locus-tag	class	description
D172_000015	ENOG4108Z0R	Transferase
D172_000020	ENOG4105SG3	Protein of unknown function (DUF1488)
D172_000025	ENOG4105E2X	shikimate dehydrogenase
D172_000030	ENOG4108Z18	K06886 hemoglobin
D172_000035	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
D172_000040	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D172_000045	ENOG4108WI1	Dna topoisomerase
D172_000050	ENOG4108RPN	Protein smg homolog
D172_000055	ENOG4105C79	DNA protecting protein DprA
D172_000065	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
D172_000070	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
D172_000075	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
D172_000080	ENOG4105C1A	potassium transporter peripheral membrane
D172_000105	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D172_000110	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
D172_000115	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
D172_000120	ENOG4107SC1	transglycosylase
D172_000125	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D172_000130	ENOG4105CHU	acetyl-coa acetyltransferase
D172_000135	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
D172_000150	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
D172_000155	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
D172_000160	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D172_000165	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
D172_000170	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
D172_000175	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
D172_000180	ENOG4105VG0	50S ribosomal protein l34
D172_000185	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
D172_000190	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
D172_000195	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
D172_000200	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D172_000205	ENOG4105QTB	Flavodoxin
D172_000210	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
D172_000215	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
D172_000220	ENOG4107QJE	Chromosome Partitioning Protein
D172_000225	ENOG4105FA0	parb-like partition protein
D172_000230	ENOG41064MJ	ATP synthase, subunit I
D172_000235	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
D172_000240	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D172_000245	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D172_000250	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D172_000255	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
D172_000260	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
D172_000265	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
D172_000270	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
D172_000275	ENOG4108M3R	transcriptional activator CadC
D172_000280	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D172_000295	ENOG4108J1Q	
D172_000350	ENOG4108UK5	Transposase
D172_000355	ENOG4105BZU	Histidine kinase
D172_000360	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D172_000365	ENOG4105CW7	secretion protein, HlyD family
D172_000370	ENOG4105C19	ABC transporter
D172_000375	ENOG4107RBB	ABC transporter, permease
D172_000405	ENOG4108UW5	maltose o-acetyltransferase
D172_000410	ENOG410804X	Transcriptional regulator
D172_000415	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
D172_000425	ENOG4105C1J	atp-dependent rna helicase
D172_000435	ENOG4107ENK	receptor
D172_000450	ENOG4105VEQ	Cold shock protein
D172_000455	ENOG4105VEQ	Cold shock protein
D172_000490	ENOG4105E08	Glycoside hydrolase, family 9
D172_000500	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D172_000520	ENOG4105WD1	Membrane
D172_000535	ENOG4105DSB	aldose 1-epimerase
D172_000545	ENOG4105CKV	Membrane
D172_000565	ENOG4105JAB	phenazine biosynthesis protein, phzf family
D172_000595	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
D172_000600	ENOG4105CUG	Oligopeptidase b
D172_000605	ENOG4105BZU	Histidine kinase
D172_000610	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D172_000630	ENOG4105W39	Membrane
D172_000635	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
D172_000640	ENOG4105EUJ	GTP cyclohydrolase i
D172_000645	ENOG410642E	Short chain dehydrogenase
D172_000650	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
D172_000655	ENOG4108YXG	UPF0502 protein
D172_000660	ENOG4105BZU	Histidine kinase
D172_000665	ENOG4105DDY	UPF0142 protein ycaO
D172_000675	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
D172_000680	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
D172_000685	ENOG4105KPY	Small multidrug resistance protein
D172_000710	ENOG4105FE9	pseudouridine synthase
D172_000735	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
D172_000740	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D172_000750	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
D172_000755	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D172_000765	ENOG4105XQ6	frataxin-like protein
D172_000770	ENOG4106CJB	Phospholipase Carboxylesterase
D172_000780	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
D172_000785	ENOG4105ECF	c-methyltransferase
D172_000795	ENOG4105BZU	Histidine kinase
D172_000800	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
D172_000810	ENOG4107QK7	reductase
D172_000815	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
D172_000820	ENOG4108NVR	Methyl-accepting chemotaxis
D172_000830	ENOG4105CKW	Inner membrane protein yedI
D172_000845	ENOG4105E0K	tonB-dependent siderophore receptor
D172_000850	ENOG4105C1J	atp-dependent rna helicase
D172_000860	ENOG4105BZU	Histidine kinase
D172_000870	ENOG4105K63	Thioredoxin
D172_000875	ENOG4105C1J	atp-dependent rna helicase
D172_000880	ENOG4105C9X	ppx gppa phosphatase
D172_000905	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
D172_000910	ENOG4105C4R	Atp-dependent dna helicase
D172_000920	ENOG4105XTV	UPF0231 protein
D172_000925	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
D172_000940	ENOG4105DHP	deoxycytidine triphosphate deaminase
D172_000945	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
D172_000950	ENOG4107RK2	ADP-ribose diphosphatase NudE
D172_000955	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
D172_000975	ENOG4105EN6	Membrane
D172_000980	ENOG4105C0P	Mg chelatase subunit ChlI
D172_000985	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D172_001000	ENOG4105BZU	Histidine kinase
D172_001010	ENOG4107R88	Chemotaxis protein (CheV)
D172_001025	ENOG4105C29	acyl-CoA thioesterase
D172_001030	ENOG4105E55	glycerol-3-phosphate acyltransferase
D172_001040	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
D172_001045	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
D172_001050	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
D172_001055	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D172_001060	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
D172_001065	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
D172_001070	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
D172_001075	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
D172_001080	ENOG41083MP	50s ribosomal protein l29
D172_001085	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
D172_001095	ENOG4108K8S	endonuclease I
D172_001100	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
D172_001105	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
D172_001110	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
D172_001120	ENOG4107QM5	aconitate hydratase
D172_001145	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D172_001150	ENOG4105CUX	Signal transduction histidine kinase
D172_001160	ENOG4105C5F	glutamine synthetase
D172_001195	ENOG4107S2Z	UPF0761 membrane protein
D172_001200	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
D172_001210	ENOG4105SUU	thioesterase domain
D172_001215	ENOG4105HDD	phospholipase
D172_001225	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D172_001235	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D172_001245	ENOG4105CNG	UPF0061 protein
D172_001250	ENOG4105KCK	Peptidoglycan-associated lipoprotein
D172_001265	ENOG4107RZZ	dna polymerase iii epsilon subunit
D172_001270	ENOG4107QIJ	Aconitate hydratase 2
D172_001280	ENOG4105C9B	Cysteine desulfurase
D172_001315	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D172_001335	ENOG4107RUZ	Sss sodium solute transporter superfamily
D172_001345	ENOG4107EJG	GntR family transcriptional regulator
D172_001350	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
D172_001355	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
D172_001360	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
D172_001365	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
D172_001375	ENOG4105EE0	oxidoreductase
D172_001380	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
D172_001385	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
D172_001390	ENOG4105CMR	udp-glucose 4-epimerase
D172_001395	ENOG4105UBK	short-chain dehydrogenase reductase
D172_001405	ENOG4105DDQ	anthranilate synthase
D172_001415	ENOG4105C8Y	Acetylornithine aminotransferase
D172_001425	ENOG4105C26	Dehydrogenase
D172_001435	ENOG4108UKZ	OsmC family
D172_001440	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
D172_001450	ENOG4105C44	Serine transporter
D172_001455	ENOG4105BZS	acriflavin resistance protein
D172_001460	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
D172_001465	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
D172_001470	ENOG4105C0W	non-ribosomal peptide synthetase
D172_001475	ENOG4108ZT1	Transcriptional regulator
D172_001480	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D172_001485	ENOG4108KTG	Membrane protein, drug metabolite transporter
D172_001490	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
D172_001495	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
D172_001505	ENOG4108MUZ	hydrolase
D172_001520	ENOG4105PBD	transposase, IS3 IS911 family protein
D172_001535	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
D172_001540	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
D172_001550	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
D172_001555	ENOG4105C11	sulfate adenylyltransferase), subunit 2
D172_001560	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D172_001565	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
D172_001590	ENOG4105PM1	preprotein translocase subunit SecE
D172_001595	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
D172_001600	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
D172_001605	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
D172_001610	ENOG4108VZM	50s ribosomal protein L10
D172_001615	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
D172_001620	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D172_001625	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D172_001630	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
D172_001635	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
D172_001640	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D172_001645	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D172_001650	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
D172_001655	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
D172_001670	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D172_001675	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
D172_001680	ENOG4105FS0	cytoplasmic membrane protein
D172_001685	ENOG4105VF7	tolerance protein
D172_001690	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
D172_001695	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
D172_001700	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
D172_001705	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D172_001710	ENOG4105K8N	protein family UPF0079, ATPase
D172_001715	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
D172_001720	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
D172_001725	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
D172_001730	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
D172_001735	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
D172_001740	ENOG4107QJR	hflk protein
D172_001745	ENOG4105EPW	hflc protein
D172_001750	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D172_001755	ENOG4108UV7	flagellar protein motX
D172_001770	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
D172_001775	ENOG4105BZU	Histidine kinase
D172_001780	ENOG4105BZU	Histidine kinase
D172_001815	ENOG41090Y2	cytochrome C
D172_001820	ENOG4105MP9	class II Aldolase
D172_001825	ENOG4105CXK	mandelate racemase muconate lactonizing
D172_001860	ENOG4105CHR	reductase
D172_001865	ENOG4108YZY	peptidylprolyl cis-trans isomerase
D172_001870	ENOG4105E9H	Lytic Murein transglycosylase
D172_001885	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
D172_001890	ENOG4105D6S	protein involved in catabolism of external DNA
D172_001895	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
D172_001900	ENOG4105D58	Diguanylate phosphodiesterase
D172_001925	ENOG4108IJF	Heavy metal efflux pump, CzcA
D172_001935	ENOG4105C9X	ppx gppa phosphatase
D172_001940	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
D172_001950	ENOG4105C8U	phosphate abc transporter
D172_001955	ENOG4105C8U	phosphate abc transporter
D172_001960	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D172_001970	ENOG4107IX6	phosphate transport regulator
D172_001975	ENOG4105CJ3	phosphate transporter
D172_001980	ENOG4105C5Q	Transcriptional regulator
D172_001990	ENOG4105BZU	Histidine kinase
D172_001995	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
D172_002000	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
D172_002005	ENOG4105VIE	preprotein translocase, subunit YajC
D172_002010	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D172_002015	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D172_002020	ENOG4105BZU	Histidine kinase
D172_002030	ENOG4105ECY	inositol monophosphatase
D172_002045	ENOG4105K3G	Periplasmic Protein
D172_002080	ENOG4105BZU	Histidine kinase
D172_002135	ENOG4105C12	Phosphoribosylglycinamide synthetase
D172_002145	ENOG4105DC1	bifunctional purine biosynthesis protein purh
D172_002150	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
D172_002155	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D172_002160	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D172_002165	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D172_002170	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
D172_002185	ENOG4106H78	methyltransferase
D172_002190	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
D172_002195	ENOG4105CAK	Cell division ATP-binding protein ftsE
D172_002200	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
D172_002205	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D172_002215	ENOG4105CN1	protease
D172_002220	ENOG41063SB	peptidase
D172_002225	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D172_002230	ENOG4107YZP	Rhodanese domain protein
D172_002240	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
D172_002245	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
D172_002250	ENOG4105C8Q	Methyl-accepting chemotaxis
D172_002265	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
D172_002275	ENOG4108EUD	Lysophospholipase
D172_002280	ENOG4105E0F	Histidine kinase
D172_002285	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D172_002295	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
D172_002300	ENOG4107QHF	type ii secretion system protein e
D172_002305	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
D172_002310	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
D172_002330	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
D172_002340	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
D172_002345	ENOG41073TP	transcriptional regulator
D172_002350	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
D172_002355	ENOG4107QSN	dihydrolipoamide acetyltransferase
D172_002360	ENOG4107QN2	dihydrolipoyl dehydrogenase
D172_002365	ENOG4106IUH	DTW domain containing protein
D172_002385	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D172_002395	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
D172_002400	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
D172_002405	ENOG4105EAH	synthase
D172_002410	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
D172_002415	ENOG4105K46	50S ribosomal protein l27
D172_002420	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D172_002435	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
D172_002445	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
D172_002450	ENOG4105W5Q	DNA repair protein (RadC
D172_002455	ENOG4105KDC	50s ribosomal protein l28
D172_002460	ENOG4105W0E	50S ribosomal protein L33
D172_002465	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D172_002470	ENOG4105CBX	hi0933 family
D172_002475	ENOG4108R6W	Transcriptional regulator, ARAC family
D172_002480	ENOG4108RNG	Permease of the drug metabolite transporter
D172_002495	ENOG4105D7K	pfkb domain protein
D172_002525	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
D172_002535	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
D172_002540	ENOG4108NVR	Methyl-accepting chemotaxis
D172_002555	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D172_002560	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
D172_002565	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
D172_002570	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
D172_002575	ENOG4105EHM	Aminoglycoside phosphotransferase
D172_002580	ENOG4108S0S	Nucleotidyl transferase
D172_002585	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
D172_002595	ENOG4105D3G	Pseudouridine synthase
D172_002600	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
D172_002605	ENOG4108IAB	Phoh family
D172_002610	ENOG4105BZU	Histidine kinase
D172_002615	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D172_002625	ENOG4105C5I	Dehydrogenase
D172_002635	ENOG4105XZD	Fe-S protein
D172_002650	ENOG4105BZU	Histidine kinase
D172_002655	ENOG4105EYW	Ion transport protein
D172_002660	ENOG4105CD5	CoA-binding domain protein
D172_002680	ENOG4105CSA	Coproporphyrinogen iii oxidase
D172_002685	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D172_002695	ENOG4108VIA	integral membrane protein
D172_002700	ENOG4105II7	pyrroline-5-carboxylate reductase
D172_002705	ENOG4105DFA	alanine racemase domain protein
D172_002710	ENOG4105CZX	twitching motility protein
D172_002715	ENOG4105CZX	twitching motility protein
D172_002720	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
D172_002725	ENOG4108UJU	UPF0301 protein
D172_002730	ENOG4105D7Z	glutathione synthase
D172_002735	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
D172_002750	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
D172_002760	ENOG4105D1S	lipid A biosynthesis
D172_002765	ENOG4105DFG	type I secretion outer membrane protein
D172_002770	ENOG41087AY	ADP-Ribose pyrophosphatase
D172_002775	ENOG4108SX3	cytoplasmic protein
D172_002780	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
D172_002785	ENOG4105IPS	esterase
D172_002790	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D172_002795	ENOG4105DKB	L-sorbosone dehydrogenase
D172_002800	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D172_002805	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
D172_002810	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
D172_002825	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D172_002830	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D172_002855	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D172_002860	ENOG4108VUY	thioesterase Superfamily protein
D172_002865	ENOG4105FR1	rard protein
D172_002870	ENOG4105BZU	Histidine kinase
D172_002875	ENOG4108WFC	UPF0438 protein yifE
D172_002880	ENOG4105CVI	Transcriptional regulator
D172_002890	ENOG4105E0A	ABC, transporter
D172_002895	ENOG4105EHG	Permease protein
D172_002900	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
D172_002905	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
D172_002910	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
D172_002915	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
D172_002930	ENOG4105D1Q	UPF0246 protein
D172_002935	ENOG4105D8X	mechanosensitive ion channel
D172_002950	ENOG4105C1J	atp-dependent rna helicase
D172_002955	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
D172_002960	ENOG4105E54	alpha-amylase
D172_002970	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
D172_002975	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D172_002980	ENOG4105T95	Thiol disulfide interChange protein
D172_002985	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
D172_002990	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
D172_002995	ENOG4105CRK	lysyL-tRNA synthetase
D172_003030	ENOG4105EHZ	conserved protein UCP016719
D172_003040	ENOG4107S6Z	Na H antiporter
D172_003100	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
D172_003105	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
D172_003110	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
D172_003115	ENOG4107RBR	Receptor
D172_003130	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
D172_003145	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
D172_003150	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
D172_003155	ENOG4105D06	uba thif-type nad fad binding protein
D172_003160	ENOG4105DJ4	phosphatidylserine decarboxylase
D172_003170	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
D172_003190	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
D172_003200	ENOG4105MYN	Zinc uptake regulation protein
D172_003205	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
D172_003255	ENOG4108TSE	Transferase
D172_003290	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D172_003300	ENOG410624X	efflux transporter, rnd family, mfp subunit
D172_003305	ENOG4105C19	ABC transporter
D172_003310	ENOG4107RBB	ABC transporter, permease
D172_003330	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D172_003335	ENOG41087YS	Phage shock protein A
D172_003375	ENOG4105BZU	Histidine kinase
D172_003380	ENOG4105CCT	upf0313 protein
D172_003385	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D172_003390	ENOG4105CJW	magnesium transporter
D172_003395	ENOG41080Z8	PHOSPHOCARRIER protein
D172_003400	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
D172_003405	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
D172_003410	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
D172_003415	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D172_003420	ENOG4108IUZ	ABC transporter
D172_003435	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
D172_003440	ENOG4105C2X	Arabinose 5-phosphate isomerase
D172_003450	ENOG4105DHJ	ABC, transporter
D172_003455	ENOG4105CY3	ABC transporter, permease
D172_003460	ENOG4107PE3	Mammalian cell entry related domain protein
D172_003465	ENOG4105E3I	toluene tolerance
D172_003470	ENOG4105UE2	Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane
D172_003475	ENOG4105VFK	BolA family
D172_003480	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
D172_003490	ENOG4105C0H	protease
D172_003500	ENOG4105D6Z	AFG1 family ATPase
D172_003505	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
D172_003510	ENOG4108UJD	30S ribosomal protein S9
D172_003515	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D172_003520	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D172_003525	ENOG4105EIX	cytochrome c1
D172_003530	ENOG4107MKT	Stringent starvation protein a
D172_003535	ENOG4105KB2	stringent starvation protein b
D172_003540	ENOG4105W4M	Transport-associated protein
D172_003545	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
D172_003550	ENOG41082RQ	UPF0102 protein
D172_003555	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
D172_003560	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
D172_003580	ENOG4108J1Q	
D172_003600	ENOG4107QSA	Oxaloacetate decarboxylase
D172_003605	ENOG4105D9Q	decarboxylase (Beta subunit)
D172_003610	ENOG4107QM2	Aldo Keto reductase
D172_003620	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D172_003630	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
D172_003640	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
D172_003645	ENOG4105BZU	Histidine kinase
D172_003650	ENOG41065U4	response regulator
D172_003655	ENOG4105BZU	Histidine kinase
D172_003660	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
D172_003665	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D172_003675	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
D172_003680	ENOG4105BZU	Histidine kinase
D172_003720	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
D172_003725	ENOG4105BZS	acriflavin resistance protein
D172_003735	ENOG4107RAQ	aminopeptidase
D172_003740	ENOG4105D0A	hydroxylase
D172_003745	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
D172_003755	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
D172_003760	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D172_003770	ENOG4105DUM	transcriptional regulator, lysR family
D172_003780	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
D172_003785	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
D172_003790	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D172_003860	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
D172_003870	ENOG4105N1F	Hnh endonuclease
D172_003880	ENOG4107Y60	(LipO)protein
D172_003890	ENOG4106B0W	Curli production assembly transport component CsgG
D172_003900	ENOG4108K3A	Glutathione S-transferase
D172_003910	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
D172_003915	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
D172_003920	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
D172_003925	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
D172_003930	ENOG4108AEY	RNA polymerase sigma factor
D172_003945	ENOG4105CDU	Replicative dna helicase
D172_003950	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D172_003985	ENOG4105CPI	Metal Dependent Phosphohydrolase
D172_003995	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
D172_004000	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
D172_004005	ENOG4105MYG	DNA polymerase iii, chi subunit
D172_004010	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D172_004015	ENOG4108M8S	permease YjgP YjgQ family protein
D172_004020	ENOG4108K5H	permease YjgP YjgQ family protein
D172_004060	ENOG4105DJ2	Major Facilitator Superfamily
D172_004065	ENOG4105R1U	AraC Family Transcriptional Regulator
D172_004070	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D172_004115	ENOG4105EA8	2-Nitropropane dioxygenase
D172_004125	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D172_004150	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
D172_004155	ENOG4105CPC	Aldo Keto reductase
D172_004165	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D172_004170	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D172_004175	ENOG4105C8Q	Methyl-accepting chemotaxis
D172_004210	ENOG4105EFZ	amidohydrolase
D172_004235	ENOG4107WP9	Histidine kinase
D172_004245	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D172_004255	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
D172_004270	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
D172_004275	ENOG4105EB3	Histidine kinase
D172_004280	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D172_004295	ENOG4105DJP	Membrane
D172_004300	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D172_004310	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
D172_004335	ENOG4105EQR	Transposase IS116 IS110 IS902
D172_004350	ENOG4107S1E	Beta-lactamase
D172_004370	ENOG4105E6M	Sulphatase-modifying factor protein
D172_004375	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D172_004385	ENOG4107S1E	Beta-lactamase
D172_004395	ENOG4105C1J	atp-dependent rna helicase
D172_004400	ENOG410620I	Diguanylate cyclase
D172_004415	ENOG4105D7W	serine acetyltransferase
D172_004425	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D172_004430	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D172_004435	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D172_004460	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
D172_004465	ENOG4105C75	arginyL-tRNA synthetase
D172_004470	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
D172_004475	ENOG4105EYA	deoxyribonuclease
D172_004485	ENOG4105EAC	phosphoserine phosphatase
D172_004505	ENOG4108JQ1	Dehydrogenase
D172_004510	ENOG4105E66	phosphoriboisomerase A
D172_004515	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
D172_004525	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
D172_004530	ENOG4105CV1	Transketolase (EC 2.2.1.1)
D172_004550	ENOG4105NBK	UPF0345 protein
D172_004555	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
D172_004560	ENOG4105K3M	)-transporter
D172_004565	ENOG4105I4A	GCN5-related N-acetyltransferase
D172_004585	ENOG4108JU8	Transcriptional regulator
D172_004605	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
D172_004610	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
D172_004615	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
D172_004620	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
D172_004625	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
D172_004630	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
D172_004635	ENOG4108UM1	dedA family
D172_004640	ENOG4108K5P	(LipO)protein
D172_004650	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D172_004660	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
D172_004665	ENOG4105CNM	Receptor
D172_004675	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D172_004685	ENOG4105CIY	formyltetrahydrofolate deformylase
D172_004720	ENOG4105CPK	Glycosyl transferase (Group 1
D172_004750	ENOG4105C8Q	Methyl-accepting chemotaxis
D172_004765	ENOG4105CJW	magnesium transporter
D172_004780	ENOG4105I7R	Adenylate cyclase
D172_004795	ENOG4105BZU	Histidine kinase
D172_004805	ENOG4105BZU	Histidine kinase
D172_004810	ENOG4108YZA	Nitrogen regulatory protein pii
D172_004820	ENOG4105BZ4	penicillin-binding protein
D172_004825	ENOG4108N3W	hemolysin secretion protein
D172_004830	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
D172_004835	ENOG4105CXT	aspartate transcarbamylase
D172_004840	ENOG4108YXA	Membrane
D172_004850	ENOG4105D4Y	metalloprotease
D172_004855	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
D172_004870	ENOG4105EYM	Major Facilitator superfamily
D172_004885	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
D172_004895	ENOG4105M85	Bola protein
D172_004900	ENOG4105RKW	reductase (By
D172_004910	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D172_004915	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D172_004920	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D172_004925	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D172_004930	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
D172_004935	ENOG4105CJ2	(LipO)protein
D172_004950	ENOG4105E2S	oxidase) subunit II
D172_004955	ENOG4105BZ9	Cytochrome C oxidase, subunit I
D172_004960	ENOG4105CCU	oxidase (Subunit III)
D172_004965	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
D172_004970	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
D172_004990	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D172_005005	ENOG4105BZU	Histidine kinase
D172_005020	ENOG4105DGU	Histone deacetylase
D172_005030	ENOG4105C5H	ABC transporter
D172_005035	ENOG4105CVG	Homoserine O-transsuccinylase
D172_005040	ENOG4105C3R	Methionine synthase
D172_005045	ENOG4105C3R	Methionine synthase
D172_005075	ENOG4105VDW	Csbd family
D172_005080	ENOG4105CQ7	ATP-dependent helicase
D172_005130	ENOG4105DQ4	alcohol dehydrogenase
D172_005135	ENOG4105F27	Major Facilitator
D172_005140	ENOG4107SDU	Methyl-accepting chemotaxis
D172_005155	ENOG4108J1Q	
D172_005175	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D172_005180	ENOG4105EW6	flavin reductase domain protein, FMN-binding
D172_005195	ENOG4105EB3	Histidine kinase
D172_005200	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D172_005225	ENOG4105BZU	Histidine kinase
D172_005235	ENOG4105CYM	Glutathione S-transferase
D172_005250	ENOG4105CR8	Transcriptional regulator
D172_005265	ENOG4105EMK	carboxylate amino acid amine transporter
D172_005270	ENOG4105DGW	oligopeptidase A
D172_005275	ENOG4105EGS	Mechanosensitive ion channel
D172_005290	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
D172_005300	ENOG4105R8A	Heat shock protein
D172_005305	ENOG4108Z5K	methylglyoxal synthase
D172_005330	ENOG4105DR5	peptidase
D172_005335	ENOG4105ERH	Fumarylacetoacetate hydrolase
D172_005350	ENOG4105DUX	Transporter
D172_005355	ENOG4105EJG	cellulose synthase
D172_005360	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
D172_005365	ENOG4107EEX	Cellulose synthase regulator protein
D172_005370	ENOG4107QZ7	Cellulose synthase catalytic subunit
D172_005385	ENOG4105U74	cellulose biosynthesis protein BcsE
D172_005390	ENOG4105D1V	cellulose synthase operon protein YhjU
D172_005410	ENOG4105EIF	outer membrane protein W
D172_005415	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D172_005425	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
D172_005440	ENOG4107YTP	response regulator receiver protein
D172_005445	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
D172_005450	ENOG4105CJR	Integral membrane protein (MviN
D172_005455	ENOG4105DTN	riboflavin biosynthesis protein ribF
D172_005460	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
D172_005465	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D172_005470	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
D172_005475	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
D172_005485	ENOG4108NEV	two component transcriptional regulator, LytTR family
D172_005525	ENOG4108YZA	Nitrogen regulatory protein pii
D172_005530	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D172_005535	ENOG4105C34	Pseudouridine synthase
D172_005540	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
D172_005545	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D172_005550	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
D172_005555	ENOG4105D9M	gamma-glutamylcysteine synthetase
D172_005565	ENOG4108JU6	CBS domain protein
D172_005570	ENOG4106KVJ	cytochrome C assembly protein
D172_005575	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D172_005580	ENOG4105K5M	30s ribosomal protein S16
D172_005585	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
D172_005590	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
D172_005595	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
D172_005605	ENOG4105CQC	Prephenate dehydratase
D172_005610	ENOG4105BZU	Histidine kinase
D172_005615	ENOG4108ZJT	translation initiation factor, Sui1
D172_005625	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D172_005635	ENOG4105CGF	Aromatic amino acid aminotransferase
D172_005640	ENOG4105E0U	tyrosine-specific transport protein
D172_005650	ENOG4105EIY	sodium-type flagellar protein motY
D172_005710	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
D172_005715	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D172_005725	ENOG4105UNS	Pfam:DUF419
D172_005750	ENOG4105KG1	l-proline 3-hydroxylase
D172_005780	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D172_005795	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
D172_005805	ENOG4105BZU	Histidine kinase
D172_005810	ENOG4108JQM	Insulinase (Peptidase family M16)
D172_005815	ENOG4108BY2	phosphohistidine phosphatase
D172_005825	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
D172_005835	ENOG4108DG9	Smr protein MutS2
D172_005840	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
D172_005845	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
D172_005875	ENOG4108BPE	-transporting atpase
D172_005885	ENOG4105MH2	YfcL protein
D172_005890	ENOG4105CFC	Transporter
D172_005900	ENOG4105C1J	atp-dependent rna helicase
D172_005905	ENOG41090BQ	Glutaredoxin
D172_005945	ENOG4105CMM	transposase
D172_005970	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D172_005985	ENOG4105DGU	Histone deacetylase
D172_005995	ENOG4105EJ9	Membrane
D172_006000	ENOG4105DVT	helicase
D172_006005	ENOG4105CQ2	DNA polymerase
D172_006010	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D172_006030	ENOG4105CFI	type iii restriction protein res subunit
D172_006040	ENOG4105CFU	surface antigen
D172_006055	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
D172_006065	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
D172_006095	ENOG4105WP7	tRNA pseudouridine synthase C
D172_006100	ENOG4105DR9	pseudouridine synthase
D172_006105	ENOG4105QDK	Flavodoxin
D172_006110	ENOG4105E9H	Lytic Murein transglycosylase
D172_006115	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
D172_006120	ENOG4105D1A	Methyltransferase
D172_006125	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D172_006130	ENOG4107RZZ	dna polymerase iii epsilon subunit
D172_006180	ENOG410804D	Sensor Signal Transduction Histidine Kinase
D172_006195	ENOG4107QPN	acyl-Coa dehydrogenase
D172_006200	ENOG4105E7A	Glutamine amidotransferase
D172_006210	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
D172_006215	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
D172_006220	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
D172_006225	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
D172_006245	ENOG4108VKG	metal-dependent hydrolase
D172_006250	ENOG41081XQ	Conserved Protein
D172_006255	ENOG4105C9M	aspartyl-trna synthetase
D172_006290	ENOG4105C1J	atp-dependent rna helicase
D172_006315	ENOG4105C28	cystathionine
D172_006330	ENOG4105KWG	Pfam:DUF1696
D172_006340	ENOG4107QPN	acyl-Coa dehydrogenase
D172_006350	ENOG4105C6T	cysteine synthase
D172_006355	ENOG4107R6U	sodium dicarboxylate symporter
D172_006360	ENOG4105WH1	Two component transcriptional regulator luxr family
D172_006365	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
D172_006415	ENOG4105BZG	amino acid carrier protein
D172_006445	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
D172_006450	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
D172_006455	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D172_006475	ENOG4105BZG	amino acid carrier protein
D172_006485	ENOG4105VUT	cytoplasmic protein
D172_006525	ENOG41088T4	Helicase IV
D172_006530	ENOG4105BZU	Histidine kinase
D172_006545	ENOG4105C8Q	Methyl-accepting chemotaxis
D172_006565	ENOG4105CMM	transposase
D172_006605	ENOG4105PBD	transposase, IS3 IS911 family protein
D172_006620	ENOG4108UJV	acyl-CoA thioesterase i
D172_006625	ENOG4108I0Y	(ABC) transporter
D172_006630	ENOG4105CV6	ABC transporter, permease
D172_006635	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
D172_006640	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
D172_006645	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D172_006650	ENOG4105E02	MotA TolQ exbB proton channel
D172_006655	ENOG4105M8F	Biopolymer transport protein exbD tolR
D172_006665	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
D172_006670	ENOG4105KCK	Peptidoglycan-associated lipoprotein
D172_006675	ENOG4105UFD	tol-pal system protein YbgF
D172_006720	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
D172_006730	ENOG4105BZU	Histidine kinase
D172_006740	ENOG4108J20	pectate lyase
D172_006755	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D172_006775	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D172_006795	ENOG4105DSY	exodeoxyribonuclease V, gamma
D172_006800	ENOG4107QKA	exodeoxyribonuclease V beta
D172_006805	ENOG4107QYX	exodeoxyribonuclease v alpha
D172_006810	ENOG4107SDU	Methyl-accepting chemotaxis
D172_006825	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
D172_006830	ENOG4105Q9Y	Universal stress protein
D172_006835	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
D172_006850	ENOG4105C59	p-type ATPase
D172_006860	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
D172_006875	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
D172_006905	ENOG4108JA2	transcriptioN-repair coupling factor
D172_006915	ENOG4105DWY	Agmatine deiminase
D172_006935	ENOG4105CBN	LysR family transcriptional regulator
D172_006955	ENOG4107RNH	Outer membrane receptor FepA
D172_006960	ENOG4109015	Biopolymer transport protein exbD tolR
D172_006975	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
D172_006985	ENOG4105E68	Sulfatase
D172_006990	ENOG4105YDX	UPF0352 protein
D172_006995	ENOG4106V8H	Nucleoid-associated protein
D172_007000	ENOG4105C03	ribonuclease
D172_007005	ENOG4105EI2	Pseudouridine synthase
D172_007010	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D172_007015	ENOG4108UHJ	MAF-like protein
D172_007020	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
D172_007025	ENOG4105VGS	50s ribosomal protein l32
D172_007030	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
D172_007035	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
D172_007040	ENOG4105CHR	reductase
D172_007045	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D172_007050	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D172_007055	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
D172_007060	ENOG4105HHA	aminodeoxychorismate lyase
D172_007065	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
D172_007070	ENOG4107QRG	dna polymerase iii
D172_007080	ENOG4105F8V	Hydrolase, tatD family
D172_007090	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
D172_007095	ENOG4108WYP	Transcriptional regulator
D172_007100	ENOG4105CR4	methylisocitrate lyase
D172_007105	ENOG4105BZN	citrate synthase
D172_007110	ENOG4108I0Z	Aconitate hydratase
D172_007115	ENOG4105C7F	AcnD-accessory protein PrpF
D172_007135	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D172_007140	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
D172_007145	ENOG4105E0C	molybdate abc transporter
D172_007150	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
D172_007155	ENOG4105D06	uba thif-type nad fad binding protein
D172_007160	ENOG4107R3J	Transporter
D172_007165	ENOG4105D9P	serine threonine protein kinase
D172_007175	ENOG4107QZF	nitrite reductase NADPH large subunit
D172_007185	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D172_007190	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
D172_007195	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
D172_007200	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D172_007205	ENOG4105M00	molybdopterin converting factor, subunit 1
D172_007210	ENOG4108ZAF	Molybdopterin
D172_007215	ENOG4108RPX	mosc domain containing protein
D172_007225	ENOG4105WH1	Two component transcriptional regulator luxr family
D172_007230	ENOG4105BZU	Histidine kinase
D172_007245	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D172_007250	ENOG4105WZK	nitrite reductase NADPH small subunit
D172_007255	ENOG4107QZF	nitrite reductase NADPH large subunit
D172_007280	ENOG4105EJC	lysr family transcriptional regulator
D172_007290	ENOG4105CHH	sulfate transporter
D172_007310	ENOG4105K64	Glycosyl transferase, family 2
D172_007315	ENOG4107T8Q	Glycosyl transferase (Group 1
D172_007345	ENOG4107QPH	glycogen) synthase
D172_007365	ENOG4105DAY	polysaccharide export protein
D172_007375	ENOG4106YYS	transcriptional regulatory protein
D172_007380	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D172_007395	ENOG4105CHW	UPF0052 protein
D172_007405	ENOG4106855	Competence protein
D172_007430	ENOG4105CT4	transporter
D172_007435	ENOG4105DT9	hydrolase family 43
D172_007445	ENOG4107RNH	Outer membrane receptor FepA
D172_007460	ENOG4105QV4	Tryptophan halogenase
D172_007475	ENOG4105EK5	Glycoside hydrolase family 8
D172_007485	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
D172_007490	ENOG4106J46	endo-1,4-beta-xylanase (EC 3.2.1.8)
D172_007505	ENOG4105DND	Transcriptional regulator
D172_007525	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D172_007535	ENOG4105CV1	Transketolase (EC 2.2.1.1)
D172_007540	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
D172_007545	ENOG4105C93	Xylose Isomerase
D172_007550	ENOG4105CMG	Carbohydrate kinase
D172_007560	ENOG4105DSG	hydrolase family 43
D172_007565	ENOG4105ETE	Transcriptional regulator (LacI family
D172_007590	ENOG41063SB	peptidase
D172_007610	ENOG4108Z6Z	Transcriptional regulator
D172_007620	ENOG4105EGI	Transcriptional regulator
D172_007660	ENOG4105CBG	Sulfatase
D172_007665	ENOG4105ENH	Sulfatase
D172_007700	ENOG4107ZSV	Receptor
D172_007710	ENOG4105ENH	Sulfatase
D172_007715	ENOG4105CXK	mandelate racemase muconate lactonizing
D172_007720	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
D172_007730	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
D172_007740	ENOG4105C26	Dehydrogenase
D172_007750	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
D172_007755	ENOG4108RTU	Aldolase
D172_007760	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D172_007765	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D172_007810	ENOG4107QI1	Mate efflux family protein
D172_007815	ENOG4108R6K	riboflavin synthase, subunit alpha
D172_007825	ENOG4105FGM	Fructosamine kinase
D172_007845	ENOG4105CI2	imidazolone-5-propionate hydrolase
D172_007860	ENOG4105VEQ	Cold shock protein
D172_007865	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
D172_007870	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D172_007880	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
D172_007885	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
D172_007890	ENOG4105C3M	thioredoxin reductase
D172_007895	ENOG4105JIM	Phosphatidylserine synthase
D172_007900	ENOG4105DCF	alanine dehydrogenase
D172_007905	ENOG4105EW9	transcriptional regulator AsnC family
D172_007910	ENOG4105CNU	cell division protein FtsK
D172_007915	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
D172_007920	ENOG4105D1H	recombination factor protein RarA
D172_007925	ENOG4105WMR	Protein CrcB homolog
D172_007930	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
D172_007985	ENOG4105JKW	Valine--pyruvate aminotransferase
D172_007995	ENOG4105CFP	Peptidase U32
D172_008000	ENOG4105E0F	Histidine kinase
D172_008005	ENOG4107EXC	regulatoR
D172_008020	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
D172_008025	ENOG4105D0S	secretion protein (HlyD
D172_008030	ENOG4105CJ1	ABC, transporter
D172_008035	ENOG4105CMI	transporter
D172_008050	ENOG4108MQB	beta-agarase
D172_008055	ENOG4105BZ1	(ABC) transporter
D172_008095	ENOG4105EZE	Cupin 4 family protein
D172_008100	ENOG4107QTF	adenylosuccinate lyase
D172_008105	ENOG41075W9	High frequency lysogenization protein HflD homolog
D172_008110	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
D172_008125	ENOG4108R99	pseudouridine synthase
D172_008130	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
D172_008140	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
D172_008145	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
D172_008150	ENOG4108MN8	Membrane
D172_008185	ENOG4108ZGC	gaf domain protein
D172_008195	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
D172_008200	ENOG4105CN1	protease
D172_008205	ENOG4105DFD	Na H antiporter
D172_008210	ENOG4105CD8	aminopeptidase N
D172_008225	ENOG4105D25	secreted protein
D172_008230	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
D172_008240	ENOG4105C7I	Dehydrogenase
D172_008245	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D172_008250	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
D172_008255	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
D172_008265	ENOG4105C5H	ABC transporter
D172_008280	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
D172_008285	ENOG4105BZ1	(ABC) transporter
D172_008290	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
D172_008295	ENOG4105W49	UPF0434 protein
D172_008300	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
D172_008305	ENOG4108W1A	pseudouridine synthase
D172_008310	ENOG4105CUZ	uba thif-type nad fad binding protein
D172_008315	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
D172_008325	ENOG4105BZN	citrate synthase
D172_008330	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
D172_008335	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
D172_008340	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
D172_008345	ENOG4105E33	succinate dehydrogenase
D172_008350	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
D172_008355	ENOG4105C7S	Dehydrogenase
D172_008360	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
D172_008365	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
D172_008375	ENOG4105CX6	glutaminyL-tRNA synthetase
D172_008380	ENOG41090R7	Ferric uptake
D172_008385	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
D172_008390	ENOG4105NNH	LexA regulated protein
D172_008400	ENOG4105EV9	Alpha Beta Hydrolase
D172_008405	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
D172_008410	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
D172_008415	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
D172_008420	ENOG4107R0V	Pyruvate dehydrogenase
D172_008425	ENOG4105CPP	Dehydrogenase, E1 component
D172_008455	ENOG4108IUW	ABC transporter
D172_008460	ENOG4108SDH	ABC, transporter
D172_008465	ENOG4105BZU	Histidine kinase
D172_008475	ENOG41080BH	prolyl-tRNA synthetase
D172_008480	ENOG4108R96	Methyltransferase, YaeB family
D172_008495	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
D172_008500	ENOG4105BZJ	Electron transfer flavoprotein
D172_008505	ENOG4105C10	Electron transfer flavoprotein
D172_008510	ENOG4105C5S	asparaginyl-tRNA synthetase
D172_008525	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D172_008530	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
D172_008545	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
D172_008550	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
D172_008560	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
D172_008565	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
D172_008575	ENOG4105D0M	Protease HtpX homolog
D172_008580	ENOG4107XDR	Lactoylglutathione lyase
D172_008640	ENOG4105CJ1	ABC, transporter
D172_008655	ENOG4105E0K	tonB-dependent siderophore receptor
D172_008665	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D172_008700	ENOG4105C5H	ABC transporter
D172_008705	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
D172_008710	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
D172_008730	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D172_008735	ENOG4107R1I	NAD-dependent malic enzyme
D172_008745	ENOG4105EXU	Membrane
D172_008765	ENOG4105BZU	Histidine kinase
D172_008780	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D172_008805	ENOG4107YTP	response regulator receiver protein
D172_008810	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D172_008820	ENOG4105F8C	transglutaminase domain-containing protein
D172_008825	ENOG4105D3Y	Na H antiporter
D172_008845	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
D172_008850	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
D172_008855	ENOG4108WUH	Transcriptional regulator, TetR family
D172_008860	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
D172_008865	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
D172_008920	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
D172_008990	ENOG4105CHR	reductase
D172_008995	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D172_009000	ENOG4105E39	Enoyl-CoA hydratase
D172_009005	ENOG4105E39	Enoyl-CoA hydratase
D172_009015	ENOG4105C26	Dehydrogenase
D172_009020	ENOG4105CHU	acetyl-coa acetyltransferase
D172_009030	ENOG4105C1G	acyl-Coa dehydrogenase
D172_009035	ENOG4107QX3	carboxylase
D172_009050	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
D172_009055	ENOG4105D6N	CoA-transferase, subunit a
D172_009065	ENOG4105ETT	transcriptional Regulator, LysR family
D172_009070	ENOG4105E0X	reductase
D172_009075	ENOG4105P4J	Allophanate hydrolase, subunit 1
D172_009080	ENOG4107R7A	Allophanate hydrolase subunit 2
D172_009095	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
D172_009100	ENOG4105CAQ	asparagine synthetase
D172_009115	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
D172_009120	ENOG4105C94	Transporter
D172_009125	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D172_009130	ENOG4105C2X	Arabinose 5-phosphate isomerase
D172_009135	ENOG4105C72	UPF0176 protein
D172_009155	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
D172_009160	ENOG4105CFV	Tetratricopeptide repeat protein
D172_009170	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D172_009175	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
D172_009180	ENOG4105CAT	Cytidine monophosphate kinase
D172_009185	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
D172_009190	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
D172_009195	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D172_009200	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D172_009205	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D172_009210	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D172_009215	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D172_009220	ENOG4105C26	Dehydrogenase
D172_009225	ENOG4105CHR	reductase
D172_009230	ENOG4105CPQ	Dehydrogenase
D172_009240	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
D172_009245	ENOG41061MV	Arylsulfatase
D172_009265	ENOG4105EMN	RNA polymerase sigma factor
D172_009270	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
D172_009280	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
D172_009290	ENOG4107RJ1	sodium solute
D172_009305	ENOG4105CMR	udp-glucose 4-epimerase
D172_009315	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
D172_009325	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D172_009340	ENOG4107YCY	Transcriptional regulator
D172_009350	ENOG4105CBG	Sulfatase
D172_009365	ENOG4105PBD	transposase, IS3 IS911 family protein
D172_009370	ENOG4108XC3	NADH ubiquinone oxidoreductase
D172_009400	ENOG4105EV8	ectoine hydroxylase
D172_009435	ENOG4105QRC	ig domain protein group 2 domain protein
D172_009445	ENOG4107QPD	alcohol dehydrogenase
D172_009450	ENOG4107XVH	Transcriptional regulator
D172_009465	ENOG4106A3M	Cytochrome p-450
D172_009470	ENOG4105DIA	mandelate racemase muconate lactonizing
D172_009485	ENOG4105UGU	tonB-dependent Receptor
D172_009490	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D172_009510	ENOG41069NU	Nitroreductase
D172_009520	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D172_009525	ENOG4105D07	Signal peptide peptidase, SppA
D172_009530	ENOG4105HDK	L-asparaginase
D172_009535	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
D172_009540	ENOG4105CA9	Pyruvate kinase
D172_009545	ENOG4108NEV	two component transcriptional regulator, LytTR family
D172_009550	ENOG4105C2F	Histidine kinase
D172_009555	ENOG4105CHH	sulfate transporter
D172_009560	ENOG4108XM1	transcriptional regulator AsnC family
D172_009570	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
D172_009575	ENOG41082NX	50s ribosomal protein l35
D172_009580	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
D172_009585	ENOG4105C22	threonyL-tRNA synthetase
D172_009595	ENOG4105CEY	Amp-dependent synthetase and ligase
D172_009600	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
D172_009605	ENOG4108W15	Protein of unknown function (DUF1456)
D172_009610	ENOG4105D60	lipoprotein releasing system transmembrane protein
D172_009615	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D172_009620	ENOG4105D60	lipoprotein releasing system transmembrane protein
D172_009625	ENOG4105CC0	LysR family Transcriptional regulator
D172_009635	ENOG4105C4W	S-formylglutathione hydrolase
D172_009665	ENOG4107RX2	synthase
D172_009670	ENOG4105ECQ	AraC Family Transcriptional Regulator
D172_009675	ENOG4105KT7	mgtC SapB transporter
D172_009685	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D172_009690	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
D172_009725	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D172_009730	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D172_009740	ENOG4108JJ7	ABC transporter
D172_009745	ENOG4105C9K	Endothelin-converting enzyme 1
D172_009750	ENOG4105CDY	transcriptional regulatory protein
D172_009765	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D172_009770	ENOG4108UHU	Aldolase
D172_009775	ENOG4105C01	Dihydroxy-acid dehydratase
D172_009780	ENOG4105ETE	Transcriptional regulator (LacI family
D172_009785	ENOG4105CHC	glucokinase (EC 2.7.1.2)
D172_009790	ENOG4105DDV	Transcriptional regulator (LacI family
D172_009800	ENOG4105DY9	regulatoR
D172_009840	ENOG4108IUK	alpha amylase, catalytic
D172_009845	ENOG4105QV4	Tryptophan halogenase
D172_009855	ENOG4105CG3	alpha amylase, catalytic region
D172_009860	ENOG4108TEB	UPF0114 protein
D172_009870	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D172_009880	ENOG4105CK2	sodium dicarboxylate symporter
D172_009885	ENOG4105ERU	peptidase
D172_009890	ENOG4108M0H	Extracellular lipase
D172_009895	ENOG4105UBK	short-chain dehydrogenase reductase
D172_009900	ENOG4105FE9	pseudouridine synthase
D172_009905	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
D172_009930	ENOG4105DHI	Methyltransferase
D172_009935	ENOG4105PQ6	UPF0208 membrane protein
D172_009940	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
D172_009945	ENOG4108DNC	Involved in acetate metabolism (By similarity)
D172_009960	ENOG4105KUZ	arsenate reductase
D172_009965	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D172_009985	ENOG4105E18	UPF0276 protein
D172_010005	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
D172_010010	ENOG4107MBR	17 kDa surface antigen
D172_010015	ENOG4105CHM	Aminotransferase
D172_010035	ENOG4105DHP	deoxycytidine triphosphate deaminase
D172_010040	ENOG4105D1F	ATP-binding protein
D172_010045	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
D172_010050	ENOG4108UHU	Aldolase
D172_010055	ENOG4105C3F	Signal peptidase i
D172_010070	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
D172_010120	ENOG4105DS1	cytochrome b561
D172_010130	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
D172_010135	ENOG4105DB7	PHP domain protein
D172_010140	ENOG4105CRQ	synthase (Component I)
D172_010145	ENOG4105DDQ	anthranilate synthase
D172_010150	ENOG4108I0Q	anthranilate phosphoribosyltransferase
D172_010155	ENOG4105DK0	Indole-3-glycerol phosphate synthase
D172_010160	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D172_010170	ENOG4108Z0Z	intracellular protease Pfpi family
D172_010180	ENOG4107835	probably involved in intracellular septation (By similarity)
D172_010190	ENOG4105C8J	)-transporter
D172_010195	ENOG4105K9H	YciI-like protein
D172_010205	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D172_010210	ENOG4105IFJ	Histidine kinase
D172_010225	ENOG4105DSF	transport protein
D172_010230	ENOG4105ECP	epimerase
D172_010250	ENOG4105CT4	transporter
D172_010255	ENOG41060NJ	transcriptional regulator
D172_010270	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
D172_010285	ENOG4107RNH	Outer membrane receptor FepA
D172_010290	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D172_010300	ENOG4105F57	Anthranilate dioxygenase reductase
D172_010305	ENOG4105D8V	Glucose sorbosone dehydrogenase
D172_010325	ENOG41082W1	Cupin 2, conserved barrel domain protein
D172_010340	ENOG4108R5S	membrane
D172_010345	ENOG4108IXY	short-chain dehydrogenase reductase
D172_010380	ENOG4105QV4	Tryptophan halogenase
D172_010395	ENOG4105CT4	transporter
D172_010405	ENOG4105DUM	transcriptional regulator, lysR family
D172_010440	ENOG4105E18	UPF0276 protein
D172_010460	ENOG4105EEQ	Na H antiporter
D172_010470	ENOG4108YIQ	Alpha beta hydrolase
D172_010595	ENOG4105ED4	portal protein
D172_010620	ENOG41073TP	transcriptional regulator
D172_010640	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
D172_010680	ENOG4105RDA	repressor
D172_010710	ENOG4105DFP	Integrase
D172_010715	ENOG4105CJB	Exodeoxyribonuclease I
D172_010720	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D172_010725	ENOG4108V06	Glutathione peroxidase
D172_010730	ENOG4105C5I	Dehydrogenase
D172_010735	ENOG4105C8J	)-transporter
D172_010745	ENOG4105CFH	Aspartokinase
D172_010775	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D172_010785	ENOG4105KRS	Proteinase inhibitor
D172_010815	ENOG4105EXG	Transcriptional regulator
D172_010845	ENOG4108RCM	Nitroreductase
D172_010850	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
D172_010860	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D172_010865	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
D172_010870	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
D172_010875	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
D172_010890	ENOG41088PD	hydrolase
D172_010900	ENOG4105C2C	drug resistance transporter, Bcr CflA
D172_010905	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D172_010910	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
D172_010915	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
D172_010925	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
D172_010930	ENOG4105BZU	Histidine kinase
D172_010935	ENOG4105BZ8	glutamate synthase
D172_010940	ENOG4105CBC	glutamate synthase
D172_010950	ENOG4105C19	ABC transporter
D172_010955	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D172_010960	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D172_010965	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D172_010975	ENOG4105M2J	Glutaredoxin
D172_010980	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D172_010985	ENOG4105CYN	Serine protein kinase
D172_010990	ENOG4106AKX	UPF0229 protein
D172_010995	ENOG4105ED1	spovr family
D172_011000	ENOG4105Q9Y	Universal stress protein
D172_011010	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D172_011015	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
D172_011020	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D172_011025	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
D172_011030	ENOG4105D3G	Pseudouridine synthase
D172_011040	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
D172_011045	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
D172_011050	ENOG4107QMP	dna polymerase iii subunits gamma and tau
D172_011055	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
D172_011065	ENOG4105E18	UPF0276 protein
D172_011075	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
D172_011095	ENOG410822N	TonB family
D172_011100	ENOG4109015	Biopolymer transport protein exbD tolR
D172_011125	ENOG4105EKE	dihydroorotase
D172_011135	ENOG4105DZ2	Transcriptional regulator
D172_011140	ENOG4107S90	membrAne
D172_011145	ENOG4107QNR	UPF0135 protein
D172_011165	ENOG4105CI2	imidazolone-5-propionate hydrolase
D172_011180	ENOG4107RDP	Dehydrogenase
D172_011190	ENOG4105CRQ	synthase (Component I)
D172_011200	ENOG4105EJQ	L-serine dehydratase
D172_011205	ENOG4105C7N	Xanthine uracil vitamin C permease
D172_011255	ENOG4105EST	Metal Dependent Phosphohydrolase
D172_011260	ENOG4105DR4	Methyltransferase
D172_011270	ENOG4105BZU	Histidine kinase
D172_011275	ENOG4105CQ7	ATP-dependent helicase
D172_011280	ENOG4105D44	asparaginase
D172_011290	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
D172_011295	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
D172_011300	ENOG4107QP8	phosphohexose isomerase
D172_011305	ENOG4105C3J	Cysteine desulfurase
D172_011325	ENOG4105ERG	peptidase m48, ste24p
D172_011330	ENOG4105K89	arsenate reductase
D172_011335	ENOG4105CS1	NAD(P)H quinone oxidoreductase
D172_011350	ENOG4105E3I	toluene tolerance
D172_011355	ENOG41061N2	exported protein
D172_011360	ENOG4105DWD	nucleoside recognition domain protein
D172_011365	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D172_011370	ENOG4105RH4	Glycine cleavage system transcriptional repressor
D172_011375	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D172_011410	ENOG4105PBD	transposase, IS3 IS911 family protein
D172_011425	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
D172_011430	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
D172_011455	ENOG4105DR4	Methyltransferase
D172_011460	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
D172_011495	ENOG41062P1	Diguanylate cyclase phosphodiesterase
D172_011500	ENOG4105DGN	Electron transport complex
D172_011515	ENOG4105D6A	Electron transport complex
D172_011520	ENOG4108UQQ	Electron transport complex
D172_011525	ENOG4105DZB	Electron transport complex
D172_011530	ENOG4105CSM	endonuclease III
D172_011550	ENOG4105PBD	transposase, IS3 IS911 family protein
D172_011560	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
D172_011590	ENOG4105CXN	decarboxylase
D172_011610	ENOG4105CMM	transposase
D172_011630	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D172_011635	ENOG4105D2N	Aldolase
D172_011640	ENOG4108UHU	Aldolase
D172_011645	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D172_011650	ENOG4105DPW	Major facilitator superfamily MFS_1
D172_011655	ENOG4105M5J	Cupin 2, conserved barrel domain protein
D172_011660	ENOG4105EY3	heparinase II III family protein
D172_011670	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D172_011675	ENOG4108UYE	Lactoylglutathione lyase
D172_011680	ENOG4105KSC	Transcriptional regulator, TraR DksA family
D172_011780	ENOG4105E0X	reductase
D172_011795	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
D172_011800	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
D172_011805	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
D172_011815	ENOG4105DSW	Fusaric acid resistance protein
D172_011820	ENOG4105Y49	secretion protein, HlyD family
D172_011830	ENOG4108M3P	Membrane
D172_011850	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
D172_011855	ENOG4105KK4	UPF0060 membrane protein
D172_011875	ENOG4105EXN	Sulfate transport protein CysZ
D172_011880	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
D172_011885	ENOG4105M08	Membrane
D172_011895	ENOG4105ETT	transcriptional Regulator, LysR family
D172_011900	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D172_011905	ENOG4105JHY	Membrane
D172_011920	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D172_011925	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
D172_011930	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D172_011935	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
D172_011940	ENOG4108986	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
D172_011945	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
D172_011950	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D172_011955	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
D172_011960	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
D172_011965	ENOG4105C3G	gtp-binding protein
D172_012025	ENOG4105BZU	Histidine kinase
D172_012030	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
D172_012040	ENOG4105C9A	Phoh family
D172_012045	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
D172_012050	ENOG4108JU5	Magnesium and cobalt efflux protein
D172_012055	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
D172_012100	ENOG4105C3S	Mate efflux family protein
D172_012110	ENOG4108VP3	Lysine exporter protein (LysE YggA)
D172_012125	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D172_012130	ENOG4105DAN	ATP-dependent protease
D172_012135	ENOG4107PAI	alpha helical protein
D172_012140	ENOG4105C8T	Leucyl-tRNA synthetase
D172_012155	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
D172_012160	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
D172_012165	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
D172_012170	ENOG4105CJN	penicillin-binding protein
D172_012175	ENOG4105CNI	cell division protein FtsW
D172_012180	ENOG4105K6T	rare lipoprotein A
D172_012185	ENOG4105DZ1	carboxypeptidase
D172_012195	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D172_012200	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
D172_012210	ENOG4105VFU	Rna-binding protein
D172_012225	ENOG4105PBD	transposase, IS3 IS911 family protein
D172_012340	ENOG4105C59	p-type ATPase
D172_012355	ENOG4105KJM	monovalent cation h antiporter subunit g
D172_012360	ENOG4105W4C	monovalent cation H antiporter subunit F
D172_012365	ENOG4105SC1	monovalent cation H antiporter subunit E
D172_012370	ENOG4107R4Z	monovalent cation h antiporter subunit d
D172_012375	ENOG4108ZE9	Monovalent cation H antiporter subunit C
D172_012380	ENOG4105D65	subunit l
D172_012395	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
D172_012400	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
D172_012405	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
D172_012410	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
D172_012415	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
D172_012420	ENOG4105CHV	Transcription elongation factor NusA
D172_012425	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
D172_012440	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
D172_012465	ENOG4105D3R	alkyl hydroperoxide reductase
D172_012510	ENOG4105CMM	transposase
D172_012550	ENOG4105BZU	Histidine kinase
D172_012560	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D172_012565	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
D172_012570	ENOG4105C0B	DNA polymerase III (alpha subunit)
D172_012575	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D172_012580	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D172_012585	ENOG4105C4M	(Ubiquinol oxidase) subunit I
D172_012590	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
D172_012605	ENOG4108JJ8	(ABC) transporter
D172_012610	ENOG4108J20	pectate lyase
D172_012615	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D172_012620	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D172_012625	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D172_012630	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
D172_012635	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D172_012640	ENOG4105DZP	Membrane-associated zinc metalloprotease
D172_012645	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
D172_012650	ENOG4105KNE	Phosphatidate cytidylyltransferase
D172_012655	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
D172_012660	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
D172_012665	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
D172_012670	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
D172_012675	ENOG4105CE9	30S ribosomal protein S2
D172_012680	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
D172_012685	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
D172_012690	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
D172_012705	ENOG41090A4	Pterin carbinolamine dehydratase
D172_012710	ENOG4105MIR	Phenylalanine 4-monooxygenase
D172_012715	ENOG4105C28	cystathionine
D172_012725	ENOG4105CM6	amino acid regulated cytosolic protein
D172_012730	ENOG4105FM1	phage shock protein C
D172_012735	ENOG4105YYT	phage shock protein B
D172_012740	ENOG41087YS	Phage shock protein A
D172_012745	ENOG4105E51	psp operon transcriptional activator
D172_012750	ENOG4105DEF	Extracellular solute-binding protein, family 5
D172_012755	ENOG4108I5W	peptide transport system, permease protein
D172_012760	ENOG4108EU3	peptide transport system, permease
D172_012765	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
D172_012770	ENOG4108JQ2	peptide transport system atp-binding protein
D172_012775	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
D172_012780	ENOG4105EIN	peptidylprolyl cis-trans isomerase
D172_012785	ENOG4105K70	DNA-binding protein
D172_012790	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D172_012795	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
D172_012800	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D172_012805	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
D172_012835	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
D172_012840	ENOG4105C8N	cysteinyl-tRNA synthetase
D172_012845	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D172_012860	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
D172_012870	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
D172_012875	ENOG4105E96	Colicin v production protein
D172_012885	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
D172_012890	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
D172_012895	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
D172_012910	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
D172_012915	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D172_012920	ENOG4105CHU	acetyl-coa acetyltransferase
D172_012925	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D172_012940	ENOG4107QVM	von Willebrand factor, type A
D172_012955	ENOG4105EMN	RNA polymerase sigma factor
D172_012970	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D172_012975	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D172_013010	ENOG4105C8Q	Methyl-accepting chemotaxis
D172_013025	ENOG4105CP7	Triose-phosphate isomerase
D172_013030	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
D172_013035	ENOG4105EEI	dihydropteroate synthase
D172_013040	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D172_013045	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
D172_013050	ENOG4105HBR	Rna-binding protein
D172_013080	ENOG4107EXC	regulatoR
D172_013085	ENOG4105E0F	Histidine kinase
D172_013090	ENOG4105C8J	)-transporter
D172_013095	ENOG4107YB6	acetyltransferase, (GNAT) family
D172_013100	ENOG4108N23	SpoOM-related protein
D172_013105	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
D172_013115	ENOG4105JJR	Histidine kinase
D172_013120	ENOG4107EXC	regulatoR
D172_013135	ENOG4106TD9	Diguanylate cyclase
D172_013140	ENOG4105EMY	transcriptional regulator
D172_013145	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D172_013150	ENOG41069D7	Methyl-accepting chemotaxis
D172_013155	ENOG41082IR	Excinuclease ABC C subunit domain protein
D172_013160	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D172_013165	ENOG4105VDB	UPF0125 protein
D172_013170	ENOG4108Z1B	Cyclase dehydrase
D172_013175	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
D172_013180	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D172_013185	ENOG4105D3R	alkyl hydroperoxide reductase
D172_013195	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
D172_013200	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D172_013205	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
D172_013215	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
D172_013220	ENOG4105X2V	dna damage-inducible protein
D172_013225	ENOG4105CK7	Sodium proline symporter
D172_013230	ENOG4105D58	Diguanylate phosphodiesterase
D172_013235	ENOG410903C	(LipO)protein
D172_013240	ENOG4108M1T	Cytochrome c-type biogenesis protein
D172_013245	ENOG4108M1T	Cytochrome c-type biogenesis protein
D172_013250	ENOG4107QX9	Thiol disulfide interChange protein
D172_013255	ENOG4105DA4	cytochrome c-type biogenesis protein
D172_013260	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
D172_013265	ENOG4105X3C	heme exporter protein
D172_013270	ENOG41060IM	Heme exporter protein
D172_013275	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
D172_013280	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
D172_013300	ENOG4108V3W	Chemotaxis protein, CheW
D172_013310	ENOG4107QJE	Chromosome Partitioning Protein
D172_013315	ENOG4108SEK	ompa motb domain protein
D172_013320	ENOG4105E14	MotA TolQ exbB proton channel
D172_013325	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D172_013330	ENOG4105CBS	Chea signal transduction histidine kinase
D172_013335	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
D172_013340	ENOG4108VYJ	response regulator receiver protein
D172_013345	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D172_013350	ENOG4107R21	site-determining protein
D172_013355	ENOG4105FZW	flagellar biosynthesis regulator FlhF
D172_013360	ENOG4105D7B	Flagellar biosynthesis protein flha
D172_013365	ENOG4105D00	flagellar biosynthetic protein flhB
D172_013370	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
D172_013375	ENOG4105VS8	Flagellar biosynthetic protein fliq
D172_013380	ENOG4105CN7	Flagellar biosynthetic protein FliP
D172_013385	ENOG4105K0P	flagellar biosynthesis protein
D172_013390	ENOG4105DD5	Flagellar motor switch protein
D172_013395	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D172_013405	ENOG4105WF4	Flagellar hook-length control protein
D172_013415	ENOG4108JIR	Flagellum-specific ATP synthase
D172_013425	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D172_013430	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
D172_013435	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
D172_013440	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D172_013445	ENOG4105BZU	Histidine kinase
D172_013450	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D172_013455	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D172_013470	ENOG4105DTS	flagellar hook-associated
D172_013475	ENOG41063QE	flagellar protein FlaG
D172_013480	ENOG4105I03	Flagellin
D172_013485	ENOG4105I03	Flagellin
D172_013490	ENOG4105I03	Flagellin
D172_013500	ENOG4105E1Q	flagellar hook-associated protein
D172_013505	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
D172_013510	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D172_013515	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D172_013520	ENOG4105CGA	flagellar basal-body rod protein FlgG
D172_013525	ENOG4108KPB	Flagellar basal-body rod protein FlgF
D172_013530	ENOG4105BZE	flagellar hook protein, FlgE
D172_013540	ENOG4108ZC9	flagellar basal-body rod protein flgc
D172_013545	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
D172_013550	ENOG4105BZU	Histidine kinase
D172_013555	ENOG4107R88	Chemotaxis protein (CheV)
D172_013590	ENOG4105EHV	domain protein
D172_013655	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
D172_013660	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
D172_013665	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
D172_013670	ENOG4105HF0	Membrane
D172_013675	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
D172_013680	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
D172_013685	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
D172_013690	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
D172_013695	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
D172_013700	ENOG4105DXN	mazG family
D172_013705	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D172_013710	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
D172_013715	ENOG4105BZU	Histidine kinase
D172_013720	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
D172_013725	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
D172_013735	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
D172_013740	ENOG4105C3F	Signal peptidase i
D172_013745	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
D172_013765	ENOG4105EMN	RNA polymerase sigma factor
D172_013770	ENOG4108IYU	L-aspartate oxidase
D172_013780	ENOG4105Y75	tpr repeat protein
D172_013790	ENOG4108YZY	peptidylprolyl cis-trans isomerase
D172_013805	ENOG4108W5H	UPF0263 protein
D172_013810	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D172_013820	ENOG41067MG	lrgb family
D172_013825	ENOG4105D64	Mechanosensitive ion channel
D172_013830	ENOG4105EW9	transcriptional regulator AsnC family
D172_013840	ENOG4105CPI	Metal Dependent Phosphohydrolase
D172_013880	ENOG4105BZS	acriflavin resistance protein
D172_013885	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D172_013890	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D172_013895	ENOG4108VPT	UPF0234 protein
D172_013905	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
D172_013910	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
D172_013915	ENOG41062JF	Transcriptional regulator
D172_013920	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
D172_013955	ENOG4105CH7	arginosuccinase
D172_013960	ENOG4105CDH	Citrulline--aspartate ligase
D172_013970	ENOG4105CAS	nag kinase
D172_013975	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
D172_013985	ENOG4105DY8	decarboxylase
D172_013990	ENOG4105BZU	Histidine kinase
D172_013995	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D172_014000	ENOG4105E3A	(ABC) transporter
D172_014005	ENOG4105DA5	(ABC) transporter
D172_014010	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
D172_014015	ENOG4105DFU	Cell wall formation (By similarity)
D172_014020	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
D172_014025	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D172_014035	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
D172_014040	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D172_014060	ENOG4105DND	Transcriptional regulator
D172_014070	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
D172_014075	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
D172_014115	ENOG4105PBD	transposase, IS3 IS911 family protein
D172_014130	ENOG4105X6C	Flagellar basal body-associated protein FliL
D172_014135	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
D172_014140	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
D172_014145	ENOG4105CPQ	Dehydrogenase
D172_014150	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D172_014155	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
D172_014160	ENOG4105DKP	glycosyl transferase, family 9
D172_014165	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
D172_014170	ENOG4105CG5	Glycosyl transferase (Group 1
D172_014185	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
D172_014190	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
D172_014195	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
D172_014205	ENOG4105WXT	Conserved Protein
D172_014210	ENOG410689M	(LipO)protein
D172_014220	ENOG4108ETH	Formylglycinamide ribotide synthetase
D172_014225	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
D172_014230	ENOG4108Z6B	deaminase
D172_014235	ENOG4107RE1	Inosine-guanosine kinase
D172_014240	ENOG4105CSV	Glutaminase
D172_014270	ENOG4107QR8	Thioredoxin
D172_014275	ENOG4105CH2	amidohydrolase
D172_014280	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D172_014290	ENOG4106VK6	Flagellar motor protein
D172_014295	ENOG4105E14	MotA TolQ exbB proton channel
D172_014300	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D172_014305	ENOG4105CTB	Polyprenyl synthetase
D172_014310	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D172_014315	ENOG4105BZU	Histidine kinase
D172_014320	ENOG4108ZAI	phosphatidylglycerophosphatase a
D172_014325	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
D172_014330	ENOG4107YIM	Involved in the transcription termination process (By similarity)
D172_014335	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
D172_014350	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D172_014355	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
D172_014360	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D172_014365	ENOG4105D98	threonine synthase
D172_014370	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
D172_014380	ENOG4107YTP	response regulator receiver protein
D172_014385	ENOG4105BZU	Histidine kinase
D172_014390	ENOG4105DH7	May be involved in recombination (By similarity)
D172_014400	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D172_014405	ENOG4105PW4	Sugar fermentation stimulation protein homolog
D172_014410	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D172_014415	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
D172_014420	ENOG4105DJ0	Poly(A) Polymerase
D172_014425	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D172_014430	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
D172_014435	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
D172_014450	ENOG4105BZU	Histidine kinase
D172_014455	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D172_014460	ENOG4105D2N	Aldolase
D172_014465	ENOG4105BZA	Phosphoglycerate kinase
D172_014470	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D172_014475	ENOG4108K0B	C-di-gmp phosphodiesterase
D172_014495	ENOG4107QN1	sodium solute
D172_014505	ENOG4105BZU	Histidine kinase
D172_014530	ENOG4105BZU	Histidine kinase
D172_014550	ENOG4105CJ2	(LipO)protein
D172_014585	ENOG4105ECQ	AraC Family Transcriptional Regulator
D172_014595	ENOG4108VGI	doxx family
D172_014600	ENOG4108I6A	alcohol dehydrogenase
D172_014605	ENOG4105CF7	AraC family transcriptional regulator
D172_014655	ENOG4108Z4K	mutator MutT protein
D172_014660	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D172_014695	ENOG4108SDH	ABC, transporter
D172_014700	ENOG4108IUW	ABC transporter
D172_014710	ENOG4107RJJ	Transcriptional regulator
D172_014715	ENOG4105DVE	abc transporter atp-binding protein
D172_014740	ENOG4105PE1	Receptor
D172_014745	ENOG4105CA0	peroxidase
D172_014755	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D172_014765	ENOG4108Y50	Glutathione-dependent formaldehyde-activating Gfa
D172_014785	ENOG4106032	Glutathionylspermidine synthase
D172_014795	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
D172_014815	ENOG4108S01	response regulator
D172_014820	ENOG4108ZGX	Histidine kinase
D172_014830	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
D172_014840	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
D172_014845	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D172_014850	ENOG4105BZU	Histidine kinase
D172_014855	ENOG4107TCE	N-acetyltransferase
D172_014865	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
D172_014895	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
D172_014900	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D172_014905	ENOG4105PAD	Hydrolase
D172_014910	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D172_014915	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
D172_014920	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
D172_014925	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
D172_014930	ENOG4105CPF	Cell wall formation (By similarity)
D172_014935	ENOG4105DFU	Cell wall formation (By similarity)
D172_014940	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D172_014945	ENOG4105CNI	cell division protein FtsW
D172_014950	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
D172_014955	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
D172_014960	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
D172_014965	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
D172_014970	ENOG4105CJN	penicillin-binding protein
D172_014975	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
D172_014980	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
D172_014985	ENOG4108V6E	Cell division protein mraZ
D172_015005	ENOG4105CHF	Glutathione S-transferase
D172_015010	ENOG4105EUB	pirin domain protein
D172_015020	ENOG4107U9T	Pfam:Ribonuclease_BN
D172_015035	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
D172_015040	ENOG4105CFH	Aspartokinase
D172_015045	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D172_015050	ENOG4105Y3E	Modulates RecA activity (By similarity)
D172_015060	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
D172_015075	ENOG4105CMR	udp-glucose 4-epimerase
D172_015080	ENOG4107E2E	PKHD-type hydroxylase
D172_015085	ENOG4108ESX	Receptor
D172_015105	ENOG4109015	Biopolymer transport protein exbD tolR
D172_015120	ENOG4105D6Z	AFG1 family ATPase
D172_015125	ENOG4105I08	Pseudouridine synthase
D172_015140	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D172_015155	ENOG4105KHC	sulfurtransferase
D172_015160	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
D172_015180	ENOG4105BZU	Histidine kinase
D172_015190	ENOG4105C8V	SAICAR synthetase
D172_015195	ENOG4108I0Y	(ABC) transporter
D172_015215	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
D172_015220	ENOG4105EHV	domain protein
D172_015235	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
D172_015260	ENOG4105D3Q	Sugar transferase
D172_015270	ENOG4105EXC	Acyl-transferase
D172_015310	ENOG4105CHR	reductase
D172_015315	ENOG4107SET	aldo keto reductase
D172_015320	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D172_015325	ENOG4105C5E	polysaccharide biosynthesis protein
D172_015335	ENOG4107ZF2	Phosphatase
D172_015340	ENOG4105DAY	polysaccharide export protein
D172_015345	ENOG4106ECQ	phosphomannomutase
D172_015350	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
D172_015355	ENOG4105CPK	Glycosyl transferase (Group 1
D172_015360	ENOG4108TJN	glycosyl transferase group 1
D172_015375	ENOG4108UW5	maltose o-acetyltransferase
D172_015395	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
D172_015400	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
D172_015405	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
D172_015420	ENOG4105DAY	polysaccharide export protein
D172_015425	ENOG4108NE3	Salt-induced outer membrane protein
D172_015430	ENOG4105D64	Mechanosensitive ion channel
D172_015455	ENOG4107YM4	Beta-lactamase domain-containing protein
D172_015460	ENOG4105F8J	Adenylate Guanylate cyclase
D172_015465	ENOG4105DHT	Metal Dependent Phosphohydrolase
D172_015480	ENOG4108ZIT	Ferredoxin, 2FE-2S
D172_015485	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
D172_015490	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
D172_015495	ENOG4108Z4V	iron-sulfur cluster assembly
D172_015500	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
D172_015505	ENOG4105C3J	Cysteine desulfurase
D172_015515	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
D172_015520	ENOG4105ETE	Transcriptional regulator (LacI family
D172_015530	ENOG4108HKT	sucrose-6-phosphate hydrolase
D172_015545	ENOG4105C27	TonB-dependent Receptor Plug
D172_015550	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
D172_015555	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D172_015560	ENOG4105DGW	oligopeptidase A
D172_015570	ENOG4105DC8	reductase
D172_015715	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
D172_015725	ENOG4105QD6	exported protein
D172_015730	ENOG4105C03	ribonuclease
D172_015735	ENOG4108Z03	MAF-like protein
D172_015740	ENOG4105VQ7	Rod shape-determining protein MreD
D172_015745	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
D172_015750	ENOG4105DFF	Rod shape-determining protein mreb
D172_015760	ENOG4105K6H	D-cysteine desulfhydrase
D172_015770	ENOG4105BZU	Histidine kinase
D172_015775	ENOG4108UUM	single-stranded DNA-binding protein
D172_015780	ENOG4107RDB	Major Facilitator
D172_015785	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D172_015790	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D172_015805	ENOG4105C31	Tryptophanyl-tRNA synthetase
D172_015810	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D172_015815	ENOG4105DJV	ribulose-phosphate 3-epimerase
D172_015825	ENOG4105DFE	Dna adenine methylase
D172_015830	ENOG4105EGB	membrane protein DamX
D172_015835	ENOG4105D49	3-dehydroquinate synthase
D172_015845	ENOG4105E4G	Type IV pilus
D172_015870	ENOG4108JQC	penicillin-binding protein 1A
D172_015875	ENOG4105CFH	Aspartokinase
D172_015880	ENOG4105C28	cystathionine
D172_015885	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
D172_015890	ENOG4105C6K	Malic enzyme
D172_015895	ENOG4105VFB	Binds the 23S rRNA (By similarity)
D172_015900	ENOG4105C25	Primosomal protein n'
D172_015910	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
D172_015915	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
D172_015940	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
D172_015950	ENOG4105BZU	Histidine kinase
D172_015955	ENOG4105CI2	imidazolone-5-propionate hydrolase
D172_015965	ENOG4105CGP	Urocanate hydratase
D172_015970	ENOG4105C84	Histidine ammonia-lyase
D172_015975	ENOG4108535	NAD dependent epimerase/dehydratase family
D172_015980	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D172_015985	ENOG4105M6F	mutator MutT protein
D172_015995	ENOG4105C9K	Endothelin-converting enzyme 1
D172_016005	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
D172_016010	ENOG4105N42	UPF0307 protein
D172_016015	ENOG4105D4P	Coproporphyrinogen iii oxidase
D172_016020	ENOG4105XCT	Protein of unknown function (DUF2489)
D172_016030	ENOG4106RE7	Cytochrome
D172_016035	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
D172_016050	ENOG4105C2M	dna polymerase I
D172_016055	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
D172_016060	ENOG4105MPD	Cytochrome
D172_016065	ENOG4105BZU	Histidine kinase
D172_016070	ENOG4105C4R	Atp-dependent dna helicase
D172_016075	ENOG4105W0Z	cytoplasmic protein
D172_016080	ENOG4105K4T	epimerase
D172_016085	ENOG41077A9	carbonic anhydrase
D172_016100	ENOG4105C7B	Threonine dehydratase
D172_016105	ENOG4105C01	Dihydroxy-acid dehydratase
D172_016120	ENOG4105DIJ	Phosphoethanolamine transferase
D172_016125	ENOG41080IJ	Diacylglycerol kinase
D172_016130	ENOG4105E0M	Sulfatase
D172_016135	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D172_016185	ENOG4108ZT0	50S ribosomal protein l17
D172_016190	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D172_016195	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
D172_016205	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D172_016215	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
D172_016220	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
D172_016225	ENOG4105VPB	50S ribosomal protein L30
D172_016230	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
D172_016235	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
D172_016240	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
D172_016245	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
D172_016250	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
D172_016255	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D172_016260	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
D172_016265	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
D172_016300	ENOG4105QYK	bacteriophage lambda Bor protein homolog
D172_016310	ENOG4108IUW	ABC transporter
D172_016320	ENOG41080HT	Transcriptional regulator, arsr family
D172_016360	ENOG4108NIW	Leucine export protein LeuE
D172_016370	ENOG4105BZ1	(ABC) transporter
D172_016390	ENOG4105CUY	Mechanosensitive ion channel
D172_016395	ENOG4106HNH	Acyl-transferase
D172_016400	ENOG4106HNH	Acyl-transferase
D172_016405	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
D172_016410	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
D172_016415	ENOG4105C8Q	Methyl-accepting chemotaxis
D172_016440	ENOG4107YHX	fad dependent oxidoreductase
D172_016450	ENOG4105E0F	Histidine kinase
D172_016455	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D172_016460	ENOG4108RRZ	Transcription elongation factor GreB
D172_016475	ENOG4105BZM	domain protein
D172_016490	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
D172_016495	ENOG4105MJ2	Competence protein
D172_016505	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
D172_016515	ENOG4107R73	Mate efflux family protein
D172_016525	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D172_016530	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
D172_016535	ENOG4105BZU	Histidine kinase
D172_016540	ENOG4107SDU	Methyl-accepting chemotaxis
D172_016540	ENOG4107SDU	Methyl-accepting chemotaxis
D172_016545	ENOG4108V3W	Chemotaxis protein, CheW
D172_016550	ENOG4105CBS	Chea signal transduction histidine kinase
D172_016570	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
D172_016590	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
D172_016610	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
D172_016615	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
D172_016620	ENOG4105KA0	thioesterase Superfamily protein
D172_016640	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
D172_016650	ENOG4108JUA	Transcriptional regulator
D172_016660	ENOG4108YYH	Nadph-dependent fmn reductase
D172_016690	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D172_016695	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D172_016700	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D172_016705	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
D172_016710	ENOG4105EJ2	Transcriptional regulator
D172_016720	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
D172_016725	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
D172_016730	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
D172_016735	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D172_016750	ENOG4105VKU	nucleicacid-binding protein
D172_016755	ENOG4105C5H	ABC transporter
D172_016765	ENOG4105DNZ	Alpha Beta Hydrolase
D172_016770	ENOG4105YP7	UPF0270 protein
D172_016780	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D172_016805	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
D172_016810	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
D172_016815	ENOG4105D4A	Cell wall formation (By similarity)
D172_016830	ENOG4105K59	histidine triad (HIT) protein
D172_016840	ENOG4105BZU	Histidine kinase
D172_016860	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
D172_016875	ENOG4105CHM	Aminotransferase
D172_016880	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
D172_016885	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
D172_016890	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
D172_016895	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
D172_016900	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
D172_016905	ENOG4105CBC	glutamate synthase
D172_016920	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D172_016930	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
D172_016935	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D172_016940	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
D172_016945	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
D172_016965	ENOG4105D52	delta-aminolevulinic acid dehydratase
D172_016975	ENOG4105DJ9	glucan biosynthesis protein
D172_016980	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
D172_017030	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
D172_017035	ENOG4108VWS	Yaeq family
D172_017050	ENOG4108RMU	ferritin dps family protein
D172_017055	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D172_017070	ENOG4105CUG	Oligopeptidase b
D172_017075	ENOG4108M1A	Chitin-binding protein
D172_017085	ENOG4108UMN	azlc family
D172_017095	ENOG4108V06	Glutathione peroxidase
D172_017110	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D172_017145	ENOG4108YXU	transcriptional regulator AsnC family
D172_017150	ENOG4105BZU	Histidine kinase
D172_017180	ENOG4105C9Q	fumarate hydratase class II
D172_017220	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
D172_017270	ENOG4105BZU	Histidine kinase
D172_017280	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D172_017290	ENOG4105BZU	Histidine kinase
D172_017295	ENOG4105EJC	lysr family transcriptional regulator
D172_017300	ENOG4108RYK	Nad-dependent epimerase dehydratase
D172_017310	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
D172_017315	ENOG4108VYJ	response regulator receiver protein
D172_017330	ENOG4105PBD	transposase, IS3 IS911 family protein
D172_017380	ENOG4105CMM	transposase
D172_017410	ENOG4105F9F	transposase
D172_017415	ENOG4105PBD	transposase, IS3 IS911 family protein
D172_017430	ENOG4105EMU	Dehydrogenase
D172_017435	ENOG4105D64	Mechanosensitive ion channel
D172_017450	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
D172_017460	ENOG4105K56	Transcriptional regulator
D172_017465	ENOG4108ZHJ	Organic hydroperoxide resistance protein
D172_017470	ENOG41082YX	Transcriptional regulator, arsr family
D172_017475	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D172_017485	ENOG4105C8Q	Methyl-accepting chemotaxis
D172_017535	ENOG4106VK6	Flagellar motor protein
D172_017595	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D172_017605	ENOG4105CS6	Rhs element vgr protein
D172_017685	ENOG4108Z4X	TRANSCRIPTIONal
D172_017705	ENOG4108M8H	domain protein
D172_017740	ENOG4108UAJ	Transcriptional regulator
D172_017745	ENOG4105P8Q	Curli production assembly transport component CsgG
D172_017780	ENOG4107QUY	Guanine deaminase
D172_017785	ENOG4105VT2	5-hydroxyisourate hydrolase
D172_017800	ENOG4105C7W	Xanthine dehydrogenase
D172_017820	ENOG4105EN6	Membrane
D172_017830	ENOG4107QPK	)-transporter
D172_017845	ENOG410600T	transposase
D172_017910	ENOG4105XDF	Protein of unknown function (DUF1272)
D172_017925	ENOG4105C5R	Aminotransferase
D172_017930	ENOG4105HF0	Membrane
D172_017935	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D172_017940	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
D172_017945	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
D172_017950	ENOG4108R86	Transcriptional regulator
D172_017965	ENOG4105CH6	catalase
D172_017970	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
D172_017985	ENOG4105DEI	Mannitol dehydrogenase
D172_017990	ENOG4108KPW	sugar kinase
D172_018020	ENOG4105EJC	lysr family transcriptional regulator
D172_018040	ENOG4105D7K	pfkb domain protein
D172_018070	ENOG4105C26	Dehydrogenase
D172_018105	ENOG4105PBD	transposase, IS3 IS911 family protein
D172_018150	ENOG4108W6C	Dehydrogenase
D172_018155	ENOG4105CBN	LysR family transcriptional regulator
D172_018160	ENOG4105CHR	reductase
D172_018190	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
D172_018195	ENOG4108VGW	abc transporter atp-binding protein
D172_018205	ENOG4105VNH	ABC transporter solute-binding protein
D172_018215	ENOG4107QN2	dihydrolipoyl dehydrogenase
D172_018250	ENOG4105BZU	Histidine kinase
D172_018255	ENOG4105D3G	Pseudouridine synthase
D172_018260	ENOG4105C7K	acetolactate synthase
D172_018280	ENOG4107P2S	Transcriptional regulator
D172_018305	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D172_018310	ENOG4105CTX	dehydratase
D172_018315	ENOG4107QZW	Altronate oxidoreductase
D172_018320	ENOG4105CHR	reductase
D172_018325	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
D172_018330	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
D172_018335	ENOG41069H7	transport system small permease component
D172_018340	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D172_018345	ENOG4107KJX	Transcriptional regulator
D172_018355	ENOG4105E4I	Glycoside hydrolase family 28
D172_018360	ENOG4105F5H	Glycosyl Hydrolase Family 88
D172_018365	ENOG4107XII	Glycosyl Hydrolase Family 88
D172_018370	ENOG4105D2H	Uronic isomerase
D172_018375	ENOG4108UHU	Aldolase
D172_018390	ENOG4107TDE	lipolytic protein G-D-S-L family
D172_018465	ENOG4107RDJ	Sulfotransferase
D172_018475	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D172_018480	ENOG4105EQ0	Major Facilitator superfamily
D172_018490	ENOG4107YCY	Transcriptional regulator
D172_018495	ENOG4105EE0	oxidoreductase
D172_018525	ENOG4105D3R	alkyl hydroperoxide reductase
D172_018530	ENOG4108JU3	Alkyl hydroperoxide reductase
D172_018540	ENOG4105BZU	Histidine kinase
D172_018565	ENOG4108NRW	Phospholipase, patatin family
D172_018585	ENOG4105PGM	cation diffusion facilitator family transporter
D172_018590	ENOG4105BZU	Histidine kinase
D172_018600	ENOG4108N3W	hemolysin secretion protein
D172_018610	ENOG4105E0K	tonB-dependent siderophore receptor
D172_018655	ENOG4105W53	bacterioferritin-associated ferredoxin
D172_018660	ENOG4108UQY	Iron-storage protein
D172_018680	ENOG4105PGM	cation diffusion facilitator family transporter
D172_018700	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D172_018715	ENOG4107104	thymidine kinase
D172_018720	ENOG4105C5W	Aldolase
D172_018725	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
D172_018735	ENOG4107RDJ	Sulfotransferase
D172_018750	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D172_018755	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
D172_018760	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D172_018780	ENOG4108UYB	regulatoR
D172_018790	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
D172_018795	ENOG4107R11	Transcriptional regulator
D172_018845	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
D172_018850	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
D172_018855	ENOG4108I5U	Uridine phosphorylase
D172_018870	ENOG4105C37	(CBS) domain
D172_018880	ENOG4105BZS	acriflavin resistance protein
D172_018885	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
D172_018900	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
D172_018915	ENOG4108RXX	maleylacetoacetate isomerase
D172_018920	ENOG4105F1J	Homogentisate 1,2-dioxygenase
D172_018925	ENOG4107MHI	Transcriptional regulator, MarR family
D172_018935	ENOG4108KPZ	tonB-dependent Receptor
D172_018955	ENOG4105CGH	5'-nucleotidase
D172_018975	ENOG4107QXK	peptidase
D172_018995	ENOG4105DY2	Paraquat-inducible protein b
D172_019000	ENOG4105F1S	paraquat-inducible protein a
D172_019010	ENOG4105CFG	Acts as a chaperone (By similarity)
D172_019015	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D172_019020	ENOG4108Z66	YbaK ebsC protein
D172_019055	ENOG4105C8P	)-transporter
D172_019060	ENOG4107RGH	Aldehyde dehydrogenase
D172_019075	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
D172_019095	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D172_019100	ENOG4105BZU	Histidine kinase
D172_019105	ENOG4105JQN	Transcriptional regulator
D172_019110	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
D172_019120	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
D172_019125	ENOG4105CPQ	Dehydrogenase
D172_019130	ENOG4107QPN	acyl-Coa dehydrogenase
D172_019185	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
D172_019190	ENOG4105C2W	permease
D172_019195	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
D172_019200	ENOG4105C3Q	Glycosyl transferase, family 2
D172_019205	ENOG4107QW3	Sucrose phosphorylase
D172_019220	ENOG4105YK5	50S ribosomal protein L36
D172_019225	ENOG4105NRA	50s ribosomal protein l31 type b
D172_019240	ENOG4105HEI	LysR family (Transcriptional regulator
D172_019245	ENOG4105F27	Major Facilitator
D172_019250	ENOG4105CV8	reductase
D172_019285	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D172_019300	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D172_019335	ENOG4105C84	Histidine ammonia-lyase
D172_019375	ENOG4105C2D	reductase
D172_019380	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D172_019385	ENOG4105C1J	atp-dependent rna helicase
D172_019390	ENOG4105DZ0	fad dependent oxidoreductase
D172_019395	ENOG4108Z4U	Ferredoxin
D172_019405	ENOG4105BZU	Histidine kinase
D172_019420	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
D172_019425	ENOG4105C26	Dehydrogenase
D172_019460	ENOG4105C26	Dehydrogenase
D172_019470	ENOG4105C8Y	Acetylornithine aminotransferase
D172_019490	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
D172_019495	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D172_019520	ENOG4105D58	Diguanylate phosphodiesterase
D172_019525	ENOG4105DHF	Membrane
D172_019530	ENOG4105FE9	pseudouridine synthase
D172_019565	ENOG4108UT2	hemolysin iii
D172_019570	ENOG4107ZSV	Receptor
D172_019580	ENOG4107QWR	cellulase (EC 3.2.1.4)
D172_019600	ENOG4105K6V	RNA polymerase
D172_019615	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D172_019625	ENOG4105CHR	reductase
D172_019630	ENOG4105EWK	phytoene
D172_019640	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
D172_019660	ENOG4105K70	DNA-binding protein
D172_019665	ENOG4108ZP8	Acetolactate synthase small subunit
D172_019670	ENOG4105C7K	acetolactate synthase
D172_019675	ENOG4107G87	m6 family metalloprotease domain protein
D172_019680	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D172_019695	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
D172_019700	ENOG4105EWT	decarboxylase family
D172_019705	ENOG4106TD9	Diguanylate cyclase
D172_019730	ENOG4105CZH	peptidase
D172_019735	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D172_019740	ENOG4108IQK	o-acetylhomoserine
D172_019755	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
D172_019760	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
D172_019765	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
D172_019770	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
D172_019775	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
D172_019780	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D172_019785	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
D172_019790	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
D172_019800	ENOG4107SJW	iron permease, FTR1
D172_019805	ENOG4105EEQ	Na H antiporter
D172_019820	ENOG4105DVT	helicase
D172_019825	ENOG41072GX	Peptidase M22 Glycoprotease
D172_019835	ENOG4105G6Z	alkaline phosphatase
D172_019850	ENOG4105CEY	Amp-dependent synthetase and ligase
D172_019855	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
D172_019860	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
D172_019865	ENOG4107QMS	site-determining protein
D172_019870	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
D172_019875	ENOG4105VNG	YcgL domain-containing protein
D172_019880	ENOG4105CVE	Lytic murein transglycosylase
D172_019910	ENOG4108ZZ3	UPF0260 protein
D172_019930	ENOG4105BZU	Histidine kinase
D172_019955	ENOG4109015	Biopolymer transport protein exbD tolR
D172_019960	ENOG41067XB	TonB family
D172_020025	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D172_020030	ENOG4105KT5	UmuD protein
D172_020045	ENOG4105DEN	Luciferase family
D172_020050	ENOG4108NRW	Phospholipase, patatin family
D172_020060	ENOG4107QWB	Ornithine cyclodeaminase
D172_020070	ENOG4105BZG	amino acid carrier protein
D172_020105	ENOG4105MQ5	zona occludens toxin
D172_020165	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
D172_020170	ENOG4105CQB	FAD linked oxidase domain protein
D172_020180	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
D172_020185	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
D172_020190	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
D172_020205	ENOG4107QJE	Chromosome Partitioning Protein
D172_020220	ENOG4105CGY	Dna recombination protein
D172_020230	ENOG4108J1Q	
D172_020250	ENOG4105CC0	LysR family Transcriptional regulator
D172_020255	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
D172_020265	ENOG4108J1Q	
D172_020275	ENOG4105CND	Glycosyl transferase, family 2
D172_020285	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
D172_020305	ENOG4108WAV	Transcriptional regulator
D172_020330	ENOG4105IH7	synthase
D172_020335	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
D172_020340	ENOG4105EFX	secretion protein, HlyD family
D172_020350	ENOG4108YZN	class I peptide chain release factor
D172_020400	ENOG4105C1G	acyl-Coa dehydrogenase
D172_020405	ENOG41064T2	transcriptional regulator, lysR family
D172_020410	ENOG4105C09	Bile acid
D172_020415	ENOG4108RG0	uracil-dna glycosylase
D172_020440	ENOG4105QNF	Outer membrane lipoprotein
D172_020445	ENOG4108UPT	UPF0178 protein
D172_020490	ENOG4105EYH	Exonuclease
D172_020495	ENOG4107RH8	nuclease SbcCD subunit D
D172_020525	ENOG4105CDY	transcriptional regulatory protein
D172_020535	ENOG4107RET	Isocitrate lyase
D172_020545	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
D172_020560	ENOG4105WQT	MbtH domain protein
D172_020565	ENOG4105CEY	Amp-dependent synthetase and ligase
D172_020570	ENOG4105C0W	non-ribosomal peptide synthetase
D172_020575	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
D172_020580	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D172_020585	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
D172_020590	ENOG4105EHG	Permease protein
D172_020595	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
D172_020605	ENOG4108ESX	Receptor
D172_020615	ENOG4105E7W	lamb ycsf family protein
D172_020625	ENOG4105BZU	Histidine kinase
D172_020645	ENOG4108IQE	Amp-dependent synthetase and ligase
D172_020665	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D172_020670	ENOG4105DHQ	Histidine kinase
D172_020690	ENOG4105VEQ	Cold shock protein
D172_020700	ENOG4105D9N	nucleoside
D172_020705	ENOG4105DBI	uridine monophosphokinase
D172_020710	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
D172_020715	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
D172_020720	ENOG4105PBD	transposase, IS3 IS911 family protein
D172_020735	ENOG4105CMM	transposase
D172_020740	ENOG4105DP0	ferredoxin-NADP reductase
D172_020760	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
D172_020770	ENOG4105C5H	ABC transporter
D172_020860	ENOG4105DKK	Benzoate
D172_020870	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D172_020875	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D172_020890	ENOG4105CEP	NADH dehydrogenase
D172_020895	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D172_020910	ENOG4105C8Q	Methyl-accepting chemotaxis
D172_020920	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
D172_020925	ENOG4108Z9I	-acetyltransferase
D172_020935	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
D172_020945	ENOG4105CC0	LysR family Transcriptional regulator
D172_020980	ENOG4105HMI	Membrane
D172_020985	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D172_021005	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
D172_021010	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D172_021015	ENOG4105N21	Membrane
D172_021020	ENOG4105CUT	histidyl-tRNA synthetase
D172_021025	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
D172_021030	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
D172_021040	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
D172_021045	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
D172_021050	ENOG4105CFP	Peptidase U32
D172_021065	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D172_021095	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
D172_021100	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)