locus-tag	class	description
Daes_0001	COG1192	Involved in chromosome partitioning
Daes_0003	COG1475	DNA binding
Daes_0005	COG0205	6-phosphofructokinase activity
Daes_0008	COG2226	methyltransferase
Daes_0011	COG0482	sulfurtransferase activity
Daes_0012	COG1691	(AIR) carboxylase
Daes_0013	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Daes_0015	COG1136	(ABC) transporter
Daes_0015	COG0577	efflux transmembrane transporter activity
Daes_0023	COG3437	response regulator, receiver
Daes_0023	COG0784	Response regulator, receiver
Daes_0026	COG3706	GGDEF domain
Daes_0026	COG0745	RESPONSE REGULATOR receiver
Daes_0028	COG1215	transferase activity, transferring glycosyl groups
Daes_0029	COG2205	protein histidine kinase activity
Daes_0029	COG3437	response regulator, receiver
Daes_0029	COG4999	Histidine kinase
Daes_0029	COG3850	Histidine kinase
Daes_0031	COG2202	Pas domain
Daes_0031	COG2205	protein histidine kinase activity
Daes_0033	COG0784	Response regulator, receiver
Daes_0033	COG5002	protein histidine kinase activity
Daes_0033	COG2198	Histidine kinase
Daes_0034	COG1151	hydroxylamine reductase activity
Daes_0036	COG2770	Histidine kinase
Daes_0036	COG3437	response regulator, receiver
Daes_0038	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Daes_0039	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Daes_0042	COG0440	acetolactate synthase activity
Daes_0043	COG0280	phosphate acetyltransferase
Daes_0044	COG3426	butyrate kinase activity
Daes_0050	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Daes_0051	COG1704	LemA family
Daes_0055	COG0583	DNA-binding transcription factor activity
Daes_0056	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Daes_0058	COG0114	fumarate hydratase activity
Daes_0062	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Daes_0064	COG0745	RESPONSE REGULATOR receiver
Daes_0065	COG5002	protein histidine kinase activity
Daes_0067	COG0659	secondary active sulfate transmembrane transporter activity
Daes_0071	COG0415	Belongs to the DNA photolyase family
Daes_0073	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Daes_0076	COG3959	Transketolase, thiamine diphosphate binding domain
Daes_0077	COG3958	Transketolase
Daes_0078	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Daes_0080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Daes_0082	COG0398	Pfam SNARE associated Golgi protein
Daes_0085	COG2703	oxygen carrier activity
Daes_0088	COG2226	methyltransferase
Daes_0089	COG1216	Glycosyl transferase, family 2
Daes_0090	COG1215	transferase activity, transferring glycosyl groups
Daes_0098	COG1083	cytidylyl-transferase
Daes_0100	COG1216	Glycosyl transferase, family 2
Daes_0102	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Daes_0103	COG1088	dTDP-glucose 4,6-dehydratase activity
Daes_0105	COG1083	cytidylyl-transferase
Daes_0106	COG1215	transferase activity, transferring glycosyl groups
Daes_0107	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Daes_0110	COG3437	response regulator, receiver
Daes_0110	COG3850	Histidine kinase
Daes_0110	COG2205	protein histidine kinase activity
Daes_0110	COG4999	Histidine kinase
Daes_0111	COG3676	manually curated
Daes_0113	COG0840	transmembrane signaling receptor activity
Daes_0114	COG2205	protein histidine kinase activity
Daes_0114	COG0784	Response regulator, receiver
Daes_0116	COG2204	response regulator
Daes_0117	COG4191	Histidine kinase
Daes_0118	COG0745	RESPONSE REGULATOR receiver
Daes_0119	COG3848	Pyruvate phosphate dikinase
Daes_0119	COG0574	Belongs to the PEP-utilizing enzyme family
Daes_0121	COG0589	response to stress
Daes_0123	COG0730	response to heat
Daes_0127	COG0745	RESPONSE REGULATOR receiver
Daes_0128	COG3848	Pyruvate phosphate dikinase
Daes_0128	COG0574	Belongs to the PEP-utilizing enzyme family
Daes_0129	COG3676	manually curated
Daes_0130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Daes_0132	COG2813	Specifically methylates the guanine in position
Daes_0141	COG2884	Cell division ATP-binding protein ftsE
Daes_0142	COG2183	response to ionizing radiation
Daes_0145	COG5000	phosphorelay sensor kinase activity
Daes_0146	COG1090	epimerase
Daes_0147	COG2204	response regulator
Daes_0148	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Daes_0149	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Daes_0154	COG0517	IMP dehydrogenase activity
Daes_0160	COG0437	4 iron, 4 sulfur cluster binding
Daes_0165	COG0303	'Molybdopterin
Daes_0166	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Daes_0167	COG1763	Mo-molybdopterin cofactor biosynthetic process
Daes_0168	COG0746	molybdenum cofactor guanylyltransferase activity
Daes_0169	COG1073	alpha beta
Daes_0175	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Daes_0175	COG0731	radical SAM domain protein
Daes_0176	COG1530	ribonuclease E activity
Daes_0177	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Daes_0179	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Daes_0181	COG0328	RNA-DNA hybrid ribonuclease activity
Daes_0185	COG1136	(ABC) transporter
Daes_0185	COG0577	efflux transmembrane transporter activity
Daes_0186	COG4591	ABC-type transport system involved in lipoprotein release permease component
Daes_0186	COG1136	(ABC) transporter
Daes_0189	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Daes_0190	COG0330	HflC and HflK could
Daes_0191	COG0330	HflC and HflK could
Daes_0193	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Daes_0199	COG0438	transferase activity, transferring glycosyl groups
Daes_0200	COG0045	succinate-CoA ligase (ADP-forming) activity
Daes_0200	COG1042	CoA-binding domain protein
Daes_0200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Daes_0202	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Daes_0203	COG0835	chemotaxis
Daes_0205	COG1228	amidohydrolase
Daes_0206	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Daes_0207	COG1830	Aldolase
Daes_0219	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Daes_0223	COG1705	Flagellar rod assembly protein muramidase FlgJ
Daes_0223	COG1388	LysM domain
Daes_0224	COG0084	hydrolase, TatD family'
Daes_0229	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Daes_0234	COG0242	peptide deformylase activity
Daes_0235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Daes_0236	COG0124	histidyl-tRNA synthetase
Daes_0237	COG3383	formate dehydrogenase (NAD+) activity
Daes_0239	COG4603	Belongs to the binding-protein-dependent transport system permease family
Daes_0241	COG1744	ABC transporter substrate-binding protein PnrA-like
Daes_0242	COG0326	Molecular chaperone. Has ATPase activity
Daes_0253	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Daes_0255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Daes_0258	COG1360	Flagellar Motor Protein
Daes_0262	COG1338	Plays a role in the flagellum-specific transport system
Daes_0263	COG1987	bacterial-type flagellum assembly
Daes_0264	COG1067	ATP-dependent peptidase activity
Daes_0266	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Daes_0269	COG0357	Ribosomal RNA small subunit methyltransferase G
Daes_0270	COG2208	phosphoserine phosphatase activity
Daes_0275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Daes_0277	COG0018	arginyl-trna synthetase
Daes_0281	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Daes_0284	COG0166	Belongs to the GPI family
Daes_0291	COG0601	transmembrane transport
Daes_0295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Daes_0296	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Daes_0298	COG1027	Aspartate ammonia-lyase
Daes_0302	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Daes_0302	COG4624	Iron only hydrogenase large subunit, C-terminal domain
Daes_0303	COG2207	Transcriptional regulator
Daes_0304	COG0697	spore germination
Daes_0305	COG0697	spore germination
Daes_0310	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Daes_0312	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Daes_0314	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Daes_0314	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Daes_0316	COG0215	cysteine-tRNA ligase activity
Daes_0334	COG0697	spore germination
Daes_0344	COG3447	MASE1 domain protein
Daes_0344	COG5001	Diguanylate cyclase
Daes_0344	COG5002	protein histidine kinase activity
Daes_0349	COG0778	Nitroreductase
Daes_0352	COG3527	Alpha-acetolactate decarboxylase
Daes_0353	COG0438	transferase activity, transferring glycosyl groups
Daes_0356	COG0840	transmembrane signaling receptor activity
Daes_0359	COG5002	protein histidine kinase activity
Daes_0361	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Daes_0365	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Daes_0366	COG1058	Belongs to the CinA family
Daes_0366	COG1546	Belongs to the CinA family
Daes_0368	COG0437	4 iron, 4 sulfur cluster binding
Daes_0373	COG3447	MASE1 domain protein
Daes_0373	COG5001	Diguanylate cyclase
Daes_0373	COG5002	protein histidine kinase activity
Daes_0376	COG1136	(ABC) transporter
Daes_0376	COG0577	efflux transmembrane transporter activity
Daes_0381	COG1294	oxidase, subunit
Daes_0382	COG1271	oxidase subunit
Daes_0388	COG1408	metallophosphoesterase
Daes_0390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Daes_0397	COG3181	Tripartite tricarboxylate transporter family receptor
Daes_0405	COG2801	Transposase and inactivated derivatives
Daes_0409	COG2184	nucleotidyltransferase activity
Daes_0446	COG4695	Portal protein
Daes_0456	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Daes_0463	COG3093	addiction module antidote protein HigA
Daes_0477	COG2963	transposase activity
Daes_0478	COG2801	Transposase and inactivated derivatives
Daes_0486	COG4974	Belongs to the 'phage' integrase family
Daes_0495	COG2963	transposase activity
Daes_0500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Daes_0501	COG0693	protein deglycase activity
Daes_0502	COG0148	phosphopyruvate hydratase activity
Daes_0503	COG0640	Transcriptional regulator
Daes_0511	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Daes_0513	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Daes_0515	COG4977	sequence-specific DNA binding
Daes_0516	COG5002	protein histidine kinase activity
Daes_0520	COG0778	Nitroreductase
Daes_0521	COG1733	regulation of RNA biosynthetic process
Daes_0522	COG3437	response regulator, receiver
Daes_0522	COG2205	protein histidine kinase activity
Daes_0522	COG3850	Histidine kinase
Daes_0522	COG4999	Histidine kinase
Daes_0523	COG3676	manually curated
Daes_0529	COG1151	hydroxylamine reductase activity
Daes_0531	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Daes_0532	COG0861	Integral membrane protein TerC family
Daes_0533	COG0363	glucosamine-6-phosphate deaminase activity
Daes_0534	COG2207	Transcriptional regulator
Daes_0534	COG3708	Transcriptional regulator
Daes_0538	COG1136	(ABC) transporter
Daes_0542	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Daes_0544	COG0318	PFAM AMP-dependent synthetase and ligase
Daes_0547	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Daes_0548	COG0390	transport system, permease component
Daes_0549	COG2204	response regulator
Daes_0552	COG0438	transferase activity, transferring glycosyl groups
Daes_0554	COG0116	Belongs to the methyltransferase superfamily
Daes_0554	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Daes_0557	COG1366	Belongs to the anti-sigma-factor antagonist family
Daes_0568	COG4771	TonB-dependent receptor
Daes_0574	COG0811	peptide transport
Daes_0575	COG0811	peptide transport
Daes_0576	COG0848	biopolymer transport protein
Daes_0583	COG4771	TonB-dependent receptor
Daes_0585	COG1132	(ABC) transporter
Daes_0586	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Daes_0590	COG1846	Transcriptional regulator
Daes_0592	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Daes_0593	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Daes_0595	COG1027	Aspartate ammonia-lyase
Daes_0599	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Daes_0599	COG4624	Iron only hydrogenase large subunit, C-terminal domain
Daes_0600	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Daes_0601	COG0531	amino acid
Daes_0602	COG0583	DNA-binding transcription factor activity
Daes_0605	COG1136	(ABC) transporter
Daes_0609	COG3706	GGDEF domain
Daes_0609	COG0745	RESPONSE REGULATOR receiver
Daes_0610	COG1490	D-aminoacyl-tRNA deacylase activity
Daes_0612	COG0720	synthase
Daes_0615	COG0471	metal ion transport
Daes_0616	COG2198	Histidine kinase
Daes_0616	COG2205	protein histidine kinase activity
Daes_0616	COG0784	Response regulator, receiver
Daes_0624	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Daes_0625	COG4585	Histidine kinase
Daes_0627	COG2801	Transposase and inactivated derivatives
Daes_0628	COG2963	transposase activity
Daes_0629	COG3210	domain, Protein
Daes_0635	COG1473	amidohydrolase
Daes_0636	COG1760	l-serine dehydratase
Daes_0638	COG3842	ATPase activity
Daes_0639	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Daes_0640	COG0395	ABC-type sugar transport system, permease component
Daes_0642	COG0647	UMP catabolic process
Daes_0644	COG1301	dicarboxylic acid transport
Daes_0646	COG2208	phosphoserine phosphatase activity
Daes_0646	COG2770	Histidine kinase
Daes_0647	COG0840	transmembrane signaling receptor activity
Daes_0654	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Daes_0656	COG0004	ammonium transporteR
Daes_0658	COG3830	Belongs to the UPF0237 family
Daes_0658	COG0560	Phosphoserine phosphatase
Daes_0661	COG0598	Magnesium transport protein CorA
Daes_0663	COG1280	lysine exporter protein (LysE YggA)
Daes_0664	COG0628	permease
Daes_0665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Daes_0666	COG3279	Response regulator of the LytR AlgR family
Daes_0669	COG0427	acetyl-CoA hydrolase
Daes_0674	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Daes_0675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Daes_0684	COG0784	Response regulator, receiver
Daes_0684	COG4191	Histidine kinase
Daes_0687	COG0436	Aminotransferase
Daes_0688	COG0616	signal peptide processing
Daes_0689	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Daes_0690	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
Daes_0691	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Daes_0695	COG2801	Transposase and inactivated derivatives
Daes_0696	COG2963	transposase activity
Daes_0698	COG2226	methyltransferase
Daes_0700	COG0367	asparagine synthase
Daes_0703	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Daes_0705	COG0506	proline dehydrogenase activity
Daes_0706	COG3708	Transcriptional regulator
Daes_0706	COG2207	Transcriptional regulator
Daes_0707	COG1132	(ABC) transporter
Daes_0709	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Daes_0713	COG0438	transferase activity, transferring glycosyl groups
Daes_0715	COG0367	asparagine synthase
Daes_0717	COG0438	transferase activity, transferring glycosyl groups
Daes_0720	COG1546	Belongs to the CinA family
Daes_0723	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Daes_0725	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Daes_0734	COG1797	cobyrinic acid a,c-diamide synthase activity
Daes_0735	COG2270	Major facilitator Superfamily
Daes_0736	COG2078	PFAM AMMECR1 domain protein
Daes_0744	COG0525	valine-tRNA ligase activity
Daes_0747	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Daes_0748	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Daes_0749	COG0702	epimerase
Daes_0751	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Daes_0753	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Daes_0761	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Daes_0762	COG0228	four-way junction DNA binding
Daes_0763	COG1837	Belongs to the UPF0109 family
Daes_0764	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Daes_0765	COG0336	Belongs to the RNA methyltransferase TrmD family
Daes_0765	COG4752	Belongs to the RNA methyltransferase TrmD family
Daes_0766	COG0335	large ribosomal subunit rRNA binding
Daes_0770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Daes_0771	COG1268	BioY protein
Daes_0773	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Daes_0774	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Daes_0775	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Daes_0777	COG2204	response regulator
Daes_0782	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Daes_0784	COG2048	Heterodisulfide reductase, subunit B
Daes_0786	COG0247	lactate metabolic process
Daes_0788	COG5557	Pfam Polysulphide reductase, NrfD
Daes_0789	COG0437	4 iron, 4 sulfur cluster binding
Daes_0789	COG3064	Membrane
Daes_0791	COG0277	FAD linked oxidase domain protein
Daes_0794	COG0653	protein targeting
Daes_0797	COG2226	methyltransferase
Daes_0801	COG0142	geranyltranstransferase activity
Daes_0802	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Daes_0804	COG0840	transmembrane signaling receptor activity
Daes_0806	COG1592	Rubrerythrin
Daes_0807	COG2033	superoxide reductase activity
Daes_0808	COG1773	rubredoxin
Daes_0810	COG1671	Belongs to the UPF0178 family
Daes_0811	COG4895	conserved protein (DUF2196)
Daes_0815	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Daes_0816	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Daes_0817	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Daes_0819	COG0840	transmembrane signaling receptor activity
Daes_0820	COG5002	protein histidine kinase activity
Daes_0821	COG0306	phosphate transporter
Daes_0824	COG0129	dihydroxy-acid dehydratase activity
Daes_0825	COG3547	Transposase (IS116 IS110 IS902 family)
Daes_0827	COG0753	catalase activity
Daes_0829	COG0724	RNA recognition motif
Daes_0831	COG2193	ferroxidase activity
Daes_0833	COG0481	GTPase activity
Daes_0839	COG1595	DNA-templated transcription, initiation
Daes_0842	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Daes_0843	COG0765	amino acid transport
Daes_0845	COG1509	lysine 2,3-aminomutase activity
Daes_0860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Daes_0861	COG0045	succinate-CoA ligase (ADP-forming) activity
Daes_0861	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Daes_0861	COG1042	CoA-binding domain protein
Daes_0862	COG1942	4-Oxalocrotonate Tautomerase
Daes_0863	COG0484	heat shock protein binding
Daes_0864	COG0437	4 iron, 4 sulfur cluster binding
Daes_0864	COG3064	Membrane
Daes_0865	COG5557	Pfam Polysulphide reductase, NrfD
Daes_0867	COG2181	nitrate reductase activity
Daes_0868	COG0247	lactate metabolic process
Daes_0869	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Daes_0870	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Daes_0871	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Daes_0874	COG0196	riboflavin kinase activity
Daes_0875	COG4783	chaperone-mediated protein folding
Daes_0876	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Daes_0878	COG0193	aminoacyl-tRNA hydrolase activity
Daes_0879	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Daes_0880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Daes_0881	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Daes_0883	COG3961	Belongs to the TPP enzyme family
Daes_0884	COG2205	protein histidine kinase activity
Daes_0885	COG0840	transmembrane signaling receptor activity
Daes_0886	COG2353	YceI-like domain
Daes_0888	COG1120	ATPase activity
Daes_0889	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Daes_0894	COG1166	arginine decarboxylase activity
Daes_0895	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Daes_0898	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Daes_0901	COG0534	Mate efflux family protein
Daes_0904	COG2205	protein histidine kinase activity
Daes_0905	COG2172	sigma factor antagonist activity
Daes_0906	COG3180	Ammonia monooxygenase
Daes_0907	COG1570	exodeoxyribonuclease VII activity
Daes_0908	COG0739	heme binding
Daes_0909	COG1722	exodeoxyribonuclease VII activity
Daes_0910	COG0142	geranyltranstransferase activity
Daes_0911	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Daes_0912	COG3012	SEC-C Motif Domain Protein
Daes_0913	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Daes_0917	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Daes_0920	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Daes_0922	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Daes_0924	COG3437	response regulator, receiver
Daes_0924	COG0784	Response regulator, receiver
Daes_0925	COG0784	Response regulator, receiver
Daes_0925	COG4191	Histidine kinase
Daes_0929	COG0513	Belongs to the DEAD box helicase family
Daes_0930	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Daes_0931	COG0724	RNA recognition motif
Daes_0937	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Daes_0945	COG0159	tryptophan synthase activity
Daes_0946	COG0133	tryptophan synthase activity
Daes_0947	COG0135	phosphoribosylanthranilate isomerase activity
Daes_0948	COG0134	indole-3-glycerol-phosphate synthase activity
Daes_0949	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Daes_0950	COG0512	Glutamine amidotransferase of anthranilate synthase
Daes_0950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Daes_0951	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Daes_0953	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Daes_0955	COG1465	3-dehydroquinate synthase
Daes_0956	COG1830	Aldolase
Daes_0957	COG0004	ammonium transporteR
Daes_0958	COG0347	Belongs to the P(II) protein family
Daes_0959	COG2200	EAL domain
Daes_0966	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Daes_0967	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Daes_0968	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Daes_0969	COG5001	Diguanylate cyclase
Daes_0971	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Daes_0971	COG1328	CTP reductase activity
Daes_0974	COG0840	transmembrane signaling receptor activity
Daes_0976	COG0501	Belongs to the peptidase M48B family
Daes_0982	COG0747	negative chemotaxis
Daes_0983	COG0601	transmembrane transport
Daes_0984	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Daes_0985	COG0444	Belongs to the ABC transporter superfamily
Daes_0986	COG1124	(ABC) transporter
Daes_0987	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Daes_0992	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Daes_0999	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Daes_1000	COG5002	protein histidine kinase activity
Daes_1000	COG2205	protein histidine kinase activity
Daes_1000	COG0784	Response regulator, receiver
Daes_1003	COG2204	response regulator
Daes_1006	COG0730	response to heat
Daes_1007	COG2204	response regulator
Daes_1008	COG2204	response regulator
Daes_1009	COG2204	response regulator
Daes_1011	COG2204	response regulator
Daes_1012	COG0574	Belongs to the PEP-utilizing enzyme family
Daes_1012	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Daes_1013	COG0701	Predicted permease
Daes_1016	COG0803	Belongs to the bacterial solute-binding protein 9 family
Daes_1016	COG3443	Belongs to the bacterial solute-binding protein 9 family
Daes_1017	COG1924	4 iron, 4 sulfur cluster binding
Daes_1018	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
Daes_1020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Daes_1021	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Daes_1026	COG0535	radical SAM domain protein
Daes_1026	COG1433	Dinitrogenase iron-molybdenum cofactor
Daes_1030	COG1433	Dinitrogenase iron-molybdenum cofactor
Daes_1030	COG0535	radical SAM domain protein
Daes_1034	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Daes_1035	COG0573	inorganic phosphate transmembrane transporter activity
Daes_1036	COG0573	inorganic phosphate transmembrane transporter activity
Daes_1037	COG0840	transmembrane signaling receptor activity
Daes_1038	COG1032	radical SAM domain protein
Daes_1040	COG0513	Belongs to the DEAD box helicase family
Daes_1043	COG0437	4 iron, 4 sulfur cluster binding
Daes_1045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Daes_1046	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Daes_1047	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
Daes_1048	COG4095	Psort location CytoplasmicMembrane, score
Daes_1049	COG0138	bifunctional purine biosynthesis protein purh
Daes_1050	COG0840	transmembrane signaling receptor activity
Daes_1053	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Daes_1054	COG0470	DNA polymerase III
Daes_1061	COG1027	Aspartate ammonia-lyase
Daes_1065	COG2204	response regulator
Daes_1069	COG1620	l-lactate permease
Daes_1070	COG0277	FAD linked oxidase domain protein
Daes_1071	COG0247	lactate metabolic process
Daes_1072	COG0280	phosphate acetyltransferase
Daes_1072	COG0857	belongs to the CobB CobQ family
Daes_1073	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Daes_1074	COG1556	Lactate utilization protein
Daes_1075	COG1139	Iron-sulfur cluster binding protein
Daes_1076	COG0840	transmembrane signaling receptor activity
Daes_1085	COG1006	Multisubunit Na H antiporter MnhC subunit
Daes_1086	COG0651	ATP synthesis coupled electron transport
Daes_1087	COG0651	ATP synthesis coupled electron transport
Daes_1095	COG4566	intracellular signal transduction
Daes_1100	COG0659	secondary active sulfate transmembrane transporter activity
Daes_1101	COG2204	response regulator
Daes_1103	COG1131	(ABC) transporter
Daes_1105	COG2205	protein histidine kinase activity
Daes_1108	COG0745	RESPONSE REGULATOR receiver
Daes_1109	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Daes_1111	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Daes_1112	COG1749	Flagellar hook protein flgE
Daes_1113	COG1256	bacterial-type flagellum assembly
Daes_1116	COG2205	protein histidine kinase activity
Daes_1117	COG0745	RESPONSE REGULATOR receiver
Daes_1120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Daes_1126	COG1136	(ABC) transporter
Daes_1126	COG0577	efflux transmembrane transporter activity
Daes_1127	COG1136	(ABC) transporter
Daes_1127	COG0577	efflux transmembrane transporter activity
Daes_1134	COG2204	response regulator
Daes_1139	COG1175	transmembrane transport
Daes_1140	COG0395	ABC-type sugar transport system, permease component
Daes_1141	COG3842	ATPase activity
Daes_1142	COG3842	ATPase activity
Daes_1144	COG0243	molybdopterin cofactor binding
Daes_1148	COG1309	transcriptional regulator
Daes_1152	COG1921	L-seryl-tRNASec selenium transferase activity
Daes_1153	COG1362	aminopeptidase activity
Daes_1157	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Daes_1158	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Daes_1159	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Daes_1162	COG2188	Transcriptional regulator
Daes_1163	COG3624	Phosphonate C-P lyase system protein PhnG
Daes_1165	COG3626	phosphonate metabolism
Daes_1166	COG3627	carbon phosphorus lyase activity
Daes_1167	COG4107	phosphonate C-P lyase system protein PhnK
Daes_1168	COG4778	phosphonate C-P lyase system protein PhnL
Daes_1169	COG3454	Phosphonate metabolism
Daes_1170	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Daes_1172	COG3639	organic phosphonate transmembrane transporter activity
Daes_1177	COG0189	ligase activity
Daes_1182	COG1192	Involved in chromosome partitioning
Daes_1184	COG0243	molybdopterin cofactor binding
Daes_1190	COG5002	protein histidine kinase activity
Daes_1191	COG2204	response regulator
Daes_1195	COG1639	'signal transduction protein
Daes_1197	COG0745	RESPONSE REGULATOR receiver
Daes_1198	COG1774	PSP1 C-terminal conserved region
Daes_1199	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Daes_1199	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Daes_1204	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Daes_1205	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Daes_1211	COG0543	2 iron, 2 sulfur cluster binding
Daes_1212	COG0167	dihydroorotate dehydrogenase activity
Daes_1214	COG0385	Bile acid
Daes_1217	COG2067	long-chain fatty acid transport protein
Daes_1218	COG1122	ATPase activity
Daes_1220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Daes_1223	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Daes_1225	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Daes_1226	COG0305	Participates in initiation and elongation during chromosome replication
Daes_1227	COG0359	binds to the 23S rRNA
Daes_1228	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Daes_1229	COG0360	Binds together with S18 to 16S ribosomal RNA
Daes_1230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Daes_1231	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Daes_1233	COG0322	excinuclease ABC activity
Daes_1234	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Daes_1238	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Daes_1241	COG0835	chemotaxis
Daes_1241	COG0784	Response regulator, receiver
Daes_1243	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Daes_1244	COG0640	Transcriptional regulator
Daes_1247	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Daes_1248	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Daes_1249	COG1702	phosphate starvation-inducible protein PhoH
Daes_1250	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Daes_1252	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Daes_1253	COG0137	argininosuccinate synthase activity
Daes_1254	COG0165	Argininosuccinate lyase
Daes_1255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Daes_1256	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Daes_1257	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Daes_1259	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Daes_1260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Daes_1262	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Daes_1267	COG2022	thiamine diphosphate biosynthetic process
Daes_1268	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Daes_1270	COG0352	thiamine-phosphate diphosphorylase activity
Daes_1271	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Daes_1275	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Daes_1278	COG0463	Glycosyl transferase, family 2
Daes_1281	COG0671	phosphoesterase, PA-phosphatase related
Daes_1282	COG0438	transferase activity, transferring glycosyl groups
Daes_1285	COG2045	Belongs to the ComB family
Daes_1286	COG0745	RESPONSE REGULATOR receiver
Daes_1286	COG3706	GGDEF domain
Daes_1288	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Daes_1289	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Daes_1290	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Daes_1291	COG0649	NAD binding
Daes_1292	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Daes_1293	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Daes_1294	COG0839	Belongs to the complex I subunit 6 family
Daes_1295	COG0713	ATP synthesis coupled electron transport
Daes_1296	COG0651	ATP synthesis coupled electron transport
Daes_1300	COG1007	ATP synthesis coupled electron transport
Daes_1304	COG0012	GTP binding
Daes_1305	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Daes_1306	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Daes_1309	COG2827	Endonuclease containing a URI domain
Daes_1311	COG0494	nUDIX hydrolase
Daes_1312	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Daes_1313	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Daes_1314	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Daes_1317	COG1091	dTDP-4-dehydrorhamnose reductase activity
Daes_1319	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Daes_1322	COG4662	Binding-protein-dependent transport system inner membrane component
Daes_1323	COG2998	abc-type tungstate transport system, permease component
Daes_1325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Daes_1327	COG2414	aldehyde ferredoxin oxidoreductase
Daes_1328	COG3676	manually curated
Daes_1331	COG2204	response regulator
Daes_1335	COG4657	Part of a membrane complex involved in electron transport
Daes_1336	COG4660	Part of a membrane complex involved in electron transport
Daes_1338	COG4658	electron transport chain
Daes_1340	COG0484	heat shock protein binding
Daes_1343	COG0492	ferredoxin-NADP+ reductase activity
Daes_1344	COG2205	protein histidine kinase activity
Daes_1344	COG0784	Response regulator, receiver
Daes_1347	COG0745	RESPONSE REGULATOR receiver
Daes_1351	COG2920	part of a sulfur-relay system
Daes_1352	COG0254	rRNA binding
Daes_1353	COG3872	metal-dependent enzyme
Daes_1354	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Daes_1355	COG2890	protein-(glutamine-N5) methyltransferase activity
Daes_1356	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Daes_1362	COG1191	sigma factor activity
Daes_1363	COG0455	bacterial-type flagellum organization
Daes_1365	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Daes_1366	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Daes_1367	COG1684	flagellar biosynthetic protein fliR
Daes_1368	COG0739	heme binding
Daes_1369	COG0037	tRNA processing
Daes_1371	COG1758	RNA polymerase activity
Daes_1372	COG0484	heat shock protein binding
Daes_1373	COG0315	cyclic pyranopterin monophosphate synthase activity
Daes_1374	COG0107	imidazoleglycerol-phosphate synthase activity
Daes_1375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Daes_1376	COG0484	heat shock protein binding
Daes_1379	COG0006	proline dipeptidase activity
Daes_1381	COG1454	alcohol dehydrogenase
Daes_1388	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Daes_1388	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Daes_1391	COG0842	Transport permease protein
Daes_1392	COG1131	(ABC) transporter
Daes_1396	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Daes_1397	COG4591	ABC-type transport system involved in lipoprotein release permease component
Daes_1398	COG1136	(ABC) transporter
Daes_1399	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Daes_1401	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Daes_1402	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Daes_1403	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Daes_1404	COG3494	Protein of unknown function (DUF1009)
Daes_1407	COG1295	ribonuclease BN
Daes_1409	COG0343	queuine tRNA-ribosyltransferase activity
Daes_1410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Daes_1411	COG1324	tolerance protein
Daes_1414	COG0529	Catalyzes the synthesis of activated sulfate
Daes_1414	COG2046	Belongs to the sulfate adenylyltransferase family
Daes_1415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Daes_1419	COG0848	biopolymer transport protein
Daes_1421	COG0823	Involved in the tonB-independent uptake of proteins
Daes_1423	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Daes_1425	COG0424	maF-like protein
Daes_1427	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Daes_1428	COG0837	glucose binding
Daes_1429	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Daes_1433	COG1129	ABC transporter
Daes_1434	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Daes_1438	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Daes_1440	COG0436	Aminotransferase
Daes_1442	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Daes_1443	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Daes_1444	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Daes_1445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Daes_1448	COG1013	pyruvate-flavodoxin oxidoreductase activity
Daes_1449	COG0488	(ABC) transporter
Daes_1451	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Daes_1452	COG0439	Biotin carboxylase
Daes_1453	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Daes_1457	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Daes_1461	COG0840	transmembrane signaling receptor activity
Daes_1463	COG3676	manually curated
Daes_1464	COG2801	Transposase and inactivated derivatives
Daes_1465	COG2963	transposase activity
Daes_1466	COG3676	manually curated
Daes_1467	COG0590	tRNA wobble adenosine to inosine editing
Daes_1468	COG0047	phosphoribosylformylglycinamidine synthase activity
Daes_1469	COG0504	CTP synthase activity
Daes_1470	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Daes_1471	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Daes_1474	COG1137	ATPase activity
Daes_1475	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Daes_1477	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Daes_1478	COG1660	Displays ATPase and GTPase activities
Daes_1480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Daes_1482	COG1227	inorganic diphosphatase activity
Daes_1483	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Daes_1485	COG0776	regulation of translation
Daes_1486	COG0455	bacterial-type flagellum organization
Daes_1487	COG3706	GGDEF domain
Daes_1487	COG0745	RESPONSE REGULATOR receiver
Daes_1488	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Daes_1489	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Daes_1490	COG4535	Mg2 and Co2 transporter CorC
Daes_1491	COG0445	tRNA wobble uridine modification
Daes_1492	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Daes_1494	COG0402	S-adenosylhomocysteine deaminase activity
Daes_1495	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Daes_1496	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Daes_1497	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Daes_1498	COG0776	regulation of translation
Daes_1500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Daes_1501	COG1610	YqeY-like protein
Daes_1502	COG1193	negative regulation of DNA recombination
Daes_1503	COG0358	DNA primase activity
Daes_1505	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Daes_1507	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Daes_1508	COG0105	UTP biosynthetic process
Daes_1509	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Daes_1510	COG4120	Belongs to the binding-protein-dependent transport system permease family
Daes_1514	COG0793	Belongs to the peptidase S41A family
Daes_1517	COG2264	protein methyltransferase activity
Daes_1519	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Daes_1524	COG0069	glutamate synthase activity
Daes_1525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Daes_1526	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Daes_1527	COG0067	glutamate synthase
Daes_1529	COG1862	Preprotein translocase
Daes_1530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Daes_1531	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Daes_1532	COG0563	adenylate kinase activity
Daes_1533	COG0037	tRNA processing
Daes_1535	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Daes_1536	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Daes_1537	COG1648	precorrin-2 dehydrogenase activity
Daes_1537	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Daes_1539	COG4641	Protein conserved in bacteria
Daes_1542	COG0019	diaminopimelate decarboxylase activity
Daes_1544	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Daes_1545	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Daes_1549	COG0617	tRNA 3'-terminal CCA addition
Daes_1550	COG4974	Belongs to the 'phage' integrase family
Daes_1551	COG0436	Aminotransferase
Daes_1556	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Daes_1557	COG0149	triose-phosphate isomerase activity
Daes_1558	COG0126	phosphoglycerate kinase activity
Daes_1559	COG0456	acetyltransferase
Daes_1561	COG0483	inositol monophosphate 1-phosphatase activity
Daes_1564	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Daes_1567	COG1187	pseudouridine synthase activity
Daes_1569	COG1674	ftsk spoiiie
Daes_1570	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Daes_1571	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Daes_1572	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Daes_1576	COG1968	undecaprenyl-diphosphatase activity
Daes_1579	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Daes_1582	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Daes_1592	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Daes_1593	COG0358	DNA primase activity
Daes_1607	COG0017	Asparaginyl-tRNA synthetase
Daes_1652	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Daes_1657	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Daes_1660	COG0668	transmembrane transport
Daes_1661	COG0501	Belongs to the peptidase M48B family
Daes_1668	COG3676	manually curated
Daes_1671	COG2198	Histidine kinase
Daes_1671	COG5002	protein histidine kinase activity
Daes_1671	COG0784	Response regulator, receiver
Daes_1674	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Daes_1678	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Daes_1680	COG0439	Biotin carboxylase
Daes_1682	COG0617	tRNA 3'-terminal CCA addition
Daes_1684	COG5002	protein histidine kinase activity
Daes_1684	COG2205	protein histidine kinase activity
Daes_1684	COG0784	Response regulator, receiver
Daes_1690	COG0719	Fe-S assembly protein
Daes_1691	COG0396	ATPase activity
Daes_1693	COG0835	chemotaxis
Daes_1695	COG0440	acetolactate synthase activity
Daes_1696	COG0028	Belongs to the TPP enzyme family
Daes_1697	COG2249	NAD(P)H dehydrogenase (quinone) activity
Daes_1699	COG1067	ATP-dependent peptidase activity
Daes_1707	COG1045	serine acetyltransferase
Daes_1709	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Daes_1710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Daes_1716	COG2239	Acts as a magnesium transporter
Daes_1719	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Daes_1721	COG0569	domain protein
Daes_1722	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Daes_1723	COG0072	phenylalanine-tRNA ligase activity
Daes_1723	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Daes_1726	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Daes_1727	COG0268	Binds directly to 16S ribosomal RNA
Daes_1728	COG0751	glycine-tRNA ligase activity
Daes_1729	COG0752	glycyl-tRNA synthetase alpha subunit
Daes_1730	COG1381	Involved in DNA repair and RecF pathway recombination
Daes_1732	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Daes_1735	COG0835	chemotaxis
Daes_1738	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Daes_1739	COG0736	holo-[acyl-carrier-protein] synthase activity
Daes_1740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Daes_1740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Daes_1741	COG0516	GMP reductase activity
Daes_1741	COG0517	IMP dehydrogenase activity
Daes_1744	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Daes_1745	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Daes_1747	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Daes_1748	COG3481	metal-dependent phosphohydrolase, HD sub domain
Daes_1749	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Daes_1752	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Daes_1753	COG0765	amino acid transport
Daes_1756	COG0750	zinc metalloprotease
Daes_1758	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Daes_1759	COG0444	Belongs to the ABC transporter superfamily
Daes_1760	COG4608	Belongs to the ABC transporter superfamily
Daes_1763	COG1122	ATPase activity
Daes_1764	COG0534	Mate efflux family protein
Daes_1769	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Daes_1771	COG2267	carboxylic ester hydrolase activity
Daes_1772	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Daes_1773	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Daes_1774	COG0440	acetolactate synthase activity
Daes_1775	COG0028	Belongs to the TPP enzyme family
Daes_1777	COG1872	DUF167
Daes_1783	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Daes_1787	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Daes_1788	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Daes_1789	COG0742	ribosomal rna small subunit methyltransferase
Daes_1790	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Daes_1792	COG0697	spore germination
Daes_1795	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Daes_1798	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Daes_1803	COG0534	Mate efflux family protein
Daes_1804	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Daes_1805	COG3676	manually curated
Daes_1806	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Daes_1807	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Daes_1808	COG0556	nucleotide-excision repair
Daes_1810	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Daes_1811	COG0542	response to heat
Daes_1812	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Daes_1814	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Daes_1815	COG1993	acr, cog1993
Daes_1816	COG2201	protein-glutamate methylesterase activity
Daes_1817	COG0643	Histidine kinase
Daes_1817	COG2198	Histidine kinase
Daes_1818	COG0840	transmembrane signaling receptor activity
Daes_1820	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Daes_1822	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Daes_1823	COG0492	ferredoxin-NADP+ reductase activity
Daes_1824	COG3118	belongs to the thioredoxin family
Daes_1825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Daes_1826	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Daes_1831	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Daes_1832	COG0489	protein tyrosine kinase activity
Daes_1834	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Daes_1838	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Daes_1840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Daes_1841	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Daes_1842	COG0740	serine-type endopeptidase activity
Daes_1843	COG0544	peptidyl-prolyl cis-trans isomerase activity
Daes_1844	COG0351	phosphomethylpyrimidine kinase
Daes_1848	COG4957	zinc ion binding
Daes_1850	COG0017	Asparaginyl-tRNA synthetase
Daes_1851	COG0552	protein localization to endoplasmic reticulum
Daes_1852	COG0539	negative regulation of cytoplasmic translation
Daes_1853	COG0564	pseudouridine synthase activity
Daes_1855	COG1074	ATP-dependent DNA helicase activity
Daes_1858	COG0579	oxidoreductase
Daes_1859	COG2070	2-Nitropropane dioxygenase
Daes_1860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Daes_1861	COG4974	Belongs to the 'phage' integrase family
Daes_1863	COG1418	mRNA catabolic process
Daes_1863	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Daes_1865	COG0758	DNA mediated transformation
Daes_1871	COG0643	Histidine kinase
Daes_1871	COG2198	Histidine kinase
Daes_1873	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Daes_1875	COG2201	protein-glutamate methylesterase activity
Daes_1881	COG2801	Transposase and inactivated derivatives
Daes_1882	COG2963	transposase activity
Daes_1883	COG1696	Membrane protein involved in D-alanine export
Daes_1886	COG1215	transferase activity, transferring glycosyl groups
Daes_1889	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Daes_1889	COG1918	ferrous iron import across plasma membrane
Daes_1890	COG1918	ferrous iron import across plasma membrane
Daes_1894	COG0735	belongs to the Fur family
Daes_1896	COG3864	Putative metallopeptidase domain
Daes_1901	COG0745	RESPONSE REGULATOR receiver
Daes_1901	COG3706	GGDEF domain
Daes_1903	COG1760	l-serine dehydratase
Daes_1905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Daes_1906	COG0765	amino acid transport
Daes_1909	COG0473	3-isopropylmalate dehydrogenase activity
Daes_1910	COG0066	3-isopropylmalate dehydratase activity
Daes_1911	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Daes_1912	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Daes_1913	COG1183	phosphatidylcholine synthase activity
Daes_1914	COG0688	phosphatidylethanolamine metabolic process
Daes_1917	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Daes_1921	COG0588	phosphoglycerate mutase activity
Daes_1923	COG1216	Glycosyl transferase, family 2
Daes_1923	COG0463	Glycosyl transferase, family 2
Daes_1928	COG0521	Mo-molybdopterin cofactor biosynthetic process
Daes_1940	COG2801	Transposase and inactivated derivatives
Daes_1941	COG2963	transposase activity
Daes_1944	COG1342	Belongs to the UPF0251 family
Daes_1953	COG0493	'glutamate synthase
Daes_1954	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Daes_1954	COG0069	glutamate synthase activity
Daes_1957	COG1959	2 iron, 2 sulfur cluster binding
Daes_1960	COG0628	permease
Daes_1962	COG0765	amino acid transport
Daes_1971	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Daes_1972	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Daes_1973	COG3959	Transketolase, thiamine diphosphate binding domain
Daes_1974	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Daes_1975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Daes_1977	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Daes_1977	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Daes_1980	COG1215	transferase activity, transferring glycosyl groups
Daes_1984	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Daes_1985	COG2089	acid synthase
Daes_1987	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Daes_1988	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Daes_1990	COG1028	Short-chain dehydrogenase reductase Sdr
Daes_1991	COG0107	imidazoleglycerol-phosphate synthase activity
Daes_1992	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Daes_1996	COG4251	negative regulation of phosphorylation
Daes_1997	COG0784	Response regulator, receiver
Daes_1998	COG4251	negative regulation of phosphorylation
Daes_2005	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Daes_2005	COG1918	ferrous iron import across plasma membrane
Daes_2007	COG0138	bifunctional purine biosynthesis protein purh
Daes_2009	COG1815	bacterial-type flagellum-dependent cell motility
Daes_2011	COG1677	Flagellar hook-basal body complex protein FliE
Daes_2013	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Daes_2015	COG1157	protein secretion by the type III secretion system
Daes_2016	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Daes_2018	COG0789	Transcriptional regulator
Daes_2019	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Daes_2019	COG0072	phenylalanine-tRNA ligase activity
Daes_2020	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Daes_2021	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Daes_2022	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Daes_2023	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Daes_2024	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Daes_2030	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
Daes_2033	COG1335	isochorismatase
Daes_2034	COG1032	radical SAM domain protein
Daes_2035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Daes_2035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Daes_2038	COG1830	Aldolase
Daes_2044	COG0859	PFAM glycosyl transferase family 9
Daes_2052	COG0601	transmembrane transport
Daes_2053	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Daes_2054	COG0444	Belongs to the ABC transporter superfamily
Daes_2055	COG4608	Belongs to the ABC transporter superfamily
Daes_2057	COG2963	transposase activity
Daes_2058	COG2801	Transposase and inactivated derivatives
Daes_2059	COG0745	RESPONSE REGULATOR receiver
Daes_2060	COG0446	pyridine nucleotide-disulphide oxidoreductase
Daes_2061	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Daes_2064	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Daes_2065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Daes_2066	COG1053	succinate dehydrogenase
Daes_2068	COG0612	Peptidase, M16
Daes_2070	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Daes_2071	COG0569	domain protein
Daes_2074	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Daes_2080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Daes_2081	COG0439	Biotin carboxylase
Daes_2084	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Daes_2088	COG1013	pyruvate-flavodoxin oxidoreductase activity
Daes_2089	COG0674	pyruvate-flavodoxin oxidoreductase activity
Daes_2089	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Daes_2092	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Daes_2093	COG0765	amino acid transport
Daes_2094	COG0765	amino acid transport
Daes_2095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Daes_2101	COG0402	S-adenosylhomocysteine deaminase activity
Daes_2102	COG5557	Pfam Polysulphide reductase, NrfD
Daes_2103	COG0437	4 iron, 4 sulfur cluster binding
Daes_2104	COG0243	molybdopterin cofactor binding
Daes_2107	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Daes_2109	COG3956	TIGRFAM MazG family protein
Daes_2111	COG3608	succinylglutamate desuccinylase aspartoacylase
Daes_2111	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Daes_2112	COG2068	MobA-Related Protein
Daes_2117	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Daes_2118	COG0513	Belongs to the DEAD box helicase family
Daes_2120	COG0730	response to heat
Daes_2121	COG1160	GTP binding
Daes_2122	COG0840	transmembrane signaling receptor activity
Daes_2123	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Daes_2124	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Daes_2128	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Daes_2131	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Daes_2132	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Daes_2134	COG4786	Flagellar basal body rod
Daes_2134	COG1256	bacterial-type flagellum assembly
Daes_2134	COG4786	Flagellar basal body rod
Daes_2134	COG1256	bacterial-type flagellum assembly
Daes_2137	COG1706	bacterial-type flagellum-dependent cell motility
Daes_2138	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Daes_2141	COG4786	Flagellar basal body rod
Daes_2142	COG0779	Required for maturation of 30S ribosomal subunits
Daes_2143	COG0195	Participates in both transcription termination and antitermination
Daes_2145	COG3266	domain, Protein
Daes_2145	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Daes_2145	COG3266	domain, Protein
Daes_2145	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Daes_2147	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Daes_2149	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Daes_2150	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Daes_2151	COG1185	polyribonucleotide nucleotidyltransferase activity
Daes_2152	COG1355	regulation of microtubule-based process
Daes_2154	COG2204	response regulator
Daes_2156	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Daes_2159	COG1469	GTP cyclohydrolase I activity
Daes_2160	COG0864	Transcriptional regulator
Daes_2162	COG0509	glycine decarboxylation via glycine cleavage system
Daes_2163	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Daes_2164	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Daes_2165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Daes_2166	COG1028	Short-chain dehydrogenase reductase Sdr
Daes_2175	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Daes_2180	COG0052	Belongs to the universal ribosomal protein uS2 family
Daes_2181	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Daes_2182	COG0528	UMP kinase activity
Daes_2183	COG0233	cytoplasmic translational termination
Daes_2184	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Daes_2185	COG4589	Belongs to the CDS family
Daes_2186	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Daes_2187	COG0750	zinc metalloprotease
Daes_2188	COG1214	PFAM Peptidase M22, glycoprotease
Daes_2189	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Daes_2190	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Daes_2196	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Daes_2197	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Daes_2199	COG0438	transferase activity, transferring glycosyl groups
Daes_2203	COG2885	chlorophyll binding
Daes_2203	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Daes_2204	COG0535	radical SAM domain protein
Daes_2205	COG0113	porphobilinogen synthase activity
Daes_2206	COG0535	radical SAM domain protein
Daes_2209	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Daes_2212	COG1012	belongs to the aldehyde dehydrogenase family
Daes_2213	COG1522	sequence-specific DNA binding
Daes_2214	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Daes_2215	COG1127	ABC transporter
Daes_2218	COG3028	Belongs to the UPF0307 family
Daes_2220	COG0697	spore germination
Daes_2221	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Daes_2223	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Daes_2224	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Daes_2226	COG0583	DNA-binding transcription factor activity
Daes_2227	COG0203	ribosomal protein L17
Daes_2228	COG0202	RNA polymerase activity
Daes_2229	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Daes_2230	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Daes_2231	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Daes_2232	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Daes_2235	COG0200	Binds to the 23S rRNA
Daes_2236	COG1841	ribosomal large subunit assembly
Daes_2237	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Daes_2238	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Daes_2239	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Daes_2240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Daes_2241	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Daes_2242	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Daes_2243	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Daes_2244	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Daes_2245	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Daes_2246	COG0255	Belongs to the universal ribosomal protein uL29 family
Daes_2247	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Daes_2248	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Daes_2249	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Daes_2250	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Daes_2251	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Daes_2252	COG0089	rRNA binding
Daes_2253	COG0088	Forms part of the polypeptide exit tunnel
Daes_2254	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Daes_2255	COG0051	transcription antitermination factor activity, RNA binding
Daes_2256	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Daes_2257	COG0049	tRNA binding
Daes_2258	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Daes_2259	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Daes_2260	COG0085	RNA polymerase activity
Daes_2261	COG0222	ribosome binding
Daes_2262	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Daes_2263	COG0081	regulation of translation
Daes_2264	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Daes_2265	COG0250	Participates in transcription elongation, termination and antitermination
Daes_2266	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Daes_2267	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Daes_2268	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Daes_2269	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Daes_2269	COG3116	cell division
Daes_2270	COG0835	chemotaxis
Daes_2270	COG0784	Response regulator, receiver
Daes_2272	COG0409	Hydrogenase expression formation protein
Daes_2276	COG1181	Belongs to the D-alanine--D-alanine ligase family
Daes_2279	COG0505	Belongs to the CarA family
Daes_2282	COG1053	succinate dehydrogenase
Daes_2284	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Daes_2285	COG0494	nUDIX hydrolase
Daes_2286	COG0009	L-threonylcarbamoyladenylate synthase
Daes_2287	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Daes_2288	COG2204	response regulator
Daes_2290	COG0643	Histidine kinase
Daes_2290	COG2198	Histidine kinase
Daes_2291	COG4822	anaerobic cobalamin biosynthetic process
Daes_2292	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Daes_2293	COG1120	ATPase activity
Daes_2296	COG4822	anaerobic cobalamin biosynthetic process
Daes_2302	COG0321	lipoyl(octanoyl) transferase activity
Daes_2303	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Daes_2304	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Daes_2309	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Daes_2312	COG0284	orotidine-5'-phosphate decarboxylase activity
Daes_2313	COG0194	GDP metabolic process
Daes_2314	COG2052	Domain of unknown function (DUF370)
Daes_2315	COG1561	YicC-like family, N-terminal region
Daes_2317	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Daes_2320	COG0482	sulfurtransferase activity
Daes_2321	COG0371	Dehydrogenase
Daes_2323	COG0154	amidase activity
Daes_2324	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Daes_2326	COG0443	Heat shock 70 kDa protein
Daes_2327	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Daes_2330	COG0429	hydrolase of the alpha beta-hydrolase fold
Daes_2332	COG0542	response to heat
Daes_2335	COG2823	Periplasmic or secreted lipoprotein
Daes_2336	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Daes_2338	COG0564	pseudouridine synthase activity
Daes_2339	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Daes_2340	COG2233	PERMEase
Daes_2341	COG0463	Glycosyl transferase, family 2
Daes_2342	COG0668	transmembrane transport
Daes_2343	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Daes_2350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Daes_2351	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Daes_2358	COG1216	Glycosyl transferase, family 2
Daes_2361	COG1278	Cold shock
Daes_2362	COG1119	ATPase activity
Daes_2363	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
Daes_2364	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Daes_2365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Daes_2367	COG0442	prolyl-tRNA aminoacylation
Daes_2368	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Daes_2369	COG0840	transmembrane signaling receptor activity
Daes_2373	COG3260	NADH ubiquinone oxidoreductase 20
Daes_2376	COG0175	sulfate reduction
Daes_2379	COG2801	Transposase and inactivated derivatives
Daes_2386	COG3778	Protein conserved in bacteria
Daes_2387	COG3299	homolog of phage Mu protein gp47
Daes_2388	COG4381	Mu-like prophage protein gp46
Daes_2389	COG4384	Bacteriophage Mu Gp45 protein
Daes_2391	COG4228	DNA circulation
Daes_2394	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
Daes_2396	COG4386	tail sheath protein
Daes_2402	COG4397	Mu-like prophage major head subunit gpT
Daes_2406	COG4383	Mu-like prophage protein gp29
Daes_2407	COG4373	Mu-like prophage FluMu protein gp28
Daes_2425	COG3267	Type II secretory pathway component ExeA
Daes_2425	COG3409	Peptidoglycan-binding domain 1 protein
Daes_2437	COG0277	FAD linked oxidase domain protein
Daes_2438	COG3852	Histidine kinase
Daes_2440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Daes_2441	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Daes_2442	COG0681	Belongs to the peptidase S26 family
Daes_2443	COG1216	Glycosyl transferase, family 2
Daes_2444	COG0037	tRNA processing
Daes_2446	COG2204	response regulator
Daes_2447	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Daes_2449	COG2801	Transposase and inactivated derivatives
Daes_2450	COG2963	transposase activity
Daes_2451	COG3676	manually curated
Daes_2453	COG0131	Imidazoleglycerol-phosphate dehydratase
Daes_2454	COG0805	protein transport
Daes_2455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Daes_2456	COG0519	Catalyzes the synthesis of GMP from XMP
Daes_2457	COG0517	IMP dehydrogenase activity
Daes_2457	COG0516	GMP reductase activity
Daes_2459	COG0411	ABC transporter
Daes_2461	COG0559	Belongs to the binding-protein-dependent transport system permease family
Daes_2465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Daes_2467	COG1131	(ABC) transporter
Daes_2468	COG1138	Cytochrome C-type biogenesis protein
Daes_2469	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Daes_2470	COG1253	flavin adenine dinucleotide binding
Daes_2472	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Daes_2473	COG1994	Peptidase M50
Daes_2474	COG0180	Tryptophanyl-tRNA synthetase
Daes_2475	COG1047	Peptidyl-prolyl cis-trans
Daes_2477	COG2853	Lipoprotein
Daes_2479	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Daes_2479	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Daes_2482	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Daes_2483	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Daes_2492	COG0730	response to heat
Daes_2493	COG1304	FMN binding
Daes_2494	COG2186	Transcriptional regulator
Daes_2496	COG1408	metallophosphoesterase
Daes_2498	COG1328	CTP reductase activity
Daes_2498	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Daes_2507	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Daes_2508	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Daes_2514	COG1254	Belongs to the acylphosphatase family
Daes_2515	COG5002	protein histidine kinase activity
Daes_2517	COG0835	chemotaxis
Daes_2517	COG0784	Response regulator, receiver
Daes_2520	COG0745	RESPONSE REGULATOR receiver
Daes_2521	COG5002	protein histidine kinase activity
Daes_2523	COG2202	Pas domain
Daes_2523	COG2205	protein histidine kinase activity
Daes_2524	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Daes_2529	COG2963	transposase activity
Daes_2530	COG2801	Transposase and inactivated derivatives
Daes_2545	COG0572	uridine kinase
Daes_2546	COG1494	fructose-1,6-bisphosphatase
Daes_2548	COG2204	response regulator
Daes_2550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Daes_2551	COG0191	fructose-bisphosphate aldolase activity
Daes_2552	COG0469	pyruvate kinase activity
Daes_2553	COG0126	phosphoglycerate kinase activity
Daes_2554	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Daes_2556	COG0644	oxidoreductase
Daes_2557	COG2801	Transposase and inactivated derivatives
Daes_2558	COG2963	transposase activity
Daes_2560	COG2801	Transposase and inactivated derivatives
Daes_2563	COG3210	domain, Protein
Daes_2565	COG3676	manually curated
Daes_2572	COG1847	R3H domain protein
Daes_2573	COG0706	membrane insertase activity
Daes_2574	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Daes_2575	COG0594	ribonuclease P activity
Daes_2576	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Daes_2579	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Daes_2583	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Daes_2584	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Daes_2586	COG0737	Belongs to the 5'-nucleotidase family
Daes_2588	COG3123	guanosine phosphorylase activity
Daes_2597	COG1945	arginine decarboxylase activity
Daes_2601	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Daes_2602	COG0459	protein refolding
Daes_2603	COG2329	Antibiotic biosynthesis monooxygenase
Daes_2605	COG2414	aldehyde ferredoxin oxidoreductase
Daes_2608	COG0798	PFAM Bile acid sodium symporter
Daes_2612	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Daes_2613	COG0217	transcriptional regulatory protein
Daes_2614	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Daes_2616	COG0632	four-way junction helicase activity
Daes_2617	COG2255	four-way junction helicase activity
Daes_2618	COG1773	rubredoxin
Daes_2621	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Daes_2625	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Daes_2629	COG3447	MASE1 domain protein
Daes_2629	COG3447	MASE1 domain protein
Daes_2629	COG5001	Diguanylate cyclase
Daes_2629	COG5002	protein histidine kinase activity
Daes_2629	COG5002	protein histidine kinase activity
Daes_2629	COG5001	Diguanylate cyclase
Daes_2635	COG2204	response regulator
Daes_2636	COG2204	response regulator
Daes_2637	COG2204	response regulator
Daes_2638	COG2204	response regulator
Daes_2642	COG0247	lactate metabolic process
Daes_2653	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Daes_2654	COG0318	PFAM AMP-dependent synthetase and ligase
Daes_2657	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Daes_2658	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Daes_2659	COG2962	Rard protein
Daes_2670	COG3072	Adenylate cyclase
Daes_2671	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Daes_2672	COG1121	(ABC) transporter
Daes_2674	COG1472	Belongs to the glycosyl hydrolase 3 family
Daes_2676	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
Daes_2677	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Daes_2678	COG0538	isocitrate dehydrogenase activity
Daes_2683	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Daes_2685	COG1129	ABC transporter
Daes_2688	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Daes_2690	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
Daes_2692	COG4191	Histidine kinase
Daes_2693	COG1971	Probably functions as a manganese efflux pump
Daes_2694	COG2204	response regulator
Daes_2695	COG2204	response regulator
Daes_2698	COG2204	response regulator
Daes_2705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Daes_2707	COG0438	transferase activity, transferring glycosyl groups
Daes_2713	COG1509	lysine 2,3-aminomutase activity
Daes_2714	COG1181	Belongs to the D-alanine--D-alanine ligase family
Daes_2715	COG1181	Belongs to the D-alanine--D-alanine ligase family
Daes_2718	COG0406	alpha-ribazole phosphatase activity
Daes_2723	COG3706	GGDEF domain
Daes_2723	COG5001	Diguanylate cyclase
Daes_2723	COG2203	Gaf domain
Daes_2723	COG4251	negative regulation of phosphorylation
Daes_2726	COG0557	exoribonuclease II activity
Daes_2727	COG1663	tetraacyldisaccharide 4'-kinase activity
Daes_2728	COG0670	Belongs to the BI1 family
Daes_2729	COG3920	Histidine kinase
Daes_2734	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Daes_2735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Daes_2736	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Daes_2737	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Daes_2740	COG0310	cobalt ion transport
Daes_2742	COG1959	2 iron, 2 sulfur cluster binding
Daes_2745	COG0724	RNA recognition motif
Daes_2748	COG0489	protein tyrosine kinase activity
Daes_2750	COG2204	response regulator
Daes_2751	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Daes_2752	COG0375	protein maturation
Daes_2754	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Daes_2756	COG0456	acetyltransferase
Daes_2757	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Daes_2758	COG0601	transmembrane transport
Daes_2763	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Daes_2764	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Daes_2769	COG3437	response regulator, receiver
Daes_2770	COG0469	pyruvate kinase activity
Daes_2771	COG2001	Belongs to the MraZ family
Daes_2772	COG0275	rRNA processing
Daes_2775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Daes_2776	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Daes_2777	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Daes_2778	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Daes_2779	COG0772	Belongs to the SEDS family
Daes_2780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Daes_2781	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Daes_2782	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Daes_2786	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Daes_2787	COG3547	Transposase (IS116 IS110 IS902 family)
Daes_2788	COG2801	Transposase and inactivated derivatives
Daes_2792	COG3547	Transposase (IS116 IS110 IS902 family)
Daes_2793	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Daes_2794	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Daes_2795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Daes_2797	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Daes_2798	COG0416	fatty acid biosynthetic process
Daes_2799	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Daes_2801	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Daes_2805	COG0437	4 iron, 4 sulfur cluster binding
Daes_2806	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Daes_2807	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Daes_2808	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Daes_2810	COG4191	Histidine kinase
Daes_2813	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Daes_2813	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Daes_2814	COG2264	protein methyltransferase activity
Daes_2818	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Daes_2818	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Daes_2819	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Daes_2820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Daes_2822	COG0725	ABC transporter, periplasmic molybdate-binding protein
Daes_2827	COG2003	Belongs to the UPF0758 family
Daes_2828	COG1254	Belongs to the acylphosphatase family
Daes_2829	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Daes_2835	COG0181	hydroxymethylbilane synthase activity
Daes_2842	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Daes_2843	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Daes_2851	COG0559	Belongs to the binding-protein-dependent transport system permease family
Daes_2852	COG1022	Amp-dependent synthetase and ligase
Daes_2856	COG0590	tRNA wobble adenosine to inosine editing
Daes_2859	COG0497	DNA recombination
Daes_2860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Daes_2871	COG0778	Nitroreductase
Daes_2874	COG1040	competence protein
Daes_2875	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Daes_2876	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Daes_2877	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Daes_2878	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Daes_2879	COG2814	Major facilitator Superfamily
Daes_2882	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Daes_2883	COG2703	oxygen carrier activity
Daes_2884	COG0303	'Molybdopterin
Daes_2886	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Daes_2894	COG5002	protein histidine kinase activity
Daes_2899	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Daes_2900	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Daes_2903	COG0686	Belongs to the AlaDH PNT family
Daes_2913	COG4964	Belongs to the GSP D family
Daes_2917	COG2204	response regulator
Daes_2922	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Daes_2924	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Daes_2930	COG3676	manually curated
Daes_2935	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Daes_2935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Daes_2937	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Daes_2945	COG0791	NLP P60 protein
Daes_2946	COG0459	protein refolding
Daes_2947	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Daes_2948	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Daes_2955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Daes_2956	COG2770	Histidine kinase
Daes_2956	COG2208	phosphoserine phosphatase activity
Daes_2961	COG0012	GTP binding
Daes_2966	COG0840	transmembrane signaling receptor activity
Daes_2969	COG0784	Response regulator, receiver
Daes_2969	COG0835	chemotaxis
Daes_2970	COG2089	acid synthase
Daes_2972	COG0318	PFAM AMP-dependent synthetase and ligase
Daes_2982	COG1797	cobyrinic acid a,c-diamide synthase activity
Daes_2984	COG2221	Nitrite and sulphite reductase 4Fe-4S
Daes_2985	COG2221	Nitrite and sulphite reductase 4Fe-4S
Daes_2988	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Daes_2989	COG4191	Histidine kinase
Daes_2991	COG3547	Transposase (IS116 IS110 IS902 family)
Daes_2992	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Daes_2995	COG0280	phosphate acetyltransferase
Daes_2995	COG0281	malic enzyme
Daes_3000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Daes_3005	COG0101	tRNA pseudouridine synthase activity
Daes_3006	COG0697	spore germination
Daes_3009	COG0432	Pfam Uncharacterised protein family UPF0047
Daes_3013	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Daes_3014	COG0708	Exodeoxyribonuclease III
Daes_3016	COG2081	HI0933 family
Daes_3017	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Daes_3018	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Daes_3019	COG0589	response to stress
Daes_3025	COG0411	ABC transporter
Daes_3026	COG2113	Glycine betaine
Daes_3027	COG4176	ABC-type proline glycine betaine transport system permease component
Daes_3028	COG4175	Glycine betaine
Daes_3035	COG2046	Belongs to the sulfate adenylyltransferase family
Daes_3038	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Daes_3043	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Daes_3044	COG1749	Flagellar hook protein flgE
Daes_3046	COG0571	ribonuclease III activity
Daes_3048	COG0857	belongs to the CobB CobQ family
Daes_3051	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Daes_3051	COG0519	Catalyzes the synthesis of GMP from XMP
Daes_3052	COG0616	signal peptide processing
Daes_3053	COG0539	negative regulation of cytoplasmic translation
Daes_3054	COG0704	Plays a role in the regulation of phosphate uptake
Daes_3055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Daes_3060	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Daes_3062	COG1683	Conserved Protein
Daes_3071	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Daes_3073	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Daes_3074	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Daes_3077	COG0709	Synthesizes selenophosphate from selenide and ATP
Daes_3078	COG0784	Response regulator, receiver
Daes_3078	COG2205	protein histidine kinase activity
Daes_3080	COG1607	acyl-coa hydrolase
Daes_3081	COG0346	lactoylglutathione lyase activity
Daes_3083	COG1489	DNA binding
Daes_3088	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Daes_3091	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Daes_3092	COG3238	Protein conserved in bacteria
Daes_3093	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Daes_3095	COG3547	Transposase (IS116 IS110 IS902 family)
Daes_3099	COG2226	methyltransferase
Daes_3101	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Daes_3102	COG1692	metallophosphoesterase
Daes_3104	COG1418	mRNA catabolic process
Daes_3107	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Daes_3108	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Daes_3109	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Daes_3110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Daes_3111	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Daes_3112	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Daes_3113	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Daes_3116	COG0772	Belongs to the SEDS family
Daes_3117	COG0768	penicillin binding
Daes_3120	COG1077	Cell shape determining protein MreB Mrl
Daes_3123	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Daes_3124	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Daes_3125	COG0356	it plays a direct role in the translocation of protons across the membrane
Daes_3127	COG5336	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex
Daes_3132	COG1410	methionine synthase
Daes_3132	COG0646	methionine synthase
Daes_3137	COG0698	ribose 5-phosphate isomerase
Daes_3139	COG1494	fructose-1,6-bisphosphatase
Daes_3145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Daes_3145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Daes_3146	COG2217	Heavy metal translocating P-type atpase
Daes_3147	COG0529	Catalyzes the synthesis of activated sulfate
Daes_3149	COG1111	helicase
Daes_3149	COG1205	dead DEAH box helicase
Daes_3154	COG2204	response regulator
Daes_3155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Daes_3157	COG2015	COG2015, Alkyl sulfatase and related hydrolases
Daes_3163	COG0537	adenosine 5'-monophosphoramidase activity
Daes_3165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Daes_3167	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Daes_3168	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Daes_3171	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Daes_3172	COG1132	(ABC) transporter
Daes_3174	COG0860	N-Acetylmuramoyl-L-alanine amidase
Daes_3175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Daes_3179	COG0243	molybdopterin cofactor binding
Daes_3180	COG0437	4 iron, 4 sulfur cluster binding
Daes_3186	COG1937	Protein conserved in bacteria
Daes_3187	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Daes_3188	COG1404	Belongs to the peptidase S8 family
Daes_3190	COG0071	Belongs to the small heat shock protein (HSP20) family
Daes_3192	COG2835	tetraacyldisaccharide 4'-kinase activity
Daes_3193	COG0613	PHP domain protein
Daes_3195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Daes_3196	COG0540	Belongs to the ATCase OTCase family
Daes_3197	COG0402	S-adenosylhomocysteine deaminase activity
Daes_3199	COG2608	mercury ion transmembrane transporter activity
Daes_3200	COG2197	response regulator
Daes_3203	COG0517	IMP dehydrogenase activity
Daes_3204	COG0745	RESPONSE REGULATOR receiver
Daes_3206	COG3676	manually curated
Daes_3213	COG3547	Transposase (IS116 IS110 IS902 family)
Daes_3214	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Daes_3219	COG2801	Transposase and inactivated derivatives
Daes_3220	COG2963	transposase activity
Daes_3223	COG3676	manually curated
Daes_3227	COG2172	sigma factor antagonist activity
Daes_3235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Daes_3236	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Daes_3247	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Daes_3249	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Daes_3250	COG0534	Mate efflux family protein
Daes_3256	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Daes_3257	COG3005	denitrification pathway
Daes_3258	COG1309	transcriptional regulator
Daes_3262	COG2373	Large extracellular alpha-helical protein
Daes_3263	COG4953	penicillin-binding protein 1C
Daes_3264	COG3706	GGDEF domain
Daes_3265	COG0297	glycogen (starch) synthase activity
Daes_3272	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Daes_3275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Daes_3277	COG5433	transposase activity
Daes_3278	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Daes_3278	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Daes_3282	COG0450	alkyl hydroperoxide reductase
Daes_3285	COG0589	response to stress
Daes_3286	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Daes_3290	COG3264	Mechanosensitive ion channel
Daes_3290	COG1196	nuclear chromosome segregation
Daes_3291	COG0546	phosphoglycolate phosphatase activity
Daes_3292	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Daes_3294	COG0724	RNA recognition motif
Daes_3295	COG1280	lysine exporter protein (LysE YggA)
Daes_3296	COG3676	manually curated
Daes_3298	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Daes_3299	COG0606	chelatase, subunit chli
Daes_3304	COG0583	DNA-binding transcription factor activity
Daes_3309	COG0367	asparagine synthase
Daes_3315	COG0438	transferase activity, transferring glycosyl groups
Daes_3316	COG2202	Pas domain
Daes_3316	COG2205	protein histidine kinase activity
Daes_3318	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Daes_3319	COG0187	DNA topoisomerase II activity
Daes_3321	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Daes_3323	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Daes_3324	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Daes_3325	COG0512	Glutamine amidotransferase of anthranilate synthase
Daes_3326	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Daes_3327	COG0151	Belongs to the GarS family
Daes_3331	COG3676	manually curated
Daes_3333	COG2801	Transposase and inactivated derivatives
Daes_3336	COG0674	pyruvate-flavodoxin oxidoreductase activity
Daes_3336	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Daes_3341	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine