locus-tag	class	description
D172_000015	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D172_000030	COG2346	COG2346, Truncated hemoglobins
D172_000035	COG0408	coproporphyrinogen oxidase activity
D172_000045	COG0551	DNA topoisomerase type I activity
D172_000055	COG0758	DNA mediated transformation
D172_000075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D172_000075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D172_000080	COG0569	domain protein
D172_000105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D172_000110	COG1739	Uncharacterized protein family UPF0029
D172_000120	COG0741	lytic transglycosylase activity
D172_000125	COG1250	3-hydroxyacyl-CoA dehydrogenase
D172_000125	COG1024	Enoyl-CoA hydratase
D172_000160	COG0187	DNA topoisomerase II activity
D172_000205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D172_000220	COG1192	Involved in chromosome partitioning
D172_000225	COG1475	DNA binding
D172_000275	COG3710	Transcriptional regulator
D172_000295	COG2801	Transposase and inactivated derivatives
D172_000350	COG1943	Transposase
D172_000355	COG4191	Histidine kinase
D172_000360	COG2204	response regulator
D172_000365	COG1566	PFAM secretion protein HlyD family protein
D172_000370	COG1136	(ABC) transporter
D172_000375	COG0577	efflux transmembrane transporter activity
D172_000405	COG0110	maltose O-acetyltransferase activity
D172_000410	COG1349	DNA-binding transcription factor activity
D172_000415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D172_000425	COG0513	Belongs to the DEAD box helicase family
D172_000435	COG4771	TonB-dependent receptor
D172_000450	COG1278	Cold shock
D172_000455	COG1278	Cold shock
D172_000490	COG3291	Pkd domain containing protein
D172_000490	COG4447	cellulose binding
D172_000490	COG5520	Belongs to the glycosyl hydrolase 30 family
D172_000520	COG2832	Protein of unknown function (DUF454)
D172_000535	COG0676	glucose-6-phosphate 1-epimerase activity
D172_000545	COG3428	Bacterial PH domain
D172_000595	COG1404	Belongs to the peptidase S8 family
D172_000600	COG1770	oligopeptidase
D172_000605	COG5002	protein histidine kinase activity
D172_000605	COG0784	Response regulator, receiver
D172_000610	COG0745	RESPONSE REGULATOR receiver
D172_000630	COG1238	metal cluster binding
D172_000635	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D172_000660	COG5002	protein histidine kinase activity
D172_000660	COG2205	protein histidine kinase activity
D172_000660	COG0784	Response regulator, receiver
D172_000665	COG1944	ATP diphosphatase activity
D172_000675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D172_000680	COG3153	acetyltransferase
D172_000680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D172_000685	COG2076	Multidrug Resistance protein
D172_000710	COG1187	pseudouridine synthase activity
D172_000735	COG1011	Hydrolase
D172_000740	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D172_000755	COG0019	diaminopimelate decarboxylase activity
D172_000770	COG0400	carboxylic ester hydrolase activity
D172_000780	COG0181	hydroxymethylbilane synthase activity
D172_000785	COG2959	enzyme of heme biosynthesis
D172_000795	COG2205	protein histidine kinase activity
D172_000795	COG0784	Response regulator, receiver
D172_000805	COG4109	DRTGG domain
D172_000830	COG2354	Protein conserved in bacteria
D172_000845	COG4774	siderophore transport
D172_000850	COG0513	Belongs to the DEAD box helicase family
D172_000865	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D172_000870	COG3118	belongs to the thioredoxin family
D172_000875	COG0513	Belongs to the DEAD box helicase family
D172_000905	COG1444	tRNA N-acetyltransferase activity
D172_000910	COG0210	DNA helicase
D172_000920	COG3112	Uncharacterised protein family (UPF0231)
D172_000940	COG0717	Belongs to the dCTP deaminase family
D172_000945	COG1011	Hydrolase
D172_000950	COG0494	nUDIX hydrolase
D172_000955	COG1218	3'(2'),5'-bisphosphate nucleotidase
D172_000980	COG0606	chelatase, subunit chli
D172_000995	COG1253	flavin adenine dinucleotide binding
D172_001010	COG0835	chemotaxis
D172_001010	COG0784	Response regulator, receiver
D172_001025	COG1946	Acyl-CoA thioesterase
D172_001060	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D172_001095	COG2356	endonuclease I
D172_001100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D172_001120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D172_001145	COG2204	response regulator
D172_001150	COG3852	Histidine kinase
D172_001160	COG0174	glutamine synthetase
D172_001210	COG0456	acetyltransferase
D172_001225	COG0019	diaminopimelate decarboxylase activity
D172_001235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D172_001250	COG2885	chlorophyll binding
D172_001265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D172_001270	COG1049	propionate catabolic process, 2-methylcitrate cycle
D172_001280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D172_001335	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D172_001345	COG2186	Transcriptional regulator
D172_001350	COG1028	Short-chain dehydrogenase reductase Sdr
D172_001355	COG3734	2-keto-3-deoxy-galactonokinase
D172_001360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D172_001375	COG0673	inositol 2-dehydrogenase activity
D172_001380	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D172_001390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D172_001395	COG1028	Short-chain dehydrogenase reductase Sdr
D172_001415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D172_001435	COG1765	OsmC-like protein
D172_001450	COG0814	amino acid
D172_001455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D172_001460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D172_001465	COG2313	pseudouridylate synthase activity
D172_001470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D172_001475	COG1846	Transcriptional regulator
D172_001480	COG1902	pentaerythritol trinitrate reductase activity
D172_001485	COG0697	spore germination
D172_001490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D172_001495	COG0135	phosphoribosylanthranilate isomerase activity
D172_001505	COG2267	carboxylic ester hydrolase activity
D172_001515	COG2801	Transposase and inactivated derivatives
D172_001520	COG2963	transposase activity
D172_001535	COG1218	3'(2'),5'-bisphosphate nucleotidase
D172_001540	COG0529	Catalyzes the synthesis of activated sulfate
D172_001545	COG0471	metal ion transport
D172_001545	COG3273	potassium ion transport
D172_001550	COG2895	sulfate adenylyltransferase (ATP) activity
D172_001565	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D172_001590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D172_001595	COG0250	Participates in transcription elongation, termination and antitermination
D172_001650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D172_001650	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D172_001655	COG0346	lactoylglutathione lyase activity
D172_001680	COG3030	protein affecting phage T7 exclusion by the F plasmid
D172_001685	COG1324	tolerance protein
D172_001690	COG4232	protein-disulfide reductase activity
D172_001700	COG0511	ligase activity, forming carbon-carbon bonds
D172_001705	COG0439	Biotin carboxylase
D172_001710	COG0802	atpase or kinase
D172_001715	COG0860	N-Acetylmuramoyl-L-alanine amidase
D172_001735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D172_001740	COG0330	HflC and HflK could
D172_001745	COG0330	HflC and HflK could
D172_001755	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
D172_001780	COG4999	Histidine kinase
D172_001780	COG3850	Histidine kinase
D172_001780	COG2205	protein histidine kinase activity
D172_001780	COG3437	response regulator, receiver
D172_001825	COG4948	Mandelate Racemase Muconate Lactonizing
D172_001855	COG3618	amidohydrolase
D172_001860	COG1028	Short-chain dehydrogenase reductase Sdr
D172_001870	COG1388	LysM domain
D172_001870	COG0741	lytic transglycosylase activity
D172_001885	COG3074	FtsZ-dependent cytokinesis
D172_001890	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D172_001895	COG2824	Alkylphosphonate utilization operon protein PhnA
D172_001900	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D172_001925	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D172_001935	COG0248	Ppx GppA phosphatase
D172_001955	COG0573	inorganic phosphate transmembrane transporter activity
D172_001970	COG1392	Phosphate transport regulator
D172_001975	COG0306	phosphate transporter
D172_001980	COG0583	DNA-binding transcription factor activity
D172_001990	COG5001	Diguanylate cyclase
D172_001990	COG5002	protein histidine kinase activity
D172_002005	COG1862	Preprotein translocase
D172_002010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D172_002015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D172_002045	COG2823	Periplasmic or secreted lipoprotein
D172_002080	COG2771	luxR family
D172_002080	COG2200	EAL domain
D172_002100	COG1280	lysine exporter protein (LysE YggA)
D172_002115	COG0123	including yeast histone deacetylase and acetoin utilization protein
D172_002130	COG5001	Diguanylate cyclase
D172_002135	COG0151	Belongs to the GarS family
D172_002150	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
D172_002155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D172_002165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D172_002185	COG0742	ribosomal rna small subunit methyltransferase
D172_002190	COG0552	protein localization to endoplasmic reticulum
D172_002195	COG2884	Cell division ATP-binding protein ftsE
D172_002200	COG2177	Part of the ABC transporter FtsEX involved in
D172_002215	COG0793	Belongs to the peptidase S41A family
D172_002220	COG4942	peptidase
D172_002230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D172_002235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D172_002250	COG0840	transmembrane signaling receptor activity
D172_002265	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D172_002275	COG2267	carboxylic ester hydrolase activity
D172_002280	COG2205	protein histidine kinase activity
D172_002285	COG0745	RESPONSE REGULATOR receiver
D172_002300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D172_002310	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D172_002340	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D172_002345	COG2186	Transcriptional regulator
D172_002350	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D172_002355	COG0508	dehydrogenase complex catalyzes the overall conversion of
D172_002360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D172_002375	COG1840	ABC-type Fe3 transport system, periplasmic component
D172_002385	COG3842	ATPase activity
D172_002395	COG1438	arginine binding
D172_002405	COG0142	geranyltranstransferase activity
D172_002435	COG4946	Tricorn protease homolog
D172_002435	COG1506	peptidase
D172_002435	COG0823	Involved in the tonB-independent uptake of proteins
D172_002455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D172_002465	COG1404	Belongs to the peptidase S8 family
D172_002470	COG2081	HI0933 family
D172_002475	COG2207	Transcriptional regulator
D172_002480	COG0697	spore germination
D172_002495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D172_002525	COG1227	inorganic diphosphatase activity
D172_002535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D172_002580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D172_002585	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D172_002595	COG0564	pseudouridine synthase activity
D172_002600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D172_002605	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D172_002610	COG4999	Histidine kinase
D172_002610	COG3850	Histidine kinase
D172_002610	COG2205	protein histidine kinase activity
D172_002610	COG3437	response regulator, receiver
D172_002625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D172_002635	COG3313	Fe-S protein
D172_002655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D172_002660	COG1042	CoA-binding domain protein
D172_002660	COG0045	succinate-CoA ligase (ADP-forming) activity
D172_002660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D172_002680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D172_002685	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D172_002695	COG0762	integral membrane protein
D172_002700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D172_002705	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D172_002730	COG0189	ligase activity
D172_002735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D172_002750	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D172_002760	COG1560	Kdo2-lipid A biosynthetic process
D172_002765	COG1538	Outer membrane efflux protein
D172_002770	COG0494	nUDIX hydrolase
D172_002775	COG3151	Protein conserved in bacteria
D172_002785	COG3150	esterase
D172_002790	COG0187	DNA topoisomerase II activity
D172_002805	COG0204	Acyl-transferase
D172_002825	COG4067	protein conserved in archaea
D172_002825	COG0189	ligase activity
D172_002855	COG0514	ATP-dependent DNA helicase (RecQ)
D172_002860	COG2050	protein possibly involved in aromatic compounds catabolism
D172_002865	COG2962	Rard protein
D172_002870	COG3706	GGDEF domain
D172_002870	COG0745	RESPONSE REGULATOR receiver
D172_002875	COG3085	chromosome segregation
D172_002880	COG0583	DNA-binding transcription factor activity
D172_002890	COG1120	ATPase activity
D172_002895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D172_002905	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
D172_002910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D172_002935	COG0668	transmembrane transport
D172_002950	COG0513	Belongs to the DEAD box helicase family
D172_002970	COG0716	FMN binding
D172_002980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D172_002985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D172_002995	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D172_003030	COG3876	Protein conserved in bacteria
D172_003035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D172_003040	COG1757	Na H antiporter
D172_003080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D172_003100	COG1509	lysine 2,3-aminomutase activity
D172_003115	COG1629	transport
D172_003115	COG4774	siderophore transport
D172_003150	COG0352	thiamine-phosphate diphosphorylase activity
D172_003155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D172_003190	COG0432	Pfam Uncharacterised protein family UPF0047
D172_003200	COG0735	belongs to the Fur family
D172_003205	COG2095	MarC family integral membrane protein
D172_003255	COG2977	Belongs to the P-Pant transferase superfamily
D172_003290	COG0019	diaminopimelate decarboxylase activity
D172_003300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D172_003305	COG1136	(ABC) transporter
D172_003310	COG0577	efflux transmembrane transporter activity
D172_003315	COG2963	transposase activity
D172_003335	COG1842	Phage shock protein A
D172_003375	COG3300	MHYT domain
D172_003375	COG5001	Diguanylate cyclase
D172_003380	COG1032	radical SAM domain protein
D172_003385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D172_003390	COG2239	Acts as a magnesium transporter
D172_003395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D172_003405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D172_003415	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D172_003420	COG1137	ATPase activity
D172_003435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D172_003450	COG1127	ABC transporter
D172_003455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D172_003460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D172_003465	COG2854	intermembrane phospholipid transfer
D172_003470	COG3113	response to antibiotic
D172_003475	COG5007	Belongs to the BolA IbaG family
D172_003490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D172_003500	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D172_003510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D172_003515	COG0723	plastoquinol--plastocyanin reductase activity
D172_003520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D172_003525	COG2857	Cytochrome c1
D172_003530	COG0625	glutathione transferase activity
D172_003535	COG2969	positive regulation of protein catabolic process
D172_003540	COG2823	Periplasmic or secreted lipoprotein
D172_003545	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D172_003555	COG3107	peptidoglycan biosynthetic process
D172_003560	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D172_003580	COG2801	Transposase and inactivated derivatives
D172_003610	COG4989	oxidoreductase activity
D172_003645	COG2198	Histidine kinase
D172_003645	COG5002	protein histidine kinase activity
D172_003645	COG0784	Response regulator, receiver
D172_003650	COG0745	RESPONSE REGULATOR receiver
D172_003655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D172_003655	COG4191	Histidine kinase
D172_003680	COG5002	protein histidine kinase activity
D172_003680	COG0784	Response regulator, receiver
D172_003680	COG2205	protein histidine kinase activity
D172_003720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D172_003735	COG0006	proline dipeptidase activity
D172_003740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D172_003745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D172_003750	COG1024	Enoyl-CoA hydratase
D172_003755	COG0557	exoribonuclease II activity
D172_003760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D172_003765	COG4774	siderophore transport
D172_003860	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
D172_003870	COG1403	HNH endonuclease
D172_003875	COG2205	protein histidine kinase activity
D172_003875	COG0784	Response regulator, receiver
D172_003900	COG0625	glutathione transferase activity
D172_003915	COG2965	DNA replication, synthesis of RNA primer
D172_003930	COG1595	DNA-templated transcription, initiation
D172_003945	COG0305	Participates in initiation and elongation during chromosome replication
D172_004005	COG2927	DNA polymerase III (CHI subunit)
D172_004010	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D172_004015	COG0795	lipopolysaccharide-transporting ATPase activity
D172_004020	COG0795	lipopolysaccharide-transporting ATPase activity
D172_004060	COG2807	transmembrane transport
D172_004065	COG2207	Transcriptional regulator
D172_004070	COG4206	TonB-dependent receptor
D172_004110	COG1012	belongs to the aldehyde dehydrogenase family
D172_004115	COG2070	2-Nitropropane dioxygenase
D172_004125	COG2204	response regulator
D172_004135	COG4251	negative regulation of phosphorylation
D172_004140	COG0784	Response regulator, receiver
D172_004145	COG2205	protein histidine kinase activity
D172_004145	COG0784	Response regulator, receiver
D172_004150	COG0179	Fumarylacetoacetate (FAA) hydrolase
D172_004155	COG0667	Aldo Keto reductase
D172_004170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D172_004175	COG0840	transmembrane signaling receptor activity
D172_004210	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D172_004235	COG2205	protein histidine kinase activity
D172_004245	COG2204	response regulator
D172_004255	COG0741	lytic transglycosylase activity
D172_004270	COG0617	tRNA 3'-terminal CCA addition
D172_004275	COG2205	protein histidine kinase activity
D172_004280	COG0745	RESPONSE REGULATOR receiver
D172_004295	COG0697	spore germination
D172_004350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D172_004370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D172_004375	COG0745	RESPONSE REGULATOR receiver
D172_004395	COG0513	Belongs to the DEAD box helicase family
D172_004400	COG2199	diguanylate cyclase activity
D172_004400	COG2203	Gaf domain
D172_004410	COG0612	Peptidase, M16
D172_004415	COG1045	serine acetyltransferase
D172_004430	COG0516	GMP reductase activity
D172_004430	COG0517	IMP dehydrogenase activity
D172_004455	COG2205	protein histidine kinase activity
D172_004455	COG0784	Response regulator, receiver
D172_004475	COG0084	hydrolase, TatD family'
D172_004485	COG0560	Phosphoserine phosphatase
D172_004505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D172_004510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D172_004515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D172_004530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D172_004565	COG0454	-acetyltransferase
D172_004585	COG3283	Transcriptional regulator of aromatic amino acids metabolism
D172_004635	COG1238	metal cluster binding
D172_004640	COG1388	LysM domain
D172_004640	COG4942	peptidase
D172_004685	COG0788	formyltetrahydrofolate deformylase activity
D172_004720	COG0438	transferase activity, transferring glycosyl groups
D172_004765	COG2239	Acts as a magnesium transporter
D172_004780	COG3025	triphosphatase activity
D172_004795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D172_004795	COG0784	Response regulator, receiver
D172_004795	COG2205	protein histidine kinase activity
D172_004795	COG2198	Histidine kinase
D172_004805	COG3706	GGDEF domain
D172_004815	COG0004	ammonium transporteR
D172_004820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D172_004825	COG0840	transmembrane signaling receptor activity
D172_004835	COG0540	Belongs to the ATCase OTCase family
D172_004850	COG3227	Zinc metalloprotease (Elastase)
D172_004870	COG2211	Major facilitator Superfamily
D172_004895	COG0271	Belongs to the BolA IbaG family
D172_004910	COG1805	sodium ion transport
D172_004915	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D172_004930	COG2871	sodium ion transport
D172_004935	COG1477	protein flavinylation
D172_004940	COG2991	Protein conserved in bacteria
D172_004950	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D172_004990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D172_005005	COG3706	GGDEF domain
D172_005005	COG0745	RESPONSE REGULATOR receiver
D172_005020	COG0123	including yeast histone deacetylase and acetoin utilization protein
D172_005030	COG0488	(ABC) transporter
D172_005040	COG0646	methionine synthase
D172_005040	COG1410	methionine synthase
D172_005045	COG0646	methionine synthase
D172_005045	COG1410	methionine synthase
D172_005075	COG3237	CsbD-like
D172_005080	COG1643	Atp-dependent helicase
D172_005130	COG1064	alcohol dehydrogenase
D172_005135	COG2814	Major facilitator Superfamily
D172_005155	COG2801	Transposase and inactivated derivatives
D172_005175	COG0415	Belongs to the DNA photolyase family
D172_005180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D172_005195	COG2205	protein histidine kinase activity
D172_005200	COG0745	RESPONSE REGULATOR receiver
D172_005225	COG0784	Response regulator, receiver
D172_005225	COG2205	protein histidine kinase activity
D172_005225	COG5002	protein histidine kinase activity
D172_005235	COG0625	glutathione transferase activity
D172_005250	COG0583	DNA-binding transcription factor activity
D172_005265	COG0697	spore germination
D172_005270	COG0339	signal peptide processing
D172_005275	COG3264	Mechanosensitive ion channel
D172_005275	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D172_005290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D172_005300	COG0443	Heat shock 70 kDa protein
D172_005330	COG0739	heme binding
D172_005335	COG0179	Fumarylacetoacetate (FAA) hydrolase
D172_005350	COG3104	oligopeptide transport
D172_005360	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D172_005370	COG1215	transferase activity, transferring glycosyl groups
D172_005390	COG2194	sulfuric ester hydrolase activity
D172_005410	COG3047	cAMP biosynthetic process
D172_005425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D172_005440	COG2201	protein-glutamate methylesterase activity
D172_005450	COG0728	peptidoglycan biosynthetic process
D172_005455	COG0196	riboflavin kinase activity
D172_005470	COG1047	Peptidyl-prolyl cis-trans
D172_005480	COG0745	RESPONSE REGULATOR receiver
D172_005480	COG2972	Histidine kinase
D172_005530	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D172_005535	COG0564	pseudouridine synthase activity
D172_005545	COG0542	response to heat
D172_005550	COG0840	transmembrane signaling receptor activity
D172_005565	COG4536	flavin adenine dinucleotide binding
D172_005570	COG4137	Cytochrome C assembly protein
D172_005575	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D172_005600	COG1605	Chorismate mutase
D172_005600	COG0287	Prephenate dehydrogenase
D172_005605	COG0077	Prephenate dehydratase
D172_005605	COG1605	Chorismate mutase
D172_005615	COG0023	Translation Initiation Factor
D172_005625	COG0745	RESPONSE REGULATOR receiver
D172_005635	COG1448	Aminotransferase
D172_005640	COG0814	amino acid
D172_005650	COG2885	chlorophyll binding
D172_005705	COG0702	epimerase
D172_005715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D172_005725	COG2315	Protein conserved in bacteria
D172_005750	COG3555	Aspartyl Asparaginyl beta-hydroxylase
D172_005780	COG1404	Belongs to the peptidase S8 family
D172_005805	COG3300	MHYT domain
D172_005805	COG5001	Diguanylate cyclase
D172_005810	COG1025	Belongs to the peptidase M16 family
D172_005815	COG2062	phosphohistidine phosphatase, SixA
D172_005820	COG0251	oxidation-reduction process
D172_005825	COG1028	Short-chain dehydrogenase reductase Sdr
D172_005835	COG2840	Smr protein MutS2
D172_005840	COG2890	protein-(glutamine-N5) methyltransferase activity
D172_005875	COG3101	peptidyl-lysine hydroxylation
D172_005890	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D172_005905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D172_005925	COG0477	Major facilitator Superfamily
D172_005945	COG2801	Transposase and inactivated derivatives
D172_005985	COG0123	including yeast histone deacetylase and acetoin utilization protein
D172_005995	COG0730	response to heat
D172_006000	COG1199	ATP-dependent helicase activity
D172_006005	COG0417	DNA replication proofreading
D172_006010	COG4206	TonB-dependent receptor
D172_006030	COG1061	Type III restriction enzyme res subunit
D172_006040	COG0729	surface antigen
D172_006065	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
D172_006095	COG3098	single-species biofilm formation
D172_006100	COG0564	pseudouridine synthase activity
D172_006110	COG0741	lytic transglycosylase activity
D172_006110	COG1388	LysM domain
D172_006120	COG2226	methyltransferase
D172_006130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D172_006195	COG1960	acyl-CoA dehydrogenase activity
D172_006200	COG0121	glutamine amidotransferase
D172_006210	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D172_006245	COG1451	nucleotide metabolic process
D172_006250	COG1801	Protein of unknown function DUF72
D172_006290	COG0513	Belongs to the DEAD box helicase family
D172_006315	COG0626	cystathionine gamma-synthase activity
D172_006340	COG1960	acyl-CoA dehydrogenase activity
D172_006350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D172_006355	COG1823	symporter activity
D172_006360	COG2197	response regulator
D172_006415	COG1115	amino acid carrier protein
D172_006445	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D172_006470	COG2866	Carboxypeptidase
D172_006475	COG1115	amino acid carrier protein
D172_006485	COG3139	Protein of unknown function (DUF1315)
D172_006525	COG0210	DNA helicase
D172_006545	COG0840	transmembrane signaling receptor activity
D172_006565	COG2801	Transposase and inactivated derivatives
D172_006600	COG2801	Transposase and inactivated derivatives
D172_006605	COG2963	transposase activity
D172_006620	COG2755	lipolytic protein G-D-S-L family
D172_006625	COG4181	ATPase activity
D172_006630	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
D172_006650	COG0811	peptide transport
D172_006670	COG2885	chlorophyll binding
D172_006675	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
D172_006730	COG5002	protein histidine kinase activity
D172_006730	COG0784	Response regulator, receiver
D172_006740	COG3866	Pectate lyase
D172_006755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D172_006775	COG1902	pentaerythritol trinitrate reductase activity
D172_006795	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D172_006800	COG1074	ATP-dependent DNA helicase activity
D172_006805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D172_006830	COG0589	response to stress
D172_006835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D172_006850	COG2217	Heavy metal translocating P-type atpase
D172_006860	COG2010	Cytochrome c
D172_006875	COG3278	Belongs to the heme-copper respiratory oxidase family
D172_006905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D172_006910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D172_006915	COG2957	Belongs to the agmatine deiminase family
D172_006935	COG0583	DNA-binding transcription factor activity
D172_006955	COG4771	TonB-dependent receptor
D172_006960	COG0848	biopolymer transport protein
D172_006985	COG3083	sulfuric ester hydrolase activity
D172_006995	COG3081	Nucleoid-associated protein
D172_007000	COG1530	ribonuclease E activity
D172_007010	COG0546	phosphoglycolate phosphatase activity
D172_007020	COG1399	metal-binding, possibly nucleic acid-binding protein
D172_007035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D172_007040	COG1028	Short-chain dehydrogenase reductase Sdr
D172_007045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D172_007050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D172_007055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D172_007060	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D172_007070	COG0470	DNA polymerase III
D172_007080	COG0084	hydrolase, TatD family'
D172_007095	COG1802	Transcriptional regulator
D172_007100	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D172_007105	COG0372	Belongs to the citrate synthase family
D172_007110	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D172_007115	COG2828	Protein conserved in bacteria
D172_007155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D172_007160	COG2223	nitrite transmembrane transporter activity
D172_007165	COG2815	serine threonine protein kinase
D172_007165	COG0515	serine threonine protein kinase
D172_007175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D172_007180	COG0243	molybdopterin cofactor binding
D172_007190	COG0746	molybdenum cofactor guanylyltransferase activity
D172_007195	COG0521	Mo-molybdopterin cofactor biosynthetic process
D172_007200	COG0315	cyclic pyranopterin monophosphate synthase activity
D172_007205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D172_007210	COG0314	molybdopterin synthase activity
D172_007215	COG2258	MOSC domain
D172_007225	COG2197	response regulator
D172_007230	COG5001	Diguanylate cyclase
D172_007230	COG3300	MHYT domain
D172_007245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D172_007245	COG1648	precorrin-2 dehydrogenase activity
D172_007250	COG2146	nitrite reductase [NAD(P)H] activity
D172_007255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D172_007255	COG2146	nitrite reductase [NAD(P)H] activity
D172_007275	COG0625	glutathione transferase activity
D172_007280	COG0583	DNA-binding transcription factor activity
D172_007285	COG0589	response to stress
D172_007290	COG0659	secondary active sulfate transmembrane transporter activity
D172_007310	COG0463	Glycosyl transferase, family 2
D172_007315	COG0438	transferase activity, transferring glycosyl groups
D172_007345	COG0297	glycogen (starch) synthase activity
D172_007350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D172_007380	COG2204	response regulator
D172_007405	COG4968	Prepilin-type N-terminal cleavage methylation domain
D172_007430	COG2211	Major facilitator Superfamily
D172_007445	COG4771	TonB-dependent receptor
D172_007490	COG3693	PFAM glycoside hydrolase, family 10
D172_007495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D172_007505	COG0583	DNA-binding transcription factor activity
D172_007535	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D172_007540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D172_007545	COG2115	Belongs to the xylose isomerase family
D172_007550	COG1070	Carbohydrate kinase
D172_007560	COG3507	Belongs to the glycosyl hydrolase 43 family
D172_007565	COG1609	Transcriptional regulator
D172_007570	COG0477	Major facilitator Superfamily
D172_007590	COG4942	peptidase
D172_007610	COG0789	Transcriptional regulator
D172_007660	COG3119	arylsulfatase activity
D172_007665	COG3119	arylsulfatase activity
D172_007700	COG4771	TonB-dependent receptor
D172_007710	COG3119	arylsulfatase activity
D172_007715	COG4948	Mandelate Racemase Muconate Lactonizing
D172_007720	COG3386	PFAM SMP-30 Gluconolaconase
D172_007725	COG2814	Major facilitator Superfamily
D172_007730	COG1028	Short-chain dehydrogenase reductase Sdr
D172_007750	COG3734	2-keto-3-deoxy-galactonokinase
D172_007755	COG0800	Aldolase
D172_007760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D172_007765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D172_007815	COG0307	riboflavin synthase, alpha
D172_007845	COG1228	amidohydrolase
D172_007860	COG1278	Cold shock
D172_007865	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D172_007870	COG0542	response to heat
D172_007880	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
D172_007890	COG0492	ferredoxin-NADP+ reductase activity
D172_007895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D172_007900	COG0686	Belongs to the AlaDH PNT family
D172_007910	COG1674	ftsk spoiiie
D172_007910	COG0531	amino acid
D172_007920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D172_007975	COG2133	pyrroloquinoline quinone binding
D172_007985	COG3977	Valine--pyruvate aminotransferase
D172_007995	COG0826	peptidase U32
D172_008000	COG2205	protein histidine kinase activity
D172_008005	COG0745	RESPONSE REGULATOR receiver
D172_008020	COG3034	peptidoglycan biosynthetic process
D172_008025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D172_008030	COG1129	ABC transporter
D172_008030	COG0842	Transport permease protein
D172_008035	COG0842	Transport permease protein
D172_008050	COG2273	Hydrolase Family 16
D172_008055	COG1132	(ABC) transporter
D172_008095	COG2850	peptidyl-arginine hydroxylation
D172_008100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D172_008115	COG5001	Diguanylate cyclase
D172_008115	COG4251	negative regulation of phosphorylation
D172_008115	COG3706	GGDEF domain
D172_008115	COG2203	Gaf domain
D172_008125	COG1187	pseudouridine synthase activity
D172_008130	COG2920	part of a sulfur-relay system
D172_008140	COG2923	Belongs to the DsrF TusC family
D172_008150	COG0670	Belongs to the BI1 family
D172_008185	COG1956	GAF domain-containing protein
D172_008195	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
D172_008210	COG0308	aminopeptidase N
D172_008230	COG4447	cellulose binding
D172_008240	COG2902	Dehydrogenase
D172_008280	COG2333	competence protein COMEC
D172_008280	COG0658	competence protein
D172_008305	COG0564	pseudouridine synthase activity
D172_008310	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D172_008315	COG2166	iron-sulfur cluster assembly
D172_008320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D172_008330	COG2009	succinate dehydrogenase
D172_008335	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D172_008340	COG1053	succinate dehydrogenase
D172_008350	COG0567	Dehydrogenase, E1 component
D172_008355	COG0508	dehydrogenase complex catalyzes the overall conversion of
D172_008380	COG0735	belongs to the Fur family
D172_008400	COG0596	Alpha beta hydrolase
D172_008410	COG0033	Phosphoglucomutase
D172_008425	COG0022	dehydrogenase e1 component
D172_008455	COG4555	ABC transporter
D172_008460	COG1668	transmembrane transport
D172_008480	COG1720	tRNA m6t6A37 methyltransferase activity
D172_008525	COG3842	ATPase activity
D172_008530	COG1178	ABC-type Fe3 transport system permease component
D172_008545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D172_008560	COG2226	methyltransferase
D172_008575	COG0501	Belongs to the peptidase M48B family
D172_008595	COG2801	Transposase and inactivated derivatives
D172_008640	COG1131	(ABC) transporter
D172_008665	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D172_008700	COG0488	(ABC) transporter
D172_008705	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D172_008710	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D172_008730	COG0405	Gamma-glutamyltransferase
D172_008735	COG0281	malic enzyme
D172_008745	COG4325	translation initiation factor activity
D172_008765	COG2198	Histidine kinase
D172_008765	COG5002	protein histidine kinase activity
D172_008765	COG0784	Response regulator, receiver
D172_008805	COG2201	protein-glutamate methylesterase activity
D172_008810	COG0714	Associated with various cellular activities
D172_008825	COG2056	Na+-H+ antiporter family
D172_008830	COG1607	acyl-coa hydrolase
D172_008850	COG3130	regulation of translation
D172_008855	COG1309	transcriptional regulator
D172_008860	COG0604	alcohol dehydrogenase
D172_008865	COG4628	conserved protein (DUF2132)
D172_008920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D172_008965	COG3547	Transposase (IS116 IS110 IS902 family)
D172_008990	COG1028	Short-chain dehydrogenase reductase Sdr
D172_009000	COG1024	Enoyl-CoA hydratase
D172_009005	COG1024	Enoyl-CoA hydratase
D172_009020	COG0183	Belongs to the thiolase family
D172_009030	COG1960	acyl-CoA dehydrogenase activity
D172_009035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D172_009055	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D172_009065	COG0583	DNA-binding transcription factor activity
D172_009070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D172_009070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D172_009075	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D172_009080	COG1984	allophanate hydrolase subunit 2
D172_009095	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D172_009100	COG0367	asparagine synthase
D172_009115	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D172_009120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D172_009125	COG2176	DNA-directed DNA polymerase activity
D172_009130	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D172_009130	COG0517	IMP dehydrogenase activity
D172_009160	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D172_009175	COG0539	negative regulation of cytoplasmic translation
D172_009180	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D172_009210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D172_009220	COG1012	belongs to the aldehyde dehydrogenase family
D172_009225	COG1028	Short-chain dehydrogenase reductase Sdr
D172_009230	COG1063	alcohol dehydrogenase
D172_009245	COG3119	arylsulfatase activity
D172_009270	COG2706	6-phosphogluconolactonase activity
D172_009280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D172_009290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D172_009315	COG1085	galactose-1-phosphate uridylyltransferase
D172_009325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D172_009330	COG2814	Major facilitator Superfamily
D172_009340	COG2186	Transcriptional regulator
D172_009350	COG3119	arylsulfatase activity
D172_009360	COG2801	Transposase and inactivated derivatives
D172_009365	COG2963	transposase activity
D172_009370	COG3738	Protein conserved in bacteria
D172_009400	COG5285	phytanoyl-CoA dioxygenase
D172_009445	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
D172_009465	COG2124	cytochrome p450
D172_009470	COG4948	Mandelate Racemase Muconate Lactonizing
D172_009475	COG3386	PFAM SMP-30 Gluconolaconase
D172_009490	COG0545	Peptidyl-prolyl cis-trans isomerase
D172_009510	COG0778	Nitroreductase
D172_009520	COG0446	pyridine nucleotide-disulphide oxidoreductase
D172_009520	COG1902	pentaerythritol trinitrate reductase activity
D172_009525	COG0616	signal peptide processing
D172_009530	COG0252	asparaginase activity
D172_009535	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D172_009540	COG0469	pyruvate kinase activity
D172_009545	COG3279	Response regulator of the LytR AlgR family
D172_009550	COG2972	Histidine kinase
D172_009555	COG0659	secondary active sulfate transmembrane transporter activity
D172_009560	COG1522	sequence-specific DNA binding
D172_009595	COG0318	PFAM AMP-dependent synthetase and ligase
D172_009600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D172_009605	COG4807	Protein conserved in bacteria
D172_009610	COG4591	ABC-type transport system involved in lipoprotein release permease component
D172_009620	COG4591	ABC-type transport system involved in lipoprotein release permease component
D172_009625	COG0583	DNA-binding transcription factor activity
D172_009650	COG1285	pathogenesis
D172_009675	COG1285	pathogenesis
D172_009685	COG0189	ligase activity
D172_009690	COG2824	Alkylphosphonate utilization operon protein PhnA
D172_009700	COG2207	Transcriptional regulator
D172_009725	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D172_009730	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D172_009740	COG5265	(ABC) transporter
D172_009745	COG3590	peptidase
D172_009770	COG0800	Aldolase
D172_009780	COG1609	Transcriptional regulator
D172_009785	COG0837	glucose binding
D172_009790	COG1609	Transcriptional regulator
D172_009800	COG3279	Response regulator of the LytR AlgR family
D172_009810	COG1472	Belongs to the glycosyl hydrolase 3 family
D172_009820	COG4771	TonB-dependent receptor
D172_009840	COG0366	Alpha amylase catalytic
D172_009855	COG0366	Alpha amylase catalytic
D172_009860	COG2862	Uncharacterized protein family, UPF0114
D172_009870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D172_009880	COG1301	dicarboxylic acid transport
D172_009885	COG0616	signal peptide processing
D172_009890	COG2267	carboxylic ester hydrolase activity
D172_009895	COG1028	Short-chain dehydrogenase reductase Sdr
D172_009900	COG1187	pseudouridine synthase activity
D172_009905	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D172_009930	COG2226	methyltransferase
D172_009935	COG3092	negative regulation of chromosome organization
D172_009940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D172_009945	COG0857	belongs to the CobB CobQ family
D172_009945	COG0280	phosphate acetyltransferase
D172_009960	COG1393	Belongs to the ArsC family
D172_009970	COG1876	peptidase activity
D172_009985	COG3220	belongs to the UPF0276 family
D172_010005	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
D172_010010	COG3134	Outer membrane lipoprotein
D172_010015	COG0436	Aminotransferase
D172_010040	COG0489	protein tyrosine kinase activity
D172_010050	COG0800	Aldolase
D172_010120	COG3038	cytochrome b561
D172_010130	COG0009	L-threonylcarbamoyladenylate synthase
D172_010135	COG0613	PHP domain protein
D172_010140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D172_010145	COG0512	Glutamine amidotransferase of anthranilate synthase
D172_010155	COG0135	phosphoribosylanthranilate isomerase activity
D172_010155	COG0134	indole-3-glycerol-phosphate synthase activity
D172_010170	COG0693	protein deglycase activity
D172_010180	COG2917	probably involved in intracellular septation
D172_010190	COG0733	neurotransmitter:sodium symporter activity
D172_010195	COG2350	Protein conserved in bacteria
D172_010205	COG0745	RESPONSE REGULATOR receiver
D172_010210	COG2205	protein histidine kinase activity
D172_010225	COG0628	permease
D172_010230	COG1090	epimerase
D172_010235	COG1472	Belongs to the glycosyl hydrolase 3 family
D172_010245	COG2723	6-phospho-beta-galactosidase activity
D172_010250	COG2211	Major facilitator Superfamily
D172_010255	COG1609	Transcriptional regulator
D172_010270	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D172_010275	COG1505	serine-type exopeptidase activity
D172_010285	COG4771	TonB-dependent receptor
D172_010300	COG0543	2 iron, 2 sulfur cluster binding
D172_010300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D172_010305	COG2133	pyrroloquinoline quinone binding
D172_010325	COG0662	Cupin 2, conserved barrel domain protein
D172_010340	COG3647	Membrane
D172_010345	COG0300	oxidoreductase activity
D172_010385	COG1472	Belongs to the glycosyl hydrolase 3 family
D172_010395	COG2211	Major facilitator Superfamily
D172_010405	COG0583	DNA-binding transcription factor activity
D172_010440	COG3220	belongs to the UPF0276 family
D172_010470	COG0596	Alpha beta hydrolase
D172_010595	COG4695	Portal protein
D172_010620	COG2186	Transcriptional regulator
D172_010640	COG1598	PFAM Uncharacterised protein family UPF0150
D172_010680	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D172_010710	COG0582	viral genome integration into host DNA
D172_010715	COG2925	Exonuclease
D172_010720	COG2084	Dehydrogenase
D172_010725	COG0386	Belongs to the glutathione peroxidase family
D172_010730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D172_010735	COG0733	neurotransmitter:sodium symporter activity
D172_010745	COG0527	aspartate kinase activity
D172_010775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D172_010775	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D172_010860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D172_010870	COG0505	Belongs to the CarA family
D172_010890	COG2267	carboxylic ester hydrolase activity
D172_010900	COG2814	Major facilitator Superfamily
D172_010910	COG1420	regulation of RNA biosynthetic process
D172_010925	COG0497	DNA recombination
D172_010930	COG2199	diguanylate cyclase activity
D172_010930	COG2203	Gaf domain
D172_010935	COG0493	'glutamate synthase
D172_010940	COG0067	glutamate synthase
D172_010940	COG0069	glutamate synthase activity
D172_010940	COG0070	glutamate synthase
D172_010950	COG1136	(ABC) transporter
D172_010955	COG1136	(ABC) transporter
D172_010955	COG0577	efflux transmembrane transporter activity
D172_010960	COG0577	efflux transmembrane transporter activity
D172_010960	COG1136	(ABC) transporter
D172_010965	COG2204	response regulator
D172_010970	COG5000	phosphorelay sensor kinase activity
D172_010975	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D172_010985	COG2766	serine protein kinase
D172_010990	COG2718	Belongs to the UPF0229 family
D172_010995	COG2719	SpoVR family
D172_011000	COG0589	response to stress
D172_011010	COG2201	protein-glutamate methylesterase activity
D172_011015	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D172_011030	COG0564	pseudouridine synthase activity
D172_011060	COG3219	Protein conserved in bacteria
D172_011065	COG3220	belongs to the UPF0276 family
D172_011075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D172_011100	COG0848	biopolymer transport protein
D172_011105	COG0811	peptide transport
D172_011110	COG0811	peptide transport
D172_011120	COG1278	Cold shock
D172_011125	COG0418	dihydroorotase activity
D172_011130	COG5001	Diguanylate cyclase
D172_011130	COG4251	negative regulation of phosphorylation
D172_011130	COG2203	Gaf domain
D172_011130	COG3706	GGDEF domain
D172_011135	COG0583	DNA-binding transcription factor activity
D172_011140	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D172_011145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D172_011165	COG1228	amidohydrolase
D172_011170	COG3228	Belongs to the MtfA family
D172_011180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D172_011190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D172_011200	COG1760	l-serine dehydratase
D172_011205	COG2252	PERMEase
D172_011255	COG1418	mRNA catabolic process
D172_011270	COG3706	GGDEF domain
D172_011270	COG0745	RESPONSE REGULATOR receiver
D172_011275	COG1643	Atp-dependent helicase
D172_011280	COG1446	asparaginase
D172_011295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D172_011305	COG1104	cysteine desulfurase activity
D172_011325	COG4783	chaperone-mediated protein folding
D172_011330	COG1393	Belongs to the ArsC family
D172_011350	COG2854	intermembrane phospholipid transfer
D172_011355	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D172_011370	COG2716	regulation of RNA biosynthetic process
D172_011375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D172_011405	COG2801	Transposase and inactivated derivatives
D172_011410	COG2963	transposase activity
D172_011420	COG2226	methyltransferase
D172_011425	COG0602	queuosine metabolic process
D172_011455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D172_011465	COG0534	Mate efflux family protein
D172_011495	COG2199	diguanylate cyclase activity
D172_011495	COG2200	EAL domain
D172_011515	COG4658	electron transport chain
D172_011520	COG4659	FMN binding
D172_011525	COG4660	Part of a membrane complex involved in electron transport
D172_011530	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D172_011550	COG2963	transposase activity
D172_011555	COG2801	Transposase and inactivated derivatives
D172_011560	COG0497	DNA recombination
D172_011590	COG1982	Orn Lys Arg decarboxylase major
D172_011610	COG2801	Transposase and inactivated derivatives
D172_011640	COG0800	Aldolase
D172_011645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D172_011650	COG2271	Major facilitator Superfamily
D172_011655	COG1917	Cupin 2, conserved barrel domain protein
D172_011675	COG0346	lactoylglutathione lyase activity
D172_011680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D172_011685	COG0612	Peptidase, M16
D172_011770	COG2801	Transposase and inactivated derivatives
D172_011780	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D172_011800	COG3115	cell septum assembly
D172_011805	COG1196	nuclear chromosome segregation
D172_011810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D172_011820	COG1566	PFAM secretion protein HlyD family protein
D172_011830	COG4269	membrane
D172_011850	COG1166	arginine decarboxylase activity
D172_011855	COG1742	UPF0060 membrane protein
D172_011875	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
D172_011885	COG2363	Small membrane protein
D172_011895	COG0583	DNA-binding transcription factor activity
D172_011905	COG5505	Protein of unknown function (DUF819)
D172_011920	COG3437	response regulator, receiver
D172_011920	COG0784	Response regulator, receiver
D172_011925	COG2890	protein-(glutamine-N5) methyltransferase activity
D172_011950	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D172_011965	COG0012	GTP binding
D172_012025	COG5001	Diguanylate cyclase
D172_012025	COG3300	MHYT domain
D172_012030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D172_012040	COG1702	phosphate starvation-inducible protein PhoH
D172_012050	COG4535	Mg2 and Co2 transporter CorC
D172_012055	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D172_012100	COG0534	Mate efflux family protein
D172_012125	COG0545	Peptidyl-prolyl cis-trans isomerase
D172_012130	COG1067	ATP-dependent peptidase activity
D172_012135	COG2888	peptidyl-tyrosine sulfation
D172_012155	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D172_012160	COG0799	negative regulation of ribosome biogenesis
D172_012170	COG0768	penicillin binding
D172_012175	COG0772	Belongs to the SEDS family
D172_012180	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D172_012185	COG1686	Belongs to the peptidase S11 family
D172_012210	COG0724	RNA recognition motif
D172_012225	COG2963	transposase activity
D172_012230	COG2801	Transposase and inactivated derivatives
D172_012270	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
D172_012360	COG2212	antiporter activity
D172_012370	COG0651	ATP synthesis coupled electron transport
D172_012375	COG1006	Multisubunit Na H antiporter MnhC subunit
D172_012380	COG2111	Na H antiporter
D172_012380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D172_012420	COG0195	Participates in both transcription termination and antitermination
D172_012440	COG3046	protein related to deoxyribodipyrimidine photolyase
D172_012465	COG0450	alkyl hydroperoxide reductase
D172_012470	COG2801	Transposase and inactivated derivatives
D172_012510	COG2801	Transposase and inactivated derivatives
D172_012560	COG0037	tRNA processing
D172_012570	COG0587	DNA-directed DNA polymerase activity
D172_012590	COG1294	oxidase, subunit
D172_012595	COG4890	Cyd operon protein YbgT
D172_012605	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D172_012610	COG3866	Pectate lyase
D172_012640	COG0750	zinc metalloprotease
D172_012655	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D172_012660	COG0233	cytoplasmic translational termination
D172_012680	COG0024	Methionine aminopeptidase
D172_012715	COG0626	cystathionine gamma-synthase activity
D172_012720	COG3768	UPF0283 membrane protein
D172_012725	COG3106	COG3106 Predicted ATPase
D172_012730	COG1983	PspC domain protein
D172_012740	COG1842	Phage shock protein A
D172_012745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D172_012750	COG0747	negative chemotaxis
D172_012755	COG4168	peptide transport system, permease
D172_012760	COG4171	peptide transport system, permease
D172_012770	COG4172	Belongs to the ABC transporter superfamily
D172_012775	COG2514	catechol 2,3-dioxygenase activity
D172_012780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D172_012790	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D172_012795	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D172_012845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D172_012870	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D172_012875	COG1286	toxin biosynthetic process
D172_012885	COG0285	dihydrofolate synthase activity
D172_012915	COG1024	Enoyl-CoA hydratase
D172_012915	COG1250	3-hydroxyacyl-CoA dehydrogenase
D172_012925	COG0714	Associated with various cellular activities
D172_012940	COG2304	oxidoreductase activity
D172_012945	COG2304	oxidoreductase activity
D172_012955	COG1595	DNA-templated transcription, initiation
D172_012975	COG0519	Catalyzes the synthesis of GMP from XMP
D172_013020	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D172_013035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D172_013040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D172_013050	COG1534	Rna-binding protein
D172_013080	COG0745	RESPONSE REGULATOR receiver
D172_013085	COG2205	protein histidine kinase activity
D172_013090	COG0733	neurotransmitter:sodium symporter activity
D172_013095	COG2153	protein acetylation
D172_013100	COG4326	sporulation control protein
D172_013115	COG2205	protein histidine kinase activity
D172_013120	COG0745	RESPONSE REGULATOR receiver
D172_013135	COG3706	GGDEF domain
D172_013140	COG0583	DNA-binding transcription factor activity
D172_013150	COG0840	transmembrane signaling receptor activity
D172_013155	COG2827	Endonuclease containing a URI domain
D172_013160	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D172_013170	COG2867	negative regulation of translational initiation
D172_013180	COG4206	TonB-dependent receptor
D172_013185	COG0450	alkyl hydroperoxide reductase
D172_013195	COG2186	Transcriptional regulator
D172_013200	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D172_013215	COG1555	photosystem II stabilization
D172_013220	COG3141	response to X-ray
D172_013225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D172_013230	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D172_013235	COG2853	Lipoprotein
D172_013255	COG1138	Cytochrome C-type biogenesis protein
D172_013265	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D172_013270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D172_013275	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D172_013280	COG4133	protoheme IX ABC transporter activity
D172_013300	COG0835	chemotaxis
D172_013310	COG1192	Involved in chromosome partitioning
D172_013315	COG1360	Flagellar Motor Protein
D172_013320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D172_013330	COG2198	Histidine kinase
D172_013330	COG0643	Histidine kinase
D172_013335	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
D172_013350	COG0455	bacterial-type flagellum organization
D172_013360	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D172_013375	COG1987	bacterial-type flagellum assembly
D172_013385	COG3190	flagellar
D172_013400	COG1580	Controls the rotational direction of flagella during chemotaxis
D172_013405	COG3144	bacterial-type flagellum assembly
D172_013425	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D172_013435	COG1677	Flagellar hook-basal body complex protein FliE
D172_013440	COG2204	response regulator
D172_013445	COG3852	Histidine kinase
D172_013450	COG0519	Catalyzes the synthesis of GMP from XMP
D172_013455	COG2204	response regulator
D172_013470	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D172_013475	COG1334	flagellar protein FlaG
D172_013500	COG1256	bacterial-type flagellum assembly
D172_013505	COG3951	Flagellar rod assembly protein muramidase FlgJ
D172_013505	COG1705	Flagellar rod assembly protein muramidase FlgJ
D172_013520	COG4786	Flagellar basal body rod
D172_013525	COG4787	bacterial-type flagellum-dependent cell motility
D172_013540	COG1558	bacterial-type flagellum-dependent cell motility
D172_013545	COG1815	bacterial-type flagellum-dependent cell motility
D172_013550	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D172_013555	COG0784	Response regulator, receiver
D172_013555	COG0835	chemotaxis
D172_013590	COG0678	peroxiredoxin activity
D172_013590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D172_013655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D172_013670	COG0730	response to heat
D172_013675	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
D172_013685	COG3066	DNA modification
D172_013700	COG3956	TIGRFAM MazG family protein
D172_013705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D172_013715	COG4999	Histidine kinase
D172_013715	COG3850	Histidine kinase
D172_013715	COG2205	protein histidine kinase activity
D172_013715	COG3437	response regulator, receiver
D172_013740	COG0681	Belongs to the peptidase S26 family
D172_013765	COG1595	DNA-templated transcription, initiation
D172_013770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D172_013780	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D172_013785	COG0354	folic acid binding
D172_013790	COG1047	Peptidyl-prolyl cis-trans
D172_013805	COG3099	Belongs to the UPF0263 family
D172_013810	COG1024	Enoyl-CoA hydratase
D172_013810	COG1250	3-hydroxyacyl-CoA dehydrogenase
D172_013820	COG1346	cytolysis
D172_013825	COG0668	transmembrane transport
D172_013850	COG3267	Type II secretory pathway component ExeA
D172_013850	COG3409	Peptidoglycan-binding domain 1 protein
D172_013880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D172_013890	COG4206	TonB-dependent receptor
D172_013910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D172_013910	COG0301	tRNA thio-modification
D172_013955	COG0165	Argininosuccinate lyase
D172_013955	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D172_013970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D172_013975	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D172_013985	COG0076	glutamate decarboxylase activity
D172_013990	COG2200	EAL domain
D172_013990	COG3287	FIST C domain
D172_013990	COG2199	diguanylate cyclase activity
D172_013995	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D172_014000	COG0842	Transport permease protein
D172_014005	COG1131	(ABC) transporter
D172_014010	COG0163	prenyltransferase activity
D172_014015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D172_014025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D172_014060	COG0583	DNA-binding transcription factor activity
D172_014115	COG2963	transposase activity
D172_014120	COG2801	Transposase and inactivated derivatives
D172_014130	COG1580	Controls the rotational direction of flagella during chemotaxis
D172_014135	COG0705	Rhomboid family
D172_014155	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D172_014160	COG0859	PFAM glycosyl transferase family 9
D172_014165	COG3642	lipopolysaccharide core region biosynthetic process
D172_014190	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D172_014195	COG1519	Transferase
D172_014205	COG3784	Protein of unknown function (DUF1318)
D172_014230	COG0590	tRNA wobble adenosine to inosine editing
D172_014235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D172_014270	COG3118	belongs to the thioredoxin family
D172_014275	COG1473	amidohydrolase
D172_014280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D172_014295	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D172_014305	COG0142	geranyltranstransferase activity
D172_014315	COG3706	GGDEF domain
D172_014320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D172_014350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D172_014350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D172_014365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D172_014380	COG2201	protein-glutamate methylesterase activity
D172_014385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D172_014385	COG4191	Histidine kinase
D172_014410	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D172_014425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D172_014450	COG5002	protein histidine kinase activity
D172_014455	COG0745	RESPONSE REGULATOR receiver
D172_014475	COG5001	Diguanylate cyclase
D172_014495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D172_014505	COG2198	Histidine kinase
D172_014505	COG2205	protein histidine kinase activity
D172_014505	COG0784	Response regulator, receiver
D172_014530	COG2199	diguanylate cyclase activity
D172_014550	COG1477	protein flavinylation
D172_014590	COG3250	beta-galactosidase activity
D172_014595	COG2259	Doxx family
D172_014600	COG1979	alcohol dehydrogenase
D172_014605	COG2207	Transcriptional regulator
D172_014655	COG1051	belongs to the nudix hydrolase family
D172_014685	COG2801	Transposase and inactivated derivatives
D172_014695	COG1668	transmembrane transport
D172_014700	COG4555	ABC transporter
D172_014710	COG2188	Transcriptional regulator
D172_014715	COG1131	(ABC) transporter
D172_014740	COG4771	TonB-dependent receptor
D172_014745	COG1858	cytochrome C peroxidase
D172_014755	COG1902	pentaerythritol trinitrate reductase activity
D172_014765	COG3791	Glutathione-dependent formaldehyde-activating
D172_014770	COG0753	catalase activity
D172_014775	COG0668	transmembrane transport
D172_014785	COG0754	glutathionylspermidine amidase activity
D172_014795	COG0783	Belongs to the Dps family
D172_014815	COG2197	response regulator
D172_014820	COG4585	Histidine kinase
D172_014830	COG0584	glycerophosphoryl diester phosphodiesterase
D172_014840	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D172_014850	COG2205	protein histidine kinase activity
D172_014855	COG1247	-acetyltransferase
D172_014895	COG3954	Phosphoribulokinase
D172_014900	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
D172_014905	COG1011	Hydrolase
D172_014920	COG0849	cell division
D172_014925	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D172_014960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D172_014965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D172_014970	COG0768	penicillin binding
D172_014975	COG3116	cell division
D172_015005	COG0435	Glutathione S-transferase
D172_015010	COG1741	Belongs to the pirin family
D172_015020	COG1295	ribonuclease BN
D172_015060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D172_015075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D172_015080	COG3128	pkhd-type hydroxylase
D172_015085	COG4774	siderophore transport
D172_015100	COG0811	peptide transport
D172_015105	COG0848	biopolymer transport protein
D172_015120	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D172_015125	COG1187	pseudouridine synthase activity
D172_015155	COG2897	thiosulfate sulfurtransferase activity
D172_015160	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D172_015180	COG5001	Diguanylate cyclase
D172_015180	COG3300	MHYT domain
D172_015190	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D172_015195	COG4181	ATPase activity
D172_015215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D172_015220	COG0678	peroxiredoxin activity
D172_015220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D172_015235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D172_015260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D172_015300	COG2089	acid synthase
D172_015310	COG1028	Short-chain dehydrogenase reductase Sdr
D172_015315	COG0667	Aldo Keto reductase
D172_015320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D172_015325	COG1086	Polysaccharide biosynthesis protein
D172_015335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D172_015340	COG1596	polysaccharide export
D172_015355	COG0438	transferase activity, transferring glycosyl groups
D172_015375	COG0110	maltose O-acetyltransferase activity
D172_015400	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D172_015410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D172_015425	COG3137	Salt-induced outer membrane protein
D172_015430	COG0668	transmembrane transport
D172_015455	COG1234	tRNA 3'-trailer cleavage
D172_015465	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D172_015490	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D172_015500	COG0822	iron-sulfur transferase activity
D172_015515	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
D172_015520	COG1609	Transcriptional regulator
D172_015530	COG1621	beta-fructofuranosidase activity
D172_015535	COG0477	Major facilitator Superfamily
D172_015545	COG4206	TonB-dependent receptor
D172_015545	COG1629	transport
D172_015555	COG0745	RESPONSE REGULATOR receiver
D172_015560	COG0339	signal peptide processing
D172_015570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D172_015715	COG0312	modulator of DNA gyrase
D172_015720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D172_015725	COG3164	Protein of unknown function
D172_015730	COG1530	ribonuclease E activity
D172_015740	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D172_015745	COG1792	Involved in formation and maintenance of cell shape
D172_015750	COG1077	Cell shape determining protein MreB Mrl
D172_015760	COG2515	1-aminocyclopropane-1-carboxylate deaminase
D172_015770	COG0784	Response regulator, receiver
D172_015770	COG2205	protein histidine kinase activity
D172_015775	COG0629	single-stranded DNA binding
D172_015780	COG2814	Major facilitator Superfamily
D172_015785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D172_015790	COG0745	RESPONSE REGULATOR receiver
D172_015805	COG0180	Tryptophanyl-tRNA synthetase
D172_015815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D172_015825	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D172_015830	COG3266	domain, Protein
D172_015870	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D172_015875	COG0527	aspartate kinase activity
D172_015875	COG0460	homoserine dehydrogenase
D172_015880	COG0626	cystathionine gamma-synthase activity
D172_015890	COG0281	malic enzyme
D172_015900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D172_015935	COG0671	phosphoesterase, PA-phosphatase related
D172_015975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D172_015985	COG0494	nUDIX hydrolase
D172_015995	COG3590	peptidase
D172_016005	COG0312	modulator of DNA gyrase
D172_016015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D172_016050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D172_016050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D172_016055	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
D172_016080	COG0702	epimerase
D172_016085	COG0288	reversible hydration of carbon dioxide
D172_016120	COG2194	sulfuric ester hydrolase activity
D172_016125	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D172_016130	COG1368	sulfuric ester hydrolase activity
D172_016135	COG0745	RESPONSE REGULATOR receiver
D172_016215	COG0201	protein transport
D172_016310	COG4555	ABC transporter
D172_016320	COG0640	Transcriptional regulator
D172_016370	COG1132	(ABC) transporter
D172_016390	COG0668	transmembrane transport
D172_016395	COG0204	Acyl-transferase
D172_016400	COG0204	Acyl-transferase
D172_016405	COG1166	arginine decarboxylase activity
D172_016410	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D172_016430	COG1082	Xylose isomerase domain protein TIM barrel
D172_016440	COG0644	oxidoreductase
D172_016450	COG2205	protein histidine kinase activity
D172_016455	COG0745	RESPONSE REGULATOR receiver
D172_016460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D172_016475	COG2183	response to ionizing radiation
D172_016495	COG1040	competence protein
D172_016515	COG0534	Mate efflux family protein
D172_016520	COG0726	polysaccharide deacetylase
D172_016530	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D172_016545	COG0835	chemotaxis
D172_016550	COG0643	Histidine kinase
D172_016550	COG2198	Histidine kinase
D172_016595	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
D172_016610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D172_016615	COG3291	Pkd domain containing protein
D172_016640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D172_016640	COG1017	nitric oxide dioxygenase activity
D172_016650	COG3604	Transcriptional regulator
D172_016655	COG0583	DNA-binding transcription factor activity
D172_016660	COG0431	NADPH-dependent FMN reductase
D172_016705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D172_016720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D172_016730	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
D172_016735	COG0545	Peptidyl-prolyl cis-trans isomerase
D172_016750	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
D172_016755	COG0488	(ABC) transporter
D172_016765	COG0429	hydrolase of the alpha beta-hydrolase fold
D172_016770	COG3089	Belongs to the UPF0270 family
D172_016830	COG0537	adenosine 5'-monophosphoramidase activity
D172_016875	COG0436	Aminotransferase
D172_016885	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
D172_016895	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D172_016900	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D172_016905	COG0069	glutamate synthase activity
D172_016940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D172_016945	COG0805	protein transport
D172_016960	COG4251	negative regulation of phosphorylation
D172_016960	COG3706	GGDEF domain
D172_016960	COG5001	Diguanylate cyclase
D172_016960	COG2203	Gaf domain
D172_016975	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
D172_016980	COG3416	Protein conserved in bacteria
D172_016980	COG2943	transferase activity, transferring hexosyl groups
D172_017035	COG4681	YaeQ
D172_017050	COG0783	Belongs to the Dps family
D172_017055	COG4206	TonB-dependent receptor
D172_017070	COG1770	oligopeptidase
D172_017075	COG3397	chitin binding
D172_017085	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D172_017095	COG0386	Belongs to the glutathione peroxidase family
D172_017110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D172_017135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D172_017145	COG1522	sequence-specific DNA binding
D172_017150	COG2205	protein histidine kinase activity
D172_017150	COG4999	Histidine kinase
D172_017150	COG3850	Histidine kinase
D172_017150	COG3437	response regulator, receiver
D172_017220	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D172_017295	COG0583	DNA-binding transcription factor activity
D172_017300	COG2910	NAD(P)H-binding
D172_017310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D172_017315	COG0745	RESPONSE REGULATOR receiver
D172_017325	COG2801	Transposase and inactivated derivatives
D172_017330	COG2963	transposase activity
D172_017380	COG2801	Transposase and inactivated derivatives
D172_017410	COG2826	transposase and inactivated derivatives, IS30 family
D172_017415	COG2963	transposase activity
D172_017430	COG4221	oxidoreductase activity
D172_017435	COG0668	transmembrane transport
D172_017445	COG2133	pyrroloquinoline quinone binding
D172_017460	COG1846	Transcriptional regulator
D172_017465	COG1764	response to oxidative stress
D172_017470	COG0640	Transcriptional regulator
D172_017475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D172_017485	COG0840	transmembrane signaling receptor activity
D172_017605	COG3501	Rhs element vgr protein
D172_017685	COG0789	Transcriptional regulator
D172_017705	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D172_017745	COG1462	curli production assembly transport component CsgG
D172_017780	COG0402	S-adenosylhomocysteine deaminase activity
D172_017785	COG2351	hydroxyisourate hydrolase activity
D172_017800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D172_017820	COG2860	membrane
D172_017830	COG0471	metal ion transport
D172_017845	COG5433	transposase activity
D172_017865	COG3547	Transposase (IS116 IS110 IS902 family)
D172_017910	COG3813	Protein conserved in bacteria
D172_017925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D172_017930	COG0730	response to heat
D172_017940	COG0154	amidase activity
D172_017945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D172_017950	COG1309	transcriptional regulator
D172_017965	COG0753	catalase activity
D172_017970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D172_017985	COG0246	Mannitol dehydrogenase
D172_017990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D172_017995	COG1966	Carbon starvation protein
D172_018040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D172_018060	COG1609	Transcriptional regulator
D172_018070	COG1012	belongs to the aldehyde dehydrogenase family
D172_018105	COG2963	transposase activity
D172_018110	COG2801	Transposase and inactivated derivatives
D172_018150	COG0300	oxidoreductase activity
D172_018155	COG0583	DNA-binding transcription factor activity
D172_018160	COG1028	Short-chain dehydrogenase reductase Sdr
D172_018190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D172_018195	COG4136	ATPase activity
D172_018205	COG4134	Bacterial extracellular solute-binding protein
D172_018250	COG0745	RESPONSE REGULATOR receiver
D172_018250	COG3706	GGDEF domain
D172_018255	COG0564	pseudouridine synthase activity
D172_018260	COG0028	Belongs to the TPP enzyme family
D172_018280	COG1609	Transcriptional regulator
D172_018290	COG1280	lysine exporter protein (LysE YggA)
D172_018305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D172_018310	COG2721	sulfolactate sulfo-lyase activity
D172_018315	COG0246	Mannitol dehydrogenase
D172_018320	COG1028	Short-chain dehydrogenase reductase Sdr
D172_018325	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D172_018335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D172_018345	COG1609	Transcriptional regulator
D172_018360	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D172_018365	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D172_018370	COG1904	glucuronate isomerase
D172_018375	COG0800	Aldolase
D172_018390	COG2755	lipolytic protein G-D-S-L family
D172_018410	COG4974	Belongs to the 'phage' integrase family
D172_018415	COG0517	IMP dehydrogenase activity
D172_018465	COG0457	Tetratricopeptide repeat
D172_018470	COG4771	TonB-dependent receptor
D172_018475	COG1902	pentaerythritol trinitrate reductase activity
D172_018480	COG2814	Major facilitator Superfamily
D172_018490	COG2186	Transcriptional regulator
D172_018495	COG0673	inositol 2-dehydrogenase activity
D172_018525	COG0450	alkyl hydroperoxide reductase
D172_018530	COG3634	alkyl hydroperoxide reductase activity
D172_018540	COG0784	Response regulator, receiver
D172_018540	COG2205	protein histidine kinase activity
D172_018565	COG4667	esterase of the alpha-beta hydrolase superfamily
D172_018600	COG0840	transmembrane signaling receptor activity
D172_018610	COG4774	siderophore transport
D172_018615	COG2119	membrane
D172_018655	COG2906	2 iron, 2 sulfur cluster binding
D172_018660	COG2193	ferroxidase activity
D172_018665	COG2193	ferroxidase activity
D172_018720	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D172_018735	COG0457	Tetratricopeptide repeat
D172_018750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D172_018755	COG0346	lactoylglutathione lyase activity
D172_018780	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
D172_018790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D172_018795	COG0583	DNA-binding transcription factor activity
D172_018855	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
D172_018860	COG0010	Belongs to the arginase family
D172_018870	COG1253	flavin adenine dinucleotide binding
D172_018895	COG1803	Methylglyoxal synthase
D172_018895	COG1597	lipid kinase activity
D172_018900	COG4628	conserved protein (DUF2132)
D172_018915	COG0625	glutathione transferase activity
D172_018920	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
D172_018995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D172_018995	COG3008	intermembrane lipid transfer
D172_019000	COG2995	paraquat-inducible protein a
D172_019040	COG4191	Histidine kinase
D172_019045	COG2204	response regulator
D172_019055	COG0471	metal ion transport
D172_019075	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D172_019080	COG2068	MobA-Related Protein
D172_019095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D172_019100	COG2199	diguanylate cyclase activity
D172_019110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D172_019125	COG1063	alcohol dehydrogenase
D172_019140	COG4974	Belongs to the 'phage' integrase family
D172_019145	COG0517	IMP dehydrogenase activity
D172_019195	COG3769	mannosylglycerate metabolic process
D172_019200	COG1215	transferase activity, transferring glycosyl groups
D172_019205	COG0366	Alpha amylase catalytic
D172_019225	COG0254	rRNA binding
D172_019240	COG0583	DNA-binding transcription factor activity
D172_019245	COG2814	Major facilitator Superfamily
D172_019250	COG0656	L-ascorbic acid biosynthetic process
D172_019285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D172_019300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D172_019305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D172_019375	COG1028	Short-chain dehydrogenase reductase Sdr
D172_019380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D172_019385	COG0513	Belongs to the DEAD box helicase family
D172_019390	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
D172_019395	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D172_019405	COG3300	MHYT domain
D172_019405	COG5001	Diguanylate cyclase
D172_019425	COG1012	belongs to the aldehyde dehydrogenase family
D172_019470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D172_019475	COG1522	sequence-specific DNA binding
D172_019490	COG1640	4-alpha-glucanotransferase
D172_019495	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D172_019505	COG0058	SHG alpha-glucan phosphorylase activity
D172_019520	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D172_019525	COG2311	Membrane
D172_019530	COG1187	pseudouridine synthase activity
D172_019535	COG0653	protein targeting
D172_019565	COG1272	protein, Hemolysin III
D172_019570	COG4771	TonB-dependent receptor
D172_019580	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D172_019600	COG1595	DNA-templated transcription, initiation
D172_019615	COG0415	Belongs to the DNA photolyase family
D172_019630	COG1233	COG1233 Phytoene dehydrogenase and related
D172_019640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D172_019660	COG0776	regulation of translation
D172_019665	COG0440	acetolactate synthase activity
D172_019670	COG0028	Belongs to the TPP enzyme family
D172_019675	COG3291	Pkd domain containing protein
D172_019675	COG4412	M6 family metalloprotease domain protein
D172_019680	COG0473	3-isopropylmalate dehydrogenase activity
D172_019700	COG1611	Belongs to the LOG family
D172_019705	COG3706	GGDEF domain
D172_019730	COG3591	Belongs to the peptidase S1B family
D172_019730	COG4990	cell redox homeostasis
D172_019735	COG0653	protein targeting
D172_019740	COG2873	o-acetylhomoserine
D172_019755	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D172_019755	COG0140	phosphoribosyl-ATP diphosphatase activity
D172_019770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D172_019775	COG0131	Imidazoleglycerol-phosphate dehydratase
D172_019775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D172_019780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D172_019790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D172_019800	COG0672	)-iron permease
D172_019820	COG1199	ATP-dependent helicase activity
D172_019825	COG1214	PFAM Peptidase M22, glycoprotease
D172_019835	COG1785	Belongs to the alkaline phosphatase family
D172_019850	COG0318	PFAM AMP-dependent synthetase and ligase
D172_019855	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
D172_019865	COG2894	cell division
D172_019880	COG2951	lytic endotransglycosylase activity
D172_019910	COG2983	Belongs to the UPF0260 family
D172_019930	COG0745	RESPONSE REGULATOR receiver
D172_019930	COG3706	GGDEF domain
D172_019945	COG0811	peptide transport
D172_019950	COG0811	peptide transport
D172_019955	COG0848	biopolymer transport protein
D172_019960	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
D172_020010	COG4895	conserved protein (DUF2196)
D172_020030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D172_020045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D172_020050	COG4667	esterase of the alpha-beta hydrolase superfamily
D172_020060	COG2423	ornithine cyclodeaminase activity
D172_020070	COG1115	amino acid carrier protein
D172_020105	COG4128	Pfam Zonular occludens toxin
D172_020165	COG3263	regulation of cellular component size
D172_020170	COG0247	lactate metabolic process
D172_020170	COG0277	FAD linked oxidase domain protein
D172_020180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D172_020180	COG0574	Belongs to the PEP-utilizing enzyme family
D172_020190	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
D172_020205	COG1192	Involved in chromosome partitioning
D172_020215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D172_020220	COG1322	Protein conserved in bacteria
D172_020230	COG2801	Transposase and inactivated derivatives
D172_020250	COG0583	DNA-binding transcription factor activity
D172_020255	COG3384	dioxygenase
D172_020265	COG2801	Transposase and inactivated derivatives
D172_020285	COG0492	ferredoxin-NADP+ reductase activity
D172_020305	COG0583	DNA-binding transcription factor activity
D172_020340	COG1566	PFAM secretion protein HlyD family protein
D172_020395	COG0300	oxidoreductase activity
D172_020400	COG1960	acyl-CoA dehydrogenase activity
D172_020405	COG0583	DNA-binding transcription factor activity
D172_020410	COG0385	Bile acid
D172_020415	COG1573	uracil-dna glycosylase
D172_020440	COG3040	lipid binding
D172_020495	COG0420	3'-5' exonuclease activity
D172_020550	COG1169	isochorismate synthase
D172_020560	COG3251	PFAM MbtH domain protein
D172_020565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D172_020570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D172_020575	COG1021	2,3-dihydroxybenzoate-AMP ligase
D172_020585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D172_020590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D172_020605	COG4774	siderophore transport
D172_020615	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D172_020625	COG3706	GGDEF domain
D172_020645	COG1022	Amp-dependent synthetase and ligase
D172_020665	COG0745	RESPONSE REGULATOR receiver
D172_020670	COG0642	Histidine kinase
D172_020690	COG1278	Cold shock
D172_020700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D172_020705	COG0572	uridine kinase
D172_020720	COG2963	transposase activity
D172_020725	COG2801	Transposase and inactivated derivatives
D172_020735	COG2801	Transposase and inactivated derivatives
D172_020740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D172_020760	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
D172_020770	COG0488	(ABC) transporter
D172_020860	COG3135	benzoate transporter
D172_020890	COG1252	NADH dehydrogenase
D172_020895	COG0514	ATP-dependent DNA helicase (RecQ)
D172_020910	COG0840	transmembrane signaling receptor activity
D172_020920	COG2130	NADP-dependent
D172_020925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D172_020945	COG0583	DNA-binding transcription factor activity
D172_020975	COG0583	DNA-binding transcription factor activity
D172_020980	COG2855	membrane
D172_020985	COG0415	Belongs to the DNA photolyase family
D172_021010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D172_021015	COG2976	Protein conserved in bacteria
D172_021030	COG1426	Protein conserved in bacteria
D172_021065	COG4206	TonB-dependent receptor
D172_021095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D172_021100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP