locus-tag class description AB182_00170 ENOG4105E4C Lytic transglycosylase catalytic AB182_00220 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB182_00260 ENOG4108XS9 dna repair protein AB182_00285 ENOG4105KF5 hemolysin expression-modulating protein AB182_00320 ENOG4107XMK single-stranded DNA-binding protein AB182_00460 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_00520 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_00575 ENOG4108MVM Transposase AB182_00580 ENOG4108ZQS transposase AB182_00595 ENOG4105MVE transcriptional regulator AB182_00800 ENOG4106JVB Replication Protein AB182_00810 ENOG4106CQM replication AB182_00850 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_00980 ENOG4105MDZ Transcriptional activator rfaH AB182_01070 ENOG41074AV Hok/gef family AB182_01075 ENOG4105K4U addiction module toxin, RelE StbE family AB182_01125 ENOG4107Y80 Major Facilitator superfamily AB182_01135 ENOG41061MD high-affinity nickel-transporter AB182_01140 ENOG4108YDI single-species biofilm formation on inanimate substrate AB182_01345 ENOG410624V efflux system protein AB182_01375 ENOG4105DR5 peptidase AB182_01390 ENOG4108YXQ IS66 Orf2 family protein AB182_01395 ENOG4105E5H Transposase AB182_01400 ENOG4105E3B Multicopper oxidase AB182_01405 ENOG4105VR0 copper resistance AB182_01410 ENOG4105JDN Copper resistance protein AB182_01415 ENOG4108PG2 copper resistance AB182_01420 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB182_01425 ENOG4105GR3 Histidine kinase AB182_01450 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A AB182_01455 ENOG4105D58 Diguanylate phosphodiesterase AB182_01465 ENOG410620I Diguanylate cyclase AB182_01470 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_01485 ENOG4105KBH arsR family transcriptional regulator AB182_01490 ENOG4105CAU Arsenical resistance protein, ArsH AB182_01495 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_01500 ENOG4105VUF Transcriptional regulator AB182_01530 ENOG4108ZSJ is1 orf2 AB182_01535 ENOG4105Y3E Modulates RecA activity (By similarity) AB182_01570 ENOG410645W Thiamin biosynthesis protein ThiH AB182_01585 ENOG4105CMM transposase AB182_01590 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_01595 ENOG4108C33 Resolvase AB182_01630 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_01670 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_01685 ENOG4108C33 Resolvase AB182_01695 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_01745 ENOG4105F2I Transposase AB182_01765 ENOG4106JVB Replication Protein AB182_01770 ENOG4105EZN Cobyrinic acid ac-diamide synthase AB182_01775 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB AB182_01825 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_01830 ENOG4105CIS alcohol dehydrogenase AB182_01840 ENOG4105ETE Transcriptional regulator (LacI family AB182_01850 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) AB182_01865 ENOG4108JQ6 ABC transporter AB182_01880 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AB182_02030 ENOG4105K4U addiction module toxin, RelE StbE family AB182_02050 ENOG41085W3 Transposase AB182_02060 ENOG4105DQ6 Transposase AB182_02065 ENOG410698F IS150 protein InsA AB182_02190 ENOG4105DAX Pfam:DUF2983 AB182_02220 ENOG4108M24 von Willebrand factor, type A AB182_02225 ENOG4108M24 von Willebrand factor, type A AB182_02360 ENOG4105C4R Atp-dependent dna helicase AB182_02505 ENOG4106JVB Replication Protein AB182_02530 ENOG4105DFE Dna adenine methylase AB182_02565 ENOG4106JVB Replication Protein AB182_02585 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AB182_02810 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_02825 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) AB182_02930 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_02935 ENOG4105VUF Transcriptional regulator AB182_03015 ENOG4108YX2 DNA-binding protein AB182_03090 ENOG4108C33 Resolvase AB182_03120 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) AB182_03140 ENOG4108R0M Aminoglycoside AB182_03170 ENOG4105DIJ Phosphoethanolamine transferase AB182_03180 ENOG4105GR3 Histidine kinase AB182_03190 ENOG41061MD high-affinity nickel-transporter AB182_03265 ENOG4105CHH sulfate transporter AB182_03275 ENOG4105K89 arsenate reductase AB182_03285 ENOG4105KBH arsR family transcriptional regulator AB182_03290 ENOG4105CAU Arsenical resistance protein, ArsH AB182_03310 ENOG4108I6A alcohol dehydrogenase AB182_03315 ENOG4105EQ2 LysR family Transcriptional regulator AB182_03380 ENOG4108MBK is1 orf2 AB182_03395 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) AB182_03415 ENOG4105T95 Thiol disulfide interChange protein AB182_03430 ENOG4105GMB type VI secretion system effector, hcp1 family AB182_03445 ENOG4105CXN decarboxylase AB182_03450 ENOG4106YYS transcriptional regulatory protein AB182_03455 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism AB182_03460 ENOG4105D2K citrate carrier protein AB182_03465 ENOG4105ERH Fumarylacetoacetate hydrolase AB182_03470 ENOG4105DUA (citrate (pro-3S)-lyase ligase AB182_03475 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) AB182_03480 ENOG4105CI0 Citrate lyase AB182_03485 ENOG4105CHY citrate lyase, alpha AB182_03495 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase AB182_03500 ENOG4105EAA nucleoside AB182_03505 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division AB182_03515 ENOG4105CEN a g-specific adenine glycosylase AB182_03525 ENOG41090ED Protein with unknown function (DUF469) AB182_03530 ENOG4105K33 Periplasmic Protein AB182_03535 ENOG4108KQ5 Integrase catalytic subunit AB182_03540 ENOG4105WDY DNA (cytosine-5-)-methyltransferase AB182_03545 ENOG4105CG6 trap dicarboxylate transporter dctm subunit AB182_03550 ENOG41069H7 transport system small permease component AB182_03555 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit AB182_03560 ENOG4105CSA Coproporphyrinogen iii oxidase AB182_03565 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) AB182_03575 ENOG4108VIA integral membrane protein AB182_03580 ENOG4105DFA alanine racemase domain protein AB182_03585 ENOG4105CZX twitching motility protein AB182_03600 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) AB182_03605 ENOG4108UJU UPF0301 protein AB182_03610 ENOG4105D7Z glutathione synthase AB182_03615 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) AB182_03620 ENOG4105RWS endonuclease I AB182_03625 ENOG4105GPY SprT protein AB182_03645 ENOG4105EFZ amidohydrolase AB182_03670 ENOG4105BZU Histidine kinase AB182_03680 ENOG4107QNK )-transporter AB182_03685 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP AB182_03700 ENOG4108K0D peptidase, M48 AB182_03705 ENOG4105CV1 Transketolase (EC 2.2.1.1) AB182_03710 ENOG4105EPW hflc protein AB182_03720 ENOG4105BZA Phosphoglycerate kinase AB182_03725 ENOG4105D2N Aldolase AB182_03730 ENOG4105D64 Mechanosensitive ion channel AB182_03735 ENOG4108ZUB Lysine exporter protein (Lyse ygga) AB182_03740 ENOG4105MPN Membrane AB182_03745 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) AB182_03750 ENOG4105E66 phosphoriboisomerase A AB182_03755 ENOG4108JQ1 Dehydrogenase AB182_03760 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase AB182_03765 ENOG4107YUN Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) AB182_03775 ENOG4107RAQ aminopeptidase AB182_03780 ENOG4105D0A hydroxylase AB182_03785 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family AB182_03790 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) AB182_03795 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) AB182_03800 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor AB182_03805 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AB182_03810 ENOG4105CS2 ec 3.2.1.21 AB182_03815 ENOG4108Q3X Transcriptional regulator AB182_03825 ENOG4108UT2 hemolysin iii AB182_03830 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) AB182_03840 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB AB182_03845 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) AB182_03850 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB182_03855 ENOG4105T95 Thiol disulfide interChange protein AB182_03860 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) AB182_03870 ENOG4105CRK lysyL-tRNA synthetase AB182_03875 ENOG4108ZEY Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) AB182_03880 ENOG4108UQV Membrane AB182_03885 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase AB182_03890 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) AB182_03895 ENOG4106P55 Transcriptional regulator AB182_03900 ENOG4108K5P (LipO)protein AB182_03930 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) AB182_03935 ENOG4105CKK Glycosyl transferase, family 2 AB182_03950 ENOG4108YXQ IS66 Orf2 family protein AB182_03955 ENOG4105E5H Transposase AB182_03965 ENOG4105CMM transposase AB182_04005 ENOG4106H6R UPF0380 protein AB182_04010 ENOG4105MFG Antirestriction protein AB182_04015 ENOG4108XS9 dna repair protein AB182_04020 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles AB182_04030 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures AB182_04035 ENOG41090WB Transposase is3 is911 AB182_04055 ENOG4105DIA mandelate racemase muconate lactonizing AB182_04060 ENOG4108I5G Major Facilitator superfamily AB182_04070 ENOG4105EQN UPF0261 protein AB182_04080 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AB182_04085 ENOG4108UI1 Probably functions as a manganese efflux pump (By similarity) AB182_04090 ENOG41082CG Protein CrcB homolog AB182_04095 ENOG4105EQX glucarate dehydratase AB182_04105 ENOG4105C5Q Transcriptional regulator AB182_04115 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AB182_04130 ENOG4105EJG cellulose synthase AB182_04135 ENOG4107EEX Cellulose synthase regulator protein AB182_04150 ENOG4105BZU Histidine kinase AB182_04155 ENOG4105BZU Histidine kinase AB182_04160 ENOG4107S5I aldo keto reductase AB182_04165 ENOG4105C28 cystathionine AB182_04180 ENOG4108UMI ABC transporter, permease AB182_04185 ENOG4105D01 (LipO)protein AB182_04190 ENOG4105CHU acetyl-coa acetyltransferase AB182_04200 ENOG4105CHR reductase AB182_04225 ENOG4105RQF LysR family Transcriptional regulator AB182_04230 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) AB182_04240 ENOG4105CK1 PTS System AB182_04245 ENOG4105CS2 ec 3.2.1.21 AB182_04255 ENOG4107YCY Transcriptional regulator AB182_04265 ENOG41060NJ transcriptional regulator AB182_04270 ENOG4105CEY Amp-dependent synthetase and ligase AB182_04275 ENOG4107S74 Lysophospholipid transporter LplT AB182_04280 ENOG4105CPC Aldo Keto reductase AB182_04285 ENOG4105SUV lipoprotein YgdR AB182_04290 ENOG4105EE5 Membrane protein terC AB182_04300 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) AB182_04305 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase AB182_04310 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) AB182_04315 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) AB182_04320 ENOG4105IPU prepilin peptidase dependent protein A AB182_04330 ENOG4105SEN Protein of unknown function (DUF2509) AB182_04335 ENOG4105RVB Prepilin peptidase dependent protein c AB182_04340 ENOG4105DSY exodeoxyribonuclease V, gamma AB182_04345 ENOG4107QXK peptidase AB182_04350 ENOG4107QKA exodeoxyribonuclease V beta AB182_04355 ENOG4107QYX exodeoxyribonuclease v alpha AB182_04360 ENOG4107QZM n-acetylglutamate synthase AB182_04365 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AB182_04385 ENOG4105CA3 membrane-bound lytic murein transglycosylase AB182_04390 ENOG4105CUZ uba thif-type nad fad binding protein AB182_04395 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) AB182_04400 ENOG4105C9B Cysteine desulfurase AB182_04405 ENOG4105M5B (LipO)protein AB182_04410 ENOG4105ETT transcriptional Regulator, LysR family AB182_04415 ENOG4105M08 Membrane AB182_04420 ENOG4105EZ6 Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity) AB182_04430 ENOG4105EJQ L-serine dehydratase AB182_04435 ENOG4105C44 Serine transporter AB182_04440 ENOG4105EWT decarboxylase family AB182_04445 ENOG4107R1K Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) AB182_04450 ENOG4108T6E Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity) AB182_04455 ENOG4105WP7 tRNA pseudouridine synthase C AB182_04460 ENOG4105DR9 pseudouridine synthase AB182_04465 ENOG4105QDK Flavodoxin AB182_04470 ENOG4105DJB Major Facilitator Superfamily AB182_04475 ENOG4105EQX glucarate dehydratase AB182_04480 ENOG4105EQX glucarate dehydratase AB182_04485 ENOG4105BZW Glycerate kinase AB182_04490 ENOG4105BZU Histidine kinase AB182_04495 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) AB182_04500 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AB182_04515 ENOG4105DXN mazG family AB182_04520 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) AB182_04535 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) AB182_04540 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase AB182_04545 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) AB182_04560 ENOG4108RS6 transposase AB182_04575 ENOG4108MXK alkaline phosphatase isozyme conversion AB182_04580 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AB182_04590 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) AB182_04595 ENOG4107UCJ Catalyzes the synthesis of activated sulfate (By similarity) AB182_04600 ENOG4105N0Z inner membrane protein ygbE AB182_04605 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) AB182_04620 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) AB182_04625 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) AB182_04630 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) AB182_04635 ENOG4108K5P (LipO)protein AB182_04645 ENOG4105KZM cytoplasmic protein AB182_04650 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) AB182_04655 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase AB182_04665 ENOG4108Z9K Osmotically inducible protein AB182_04670 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) AB182_04685 ENOG4105CMM transposase AB182_04710 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) AB182_04730 ENOG4105CT4 transporter AB182_04735 ENOG4105DSG hydrolase family 43 AB182_04745 ENOG4105FFC UPF0187 protein AB182_04750 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB182_04790 ENOG4105VXR cytoplasmic protein AB182_04795 ENOG4105F4R Transcriptional regulator mode AB182_04800 ENOG4105C45 hydrogenase expression formation protein (HypE) AB182_04805 ENOG4105CQS hydrogenase expression formation protein HypD AB182_04810 ENOG41083WG hydrogenase assembly chaperone AB182_04815 ENOG4107RSS Hydrogenase accessory protein HypB AB182_04820 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) AB182_04825 ENOG4108MG9 hydrogenase 3 maturation protease AB182_04830 ENOG4105CS2 ec 3.2.1.21 AB182_04835 ENOG4105C5Y PTS System AB182_04840 ENOG4105DDV Transcriptional regulator (LacI family AB182_04845 ENOG4108RC0 Electron transport protein AB182_04850 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB182_04855 ENOG4105C8H hydrogenase maturation protein Hypf AB182_04860 ENOG4107QZF nitrite reductase NADPH large subunit AB182_04865 ENOG4108ESE uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center AB182_04870 ENOG4108JUA Transcriptional regulator AB182_04880 ENOG410804X Transcriptional regulator AB182_04885 ENOG4105J92 DNA-binding transcriptional activator GutM AB182_04890 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase AB182_04895 ENOG4105VI0 Pts system, glucitol sorbitol-specific AB182_04900 ENOG4105DZY Pts system, glucitol sorbitol-specific AB182_04905 ENOG410787A Pts system, glucitol sorbitol-specific AB182_04910 ENOG4105CVE Lytic murein transglycosylase AB182_04915 ENOG4105DIK (ABC) transporter AB182_04920 ENOG4105CC5 ABC transporter AB182_04925 ENOG4107SIG periplasmic solute binding protein AB182_04930 ENOG4107TH8 cina domain protein AB182_04935 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) AB182_04945 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AB182_04950 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) AB182_04980 ENOG4105K3G Periplasmic Protein AB182_04985 ENOG4107VXZ Hydrolase AB182_04990 ENOG4105W39 Membrane AB182_04995 ENOG4105D9M gamma-glutamylcysteine synthetase AB182_05010 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) AB182_05020 ENOG4108V1T peptidylprolyl cis-trans isomerase AB182_05035 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB182_05040 ENOG4105CW7 secretion protein, HlyD family AB182_05045 ENOG4105NTK Transcriptional repressor Mpra AB182_05055 ENOG4105GIJ Glycine betaine AB182_05060 ENOG4108HQS Glycine betaine AB182_05065 ENOG4108IJ7 Glycine betaine AB182_05070 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AB182_05075 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AB182_05085 ENOG4105WAZ (Glutaredoxin-like protein) NrdH AB182_05090 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) AB182_05095 ENOG4108WMJ Protein of unknown function (DUF2002) AB182_05100 ENOG4108RNS Exports L-alanine (By similarity) AB182_05110 ENOG4105VPI YqaE family transport protein AB182_05125 ENOG4105CC0 LysR family Transcriptional regulator AB182_05145 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) AB182_05155 ENOG4108YX2 DNA-binding protein AB182_05185 ENOG4108ZSJ is1 orf2 AB182_05205 ENOG4108Z1B Cyclase dehydrase AB182_05210 ENOG4105VDB UPF0125 protein AB182_05220 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AB182_05225 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) AB182_05240 ENOG4108JU6 CBS domain protein AB182_05245 ENOG4106KVJ cytochrome C assembly protein AB182_05250 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY AB182_05260 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) AB182_05270 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) AB182_05275 ENOG4105ZTC transcriptional activator, Ogr delta AB182_05310 ENOG4105UZW Tail fiber assembly protein AB182_05400 ENOG4105ED4 portal protein AB182_05415 ENOG4105VZ1 Replication Protein AB182_05460 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AB182_05465 ENOG4105EHE chorismate mutase- prephenate dehydrogenase AB182_05475 ENOG4105CQC Prephenate dehydratase AB182_05480 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA AB182_05485 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane AB182_05490 ENOG4105C34 Pseudouridine synthase AB182_05495 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase AB182_05500 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB182_05530 ENOG4105CSH Transporter AB182_05535 ENOG4105T42 (LipO)protein AB182_05540 ENOG4105JIM Phosphatidylserine synthase AB182_05545 ENOG4105CD5 CoA-binding domain protein AB182_05550 ENOG4106IUH DTW domain containing protein AB182_05555 ENOG4105K63 Thioredoxin AB182_05560 ENOG4105EIB trna rrna methyltransferase AB182_05575 ENOG4105CEY Amp-dependent synthetase and ligase AB182_05580 ENOG4105D2S major facilitator superfamily AB182_05585 ENOG41090P5 ferredoxin-like protein AB182_05590 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase AB182_05595 ENOG4105C10 Electron transfer flavoprotein AB182_05600 ENOG4105CV7 Electron transfer flavoprotein AB182_05605 ENOG4105C1G acyl-Coa dehydrogenase AB182_05615 ENOG4105DJB Major Facilitator Superfamily AB182_05630 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) AB182_05640 ENOG4105C1J atp-dependent rna helicase AB182_05650 ENOG4108IYU L-aspartate oxidase AB182_05660 ENOG41069PW sigma-e factor negative regulatory protein AB182_05670 ENOG4105WMJ Positive regulator of sigma E, RseC MucC AB182_05680 ENOG4105C3F Signal peptidase i AB182_05695 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) AB182_05700 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) AB182_05710 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding AB182_05715 ENOG4106G6Q Transcriptional regulator AB182_05720 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate AB182_05730 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB AB182_05735 ENOG4108Z6B deaminase AB182_05740 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) AB182_05745 ENOG4108ETH Formylglycinamide ribotide synthetase AB182_05750 ENOG4107WP9 Histidine kinase AB182_05755 ENOG4108SKK alpha helix protein AB182_05760 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AB182_05765 ENOG4108YZA Nitrogen regulatory protein pii AB182_05770 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AB182_05790 ENOG4108NZE NAGC-like transcriptional regulator AB182_05795 ENOG4107HQ7 repeat protein AB182_05800 ENOG4105FCA ABC transporter periplasmic-binding protein YphF AB182_05805 ENOG4108F37 ATP-binding component of a transport system AB182_05810 ENOG4105CNN ABC, transporter AB182_05815 ENOG4105CPQ Dehydrogenase AB182_05820 ENOG4108ZKT aldose 1-epimerase AB182_05825 ENOG4105D8G Major Facilitator superfamily AB182_05830 ENOG4108MN2 Stationary phase inducible protein CsiE AB182_05835 ENOG41065CD Exported protein AB182_05840 ENOG4105D7X high-affinity nickel-transporter AB182_05845 ENOG4105ECY inositol monophosphatase AB182_05850 ENOG4105CVS RNA methyltransferase TrmH family, group 1 AB182_05855 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family AB182_05860 ENOG4105C3J Cysteine desulfurase AB182_05865 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins AB182_05875 ENOG4108SWN Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity) AB182_05885 ENOG4108ZIT Ferredoxin, 2FE-2S AB182_05890 ENOG4105WVQ Fe-S assembly protein IscX AB182_05895 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) AB182_05900 ENOG4105YYA enhanced serine sensitivity protein SseB AB182_05905 ENOG4108Q3X Transcriptional regulator AB182_05910 ENOG4105KHC sulfurtransferase AB182_05920 ENOG4105CI1 PTS System AB182_05925 ENOG4105DN3 alpha-2-macroglobulin domain protein AB182_05930 ENOG4108JQB penicillin-binding protein 1C AB182_05935 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) AB182_05940 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs AB182_05950 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) AB182_05960 ENOG4105N21 Membrane AB182_05965 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AB182_05970 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) AB182_05975 ENOG4105VPD cellular component movement AB182_05985 ENOG4105D4Y metalloprotease AB182_06000 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AB182_06005 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AB182_06010 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) AB182_06040 ENOG4105E82 cytochrome subunit of dehydrogenase AB182_06045 ENOG4105BZU Histidine kinase AB182_06050 ENOG4105C9X ppx gppa phosphatase AB182_06055 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) AB182_06060 ENOG4108V3E phosphoribosylglycinamide formyltransferase AB182_06065 ENOG4105CXB phosphoribosylaminoimidazole synthetase AB182_06070 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) AB182_06075 ENOG4105C2W permease AB182_06085 ENOG4105K89 arsenate reductase AB182_06090 ENOG4105ERG peptidase m48, ste24p AB182_06095 ENOG4105C02 permease AB182_06100 ENOG4105TMB Formate nitrite transporter AB182_06105 ENOG4108JUA Transcriptional regulator AB182_06110 ENOG4105I6X formate hydrogenlyase maturation AB182_06115 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit AB182_06125 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AB182_06130 ENOG4108JPZ Monovalent cation H antiporter subunit D AB182_06135 ENOG4107WQX hydrogenase 4 membrane subunit AB182_06140 ENOG4105D65 subunit l AB182_06145 ENOG4107TDF Formate hydrogenlyase subunit 4 AB182_06150 ENOG4108JPZ Monovalent cation H antiporter subunit D AB182_06155 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) AB182_06160 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AB182_06165 ENOG4105RH4 Glycine cleavage system transcriptional repressor AB182_06175 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AB182_06180 ENOG4105C8V SAICAR synthetase AB182_06185 ENOG4105CGZ zinc metallopeptidase AB182_06190 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) AB182_06195 ENOG4106KED esterase YpfH AB182_06200 ENOG4105XYK UPF0370 protein AB182_06205 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) AB182_06210 ENOG4105KUZ arsenate reductase AB182_06215 ENOG4105BZS acriflavin resistance protein AB182_06220 ENOG4105BZU Histidine kinase AB182_06225 ENOG4105BZ8 glutamate synthase AB182_06230 ENOG4107VIJ nudix hydrolase AB182_06235 ENOG4108PVD exported protein AB182_06240 ENOG4105CV1 Transketolase (EC 2.2.1.1) AB182_06245 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AB182_06250 ENOG4105C6K Malic enzyme AB182_06260 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase AB182_06270 ENOG4105QZU Inner membrane protein YfeZ AB182_06275 ENOG4105E7K (LipO)protein AB182_06280 ENOG4105EZR dyp-type peroxidase family protein AB182_06285 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein AB182_06290 ENOG4108I5D sulfate abc transporter AB182_06295 ENOG4105ECW sulfate abc transporter AB182_06300 ENOG4108IJ6 ABC transporter AB182_06305 ENOG4105C6T cysteine synthase AB182_06315 ENOG4105C5Y PTS System AB182_06325 ENOG4105KZ7 phosphocarrier protein hpr AB182_06330 ENOG4105C6T cysteine synthase AB182_06335 ENOG4105EXN Sulfate transport protein CysZ AB182_06340 ENOG4107NPY receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity) AB182_06345 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) AB182_06350 ENOG4105VRT cytoplasmic protein AB182_06355 ENOG4105DHU Bile acid AB182_06360 ENOG4108M0I Transcriptional regulator AB182_06395 ENOG4105GXM Putative transcription regulator (DUF1323) AB182_06400 ENOG4105HZG regulatoR AB182_06415 ENOG4108KMM Diguanylate cyclase AB182_06420 ENOG4105D9N nucleoside AB182_06425 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) AB182_06430 ENOG4109076 Conserved Protein AB182_06435 ENOG4105CPC Aldo Keto reductase AB182_06445 ENOG4105CHC glucokinase (EC 2.7.1.2) AB182_06450 ENOG4105DY9 regulatoR AB182_06455 ENOG4108HRK Histidine kinase AB182_06460 ENOG4105CHM Aminotransferase AB182_06470 ENOG4105DTA methyltransferase AB182_06505 ENOG4105BZU Histidine kinase AB182_06525 ENOG4108JJA ABC, transporter AB182_06560 ENOG4107QZV Type I secretion membrane fusion protein AB182_06580 ENOG4105C8Q Methyl-accepting chemotaxis AB182_06615 ENOG4105CMM transposase AB182_06625 ENOG4105DFP Integrase AB182_06650 ENOG4105DFP Integrase AB182_06660 ENOG4105S64 Formate nitrite transporter AB182_06665 ENOG410903C (LipO)protein AB182_06670 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation AB182_06675 ENOG4105KZW UPF0381 protein AB182_06680 ENOG4105CHU acetyl-coa acetyltransferase AB182_06685 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AB182_06690 ENOG4108BY2 phosphohistidine phosphatase AB182_06695 ENOG4108DG9 Smr protein MutS2 AB182_06700 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) AB182_06710 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) AB182_06715 ENOG4105EJ9 Membrane AB182_06720 ENOG4108BPE -transporting atpase AB182_06725 ENOG4105MH2 YfcL protein AB182_06730 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) AB182_06735 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AB182_06745 ENOG4105CS2 ec 3.2.1.21 AB182_06750 ENOG4106WZ1 flagella biosynthesis regulator AB182_06760 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AB182_06765 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) AB182_06770 ENOG4105DQR SNARE associated Golgi AB182_06780 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase AB182_06785 ENOG4108S3P Sporulation domain protein AB182_06790 ENOG4105E96 Colicin v production protein AB182_06795 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase AB182_06800 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase AB182_06805 ENOG4105E89 ABC transporter AB182_06810 ENOG4105E89 ABC transporter AB182_06815 ENOG4105DSP amino acid AbC transporter AB182_06820 ENOG4106YG3 ABC transporter AB182_06825 ENOG4108JEH abc transporter atp-binding protein AB182_06835 ENOG4105DEI Mannitol dehydrogenase AB182_06840 ENOG4105CMG Carbohydrate kinase AB182_06845 ENOG4105IE8 Alpha-ketoglutarate permease AB182_06855 ENOG4105ECP epimerase AB182_06860 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase AB182_06865 ENOG4108SHQ Glutathione S-transferase AB182_06870 ENOG4108RE9 Phosphodiesterase AB182_06875 ENOG4105PTV Nudix Hydrolase AB182_06890 ENOG4105C6K Malic enzyme AB182_06895 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AB182_06910 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 AB182_06915 ENOG4107QWE )-transporter AB182_06925 ENOG4105CHM Aminotransferase AB182_06930 ENOG4107NQ8 LysR family Transcriptional regulator AB182_06950 ENOG4105GKE subunit e AB182_06955 ENOG4107QIZ NADH dehydrogenase AB182_06960 ENOG4107R0R NADH dehydrogenase subunit g AB182_06965 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) AB182_06975 ENOG4107UFS subunit j AB182_06985 ENOG4105D65 subunit l AB182_06990 ENOG4105C8S subunit m AB182_06995 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AB182_07000 ENOG4107R88 Chemotaxis protein (CheV) AB182_07005 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) AB182_07010 ENOG4107YB6 acetyltransferase, (GNAT) family AB182_07015 ENOG4105TNS Conserved Protein AB182_07020 ENOG4105E4F Isochorismate synthase AB182_07025 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) AB182_07030 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) AB182_07035 ENOG4108IPT Naphthoate synthase AB182_07040 ENOG4105DNI Converts SHCHC to OSB (By similarity) AB182_07045 ENOG4105CEY Amp-dependent synthetase and ligase AB182_07050 ENOG4105DNE Transposase AB182_07060 ENOG4108UII YfaZ family AB182_07070 ENOG4107258 Transcriptional regulator AB182_07080 ENOG4105CSP Major Facilitator Superfamily AB182_07090 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) AB182_07095 ENOG4108KJ0 anaerobic glycerol-3-phosphate dehydrogenase, subunit B AB182_07100 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A AB182_07105 ENOG4105CXY transporter AB182_07110 ENOG4105XPH Ferredoxin AB182_07115 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AB182_07120 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AB182_07125 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) AB182_07130 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB182_07135 ENOG4105BZU Histidine kinase AB182_07140 ENOG41068CG regulatoR AB182_07145 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC AB182_07160 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AB182_07165 ENOG4105CF1 Alkylated DNA repair protein AB182_07170 ENOG4105IBP Cyclic peptide transporter AB182_07175 ENOG4105CJW magnesium transporter AB182_07180 ENOG4105CHH sulfate transporter AB182_07185 ENOG4105DWT malate dehydrogenase (quinone) AB182_07210 ENOG4105E68 Sulfatase AB182_07215 ENOG4105PAN UPF0352 protein AB182_07235 ENOG4105CFI type iii restriction protein res subunit AB182_07240 ENOG4105I08 Pseudouridine synthase AB182_07245 ENOG4105C2C drug resistance transporter, Bcr CflA AB182_07250 ENOG4105HG6 AB182_07255 ENOG4108JQ5 ABC transporter AB182_07260 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component AB182_07265 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component AB182_07270 ENOG4105E43 Extracellular solute-binding protein, family 5 AB182_07275 ENOG4105CXC rtn protein AB182_07280 ENOG4107TT5 NLP P60 protein AB182_07285 ENOG41076MN Phosphoesterase, PA-phosphatase related AB182_07290 ENOG4105CKI cobalamin synthesis protein AB182_07295 ENOG4105DEI Mannitol dehydrogenase AB182_07300 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) AB182_07335 ENOG4105CMM transposase AB182_07360 ENOG4107TII Recombinase AB182_07365 ENOG4105KRS Proteinase inhibitor AB182_07370 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AB182_07380 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein AB182_07385 ENOG4105DE4 1-phosphofructokinase AB182_07390 ENOG4105DM4 PTS System AB182_07405 ENOG4105DD7 kinase (PfkB family AB182_07410 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) AB182_07415 ENOG4105D9N nucleoside AB182_07420 ENOG4105DD7 kinase (PfkB family AB182_07425 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) AB182_07430 ENOG4105HMI Membrane AB182_07435 ENOG4105DUM transcriptional regulator, lysR family AB182_07450 ENOG4105E5Q amino acid AbC transporter AB182_07460 ENOG4108IQI permease AB182_07465 ENOG4105D05 Receptor AB182_07475 ENOG4105CBP Major Facilitator AB182_07480 ENOG4105EUJ GTP cyclohydrolase i AB182_07485 ENOG4105DHF Membrane AB182_07490 ENOG41060NJ transcriptional regulator AB182_07500 ENOG4105C2J ABC transporter AB182_07505 ENOG4107SDZ Galactoside transport system permease protein mglC AB182_07510 ENOG4105BZP glycoside hydrolase 15-related AB182_07515 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AB182_07530 ENOG4107GZ4 SanA protein AB182_07535 ENOG4107T42 This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity) AB182_07540 ENOG41067MG lrgb family AB182_07560 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) AB182_07575 ENOG4105CS2 ec 3.2.1.21 AB182_07580 ENOG4105H9W Short-chain dehydrogenase reductase Sdr AB182_07585 ENOG4105KHU inner membrane protein YohD AB182_07590 ENOG41069YE inner membrane protein yohC AB182_07595 ENOG41061WM D-Alanyl-D-Alanine AB182_07605 ENOG4105CXG d-lactate dehydrogenase AB182_07610 ENOG4107QK4 glycoside hydrolase, family 3 domain protein AB182_07615 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system AB182_07620 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component AB182_07625 ENOG4108IJ8 ABC transporter AB182_07630 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component AB182_07635 ENOG4108XDN Transcriptional regulator AB182_07640 ENOG4108HRK Histidine kinase AB182_07645 ENOG4108NEV two component transcriptional regulator, LytTR family AB182_07650 ENOG4108W15 Protein of unknown function (DUF1456) AB182_07660 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) AB182_07665 ENOG4105D1F ATP-binding protein AB182_07675 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly AB182_07690 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase AB182_07695 ENOG4105DWF phosphomethylpyrimidine kinase AB182_07700 ENOG4105EIE fructose-bisphosphate aldolase AB182_07705 ENOG4107TE5 Lipid kinase AB182_07710 ENOG4105CFP Peptidase U32 AB182_07720 ENOG4105E3W Two component transcriptional regulator (Winged helix family AB182_07725 ENOG4105EB3 Histidine kinase AB182_07735 ENOG4105BZS acriflavin resistance protein AB182_07750 ENOG4105R8A Heat shock protein AB182_07755 ENOG4105D03 DNA-3-methyladenine glycosylase II AB182_07760 ENOG4105BZU Histidine kinase AB182_07775 ENOG4108GAE asmA family AB182_07780 ENOG4105EE5 Membrane protein terC AB182_07785 ENOG4105F2I Transposase AB182_07790 ENOG4105DAY polysaccharide export protein AB182_07795 ENOG4105KJF protein tyrosine phosphatase AB182_07800 ENOG4105D75 Capsular exopolysaccharide family AB182_07805 ENOG41090RK glycosyl transferase AB182_07810 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB AB182_07815 ENOG4107RXY Glycosyl transferase AB182_07820 ENOG4108NYJ Colanic acid AB182_07825 ENOG4105ECJ Glycosyl Transferase AB182_07830 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF AB182_07835 ENOG4105C0K Gdp-mannose 4,6-dehydratase AB182_07840 ENOG4105C30 Nad-dependent epimerase dehydratase AB182_07845 ENOG4105FGF GDP-mannose mannosyl hydrolase AB182_07850 ENOG4106CD9 glycosyl transferase group 1 AB182_07855 ENOG4105CJT Mannose-1-phosphate guanylyltransferase AB182_07860 ENOG4107QKV phosphomannomutase AB182_07865 ENOG4105D3Q Sugar transferase AB182_07870 ENOG4105PSV Polysaccharide Biosynthesis Protein AB182_07875 ENOG4105C74 pyruvyl transferase AB182_07880 ENOG4107T8Q Glycosyl transferase (Group 1 AB182_07885 ENOG4105G1A colanic acid biosynthesis protein AB182_07890 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AB182_07905 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase AB182_07910 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase AB182_07915 ENOG4108RT7 Glycosyl transferase, family 2 AB182_07925 ENOG4105EY8 ABC transporter AB182_07930 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AB182_07935 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) AB182_07955 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) AB182_07970 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase AB182_07980 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase AB182_07985 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) AB182_08000 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) AB182_08005 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) AB182_08010 ENOG4108535 NAD dependent epimerase/dehydratase family AB182_08015 ENOG4105CUB amino acid AB182_08020 ENOG4105CJB Exodeoxyribonuclease I AB182_08025 ENOG4105DZ1 carboxypeptidase AB182_08030 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) AB182_08035 ENOG4105DR8 Membrane AB182_08040 ENOG41090HJ UPF0265 protein AB182_08045 ENOG4105JZC GHMP kinase AB182_08050 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AB182_08055 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AB182_08060 ENOG4105KTW ethanolamine utilization protein AB182_08065 ENOG4105M3W utilization protein AB182_08075 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) AB182_08085 ENOG4108EKI Dehydrogenase AB182_08095 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml AB182_08105 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) AB182_08115 ENOG4105KNY Microcompartments protein AB182_08125 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit AB182_08130 ENOG4108ZFT Dehydratase small subunit AB182_08135 ENOG4105YCI dehydratase medium subunit AB182_08140 ENOG4105DMB glycerol dehydratase AB182_08145 ENOG4105EHR propanediol utilization protein pduB AB182_08150 ENOG4105KNY Microcompartments protein AB182_08155 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) AB182_08160 ENOG4107XVH Transcriptional regulator AB182_08165 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) AB182_08170 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) AB182_08175 ENOG41081F0 Precorrin-8x methylmutase AB182_08180 ENOG4105EE8 May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity) AB182_08185 ENOG4108DR9 Cobalt-precorrin-6Y C(5)-methyltransferase AB182_08190 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase AB182_08195 ENOG4105CIA precorrin-4 C(11)-methyltransferase AB182_08200 ENOG4108P62 biosynthesis protein (CbiG) AB182_08205 ENOG4105E4R Precorrin-3B C17-methyltransferase AB182_08210 ENOG4105QUC reductase AB182_08215 ENOG4107PPM cobalt chelatase AB182_08220 ENOG4105DVK Precorrin-2 c20-methyltransferase AB182_08225 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) AB182_08230 ENOG4105W4R Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) AB182_08235 ENOG4108V4M Cobalt abc transporter AB182_08245 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) AB182_08250 ENOG4108YZT Adenosylcobinamide kinase AB182_08265 ENOG4105YVS arsR family transcriptional regulator AB182_08270 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) AB182_08285 ENOG4107NQ8 LysR family Transcriptional regulator AB182_08290 ENOG4108M8W Monooxygenase AB182_08315 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB182_08320 ENOG4105F04 LysR family Transcriptional regulator AB182_08335 ENOG4105UQX Mate efflux family protein AB182_08345 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component AB182_08355 ENOG4105EG2 ABC transporter, permease AB182_08365 ENOG4105CHR reductase AB182_08370 ENOG4105E98 transcriptional regulator DeoR family AB182_08375 ENOG4106P19 photosystem i assembly btpa AB182_08380 ENOG4105CMG Carbohydrate kinase AB182_08390 ENOG4105E98 transcriptional regulator DeoR family AB182_08400 ENOG4105DC7 peptidase M24 AB182_08405 ENOG4105FYV Amp nucleosidase AB182_08410 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family AB182_08415 ENOG4108WUH Transcriptional regulator, TetR family AB182_08420 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AB182_08590 ENOG4107R11 Transcriptional regulator AB182_08610 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) AB182_08650 ENOG41087BU transcriptional repressor DicA AB182_08690 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) AB182_08705 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) AB182_08715 ENOG4105QBX endodeoxyribonuclease RusA AB182_08720 ENOG4108MXB Protein of unknown function (DUF968) AB182_08735 ENOG4105QFS Lysis protein S homolog from lambdoid prophage AB182_08790 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AB182_08880 ENOG4105ZIT Porin Gram-negative type AB182_08890 ENOG4105EST Metal Dependent Phosphohydrolase AB182_08895 ENOG41090BB DNA mismatch endonuclease (vsr) AB182_08900 ENOG4105FDR Membrane AB182_08905 ENOG4105CKW Inner membrane protein yedI AB182_08910 ENOG4105VNZ cytoplasmic protein AB182_08925 ENOG4105YX3 cellular response to acidity AB182_08935 ENOG4107TKS colanic acid capsular biosynthesis activation protein A AB182_08940 ENOG4105D19 Role in flagellar biosynthesis (By similarity) AB182_08945 ENOG4105VS8 Flagellar biosynthetic protein fliq AB182_08950 ENOG4105CN7 Flagellar biosynthetic protein FliP AB182_08955 ENOG4105K0P flagellar biosynthesis protein AB182_08960 ENOG4105DD5 Flagellar motor switch protein AB182_08965 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AB182_08970 ENOG4107ZI8 flagellar basal body-associated protein flil AB182_08975 ENOG4105WF4 Flagellar hook-length control protein AB182_08980 ENOG4105GSA Flagellar export protein flij AB182_08985 ENOG4108JIR Flagellum-specific ATP synthase AB182_08990 ENOG41090PJ Flagellar assembly protein AB182_08995 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AB182_09000 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) AB182_09005 ENOG4105VQ0 flagellar hook-basal body complex protein fliE AB182_09010 ENOG4108RS6 transposase AB182_09015 ENOG4105KSU Redox protein AB182_09020 ENOG41066VF YeeE YedE family protein AB182_09025 ENOG4105JCU Inherit from NOG: (Lipo)protein AB182_09030 ENOG4105E5K Alpha-amylase AB182_09035 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) AB182_09040 ENOG4105MQ3 flagellar protein FliS AB182_09045 ENOG4105DTS flagellar hook-associated AB182_09060 ENOG4105E5H Transposase AB182_09065 ENOG4108YXQ IS66 Orf2 family protein AB182_09090 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AB182_09095 ENOG4108M9K flagella biosynthesis protein FliZ AB182_09100 ENOG4105EAB amino acid AbC transporter AB182_09110 ENOG4105E5Q amino acid AbC transporter AB182_09115 ENOG4105CDA abc transporter atp-binding protein AB182_09120 ENOG4105VJY transcriptional regulator AB182_09125 ENOG4105XVG cytoplasmic protein AB182_09130 ENOG4105WH1 Two component transcriptional regulator luxr family AB182_09135 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) AB182_09140 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase AB182_09165 ENOG4105CMM transposase AB182_09175 ENOG4108P8R AB182_09180 ENOG4108MXD gtp-binding protein AB182_09200 ENOG4106ZN7 UPF0401 protein YkfF AB182_09210 ENOG4105MFG Antirestriction protein AB182_09220 ENOG4108XS9 dna repair protein AB182_09225 ENOG4105ZS6 Protein of unknown function (DUF987) AB182_09230 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles AB182_09235 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures AB182_09265 ENOG4107SSZ Phosphatase AB182_09270 ENOG4107XHZ cytoplasmic chaperone TorD family protein AB182_09275 ENOG4108UQ5 membrane protein YcdZ AB182_09280 ENOG4105P8Q Curli production assembly transport component CsgG AB182_09285 ENOG4108WYR Curli production assembly transport component, CsgF AB182_09290 ENOG4108XDW curli assembly protein CsgE AB182_09295 ENOG41086KC Transcriptional regulator AB182_09300 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers AB182_09320 ENOG4108UVJ appr-1-p processing domain protein AB182_09325 ENOG4107RZC phospholipase d AB182_09330 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) AB182_09340 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) AB182_09345 ENOG4105NAC (LipO)protein AB182_09350 ENOG4108W47 Acidic protein msyB AB182_09355 ENOG4105C6X Major Facilitator AB182_09360 ENOG4105D1S lipid A biosynthesis AB182_09370 ENOG4108YYC ycei family AB182_09375 ENOG4105DS1 cytochrome b561 AB182_09380 ENOG4105F76 Sarcosine oxidase AB182_09385 ENOG4105PVA Biofilm formation regulatory protein BssS AB182_09390 ENOG4105MEA DNA damage-inducible protein i AB182_09395 ENOG4105EKE dihydroorotase AB182_09400 ENOG4105F3T (LipO)protein AB182_09405 ENOG4105E9S glutaredoxin 2 AB182_09415 ENOG4105D9U N-acetyltransferase AB182_09420 ENOG4108YXG UPF0502 protein AB182_09425 ENOG4105EP9 oxidoreductase AB182_09430 ENOG4105CJR Integral membrane protein (MviN AB182_09435 ENOG4105QVD Flagella synthesis protein FlgN AB182_09440 ENOG4105M9M anti-sigma28 factor FlgM AB182_09445 ENOG4105CKS Flagella basal body P-ring formation protein flgA AB182_09450 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) AB182_09455 ENOG4108ZC9 flagellar basal-body rod protein flgc AB182_09460 ENOG4105W00 Flagellar hook capping protein AB182_09465 ENOG4105BZE flagellar hook protein, FlgE AB182_09470 ENOG4108KPB Flagellar basal-body rod protein FlgF AB182_09475 ENOG4105CGA flagellar basal-body rod protein FlgG AB182_09490 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj AB182_09495 ENOG4105E1Q flagellar hook-associated protein AB182_09500 ENOG4105DTJ flagellar hook-associated protein AB182_09505 ENOG4105EQ0 Major Facilitator superfamily AB182_09510 ENOG4105EJC lysr family transcriptional regulator AB182_09515 ENOG4107QQB Ribonuclease E AB182_09520 ENOG4105EI2 Pseudouridine synthase AB182_09530 ENOG4108UHJ MAF-like protein AB182_09535 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein AB182_09540 ENOG4105VGS 50s ribosomal protein l32 AB182_09545 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) AB182_09550 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AB182_09555 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AB182_09560 ENOG4105CHR reductase AB182_09565 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) AB182_09570 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AB182_09575 ENOG4105YAZ 4-amino-4-deoxychorismate lyase AB182_09580 ENOG4105HHA aminodeoxychorismate lyase AB182_09585 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) AB182_09590 ENOG4107QRG dna polymerase iii AB182_09595 ENOG4105F8V Hydrolase, tatD family AB182_09600 ENOG4105CI1 PTS System AB182_09605 ENOG4105CNM Receptor AB182_09610 ENOG4105K59 histidine triad (HIT) protein AB182_09615 ENOG41090DQ Lipoprotein AB182_09620 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) AB182_09640 ENOG4105CEP NADH dehydrogenase AB182_09645 ENOG4107MBR 17 kDa surface antigen AB182_09650 ENOG4108IND Tetr family transcriptional regulator AB182_09655 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction AB182_09660 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AB182_09665 ENOG4108JA2 transcriptioN-repair coupling factor AB182_09670 ENOG4105EQR Transposase IS116 IS110 IS902 AB182_09675 ENOG4105IQC Inner membrane protein YcfT AB182_09680 ENOG4105D60 lipoprotein releasing system transmembrane protein AB182_09690 ENOG4105D60 lipoprotein releasing system transmembrane protein AB182_09695 ENOG4105EZX Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity) AB182_09700 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) AB182_09705 ENOG4107RUE extracellular solute-binding protein family 1 AB182_09715 ENOG4105F38 ABC transporter, permease AB182_09730 ENOG4105EZE Cupin 4 family protein AB182_09735 ENOG4105IFJ Histidine kinase AB182_09740 ENOG4105XJC Two component transcriptional regulator (Winged helix family AB182_09745 ENOG4107QTF adenylosuccinate lyase AB182_09755 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) AB182_09760 ENOG4105C8Q Methyl-accepting chemotaxis AB182_09775 ENOG4108R99 pseudouridine synthase AB182_09780 ENOG4108HMX isocitrate dehydrogenase (NADP) AB182_09805 ENOG4108PNB DNA-binding transcriptional regulator AB182_09825 ENOG410620I Diguanylate cyclase AB182_09835 ENOG4105K78 MarR family Transcriptional regulator AB182_09845 ENOG4105DJ2 Major Facilitator Superfamily AB182_09850 ENOG4105R1U AraC Family Transcriptional Regulator AB182_09855 ENOG4105CT1 (ABC) transporter AB182_09865 ENOG4105E5Q amino acid AbC transporter AB182_09870 ENOG4105DRP amino acid AbC transporter AB182_09875 ENOG4108VMM UPF0756 membrane protein AB182_09885 ENOG4105CT4 transporter AB182_09890 ENOG4108KXH Ybak prolyl-tRNA synthetase associated AB182_09895 ENOG4106AKX UPF0229 protein AB182_09900 ENOG4105CYN Serine protein kinase AB182_09905 ENOG4105GNX MltA-interacting MipA family protein AB182_09910 ENOG4105CV8 reductase AB182_09915 ENOG4105DSB aldose 1-epimerase AB182_09920 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AB182_09930 ENOG4105VUT cytoplasmic protein AB182_09935 ENOG4105CPQ Dehydrogenase AB182_09940 ENOG4107TE1 transport protein AB182_09945 ENOG4105CPQ Dehydrogenase AB182_09950 ENOG4105D2N Aldolase AB182_09955 ENOG4107UH8 sugar kinase AB182_09960 ENOG4105CPC Aldo Keto reductase AB182_09965 ENOG4105E98 transcriptional regulator DeoR family AB182_09970 ENOG4108KUU Inner membrane metabolite transport protein ydjE AB182_09975 ENOG4108RWI nicotinamidase AB182_09980 ENOG4105HDK L-asparaginase AB182_09985 ENOG4105D07 Signal peptide peptidase, SppA AB182_09990 ENOG41069NU Nitroreductase AB182_09995 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) AB182_10000 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AB182_10005 ENOG4105D82 Glutamate dehydrogenase AB182_10010 ENOG4105MTM Protein of unknown function (DUF1496) AB182_10015 ENOG4105M6F mutator MutT protein AB182_10020 ENOG4107RM6 sulfurtransferase AB182_10025 ENOG4105CGK Exodeoxyribonuclease III AB182_10035 ENOG4105CI2 imidazolone-5-propionate hydrolase AB182_10040 ENOG4105CZE histidine utilization repressor AB182_10045 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) AB182_10060 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AB182_10070 ENOG4105C84 Histidine ammonia-lyase AB182_10075 ENOG4105CGP Urocanate hydratase AB182_10080 ENOG4105E45 Histidinol-phosphate aminotransferase AB182_10100 ENOG4105F4X arginine AB182_10105 ENOG4105C26 Dehydrogenase AB182_10110 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) AB182_10115 ENOG4107UI5 Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity) AB182_10130 ENOG4108SPG Periplasmic Protein AB182_10135 ENOG41090B9 response to stress AB182_10140 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) AB182_10145 ENOG4107RA1 nh(3)-dependent nad( ) synthetase AB182_10150 ENOG4105KKI DNA-binding transcriptional activator OsmE AB182_10155 ENOG4105VZJ PTS System AB182_10160 ENOG4105CK1 PTS System AB182_10165 ENOG4105VCP PTS System AB182_10170 ENOG4105EZV Transcriptional regulator AB182_10175 ENOG4105F8D glycoside hydrolase family 4 AB182_10180 ENOG410901P UPF0249 protein AB182_10185 ENOG4105CH6 catalase AB182_10190 ENOG4105R8J Activates the cell division inhibited by chromosomal DNA over-replication (By similarity) AB182_10195 ENOG4108ETY sodium dicarboxylate symporter AB182_10200 ENOG4107K5X Membrane-bound metal-dependent hydrolase AB182_10205 ENOG4105CHR reductase AB182_10210 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 AB182_10215 ENOG4107PN8 YfeABCD locus regulator AB182_10220 ENOG4105FGM Fructosamine kinase AB182_10225 ENOG4105P10 Uncharacterized protein ydiZ AB182_10230 ENOG4105DE4 1-phosphofructokinase AB182_10235 ENOG4108NE3 Salt-induced outer membrane protein AB182_10245 ENOG4105RFR Protein of unknown function (DUF2767) AB182_10255 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) AB182_10260 ENOG41082NX 50s ribosomal protein l35 AB182_10265 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) AB182_10270 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) AB182_10275 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) AB182_10280 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) AB182_10290 ENOG4108V06 Glutathione peroxidase AB182_10300 ENOG4108QBX (LipO)protein AB182_10315 ENOG4106EDX Hemin uptake protein AB182_10320 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AB182_10330 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) AB182_10345 ENOG4105IPI Membrane AB182_10350 ENOG4105CQB FAD linked oxidase domain protein AB182_10355 ENOG4105KA0 thioesterase Superfamily protein AB182_10360 ENOG4105D1S lipid A biosynthesis AB182_10370 ENOG4108MEK Metal-binding protein YodA AB182_10385 ENOG4108Z4V iron-sulfur cluster assembly AB182_10390 ENOG4105DIW FeS assembly protein SUFB AB182_10395 ENOG4105C3K feS assembly ATPase SufC AB182_10400 ENOG4105JRK feS assembly protein SufD AB182_10405 ENOG4105C9B Cysteine desulfurase AB182_10410 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) AB182_10415 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AB182_10425 ENOG4105CA9 Pyruvate kinase AB182_10430 ENOG4107TK4 histidinol-phosphate phosphatase AB182_10435 ENOG4105DQ4 alcohol dehydrogenase AB182_10470 ENOG4108R6K riboflavin synthase, subunit alpha AB182_10475 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AB182_10480 ENOG4105CZQ inner membrane transport protein YdhC AB182_10485 ENOG4105F52 Transcriptional regulator AB182_10495 ENOG4105F27 Major Facilitator AB182_10500 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AB182_10505 ENOG4105K4H Nlp p60 protein AB182_10510 ENOG4105M2J Glutaredoxin AB182_10515 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) AB182_10520 ENOG4108UYE Lactoylglutathione lyase AB182_10525 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB182_10530 ENOG4108WUH Transcriptional regulator, TetR family AB182_10535 ENOG4105XZD Fe-S protein AB182_10540 ENOG4107RGM aldo keto reductase AB182_10545 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AB182_10550 ENOG4105DSW Fusaric acid resistance protein AB182_10555 ENOG4105Y49 secretion protein, HlyD family AB182_10570 ENOG4108XTF Outer Membrane Lipoprotein AB182_10575 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) AB182_10580 ENOG410642K Lysozyme inhibitor AB182_10585 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) AB182_10590 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) AB182_10595 ENOG4108K3A Glutathione S-transferase AB182_10600 ENOG4105DUX Transporter AB182_10610 ENOG4105CSM endonuclease III AB182_10620 ENOG4108UQQ Electron transport complex AB182_10625 ENOG4105D6A Electron transport complex AB182_10640 ENOG4105DGN Electron transport complex AB182_10645 ENOG4105M9B inner membrane protein ydgK AB182_10650 ENOG4105QZ5 OriC-binding nucleoid-associated protein AB182_10655 ENOG4106C6R beta-lactam resistance protein AB182_10660 ENOG4105D9R oxidoreductase AB182_10665 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) AB182_10670 ENOG4108RW8 Universal stress protein F AB182_10675 ENOG4105F2I Transposase AB182_10685 ENOG4106J39 exported protein AB182_10690 ENOG4105EIP mannose-6-phosphate isomerase AB182_10695 ENOG4107GFK fumarate AB182_10700 ENOG4105C9Q fumarate hydratase class II AB182_10710 ENOG4105JJR Histidine kinase AB182_10715 ENOG4107EXC regulatoR AB182_10720 ENOG4105RA2 Membrane AB182_10725 ENOG410642E Short chain dehydrogenase AB182_10730 ENOG4105D5Q Arginine ornithine antiporter AB182_10735 ENOG4105C5D exported protein AB182_10745 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AB182_10750 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AB182_10755 ENOG4105D64 Mechanosensitive ion channel AB182_10765 ENOG4105C5Q Transcriptional regulator AB182_10770 ENOG4105Q9Y Universal stress protein AB182_10775 ENOG4105DS0 Transcriptional regulator, Crp Fnr family AB182_10780 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AB182_10785 ENOG4108DG9 Smr protein MutS2 AB182_10790 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AB182_10795 ENOG4105C8Q Methyl-accepting chemotaxis AB182_10800 ENOG4107RSM transcriptional regulator AB182_10805 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase AB182_10815 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) AB182_10830 ENOG4108ZSJ is1 orf2 AB182_10840 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB182_10845 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein AB182_10850 ENOG4108MG3 formate dehydrogenase AB182_10860 ENOG4105GR3 Histidine kinase AB182_10865 ENOG4105E3W Two component transcriptional regulator (Winged helix family AB182_10870 ENOG4105F2I Transposase AB182_10880 ENOG4105BZS acriflavin resistance protein AB182_10910 ENOG4105ETT transcriptional Regulator, LysR family AB182_10915 ENOG4105D3G Pseudouridine synthase AB182_10920 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme AB182_10935 ENOG4105C8Q Methyl-accepting chemotaxis AB182_10950 ENOG4105N0E Protein of unknown function (DUF2543) AB182_10980 ENOG4105ETP RND efflux system, outer membrane lipoprotein AB182_10985 ENOG4108MI0 Resistance protein AB182_10990 ENOG4105J12 Multidrug resistance protein mdtN AB182_11030 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) AB182_11035 ENOG4105F0Z galactose-1-phosphate uridylyltransferase AB182_11045 ENOG4107FKK extracellular solute-binding protein family 1 AB182_11055 ENOG4105EG2 ABC transporter, permease AB182_11065 ENOG4105C4C beta-galactosidase AB182_11070 ENOG4105CI1 PTS System AB182_11075 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) AB182_11080 ENOG4105ETE Transcriptional regulator (LacI family AB182_11090 ENOG4107RQD Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity) AB182_11105 ENOG4105EMU Dehydrogenase AB182_11110 ENOG4105EQ2 LysR family Transcriptional regulator AB182_11130 ENOG4105HEI LysR family (Transcriptional regulator AB182_11140 ENOG41080BE Methyl-accepting chemotaxis sensory transducer AB182_11140 ENOG41080BE Methyl-accepting chemotaxis sensory transducer AB182_11150 ENOG4105DZC cytosine deaminase AB182_11160 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin AB182_11165 ENOG4108V06 Glutathione peroxidase AB182_11170 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase AB182_11175 ENOG4105NAE bifunctional deaminase-reductase domain protein AB182_11220 ENOG41090RK glycosyl transferase AB182_11230 ENOG4108MES Periplasmic binding protein AB182_11235 ENOG4105DQ5 transport system permease protein AB182_11240 ENOG4108IHU transport system permease protein AB182_11245 ENOG4105E0A ABC, transporter AB182_11260 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) AB182_11265 ENOG4105GQR Chaperone AB182_11280 ENOG4105F4G Membrane AB182_11285 ENOG41090TI Catalyzes the excretion of spermidine (By similarity) AB182_11290 ENOG4108ZBZ Catalyzes the excretion of spermidine (By similarity) AB182_11300 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap AB182_11310 ENOG4108ZBR Gcn5-related n-acetyltransferase AB182_11315 ENOG4105CTD carboxy-peptidase AB182_11320 ENOG4105D94 Major Facilitator Superfamily AB182_11325 ENOG4106NZI LysR family Transcriptional regulator AB182_11330 ENOG4105DAG ROK family AB182_11335 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) AB182_11340 ENOG4108IJ8 ABC transporter AB182_11345 ENOG4105E90 ABC transporter AB182_11350 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system AB182_11355 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component AB182_11360 ENOG4108NEM leader-binding protein dmsD AB182_11365 ENOG4107KGK dmso reductase anchor subunit AB182_11370 ENOG4105QAX Iron-sulfur AB182_11375 ENOG4107QY8 reductase AB182_11380 ENOG4105KBG Protein of unknown function (DUF1161) AB182_11390 ENOG4108MK9 spermidine N(1)-acetyltransferase AB182_11400 ENOG4105KK4 UPF0060 membrane protein AB182_11405 ENOG4105CXK mandelate racemase muconate lactonizing AB182_11415 ENOG4105DEI Mannitol dehydrogenase AB182_11420 ENOG41061EV selenium-binding protein YdfZ AB182_11425 ENOG4107XBN GntR Family Transcriptional Regulator AB182_11430 ENOG4105EMU Dehydrogenase AB182_11435 ENOG4105DGW oligopeptidase A AB182_11450 ENOG4105CMQ Chloride channel AB182_11475 ENOG4108URH decarboxylase AB182_11490 ENOG4105Y49 secretion protein, HlyD family AB182_11500 ENOG4105DSW Fusaric acid resistance protein AB182_11505 ENOG4105R1U AraC Family Transcriptional Regulator AB182_11520 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AB182_11525 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AB182_11530 ENOG4105VEQ Cold shock protein AB182_11540 ENOG4105E7U AraC family transcriptional regulator AB182_11545 ENOG4105ECQ AraC Family Transcriptional Regulator AB182_11550 ENOG4108SUT Major Facilitator Superfamily AB182_11555 ENOG4108VHC Short-chain dehydrogenase reductase Sdr AB182_11560 ENOG4105EMU Dehydrogenase AB182_11565 ENOG4105T95 Thiol disulfide interChange protein AB182_11570 ENOG4105CHR reductase AB182_11575 ENOG4105KVH Transcriptional regulator AB182_11615 ENOG4105E5W Transporter AB182_11620 ENOG4108594 Permease of the drug metabolite transporter AB182_11625 ENOG4106DNR multiple antibiotic resistance protein AB182_11635 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes AB182_11645 ENOG4105F27 Major Facilitator AB182_11650 ENOG4105JAB phenazine biosynthesis protein, phzf family AB182_11655 ENOG4105CHR reductase AB182_11675 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB182_11680 ENOG4105C0A alcohol dehydrogenase AB182_11685 ENOG4107S2N Type III effector Hrp-dependent AB182_11690 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) AB182_11695 ENOG4105MVE transcriptional regulator AB182_11710 ENOG4105EGI Transcriptional regulator AB182_11715 ENOG4105C26 Dehydrogenase AB182_11720 ENOG4105C8Q Methyl-accepting chemotaxis AB182_11725 ENOG4105CSV Glutaminase AB182_11730 ENOG4105M0C cytoplasmic protein AB182_11735 ENOG4105BZU Histidine kinase AB182_11740 ENOG4105BZU Histidine kinase AB182_11745 ENOG4105BZU Histidine kinase AB182_11750 ENOG4107QZW Altronate oxidoreductase AB182_11760 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) AB182_11800 ENOG4105C8Q Methyl-accepting chemotaxis AB182_11805 ENOG4105D58 Diguanylate phosphodiesterase AB182_11820 ENOG4108JUA Transcriptional regulator AB182_11825 ENOG4105DS4 PAS PAC sensor Signal transduction histidine kinase AB182_11915 ENOG4105CSH Transporter AB182_11935 ENOG4105T38 integral membrane protein AB182_11940 ENOG4107SQD Transcriptional regulator, GntR family AB182_11950 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein AB182_11965 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) AB182_11970 ENOG4105CZE histidine utilization repressor AB182_11985 ENOG4107VIJ nudix hydrolase AB182_11990 ENOG4105E98 transcriptional regulator DeoR family AB182_11995 ENOG4108VKM cytochrome b561 AB182_12000 ENOG41080HT Transcriptional regulator, arsr family AB182_12015 ENOG4105DTD Dehydrogenase AB182_12020 ENOG4105CY2 Citrate transporter AB182_12025 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) AB182_12030 ENOG4105CHU acetyl-coa acetyltransferase AB182_12040 ENOG4105D6N CoA-transferase, subunit a AB182_12045 ENOG4105DUM transcriptional regulator, lysR family AB182_12060 ENOG4105F32 YngK protein AB182_12065 ENOG4105DHT Metal Dependent Phosphohydrolase AB182_12070 ENOG4105CFH Aspartokinase AB182_12075 ENOG4108JPW Aminotransferase AB182_12080 ENOG4105DY8 decarboxylase AB182_12090 ENOG4105DJB Major Facilitator Superfamily AB182_12100 ENOG4105C5I Dehydrogenase AB182_12105 ENOG41061TZ Short-chain dehydrogenase reductase Sdr AB182_12130 ENOG4105DQ5 transport system permease protein AB182_12135 ENOG4105E0A ABC, transporter AB182_12180 ENOG4105CDA abc transporter atp-binding protein AB182_12185 ENOG4105E5Q amino acid AbC transporter AB182_12190 ENOG4105E5Q amino acid AbC transporter AB182_12195 ENOG4105EAB amino acid AbC transporter AB182_12200 ENOG4105RHY Pfam:UPF0157 AB182_12215 ENOG41075H3 AraC family transcriptional regulator AB182_12240 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB182_12270 ENOG4105BZU Histidine kinase AB182_12275 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AB182_12280 ENOG4105FN4 Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond (By similarity) AB182_12290 ENOG4107R1I NAD-dependent malic enzyme AB182_12295 ENOG4105CFQ glutamine synthetase AB182_12300 ENOG4105C5H ABC transporter AB182_12310 ENOG4105F27 Major Facilitator AB182_12320 ENOG4108MG3 formate dehydrogenase AB182_12325 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein AB182_12330 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB182_12335 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB182_12340 ENOG4105RPH Inner membrane protein YddG AB182_12365 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase AB182_12370 ENOG4107RCV ABC transporter, permease AB182_12375 ENOG4105C4Y ABC transporter AB182_12380 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AB182_12385 ENOG4105BZU Histidine kinase AB182_12390 ENOG4105DG4 malate L-lactate dehydrogenase AB182_12395 ENOG4108MEJ flavin reductase domain protein AB182_12405 ENOG4108N27 Glutathione S-transferase AB182_12415 ENOG4105ETE Transcriptional regulator (LacI family AB182_12420 ENOG4105DIA mandelate racemase muconate lactonizing AB182_12425 ENOG4105DJB Major Facilitator Superfamily AB182_12430 ENOG4105CDA abc transporter atp-binding protein AB182_12435 ENOG4105E5Q amino acid AbC transporter AB182_12445 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) AB182_12455 ENOG4105CH2 amidohydrolase AB182_12460 ENOG4105DEN Luciferase family AB182_12465 ENOG4105C85 amino acid AB182_12470 ENOG4108NS2 receptor AB182_12475 ENOG4105CHB tonB-dependent Receptor AB182_12480 ENOG4105C8Q Methyl-accepting chemotaxis AB182_12485 ENOG4108WYP Transcriptional regulator AB182_12490 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein AB182_12500 ENOG4108Z7F N-acetyltransferase AB182_12505 ENOG4108T9Y Inner membrane protein ydcZ AB182_12510 ENOG4105R71 cytoplasmic protein AB182_12515 ENOG4105DEF Extracellular solute-binding protein, family 5 AB182_12555 ENOG4105C26 Dehydrogenase AB182_12560 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component AB182_12565 ENOG4105D81 ABC transporter, permease AB182_12570 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AB182_12575 ENOG4107TYH extracellular solute-binding protein family 1 AB182_12580 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB182_12585 ENOG4105C4M (Ubiquinol oxidase) subunit I AB182_12590 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AB182_12595 ENOG4105C8Q Methyl-accepting chemotaxis AB182_12605 ENOG4105CFP Peptidase U32 AB182_12610 ENOG4108JCI Transcriptional regulator AB182_12615 ENOG4105DKK Benzoate AB182_12620 ENOG4105W4W Transcriptional regulator AB182_12630 ENOG4108RS6 transposase AB182_12635 ENOG4108KKZ (LipO)protein AB182_12640 ENOG4105DEF Extracellular solute-binding protein, family 5 AB182_12645 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) AB182_12650 ENOG41088CC tellurite resistance protein tehB AB182_12655 ENOG4107WE3 acetyltransferase YdcK AB182_12660 ENOG4108Z9I -acetyltransferase AB182_12665 ENOG4105DJ9 glucan biosynthesis protein AB182_12670 ENOG4105E89 ABC transporter AB182_12675 ENOG4105CHM Aminotransferase AB182_12685 ENOG4105EBR Carboxylesterase AB182_12690 ENOG4105E32 cytoplasmic protein AB182_12695 ENOG4105DDW LysR family Transcriptional regulator AB182_12700 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit AB182_12710 ENOG4108RS6 transposase AB182_12715 ENOG4105C8Q Methyl-accepting chemotaxis AB182_12730 ENOG4105C8Q Methyl-accepting chemotaxis AB182_12735 ENOG4105KT7 mgtC SapB transporter AB182_12745 ENOG4105CSH Transporter AB182_12750 ENOG4105CPW cytochrome b561 AB182_12755 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AB182_12770 ENOG4105C26 Dehydrogenase AB182_12775 ENOG4107DB1 DUF218 domain AB182_12795 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AB182_12805 ENOG4108KQ5 Integrase catalytic subunit AB182_12810 ENOG4105CQ7 ATP-dependent helicase AB182_12815 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) AB182_12820 ENOG410689M (LipO)protein AB182_12825 ENOG4107H52 Dicarboxylate transport AB182_12830 ENOG4105C5I Dehydrogenase AB182_12835 ENOG41090X5 Heat shock protein hslJ AB182_12845 ENOG4108ZNX Heat shock protein AB182_12850 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) AB182_12885 ENOG4107R08 Integrase AB182_12890 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) AB182_12895 ENOG4108RS6 transposase AB182_12915 ENOG4105BZU Histidine kinase AB182_12920 ENOG410671Z uncharacterized protein ydiH AB182_12925 ENOG4107QSI ABC, transporter AB182_12930 ENOG4105KXI murein peptide amidase A AB182_12935 ENOG4107S8C mandelate racemase muconate lactonizing AB182_12940 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) AB182_12945 ENOG4108JU8 Transcriptional regulator AB182_12950 ENOG4106K28 UPF0283 membrane protein AB182_12955 ENOG4105CM6 amino acid regulated cytosolic protein AB182_12960 ENOG4105K8Z Phage shock protein AB182_12965 ENOG4105NNG Peripheral inner membrane phage-shock protein AB182_12970 ENOG4105FM1 phage shock protein C AB182_12975 ENOG4105YYT phage shock protein B AB182_12980 ENOG41087YS Phage shock protein A AB182_12985 ENOG4105E51 psp operon transcriptional activator AB182_12990 ENOG4108J59 Extracellular solute-binding protein, family 5 AB182_12995 ENOG4108I5W peptide transport system, permease protein AB182_13000 ENOG4108EU3 peptide transport system, permease AB182_13005 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein AB182_13010 ENOG4108JQ2 peptide transport system atp-binding protein AB182_13015 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH AB182_13020 ENOG4105Q4T oxidoreductase AB182_13030 ENOG4105BZU Histidine kinase AB182_13035 ENOG4105E39 Enoyl-CoA hydratase AB182_13040 ENOG410643D UPF0509 protein AB182_13045 ENOG4105N2W Transcriptional regulator AB182_13050 ENOG41061RM osmotically inducible lipoprotein AB182_13055 ENOG4108ZJT translation initiation factor, Sui1 AB182_13060 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) AB182_13065 ENOG4105CFV Tetratricopeptide repeat protein AB182_13070 ENOG4105Q4A inner membrane protein yciS AB182_13075 ENOG4105EYK Phosphatidylglycerophosphatase B AB182_13080 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) AB182_13085 ENOG4107QM5 aconitate hydratase AB182_13090 ENOG4107R11 Transcriptional regulator AB182_13095 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AB182_13100 ENOG4105RKX Protein of unknown function (DUF2498) AB182_13105 ENOG4105ERU peptidase AB182_13110 ENOG4105UBK short-chain dehydrogenase reductase AB182_13115 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase AB182_13120 ENOG4105FE9 pseudouridine synthase AB182_13165 ENOG4107RTD sua5 ycio yrdc ywlc family protein AB182_13170 ENOG4105DB7 PHP domain protein AB182_13175 ENOG4105CRQ synthase (Component I) AB182_13180 ENOG4108EFP Anthranilate synthase component II AB182_13185 ENOG4105DK0 Indole-3-glycerol phosphate synthase AB182_13190 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) AB182_13195 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) AB182_13215 ENOG4105EIF outer membrane protein W AB182_13220 ENOG4105PI0 Ferredoxin AB182_13225 ENOG4108S3I UPF0259 membrane protein AB182_13235 ENOG4105NAU thioesterase Superfamily protein AB182_13240 ENOG410822N TonB family AB182_13245 ENOG4105K9H YciI-like protein AB182_13255 ENOG410829K Lysine exporter protein (Lyse ygga) AB182_13265 ENOG4108W5H UPF0263 protein AB182_13270 ENOG4108JQ7 (ABC) transporter AB182_13275 ENOG4105C3U ABC transporter AB182_13280 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB182_13285 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AB182_13290 ENOG4107QSI ABC, transporter AB182_13295 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein AB182_13300 ENOG4108EKI Dehydrogenase AB182_13305 ENOG4107104 thymidine kinase AB182_13315 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AB182_13320 ENOG4105I93 response regulator AB182_13325 ENOG4105D78 K07001 NTE family protein AB182_13335 ENOG4105CIY formyltetrahydrofolate deformylase AB182_13360 ENOG41076YT nitrate reductase, gamma subunit AB182_13365 ENOG4105R3A Nitrate reductase AB182_13370 ENOG4108IUE nitrate reductase beta subunit AB182_13375 ENOG4105CRU nitrate reductase, alpha subunit AB182_13380 ENOG4105DQQ Major facilitator superfamily MFS_1 AB182_13385 ENOG4105BZU Histidine kinase AB182_13390 ENOG4105WH1 Two component transcriptional regulator luxr family AB182_13395 ENOG4105ID0 Putative invasin AB182_13410 ENOG4107QZF nitrite reductase NADPH large subunit AB182_13415 ENOG4105D7T ABC transporter AB182_13435 ENOG41090EX DsrE family AB182_13440 ENOG4105C8Q Methyl-accepting chemotaxis AB182_13450 ENOG4108NH8 Cation transport protein AB182_13455 ENOG4105WS7 Cation transport regulator AB182_13460 ENOG4105EWV Sodium calcium exchanger membrane region AB182_13475 ENOG4105CMM transposase AB182_13490 ENOG4108ZSJ is1 orf2 AB182_13510 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase AB182_13515 ENOG41063JG Transcriptional regulator AB182_13520 ENOG4108YY7 Invasion gene expression up-regulator SirB AB182_13525 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AB182_13535 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) AB182_13540 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) AB182_13550 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AB182_13555 ENOG4105CHH sulfate transporter AB182_13565 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria AB182_13570 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) AB182_13575 ENOG4105C3G gtp-binding protein AB182_13580 ENOG4105DFP Integrase AB182_13585 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein AB182_13590 ENOG4105EGI Transcriptional regulator AB182_13605 ENOG41085W3 Transposase AB182_13625 ENOG41085W3 Transposase AB182_13630 ENOG4105CMM transposase AB182_13640 ENOG4105ETE Transcriptional regulator (LacI family AB182_13645 ENOG4108HKT sucrose-6-phosphate hydrolase AB182_13665 ENOG4105CT4 transporter AB182_13695 ENOG41090WB Transposase is3 is911 AB182_13715 ENOG4105W5Q DNA repair protein (RadC AB182_13735 ENOG4105HVQ Regulatory factor of maltose metabolism AB182_13795 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB182_13890 ENOG41088T4 Helicase IV AB182_13895 ENOG4105DZR Type I site-specific deoxyribonuclease AB182_13905 ENOG4105EKX Restriction modification system DNA (Specificity AB182_13910 ENOG4105CVR type I restriction-modification system AB182_13930 ENOG4105C0D helicase AB182_13955 ENOG4105CHR reductase AB182_13960 ENOG4105C7K acetolactate synthase AB182_13980 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AB182_13985 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) AB182_13990 ENOG4107QR9 Iron-sulfur cluster binding protein AB182_13995 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) AB182_14010 ENOG4105DJB Major Facilitator Superfamily AB182_14015 ENOG4105KME endoribonuclease L-psp AB182_14025 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) AB182_14030 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AB182_14045 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) AB182_14050 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase AB182_14055 ENOG4105DUM transcriptional regulator, lysR family AB182_14070 ENOG4105F38 ABC transporter, permease AB182_14075 ENOG4105D38 putrescine abc transporter AB182_14080 ENOG4105H3G oxidoreductase AB182_14085 ENOG4105BZU Histidine kinase AB182_14090 ENOG4105C0A alcohol dehydrogenase AB182_14095 ENOG4105CC0 LysR family Transcriptional regulator AB182_14115 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AB182_14125 ENOG4105ETE Transcriptional regulator (LacI family AB182_14130 ENOG4105ECY inositol monophosphatase AB182_14135 ENOG4107QRT dEAD DEAH box helicase AB182_14155 ENOG4107QRI Phosphoketolase AB182_14175 ENOG4108Z9Z response to DNA damage stimulus AB182_14180 ENOG4108N8X transition metal ion binding AB182_14185 ENOG4105WEF catalase AB182_14190 ENOG4105C4M (Ubiquinol oxidase) subunit I AB182_14195 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AB182_14200 ENOG4108WTK competence damage-inducible protein AB182_14205 ENOG4105E2A Dehydrogenase AB182_14210 ENOG4105DZG Dehydrogenase AB182_14245 ENOG4105ETT transcriptional Regulator, LysR family AB182_14260 ENOG4105ETT transcriptional Regulator, LysR family AB182_14275 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AB182_14280 ENOG4105C8Q Methyl-accepting chemotaxis AB182_14285 ENOG4105CHR reductase AB182_14305 ENOG4105EXG Transcriptional regulator AB182_14340 ENOG4105C2C drug resistance transporter, Bcr CflA AB182_14350 ENOG4105DQ4 alcohol dehydrogenase AB182_14355 ENOG4105BZS acriflavin resistance protein AB182_14360 ENOG4105EQ2 LysR family Transcriptional regulator AB182_14365 ENOG4105CGD Nad-dependent epimerase dehydratase AB182_14370 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AB182_14375 ENOG4105EJC lysr family transcriptional regulator AB182_14390 ENOG4105F27 Major Facilitator AB182_14405 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate AB182_14410 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism AB182_14415 ENOG4108MRH transcriptional regulatory protein AB182_14425 ENOG4108RS6 transposase AB182_14440 ENOG4107GFK fumarate AB182_14450 ENOG4107R1I NAD-dependent malic enzyme AB182_14465 ENOG4105CMT Dihydroxyacetone kinase AB182_14470 ENOG4108UTZ Dihydroxyacetone kinase AB182_14495 ENOG4105CHR reductase AB182_14500 ENOG41061ZR Transcriptional regulator AB182_14510 ENOG4108PZW LysR family Transcriptional regulator AB182_14515 ENOG4105CC0 LysR family Transcriptional regulator AB182_14525 ENOG4105CHF Glutathione S-transferase AB182_14535 ENOG4105E1F short-chain dehydrogenase reductase AB182_14555 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF AB182_14560 ENOG4105C1P efflux transporter, rnd family, mfp subunit AB182_14585 ENOG4108IXY short-chain dehydrogenase reductase AB182_14590 ENOG4105CF7 AraC family transcriptional regulator AB182_14595 ENOG4108UY2 Chloramphenicol acetyltransferase AB182_14610 ENOG4108UQ8 endoribonuclease L-psp AB182_14620 ENOG4106NDP Transcriptional regulator AB182_14630 ENOG4108HKT sucrose-6-phosphate hydrolase AB182_14650 ENOG4105D7K pfkb domain protein AB182_14670 ENOG410642W LysR family Transcriptional regulator AB182_14675 ENOG4107SET aldo keto reductase AB182_14690 ENOG4107RTG Major Facilitator superfamily AB182_14695 ENOG4108MIW Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions AB182_14710 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB182_14715 ENOG4105CW7 secretion protein, HlyD family AB182_14720 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes AB182_14730 ENOG4105EQ2 LysR family Transcriptional regulator AB182_14740 ENOG4107RTG Major Facilitator superfamily AB182_14745 ENOG4105DQ4 alcohol dehydrogenase AB182_14750 ENOG4105ENX hydrolase AB182_14755 ENOG4105CPC Aldo Keto reductase AB182_14790 ENOG4106GZG polymyxin resistance protein B AB182_14810 ENOG4105EHI Phosphonate ABC transporter, periplasmic AB182_14820 ENOG4105S7S phosphonate abc transporter AB182_14830 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) AB182_14835 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) AB182_14840 ENOG4105EHG Permease protein AB182_14850 ENOG4106QJH hemin transport protein AB182_14865 ENOG4105WWK YheO domain protein AB182_14895 ENOG4105C26 Dehydrogenase AB182_14900 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family AB182_14905 ENOG41089BK Glutamine amido-transferase AB182_14915 ENOG4105CKK Glycosyl transferase, family 2 AB182_14920 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) AB182_14940 ENOG4105CNA YD repeat protein AB182_14970 ENOG4105CNA YD repeat protein AB182_15035 ENOG41065RQ ADP-ribosylation crystallin J1 AB182_15040 ENOG4108X1T PAAR repeat-containing protein AB182_15050 ENOG4105CS6 Rhs element vgr protein AB182_15055 ENOG41065RQ ADP-ribosylation crystallin J1 AB182_15125 ENOG4105D9P serine threonine protein kinase AB182_15130 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB182_15175 ENOG4108WC9 type VI secretion system effector, hcp1 family AB182_15215 ENOG4106VK6 Flagellar motor protein AB182_15235 ENOG4105E53 ec 3.2.1.28 AB182_15250 ENOG4105CMM transposase AB182_15255 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) AB182_15260 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division AB182_15265 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A AB182_15270 ENOG4105C3N Participates in control of cell volume in low-osmolarity conditions (By similarity) AB182_15275 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AB182_15280 ENOG4105MWK D-amino acid dehydrogenase, small subunit AB182_15285 ENOG4105ED1 spovr family AB182_15290 ENOG4105C05 Multifunctional regulator of fatty acid metabolism (By similarity) AB182_15305 ENOG4108ZZ3 UPF0260 protein AB182_15310 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase AB182_15315 ENOG4105VNG YcgL domain-containing protein AB182_15320 ENOG4105K7U Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) AB182_15325 ENOG4107QMS site-determining protein AB182_15330 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) AB182_15335 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) AB182_15340 ENOG4105CEY Amp-dependent synthetase and ligase AB182_15345 ENOG4105Y4Z Outer Membrane Lipoprotein AB182_15350 ENOG41072GX Peptidase M22 Glycoprotease AB182_15355 ENOG4105DVT helicase AB182_15360 ENOG4105M4H endoribonuclease L-psp AB182_15370 ENOG4105X5C UPF0181 protein AB182_15375 ENOG4105CRQ synthase (Component I) AB182_15380 ENOG4105P8F nudix hydrolase AB182_15385 ENOG4105EJQ L-serine dehydratase AB182_15390 ENOG4107XTP (EAL) domain protein AB182_15395 ENOG4105EE5 Membrane protein terC AB182_15400 ENOG4108EQA pts system AB182_15405 ENOG4105ETZ PTS System AB182_15410 ENOG4105F3R pts system mannose fructose sorbose family iid AB182_15420 ENOG4108UI1 Probably functions as a manganese efflux pump (By similarity) AB182_15425 ENOG4105DHI Methyltransferase AB182_15430 ENOG4105VEQ Cold shock protein AB182_15440 ENOG4105Q3Y exported protein AB182_15445 ENOG4105TIK AB182_15450 ENOG4105J4Q Transcriptional regulator AB182_15455 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB182_15465 ENOG4105CN1 protease AB182_15475 ENOG4108ZGC gaf domain protein AB182_15480 ENOG4105H2K paraquat-inducible protein a AB182_15485 ENOG4105DY2 Paraquat-inducible protein b AB182_15490 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B AB182_15495 ENOG4105WT8 Protein of unknown function (DUF1480) AB182_15500 ENOG4105UVW uncharacterized protein yebW AB182_15505 ENOG4108R1E Serine threonine protein phosphatase 1 AB182_15510 ENOG4108MJ5 VirK protein AB182_15520 ENOG4108RS6 transposase AB182_15535 ENOG4105CMM transposase AB182_15540 ENOG4105NKT exported protein AB182_15545 ENOG4108PNC copper resistance AB182_15550 ENOG4105FXM Copper resistance protein AB182_15555 ENOG4105MPK DNA polymerase III subunit theta AB182_15560 ENOG4105UMD exodeoxyribonuclease X AB182_15565 ENOG4105CUG Oligopeptidase b AB182_15570 ENOG4108Q2J Inner membrane protein YebE AB182_15580 ENOG4105X2V dna damage-inducible protein AB182_15595 ENOG4108VEV chaperone AB182_15600 ENOG4108UHU Aldolase AB182_15605 ENOG4105C01 Dihydroxy-acid dehydratase AB182_15610 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase AB182_15615 ENOG4106KNT transcriptional regulator AB182_15620 ENOG4105CA9 Pyruvate kinase AB182_15625 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase AB182_15630 ENOG4105DR5 peptidase AB182_15635 ENOG4105NXV High-affinity zinc uptake system protein AB182_15645 ENOG4105FAV ABC, transporter AB182_15650 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) AB182_15655 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) AB182_15670 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) AB182_15675 ENOG4105CDY transcriptional regulatory protein AB182_15680 ENOG4108TIT dATP pyrophosphohydrolase AB182_15685 ENOG4105C9M aspartyl-trna synthetase AB182_15690 ENOG4105D3W isochorismatase AB182_15695 ENOG41081XQ Conserved Protein AB182_15700 ENOG4105WJG Glutathione AB182_15710 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) AB182_15720 ENOG4106ZCM YecM protein AB182_15725 ENOG4107SEY Conserved Protein AB182_15745 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AB182_15760 ENOG4107FW0 short-chain dehydrogenase reductase AB182_15770 ENOG4108XDN Transcriptional regulator AB182_15775 ENOG4105C75 arginyL-tRNA synthetase AB182_15785 ENOG4105F5H Glycosyl Hydrolase Family 88 AB182_15790 ENOG4105CT4 transporter AB182_15795 ENOG4105IRD Flagellar protein FlhE AB182_15800 ENOG4105D7B Flagellar biosynthesis protein flha AB182_15805 ENOG4105D00 flagellar biosynthetic protein flhB AB182_15815 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) AB182_15820 ENOG4108VYJ response regulator receiver protein AB182_15830 ENOG4105BZU Histidine kinase AB182_15835 ENOG4105C8Q Methyl-accepting chemotaxis AB182_15840 ENOG4105C8Q Methyl-accepting chemotaxis AB182_15845 ENOG4108V3W Chemotaxis protein, CheW AB182_15850 ENOG4105CBS Chea signal transduction histidine kinase AB182_15855 ENOG4105ER2 Ompa motb domain protein AB182_15860 ENOG4107RD7 Flagellar Motor Protein, MotA AB182_15865 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region AB182_15870 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) AB182_15875 ENOG4108VA4 Universal stress protein AB182_15880 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase AB182_15885 ENOG4108K4C ec 3.1.3.12 AB182_15890 ENOG4105CNN ABC, transporter AB182_15900 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator AB182_15910 ENOG41090A1 ferritin AB182_15915 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AB182_15925 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase AB182_15930 ENOG4105P23 (LipO)protein AB182_15935 ENOG41090A1 ferritin AB182_15940 ENOG4105VVZ metal-binding protein AB182_15945 ENOG4105E0U tyrosine-specific transport protein AB182_15950 ENOG4106RHG Yeca family AB182_15955 ENOG4105D5M phosphate starvation-inducible protein AB182_15960 ENOG4105DBE peroxidase AB182_15965 ENOG410650H (LipO)protein AB182_15970 ENOG4105EKT )-iron permease AB182_15975 ENOG4105D9N nucleoside AB182_15990 ENOG4108VEV chaperone AB182_15995 ENOG4105CK7 Sodium proline symporter AB182_16000 ENOG4105C26 Dehydrogenase AB182_16010 ENOG4108R86 Transcriptional regulator AB182_16015 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) AB182_16020 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) AB182_16025 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) AB182_16030 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) AB182_16040 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) AB182_16065 ENOG4105CF7 AraC family transcriptional regulator AB182_16070 ENOG4105CHR reductase AB182_16100 ENOG4106JA9 AB182_16105 ENOG4106J3D AB182_16130 ENOG4107QSI ABC, transporter AB182_16135 ENOG4108MN8 Membrane AB182_16145 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 AB182_16155 ENOG4108V1U phospholipid-binding protein AB182_16165 ENOG4105GSS Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity) AB182_16170 ENOG4105K4P CoA-binding domain protein AB182_16175 ENOG4108Q67 UPF0319 protein AB182_16185 ENOG41088T4 Helicase IV AB182_16190 ENOG410901E Membrane AB182_16195 ENOG4105EM2 membrane AB182_16200 ENOG4108RZ1 DNA transformation protein AB182_16205 ENOG4108ZD2 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity) AB182_16210 ENOG4105UYK outer membrane protein a AB182_16215 ENOG4108R9Q Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity) AB182_16220 ENOG4105DAN ATP-dependent protease AB182_16230 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) AB182_16235 ENOG4108Q2G (LipO)protein AB182_16240 ENOG4105DY2 Paraquat-inducible protein b AB182_16245 ENOG4105F1S paraquat-inducible protein a AB182_16250 ENOG4105C5H ABC transporter AB182_16255 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) AB182_16260 ENOG4105QVC MOSC domain-containing protein AB182_16265 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) AB182_16270 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) AB182_16275 ENOG4108UZX fmn reductase AB182_16280 ENOG4105CD8 aminopeptidase N AB182_16285 ENOG4105Y50 Virulence Protein AB182_16305 ENOG4108ZSJ is1 orf2 AB182_16325 ENOG4105QFS Lysis protein S homolog from lambdoid prophage AB182_16415 ENOG4107R08 Integrase AB182_16420 ENOG4107RH7 Nicotinate phosphoribosyltransferase AB182_16430 ENOG4107RCH Diaminopropionate ammonia-lyase AB182_16440 ENOG4105C5S asparaginyl-tRNA synthetase AB182_16445 ENOG4108RS6 transposase AB182_16455 ENOG4105CGF Aromatic amino acid aminotransferase AB182_16460 ENOG4105C5X domain protein AB182_16465 ENOG4105EAQ (twin-arginine translocation) pathway signal AB182_16470 ENOG4105DIT ErfK YbiS YcfS YnhG family protein AB182_16480 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) AB182_16485 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) AB182_16490 ENOG4106371 Methyltransferase AB182_16495 ENOG4107S90 membrAne AB182_16500 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups AB182_16505 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) AB182_16510 ENOG4105W49 UPF0434 protein AB182_16515 ENOG4105T0Z Conserved Protein AB182_16520 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) AB182_16530 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 AB182_16535 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) AB182_16540 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) AB182_16545 ENOG4105CAT Cytidine monophosphate kinase AB182_16550 ENOG4108K0D peptidase, M48 AB182_16560 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) AB182_16565 ENOG4107VMU Membrane AB182_16570 ENOG4105DDY UPF0142 protein ycaO AB182_16575 ENOG4105TMB Formate nitrite transporter AB182_16580 ENOG4105C6N Formate acetyltransferase AB182_16585 ENOG4105F1A Pyruvate formate-lyase AB182_16595 ENOG4108ISG Major Facilitator AB182_16600 ENOG4107KGK dmso reductase anchor subunit AB182_16605 ENOG4105QAX Iron-sulfur AB182_16610 ENOG4107QY8 reductase AB182_16615 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) AB182_16620 ENOG4105D1H recombination factor protein RarA AB182_16630 ENOG4105CNU cell division protein FtsK AB182_16635 ENOG4105EW9 transcriptional regulator AsnC family AB182_16640 ENOG4105C3M thioredoxin reductase AB182_16645 ENOG4108JJ9 ABC, transporter AB182_16650 ENOG4108JJ8 (ABC) transporter AB182_16655 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) AB182_16660 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) AB182_16665 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB182_16675 ENOG4105VEQ Cold shock protein AB182_16685 ENOG4105DJY efflux transporter, rnd family, mfp subunit AB182_16690 ENOG4108MJ5 VirK protein AB182_16695 ENOG4105CPB ATP-dependent endonuclease of the OLD family AB182_16700 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) AB182_16705 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) AB182_16710 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AB182_16720 ENOG4105C7K acetolactate synthase AB182_16725 ENOG4105C5W Aldolase AB182_16730 ENOG4105CGD Nad-dependent epimerase dehydratase AB182_16735 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase AB182_16740 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase AB182_16745 ENOG4105K8R UPF0145 protein AB182_16750 ENOG41064MM (LipO)protein AB182_16755 ENOG4105E5Z arginine transporter ATP-binding subunit AB182_16760 ENOG4106PMH Extracellular solute-binding protein family 3 AB182_16765 ENOG4105GBT ABC transporter AB182_16770 ENOG4105DMR ABC, transporter AB182_16775 ENOG4106TNF Periplasmic binding protein AB182_16780 ENOG4105BZU Histidine kinase AB182_16785 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB182_16800 ENOG4107SFS Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity) AB182_16805 ENOG4105RBQ inner membrane protein ybjO AB182_16810 ENOG4105D38 putrescine abc transporter AB182_16815 ENOG4105F38 ABC transporter, permease AB182_16820 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AB182_16825 ENOG4107RUE extracellular solute-binding protein family 1 AB182_16830 ENOG4108RMJ sensory transduction regulator AB182_16835 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) AB182_16840 ENOG4108DBC nitroreductase AB182_16845 ENOG41090BQ Glutaredoxin AB182_16850 ENOG4105GWF inner membrane protein YbjM AB182_16855 ENOG4105D0C transport protein AB182_16870 ENOG4108RFG Tetr family transcriptional regulator AB182_16875 ENOG4106UW1 Major Facilitator superfamily AB182_16895 ENOG4105E0F Histidine kinase AB182_16910 ENOG4107QF7 multi-drug AB182_16915 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase AB182_16920 ENOG4107FB0 transcriptional regulator DeoR family AB182_16935 ENOG4105DZ1 carboxypeptidase AB182_16940 ENOG4108TGY Glutathione S-transferase AB182_16945 ENOG4105D8V Glucose sorbosone dehydrogenase AB182_16950 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway AB182_16960 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AB182_16965 ENOG4105EIG urea carboxylase-associated protein 1 AB182_16975 ENOG4108IJ6 ABC transporter AB182_16985 ENOG4107UWC ABC, transporter AB182_17005 ENOG4105DJB Major Facilitator Superfamily AB182_17010 ENOG4105C5I Dehydrogenase AB182_17015 ENOG4106NZI LysR family Transcriptional regulator AB182_17020 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB182_17025 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AB182_17030 ENOG4105DEF Extracellular solute-binding protein, family 5 AB182_17035 ENOG4108JQ6 ABC transporter AB182_17040 ENOG4105D44 asparaginase AB182_17045 ENOG4105CVM Molybdenum cofactor synthesis domain protein AB182_17050 ENOG4105D06 uba thif-type nad fad binding protein AB182_17055 ENOG4105F1A Pyruvate formate-lyase AB182_17060 ENOG4105C6N Formate acetyltransferase AB182_17065 ENOG4108HCJ Hydrolase AB182_17070 ENOG41072TH Protein of unknown function (DUF1479) AB182_17075 ENOG4105ETE Transcriptional regulator (LacI family AB182_17080 ENOG4105DPW Major facilitator superfamily MFS_1 AB182_17090 ENOG4105C5H ABC transporter AB182_17095 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AB182_17100 ENOG4108TZY GntR Family Transcriptional Regulator AB182_17105 ENOG4105CK1 PTS System AB182_17110 ENOG4105CS2 ec 3.2.1.21 AB182_17115 ENOG4105CPC Aldo Keto reductase AB182_17125 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB182_17130 ENOG4105CW7 secretion protein, HlyD family AB182_17135 ENOG4105F4P )-transporter AB182_17140 ENOG4105KST dependent repressor AB182_17155 ENOG4108I6E Sulfatase AB182_17160 ENOG4108T1M outer membrane protein x AB182_17170 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction AB182_17175 ENOG4107R0W ABC transporter AB182_17180 ENOG4105E5Q amino acid AbC transporter AB182_17185 ENOG4105CDA abc transporter atp-binding protein AB182_17190 ENOG4105D8X mechanosensitive ion channel AB182_17195 ENOG4105EBA Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity) AB182_17200 ENOG4105EW6 flavin reductase domain protein, FMN-binding AB182_17205 ENOG4105KSC Transcriptional regulator, TraR DksA family AB182_17210 ENOG4105VR4 UPF0379 protein ybiJ AB182_17215 ENOG4108MTB glycosyl transferase family AB182_17220 ENOG4105DVT helicase AB182_17225 ENOG4105CID antiterminator AB182_17235 ENOG4105CS2 ec 3.2.1.21 AB182_17240 ENOG4105CS2 ec 3.2.1.21 AB182_17255 ENOG4105C1J atp-dependent rna helicase AB182_17260 ENOG4107MVR Transcriptional regulator AB182_17265 ENOG4105D0S secretion protein (HlyD AB182_17270 ENOG4105CJ1 ABC, transporter AB182_17275 ENOG4107QWP ABC-2 type transporter AB182_17280 ENOG4107QWP ABC-2 type transporter AB182_17285 ENOG4105I9U inner membrane protein ybhQ AB182_17290 ENOG4105X23 Endonuclease Exonuclease phosphatase AB182_17295 ENOG4105DZQ phospholipase D Transphosphatidylase AB182_17300 ENOG4107UXM Membrane AB182_17310 ENOG4105HFZ Membrane AB182_17315 ENOG4108ZAF Molybdopterin AB182_17320 ENOG4105M00 molybdopterin converting factor, subunit 1 AB182_17325 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AB182_17330 ENOG4108RIR Molybdenum cofactor biosynthesis protein AB182_17335 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AB182_17340 ENOG4105CHW UPF0052 protein AB182_17345 ENOG4105DIJ Phosphoethanolamine transferase AB182_17350 ENOG4105XJC Two component transcriptional regulator (Winged helix family AB182_17355 ENOG4105ECM Sensor protein basS pmrB AB182_17360 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) AB182_17370 ENOG4108IV0 ABC, transporter AB182_17385 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AB182_17390 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) AB182_17395 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AB182_17405 ENOG4108V1U phospholipid-binding protein AB182_17410 ENOG4105NBR Pectinesterase AB182_17420 ENOG4108K4B hydrolase AB182_17425 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) AB182_17430 ENOG4105E0C molybdate abc transporter AB182_17435 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AB182_17440 ENOG410680R Protein of unknown function (DUF2592) AB182_17450 ENOG4105F4R Transcriptional regulator mode AB182_17455 ENOG4105DKW ABC transporter AB182_17460 ENOG4105CMR udp-glucose 4-epimerase AB182_17465 ENOG4105F0Z galactose-1-phosphate uridylyltransferase AB182_17470 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) AB182_17475 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) AB182_17485 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AB182_17490 ENOG4105JND homeobox protein AB182_17495 ENOG4105PGM cation diffusion facilitator family transporter AB182_17500 ENOG4106Z1T Nicotinamide Mononucleotide Transporter AB182_17505 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) AB182_17535 ENOG4105UFD tol-pal system protein YbgF AB182_17540 ENOG4105KCK Peptidoglycan-associated lipoprotein AB182_17550 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA AB182_17555 ENOG4105M8F Biopolymer transport protein exbD tolR AB182_17560 ENOG4105E02 MotA TolQ exbB proton channel AB182_17565 ENOG4107YD3 Thioesterase AB182_17570 ENOG4105KJB cyd operon protein YbgE AB182_17575 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AB182_17580 ENOG4105C4M (Ubiquinol oxidase) subunit I AB182_17595 ENOG4107YPT transcriptional regulator AB182_17600 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha AB182_17605 ENOG4105CMV Succinyl-CoA synthetase subunit beta AB182_17610 ENOG4105C7S Dehydrogenase AB182_17615 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 AB182_17620 ENOG4105E33 succinate dehydrogenase AB182_17625 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) AB182_17630 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein AB182_17635 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit AB182_17640 ENOG4105BZN citrate synthase AB182_17650 ENOG4105E7W lamb ycsf family protein AB182_17655 ENOG4107R7A Allophanate hydrolase subunit 2 AB182_17660 ENOG4105P4J Allophanate hydrolase, subunit 1 AB182_17665 ENOG4107QNR UPF0135 protein AB182_17670 ENOG4105CVP deoxyribo-dipyrimidine photolyase AB182_17675 ENOG4105XIQ Protein of unknown function (DUF2517) AB182_17685 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) AB182_17690 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) AB182_17695 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) AB182_17700 ENOG4105C08 Histidine kinase AB182_17705 ENOG4105EEX Two component transcriptional regulator (Winged helix family AB182_17710 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 AB182_17715 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) AB182_17720 ENOG4105EV9 Alpha Beta Hydrolase AB182_17725 ENOG4105NNH LexA regulated protein AB182_17730 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) AB182_17735 ENOG41090R7 Ferric uptake AB182_17740 ENOG4105GX6 (LipO)protein AB182_17755 ENOG4105CI1 PTS System AB182_17765 ENOG4105CE4 GlcNAc 6-P deacetylase AB182_17770 ENOG4105E2R ROK family AB182_17775 ENOG4105D4U had-superfamily hydrolase, subfamily iia AB182_17780 ENOG4105CAQ asparagine synthetase AB182_17820 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family AB182_17825 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AB182_17830 ENOG4105C9A Phoh family AB182_17835 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) AB182_17840 ENOG4108JU5 Magnesium and cobalt efflux protein AB182_17845 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) AB182_17850 ENOG4107RP9 extracellular solute-binding protein, family 3 AB182_17855 ENOG4105EAD ABC transporter AB182_17860 ENOG4105DRP amino acid AbC transporter AB182_17865 ENOG4105CDA abc transporter atp-binding protein AB182_17875 ENOG4107PAI alpha helical protein AB182_17890 ENOG4105DJF DNA polymerase III, delta' subunit AB182_17900 ENOG4107QZB decarboxylase AB182_17905 ENOG4108TGR phosphatase AB182_17910 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) AB182_17920 ENOG4105CJN penicillin-binding protein AB182_17925 ENOG4105CNI cell division protein FtsW AB182_17930 ENOG4105K6T rare lipoprotein A AB182_17935 ENOG4105DZ1 carboxypeptidase AB182_17940 ENOG4108Z43 UPF0250 protein AB182_17945 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) AB182_17950 ENOG41064T2 transcriptional regulator, lysR family AB182_17960 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) AB182_17965 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase AB182_17975 ENOG4105VEQ Cold shock protein AB182_17980 ENOG4105CEE C4-dicarboxylate transporter AB182_17985 ENOG4105KTS ribonuclease AB182_17990 ENOG4105NXH GreA GreB family elongation factor AB182_17995 ENOG4108U51 Universal stress protein AB182_18000 ENOG4108JU3 Alkyl hydroperoxide reductase AB182_18005 ENOG4105D3R alkyl hydroperoxide reductase AB182_18010 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase AB182_18015 ENOG4105BZV Phosphoadenosine phosphosulfate reductase AB182_18020 ENOG4105GTN ParB Domain Protein Nuclease AB182_18025 ENOG4105CHM Aminotransferase AB182_18030 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) AB182_18035 ENOG4106YVY Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity) AB182_18040 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) AB182_18060 ENOG4105CSH Transporter AB182_18065 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) AB182_18070 ENOG4105DUM transcriptional regulator, lysR family AB182_18075 ENOG4105EXG Transcriptional regulator AB182_18090 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) AB182_18095 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) AB182_18110 ENOG4105CNN ABC, transporter AB182_18115 ENOG4105C2J ABC transporter AB182_18120 ENOG4107SCQ Iron-containing alcohol dehydrogenase AB182_18125 ENOG41067SE Tetr family transcriptional regulator AB182_18130 ENOG4105CHR reductase AB182_18135 ENOG4105VCD cytoplasmic protein AB182_18140 ENOG4105D22 carbon starvation protein AB182_18145 ENOG41074DU domain protein AB182_18150 ENOG4108P2H Inner membrane protein YjiG AB182_18155 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) AB182_18165 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase AB182_18170 ENOG4105WQI isochorismatase AB182_18175 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase AB182_18180 ENOG4105E4F Isochorismate synthase AB182_18185 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein AB182_18190 ENOG4105E8G Major facilitator Superfamily AB182_18195 ENOG4105DQ5 transport system permease protein AB182_18200 ENOG4105TVJ transport system, permease AB182_18205 ENOG4105E0A ABC, transporter AB182_18220 ENOG4105C0W non-ribosomal peptide synthetase AB182_18225 ENOG41085A6 mbth domain-containing protein AB182_18230 ENOG4105E93 esterase AB182_18235 ENOG4107RNH Outer membrane receptor FepA AB182_18240 ENOG4108TSE Transferase AB182_18245 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AB182_18255 ENOG4105C2J ABC transporter AB182_18260 ENOG4105CNN ABC, transporter AB182_18270 ENOG4105GQR Chaperone AB182_18275 ENOG4105DKT Transcriptional regulator AB182_18280 ENOG4108HHA Transketolase AB182_18285 ENOG4108IUS Transketolase AB182_18295 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) AB182_18320 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A AB182_18335 ENOG4105CMM transposase AB182_18370 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AB182_18375 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB182_18380 ENOG4105C3U ABC transporter AB182_18385 ENOG4108JQ7 (ABC) transporter AB182_18390 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AB182_18395 ENOG4105EMU Dehydrogenase AB182_18405 ENOG4105E5Q amino acid AbC transporter AB182_18410 ENOG4105E5Q amino acid AbC transporter AB182_18430 ENOG4105WQ6 Membrane AB182_18440 ENOG4105HFT AraC family transcriptional regulator AB182_18450 ENOG41067SE Tetr family transcriptional regulator AB182_18455 ENOG4105MSB protein, conserved in bacteria AB182_18460 ENOG4107TIF Phenazine biosynthesis protein, PhzF family AB182_18480 ENOG4105ETE Transcriptional regulator (LacI family AB182_18495 ENOG4105EAA nucleoside AB182_18500 ENOG4105C85 amino acid AB182_18515 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AB182_18520 ENOG4108IY8 ABC, transporter AB182_18530 ENOG4105DG4 malate L-lactate dehydrogenase AB182_18555 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein AB182_18560 ENOG4105Q95 Cupin 2, conserved barrel domain protein AB182_18575 ENOG4108IY8 ABC, transporter AB182_18580 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AB182_18585 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AB182_18590 ENOG4107Z6I Thiamine biosynthesis protein AB182_18600 ENOG4105BZ8 glutamate synthase AB182_18605 ENOG4107SJI Dehydrogenase AB182_18610 ENOG4105CD3 dihydroorotase AB182_18615 ENOG4105CE7 Amidase, hydantoinase carbamoylase family AB182_18620 ENOG4105D58 Diguanylate phosphodiesterase AB182_18630 ENOG4105CW0 outer membrane usher protein AB182_18635 ENOG4105GQR Chaperone AB182_18670 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB182_18690 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction AB182_18695 ENOG4105HFT AraC family transcriptional regulator AB182_18700 ENOG4105C8Q Methyl-accepting chemotaxis AB182_18710 ENOG4105S5I Membrane AB182_18715 ENOG4105EXG Transcriptional regulator AB182_18720 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase AB182_18725 ENOG4105BZU Histidine kinase AB182_18730 ENOG4105C8Q Methyl-accepting chemotaxis AB182_18755 ENOG4105CKK Glycosyl transferase, family 2 AB182_18760 ENOG4105C3I Nad-dependent epimerase dehydratase AB182_18765 ENOG4105F73 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) AB182_18840 ENOG410829K Lysine exporter protein (Lyse ygga) AB182_18860 ENOG41090KR LysR family transcriptional Regulator AB182_18870 ENOG4105F2I Transposase AB182_18885 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase AB182_18895 ENOG4107QIJ Aconitate hydratase 2 AB182_18900 ENOG4107QPK )-transporter AB182_18910 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AB182_18915 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) AB182_18925 ENOG4105C8Q Methyl-accepting chemotaxis AB182_18940 ENOG4105BZU Histidine kinase AB182_18985 ENOG4105E5H Transposase AB182_18990 ENOG4108YXQ IS66 Orf2 family protein AB182_19025 ENOG4105FA0 parb-like partition protein AB182_19075 ENOG4106050 phage regulatory protein, rha family AB182_19170 ENOG4105NVB glycoside hydrolase, family 19 AB182_19215 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 AB182_19275 ENOG4105CMM transposase AB182_19325 ENOG4108KU3 Integrase AB182_19340 ENOG4105WQ3 Rna-binding protein AB182_19345 ENOG4105CI1 PTS System AB182_19350 ENOG4107P2S Transcriptional regulator AB182_19355 ENOG4105S2T inner membrane protein YbcI AB182_19365 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) AB182_19375 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) AB182_19380 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit AB182_19390 ENOG4108UMI ABC transporter, permease AB182_19400 ENOG4105D01 (LipO)protein AB182_19405 ENOG4105FCK Membrane AB182_19410 ENOG4105CV6 ABC transporter, permease AB182_19415 ENOG4108I0Y (ABC) transporter AB182_19420 ENOG4108UJV acyl-CoA thioesterase i AB182_19425 ENOG4105E1F short-chain dehydrogenase reductase AB182_19430 ENOG4107QR8 Thioredoxin AB182_19435 ENOG4107QX8 SPFH domain, Band 7 family protein AB182_19440 ENOG4105G5H Membrane AB182_19455 ENOG4108Z6Z Transcriptional regulator AB182_19460 ENOG4105C59 p-type ATPase AB182_19465 ENOG4105MBR gumn family AB182_19470 ENOG4108Z66 YbaK ebsC protein AB182_19475 ENOG4105CGH 5'-nucleotidase AB182_19480 ENOG4105EU0 Major facilitator Superfamily AB182_19485 ENOG4105CKD glutathione-regulated potassium-efflux system protein AB182_19490 ENOG4107RE1 Inosine-guanosine kinase AB182_19500 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) AB182_19510 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) AB182_19515 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) AB182_19520 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) AB182_19525 ENOG4107QMP dna polymerase iii subunits gamma and tau AB182_19530 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) AB182_19535 ENOG4105WD1 Membrane AB182_19540 ENOG4108URS primosomal replication protein n'' AB182_19545 ENOG4105EGS Mechanosensitive ion channel AB182_19550 ENOG4108IG5 Transcriptional regulator AB182_19555 ENOG4105C1P efflux transporter, rnd family, mfp subunit AB182_19560 ENOG4105BZS acriflavin resistance protein AB182_19565 ENOG4108UKR Biofilm formation regulator YbaJ AB182_19575 ENOG4108UW5 maltose o-acetyltransferase AB182_19580 ENOG4105GSJ Inner membrane protein ylaC AB182_19595 ENOG4105NRA 50s ribosomal protein l31 type b AB182_19605 ENOG4105D01 (LipO)protein AB182_19615 ENOG4108UMI ABC transporter, permease AB182_19620 ENOG4105C5Y PTS System AB182_19630 ENOG4105FDP GntR family transcriptional regulator AB182_19635 ENOG41066DG (EAL) domain protein AB182_19640 ENOG4105KCV RNA signal recognition particle 4.5S RNA AB182_19645 ENOG4105CNT hydrolase family 2 AB182_19650 ENOG4105ETE Transcriptional regulator (LacI family AB182_19665 ENOG4106ID6 AB182_19675 ENOG41080UX Methyltransferase AB182_19680 ENOG4108MNP Glycoprotein polysaccharide metabolism AB182_19685 ENOG4105C29 acyl-CoA thioesterase AB182_19690 ENOG4105BZU Histidine kinase AB182_19695 ENOG4108YZA Nitrogen regulatory protein pii AB182_19700 ENOG4105BZ1 (ABC) transporter AB182_19705 ENOG4105BZ1 (ABC) transporter AB182_19710 ENOG4108XM1 transcriptional regulator AsnC family AB182_19720 ENOG4108AZI Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity) AB182_19725 ENOG4108NFA extracellular solute-binding protein AB182_19735 ENOG4108TGP Thioesterase superfamily protein AB182_19740 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein AB182_19745 ENOG4105EIN peptidylprolyl cis-trans isomerase AB182_19750 ENOG4105K70 DNA-binding protein AB182_19755 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) AB182_19775 ENOG4105M85 Bola protein AB182_19780 ENOG4105IEY (LipO)protein AB182_19785 ENOG4105EYM Major Facilitator superfamily AB182_19790 ENOG4105QFC Hsc56 co-chaperone of HscC AB182_19795 ENOG4105F7F Chaperone AB182_19800 ENOG4105E2S oxidase) subunit II AB182_19805 ENOG4105BZ9 Cytochrome C oxidase, subunit I AB182_19810 ENOG4105CCU oxidase (Subunit III) AB182_19815 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) AB182_19825 ENOG4107RDB Major Facilitator AB182_19830 ENOG4108VPT UPF0234 protein AB182_19835 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) AB182_19840 ENOG4107S0N DJ-1 family AB182_19845 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) AB182_19855 ENOG4105CTB Polyprenyl synthetase AB182_19865 ENOG4105CPC Aldo Keto reductase AB182_19870 ENOG4108ZAI phosphatidylglycerophosphatase a AB182_19875 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) AB182_19880 ENOG4107YIM Involved in the transcription termination process (By similarity) AB182_19885 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) AB182_19890 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) AB182_19900 ENOG4108KIC (LipO)protein AB182_19905 ENOG4105DRB nucleoside-specific channel-forming protein AB182_19910 ENOG4105N1F Hnh endonuclease AB182_19915 ENOG4105D29 Helix-turn-helix type 11 domain protein AB182_19925 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AB182_19930 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AB182_19935 ENOG4105VIE preprotein translocase, subunit YajC AB182_19945 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) AB182_19950 ENOG4108ZYK Acyl carrier protein phosphodiesterase AB182_19965 ENOG4107R28 alpha amylase, catalytic region AB182_19970 ENOG4105C85 amino acid AB182_19975 ENOG4105CWM branched-chain amino acid transport system II carrier protein AB182_19980 ENOG4105BZU Histidine kinase AB182_19985 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB182_19990 ENOG4107RH8 nuclease SbcCD subunit D AB182_19995 ENOG4105EYH Exonuclease AB182_20010 ENOG4105DKQ ROK family AB182_20020 ENOG4105NBK UPF0345 protein AB182_20025 ENOG4105HBA AroM protein AB182_20030 ENOG4105SS3 AB182_20035 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) AB182_20040 ENOG4108UPT UPF0178 protein AB182_20045 ENOG4105II7 pyrroline-5-carboxylate reductase AB182_20055 ENOG4105BZU Histidine kinase AB182_20060 ENOG4105VIF phosphate starvation-inducible protein AB182_20065 ENOG4105G6Z alkaline phosphatase AB182_20070 ENOG4105RZQ Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway (By similarity) AB182_20085 ENOG4105CPF Cell wall formation (By similarity) AB182_20090 ENOG4105UNH Membrane AB182_20095 ENOG4105FR5 inner membrane protein YaiY AB182_20100 ENOG4107QS8 (LipO)protein AB182_20105 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 AB182_20115 ENOG4107R6D beta-lactam binding protein AmpH AB182_20120 ENOG4108PNB DNA-binding transcriptional regulator AB182_20125 ENOG4108NSE outer membrane autotransporter barrel AB182_20130 ENOG4105D52 delta-aminolevulinic acid dehydratase AB182_20140 ENOG4108KX4 response regulator AB182_20145 ENOG4105BZU Histidine kinase AB182_20150 ENOG4105CXY transporter AB182_20155 ENOG4105C4Y ABC transporter AB182_20160 ENOG4108KQ5 Integrase catalytic subunit AB182_20165 ENOG4107RCV ABC transporter, permease AB182_20170 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AB182_20175 ENOG4108UK5 Transposase AB182_20180 ENOG4107QK5 Homocysteine s-methyltransferase AB182_20190 ENOG4105CUB amino acid AB182_20195 ENOG4105CPD ethanolamine ammonia-lyase AB182_20200 ENOG4107FQ9 ethanolamine ammonia-lyase AB182_20210 ENOG4108QY0 Membrane AB182_20220 ENOG4108N3Q Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) AB182_20225 ENOG4105CSH Transporter AB182_20230 ENOG4105C5I Dehydrogenase AB182_20235 ENOG4105IKQ hydratase AB182_20245 ENOG4105FKQ transcriptional regulator AB182_20260 ENOG4105F0I Aminotransferase AB182_20265 ENOG4107S8C mandelate racemase muconate lactonizing AB182_20275 ENOG4105CP9 extracellular ligand-binding receptor AB182_20280 ENOG4105C32 Amino acid ABC transporter (Permease) AB182_20285 ENOG4105CF8 branched-chain amino acid ABC transporter, permease AB182_20290 ENOG4105C0Z ABC transporter AB182_20295 ENOG4108IV0 ABC, transporter AB182_20315 ENOG4105CSH Transporter AB182_20385 ENOG4105DJ2 Major Facilitator Superfamily AB182_20390 ENOG4108ZT1 Transcriptional regulator AB182_20410 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) AB182_20415 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) AB182_20420 ENOG4105FCK Membrane AB182_20435 ENOG4105DRP amino acid AbC transporter AB182_20440 ENOG4105DRP amino acid AbC transporter AB182_20445 ENOG4106TNF Periplasmic binding protein AB182_20470 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) AB182_20475 ENOG4105CIN aminoacyl-histidine dipeptidase AB182_20480 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AB182_20485 ENOG4105F7V ErfK ybiS ycfS ynhG family protein AB182_20490 ENOG4105E7A Glutamine amidotransferase AB182_20495 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) AB182_20500 ENOG4107QPN acyl-Coa dehydrogenase AB182_20505 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase AB182_20515 ENOG4105C5R Aminotransferase AB182_20525 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) AB182_20550 ENOG410633P Hydantoin racemase AB182_20560 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease AB182_20615 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB182_20630 ENOG4108KQ5 Integrase catalytic subunit AB182_20645 ENOG4108ZG0 Ompa motb domain protein AB182_20675 ENOG4107RZZ dna polymerase iii epsilon subunit AB182_20680 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) AB182_20685 ENOG4105D1A Methyltransferase AB182_20690 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AB182_20695 ENOG4105E9H Lytic Murein transglycosylase AB182_20700 ENOG4105F2W methyltransferase AB182_20705 ENOG4107NA1 Endonuclease Exonuclease phosphatase AB182_20710 ENOG4105HEI LysR family (Transcriptional regulator AB182_20730 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AB182_20765 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase AB182_20770 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AB182_20775 ENOG4108UMI ABC transporter, permease AB182_20780 ENOG4105D01 (LipO)protein AB182_20785 ENOG4108R8X outer membrane lipoprotein AB182_20790 ENOG4108R96 Methyltransferase, YaeB family AB182_20800 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion AB182_20805 ENOG4108YZN class I peptide chain release factor AB182_20810 ENOG4108VWS Yaeq family AB182_20815 ENOG4105W1I UPF0253 protein AB182_20820 ENOG4105M1T rho-binding antiterminator AB182_20825 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) AB182_20830 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase AB182_20835 ENOG4105CXN decarboxylase AB182_20840 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) AB182_20845 ENOG4105C0B DNA polymerase III (alpha subunit) AB182_20855 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AB182_20870 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AB182_20880 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane AB182_20890 ENOG4105KNE Phosphatidate cytidylyltransferase AB182_20900 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) AB182_20915 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) AB182_20920 ENOG4105CE9 30S ribosomal protein S2 AB182_20925 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AB182_20930 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) AB182_20940 ENOG4108T8E UPF0325 protein AB182_20945 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR AB182_20950 ENOG4105C0H protease AB182_20970 ENOG4105EN6 Membrane AB182_20980 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase AB182_20985 ENOG4105S6R Iron-hydroxamate transporter permease subunit AB182_20990 ENOG4105J76 Periplasmic binding protein AB182_20995 ENOG4105E0A ABC, transporter AB182_21000 ENOG4105E0K tonB-dependent siderophore receptor AB182_21005 ENOG4105BZ4 penicillin-binding protein AB182_21010 ENOG4105CQ7 ATP-dependent helicase AB182_21015 ENOG4107XID 2'-5' rna ligase AB182_21020 ENOG4105PW4 Sugar fermentation stimulation protein homolog AB182_21025 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters AB182_21030 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) AB182_21035 ENOG4105DJ0 Poly(A) Polymerase AB182_21040 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase AB182_21045 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) AB182_21050 ENOG4107R03 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) AB182_21055 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) AB182_21060 ENOG4107BJW polysaccharide deacetylase AB182_21065 ENOG4108YTN IIa component AB182_21070 ENOG4105E3A (ABC) transporter AB182_21075 ENOG4105DA5 (ABC) transporter AB182_21080 ENOG41077A9 carbonic anhydrase AB182_21085 ENOG4108UGV hypoxanthine phosphoribosyltransferase AB182_21090 ENOG4105DZG Dehydrogenase AB182_21095 ENOG4105E3B Multicopper oxidase AB182_21100 ENOG4108ZRK uncharacterized protein yacC AB182_21110 ENOG4105FDS Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) AB182_21120 ENOG4107QIJ Aconitate hydratase 2 AB182_21130 ENOG4107QN2 dihydrolipoyl dehydrogenase AB182_21135 ENOG4107QSN dihydrolipoamide acetyltransferase AB182_21140 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) AB182_21145 ENOG41073TP transcriptional regulator AB182_21150 ENOG4105C85 amino acid AB182_21155 ENOG4105CT4 transporter AB182_21160 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) AB182_21165 ENOG4106A72 regulatory protein AmpE AB182_21175 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase AB182_21180 ENOG4108ZUW Major pilin subunit AB182_21185 ENOG4107QHF type ii secretion system protein e AB182_21190 ENOG4105D7Q type ii secretion system AB182_21195 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AB182_21200 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) AB182_21205 ENOG4105DHA Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity) AB182_21215 ENOG4105M6F mutator MutT protein AB182_21225 ENOG4106Q9Y Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) AB182_21235 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) AB182_21240 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) AB182_21245 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) AB182_21250 ENOG4105CPF Cell wall formation (By similarity) AB182_21255 ENOG4105DFU Cell wall formation (By similarity) AB182_21260 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) AB182_21265 ENOG4105CNI cell division protein FtsW AB182_21275 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) AB182_21280 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) AB182_21285 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AB182_21290 ENOG4105CJN penicillin-binding protein AB182_21295 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) AB182_21305 ENOG4108V6E Cell division protein mraZ AB182_21310 ENOG4107B7Y DNA-binding transcriptional regulator FruR AB182_21315 ENOG4108ZP8 Acetolactate synthase small subunit AB182_21320 ENOG4105C7K acetolactate synthase AB182_21325 ENOG41064T2 transcriptional regulator, lysR family AB182_21345 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AB182_21355 ENOG4105E2X shikimate dehydrogenase AB182_21360 ENOG4105EMV Major Facilitator AB182_21365 ENOG4105FF2 Type I DHQase AB182_21370 ENOG4105CMU LysR family (Transcriptional regulator AB182_21375 ENOG4105DJB Major Facilitator Superfamily AB182_21380 ENOG4105S8Q sugar efflux transporter AB182_21390 ENOG4105DP9 ABC transporter AB182_21395 ENOG4106SMU thiamine transporter membrane protein AB182_21400 ENOG4107T0D ABC, transporter AB182_21405 ENOG4108KF1 Membrane AB182_21415 ENOG4105EF1 ribulokinase AB182_21420 ENOG4105CAC Catalyzes the conversion of L-arabinose to L-ribulose (By similarity) AB182_21425 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase AB182_21435 ENOG4105CQ2 DNA polymerase AB182_21440 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) AB182_21445 ENOG4105D3G Pseudouridine synthase AB182_21450 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) AB182_21455 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) AB182_21465 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) AB182_21470 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) AB182_21475 ENOG4105NWN ApaG protein AB182_21480 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) AB182_21485 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) AB182_21490 ENOG4105CKD glutathione-regulated potassium-efflux system protein AB182_21495 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF AB182_21500 ENOG4105M5B (LipO)protein AB182_21505 ENOG4105C54 Major Facilitator superfamily AB182_21510 ENOG4105WQV ferredoxin-like protein AB182_21515 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase AB182_21530 ENOG4105C94 Transporter AB182_21535 ENOG4105C1G acyl-Coa dehydrogenase AB182_21540 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AB182_21545 ENOG4105CEY Amp-dependent synthetase and ligase AB182_21550 ENOG4106YT9 Enoyl-CoA hydratase AB182_21555 ENOG4108Z0R Transferase AB182_21560 ENOG4108XNW Transcriptional activatory protein CaiF AB182_21565 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain AB182_21570 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain AB182_21585 ENOG4105EXG Transcriptional regulator AB182_21590 ENOG4105DU0 nucleoside hydrolase AB182_21600 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase AB182_21605 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) AB182_21610 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) AB182_21615 ENOG4105DTN riboflavin biosynthesis protein ribF AB182_21640 ENOG41063Z6 transcriptional regulator, lysR family AB182_21645 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) AB182_21650 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) AB182_21655 ENOG4105CFG Acts as a chaperone (By similarity) AB182_21660 ENOG4106HK8 GPR1 FUN34 yaaH family protein AB182_21670 ENOG4105EHG Permease protein AB182_21675 ENOG4108HWH (ABC) transporter AB182_21685 ENOG4105CSH Transporter AB182_21690 ENOG4108RIR Molybdenum cofactor biosynthesis protein AB182_21700 ENOG4105BZG amino acid carrier protein AB182_21705 ENOG4105D1Q UPF0246 protein AB182_21710 ENOG41062C6 Protein of unknown function (DUF2502) AB182_21715 ENOG4105D98 threonine synthase AB182_21725 ENOG4105CFH Aspartokinase AB182_21730 ENOG4106FVC RNA methyltransferase AB182_21735 ENOG41065U4 response regulator AB182_21740 ENOG4105CT7 inner membrane cred family protein AB182_21745 ENOG4105EB3 Histidine kinase AB182_21750 ENOG4105E3W Two component transcriptional regulator (Winged helix family AB182_21755 ENOG4108RH0 Crea protein AB182_21760 ENOG4105UEI Transcriptional Regulator AraC Family AB182_21775 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) AB182_21780 ENOG4107SC1 transglycosylase AB182_21785 ENOG4105C5H ABC transporter AB182_21795 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase AB182_21800 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) AB182_21805 ENOG4105EAC phosphoserine phosphatase AB182_21810 ENOG41062Z9 Membrane AB182_21815 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) AB182_21820 ENOG4105D3A purine nucleoside phosphorylase DeoD-type AB182_21840 ENOG4105G0K glycine radical enzyme YjjI family AB182_21845 ENOG41076CZ activating enzyme AB182_21850 ENOG4105EYA deoxyribonuclease AB182_21855 ENOG4108NRW Phospholipase, patatin family AB182_21860 ENOG4105K3G Periplasmic Protein AB182_21865 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) AB182_21870 ENOG4105PAD Hydrolase AB182_21875 ENOG4105KEG ribosomal-protein-alanine acetyltransferase AB182_21880 ENOG4108WPU DNA polymerase III subunit psi AB182_21905 ENOG4105YBH Protein of unknown function (DUF1435) AB182_21910 ENOG4105BZU Histidine kinase AB182_21915 ENOG4108819 ferric iron reductase AB182_21920 ENOG4105CK1 PTS System AB182_21925 ENOG4108UIN ybak prolyl-trna synthetase associated region AB182_21930 ENOG4108T94 DNA-binding transcriptional activator BglJ AB182_21935 ENOG4108N8T regulatoR AB182_21940 ENOG4105DWK Membrane AB182_21945 ENOG4107XM3 UPF0442 protein AB182_21955 ENOG4105K56 Transcriptional regulator AB182_21960 ENOG4108ZHJ Organic hydroperoxide resistance protein AB182_21965 ENOG4108PM0 it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity) AB182_21970 ENOG4106CVF DNA replication protein AB182_21975 ENOG4105RI1 glycoprotein receptor AB182_21980 ENOG4107RES phosphoglycerol transferase I AB182_21985 ENOG4105CPQ Dehydrogenase AB182_21990 ENOG410617M Transcriptional regulator AB182_21995 ENOG4108I5G Major Facilitator superfamily AB182_22000 ENOG4105KEG ribosomal-protein-alanine acetyltransferase AB182_22005 ENOG4105C8Q Methyl-accepting chemotaxis AB182_22010 ENOG4105D22 carbon starvation protein AB182_22015 ENOG4105VCD cytoplasmic protein AB182_22020 ENOG4105CKI cobalamin synthesis protein AB182_22045 ENOG4106BRA Membrane AB182_22050 ENOG41083G8 Multidrug resistance protein MdtM AB182_22055 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase AB182_22060 ENOG4105CIZ coA-substrate-specific enzyme activase AB182_22095 ENOG4105CMM transposase AB182_22100 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB182_22120 ENOG4108F3G Type I restriction-modification system, R subunit AB182_22130 ENOG4107QTH restriction modification system DNA specificity domain AB182_22150 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) AB182_22170 ENOG4107Z3H Transcriptional regulator, TetR family AB182_22190 ENOG4105DUM transcriptional regulator, lysR family AB182_22195 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF AB182_22205 ENOG4108S10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AB182_22210 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB182_22220 ENOG4105E7U AraC family transcriptional regulator AB182_22225 ENOG4108KQ5 Integrase catalytic subunit AB182_22235 ENOG4105EZE Cupin 4 family protein AB182_22260 ENOG4105YCT UPF0386 protein AB182_22265 ENOG4107HP6 Transcriptional regulator AB182_22270 ENOG4105DSG hydrolase family 43 AB182_22275 ENOG4105CT4 transporter AB182_22280 ENOG4105C01 Dihydroxy-acid dehydratase AB182_22320 ENOG4105DQ4 alcohol dehydrogenase AB182_22330 ENOG4108K5H permease YjgP YjgQ family protein AB182_22335 ENOG4108M8S permease YjgP YjgQ family protein AB182_22340 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) AB182_22345 ENOG4105MYG DNA polymerase iii, chi subunit AB182_22350 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) AB182_22355 ENOG4108M3P Membrane AB182_22360 ENOG4108M3P Membrane AB182_22365 ENOG4108MJ3 acetyltransferase AB182_22375 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase AB182_22380 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) AB182_22390 ENOG4105XEP YhcH YjgK YiaL family protein AB182_22395 ENOG4105CXT aspartate transcarbamylase AB182_22400 ENOG4108R9M Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity) AB182_22405 ENOG4105KME endoribonuclease L-psp AB182_22410 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic AB182_22415 ENOG4105D4X repressor AB182_22420 ENOG4105C5Y PTS System AB182_22425 ENOG4105CG3 alpha amylase, catalytic region AB182_22435 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase AB182_22440 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) AB182_22450 ENOG4108VEV chaperone AB182_22465 ENOG4105EMD TRANSCRIPTIONal AB182_22480 ENOG41069H0 dihydroorotase EC 3.5.2.3 AB182_22510 ENOG4105EXG Transcriptional regulator AB182_22515 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein AB182_22525 ENOG4105CMS peptidase U62, modulator of DNA gyrase AB182_22530 ENOG4105N42 UPF0307 protein AB182_22540 ENOG4105DFU Cell wall formation (By similarity) AB182_22545 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 AB182_22555 ENOG4105C8Q Methyl-accepting chemotaxis AB182_22560 ENOG41062B0 ABC transporter, permease AB182_22565 ENOG4107R9N ABC transporter AB182_22570 ENOG4105C2J ABC transporter AB182_22575 ENOG4108KQ5 Integrase catalytic subunit AB182_22580 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator AB182_22585 ENOG4105F0N pyrophosphate phospho-hydrolase AB182_22590 ENOG4108NVR Methyl-accepting chemotaxis AB182_22600 ENOG4108RS6 transposase AB182_22605 ENOG4108ZHD aig2 family AB182_22610 ENOG4105MA0 exported protein AB182_22615 ENOG4105CFU surface antigen AB182_22635 ENOG4105C37 (CBS) domain AB182_22640 ENOG41061GZ Protein of unknown function (DUF1107) AB182_22645 ENOG4108UUE Transcriptional regulator AB182_22650 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase AB182_22655 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic AB182_22660 ENOG4105KVH Transcriptional regulator AB182_22665 ENOG4105ECR NmrA family AB182_22675 ENOG4105DXC membrane AB182_22690 ENOG4108V1T peptidylprolyl cis-trans isomerase AB182_22695 ENOG4105FHY Opacity-associated protein A AB182_22705 ENOG4105K9Q Binds to the 23S rRNA (By similarity) AB182_22710 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) AB182_22715 ENOG4108VDV Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity) AB182_22720 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) AB182_22725 ENOG4105KIT UPF0379 protein yjfY AB182_22755 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport AB182_22760 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC AB182_22775 ENOG4108MXZ Esterase AB182_22780 ENOG4105WSB biofilm stress and motility protein A AB182_22785 ENOG4105S17 UPF0379 protein yjfN AB182_22790 ENOG4105C8Q Methyl-accepting chemotaxis AB182_22795 ENOG4105CSU acyl-Coa dehydrogenase AB182_22800 ENOG4105CSH Transporter AB182_22805 ENOG4106032 Glutathionylspermidine synthase AB182_22810 ENOG4108KXT Conserved Protein AB182_22815 ENOG4105Z6B inner membrane protein yjfl AB182_22825 ENOG4105C2N RNA methyltransferase TrmH family group 3 AB182_22835 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AB182_22855 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) AB182_22865 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis AB182_22875 ENOG4105EPW hflc protein AB182_22880 ENOG4107QJR hflk protein AB182_22885 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) AB182_22890 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) AB182_22895 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) AB182_22900 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) AB182_22905 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AB182_22910 ENOG4105K8N protein family UPF0079, ATPase AB182_22915 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) AB182_22940 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) AB182_22955 ENOG4105EGS Mechanosensitive ion channel AB182_22960 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) AB182_22970 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) AB182_22975 ENOG4105E33 succinate dehydrogenase AB182_22980 ENOG4108WJH Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) AB182_22990 ENOG4105QNF Outer membrane lipoprotein AB182_23020 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein AB182_23025 ENOG4105MTB Uncharacterized protein YjeJ AB182_23030 ENOG4105C8Q Methyl-accepting chemotaxis AB182_23035 ENOG4108ZVF (LipO)protein AB182_23045 ENOG4105EKQ RNA-directed DNA polymerase AB182_23060 ENOG4105DVH amino acid AB182_23065 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 AB182_23070 ENOG4108IJ0 Aspartate ammonia-lyase AB182_23075 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AB182_23080 ENOG4105VF7 tolerance protein AB182_23090 ENOG4108SIC Transcriptional regulator AB182_23110 ENOG4105D7X high-affinity nickel-transporter AB182_23115 ENOG4105CSH Transporter AB182_23120 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) AB182_23125 ENOG4108YIV AB182_23130 ENOG4108F5E vimentin AB182_23135 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA AB182_23150 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) AB182_23165 ENOG4108YZG isomerase AB182_23170 ENOG4105NYY transcriptional regulator, RpiR AB182_23175 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AB182_23180 ENOG4105C2J ABC transporter AB182_23185 ENOG4105CNN ABC, transporter AB182_23190 ENOG4105UP7 3-epimerase AB182_23195 ENOG4107TFG D-allose kinase AB182_23205 ENOG4105C2J ABC transporter AB182_23210 ENOG4105CNN ABC, transporter AB182_23215 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AB182_23225 ENOG4105D2N Aldolase AB182_23235 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AB182_23240 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB182_23245 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB182_23260 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase AB182_23265 ENOG4105E98 transcriptional regulator DeoR family AB182_23270 ENOG4105CK2 sodium dicarboxylate symporter AB182_23275 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AB182_23280 ENOG41062QD Membrane AB182_23285 ENOG4107QN1 sodium solute AB182_23290 ENOG4105DDC Oxidoreductase domain protein AB182_23295 ENOG41067MG lrgb family AB182_23305 ENOG4105CMU LysR family (Transcriptional regulator AB182_23310 ENOG4105EEQ Na H antiporter AB182_23315 ENOG4105C7N Xanthine uracil vitamin C permease AB182_23325 ENOG4108Z4X TRANSCRIPTIONal AB182_23330 ENOG4108W3Q Transcriptional regulator AB182_23335 ENOG4108M8H domain protein AB182_23340 ENOG4108ZSJ is1 orf2 AB182_23350 ENOG4105PMV Membrane AB182_23355 ENOG4108UUM single-stranded DNA-binding protein AB182_23360 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AB182_23365 ENOG4105MSB protein, conserved in bacteria AB182_23370 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme AB182_23375 ENOG4105F0S class B acid phosphatase AB182_23380 ENOG4105CGF Aromatic amino acid aminotransferase AB182_23385 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AB182_23390 ENOG4105CDU Replicative dna helicase AB182_23395 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein AB182_23400 ENOG4105P4Z Phage shock protein G AB182_23405 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AB182_23420 ENOG4105MYN Zinc uptake regulation protein AB182_23425 ENOG4105VDW Csbd family AB182_23430 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) AB182_23435 ENOG41080IJ Diacylglycerol kinase AB182_23440 ENOG4105E55 glycerol-3-phosphate acyltransferase AB182_23450 ENOG4105VEI Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity) AB182_23455 ENOG4107W52 maltose operon periplasmic protein AB182_23460 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) AB182_23470 ENOG4107FKK extracellular solute-binding protein family 1 AB182_23475 ENOG4105D56 permease protein AB182_23480 ENOG4105EG2 ABC transporter, permease AB182_23485 ENOG4108VY7 phosphate-starvation-inducible protein PsiE AB182_23495 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) AB182_23500 ENOG4105E3R (LipO)protein AB182_23505 ENOG4108Q9C Periplasmic Protein AB182_23510 ENOG4108MDC (LipO)protein AB182_23520 ENOG4107QP8 phosphohexose isomerase AB182_23525 ENOG4105CFH Aspartokinase AB182_23530 ENOG410756H nucleotidyltransferase AB182_23535 ENOG4105E0Y RtcB Protein AB182_23545 ENOG4105CYB regulatoR AB182_23550 ENOG4105C09 Bile acid AB182_23555 ENOG4108ZR5 Conserved Protein AB182_23560 ENOG4105FE9 pseudouridine synthase AB182_23565 ENOG4105DKT Transcriptional regulator AB182_23570 ENOG4105CHR reductase AB182_23575 ENOG4108XCU pts system AB182_23580 ENOG4105KPI PTS system sorbose subfamily IIB component AB182_23585 ENOG4105ETZ PTS System AB182_23590 ENOG4105F3R pts system mannose fructose sorbose family iid AB182_23595 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein AB182_23600 ENOG4105F9E Shikimate 5-dehydrogenase AB182_23615 ENOG4105EAM Na Pi-cotransporter AB182_23630 ENOG4105EJQ L-serine dehydratase AB182_23635 ENOG4105C44 Serine transporter AB182_23640 ENOG4105C3R Methionine synthase AB182_23645 ENOG41069M3 Transcriptional regulator AB182_23660 ENOG4108I9X Isocitrate lyase AB182_23665 ENOG4107QP3 malate synthase g AB182_23670 ENOG4105CVG Homoserine O-transsuccinylase AB182_23675 ENOG4105K5X acetyltransferase AB182_23680 ENOG41062WK cellular response to acidity AB182_23705 ENOG4105DC1 bifunctional purine biosynthesis protein purh AB182_23710 ENOG4105C12 Phosphoribosylglycinamide synthetase AB182_23720 ENOG4105BZU Histidine kinase AB182_23725 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism AB182_23730 ENOG4108T8B Protein of unknown function (DUF1481) AB182_23735 ENOG4105K70 DNA-binding protein AB182_23740 ENOG4105R2J Conserved Protein AB182_23755 ENOG4105E09 nadh pyrophosphatase AB182_23760 ENOG4107MNS Has binding activity to the major sigma subunit of RNA polymerase. May be involved in replacement of the RNA polymerase sigma subunit from sigma-70 to sigma-S during the transition from exponential growth to the stationary phase (By similarity) AB182_23765 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) AB182_23775 ENOG4105D06 uba thif-type nad fad binding protein AB182_23780 ENOG4105WHD thiamine biosynthesis protein ThiS AB182_23785 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) AB182_23790 ENOG4105D41 biosynthesis protein thiH AB182_23795 ENOG4106TD9 Diguanylate cyclase AB182_23805 ENOG4105VCP PTS System AB182_23820 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AB182_23825 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AB182_23835 ENOG4108VZM 50s ribosomal protein L10 AB182_23845 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) AB182_23850 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) AB182_23855 ENOG4105PM1 preprotein translocase subunit SecE AB182_23860 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) AB182_23885 ENOG4105CS9 pantothenic acid kinase AB182_23890 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase AB182_23895 ENOG4105D4A Cell wall formation (By similarity) AB182_23925 ENOG4108RR8 protoporphyrinogen oxidase AB182_23930 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) AB182_23935 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein AB182_23945 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AB182_23950 ENOG4105CHU acetyl-coa acetyltransferase AB182_23960 ENOG4107QK7 reductase AB182_23965 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) AB182_23970 ENOG4105MDZ Transcriptional activator rfaH AB182_23975 ENOG4105F8V Hydrolase, tatD family AB182_23980 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) AB182_23990 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) AB182_24000 ENOG4105JC1 sterol-binding domain protein AB182_24005 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AB182_24010 ENOG4108I5U Uridine phosphorylase AB182_24015 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) AB182_24035 ENOG4105E0C molybdate abc transporter AB182_24040 ENOG4105C4Y ABC transporter AB182_24045 ENOG4105E98 transcriptional regulator DeoR family AB182_24060 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) AB182_24065 ENOG4105DZ2 Transcriptional regulator AB182_24075 ENOG4105DQF Hydrolase AB182_24080 ENOG4108EUD Lysophospholipase AB182_24085 ENOG410829K Lysine exporter protein (Lyse ygga) AB182_24090 ENOG4105CCF Lysine exporter protein (Lyse ygga) AB182_24095 ENOG4105C9U ATP-dependent DNA helicase RecQ AB182_24100 ENOG4105HDD phospholipase AB182_24105 ENOG4108VUY thioesterase Superfamily protein AB182_24110 ENOG4105FR1 rard protein AB182_24120 ENOG4105C4R Atp-dependent dna helicase AB182_24125 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant AB182_24130 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB182_24135 ENOG4105CT0 Protein of unknown function, DUF484 AB182_24145 ENOG4105S7Z (LipO)protein AB182_24155 ENOG4107T0K Adenylate cyclase AB182_24165 ENOG41076E6 Uroporphyrinogen-III Synthase AB182_24170 ENOG4105ECF c-methyltransferase AB182_24175 ENOG410601J HemY protein AB182_24205 ENOG4105C85 amino acid AB182_24210 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family AB182_24215 ENOG4105DAD Could be involved in ECA polysaccharide chain elongation (By similarity) AB182_24225 ENOG4105EGZ biosynthesis protein AB182_24230 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AB182_24235 ENOG4108WJ1 acetyltransferase AB182_24240 ENOG4108IJ1 Dehydrogenase AB182_24245 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AB182_24250 ENOG4105SFE lipopolysaccharide biosynthesis protein AB182_24255 ENOG4105ESV Glycosyl transferase, family 4 AB182_24265 ENOG4105K63 Thioredoxin AB182_24280 ENOG4105C4R Atp-dependent dna helicase AB182_24285 ENOG4105KQ5 peptidylprolyl cis-trans isomerase AB182_24290 ENOG4105KQ5 peptidylprolyl cis-trans isomerase AB182_24310 ENOG4105EMY transcriptional regulator AB182_24325 ENOG4105C7B Threonine dehydratase AB182_24335 ENOG4105CM2 brancheD-chain amino acid aminotransferase AB182_24340 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit AB182_24350 ENOG4105C0P Mg chelatase subunit ChlI AB182_24355 ENOG4108WFC UPF0438 protein yifE AB182_24415 ENOG4108Y73 Membrane AB182_24420 ENOG4105EJ2 Transcriptional regulator AB182_24430 ENOG4105C5Q Transcriptional regulator AB182_24435 ENOG4105CH7 arginosuccinase AB182_24440 ENOG4105CAS nag kinase AB182_24445 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase AB182_24450 ENOG4105CWC Acetylornithine deacetylase AB182_24455 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) AB182_24460 ENOG4106R3P AraC family transcriptional regulator AB182_24465 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AB182_24470 ENOG4105DCT glycerol dehydrogenase AB182_24475 ENOG4105MVE transcriptional regulator AB182_24480 ENOG4105C6N Formate acetyltransferase AB182_24485 ENOG4105F1A Pyruvate formate-lyase AB182_24490 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) AB182_24495 ENOG4105CE4 GlcNAc 6-P deacetylase AB182_24500 ENOG4105SYT Methylenetetrahydrofolate reductase AB182_24505 ENOG4105CFH Aspartokinase AB182_24510 ENOG4105C28 cystathionine AB182_24515 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) AB182_24520 ENOG4107S01 Repressor protein MetJ AB182_24525 ENOG4108RS6 transposase AB182_24530 ENOG4105CT4 transporter AB182_24535 ENOG4108QGT oligogalacturonate-specific porin AB182_24545 ENOG4105C25 Primosomal protein n' AB182_24550 ENOG4105ETE Transcriptional regulator (LacI family AB182_24555 ENOG41063M6 Cell Division Protein AB182_24570 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase AB182_24575 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) AB182_24580 ENOG4105N4M Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity) AB182_24585 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) AB182_24590 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) AB182_24595 ENOG4105CBT Fructose-1,6-bisphosphatase AB182_24600 ENOG4105DP0 ferredoxin-NADP reductase AB182_24605 ENOG4108VTS Membrane AB182_24610 ENOG4105EBK exported protein AB182_24615 ENOG4105CP7 Triose-phosphate isomerase AB182_24620 ENOG41069FQ Metallo-beta-lactamase superfamily AB182_24635 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) AB182_24640 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein AB182_24645 ENOG4105CTQ phosphohexokinase AB182_24650 ENOG41076HS cation diffusion facilitator family transporter AB182_24655 ENOG4105FMW periplasmic AB182_24660 ENOG4105E3W Two component transcriptional regulator (Winged helix family AB182_24665 ENOG4105E0F Histidine kinase AB182_24670 ENOG4108RPX mosc domain containing protein AB182_24675 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB182_24685 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AB182_24690 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit AB182_24700 ENOG4105CG6 trap dicarboxylate transporter dctm subunit AB182_24705 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) AB182_24710 ENOG4107S4Z Activates expression of the rhaBAD and rhaT operons (By similarity) AB182_24715 ENOG4108QGT oligogalacturonate-specific porin AB182_24720 ENOG4105DET Rhamnulokinase AB182_24725 ENOG4105DKG l-rhamnose isomerase AB182_24730 ENOG4105C9J Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity) AB182_24735 ENOG4105D4B ABC, transporter AB182_24740 ENOG4105C2J ABC transporter AB182_24745 ENOG4105CNN ABC, transporter AB182_24750 ENOG4105F5R ABC transporter AB182_24755 ENOG4105C0A alcohol dehydrogenase AB182_24760 ENOG4105M10 Involved in the anomeric conversion of L-rhamnose (By similarity) AB182_24765 ENOG4108I5G Major Facilitator superfamily AB182_24770 ENOG4108R66 Conserved Protein AB182_24775 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB182_24780 ENOG4108RVA ribokinase AB182_24790 ENOG4108UMN azlc family AB182_24815 ENOG4105D2N Aldolase AB182_24830 ENOG4105CTQ phosphohexokinase AB182_24860 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB182_24865 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB182_24870 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein AB182_24875 ENOG4108MG3 formate dehydrogenase AB182_24880 ENOG4105CP2 von willebrand factor, type a AB182_24885 ENOG4105BZU Histidine kinase AB182_24890 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AB182_24895 ENOG4105F46 Necessary for formate dehydrogenase activity (By similarity) AB182_24915 ENOG4105SUU thioesterase domain AB182_24920 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) AB182_24930 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 AB182_24940 ENOG4105CSH Transporter AB182_24950 ENOG4105CPQ Dehydrogenase AB182_24955 ENOG4105D2M Aldolase AB182_24960 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AB182_24965 ENOG4108MGF sugar kinase AB182_24970 ENOG4105E98 transcriptional regulator DeoR family AB182_24980 ENOG4105C5F glutamine synthetase AB182_24985 ENOG4105CUX Signal transduction histidine kinase AB182_24990 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AB182_24995 ENOG4105D4P Coproporphyrinogen iii oxidase AB182_25000 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) AB182_25010 ENOG4105C2M dna polymerase I AB182_25015 ENOG4106HNH Acyl-transferase AB182_25025 ENOG4105E27 serine threonine protein kinase AB182_25030 ENOG4105PC1 Conserved Protein AB182_25035 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) AB182_25040 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b AB182_25065 ENOG4107EJG GntR family transcriptional regulator AB182_25070 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB182_25075 ENOG4105ETE Transcriptional regulator (LacI family AB182_25080 ENOG4108RVA ribokinase AB182_25085 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AB182_25090 ENOG4105CNN ABC, transporter AB182_25095 ENOG4105C2J ABC transporter AB182_25100 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) AB182_25115 ENOG4105EV2 VWA domain protein interacting with AAA ATPase AB182_25125 ENOG4108VVK transcriptional Regulator, AsnC AB182_25130 ENOG4105QTB Flavodoxin AB182_25135 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) AB182_25140 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) AB182_25145 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation AB182_25150 ENOG4105EE4 it plays a direct role in the translocation of protons across the membrane (By similarity) AB182_25155 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) AB182_25160 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) AB182_25185 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) AB182_25190 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) AB182_25195 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) AB182_25205 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) AB182_25210 ENOG4105C8U phosphate abc transporter AB182_25215 ENOG4105E2Z phosphate ABC transporter (Permease AB182_25230 ENOG4108P68 Outer membrane porin AB182_25235 ENOG4105DYC esterase AB182_25240 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 AB182_25245 ENOG4105C7N Xanthine uracil vitamin C permease AB182_25250 ENOG4108YYH Nadph-dependent fmn reductase AB182_25255 ENOG4105E8Q phosphopantetheinyl transferase AB182_25265 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) AB182_25270 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins AB182_25285 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AB182_25290 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) AB182_25295 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB182_25300 ENOG4105CC0 LysR family Transcriptional regulator AB182_25305 ENOG4105DQ4 alcohol dehydrogenase AB182_25310 ENOG410667J hydrolase AB182_25320 ENOG4105EMF GntR family transcriptional regulator AB182_25325 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 AB182_25330 ENOG4108RTU Aldolase AB182_25335 ENOG4105CXK mandelate racemase muconate lactonizing AB182_25340 ENOG4105DJB Major Facilitator Superfamily AB182_25345 ENOG4105D99 atp gtp-binding protein AB182_25350 ENOG4105R2A (LipO)protein AB182_25360 ENOG4108SHS Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent (By similarity) AB182_25365 ENOG4105D0C transport protein AB182_25370 ENOG4105FDP GntR family transcriptional regulator AB182_25375 ENOG4105CI1 PTS System AB182_25380 ENOG4105F8D glycoside hydrolase family 4 AB182_25385 ENOG4105VG5 Membrane AB182_25390 ENOG4105JP4 Inner membrane protein yidG AB182_25405 ENOG4105W8I Transcriptional regulator AB182_25410 ENOG4105E5M Multidrug resistance protein D AB182_25420 ENOG4107R3N Filamentation induced by cAMP protein fic AB182_25430 ENOG4105C7K acetolactate synthase AB182_25435 ENOG4105M71 acetolactate synthase 1 regulatory subunit AB182_25440 ENOG4107FB0 transcriptional regulator DeoR family AB182_25445 ENOG4108RVA ribokinase AB182_25450 ENOG4105EDR glucose galactose transporter AB182_25460 ENOG4108SAJ Protein of unknown function (DUF1198) AB182_25470 ENOG4108UZ3 Transporter AB182_25475 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) AB182_25480 ENOG4105VCP PTS System AB182_25485 ENOG4105CS2 ec 3.2.1.21 AB182_25490 ENOG4105CK1 PTS System AB182_25500 ENOG4105ETE Transcriptional regulator (LacI family AB182_25505 ENOG4108UMS Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity) AB182_25510 ENOG4108RCM Nitroreductase AB182_25545 ENOG4105HEI LysR family (Transcriptional regulator AB182_25550 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr AB182_25555 ENOG4105VGJ Virulence-associated protein AB182_25560 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A AB182_25565 ENOG4105EJC lysr family transcriptional regulator AB182_25575 ENOG4105ERH Fumarylacetoacetate hydrolase AB182_25580 ENOG4108TFY Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AB182_25585 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AB182_25595 ENOG4105DRP amino acid AbC transporter AB182_25605 ENOG4105EAB amino acid AbC transporter AB182_25630 ENOG4105VT3 DNA binding domain protein, excisionase family AB182_25640 ENOG4105C6Z Gluconate AB182_25645 ENOG4105C01 Dihydroxy-acid dehydratase AB182_25650 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB182_25655 ENOG4106P37 HTH-type transcriptional regulator YjhI AB182_25665 ENOG4108Q9V regulatoR AB182_25670 ENOG4108ZI2 Fimbrial protein AB182_25675 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) AB182_25680 ENOG4105CW0 outer membrane usher protein AB182_25685 ENOG4108AF8 Chaperone AB182_25690 ENOG4108WDE Fimbrial protein AB182_25700 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction AB182_25710 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction AB182_25725 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction AB182_25790 ENOG4105CT4 transporter AB182_25795 ENOG4105CJQ hydrolase, family 31 AB182_25805 ENOG4105ETD TRANSCRIPTIONal AB182_25810 ENOG4105DM4 PTS System AB182_25815 ENOG4108YRF PTS System AB182_25820 ENOG4105DM4 PTS System AB182_25825 ENOG4105D2N Aldolase AB182_25830 ENOG4105D2N Aldolase AB182_25835 ENOG4105DKQ ROK family AB182_25845 ENOG4105JV1 AsmA family AB182_25850 ENOG4105C2W permease AB182_25860 ENOG4105CB5 ATP-dependent DNA helicase recG AB182_25865 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase AB182_25870 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AB182_25875 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) AB182_25915 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) AB182_25940 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB182_25945 ENOG4105W5Q DNA repair protein (RadC AB182_25960 ENOG4105ZUU Transcriptional regulator AB182_26005 ENOG4105DSJ YicC domain protein AB182_26025 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) AB182_26030 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase AB182_26040 ENOG4105KDC 50s ribosomal protein l28 AB182_26045 ENOG4105W0E 50S ribosomal protein L33 AB182_26050 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) AB182_26055 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) AB182_26060 ENOG4106WTF Glycosyl transferase, family 2 AB182_26065 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase AB182_26070 ENOG4105K64 Glycosyl transferase, family 2 AB182_26075 ENOG4105CPK Glycosyl transferase (Group 1 AB182_26085 ENOG4105DKP glycosyl transferase, family 9 AB182_26110 ENOG4105D16 lipopolysaccharide heptosyltransferase i AB182_26115 ENOG4105XA0 heptosyltransferase ii AB182_26125 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AB182_26130 ENOG4105CPQ Dehydrogenase AB182_26135 ENOG4106WTF Glycosyl transferase, family 2 AB182_26140 ENOG4105PXI polysaccharide deacetylase AB182_26145 ENOG41063SB peptidase AB182_26150 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) AB182_26155 ENOG4107YZP Rhodanese domain protein AB182_26160 ENOG4105VW4 glutaredoxin 3 AB182_26175 ENOG4105D7W serine acetyltransferase AB182_26180 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) AB182_26185 ENOG4105DMF Dehydrogenase AB182_26190 ENOG41073TP transcriptional regulator AB182_26195 ENOG4108YYI Protein of unknown function (DUF2810) AB182_26200 ENOG41060ND LF82 chromosome, complete sequence AB182_26205 ENOG4105E61 Mannitol repressor protein AB182_26215 ENOG4105CTS PTS system mannitol-specific AB182_26220 ENOG4108U78 Glutathione S-transferase AB182_26225 ENOG4105C1Y Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity) AB182_26230 ENOG4105EM7 Selenocysteine-specific translation elongation factor AB182_26245 ENOG4105C1J atp-dependent rna helicase AB182_26255 ENOG4105CT4 transporter AB182_26265 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase AB182_26270 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase AB182_26275 ENOG4105H6Q decarboxylase AB182_26280 ENOG4105CMG Carbohydrate kinase AB182_26290 ENOG4108M5W AB182_26295 ENOG4108R66 Conserved Protein AB182_26300 ENOG4105DG4 malate L-lactate dehydrogenase AB182_26315 ENOG4105CNN ABC, transporter AB182_26320 ENOG4105C2J ABC transporter AB182_26325 ENOG4105J4Q Transcriptional regulator AB182_26330 ENOG4108XIB electron transport protein ysaA AB182_26335 ENOG4105JKW Valine--pyruvate aminotransferase AB182_26340 ENOG4107T9C Alpha amylase catalytic region AB182_26345 ENOG4108UR8 BAX protein AB182_26350 ENOG4105T16 Transcriptional regulator (AraC family) AB182_26355 ENOG4107RNG ABC transporter AB182_26360 ENOG4105C2J ABC transporter AB182_26365 ENOG4105DFW ABC transporter AB182_26370 ENOG4105C93 Xylose Isomerase AB182_26375 ENOG4105CMG Carbohydrate kinase AB182_26390 ENOG4108Z12 YiaAB two helix domain-containing protein AB182_26395 ENOG4105MEV Acyl-transferase AB182_26415 ENOG4107R5R arsenical pump membrane protein AB182_26425 ENOG4105MVF Transcriptional regulator AB182_26430 ENOG4106JH6 (LipO)protein AB182_26445 ENOG4108KQ5 Integrase catalytic subunit AB182_26450 ENOG4105D7K pfkb domain protein AB182_26460 ENOG4108M60 Transcriptional regulator AB182_26465 ENOG4107QY8 reductase AB182_26470 ENOG4105HNP -acetyltransferase AB182_26475 ENOG4108R3E Dna-3-methyladenine glycosylase i AB182_26480 ENOG4105EAX Putative lipase AB182_26485 ENOG4105FCD Major Facilitator AB182_26490 ENOG4108ZHJ Organic hydroperoxide resistance protein AB182_26495 ENOG4105DIJ Phosphoethanolamine transferase AB182_26510 ENOG4105DEF Extracellular solute-binding protein, family 5 AB182_26515 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AB182_26520 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB182_26525 ENOG4105C3U ABC transporter AB182_26530 ENOG4108JQ7 (ABC) transporter AB182_26545 ENOG4105C5B carbamate kinase AB182_26550 ENOG4107REC cytoplasmic protein AB182_26555 ENOG4107R1Q Membrane protein FdrA AB182_26560 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) AB182_26570 ENOG4107653 Transcriptional regulator AB182_26580 ENOG4105UTS cellulose synthase operon protein YhjQ AB182_26590 ENOG4107EEX Cellulose synthase regulator protein AB182_26595 ENOG4105EJG cellulose synthase AB182_26610 ENOG4105D1V cellulose synthase operon protein YhjU AB182_26615 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT AB182_26625 ENOG410661M cytoplasmic protein AB182_26630 ENOG4105UTS cellulose synthase operon protein YhjQ AB182_26635 ENOG4107QZ7 Cellulose synthase catalytic subunit AB182_26640 ENOG4107EEX Cellulose synthase regulator protein AB182_26645 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) AB182_26650 ENOG4105EJG cellulose synthase AB182_26655 ENOG4105BZU Histidine kinase AB182_26660 ENOG4105CK2 sodium dicarboxylate symporter AB182_26665 ENOG4105CS0 peptidase AB182_26670 ENOG4107SS6 2-dehydro-3-deoxygluconokinase AB182_26675 ENOG4105CMB EAL domain-containing protein AB182_26680 ENOG41066T0 asmA family AB182_26685 ENOG4105CSH Transporter AB182_26690 ENOG4107H3J ribonuclease AB182_26695 ENOG4105CBN LysR family transcriptional regulator AB182_26700 ENOG4105CAN Short-chain dehydrogenase reductase Sdr AB182_26705 ENOG4108YDI single-species biofilm formation on inanimate substrate AB182_26710 ENOG41068WN AB182_26725 ENOG4106NZI LysR family Transcriptional regulator AB182_26740 ENOG4105DWY Agmatine deiminase AB182_26755 ENOG4108Z3N Transcriptional regulator AB182_26760 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) AB182_26765 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AB182_26790 ENOG4105C8Q Methyl-accepting chemotaxis AB182_26800 ENOG4105DC8 reductase AB182_26805 ENOG4105D6S protein involved in catabolism of external DNA AB182_26810 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase AB182_26820 ENOG4105DGW oligopeptidase A AB182_26825 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) AB182_26830 ENOG4108M6U Universal stress protein A AB182_26835 ENOG4108V6B universal stress protein B AB182_26840 ENOG4105CJ3 phosphate transporter AB182_26845 ENOG4105CBX hi0933 family AB182_26860 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component AB182_26865 ENOG4105BZU Histidine kinase AB182_26910 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AB182_26930 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family AB182_26935 ENOG4105CPQ Dehydrogenase AB182_26940 ENOG4105CHR reductase AB182_26945 ENOG4105C6Z Gluconate AB182_26950 ENOG4105K2J Transcriptional regulator AB182_26955 ENOG4105C8Q Methyl-accepting chemotaxis AB182_26970 ENOG4105EWI Short-chain dehydrogenase reductase Sdr AB182_26980 ENOG4105MRR Transcriptional regulator (By similarity) AB182_26985 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) AB182_26990 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) AB182_26995 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB182_27000 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AB182_27005 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein AB182_27010 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein AB182_27015 ENOG4108W0P ABC transporter AB182_27020 ENOG4105EHG Permease protein AB182_27025 ENOG4105S10 periplasmic binding protein AB182_27035 ENOG4105PY6 Phenolic acid decarboxylase AB182_27040 ENOG4105DSF transport protein AB182_27045 ENOG4105F9N Major Facilitator Superfamily AB182_27050 ENOG4108W1V Lipoprotein AB182_27055 ENOG4105EX9 Membrane AB182_27060 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) AB182_27065 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit AB182_27075 ENOG4105CG6 trap dicarboxylate transporter dctm subunit AB182_27085 ENOG4107FS9 Membrane AB182_27090 ENOG4105MG3 Membrane AB182_27095 ENOG4106H78 methyltransferase AB182_27100 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) AB182_27105 ENOG4105CAK Cell division ATP-binding protein ftsE AB182_27110 ENOG4105CRP Part of the ABC transporter FtsEX involved in AB182_27115 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AB182_27125 ENOG4108JPW Aminotransferase AB182_27130 ENOG4105CP9 extracellular ligand-binding receptor AB182_27135 ENOG4105U59 -acetyltransferase AB182_27140 ENOG4105CP9 extracellular ligand-binding receptor AB182_27145 ENOG4105C32 Amino acid ABC transporter (Permease) AB182_27150 ENOG4105CF8 branched-chain amino acid ABC transporter, permease AB182_27155 ENOG4105C0Z ABC transporter AB182_27160 ENOG4108IV0 ABC, transporter AB182_27165 ENOG4105BZ7 extracellular solute-binding protein family 1 AB182_27170 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component AB182_27185 ENOG4107T6V glycerophosphoryl diester phosphodiesterase AB182_27190 ENOG4105WC8 Conserved Protein AB182_27195 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) AB182_27225 ENOG4105WCN acetyltransferase AB182_27235 ENOG4105D9R oxidoreductase AB182_27240 ENOG4105C2I pirin domain protein AB182_27245 ENOG4105DIQ Transcriptional regulator AB182_27250 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family AB182_27255 ENOG4105C6Z Gluconate AB182_27260 ENOG41076UM multiple antibiotic resistance (MarC)-related protein AB182_27265 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AB182_27275 ENOG4108ESZ Glycogen debranching enzyme AB182_27285 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) AB182_27290 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) AB182_27295 ENOG4105C6V Glycerol-3-phosphate dehydrogenase AB182_27300 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) AB182_27310 ENOG4105E98 transcriptional regulator DeoR family AB182_27315 ENOG41061ZR Transcriptional regulator AB182_27325 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) AB182_27330 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) AB182_27335 ENOG4105C6Z Gluconate AB182_27340 ENOG4107RUK Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity) AB182_27345 ENOG4105MJ2 Competence protein AB182_27365 ENOG4105CE1 Ferrous iron transport protein b AB182_27370 ENOG4105XFK Ferrous iron transport protein A AB182_27375 ENOG4105BZM domain protein AB182_27380 ENOG4108RRZ Transcription elongation factor GreB AB182_27385 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AB182_27390 ENOG4105E0F Histidine kinase AB182_27395 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase AB182_27405 ENOG4105VEJ Heat shock protein AB182_27410 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 AB182_27420 ENOG4107RK2 ADP-ribose diphosphatase NudE AB182_27425 ENOG4108JQC penicillin-binding protein 1A AB182_27435 ENOG41065NF Fimbrial assembly family protein AB182_27450 ENOG4105E4G Type IV pilus AB182_27455 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) AB182_27460 ENOG4105D49 3-dehydroquinate synthase AB182_27465 ENOG4105EGB membrane protein DamX AB182_27470 ENOG4105DFE Dna adenine methylase AB182_27475 ENOG4105DJV ribulose-phosphate 3-epimerase AB182_27485 ENOG4105C31 Tryptophanyl-tRNA synthetase AB182_27490 ENOG4105FDP GntR family transcriptional regulator AB182_27495 ENOG4108KPW sugar kinase AB182_27500 ENOG4107Y0V Not clear, may be involved in an isomerization step AB182_27505 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine AB182_27510 ENOG4107QHQ amino acid AB182_27515 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AB182_27520 ENOG4107V9H nitrite transporter AB182_27525 ENOG4105WZK nitrite reductase NADPH small subunit AB182_27530 ENOG4107QZF nitrite reductase NADPH large subunit AB182_27535 ENOG4105DZC cytosine deaminase AB182_27540 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) AB182_27545 ENOG4105MZU cell filamentation protein AB182_27550 ENOG4105DDQ anthranilate synthase AB182_27555 ENOG4105C8Y Acetylornithine aminotransferase AB182_27560 ENOG410613R integral membrane protein, YccS YhfK family AB182_27570 ENOG4108UKZ OsmC family AB182_27575 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) AB182_27585 ENOG4105DNZ Alpha Beta Hydrolase AB182_27595 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AB182_27630 ENOG4107TT2 Auxin Efflux Carrier AB182_27635 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase AB182_27640 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AB182_27645 ENOG4108K70 Transcriptional regulator AB182_27650 ENOG4105C5H ABC transporter AB182_27655 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein AB182_27660 ENOG4105CKD glutathione-regulated potassium-efflux system protein AB182_27665 ENOG4105VKU nucleicacid-binding protein AB182_27670 ENOG4108YZY peptidylprolyl cis-trans isomerase AB182_27675 ENOG4105VRX Protein slyX homolog AB182_27680 ENOG4108V1T peptidylprolyl cis-trans isomerase AB182_27685 ENOG4105WWK YheO domain protein AB182_27695 ENOG4108ZKU Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) AB182_27700 ENOG4105YKK Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) AB182_27710 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) AB182_27715 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) AB182_27720 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) AB182_27725 ENOG4105W53 bacterioferritin-associated ferredoxin AB182_27730 ENOG4108UQY Iron-storage protein AB182_27750 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) AB182_27765 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) AB182_27775 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) AB182_27780 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) AB182_27785 ENOG41083MP 50s ribosomal protein l29 AB182_27790 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal AB182_27795 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) AB182_27800 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) AB182_27815 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) AB182_27820 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) AB182_27830 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) AB182_27835 ENOG4105VPB 50S ribosomal protein L30 AB182_27845 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AB182_27850 ENOG41067V7 50S ribosomal protein L36 AB182_27860 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) AB182_27865 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) AB182_27870 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AB182_27875 ENOG4108ZT0 50S ribosomal protein l17 AB182_27880 ENOG4105VTS DnaJ-like, subfamily C AB182_27885 ENOG4105W1Y Transcriptional regulator AB182_27890 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system AB182_27900 ENOG4105C1A potassium transporter peripheral membrane AB182_27905 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B AB182_27915 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AB182_27920 ENOG4105C79 DNA protecting protein DprA AB182_27935 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) AB182_27945 ENOG4105SG3 Protein of unknown function (DUF1488) AB182_27950 ENOG4108Z0R Transferase AB182_27985 ENOG4105CDA abc transporter atp-binding protein AB182_27990 ENOG4105DRP amino acid AbC transporter AB182_27995 ENOG4105EZ7 amino acid ABC transporter AB182_28005 ENOG4105CMM transposase AB182_28015 ENOG4105BZU Histidine kinase AB182_28020 ENOG41061ME transport protein AB182_28025 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) AB182_28030 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AB182_28040 ENOG4108IA2 Sodium pantothenate symporter AB182_28045 ENOG4105RG0 Membrane AB182_28050 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AB182_28055 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein AB182_28060 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) AB182_28075 ENOG4105DFF Rod shape-determining protein mreb AB182_28080 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) AB182_28085 ENOG4105VQ7 Rod shape-determining protein MreD AB182_28095 ENOG4105C03 ribonuclease AB182_28100 ENOG4105QD6 exported protein AB182_28105 ENOG4105D1U peptidase U62 modulator of DNA gyrase AB182_28110 ENOG4105CR8 Transcriptional regulator AB182_28115 ENOG4105ZQC membrane protein AaeX AB182_28125 ENOG4107Z11 Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity) AB182_28135 ENOG4105UNR (Barnase) inhibitor AB182_28140 ENOG4105RID UPF0379 protein yhcN AB182_28145 ENOG4105RID UPF0379 protein yhcN AB182_28150 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) AB182_28160 ENOG4105C0H protease AB182_28165 ENOG4105C0H protease AB182_28170 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III AB182_28175 ENOG4105D6Z AFG1 family ATPase AB182_28185 ENOG4108UJD 30S ribosomal protein S9 AB182_28190 ENOG4107MKT Stringent starvation protein a AB182_28195 ENOG4105KB2 stringent starvation protein b AB182_28220 ENOG4105DJB Major Facilitator Superfamily AB182_28225 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) AB182_28230 ENOG4108QBF Transcriptional regulator AB182_28240 ENOG4105JHE Major Facilitator Superfamily AB182_28255 ENOG4108R66 Conserved Protein AB182_28260 ENOG4108RS6 transposase AB182_28265 ENOG4105BZ8 glutamate synthase AB182_28270 ENOG4105CBC glutamate synthase AB182_28275 ENOG4105N5T Radical SAM Protein AB182_28280 ENOG4105BZU Histidine kinase AB182_28285 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain AB182_28290 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase AB182_28295 ENOG41080Z8 PHOSPHOCARRIER protein AB182_28300 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) AB182_28305 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN AB182_28310 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA AB182_28315 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AB182_28320 ENOG4108IUZ ABC transporter AB182_28325 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA AB182_28330 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) AB182_28340 ENOG4105C2X Arabinose 5-phosphate isomerase AB182_28345 ENOG4105FEU K -dependent Na -Ca exchanger AB182_28350 ENOG4105DHJ ABC, transporter AB182_28355 ENOG4105CY3 ABC transporter, permease AB182_28360 ENOG4107PE3 Mammalian cell entry related domain protein AB182_28365 ENOG4105E3I toluene tolerance AB182_28370 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane AB182_28375 ENOG4105VFK BolA family AB182_28380 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) AB182_28385 ENOG4105HVQ Regulatory factor of maltose metabolism AB182_28390 ENOG4105EAH synthase AB182_28400 ENOG4105K46 50S ribosomal protein l27 AB182_28405 ENOG4105QYV Membrane AB182_28410 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control AB182_28415 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase AB182_28420 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) AB182_28425 ENOG4105HBR Rna-binding protein AB182_28430 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) AB182_28435 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AB182_28440 ENOG4105EEI dihydropteroate synthase AB182_28460 ENOG4105CDH Citrulline--aspartate ligase AB182_28470 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) AB182_28475 ENOG4105CHV Transcription elongation factor NusA AB182_28490 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) AB182_28495 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) AB182_28500 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) AB182_28510 ENOG4105C1J atp-dependent rna helicase AB182_28515 ENOG4105CIC tryptophan-specific transport protein AB182_28520 ENOG4105DEN Luciferase family AB182_28525 ENOG4106RZ4 Peptidase U32 AB182_28530 ENOG4105CFP Peptidase U32 AB182_28535 ENOG4105XPQ lipid carrier protein AB182_28540 ENOG4108YYD acetyltransferase AB182_28555 ENOG4107R7Y intracellular protease Pfpi family AB182_28560 ENOG4105K4T epimerase AB182_28565 ENOG4107S21 permease AB182_28570 ENOG4105W4M Transport-associated protein AB182_28575 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) AB182_28585 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) AB182_28590 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) AB182_28595 ENOG4106HBN Galactosamine-6-phosphate isomerase AB182_28600 ENOG4105F3R pts system mannose fructose sorbose family iid AB182_28605 ENOG4105ETZ PTS System AB182_28610 ENOG4108UZY PTS System AB182_28620 ENOG4105E70 isomerase AB182_28625 ENOG4108YTN IIa component AB182_28630 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of AB182_28635 ENOG4105E98 transcriptional regulator DeoR family AB182_28640 ENOG4105CTX dehydratase AB182_28645 ENOG4105DJB Major Facilitator Superfamily AB182_28650 ENOG4105CNV Aldolase AB182_28655 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AB182_28660 ENOG4105BZW Glycerate kinase AB182_28665 ENOG4108CNN domain protein AB182_28670 ENOG4105CWB LysR family transcriptional Regulator AB182_28675 ENOG4105KAF membrAne AB182_28680 ENOG4105CHF Glutathione S-transferase AB182_28685 ENOG4108VBZ doxx family AB182_28690 ENOG4105YJD AB182_28695 ENOG41090KG Inner membrane protein YqjE AB182_28700 ENOG4105NE1 Conserved Protein AB182_28705 ENOG4105WAY exported protein AB182_28710 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) AB182_28715 ENOG4106W5V Membrane AB182_28720 ENOG4107YCY Transcriptional regulator AB182_28725 ENOG4105DPW Major facilitator superfamily MFS_1 AB182_28735 ENOG4105CTX dehydratase AB182_28740 ENOG4105P66 Membrane AB182_28745 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) AB182_28750 ENOG4105DU1 integral membrane protein, terc AB182_28755 ENOG4105EE0 oxidoreductase AB182_28765 ENOG4105D01 (LipO)protein AB182_28775 ENOG4108UMI ABC transporter, permease AB182_28780 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) AB182_28795 ENOG4105CGF Aromatic amino acid aminotransferase AB182_28805 ENOG4105F7P transcriptional regulator AsnC family AB182_28810 ENOG4105C85 amino acid AB182_28815 ENOG4105DKT Transcriptional regulator AB182_28830 ENOG4105G63 Type III effector Hrp-dependent AB182_28835 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) AB182_28840 ENOG4105VI0 Pts system, glucitol sorbitol-specific AB182_28845 ENOG4108YZG isomerase AB182_28850 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AB182_28855 ENOG4105CV1 Transketolase (EC 2.2.1.1) AB182_28860 ENOG4105MVE transcriptional regulator AB182_28870 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB182_28875 ENOG4108VKG metal-dependent hydrolase AB182_28880 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) AB182_28885 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB182_28890 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) AB182_28895 ENOG4105DKT Transcriptional regulator AB182_28900 ENOG4105C2J ABC transporter AB182_28905 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane AB182_28910 ENOG4105F5R ABC transporter AB182_28915 ENOG4105D4B ABC, transporter AB182_28920 ENOG41061GT Aldolase AB182_28925 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound AB182_28935 ENOG4105C8Y Acetylornithine aminotransferase AB182_28940 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AB182_28945 ENOG4105C8Q Methyl-accepting chemotaxis AB182_28950 ENOG4105NTW Transcriptional regulator AB182_28955 ENOG4105Q26 Siderophore-interacting protein AB182_28970 ENOG4105DDV Transcriptional regulator (LacI family AB182_28990 ENOG4105V2F Uncharacterized protein yoac AB182_29025 ENOG4105CMM transposase AB182_29035 ENOG41090SZ ABC-2 type transporter AB182_29050 ENOG4108ZSJ is1 orf2 AB182_29070 ENOG41084CK capsule polysaccharide AB182_29075 ENOG4105E12 capsule polysaccharide AB182_29080 ENOG4107V1M polysaccharide export protein AB182_29085 ENOG4105ECX polysaccharide export AB182_29090 ENOG4105C2X Arabinose 5-phosphate isomerase AB182_29095 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AB182_29100 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) AB182_29105 ENOG4105VCC 30S ribosomal protein S21 AB182_29115 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) AB182_29120 ENOG4107ZVW dihydroneopterin aldolase AB182_29125 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) AB182_29130 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate AB182_29135 ENOG4106MWK domain protein AB182_29140 ENOG4105I7R Adenylate cyclase AB182_29145 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) AB182_29155 ENOG4107S78 Band 7 protein AB182_29160 ENOG4105PV3 Inner membrane protein yqiJ AB182_29165 ENOG4105W0Z cytoplasmic protein AB182_29185 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b AB182_29190 ENOG4106032 Glutathionylspermidine synthase AB182_29195 ENOG4105F1G UPF0441 protein AB182_29200 ENOG4105DFG type I secretion outer membrane protein AB182_29205 ENOG41087AY ADP-Ribose pyrophosphatase AB182_29210 ENOG4108SX3 cytoplasmic protein AB182_29215 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) AB182_29220 ENOG4105IPS esterase AB182_29225 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB182_29235 ENOG4105D2H Uronic isomerase AB182_29240 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) AB182_29245 ENOG4108YS1 cytoplasmic protein AB182_29250 ENOG4105YP6 Domain of unknown function (DUF1869) AB182_29255 ENOG4105VRH Antibiotic biosynthesis monooxygenase AB182_29260 ENOG4105NF4 modulator of drug activity AB182_29270 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB182_29275 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase AB182_29280 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) AB182_29300 ENOG4107QPK )-transporter AB182_29305 ENOG4105CV8 reductase AB182_29310 ENOG4108I6A alcohol dehydrogenase AB182_29315 ENOG4105CF7 AraC family transcriptional regulator AB182_29320 ENOG4108K81 inner membrane protein YghB AB182_29325 ENOG4105C28 cystathionine AB182_29330 ENOG4105CWK Biopolymer transport protein, ExbB AB182_29335 ENOG4108ZZF transport protein (ExbD) AB182_29355 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) AB182_29365 ENOG4105CPC Aldo Keto reductase AB182_29370 ENOG4105C8Q Methyl-accepting chemotaxis AB182_29375 ENOG410900S Protein of unknown function (DUF2623) AB182_29380 ENOG4105E3S small subunit AB182_29385 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein AB182_29390 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit AB182_29395 ENOG4105DPX Hydrogenase, large subunit AB182_29400 ENOG4108USZ hydrogenase AB182_29405 ENOG4108WGS hydrogenase 2-specific chaperone AB182_29410 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) AB182_29415 ENOG41082MF Hydrogenase assembly chaperone hypC hupF AB182_29420 ENOG4107EDW L-fucose operon activator AB182_29425 ENOG4105BZU Histidine kinase AB182_29430 ENOG4105CYM Glutathione S-transferase AB182_29440 ENOG4105D7K pfkb domain protein AB182_29450 ENOG4108M0B Sucrose porin AB182_29475 ENOG4105DYS nad(p)h dehydrogenase (quinone) AB182_29505 ENOG4108ZSJ is1 orf2 AB182_29520 ENOG4105D58 Diguanylate phosphodiesterase AB182_29525 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A AB182_29550 ENOG4105EJC lysr family transcriptional regulator AB182_29560 ENOG4105ERH Fumarylacetoacetate hydrolase AB182_29565 ENOG4108TFY Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AB182_29570 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AB182_29575 ENOG4105D94 Major Facilitator Superfamily AB182_29680 ENOG4108UQV Membrane