locus-tag	class	description
CS374_00005	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CS374_00020	ENOG4105C3M	thioredoxin reductase
CS374_00060	ENOG4105JNK	Glycosyl transferase (Group 1
CS374_00075	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CS374_00085	ENOG4108IQE	Amp-dependent synthetase and ligase
CS374_00095	ENOG4105CG5	Glycosyl transferase (Group 1
CS374_00105	ENOG4108I6A	alcohol dehydrogenase
CS374_00125	ENOG4105FE9	pseudouridine synthase
CS374_00130	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CS374_00135	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CS374_00140	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CS374_00145	ENOG4108WBT	adenosyltransferase
CS374_00150	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CS374_00160	ENOG4105EAC	phosphoserine phosphatase
CS374_00165	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CS374_00170	ENOG4107QR9	Iron-sulfur cluster binding protein
CS374_00175	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
CS374_00185	ENOG4105UYK	outer membrane protein a
CS374_00190	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CS374_00195	ENOG4107XVI	synthase
CS374_00210	ENOG4105KNI	merR family transcriptional Regulator
CS374_00230	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CS374_00255	ENOG4105CE1	Ferrous iron transport protein b
CS374_00270	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
CS374_00275	ENOG4108I6E	Sulfatase
CS374_00290	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CS374_00325	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CS374_00365	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CS374_00375	ENOG4105CYC	Transferase
CS374_00380	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CS374_00385	ENOG4105CZV	ABC transporter
CS374_00400	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
CS374_00455	ENOG4105ECP	epimerase
CS374_00465	ENOG4105C22	threonyL-tRNA synthetase
CS374_00470	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CS374_00475	ENOG4105VJV	50s ribosomal protein L35
CS374_00480	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CS374_00515	ENOG4105CFU	surface antigen
CS374_00520	ENOG4105E2X	shikimate dehydrogenase
CS374_00525	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CS374_00530	ENOG4107QWK	SAICAR synthetase
CS374_00535	ENOG4105C9A	Phoh family
CS374_00555	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CS374_00585	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
CS374_00600	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CS374_00610	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CS374_00625	ENOG4107S2Z	UPF0761 membrane protein
CS374_00630	ENOG4105DTN	riboflavin biosynthesis protein ribF
CS374_00650	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CS374_00655	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CS374_00660	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CS374_00665	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CS374_00685	ENOG4108IUX	(ABC) transporter
CS374_00690	ENOG4105RHA	ABC transporter, permease
CS374_00715	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CS374_00725	ENOG4105C7N	Xanthine uracil vitamin C permease
CS374_00730	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CS374_00735	ENOG4105CCT	upf0313 protein
CS374_00740	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CS374_00765	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CS374_00770	ENOG4105K8N	protein family UPF0079, ATPase
CS374_00780	ENOG4107T8J	thymidine kinase
CS374_00785	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
CS374_00790	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CS374_00795	ENOG4105D60	lipoprotein releasing system transmembrane protein
CS374_00800	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CS374_00805	ENOG4105CD3	dihydroorotase
CS374_00850	ENOG4105CEM	UPF0597 protein
CS374_00870	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CS374_00885	ENOG4105CWX	Alpha-1,2-mannosidase
CS374_00895	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CS374_00905	ENOG4105D78	K07001 NTE family protein
CS374_00910	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CS374_00915	ENOG4105CNT	hydrolase family 2
CS374_00925	ENOG4105W5Q	DNA repair protein (RadC
CS374_00930	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CS374_00935	ENOG4105G6Z	alkaline phosphatase
CS374_00940	ENOG4105DC7	peptidase M24
CS374_00950	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CS374_00970	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CS374_00975	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CS374_00990	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CS374_01085	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CS374_01260	ENOG4107QTH	restriction modification system DNA specificity domain
CS374_01360	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CS374_01375	ENOG4105CNA	YD repeat protein
CS374_01450	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CS374_01470	ENOG4108Q5F	Tetr family transcriptional regulator
CS374_01505	ENOG4105DIA	mandelate racemase muconate lactonizing
CS374_01510	ENOG4108IPT	Naphthoate synthase
CS374_01515	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CS374_01520	ENOG4105E4F	Isochorismate synthase
CS374_01535	ENOG4105E4P	ATPase (AAA
CS374_01585	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CS374_01590	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CS374_01595	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CS374_01600	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CS374_01605	ENOG4105CFP	Peptidase U32
CS374_01615	ENOG4105D1Q	UPF0246 protein
CS374_01620	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CS374_01635	ENOG4105IUR	peptidase C10
CS374_01650	ENOG4105D05	Receptor
CS374_01655	ENOG4105CTK	cobaltochelatase, cobn subunit
CS374_01680	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CS374_01695	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CS374_01700	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
CS374_01715	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CS374_01735	ENOG4108VCT	Sulfite exporter TauE/SafE
CS374_01740	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
CS374_01755	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
CS374_01770	ENOG4108IYU	L-aspartate oxidase
CS374_01775	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CS374_01780	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CS374_01785	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CS374_01825	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
CS374_01830	ENOG4105C8B	TIGR00159 family
CS374_01835	ENOG4105EEI	dihydropteroate synthase
CS374_01860	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CS374_01890	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CS374_01895	ENOG4105SCY	DNAK suppressor
CS374_01900	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CS374_01915	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CS374_01925	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CS374_01950	ENOG4105D9Q	decarboxylase (Beta subunit)
CS374_01955	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
CS374_01970	ENOG4107QX3	carboxylase
CS374_01975	ENOG4108ZVT	methylmalonyl-coA epimerase
CS374_02000	ENOG4105C59	p-type ATPase
CS374_02005	ENOG4105C59	p-type ATPase
CS374_02010	ENOG4105KJF	protein tyrosine phosphatase
CS374_02015	ENOG4107R73	Mate efflux family protein
CS374_02020	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CS374_02025	ENOG4105CNU	cell division protein FtsK
CS374_02040	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CS374_02045	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CS374_02090	ENOG4105DF5	DNA topoisomerase IV, subunit A
CS374_02105	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CS374_02110	ENOG4105HSA	Protein of unknown function (DUF452)
CS374_02120	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CS374_02125	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CS374_02160	ENOG4105CMN	Methylmalonyl-coA mutase
CS374_02165	ENOG4105D5P	Methylmalonyl-coA mutase
CS374_02180	ENOG4105EMN	RNA polymerase sigma factor
CS374_02190	ENOG4105C19	ABC transporter
CS374_02195	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CS374_02280	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
CS374_02285	ENOG4105BZA	Phosphoglycerate kinase
CS374_02305	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CS374_02330	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CS374_02335	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CS374_02345	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CS374_02355	ENOG4105HHA	aminodeoxychorismate lyase
CS374_02380	ENOG4108Z86	Glutamine amidotransferase
CS374_02385	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CS374_02390	ENOG4108IY2	MazG family
CS374_02400	ENOG4105C34	Pseudouridine synthase
CS374_02440	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CS374_02455	ENOG4105BZ1	(ABC) transporter
CS374_02465	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CS374_02480	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
CS374_02490	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CS374_02495	ENOG4105CEV	competence damage-inducible protein
CS374_02510	ENOG4107Y2X	deaminase
CS374_02515	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CS374_02530	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CS374_02535	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CS374_02550	ENOG4105E09	nadh pyrophosphatase
CS374_02555	ENOG4105DKQ	ROK family
CS374_02565	ENOG4107R33	ppx gppa phosphatase
CS374_02570	ENOG4108IJ0	Aspartate ammonia-lyase
CS374_02575	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CS374_02590	ENOG4105NGQ	Thioredoxin
CS374_02605	ENOG4105C37	(CBS) domain
CS374_02610	ENOG4108UUM	single-stranded DNA-binding protein
CS374_02615	ENOG4105C5Q	Transcriptional regulator
CS374_02620	ENOG4105CGK	Exodeoxyribonuclease III
CS374_02625	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CS374_02630	ENOG4105C75	arginyL-tRNA synthetase
CS374_02640	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CS374_02665	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CS374_02670	ENOG4105CHV	Transcription elongation factor NusA
CS374_02675	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
CS374_02685	ENOG4107QSA	Oxaloacetate decarboxylase
CS374_02720	ENOG4105PAD	Hydrolase
CS374_02730	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CS374_02740	ENOG4105CN1	protease
CS374_02760	ENOG4105EHZ	conserved protein UCP016719
CS374_02765	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CS374_02780	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CS374_02790	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
CS374_02850	ENOG4105E4R	Precorrin-3B C17-methyltransferase
CS374_02855	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
CS374_02860	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
CS374_02865	ENOG4107UA7	cobalamin biosynthesis protein CbiD
CS374_02870	ENOG4105TMB	Formate nitrite transporter
CS374_02880	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CS374_02900	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CS374_02905	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CS374_02910	ENOG4105F8V	Hydrolase, tatD family
CS374_02915	ENOG4105KAF	membrAne
CS374_02930	ENOG4107RAN	Peptidase, M16
CS374_02935	ENOG4108RAC	Rubrerythrin
CS374_02945	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
CS374_02955	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CS374_02980	ENOG4105C27	TonB-dependent Receptor Plug
CS374_02995	ENOG4108YG4	
CS374_03000	ENOG4106JK2	
CS374_03005	ENOG4106HJD	
CS374_03010	ENOG4106RSZ	Pfam:DUF1812
CS374_03025	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CS374_03040	ENOG4105CGH	5'-nucleotidase
CS374_03045	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CS374_03260	ENOG4108RZE	Tetr family transcriptional regulator
CS374_03320	ENOG4105VTR	Integrase
CS374_03325	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CS374_03330	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CS374_03335	ENOG4105VEJ	Heat shock protein
CS374_03345	ENOG4105CTQ	phosphohexokinase
CS374_03350	ENOG4105EMN	RNA polymerase sigma factor
CS374_03360	ENOG4105C9K	Endothelin-converting enzyme 1
CS374_03370	ENOG4105MJ2	Competence protein
CS374_03375	ENOG4105Y3E	Modulates RecA activity (By similarity)
CS374_03380	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CS374_03385	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CS374_03390	ENOG4105C9M	aspartyl-trna synthetase
CS374_03400	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CS374_03405	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CS374_03435	ENOG4105DWY	Agmatine deiminase
CS374_03445	ENOG4107QJE	Chromosome Partitioning Protein
CS374_03450	ENOG4105FA0	parb-like partition protein
CS374_03465	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CS374_03470	ENOG4105CIN	aminoacyl-histidine dipeptidase
CS374_03480	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CS374_03485	ENOG4105CJW	magnesium transporter
CS374_03505	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CS374_03510	ENOG4105CPK	Glycosyl transferase (Group 1
CS374_03520	ENOG4107SF0	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CS374_03535	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CS374_03545	ENOG4105K70	DNA-binding protein
CS374_03595	ENOG4108IJ1	Dehydrogenase
CS374_03600	ENOG4105ESV	Glycosyl transferase, family 4
CS374_03610	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CS374_03660	ENOG4107VPC	Peptidyl-arginine deiminase
CS374_03675	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CS374_03680	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CS374_03685	ENOG4105DUX	Transporter
CS374_03710	ENOG4105C31	Tryptophanyl-tRNA synthetase
CS374_03720	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CS374_03725	ENOG4105E0X	reductase
CS374_03740	ENOG4105KRF	dihydroneopterin aldolase
CS374_03765	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CS374_03770	ENOG4105C1J	atp-dependent rna helicase
CS374_03820	ENOG4105D41	biosynthesis protein thiH
CS374_03825	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CS374_03830	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CS374_03835	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CS374_03870	ENOG4105K5M	30s ribosomal protein S16
CS374_03880	ENOG4107R5Z	Oxidoreductase domain protein
CS374_03885	ENOG4105Q2H	domain protein
CS374_03890	ENOG4105HDK	L-asparaginase
CS374_03910	ENOG4105DFA	alanine racemase domain protein
CS374_03950	ENOG4106Z4W	(LipO)protein
CS374_03955	ENOG4108HAB	
CS374_03960	ENOG4106DYJ	
CS374_03965	ENOG4106UA3	
CS374_03980	ENOG4105WXV	50S ribosomal protein L32
CS374_03985	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CS374_03990	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CS374_03995	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CS374_04005	ENOG4108ZJ4	polysaccharide deacetylase
CS374_04010	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CS374_04015	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
CS374_04020	ENOG4105C2W	permease
CS374_04060	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CS374_04075	ENOG4105C1Q	protoporphyrinogen oxidase
CS374_04090	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CS374_04095	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CS374_04105	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
CS374_04170	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CS374_04175	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CS374_04180	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CS374_04190	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CS374_04210	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
CS374_04215	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CS374_04220	ENOG4105CFH	Aspartokinase
CS374_04225	ENOG4105CAK	Cell division ATP-binding protein ftsE
CS374_04230	ENOG4105DR5	peptidase
CS374_04235	ENOG4105C3G	gtp-binding protein
CS374_04240	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CS374_04245	ENOG4105KNE	Phosphatidate cytidylyltransferase
CS374_04250	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CS374_04260	ENOG4105E2D	ec 3.2.1.52
CS374_04265	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CS374_04275	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CS374_04280	ENOG4105C0B	DNA polymerase III (alpha subunit)
CS374_04315	ENOG4105KG3	cytidine deaminase
CS374_04325	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CS374_04330	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CS374_04345	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
CS374_04350	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
CS374_04355	ENOG4105CHH	sulfate transporter
CS374_04375	ENOG4108HGU	Histidine kinase
CS374_04390	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CS374_04395	ENOG4105D17	glycoside hydrolase, family 3 domain protein
CS374_04420	ENOG4107RN3	metallophosphoesterase
CS374_04425	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CS374_04435	ENOG4105J5G	Transferase hexapeptide repeat containing protein
CS374_04440	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CS374_04480	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CS374_04495	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CS374_04500	ENOG4105C1A	potassium transporter peripheral membrane
CS374_04505	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CS374_04570	ENOG4105C5H	ABC transporter
CS374_04575	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CS374_04580	ENOG4107S52	alpha-2-macroglobulin domain protein
CS374_04585	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CS374_04590	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CS374_04600	ENOG4105C5H	ABC transporter
CS374_04605	ENOG4108MCP	Propeptide_C25
CS374_04625	ENOG4105BZU	Histidine kinase
CS374_04630	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CS374_04645	ENOG4107RH7	Nicotinate phosphoribosyltransferase
CS374_04650	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CS374_04665	ENOG4105F32	YngK protein
CS374_04670	ENOG4107QUV	Domain protein
CS374_04695	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CS374_04700	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CS374_04705	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CS374_04710	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CS374_04715	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
CS374_04720	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CS374_04725	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CS374_04730	ENOG4107X35	defense response to bacterium
CS374_04765	ENOG4105EJQ	L-serine dehydratase
CS374_04780	ENOG4105C2X	Arabinose 5-phosphate isomerase
CS374_04795	ENOG4108RMU	ferritin dps family protein
CS374_04820	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CS374_04825	ENOG4105CDY	transcriptional regulatory protein
CS374_04830	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CS374_04880	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
CS374_04895	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
CS374_04905	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CS374_04915	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CS374_04930	ENOG4105CUT	histidyl-tRNA synthetase
CS374_04935	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
CS374_04940	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CS374_04980	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
CS374_04990	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CS374_04995	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CS374_05015	ENOG4107QUV	Domain protein
CS374_05020	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CS374_05030	ENOG4105EGD	dinuclear metal center protein, YbgI family
CS374_05040	ENOG4107ZT5	Thiol disulfide interchange protein
CS374_05065	ENOG4105EYW	Ion transport protein
CS374_05070	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CS374_05075	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
CS374_05080	ENOG4105BZ8	glutamate synthase
CS374_05105	ENOG4108Z66	YbaK ebsC protein
CS374_05115	ENOG4105CVJ	phosphoglycerate mutase
CS374_05140	ENOG4106QXG	Arginine-specific protease ArgI polyprotein
CS374_05150	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CS374_05160	ENOG4105CBG	Sulfatase
CS374_05185	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
CS374_05190	ENOG4105D05	Receptor
CS374_05200	ENOG4105HMI	Membrane
CS374_05210	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CS374_05215	ENOG4105C3F	Signal peptidase i
CS374_05230	ENOG4105EAH	synthase
CS374_05235	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CS374_05245	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CS374_05250	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CS374_05255	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CS374_05305	ENOG4105D64	Mechanosensitive ion channel
CS374_05320	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CS374_05340	ENOG4105KDC	50s ribosomal protein l28
CS374_05345	ENOG41083ND	50S ribosomal protein L33
CS374_05355	ENOG4105CYC	Transferase
CS374_05375	ENOG4105CX6	glutaminyL-tRNA synthetase
CS374_05380	ENOG4105C02	permease
CS374_05395	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CS374_05435	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CS374_05440	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CS374_05445	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CS374_05450	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CS374_05455	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CS374_05460	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CS374_05465	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CS374_05470	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CS374_05475	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CS374_05480	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CS374_05485	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CS374_05490	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CS374_05495	ENOG41062E3	50S ribosomal protein L29
CS374_05500	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CS374_05505	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CS374_05510	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CS374_05515	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CS374_05520	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CS374_05525	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CS374_05530	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CS374_05535	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CS374_05540	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CS374_05545	ENOG41084HK	50S ribosomal protein L30
CS374_05550	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CS374_05555	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CS374_05565	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CS374_05570	ENOG410864M	50S ribosomal protein L36
CS374_05575	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CS374_05580	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CS374_05585	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CS374_05590	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CS374_05595	ENOG4108ZT0	50S ribosomal protein l17
CS374_05610	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CS374_05615	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CS374_05620	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CS374_05640	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CS374_05700	ENOG4106PHI	plasmid recombination enzyme
CS374_05790	ENOG4105DGW	oligopeptidase A
CS374_05810	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CS374_05815	ENOG4105C2M	dna polymerase I
CS374_05855	ENOG4107RQX	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
CS374_05875	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CS374_05905	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CS374_05910	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CS374_05915	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CS374_05920	ENOG4105CRE	cytochrome C
CS374_05930	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
CS374_05935	ENOG4108W6G	cytochrome C
CS374_05950	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CS374_05970	ENOG4108IQE	Amp-dependent synthetase and ligase
CS374_05980	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CS374_05995	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CS374_06005	ENOG4105EAA	nucleoside
CS374_06040	ENOG4105KME	endoribonuclease L-psp
CS374_06045	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CS374_06050	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CS374_06065	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CS374_06070	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CS374_06075	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CS374_06080	ENOG4105CN1	protease
CS374_06095	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
CS374_06100	ENOG4105BZW	Glycerate kinase
CS374_06125	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
CS374_06135	ENOG4105CGP	Urocanate hydratase
CS374_06140	ENOG41080R2	UPF0102 protein
CS374_06155	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CS374_06160	ENOG4105C8N	cysteinyl-tRNA synthetase
CS374_06170	ENOG4105K64	Glycosyl transferase, family 2
CS374_06190	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CS374_06195	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
CS374_06230	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CS374_06285	ENOG4105DBI	uridine monophosphokinase
CS374_06290	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CS374_06295	ENOG4108UVJ	appr-1-p processing domain protein
CS374_06305	ENOG4105VG1	fes assembly suf system protein
CS374_06310	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CS374_06315	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CS374_06320	ENOG4108JA2	transcriptioN-repair coupling factor
CS374_06325	ENOG4106CKV	Pap2 superfamily protein
CS374_06330	ENOG4105CSM	endonuclease III
CS374_06335	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CS374_06350	ENOG4105C0P	Mg chelatase subunit ChlI
CS374_06360	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CS374_06365	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CS374_06370	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CS374_06375	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CS374_06380	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CS374_06390	ENOG4105DIK	(ABC) transporter
CS374_06405	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CS374_06420	ENOG4105WYW	fructose-bisphosphate aldolase
CS374_06425	ENOG4105C5Z	peptidase
CS374_06430	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
CS374_06450	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CS374_06455	ENOG4108YZG	isomerase
CS374_06465	ENOG4105C6K	Malic enzyme
CS374_06475	ENOG4107RBB	ABC transporter, permease
CS374_06480	ENOG4105C19	ABC transporter
CS374_06485	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CS374_06505	ENOG4105E6M	Sulphatase-modifying factor protein
CS374_06525	ENOG4105CAH	Chromate
CS374_06585	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
CS374_06590	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
CS374_06595	ENOG4105D6A	Electron transport complex
CS374_06600	ENOG4108UQQ	Electron transport complex
CS374_06605	ENOG4105DZB	Electron transport complex
CS374_06610	ENOG4105DGN	Electron transport complex
CS374_06615	ENOG4105CJ2	(LipO)protein
CS374_06625	ENOG4105CKK	Glycosyl transferase, family 2
CS374_06640	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CS374_06645	ENOG4105K46	50S ribosomal protein l27
CS374_06650	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CS374_06670	ENOG4105DJT	lAO AO transport system ATPase
CS374_06685	ENOG4105C84	Histidine ammonia-lyase
CS374_06690	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
CS374_06705	ENOG4105CI2	imidazolone-5-propionate hydrolase
CS374_06710	ENOG4105CCS	Glutamate formiminotransferase
CS374_06725	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CS374_06735	ENOG4105CKK	Glycosyl transferase, family 2
CS374_06740	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CS374_06765	ENOG4105C28	cystathionine
CS374_06780	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CS374_06785	ENOG4105CMR	udp-glucose 4-epimerase
CS374_06835	ENOG4105CXT	aspartate transcarbamylase
CS374_06840	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
CS374_06845	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
CS374_06850	ENOG4108V0P	LemA family
CS374_06870	ENOG4105DR4	Methyltransferase
CS374_06885	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
CS374_06890	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CS374_06920	ENOG4108UJD	30S ribosomal protein S9
CS374_06925	ENOG4105CE9	30S ribosomal protein S2
CS374_06930	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CS374_06935	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CS374_06940	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
CS374_06950	ENOG4105DZP	Membrane-associated zinc metalloprotease
CS374_06955	ENOG4105C98	muts2 protein
CS374_06960	ENOG41083X6	30S ribosomal protein S21
CS374_06980	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CS374_07000	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CS374_07005	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CS374_07010	ENOG4107VNI	ribosomal protein l10
CS374_07015	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CS374_07020	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CS374_07025	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CS374_07030	ENOG4105IJJ	transcriptional regulator, crp fnr family
CS374_07040	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CS374_07050	ENOG4105MA4	psp1 domain protein
CS374_07055	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
CS374_07085	ENOG41061HS	cysteine-type endopeptidase activity
CS374_07090	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CS374_07105	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CS374_07110	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CS374_07115	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CS374_07120	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CS374_07185	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
CS374_07190	ENOG4105DQU	oxidoreductase, subunit beta
CS374_07195	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CS374_07200	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CS374_07210	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
CS374_07255	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CS374_07260	ENOG4105D06	uba thif-type nad fad binding protein
CS374_07265	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CS374_07285	ENOG4105C37	(CBS) domain
CS374_07310	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CS374_07315	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CS374_07320	ENOG4107XWZ	ferric uptake regulator
CS374_07330	ENOG4105DG6	mannose-6-phosphate isomerase
CS374_07345	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CS374_07360	ENOG4105CSA	Coproporphyrinogen iii oxidase
CS374_07370	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CS374_07385	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CS374_07395	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CS374_07405	ENOG4105VIE	preprotein translocase, subunit YajC
CS374_07410	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CS374_07415	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CS374_07430	ENOG4105CZH	peptidase
CS374_07455	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CS374_07460	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CS374_07470	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CS374_07480	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CS374_07485	ENOG4105C5Z	peptidase
CS374_07490	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CS374_07495	ENOG4108MCP	Propeptide_C25
CS374_07520	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CS374_07525	ENOG4108JIC	nucleoside recognition domain protein
CS374_07530	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CS374_07540	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CS374_07555	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CS374_07570	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CS374_07575	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CS374_07580	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CS374_07585	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CS374_07595	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CS374_07600	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CS374_07605	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CS374_07610	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CS374_07615	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CS374_07620	ENOG4107QMG	Nad synthetase
CS374_07625	ENOG4107RBI	VanW family
CS374_07670	ENOG4105CIN	aminoacyl-histidine dipeptidase
CS374_07675	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CS374_07770	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
CS374_07775	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CS374_07780	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CS374_07785	ENOG4105D0C	transport protein
CS374_07815	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CS374_07825	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CS374_07830	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CS374_07840	ENOG4105CJN	penicillin-binding protein
CS374_07845	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CS374_07850	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CS374_07855	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CS374_07865	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CS374_07870	ENOG4105DFU	Cell wall formation (By similarity)
CS374_07880	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CS374_07885	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CS374_07905	ENOG4105EN6	Membrane
CS374_07910	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CS374_07915	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CS374_07920	ENOG41081WG	50s ribosomal protein l31
CS374_07925	ENOG4105C0H	protease
CS374_07930	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CS374_07935	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
CS374_07940	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CS374_07945	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CS374_07955	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CS374_07970	ENOG4105CAT	Cytidine monophosphate kinase
CS374_07975	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CS374_08030	ENOG4108JU3	Alkyl hydroperoxide reductase
CS374_08035	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CS374_08050	ENOG4105CP7	Triose-phosphate isomerase
CS374_08060	ENOG4105EUJ	GTP cyclohydrolase i
CS374_08075	ENOG4105VFU	Rna-binding protein
CS374_08080	ENOG4108IUZ	ABC transporter
CS374_08085	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CS374_08090	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CS374_08110	ENOG4107S0N	DJ-1 family
CS374_08115	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CS374_08120	ENOG4105C3S	Mate efflux family protein
CS374_08125	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CS374_08130	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CS374_08145	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CS374_08155	ENOG4105E0A	ABC, transporter
CS374_08160	ENOG4105EHG	Permease protein
CS374_08195	ENOG4105EAC	phosphoserine phosphatase
CS374_08205	ENOG4105VG0	50S ribosomal protein l34
CS374_08210	ENOG4108Z03	MAF-like protein
CS374_08215	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
CS374_08235	ENOG4105EPC	oxidoreductase
CS374_08240	ENOG4105CNT	hydrolase family 2
CS374_08250	ENOG4105D05	Receptor
CS374_08255	ENOG4107PPM	cobalt chelatase
CS374_08265	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
CS374_08270	ENOG4105E0A	ABC, transporter
CS374_08290	ENOG4105EMU	Dehydrogenase
CS374_08330	ENOG4105C19	ABC transporter
CS374_08340	ENOG4107SG5	Dehydrogenase
CS374_08345	ENOG4107S8T	NAD-dependent 4-hydroxybutyrate dehydrogenase
CS374_08350	ENOG4105CYC	Transferase
CS374_08365	ENOG4105RWF	major outer membrane protein OmpA
CS374_08370	ENOG4105RWF	major outer membrane protein OmpA
CS374_08390	ENOG4108YZT	Adenosylcobinamide kinase
CS374_08395	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CS374_08400	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
CS374_08410	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CS374_08420	ENOG4105D05	Receptor
CS374_08430	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CS374_08435	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CS374_08445	ENOG4105DDQ	anthranilate synthase
CS374_08470	ENOG4106N3A	copper homeostasis protein cutc
CS374_08495	ENOG4105GR3	Histidine kinase
CS374_08515	ENOG4105K4H	Nlp p60 protein
CS374_08520	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
CS374_08545	ENOG4105CPF	Cell wall formation (By similarity)
CS374_08550	ENOG4105C34	Pseudouridine synthase
CS374_08565	ENOG4108R6K	riboflavin synthase, subunit alpha
CS374_08575	ENOG4105C9B	Cysteine desulfurase
CS374_08580	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CS374_08590	ENOG4108Z6B	deaminase
CS374_08595	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CS374_08605	ENOG4108RWN	rrna methyltransferase
CS374_08615	ENOG4105BZU	Histidine kinase
CS374_08620	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CS374_08630	ENOG4105ECJ	Glycosyl Transferase
CS374_08640	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CS374_08645	ENOG4105CFP	Peptidase U32
CS374_08660	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CS374_08675	ENOG4105DGW	oligopeptidase A
CS374_08695	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CS374_08700	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CS374_08705	ENOG4107S1W	4-alpha-glucanotransferase
CS374_08730	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CS374_08745	ENOG4105C1G	acyl-Coa dehydrogenase
CS374_08750	ENOG4105C10	Electron transfer flavoprotein
CS374_08755	ENOG4105BZJ	Electron transfer flavoprotein
CS374_08760	ENOG41072GX	Peptidase M22 Glycoprotease
CS374_08790	ENOG4105F8V	Hydrolase, tatD family
CS374_08820	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CS374_08825	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CS374_08830	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CS374_08835	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
CS374_08840	ENOG4108JQC	penicillin-binding protein 1A
CS374_08845	ENOG4105HFZ	Membrane
CS374_08850	ENOG4105C8T	Leucyl-tRNA synthetase
CS374_08865	ENOG4105DZ0	fad dependent oxidoreductase
CS374_08870	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CS374_08880	ENOG4107QN2	dihydrolipoyl dehydrogenase
CS374_08885	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
CS374_08890	ENOG4105CNW	domain protein
CS374_08895	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CS374_08900	ENOG4105DGA	Diaminopimelate dehydrogenase
CS374_08905	ENOG4107R6T	Involved in the transcription termination process (By similarity)
CS374_08925	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CS374_08955	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CS374_08960	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CS374_08990	ENOG4105C2F	Histidine kinase
CS374_08995	ENOG4105DY9	regulatoR
CS374_09065	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CS374_09075	ENOG4105BZU	Histidine kinase
CS374_09080	ENOG4105WH1	Two component transcriptional regulator luxr family
CS374_09090	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CS374_09095	ENOG4105IUR	peptidase C10
CS374_09110	ENOG4107VPC	Peptidyl-arginine deiminase
CS374_09120	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
CS374_09130	ENOG4105C6E	dna polymerase iii
CS374_09135	ENOG4107GFK	fumarate
CS374_09145	ENOG4105EA8	2-Nitropropane dioxygenase
CS374_09160	ENOG4105D0C	transport protein
CS374_09205	ENOG4105C0F	tryptophanase EC 4.1.99.1
CS374_09235	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CS374_09255	ENOG4105CJN	penicillin-binding protein
CS374_09260	ENOG4105CNI	cell division protein FtsW
CS374_09285	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CS374_09315	ENOG4105D7T	ABC transporter
CS374_09330	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
CS374_09370	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CS374_09375	ENOG4105CRK	lysyL-tRNA synthetase
CS374_09385	ENOG4107QP8	phosphohexose isomerase
CS374_09395	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CS374_09400	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CS374_09405	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CS374_09420	ENOG4105C5Z	peptidase
CS374_09425	ENOG4105C12	Phosphoribosylglycinamide synthetase
CS374_09435	ENOG4105VDT	-acetyltransferase
CS374_09455	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
CS374_09460	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CS374_09475	ENOG4107TE5	Lipid kinase
CS374_09480	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CS374_09485	ENOG4105CPK	Glycosyl transferase (Group 1
CS374_09500	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CS374_09505	ENOG4107R0I	Cell wall formation (By similarity)
CS374_09520	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CS374_09525	ENOG4105KT5	UmuD protein
CS374_09550	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CS374_09555	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CS374_09560	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CS374_09565	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CS374_09575	ENOG4105CD5	CoA-binding domain protein
CS374_09585	ENOG4106QXG	Arginine-specific protease ArgI polyprotein
CS374_09585	ENOG4106QXG	Arginine-specific protease ArgI polyprotein
CS374_09595	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CS374_09600	ENOG4108IAB	Phoh family
CS374_09605	ENOG4105CKU	formyltetrahydrofolate synthetase
CS374_09640	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CS374_09645	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CS374_09675	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CS374_09685	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CS374_09690	ENOG4105C5X	domain protein
CS374_09695	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CS374_09725	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CS374_09740	ENOG4105CE1	Ferrous iron transport protein b
CS374_09755	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CS374_09760	ENOG4105C30	Nad-dependent epimerase dehydratase
CS374_09765	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
CS374_09775	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
CS374_09780	ENOG4105CZH	peptidase
CS374_09790	ENOG4105C98	muts2 protein
CS374_09805	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CS374_09810	ENOG4107QQG	Dehydrogenase
CS374_09825	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CS374_09835	ENOG4105C8Y	Acetylornithine aminotransferase
CS374_09845	ENOG4105C26	Dehydrogenase
CS374_09895	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CS374_09900	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CS374_09910	ENOG4105C03	ribonuclease
CS374_09915	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CS374_09925	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CS374_09945	ENOG4105E9Q	Acyl-transferase
CS374_09960	ENOG4105D49	3-dehydroquinate synthase
CS374_09965	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CS374_09975	ENOG4105CDU	Replicative dna helicase
CS374_09980	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CS374_09990	ENOG4108XG4	DNA-binding transcriptional regulator
CS374_09995	ENOG4105CHR	reductase
CS374_10005	ENOG4105WH1	Two component transcriptional regulator luxr family
CS374_10015	ENOG4105EXW	epimerase dehydratase
CS374_10020	ENOG4107R37	Glutamate dehydrogenase
CS374_10040	ENOG4105C5H	ABC transporter
CS374_10045	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CS374_10060	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
CS374_10090	ENOG4108B1Q	Ribonuclease
CS374_10100	ENOG4108Z0R	Transferase
CS374_10120	ENOG4105CFG	Acts as a chaperone (By similarity)
CS374_10130	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CS374_10175	ENOG4105MZU	cell filamentation protein
CS374_10185	ENOG4105VTR	Integrase
CS374_10225	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CS374_10235	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CS374_10245	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CS374_10255	ENOG4108JJA	ABC, transporter
CS374_10480	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CS374_10490	ENOG4105C5I	Dehydrogenase
CS374_10515	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
CS374_10545	ENOG4105BZ1	(ABC) transporter
CS374_10570	ENOG4105CN1	protease
CS374_10575	ENOG410600T	transposase
CS374_10590	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CS374_10600	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
CS374_10605	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
CS374_10610	ENOG4105FRY	Dehydrogenase
CS374_10630	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
CS374_10635	ENOG4107CHF	5,6-aminomutase beta subunit
CS374_10645	ENOG4105C1G	acyl-Coa dehydrogenase
CS374_10650	ENOG4105BZJ	Electron transfer flavoprotein
CS374_10655	ENOG4105C10	Electron transfer flavoprotein
CS374_10660	ENOG4105E39	Enoyl-CoA hydratase
CS374_10665	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CS374_10670	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CS374_10675	ENOG4108IJ2	phosphate acetyltransferase
CS374_10685	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CS374_10695	ENOG4105N5T	Radical SAM Protein
CS374_10730	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CS374_10745	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CS374_10765	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CS374_10775	ENOG4107RJ1	sodium solute
CS374_10785	ENOG4105D1H	recombination factor protein RarA
CS374_10790	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
CS374_10795	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CS374_10800	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
CS374_10805	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CS374_10815	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CS374_10820	ENOG4107QI1	Mate efflux family protein
CS374_10830	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CS374_10840	ENOG4105C5S	asparaginyl-tRNA synthetase
CS374_10845	ENOG4105FE9	pseudouridine synthase
CS374_10850	ENOG4107QTF	adenylosuccinate lyase
CS374_10855	ENOG4108WBT	adenosyltransferase
CS374_10865	ENOG4105C2W	permease
CS374_10870	ENOG4108VVK	transcriptional Regulator, AsnC
CS374_10875	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)