locus-tag	class	description
PSMK_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PSMK_00030	COG1136	(ABC) transporter
PSMK_00110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSMK_00130	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PSMK_00250	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSMK_00250	COG0022	dehydrogenase e1 component
PSMK_00290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PSMK_00300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PSMK_00320	COG0848	biopolymer transport protein
PSMK_00340	COG0811	peptide transport
PSMK_00380	COG0741	lytic transglycosylase activity
PSMK_00390	COG0552	protein localization to endoplasmic reticulum
PSMK_00400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PSMK_00410	COG0724	RNA recognition motif
PSMK_00420	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSMK_00420	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSMK_00500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSMK_00550	COG1970	mechanosensitive ion channel activity
PSMK_00640	COG2244	polysaccharide biosynthetic process
PSMK_00700	COG0110	maltose O-acetyltransferase activity
PSMK_00720	COG0438	transferase activity, transferring glycosyl groups
PSMK_00740	COG0463	Glycosyl transferase, family 2
PSMK_00820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PSMK_00870	COG0529	Catalyzes the synthesis of activated sulfate
PSMK_00910	COG0217	transcriptional regulatory protein
PSMK_00940	COG0482	sulfurtransferase activity
PSMK_00950	COG4251	negative regulation of phosphorylation
PSMK_00960	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PSMK_00990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PSMK_01000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PSMK_01010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PSMK_01020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PSMK_01050	COG0357	Ribosomal RNA small subunit methyltransferase G
PSMK_01070	COG0628	permease
PSMK_01160	COG0673	inositol 2-dehydrogenase activity
PSMK_01210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PSMK_01240	COG0714	Associated with various cellular activities
PSMK_01260	COG1381	Involved in DNA repair and RecF pathway recombination
PSMK_01330	COG0545	Peptidyl-prolyl cis-trans isomerase
PSMK_01340	COG2197	response regulator
PSMK_01350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PSMK_01380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PSMK_01400	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PSMK_01420	COG2755	lipolytic protein G-D-S-L family
PSMK_01420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PSMK_01430	COG2208	phosphoserine phosphatase activity
PSMK_01430	COG2770	Histidine kinase
PSMK_01460	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PSMK_01470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PSMK_01500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PSMK_01590	COG1706	bacterial-type flagellum-dependent cell motility
PSMK_01600	COG2957	Belongs to the agmatine deiminase family
PSMK_01610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PSMK_01700	COG2255	four-way junction helicase activity
PSMK_01720	COG5001	Diguanylate cyclase
PSMK_01780	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSMK_01810	COG0259	pyridoxamine-phosphate oxidase activity
PSMK_01920	COG1021	2,3-dihydroxybenzoate-AMP ligase
PSMK_01950	COG0356	it plays a direct role in the translocation of protons across the membrane
PSMK_01960	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PSMK_01970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PSMK_01980	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PSMK_01990	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PSMK_02110	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PSMK_02120	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
PSMK_02210	COG2995	paraquat-inducible protein a
PSMK_02260	COG2205	protein histidine kinase activity
PSMK_02270	COG3706	GGDEF domain
PSMK_02290	COG1475	DNA binding
PSMK_02310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PSMK_02310	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PSMK_02320	COG0577	efflux transmembrane transporter activity
PSMK_02330	COG1090	epimerase
PSMK_02340	COG1132	(ABC) transporter
PSMK_02350	COG1132	(ABC) transporter
PSMK_02390	COG0589	response to stress
PSMK_02430	COG0569	domain protein
PSMK_02430	COG0189	ligase activity
PSMK_02440	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PSMK_02450	COG0402	S-adenosylhomocysteine deaminase activity
PSMK_02480	COG0714	Associated with various cellular activities
PSMK_02530	COG1183	phosphatidylcholine synthase activity
PSMK_02550	COG2226	methyltransferase
PSMK_02610	COG3401	FG-GAP repeat protein
PSMK_02680	COG1215	transferase activity, transferring glycosyl groups
PSMK_02730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PSMK_02760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PSMK_02770	COG1061	Type III restriction enzyme res subunit
PSMK_02800	COG1002	Type II restriction enzyme, methylase subunits
PSMK_02820	COG0799	negative regulation of ribosome biogenesis
PSMK_02840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PSMK_02880	COG0616	signal peptide processing
PSMK_02890	COG0590	tRNA wobble adenosine to inosine editing
PSMK_02910	COG0717	Belongs to the dCTP deaminase family
PSMK_02940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PSMK_02950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PSMK_02970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PSMK_02980	COG0151	Belongs to the GarS family
PSMK_03000	COG0438	transferase activity, transferring glycosyl groups
PSMK_03010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PSMK_03020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSMK_03060	COG0501	Belongs to the peptidase M48B family
PSMK_03070	COG2226	methyltransferase
PSMK_03120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSMK_03170	COG0084	hydrolase, TatD family'
PSMK_03200	COG0719	Fe-S assembly protein
PSMK_03210	COG0396	ATPase activity
PSMK_03220	COG0719	Fe-S assembly protein
PSMK_03230	COG0316	Belongs to the HesB IscA family
PSMK_03290	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PSMK_03350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PSMK_03390	COG0567	Dehydrogenase, E1 component
PSMK_03410	COG1028	Short-chain dehydrogenase reductase Sdr
PSMK_03450	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PSMK_03510	COG1595	DNA-templated transcription, initiation
PSMK_03530	COG0483	inositol monophosphate 1-phosphatase activity
PSMK_03580	COG0702	epimerase
PSMK_03630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PSMK_03690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PSMK_03710	COG0181	hydroxymethylbilane synthase activity
PSMK_03720	COG1301	dicarboxylic acid transport
PSMK_03760	COG1233	COG1233 Phytoene dehydrogenase and related
PSMK_03780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PSMK_03800	COG2066	Belongs to the glutaminase family
PSMK_03840	COG0592	DNA-directed DNA polymerase activity
PSMK_03850	COG1122	ATPase activity
PSMK_03870	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PSMK_03880	COG0542	response to heat
PSMK_03890	COG3706	GGDEF domain
PSMK_03900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PSMK_03930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PSMK_04000	COG1216	Glycosyl transferase, family 2
PSMK_04000	COG0438	transferase activity, transferring glycosyl groups
PSMK_04010	COG1045	serine acetyltransferase
PSMK_04030	COG0673	inositol 2-dehydrogenase activity
PSMK_04050	COG0438	transferase activity, transferring glycosyl groups
PSMK_04050	COG0297	glycogen (starch) synthase activity
PSMK_04070	COG0438	transferase activity, transferring glycosyl groups
PSMK_04080	COG1215	transferase activity, transferring glycosyl groups
PSMK_04090	COG0463	Glycosyl transferase, family 2
PSMK_04130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSMK_04150	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PSMK_04160	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
PSMK_04190	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
PSMK_04220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PSMK_04230	COG0673	inositol 2-dehydrogenase activity
PSMK_04300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PSMK_04310	COG0463	Glycosyl transferase, family 2
PSMK_04320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PSMK_04360	COG1215	transferase activity, transferring glycosyl groups
PSMK_04380	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PSMK_04400	COG2133	pyrroloquinoline quinone binding
PSMK_04430	COG0475	glutathione-regulated potassium exporter activity
PSMK_04500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PSMK_04540	COG0667	Aldo Keto reductase
PSMK_04560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PSMK_04570	COG0012	GTP binding
PSMK_04720	COG0811	peptide transport
PSMK_04770	COG0505	Belongs to the CarA family
PSMK_04810	COG0612	Peptidase, M16
PSMK_04860	COG1917	Cupin 2, conserved barrel domain protein
PSMK_04860	COG4977	sequence-specific DNA binding
PSMK_04880	COG4968	Prepilin-type N-terminal cleavage methylation domain
PSMK_04950	COG3264	Mechanosensitive ion channel
PSMK_04950	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PSMK_04970	COG0612	Peptidase, M16
PSMK_05000	COG0318	PFAM AMP-dependent synthetase and ligase
PSMK_05010	COG0110	maltose O-acetyltransferase activity
PSMK_05020	COG1573	uracil-dna glycosylase
PSMK_05030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PSMK_05030	COG3153	acetyltransferase
PSMK_05040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PSMK_05040	COG3153	acetyltransferase
PSMK_05050	COG0602	queuosine metabolic process
PSMK_05130	COG1561	YicC-like family, N-terminal region
PSMK_05150	COG0149	triose-phosphate isomerase activity
PSMK_05240	COG3328	transposase activity
PSMK_05310	COG4191	Histidine kinase
PSMK_05320	COG1653	transport
PSMK_05330	COG1175	transmembrane transport
PSMK_05340	COG0395	ABC-type sugar transport system, permease component
PSMK_05400	COG2890	protein-(glutamine-N5) methyltransferase activity
PSMK_05420	COG0788	formyltetrahydrofolate deformylase activity
PSMK_05440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PSMK_05460	COG0515	serine threonine protein kinase
PSMK_05510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PSMK_05610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PSMK_05650	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PSMK_05660	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PSMK_05670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PSMK_05730	COG1028	Short-chain dehydrogenase reductase Sdr
PSMK_05780	COG3177	Filamentation induced by cAMP protein fic
PSMK_05790	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PSMK_05800	COG0825	malonyl-CoA metabolic process
PSMK_05810	COG0287	Prephenate dehydrogenase
PSMK_05820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PSMK_05840	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PSMK_05860	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSMK_05870	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PSMK_05870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSMK_05880	COG0174	glutamine synthetase
PSMK_05890	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PSMK_05910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PSMK_05920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSMK_05950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSMK_05980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PSMK_05980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PSMK_06060	COG2308	Evidence 4 Homologs of previously reported genes of
PSMK_06080	COG0383	alpha-mannosidase activity
PSMK_06150	COG1482	cell wall glycoprotein biosynthetic process
PSMK_06200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PSMK_06220	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PSMK_06290	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PSMK_06300	COG0438	transferase activity, transferring glycosyl groups
PSMK_06310	COG1132	(ABC) transporter
PSMK_06380	COG0438	transferase activity, transferring glycosyl groups
PSMK_06460	COG2442	InterPro IPR007367
PSMK_06550	COG1320	monovalent cation:proton antiporter activity
PSMK_06560	COG2212	antiporter activity
PSMK_06710	COG1863	multisubunit Na H antiporter MnhE subunit
PSMK_06740	COG2111	Na H antiporter
PSMK_06820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSMK_06850	COG3875	lactate racemase activity
PSMK_06880	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PSMK_06890	COG1518	maintenance of DNA repeat elements
PSMK_06950	COG5285	phytanoyl-CoA dioxygenase
PSMK_06960	COG3708	Transcriptional regulator
PSMK_06960	COG2207	Transcriptional regulator
PSMK_06990	COG0336	Belongs to the RNA methyltransferase TrmD family
PSMK_07000	COG0228	four-way junction DNA binding
PSMK_07010	COG0438	transferase activity, transferring glycosyl groups
PSMK_07180	COG0066	3-isopropylmalate dehydratase activity
PSMK_07230	COG3119	arylsulfatase activity
PSMK_07270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSMK_07280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSMK_07290	COG0742	ribosomal rna small subunit methyltransferase
PSMK_07330	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PSMK_07350	COG0237	dephospho-CoA kinase activity
PSMK_07360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PSMK_07380	COG0138	bifunctional purine biosynthesis protein purh
PSMK_07400	COG0561	phosphatase activity
PSMK_07410	COG0470	DNA polymerase III
PSMK_07430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PSMK_07440	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PSMK_07510	COG0437	4 iron, 4 sulfur cluster binding
PSMK_07540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PSMK_07550	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
PSMK_07590	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PSMK_07780	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PSMK_07790	COG0758	DNA mediated transformation
PSMK_07850	COG0805	protein transport
PSMK_07860	COG3976	FMN-binding domain protein
PSMK_07860	COG1053	succinate dehydrogenase
PSMK_07860	COG0431	NADPH-dependent FMN reductase
PSMK_07890	COG0004	ammonium transporteR
PSMK_07920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PSMK_07960	COG0772	Belongs to the SEDS family
PSMK_07970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PSMK_08000	COG1074	ATP-dependent DNA helicase activity
PSMK_08030	COG1030	water channel activity
PSMK_08040	COG0525	valine-tRNA ligase activity
PSMK_08050	COG3046	protein related to deoxyribodipyrimidine photolyase
PSMK_08090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSMK_08110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PSMK_08130	COG0772	Belongs to the SEDS family
PSMK_08140	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PSMK_08160	COG1160	GTP binding
PSMK_08180	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PSMK_08290	COG3706	GGDEF domain
PSMK_08310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PSMK_08340	COG0250	Participates in transcription elongation, termination and antitermination
PSMK_08380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PSMK_08440	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PSMK_08450	COG0009	L-threonylcarbamoyladenylate synthase
PSMK_08460	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PSMK_08470	COG0081	regulation of translation
PSMK_08480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PSMK_08490	COG0222	ribosome binding
PSMK_08500	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PSMK_08510	COG0358	DNA primase activity
PSMK_08520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PSMK_08530	COG0484	heat shock protein binding
PSMK_08540	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PSMK_08560	COG0673	inositol 2-dehydrogenase activity
PSMK_08590	COG1028	Short-chain dehydrogenase reductase Sdr
PSMK_08620	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSMK_08700	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PSMK_08840	COG1175	transmembrane transport
PSMK_08910	COG2207	Transcriptional regulator
PSMK_08920	COG1943	Transposase
PSMK_08960	COG0673	inositol 2-dehydrogenase activity
PSMK_08990	COG1028	Short-chain dehydrogenase reductase Sdr
PSMK_09020	COG1012	belongs to the aldehyde dehydrogenase family
PSMK_09200	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PSMK_09270	COG2423	ornithine cyclodeaminase activity
PSMK_09300	COG4948	Mandelate Racemase Muconate Lactonizing
PSMK_09350	COG0251	oxidation-reduction process
PSMK_09360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PSMK_09360	COG0473	3-isopropylmalate dehydrogenase activity
PSMK_09370	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSMK_09390	COG1609	Transcriptional regulator
PSMK_09470	COG3693	PFAM glycoside hydrolase, family 10
PSMK_09520	COG1609	Transcriptional regulator
PSMK_09540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PSMK_09570	COG3481	metal-dependent phosphohydrolase, HD sub domain
PSMK_09590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PSMK_09590	COG0574	Belongs to the PEP-utilizing enzyme family
PSMK_09660	COG1609	Transcriptional regulator
PSMK_09670	COG3119	arylsulfatase activity
PSMK_09690	COG3119	arylsulfatase activity
PSMK_09710	COG1609	Transcriptional regulator
PSMK_09790	COG1609	Transcriptional regulator
PSMK_09820	COG0612	Peptidase, M16
PSMK_09920	COG3250	beta-galactosidase activity
PSMK_09960	COG1609	Transcriptional regulator
PSMK_10080	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PSMK_10100	COG0579	oxidoreductase
PSMK_10170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PSMK_10250	COG0432	Pfam Uncharacterised protein family UPF0047
PSMK_10260	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PSMK_10300	COG4974	Belongs to the 'phage' integrase family
PSMK_10320	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PSMK_10340	COG3394	polysaccharide catabolic process
PSMK_10350	COG0673	inositol 2-dehydrogenase activity
PSMK_10360	COG0673	inositol 2-dehydrogenase activity
PSMK_10410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PSMK_10440	COG0673	inositol 2-dehydrogenase activity
PSMK_10450	COG2081	HI0933 family
PSMK_10520	COG1418	mRNA catabolic process
PSMK_10550	COG2205	protein histidine kinase activity
PSMK_10550	COG2202	Pas domain
PSMK_10580	COG1511	domain protein
PSMK_10580	COG3264	Mechanosensitive ion channel
PSMK_10610	COG3360	Dodecin
PSMK_10630	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PSMK_10640	COG1214	PFAM Peptidase M22, glycoprotease
PSMK_10650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PSMK_10690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PSMK_10710	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PSMK_10720	COG0105	UTP biosynthetic process
PSMK_10770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PSMK_10800	COG1201	RNA secondary structure unwinding
PSMK_10880	COG0084	hydrolase, TatD family'
PSMK_10920	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PSMK_10940	COG3437	response regulator, receiver
PSMK_10960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PSMK_10970	COG1904	glucuronate isomerase
PSMK_11020	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PSMK_11030	COG0285	dihydrofolate synthase activity
PSMK_11040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PSMK_11060	COG0495	leucyl-tRNA aminoacylation
PSMK_11090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PSMK_11100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PSMK_11130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PSMK_11140	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PSMK_11150	COG1758	RNA polymerase activity
PSMK_11190	COG1648	precorrin-2 dehydrogenase activity
PSMK_11190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PSMK_11210	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PSMK_11220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PSMK_11230	COG1692	metallophosphoesterase
PSMK_11240	COG2323	membrane
PSMK_11260	COG0563	adenylate kinase activity
PSMK_11280	COG1322	Protein conserved in bacteria
PSMK_11290	COG3119	arylsulfatase activity
PSMK_11440	COG1028	Short-chain dehydrogenase reductase Sdr
PSMK_11480	COG3119	arylsulfatase activity
PSMK_11540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSMK_11550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSMK_11570	COG3119	arylsulfatase activity
PSMK_11590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PSMK_11600	COG0436	Aminotransferase
PSMK_11630	COG4106	trans-aconitate 2-methyltransferase activity
PSMK_11640	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSMK_11650	COG0716	FMN binding
PSMK_11680	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
PSMK_11710	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PSMK_11720	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PSMK_11760	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PSMK_11770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PSMK_11780	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PSMK_11800	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PSMK_11810	COG4864	UPF0365 protein
PSMK_11830	COG1335	isochorismatase
PSMK_11850	COG0792	nuclease activity
PSMK_11860	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PSMK_11890	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PSMK_11890	COG0321	lipoyl(octanoyl) transferase activity
PSMK_11930	COG3361	conserved protein (COG2071)
PSMK_11940	COG0489	protein tyrosine kinase activity
PSMK_11970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PSMK_11990	COG0077	Prephenate dehydratase
PSMK_11990	COG1605	Chorismate mutase
PSMK_12010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PSMK_12010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PSMK_12040	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PSMK_12110	COG0714	Associated with various cellular activities
PSMK_12130	COG0765	amino acid transport
PSMK_12160	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PSMK_12210	COG0559	Belongs to the binding-protein-dependent transport system permease family
PSMK_12230	COG0410	ABC transporter
PSMK_12260	COG0829	nickel cation binding
PSMK_12290	COG0831	urea catabolic process
PSMK_12290	COG0832	Belongs to the urease beta subunit family
PSMK_12310	COG0443	Heat shock 70 kDa protein
PSMK_12320	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PSMK_12360	COG0423	glycine-tRNA ligase activity
PSMK_12390	COG0275	rRNA processing
PSMK_12400	COG0284	orotidine-5'-phosphate decarboxylase activity
PSMK_12430	COG1136	(ABC) transporter
PSMK_12460	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PSMK_12470	COG0335	large ribosomal subunit rRNA binding
PSMK_12480	COG1028	Short-chain dehydrogenase reductase Sdr
PSMK_12500	COG0513	Belongs to the DEAD box helicase family
PSMK_12520	COG0354	folic acid binding
PSMK_12530	COG0126	phosphoglycerate kinase activity
PSMK_12550	COG1192	Involved in chromosome partitioning
PSMK_12580	COG0668	transmembrane transport
PSMK_12590	COG0460	homoserine dehydrogenase
PSMK_12610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PSMK_12620	COG0516	GMP reductase activity
PSMK_12620	COG0517	IMP dehydrogenase activity
PSMK_12640	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSMK_12660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PSMK_12680	COG0667	Aldo Keto reductase
PSMK_12690	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PSMK_12690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PSMK_12800	COG0363	glucosamine-6-phosphate deaminase activity
PSMK_12840	COG1649	PFAM Uncharacterised BCR, COG1649
PSMK_12900	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PSMK_12960	COG1609	Transcriptional regulator
PSMK_13010	COG1175	transmembrane transport
PSMK_13020	COG0395	ABC-type sugar transport system, permease component
PSMK_13120	COG0305	Participates in initiation and elongation during chromosome replication
PSMK_13130	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PSMK_13160	COG0328	RNA-DNA hybrid ribonuclease activity
PSMK_13160	COG3341	Caulimovirus viroplasmin
PSMK_13170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PSMK_13180	COG0793	Belongs to the peptidase S41A family
PSMK_13240	COG0174	glutamine synthetase
PSMK_13280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PSMK_13290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSMK_13300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSMK_13330	COG0010	Belongs to the arginase family
PSMK_13340	COG0375	protein maturation
PSMK_13350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PSMK_13360	COG2897	thiosulfate sulfurtransferase activity
PSMK_13390	COG1858	cytochrome C peroxidase
PSMK_13440	COG4956	integral membrane protein (PIN domain superfamily)
PSMK_13450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PSMK_13470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PSMK_13470	COG3323	Protein of unknown function (DUF1653)
PSMK_13560	COG0037	tRNA processing
PSMK_13570	COG1132	(ABC) transporter
PSMK_13590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSMK_13590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PSMK_13590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PSMK_13600	COG0514	ATP-dependent DNA helicase (RecQ)
PSMK_13610	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
PSMK_13620	COG1215	transferase activity, transferring glycosyl groups
PSMK_13640	COG0297	glycogen (starch) synthase activity
PSMK_13650	COG1216	Glycosyl transferase, family 2
PSMK_13650	COG0463	Glycosyl transferase, family 2
PSMK_13700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PSMK_13700	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PSMK_13720	COG2205	protein histidine kinase activity
PSMK_13730	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PSMK_13760	COG0804	urea catabolic process
PSMK_13860	COG0195	Participates in both transcription termination and antitermination
PSMK_13870	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PSMK_13910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PSMK_13920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PSMK_14060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PSMK_14080	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PSMK_14090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PSMK_14100	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PSMK_14110	COG4948	Mandelate Racemase Muconate Lactonizing
PSMK_14120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PSMK_14140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PSMK_14160	COG2022	thiamine diphosphate biosynthetic process
PSMK_14220	COG1796	DNA polymerase
PSMK_14220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PSMK_14240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PSMK_14250	COG0557	exoribonuclease II activity
PSMK_14290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PSMK_14390	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PSMK_14390	COG2199	diguanylate cyclase activity
PSMK_14460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PSMK_14480	COG4535	Mg2 and Co2 transporter CorC
PSMK_14490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PSMK_14520	COG1652	LysM domain
PSMK_14570	COG0646	methionine synthase
PSMK_14570	COG1410	methionine synthase
PSMK_14580	COG0646	methionine synthase
PSMK_14580	COG1410	methionine synthase
PSMK_14590	COG1968	undecaprenyl-diphosphatase activity
PSMK_14660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PSMK_14720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PSMK_14740	COG1131	(ABC) transporter
PSMK_14760	COG0488	(ABC) transporter
PSMK_14810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PSMK_14840	COG0303	'Molybdopterin
PSMK_14850	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
PSMK_14870	COG0667	Aldo Keto reductase
PSMK_14890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PSMK_14910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSMK_14950	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PSMK_14960	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PSMK_14960	COG1519	Transferase
PSMK_14990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PSMK_15030	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PSMK_15050	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PSMK_15140	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PSMK_15190	COG1070	Carbohydrate kinase
PSMK_15210	COG0673	inositol 2-dehydrogenase activity
PSMK_15220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSMK_15240	COG4124	Belongs to the glycosyl hydrolase 26 family
PSMK_15250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PSMK_15290	COG0811	peptide transport
PSMK_15330	COG0114	fumarate hydratase activity
PSMK_15340	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PSMK_15360	COG0793	Belongs to the peptidase S41A family
PSMK_15370	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PSMK_15390	COG0544	peptidyl-prolyl cis-trans isomerase activity
PSMK_15400	COG4325	translation initiation factor activity
PSMK_15430	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PSMK_15490	COG1007	ATP synthesis coupled electron transport
PSMK_15500	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSMK_15520	COG0713	ATP synthesis coupled electron transport
PSMK_15530	COG0839	Belongs to the complex I subunit 6 family
PSMK_15580	COG1121	(ABC) transporter
PSMK_15600	COG0523	cobalamin synthesis protein
PSMK_15640	COG1131	(ABC) transporter
PSMK_15730	COG0653	protein targeting
PSMK_15760	COG0071	Belongs to the small heat shock protein (HSP20) family
PSMK_15810	COG0159	tryptophan synthase activity
PSMK_15840	COG0134	indole-3-glycerol-phosphate synthase activity
PSMK_15910	COG0708	Exodeoxyribonuclease III
PSMK_15970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PSMK_15990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PSMK_16070	COG1288	antiporter activity
PSMK_16120	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PSMK_16160	COG0359	binds to the 23S rRNA
PSMK_16170	COG0629	single-stranded DNA binding
PSMK_16190	COG0736	holo-[acyl-carrier-protein] synthase activity
PSMK_16220	COG0436	Aminotransferase
PSMK_16230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PSMK_16250	COG0215	cysteine-tRNA ligase activity
PSMK_16260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PSMK_16290	COG3250	beta-galactosidase activity
PSMK_16320	COG1063	alcohol dehydrogenase
PSMK_16330	COG0667	Aldo Keto reductase
PSMK_16360	COG3119	arylsulfatase activity
PSMK_16380	COG4589	Belongs to the CDS family
PSMK_16440	COG1612	heme a metabolic process
PSMK_16450	COG0109	protoheme IX farnesyltransferase activity
PSMK_16510	COG0653	protein targeting
PSMK_16520	COG1516	flagellar protein fliS
PSMK_16570	COG4251	negative regulation of phosphorylation
PSMK_16580	COG2204	response regulator
PSMK_16610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PSMK_16620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSMK_16630	COG0649	NAD binding
PSMK_16670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PSMK_16700	COG1678	Uncharacterized ACR, COG1678
PSMK_16760	COG1090	epimerase
PSMK_16840	COG0497	DNA recombination
PSMK_16980	COG2226	methyltransferase
PSMK_16990	COG4636	protein conserved in cyanobacteria
PSMK_17020	COG0307	riboflavin synthase, alpha
PSMK_17040	COG0535	radical SAM domain protein
PSMK_17150	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PSMK_17160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PSMK_17190	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PSMK_17220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSMK_17230	COG5002	protein histidine kinase activity
PSMK_17240	COG0165	Argininosuccinate lyase
PSMK_17260	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PSMK_17270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PSMK_17280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PSMK_17340	COG3932	Exopolysaccharide synthesis, ExoD
PSMK_17370	COG0464	growth
PSMK_17400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PSMK_17420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PSMK_17450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PSMK_17470	COG2204	response regulator
PSMK_17480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PSMK_17500	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PSMK_17530	COG1702	phosphate starvation-inducible protein PhoH
PSMK_17540	COG1480	7TM receptor with intracellular HD hydrolase
PSMK_17580	COG1012	belongs to the aldehyde dehydrogenase family
PSMK_17610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PSMK_17620	COG1360	Flagellar Motor Protein
PSMK_17640	COG1045	serine acetyltransferase
PSMK_17680	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PSMK_17760	COG1525	nuclease
PSMK_17790	COG1131	(ABC) transporter
PSMK_17800	COG0783	Belongs to the Dps family
PSMK_17810	COG0174	glutamine synthetase
PSMK_17830	COG3833	ABC-type maltose transport systems, permease component
PSMK_17840	COG1175	transmembrane transport
PSMK_17890	COG3119	arylsulfatase activity
PSMK_17950	COG2186	Transcriptional regulator
PSMK_17970	COG2211	Major facilitator Superfamily
PSMK_17980	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PSMK_18060	COG2186	Transcriptional regulator
PSMK_18070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PSMK_18090	COG1013	pyruvate-flavodoxin oxidoreductase activity
PSMK_18100	COG0740	serine-type endopeptidase activity
PSMK_18180	COG0438	transferase activity, transferring glycosyl groups
PSMK_18190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PSMK_18210	COG1215	transferase activity, transferring glycosyl groups
PSMK_18220	COG0488	(ABC) transporter
PSMK_18240	COG0756	dUTP diphosphatase activity
PSMK_18260	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PSMK_18300	COG3023	N-Acetylmuramoyl-L-alanine amidase
PSMK_18310	COG1177	transmembrane transport
PSMK_18330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PSMK_18340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PSMK_18390	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PSMK_18400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PSMK_18410	COG0180	Tryptophanyl-tRNA synthetase
PSMK_18430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PSMK_18470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PSMK_18480	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PSMK_18490	COG1722	exodeoxyribonuclease VII activity
PSMK_18500	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PSMK_18520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PSMK_18550	COG1376	ErfK ybiS ycfS ynhG family protein
PSMK_18560	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
PSMK_18610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PSMK_18610	COG0674	pyruvate-flavodoxin oxidoreductase activity
PSMK_18640	COG0415	Belongs to the DNA photolyase family
PSMK_18670	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PSMK_18730	COG0673	inositol 2-dehydrogenase activity
PSMK_18740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PSMK_18750	COG3118	belongs to the thioredoxin family
PSMK_18760	COG5001	Diguanylate cyclase
PSMK_18760	COG4251	negative regulation of phosphorylation
PSMK_18760	COG3706	GGDEF domain
PSMK_18760	COG2203	Gaf domain
PSMK_18770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PSMK_18840	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PSMK_18850	COG0501	Belongs to the peptidase M48B family
PSMK_18860	COG0352	thiamine-phosphate diphosphorylase activity
PSMK_18880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PSMK_18890	COG5001	Diguanylate cyclase
PSMK_18890	COG3300	MHYT domain
PSMK_18900	COG2205	protein histidine kinase activity
PSMK_18910	COG0667	Aldo Keto reductase
PSMK_18930	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PSMK_18950	COG0028	Belongs to the TPP enzyme family
PSMK_19120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PSMK_19140	COG4149	molybdate abc transporter
PSMK_19150	COG1570	exodeoxyribonuclease VII activity
PSMK_19170	COG0556	nucleotide-excision repair
PSMK_19190	COG3250	beta-galactosidase activity
PSMK_19260	COG1546	Belongs to the CinA family
PSMK_19260	COG1058	Belongs to the CinA family
PSMK_19270	COG4464	protein tyrosine phosphatase activity
PSMK_19340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PSMK_19360	COG0254	rRNA binding
PSMK_19400	COG1691	(AIR) carboxylase
PSMK_19440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PSMK_19450	COG0573	inorganic phosphate transmembrane transporter activity
PSMK_19460	COG0581	inorganic phosphate transmembrane transporter activity
PSMK_19470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PSMK_19510	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSMK_19520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PSMK_19530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PSMK_19550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PSMK_19690	COG0673	inositol 2-dehydrogenase activity
PSMK_19710	COG0438	transferase activity, transferring glycosyl groups
PSMK_19750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PSMK_19780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSMK_19780	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PSMK_19820	COG0459	protein refolding
PSMK_19830	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PSMK_19840	COG0459	protein refolding
PSMK_19850	COG0484	heat shock protein binding
PSMK_19860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PSMK_19980	COG0666	response to abiotic stimulus
PSMK_20020	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PSMK_20040	COG2943	transferase activity, transferring hexosyl groups
PSMK_20050	COG0564	pseudouridine synthase activity
PSMK_20090	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PSMK_20100	COG4555	ABC transporter
PSMK_20130	COG0047	phosphoribosylformylglycinamidine synthase activity
PSMK_20150	COG0616	signal peptide processing
PSMK_20160	COG0247	lactate metabolic process
PSMK_20160	COG0277	FAD linked oxidase domain protein
PSMK_20180	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PSMK_20190	COG1929	Belongs to the glycerate kinase type-1 family
PSMK_20220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PSMK_20230	COG1459	type II secretion system
PSMK_20300	COG0746	molybdenum cofactor guanylyltransferase activity
PSMK_20310	COG0315	cyclic pyranopterin monophosphate synthase activity
PSMK_20310	COG0521	Mo-molybdopterin cofactor biosynthetic process
PSMK_20330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSMK_20330	COG1116	anion transmembrane transporter activity
PSMK_20350	COG0243	molybdopterin cofactor binding
PSMK_20370	COG1116	anion transmembrane transporter activity
PSMK_20380	COG1116	anion transmembrane transporter activity
PSMK_20390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSMK_20400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSMK_20400	COG1116	anion transmembrane transporter activity
PSMK_20410	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSMK_20420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PSMK_20440	COG0493	'glutamate synthase
PSMK_20460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PSMK_20470	COG0714	Associated with various cellular activities
PSMK_20480	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PSMK_20510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PSMK_20540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PSMK_20580	COG1181	Belongs to the D-alanine--D-alanine ligase family
PSMK_20610	COG3494	Protein of unknown function (DUF1009)
PSMK_20630	COG1127	ABC transporter
PSMK_20710	COG0587	DNA-directed DNA polymerase activity
PSMK_20720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PSMK_20730	COG1174	glycine betaine transport
PSMK_20740	COG0517	IMP dehydrogenase activity
PSMK_20740	COG1125	glycine betaine transport
PSMK_20760	COG0196	riboflavin kinase activity
PSMK_20780	COG1199	ATP-dependent helicase activity
PSMK_20790	COG1448	Aminotransferase
PSMK_20800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PSMK_20810	COG0673	inositol 2-dehydrogenase activity
PSMK_20820	COG0438	transferase activity, transferring glycosyl groups
PSMK_20830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PSMK_20910	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PSMK_20940	COG0745	RESPONSE REGULATOR receiver
PSMK_20940	COG3706	GGDEF domain
PSMK_20970	COG0072	phenylalanine-tRNA ligase activity
PSMK_21000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSMK_21030	COG0439	Biotin carboxylase
PSMK_21040	COG0511	ligase activity, forming carbon-carbon bonds
PSMK_21060	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PSMK_21080	COG0006	proline dipeptidase activity
PSMK_21100	COG2009	succinate dehydrogenase
PSMK_21110	COG1053	succinate dehydrogenase
PSMK_21130	COG0784	Response regulator, receiver
PSMK_21140	COG4251	negative regulation of phosphorylation
PSMK_21150	COG1674	ftsk spoiiie
PSMK_21210	COG0175	sulfate reduction
PSMK_21220	COG0463	Glycosyl transferase, family 2
PSMK_21230	COG0488	(ABC) transporter
PSMK_21250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PSMK_21270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PSMK_21280	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PSMK_21290	COG1028	Short-chain dehydrogenase reductase Sdr
PSMK_21310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PSMK_21320	COG0187	DNA topoisomerase II activity
PSMK_21330	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSMK_21340	COG0052	Belongs to the universal ribosomal protein uS2 family
PSMK_21350	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PSMK_21380	COG0585	pseudouridine synthase activity
PSMK_21400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSMK_21400	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSMK_21420	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PSMK_21440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PSMK_21460	COG0724	RNA recognition motif
PSMK_21480	COG2823	Periplasmic or secreted lipoprotein
PSMK_21480	COG1652	LysM domain
PSMK_21540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSMK_21550	COG3273	potassium ion transport
PSMK_21550	COG0471	metal ion transport
PSMK_21580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PSMK_21590	COG0346	lactoylglutathione lyase activity
PSMK_21610	COG2814	Major facilitator Superfamily
PSMK_21650	COG1582	Flagellar protein (FlbD)
PSMK_21730	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PSMK_21750	COG1677	Flagellar hook-basal body complex protein FliE
PSMK_21790	COG4191	Histidine kinase
PSMK_21800	COG0436	Aminotransferase
PSMK_21820	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PSMK_21840	COG1408	metallophosphoesterase
PSMK_21850	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PSMK_21860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PSMK_21870	COG0659	secondary active sulfate transmembrane transporter activity
PSMK_21920	COG0436	Aminotransferase
PSMK_21930	COG1127	ABC transporter
PSMK_21940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PSMK_22000	COG0129	dihydroxy-acid dehydratase activity
PSMK_22010	COG0142	geranyltranstransferase activity
PSMK_22020	COG2204	response regulator
PSMK_22060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PSMK_22070	COG0167	dihydroorotate dehydrogenase activity
PSMK_22120	COG0018	arginyl-trna synthetase
PSMK_22160	COG0519	Catalyzes the synthesis of GMP from XMP
PSMK_22160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PSMK_22170	COG0131	Imidazoleglycerol-phosphate dehydratase
PSMK_22180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PSMK_22190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PSMK_22250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PSMK_22260	COG0367	asparagine synthase
PSMK_22290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PSMK_22310	COG0045	succinate-CoA ligase (ADP-forming) activity
PSMK_22360	COG0489	protein tyrosine kinase activity
PSMK_22370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSMK_22380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PSMK_22390	COG0268	Binds directly to 16S ribosomal RNA
PSMK_22400	COG0233	cytoplasmic translational termination
PSMK_22430	COG2217	Heavy metal translocating P-type atpase
PSMK_22480	COG1937	Protein conserved in bacteria
PSMK_22510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSMK_22550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSMK_22560	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PSMK_22580	COG0745	RESPONSE REGULATOR receiver
PSMK_22590	COG4191	Histidine kinase
PSMK_22630	COG1086	Polysaccharide biosynthesis protein
PSMK_22670	COG1272	protein, Hemolysin III
PSMK_22730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PSMK_22740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSMK_22750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PSMK_22760	COG1028	Short-chain dehydrogenase reductase Sdr
PSMK_22770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PSMK_22790	COG1191	sigma factor activity
PSMK_22820	COG0455	bacterial-type flagellum organization
PSMK_22830	COG1419	protein localization to endoplasmic reticulum
PSMK_22840	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PSMK_22870	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PSMK_22890	COG0681	Belongs to the peptidase S26 family
PSMK_22900	COG0440	acetolactate synthase activity
PSMK_22910	COG0698	ribose 5-phosphate isomerase
PSMK_22930	COG3842	ATPase activity
PSMK_22970	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSMK_22980	COG0673	inositol 2-dehydrogenase activity
PSMK_22990	COG0148	phosphopyruvate hydratase activity
PSMK_23010	COG0138	bifunctional purine biosynthesis protein purh
PSMK_23020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PSMK_23040	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PSMK_23080	COG2239	Acts as a magnesium transporter
PSMK_23090	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PSMK_23100	COG0019	diaminopimelate decarboxylase activity
PSMK_23120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSMK_23140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PSMK_23170	COG0571	ribonuclease III activity
PSMK_23200	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PSMK_23220	COG3265	gluconokinase activity
PSMK_23250	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PSMK_23270	COG0569	domain protein
PSMK_23280	COG0688	phosphatidylethanolamine metabolic process
PSMK_23310	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PSMK_23320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PSMK_23350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PSMK_23360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PSMK_23380	COG2200	EAL domain
PSMK_23400	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PSMK_23410	COG2326	polyphosphate kinase activity
PSMK_23420	COG0187	DNA topoisomerase II activity
PSMK_23440	COG2723	6-phospho-beta-galactosidase activity
PSMK_23500	COG1684	flagellar biosynthetic protein fliR
PSMK_23510	COG1987	bacterial-type flagellum assembly
PSMK_23520	COG1338	Plays a role in the flagellum-specific transport system
PSMK_23540	COG1776	CheC inhibitor of MCP methylation
PSMK_23540	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PSMK_23610	COG0444	Belongs to the ABC transporter superfamily
PSMK_23640	COG1862	Preprotein translocase
PSMK_23650	COG0343	queuine tRNA-ribosyltransferase activity
PSMK_23660	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PSMK_23660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PSMK_23710	COG0659	secondary active sulfate transmembrane transporter activity
PSMK_23720	COG0673	inositol 2-dehydrogenase activity
PSMK_23740	COG0203	ribosomal protein L17
PSMK_23760	COG0202	RNA polymerase activity
PSMK_23770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PSMK_23780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PSMK_23790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PSMK_23800	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PSMK_23810	COG0483	inositol monophosphate 1-phosphatase activity
PSMK_23820	COG0481	GTPase activity
PSMK_23890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PSMK_23910	COG0519	Catalyzes the synthesis of GMP from XMP
PSMK_23910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PSMK_24000	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PSMK_24020	COG1543	Belongs to the glycosyl hydrolase 57 family
PSMK_24040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PSMK_24070	COG4166	transmembrane transport
PSMK_24080	COG0601	transmembrane transport
PSMK_24110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PSMK_24120	COG1966	Carbon starvation protein
PSMK_24140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSMK_24160	COG1674	ftsk spoiiie
PSMK_24180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PSMK_24190	COG0242	peptide deformylase activity
PSMK_24200	COG0776	regulation of translation
PSMK_24220	COG3546	catalase activity
PSMK_24250	COG1252	NADH dehydrogenase
PSMK_24310	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PSMK_24340	COG0515	serine threonine protein kinase
PSMK_24340	COG2815	serine threonine protein kinase
PSMK_24350	COG2895	sulfate adenylyltransferase (ATP) activity
PSMK_24350	COG0529	Catalyzes the synthesis of activated sulfate
PSMK_24360	COG0175	sulfate reduction
PSMK_24370	COG3437	response regulator, receiver
PSMK_24420	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PSMK_24440	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PSMK_24450	COG0085	RNA polymerase activity
PSMK_24470	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PSMK_24480	COG1902	pentaerythritol trinitrate reductase activity
PSMK_24490	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PSMK_24540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PSMK_24550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PSMK_24570	COG1530	ribonuclease E activity
PSMK_24580	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PSMK_24590	COG0750	zinc metalloprotease
PSMK_24620	COG4232	protein-disulfide reductase activity
PSMK_24640	COG0133	tryptophan synthase activity
PSMK_24680	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PSMK_24690	COG2813	Specifically methylates the guanine in position
PSMK_24690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSMK_24730	COG1840	ABC-type Fe3 transport system, periplasmic component
PSMK_24820	COG1595	DNA-templated transcription, initiation
PSMK_24880	COG0363	glucosamine-6-phosphate deaminase activity
PSMK_24910	COG1785	Belongs to the alkaline phosphatase family
PSMK_24920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PSMK_24940	COG0445	tRNA wobble uridine modification
PSMK_24960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSMK_24970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PSMK_24980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PSMK_24990	COG4221	oxidoreductase activity
PSMK_25030	COG0492	ferredoxin-NADP+ reductase activity
PSMK_25050	COG1305	Transglutaminase-like
PSMK_25060	COG2308	Evidence 4 Homologs of previously reported genes of
PSMK_25080	COG0601	transmembrane transport
PSMK_25120	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PSMK_25130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PSMK_25180	COG2233	PERMEase
PSMK_25250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PSMK_25310	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PSMK_25310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PSMK_25340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PSMK_25380	COG1175	transmembrane transport
PSMK_25390	COG0395	ABC-type sugar transport system, permease component
PSMK_25400	COG1802	Transcriptional regulator
PSMK_25470	COG4948	Mandelate Racemase Muconate Lactonizing
PSMK_25480	COG1012	belongs to the aldehyde dehydrogenase family
PSMK_25490	COG1028	Short-chain dehydrogenase reductase Sdr
PSMK_25500	COG1063	alcohol dehydrogenase
PSMK_25520	COG0469	pyruvate kinase activity
PSMK_25540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PSMK_25560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PSMK_25610	COG2096	Adenosyltransferase
PSMK_25630	COG1469	GTP cyclohydrolase I activity
PSMK_25690	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PSMK_25700	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PSMK_25700	COG0517	IMP dehydrogenase activity
PSMK_25760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PSMK_25770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PSMK_25800	COG0714	Associated with various cellular activities
PSMK_25820	COG1131	(ABC) transporter
PSMK_25910	COG1131	(ABC) transporter
PSMK_25930	COG5001	Diguanylate cyclase
PSMK_25930	COG3300	MHYT domain
PSMK_25940	COG0791	NLP P60 protein
PSMK_25960	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PSMK_26010	COG0113	porphobilinogen synthase activity
PSMK_26080	COG1643	Atp-dependent helicase
PSMK_26140	COG1606	tRNA processing
PSMK_26160	COG3869	Catalyzes the specific phosphorylation of arginine residues in
PSMK_26170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PSMK_26200	COG0493	'glutamate synthase
PSMK_26210	COG0070	glutamate synthase
PSMK_26210	COG0067	glutamate synthase
PSMK_26210	COG0069	glutamate synthase activity
PSMK_26220	COG0583	DNA-binding transcription factor activity
PSMK_26260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PSMK_26270	COG2835	tetraacyldisaccharide 4'-kinase activity
PSMK_26280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSMK_26330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PSMK_26340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PSMK_26350	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PSMK_26360	COG0193	aminoacyl-tRNA hydrolase activity
PSMK_26370	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PSMK_26380	COG0107	imidazoleglycerol-phosphate synthase activity
PSMK_26420	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PSMK_26450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PSMK_26460	COG0194	GDP metabolic process
PSMK_26500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSMK_26510	COG0698	ribose 5-phosphate isomerase
PSMK_26530	COG0321	lipoyl(octanoyl) transferase activity
PSMK_26540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PSMK_26560	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PSMK_26570	COG0049	tRNA binding
PSMK_26590	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PSMK_26610	COG4786	Flagellar basal body rod
PSMK_26630	COG4786	Flagellar basal body rod
PSMK_26660	COG0539	negative regulation of cytoplasmic translation
PSMK_26660	COG2183	response to ionizing radiation
PSMK_26690	COG1166	arginine decarboxylase activity
PSMK_26710	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PSMK_26720	COG4284	Utp--glucose-1-phosphate uridylyltransferase
PSMK_26740	COG4566	intracellular signal transduction
PSMK_26760	COG1999	signal sequence binding
PSMK_26770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PSMK_26830	COG0606	chelatase, subunit chli
PSMK_26860	COG0802	atpase or kinase
PSMK_26870	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PSMK_26900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PSMK_27000	COG1994	Peptidase M50
PSMK_27030	COG1295	ribonuclease BN
PSMK_27100	COG0594	ribonuclease P activity
PSMK_27110	COG1295	ribonuclease BN
PSMK_27140	COG0564	pseudouridine synthase activity
PSMK_27150	COG1609	Transcriptional regulator
PSMK_27260	COG5002	protein histidine kinase activity
PSMK_27360	COG4536	flavin adenine dinucleotide binding
PSMK_27370	COG4535	Mg2 and Co2 transporter CorC
PSMK_27380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PSMK_27420	COG0504	CTP synthase activity
PSMK_27490	COG0166	Belongs to the GPI family
PSMK_27560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PSMK_27600	COG0101	tRNA pseudouridine synthase activity
PSMK_27610	COG0438	transferase activity, transferring glycosyl groups
PSMK_27650	COG0513	Belongs to the DEAD box helicase family
PSMK_27680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PSMK_27690	COG2258	MOSC domain
PSMK_27790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSMK_27800	COG0346	lactoylglutathione lyase activity
PSMK_27830	COG2706	6-phosphogluconolactonase activity
PSMK_27840	COG0346	lactoylglutathione lyase activity
PSMK_27870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PSMK_27900	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PSMK_27940	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PSMK_27990	COG1136	(ABC) transporter
PSMK_28000	COG0745	RESPONSE REGULATOR receiver
PSMK_28050	COG2165	general secretion pathway protein
PSMK_28090	COG1459	type II secretion system
PSMK_28120	COG2205	protein histidine kinase activity
PSMK_28140	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PSMK_28160	COG0501	Belongs to the peptidase M48B family
PSMK_28170	COG1704	LemA family
PSMK_28200	COG4974	Belongs to the 'phage' integrase family
PSMK_28270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PSMK_28290	COG2003	Belongs to the UPF0758 family
PSMK_28350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PSMK_28390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PSMK_28390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PSMK_28410	COG4968	Prepilin-type N-terminal cleavage methylation domain
PSMK_28440	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PSMK_28450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PSMK_28460	COG0740	serine-type endopeptidase activity
PSMK_28490	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PSMK_28510	COG0733	neurotransmitter:sodium symporter activity
PSMK_28590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PSMK_28600	COG0681	Belongs to the peptidase S26 family
PSMK_28720	COG0598	Magnesium transport protein CorA
PSMK_28730	COG1070	Carbohydrate kinase
PSMK_28780	COG1028	Short-chain dehydrogenase reductase Sdr
PSMK_28800	COG0640	Transcriptional regulator
PSMK_28930	COG3459	Glycosyltransferase 36 associated
PSMK_28940	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PSMK_28950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSMK_28980	COG0024	Methionine aminopeptidase
PSMK_29000	COG0200	Binds to the 23S rRNA
PSMK_29010	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PSMK_29020	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PSMK_29030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PSMK_29040	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PSMK_29050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PSMK_29060	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PSMK_29070	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PSMK_29080	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PSMK_29090	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PSMK_29100	COG0255	Belongs to the universal ribosomal protein uL29 family
PSMK_29110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PSMK_29120	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PSMK_29130	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PSMK_29150	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PSMK_29160	COG0089	rRNA binding
PSMK_29170	COG0088	Forms part of the polypeptide exit tunnel
PSMK_29180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PSMK_29190	COG0051	transcription antitermination factor activity, RNA binding
PSMK_29220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PSMK_29260	COG0473	3-isopropylmalate dehydrogenase activity
PSMK_29270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PSMK_29320	COG1028	Short-chain dehydrogenase reductase Sdr
PSMK_29320	COG3347	Dehydrogenase
PSMK_29330	COG1349	DNA-binding transcription factor activity
PSMK_29340	COG4952	isomerase
PSMK_29360	COG0191	fructose-bisphosphate aldolase activity
PSMK_29390	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PSMK_29450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PSMK_29480	COG1845	cytochrome c oxidase, subunit III
PSMK_29510	COG0577	efflux transmembrane transporter activity
PSMK_29510	COG1136	(ABC) transporter
PSMK_29560	COG0617	tRNA 3'-terminal CCA addition
PSMK_29570	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PSMK_29590	COG4566	intracellular signal transduction
PSMK_29620	COG0742	ribosomal rna small subunit methyltransferase
PSMK_29630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PSMK_29670	COG0859	PFAM glycosyl transferase family 9
PSMK_29680	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PSMK_29700	COG0667	Aldo Keto reductase
PSMK_29720	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PSMK_29730	COG4221	oxidoreductase activity
PSMK_29750	COG0442	prolyl-tRNA aminoacylation
PSMK_29800	COG0123	including yeast histone deacetylase and acetoin utilization protein
PSMK_29810	COG2166	iron-sulfur cluster assembly
PSMK_29820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PSMK_29840	COG2089	acid synthase
PSMK_29870	COG2160	L-arabinose isomerase activity
PSMK_29910	COG0322	excinuclease ABC activity
PSMK_29920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSMK_29970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PSMK_29990	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PSMK_30020	COG1192	Involved in chromosome partitioning
PSMK_30040	COG1663	tetraacyldisaccharide 4'-kinase activity
PSMK_30130	COG0745	RESPONSE REGULATOR receiver
PSMK_30170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PSMK_30180	COG1069	ribulokinase activity
PSMK_30220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PSMK_30230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSMK_30270	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
PSMK_30300	COG0546	phosphoglycolate phosphatase activity
PSMK_30320	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PSMK_30350	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PSMK_30360	COG0527	aspartate kinase activity
PSMK_30390	COG1361	Conserved repeat domain
PSMK_30400	COG0484	heat shock protein binding
PSMK_30410	COG0542	response to heat
PSMK_30440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PSMK_30450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PSMK_30460	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PSMK_30480	COG1335	isochorismatase
PSMK_30490	COG1397	ADP-ribosylglycohydrolase
PSMK_30500	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PSMK_30510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PSMK_30540	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PSMK_30550	COG2351	hydroxyisourate hydrolase activity
PSMK_30580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PSMK_30620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PSMK_30650	COG2080	2 iron, 2 sulfur cluster binding
PSMK_30660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PSMK_30680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PSMK_30730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PSMK_30750	COG1030	water channel activity
PSMK_30760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PSMK_30770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSMK_30780	COG1196	nuclear chromosome segregation
PSMK_30790	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PSMK_30800	COG1254	Belongs to the acylphosphatase family
PSMK_30830	COG2151	metal-sulfur cluster biosynthetic enzyme
PSMK_30870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSMK_30910	COG0803	Belongs to the bacterial solute-binding protein 9 family
PSMK_30920	COG1121	(ABC) transporter
PSMK_30930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PSMK_30940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PSMK_30980	COG0655	NAD(P)H dehydrogenase (quinone) activity
PSMK_31070	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PSMK_31080	COG0509	glycine decarboxylation via glycine cleavage system
PSMK_31120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PSMK_31130	COG0546	phosphoglycolate phosphatase activity
PSMK_31140	COG1160	GTP binding
PSMK_31180	COG0667	Aldo Keto reductase
PSMK_31260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PSMK_31350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PSMK_31500	COG1639	'signal transduction protein
PSMK_31510	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PSMK_31510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PSMK_31520	COG0473	3-isopropylmalate dehydrogenase activity
PSMK_31540	COG2247	cell wall binding repeat
PSMK_31540	COG2385	sporulation resulting in formation of a cellular spore
PSMK_31600	COG3250	beta-galactosidase activity
PSMK_31610	COG0492	ferredoxin-NADP+ reductase activity
PSMK_31640	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSMK_31660	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PSMK_31690	COG1215	transferase activity, transferring glycosyl groups
PSMK_31710	COG0205	6-phosphofructokinase activity
PSMK_31740	COG0676	glucose-6-phosphate 1-epimerase activity
PSMK_31830	COG1533	DNA photolyase activity
PSMK_31860	COG3328	transposase activity
PSMK_31900	COG0459	protein refolding
PSMK_31910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PSMK_31950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PSMK_32000	COG2137	regulation of response to DNA damage stimulus
PSMK_32010	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PSMK_32020	COG1253	flavin adenine dinucleotide binding
PSMK_p00120	COG2003	Belongs to the UPF0758 family
PSMK_p00250	COG2132	Multicopper oxidase
PSMK_p00260	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PSMK_p00270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSMK_p00320	COG0723	plastoquinol--plastocyanin reductase activity
PSMK_p00390	COG1937	Protein conserved in bacteria
PSMK_p00470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSMK_p00580	COG4974	Belongs to the 'phage' integrase family
PSMK_p00610	COG2948	multi-organism process
PSMK_p00620	COG3504	Conjugal transfer protein
PSMK_p00630	COG3701	Conjugal transfer protein
PSMK_p00660	COG3451	type IV secretory pathway VirB4
PSMK_p00680	COG3838	Conjugal transfer protein Trbc
PSMK_p00690	COG4962	Type ii secretion system protein e
PSMK_p00770	COG1192	Involved in chromosome partitioning