locus-tag	class	description
Patl_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Patl_0004	COG0187	DNA topoisomerase II activity
Patl_0005	COG1794	racemase activity, acting on amino acids and derivatives
Patl_0006	COG5001	Diguanylate cyclase
Patl_0006	COG3300	MHYT domain
Patl_0008	COG0751	glycine-tRNA ligase activity
Patl_0009	COG0752	glycyl-tRNA synthetase alpha subunit
Patl_0010	COG2818	Glycosylase
Patl_0012	COG3078	GTPase activator activity
Patl_0014	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Patl_0015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Patl_0015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Patl_0016	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Patl_0020	COG0569	domain protein
Patl_0021	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Patl_0021	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Patl_0022	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Patl_0025	COG0758	DNA mediated transformation
Patl_0026	COG2922	Belongs to the Smg family
Patl_0027	COG0551	DNA topoisomerase type I activity
Patl_0028	COG0009	L-threonylcarbamoyladenylate synthase
Patl_0029	COG0408	coproporphyrinogen oxidase activity
Patl_0030	COG3047	cAMP biosynthetic process
Patl_0031	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Patl_0033	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Patl_0036	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Patl_0042	COG2234	aminopeptidase activity
Patl_0045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Patl_0046	COG2003	Belongs to the UPF0758 family
Patl_0048	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Patl_0049	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Patl_0051	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Patl_0053	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Patl_0055	COG3642	lipopolysaccharide core region biosynthetic process
Patl_0057	COG1519	Transferase
Patl_0062	COG1063	alcohol dehydrogenase
Patl_0063	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Patl_0066	COG3161	chorismate lyase activity
Patl_0067	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Patl_0070	COG0210	DNA helicase
Patl_0075	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Patl_0076	COG1194	a g-specific adenine glycosylase
Patl_0078	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Patl_0079	COG2813	Specifically methylates the guanine in position
Patl_0080	COG0297	glycogen (starch) synthase activity
Patl_0081	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Patl_0081	COG4191	Histidine kinase
Patl_0082	COG0745	RESPONSE REGULATOR receiver
Patl_0084	COG4232	protein-disulfide reductase activity
Patl_0086	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Patl_0087	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
Patl_0089	COG0511	ligase activity, forming carbon-carbon bonds
Patl_0090	COG0439	Biotin carboxylase
Patl_0092	COG2264	protein methyltransferase activity
Patl_0100	COG1846	Transcriptional regulator
Patl_0101	COG1764	response to oxidative stress
Patl_0102	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Patl_0105	COG1960	acyl-CoA dehydrogenase activity
Patl_0107	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Patl_0108	COG0545	Peptidyl-prolyl cis-trans isomerase
Patl_0110	COG2900	Belongs to the SlyX family
Patl_0112	COG0488	(ABC) transporter
Patl_0114	COG0583	DNA-binding transcription factor activity
Patl_0115	COG2855	membrane
Patl_0117	COG3537	Alpha-1,2-mannosidase
Patl_0120	COG3537	Alpha-1,2-mannosidase
Patl_0121	COG1609	Transcriptional regulator
Patl_0124	COG2971	BadF BadG BcrA BcrD
Patl_0125	COG1446	asparaginase
Patl_0129	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Patl_0130	COG3537	Alpha-1,2-mannosidase
Patl_0134	COG0429	hydrolase of the alpha beta-hydrolase fold
Patl_0135	COG3089	Belongs to the UPF0270 family
Patl_0137	COG1218	3'(2'),5'-bisphosphate nucleotidase
Patl_0138	COG0494	nUDIX hydrolase
Patl_0139	COG1011	Hydrolase
Patl_0140	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Patl_0146	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Patl_0147	COG2814	Major facilitator Superfamily
Patl_0148	COG0629	single-stranded DNA binding
Patl_0149	COG4771	TonB-dependent receptor
Patl_0151	COG0415	Belongs to the DNA photolyase family
Patl_0152	COG0415	Belongs to the DNA photolyase family
Patl_0153	COG1012	belongs to the aldehyde dehydrogenase family
Patl_0154	COG0318	PFAM AMP-dependent synthetase and ligase
Patl_0155	COG4771	TonB-dependent receptor
Patl_0158	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Patl_0160	COG3391	amine dehydrogenase activity
Patl_0161	COG1309	transcriptional regulator
Patl_0171	COG3267	Type II secretory pathway component ExeA
Patl_0171	COG3409	Peptidoglycan-binding domain 1 protein
Patl_0174	COG1459	type II secretion system
Patl_0177	COG4969	Belongs to the N-Me-Phe pilin family
Patl_0183	COG1077	Cell shape determining protein MreB Mrl
Patl_0184	COG1792	Involved in formation and maintenance of cell shape
Patl_0185	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Patl_0186	COG0424	maF-like protein
Patl_0187	COG1530	ribonuclease E activity
Patl_0188	COG3164	Protein of unknown function
Patl_0189	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Patl_0190	COG0312	modulator of DNA gyrase
Patl_0192	COG3028	Belongs to the UPF0307 family
Patl_0193	COG0312	modulator of DNA gyrase
Patl_0199	COG0006	proline dipeptidase activity
Patl_0201	COG1250	3-hydroxyacyl-CoA dehydrogenase
Patl_0201	COG1024	Enoyl-CoA hydratase
Patl_0202	COG0183	Belongs to the thiolase family
Patl_0203	COG4771	TonB-dependent receptor
Patl_0208	COG1309	transcriptional regulator
Patl_0209	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_0210	COG2326	polyphosphate kinase activity
Patl_0212	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Patl_0215	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Patl_0216	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
Patl_0217	COG5002	protein histidine kinase activity
Patl_0218	COG0745	RESPONSE REGULATOR receiver
Patl_0224	COG3954	Phosphoribulokinase
Patl_0225	COG0745	RESPONSE REGULATOR receiver
Patl_0227	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Patl_0230	COG3031	protein transport across the cell outer membrane
Patl_0232	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Patl_0233	COG1459	type II secretion system
Patl_0234	COG2165	general secretion pathway protein
Patl_0235	COG2165	general secretion pathway protein
Patl_0236	COG2165	general secretion pathway protein
Patl_0237	COG4795	General secretion pathway protein
Patl_0238	COG3156	type II secretion system protein K
Patl_0240	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Patl_0242	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Patl_0243	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Patl_0245	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Patl_0246	COG2816	NAD+ diphosphatase activity
Patl_0247	COG0735	belongs to the Fur family
Patl_0249	COG0432	Pfam Uncharacterised protein family UPF0047
Patl_0250	COG2885	chlorophyll binding
Patl_0251	COG0305	Participates in initiation and elongation during chromosome replication
Patl_0252	COG0514	ATP-dependent DNA helicase (RecQ)
Patl_0253	COG2050	protein possibly involved in aromatic compounds catabolism
Patl_0260	COG0729	surface antigen
Patl_0261	COG2911	Protein conserved in bacteria
Patl_0262	COG2239	Acts as a magnesium transporter
Patl_0263	COG5487	UPF0391 membrane protein
Patl_0265	COG0745	RESPONSE REGULATOR receiver
Patl_0265	COG3706	GGDEF domain
Patl_0266	COG0151	Belongs to the GarS family
Patl_0269	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
Patl_0272	COG3118	belongs to the thioredoxin family
Patl_0276	COG2272	Belongs to the type-B carboxylesterase lipase family
Patl_0286	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Patl_0291	COG4948	Mandelate Racemase Muconate Lactonizing
Patl_0292	COG1609	Transcriptional regulator
Patl_0293	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Patl_0295	COG4771	TonB-dependent receptor
Patl_0301	COG1469	GTP cyclohydrolase I activity
Patl_0306	COG1136	(ABC) transporter
Patl_0310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Patl_0315	COG1960	acyl-CoA dehydrogenase activity
Patl_0317	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Patl_0318	COG1024	Enoyl-CoA hydratase
Patl_0321	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_0322	COG0318	PFAM AMP-dependent synthetase and ligase
Patl_0340	COG2959	enzyme of heme biosynthesis
Patl_0342	COG0181	hydroxymethylbilane synthase activity
Patl_0346	COG1965	Belongs to the frataxin family
Patl_0347	COG0194	GDP metabolic process
Patl_0348	COG1758	RNA polymerase activity
Patl_0349	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Patl_0351	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Patl_0353	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Patl_0354	COG0742	ribosomal rna small subunit methyltransferase
Patl_0355	COG0346	lactoylglutathione lyase activity
Patl_0356	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Patl_0356	COG0678	peroxiredoxin activity
Patl_0358	COG4555	ABC transporter
Patl_0373	COG0501	Belongs to the peptidase M48B family
Patl_0375	COG2081	HI0933 family
Patl_0377	COG4771	TonB-dependent receptor
Patl_0379	COG1053	succinate dehydrogenase
Patl_0385	COG1607	acyl-coa hydrolase
Patl_0390	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Patl_0391	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Patl_0392	COG4135	transport system, permease component
Patl_0393	COG4134	Bacterial extracellular solute-binding protein
Patl_0395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Patl_0398	COG5001	Diguanylate cyclase
Patl_0398	COG2203	Gaf domain
Patl_0398	COG4251	negative regulation of phosphorylation
Patl_0398	COG3706	GGDEF domain
Patl_0400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Patl_0402	COG4249	Peptidase C14 caspase catalytic subunit p20
Patl_0402	COG2319	Wd-40 repeat
Patl_0404	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Patl_0405	COG2234	aminopeptidase activity
Patl_0410	COG3483	tryptophan 2,3-dioxygenase activity
Patl_0414	COG4771	TonB-dependent receptor
Patl_0417	COG1648	precorrin-2 dehydrogenase activity
Patl_0417	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Patl_0418	COG0513	Belongs to the DEAD box helicase family
Patl_0423	COG4251	negative regulation of phosphorylation
Patl_0424	COG0784	Response regulator, receiver
Patl_0425	COG1454	alcohol dehydrogenase
Patl_0426	COG0824	Thioesterase
Patl_0428	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Patl_0429	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Patl_0430	COG1538	Outer membrane efflux protein
Patl_0431	COG0494	nUDIX hydrolase
Patl_0432	COG3151	Protein conserved in bacteria
Patl_0433	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Patl_0434	COG3150	esterase
Patl_0435	COG0187	DNA topoisomerase II activity
Patl_0440	COG1509	lysine 2,3-aminomutase activity
Patl_0443	COG3706	GGDEF domain
Patl_0447	COG2813	Specifically methylates the guanine in position
Patl_0449	COG0271	Belongs to the BolA IbaG family
Patl_0451	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Patl_0452	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Patl_0453	COG1805	sodium ion transport
Patl_0454	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Patl_0455	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Patl_0456	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Patl_0457	COG2871	sodium ion transport
Patl_0458	COG1477	protein flavinylation
Patl_0459	COG2991	Protein conserved in bacteria
Patl_0460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Patl_0464	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Patl_0465	COG3706	GGDEF domain
Patl_0467	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Patl_0468	COG0051	transcription antitermination factor activity, RNA binding
Patl_0469	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Patl_0470	COG0088	Forms part of the polypeptide exit tunnel
Patl_0471	COG0089	rRNA binding
Patl_0472	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Patl_0473	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Patl_0474	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Patl_0475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Patl_0476	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Patl_0477	COG0255	Belongs to the universal ribosomal protein uL29 family
Patl_0478	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Patl_0479	COG0793	Belongs to the peptidase S41A family
Patl_0481	COG0753	catalase activity
Patl_0482	COG2995	paraquat-inducible protein a
Patl_0486	COG0788	formyltetrahydrofolate deformylase activity
Patl_0488	COG1643	Atp-dependent helicase
Patl_0489	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Patl_0491	COG0347	Belongs to the P(II) protein family
Patl_0492	COG0004	ammonium transporteR
Patl_0493	COG2837	iron assimilation
Patl_0495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Patl_0496	COG0540	Belongs to the ATCase OTCase family
Patl_0500	COG1522	sequence-specific DNA binding
Patl_0512	COG1522	sequence-specific DNA binding
Patl_0513	COG0739	heme binding
Patl_0514	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Patl_0518	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Patl_0521	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Patl_0523	COG0784	Response regulator, receiver
Patl_0523	COG2205	protein histidine kinase activity
Patl_0525	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Patl_0527	COG3300	MHYT domain
Patl_0527	COG5001	Diguanylate cyclase
Patl_0528	COG0517	IMP dehydrogenase activity
Patl_0528	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Patl_0532	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Patl_0533	COG0572	uridine kinase
Patl_0538	COG1438	arginine binding
Patl_0539	COG0039	L-malate dehydrogenase activity
Patl_0544	COG0316	Belongs to the HesB IscA family
Patl_0546	COG0038	chloride channel
Patl_0548	COG0302	gtp cyclohydrolase
Patl_0549	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Patl_0550	COG0217	transcriptional regulatory protein
Patl_0551	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Patl_0553	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Patl_0554	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Patl_0555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Patl_0556	COG5007	Belongs to the BolA IbaG family
Patl_0558	COG2854	intermembrane phospholipid transfer
Patl_0559	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Patl_0560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Patl_0561	COG1127	ABC transporter
Patl_0563	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Patl_0563	COG0517	IMP dehydrogenase activity
Patl_0564	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Patl_0567	COG1137	ATPase activity
Patl_0568	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Patl_0570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Patl_0571	COG1660	Displays ATPase and GTPase activities
Patl_0572	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Patl_0577	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Patl_0580	COG3040	lipid binding
Patl_0582	COG2824	Alkylphosphonate utilization operon protein PhnA
Patl_0584	COG0418	dihydroorotase activity
Patl_0588	COG0513	Belongs to the DEAD box helicase family
Patl_0590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Patl_0591	COG1132	(ABC) transporter
Patl_0592	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Patl_0593	COG0250	Participates in transcription elongation, termination and antitermination
Patl_0594	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Patl_0595	COG0081	regulation of translation
Patl_0596	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Patl_0597	COG0222	ribosome binding
Patl_0598	COG0085	RNA polymerase activity
Patl_0599	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Patl_0600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Patl_0601	COG0049	tRNA binding
Patl_0602	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Patl_0603	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Patl_0605	COG1739	Uncharacterized protein family UPF0029
Patl_0606	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Patl_0607	COG0545	Peptidyl-prolyl cis-trans isomerase
Patl_0608	COG0659	secondary active sulfate transmembrane transporter activity
Patl_0611	COG2267	carboxylic ester hydrolase activity
Patl_0612	COG2095	MarC family integral membrane protein
Patl_0615	COG3706	GGDEF domain
Patl_0617	COG0514	ATP-dependent DNA helicase (RecQ)
Patl_0624	COG0028	Belongs to the TPP enzyme family
Patl_0626	COG1435	thymidine kinase activity
Patl_0629	COG3135	benzoate transporter
Patl_0630	COG0385	Bile acid
Patl_0636	COG0583	DNA-binding transcription factor activity
Patl_0637	COG0004	ammonium transporteR
Patl_0638	COG1404	Belongs to the peptidase S8 family
Patl_0643	COG0642	Histidine kinase
Patl_0645	COG2239	Acts as a magnesium transporter
Patl_0649	COG1012	belongs to the aldehyde dehydrogenase family
Patl_0651	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Patl_0656	COG1960	acyl-CoA dehydrogenase activity
Patl_0658	COG0180	Tryptophanyl-tRNA synthetase
Patl_0659	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Patl_0663	COG0338	D12 class N6 adenine-specific DNA methyltransferase
Patl_0665	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Patl_0666	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Patl_0694	COG4695	Portal protein
Patl_0723	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Patl_0724	COG0281	malic enzyme
Patl_0729	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Patl_0735	COG5002	protein histidine kinase activity
Patl_0736	COG1309	transcriptional regulator
Patl_0742	COG1764	response to oxidative stress
Patl_0746	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Patl_0746	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Patl_0754	COG2203	Gaf domain
Patl_0754	COG3706	GGDEF domain
Patl_0754	COG4251	negative regulation of phosphorylation
Patl_0754	COG5001	Diguanylate cyclase
Patl_0757	COG3264	Mechanosensitive ion channel
Patl_0757	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Patl_0758	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
Patl_0761	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Patl_0761	COG1672	PFAM Archaeal ATPase
Patl_0766	COG0753	catalase activity
Patl_0767	COG4771	TonB-dependent receptor
Patl_0768	COG0457	Tetratricopeptide repeat
Patl_0769	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_0770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Patl_0772	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Patl_0773	COG2207	Transcriptional regulator
Patl_0776	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Patl_0779	COG0246	Mannitol dehydrogenase
Patl_0780	COG0443	Heat shock 70 kDa protein
Patl_0785	COG4771	TonB-dependent receptor
Patl_0790	COG0295	cytidine deaminase activity
Patl_0793	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Patl_0794	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Patl_0795	COG3119	arylsulfatase activity
Patl_0797	COG1063	alcohol dehydrogenase
Patl_0798	COG3618	amidohydrolase
Patl_0800	COG2721	sulfolactate sulfo-lyase activity
Patl_0801	COG0738	Major facilitator superfamily
Patl_0804	COG3250	beta-galactosidase activity
Patl_0819	COG3119	arylsulfatase activity
Patl_0824	COG2273	Hydrolase Family 16
Patl_0825	COG1472	Belongs to the glycosyl hydrolase 3 family
Patl_0826	COG1368	sulfuric ester hydrolase activity
Patl_0832	COG3250	beta-galactosidase activity
Patl_0834	COG0246	Mannitol dehydrogenase
Patl_0836	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Patl_0839	COG3401	FG-GAP repeat protein
Patl_0850	COG1063	alcohol dehydrogenase
Patl_0855	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Patl_0859	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Patl_0865	COG4771	TonB-dependent receptor
Patl_0868	COG2259	Doxx family
Patl_0871	COG2375	cellular response to nickel ion
Patl_0872	COG0625	glutathione transferase activity
Patl_0888	COG3119	arylsulfatase activity
Patl_0889	COG3119	arylsulfatase activity
Patl_0892	COG0445	tRNA wobble uridine modification
Patl_0894	COG2186	Transcriptional regulator
Patl_0895	COG3119	arylsulfatase activity
Patl_0897	COG4948	Mandelate Racemase Muconate Lactonizing
Patl_0898	COG3734	2-keto-3-deoxy-galactonokinase
Patl_0899	COG0800	Aldolase
Patl_0900	COG2814	Major facilitator Superfamily
Patl_0901	COG2186	Transcriptional regulator
Patl_0906	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_0912	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_0921	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Patl_0922	COG2070	2-Nitropropane dioxygenase
Patl_0925	COG0850	regulation of cytokinetic process
Patl_0927	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Patl_0929	COG3228	Belongs to the MtfA family
Patl_0949	COG1960	acyl-CoA dehydrogenase activity
Patl_0950	COG1250	3-hydroxyacyl-CoA dehydrogenase
Patl_0950	COG1024	Enoyl-CoA hydratase
Patl_0952	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_0956	COG0121	glutamine amidotransferase
Patl_0961	COG2815	serine threonine protein kinase
Patl_0961	COG0515	serine threonine protein kinase
Patl_0968	COG0469	pyruvate kinase activity
Patl_0969	COG1737	Transcriptional regulator
Patl_0970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Patl_0971	COG0363	glucosamine-6-phosphate deaminase activity
Patl_0972	COG0129	dihydroxy-acid dehydratase activity
Patl_0973	COG0837	glucose binding
Patl_0974	COG0800	Aldolase
Patl_0977	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Patl_0977	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Patl_0978	COG0165	Argininosuccinate lyase
Patl_0979	COG0137	argininosuccinate synthase activity
Patl_0980	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Patl_0982	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Patl_0985	COG1803	Methylglyoxal synthase
Patl_0987	COG0745	RESPONSE REGULATOR receiver
Patl_0988	COG2205	protein histidine kinase activity
Patl_0989	COG2267	carboxylic ester hydrolase activity
Patl_0990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Patl_0993	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
Patl_0994	COG0557	exoribonuclease II activity
Patl_0995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Patl_0997	COG0583	DNA-binding transcription factor activity
Patl_0998	COG1022	Amp-dependent synthetase and ligase
Patl_0999	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Patl_1000	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Patl_1002	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Patl_1003	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Patl_1004	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Patl_1005	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Patl_1006	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Patl_1007	COG1841	ribosomal large subunit assembly
Patl_1008	COG0200	Binds to the 23S rRNA
Patl_1009	COG0201	protein transport
Patl_1010	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Patl_1011	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Patl_1012	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Patl_1013	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Patl_1014	COG0202	RNA polymerase activity
Patl_1015	COG0203	ribosomal protein L17
Patl_1019	COG1228	amidohydrolase
Patl_1020	COG2188	Transcriptional regulator
Patl_1022	COG2986	histidine ammonia-lyase
Patl_1023	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Patl_1025	COG0174	glutamine synthetase
Patl_1027	COG3852	Histidine kinase
Patl_1028	COG2204	response regulator
Patl_1029	COG3437	response regulator, receiver
Patl_1030	COG0204	Acyl-transferase
Patl_1031	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
Patl_1033	COG2356	endonuclease I
Patl_1035	COG1404	Belongs to the peptidase S8 family
Patl_1036	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Patl_1037	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Patl_1038	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Patl_1039	COG0358	DNA primase activity
Patl_1041	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Patl_1043	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Patl_1044	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Patl_1046	COG1968	undecaprenyl-diphosphatase activity
Patl_1047	COG0537	adenosine 5'-monophosphoramidase activity
Patl_1051	COG2974	May be involved in recombination
Patl_1052	COG4191	Histidine kinase
Patl_1052	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Patl_1053	COG0745	RESPONSE REGULATOR receiver
Patl_1054	COG5002	protein histidine kinase activity
Patl_1058	COG0672	)-iron permease
Patl_1061	COG0811	peptide transport
Patl_1062	COG0811	peptide transport
Patl_1063	COG0848	biopolymer transport protein
Patl_1064	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Patl_1066	COG0450	alkyl hydroperoxide reductase
Patl_1067	COG3634	alkyl hydroperoxide reductase activity
Patl_1074	COG4464	protein tyrosine phosphatase activity
Patl_1084	COG2755	lipolytic protein G-D-S-L family
Patl_1084	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Patl_1090	COG0438	transferase activity, transferring glycosyl groups
Patl_1092	COG1216	Glycosyl transferase, family 2
Patl_1096	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Patl_1096	COG2755	lipolytic protein G-D-S-L family
Patl_1104	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Patl_1109	COG1966	Carbon starvation protein
Patl_1110	COG4206	TonB-dependent receptor
Patl_1114	COG0508	dehydrogenase complex catalyzes the overall conversion of
Patl_1115	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Patl_1121	COG0583	DNA-binding transcription factor activity
Patl_1124	COG0346	lactoylglutathione lyase activity
Patl_1127	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Patl_1127	COG1017	nitric oxide dioxygenase activity
Patl_1128	COG0625	glutathione transferase activity
Patl_1131	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Patl_1134	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Patl_1135	COG1492	cobalamin metabolic process
Patl_1138	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Patl_1139	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Patl_1140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Patl_1141	COG1120	ATPase activity
Patl_1142	COG4774	siderophore transport
Patl_1149	COG3279	Response regulator of the LytR AlgR family
Patl_1150	COG3275	phosphorelay sensor kinase activity
Patl_1152	COG0189	ligase activity
Patl_1155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Patl_1156	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Patl_1157	COG2207	Transcriptional regulator
Patl_1157	COG0662	Cupin 2, conserved barrel domain protein
Patl_1161	COG3132	Protein of unknown function, DUF480
Patl_1162	COG0123	including yeast histone deacetylase and acetoin utilization protein
Patl_1164	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Patl_1166	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Patl_1166	COG0475	glutathione-regulated potassium exporter activity
Patl_1168	COG0489	protein tyrosine kinase activity
Patl_1179	COG1216	Glycosyl transferase, family 2
Patl_1186	COG1216	Glycosyl transferase, family 2
Patl_1188	COG0438	transferase activity, transferring glycosyl groups
Patl_1190	COG2244	polysaccharide biosynthetic process
Patl_1191	COG0438	transferase activity, transferring glycosyl groups
Patl_1193	COG0438	transferase activity, transferring glycosyl groups
Patl_1194	COG0367	asparagine synthase
Patl_1206	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Patl_1213	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Patl_1216	COG1785	Belongs to the alkaline phosphatase family
Patl_1218	COG0705	Rhomboid family
Patl_1219	COG0754	glutathionylspermidine amidase activity
Patl_1224	COG1842	Phage shock protein A
Patl_1227	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Patl_1228	COG0343	queuine tRNA-ribosyltransferase activity
Patl_1229	COG1862	Preprotein translocase
Patl_1230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Patl_1231	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Patl_1232	COG0483	inositol monophosphate 1-phosphatase activity
Patl_1233	COG0346	lactoylglutathione lyase activity
Patl_1235	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
Patl_1236	COG1045	serine acetyltransferase
Patl_1237	COG1959	2 iron, 2 sulfur cluster binding
Patl_1238	COG1104	cysteine desulfurase activity
Patl_1239	COG0822	iron-sulfur transferase activity
Patl_1240	COG0316	Belongs to the HesB IscA family
Patl_1241	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Patl_1242	COG0443	Heat shock 70 kDa protein
Patl_1247	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Patl_1248	COG0024	Methionine aminopeptidase
Patl_1249	COG0052	Belongs to the universal ribosomal protein uS2 family
Patl_1250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Patl_1251	COG0528	UMP kinase activity
Patl_1252	COG0233	cytoplasmic translational termination
Patl_1253	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Patl_1254	COG0575	Belongs to the CDS family
Patl_1255	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Patl_1259	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Patl_1260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Patl_1261	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Patl_1263	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Patl_1265	COG0825	malonyl-CoA metabolic process
Patl_1266	COG0037	tRNA processing
Patl_1272	COG2207	Transcriptional regulator
Patl_1273	COG4807	Protein conserved in bacteria
Patl_1276	COG0442	prolyl-tRNA aminoacylation
Patl_1277	COG1720	tRNA m6t6A37 methyltransferase activity
Patl_1278	COG0560	Phosphoserine phosphatase
Patl_1280	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Patl_1290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Patl_1294	COG0109	protoheme IX farnesyltransferase activity
Patl_1296	COG0488	(ABC) transporter
Patl_1299	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Patl_1310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Patl_1311	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Patl_1311	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Patl_1314	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Patl_1315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Patl_1317	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Patl_1318	COG1671	Belongs to the UPF0178 family
Patl_1319	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Patl_1320	COG0142	geranyltranstransferase activity
Patl_1321	COG1722	exodeoxyribonuclease VII activity
Patl_1322	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Patl_1323	COG1360	Flagellar Motor Protein
Patl_1326	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Patl_1329	COG4221	oxidoreductase activity
Patl_1332	COG1595	DNA-templated transcription, initiation
Patl_1334	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Patl_1335	COG0564	pseudouridine synthase activity
Patl_1337	COG0542	response to heat
Patl_1340	COG1183	phosphatidylcholine synthase activity
Patl_1341	COG1444	tRNA N-acetyltransferase activity
Patl_1349	COG0456	acetyltransferase
Patl_1356	COG0583	DNA-binding transcription factor activity
Patl_1358	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Patl_1359	COG0018	arginyl-trna synthetase
Patl_1360	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Patl_1361	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Patl_1362	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Patl_1363	COG0564	pseudouridine synthase activity
Patl_1365	COG0612	Peptidase, M16
Patl_1366	COG2918	glutathione biosynthetic process
Patl_1368	COG0318	PFAM AMP-dependent synthetase and ligase
Patl_1370	COG1024	Enoyl-CoA hydratase
Patl_1371	COG1902	pentaerythritol trinitrate reductase activity
Patl_1371	COG0446	pyridine nucleotide-disulphide oxidoreductase
Patl_1372	COG0583	DNA-binding transcription factor activity
Patl_1373	COG4989	oxidoreductase activity
Patl_1389	COG3112	Uncharacterised protein family (UPF0231)
Patl_1390	COG1451	nucleotide metabolic process
Patl_1391	COG4628	conserved protein (DUF2132)
Patl_1392	COG2719	SpoVR family
Patl_1393	COG2718	Belongs to the UPF0229 family
Patl_1394	COG2766	serine protein kinase
Patl_1396	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Patl_1397	COG2906	2 iron, 2 sulfur cluster binding
Patl_1398	COG0450	alkyl hydroperoxide reductase
Patl_1401	COG0584	glycerophosphoryl diester phosphodiesterase
Patl_1402	COG0346	lactoylglutathione lyase activity
Patl_1403	COG2076	Multidrug Resistance protein
Patl_1404	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Patl_1405	COG2130	NADP-dependent
Patl_1408	COG1960	acyl-CoA dehydrogenase activity
Patl_1413	COG2944	sequence-specific DNA binding
Patl_1418	COG1802	Transcriptional regulator
Patl_1419	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Patl_1420	COG0372	Belongs to the citrate synthase family
Patl_1421	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Patl_1422	COG2828	Protein conserved in bacteria
Patl_1423	COG2814	Major facilitator Superfamily
Patl_1424	COG2199	diguanylate cyclase activity
Patl_1424	COG2203	Gaf domain
Patl_1425	COG1902	pentaerythritol trinitrate reductase activity
Patl_1427	COG4303	Ethanolamine ammonia lyase large subunit
Patl_1428	COG4302	ethanolamine ammonia-lyase activity
Patl_1432	COG4221	oxidoreductase activity
Patl_1434	COG0069	glutamate synthase activity
Patl_1436	COG0583	DNA-binding transcription factor activity
Patl_1440	COG0583	DNA-binding transcription factor activity
Patl_1445	COG2031	fatty acid transporter
Patl_1446	COG3781	membrane
Patl_1447	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Patl_1451	COG1280	lysine exporter protein (LysE YggA)
Patl_1453	COG1294	oxidase, subunit
Patl_1454	COG4890	Cyd operon protein YbgT
Patl_1455	COG4988	ABC transporter
Patl_1456	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Patl_1462	COG1024	Enoyl-CoA hydratase
Patl_1467	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Patl_1471	COG0024	Methionine aminopeptidase
Patl_1478	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Patl_1479	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Patl_1480	COG1522	sequence-specific DNA binding
Patl_1481	COG1454	alcohol dehydrogenase
Patl_1483	COG1280	lysine exporter protein (LysE YggA)
Patl_1485	COG0436	Aminotransferase
Patl_1486	COG4771	TonB-dependent receptor
Patl_1488	COG4558	Periplasmic binding protein
Patl_1489	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Patl_1497	COG0583	DNA-binding transcription factor activity
Patl_1506	COG1012	belongs to the aldehyde dehydrogenase family
Patl_1507	COG2814	Major facilitator Superfamily
Patl_1509	COG2188	Transcriptional regulator
Patl_1512	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Patl_1513	COG0154	amidase activity
Patl_1516	COG0583	DNA-binding transcription factor activity
Patl_1518	COG1473	amidohydrolase
Patl_1522	COG1595	DNA-templated transcription, initiation
Patl_1524	COG0500	methyltransferase
Patl_1527	COG0745	RESPONSE REGULATOR receiver
Patl_1528	COG2205	protein histidine kinase activity
Patl_1535	COG3852	Histidine kinase
Patl_1540	COG2890	protein-(glutamine-N5) methyltransferase activity
Patl_1541	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Patl_1543	COG1278	Cold shock
Patl_1544	COG0252	asparaginase activity
Patl_1546	COG0412	Dienelactone hydrolase
Patl_1547	COG3123	guanosine phosphorylase activity
Patl_1552	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Patl_1553	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Patl_1554	COG0321	lipoyl(octanoyl) transferase activity
Patl_1555	COG2921	Belongs to the UPF0250 family
Patl_1556	COG1686	Belongs to the peptidase S11 family
Patl_1557	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Patl_1558	COG2951	lytic endotransglycosylase activity
Patl_1559	COG0772	Belongs to the SEDS family
Patl_1560	COG0768	penicillin binding
Patl_1561	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Patl_1562	COG0799	negative regulation of ribosome biogenesis
Patl_1563	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Patl_1566	COG0495	leucyl-tRNA aminoacylation
Patl_1567	COG1067	ATP-dependent peptidase activity
Patl_1569	COG1534	Rna-binding protein
Patl_1570	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Patl_1571	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Patl_1572	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Patl_1573	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Patl_1574	COG0149	triose-phosphate isomerase activity
Patl_1575	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Patl_1576	COG3842	ATPase activity
Patl_1577	COG0228	four-way junction DNA binding
Patl_1578	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Patl_1579	COG0336	Belongs to the RNA methyltransferase TrmD family
Patl_1580	COG0335	large ribosomal subunit rRNA binding
Patl_1582	COG0789	Transcriptional regulator
Patl_1583	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
Patl_1584	COG0110	maltose O-acetyltransferase activity
Patl_1586	COG0339	signal peptide processing
Patl_1587	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Patl_1588	COG1605	Chorismate mutase
Patl_1588	COG0287	Prephenate dehydrogenase
Patl_1590	COG1605	Chorismate mutase
Patl_1590	COG0077	Prephenate dehydratase
Patl_1591	COG0745	RESPONSE REGULATOR receiver
Patl_1592	COG0023	Translation Initiation Factor
Patl_1594	COG0745	RESPONSE REGULATOR receiver
Patl_1596	COG1840	ABC-type Fe3 transport system, periplasmic component
Patl_1597	COG1178	ABC-type Fe3 transport system permease component
Patl_1598	COG3842	ATPase activity
Patl_1601	COG2205	protein histidine kinase activity
Patl_1603	COG2204	response regulator
Patl_1604	COG0101	tRNA pseudouridine synthase activity
Patl_1605	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Patl_1606	COG0285	dihydrofolate synthase activity
Patl_1607	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
Patl_1608	COG1286	toxin biosynthetic process
Patl_1609	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Patl_1611	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Patl_1612	COG1129	ABC transporter
Patl_1612	COG0842	Transport permease protein
Patl_1613	COG0842	Transport permease protein
Patl_1616	COG2259	Doxx family
Patl_1617	COG0778	Nitroreductase
Patl_1618	COG0513	Belongs to the DEAD box helicase family
Patl_1620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Patl_1621	COG0583	DNA-binding transcription factor activity
Patl_1625	COG1760	l-serine dehydratase
Patl_1627	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Patl_1629	COG1322	Protein conserved in bacteria
Patl_1630	COG0564	pseudouridine synthase activity
Patl_1632	COG1185	polyribonucleotide nucleotidyltransferase activity
Patl_1633	COG0676	glucose-6-phosphate 1-epimerase activity
Patl_1634	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Patl_1635	COG1640	4-alpha-glucanotransferase
Patl_1636	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Patl_1641	COG2866	Carboxypeptidase
Patl_1642	COG1115	amino acid carrier protein
Patl_1644	COG3139	Protein of unknown function (DUF1315)
Patl_1646	COG1187	pseudouridine synthase activity
Patl_1647	COG3273	potassium ion transport
Patl_1647	COG0471	metal ion transport
Patl_1648	COG2895	sulfate adenylyltransferase (ATP) activity
Patl_1649	COG1218	3'(2'),5'-bisphosphate nucleotidase
Patl_1650	COG0529	Catalyzes the synthesis of activated sulfate
Patl_1651	COG0175	sulfate reduction
Patl_1652	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Patl_1653	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Patl_1654	COG2153	protein acetylation
Patl_1656	COG1595	DNA-templated transcription, initiation
Patl_1658	COG2304	oxidoreductase activity
Patl_1662	COG0714	Associated with various cellular activities
Patl_1663	COG0183	Belongs to the thiolase family
Patl_1664	COG1250	3-hydroxyacyl-CoA dehydrogenase
Patl_1664	COG1024	Enoyl-CoA hydratase
Patl_1666	COG0612	Peptidase, M16
Patl_1667	COG2062	phosphohistidine phosphatase, SixA
Patl_1668	COG4536	flavin adenine dinucleotide binding
Patl_1669	COG4137	Cytochrome C assembly protein
Patl_1670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Patl_1673	COG0583	DNA-binding transcription factor activity
Patl_1674	COG2130	NADP-dependent
Patl_1675	COG0583	DNA-binding transcription factor activity
Patl_1676	COG1741	Belongs to the pirin family
Patl_1679	COG2234	aminopeptidase activity
Patl_1682	COG3706	GGDEF domain
Patl_1684	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Patl_1686	COG4948	Mandelate Racemase Muconate Lactonizing
Patl_1688	COG1960	acyl-CoA dehydrogenase activity
Patl_1691	COG4771	TonB-dependent receptor
Patl_1693	COG0779	Required for maturation of 30S ribosomal subunits
Patl_1694	COG0195	Participates in both transcription termination and antitermination
Patl_1695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Patl_1696	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Patl_1697	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Patl_1698	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Patl_1700	COG3530	Putative quorum-sensing-regulated virulence factor
Patl_1701	COG5265	(ABC) transporter
Patl_1702	COG3706	GGDEF domain
Patl_1704	COG3008	intermembrane lipid transfer
Patl_1704	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Patl_1705	COG2995	paraquat-inducible protein a
Patl_1706	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Patl_1707	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Patl_1712	COG0488	(ABC) transporter
Patl_1713	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Patl_1714	COG0497	DNA recombination
Patl_1715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Patl_1716	COG1472	Belongs to the glycosyl hydrolase 3 family
Patl_1717	COG0471	metal ion transport
Patl_1719	COG0583	DNA-binding transcription factor activity
Patl_1725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Patl_1727	COG4591	ABC-type transport system involved in lipoprotein release permease component
Patl_1730	COG2315	Protein conserved in bacteria
Patl_1739	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Patl_1740	COG2867	negative regulation of translational initiation
Patl_1741	COG2914	Belongs to the UPF0125 (RnfH) family
Patl_1743	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Patl_1744	COG0574	Belongs to the PEP-utilizing enzyme family
Patl_1744	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Patl_1746	COG0247	lactate metabolic process
Patl_1746	COG0277	FAD linked oxidase domain protein
Patl_1747	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Patl_1748	COG0427	acetyl-CoA hydrolase
Patl_1750	COG5002	protein histidine kinase activity
Patl_1756	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Patl_1757	COG1074	ATP-dependent DNA helicase activity
Patl_1758	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Patl_1762	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Patl_1769	COG2199	diguanylate cyclase activity
Patl_1769	COG2203	Gaf domain
Patl_1771	COG0745	RESPONSE REGULATOR receiver
Patl_1771	COG3706	GGDEF domain
Patl_1772	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Patl_1774	COG1196	nuclear chromosome segregation
Patl_1776	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Patl_1779	COG2333	competence protein COMEC
Patl_1779	COG0658	competence protein
Patl_1780	COG1132	(ABC) transporter
Patl_1781	COG1663	tetraacyldisaccharide 4'-kinase activity
Patl_1782	COG2835	tetraacyldisaccharide 4'-kinase activity
Patl_1783	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Patl_1785	COG3706	GGDEF domain
Patl_1789	COG0583	DNA-binding transcription factor activity
Patl_1791	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Patl_1794	COG0372	Belongs to the citrate synthase family
Patl_1795	COG2009	succinate dehydrogenase
Patl_1796	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Patl_1797	COG1053	succinate dehydrogenase
Patl_1799	COG0567	Dehydrogenase, E1 component
Patl_1800	COG0508	dehydrogenase complex catalyzes the overall conversion of
Patl_1801	COG0045	succinate-CoA ligase (ADP-forming) activity
Patl_1808	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Patl_1809	COG3340	Belongs to the peptidase S51 family
Patl_1810	COG4771	TonB-dependent receptor
Patl_1812	COG1960	acyl-CoA dehydrogenase activity
Patl_1828	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Patl_1829	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Patl_1834	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Patl_1836	COG5002	protein histidine kinase activity
Patl_1837	COG1620	l-lactate permease
Patl_1841	COG3119	arylsulfatase activity
Patl_1842	COG3119	arylsulfatase activity
Patl_1843	COG4974	Belongs to the 'phage' integrase family
Patl_1863	COG4206	TonB-dependent receptor
Patl_1866	COG1116	anion transmembrane transporter activity
Patl_1871	COG2205	protein histidine kinase activity
Patl_1871	COG0784	Response regulator, receiver
Patl_1873	COG3901	Regulator of nitric oxide reductase transcription
Patl_1873	COG0348	domain, Protein
Patl_1875	COG0702	epimerase
Patl_1879	COG0017	Asparaginyl-tRNA synthetase
Patl_1883	COG1522	sequence-specific DNA binding
Patl_1884	COG1757	Na H antiporter
Patl_1886	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Patl_1887	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Patl_1888	COG0215	cysteine-tRNA ligase activity
Patl_1894	COG0741	lytic transglycosylase activity
Patl_1894	COG1388	LysM domain
Patl_1895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Patl_1896	COG2226	methyltransferase
Patl_1897	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Patl_1897	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Patl_1899	COG0717	Belongs to the dCTP deaminase family
Patl_1906	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Patl_1909	COG2207	Transcriptional regulator
Patl_1910	COG2807	transmembrane transport
Patl_1911	COG1012	belongs to the aldehyde dehydrogenase family
Patl_1914	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_1915	COG0596	Alpha beta hydrolase
Patl_1917	COG0183	Belongs to the thiolase family
Patl_1918	COG1960	acyl-CoA dehydrogenase activity
Patl_1919	COG0596	Alpha beta hydrolase
Patl_1920	COG3706	GGDEF domain
Patl_1927	COG0477	Major facilitator Superfamily
Patl_1928	COG1902	pentaerythritol trinitrate reductase activity
Patl_1931	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Patl_1934	COG2022	thiamine diphosphate biosynthetic process
Patl_1935	COG0352	thiamine-phosphate diphosphorylase activity
Patl_1936	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Patl_1954	COG3171	Protein conserved in bacteria
Patl_1969	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Patl_1970	COG2814	Major facilitator Superfamily
Patl_1975	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Patl_1976	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_1978	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Patl_1979	COG2610	gluconate transmembrane transporter activity
Patl_1985	COG0784	Response regulator, receiver
Patl_1985	COG2205	protein histidine kinase activity
Patl_1985	COG5002	protein histidine kinase activity
Patl_1986	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Patl_1987	COG0443	Heat shock 70 kDa protein
Patl_1988	COG0484	heat shock protein binding
Patl_1990	COG1956	GAF domain-containing protein
Patl_1992	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
Patl_1993	COG0793	Belongs to the peptidase S41A family
Patl_1994	COG0733	neurotransmitter:sodium symporter activity
Patl_1996	COG0308	aminopeptidase N
Patl_2002	COG2902	Dehydrogenase
Patl_2003	COG0167	dihydroorotate dehydrogenase activity
Patl_2005	COG0116	Belongs to the methyltransferase superfamily
Patl_2005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Patl_2008	COG3130	regulation of translation
Patl_2009	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Patl_2011	COG3012	SEC-C Motif Domain Protein
Patl_2014	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Patl_2015	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Patl_2017	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Patl_2019	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Patl_2024	COG0789	Transcriptional regulator
Patl_2025	COG1230	cation diffusion facilitator family transporter
Patl_2032	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Patl_2033	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Patl_2034	COG0436	Aminotransferase
Patl_2037	COG0022	dehydrogenase e1 component
Patl_2039	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Patl_2040	COG0515	serine threonine protein kinase
Patl_2041	COG1946	Acyl-CoA thioesterase
Patl_2043	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Patl_2046	COG1119	ATPase activity
Patl_2048	COG2066	Belongs to the glutaminase family
Patl_2052	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Patl_2053	COG0730	response to heat
Patl_2059	COG1280	lysine exporter protein (LysE YggA)
Patl_2063	COG1752	Esterase of the alpha-beta hydrolase superfamily
Patl_2064	COG0037	tRNA processing
Patl_2068	COG2217	Heavy metal translocating P-type atpase
Patl_2070	COG2010	Cytochrome c
Patl_2073	COG3278	Belongs to the heme-copper respiratory oxidase family
Patl_2075	COG2193	ferroxidase activity
Patl_2078	COG0668	transmembrane transport
Patl_2084	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Patl_2085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Patl_2088	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Patl_2089	COG3706	GGDEF domain
Patl_2089	COG4251	negative regulation of phosphorylation
Patl_2089	COG5001	Diguanylate cyclase
Patl_2089	COG2203	Gaf domain
Patl_2091	COG2217	Heavy metal translocating P-type atpase
Patl_2094	COG0589	response to stress
Patl_2096	COG4566	intracellular signal transduction
Patl_2097	COG4191	Histidine kinase
Patl_2099	COG0789	Transcriptional regulator
Patl_2100	COG0484	heat shock protein binding
Patl_2102	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Patl_2102	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Patl_2103	COG0589	response to stress
Patl_2104	COG0784	Response regulator, receiver
Patl_2104	COG5002	protein histidine kinase activity
Patl_2104	COG2205	protein histidine kinase activity
Patl_2105	COG0640	Transcriptional regulator
Patl_2110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Patl_2112	COG4993	Dehydrogenase
Patl_2115	COG0084	hydrolase, TatD family'
Patl_2118	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Patl_2120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Patl_2121	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Patl_2123	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Patl_2124	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Patl_2125	COG0416	fatty acid biosynthetic process
Patl_2126	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Patl_2127	COG1399	metal-binding, possibly nucleic acid-binding protein
Patl_2128	COG0424	maF-like protein
Patl_2131	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Patl_2133	COG0564	pseudouridine synthase activity
Patl_2134	COG1530	ribonuclease E activity
Patl_2135	COG0513	Belongs to the DEAD box helicase family
Patl_2136	COG2911	Protein conserved in bacteria
Patl_2138	COG3784	Protein of unknown function (DUF1318)
Patl_2139	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_2140	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_2141	COG1960	acyl-CoA dehydrogenase activity
Patl_2143	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Patl_2151	COG0716	FMN binding
Patl_2152	COG0735	belongs to the Fur family
Patl_2155	COG0314	molybdopterin synthase activity
Patl_2156	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Patl_2157	COG0315	cyclic pyranopterin monophosphate synthase activity
Patl_2158	COG0521	Mo-molybdopterin cofactor biosynthetic process
Patl_2159	COG0746	molybdenum cofactor guanylyltransferase activity
Patl_2160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Patl_2163	COG1215	transferase activity, transferring glycosyl groups
Patl_2167	COG3321	synthase
Patl_2167	COG0604	alcohol dehydrogenase
Patl_2168	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Patl_2170	COG1643	Atp-dependent helicase
Patl_2172	COG2925	Exonuclease
Patl_2175	COG2084	Dehydrogenase
Patl_2176	COG0386	Belongs to the glutathione peroxidase family
Patl_2177	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Patl_2178	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Patl_2179	COG0415	Belongs to the DNA photolyase family
Patl_2181	COG0616	signal peptide processing
Patl_2182	COG2267	carboxylic ester hydrolase activity
Patl_2183	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_2184	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Patl_2185	COG1609	Transcriptional regulator
Patl_2191	COG1393	Belongs to the ArsC family
Patl_2192	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Patl_2193	COG1876	peptidase activity
Patl_2194	COG0393	Putative heavy-metal-binding
Patl_2195	COG2988	succinylglutamate desuccinylase activity
Patl_2197	COG0058	SHG alpha-glucan phosphorylase activity
Patl_2198	COG0033	Phosphoglucomutase
Patl_2199	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
Patl_2200	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
Patl_2201	COG2363	Small membrane protein
Patl_2203	COG0583	DNA-binding transcription factor activity
Patl_2206	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Patl_2207	COG1702	phosphate starvation-inducible protein PhoH
Patl_2208	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Patl_2209	COG4535	Mg2 and Co2 transporter CorC
Patl_2210	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Patl_2211	COG0697	spore germination
Patl_2212	COG0693	protein deglycase activity
Patl_2213	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Patl_2214	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Patl_2215	COG0505	Belongs to the CarA family
Patl_2216	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Patl_2218	COG0506	proline dehydrogenase activity
Patl_2218	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Patl_2218	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Patl_2222	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Patl_2223	COG2233	PERMEase
Patl_2229	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Patl_2232	COG0667	Aldo Keto reductase
Patl_2234	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Patl_2235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Patl_2236	COG0243	molybdopterin cofactor binding
Patl_2237	COG3813	Protein conserved in bacteria
Patl_2239	COG0577	efflux transmembrane transporter activity
Patl_2239	COG1136	(ABC) transporter
Patl_2246	COG5001	Diguanylate cyclase
Patl_2246	COG1716	ATPase activity
Patl_2247	COG0840	transmembrane signaling receptor activity
Patl_2248	COG3437	response regulator, receiver
Patl_2251	COG0745	RESPONSE REGULATOR receiver
Patl_2255	COG0667	Aldo Keto reductase
Patl_2256	COG2207	Transcriptional regulator
Patl_2257	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Patl_2257	COG3264	Mechanosensitive ion channel
Patl_2267	COG2610	gluconate transmembrane transporter activity
Patl_2269	COG0210	DNA helicase
Patl_2273	COG3128	pkhd-type hydroxylase
Patl_2275	COG4774	siderophore transport
Patl_2279	COG0811	peptide transport
Patl_2282	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Patl_2283	COG5507	3-demethylubiquinone-9 3-methyltransferase
Patl_2284	COG4651	solute:proton antiporter activity
Patl_2284	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Patl_2285	COG0589	response to stress
Patl_2289	COG1280	lysine exporter protein (LysE YggA)
Patl_2292	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Patl_2301	COG0745	RESPONSE REGULATOR receiver
Patl_2302	COG2205	protein histidine kinase activity
Patl_2302	COG3437	response regulator, receiver
Patl_2302	COG4999	Histidine kinase
Patl_2302	COG3850	Histidine kinase
Patl_2305	COG2124	cytochrome p450
Patl_2309	COG0681	Belongs to the peptidase S26 family
Patl_2310	COG3706	GGDEF domain
Patl_2312	COG0583	DNA-binding transcription factor activity
Patl_2313	COG0745	RESPONSE REGULATOR receiver
Patl_2322	COG3246	L-lysine catabolic process to acetate
Patl_2328	COG0564	pseudouridine synthase activity
Patl_2329	COG2814	Major facilitator Superfamily
Patl_2330	COG0513	Belongs to the DEAD box helicase family
Patl_2335	COG1418	mRNA catabolic process
Patl_2338	COG1501	Belongs to the glycosyl hydrolase 31 family
Patl_2339	COG2819	hydrolase of the alpha beta superfamily
Patl_2345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Patl_2355	COG3122	Protein conserved in bacteria
Patl_2356	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Patl_2357	COG3724	N-succinylarginine dihydrolase activity
Patl_2359	COG1301	dicarboxylic acid transport
Patl_2360	COG4591	ABC-type transport system involved in lipoprotein release permease component
Patl_2361	COG1136	(ABC) transporter
Patl_2362	COG1253	flavin adenine dinucleotide binding
Patl_2364	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Patl_2365	COG0328	RNA-DNA hybrid ribonuclease activity
Patl_2367	COG0616	signal peptide processing
Patl_2368	COG3091	SprT-like family
Patl_2369	COG3092	negative regulation of chromosome organization
Patl_2370	COG0492	ferredoxin-NADP+ reductase activity
Patl_2371	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Patl_2372	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Patl_2373	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Patl_2374	COG0542	response to heat
Patl_2375	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Patl_2376	COG1278	Cold shock
Patl_2378	COG1187	pseudouridine synthase activity
Patl_2379	COG0482	sulfurtransferase activity
Patl_2381	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Patl_2383	COG2850	peptidyl-arginine hydroxylation
Patl_2385	COG3279	Response regulator of the LytR AlgR family
Patl_2386	COG3275	phosphorelay sensor kinase activity
Patl_2389	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Patl_2390	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Patl_2391	COG1064	alcohol dehydrogenase
Patl_2392	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Patl_2393	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Patl_2397	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Patl_2399	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Patl_2400	COG0446	pyridine nucleotide-disulphide oxidoreductase
Patl_2400	COG1902	pentaerythritol trinitrate reductase activity
Patl_2406	COG1136	(ABC) transporter
Patl_2408	COG0577	efflux transmembrane transporter activity
Patl_2408	COG1136	(ABC) transporter
Patl_2409	COG2119	membrane
Patl_2415	COG1116	anion transmembrane transporter activity
Patl_2417	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Patl_2417	COG1116	anion transmembrane transporter activity
Patl_2419	COG2223	nitrite transmembrane transporter activity
Patl_2420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Patl_2421	COG2252	PERMEase
Patl_2423	COG1309	transcriptional regulator
Patl_2425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Patl_2428	COG2351	hydroxyisourate hydrolase activity
Patl_2429	COG0402	S-adenosylhomocysteine deaminase activity
Patl_2431	COG2808	Putative FMN-binding domain
Patl_2433	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Patl_2434	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Patl_2438	COG0513	Belongs to the DEAD box helicase family
Patl_2449	COG0322	excinuclease ABC activity
Patl_2450	COG2197	response regulator
Patl_2451	COG0670	Belongs to the BI1 family
Patl_2452	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Patl_2453	COG2923	Belongs to the DsrF TusC family
Patl_2455	COG2920	part of a sulfur-relay system
Patl_2456	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Patl_2457	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Patl_2458	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Patl_2460	COG1674	ftsk spoiiie
Patl_2460	COG0531	amino acid
Patl_2461	COG1522	sequence-specific DNA binding
Patl_2462	COG0686	Belongs to the AlaDH PNT family
Patl_2463	COG0284	orotidine-5'-phosphate decarboxylase activity
Patl_2464	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Patl_2465	COG0776	regulation of translation
Patl_2466	COG0539	negative regulation of cytoplasmic translation
Patl_2467	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Patl_2468	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Patl_2469	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Patl_2471	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Patl_2473	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Patl_2475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Patl_2476	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Patl_2477	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Patl_2478	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Patl_2480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Patl_2482	COG4783	chaperone-mediated protein folding
Patl_2484	COG1393	Belongs to the ArsC family
Patl_2487	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Patl_2489	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Patl_2490	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Patl_2492	COG1960	acyl-CoA dehydrogenase activity
Patl_2493	COG0776	regulation of translation
Patl_2494	COG0072	phenylalanine-tRNA ligase activity
Patl_2494	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Patl_2495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Patl_2496	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Patl_2497	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Patl_2498	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Patl_2505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Patl_2513	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Patl_2516	COG3604	Transcriptional regulator
Patl_2517	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Patl_2519	COG3214	Protein conserved in bacteria
Patl_2524	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Patl_2527	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Patl_2528	COG1116	anion transmembrane transporter activity
Patl_2528	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Patl_2529	COG2197	response regulator
Patl_2530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Patl_2532	COG0243	molybdopterin cofactor binding
Patl_2533	COG2146	nitrite reductase [NAD(P)H] activity
Patl_2534	COG2146	nitrite reductase [NAD(P)H] activity
Patl_2534	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Patl_2536	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Patl_2537	COG0303	'Molybdopterin
Patl_2538	COG0534	Mate efflux family protein
Patl_2550	COG4948	Mandelate Racemase Muconate Lactonizing
Patl_2551	COG1063	alcohol dehydrogenase
Patl_2552	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_2553	COG1012	belongs to the aldehyde dehydrogenase family
Patl_2555	COG2226	methyltransferase
Patl_2556	COG0156	8-amino-7-oxononanoate synthase activity
Patl_2557	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Patl_2560	COG3094	Invasion gene expression up-regulator, SirB
Patl_2561	COG0784	Response regulator, receiver
Patl_2561	COG3437	response regulator, receiver
Patl_2562	COG2890	protein-(glutamine-N5) methyltransferase activity
Patl_2563	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Patl_2564	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Patl_2566	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Patl_2567	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Patl_2568	COG0668	transmembrane transport
Patl_2569	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Patl_2570	COG0193	aminoacyl-tRNA hydrolase activity
Patl_2575	COG1115	amino acid carrier protein
Patl_2578	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Patl_2579	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Patl_2579	COG2205	protein histidine kinase activity
Patl_2588	COG1012	belongs to the aldehyde dehydrogenase family
Patl_2589	COG1309	transcriptional regulator
Patl_2590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Patl_2591	COG0280	phosphate acetyltransferase
Patl_2591	COG0857	belongs to the CobB CobQ family
Patl_2592	COG0205	6-phosphofructokinase activity
Patl_2593	COG0588	phosphoglycerate mutase activity
Patl_2594	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Patl_2594	COG0574	Belongs to the PEP-utilizing enzyme family
Patl_2596	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Patl_2599	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Patl_2608	COG0805	protein transport
Patl_2609	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Patl_2613	COG4667	esterase of the alpha-beta hydrolase superfamily
Patl_2616	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Patl_2623	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Patl_2624	COG4638	Rieske (2fe-2S)
Patl_2628	COG1278	Cold shock
Patl_2638	COG1309	transcriptional regulator
Patl_2639	COG0604	alcohol dehydrogenase
Patl_2641	COG3386	PFAM SMP-30 Gluconolaconase
Patl_2643	COG0800	Aldolase
Patl_2645	COG2271	Major facilitator Superfamily
Patl_2646	COG4948	Mandelate Racemase Muconate Lactonizing
Patl_2648	COG0708	Exodeoxyribonuclease III
Patl_2661	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Patl_2665	COG5001	Diguanylate cyclase
Patl_2666	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Patl_2667	COG0598	Magnesium transport protein CorA
Patl_2668	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Patl_2672	COG0356	it plays a direct role in the translocation of protons across the membrane
Patl_2674	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Patl_2675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Patl_2676	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Patl_2681	COG1609	Transcriptional regulator
Patl_2688	COG2211	Major facilitator Superfamily
Patl_2690	COG0673	inositol 2-dehydrogenase activity
Patl_2691	COG1609	Transcriptional regulator
Patl_2695	COG3119	arylsulfatase activity
Patl_2696	COG0454	-acetyltransferase
Patl_2699	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Patl_2701	COG4774	siderophore transport
Patl_2704	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Patl_2705	COG0596	Alpha beta hydrolase
Patl_2711	COG4771	TonB-dependent receptor
Patl_2714	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Patl_2717	COG2301	Belongs to the HpcH HpaI aldolase family
Patl_2719	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_2721	COG4115	mRNA cleavage
Patl_2723	COG1560	Kdo2-lipid A biosynthetic process
Patl_2730	COG2226	methyltransferase
Patl_2732	COG1335	isochorismatase
Patl_2752	COG1250	3-hydroxyacyl-CoA dehydrogenase
Patl_2752	COG1024	Enoyl-CoA hydratase
Patl_2756	COG4771	TonB-dependent receptor
Patl_2759	COG2130	NADP-dependent
Patl_2762	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Patl_2763	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Patl_2765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Patl_2767	COG0277	FAD linked oxidase domain protein
Patl_2772	COG0778	Nitroreductase
Patl_2775	COG1136	(ABC) transporter
Patl_2775	COG0577	efflux transmembrane transporter activity
Patl_2778	COG3608	succinylglutamate desuccinylase aspartoacylase
Patl_2779	COG0189	ligase activity
Patl_2782	COG1505	serine-type exopeptidase activity
Patl_2786	COG0339	signal peptide processing
Patl_2787	COG1473	amidohydrolase
Patl_2788	COG0583	DNA-binding transcription factor activity
Patl_2790	COG4948	Mandelate Racemase Muconate Lactonizing
Patl_2794	COG2186	Transcriptional regulator
Patl_2795	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Patl_2796	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Patl_2797	COG3046	protein related to deoxyribodipyrimidine photolyase
Patl_2798	COG2983	Belongs to the UPF0260 family
Patl_2800	COG0179	Fumarylacetoacetate (FAA) hydrolase
Patl_2801	COG2951	lytic endotransglycosylase activity
Patl_2802	COG3100	YcgL domain-containing protein
Patl_2803	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Patl_2804	COG0318	PFAM AMP-dependent synthetase and ligase
Patl_2808	COG1214	PFAM Peptidase M22, glycoprotease
Patl_2809	COG1199	ATP-dependent helicase activity
Patl_2810	COG0366	Alpha amylase catalytic
Patl_2812	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Patl_2814	COG0653	protein targeting
Patl_2815	COG2040	homocysteine
Patl_2824	COG1187	pseudouridine synthase activity
Patl_2825	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Patl_2827	COG0009	L-threonylcarbamoyladenylate synthase
Patl_2828	COG0613	PHP domain protein
Patl_2829	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Patl_2830	COG0512	Glutamine amidotransferase of anthranilate synthase
Patl_2831	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Patl_2832	COG0135	phosphoribosylanthranilate isomerase activity
Patl_2832	COG0134	indole-3-glycerol-phosphate synthase activity
Patl_2833	COG0133	tryptophan synthase activity
Patl_2835	COG2350	Protein conserved in bacteria
Patl_2840	COG0745	RESPONSE REGULATOR receiver
Patl_2842	COG0668	transmembrane transport
Patl_2845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Patl_2849	COG1234	tRNA 3'-trailer cleavage
Patl_2857	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Patl_2860	COG2188	Transcriptional regulator
Patl_2862	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Patl_2863	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Patl_2865	COG4771	TonB-dependent receptor
Patl_2868	COG0789	Transcriptional regulator
Patl_2870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Patl_2872	COG1309	transcriptional regulator
Patl_2875	COG2855	membrane
Patl_2877	COG0656	L-ascorbic acid biosynthetic process
Patl_2880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Patl_2881	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Patl_2882	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Patl_2883	COG0131	Imidazoleglycerol-phosphate dehydratase
Patl_2883	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Patl_2884	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Patl_2885	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Patl_2886	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Patl_2887	COG0107	imidazoleglycerol-phosphate synthase activity
Patl_2888	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Patl_2888	COG0140	phosphoribosyl-ATP diphosphatase activity
Patl_2889	COG3038	cytochrome b561
Patl_2890	COG2353	YceI-like domain
Patl_2892	COG3788	relative of glutathione S-transferase, MAPEG superfamily
Patl_2893	COG0563	adenylate kinase activity
Patl_2894	COG0326	Molecular chaperone. Has ATPase activity
Patl_2895	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Patl_2897	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Patl_2898	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Patl_2900	COG3220	belongs to the UPF0276 family
Patl_2903	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Patl_2908	COG0523	cobalamin synthesis protein
Patl_2909	COG0628	permease
Patl_2910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Patl_2911	COG1090	epimerase
Patl_2912	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Patl_2913	COG4181	ATPase activity
Patl_2914	COG2755	lipolytic protein G-D-S-L family
Patl_2915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Patl_2916	COG4269	membrane
Patl_2919	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Patl_2920	COG0745	RESPONSE REGULATOR receiver
Patl_2925	COG1960	acyl-CoA dehydrogenase activity
Patl_2926	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Patl_2927	COG1024	Enoyl-CoA hydratase
Patl_2932	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Patl_2934	COG2814	Major facilitator Superfamily
Patl_2936	COG1639	'signal transduction protein
Patl_2937	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Patl_2938	COG2885	chlorophyll binding
Patl_2939	COG0823	Involved in the tonB-independent uptake of proteins
Patl_2942	COG0811	peptide transport
Patl_2943	COG0824	Thioesterase
Patl_2944	COG2255	four-way junction helicase activity
Patl_2945	COG0632	four-way junction helicase activity
Patl_2946	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Patl_2947	COG0494	nUDIX hydrolase
Patl_2948	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Patl_2950	COG1668	transmembrane transport
Patl_2951	COG4555	ABC transporter
Patl_2955	COG0367	asparagine synthase
Patl_2956	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_2957	COG0604	alcohol dehydrogenase
Patl_2960	COG0602	queuosine metabolic process
Patl_2961	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Patl_2963	COG0556	nucleotide-excision repair
Patl_2965	COG4657	Part of a membrane complex involved in electron transport
Patl_2966	COG2878	Part of a membrane complex involved in electron transport
Patl_2968	COG4658	electron transport chain
Patl_2969	COG4659	FMN binding
Patl_2970	COG4660	Part of a membrane complex involved in electron transport
Patl_2971	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Patl_2974	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Patl_2979	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Patl_2980	COG4895	conserved protein (DUF2196)
Patl_2987	COG0848	biopolymer transport protein
Patl_2988	COG0811	peptide transport
Patl_2989	COG0811	peptide transport
Patl_2996	COG1522	sequence-specific DNA binding
Patl_3000	COG3768	UPF0283 membrane protein
Patl_3001	COG3106	COG3106 Predicted ATPase
Patl_3004	COG1842	Phage shock protein A
Patl_3005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Patl_3006	COG0747	negative chemotaxis
Patl_3007	COG4168	peptide transport system, permease
Patl_3008	COG4171	peptide transport system, permease
Patl_3010	COG4172	Belongs to the ABC transporter superfamily
Patl_3011	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Patl_3012	COG0511	ligase activity, forming carbon-carbon bonds
Patl_3012	COG5016	pyruvate
Patl_3014	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Patl_3015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Patl_3021	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Patl_3023	COG0835	chemotaxis
Patl_3025	COG1192	Involved in chromosome partitioning
Patl_3026	COG2201	protein-glutamate methylesterase activity
Patl_3027	COG0643	Histidine kinase
Patl_3027	COG2198	Histidine kinase
Patl_3028	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Patl_3031	COG0455	bacterial-type flagellum organization
Patl_3033	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Patl_3034	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Patl_3036	COG1987	bacterial-type flagellum assembly
Patl_3046	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Patl_3049	COG2204	response regulator
Patl_3050	COG3852	Histidine kinase
Patl_3051	COG2204	response regulator
Patl_3059	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Patl_3061	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Patl_3063	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Patl_3065	COG1215	transferase activity, transferring glycosyl groups
Patl_3066	COG0463	Glycosyl transferase, family 2
Patl_3066	COG1216	Glycosyl transferase, family 2
Patl_3067	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Patl_3070	COG1215	transferase activity, transferring glycosyl groups
Patl_3071	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_3076	COG2089	acid synthase
Patl_3078	COG1083	cytidylyl-transferase
Patl_3079	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Patl_3080	COG1086	Polysaccharide biosynthesis protein
Patl_3083	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Patl_3084	COG1334	flagellar protein FlaG
Patl_3085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Patl_3090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Patl_3091	COG4786	Flagellar basal body rod
Patl_3091	COG1256	bacterial-type flagellum assembly
Patl_3092	COG3951	Flagellar rod assembly protein muramidase FlgJ
Patl_3092	COG1705	Flagellar rod assembly protein muramidase FlgJ
Patl_3093	COG1706	bacterial-type flagellum-dependent cell motility
Patl_3095	COG4786	Flagellar basal body rod
Patl_3096	COG4787	bacterial-type flagellum-dependent cell motility
Patl_3097	COG1749	Flagellar hook protein flgE
Patl_3098	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Patl_3099	COG1558	bacterial-type flagellum-dependent cell motility
Patl_3100	COG1815	bacterial-type flagellum-dependent cell motility
Patl_3101	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Patl_3102	COG0835	chemotaxis
Patl_3102	COG0784	Response regulator, receiver
Patl_3109	COG4772	TonB-dependent receptor
Patl_3113	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Patl_3113	COG0047	phosphoribosylformylglycinamidine synthase activity
Patl_3114	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Patl_3115	COG0590	tRNA wobble adenosine to inosine editing
Patl_3119	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Patl_3119	COG0519	Catalyzes the synthesis of GMP from XMP
Patl_3120	COG0517	IMP dehydrogenase activity
Patl_3120	COG0516	GMP reductase activity
Patl_3121	COG1570	exodeoxyribonuclease VII activity
Patl_3122	COG1160	GTP binding
Patl_3123	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Patl_3124	COG2976	Protein conserved in bacteria
Patl_3125	COG0124	histidyl-tRNA synthetase
Patl_3128	COG3063	Type IV pilus biogenesis stability protein PilW
Patl_3129	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Patl_3130	COG0105	UTP biosynthetic process
Patl_3132	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Patl_3133	COG0776	regulation of translation
Patl_3134	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Patl_3135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Patl_3136	COG0740	serine-type endopeptidase activity
Patl_3137	COG0544	peptidyl-prolyl cis-trans isomerase activity
Patl_3139	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Patl_3144	COG1131	(ABC) transporter
Patl_3146	COG0084	hydrolase, TatD family'
Patl_3147	COG0259	pyridoxamine-phosphate oxidase activity
Patl_3148	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Patl_3149	COG0571	ribonuclease III activity
Patl_3150	COG0681	Belongs to the peptidase S26 family
Patl_3151	COG0481	GTPase activity
Patl_3152	COG3086	response to oxidative stress
Patl_3155	COG1595	DNA-templated transcription, initiation
Patl_3156	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Patl_3159	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Patl_3160	COG0354	folic acid binding
Patl_3161	COG1047	Peptidyl-prolyl cis-trans
Patl_3163	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Patl_3175	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Patl_3176	COG1047	Peptidyl-prolyl cis-trans
Patl_3177	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Patl_3178	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Patl_3179	COG0196	riboflavin kinase activity
Patl_3180	COG0728	peptidoglycan biosynthetic process
Patl_3181	COG0268	Binds directly to 16S ribosomal RNA
Patl_3184	COG0564	pseudouridine synthase activity
Patl_3185	COG3098	single-species biofilm formation
Patl_3194	COG1611	Belongs to the LOG family
Patl_3197	COG0473	3-isopropylmalate dehydrogenase activity
Patl_3199	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Patl_3204	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Patl_3207	COG1216	Glycosyl transferase, family 2
Patl_3207	COG0438	transferase activity, transferring glycosyl groups
Patl_3211	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Patl_3216	COG0438	transferase activity, transferring glycosyl groups
Patl_3231	COG1459	type II secretion system
Patl_3232	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Patl_3236	COG1450	Type ii and iii secretion system protein
Patl_3244	COG3104	oligopeptide transport
Patl_3246	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Patl_3249	COG3088	subunit of a heme lyase
Patl_3249	COG4235	cytochrome complex assembly
Patl_3251	COG1138	Cytochrome C-type biogenesis protein
Patl_3252	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Patl_3253	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Patl_3254	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Patl_3255	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Patl_3256	COG4133	protoheme IX ABC transporter activity
Patl_3259	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Patl_3262	COG1546	Belongs to the CinA family
Patl_3263	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Patl_3264	COG0745	RESPONSE REGULATOR receiver
Patl_3265	COG0504	CTP synthase activity
Patl_3266	COG0148	phosphopyruvate hydratase activity
Patl_3268	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Patl_3269	COG0473	3-isopropylmalate dehydrogenase activity
Patl_3270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Patl_3271	COG0066	3-isopropylmalate dehydratase activity
Patl_3272	COG1609	Transcriptional regulator
Patl_3274	COG3459	Glycosyltransferase 36 associated
Patl_3275	COG2211	Major facilitator Superfamily
Patl_3281	COG3267	Type II secretory pathway component ExeA
Patl_3281	COG3409	Peptidoglycan-binding domain 1 protein
Patl_3282	COG0617	tRNA 3'-terminal CCA addition
Patl_3284	COG0513	Belongs to the DEAD box helicase family
Patl_3287	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Patl_3288	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Patl_3293	COG1346	cytolysis
Patl_3295	COG2204	response regulator
Patl_3296	COG0643	Histidine kinase
Patl_3296	COG2198	Histidine kinase
Patl_3298	COG2271	Major facilitator Superfamily
Patl_3303	COG0583	DNA-binding transcription factor activity
Patl_3304	COG2910	NAD(P)H-binding
Patl_3311	COG1595	DNA-templated transcription, initiation
Patl_3312	COG0583	DNA-binding transcription factor activity
Patl_3313	COG3746	phosphate-selective porin O and P
Patl_3315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Patl_3316	COG0581	inorganic phosphate transmembrane transporter activity
Patl_3317	COG0573	inorganic phosphate transmembrane transporter activity
Patl_3319	COG0306	phosphate transporter
Patl_3320	COG1392	Phosphate transport regulator
Patl_3322	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Patl_3323	COG0248	Ppx GppA phosphatase
Patl_3327	COG3588	fructose-bisphosphate aldolase
Patl_3328	COG0126	phosphoglycerate kinase activity
Patl_3329	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Patl_3331	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Patl_3332	COG0501	Belongs to the peptidase M48B family
Patl_3333	COG0668	transmembrane transport
Patl_3334	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Patl_3338	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Patl_3338	COG0678	peroxiredoxin activity
Patl_3340	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Patl_3341	COG0237	dephospho-CoA kinase activity
Patl_3342	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Patl_3343	COG1459	type II secretion system
Patl_3345	COG0157	Belongs to the NadC ModD family
Patl_3347	COG3023	N-Acetylmuramoyl-L-alanine amidase
Patl_3348	COG3725	Membrane protein required for beta-lactamase induction
Patl_3349	COG2186	Transcriptional regulator
Patl_3350	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Patl_3351	COG0508	dehydrogenase complex catalyzes the overall conversion of
Patl_3352	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Patl_3353	COG3590	peptidase
Patl_3354	COG3313	Fe-S protein
Patl_3360	COG5001	Diguanylate cyclase
Patl_3360	COG3300	MHYT domain
Patl_3364	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Patl_3367	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Patl_3373	COG5002	protein histidine kinase activity
Patl_3373	COG5001	Diguanylate cyclase
Patl_3378	COG3081	Nucleoid-associated protein
Patl_3379	COG3082	Protein of unknown function (DUF1414)
Patl_3380	COG3083	sulfuric ester hydrolase activity
Patl_3381	COG2226	methyltransferase
Patl_3383	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Patl_3384	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Patl_3384	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Patl_3387	COG3101	peptidyl-lysine hydroxylation
Patl_3394	COG2171	N-acyltransferase activity
Patl_3395	COG0798	PFAM Bile acid sodium symporter
Patl_3396	COG0431	NADPH-dependent FMN reductase
Patl_3398	COG0640	Transcriptional regulator
Patl_3415	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Patl_3416	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Patl_3418	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Patl_3419	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Patl_3420	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Patl_3421	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Patl_3425	COG0527	aspartate kinase activity
Patl_3430	COG0693	protein deglycase activity
Patl_3431	COG1032	radical SAM domain protein
Patl_3432	COG2951	lytic endotransglycosylase activity
Patl_3433	COG0242	peptide deformylase activity
Patl_3436	COG3240	lipase activity
Patl_3442	COG0420	3'-5' exonuclease activity
Patl_3443	COG0419	ATPase involved in DNA repair
Patl_3455	COG2814	Major facilitator Superfamily
Patl_3456	COG1061	Type III restriction enzyme res subunit
Patl_3458	COG2999	glutathione oxidoreductase activity
Patl_3459	COG0405	Gamma-glutamyltransferase
Patl_3465	COG1522	sequence-specific DNA binding
Patl_3469	COG1187	pseudouridine synthase activity
Patl_3470	COG0457	Tetratricopeptide repeat
Patl_3472	COG1017	nitric oxide dioxygenase activity
Patl_3472	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Patl_3475	COG3604	Transcriptional regulator
Patl_3476	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Patl_3478	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
Patl_3479	COG0515	serine threonine protein kinase
Patl_3480	COG2116	formate transmembrane transporter activity
Patl_3481	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Patl_3482	COG1162	GTPase activity
Patl_3483	COG0688	phosphatidylethanolamine metabolic process
Patl_3485	COG0584	glycerophosphoryl diester phosphodiesterase
Patl_3490	COG0312	modulator of DNA gyrase
Patl_3490	COG0312	modulator of DNA gyrase
Patl_3491	COG0312	modulator of DNA gyrase
Patl_3493	COG0714	Associated with various cellular activities
Patl_3498	COG2095	MarC family integral membrane protein
Patl_3500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Patl_3501	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Patl_3502	COG0006	proline dipeptidase activity
Patl_3503	COG3079	Belongs to the UPF0149 family
Patl_3505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Patl_3506	COG1957	nucleoside hydrolase
Patl_3507	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Patl_3508	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Patl_3510	COG0494	nUDIX hydrolase
Patl_3511	COG0653	protein targeting
Patl_3512	COG0739	heme binding
Patl_3513	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Patl_3514	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Patl_3515	COG0849	cell division
Patl_3516	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Patl_3517	COG1181	Belongs to the D-alanine--D-alanine ligase family
Patl_3518	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Patl_3519	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Patl_3520	COG0772	Belongs to the SEDS family
Patl_3522	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Patl_3523	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Patl_3525	COG0768	penicillin binding
Patl_3526	COG3116	cell division
Patl_3527	COG0275	rRNA processing
Patl_3528	COG2001	Belongs to the MraZ family
Patl_3529	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_3532	COG2186	Transcriptional regulator
Patl_3533	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Patl_3543	COG2205	protein histidine kinase activity
Patl_3543	COG5002	protein histidine kinase activity
Patl_3543	COG0784	Response regulator, receiver
Patl_3544	COG1404	Belongs to the peptidase S8 family
Patl_3546	COG4251	negative regulation of phosphorylation
Patl_3547	COG2201	protein-glutamate methylesterase activity
Patl_3548	COG2205	protein histidine kinase activity
Patl_3548	COG0784	Response regulator, receiver
Patl_3560	COG0795	lipopolysaccharide-transporting ATPase activity
Patl_3561	COG0795	lipopolysaccharide-transporting ATPase activity
Patl_3562	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Patl_3563	COG2927	DNA polymerase III (CHI subunit)
Patl_3564	COG0525	valine-tRNA ligase activity
Patl_3565	COG0737	Belongs to the 5'-nucleotidase family
Patl_3566	COG5001	Diguanylate cyclase
Patl_3566	COG4251	negative regulation of phosphorylation
Patl_3566	COG3706	GGDEF domain
Patl_3566	COG2203	Gaf domain
Patl_3571	COG0745	RESPONSE REGULATOR receiver
Patl_3573	COG0348	domain, Protein
Patl_3574	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Patl_3575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Patl_3576	COG3706	GGDEF domain
Patl_3577	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Patl_3581	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Patl_3591	COG0509	glycine decarboxylation via glycine cleavage system
Patl_3592	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Patl_3593	COG0583	DNA-binding transcription factor activity
Patl_3594	COG3267	Type II secretory pathway component ExeA
Patl_3594	COG3409	Peptidoglycan-binding domain 1 protein
Patl_3595	COG1272	protein, Hemolysin III
Patl_3597	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Patl_3600	COG2827	Endonuclease containing a URI domain
Patl_3603	COG1560	Kdo2-lipid A biosynthetic process
Patl_3604	COG0784	Response regulator, receiver
Patl_3604	COG2205	protein histidine kinase activity
Patl_3604	COG5002	protein histidine kinase activity
Patl_3607	COG4572	Cation transport regulator
Patl_3608	COG2354	Protein conserved in bacteria
Patl_3609	COG2861	carbohydrate metabolic process
Patl_3610	COG4942	peptidase
Patl_3611	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Patl_3612	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Patl_3613	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Patl_3614	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Patl_3615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Patl_3616	COG4682	membrane
Patl_3620	COG3022	response to hydroperoxide
Patl_3622	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Patl_3623	COG0166	Belongs to the GPI family
Patl_3628	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Patl_3629	COG0745	RESPONSE REGULATOR receiver
Patl_3630	COG0417	DNA replication proofreading
Patl_3631	COG0745	RESPONSE REGULATOR receiver
Patl_3631	COG3706	GGDEF domain
Patl_3634	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Patl_3641	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_3643	COG1914	H( )-stimulated, divalent metal cation uptake system
Patl_3644	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Patl_3649	COG0246	Mannitol dehydrogenase
Patl_3654	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Patl_3655	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Patl_3656	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Patl_3657	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Patl_3658	COG2271	Major facilitator Superfamily
Patl_3660	COG2186	Transcriptional regulator
Patl_3661	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_3662	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Patl_3663	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Patl_3665	COG0598	Magnesium transport protein CorA
Patl_3666	COG0189	ligase activity
Patl_3667	COG0189	ligase activity
Patl_3667	COG4067	protein conserved in archaea
Patl_3669	COG3706	GGDEF domain
Patl_3669	COG4251	negative regulation of phosphorylation
Patl_3669	COG5001	Diguanylate cyclase
Patl_3669	COG2203	Gaf domain
Patl_3670	COG1309	transcriptional regulator
Patl_3671	COG0668	transmembrane transport
Patl_3672	COG1979	alcohol dehydrogenase
Patl_3673	COG2207	Transcriptional regulator
Patl_3674	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Patl_3676	COG0463	Glycosyl transferase, family 2
Patl_3677	COG0745	RESPONSE REGULATOR receiver
Patl_3680	COG0625	glutathione transferase activity
Patl_3682	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Patl_3683	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Patl_3692	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Patl_3693	COG3107	peptidoglycan biosynthetic process
Patl_3694	COG0792	nuclease activity
Patl_3695	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Patl_3696	COG2823	Periplasmic or secreted lipoprotein
Patl_3697	COG2969	positive regulation of protein catabolic process
Patl_3698	COG0625	glutathione transferase activity
Patl_3699	COG2857	Cytochrome c1
Patl_3700	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Patl_3701	COG0723	plastoquinol--plastocyanin reductase activity
Patl_3702	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Patl_3703	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Patl_3706	COG3956	TIGRFAM MazG family protein
Patl_3707	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Patl_3708	COG0736	holo-[acyl-carrier-protein] synthase activity
Patl_3709	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Patl_3710	COG1381	Involved in DNA repair and RecF pathway recombination
Patl_3712	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Patl_3713	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Patl_3719	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Patl_3720	COG0762	integral membrane protein
Patl_3723	COG3850	Histidine kinase
Patl_3723	COG3437	response regulator, receiver
Patl_3723	COG2205	protein histidine kinase activity
Patl_3723	COG4999	Histidine kinase
Patl_3724	COG2207	Transcriptional regulator
Patl_3724	COG1609	Transcriptional regulator
Patl_3725	COG1070	Carbohydrate kinase
Patl_3726	COG2115	Belongs to the xylose isomerase family
Patl_3727	COG0477	Major facilitator Superfamily
Patl_3732	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Patl_3733	COG1278	Cold shock
Patl_3734	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Patl_3736	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Patl_3737	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Patl_3738	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Patl_3739	COG0142	geranyltranstransferase activity
Patl_3744	COG0359	binds to the 23S rRNA
Patl_3745	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Patl_3747	COG0784	Response regulator, receiver
Patl_3747	COG2198	Histidine kinase
Patl_3747	COG5002	protein histidine kinase activity
Patl_3748	COG0070	glutamate synthase
Patl_3748	COG0069	glutamate synthase activity
Patl_3748	COG0067	glutamate synthase
Patl_3749	COG0493	'glutamate synthase
Patl_3750	COG1454	alcohol dehydrogenase
Patl_3752	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Patl_3753	COG0459	protein refolding
Patl_3759	COG0604	alcohol dehydrogenase
Patl_3765	COG3093	addiction module antidote protein HigA
Patl_3769	COG3710	Transcriptional regulator
Patl_3778	COG2207	Transcriptional regulator
Patl_3783	COG1960	acyl-CoA dehydrogenase activity
Patl_3784	COG1278	Cold shock
Patl_3785	COG0557	exoribonuclease II activity
Patl_3795	COG4771	TonB-dependent receptor
Patl_3797	COG5001	Diguanylate cyclase
Patl_3797	COG3300	MHYT domain
Patl_3798	COG1538	Outer membrane efflux protein
Patl_3799	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Patl_3800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Patl_3810	COG2267	carboxylic ester hydrolase activity
Patl_3812	COG1024	Enoyl-CoA hydratase
Patl_3815	COG1914	H( )-stimulated, divalent metal cation uptake system
Patl_3819	COG2814	Major facilitator Superfamily
Patl_3821	COG1609	Transcriptional regulator
Patl_3822	COG0477	Major facilitator Superfamily
Patl_3823	COG1621	beta-fructofuranosidase activity
Patl_3824	COG0625	glutathione transferase activity
Patl_3829	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Patl_3830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Patl_3834	COG2814	Major facilitator Superfamily
Patl_3835	COG3706	GGDEF domain
Patl_3837	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Patl_3839	COG2067	long-chain fatty acid transport protein
Patl_3841	COG0783	Belongs to the Dps family
Patl_3843	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Patl_3844	COG0730	response to heat
Patl_3846	COG0494	nUDIX hydrolase
Patl_3849	COG1012	belongs to the aldehyde dehydrogenase family
Patl_3851	COG3025	triphosphatase activity
Patl_3852	COG4991	sh3 domain protein
Patl_3856	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Patl_3857	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Patl_3858	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Patl_3859	COG0585	pseudouridine synthase activity
Patl_3860	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Patl_3861	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Patl_3863	COG1388	LysM domain
Patl_3863	COG4942	peptidase
Patl_3864	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Patl_3867	COG0653	protein targeting
Patl_3868	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Patl_3869	COG0590	tRNA wobble adenosine to inosine editing
Patl_3871	COG1476	TRANSCRIPTIONal
Patl_3872	COG3153	acetyltransferase
Patl_3872	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Patl_3873	COG1166	arginine decarboxylase activity
Patl_3876	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Patl_3877	COG0697	spore germination
Patl_3878	COG2199	diguanylate cyclase activity
Patl_3878	COG2203	Gaf domain
Patl_3879	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Patl_3880	COG1349	DNA-binding transcription factor activity
Patl_3881	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Patl_3883	COG0667	Aldo Keto reductase
Patl_3888	COG2159	amidohydrolase
Patl_3889	COG2828	Protein conserved in bacteria
Patl_3890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Patl_3891	COG0583	DNA-binding transcription factor activity
Patl_3897	COG0583	DNA-binding transcription factor activity
Patl_3904	COG4771	TonB-dependent receptor
Patl_3905	COG1309	transcriptional regulator
Patl_3912	COG1960	acyl-CoA dehydrogenase activity
Patl_3914	COG5002	protein histidine kinase activity
Patl_3914	COG5001	Diguanylate cyclase
Patl_3915	COG0784	Response regulator, receiver
Patl_3915	COG2205	protein histidine kinase activity
Patl_3915	COG5002	protein histidine kinase activity
Patl_3916	COG0583	DNA-binding transcription factor activity
Patl_3918	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
Patl_3919	COG2205	protein histidine kinase activity
Patl_3920	COG0745	RESPONSE REGULATOR receiver
Patl_3922	COG2304	oxidoreductase activity
Patl_3926	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Patl_3927	COG1131	(ABC) transporter
Patl_3928	COG0842	Transport permease protein
Patl_3929	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Patl_3931	COG0076	glutamate decarboxylase activity
Patl_3932	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Patl_3933	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Patl_3935	COG0617	tRNA 3'-terminal CCA addition
Patl_3937	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Patl_3938	COG1489	DNA binding
Patl_3941	COG2095	MarC family integral membrane protein
Patl_3943	COG0742	ribosomal rna small subunit methyltransferase
Patl_3944	COG0552	protein localization to endoplasmic reticulum
Patl_3945	COG2884	Cell division ATP-binding protein ftsE
Patl_3946	COG2177	Part of the ABC transporter FtsEX involved in
Patl_3947	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Patl_3949	COG0456	acetyltransferase
Patl_3950	COG1490	D-aminoacyl-tRNA deacylase activity
Patl_3954	COG1295	ribonuclease BN
Patl_3955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Patl_3957	COG0625	glutathione transferase activity
Patl_3959	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Patl_3960	COG5002	protein histidine kinase activity
Patl_3960	COG5001	Diguanylate cyclase
Patl_3961	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
Patl_3961	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Patl_3962	COG3064	Membrane
Patl_3964	COG2957	Belongs to the agmatine deiminase family
Patl_3970	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Patl_3973	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Patl_3973	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Patl_3974	COG0802	atpase or kinase
Patl_3977	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Patl_3978	COG1923	regulation of RNA biosynthetic process
Patl_3979	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Patl_3980	COG0330	HflC and HflK could
Patl_3981	COG0330	HflC and HflK could
Patl_3983	COG0625	glutathione transferase activity
Patl_3985	COG1653	transport
Patl_3987	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Patl_3988	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Patl_3990	COG2885	chlorophyll binding
Patl_3990	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Patl_3993	COG1960	acyl-CoA dehydrogenase activity
Patl_3994	COG0667	Aldo Keto reductase
Patl_3996	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Patl_3997	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Patl_3998	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Patl_3998	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Patl_3999	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Patl_4003	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Patl_4005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Patl_4006	COG0438	transferase activity, transferring glycosyl groups
Patl_4007	COG0438	transferase activity, transferring glycosyl groups
Patl_4013	COG0288	reversible hydration of carbon dioxide
Patl_4014	COG0583	DNA-binding transcription factor activity
Patl_4016	COG1448	Aminotransferase
Patl_4019	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Patl_4021	COG0626	cystathionine gamma-synthase activity
Patl_4022	COG1765	OsmC-like protein
Patl_4025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Patl_4026	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Patl_4027	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Patl_4030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Patl_4034	COG1573	uracil-dna glycosylase
Patl_4035	COG5001	Diguanylate cyclase
Patl_4035	COG3300	MHYT domain
Patl_4038	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Patl_4039	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Patl_4044	COG1842	Phage shock protein A
Patl_4046	COG1028	Short-chain dehydrogenase reductase Sdr
Patl_4051	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Patl_4055	COG0204	Acyl-transferase
Patl_4056	COG0204	Acyl-transferase
Patl_4057	COG0668	transmembrane transport
Patl_4059	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Patl_4060	COG0733	neurotransmitter:sodium symporter activity
Patl_4063	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Patl_4067	COG0716	FMN binding
Patl_4069	COG0848	biopolymer transport protein
Patl_4070	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Patl_4073	COG0019	diaminopimelate decarboxylase activity
Patl_4074	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Patl_4077	COG1011	Hydrolase
Patl_4078	COG1045	serine acetyltransferase
Patl_4080	COG3706	GGDEF domain
Patl_4080	COG0745	RESPONSE REGULATOR receiver
Patl_4081	COG2962	Rard protein
Patl_4088	COG1803	Methylglyoxal synthase
Patl_4088	COG1597	lipid kinase activity
Patl_4090	COG0668	transmembrane transport
Patl_4094	COG3706	GGDEF domain
Patl_4096	COG0270	DNA (cytosine-5-)-methyltransferase activity
Patl_4102	COG1074	ATP-dependent DNA helicase activity
Patl_4114	COG5001	Diguanylate cyclase
Patl_4114	COG5002	protein histidine kinase activity
Patl_4122	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Patl_4123	COG1309	transcriptional regulator
Patl_4128	COG0625	glutathione transferase activity
Patl_4134	COG0656	L-ascorbic acid biosynthetic process
Patl_4135	COG4325	translation initiation factor activity
Patl_4141	COG1295	ribonuclease BN
Patl_4144	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Patl_4145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Patl_4147	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Patl_4150	COG2853	Lipoprotein
Patl_4153	COG0784	Response regulator, receiver
Patl_4154	COG4251	negative regulation of phosphorylation
Patl_4156	COG2204	response regulator
Patl_4157	COG0454	-acetyltransferase
Patl_4157	COG0456	acetyltransferase
Patl_4160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Patl_4164	COG1737	Transcriptional regulator
Patl_4167	COG3876	Protein conserved in bacteria
Patl_4168	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Patl_4174	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Patl_4176	COG1619	proteins homologs of microcin C7 resistance protein MccF
Patl_4177	COG5001	Diguanylate cyclase
Patl_4177	COG2203	Gaf domain
Patl_4177	COG3706	GGDEF domain
Patl_4177	COG4251	negative regulation of phosphorylation
Patl_4178	COG3177	Filamentation induced by cAMP protein fic
Patl_4180	COG0488	(ABC) transporter
Patl_4181	COG0840	transmembrane signaling receptor activity
Patl_4187	COG0281	malic enzyme
Patl_4188	COG0254	rRNA binding
Patl_4189	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Patl_4190	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Patl_4191	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Patl_4192	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Patl_4197	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Patl_4203	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Patl_4204	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Patl_4206	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Patl_4207	COG0339	signal peptide processing
Patl_4214	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Patl_4215	COG0805	protein transport
Patl_4217	COG0084	hydrolase, TatD family'
Patl_4218	COG0745	RESPONSE REGULATOR receiver
Patl_4218	COG3706	GGDEF domain
Patl_4220	COG0248	Ppx GppA phosphatase
Patl_4221	COG0513	Belongs to the DEAD box helicase family
Patl_4222	COG3118	belongs to the thioredoxin family
Patl_4223	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Patl_4225	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Patl_4226	COG2183	response to ionizing radiation
Patl_4230	COG0596	Alpha beta hydrolase
Patl_4231	COG1040	competence protein
Patl_4233	COG0316	Belongs to the HesB IscA family
Patl_4233	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Patl_4234	COG0534	Mate efflux family protein
Patl_4235	COG1649	PFAM Uncharacterised BCR, COG1649
Patl_4235	COG0726	polysaccharide deacetylase
Patl_4237	COG1999	signal sequence binding
Patl_4238	COG0109	protoheme IX farnesyltransferase activity
Patl_4239	COG1612	heme a metabolic process
Patl_4244	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Patl_4245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Patl_4246	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Patl_4247	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Patl_4248	COG2937	Belongs to the GPAT DAPAT family
Patl_4249	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Patl_4250	COG0129	dihydroxy-acid dehydratase activity
Patl_4252	COG0606	chelatase, subunit chli
Patl_4254	COG0583	DNA-binding transcription factor activity
Patl_4255	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Patl_4258	COG2814	Major facilitator Superfamily
Patl_4260	COG0288	reversible hydration of carbon dioxide
Patl_4262	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Patl_4266	COG1252	NADH dehydrogenase
Patl_4268	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Patl_4269	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Patl_4272	COG0628	permease
Patl_4277	COG1228	amidohydrolase
Patl_4280	COG0425	Belongs to the sulfur carrier protein TusA family
Patl_4281	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Patl_4282	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Patl_4283	COG1561	YicC-like family, N-terminal region
Patl_4285	COG2199	diguanylate cyclase activity
Patl_4285	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Patl_4293	COG5002	protein histidine kinase activity
Patl_4293	COG0784	Response regulator, receiver
Patl_4293	COG2198	Histidine kinase
Patl_4294	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Patl_4295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Patl_4296	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Patl_4297	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Patl_4298	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Patl_4299	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Patl_4301	COG0356	it plays a direct role in the translocation of protons across the membrane
Patl_4302	COG3312	ion transport
Patl_4303	COG1475	DNA binding
Patl_4304	COG1192	Involved in chromosome partitioning
Patl_4305	COG0357	Ribosomal RNA small subunit methyltransferase G
Patl_4306	COG0445	tRNA wobble uridine modification
Patl_4309	COG0716	FMN binding
Patl_4310	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Patl_4311	COG1666	GTP binding
Patl_4312	COG0706	membrane insertase activity
Patl_4313	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Patl_4314	COG0594	ribonuclease P activity
Patl_4315	COG0230	Belongs to the bacterial ribosomal protein bL34 family