKYGLKENAVSLNRDQ IDSSTWKDVLSAKKQILDGKIQVAANMSEVK" ORIGIN 1 atgaagcaat tagtgtttag caaagatagc aaagattcct tcgaggttag aatctacaac 61 gaaggagatg aacacaactg gattcgttat gggaaactca ttctcaatga taagggtaat 121 tgggagcttt ggactgggaa ggattacagc tcagaaggtt ctggcctaga aaatgatatt 181 gacgattgtg tggaatactc atacgatctg gacgagacat acgatgatat gtcgcttgaa 241 ctcgcagatt ttttagaaat tttctaaatt agggttgcaa ctgcagaaaa agcatgttat 301 aatatacttg ttagtaagat aaacacagaa aggacattta tttatgttta aggaattcgt 361 tgatgaacat aacgttaagg caatcagaaa ggccaaccaa ttcgttaaag ccgaaaaggt 421 tgaagttaag aattttgtag cttttgcaga taacttggct aagactcact tgatcgtcga 481 atttgaagaa ccaaaggaag aagctccaac cgctaagaag acgactacta ataagtcaac 541 tgccaagtca actgccaagt caactactac taagtaatag aggaggaaca atgagcaaca 601 agccaactta ccattacaga gacggtgaag cttacgtctt cactgttaaa aagcttaagc 661 aacgtggaat tgatctagaa gacatttgta aaaaggctat tgaagaacag aagaaacacg 721 gtgtggagag tagcatggcc gaggtcagaa aatacttgat caatttgctt cacaaacgtg 781 aaattatgaa cgtgatcatg actggtattt atcttgacga acaggccgaa aagggcttga 841 tcgaagggcc tttgcaagat attgtcgctt cagatgcgcc gtcattcggc ttggatgaaa 901 accttgcttt cgttattacc tcattgtttg gttcaattgc tggcaccaac tttggtgcac 961 ttgacgtaaa caagacaggt aaggctaaag aattagataa ttctgaagga catgtaaaca 1021 ctttcttaga cgacatcttt agcgctttag ttgcttcgtt ggaagctaag atggcacacg 1081 aggacttctg atggttaatg taattatctt gtctggtaag atgcactctg gaaaagatac 1141 ttttgccgac aaattgaagt taatgctgga aaagcaaagc gactctgttt acaagatttc 1201 ttatgcagat tccaccaaga gtgatatggt taaaattatc aaattgattt tgcacggcag 1261 aagtgttgaa ggggttatga aggttatgga tatcgggtct acttacggtt accagatgac 1321 aaaaatcttc aactatatca atcaagattt ggctgataat gctgatttaa aatctgaatt 1381 ttattcgtta aataatgagg aactgcagct taagttgaag cagtttaggc actataggtt 1441 aataatgcaa atctacggta ctgaaattag acgtagtttg gacagtaaat attggataaa 1501 taaggtttta gacaagattc atcgaatttt tgatgacaat atcggcaaga acgttgatgt 1561 gatagtacca gacgggcggt ttaaaaacga aattaaactg ggcgaagatt tagattcttc 1621 gaaatacaaa gttttgaccg tacgtttgga agctcctact gcagtaatca agagtcgaat 1681 taagaatgac ccaaacgacc aggaagagat ttcaaaagaa acttttagtc attcatcaga 1741 aacagaatta gatgagttta aaaattttga tttctttgtt gacacaacca atcaaaatat 1801 gatgaaatca acgatgaaga aacttttaga tttaacgagg tagaaaggta aaacatgatt 1861 atcaacgtag ttgcgccatt tggcactggt aagagttctc ttgttagttt actgtctcaa 1921 gatattaacg ccaaacctta ctttgaaaca gttaacgaca gtattatctt acctaagtat 1981 tatgctggtg gtgaagcaag tcgtaagcaa ttatcattcg ctttacaagt ggaatttcta 2041 aacaagcgct ttaagatgct gaagtcagct aataagcagg aactggctat cttagatagc 2101 gacttgatcg cagactcaat ttgctataag gtaattcacg atcgtggtga aacaagtgaa 2161 gttgaataca agttgtattt agatttactt cagaatatgt taatgagtgc gatcgatggc 2221 agcaacggtt attatccagc tctgttcgtt tacttagaca ttgacaagaa gaaggaagta 2281 gaaaacatcg tcaatcgtgg ccgtaagatg gaacttaagg atgatctggc tgattactac 2341 tactccatta accaaggctt taaggattgg tacaagggct acagtcaatc tccagttctt 2401 aaaattgatt gcactgactt agatttcgtc aatgatgtaa atgaccaaaa ctacgtcttg 2461 aacaccattg aacaaaagtt ggttgatctg ggtttgaagt ccaaggattg gctggacaag 2521 gttaaggcaa agcgggtgtt ttatactgtg gattttttaa aggaaaatct ttagaaaaga 2581 aggaaaggta aactaaaatg caaatgaaga agaagacgtt ctaacaaagt aaaaaataaa 2641 gacaaaaaag caagttggtt ttaaaatcga cttgcttttt gtctttatct gtgttataat 2701 agactcataa agaaaggaga acatatgaca gagaaggact ataaaaacag tctcgtaaag 2761 ctaattcaga ggtgttatca ctataaagtt cctggaattt gctacggtca aattaaacag 2821 tatcatgaca agctgggaat gagttttgaa ggcatgtacc gaaccgtttt gtacgtgctt 2881 gaagtgaaag gtttgacgtt cgagaagcag tatggaatcg gttatgttaa gtacttctat 2941 caagaaggta aaaactacac cagaagatcg cacaacaccc ctcaagtcaa gttaaccaga 3001 agacaggtaa caattaagaa acaaaaacat agaccagtct tgaaaaaaat tgatttaaat 3061 gaaattgaac taaagaaaga gaatgcagaa catgactaat acaaaacaaa aagaagtttg 3121 gaaaacatat ccagaatatc cgttcattga agcaaatcaa tttggtgaaa tcagaacgaa 3181 agacagattt gtggagtata aaaatggcag caaacgattg attaagggac gtgttttaaa 3241 acaatacctg aacaaaagcg gctacatgtt tgtacatttc ggcttgaacg gtaagctagt 3301 caacctgtcc gtccaccgcg tggtggcaat ctgctttatt cctaatcctg acaaaaaacc 3361 agaagtaaat cacattgata atgatagaac taataatgtt gtaagcaatt tagaatggtg 3421 ttcgagacag tataatctag attacaaaaa gaaatttgga acttttggac gaccggtgat 3481 tgcagttaat ttagatactt ctgaaatttc ctggtttgaa acgcgaagtg aagctgcgcg 3541 acaacttgat gctaaccaat caaaaatttg taaggttata aaaggaaaag tgaacaaaac 3601 caaagggtat tggttctgcg atgcagattt aactgctgtt gaaaagacaa gaaaaaagtt 3661 tgataatgag attgcatgta aagttaaaga attaatgagt gagcacctat gaccaacgca 3721 acaaaaaaac atctaacgtc tcaaaaacta ttgtttataa aaggagtgta gtctactatg 3781 aatccgtcag acaagctgta agttttctct tactaaaacc gagcattagc tcaacggtag 3841 agcgaccaac ttataattgg tttatagaag ttcgactctt ctatgttcga tagctaggat 3901 taaattagct taggttttat attctttttt ctttgtctgt catagttaaa aaagttcttc 3961 taaattgagt ggtgtaagat ggttctaaac taagggtccg attcccttat acactatagg 4021 ctcatcaagc ctaaaaaata gttcaatagt tcaatagttt ggtttaattt tagtgaggta 4081 aaaaaagcta tgacaaacat caagcaattc aacaacaatt ctatccaggt tgttggctgg 4141 gtaaagagca aggatatcag ctacgcaacc gcaaaggacg gtggccaggt tatccgtggt 4201 agtgttacga tggaagttcc agtaactcaa caagacggct ctgtacagct caacaacgtc 4261 agattaaacg tatatcaaag tcaatttttc aagtcgggta aggcaaatcc attctacgaa 4321 gggttcgaaa ctgttattag agaatacgtt gctaaggatg aagatgctga aaacgctact 4381 tacgcaagag caaatggtga tatttcttgg aacgtttaca ctaataacag cgggcaagta 4441 gttgaaaata accgcttgtc agctagaagc ttctctagag ttgaccctaa cgttgttaag 4501 cctaaggcag taggcacttt ggacgtttac gtaaatgact acaaggaaca catggagcac 4561 ggtgaaccta ctaacactta cgatgttaat ggtttctacg ttggttacaa tggcagagtt 4621 aataaattgg ttgactttat tgctccagct atcatgtacg aaaagggttt acaaggtact 4681 tggactatcg gctatcatat taacaactat gcggtagtcg ataaaaagca agatgaggcg 4741 gcagacggat ttggtacagt cgaagaaatt agatctaatt cttatgtaaa caacatgcaa 4801 atcactggtg cacagtcaaa caagattcaa gtcgatgaag aacaagctca agaagctatc 4861 aacgaaattc ggcaagaagt tgctagagaa cagaatacgc aaattgttga aaccgtctct 4921 ggctttggta acaatccgtt cggtggtgct gctaaaccaa gtgcagcaaa tccgactatt 4981 aataatgatg atcttccttt ctaggaattt taaaaagcta catgttaaaa tcacgtggct 5041 ttttttattt ttttagaaaa aagtaccttt aaggttgtaa ctgcaaaaat tatgtgatac 5101 aatgttaatt gtatcaaagt tacaaaagtt ttttttagag aggtaagtat gtttacaaaa 5161 gatcaattac ttaatttaaa accaaccaat gtttcaagag tacctgaaag ctacaacatt 5221 ttgctttacg gagaatccaa gattggtaag actacgttcg tgaacgattt gtttggtgaa 5281 cgtgtgctaa acgttatgac ggaaaaacgt cttgggggcg tggaaggtgc taaaggcgtt 5341 tacgtagcaa actatgcaga tgtcaaaagt ttacttagaa ttttgaagga taaggaatta 5401 caagaaactt atgatatcgt gtcatttgat acgattgaca atctatactt atatgtcgat 5461 aaatatgttg ctgaccaata caacgaggtg tctgttggta ctggcggagc agacaacttg 5521 ttcggtcgtg actggcgtca aagagatgct gtatgggtca atcttttgaa ggaaattgaa 5581 tctttgcctt atacgaccgt ttttgtttca catgaaacag cggcaactaa ggaaattaag 5641 atgagcgtag taaaccagag cagagaactt cttgacgaac tcactgaaat tggtggcaac 5701 gttaccaaga agaacggaca gcaggtgatg agttatactt actaccaacc agacgttgat 5761 gccaagcatg ctttgccacc tattttgaaa atggtcgaca atattttatt cgttgataaa 5821 gaaattgacg aagaaggaaa cgaaaagcgt gtaattcgct tgcgtggtag tagacaatac 5881 gcagctggta caaccttgaa agggatgcca gatacgattg actttacggc agatgcttac 5941 agagaagcga ttaccaacgc tgttgaaaat aactactcta aggttaataa gaagaagacc 6001 ttgcactctg attctgacca aaaagaaatc agcttcaagg aactgaagag tgaagttgaa 6061 tcacttggta agactttttc ggaaaacaat gatttggaaa cccttggtga aatttcaaag 6121 caagtgcttc ctgacggaac aaagatttta gctttggaag aaaatcgtaa ggaagacctt 6181 ctgattgcta gagacttgct tttagctgaa gctaagaaca aagggtatat tgaataaaat 6241 agtttttttg aggagtgtca gattggcact cctttagcta aatacaaatt agatttgaga 6301 aatatcacga aaggaactgc catggaagaa ttagtaatca tgaaagaaaa caaagctgtt 6361 actaccagct tgaaagtggc agaaatcttt ggtaaaaatc atcgcgacgt tatgcggacg 6421 atcaggggtc tgcgcaaaaa tgcgcatacc aaacaaatgt tcgtcgaatc aacatttgtg 6481 aacccgcaaa accaccaaga gtaccaaatg tactacatga acagagacgg atttaccctt 6541 ctagtcatgg gtttcaacgg tgataaggca ctcgagttca agattaagta tattgaagct 6601 ttcaacaaga tggaggagtt catcaaaaag caaccacagt ttgcagttcc acaaactttt 6661 ggcgaagcac ttcagttggc tgctgaccag caaatgctaa ttgaaaagca aaagccaaaa 6721 gttgaatact acgatgagca gatgcggaat cctggtctta tgaccgttac agaaattgcg 6781 aaagattttg gcttgtcagc cgctaaactc aatcagtttc tagcaaaaaa acatatccaa 6841 tacaaacaag gcaagcactg ggttttgtat caagaatatg ccgatcaagg atttgcccaa 6901 tatgaagtgt ttgcctatgc agaacatacg attcacggtg aaaaacaaaa agttcacaac 6961 aatctaaagt ggactcagaa aggacgcaaa ttcatctatg acctgctgag cgaagaaggt 7021 atccatccga caatcatgat tgaaaattaa aaggagtata gtttatgcca aagtacagag 7081 acgacaataa taaagagcac gagattagcg aagaagattt gtcacgtgct gtcttatata 7141 agatagagtc tcagaaagac caaggaaaag cgaattggca aagaatttgt aaaatgctaa 7201 aagctgatgg tgtcgatgct gtaaaaagtg aaggcctcag acaagctgtt aaaaaatacc 7261 aaaagaagat tggtaaactg cctcgtagag atgattttga gcagagttct ctaacgttaa 7321 aacttggtga attgtctcaa gtaaaaaaag agatacaaaa cgaaagaaga gaatttaaca 7381 agctcaaacg tgagcttttg gacgaaagca tctatcgtaa tgagcttgag aaagctgtga 7441 gagaggctct gagagacttt aaggataaca ggtatgatta tccacaagat gtcttaaatg 7501 gttcagaaag gcttagaatt actcagaatg aagataaacc agctttagtt gtttctgttt 7561 ctgactggca tatcggctgc aagtttaaga cgagttataa tgagtttagc tacaagattg 7621 ttactgattt ggtagctgaa tatttaagca agattgaaag actcatcgat gtttacggtg 7681 ttgaaaatgt gttgctttta aaccttggag acacgattga acatacgtac atgaggaatt 7741 tttcacaaac atttgaagcg gagtttgatt tctcaaccca acaggctaaa gctattgaat 7801 tagtgtctag atttattaaa agactatgtt tggaacatcc tcaaaccagg ttctattata 7861 gtgctgtggc ggggaatcac gacagaatga acagcaataa gaaagaggta atttacggtg 7921 acagcttcca gactatcttg aatctgtttc tgaagaactt acctttagat aatttcgaag 7981 tgattgaaca agaatctcca gttaagggta gtattagttt tgctggggtt aacattgcct 8041 ttgagcatgg tgacaagctt aatctaaaca acagaaacat catggctgca gtttcacagc 8101 gtgacagaaa gatttatgac gctctgctgg tgggacattt acaccattac gaggcgattg 8161 aaaacaatgg actgtttgta atgtctggtt cgttgaaagg cgccgatact tattcggaga 8221 gcttgaattt gcgtgcagat agaagtcaag cttgtttact gattaggaat ggtacgatta 8281 cgcctctcat gattcgactt ggtgacaatt tttaaaaaat tttttctaaa aagtcttgca 8341 ttttagattc agagtgctac aatagttagt gtcaagaaag acgaaaactg ttattaaaaa 8401 ggaggacacg acagtgaaag atcgcagtct atatggattc cacttgatgg aattaaaaga 8461 cgattatgtt gcttttaaat ctggcaagga cggaaaagaa gaaattaaat tttcggttaa 8521 caagaaattt ttaaaagaat gcgacaaacc attaaatatg gtcagacgat tagaattaat 8581 ttttaagatg ttcctaaagg aagcatatgg agaagagtga tggaagaagc atacttgatt 8641 aaaacgaaaa atatcaaacc cctttggcaa agattgggtt tcggttcaga aaagatcatg 8701 ttgcaaaatc agaaaagata tgttaaacta gattagtagt taagagcact acgaagtaga 8761 tattctagga gggcactttg ggacataaag tagattttga taagtatcaa gtagtagttc 8821 tagttaacaa taaagaaata attgttaaaa atttcagctt tgttgttgat atggaaagta 8881 atataccatt tatggtgtgc actggcattt taaataatag ttggactgac ctggctatta 8941 acaatgctaa catcatctat gttagagatc tatttgagag tgagaagcgt attgttggac 9001 aaatcgaaga ttcatcgaag taaaggagta ttatgttaga agagagattt gataagaact 9061 tcactttaat gtttgattct caaaggggtg tcacacctgt tgctactatt gatggaagaa 9121 agatcttaat taattctgtg gacttgcaat ggtactccga tgacgatcgt tatagaggtt 9181 ataaaaatta cgttaagatt agtttttact atgaagacga tcttaaaaaa ttgtcaagcg 9241 gtgatggaac tctcttagat gatgatgaag cacctagaaa aaatgatatt acgattagac 9301 aatgcctgta tgatgcggat tctggcgagt ggacttttcc gaggaacgag atttgattaa 9361 tcagaaaaga ttagaattta tgcttgatat ttcgtaatta atgtataaga atgtagtttg 9421 attattaaga aggagagaat tacatgacta agactaagac ttgctacttt tgtgcgggat 9481 ggttcaacga tgaacagaac aaggcttaca aggaagctat ggaagctttg aagaaaaaca 9541 agacgatcga tatggaacac tcgtacgttc cactggaaca tcaatattta ggaattagaa 9601 tcgatgaaca tcccgaatac ttgagaaata gagagtgggc acaagctacc gctagaggtg 9661 atatgatcgg catccagaac tcagatattt gtttggctgt ttatctaccc caccaggaag 9721 accctggtat gggggtggaa cttggcgtat cttatagatt gggcaagtat aatctgttag 9781 tcattccaga cgaacaatgg ggcgaaccta tcaacttaat ggcttggtat gcggcagata 9841 atgcaatcaa gatgtcggag ttaaaggact ttgattttaa caatttagag tttggttttt 9901 atgacggaga agtctattga tataccttaa tatgaaatca cgtaagtttg ttcgcaggtt 9961 caacaagcta caagaaagaa cttgttcaaa tctagtcgca gaaattcaga cagaagatct 10021 ggtatatata tatcgaatta gaaatggaga aaaagacctg tttgcatata atacttacta 10081 tggttattgg gcatttgccc ctggagaaga cagagtacta gtaacgccaa agactctaaa 10141 gttaatggca aagttcacta agaagaccta taaaaatgct agaaagtgag cagcaaaatg 10201 gataatgtga gacgttgctc ctggtgcaga actcctatag aaaaaggata tggctacatc 10261 gcaatcaata atggagaaga attttgctcc tacgattgct ttaatgatta ttgctgggat 10321 tatttcgagg cggaggaaaa agaataatga cagtttttgt tttgtatacc gtagtagaat 10381 caaacgttga aattaagggt gtcttttcaa ctaaagaaaa agctgaagca gagcgtaagc 10441 aaatcagaga acgcttggta gagcttggtg ttagacattt cgtatcagtg ttaattgatg 10501 agtgtgaaat gggtttttaa ggttgcaact gataactttt aagtggtata atatctaagt 10561 aataaataat tagaaagaac gagaagggac aaatctaatg aagaacgtta agaagaagat 10621 tgctattgtc gttactgctg gtgttagtgc tttgatgctt ggtgcttgtg ggcacagagg 10681 gaacaacaca aacaacgcta agaaggacaa ggtgtccgtt gcgttgatta ccggtgggta 10741 tggtgtcgac gacaactcgt tcggtcaaat ggcttggtct ggactgaaga agcacggtaa 10801 ggaatacaat ctctcaaaag gtgctggcgg ttataactac ttccaagcca ctggtgctag 10861 tgactatgaa accgaaatgg aacaagcggc taacgctaaa tatcacacaa ttatcgcagc 10921 aggtttccaa tttgcagaag ctatcgaaaa gacagctaag aagtatccaa agaataagtt 10981 tgttcttatt gacagtcaag caaaaggtaa gaacgttgca agcgtaatgt ttaagtctca 11041 agaagcttca ttcctagctg gtgtagccgc tgctaagact tctaagactg gtaagcttgg 11101 ctggattggt gctgtaaaga gcggaatctt gtccgaattt gaagctggtt ttgtgcaagg 11161 tgctaagtgg gaagctaaga agattcataa gaagatttca gtcgatagag aatatatcgg 11221 ttcatttacc gacacgtcaa aggaaaaaac agtagcacaa gcgatgtaca gcaagggtat 11281 tgatgtgatc tctcaagcat ctggcggggc atcacaaggt ttgttcgttg aagcaaacaa 11341 catcaatgca caaaagacca gcgctgaact caagaagtcg aaggtatggg ctatgggtgt 11401 tgatagtgac caacacgcac tgggcaactt taagactaag gacggtaaga aggataactc 11461 cgtcttgact tcgatcatga cgagagtcga cacggttgct tacatgttga gtaagcgatc 11521 agccgaaggc aagtttcctg gtggtcaata tctcaagtac ggtttgaaag aaaatgctgt 11581 ttcacttaac agagaccaaa tcgatagctc cacgtggaaa gatgttttga gcgctaagaa 11641 gcagatcctc gatggtaaaa ttcaagtggc tgcaaacatg tcagaagtta agtaatttaa 11701 ttttaaaagg acgctaaaaa gcgccctttt ttgtattttg gggttgattt ttgttgtgtg 11761 tgtgttatca tatagttgtc aaaggaaata atataaaaca cagaaaggac aatataa //