locus-tag	class	description
P9301_00001	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
P9301_00021	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
P9301_00031	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
P9301_00081	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
P9301_00101	ENOG4107SGM	protein serine threonine phosphatase
P9301_00111	ENOG4105CH7	arginosuccinase
P9301_00121	ENOG4105VFU	Rna-binding protein
P9301_00141	ENOG4105E0X	reductase
P9301_00151	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
P9301_00161	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
P9301_00181	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
P9301_00191	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
P9301_00201	ENOG4105D4A	Cell wall formation (By similarity)
P9301_00211	ENOG4105DFU	Cell wall formation (By similarity)
P9301_00231	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
P9301_00251	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
P9301_00261	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
P9301_00271	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
P9301_00351	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
P9301_00361	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
P9301_00391	ENOG4107RDJ	Sulfotransferase
P9301_00431	ENOG4105CJN	penicillin-binding protein
P9301_00451	ENOG4105CNW	domain protein
P9301_00461	ENOG4105CNW	domain protein
P9301_00471	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
P9301_00481	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
P9301_00491	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
P9301_00511	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
P9301_00521	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
P9301_00531	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
P9301_00711	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
P9301_00791	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
P9301_00881	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
P9301_00891	ENOG4105D1H	recombination factor protein RarA
P9301_00911	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
P9301_00921	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
P9301_00931	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
P9301_00941	ENOG4105CEP	NADH dehydrogenase
P9301_00961	ENOG4105CZN	Potassium uptake protein
P9301_01021	ENOG4105C5H	ABC transporter
P9301_01041	ENOG4105C0H	protease
P9301_01161	ENOG4105CVB	Vitamin K epoxide reductase
P9301_01171	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
P9301_01191	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
P9301_01291	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
P9301_01301	ENOG4108DIF	synthase (EC 4.2.1.75)
P9301_01321	ENOG4105CVN	desaturase
P9301_01381	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
P9301_01391	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
P9301_01411	ENOG4105VUV	UPF0367 protein
P9301_01421	ENOG4108JJB	ABC transporter
P9301_01471	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
P9301_01481	ENOG4107QMP	dna polymerase iii subunits gamma and tau
P9301_01491	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
P9301_01501	ENOG4105C59	p-type ATPase
P9301_01511	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
P9301_01521	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
P9301_01541	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
P9301_01551	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
P9301_01601	ENOG4105DJ0	Poly(A) Polymerase
P9301_01621	ENOG4105FE1	phytoene synthase
P9301_01631	ENOG4105CVN	desaturase
P9301_01641	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
P9301_01681	ENOG4105D65	subunit l
P9301_01691	ENOG4105C8S	subunit m
P9301_01761	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
P9301_01771	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
P9301_01781	ENOG4107YX3	NADH dehydrogenase subunit j
P9301_01791	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
P9301_01801	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
P9301_01841	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
P9301_01861	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
P9301_01871	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
P9301_01891	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
P9301_01901	ENOG4105C3J	Cysteine desulfurase
P9301_01911	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
P9301_01921	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
P9301_01931	ENOG4105WGP	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity)
P9301_01971	ENOG4105E4F	Isochorismate synthase
P9301_01981	ENOG4105D7Z	glutathione synthase
P9301_02001	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
P9301_02021	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
P9301_02041	ENOG4105DDQ	anthranilate synthase
P9301_02051	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
P9301_02071	ENOG4105C75	arginyL-tRNA synthetase
P9301_02081	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
P9301_02091	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
P9301_02121	ENOG4108JQ6	ABC transporter
P9301_02141	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
P9301_02151	ENOG4105BZA	Phosphoglycerate kinase
P9301_02171	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
P9301_02181	ENOG4105CIH	Imidazole acetol-phosphate transaminase
P9301_02191	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
P9301_02201	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
P9301_02211	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
P9301_02221	ENOG4107Z3D	50S ribosomal protein l10
P9301_02231	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
P9301_02241	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
P9301_02271	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
P9301_02281	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
P9301_02311	ENOG4105C3M	thioredoxin reductase
P9301_02351	ENOG4105CHH	sulfate transporter
P9301_02361	ENOG4105D52	delta-aminolevulinic acid dehydratase
P9301_02391	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
P9301_02421	ENOG4105CHF	Glutathione S-transferase
P9301_02431	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
P9301_02451	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
P9301_02461	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
P9301_02491	ENOG4107RIQ	Sulfate adenylate transferase
P9301_02501	ENOG4105CPJ	photosystem II manganese-stabilizing
P9301_02551	ENOG4105CXT	aspartate transcarbamylase
P9301_02561	ENOG4108VX5	3-methyladenine DNA glycosylase
P9301_02571	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
P9301_02601	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
P9301_02631	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
P9301_02641	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
P9301_02651	ENOG4108S64	thioredoxin-like protein txlA
P9301_02671	ENOG4105DHP	deoxycytidine triphosphate deaminase
P9301_02701	ENOG4108R0D	protein with myosin-like
P9301_02731	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
P9301_02741	ENOG4105WIA	photosystem II reaction center protein H
P9301_02771	ENOG4106A1F	This protein is a component of the reaction center of photosystem II (By similarity)
P9301_02781	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
P9301_02791	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
P9301_02801	ENOG4105CEV	competence damage-inducible protein
P9301_02811	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
P9301_02851	ENOG4105PW4	Sugar fermentation stimulation protein homolog
P9301_02871	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
P9301_02891	ENOG4105DC1	bifunctional purine biosynthesis protein purh
P9301_02921	ENOG4108YBA	Histidine kinase
P9301_02931	ENOG4107Z12	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
P9301_02941	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
P9301_02981	ENOG4105C37	(CBS) domain
P9301_02991	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
P9301_03021	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
P9301_03031	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
P9301_03051	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
P9301_03061	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
P9301_03091	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
P9301_03111	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
P9301_03121	ENOG4105EET	magnesium chelatase
P9301_03151	ENOG4105CHW	UPF0052 protein
P9301_03161	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
P9301_03171	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
P9301_03181	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
P9301_03201	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
P9301_03211	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
P9301_03231	ENOG4106AY4	Required for PSII activity (By similarity)
P9301_03241	ENOG4105YEU	This protein is a component of the reaction center of photosystem II (By similarity)
P9301_03251	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
P9301_03261	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
P9301_03271	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
P9301_03281	ENOG4105C4R	Atp-dependent dna helicase
P9301_03301	ENOG4108RIN	C-phycoerythrin class I beta chain
P9301_03311	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
P9301_03351	ENOG4107S5T	Carbohydrate kinase
P9301_03361	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
P9301_03371	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
P9301_03381	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
P9301_03401	ENOG4105YVZ	photosystem II
P9301_03431	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
P9301_03461	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
P9301_03481	ENOG4107XW6	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
P9301_03491	ENOG4105DCI	Phosphohydrolase
P9301_03511	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
P9301_03521	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
P9301_03551	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
P9301_03561	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
P9301_03581	ENOG4105C26	Dehydrogenase
P9301_03761	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
P9301_03801	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
P9301_03921	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
P9301_03941	ENOG4105DWF	phosphomethylpyrimidine kinase
P9301_04071	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
P9301_04091	ENOG4105DVK	Precorrin-2 c20-methyltransferase
P9301_04111	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
P9301_04121	ENOG4107U45	Cobalt transport protein
P9301_04151	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
P9301_04201	ENOG4105MS2	ribosomal subunit Interface protein
P9301_04211	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
P9301_04221	ENOG4108IQE	Amp-dependent synthetase and ligase
P9301_04251	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
P9301_04261	ENOG4105C6T	cysteine synthase
P9301_04271	ENOG4105C28	cystathionine
P9301_04281	ENOG4105C28	cystathionine
P9301_04291	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
P9301_04301	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
P9301_04321	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
P9301_04381	ENOG41083MR	nifu domain-containing protein
P9301_04391	ENOG4105DWT	malate dehydrogenase (quinone)
P9301_04401	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
P9301_04421	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
P9301_04471	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
P9301_04511	ENOG4105BZ4	penicillin-binding protein
P9301_04521	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
P9301_04541	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
P9301_04551	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
P9301_04581	ENOG4105C19	ABC transporter
P9301_04591	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
P9301_04601	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
P9301_04631	ENOG4108K7V	UPF0284 protein
P9301_04661	ENOG4108R6K	riboflavin synthase, subunit alpha
P9301_04721	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
P9301_04761	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
P9301_04781	ENOG4105CHR	reductase
P9301_04791	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
P9301_04821	ENOG4105C9X	ppx gppa phosphatase
P9301_04841	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
P9301_04851	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
P9301_04861	ENOG4105D1D	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
P9301_04871	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
P9301_04921	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
P9301_04941	ENOG4108VV8	photosystem i
P9301_04951	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
P9301_04981	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
P9301_05001	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
P9301_05061	ENOG4108VPT	UPF0234 protein
P9301_05101	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
P9301_05141	ENOG4105C8M	UPF0272 protein
P9301_05161	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
P9301_05171	ENOG4105CKI	cobalamin synthesis protein
P9301_05181	ENOG4105KZX	Pterin carbinolamine dehydratase
P9301_05201	ENOG4105CTD	carboxy-peptidase
P9301_05211	ENOG4105F0N	pyrophosphate phospho-hydrolase
P9301_05221	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
P9301_05231	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
P9301_05261	ENOG4105CAS	nag kinase
P9301_05301	ENOG4105QUC	reductase
P9301_05331	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
P9301_05351	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
P9301_05381	ENOG4105F0N	pyrophosphate phospho-hydrolase
P9301_05391	ENOG41080E8	Transcriptional regulator, Spx MgsR family
P9301_05411	ENOG4105CVJ	phosphoglycerate mutase
P9301_05441	ENOG4105CJN	penicillin-binding protein
P9301_05451	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
P9301_05461	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
P9301_05471	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
P9301_05481	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
P9301_05511	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
P9301_05521	ENOG4105C7K	acetolactate synthase
P9301_05561	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
P9301_05581	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
P9301_05591	ENOG4105E6N	shikimate quinate 5-dehydrogenase
P9301_05601	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
P9301_05621	ENOG4105EUJ	GTP cyclohydrolase i
P9301_05631	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
P9301_05651	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
P9301_05691	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
P9301_05701	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
P9301_05711	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
P9301_05741	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
P9301_05751	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
P9301_05761	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
P9301_05771	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
P9301_05841	ENOG4105KME	endoribonuclease L-psp
P9301_05851	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
P9301_05861	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
P9301_05871	ENOG4105BZ1	(ABC) transporter
P9301_05881	ENOG4107WJM	-acetyltransferase
P9301_05911	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
P9301_05931	ENOG4105DC8	reductase
P9301_05951	ENOG4105EKE	dihydroorotase
P9301_05961	ENOG41069EW	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
P9301_05981	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
P9301_06031	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
P9301_06041	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
P9301_06061	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
P9301_06071	ENOG4105H0N	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I
P9301_06091	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
P9301_06101	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
P9301_06161	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
P9301_06171	ENOG4107ZVW	dihydroneopterin aldolase
P9301_06191	ENOG4105DGW	oligopeptidase A
P9301_06201	ENOG4105C8S	subunit m
P9301_06211	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
P9301_06221	ENOG4105CHC	glucokinase (EC 2.7.1.2)
P9301_06231	ENOG4105C22	threonyL-tRNA synthetase
P9301_06241	ENOG4105C31	Tryptophanyl-tRNA synthetase
P9301_06331	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
P9301_06341	ENOG4108IPT	Naphthoate synthase
P9301_06351	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
P9301_06371	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
P9301_06381	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
P9301_06391	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
P9301_06401	ENOG4108N5B	2-phosphosulfolactate phosphatase
P9301_06421	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
P9301_06471	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
P9301_06491	ENOG4105CUT	histidyl-tRNA synthetase
P9301_06541	ENOG41065W4	chlorophyll a b binding light harvesting protein
P9301_06601	ENOG4108JT6	LycopEne
P9301_06631	ENOG4108RWI	nicotinamidase
P9301_06701	ENOG4105CVG	Homoserine O-transsuccinylase
P9301_06711	ENOG4105CHH	sulfate transporter
P9301_06731	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
P9301_06891	ENOG4105D7Q	type ii secretion system
P9301_06901	ENOG4105CZX	twitching motility protein
P9301_06911	ENOG4107QHF	type ii secretion system protein e
P9301_06981	ENOG4108ZUW	Major pilin subunit
P9301_07011	ENOG4106855	Competence protein
P9301_07151	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
P9301_07161	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
P9301_07181	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
P9301_07191	ENOG4108JJB	ABC transporter
P9301_07261	ENOG4107T9Q	phosphonate abc transporter
P9301_07281	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
P9301_07291	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
P9301_07351	ENOG4105D49	3-dehydroquinate synthase
P9301_07361	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
P9301_07411	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
P9301_07741	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
P9301_07751	ENOG4105C8U	phosphate abc transporter
P9301_07761	ENOG4105E2Z	phosphate ABC transporter (Permease
P9301_07771	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
P9301_07821	ENOG4107QRT	dEAD DEAH box helicase
P9301_07831	ENOG4107T0X	DNA ligase
P9301_08011	ENOG4108R9R	May be involved in photosynthetic membrane biogenesis (By similarity)
P9301_08021	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
P9301_08071	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
P9301_08121	ENOG4107R51	Glycosyl transferase, family 2
P9301_08131	ENOG4105CE9	30S ribosomal protein S2
P9301_08141	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
P9301_08181	ENOG4107QHM	Sulfite reductase
P9301_08191	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
P9301_08241	ENOG4108IUZ	ABC transporter
P9301_08251	ENOG4105CRE	cytochrome C
P9301_08261	ENOG4105DJV	ribulose-phosphate 3-epimerase
P9301_08271	ENOG4105CBT	Fructose-1,6-bisphosphatase
P9301_08281	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
P9301_08291	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
P9301_08301	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
P9301_08311	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
P9301_08341	ENOG4105C01	Dihydroxy-acid dehydratase
P9301_08361	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
P9301_08411	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
P9301_08451	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
P9301_08461	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
P9301_08471	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
P9301_08481	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
P9301_08491	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
P9301_08521	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
P9301_08571	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
P9301_08631	ENOG4105CSM	endonuclease III
P9301_08641	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
P9301_08671	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
P9301_08681	ENOG4105DKW	ABC transporter
P9301_08821	ENOG4108IV0	ABC, transporter
P9301_08831	ENOG4105C0Z	ABC transporter
P9301_08851	ENOG4105C32	Amino acid ABC transporter (Permease)
P9301_08871	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
P9301_08881	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
P9301_08891	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
P9301_08901	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
P9301_08911	ENOG4108YZ9	Urea amidohydrolase subunit gamma
P9301_08921	ENOG4105KI2	Urea amidohydrolase subunit beta
P9301_08931	ENOG4105CQM	Urea amidohydrolase subunit alpha
P9301_08941	ENOG4105C3Q	Glycosyl transferase, family 2
P9301_08951	ENOG4107QW3	Sucrose phosphorylase
P9301_08961	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
P9301_09021	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
P9301_09031	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
P9301_09041	ENOG4105BZ1	(ABC) transporter
P9301_09061	ENOG4108I0Q	anthranilate phosphoribosyltransferase
P9301_09071	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
P9301_09091	ENOG4108420	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
P9301_09121	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
P9301_09151	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
P9301_09161	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
P9301_09191	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
P9301_09211	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
P9301_09221	ENOG4105KT5	UmuD protein
P9301_09231	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
P9301_09251	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
P9301_09261	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
P9301_09291	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
P9301_09301	ENOG4107TV7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
P9301_09331	ENOG4105MSA	Photosystem II reaction center W protein
P9301_09341	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
P9301_09401	ENOG4105C5R	Aminotransferase
P9301_09411	ENOG4108Z6B	deaminase
P9301_09421	ENOG4105DY8	decarboxylase
P9301_09441	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
P9301_09511	ENOG4105C7B	Threonine dehydratase
P9301_09521	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
P9301_09531	ENOG4105VGQ	Photosystem I subunit X
P9301_09561	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
P9301_09571	ENOG41083EU	50s ribosomal protein l28
P9301_09581	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
P9301_09591	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
P9301_09621	ENOG4108KBA	Acts as a chaperone (By similarity)
P9301_09631	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
P9301_09651	ENOG4108ZCU	PPIases accelerate the folding of proteins
P9301_09671	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
P9301_09681	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
P9301_09691	ENOG4105C89	phosphohexose isomerase
P9301_09701	ENOG4105C8T	Leucyl-tRNA synthetase
P9301_09721	ENOG4107QI6	Cysteine desulfurase
P9301_09751	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
P9301_09771	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
P9301_09801	ENOG4105CTK	cobaltochelatase, cobn subunit
P9301_09891	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
P9301_09901	ENOG41084GG	50S ribosomal protein L33
P9301_09911	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
P9301_09981	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
P9301_09991	ENOG410902K	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
P9301_10141	ENOG4108790	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
P9301_10241	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
P9301_10271	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
P9301_10281	ENOG4107TS3	membrane protein, TerC
P9301_10381	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
P9301_10391	ENOG4105CTK	cobaltochelatase, cobn subunit
P9301_10411	ENOG4105CP7	Triose-phosphate isomerase
P9301_10431	ENOG4105BZ1	(ABC) transporter
P9301_10451	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
P9301_10511	ENOG4108IUW	ABC transporter
P9301_10681	ENOG410848W	30S ribosomal protein S21
P9301_10701	ENOG4107S03	uridine kinase
P9301_10751	ENOG4105EC3	peptidase S51, dipeptidase E
P9301_10901	ENOG4105CD8	aminopeptidase N
P9301_11331	ENOG4105DIK	(ABC) transporter
P9301_11341	ENOG4105DSE	periplasmic solute binding protein
P9301_11351	ENOG4105CKI	cobalamin synthesis protein
P9301_11471	ENOG4105N7N	Pentapeptide repeat-containing protein
P9301_11541	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
P9301_11601	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
P9301_11621	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
P9301_11661	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
P9301_11681	ENOG4107QVP	Dehydrogenase
P9301_11701	ENOG4108JT6	LycopEne
P9301_11711	ENOG4107RFW	hydrolase family 57
P9301_11721	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
P9301_11751	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
P9301_11761	ENOG4105CTB	Polyprenyl synthetase
P9301_11781	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
P9301_11811	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
P9301_11841	ENOG4105BZU	Histidine kinase
P9301_11871	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
P9301_11911	ENOG4105CXN	decarboxylase
P9301_11981	ENOG4105C8B	TIGR00159 family
P9301_11991	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
P9301_12001	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
P9301_12011	ENOG4105C72	UPF0176 protein
P9301_12031	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
P9301_12041	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
P9301_12061	ENOG4105BZ1	(ABC) transporter
P9301_12081	ENOG4105C1J	atp-dependent rna helicase
P9301_12091	ENOG4107QYX	exodeoxyribonuclease v alpha
P9301_12101	ENOG4107QKA	exodeoxyribonuclease V beta
P9301_12141	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
P9301_12151	ENOG4105CEY	Amp-dependent synthetase and ligase
P9301_12221	ENOG4105EWK	phytoene
P9301_12231	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
P9301_12301	ENOG4107E2E	PKHD-type hydroxylase
P9301_12351	ENOG41085FC	arsR family transcriptional regulator
P9301_12361	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
P9301_12381	ENOG4105CAH	Chromate
P9301_12391	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
P9301_12431	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
P9301_12501	ENOG4105D5T	phosphonate abc transporter
P9301_12511	ENOG4107T9Q	phosphonate abc transporter
P9301_12581	ENOG4105D6J	arsenicaL-resistance protein
P9301_12681	ENOG4105FE9	pseudouridine synthase
P9301_12701	ENOG4108RAV	Conserved protein
P9301_12961	ENOG4105K3M	)-transporter
P9301_13021	ENOG4105C8J	)-transporter
P9301_13091	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
P9301_13111	ENOG4105H3G	oxidoreductase
P9301_13271	ENOG4105C3G	gtp-binding protein
P9301_13281	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
P9301_13301	ENOG4105C8N	cysteinyl-tRNA synthetase
P9301_13311	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
P9301_13331	ENOG4105NZG	Ferredoxin
P9301_13351	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
P9301_13361	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
P9301_13371	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
P9301_13401	ENOG4105C3M	thioredoxin reductase
P9301_13411	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
P9301_13471	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
P9301_13481	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
P9301_13491	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
P9301_13511	ENOG4108Z03	MAF-like protein
P9301_13521	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
P9301_13621	ENOG4107E2E	PKHD-type hydroxylase
P9301_13651	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
P9301_13721	ENOG41065W4	chlorophyll a b binding light harvesting protein
P9301_13731	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
P9301_13781	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
P9301_13791	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
P9301_13851	ENOG4105UVI	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
P9301_13871	ENOG4107RIX	inner membrane protein translocase component YidC
P9301_13881	ENOG4108790	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
P9301_13891	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
P9301_13901	ENOG4105DZP	Membrane-associated zinc metalloprotease
P9301_13911	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
P9301_13921	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
P9301_13931	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
P9301_13981	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
P9301_14001	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
P9301_14031	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
P9301_14071	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
P9301_14081	ENOG4105D2T	synthase
P9301_14101	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
P9301_14111	ENOG4108IAJ	Nad-dependent epimerase dehydratase
P9301_14231	ENOG4105BZ1	(ABC) transporter
P9301_14241	ENOG4105CMR	udp-glucose 4-epimerase
P9301_14251	ENOG4107RA4	Glycosyl transferase (Group 1
P9301_14271	ENOG4105ESV	Glycosyl transferase, family 4
P9301_14391	ENOG4105CHR	reductase
P9301_14411	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
P9301_14421	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
P9301_14441	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
P9301_14481	ENOG4105DBV	ornithine carbamoyltransferase
P9301_14541	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
P9301_14551	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
P9301_14561	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
P9301_14591	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
P9301_14631	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
P9301_14651	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
P9301_14661	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
P9301_14681	ENOG4105HFZ	Membrane
P9301_14701	ENOG41082B1	30S ribosomal protein S16
P9301_14731	ENOG4108JYK	Dehydrogenase
P9301_14741	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
P9301_14761	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
P9301_14771	ENOG4107U7Q	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
P9301_14781	ENOG4108V1T	peptidylprolyl cis-trans isomerase
P9301_14821	ENOG4105DK0	Indole-3-glycerol phosphate synthase
P9301_14851	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
P9301_14871	ENOG4105C8Y	Acetylornithine aminotransferase
P9301_14881	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
P9301_14911	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
P9301_14921	ENOG4105CPF	Cell wall formation (By similarity)
P9301_14951	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
P9301_14961	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
P9301_14991	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
P9301_15001	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
P9301_15011	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
P9301_15071	ENOG4105K70	DNA-binding protein
P9301_15081	ENOG4108IUM	Glycogen debranching enzyme
P9301_15131	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
P9301_15141	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
P9301_15151	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
P9301_15181	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
P9301_15191	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
P9301_15211	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
P9301_15221	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
P9301_15231	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
P9301_15241	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
P9301_15251	ENOG4107QPR	SAICAR synthetase
P9301_15261	ENOG4105C12	Phosphoribosylglycinamide synthetase
P9301_15281	ENOG4105EHU	Circadian clock protein KaiC
P9301_15291	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
P9301_15301	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
P9301_15311	ENOG4105K46	50S ribosomal protein l27
P9301_15321	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
P9301_15331	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
P9301_15341	ENOG4105JFG	SpoIID LytB domain protein
P9301_15351	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
P9301_15391	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
P9301_15421	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
P9301_15481	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
P9301_15491	ENOG4105PDP	Short chain dehydrogenase
P9301_15511	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
P9301_15531	ENOG4105C2I	pirin domain protein
P9301_15581	ENOG4105CBX	hi0933 family
P9301_16211	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
P9301_16221	ENOG4105CFG	Acts as a chaperone (By similarity)
P9301_16231	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
P9301_16241	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
P9301_16261	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
P9301_16271	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
P9301_16281	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
P9301_16291	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
P9301_16301	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
P9301_16321	ENOG4107RAQ	aminopeptidase
P9301_16331	ENOG4105C37	(CBS) domain
P9301_16341	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
P9301_16401	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
P9301_16411	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
P9301_16421	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
P9301_16431	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
P9301_16441	ENOG4105S30	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
P9301_16451	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
P9301_16461	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
P9301_16491	ENOG4107QIV	Cytochrome c biogenesis protein
P9301_16501	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
P9301_16511	ENOG4107Z8Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
P9301_16541	ENOG4105DX0	Hemolysin A
P9301_16561	ENOG4105C9Q	fumarate hydratase class II
P9301_16571	ENOG4105CQR	helicase
P9301_16611	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
P9301_16621	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
P9301_16641	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
P9301_16651	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
P9301_16671	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
P9301_16721	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
P9301_16741	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
P9301_16751	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
P9301_16761	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
P9301_16781	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
P9301_16791	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
P9301_16801	ENOG4105E66	phosphoriboisomerase A
P9301_16811	ENOG4105C0H	protease
P9301_16821	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
P9301_16831	ENOG4105CHV	Transcription elongation factor NusA
P9301_16851	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
P9301_16901	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
P9301_16911	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
P9301_16931	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
P9301_16951	ENOG4105CQC	Prephenate dehydratase
P9301_16971	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
P9301_16981	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
P9301_16991	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
P9301_17001	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
P9301_17011	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
P9301_17021	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
P9301_17061	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
P9301_17111	ENOG4108W6I	photosystem I reaction center protein subunit XI
P9301_17141	ENOG4105CKK	Glycosyl transferase, family 2
P9301_17151	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
P9301_17161	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
P9301_17171	ENOG4105E4R	Precorrin-3B C17-methyltransferase
P9301_17191	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
P9301_17211	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
P9301_17221	ENOG41082HT	Binds the 23S rRNA (By similarity)
P9301_17231	ENOG4108UJD	30S ribosomal protein S9
P9301_17241	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
P9301_17251	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
P9301_17261	ENOG4108ZT0	50S ribosomal protein l17
P9301_17271	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
P9301_17281	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
P9301_17291	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
P9301_17301	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
P9301_17311	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
P9301_17321	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
P9301_17331	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
P9301_17341	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
P9301_17351	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
P9301_17361	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
P9301_17371	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
P9301_17381	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
P9301_17391	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
P9301_17401	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
P9301_17421	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
P9301_17431	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
P9301_17441	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
P9301_17451	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
P9301_17461	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
P9301_17471	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
P9301_17481	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
P9301_17491	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
P9301_17501	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
P9301_17531	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
P9301_17611	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
P9301_17631	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
P9301_17641	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
P9301_17661	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
P9301_17711	ENOG4105CNI	cell division protein FtsW
P9301_17731	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
P9301_17811	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
P9301_17821	ENOG4105CAT	Cytidine monophosphate kinase
P9301_17841	ENOG4108KKY	Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin (By similarity)
P9301_17851	ENOG4108QAI	Catalyzes the two-electron reduction of biliverdin IX- alpha at the C15 methine bridge (By similarity)
P9301_17881	ENOG4108HMX	isocitrate dehydrogenase (NADP)
P9301_17961	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
P9301_17981	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
P9301_17991	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
P9301_18011	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
P9301_18031	ENOG4105CV1	Transketolase (EC 2.2.1.1)
P9301_18041	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
P9301_18071	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
P9301_18081	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
P9301_18101	ENOG4105CRK	lysyL-tRNA synthetase
P9301_18111	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
P9301_18161	ENOG4107T5V	SNARE associated Golgi
P9301_18171	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
P9301_18181	ENOG4105K8N	protein family UPF0079, ATPase
P9301_18211	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
P9301_18221	ENOG4105CJW	magnesium transporter
P9301_18261	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
P9301_18271	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
P9301_18281	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
P9301_18291	ENOG4105D7W	serine acetyltransferase
P9301_18301	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
P9301_18331	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
P9301_18351	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
P9301_18391	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
P9301_18411	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
P9301_18431	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
P9301_18441	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
P9301_18451	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
P9301_18461	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
P9301_18471	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
P9301_18481	ENOG4105C6E	dna polymerase iii
P9301_18491	ENOG4105CND	Glycosyl transferase, family 2
P9301_18501	ENOG4105JFG	SpoIID LytB domain protein
P9301_18511	ENOG41084A0	50s ribosomal protein L35
P9301_18521	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
P9301_18541	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
P9301_18551	ENOG4105CMR	udp-glucose 4-epimerase
P9301_18561	ENOG4105BZF	Glycosyl transferase (Group 1
P9301_18591	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
P9301_18601	ENOG4105CXI	aluminum resistance protein
P9301_18631	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
P9301_18641	ENOG4105CDU	Replicative dna helicase
P9301_18641	ENOG4105CDU	Replicative dna helicase
P9301_18651	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
P9301_18731	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
P9301_18751	ENOG4105DXN	mazG family
P9301_18761	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
P9301_18771	ENOG4105CYW	agmatinase
P9301_18781	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
P9301_18791	ENOG4105C9M	aspartyl-trna synthetase
P9301_18801	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
P9301_18811	ENOG4107U96	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
P9301_18821	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
P9301_18871	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
P9301_18881	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
P9301_18901	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
P9301_18921	ENOG4105CMQ	Chloride channel
P9301_18951	ENOG4105CFG	Acts as a chaperone (By similarity)
P9301_18961	ENOG4105E2X	shikimate dehydrogenase
P9301_18971	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
P9301_18981	ENOG4105CDH	Citrulline--aspartate ligase
P9301_19001	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
P9301_19011	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
P9301_tRNALeuVIMSS1309171	ENOG4105C8Y	Acetylornithine aminotransferase