locus-tag	class	description
GO498_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GO498_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GO498_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GO498_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GO498_00025	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GO498_00030	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GO498_00035	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GO498_00055	ENOG4105DSJ	YicC domain protein
GO498_00060	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GO498_00065	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GO498_00070	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GO498_00075	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GO498_00080	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GO498_00085	ENOG4105W5Q	DNA repair protein (RadC
GO498_00090	ENOG4105KDC	50s ribosomal protein l28
GO498_00095	ENOG4105W0E	50S ribosomal protein L33
GO498_00100	ENOG4105CPK	Glycosyl transferase (Group 1
GO498_00110	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GO498_00120	ENOG4108FRV	O-antigen ligase
GO498_00125	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GO498_00130	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GO498_00140	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GO498_00145	ENOG4105DKP	glycosyl transferase, family 9
GO498_00150	ENOG4107SBE	Glycosyl transferase (Group 1
GO498_00155	ENOG4105CPK	Glycosyl transferase (Group 1
GO498_00165	ENOG4105DKP	glycosyl transferase, family 9
GO498_00175	ENOG4105D16	lipopolysaccharide heptosyltransferase i
GO498_00180	ENOG4105XA0	heptosyltransferase ii
GO498_00185	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GO498_00190	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GO498_00195	ENOG4105CPQ	Dehydrogenase
GO498_00200	ENOG4105PXI	polysaccharide deacetylase
GO498_00205	ENOG41063SB	peptidase
GO498_00210	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GO498_00220	ENOG4107YZP	Rhodanese domain protein
GO498_00225	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GO498_00235	ENOG4105D7W	serine acetyltransferase
GO498_00240	ENOG4105D7W	serine acetyltransferase
GO498_00245	ENOG4107S6X	Glycosyl transferase, family 2
GO498_00250	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GO498_00270	ENOG4105K64	Glycosyl transferase, family 2
GO498_00290	ENOG4105K64	Glycosyl transferase, family 2
GO498_00295	ENOG4105E0F	Histidine kinase
GO498_00300	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GO498_00305	ENOG4105FMW	periplasmic
GO498_00310	ENOG4108J6E	Pfam:Phage_integr_N
GO498_00355	ENOG4105DFE	Dna adenine methylase
GO498_00365	ENOG4105VZ1	Replication Protein
GO498_00380	ENOG4105ED4	portal protein
GO498_00465	ENOG4105UZW	Tail fiber assembly protein
GO498_00505	ENOG4105ZTC	transcriptional activator, Ogr delta
GO498_00510	ENOG4105UPP	uncharacterized protein ydcA
GO498_00520	ENOG4105DIJ	Phosphoethanolamine transferase
GO498_00525	ENOG4105CHR	reductase
GO498_00530	ENOG4105CTQ	phosphohexokinase
GO498_00535	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
GO498_00540	ENOG4105CP7	Triose-phosphate isomerase
GO498_00545	ENOG4105EBK	exported protein
GO498_00550	ENOG4108VTS	Membrane
GO498_00555	ENOG4105DP0	ferredoxin-NADP reductase
GO498_00560	ENOG4105E5M	Multidrug resistance protein D
GO498_00565	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GO498_00570	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GO498_00575	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GO498_00580	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GO498_00585	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GO498_00590	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GO498_00595	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GO498_00600	ENOG41063M6	Cell Division Protein
GO498_00605	ENOG4105ETE	Transcriptional regulator (LacI family
GO498_00610	ENOG4105C25	Primosomal protein n'
GO498_00615	ENOG41082DI	50s ribosomal protein l31
GO498_00620	ENOG4105EUP	HipA domain protein
GO498_00625	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
GO498_00630	ENOG4105C28	cystathionine
GO498_00635	ENOG4105CFH	Aspartokinase
GO498_00640	ENOG4108TEB	UPF0114 protein
GO498_00650	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GO498_00655	ENOG4105K64	Glycosyl transferase, family 2
GO498_00660	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GO498_00665	ENOG4105CSH	Transporter
GO498_00670	ENOG4107R11	Transcriptional regulator
GO498_00690	ENOG4105C7K	acetolactate synthase
GO498_00695	ENOG4105CWC	Acetylornithine deacetylase
GO498_00700	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GO498_00705	ENOG4105CAS	nag kinase
GO498_00710	ENOG4105CDH	Citrulline--aspartate ligase
GO498_00715	ENOG4105CH7	arginosuccinase
GO498_00720	ENOG4105C5Q	Transcriptional regulator
GO498_00725	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
GO498_00735	ENOG4108Y73	Membrane
GO498_00740	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
GO498_00745	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GO498_00750	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GO498_00785	ENOG4105D4A	Cell wall formation (By similarity)
GO498_00790	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GO498_00795	ENOG4105CS9	pantothenic acid kinase
GO498_00825	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GO498_00845	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GO498_00850	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GO498_00855	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GO498_00860	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GO498_00865	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GO498_00870	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GO498_00875	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GO498_00880	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GO498_00885	ENOG41083MP	50s ribosomal protein l29
GO498_00890	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GO498_00895	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GO498_00900	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GO498_00905	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GO498_00910	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GO498_00915	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GO498_00920	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GO498_00925	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GO498_00930	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GO498_00935	ENOG4105VPB	50S ribosomal protein L30
GO498_00940	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GO498_00945	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GO498_00950	ENOG41067V7	50S ribosomal protein L36
GO498_00955	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GO498_00960	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GO498_00965	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GO498_00975	ENOG4108ZT0	50S ribosomal protein l17
GO498_00980	ENOG4105W1Y	Transcriptional regulator
GO498_00985	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
GO498_00990	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GO498_00995	ENOG4105C1A	potassium transporter peripheral membrane
GO498_01000	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GO498_01005	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GO498_01010	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GO498_01015	ENOG4105C79	DNA protecting protein DprA
GO498_01020	ENOG4108WI1	Dna topoisomerase
GO498_01025	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GO498_01030	ENOG4105E2X	shikimate dehydrogenase
GO498_01035	ENOG4105SG3	Protein of unknown function (DUF1488)
GO498_01040	ENOG4108Z0R	Transferase
GO498_01080	ENOG4105CVI	Transcriptional regulator
GO498_01085	ENOG4108WFC	UPF0438 protein yifE
GO498_01090	ENOG4105C0P	Mg chelatase subunit ChlI
GO498_01105	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
GO498_01110	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GO498_01115	ENOG4105C01	Dihydroxy-acid dehydratase
GO498_01120	ENOG4105C7B	Threonine dehydratase
GO498_01125	ENOG4105EMY	transcriptional regulator
GO498_01130	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GO498_01135	ENOG4105VXN	addiction module toxin, RelE StbE family
GO498_01145	ENOG4105C4R	Atp-dependent dna helicase
GO498_01150	ENOG4105C9X	ppx gppa phosphatase
GO498_01155	ENOG4105C1J	atp-dependent rna helicase
GO498_01160	ENOG4105K63	Thioredoxin
GO498_01170	ENOG4105ESV	Glycosyl transferase, family 4
GO498_01175	ENOG4105SFE	lipopolysaccharide biosynthesis protein
GO498_01180	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GO498_01185	ENOG4108IJ1	Dehydrogenase
GO498_01190	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GO498_01195	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GO498_01200	ENOG4108WJ1	acetyltransferase
GO498_01205	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GO498_01210	ENOG4105EGZ	biosynthesis protein
GO498_01215	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
GO498_01220	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
GO498_01225	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
GO498_01255	ENOG410601J	HemY protein
GO498_01260	ENOG4105ECF	c-methyltransferase
GO498_01270	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GO498_01275	ENOG4107T0K	Adenylate cyclase
GO498_01280	ENOG4105XQ6	frataxin-like protein
GO498_01285	ENOG4105S7Z	(LipO)protein
GO498_01290	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GO498_01295	ENOG4105CT0	Protein of unknown function, DUF484
GO498_01300	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GO498_01305	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GO498_01310	ENOG4105C4R	Atp-dependent dna helicase
GO498_01320	ENOG4105FR1	rard protein
GO498_01325	ENOG4108VUY	thioesterase Superfamily protein
GO498_01330	ENOG4105HDD	phospholipase
GO498_01335	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GO498_01340	ENOG4108EUD	Lysophospholipase
GO498_01345	ENOG4105DQF	Hydrolase
GO498_01355	ENOG4105CW0	outer membrane usher protein
GO498_01360	ENOG4108AF8	Chaperone
GO498_01365	ENOG4108S54	Fimbrial protein
GO498_01375	ENOG4105EGS	Mechanosensitive ion channel
GO498_01380	ENOG4105DJ4	phosphatidylserine decarboxylase
GO498_01385	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GO498_01390	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GO498_01420	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GO498_01425	ENOG4105K8N	protein family UPF0079, ATPase
GO498_01430	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GO498_01435	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GO498_01440	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GO498_01445	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GO498_01450	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GO498_01455	ENOG4107QJR	hflk protein
GO498_01460	ENOG4105EPW	hflc protein
GO498_01465	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GO498_01470	ENOG4105KPV	Transcriptional regulator
GO498_01475	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GO498_01480	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GO498_01485	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GO498_01490	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
GO498_01495	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GO498_01500	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GO498_01505	ENOG4105FHY	Opacity-associated protein A
GO498_01510	ENOG4105NRA	50s ribosomal protein l31 type b
GO498_01515	ENOG4105YK5	50S ribosomal protein L36
GO498_01520	ENOG4108MEK	Metal-binding protein YodA
GO498_01530	ENOG4105D7V	transposase
GO498_01535	ENOG4105C26	Dehydrogenase
GO498_01540	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GO498_01545	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GO498_01550	ENOG4108UUE	Transcriptional regulator
GO498_01555	ENOG41061GZ	Protein of unknown function (DUF1107)
GO498_01560	ENOG4105C37	(CBS) domain
GO498_01565	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GO498_01570	ENOG4105CFU	surface antigen
GO498_01575	ENOG4105MA0	exported protein
GO498_01580	ENOG4108ZHD	aig2 family
GO498_01600	ENOG4105F0N	pyrophosphate phospho-hydrolase
GO498_01605	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GO498_01610	ENOG4105DFU	Cell wall formation (By similarity)
GO498_01615	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GO498_01620	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GO498_01625	ENOG4105HVQ	Regulatory factor of maltose metabolism
GO498_01640	ENOG4105EAH	synthase
GO498_01645	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GO498_01650	ENOG4105K46	50S ribosomal protein l27
GO498_01655	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GO498_01660	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GO498_01665	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GO498_01670	ENOG4105HBR	Rna-binding protein
GO498_01675	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GO498_01680	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GO498_01685	ENOG4105EEI	dihydropteroate synthase
GO498_01690	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GO498_01710	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GO498_01715	ENOG4105CHV	Transcription elongation factor NusA
GO498_01720	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GO498_01725	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GO498_01730	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GO498_01735	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GO498_01740	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GO498_01750	ENOG4105C1J	atp-dependent rna helicase
GO498_01755	ENOG4105WWK	YheO domain protein
GO498_01765	ENOG4105KME	endoribonuclease L-psp
GO498_01770	ENOG4105R9B	Major Facilitator
GO498_01790	ENOG4108NEV	two component transcriptional regulator, LytTR family
GO498_01795	ENOG4108HRK	Histidine kinase
GO498_01800	ENOG4105J12	Multidrug resistance protein mdtN
GO498_01815	ENOG4108RQP	Major type 1 subunit fimbrin
GO498_01820	ENOG4108NAE	Fimbrial chaperone protein
GO498_01825	ENOG4105CW0	outer membrane usher protein
GO498_01830	ENOG4108SQA	Fimbrial
GO498_01835	ENOG4108T65	Fimbrial
GO498_01840	ENOG4106PIH	fimbrial-like protein ydeQ
GO498_01845	ENOG4106RZ4	Peptidase U32
GO498_01850	ENOG4105CFP	Peptidase U32
GO498_01855	ENOG4105XPQ	lipid carrier protein
GO498_01860	ENOG4108YYD	acetyltransferase
GO498_01865	ENOG41082IR	Excinuclease ABC C subunit domain protein
GO498_01870	ENOG4105ZY9	UPF0379 protein ybiM
GO498_01890	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GO498_01895	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GO498_01905	ENOG4105KME	endoribonuclease L-psp
GO498_01910	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GO498_01915	ENOG4105CXT	aspartate transcarbamylase
GO498_01925	ENOG4105DBV	ornithine carbamoyltransferase
GO498_01935	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
GO498_01940	ENOG4105EUB	pirin domain protein
GO498_01945	ENOG4105VYH	
GO498_01950	ENOG4108MJ3	acetyltransferase
GO498_01955	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GO498_01960	ENOG4105MYG	DNA polymerase iii, chi subunit
GO498_01965	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GO498_01970	ENOG4108M8S	permease YjgP YjgQ family protein
GO498_01975	ENOG4108K5H	permease YjgP YjgQ family protein
GO498_01980	ENOG4107R6D	beta-lactam binding protein AmpH
GO498_01995	ENOG4107RRE	RNA-directed DNA polymerase
GO498_02035	ENOG4105D7V	transposase
GO498_02050	ENOG4108S2Y	peptide Chain Release factor
GO498_02060	ENOG4107FB0	transcriptional regulator DeoR family
GO498_02065	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GO498_02070	ENOG4108RVA	ribokinase
GO498_02075	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GO498_02085	ENOG4105HX0	Transcriptional regulator
GO498_02100	ENOG4105C7K	acetolactate synthase
GO498_02105	ENOG4105M71	acetolactate synthase 1 regulatory subunit
GO498_02125	ENOG4105C7N	Xanthine uracil vitamin C permease
GO498_02130	ENOG4108MK9	spermidine N(1)-acetyltransferase
GO498_02135	ENOG4105EEQ	Na H antiporter
GO498_02140	ENOG4105EMK	carboxylate amino acid amine transporter
GO498_02145	ENOG4105DZ2	Transcriptional regulator
GO498_02150	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GO498_02160	ENOG4105VP5	Bacterial protein of unknown function (DUF937)
GO498_02165	ENOG4108I5U	Uridine phosphorylase
GO498_02175	ENOG4108KF1	Membrane
GO498_02180	ENOG4105CGY	Dna recombination protein
GO498_02185	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GO498_02190	ENOG4105JC1	sterol-binding domain protein
GO498_02195	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GO498_02200	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GO498_02205	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GO498_02210	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GO498_02215	ENOG4105MDZ	Transcriptional activator rfaH
GO498_02220	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
GO498_02225	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GO498_02235	ENOG4105CHU	acetyl-coa acetyltransferase
GO498_02240	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GO498_02245	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
GO498_02250	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GO498_02255	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GO498_02260	ENOG4108RR8	protoporphyrinogen oxidase
GO498_02290	ENOG4105C5A	transporter
GO498_02295	ENOG4105E7W	lamb ycsf family protein
GO498_02300	ENOG4105P4J	Allophanate hydrolase, subunit 1
GO498_02305	ENOG4108JIK	carboxylase
GO498_02310	ENOG4105HF0	Membrane
GO498_02325	ENOG4105HEI	LysR family (Transcriptional regulator
GO498_02330	ENOG4105WH1	Two component transcriptional regulator luxr family
GO498_02335	ENOG4105BZU	Histidine kinase
GO498_02340	ENOG4105DQQ	Major facilitator superfamily MFS_1
GO498_02345	ENOG4105CRU	nitrate reductase, alpha subunit
GO498_02350	ENOG4108IUE	nitrate reductase beta subunit
GO498_02355	ENOG4105R3A	Nitrate reductase
GO498_02360	ENOG41076YT	nitrate reductase, gamma subunit
GO498_02370	ENOG4105DIJ	Phosphoethanolamine transferase
GO498_02385	ENOG4108JUA	Transcriptional regulator
GO498_02410	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GO498_02415	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GO498_02430	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GO498_02435	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GO498_02440	ENOG4105CXY	transporter
GO498_02445	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GO498_02455	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GO498_02465	ENOG4105EX9	Membrane
GO498_02475	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GO498_02485	ENOG4105D7V	transposase
GO498_02500	ENOG4105C59	p-type ATPase
GO498_02505	ENOG4107FS9	Membrane
GO498_02515	ENOG4105MG3	Membrane
GO498_02520	ENOG4106H78	methyltransferase
GO498_02525	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GO498_02530	ENOG4105CAK	Cell division ATP-binding protein ftsE
GO498_02535	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GO498_02540	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GO498_02545	ENOG4105BZW	Glycerate kinase
GO498_02550	ENOG4105U59	-acetyltransferase
GO498_02560	ENOG4108INS	Transcriptional regulator
GO498_02565	ENOG4108K0D	peptidase, M48
GO498_02570	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GO498_02575	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
GO498_02585	ENOG4105BZ7	extracellular solute-binding protein family 1
GO498_02590	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GO498_02595	ENOG4105DJ2	Major Facilitator Superfamily
GO498_02630	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GO498_02635	ENOG4108IA2	Sodium pantothenate symporter
GO498_02640	ENOG4105RG0	Membrane
GO498_02645	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GO498_02650	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GO498_02655	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GO498_02660	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
GO498_02665	ENOG4105DFF	Rod shape-determining protein mreb
GO498_02670	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GO498_02675	ENOG4105VQ7	Rod shape-determining protein MreD
GO498_02680	ENOG4108Z03	MAF-like protein
GO498_02685	ENOG4105C03	ribonuclease
GO498_02690	ENOG4105QD6	exported protein
GO498_02700	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GO498_02710	ENOG41067XF	inhibitor
GO498_02715	ENOG4105N42	UPF0307 protein
GO498_02720	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GO498_02725	ENOG4105NXH	GreA GreB family elongation factor
GO498_02730	ENOG41080Z8	PHOSPHOCARRIER protein
GO498_02735	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GO498_02740	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GO498_02745	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GO498_02750	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GO498_02755	ENOG4108IUZ	ABC transporter
GO498_02760	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GO498_02765	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
GO498_02770	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GO498_02775	ENOG4105C2X	Arabinose 5-phosphate isomerase
GO498_02780	ENOG4105FEU	K -dependent Na -Ca exchanger
GO498_02785	ENOG4105DHJ	ABC, transporter
GO498_02790	ENOG4105CY3	ABC transporter, permease
GO498_02795	ENOG4107PE3	Mammalian cell entry related domain protein
GO498_02800	ENOG4105E3I	toluene tolerance
GO498_02810	ENOG4105VFK	BolA family
GO498_02815	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GO498_02825	ENOG4105C0H	protease
GO498_02830	ENOG4105C0H	protease
GO498_02835	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
GO498_02840	ENOG4105D6Z	AFG1 family ATPase
GO498_02845	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GO498_02850	ENOG4108UJD	30S ribosomal protein S9
GO498_02855	ENOG4107MKT	Stringent starvation protein a
GO498_02860	ENOG4105KB2	stringent starvation protein b
GO498_02870	ENOG4105CH2	amidohydrolase
GO498_02880	ENOG4105BZ8	glutamate synthase
GO498_02885	ENOG4105CBC	glutamate synthase
GO498_02890	ENOG4105BZU	Histidine kinase
GO498_02895	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GO498_02900	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GO498_02905	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
GO498_02910	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GO498_02915	ENOG4108YZ9	Urea amidohydrolase subunit gamma
GO498_02920	ENOG4105KI2	Urea amidohydrolase subunit beta
GO498_02925	ENOG4105CQM	Urea amidohydrolase subunit alpha
GO498_02930	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
GO498_02935	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GO498_02940	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
GO498_02945	ENOG4105W4M	Transport-associated protein
GO498_02950	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GO498_02955	ENOG41082RQ	UPF0102 protein
GO498_02965	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GO498_02975	ENOG4108CNN	domain protein
GO498_02980	ENOG4105CWB	LysR family transcriptional Regulator
GO498_02985	ENOG4108VBZ	doxx family
GO498_02995	ENOG41090KG	Inner membrane protein YqjE
GO498_03000	ENOG4105NE1	Conserved Protein
GO498_03005	ENOG4106W5V	Membrane
GO498_03010	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GO498_03015	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GO498_03025	ENOG4107RAN	Peptidase, M16
GO498_03030	ENOG4105CQ0	ABC transporter
GO498_03035	ENOG4105PE1	Receptor
GO498_03045	ENOG4108SF5	RNA Polymerase
GO498_03055	ENOG4105C5H	ABC transporter
GO498_03060	ENOG4107SC1	transglycosylase
GO498_03065	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
GO498_03070	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GO498_03075	ENOG4105CVJ	phosphoglycerate mutase
GO498_03080	ENOG4105UEI	Transcriptional Regulator AraC Family
GO498_03085	ENOG4108RH0	Crea protein
GO498_03090	ENOG41065U4	response regulator
GO498_03100	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GO498_03115	ENOG4105D1Q	UPF0246 protein
GO498_03120	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GO498_03130	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GO498_03135	ENOG4105CFG	Acts as a chaperone (By similarity)
GO498_03140	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GO498_03145	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GO498_03150	ENOG41063Z6	transcriptional regulator, lysR family
GO498_03155	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GO498_03165	ENOG4105DTN	riboflavin biosynthesis protein ribF
GO498_03170	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GO498_03175	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GO498_03180	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GO498_03185	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GO498_03190	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GO498_03195	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GO498_03200	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GO498_03215	ENOG4105CV8	reductase
GO498_03220	ENOG4108I6A	alcohol dehydrogenase
GO498_03225	ENOG4108I0C	methyltransferase
GO498_03230	ENOG4108K81	inner membrane protein YghB
GO498_03235	ENOG4105C28	cystathionine
GO498_03240	ENOG4105CWK	Biopolymer transport protein, ExbB
GO498_03245	ENOG4108ZZF	transport protein (ExbD)
GO498_03250	ENOG4105E3S	small subunit
GO498_03255	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GO498_03260	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
GO498_03265	ENOG4105DPX	Hydrogenase, large subunit
GO498_03270	ENOG4108USZ	hydrogenase
GO498_03275	ENOG4108WGS	hydrogenase 2-specific chaperone
GO498_03280	ENOG4107RSS	Hydrogenase accessory protein HypB
GO498_03285	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
GO498_03290	ENOG4105CQS	hydrogenase expression formation protein HypD
GO498_03295	ENOG4105C45	hydrogenase expression formation protein (HypE)
GO498_03300	ENOG41066VF	YeeE YedE family protein
GO498_03305	ENOG4105KSU	Redox protein
GO498_03310	ENOG4105DH7	May be involved in recombination (By similarity)
GO498_03320	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GO498_03325	ENOG41083KI	ribonuclease, T2
GO498_03330	ENOG4105CGH	5'-nucleotidase
GO498_03345	ENOG4105EYH	Exonuclease
GO498_03350	ENOG4107RH8	nuclease SbcCD subunit D
GO498_03355	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GO498_03360	ENOG4105BZU	Histidine kinase
GO498_03365	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GO498_03410	ENOG4108NWD	Cytochrome
GO498_03415	ENOG4108393	oxidoreductase Fe-S subunit
GO498_03420	ENOG4105JVW	
GO498_03425	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
GO498_03430	ENOG4108PU5	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO498_03440	ENOG4105D3R	alkyl hydroperoxide reductase
GO498_03445	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
GO498_03450	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GO498_03455	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GO498_03460	ENOG4105VIE	preprotein translocase, subunit YajC
GO498_03465	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GO498_03470	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GO498_03475	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GO498_03480	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GO498_03485	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GO498_03490	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GO498_03495	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GO498_03500	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GO498_03515	ENOG4105ETE	Transcriptional regulator (LacI family
GO498_03520	ENOG4108RVA	ribokinase
GO498_03525	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GO498_03530	ENOG4105CNN	ABC, transporter
GO498_03535	ENOG4105C2J	ABC transporter
GO498_03540	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GO498_03545	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GO498_03550	ENOG4105CTB	Polyprenyl synthetase
GO498_03555	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GO498_03560	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GO498_03570	ENOG4107S0N	DJ-1 family
GO498_03575	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GO498_03580	ENOG4108VPT	UPF0234 protein
GO498_03585	ENOG4107RDB	Major Facilitator
GO498_03590	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GO498_03595	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GO498_03600	ENOG4105CCU	oxidase (Subunit III)
GO498_03605	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GO498_03610	ENOG4105E2S	oxidase) subunit II
GO498_03615	ENOG4108NFH	Sugar hydrolase
GO498_03620	ENOG4105C1J	atp-dependent rna helicase
GO498_03625	ENOG4105EYM	Major Facilitator superfamily
GO498_03630	ENOG4105IEY	(LipO)protein
GO498_03635	ENOG4105M85	Bola protein
GO498_03640	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GO498_03645	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GO498_03650	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GO498_03655	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GO498_03660	ENOG4105K70	DNA-binding protein
GO498_03665	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GO498_03670	ENOG4105KQC	Competence protein
GO498_03675	ENOG4108TGP	Thioesterase superfamily protein
GO498_03680	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GO498_03685	ENOG4108XM1	transcriptional regulator AsnC family
GO498_03690	ENOG4105BZ1	(ABC) transporter
GO498_03695	ENOG4105BZ1	(ABC) transporter
GO498_03700	ENOG4108YZA	Nitrogen regulatory protein pii
GO498_03705	ENOG4105BZU	Histidine kinase
GO498_03710	ENOG4105C29	acyl-CoA thioesterase
GO498_03720	ENOG4105KF5	hemolysin expression-modulating protein
GO498_03730	ENOG4105BZS	acriflavin resistance protein
GO498_03735	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GO498_03740	ENOG4108IG5	Transcriptional regulator
GO498_03745	ENOG41090EX	DsrE family
GO498_03750	ENOG4105EGS	Mechanosensitive ion channel
GO498_03765	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GO498_03770	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GO498_03775	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GO498_03780	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GO498_03785	ENOG4105D22	carbon starvation protein
GO498_03790	ENOG4105VCD	cytoplasmic protein
GO498_03795	ENOG4105CKI	cobalamin synthesis protein
GO498_03805	ENOG4105CEE	C4-dicarboxylate transporter
GO498_03810	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GO498_03820	ENOG4105UQX	Mate efflux family protein
GO498_03825	ENOG4105DGA	Diaminopimelate dehydrogenase
GO498_03835	ENOG4105EQN	UPF0261 protein
GO498_03865	ENOG4108ZRK	uncharacterized protein yacC
GO498_03870	ENOG4105E3B	Multicopper oxidase
GO498_03875	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GO498_03880	ENOG41077A9	carbonic anhydrase
GO498_03885	ENOG4105DA5	(ABC) transporter
GO498_03890	ENOG4105E3A	(ABC) transporter
GO498_03895	ENOG41079KZ	Major Facilitator Superfamily
GO498_03900	ENOG4105R71	cytoplasmic protein
GO498_03905	ENOG4105D0M	Protease HtpX homolog
GO498_03920	ENOG4105QAX	Iron-sulfur
GO498_03925	ENOG4108J2R	molybdopterin oxidoreductase
GO498_03935	ENOG4105DBE	peroxidase
GO498_03950	ENOG4105WP5	
GO498_03965	ENOG4105GMB	type VI secretion system effector, hcp1 family
GO498_03980	ENOG4106032	Glutathionylspermidine synthase
GO498_03985	ENOG4105W8I	Transcriptional regulator
GO498_03990	ENOG4105C6Z	Gluconate
GO498_03995	ENOG4105BZC	d-serine deaminase
GO498_04000	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GO498_04005	ENOG4107RCV	ABC transporter, permease
GO498_04010	ENOG4105C4Y	ABC transporter
GO498_04015	ENOG4105CXY	transporter
GO498_04020	ENOG4105BZU	Histidine kinase
GO498_04025	ENOG4108KX4	response regulator
GO498_04030	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GO498_04035	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GO498_04040	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GO498_04045	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GO498_04050	ENOG4105DJ0	Poly(A) Polymerase
GO498_04060	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GO498_04065	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GO498_04070	ENOG4105CQ7	ATP-dependent helicase
GO498_04075	ENOG4105BZ4	penicillin-binding protein
GO498_04080	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GO498_04085	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GO498_04095	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GO498_04105	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GO498_04110	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GO498_04115	ENOG4105DXN	mazG family
GO498_04125	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GO498_04130	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GO498_04135	ENOG4105C8P	)-transporter
GO498_04145	ENOG4105E9H	Lytic Murein transglycosylase
GO498_04150	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GO498_04155	ENOG4105D1A	Methyltransferase
GO498_04160	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GO498_04165	ENOG4107RZZ	dna polymerase iii epsilon subunit
GO498_04200	ENOG4105EHG	Permease protein
GO498_04205	ENOG4105E0A	ABC, transporter
GO498_04255	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GO498_04260	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GO498_04265	ENOG4105BZA	Phosphoglycerate kinase
GO498_04270	ENOG4105D2N	Aldolase
GO498_04275	ENOG4105YB8	TM2 domain containing protein
GO498_04280	ENOG4105DUX	Transporter
GO498_04295	ENOG4108V8F	Transcriptional regulator, MarR family
GO498_04300	ENOG4105C94	Transporter
GO498_04315	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GO498_04320	ENOG4105HMV	Fimbrial protein
GO498_04325	ENOG4106PG1	outer membrane usher protein
GO498_04330	ENOG4108FZ9	Chaperone
GO498_04335	ENOG4105UGQ	Fimbrial
GO498_04340	ENOG4105NEV	Fimbrial
GO498_04360	ENOG4108W9T	type 1 fimbriae regulatory protein
GO498_04365	ENOG4105HMV	Fimbrial protein
GO498_04370	ENOG4108ZJG	MrfB protein
GO498_04375	ENOG4106PG1	outer membrane usher protein
GO498_04380	ENOG4108FZ9	Chaperone
GO498_04395	ENOG4105H8W	Fimbrial protein
GO498_04410	ENOG4105CFC	Transporter
GO498_04415	ENOG4105VTS	DnaJ-like, subfamily C
GO498_04425	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GO498_04430	ENOG4105DFG	type I secretion outer membrane protein
GO498_04435	ENOG4107QZV	Type I secretion membrane fusion protein
GO498_04440	ENOG4108JJ6	Type I secretion system ATPase
GO498_04445	ENOG4105QNJ	serralysin (EC 3.4.24.40)
GO498_04480	ENOG4107URF	beta-phospho-glucomutase
GO498_04485	ENOG4105C71	hydrolase family 65, central catalytic
GO498_04490	ENOG4105C5Y	PTS System
GO498_04495	ENOG4105D4X	repressor
GO498_04525	ENOG4106PG1	outer membrane usher protein
GO498_04530	ENOG4106P2F	Pfam:Pili_assembly_C
GO498_04585	ENOG4108JJA	ABC, transporter
GO498_04595	ENOG4108WUH	Transcriptional regulator, TetR family
GO498_04600	ENOG4105D5Q	Arginine ornithine antiporter
GO498_04605	ENOG4105CXN	decarboxylase
GO498_04645	ENOG4105CDU	Replicative dna helicase
GO498_04685	ENOG4108IYH	Dna topoisomerase
GO498_04825	ENOG4105D5K	Hemolysin activator protein
GO498_04830	ENOG4105CKT	filamentous hemagglutinin
GO498_04945	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GO498_04950	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GO498_04955	ENOG4105CEN	a g-specific adenine glycosylase
GO498_04965	ENOG41090ED	Protein with unknown function (DUF469)
GO498_04970	ENOG4105CSV	Glutaminase
GO498_04975	ENOG4105K33	Periplasmic Protein
GO498_04985	ENOG4105CSA	Coproporphyrinogen iii oxidase
GO498_04990	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GO498_04995	ENOG4108VIA	integral membrane protein
GO498_05000	ENOG4105II7	pyrroline-5-carboxylate reductase
GO498_05005	ENOG4105DFA	alanine racemase domain protein
GO498_05010	ENOG4105CZX	twitching motility protein
GO498_05015	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GO498_05020	ENOG4108UJU	UPF0301 protein
GO498_05025	ENOG4105D7Z	glutathione synthase
GO498_05030	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GO498_05050	ENOG4105EJC	lysr family transcriptional regulator
GO498_05055	ENOG4105RQF	LysR family Transcriptional regulator
GO498_05060	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GO498_05065	ENOG4107QPN	acyl-Coa dehydrogenase
GO498_05070	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GO498_05075	ENOG4105E7A	Glutamine amidotransferase
GO498_05080	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
GO498_05085	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GO498_05090	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GO498_05095	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GO498_05100	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GO498_05105	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GO498_05110	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GO498_05115	ENOG4105CJ2	(LipO)protein
GO498_05125	ENOG4105VDW	Csbd family
GO498_05135	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GO498_05140	ENOG4105E0K	tonB-dependent siderophore receptor
GO498_05145	ENOG4105CIN	aminoacyl-histidine dipeptidase
GO498_05150	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GO498_05155	ENOG4105V1F	Fermentation respiration switch protein
GO498_05165	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GO498_05170	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GO498_05175	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GO498_05180	ENOG4105CEY	Amp-dependent synthetase and ligase
GO498_05185	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
GO498_05190	ENOG4107TH8	cina domain protein
GO498_05195	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GO498_05200	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GO498_05205	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GO498_05235	ENOG4105D9M	gamma-glutamylcysteine synthetase
GO498_05240	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GO498_05245	ENOG4108JU6	CBS domain protein
GO498_05250	ENOG4106KVJ	cytochrome C assembly protein
GO498_05255	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GO498_05260	ENOG4105K5M	30s ribosomal protein S16
GO498_05270	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GO498_05275	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GO498_05280	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GO498_05290	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GO498_05295	ENOG4105CQC	Prephenate dehydratase
GO498_05300	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GO498_05305	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO498_05310	ENOG4105C34	Pseudouridine synthase
GO498_05315	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GO498_05320	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GO498_05350	ENOG4105T42	(LipO)protein
GO498_05355	ENOG4105JIM	Phosphatidylserine synthase
GO498_05360	ENOG4105CD5	CoA-binding domain protein
GO498_05365	ENOG4106IUH	DTW domain containing protein
GO498_05370	ENOG4105Z6G	Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is
GO498_05375	ENOG4105EIB	trna rrna methyltransferase
GO498_05380	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GO498_05385	ENOG4105CW7	secretion protein, HlyD family
GO498_05395	ENOG4105C6X	Major Facilitator
GO498_05400	ENOG4108UAU	isochorismatase
GO498_05405	ENOG4105NTK	Transcriptional repressor Mpra
GO498_05410	ENOG4105EQ0	Major Facilitator superfamily
GO498_05415	ENOG4105X58	receptor
GO498_05420	ENOG4105GIJ	Glycine betaine
GO498_05425	ENOG4108HQS	Glycine betaine
GO498_05430	ENOG4108IJ7	Glycine betaine
GO498_05445	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
GO498_05455	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GO498_05460	ENOG4105VEQ	Cold shock protein
GO498_05470	ENOG4107Z6W	Protein CrcB homolog
GO498_05475	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GO498_05480	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GO498_05485	ENOG4108Z43	UPF0250 protein
GO498_05490	ENOG4105DZ1	carboxypeptidase
GO498_05495	ENOG4105K6T	rare lipoprotein A
GO498_05500	ENOG4105CNI	cell division protein FtsW
GO498_05505	ENOG4105CJN	penicillin-binding protein
GO498_05510	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GO498_05515	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GO498_05525	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GO498_05530	ENOG4105DJF	DNA polymerase III, delta' subunit
GO498_05535	ENOG4108U2H	Rare lipoprotein B
GO498_05540	ENOG4105C8T	Leucyl-tRNA synthetase
GO498_05545	ENOG4105CDA	abc transporter atp-binding protein
GO498_05550	ENOG4105DRP	amino acid AbC transporter
GO498_05555	ENOG4105EAD	ABC transporter
GO498_05560	ENOG4107RP9	extracellular solute-binding protein, family 3
GO498_05580	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GO498_05590	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GO498_05595	ENOG4108JU5	Magnesium and cobalt efflux protein
GO498_05600	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GO498_05605	ENOG4105C9A	Phoh family
GO498_05610	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GO498_05615	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GO498_05620	ENOG4105C4W	S-formylglutathione hydrolase
GO498_05670	ENOG4105E2R	ROK family
GO498_05675	ENOG4105CE4	GlcNAc 6-P deacetylase
GO498_05680	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GO498_05685	ENOG4105CI1	PTS System
GO498_05690	ENOG4108I1J	Integrase
GO498_05715	ENOG4108UUM	single-stranded DNA-binding protein
GO498_05780	ENOG4105CDU	Replicative dna helicase
GO498_05795	ENOG4105RWQ	Protein of unknown function (DUF1364)
GO498_05810	ENOG4105R3P	Inner membrane protein yagU
GO498_05825	ENOG4105KUS	lysozyme
GO498_06020	ENOG4105MPK	DNA polymerase III subunit theta
GO498_06025	ENOG4105CX6	glutaminyL-tRNA synthetase
GO498_06040	ENOG41090R7	Ferric uptake
GO498_06045	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GO498_06050	ENOG4105NNH	LexA regulated protein
GO498_06055	ENOG4105EV9	Alpha Beta Hydrolase
GO498_06060	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GO498_06065	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GO498_06070	ENOG4108W15	Protein of unknown function (DUF1456)
GO498_06075	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
GO498_06085	ENOG4105XIQ	Protein of unknown function (DUF2517)
GO498_06090	ENOG4107QNR	UPF0135 protein
GO498_06100	ENOG4105DEG	Vwa containing coxe family protein
GO498_06105	ENOG4105RD5	
GO498_06110	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
GO498_06120	ENOG4105C2C	drug resistance transporter, Bcr CflA
GO498_06130	ENOG4105BZN	citrate synthase
GO498_06135	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GO498_06140	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GO498_06150	ENOG4105E33	succinate dehydrogenase
GO498_06155	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GO498_06160	ENOG4105C7S	Dehydrogenase
GO498_06165	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GO498_06170	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GO498_06175	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GO498_06180	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GO498_06190	ENOG4105KJB	cyd operon protein YbgE
GO498_06195	ENOG4105HEI	LysR family (Transcriptional regulator
GO498_06200	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GO498_06210	ENOG4107YD3	Thioesterase
GO498_06215	ENOG4105E02	MotA TolQ exbB proton channel
GO498_06220	ENOG4105M8F	Biopolymer transport protein exbD tolR
GO498_06225	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
GO498_06230	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GO498_06235	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GO498_06240	ENOG4105UFD	tol-pal system protein YbgF
GO498_06260	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GO498_06265	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GO498_06270	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GO498_06275	ENOG4105DKW	ABC transporter
GO498_06280	ENOG4105D5K	Hemolysin activator protein
GO498_06310	ENOG4105F4R	Transcriptional regulator mode
GO498_06315	ENOG410680R	Protein of unknown function (DUF2592)
GO498_06320	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GO498_06325	ENOG4105E0C	molybdate abc transporter
GO498_06330	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GO498_06335	ENOG4108K4B	hydrolase
GO498_06340	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
GO498_06345	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GO498_06350	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GO498_06355	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GO498_06360	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GO498_06365	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GO498_06370	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GO498_06385	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GO498_06390	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GO498_06395	ENOG4105M00	molybdopterin converting factor, subunit 1
GO498_06400	ENOG4108ZAF	Molybdopterin
GO498_06405	ENOG4105HFZ	Membrane
GO498_06410	ENOG4107QWP	ABC-2 type transporter
GO498_06415	ENOG4107QWP	ABC-2 type transporter
GO498_06420	ENOG4105CJ1	ABC, transporter
GO498_06430	ENOG4107MVR	Transcriptional regulator
GO498_06435	ENOG4105C1J	atp-dependent rna helicase
GO498_06440	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GO498_06450	ENOG4105KHC	sulfurtransferase
GO498_06460	ENOG4105CEE	C4-dicarboxylate transporter
GO498_06470	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
GO498_06475	ENOG4108PGP	mmge prpd family protein
GO498_06480	ENOG4107NQ8	LysR family Transcriptional regulator
GO498_06485	ENOG4105DVT	helicase
GO498_06500	ENOG4108URH	decarboxylase
GO498_06515	ENOG4105D06	uba thif-type nad fad binding protein
GO498_06520	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GO498_06525	ENOG4105CBP	Major Facilitator
GO498_06530	ENOG4105EUJ	GTP cyclohydrolase i
GO498_06535	ENOG4105DHF	Membrane
GO498_06540	ENOG4107GZ4	SanA protein
GO498_06545	ENOG4107R1I	NAD-dependent malic enzyme
GO498_06550	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
GO498_06555	ENOG41067MG	lrgb family
GO498_06560	ENOG4105VAW	lrga family
GO498_06565	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GO498_06570	ENOG4105D1F	ATP-binding protein
GO498_06575	ENOG4105DBI	uridine monophosphokinase
GO498_06580	ENOG4105DHP	deoxycytidine triphosphate deaminase
GO498_06585	ENOG4108GAE	asmA family
GO498_06590	ENOG4105CEE	C4-dicarboxylate transporter
GO498_06595	ENOG4105EE5	Membrane protein terC
GO498_06600	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GO498_06605	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
GO498_06610	ENOG4105C0A	alcohol dehydrogenase
GO498_06615	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GO498_06620	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GO498_06625	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GO498_06630	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GO498_06635	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GO498_06645	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GO498_06650	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GO498_06655	ENOG4108535	NAD dependent epimerase/dehydratase family
GO498_06660	ENOG4108TGY	Glutathione S-transferase
GO498_06665	ENOG4105DZ1	carboxypeptidase
GO498_06670	ENOG4105CKU	formyltetrahydrofolate synthetase
GO498_06675	ENOG4105EJQ	L-serine dehydratase
GO498_06680	ENOG4105C44	Serine transporter
GO498_06685	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
GO498_06690	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GO498_06695	ENOG41090BQ	Glutaredoxin
GO498_06700	ENOG4105X20	member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress
GO498_06705	ENOG4108RMJ	sensory transduction regulator
GO498_06710	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
GO498_06715	ENOG4105DMR	ABC, transporter
GO498_06720	ENOG4105GBT	ABC transporter
GO498_06725	ENOG4106PMH	Extracellular solute-binding protein family 3
GO498_06730	ENOG4105E5Z	arginine transporter ATP-binding subunit
GO498_06735	ENOG4105CGD	Nad-dependent epimerase dehydratase
GO498_06740	ENOG4105DWU	Membrane
GO498_06745	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
GO498_06750	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GO498_06755	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GO498_06760	ENOG4105VEQ	Cold shock protein
GO498_06765	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GO498_06770	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GO498_06775	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GO498_06780	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GO498_06785	ENOG4108JJ8	(ABC) transporter
GO498_06790	ENOG4108JJ9	ABC, transporter
GO498_06795	ENOG4105C3M	thioredoxin reductase
GO498_06800	ENOG4105EW9	transcriptional regulator AsnC family
GO498_06805	ENOG4105CNU	cell division protein FtsK
GO498_06810	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GO498_06815	ENOG4105D1H	recombination factor protein RarA
GO498_06820	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GO498_06830	ENOG4105DG4	malate L-lactate dehydrogenase
GO498_06840	ENOG4105F1A	Pyruvate formate-lyase
GO498_06845	ENOG4105C6N	Formate acetyltransferase
GO498_06850	ENOG4105TMB	Formate nitrite transporter
GO498_06855	ENOG4105DDY	UPF0142 protein ycaO
GO498_06860	ENOG4105HDK	L-asparaginase
GO498_06865	ENOG4105CKT	filamentous hemagglutinin
GO498_06875	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GO498_06880	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GO498_06885	ENOG4105CAT	Cytidine monophosphate kinase
GO498_06890	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GO498_06895	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GO498_06900	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GO498_06905	ENOG4105BZ1	(ABC) transporter
GO498_06910	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GO498_06920	ENOG4105W49	UPF0434 protein
GO498_06925	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GO498_06930	ENOG4107S90	membrAne
GO498_06935	ENOG4106371	Methyltransferase
GO498_06940	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
GO498_06945	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
GO498_06950	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
GO498_06955	ENOG4108UY2	Chloramphenicol acetyltransferase
GO498_06960	ENOG4105F0S	class B acid phosphatase
GO498_06965	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GO498_06970	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GO498_06975	ENOG4105C5X	domain protein
GO498_06980	ENOG4105GMB	type VI secretion system effector, hcp1 family
GO498_07015	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GO498_07065	ENOG4108WC9	type VI secretion system effector, hcp1 family
GO498_07070	ENOG4105CS6	Rhs element vgr protein
GO498_07170	ENOG4105CGF	Aromatic amino acid aminotransferase
GO498_07175	ENOG4105FCK	Membrane
GO498_07180	ENOG4105C5S	asparaginyl-tRNA synthetase
GO498_07190	ENOG4107RH7	Nicotinate phosphoribosyltransferase
GO498_07195	ENOG4105CD8	aminopeptidase N
GO498_07205	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GO498_07210	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
GO498_07215	ENOG4105QVC	MOSC domain-containing protein
GO498_07220	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GO498_07225	ENOG4105C5H	ABC transporter
GO498_07230	ENOG4105F1S	paraquat-inducible protein a
GO498_07235	ENOG4105DY2	Paraquat-inducible protein b
GO498_07240	ENOG4108Q2G	(LipO)protein
GO498_07250	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
GO498_07255	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GO498_07260	ENOG4105DAN	ATP-dependent protease
GO498_07265	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
GO498_07285	ENOG4105EM2	membrane
GO498_07290	ENOG41088T4	Helicase IV
GO498_07295	ENOG4108Z5K	methylglyoxal synthase
GO498_07300	ENOG4105K4P	CoA-binding domain protein
GO498_07305	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
GO498_07310	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GO498_07315	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GO498_07335	ENOG4108YS1	cytoplasmic protein
GO498_07345	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
GO498_07350	ENOG4105HEI	LysR family (Transcriptional regulator
GO498_07355	ENOG4105CV8	reductase
GO498_07365	ENOG4105UEI	Transcriptional Regulator AraC Family
GO498_07380	ENOG4105VEQ	Cold shock protein
GO498_07385	ENOG4105D1S	lipid A biosynthesis
GO498_07400	ENOG4105DTA	methyltransferase
GO498_07415	ENOG410829K	Lysine exporter protein (Lyse ygga)
GO498_07490	ENOG4107XU6	Glycosyl transferase (Group 1
GO498_07505	ENOG4105E68	Sulfatase
GO498_07510	ENOG4105PAN	UPF0352 protein
GO498_07515	ENOG4106V8H	Nucleoid-associated protein
GO498_07520	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GO498_07525	ENOG4105CFI	type iii restriction protein res subunit
GO498_07530	ENOG4105I08	Pseudouridine synthase
GO498_07535	ENOG4105C2C	drug resistance transporter, Bcr CflA
GO498_07545	ENOG4107TT5	NLP P60 protein
GO498_07550	ENOG41076MN	Phosphoesterase, PA-phosphatase related
GO498_07565	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GO498_07580	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GO498_07585	ENOG4105HMI	Membrane
GO498_07590	ENOG4105DUM	transcriptional regulator, lysR family
GO498_07595	ENOG4108IQI	permease
GO498_07600	ENOG4105D05	Receptor
GO498_07610	ENOG4105CUB	amino acid
GO498_07620	ENOG4107RA9	decarboxylase
GO498_07625	ENOG4105C5Q	Transcriptional regulator
GO498_07630	ENOG4105CXG	d-lactate dehydrogenase
GO498_07640	ENOG4105CJB	Exodeoxyribonuclease I
GO498_07645	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
GO498_07650	ENOG41090HJ	UPF0265 protein
GO498_07655	ENOG4107QQB	Ribonuclease E
GO498_07660	ENOG4105EI2	Pseudouridine synthase
GO498_07670	ENOG4108UHJ	MAF-like protein
GO498_07675	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GO498_07680	ENOG4105VGS	50s ribosomal protein l32
GO498_07685	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GO498_07690	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GO498_07695	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GO498_07700	ENOG4105CHR	reductase
GO498_07705	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GO498_07710	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GO498_07715	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
GO498_07720	ENOG4105HHA	aminodeoxychorismate lyase
GO498_07725	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GO498_07730	ENOG4107QRG	dna polymerase iii
GO498_07735	ENOG4105F8V	Hydrolase, tatD family
GO498_07740	ENOG4105K59	histidine triad (HIT) protein
GO498_07745	ENOG41090DQ	Lipoprotein
GO498_07750	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
GO498_07755	ENOG4108KN0	Choline kinase
GO498_07760	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
GO498_07765	ENOG4105D0Y	UPF0227 protein
GO498_07770	ENOG4105CEP	NADH dehydrogenase
GO498_07775	ENOG4107MBR	17 kDa surface antigen
GO498_07780	ENOG4108JA2	transcriptioN-repair coupling factor
GO498_07785	ENOG4105D60	lipoprotein releasing system transmembrane protein
GO498_07795	ENOG4105D60	lipoprotein releasing system transmembrane protein
GO498_07800	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GO498_07815	ENOG4105EZE	Cupin 4 family protein
GO498_07820	ENOG4105IFJ	Histidine kinase
GO498_07825	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GO498_07830	ENOG4107QTF	adenylosuccinate lyase
GO498_07835	ENOG41075W9	High frequency lysogenization protein HflD homolog
GO498_07840	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GO498_07850	ENOG4108R99	pseudouridine synthase
GO498_07855	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GO498_07895	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GO498_07910	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GO498_07925	ENOG4105VEQ	Cold shock protein
GO498_07930	ENOG4108ZNX	Heat shock protein
GO498_07940	ENOG4105KVH	Transcriptional regulator
GO498_07945	ENOG4105ECR	NmrA family
GO498_07955	ENOG4105DBI	uridine monophosphokinase
GO498_07970	ENOG4105GTN	ParB Domain Protein Nuclease
GO498_07975	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
GO498_07980	ENOG4108WF3	methyltransferase
GO498_07990	ENOG4107SEY	Conserved Protein
GO498_07995	ENOG4105Z2P	Protein of unknown function (DUF465)
GO498_08025	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GO498_08030	ENOG4105HRS	Antitermination protein
GO498_08040	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
GO498_08045	ENOG4108RS6	transposase
GO498_08050	ENOG4105D7V	transposase
GO498_08055	ENOG4107SSZ	Phosphatase
GO498_08070	ENOG4108RW8	Universal stress protein F
GO498_08075	ENOG41090A1	ferritin
GO498_08080	ENOG4105FXM	Copper resistance protein
GO498_08085	ENOG4108PNC	copper resistance
GO498_08090	ENOG4105NKT	exported protein
GO498_08100	ENOG4105DY2	Paraquat-inducible protein b
GO498_08105	ENOG4105H2K	paraquat-inducible protein a
GO498_08110	ENOG4108ZGC	gaf domain protein
GO498_08115	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
GO498_08120	ENOG4105CN1	protease
GO498_08130	ENOG4105D0M	Protease HtpX homolog
GO498_08135	ENOG4108ETY	sodium dicarboxylate symporter
GO498_08140	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
GO498_08145	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
GO498_08150	ENOG4107PN8	YfeABCD locus regulator
GO498_08155	ENOG4105FGM	Fructosamine kinase
GO498_08160	ENOG4105CC5	ABC transporter
GO498_08165	ENOG4105CC5	ABC transporter
GO498_08170	ENOG4105DIK	(ABC) transporter
GO498_08175	ENOG4105DSE	periplasmic solute binding protein
GO498_08195	ENOG4108Z7R	Chaperone CsaA
GO498_08205	ENOG4106PIH	fimbrial-like protein ydeQ
GO498_08210	ENOG4105C22	threonyL-tRNA synthetase
GO498_08215	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GO498_08220	ENOG41082NX	50s ribosomal protein l35
GO498_08225	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GO498_08235	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GO498_08240	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GO498_08245	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GO498_08250	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
GO498_08255	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
GO498_08260	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GO498_08265	ENOG4105CKK	Glycosyl transferase, family 2
GO498_08270	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GO498_08275	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GO498_08280	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GO498_08285	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
GO498_08290	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
GO498_08295	ENOG4108QBX	(LipO)protein
GO498_08300	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
GO498_08310	ENOG4105D5U	fad dependent oxidoreductase
GO498_08315	ENOG4107YCY	Transcriptional regulator
GO498_08330	ENOG4107ZTW	SNARE associated Golgi
GO498_08335	ENOG4105C7K	acetolactate synthase
GO498_08390	ENOG4105C3G	gtp-binding protein
GO498_08395	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GO498_08400	ENOG4105MGX	transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria
GO498_08405	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GO498_08410	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GO498_08415	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GO498_08420	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GO498_08425	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GO498_08430	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GO498_08435	ENOG41063JG	Transcriptional regulator
GO498_08440	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GO498_08445	ENOG4105N5T	Radical SAM Protein
GO498_08455	ENOG4105CHH	sulfate transporter
GO498_08465	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
GO498_08480	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
GO498_08490	ENOG4105EV4	Multidrug resistance protein mdtH
GO498_08495	ENOG4105D9U	N-acetyltransferase
GO498_08500	ENOG4105CJR	Integral membrane protein (MviN
GO498_08510	ENOG4105C75	arginyL-tRNA synthetase
GO498_08515	ENOG4106ZCM	YecM protein
GO498_08520	ENOG4106N3A	copper homeostasis protein cutc
GO498_08530	ENOG4105C5H	ABC transporter
GO498_08535	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GO498_08540	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GO498_08545	ENOG4105WJG	Glutathione
GO498_08550	ENOG4105C9M	aspartyl-trna synthetase
GO498_08555	ENOG4108TIT	dATP pyrophosphohydrolase
GO498_08560	ENOG4105CDY	transcriptional regulatory protein
GO498_08565	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GO498_08570	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GO498_08575	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GO498_08580	ENOG4108WC9	type VI secretion system effector, hcp1 family
GO498_08585	ENOG4105CS6	Rhs element vgr protein
GO498_08595	ENOG4105CNA	YD repeat protein
GO498_08620	ENOG4105CNA	YD repeat protein
GO498_08645	ENOG4105FAV	ABC, transporter
GO498_08650	ENOG4105FDK	ABC transporter
GO498_08655	ENOG4105NXV	High-affinity zinc uptake system protein
GO498_08660	ENOG4105DR5	peptidase
GO498_08665	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
GO498_08670	ENOG4105CA9	Pyruvate kinase
GO498_08675	ENOG4106KNT	transcriptional regulator
GO498_08680	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GO498_08685	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
GO498_08690	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
GO498_08695	ENOG4105CGD	Nad-dependent epimerase dehydratase
GO498_08700	ENOG4105M4H	endoribonuclease L-psp
GO498_08705	ENOG4105DVT	helicase
GO498_08710	ENOG41072GX	Peptidase M22 Glycoprotease
GO498_08715	ENOG4105Y4Z	Outer Membrane Lipoprotein
GO498_08720	ENOG4105CEY	Amp-dependent synthetase and ligase
GO498_08725	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GO498_08730	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GO498_08735	ENOG4107QMS	site-determining protein
GO498_08740	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GO498_08745	ENOG4105VNG	YcgL domain-containing protein
GO498_08750	ENOG4105CVE	Lytic murein transglycosylase
GO498_08755	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GO498_08760	ENOG4108ZZ3	UPF0260 protein
GO498_08765	ENOG4105C4B	ABC transporter, permease
GO498_08770	ENOG41083J0	(ABC) transporter
GO498_08780	ENOG4105UEI	Transcriptional Regulator AraC Family
GO498_08790	ENOG4105C8Q	Methyl-accepting chemotaxis
GO498_08795	ENOG4105C5I	Dehydrogenase
GO498_08800	ENOG4107H52	Dicarboxylate transport
GO498_08805	ENOG410689M	(LipO)protein
GO498_08810	ENOG4105WXT	Conserved Protein
GO498_08840	ENOG4105CQ7	ATP-dependent helicase
GO498_08855	ENOG4105CW0	outer membrane usher protein
GO498_08860	ENOG4108VCD	Chaperone
GO498_08870	ENOG4105D5Q	Arginine ornithine antiporter
GO498_08875	ENOG4105C5D	exported protein
GO498_08880	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GO498_08885	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GO498_08890	ENOG4105Q9Y	Universal stress protein
GO498_08895	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GO498_08900	ENOG4107QY8	reductase
GO498_08905	ENOG4105QAX	Iron-sulfur
GO498_08930	ENOG4105NTW	Transcriptional regulator
GO498_08940	ENOG4105D3R	alkyl hydroperoxide reductase
GO498_08945	ENOG4108JU3	Alkyl hydroperoxide reductase
GO498_09045	ENOG4105FYV	Amp nucleosidase
GO498_09050	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GO498_09055	ENOG4105D44	asparaginase
GO498_09060	ENOG4105D0S	secretion protein (HlyD
GO498_09065	ENOG4105CJ1	ABC, transporter
GO498_09070	ENOG4105CMI	transporter
GO498_09075	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GO498_09080	ENOG4105C08	Histidine kinase
GO498_09085	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
GO498_09095	ENOG4107KGK	dmso reductase anchor subunit
GO498_09100	ENOG4105QAX	Iron-sulfur
GO498_09105	ENOG4107QY8	reductase
GO498_09110	ENOG4105E98	transcriptional regulator DeoR family
GO498_09130	ENOG4105CMT	Dihydroxyacetone kinase
GO498_09140	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GO498_09150	ENOG4105KME	endoribonuclease L-psp
GO498_09175	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GO498_09180	ENOG4105V0I	UPF0267 protein
GO498_09185	ENOG4105C5H	ABC transporter
GO498_09190	ENOG4105CPF	Cell wall formation (By similarity)
GO498_09195	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GO498_09210	ENOG4105D01	(LipO)protein
GO498_09215	ENOG4105C28	cystathionine
GO498_09230	ENOG4105E5W	Transporter
GO498_09235	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GO498_09240	ENOG4105CBN	LysR family transcriptional regulator
GO498_09260	ENOG4105C5H	ABC transporter
GO498_09265	ENOG4108UPT	UPF0178 protein
GO498_09270	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GO498_09275	ENOG4105G2Y	Transcriptional regulator
GO498_09280	ENOG4105CNH	Multidrug resistance protein MdtL
GO498_09295	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
GO498_09305	ENOG4105J12	Multidrug resistance protein mdtN
GO498_09310	ENOG4108MI0	Resistance protein
GO498_09315	ENOG4105DFG	type I secretion outer membrane protein
GO498_09325	ENOG4105R8A	Heat shock protein
GO498_09330	ENOG4105C5W	Aldolase
GO498_09345	ENOG4105CMG	Carbohydrate kinase
GO498_09350	ENOG4105C93	Xylose Isomerase
GO498_09355	ENOG4105DFD	Na H antiporter
GO498_09360	ENOG4105CHM	Aminotransferase
GO498_09365	ENOG4105T16	Transcriptional regulator (AraC family)
GO498_09370	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GO498_09430	ENOG41061RM	osmotically inducible lipoprotein
GO498_09440	ENOG4105EMU	Dehydrogenase
GO498_09445	ENOG4105M5Q	UPF0482 protein
GO498_09455	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GO498_09460	ENOG4105DAG	ROK family
GO498_09465	ENOG4106NZI	LysR family Transcriptional regulator
GO498_09470	ENOG4105D94	Major Facilitator Superfamily
GO498_09475	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
GO498_09480	ENOG4105C9Q	fumarate hydratase class II
GO498_09485	ENOG4106J39	exported protein
GO498_09495	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GO498_09500	ENOG4105DHU	Bile acid
GO498_09505	ENOG4105D9R	oxidoreductase
GO498_09510	ENOG4105M9B	inner membrane protein ydgK
GO498_09515	ENOG4105DGN	Electron transport complex
GO498_09525	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
GO498_09535	ENOG4108UQQ	Electron transport complex
GO498_09545	ENOG4105CSM	endonuclease III
GO498_09550	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
GO498_09555	ENOG4108ZJT	translation initiation factor, Sui1
GO498_09560	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GO498_09565	ENOG4105CFV	Tetratricopeptide repeat protein
GO498_09570	ENOG4105Q4A	inner membrane protein yciS
GO498_09575	ENOG4105EYK	Phosphatidylglycerophosphatase B
GO498_09580	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GO498_09585	ENOG4105D01	(LipO)protein
GO498_09595	ENOG4107QM5	aconitate hydratase
GO498_09605	ENOG4107R11	Transcriptional regulator
GO498_09620	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GO498_09625	ENOG4105RKX	Protein of unknown function (DUF2498)
GO498_09630	ENOG4105ERU	peptidase
GO498_09635	ENOG4105UBK	short-chain dehydrogenase reductase
GO498_09640	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GO498_09650	ENOG4105FE9	pseudouridine synthase
GO498_09655	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GO498_09660	ENOG4105DB7	PHP domain protein
GO498_09665	ENOG4105CRQ	synthase (Component I)
GO498_09670	ENOG4105DDQ	anthranilate synthase
GO498_09675	ENOG4107QYG	anthranilate phosphoribosyltransferase
GO498_09680	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GO498_09685	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GO498_09690	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GO498_09700	ENOG4105EIF	outer membrane protein W
GO498_09705	ENOG4108S3I	UPF0259 membrane protein
GO498_09715	ENOG4107835	probably involved in intracellular septation (By similarity)
GO498_09720	ENOG4105NAU	thioesterase Superfamily protein
GO498_09735	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GO498_09745	ENOG4108T1M	outer membrane protein x
GO498_09750	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GO498_09770	ENOG4107RX3	Mg2 transporter protein cora family protein
GO498_09785	ENOG4107QSI	ABC, transporter
GO498_09790	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GO498_09805	ENOG4106K28	UPF0283 membrane protein
GO498_09810	ENOG4105CM6	amino acid regulated cytosolic protein
GO498_09820	ENOG4105FM1	phage shock protein C
GO498_09825	ENOG4105YYT	phage shock protein B
GO498_09830	ENOG41087YS	Phage shock protein A
GO498_09835	ENOG4105E51	psp operon transcriptional activator
GO498_09840	ENOG4108HIY	periplasmic
GO498_09845	ENOG4108I5W	peptide transport system, permease protein
GO498_09850	ENOG4108EU3	peptide transport system, permease
GO498_09855	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GO498_09860	ENOG4108JQ2	peptide transport system atp-binding protein
GO498_09865	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GO498_09870	ENOG4108K3A	Glutathione S-transferase
GO498_09875	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GO498_09880	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GO498_09885	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GO498_09890	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GO498_09895	ENOG4108XTF	Outer Membrane Lipoprotein
GO498_09905	ENOG4105XZD	Fe-S protein
GO498_09910	ENOG4108UYE	Lactoylglutathione lyase
GO498_09915	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GO498_09920	ENOG4105D7V	transposase
GO498_09925	ENOG4108RS6	transposase
GO498_09930	ENOG4105M2J	Glutaredoxin
GO498_09935	ENOG4105MPK	DNA polymerase III subunit theta
GO498_10150	ENOG4105HRS	Antitermination protein
GO498_10165	ENOG4105CDU	Replicative dna helicase
GO498_10245	ENOG4108PNI	recT protein
GO498_10255	ENOG4108UUM	single-stranded DNA-binding protein
GO498_10305	ENOG4108I1J	Integrase
GO498_10310	ENOG4105NAE	bifunctional deaminase-reductase domain protein
GO498_10325	ENOG4105HF0	Membrane
GO498_10330	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GO498_10340	ENOG4105ETE	Transcriptional regulator (LacI family
GO498_10345	ENOG4105F52	Transcriptional regulator
GO498_10350	ENOG4105CZQ	inner membrane transport protein YdhC
GO498_10355	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GO498_10360	ENOG4108R6K	riboflavin synthase, subunit alpha
GO498_10365	ENOG4107QI1	Mate efflux family protein
GO498_10380	ENOG4105CA9	Pyruvate kinase
GO498_10385	ENOG4105E5D	amino acid
GO498_10390	ENOG4105CVK	Glutamate decarboxylase
GO498_10400	ENOG4105KMX	major outer membrane lipoprotein
GO498_10405	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GO498_10410	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GO498_10415	ENOG4105C9B	Cysteine desulfurase
GO498_10420	ENOG4105JRK	feS assembly protein SufD
GO498_10425	ENOG4105C3K	feS assembly ATPase SufC
GO498_10430	ENOG4105DIW	FeS assembly protein SUFB
GO498_10435	ENOG4108Z4V	iron-sulfur cluster assembly
GO498_10445	ENOG4105KA0	thioesterase Superfamily protein
GO498_10450	ENOG4105CQB	FAD linked oxidase domain protein
GO498_10455	ENOG4105IPI	Membrane
GO498_10460	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GO498_10465	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GO498_10470	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GO498_10475	ENOG4107F3C	Hemin uptake protein
GO498_10480	ENOG4107ENK	receptor
GO498_10485	ENOG4107ENK	receptor
GO498_10490	ENOG4106QJH	hemin transport protein
GO498_10495	ENOG4107R4I	Periplasmic binding protein
GO498_10500	ENOG4105EHG	Permease protein
GO498_10505	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GO498_10510	ENOG4105EW9	transcriptional regulator AsnC family
GO498_10515	ENOG4105N14	lysine exporter protein LysE YggA
GO498_10520	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GO498_10525	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GO498_10530	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GO498_10545	ENOG4105KAF	membrAne
GO498_10550	ENOG4105D5M	phosphate starvation-inducible protein
GO498_10560	ENOG4105RWS	endonuclease I
GO498_10570	ENOG4107XM3	UPF0442 protein
GO498_10575	ENOG4105DWK	Membrane
GO498_10595	ENOG410657R	replicase EC 2.7
GO498_10600	ENOG4108U51	Universal stress protein
GO498_10610	ENOG4108U51	Universal stress protein
GO498_10615	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GO498_10620	ENOG4105XVG	cytoplasmic protein
GO498_10630	ENOG4105D52	delta-aminolevulinic acid dehydratase
GO498_10640	ENOG4105DZC	cytosine deaminase
GO498_10645	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
GO498_10650	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
GO498_10655	ENOG4105C26	Dehydrogenase
GO498_10660	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
GO498_10665	ENOG4105C94	Transporter
GO498_10670	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GO498_10680	ENOG4108M66	Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity)
GO498_10685	ENOG4105CW0	outer membrane usher protein
GO498_10690	ENOG4108AF8	Chaperone
GO498_10695	ENOG4108S54	Fimbrial protein
GO498_10700	ENOG4108WDE	Fimbrial protein
GO498_10705	ENOG4105ZUU	Transcriptional regulator
GO498_10710	ENOG4108JQ7	(ABC) transporter
GO498_10715	ENOG4105C3U	ABC transporter
GO498_10720	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GO498_10730	ENOG4107QSI	ABC, transporter
GO498_10735	ENOG4107QSI	ABC, transporter
GO498_10745	ENOG4105WZK	nitrite reductase NADPH small subunit
GO498_10750	ENOG4107QZF	nitrite reductase NADPH large subunit
GO498_10760	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GO498_10765	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GO498_10775	ENOG4108JQ7	(ABC) transporter
GO498_10780	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GO498_10785	ENOG4108EKI	Dehydrogenase
GO498_10790	ENOG4107104	thymidine kinase
GO498_10805	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GO498_10810	ENOG4105I93	response regulator
GO498_10815	ENOG4105K5B	UPF0225 protein
GO498_10820	ENOG4105CIY	formyltetrahydrofolate deformylase
GO498_10830	ENOG4105ETT	transcriptional Regulator, LysR family
GO498_10835	ENOG4105CGK	Exodeoxyribonuclease III
GO498_10840	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GO498_10845	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
GO498_10850	ENOG41069NU	Nitroreductase
GO498_10855	ENOG4105D07	Signal peptide peptidase, SppA
GO498_10860	ENOG4105HDK	L-asparaginase
GO498_10865	ENOG4108RWI	nicotinamidase
GO498_10870	ENOG4105VUT	cytoplasmic protein
GO498_10875	ENOG4105E0X	reductase
GO498_10885	ENOG4105DSB	aldose 1-epimerase
GO498_10890	ENOG4105GNX	MltA-interacting MipA family protein
GO498_10895	ENOG4105C8H	hydrogenase maturation protein Hypf
GO498_10900	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GO498_10905	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GO498_10910	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
GO498_10915	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GO498_10920	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GO498_10930	ENOG410814C	multidrug resistance protein
GO498_10935	ENOG4105F27	Major Facilitator
GO498_10950	ENOG4105D7X	high-affinity nickel-transporter
GO498_10955	ENOG41065CD	Exported protein
GO498_10985	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GO498_10990	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GO498_10995	ENOG4105WH1	Two component transcriptional regulator luxr family
GO498_11000	ENOG4108TVJ	Nitroreductase
GO498_11005	ENOG4105CBT	Fructose-1,6-bisphosphatase
GO498_11010	ENOG41080QX	K07048 phosphotriesterase-related protein
GO498_11025	ENOG4108RVA	ribokinase
GO498_11045	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
GO498_11070	ENOG4108VEN	abc transporter atp-binding protein
GO498_11080	ENOG4107XNE	ABC transporter, periplasmic molybdate-binding protein
GO498_11085	ENOG4105DKT	Transcriptional regulator
GO498_11090	ENOG4105VF7	tolerance protein
GO498_11105	ENOG410756H	nucleotidyltransferase
GO498_11150	ENOG4105DFP	Integrase
GO498_11155	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GO498_11160	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GO498_11165	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GO498_11175	ENOG4105CUG	Oligopeptidase b
GO498_11190	ENOG4105C6K	Malic enzyme
GO498_11195	ENOG4105WH1	Two component transcriptional regulator luxr family
GO498_11205	ENOG4105KUZ	arsenate reductase
GO498_11210	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GO498_11225	ENOG4105D7V	transposase
GO498_11230	ENOG4105WD1	Membrane
GO498_11235	ENOG4105XYK	UPF0370 protein
GO498_11240	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GO498_11245	ENOG4108VMM	UPF0756 membrane protein
GO498_11250	ENOG4105CGZ	zinc metallopeptidase
GO498_11255	ENOG4105C8V	SAICAR synthetase
GO498_11260	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GO498_11265	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GO498_11270	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GO498_11275	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GO498_11280	ENOG4105C02	permease
GO498_11285	ENOG4105ERG	peptidase m48, ste24p
GO498_11290	ENOG4105K89	arsenate reductase
GO498_11295	ENOG4105EAA	nucleoside
GO498_11300	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
GO498_11305	ENOG4105CUY	Mechanosensitive ion channel
GO498_11310	ENOG4105C2W	permease
GO498_11315	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GO498_11320	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GO498_11325	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GO498_11330	ENOG4108MK9	spermidine N(1)-acetyltransferase
GO498_11335	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GO498_11340	ENOG4105C9X	ppx gppa phosphatase
GO498_11345	ENOG4105CJW	magnesium transporter
GO498_11370	ENOG4105DUX	Transporter
GO498_11375	ENOG4105D7V	transposase
GO498_11385	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GO498_11390	ENOG4105BZS	acriflavin resistance protein
GO498_11395	ENOG4105BZS	acriflavin resistance protein
GO498_11400	ENOG4105EB3	Histidine kinase
GO498_11405	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GO498_11410	ENOG4105CFP	Peptidase U32
GO498_11415	ENOG4107TE5	Lipid kinase
GO498_11420	ENOG4105EIE	fructose-bisphosphate aldolase
GO498_11425	ENOG4105DWF	phosphomethylpyrimidine kinase
GO498_11430	ENOG41079UR	PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity)
GO498_11435	ENOG4105C85	amino acid
GO498_11445	ENOG4108W3Q	Transcriptional regulator
GO498_11450	ENOG410667J	hydrolase
GO498_11455	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GO498_11460	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
GO498_11465	ENOG4105BZG	amino acid carrier protein
GO498_11470	ENOG4105MPK	DNA polymerase III subunit theta
GO498_11480	ENOG4105X5C	UPF0181 protein
GO498_11485	ENOG4105CRQ	synthase (Component I)
GO498_11490	ENOG4105P8F	nudix hydrolase
GO498_11495	ENOG4105EJQ	L-serine dehydratase
GO498_11500	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
GO498_11505	ENOG4105DHI	Methyltransferase
GO498_11510	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
GO498_11515	ENOG41081QV	Universal stress protein
GO498_11525	ENOG4108U51	Universal stress protein
GO498_11530	ENOG4105C85	amino acid
GO498_11540	ENOG4105CK7	Sodium proline symporter
GO498_11545	ENOG4105C26	Dehydrogenase
GO498_11550	ENOG4108M9K	flagella biosynthesis protein FliZ
GO498_11555	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GO498_11560	ENOG4105I03	Flagellin
GO498_11570	ENOG4105DTS	flagellar hook-associated
GO498_11575	ENOG4105MQ3	flagellar protein FliS
GO498_11580	ENOG4105YXP	it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity)
GO498_11605	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GO498_11610	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GO498_11615	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GO498_11620	ENOG41090PJ	Flagellar assembly protein
GO498_11625	ENOG4108JIR	Flagellum-specific ATP synthase
GO498_11630	ENOG4105GSA	Flagellar export protein flij
GO498_11635	ENOG4105WF4	Flagellar hook-length control protein
GO498_11640	ENOG4107ZI8	flagellar basal body-associated protein flil
GO498_11645	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GO498_11650	ENOG4105DD5	Flagellar motor switch protein
GO498_11655	ENOG4105K0P	flagellar biosynthesis protein
GO498_11660	ENOG4105CN7	Flagellar biosynthetic protein FliP
GO498_11665	ENOG4105VS8	Flagellar biosynthetic protein fliq
GO498_11670	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GO498_11675	ENOG4105DTJ	flagellar hook-associated protein
GO498_11680	ENOG4105E1Q	flagellar hook-associated protein
GO498_11685	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GO498_11690	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GO498_11695	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GO498_11700	ENOG4105CGA	flagellar basal-body rod protein FlgG
GO498_11705	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GO498_11710	ENOG4105BZE	flagellar hook protein, FlgE
GO498_11715	ENOG4105W00	Flagellar hook capping protein
GO498_11720	ENOG4108ZC9	flagellar basal-body rod protein flgc
GO498_11725	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GO498_11730	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
GO498_11735	ENOG4105M9M	anti-sigma28 factor FlgM
GO498_11740	ENOG4105QVD	Flagella synthesis protein FlgN
GO498_11745	ENOG4105CKT	filamentous hemagglutinin
GO498_11755	ENOG4105D7B	Flagellar biosynthesis protein flha
GO498_11760	ENOG4105D00	flagellar biosynthetic protein flhB
GO498_11770	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GO498_11775	ENOG4108VYJ	response regulator receiver protein
GO498_11780	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GO498_11785	ENOG4105BZU	Histidine kinase
GO498_11790	ENOG4105C8Q	Methyl-accepting chemotaxis
GO498_11795	ENOG4105C8Q	Methyl-accepting chemotaxis
GO498_11800	ENOG4108V3W	Chemotaxis protein, CheW
GO498_11805	ENOG4105CBS	Chea signal transduction histidine kinase
GO498_11810	ENOG4105ER2	Ompa motb domain protein
GO498_11815	ENOG4107RD7	Flagellar Motor Protein, MotA
GO498_11820	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
GO498_11825	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
GO498_11830	ENOG4105KT7	mgtC SapB transporter
GO498_11840	ENOG4105VEQ	Cold shock protein
GO498_11845	ENOG4105GSJ	Inner membrane protein ylaC
GO498_11870	ENOG4105EKE	dihydroorotase
GO498_11875	ENOG4105PVA	Biofilm formation regulatory protein BssS
GO498_11885	ENOG4105DB1	molybdopterin oxidoreductase
GO498_11890	ENOG4106WHD	Tetrathionate reductase
GO498_11895	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GO498_11900	ENOG4106AFQ	Histidine kinase
GO498_11905	ENOG4108ZXC	Two component transcriptional regulator, luxr family
GO498_11910	ENOG4105D1S	lipid A biosynthesis
GO498_11915	ENOG4105C6X	Major Facilitator
GO498_11920	ENOG4105DUX	Transporter
GO498_11925	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GO498_11945	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GO498_11970	ENOG4108UMN	azlc family
GO498_11975	ENOG4105WBV	Transcriptional regulator
GO498_11980	ENOG4105F0I	Aminotransferase
GO498_11985	ENOG4108YK4	Acid-resistance membrane protein
GO498_11990	ENOG4105CUY	Mechanosensitive ion channel
GO498_11995	ENOG4107QY8	reductase
GO498_12000	ENOG4105QAX	Iron-sulfur
GO498_12005	ENOG4107KGK	dmso reductase anchor subunit
GO498_12125	ENOG4105MPK	DNA polymerase III subunit theta
GO498_12300	ENOG4108R1E	Serine threonine protein phosphatase 1
GO498_12450	ENOG4108UUM	single-stranded DNA-binding protein
GO498_12500	ENOG4108KU3	Integrase
GO498_12510	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
GO498_12515	ENOG41068CG	regulatoR
GO498_12520	ENOG4105BZU	Histidine kinase
GO498_12525	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GO498_12530	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GO498_12535	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GO498_12540	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GO498_12545	ENOG4105XPH	Ferredoxin
GO498_12550	ENOG4105M5B	(LipO)protein
GO498_12555	ENOG4105E0U	tyrosine-specific transport protein
GO498_12560	ENOG4108UII	YfaZ family
GO498_12565	ENOG4105CH6	catalase
GO498_12570	ENOG4105CEY	Amp-dependent synthetase and ligase
GO498_12575	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
GO498_12580	ENOG4108IPT	Naphthoate synthase
GO498_12585	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GO498_12590	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GO498_12595	ENOG4105E4F	Isochorismate synthase
GO498_12610	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GO498_12615	ENOG4105C8S	subunit m
GO498_12620	ENOG4105D65	subunit l
GO498_12625	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GO498_12630	ENOG4107UFS	subunit j
GO498_12635	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GO498_12640	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GO498_12645	ENOG4107R0R	NADH dehydrogenase subunit g
GO498_12650	ENOG4107QIZ	NADH dehydrogenase
GO498_12655	ENOG4105GKE	subunit e
GO498_12660	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GO498_12665	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GO498_12670	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GO498_12680	ENOG4107NQ8	LysR family Transcriptional regulator
GO498_12685	ENOG4105CHM	Aminotransferase
GO498_12690	ENOG4105DK2	UPF0207 protein
GO498_12695	ENOG4107QWE	)-transporter
GO498_12700	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
GO498_12705	ENOG4105XWI	UPF0304 protein
GO498_12710	ENOG4105PQ6	UPF0208 membrane protein
GO498_12715	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GO498_12720	ENOG4105C6K	Malic enzyme
GO498_12740	ENOG4105DZG	Dehydrogenase
GO498_12745	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GO498_12750	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
GO498_12760	ENOG4106ETB	IIa component
GO498_12770	ENOG4105PTV	Nudix Hydrolase
GO498_12775	ENOG4105CYM	Glutathione S-transferase
GO498_12780	ENOG4105ECP	epimerase
GO498_12785	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GO498_12790	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GO498_12795	ENOG4105E96	Colicin v production protein
GO498_12800	ENOG4108S3P	Sporulation domain protein
GO498_12805	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GO498_12810	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GO498_12815	ENOG4105DQR	SNARE associated Golgi
GO498_12820	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GO498_12825	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GO498_12830	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GO498_12835	ENOG4108NKV	transcriptional regulator
GO498_12840	ENOG410631K	Membrane
GO498_12845	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GO498_12850	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GO498_12855	ENOG4105XYF	acetyltransferase
GO498_12865	ENOG4105MH2	YfcL protein
GO498_12870	ENOG4108BPE	-transporting atpase
GO498_12875	ENOG4105EJ9	Membrane
GO498_12880	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GO498_12885	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GO498_12895	ENOG4108DG9	Smr protein MutS2
GO498_12900	ENOG4108BY2	phosphohistidine phosphatase
GO498_12905	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GO498_12910	ENOG4105CHU	acetyl-coa acetyltransferase
GO498_12915	ENOG4105KZW	UPF0381 protein
GO498_12920	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GO498_12925	ENOG410903C	(LipO)protein
GO498_12945	ENOG4108J2R	molybdopterin oxidoreductase
GO498_12950	ENOG4105QAX	Iron-sulfur
GO498_12955	ENOG4108NWD	Cytochrome
GO498_12960	ENOG4105ZUU	Transcriptional regulator
GO498_13005	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GO498_13020	ENOG4105CHR	reductase
GO498_13030	ENOG4105VRT	cytoplasmic protein
GO498_13035	ENOG4105D9N	nucleoside
GO498_13040	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GO498_13050	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GO498_13055	ENOG4105EXN	Sulfate transport protein CysZ
GO498_13060	ENOG4105C6T	cysteine synthase
GO498_13065	ENOG4105KZ7	phosphocarrier protein hpr
GO498_13075	ENOG4105C5Y	PTS System
GO498_13080	ENOG4105C6T	cysteine synthase
GO498_13085	ENOG4108IJ6	ABC transporter
GO498_13090	ENOG4105ECW	sulfate abc transporter
GO498_13095	ENOG4108I5D	sulfate abc transporter
GO498_13100	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
GO498_13105	ENOG4105EZR	dyp-type peroxidase family protein
GO498_13110	ENOG4105E7K	(LipO)protein
GO498_13115	ENOG4108R6G	acetyltransferase
GO498_13120	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GO498_13130	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GO498_13135	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GO498_13140	ENOG4105N21	Membrane
GO498_13145	ENOG4105CUT	histidyl-tRNA synthetase
GO498_13150	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GO498_13155	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
GO498_13165	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GO498_13170	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GO498_13175	ENOG4108JQB	penicillin-binding protein 1C
GO498_13180	ENOG4105DN3	alpha-2-macroglobulin domain protein
GO498_13185	ENOG4105YYA	enhanced serine sensitivity protein SseB
GO498_13190	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GO498_13195	ENOG4105WVQ	Fe-S assembly protein IscX
GO498_13200	ENOG4108ZIT	Ferredoxin, 2FE-2S
GO498_13205	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GO498_13210	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GO498_13215	ENOG4108Z4V	iron-sulfur cluster assembly
GO498_13220	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GO498_13225	ENOG4105C3J	Cysteine desulfurase
GO498_13230	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GO498_13235	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GO498_13255	ENOG4105D8G	Major Facilitator superfamily
GO498_13260	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GO498_13265	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GO498_13275	ENOG4108YZA	Nitrogen regulatory protein pii
GO498_13280	ENOG4105C4K	Nad synthetase
GO498_13285	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GO498_13290	ENOG4108SKK	alpha helix protein
GO498_13295	ENOG4107WP9	Histidine kinase
GO498_13300	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GO498_13305	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GO498_13310	ENOG4108TH4	Major fimbrial subunit
GO498_13315	ENOG4106PG1	outer membrane usher protein
GO498_13320	ENOG4108FZ9	Chaperone
GO498_13325	ENOG4108MDY	Fimbrial
GO498_13330	ENOG4108YUF	Fimbrial
GO498_13335	ENOG4108Z6B	deaminase
GO498_13340	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GO498_13345	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GO498_13350	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GO498_13355	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GO498_13360	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GO498_13365	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GO498_13370	ENOG4105C3F	Signal peptidase i
GO498_13375	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GO498_13380	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
GO498_13385	ENOG4105VQK	sigma E regulatory protein, MucB RseB
GO498_13390	ENOG41069PW	sigma-e factor negative regulatory protein
GO498_13395	ENOG4105EMN	RNA polymerase sigma factor
GO498_13400	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GO498_13405	ENOG4105C1J	atp-dependent rna helicase
GO498_13410	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GO498_13420	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GO498_13425	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GO498_13430	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GO498_13435	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GO498_13440	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GO498_13445	ENOG4105VDB	UPF0125 protein
GO498_13450	ENOG4108Z1B	Cyclase dehydrase
GO498_13455	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GO498_13500	ENOG4107NPW	Protein of unknown function (DUF1524)
GO498_13505	ENOG4105DZR	Type I site-specific deoxyribonuclease
GO498_13525	ENOG4105T38	integral membrane protein
GO498_13530	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GO498_13565	ENOG4105D5K	Hemolysin activator protein
GO498_13590	ENOG4105DWT	malate dehydrogenase (quinone)
GO498_13605	ENOG4105NF4	modulator of drug activity
GO498_13610	ENOG4105F27	Major Facilitator
GO498_13620	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GO498_13625	ENOG4107QR9	Iron-sulfur cluster binding protein
GO498_13630	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
GO498_13645	ENOG4105PI0	Ferredoxin
GO498_13650	ENOG4108XC3	NADH ubiquinone oxidoreductase
GO498_13660	ENOG4105NIV	Esterase
GO498_13665	ENOG4105D05	Receptor
GO498_13675	ENOG41060NJ	transcriptional regulator
GO498_13680	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GO498_13685	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GO498_13690	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GO498_13695	ENOG4105CMR	udp-glucose 4-epimerase
GO498_13710	ENOG4108RW8	Universal stress protein F
GO498_13715	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
GO498_13720	ENOG4105Z2P	Protein of unknown function (DUF465)
GO498_13725	ENOG4105VVZ	metal-binding protein
GO498_13735	ENOG4105VXR	cytoplasmic protein
GO498_13740	ENOG4108YYQ	gCN5-related N-acetyltransferase
GO498_13795	ENOG4105CW0	outer membrane usher protein
GO498_13800	ENOG4108VEV	chaperone
GO498_13805	ENOG4105X0I	Fimbrial
GO498_13830	ENOG4108T1M	outer membrane protein x
GO498_13845	ENOG4105CRK	lysyL-tRNA synthetase
GO498_13855	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GO498_13860	ENOG4105T95	Thiol disulfide interChange protein
GO498_13865	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GO498_13870	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GO498_13885	ENOG4105Y75	tpr repeat protein
GO498_13890	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GO498_13900	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GO498_13905	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GO498_13910	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GO498_13915	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GO498_13920	ENOG4105D0A	hydroxylase
GO498_13925	ENOG4107RAQ	aminopeptidase
GO498_13930	ENOG4105E07	UPF0149 protein
GO498_13935	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GO498_13945	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GO498_13955	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
GO498_13960	ENOG4108JJA	ABC, transporter
GO498_13965	ENOG4108JQ1	Dehydrogenase
GO498_13970	ENOG4105E66	phosphoriboisomerase A
GO498_13975	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GO498_13990	ENOG4105MPN	Membrane
GO498_13995	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GO498_14000	ENOG4105D64	Mechanosensitive ion channel
GO498_14005	ENOG4108ZIG	UPF0231 protein
GO498_14010	ENOG4107QIJ	Aconitate hydratase 2
GO498_14025	ENOG4107QN2	dihydrolipoyl dehydrogenase
GO498_14030	ENOG4107QSN	dihydrolipoamide acetyltransferase
GO498_14035	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GO498_14040	ENOG41073TP	transcriptional regulator
GO498_14045	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
GO498_14050	ENOG4108ZUW	Major pilin subunit
GO498_14055	ENOG4107QHF	type ii secretion system protein e
GO498_14065	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GO498_14070	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GO498_14075	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GO498_14085	ENOG4108I4D	hemolysin
GO498_14090	ENOG4106IWJ	hemolysin
GO498_14105	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GO498_14110	ENOG4108SR7	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
GO498_14120	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GO498_14125	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GO498_14130	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GO498_14135	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GO498_14145	ENOG4105DFU	Cell wall formation (By similarity)
GO498_14150	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GO498_14155	ENOG4105CNI	cell division protein FtsW
GO498_14165	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GO498_14170	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GO498_14175	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GO498_14180	ENOG4105CJN	penicillin-binding protein
GO498_14185	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GO498_14190	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GO498_14195	ENOG4108V6E	Cell division protein mraZ
GO498_14200	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GO498_14205	ENOG4108IQE	Amp-dependent synthetase and ligase
GO498_14210	ENOG41064T2	transcriptional regulator, lysR family
GO498_14220	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GO498_14225	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GO498_14230	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GO498_14235	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GO498_14240	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
GO498_14245	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
GO498_14255	ENOG4105VUH	addiction module killer protein
GO498_14260	ENOG4105CHR	reductase
GO498_14265	ENOG4105CYW	agmatinase
GO498_14270	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GO498_14275	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GO498_14280	ENOG4105D1V	cellulose synthase operon protein YhjU
GO498_14290	ENOG4105UTS	cellulose synthase operon protein YhjQ
GO498_14295	ENOG4107QZ7	Cellulose synthase catalytic subunit
GO498_14300	ENOG4107EEX	Cellulose synthase regulator protein
GO498_14320	ENOG41080HT	Transcriptional regulator, arsr family
GO498_14325	ENOG4105GPY	SprT protein
GO498_14330	ENOG4105CJW	magnesium transporter
GO498_14340	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GO498_14345	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
GO498_14350	ENOG4105C26	Dehydrogenase
GO498_14355	ENOG4105BZG	amino acid carrier protein
GO498_14370	ENOG4107SVH	Potassium channel protein
GO498_14375	ENOG4107QHE	Choloylglycine hydrolase
GO498_14380	ENOG4108YYC	ycei family
GO498_14385	ENOG4105DS1	cytochrome b561
GO498_14410	ENOG4105CBG	Sulfatase
GO498_14440	ENOG4105CHR	reductase
GO498_14450	ENOG4105CE4	GlcNAc 6-P deacetylase
GO498_14455	ENOG4108EQA	pts system
GO498_14460	ENOG4105F3R	pts system mannose fructose sorbose family iid
GO498_14465	ENOG4105ETZ	PTS System
GO498_14470	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
GO498_14475	ENOG4105E70	isomerase
GO498_14480	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
GO498_14485	ENOG4105E98	transcriptional regulator DeoR family
GO498_14490	ENOG4105C4X	radical SAM domain protein
GO498_14495	ENOG4105ENH	Sulfatase
GO498_14505	ENOG4105D2N	Aldolase
GO498_14510	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GO498_14515	ENOG4108UHU	Aldolase
GO498_14525	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GO498_14530	ENOG4107ZY0	Phenazine biosynthesis-like protein
GO498_14540	ENOG4105KBH	arsR family transcriptional regulator
GO498_14550	ENOG4105RHY	Pfam:UPF0157
GO498_14560	ENOG4105MPK	DNA polymerase III subunit theta
GO498_14785	ENOG4108V2F	protein ybcN in lambdoid DLP12 prophage regi
GO498_14815	ENOG4105CDU	Replicative dna helicase
GO498_14895	ENOG4108PNI	recT protein
GO498_14955	ENOG4108KU3	Integrase
GO498_14965	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GO498_14970	ENOG4105WQ3	Rna-binding protein
GO498_14975	ENOG4105DE4	1-phosphofructokinase
GO498_14980	ENOG4105C8N	cysteinyl-tRNA synthetase
GO498_14985	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GO498_14990	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GO498_14995	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GO498_15000	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GO498_15010	ENOG4105D64	Mechanosensitive ion channel
GO498_15015	ENOG4105CV6	ABC transporter, permease
GO498_15020	ENOG4108I0Y	(ABC) transporter
GO498_15025	ENOG4108UJV	acyl-CoA thioesterase i
GO498_15030	ENOG4105E1F	short-chain dehydrogenase reductase
GO498_15035	ENOG4107QR8	Thioredoxin
GO498_15040	ENOG4107QX8	SPFH domain, Band 7 family protein
GO498_15050	ENOG4108Z6Z	Transcriptional regulator
GO498_15055	ENOG4105C59	p-type ATPase
GO498_15065	ENOG4105MBR	gumn family
GO498_15070	ENOG4108Z66	YbaK ebsC protein
GO498_15075	ENOG4105CGH	5'-nucleotidase
GO498_15080	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GO498_15085	ENOG4107RE1	Inosine-guanosine kinase
GO498_15090	ENOG4108QY5	Ferric enterobactin transport protein
GO498_15095	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GO498_15100	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GO498_15105	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GO498_15110	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GO498_15115	ENOG4105FR1	rard protein
GO498_15120	ENOG4105D7K	pfkb domain protein
GO498_15125	ENOG4108HKT	sucrose-6-phosphate hydrolase
GO498_15130	ENOG4106NDP	Transcriptional regulator
GO498_15135	ENOG4108ZXC	Two component transcriptional regulator, luxr family
GO498_15150	ENOG4108HPI	phosphatidate Cytidylyltransferase
GO498_15160	ENOG4107653	Transcriptional regulator
GO498_15170	ENOG4105C5B	carbamate kinase
GO498_15175	ENOG4105G5A	Protein of unknown function (DUF2877)
GO498_15180	ENOG4107REC	cytoplasmic protein
GO498_15185	ENOG4107R1Q	Membrane protein FdrA
GO498_15190	ENOG4105CHJ	isochorismatase hydrolase
GO498_15195	ENOG4105EUB	pirin domain protein
GO498_15205	ENOG4107QPK	)-transporter
GO498_15230	ENOG4108T65	Fimbrial
GO498_15235	ENOG4105CW0	outer membrane usher protein
GO498_15245	ENOG4106EAR	Fimbrial protein
GO498_15265	ENOG4106CXJ	Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 sp P42190 PAPK_ECOLI PROTEIN PAPK PRECURSOR
GO498_15275	ENOG4106P2F	Pfam:Pili_assembly_C
GO498_15280	ENOG4106PG1	outer membrane usher protein
GO498_15290	ENOG4105HMV	Fimbrial protein
GO498_15295	ENOG4105ZUU	Transcriptional regulator
GO498_15300	ENOG4105DB7	PHP domain protein
GO498_15305	ENOG4105C5Y	PTS System
GO498_15310	ENOG4105CID	antiterminator
GO498_15315	ENOG4105K5X	acetyltransferase
GO498_15320	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GO498_15330	ENOG4108K5P	(LipO)protein
GO498_15335	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GO498_15340	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GO498_15345	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GO498_15350	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GO498_15355	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GO498_15360	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GO498_15370	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GO498_15375	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GO498_15380	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GO498_15385	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GO498_15390	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GO498_15395	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GO498_15400	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
GO498_15405	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GO498_15410	ENOG4105C85	amino acid
GO498_15460	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GO498_15465	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GO498_15470	ENOG4108UMI	ABC transporter, permease
GO498_15475	ENOG4105D01	(LipO)protein
GO498_15485	ENOG4108R96	Methyltransferase, YaeB family
GO498_15490	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GO498_15495	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
GO498_15500	ENOG4105M1T	rho-binding antiterminator
GO498_15505	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GO498_15510	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
GO498_15515	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GO498_15520	ENOG4105C0B	DNA polymerase III (alpha subunit)
GO498_15525	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GO498_15530	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GO498_15535	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GO498_15540	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GO498_15545	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GO498_15550	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GO498_15555	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO498_15565	ENOG4105KNE	Phosphatidate cytidylyltransferase
GO498_15570	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GO498_15575	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GO498_15580	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GO498_15585	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GO498_15590	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GO498_15595	ENOG4105CE9	30S ribosomal protein S2
GO498_15600	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GO498_15605	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GO498_15610	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GO498_15615	ENOG4108T8E	UPF0325 protein
GO498_15620	ENOG4105QDK	Flavodoxin
GO498_15630	ENOG4105CI1	PTS System
GO498_15635	ENOG4105DR9	pseudouridine synthase
GO498_15640	ENOG4105WP7	tRNA pseudouridine synthase C
GO498_15645	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GO498_15650	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GO498_15655	ENOG4105EWT	decarboxylase family
GO498_15660	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
GO498_15665	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
GO498_15670	ENOG4105M08	Membrane
GO498_15675	ENOG4105ETT	transcriptional Regulator, LysR family
GO498_15680	ENOG4105C9B	Cysteine desulfurase
GO498_15685	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GO498_15690	ENOG4105CUZ	uba thif-type nad fad binding protein
GO498_15695	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GO498_15715	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GO498_15720	ENOG4107QZM	n-acetylglutamate synthase
GO498_15725	ENOG4107QYX	exodeoxyribonuclease v alpha
GO498_15730	ENOG4107QKA	exodeoxyribonuclease V beta
GO498_15735	ENOG4107QXK	peptidase
GO498_15740	ENOG4105DSY	exodeoxyribonuclease V, gamma
GO498_15775	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GO498_15780	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GO498_15785	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GO498_15790	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GO498_15795	ENOG4105DP9	ABC transporter
GO498_15800	ENOG4106SMU	thiamine transporter membrane protein
GO498_15805	ENOG4107T0D	ABC, transporter
GO498_15810	ENOG4105VT3	DNA binding domain protein, excisionase family
GO498_15820	ENOG4105CQ2	DNA polymerase
GO498_15825	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
GO498_15830	ENOG4105D3G	Pseudouridine synthase
GO498_15835	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GO498_15840	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GO498_15845	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GO498_15850	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GO498_15855	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GO498_15860	ENOG4105NWN	ApaG protein
GO498_15865	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GO498_15870	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
GO498_15885	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
GO498_15890	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GO498_15895	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GO498_15900	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GO498_15905	ENOG4105IPS	esterase
GO498_15910	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GO498_15915	ENOG41087AY	ADP-Ribose pyrophosphatase
GO498_15920	ENOG4105DFG	type I secretion outer membrane protein
GO498_15925	ENOG4105F1G	UPF0441 protein
GO498_15930	ENOG4106032	Glutathionylspermidine synthase
GO498_15935	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
GO498_15940	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GO498_15945	ENOG4105W0Z	cytoplasmic protein
GO498_15950	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GO498_15955	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GO498_15960	ENOG4105I7R	Adenylate cyclase
GO498_15965	ENOG4106MWK	domain protein
GO498_15970	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GO498_15975	ENOG4107ZVW	dihydroneopterin aldolase
GO498_15980	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GO498_16000	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
GO498_16005	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GO498_16010	ENOG4105VCC	30S ribosomal protein S21
GO498_16015	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GO498_16020	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GO498_16035	ENOG4105FFC	UPF0187 protein
GO498_16045	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GO498_16050	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GO498_16055	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
GO498_16060	ENOG4105DUM	transcriptional regulator, lysR family
GO498_16065	ENOG4105C8Q	Methyl-accepting chemotaxis
GO498_16070	ENOG4105C8Q	Methyl-accepting chemotaxis
GO498_16075	ENOG41083B3	HAD-superfamily subfamily IB hydrolase
GO498_16120	ENOG4105DAX	Pfam:DUF2983
GO498_16175	ENOG4105CMT	Dihydroxyacetone kinase
GO498_16180	ENOG4108UTZ	Dihydroxyacetone kinase
GO498_16185	ENOG4105VDH	Dihydroxyacetone kinase
GO498_16190	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
GO498_16205	ENOG4105CXY	transporter
GO498_16210	ENOG4105CA9	Pyruvate kinase
GO498_16215	ENOG4105KSC	Transcriptional regulator, TraR DksA family
GO498_16225	ENOG4105D4T	Citrate transporter
GO498_16230	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GO498_16235	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GO498_16240	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GO498_16245	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GO498_16250	ENOG4105D9N	nucleoside
GO498_16255	ENOG4105EYA	deoxyribonuclease
GO498_16260	ENOG4108NRW	Phospholipase, patatin family
GO498_16270	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GO498_16285	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GO498_16295	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GO498_16310	ENOG4105EAM	Na Pi-cotransporter
GO498_16320	ENOG4105E93	esterase
GO498_16330	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
GO498_16335	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GO498_16340	ENOG4105EAC	phosphoserine phosphatase
GO498_16345	ENOG41062Z9	Membrane
GO498_16350	ENOG4105G0K	glycine radical enzyme YjjI family
GO498_16355	ENOG41076CZ	activating enzyme
GO498_16375	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GO498_16390	ENOG4105K64	Glycosyl transferase, family 2
GO498_16395	ENOG4108MG9	hydrogenase 3 maturation protease
GO498_16400	ENOG4105I6X	formate hydrogenlyase maturation
GO498_16405	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
GO498_16415	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GO498_16420	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GO498_16425	ENOG4107WQX	hydrogenase 4 membrane subunit
GO498_16430	ENOG4105D65	subunit l
GO498_16435	ENOG4107TDF	Formate hydrogenlyase subunit 4
GO498_16440	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GO498_16445	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
GO498_16450	ENOG4108YZG	isomerase
GO498_16455	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GO498_16460	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GO498_16470	ENOG4105CW0	outer membrane usher protein
GO498_16510	ENOG4108ZVF	(LipO)protein
GO498_16515	ENOG4105D7V	transposase
GO498_16520	ENOG4108RS6	transposase
GO498_16525	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GO498_16530	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GO498_16545	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GO498_16550	ENOG4108SIC	Transcriptional regulator
GO498_16790	ENOG4105EYM	Major Facilitator superfamily
GO498_16800	ENOG4105C0W	non-ribosomal peptide synthetase
GO498_16820	ENOG4105BZ1	(ABC) transporter
GO498_16875	ENOG4105UGU	tonB-dependent Receptor
GO498_16890	ENOG4108KBJ	Inner membrane protein YkgB
GO498_16915	ENOG4105CXN	decarboxylase
GO498_16950	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GO498_16995	ENOG4105CDU	Replicative dna helicase
GO498_17020	ENOG4105HA9	of methanol dehydrogenase type
GO498_17025	ENOG4108V0P	LemA family
GO498_17040	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GO498_17045	ENOG4105C54	Major Facilitator superfamily
GO498_17050	ENOG4105WQV	ferredoxin-like protein
GO498_17055	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GO498_17075	ENOG4105C1G	acyl-Coa dehydrogenase
GO498_17080	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
GO498_17085	ENOG4105CEY	Amp-dependent synthetase and ligase
GO498_17090	ENOG4106YT9	Enoyl-CoA hydratase
GO498_17100	ENOG4108XNW	Transcriptional activatory protein CaiF
GO498_17105	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GO498_17110	ENOG4108M1A	Chitin-binding protein
GO498_17115	ENOG4105Y3E	Modulates RecA activity (By similarity)
GO498_17135	ENOG4108UR8	BAX protein
GO498_17140	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GO498_17160	ENOG4105C6Z	Gluconate
GO498_17165	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GO498_17170	ENOG4105DIQ	Transcriptional regulator
GO498_17175	ENOG4105S10	periplasmic binding protein
GO498_17180	ENOG4105EHG	Permease protein
GO498_17185	ENOG4105E0A	ABC, transporter
GO498_17190	ENOG4108BSC	Methyltransferase
GO498_17195	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GO498_17225	ENOG4108M6W	surface presentation of antigens protein SpaS
GO498_17230	ENOG4108TN6	type iii secretion
GO498_17240	ENOG41075IY	surface presentation of antigens protein SpaP
GO498_17260	ENOG4108JIR	Flagellum-specific ATP synthase
GO498_17270	ENOG4108HR8	type iii secretion
GO498_17275	ENOG4108N8R	Invasion protein
GO498_17280	ENOG4105K44	type iii secretion
GO498_17285	ENOG41090HZ	type iii secretion
GO498_17295	ENOG4105Y7Q	type iii secretion
GO498_17305	ENOG4108RBT	type iii secretion
GO498_17325	ENOG4108Z4X	TRANSCRIPTIONal
GO498_17340	ENOG4105BZS	acriflavin resistance protein
GO498_17365	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
GO498_17370	ENOG4105KNY	Microcompartments protein
GO498_17375	ENOG4105F1A	Pyruvate formate-lyase
GO498_17380	ENOG4105C6N	Formate acetyltransferase
GO498_17395	ENOG4108EKI	Dehydrogenase
GO498_17400	ENOG4105KNY	Microcompartments protein
GO498_17405	ENOG4105KNY	Microcompartments protein
GO498_17410	ENOG4105KNY	Microcompartments protein
GO498_17440	ENOG4108WDE	Fimbrial protein
GO498_17445	ENOG4108AF8	Chaperone
GO498_17450	ENOG4105CW0	outer membrane usher protein
GO498_17455	ENOG4108SQA	Fimbrial
GO498_17470	ENOG4107RUE	extracellular solute-binding protein family 1
GO498_17475	ENOG4105D38	putrescine abc transporter
GO498_17480	ENOG4105F38	ABC transporter, permease
GO498_17500	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GO498_17505	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
GO498_17510	ENOG4105CDU	Replicative dna helicase
GO498_17515	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GO498_17520	ENOG4105CGF	Aromatic amino acid aminotransferase
GO498_17530	ENOG4105C44	Serine transporter
GO498_17535	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GO498_17540	ENOG4108UUM	single-stranded DNA-binding protein
GO498_17545	ENOG4105MYN	Zinc uptake regulation protein
GO498_17550	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GO498_17555	ENOG41080IJ	Diacylglycerol kinase
GO498_17560	ENOG4105E55	glycerol-3-phosphate acyltransferase
GO498_17565	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GO498_17570	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GO498_17575	ENOG4107QP8	phosphohexose isomerase
GO498_17580	ENOG4105CFH	Aspartokinase
GO498_17595	ENOG4105C3R	Methionine synthase
GO498_17600	ENOG41069M3	Transcriptional regulator
GO498_17605	ENOG4105C01	Dihydroxy-acid dehydratase
GO498_17610	ENOG4108UHU	Aldolase
GO498_17620	ENOG4108I9X	Isocitrate lyase
GO498_17625	ENOG4107QP3	malate synthase g
GO498_17630	ENOG4105CVG	Homoserine O-transsuccinylase
GO498_17670	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GO498_17675	ENOG4105C12	Phosphoribosylglycinamide synthetase
GO498_17680	ENOG4108T8B	Protein of unknown function (DUF1481)
GO498_17685	ENOG4105K70	DNA-binding protein
GO498_17690	ENOG4105R2J	Conserved Protein
GO498_17695	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
GO498_17700	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GO498_17705	ENOG4105E09	nadh pyrophosphatase
GO498_17715	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GO498_17720	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GO498_17725	ENOG4105D06	uba thif-type nad fad binding protein
GO498_17730	ENOG4105WHD	thiamine biosynthesis protein ThiS
GO498_17735	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GO498_17740	ENOG4105D41	biosynthesis protein thiH
GO498_17745	ENOG4105DNE	Transposase
GO498_17750	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GO498_17755	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GO498_17760	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GO498_17765	ENOG4108VZM	50s ribosomal protein L10
GO498_17770	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GO498_17775	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GO498_17780	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GO498_17785	ENOG4105PM1	preprotein translocase subunit SecE
GO498_17790	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GO498_17795	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GO498_17800	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GO498_17805	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GO498_17815	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GO498_17820	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
GO498_17825	ENOG4105WWK	YheO domain protein
GO498_17835	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GO498_17840	ENOG4105VRX	Protein slyX homolog
GO498_17845	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GO498_17850	ENOG4105VKU	nucleicacid-binding protein
GO498_17860	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GO498_17865	ENOG4105C5H	ABC transporter
GO498_17870	ENOG4105C8Q	Methyl-accepting chemotaxis
GO498_17875	ENOG4105C8Q	Methyl-accepting chemotaxis
GO498_17880	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GO498_17885	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
GO498_17895	ENOG4105DNZ	Alpha Beta Hydrolase
GO498_17900	ENOG4105YP7	UPF0270 protein
GO498_17905	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GO498_17910	ENOG4108UKZ	OsmC family
GO498_17915	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GO498_17920	ENOG4105C8Y	Acetylornithine aminotransferase
GO498_17930	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GO498_17940	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GO498_17945	ENOG4105C2M	dna polymerase I
GO498_17955	ENOG4108Z33	Thiol disulfide Interchange Protein
GO498_17960	ENOG4105E27	serine threonine protein kinase
GO498_17965	ENOG4105PC1	Conserved Protein
GO498_17970	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GO498_17975	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
GO498_17985	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GO498_17990	ENOG4105DC8	reductase
GO498_17995	ENOG4105D6S	protein involved in catabolism of external DNA
GO498_18005	ENOG4107H3J	ribonuclease
GO498_18010	ENOG4105VSH	4-oxalocrotonate tautomerase
GO498_18015	ENOG4105CS0	peptidase
GO498_18020	ENOG4105BZU	Histidine kinase
GO498_18025	ENOG4105CKT	filamentous hemagglutinin
GO498_18030	ENOG4108JQ7	(ABC) transporter
GO498_18035	ENOG4105C3U	ABC transporter
GO498_18040	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GO498_18045	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GO498_18050	ENOG4105DEF	Extracellular solute-binding protein, family 5
GO498_18055	ENOG4105D5K	Hemolysin activator protein
GO498_18070	ENOG4105R2A	(LipO)protein
GO498_18080	ENOG4105JKW	Valine--pyruvate aminotransferase
GO498_18085	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GO498_18090	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GO498_18095	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GO498_18120	ENOG4105D99	atp gtp-binding protein
GO498_18125	ENOG4105EN6	Membrane
GO498_18130	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GO498_18135	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GO498_18140	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GO498_18145	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GO498_18150	ENOG4105CB5	ATP-dependent DNA helicase recG
GO498_18155	ENOG4105D6U	Sodium Glutamate Symporter
GO498_18160	ENOG4105C2W	permease
GO498_18165	ENOG4105JV1	AsmA family
GO498_18175	ENOG4105FE9	pseudouridine synthase
GO498_18180	ENOG4105SUU	thioesterase domain
GO498_18185	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GO498_18190	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
GO498_18230	ENOG4105D4P	Coproporphyrinogen iii oxidase
GO498_18235	ENOG4107Y60	(LipO)protein
GO498_18245	ENOG4106B0W	Curli production assembly transport component CsgG
GO498_18250	ENOG4105BZM	domain protein
GO498_18255	ENOG4108RRZ	Transcription elongation factor GreB
GO498_18260	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GO498_18265	ENOG4105E0F	Histidine kinase
GO498_18270	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
GO498_18275	ENOG4105C8U	phosphate abc transporter
GO498_18280	ENOG4105E2Z	phosphate ABC transporter (Permease
GO498_18290	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GO498_18295	ENOG4105CT1	(ABC) transporter
GO498_18300	ENOG4105E5Q	amino acid AbC transporter
GO498_18305	ENOG4105DRP	amino acid AbC transporter
GO498_18330	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GO498_18345	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GO498_18350	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GO498_18355	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GO498_18360	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GO498_18370	ENOG41081XD	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GO498_18380	ENOG4105C7N	Xanthine uracil vitamin C permease
GO498_18405	ENOG4105XFK	Ferrous iron transport protein A
GO498_18410	ENOG4105CE1	Ferrous iron transport protein b
GO498_18415	ENOG41060N5	May function as a transcriptional regulator that controls feoABC expression (By similarity)
GO498_18425	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GO498_18430	ENOG4105MJ2	Competence protein
GO498_18435	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GO498_18440	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GO498_18445	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
GO498_18450	ENOG4105E98	transcriptional regulator DeoR family
GO498_18455	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GO498_18460	ENOG4105K78	MarR family Transcriptional regulator
GO498_18465	ENOG4105SYT	Methylenetetrahydrofolate reductase
GO498_18490	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
GO498_18500	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GO498_18510	ENOG4105EF1	ribulokinase
GO498_18520	ENOG4108S9F	abc transporter, atp-binding protein
GO498_18535	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GO498_18540	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
GO498_18545	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GO498_18555	ENOG4108T1M	outer membrane protein x
GO498_18560	ENOG410901P	UPF0249 protein
GO498_18565	ENOG4105F8D	glycoside hydrolase family 4
GO498_18570	ENOG4105EZV	Transcriptional regulator
GO498_18575	ENOG4105VCP	PTS System
GO498_18580	ENOG4105CK1	PTS System
GO498_18585	ENOG4105VZJ	PTS System
GO498_18595	ENOG4105DHS	permease protein
GO498_18600	ENOG4105CM4	permease protein
GO498_18605	ENOG4108IPW	abc transporter atp-binding protein
GO498_18615	ENOG4105DJB	Major Facilitator Superfamily
GO498_18620	ENOG4105CXK	mandelate racemase muconate lactonizing
GO498_18625	ENOG4105DRR	Transcriptional regulator, GntR family
GO498_18630	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
GO498_18635	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GO498_18640	ENOG4108UHU	Aldolase
GO498_18660	ENOG4105CXN	decarboxylase
GO498_18665	ENOG4105D5Q	Arginine ornithine antiporter
GO498_18675	ENOG4107QY8	reductase
GO498_18680	ENOG4105QAX	Iron-sulfur
GO498_18685	ENOG4107KGK	dmso reductase anchor subunit
GO498_18690	ENOG4105ETE	Transcriptional regulator (LacI family
GO498_18700	ENOG4105EAA	nucleoside
GO498_18705	ENOG4105KT7	mgtC SapB transporter
GO498_18725	ENOG4105QEK	Transcriptional regulator
GO498_18730	ENOG4108R66	Conserved Protein
GO498_18735	ENOG4107RJ1	sodium solute
GO498_18745	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
GO498_18750	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GO498_18755	ENOG4105C8J	)-transporter
GO498_18765	ENOG4105CI1	PTS System
GO498_18770	ENOG4108Q3X	Transcriptional regulator
GO498_18780	ENOG4105D3G	Pseudouridine synthase
GO498_18785	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
GO498_18790	ENOG4105N1F	Hnh endonuclease
GO498_18795	ENOG4108WC9	type VI secretion system effector, hcp1 family
GO498_18800	ENOG4105CS6	Rhs element vgr protein
GO498_18835	ENOG4106PYX	Receptor
GO498_18840	ENOG4108N3D	putative enzyme
GO498_18870	ENOG4105DGW	oligopeptidase A
GO498_18875	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
GO498_18880	ENOG4108R85	Short chain dehydrogenase
GO498_18885	ENOG4105D82	Glutamate dehydrogenase
GO498_18890	ENOG4108M6U	Universal stress protein A
GO498_18895	ENOG4108V6B	universal stress protein B
GO498_18900	ENOG4105CJ3	phosphate transporter
GO498_18905	ENOG4105CBX	hi0933 family
GO498_18910	ENOG4105C2I	pirin domain protein
GO498_18915	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GO498_18920	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GO498_18925	ENOG4105VEJ	Heat shock protein
GO498_18930	ENOG4105DQY	intracellular growth attenuator
GO498_18935	ENOG4107RK2	ADP-ribose diphosphatase NudE
GO498_18940	ENOG4105D01	(LipO)protein
GO498_18945	ENOG4108JQC	penicillin-binding protein 1A
GO498_18965	ENOG4105E4G	Type IV pilus
GO498_18970	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GO498_18975	ENOG4105D49	3-dehydroquinate synthase
GO498_18990	ENOG4105DJV	ribulose-phosphate 3-epimerase
GO498_18995	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GO498_19000	ENOG4105C31	Tryptophanyl-tRNA synthetase
GO498_19005	ENOG4105D7V	transposase
GO498_19010	ENOG4108RS6	transposase
GO498_19015	ENOG4108RPX	mosc domain containing protein
GO498_19020	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GO498_19025	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GO498_19030	ENOG41062QD	Membrane
GO498_19035	ENOG4107QN1	sodium solute
GO498_19040	ENOG4105DIJ	Phosphoethanolamine transferase
GO498_19045	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
GO498_19050	ENOG4107QR9	Iron-sulfur cluster binding protein
GO498_19055	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GO498_19080	ENOG4107EJG	GntR family transcriptional regulator
GO498_19090	ENOG4108RVA	ribokinase
GO498_19095	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
GO498_19100	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GO498_19105	ENOG4105CU9	asparagine synthetase A
GO498_19110	ENOG4108VVK	transcriptional Regulator, AsnC
GO498_19115	ENOG4105QTB	Flavodoxin
GO498_19120	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GO498_19125	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GO498_19130	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
GO498_19135	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GO498_19140	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GO498_19145	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GO498_19150	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GO498_19155	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GO498_19160	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GO498_19165	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GO498_19170	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GO498_19175	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GO498_19180	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GO498_19185	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GO498_19195	ENOG4105C4Y	ABC transporter
GO498_19200	ENOG41080HI	glycine oxidase
GO498_19215	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
GO498_19260	ENOG4105E6S	usher protein(
GO498_19285	ENOG4105H4F	exported protein
GO498_19295	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
GO498_19305	ENOG4107QZ7	Cellulose synthase catalytic subunit
GO498_19315	ENOG4105EJG	cellulose synthase
GO498_19325	ENOG4105BZU	Histidine kinase
GO498_19330	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GO498_19335	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
GO498_19340	ENOG4107T7U	Sulfatase
GO498_19345	ENOG4105EM7	Selenocysteine-specific translation elongation factor
GO498_19350	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
GO498_19355	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
GO498_19360	ENOG4108MG3	formate dehydrogenase
GO498_19365	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GO498_19375	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GO498_19395	ENOG4106P55	Transcriptional regulator
GO498_19415	ENOG41067XB	TonB family
GO498_19430	ENOG4108UQ5	membrane protein YcdZ
GO498_19435	ENOG4105CAF	HipA N-terminal domain protein
GO498_19505	ENOG4107QKA	exodeoxyribonuclease V beta
GO498_19590	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GO498_19595	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GO498_19600	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GO498_19605	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GO498_19610	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GO498_19615	ENOG4105VG0	50S ribosomal protein l34
GO498_19915	ENOG4105C3F	Signal peptidase i
GO498_20010	ENOG4105EUV	Phenol 2-monooxygenase
GO498_20030	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GO498_20125	ENOG4107W31	Pentapeptide repeat protein
GO498_20320	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
GO498_20325	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
GO498_20350	ENOG4105GMB	type VI secretion system effector, hcp1 family
GO498_20365	ENOG4108UUM	single-stranded DNA-binding protein
GO498_20375	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GO498_20380	ENOG4105KT5	UmuD protein
