locus-tag class description EJA96_00030 ENOG4105VTR Integrase EJA96_00055 ENOG4105C26 Dehydrogenase EJA96_00065 ENOG4108JPW Aminotransferase EJA96_00075 ENOG4108VYJ response regulator receiver protein EJA96_00085 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) EJA96_00100 ENOG4105G2Y Transcriptional regulator EJA96_00125 ENOG4108K0D peptidase, M48 EJA96_00140 ENOG4108IJ6 ABC transporter EJA96_00145 ENOG4105ECW sulfate abc transporter EJA96_00150 ENOG4108I5D sulfate abc transporter EJA96_00155 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EJA96_00165 ENOG4105BZU Histidine kinase EJA96_00180 ENOG4105CYW agmatinase EJA96_00185 ENOG4105EVZ LysR family transcriptional regulator EJA96_00190 ENOG4105BZU Histidine kinase EJA96_00195 ENOG41090KI Outer membrane porin EJA96_00215 ENOG4107RUE extracellular solute-binding protein family 1 EJA96_00220 ENOG4105CFQ glutamine synthetase EJA96_00225 ENOG4108Z86 Glutamine amidotransferase EJA96_00230 ENOG4105CFQ glutamine synthetase EJA96_00235 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EJA96_00245 ENOG4108HM4 ABC transporter EJA96_00250 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EJA96_00255 ENOG4105F38 ABC transporter, permease EJA96_00260 ENOG4105D38 putrescine abc transporter EJA96_00315 ENOG4105E5Q amino acid AbC transporter EJA96_00330 ENOG4108JQ1 Dehydrogenase EJA96_00335 ENOG4105CQB FAD linked oxidase domain protein EJA96_00340 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase EJA96_00350 ENOG4105H4F exported protein EJA96_00355 ENOG41067B5 Histone deacetylase superfamily protein EJA96_00360 ENOG4105CUB amino acid EJA96_00365 ENOG4107FKK extracellular solute-binding protein family 1 EJA96_00370 ENOG4105D38 putrescine abc transporter EJA96_00375 ENOG4105F38 ABC transporter, permease EJA96_00390 ENOG4108ZK4 sdia-regulated domain-containing protein EJA96_00395 ENOG4108MXK alkaline phosphatase isozyme conversion EJA96_00405 ENOG4105KWI UPF0339 protein EJA96_00415 ENOG4105C7B Threonine dehydratase EJA96_00455 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase EJA96_00460 ENOG4105BZU Histidine kinase EJA96_00470 ENOG4105HF0 Membrane EJA96_00505 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase EJA96_00525 ENOG4108RE9 Phosphodiesterase EJA96_00530 ENOG4105C2W permease EJA96_00540 ENOG4105DR4 Methyltransferase EJA96_00545 ENOG4107RKG DJ-1/PfpI family EJA96_00585 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EJA96_00605 ENOG4107RGH Aldehyde dehydrogenase EJA96_00630 ENOG4106H78 methyltransferase EJA96_00645 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) EJA96_00650 ENOG4105CAK Cell division ATP-binding protein ftsE EJA96_00655 ENOG4105CRP Part of the ABC transporter FtsEX involved in EJA96_00660 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EJA96_00670 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase EJA96_00680 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) EJA96_00690 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) EJA96_00695 ENOG4105D25 secreted protein EJA96_00710 ENOG4105CSA Coproporphyrinogen iii oxidase EJA96_00715 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) EJA96_00725 ENOG4105DWV Homoserine O-trans-acetylase EJA96_00735 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) EJA96_00740 ENOG4105VZ9 UPF0235 protein EJA96_00745 ENOG4108VIA integral membrane protein EJA96_00750 ENOG4105II7 pyrroline-5-carboxylate reductase EJA96_00755 ENOG4105DFA alanine racemase domain protein EJA96_00760 ENOG4105CZX twitching motility protein EJA96_00765 ENOG4105CZX twitching motility protein EJA96_00785 ENOG4105C28 cystathionine EJA96_00790 ENOG4105CD3 dihydroorotase EJA96_00820 ENOG4105D7Z glutathione synthase EJA96_00825 ENOG4108UNF response regulator EJA96_00830 ENOG4105M3Z response regulator EJA96_00835 ENOG4108ZGA chew protein EJA96_00840 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_00845 ENOG4105BZU Histidine kinase EJA96_00880 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) EJA96_00900 ENOG4105DS1 cytochrome b561 EJA96_00910 ENOG4107MHI Transcriptional regulator, MarR family EJA96_00915 ENOG4105C1P efflux transporter, rnd family, mfp subunit EJA96_00920 ENOG4105BZS acriflavin resistance protein EJA96_00925 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EJA96_00940 ENOG4105SYT Methylenetetrahydrofolate reductase EJA96_00945 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EJA96_00960 ENOG4105CNM Receptor EJA96_00970 ENOG4108R86 Transcriptional regulator EJA96_00975 ENOG4105DZC cytosine deaminase EJA96_00980 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin EJA96_00990 ENOG4107SJI Dehydrogenase EJA96_01000 ENOG4105CD3 dihydroorotase EJA96_01015 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease EJA96_01020 ENOG4105CE7 Amidase, hydantoinase carbamoylase family EJA96_01030 ENOG4105C1G acyl-Coa dehydrogenase EJA96_01035 ENOG4105ETT transcriptional Regulator, LysR family EJA96_01045 ENOG4105CJ3 phosphate transporter EJA96_01055 ENOG4107QX8 SPFH domain, Band 7 family protein EJA96_01065 ENOG4105EM2 membrane EJA96_01070 ENOG4105C1J atp-dependent rna helicase EJA96_01075 ENOG4105VEQ Cold shock protein EJA96_01080 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) EJA96_01085 ENOG4105C0R drug resistance transporter emrb qaca subfamily EJA96_01095 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EJA96_01110 ENOG4106HNH Acyl-transferase EJA96_01120 ENOG4105E3W Two component transcriptional regulator (Winged helix family EJA96_01130 ENOG4105CT7 inner membrane cred family protein EJA96_01165 ENOG4105E0K tonB-dependent siderophore receptor EJA96_01170 ENOG4108S3W Anti-feci sigma factor, fecr EJA96_01175 ENOG4108SF5 RNA Polymerase EJA96_01180 ENOG4108U78 Glutathione S-transferase EJA96_01185 ENOG41060I7 thioesterase Superfamily protein EJA96_01190 ENOG4105J7D transcriptional regulator EJA96_01195 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease EJA96_01215 ENOG4105F2Z 3-oxoadipate enol-lactonase EJA96_01240 ENOG4105FR1 rard protein EJA96_01250 ENOG4105F4R Transcriptional regulator mode EJA96_01255 ENOG4105T42 (LipO)protein EJA96_01260 ENOG4105MJ2 Competence protein EJA96_01275 ENOG4105E7W lamb ycsf family protein EJA96_01280 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein EJA96_01285 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EJA96_01315 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EJA96_01335 ENOG4105CSU acyl-Coa dehydrogenase EJA96_01340 ENOG4105CSU acyl-Coa dehydrogenase EJA96_01350 ENOG4105CSU acyl-Coa dehydrogenase EJA96_01360 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) EJA96_01370 ENOG4108UMR transcriptional regulator AsnC family EJA96_01375 ENOG4108ZGY Transcriptional regulator (AsnC family) EJA96_01380 ENOG4108UMR transcriptional regulator AsnC family EJA96_01385 ENOG4108ZGY Transcriptional regulator (AsnC family) EJA96_01390 ENOG4106P6N cytochrome d1 heme region EJA96_01395 ENOG4105Y7H Cytochrome EJA96_01400 ENOG4105W2Z cytochrome C, class I EJA96_01405 ENOG4105F64 nitrite reductase EJA96_01410 ENOG4105GMT ATPase associated with various cellular activities aaa_5 EJA96_01425 ENOG4108VKQ nitriC oxide reductase EJA96_01430 ENOG4105DSQ Nitric oxide reductase EJA96_01445 ENOG4105DS0 Transcriptional regulator, Crp Fnr family EJA96_01450 ENOG4105DND Transcriptional regulator EJA96_01455 ENOG4108RPX mosc domain containing protein EJA96_01470 ENOG41089BK Glutamine amido-transferase EJA96_01480 ENOG4108UDW Transcriptional regulator, luxr family EJA96_01490 ENOG4105CJP fad dependent oxidoreductase EJA96_01500 ENOG4105HA9 of methanol dehydrogenase type EJA96_01555 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) EJA96_01560 ENOG4105CV1 Transketolase (EC 2.2.1.1) EJA96_01570 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) EJA96_01575 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase EJA96_01595 ENOG4105D2N Aldolase EJA96_01615 ENOG4105CBX hi0933 family EJA96_01620 ENOG4108VKG metal-dependent hydrolase EJA96_01625 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 EJA96_01630 ENOG4105KAF membrAne EJA96_01635 ENOG4105E7U AraC family transcriptional regulator EJA96_01670 ENOG4107H8F EJA96_01675 ENOG4108UNC EJA96_01705 ENOG4105EKQ RNA-directed DNA polymerase EJA96_01710 ENOG4105BZU Histidine kinase EJA96_01715 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EJA96_01720 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) EJA96_01730 ENOG4105VCC 30S ribosomal protein S21 EJA96_01735 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) EJA96_01745 ENOG4107ZVW dihydroneopterin aldolase EJA96_01765 ENOG4105ED1 spovr family EJA96_01775 ENOG4105CYN Serine protein kinase EJA96_01800 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) EJA96_01805 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) EJA96_01810 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EJA96_01820 ENOG4105EKQ RNA-directed DNA polymerase EJA96_01830 ENOG4105EHM Aminoglycoside phosphotransferase EJA96_01835 ENOG4108S0S Nucleotidyl transferase EJA96_01840 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) EJA96_01855 ENOG4105WH1 Two component transcriptional regulator luxr family EJA96_01865 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EJA96_01875 ENOG4105F38 ABC transporter, permease EJA96_01885 ENOG4105DJV ribulose-phosphate 3-epimerase EJA96_01890 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EJA96_01895 ENOG4105CRQ synthase (Component I) EJA96_01905 ENOG4108XTP Transcriptional regulator EJA96_01910 ENOG4105KSC Transcriptional regulator, TraR DksA family EJA96_01995 ENOG4105NVB glycoside hydrolase, family 19 EJA96_02010 ENOG4105DDQ anthranilate synthase EJA96_02025 ENOG4107RYR Transcriptional regulator, Crp Fnr family EJA96_02030 ENOG4108UKZ OsmC family EJA96_02045 ENOG4107YU2 histidine triad (hIT) protein EJA96_02070 ENOG4108YXA Membrane EJA96_02075 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase EJA96_02095 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) EJA96_02100 ENOG4105DR5 peptidase EJA96_02105 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) EJA96_02135 ENOG4105H2K paraquat-inducible protein a EJA96_02140 ENOG4105F1S paraquat-inducible protein a EJA96_02145 ENOG4105DY2 Paraquat-inducible protein b EJA96_02150 ENOG4107QVT Binding-protein-dependent transport systems, inner membrane component EJA96_02155 ENOG4107QKW extracellular solute-binding protein family 1 EJA96_02200 ENOG410801F ribosomal-protein-alanine acetyltransferase EJA96_02210 ENOG41077A9 carbonic anhydrase EJA96_02225 ENOG41080ET plasmid maintenance system killer protein EJA96_02230 ENOG4105VDM plasmid maintenance system antidote protein, xre family EJA96_02240 ENOG4105C3G gtp-binding protein EJA96_02255 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EJA96_02265 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) EJA96_02275 ENOG4105DJQ tetratricopeptide tpr_2 repeat protein EJA96_02290 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EJA96_02295 ENOG4105D06 uba thif-type nad fad binding protein EJA96_02305 ENOG41061N2 exported protein EJA96_02310 ENOG4105CVP deoxyribo-dipyrimidine photolyase EJA96_02315 ENOG4108XDN Transcriptional regulator EJA96_02325 ENOG4108QDE fad dependent oxidoreductase EJA96_02330 ENOG4105ECP epimerase EJA96_02375 ENOG4105C2W permease EJA96_02385 ENOG4108UGV hypoxanthine phosphoribosyltransferase EJA96_02410 ENOG4105DWT malate dehydrogenase (quinone) EJA96_02445 ENOG4105KT7 mgtC SapB transporter EJA96_02450 ENOG4108RAV Conserved protein EJA96_02455 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_02460 ENOG4108K0D peptidase, M48 EJA96_02480 ENOG4108IQI permease EJA96_02490 ENOG4105C5I Dehydrogenase EJA96_02530 ENOG4107TJ9 Cytochrome EJA96_02550 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit EJA96_02555 ENOG4105DP0 ferredoxin-NADP reductase EJA96_02570 ENOG4105CH6 catalase EJA96_02590 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) EJA96_02605 ENOG4105D22 carbon starvation protein EJA96_02610 ENOG4105VCD cytoplasmic protein EJA96_02615 ENOG4105CKI cobalamin synthesis protein EJA96_02625 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) EJA96_02630 ENOG4105BZU Histidine kinase EJA96_02635 ENOG4105RJZ Transcriptional regulator EJA96_02640 ENOG4105C1P efflux transporter, rnd family, mfp subunit EJA96_02645 ENOG4105BZS acriflavin resistance protein EJA96_02650 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EJA96_02655 ENOG4105RJZ Transcriptional regulator EJA96_02665 ENOG4105C5H ABC transporter EJA96_02670 ENOG4108EE5 Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EJA96_02675 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EJA96_02700 ENOG4105D82 Glutamate dehydrogenase EJA96_02705 ENOG4105CA0 peroxidase EJA96_02720 ENOG410756H nucleotidyltransferase EJA96_02725 ENOG4105E0Y RtcB Protein EJA96_02740 ENOG4105CYB regulatoR EJA96_02765 ENOG4105DAN ATP-dependent protease EJA96_02775 ENOG4108TEB UPF0114 protein EJA96_02785 ENOG4108V1T peptidylprolyl cis-trans isomerase EJA96_02800 ENOG4105EAH synthase EJA96_02825 ENOG4108RH0 Crea protein EJA96_02835 ENOG4105CJR Integral membrane protein (MviN EJA96_02840 ENOG4105DTN riboflavin biosynthesis protein ribF EJA96_02845 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) EJA96_02855 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase EJA96_02865 ENOG4106855 Competence protein EJA96_02905 ENOG4105MWK D-amino acid dehydrogenase, small subunit EJA96_02910 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_02915 ENOG4107TUY Histidine kinase EJA96_02925 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane EJA96_02930 ENOG4105C34 Pseudouridine synthase EJA96_02935 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase EJA96_02940 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EJA96_02985 ENOG4105VV5 Plasmid stabilization system EJA96_02990 ENOG4105X54 addiction module antidote protein EJA96_03100 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation EJA96_03250 ENOG4107QHF type ii secretion system protein e EJA96_03265 ENOG4107QHF type ii secretion system protein e EJA96_03290 ENOG4105VUH addiction module killer protein EJA96_03295 ENOG4105YES addiction module antidote protein EJA96_03305 ENOG4105C0D helicase EJA96_03440 ENOG4105CDU Replicative dna helicase EJA96_03480 ENOG4107QJE Chromosome Partitioning Protein EJA96_03490 ENOG4108D1Y Polypeptide-transport-associated domain protein, ShlB-type EJA96_03495 ENOG4105D6Z AFG1 family ATPase EJA96_03500 ENOG4105CEP NADH dehydrogenase EJA96_03545 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) EJA96_03550 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) EJA96_03560 ENOG4107QHF type ii secretion system protein e EJA96_03565 ENOG4105KHS type IV fimbrial pilin protein EJA96_03580 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase EJA96_03600 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_03605 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) EJA96_03615 ENOG4105DIJ Phosphoethanolamine transferase EJA96_03630 ENOG4108ESX Receptor EJA96_03645 ENOG4105E7W lamb ycsf family protein EJA96_03655 ENOG4107R7A Allophanate hydrolase subunit 2 EJA96_03660 ENOG4105EW9 transcriptional regulator AsnC family EJA96_03665 ENOG4108NIW Leucine export protein LeuE EJA96_03670 ENOG4108JQ7 (ABC) transporter EJA96_03675 ENOG4105C3U ABC transporter EJA96_03680 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EJA96_03685 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EJA96_03690 ENOG4105DEF Extracellular solute-binding protein, family 5 EJA96_03705 ENOG4105DEF Extracellular solute-binding protein, family 5 EJA96_03720 ENOG4105DEF Extracellular solute-binding protein, family 5 EJA96_03725 ENOG4105DEF Extracellular solute-binding protein, family 5 EJA96_03735 ENOG4105TX3 Histidine kinase EJA96_03740 ENOG4108UYB regulatoR EJA96_03745 ENOG4105EDV vault protein EJA96_03750 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) EJA96_03755 ENOG4108QJJ Protein of unknown function (DUF1175) EJA96_03760 ENOG4107S52 alpha-2-macroglobulin domain protein EJA96_03765 ENOG41081SK signal peptide protein EJA96_03770 ENOG4105EDV vault protein EJA96_03775 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase EJA96_03780 ENOG4105K6T rare lipoprotein A EJA96_03800 ENOG4105DFF Rod shape-determining protein mreb EJA96_03815 ENOG4108Z03 MAF-like protein EJA96_03820 ENOG4105C03 ribonuclease EJA96_03835 ENOG4105D1U peptidase U62 modulator of DNA gyrase EJA96_03840 ENOG4105N42 UPF0307 protein EJA96_03845 ENOG4105CMS peptidase U62, modulator of DNA gyrase EJA96_03855 ENOG4105C9Q fumarate hydratase class II EJA96_03865 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EJA96_03875 ENOG41080Z8 PHOSPHOCARRIER protein EJA96_03880 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) EJA96_03885 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN EJA96_03890 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA EJA96_03895 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EJA96_03900 ENOG4108IUZ ABC transporter EJA96_03915 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase EJA96_03920 ENOG4105C2X Arabinose 5-phosphate isomerase EJA96_03925 ENOG4105DHJ ABC, transporter EJA96_03930 ENOG4105CY3 ABC transporter, permease EJA96_03935 ENOG4107PE3 Mammalian cell entry related domain protein EJA96_03965 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) EJA96_03970 ENOG4105CIH Imidazole acetol-phosphate transaminase EJA96_03975 ENOG4105C0H protease EJA96_03980 ENOG4107QNR UPF0135 protein EJA96_03985 ENOG4105CVE Lytic murein transglycosylase EJA96_03995 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) EJA96_04005 ENOG4105DHZ alpha beta EJA96_04010 ENOG4105C31 Tryptophanyl-tRNA synthetase EJA96_04015 ENOG4105D6Z AFG1 family ATPase EJA96_04030 ENOG4105C1G acyl-Coa dehydrogenase EJA96_04035 ENOG4105CPC Aldo Keto reductase EJA96_04050 ENOG4108R5F Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) EJA96_04055 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) EJA96_04060 ENOG4105EIX cytochrome c1 EJA96_04065 ENOG4107MKT Stringent starvation protein a EJA96_04070 ENOG4105KB2 stringent starvation protein b EJA96_04075 ENOG4105W4M Transport-associated protein EJA96_04085 ENOG41082RQ UPF0102 protein EJA96_04090 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) EJA96_04095 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) EJA96_04120 ENOG4105CJN penicillin-binding protein EJA96_04125 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) EJA96_04130 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) EJA96_04140 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) EJA96_04145 ENOG4105CNI cell division protein FtsW EJA96_04160 ENOG4105CPF Cell wall formation (By similarity) EJA96_04165 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) EJA96_04170 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) EJA96_04175 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) EJA96_04190 ENOG4105E4C Lytic transglycosylase catalytic EJA96_04205 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) EJA96_04215 ENOG4105M6F mutator MutT protein EJA96_04220 ENOG4108WBT adenosyltransferase EJA96_04230 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) EJA96_04235 ENOG4108VYJ response regulator receiver protein EJA96_04245 ENOG4105D64 Mechanosensitive ion channel EJA96_04280 ENOG4105FS0 cytoplasmic membrane protein EJA96_04315 ENOG4105ETX regulatoR EJA96_04320 ENOG4106F60 Histidine kinase EJA96_04330 ENOG4105FQR PH-inducible protein involved in stress response EJA96_04340 ENOG4107RH7 Nicotinate phosphoribosyltransferase EJA96_04345 ENOG4105BZS acriflavin resistance protein EJA96_04350 ENOG410624X efflux transporter, rnd family, mfp subunit EJA96_04375 ENOG4108V0P LemA family EJA96_04390 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EJA96_04415 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase EJA96_04430 ENOG4105XFK Ferrous iron transport protein A EJA96_04440 ENOG41060N5 May function as a transcriptional regulator that controls feoABC expression (By similarity) EJA96_04445 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EJA96_04450 ENOG4105F27 Major Facilitator EJA96_04490 ENOG4105FQP Beta-lactamase EJA96_04505 ENOG4105CH2 amidohydrolase EJA96_04510 ENOG4105CSH Transporter EJA96_04530 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) EJA96_04545 ENOG4107R7Y intracellular protease Pfpi family EJA96_04555 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) EJA96_04560 ENOG4107GFK fumarate EJA96_04565 ENOG4105BZU Histidine kinase EJA96_04575 ENOG4105E39 Enoyl-CoA hydratase EJA96_04580 ENOG4105CA9 Pyruvate kinase EJA96_04585 ENOG4105Q9Y Universal stress protein EJA96_04615 ENOG4105C7R Atpase associated with various cellular activities aaa_3 EJA96_04645 ENOG4105CJB Exodeoxyribonuclease I EJA96_04685 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_04690 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_04695 ENOG4105D7A ATP-binding protein EJA96_04700 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_04755 ENOG4108ZXC Two component transcriptional regulator, luxr family EJA96_04775 ENOG4105CJ3 phosphate transporter EJA96_04785 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_04800 ENOG410631K Membrane EJA96_04805 ENOG4108KMH lipoate-protein ligase a EJA96_04820 ENOG4107QYX exodeoxyribonuclease v alpha EJA96_04825 ENOG4105EYH Exonuclease EJA96_04830 ENOG4107RH8 nuclease SbcCD subunit D EJA96_04860 ENOG4105C0B DNA polymerase III (alpha subunit) EJA96_04875 ENOG4108YNN Heme oxygenase EJA96_04900 ENOG4108WWZ General secretion pathway protein J EJA96_04915 ENOG4105X5Z General secretion pathway protein I EJA96_04920 ENOG4108VAU general secretion pathway protein G EJA96_04940 ENOG4105GVR general secretion pathway protein D EJA96_04945 ENOG4107QHF type ii secretion system protein e EJA96_04970 ENOG4105D5K Hemolysin activator protein EJA96_04980 ENOG4105SG9 biopolymer transport protein, ExbD EJA96_05005 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EJA96_05015 ENOG4107RSM transcriptional regulator EJA96_05030 ENOG4105CSH Transporter EJA96_05035 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) EJA96_05045 ENOG4105K64 Glycosyl transferase, family 2 EJA96_05050 ENOG4105EQK -acetyltransferase EJA96_05060 ENOG4105EGI Transcriptional regulator EJA96_05150 ENOG4105MQ5 zona occludens toxin EJA96_05160 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EJA96_05180 ENOG4108YI3 3-hydroxyacyl-CoA-acyl carrier protein transferase EJA96_05195 ENOG4105I08 Pseudouridine synthase EJA96_05240 ENOG4105EUZ Beta-lactamase domain protein EJA96_05245 ENOG4108RYK Nad-dependent epimerase dehydratase EJA96_05275 ENOG4105C26 Dehydrogenase EJA96_05285 ENOG4107RBI VanW family EJA96_05315 ENOG4105EPF Outer membrane porin EJA96_05335 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) EJA96_05340 ENOG4105Y75 tpr repeat protein EJA96_05350 ENOG4108IYU L-aspartate oxidase EJA96_05355 ENOG4105EMN RNA polymerase sigma factor EJA96_05360 ENOG41069E1 anti sigma-E protein RseA EJA96_05365 ENOG4105VQK sigma E regulatory protein, MucB RseB EJA96_05375 ENOG4105C0H protease EJA96_05385 ENOG4105C3F Signal peptidase i EJA96_05440 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) EJA96_05450 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) EJA96_05455 ENOG4105C26 Dehydrogenase EJA96_05460 ENOG4105CK7 Sodium proline symporter EJA96_05465 ENOG4105ETT transcriptional Regulator, LysR family EJA96_05475 ENOG4105KPY Small multidrug resistance protein EJA96_05495 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) EJA96_05500 ENOG4105C85 amino acid EJA96_05515 ENOG4105DXD 2-methylcitrate dehydratase EJA96_05520 ENOG4105C7F AcnD-accessory protein PrpF EJA96_05525 ENOG4108I0Z Aconitate hydratase EJA96_05530 ENOG4105BZN citrate synthase EJA96_05535 ENOG4105CR4 methylisocitrate lyase EJA96_05540 ENOG4105DRR Transcriptional regulator, GntR family EJA96_05545 ENOG4107UX3 phosphatidylethanolamine N-methyltransferase EJA96_05550 ENOG4105C0D helicase EJA96_05575 ENOG4105CV8 reductase EJA96_05590 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase EJA96_05600 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) EJA96_05605 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EJA96_05630 ENOG4105DUM transcriptional regulator, lysR family EJA96_05635 ENOG4105DUM transcriptional regulator, lysR family EJA96_05700 ENOG4108IG5 Transcriptional regulator EJA96_05705 ENOG4106HB6 Alpha beta hydrolase EJA96_05715 ENOG4108ZX5 transcriptional regulator EJA96_05720 ENOG4105C5X domain protein EJA96_05725 ENOG4108ZG0 Ompa motb domain protein EJA96_05730 ENOG4106HNH Acyl-transferase EJA96_05735 ENOG4105C6K Malic enzyme EJA96_05750 ENOG4108YZY peptidylprolyl cis-trans isomerase EJA96_05755 ENOG4108V06 Glutathione peroxidase EJA96_05760 ENOG4108WUH Transcriptional regulator, TetR family EJA96_05770 ENOG4108RMV DegV Family EJA96_05785 ENOG4105HSS phospholipase C EJA96_05790 ENOG4107R72 Ceramidase EJA96_05800 ENOG4105BZU Histidine kinase EJA96_05805 ENOG4105D3R alkyl hydroperoxide reductase EJA96_05810 ENOG4105C3M thioredoxin reductase EJA96_05835 ENOG4105C9Q fumarate hydratase class II EJA96_05850 ENOG4105M85 Bola protein EJA96_05865 ENOG4105BZ1 (ABC) transporter EJA96_05870 ENOG4105BZU Histidine kinase EJA96_05900 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase EJA96_05905 ENOG4105C85 amino acid EJA96_05910 ENOG41069B0 Membrane-bound lysozyme-inhibitor of c-type lysozyme EJA96_05915 ENOG4108YZN class I peptide chain release factor EJA96_05920 ENOG41061WM D-Alanyl-D-Alanine EJA96_05935 ENOG4105MIR Phenylalanine 4-monooxygenase EJA96_05940 ENOG4108JU8 Transcriptional regulator EJA96_05965 ENOG4105EJC lysr family transcriptional regulator EJA96_05975 ENOG4108M9J MaoC like domain protein EJA96_05980 ENOG4105C1G acyl-Coa dehydrogenase EJA96_05985 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase EJA96_06000 ENOG4105CI0 Citrate lyase EJA96_06005 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit EJA96_06010 ENOG410835K Tripartite ATP-Independent Periplasmic transporter DctQ EJA96_06015 ENOG4105CG6 trap dicarboxylate transporter dctm subunit EJA96_06020 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EJA96_06025 ENOG4105E89 ABC transporter EJA96_06030 ENOG4105DSP amino acid AbC transporter EJA96_06045 ENOG4108JEH abc transporter atp-binding protein EJA96_06050 ENOG4105ECQ AraC Family Transcriptional Regulator EJA96_06060 ENOG4105C8Y Acetylornithine aminotransferase EJA96_06065 ENOG4108T2Z Arginine EJA96_06075 ENOG4105C26 Dehydrogenase EJA96_06095 ENOG4105C5W Aldolase EJA96_06100 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) EJA96_06105 ENOG4105CFH Aspartokinase EJA96_06130 ENOG4108XTP Transcriptional regulator EJA96_06165 ENOG4105CJW magnesium transporter EJA96_06175 ENOG4108W15 Protein of unknown function (DUF1456) EJA96_06180 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) EJA96_06195 ENOG4108VKM cytochrome b561 EJA96_06230 ENOG4105E68 Sulfatase EJA96_06245 ENOG4105C5I Dehydrogenase EJA96_06250 ENOG4105BZU Histidine kinase EJA96_06260 ENOG410804D Sensor Signal Transduction Histidine Kinase EJA96_06265 ENOG4107RNH Outer membrane receptor FepA EJA96_06270 ENOG4105C6T cysteine synthase EJA96_06280 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EJA96_06285 ENOG4105DXN mazG family EJA96_06295 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme EJA96_06335 ENOG4108V3E phosphoribosylglycinamide formyltransferase EJA96_06355 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) EJA96_06365 ENOG4105CS1 NAD(P)H quinone oxidoreductase EJA96_06390 ENOG4105R2R Thioredoxin EJA96_06395 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 EJA96_06415 ENOG4105J5J Outer membrane porin EJA96_06430 ENOG4105VEQ Cold shock protein EJA96_06445 ENOG4105CDY transcriptional regulatory protein EJA96_06465 ENOG4107YD3 Thioesterase EJA96_06470 ENOG4105E02 MotA TolQ exbB proton channel EJA96_06475 ENOG4105M8F Biopolymer transport protein exbD tolR EJA96_06485 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) EJA96_06490 ENOG4105KCK Peptidoglycan-associated lipoprotein EJA96_06495 ENOG4105UFD tol-pal system protein YbgF EJA96_06500 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) EJA96_06530 ENOG4105MSY salicylate hydroxylase EJA96_06540 ENOG4108NNI Beta-lactamase domain-containing protein EJA96_06545 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) EJA96_06555 ENOG4108S8N class II Aldolase EJA96_06570 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr EJA96_06580 ENOG4105CKD glutathione-regulated potassium-efflux system protein EJA96_06665 ENOG4108AF8 Chaperone EJA96_06670 ENOG4105CW0 outer membrane usher protein EJA96_06675 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EJA96_06680 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EJA96_06690 ENOG4108MJ1 3-oxoacyl-(ACP) synthase EJA96_06695 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) EJA96_06700 ENOG4105R2E Metallo-beta-lactamase superfamily EJA96_06705 ENOG4105CRQ synthase (Component I) EJA96_06710 ENOG4105DDQ anthranilate synthase EJA96_06715 ENOG4105DUM transcriptional regulator, lysR family EJA96_06725 ENOG4105ERG peptidase m48, ste24p EJA96_06730 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) EJA96_06740 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EJA96_06750 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EJA96_06755 ENOG4105GJM (LipO)protein EJA96_06760 ENOG4105CY0 Metallo-Beta-Lactamase EJA96_06775 ENOG4107QJZ Glycosyl transferase, family 2 EJA96_06790 ENOG4105CHU acetyl-coa acetyltransferase EJA96_06800 ENOG410900P UPF0336 protein EJA96_06805 ENOG4107RGD Major Facilitator superfamily EJA96_06815 ENOG4105D2B acyl-CoA dehydrogenase EJA96_06820 ENOG4105E39 Enoyl-CoA hydratase EJA96_06825 ENOG4105CC9 acyl-Coa dehydrogenase EJA96_06830 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr EJA96_06835 ENOG4105EA8 2-Nitropropane dioxygenase EJA96_06840 ENOG4105EPF Outer membrane porin EJA96_06855 ENOG4105C26 Dehydrogenase EJA96_06860 ENOG4105CJP fad dependent oxidoreductase EJA96_06875 ENOG4105CGY Dna recombination protein EJA96_06880 ENOG4105CUJ penicillin amidase EJA96_06885 ENOG4105CYM Glutathione S-transferase EJA96_06890 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving EJA96_06905 ENOG4105EN6 Membrane EJA96_06915 ENOG4105K5B UPF0225 protein EJA96_06925 ENOG4105CDV Ompa motb domain protein EJA96_06945 ENOG4105DVT helicase EJA96_06960 ENOG4105F37 PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6 EJA96_06970 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR EJA96_06975 ENOG4105C6Z Gluconate EJA96_06980 ENOG4105BZW Glycerate kinase EJA96_06990 ENOG4108XTF Outer Membrane Lipoprotein EJA96_07000 ENOG4108ZE9 Monovalent cation H antiporter subunit C EJA96_07005 ENOG4107R4Z monovalent cation h antiporter subunit d EJA96_07010 ENOG4105SC1 monovalent cation H antiporter subunit E EJA96_07015 ENOG4105W4C monovalent cation H antiporter subunit F EJA96_07030 ENOG4105C6T cysteine synthase EJA96_07050 ENOG4105K78 MarR family Transcriptional regulator EJA96_07060 ENOG4105JQN Transcriptional regulator EJA96_07065 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) EJA96_07075 ENOG4108IV0 ABC, transporter EJA96_07080 ENOG4105C0Z ABC transporter EJA96_07085 ENOG4105CF8 branched-chain amino acid ABC transporter, permease EJA96_07090 ENOG4105C32 Amino acid ABC transporter (Permease) EJA96_07095 ENOG4105CP9 extracellular ligand-binding receptor EJA96_07115 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) EJA96_07120 ENOG4108ZC9 flagellar basal-body rod protein flgc EJA96_07125 ENOG4105W00 Flagellar hook capping protein EJA96_07130 ENOG4105BZE flagellar hook protein, FlgE EJA96_07135 ENOG4108KPB Flagellar basal-body rod protein FlgF EJA96_07140 ENOG4105CGA flagellar basal-body rod protein FlgG EJA96_07155 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj EJA96_07160 ENOG4105E1Q flagellar hook-associated protein EJA96_07165 ENOG4105DTJ flagellar hook-associated protein EJA96_07180 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) EJA96_07185 ENOG4105CHR reductase EJA96_07235 ENOG4105MQ3 flagellar protein FliS EJA96_07245 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_07250 ENOG4105BZU Histidine kinase EJA96_07255 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_07265 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) EJA96_07270 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) EJA96_07280 ENOG4108JIR Flagellum-specific ATP synthase EJA96_07285 ENOG4105GSA Flagellar export protein flij EJA96_07305 ENOG4105R1U AraC Family Transcriptional Regulator EJA96_07320 ENOG4105D8V Glucose sorbosone dehydrogenase EJA96_07325 ENOG4105VYA Uncharacterized conserved protein (DUF2132) EJA96_07340 ENOG4105BZ1 (ABC) transporter EJA96_07370 ENOG41090EK ompa motb domain protein EJA96_07375 ENOG4108KHX Diguanylate cyclase EJA96_07380 ENOG4108WS1 EJA96_07385 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) EJA96_07400 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein EJA96_07405 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) EJA96_07415 ENOG4108FN7 Aldo keto reductase EJA96_07420 ENOG410642W LysR family Transcriptional regulator EJA96_07425 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) EJA96_07460 ENOG4107WYG Transcriptional regulator, luxr family EJA96_07480 ENOG4105S0E allantoin catabolism protein EJA96_07485 ENOG4105EGI Transcriptional regulator EJA96_07495 ENOG4108RXW HAD-superfamily subfamily IB hydrolase EJA96_07505 ENOG4105EVZ LysR family transcriptional regulator EJA96_07510 ENOG4105C0A alcohol dehydrogenase EJA96_07515 ENOG4105CUB amino acid EJA96_07535 ENOG4108MA7 Inherit from COG: YD repeat protein EJA96_07535 ENOG4108MA7 Inherit from COG: YD repeat protein EJA96_07555 ENOG4108UK5 Transposase EJA96_07560 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EJA96_07565 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EJA96_07570 ENOG4107EXC regulatoR EJA96_07575 ENOG4105JJR Histidine kinase EJA96_07580 ENOG4105VEQ Cold shock protein EJA96_07590 ENOG4105DHI Methyltransferase EJA96_07605 ENOG4105CUZ uba thif-type nad fad binding protein EJA96_07610 ENOG4108TSE Transferase EJA96_07630 ENOG4107EFQ arachidonate 15-lipoxygenase EJA96_07635 ENOG4108ZCF integral membrane protein EJA96_07640 ENOG4105CVE Lytic murein transglycosylase EJA96_07660 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase EJA96_07680 ENOG4105XJC Two component transcriptional regulator (Winged helix family EJA96_07690 ENOG4105BZU Histidine kinase EJA96_07710 ENOG4105ETT transcriptional Regulator, LysR family EJA96_07715 ENOG4105CYM Glutathione S-transferase EJA96_07725 ENOG4105C1G acyl-Coa dehydrogenase EJA96_07730 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F EJA96_07740 ENOG41069YE inner membrane protein yohC EJA96_07755 ENOG4108R3E Dna-3-methyladenine glycosylase i EJA96_07760 ENOG4105D5Q Arginine ornithine antiporter EJA96_07765 ENOG4106V2I dimethylaminohydrolase EJA96_07770 ENOG4108JUB Transcriptional regulator EJA96_07775 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) EJA96_07780 ENOG4108QBX (LipO)protein EJA96_07785 ENOG4105K4H Nlp p60 protein EJA96_07795 ENOG4105CC0 LysR family Transcriptional regulator EJA96_07800 ENOG4105CHJ isochorismatase hydrolase EJA96_07810 ENOG4108YYH Nadph-dependent fmn reductase EJA96_07815 ENOG4105EUB pirin domain protein EJA96_07825 ENOG4105CKD glutathione-regulated potassium-efflux system protein EJA96_07840 ENOG4105C2I pirin domain protein EJA96_07850 ENOG4105E5W Transporter EJA96_07865 ENOG4105CEY Amp-dependent synthetase and ligase EJA96_07875 ENOG4107SDT Homocitrate synthase EJA96_07900 ENOG4105CA3 membrane-bound lytic murein transglycosylase EJA96_07910 ENOG4105ETT transcriptional Regulator, LysR family EJA96_07930 ENOG4105DWY Agmatine deiminase EJA96_07935 ENOG4105DYS nad(p)h dehydrogenase (quinone) EJA96_07955 ENOG4105R1U AraC Family Transcriptional Regulator EJA96_08025 ENOG4105CQZ Histidine kinase EJA96_08045 ENOG4107QZV Type I secretion membrane fusion protein EJA96_08050 ENOG4105DFG type I secretion outer membrane protein EJA96_08065 ENOG4105QNJ serralysin (EC 3.4.24.40) EJA96_08070 ENOG41065N1 inhibitor EJA96_08080 ENOG4105DG4 malate L-lactate dehydrogenase EJA96_08090 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EJA96_08095 ENOG4105CTU Proline racemase EJA96_08100 ENOG4105CDA abc transporter atp-binding protein EJA96_08110 ENOG4105DRP amino acid AbC transporter EJA96_08170 ENOG4105CTU Proline racemase EJA96_08175 ENOG4105G3Z GntR family transcriptional regulator EJA96_08185 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) EJA96_08190 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase EJA96_08195 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) EJA96_08200 ENOG4105E7Q Cob(II)yrinic acid a,c-diamide reductase EJA96_08210 ENOG4105EFT decarboxylase EJA96_08220 ENOG4108YZT Adenosylcobinamide kinase EJA96_08235 ENOG4105GN9 Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) EJA96_08250 ENOG4105CSU acyl-Coa dehydrogenase EJA96_08270 ENOG4105ISI outer membrane protein, OMPP1 FadL TodX family EJA96_08290 ENOG4105KHC sulfurtransferase EJA96_08310 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase EJA96_08315 ENOG4105PGM cation diffusion facilitator family transporter EJA96_08325 ENOG4108ZZ3 UPF0260 protein EJA96_08330 ENOG410904A RNA polymerase EJA96_08335 ENOG4108S3W Anti-feci sigma factor, fecr EJA96_08345 ENOG4105C3F Signal peptidase i EJA96_08365 ENOG4105E7A Glutamine amidotransferase EJA96_08375 ENOG4105DUM transcriptional regulator, lysR family EJA96_08390 ENOG4105JQN Transcriptional regulator EJA96_08420 ENOG4105E2S oxidase) subunit II EJA96_08425 ENOG4105BZ9 Cytochrome C oxidase, subunit I EJA96_08430 ENOG4105CCU oxidase (Subunit III) EJA96_08435 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) EJA96_08445 ENOG4108ESX Receptor EJA96_08460 ENOG4108VSZ Inherit from COG: ketosteroid isomerase-like protein EJA96_08465 ENOG4105C7B Threonine dehydratase EJA96_08475 ENOG410642W LysR family Transcriptional regulator EJA96_08485 ENOG4105E1F short-chain dehydrogenase reductase EJA96_08490 ENOG4105EE5 Membrane protein terC EJA96_08515 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_08520 ENOG4105CQZ Histidine kinase EJA96_08525 ENOG4105HDK L-asparaginase EJA96_08530 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) EJA96_08535 ENOG4105CDA abc transporter atp-binding protein EJA96_08540 ENOG4105DRP amino acid AbC transporter EJA96_08545 ENOG4105EAD ABC transporter EJA96_08550 ENOG4107RP9 extracellular solute-binding protein, family 3 EJA96_08560 ENOG4105EWI Short-chain dehydrogenase reductase Sdr EJA96_08565 ENOG4105D7Z glutathione synthase EJA96_08575 ENOG4108Q9V regulatoR EJA96_08585 ENOG4105GRZ Ycii-related protein EJA96_08600 ENOG4105EQ0 Major Facilitator superfamily EJA96_08610 ENOG4105GRZ Ycii-related protein EJA96_08625 ENOG4108UIN ybak prolyl-trna synthetase associated region EJA96_08640 ENOG4107AQZ Membrane EJA96_08690 ENOG4107YPT transcriptional regulator EJA96_08695 ENOG4105CJ0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity) EJA96_08705 ENOG4105WCN acetyltransferase EJA96_08715 ENOG4105EMU Dehydrogenase EJA96_08720 ENOG4105CF7 AraC family transcriptional regulator EJA96_08730 ENOG4105GVR general secretion pathway protein D EJA96_08740 ENOG4105CMR udp-glucose 4-epimerase EJA96_08750 ENOG4105EY8 ABC transporter EJA96_08765 ENOG4107TAE Glycosyl transferase (Group 1 EJA96_08770 ENOG4105K64 Glycosyl transferase, family 2 EJA96_08775 ENOG4105CG5 Glycosyl transferase (Group 1 EJA96_08785 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) EJA96_08800 ENOG4105BZU Histidine kinase EJA96_08820 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) EJA96_08835 ENOG4105EC0 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity) EJA96_08855 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) EJA96_08870 ENOG41067B5 Histone deacetylase superfamily protein EJA96_08875 ENOG4107RUE extracellular solute-binding protein family 1 EJA96_08880 ENOG4105FR1 rard protein EJA96_08890 ENOG4105EGI Transcriptional regulator EJA96_08900 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) EJA96_08930 ENOG4105CYW agmatinase EJA96_08935 ENOG4105EVZ LysR family transcriptional regulator EJA96_08940 ENOG4107SDU Methyl-accepting chemotaxis EJA96_08965 ENOG4105K5X acetyltransferase EJA96_08975 ENOG4105VJY transcriptional regulator EJA96_08985 ENOG4105NNS Autoinducer synthesis protein EJA96_08990 ENOG4105BZU Histidine kinase EJA96_09005 ENOG4105BZS acriflavin resistance protein EJA96_09020 ENOG4105WD1 Membrane EJA96_09040 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) EJA96_09045 ENOG4105DD5 Flagellar motor switch protein EJA96_09055 ENOG4105CN7 Flagellar biosynthetic protein FliP EJA96_09060 ENOG4105VS8 Flagellar biosynthetic protein fliq EJA96_09065 ENOG4105D19 Role in flagellar biosynthesis (By similarity) EJA96_09070 ENOG4105D00 flagellar biosynthetic protein flhB EJA96_09080 ENOG4105HA9 of methanol dehydrogenase type EJA96_09085 ENOG4105D7B Flagellar biosynthesis protein flha EJA96_09090 ENOG4105FZW flagellar biosynthesis regulator FlhF EJA96_09100 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EJA96_09105 ENOG4108VYJ response regulator receiver protein EJA96_09120 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) EJA96_09125 ENOG4105E14 MotA TolQ exbB proton channel EJA96_09130 ENOG4105ER2 Ompa motb domain protein EJA96_09135 ENOG4107QJE Chromosome Partitioning Protein EJA96_09145 ENOG4108V3W Chemotaxis protein, CheW EJA96_09195 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) EJA96_09200 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) EJA96_09205 ENOG41060IM Heme exporter protein EJA96_09210 ENOG41067VX Heme exporter protein EJA96_09220 ENOG4105DA4 cytochrome c-type biogenesis protein EJA96_09225 ENOG4107QX9 Thiol disulfide interChange protein EJA96_09230 ENOG4105KWW Biogenesis protein EJA96_09235 ENOG4108M1T Cytochrome c-type biogenesis protein EJA96_09245 ENOG4105WH1 Two component transcriptional regulator luxr family EJA96_09260 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) EJA96_09270 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein EJA96_09275 ENOG4105E98 transcriptional regulator DeoR family EJA96_09280 ENOG4105ENY Ethanolamine utilization protein eutH EJA96_09290 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EJA96_09305 ENOG4105EYW Ion transport protein EJA96_09315 ENOG4105CA9 Pyruvate kinase EJA96_09325 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EJA96_09330 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) EJA96_09335 ENOG41060W2 glyoxylate carboligase EJA96_09345 ENOG4108R86 Transcriptional regulator EJA96_09350 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EJA96_09360 ENOG4105C2W permease EJA96_09380 ENOG4105CS6 Rhs element vgr protein EJA96_09385 ENOG4108WC9 type VI secretion system effector, hcp1 family EJA96_09415 ENOG4105VT2 5-hydroxyisourate hydrolase EJA96_09420 ENOG4105C7N Xanthine uracil vitamin C permease EJA96_09435 ENOG4107QUY Guanine deaminase EJA96_09455 ENOG4105EEF Alkane 1-monooxygenase EJA96_09500 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) EJA96_09510 ENOG4105C1G acyl-Coa dehydrogenase EJA96_09515 ENOG4106611 bacteriocin immunity EJA96_09525 ENOG4107RN6 Monooxygenase EJA96_09540 ENOG41090TI Catalyzes the excretion of spermidine (By similarity) EJA96_09555 ENOG4105DS0 Transcriptional regulator, Crp Fnr family EJA96_09565 ENOG4105D4P Coproporphyrinogen iii oxidase EJA96_09590 ENOG4105C58 cytochrome c oxidase accessory protein ccog EJA96_09600 ENOG4105D6P C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity) EJA96_09615 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i EJA96_09620 ENOG4105D6P C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity) EJA96_09635 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i EJA96_09650 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor EJA96_09655 ENOG4107QM5 aconitate hydratase EJA96_09670 ENOG4105CJP fad dependent oxidoreductase EJA96_09675 ENOG4105CFQ glutamine synthetase EJA96_09685 ENOG4105CJP fad dependent oxidoreductase EJA96_09690 ENOG4105M4H endoribonuclease L-psp EJA96_09705 ENOG4105DUM transcriptional regulator, lysR family EJA96_09720 ENOG4108XC3 NADH ubiquinone oxidoreductase EJA96_09755 ENOG4105VV6 START domain-containing protein EJA96_09765 ENOG4105DFS Conserved Protein EJA96_09770 ENOG4108YGG dna repair protein EJA96_09880 ENOG4105DHJ ABC, transporter EJA96_09885 ENOG4105CY3 ABC transporter, permease EJA96_09910 ENOG41062JF Transcriptional regulator EJA96_09920 ENOG4106NZI LysR family Transcriptional regulator EJA96_09930 ENOG4105KPY Small multidrug resistance protein EJA96_10015 ENOG4105BZN citrate synthase EJA96_10020 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit EJA96_10025 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein EJA96_10030 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) EJA96_10035 ENOG4105E33 succinate dehydrogenase EJA96_10040 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 EJA96_10045 ENOG4105C7S Dehydrogenase EJA96_10050 ENOG4107QN2 dihydrolipoyl dehydrogenase EJA96_10060 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha EJA96_10065 ENOG4105CWM branched-chain amino acid transport system II carrier protein EJA96_10095 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) EJA96_10110 ENOG4105R1U AraC Family Transcriptional Regulator EJA96_10120 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding EJA96_10130 ENOG4108VHT MarR family transcriptional regulator EJA96_10170 ENOG4105BZU Histidine kinase EJA96_10180 ENOG4107RNH Outer membrane receptor FepA EJA96_10200 ENOG4108IQE Amp-dependent synthetase and ligase EJA96_10205 ENOG4105KA0 thioesterase Superfamily protein EJA96_10230 ENOG4105CYM Glutathione S-transferase EJA96_10240 ENOG4105IPI Membrane EJA96_10245 ENOG4105DJ2 Major Facilitator Superfamily EJA96_10250 ENOG41073TP transcriptional regulator EJA96_10260 ENOG4105E39 Enoyl-CoA hydratase EJA96_10270 ENOG4105C1G acyl-Coa dehydrogenase EJA96_10280 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EJA96_10285 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EJA96_10300 ENOG4105EEX Two component transcriptional regulator (Winged helix family EJA96_10325 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) EJA96_10340 ENOG4105EW6 flavin reductase domain protein, FMN-binding EJA96_10350 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_10365 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein EJA96_10380 ENOG4105DKK Benzoate EJA96_10395 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EJA96_10410 ENOG4105CNA YD repeat protein EJA96_10425 ENOG4108WC9 type VI secretion system effector, hcp1 family EJA96_10465 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EJA96_10470 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_10505 ENOG4108ZF3 Phosphatase EJA96_10525 ENOG4105EUJ GTP cyclohydrolase i EJA96_10545 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) EJA96_10570 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) EJA96_10595 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) EJA96_10715 ENOG4106V6P Exoenzyme S synthesis protein C EJA96_10730 ENOG4108KB1 transcriptional regulator, arac family EJA96_10760 ENOG41066XE Type III export protein EJA96_10765 ENOG41070MY type iii secretion EJA96_10795 ENOG4107QK4 glycoside hydrolase, family 3 domain protein EJA96_10800 ENOG4105BZU Histidine kinase EJA96_10850 ENOG4105CHU acetyl-coa acetyltransferase EJA96_10860 ENOG4105EQ2 LysR family Transcriptional regulator EJA96_10865 ENOG4105CPC Aldo Keto reductase EJA96_10880 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EJA96_10920 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EJA96_10935 ENOG41084M5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) EJA96_10945 ENOG4107R11 Transcriptional regulator EJA96_10960 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein EJA96_10965 ENOG4105CRQ synthase (Component I) EJA96_10970 ENOG41061ZR Transcriptional regulator EJA96_10975 ENOG41061ZR Transcriptional regulator EJA96_11020 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) EJA96_11070 ENOG4105CDV Ompa motb domain protein EJA96_11075 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) EJA96_11085 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit EJA96_11090 ENOG4108IFG nitrite reductase, (NAD(P)H) EJA96_11110 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) EJA96_11120 ENOG4107QIJ Aconitate hydratase 2 EJA96_11135 ENOG4105Q9Y Universal stress protein EJA96_11140 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase EJA96_11155 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) EJA96_11200 ENOG4108A04 Beta-lactamase EJA96_11205 ENOG4105JJR Histidine kinase EJA96_11210 ENOG4107EXC regulatoR EJA96_11225 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) EJA96_11235 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) EJA96_11240 ENOG4105K70 DNA-binding protein EJA96_11250 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EJA96_11255 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH EJA96_11260 ENOG4108JQ5 ABC transporter EJA96_11265 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component EJA96_11270 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component EJA96_11275 ENOG4105E43 Extracellular solute-binding protein, family 5 EJA96_11280 ENOG4105E43 Extracellular solute-binding protein, family 5 EJA96_11285 ENOG4105E9H Lytic Murein transglycosylase EJA96_11290 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) EJA96_11305 ENOG4107RZZ dna polymerase iii epsilon subunit EJA96_11315 ENOG4105CXN decarboxylase EJA96_11320 ENOG4105D5Q Arginine ornithine antiporter EJA96_11330 ENOG4105E39 Enoyl-CoA hydratase EJA96_11355 ENOG4108KB2 LysR family Transcriptional regulator EJA96_11360 ENOG4105CHR reductase EJA96_11365 ENOG41061TZ Short-chain dehydrogenase reductase Sdr EJA96_11385 ENOG4105ERU peptidase EJA96_11415 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) EJA96_11450 ENOG4105C3R Methionine synthase EJA96_11480 ENOG4105XDF Protein of unknown function (DUF1272) EJA96_11505 ENOG4105CJW magnesium transporter EJA96_11515 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i EJA96_11520 ENOG4105CKW Inner membrane protein yedI EJA96_11525 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) EJA96_11535 ENOG4105HEI LysR family (Transcriptional regulator EJA96_11545 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) EJA96_11550 ENOG4105E0C molybdate abc transporter EJA96_11555 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein EJA96_11560 ENOG4108IG5 Transcriptional regulator EJA96_11565 ENOG4105F2V VRR-NUC domain-containing protein EJA96_11585 ENOG4105GVR general secretion pathway protein D EJA96_11660 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain EJA96_11675 ENOG4105CQ2 DNA polymerase EJA96_11695 ENOG4108TGY Glutathione S-transferase EJA96_11710 ENOG4105CUJ penicillin amidase EJA96_11735 ENOG4105VJY transcriptional regulator EJA96_11765 ENOG4105JAB phenazine biosynthesis protein, phzf family EJA96_11795 ENOG4108VN5 Inherit from COG: PepSY-associated TM helix EJA96_11810 ENOG4108SF5 RNA Polymerase EJA96_11845 ENOG4105D5U fad dependent oxidoreductase EJA96_11860 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EJA96_11890 ENOG4105DDY UPF0142 protein ycaO EJA96_11900 ENOG4105D9U N-acetyltransferase EJA96_11910 ENOG4107SDU Methyl-accepting chemotaxis EJA96_11915 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit EJA96_11920 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding EJA96_11925 ENOG4105C7W Xanthine dehydrogenase EJA96_11970 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_11975 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator EJA96_11985 ENOG4105CNN ABC, transporter EJA96_11990 ENOG4105ETE Transcriptional regulator (LacI family EJA96_12050 ENOG4105CC0 LysR family Transcriptional regulator EJA96_12055 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) EJA96_12065 ENOG4105C5H ABC transporter EJA96_12105 ENOG4105CWM branched-chain amino acid transport system II carrier protein EJA96_12110 ENOG4105DIJ Phosphoethanolamine transferase EJA96_12140 ENOG4108W5X Transcriptional Regulator, LuxR family EJA96_12160 ENOG4105DZG Dehydrogenase EJA96_12170 ENOG4105C26 Dehydrogenase EJA96_12180 ENOG4105JIE May be involved in the transport of PQQ or its precursor to the periplasm (By similarity) EJA96_12210 ENOG4105I8F Histidine kinase EJA96_12215 ENOG4105F9N Major Facilitator Superfamily EJA96_12230 ENOG4105KQ5 peptidylprolyl cis-trans isomerase EJA96_12235 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EJA96_12240 ENOG4105DND Transcriptional regulator EJA96_12245 ENOG4105D6N CoA-transferase, subunit a EJA96_12260 ENOG4105CRW Short chain fatty acid transporter EJA96_12265 ENOG4105DTD Dehydrogenase EJA96_12270 ENOG4105CY2 Citrate transporter EJA96_12275 ENOG4108JUB Transcriptional regulator EJA96_12280 ENOG4105D2S major facilitator superfamily EJA96_12285 ENOG4108RXX maleylacetoacetate isomerase EJA96_12290 ENOG4105ERH Fumarylacetoacetate hydrolase EJA96_12305 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase EJA96_12320 ENOG4107QX3 carboxylase EJA96_12325 ENOG4105C1G acyl-Coa dehydrogenase EJA96_12330 ENOG4108Z6Z Transcriptional regulator EJA96_12335 ENOG4108ZK4 sdia-regulated domain-containing protein EJA96_12345 ENOG4105BZS acriflavin resistance protein EJA96_12355 ENOG4108IG5 Transcriptional regulator EJA96_12365 ENOG4105C6Y Udp-glucose 6-dehydrogenase EJA96_12370 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EJA96_12375 ENOG4105HUJ glyoxalase bleomycin resistance protein dioxygenase EJA96_12380 ENOG4105DC8 reductase EJA96_12385 ENOG4105DHU Bile acid EJA96_12395 ENOG4108XM1 transcriptional regulator AsnC family EJA96_12415 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EJA96_12455 ENOG4105CFQ glutamine synthetase EJA96_12460 ENOG4105CUB amino acid EJA96_12475 ENOG4105D3G Pseudouridine synthase EJA96_12495 ENOG4105CF7 AraC family transcriptional regulator EJA96_12510 ENOG4108SF5 RNA Polymerase EJA96_12525 ENOG4107B2H carbonic anhydrase EJA96_12530 ENOG4105DND Transcriptional regulator EJA96_12540 ENOG4105EQ2 LysR family Transcriptional regulator EJA96_12550 ENOG4105D05 Receptor EJA96_12560 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component EJA96_12565 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component EJA96_12575 ENOG4105C3J Cysteine desulfurase EJA96_12605 ENOG4105D8G Major Facilitator superfamily EJA96_12625 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) EJA96_12635 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase EJA96_12670 ENOG4105C85 amino acid EJA96_12690 ENOG4105F7P transcriptional regulator AsnC family EJA96_12695 ENOG4105FUY alpha subunit EJA96_12700 ENOG4105CAQ asparagine synthetase EJA96_12705 ENOG4106DX9 Aromatic-ring-hydroxylating dioxygenase beta subunit EJA96_12710 ENOG4105EBM Alpha Beta Hydrolase Fold protein EJA96_12730 ENOG4105FBW Monooxygenase EJA96_12745 ENOG4105K6V RNA polymerase EJA96_12765 ENOG4107RN6 Monooxygenase EJA96_12795 ENOG4107R7A Allophanate hydrolase subunit 2 EJA96_12815 ENOG4107RGD Major Facilitator superfamily EJA96_12840 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EJA96_12875 ENOG4105CC0 LysR family Transcriptional regulator EJA96_12880 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) EJA96_12885 ENOG4105C26 Dehydrogenase EJA96_12890 ENOG4105GTN ParB Domain Protein Nuclease EJA96_12900 ENOG4105BZV Phosphoadenosine phosphosulfate reductase EJA96_12910 ENOG4105GQR Chaperone EJA96_12915 ENOG4105CW0 outer membrane usher protein EJA96_12925 ENOG4105GQR Chaperone EJA96_12945 ENOG4107VMU Membrane EJA96_12960 ENOG4105DQE DNA ligase EJA96_12995 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) EJA96_13010 ENOG4105CH6 catalase EJA96_13020 ENOG4105KT7 mgtC SapB transporter EJA96_13030 ENOG4105FDF Could be involved in DNA repair (By similarity) EJA96_13035 ENOG4105EP6 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity) EJA96_13040 ENOG4105CG3 alpha amylase, catalytic region EJA96_13045 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) EJA96_13050 ENOG4107UXM Membrane EJA96_13055 ENOG4105DZQ phospholipase D Transphosphatidylase EJA96_13060 ENOG4105X23 Endonuclease Exonuclease phosphatase EJA96_13105 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) EJA96_13110 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) EJA96_13145 ENOG4105CN9 Peptidase m42 family protein EJA96_13175 ENOG4105BZU Histidine kinase EJA96_13190 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EJA96_13225 ENOG41080XP Cbs domain EJA96_13230 ENOG4105CG3 alpha amylase, catalytic region EJA96_13235 ENOG41065RR hydrogen cyanide synthase HcnA EJA96_13240 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein EJA96_13245 ENOG4105MWK D-amino acid dehydrogenase, small subunit EJA96_13250 ENOG4108WUH Transcriptional regulator, TetR family EJA96_13255 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein EJA96_13265 ENOG4106KE4 Dehydrogenase EJA96_13270 ENOG4105BZU Histidine kinase EJA96_13280 ENOG4105DRP amino acid AbC transporter EJA96_13395 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) EJA96_13400 ENOG4105EPF Outer membrane porin EJA96_13405 ENOG4105CSP Major Facilitator Superfamily EJA96_13410 ENOG4105CXK mandelate racemase muconate lactonizing EJA96_13420 ENOG4105CZJ Aldehyde dehydrogenase EJA96_13425 ENOG4105F1S paraquat-inducible protein a EJA96_13430 ENOG4105DY2 Paraquat-inducible protein b EJA96_13440 ENOG4108JU7 Transcriptional regulator EJA96_13455 ENOG4105C1G acyl-Coa dehydrogenase EJA96_13470 ENOG41062QD Membrane EJA96_13475 ENOG4107QN1 sodium solute EJA96_13490 ENOG4108JPW Aminotransferase EJA96_13495 ENOG4105C26 Dehydrogenase EJA96_13500 ENOG4105CUB amino acid EJA96_13515 ENOG4105CT3 Monooxygenase EJA96_13530 ENOG4105CJP fad dependent oxidoreductase EJA96_13600 ENOG4105F5W AtP-binding protein EJA96_13605 ENOG4105D70 Integrase catalytic subunit EJA96_13635 ENOG4107R13 MMPL domain protein EJA96_13640 ENOG4107SP2 The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity EJA96_13650 ENOG4105G9B Transcriptional regulator EJA96_13885 ENOG4108RPX mosc domain containing protein EJA96_13900 ENOG4105D3Q Sugar transferase EJA96_13910 ENOG4108KBE Glycosyl transferase, family 2 EJA96_13915 ENOG4105DAY polysaccharide export protein EJA96_13950 ENOG4105CJR Integral membrane protein (MviN EJA96_13975 ENOG4105J0Q Transcriptional regulator EJA96_13980 ENOG4107R0V Pyruvate dehydrogenase EJA96_13985 ENOG4105CPP Dehydrogenase, E1 component EJA96_13990 ENOG4107QSN dihydrolipoamide acetyltransferase EJA96_13995 ENOG4107QN2 dihydrolipoyl dehydrogenase EJA96_14010 ENOG4105HDK L-asparaginase EJA96_14040 ENOG4105JQN Transcriptional regulator EJA96_14045 ENOG4108M60 Transcriptional regulator EJA96_14055 ENOG4105D7K pfkb domain protein EJA96_14065 ENOG4105C5I Dehydrogenase EJA96_14090 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) EJA96_14110 ENOG4105XYF acetyltransferase EJA96_14115 ENOG4105CJN penicillin-binding protein EJA96_14120 ENOG4108Z4X TRANSCRIPTIONal EJA96_14130 ENOG4105DQ4 alcohol dehydrogenase EJA96_14135 ENOG4105CF7 AraC family transcriptional regulator EJA96_14140 ENOG41082YX Transcriptional regulator, arsr family EJA96_14150 ENOG4107WAU Protein tyrosine phosphatase EJA96_14155 ENOG4105CAU Arsenical resistance protein, ArsH EJA96_14200 ENOG4105CHB tonB-dependent Receptor EJA96_14210 ENOG4105DZG Dehydrogenase EJA96_14240 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) EJA96_14245 ENOG4108X79 transcriptional regulator EJA96_14250 ENOG4105E03 chitinase EJA96_14285 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EJA96_14300 ENOG4105E2B Taurine dioxygenase EJA96_14310 ENOG4108JCI Transcriptional regulator EJA96_14325 ENOG4107S1E Beta-lactamase EJA96_14330 ENOG4105HEI LysR family (Transcriptional regulator EJA96_14335 ENOG4105CJP fad dependent oxidoreductase EJA96_14350 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family EJA96_14355 ENOG4105C6Z Gluconate EJA96_14365 ENOG4105C26 Dehydrogenase EJA96_14385 ENOG4105DG7 nitrate ABC transporter EJA96_14390 ENOG4105I5W Transporter EJA96_14395 ENOG4105D7T ABC transporter EJA96_14425 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component EJA96_14435 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EJA96_14440 ENOG4105DEI Mannitol dehydrogenase EJA96_14465 ENOG4107T8P acyl-Coa dehydrogenase EJA96_14475 ENOG4105D01 (LipO)protein EJA96_14485 ENOG4108UMI ABC transporter, permease EJA96_14490 ENOG4107VXM glycerophosphoryl diester phosphodiesterase EJA96_14495 ENOG4105D6Z AFG1 family ATPase EJA96_14500 ENOG4107SM7 Transcriptional regulator EJA96_14510 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) EJA96_14515 ENOG4108UZX fmn reductase EJA96_14525 ENOG4107SM7 Transcriptional regulator EJA96_14600 ENOG4105CS6 Rhs element vgr protein EJA96_14645 ENOG4105DMF Dehydrogenase EJA96_14650 ENOG4108MGI Transcriptional regulator EJA96_14655 ENOG41090R7 Ferric uptake EJA96_14660 ENOG4107SQI penicillin amidase EJA96_14665 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) EJA96_14680 ENOG4105DJY efflux transporter, rnd family, mfp subunit EJA96_14690 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EJA96_14715 ENOG4108V3E phosphoribosylglycinamide formyltransferase EJA96_14720 ENOG4105IBP Cyclic peptide transporter EJA96_14725 ENOG4105E0K tonB-dependent siderophore receptor EJA96_14735 ENOG4105CEY Amp-dependent synthetase and ligase EJA96_14790 ENOG4105FDK ABC transporter EJA96_14835 ENOG4105HEI LysR family (Transcriptional regulator EJA96_14840 ENOG4105EUB pirin domain protein EJA96_14845 ENOG4105CHJ isochorismatase hydrolase EJA96_14850 ENOG4105J5J Outer membrane porin EJA96_14920 ENOG4105CSR polyphosphate kinase 2 EJA96_14930 ENOG4105Y49 secretion protein, HlyD family EJA96_14940 ENOG4107Z11 Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity) EJA96_14950 ENOG4108NUU Transcriptional regulator EJA96_15010 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) EJA96_15020 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor EJA96_15025 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) EJA96_15030 ENOG4105EJC lysr family transcriptional regulator EJA96_15060 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) EJA96_15165 ENOG4105D5K Hemolysin activator protein EJA96_15190 ENOG4108SF5 RNA Polymerase EJA96_15210 ENOG4105D2S major facilitator superfamily EJA96_15215 ENOG4108RXX maleylacetoacetate isomerase EJA96_15230 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase EJA96_15240 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) EJA96_15245 ENOG4105XJC Two component transcriptional regulator (Winged helix family EJA96_15260 ENOG4105NQN cytochrome C EJA96_15270 ENOG4105DEN Luciferase family EJA96_15350 ENOG4107Y2X deaminase EJA96_15355 ENOG4105DJ2 Major Facilitator Superfamily EJA96_15380 ENOG4105J5J Outer membrane porin EJA96_15390 ENOG410626B catechol 1,2-dioxygenase EJA96_15395 ENOG4105NN7 muconolactone delta-isomerase EJA96_15400 ENOG4105DTQ mandelate racemase muconate lactonizing EJA96_15410 ENOG4108KB2 LysR family Transcriptional regulator EJA96_15425 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit EJA96_15430 ENOG4108YS2 small subunit EJA96_15435 ENOG4105F57 Anthranilate dioxygenase reductase EJA96_15495 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EJA96_15500 ENOG4105BZS acriflavin resistance protein EJA96_15505 ENOG4105BZS acriflavin resistance protein EJA96_15540 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) EJA96_15545 ENOG4105BZG amino acid carrier protein EJA96_15555 ENOG4105CPC Aldo Keto reductase EJA96_15560 ENOG4108HPI phosphatidate Cytidylyltransferase EJA96_15575 ENOG41077RS Phosphatase EJA96_15580 ENOG4105E8V Alpha Beta Hydrolase Fold protein EJA96_15585 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase EJA96_15595 ENOG4105CFU surface antigen EJA96_15605 ENOG4105CGK Exodeoxyribonuclease III EJA96_15610 ENOG4108UYE Lactoylglutathione lyase EJA96_15615 ENOG4105EXG Transcriptional regulator EJA96_15625 ENOG4105DU1 integral membrane protein, terc EJA96_15645 ENOG4105C1G acyl-Coa dehydrogenase EJA96_15665 ENOG4108ZX5 transcriptional regulator EJA96_15670 ENOG4105CEY Amp-dependent synthetase and ligase EJA96_15695 ENOG4108NVR Methyl-accepting chemotaxis EJA96_15705 ENOG4105CHH sulfate transporter EJA96_15745 ENOG4106W3I PA-I galactophilic lectin EJA96_15755 ENOG4105BZU Histidine kinase EJA96_15760 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_15770 ENOG4105EEF Alkane 1-monooxygenase EJA96_15790 ENOG4105VDT -acetyltransferase EJA96_15800 ENOG4105NF4 modulator of drug activity EJA96_15820 ENOG4105BZU Histidine kinase EJA96_15845 ENOG4105WH1 Two component transcriptional regulator luxr family EJA96_15855 ENOG4105CN2 monooxygenase, FAD-binding EJA96_15875 ENOG4105WH1 Two component transcriptional regulator luxr family EJA96_15880 ENOG4108HM4 ABC transporter EJA96_15890 ENOG4105GVF (ABC) transporter EJA96_15900 ENOG4105GVF (ABC) transporter EJA96_15905 ENOG4105FDT acyl-CoA dehydrogenase EJA96_15915 ENOG4105GVF (ABC) transporter EJA96_15925 ENOG4105C5Q Transcriptional regulator EJA96_15930 ENOG4108T2C cysteine dioxygenase type I EJA96_15945 ENOG4108MN8 Membrane EJA96_15950 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) EJA96_15955 ENOG4108ZKU Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) EJA96_15965 ENOG4108Z0T Part of a sulfur-relay system (By similarity) EJA96_15970 ENOG4107QYG anthranilate phosphoribosyltransferase EJA96_15975 ENOG4105CHF Glutathione S-transferase EJA96_15980 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) EJA96_15990 ENOG4105D1H recombination factor protein RarA EJA96_16000 ENOG4105CNU cell division protein FtsK EJA96_16005 ENOG4105C3M thioredoxin reductase EJA96_16020 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) EJA96_16025 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EJA96_16035 ENOG4105VEQ Cold shock protein EJA96_16045 ENOG4105E9K Isocitrate dehydrogenase EJA96_16070 ENOG4107QTF adenylosuccinate lyase EJA96_16075 ENOG4105EZE Cupin 4 family protein EJA96_16080 ENOG41082BV acetyltransferase EJA96_16100 ENOG4107RET Isocitrate lyase EJA96_16130 ENOG4105GKE subunit e EJA96_16135 ENOG4107QIZ NADH dehydrogenase EJA96_16140 ENOG4108IEH NADH dehydrogenase subunit g EJA96_16155 ENOG4107UFS subunit j EJA96_16165 ENOG4105D65 subunit l EJA96_16170 ENOG4105C8S subunit m EJA96_16175 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) EJA96_16180 ENOG4108I0C methyltransferase EJA96_16190 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_16195 ENOG4105D3Y Na H antiporter EJA96_16200 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_16215 ENOG4105XJC Two component transcriptional regulator (Winged helix family EJA96_16240 ENOG4105M0Y EJA96_16255 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EJA96_16265 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase EJA96_16310 ENOG4108VAU general secretion pathway protein G EJA96_16315 ENOG4105D7Q type ii secretion system EJA96_16320 ENOG4107QHF type ii secretion system protein e EJA96_16330 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) EJA96_16335 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein EJA96_16340 ENOG4105CC0 LysR family Transcriptional regulator EJA96_16365 ENOG4105CS6 Rhs element vgr protein EJA96_16375 ENOG410804D Sensor Signal Transduction Histidine Kinase EJA96_16395 ENOG4105KPV Transcriptional regulator EJA96_16410 ENOG4107QS8 (LipO)protein EJA96_16435 ENOG4105J5J Outer membrane porin EJA96_16460 ENOG4108ZX5 transcriptional regulator EJA96_16475 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EJA96_16485 ENOG4105C6T cysteine synthase EJA96_16495 ENOG4108HM4 ABC transporter EJA96_16510 ENOG4107YPT transcriptional regulator EJA96_16520 ENOG4108Z4U Ferredoxin EJA96_16620 ENOG4107QMH DNA methylase EJA96_16630 ENOG4105C0D helicase EJA96_16650 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) EJA96_16670 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) EJA96_16710 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EJA96_16740 ENOG4107U9T Pfam:Ribonuclease_BN EJA96_16750 ENOG4105W39 Membrane EJA96_16800 ENOG4105J5J Outer membrane porin EJA96_16835 ENOG4105EZR dyp-type peroxidase family protein EJA96_16845 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EJA96_16855 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) EJA96_16860 ENOG4105JAB phenazine biosynthesis protein, phzf family EJA96_16870 ENOG4105BZU Histidine kinase EJA96_16910 ENOG4105CJP fad dependent oxidoreductase EJA96_16915 ENOG4105S64 Formate nitrite transporter EJA96_16965 ENOG4105VMP Transcriptional regulator EJA96_16980 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_17045 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EJA96_17110 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EJA96_17125 ENOG4105I93 response regulator EJA96_17145 ENOG4106S9K Transcriptional regulator EJA96_17190 ENOG4105E3A (ABC) transporter EJA96_17195 ENOG4105DA5 (ABC) transporter EJA96_17200 ENOG4108TGY Glutathione S-transferase EJA96_17210 ENOG4107QPN acyl-Coa dehydrogenase EJA96_17295 ENOG4107MKT Stringent starvation protein a EJA96_17300 ENOG4108ZGC gaf domain protein EJA96_17305 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) EJA96_17310 ENOG4105BZU Histidine kinase EJA96_17315 ENOG4105K56 Transcriptional regulator EJA96_17330 ENOG4105CHM Aminotransferase EJA96_17355 ENOG41068KF Universal stress protein EJA96_17365 ENOG4105C0R drug resistance transporter emrb qaca subfamily EJA96_17375 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EJA96_17385 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b EJA96_17395 ENOG4105E39 Enoyl-CoA hydratase EJA96_17405 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase EJA96_17410 ENOG4105T0Z Conserved Protein EJA96_17430 ENOG4105EJC lysr family transcriptional regulator EJA96_17435 ENOG4105K56 Transcriptional regulator EJA96_17440 ENOG4108ZHJ Organic hydroperoxide resistance protein EJA96_17465 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EJA96_17475 ENOG4108UJV acyl-CoA thioesterase i EJA96_17480 ENOG4108I0Y (ABC) transporter EJA96_17485 ENOG4105CV6 ABC transporter, permease EJA96_17490 ENOG4108RRZ Transcription elongation factor GreB EJA96_17500 ENOG4107XID 2'-5' rna ligase EJA96_17505 ENOG4107IFA Lipase (EC 3.1.1.3) EJA96_17510 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) EJA96_17515 ENOG4108VGI doxx family EJA96_17520 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) EJA96_17525 ENOG4105F8V Hydrolase, tatD family EJA96_17545 ENOG4105BZU Histidine kinase EJA96_17570 ENOG4105C7R Atpase associated with various cellular activities aaa_3 EJA96_17580 ENOG4105CBN LysR family transcriptional regulator EJA96_17590 ENOG4105CWB LysR family transcriptional Regulator EJA96_17600 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_17620 ENOG4108RZE Tetr family transcriptional regulator EJA96_17635 ENOG4107QX3 carboxylase EJA96_17640 ENOG4105C1G acyl-Coa dehydrogenase EJA96_17655 ENOG4105CHR reductase EJA96_17675 ENOG4108WQI RNA Polymerase EJA96_17680 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EJA96_17690 ENOG41068CG regulatoR EJA96_17720 ENOG4105DVK Precorrin-2 c20-methyltransferase EJA96_17725 ENOG41081F0 Precorrin-8x methylmutase EJA96_17800 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_17805 ENOG4107F9Y LysR family transcriptional regulator EJA96_17810 ENOG4105CH2 amidohydrolase EJA96_17815 ENOG4105E89 ABC transporter EJA96_17820 ENOG4105DSP amino acid AbC transporter EJA96_17825 ENOG4106YG3 ABC transporter EJA96_17830 ENOG4108JEH abc transporter atp-binding protein EJA96_17855 ENOG4108MGI Transcriptional regulator EJA96_17860 ENOG4108IND Tetr family transcriptional regulator EJA96_17865 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EJA96_17870 ENOG4105F27 Major Facilitator EJA96_17895 ENOG4105C2W permease EJA96_17925 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EJA96_17930 ENOG4105CTK cobaltochelatase, cobn subunit EJA96_17935 ENOG4107QRP cobalamin biosynthesis protein CobW EJA96_17950 ENOG4108P62 biosynthesis protein (CbiG) EJA96_17955 ENOG4105CIA precorrin-4 C(11)-methyltransferase EJA96_17970 ENOG4105C10 Electron transfer flavoprotein EJA96_17975 ENOG4105BZJ Electron transfer flavoprotein EJA96_17980 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase EJA96_18005 ENOG4105C9B Cysteine desulfurase EJA96_18010 ENOG4105F8V Hydrolase, tatD family EJA96_18020 ENOG4107QRG dna polymerase iii EJA96_18030 ENOG4105HHA aminodeoxychorismate lyase EJA96_18040 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EJA96_18045 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) EJA96_18050 ENOG4105CHR reductase EJA96_18055 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EJA96_18070 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein EJA96_18075 ENOG4108UHJ MAF-like protein EJA96_18080 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) EJA96_18090 ENOG4105EI2 Pseudouridine synthase EJA96_18105 ENOG4105D4A Cell wall formation (By similarity) EJA96_18130 ENOG4109015 Biopolymer transport protein exbD tolR EJA96_18150 ENOG4105D60 lipoprotein releasing system transmembrane protein EJA96_18160 ENOG4105D60 lipoprotein releasing system transmembrane protein EJA96_18175 ENOG4108QXE glycerophosphoryl diester phosphodiesterase EJA96_18190 ENOG4105CJ2 (LipO)protein EJA96_18210 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) EJA96_18225 ENOG4105C85 amino acid EJA96_18245 ENOG4107RHB Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity) EJA96_18265 ENOG4106AIJ Cell Division EJA96_18280 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) EJA96_18290 ENOG4105CHU acetyl-coa acetyltransferase EJA96_18315 ENOG41081QV Universal stress protein EJA96_18325 ENOG4105C5H ABC transporter EJA96_18330 ENOG4107SC1 transglycosylase EJA96_18345 ENOG4107TE5 Lipid kinase EJA96_18350 ENOG4108CWB sugar kinase ygcE EJA96_18370 ENOG4105CVM Molybdenum cofactor synthesis domain protein EJA96_18375 ENOG4108RIR Molybdenum cofactor biosynthesis protein EJA96_18405 ENOG4105J7D transcriptional regulator EJA96_18420 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) EJA96_18425 ENOG4105EPF Outer membrane porin EJA96_18460 ENOG4105BZU Histidine kinase EJA96_18465 ENOG4108WQH regulatoR EJA96_18470 ENOG41090ED Protein with unknown function (DUF469) EJA96_18475 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family EJA96_18480 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) EJA96_18490 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) EJA96_18540 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) EJA96_18565 ENOG4105GSQ TM1410 hypothetical-related protein EJA96_18570 ENOG4105C7I Dehydrogenase EJA96_18580 ENOG4105C7R Atpase associated with various cellular activities aaa_3 EJA96_18615 ENOG4105ETX regulatoR EJA96_18620 ENOG4105US7 Histidine kinase EJA96_18635 ENOG4105D25 secreted protein EJA96_18650 ENOG4105CD8 aminopeptidase N EJA96_18660 ENOG4105VUT cytoplasmic protein EJA96_18695 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EJA96_18705 ENOG4108ZX5 transcriptional regulator EJA96_18725 ENOG41064QQ General secretion pathway EJA96_18735 ENOG4108RTD type II secretion system protein K EJA96_18740 ENOG4108WWZ General secretion pathway protein J EJA96_18745 ENOG4105X5Z General secretion pathway protein I EJA96_18750 ENOG4105VWV general secretion pathway protein h EJA96_18755 ENOG4108VAU general secretion pathway protein G EJA96_18760 ENOG4105D7Q type ii secretion system EJA96_18765 ENOG4107QHF type ii secretion system protein e EJA96_18770 ENOG4106I3Z EJA96_18775 ENOG4105GVR general secretion pathway protein D EJA96_18780 ENOG4107EXU Short-chain dehydrogenase reductase Sdr EJA96_18785 ENOG4105C28 cystathionine EJA96_18790 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase EJA96_18795 ENOG4105E96 Colicin v production protein EJA96_18800 ENOG41063M6 Cell Division Protein EJA96_18805 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase EJA96_18820 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) EJA96_18830 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) EJA96_18835 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) EJA96_18840 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EJA96_18845 ENOG4105F2W methyltransferase EJA96_18860 ENOG4108MP6 LysR family Transcriptional regulator EJA96_18865 ENOG4105KME endoribonuclease L-psp EJA96_18870 ENOG4105HEI LysR family (Transcriptional regulator EJA96_18890 ENOG4105CYX Short-chain dehydrogenase reductase Sdr EJA96_18895 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) EJA96_18905 ENOG4108UHU Aldolase EJA96_18910 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) EJA96_18940 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) EJA96_18945 ENOG4105HEI LysR family (Transcriptional regulator EJA96_18960 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) EJA96_18965 ENOG4105CGF Aromatic amino acid aminotransferase EJA96_18985 ENOG4105ESV Glycosyl transferase, family 4 EJA96_19000 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase EJA96_19010 ENOG4105C5E polysaccharide biosynthesis protein EJA96_19055 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) EJA96_19065 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase EJA96_19070 ENOG4105CIH Imidazole acetol-phosphate transaminase EJA96_19075 ENOG4105CQC Prephenate dehydratase EJA96_19085 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EJA96_19095 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) EJA96_19105 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EJA96_19110 ENOG4105UBK short-chain dehydrogenase reductase EJA96_19125 ENOG4105D6U Sodium Glutamate Symporter EJA96_19130 ENOG4105BZU Histidine kinase EJA96_19145 ENOG4105FE9 pseudouridine synthase EJA96_19155 ENOG4108UHU Aldolase EJA96_19160 ENOG4108Q79 6-phosphogluconolactonase (EC 3.1.1.31) EJA96_19165 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase EJA96_19170 ENOG4106KNT transcriptional regulator EJA96_19175 ENOG4105DSB aldose 1-epimerase EJA96_19185 ENOG4105TW1 Carbohydrate-selective porin OprB EJA96_19190 ENOG4108IJ9 (ABC) transporter EJA96_19200 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component EJA96_19215 ENOG4105E0F Histidine kinase EJA96_19220 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EJA96_19230 ENOG4105C01 Dihydroxy-acid dehydratase EJA96_19235 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase EJA96_19250 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) EJA96_19255 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) EJA96_19260 ENOG4107RTD sua5 ycio yrdc ywlc family protein EJA96_19265 ENOG4105DB7 PHP domain protein EJA96_19275 ENOG4105K9H YciI-like protein EJA96_19285 ENOG4105E3W Two component transcriptional regulator (Winged helix family EJA96_19295 ENOG410804D Sensor Signal Transduction Histidine Kinase EJA96_19305 ENOG41069NU Nitroreductase EJA96_19310 ENOG4105PI0 Ferredoxin EJA96_19315 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) EJA96_19325 ENOG4105DHJ ABC, transporter EJA96_19340 ENOG4108ZX5 transcriptional regulator EJA96_19350 ENOG4105F8J Adenylate Guanylate cyclase EJA96_19355 ENOG4105BZF Glycosyl transferase (Group 1 EJA96_19370 ENOG4108Z7R Chaperone CsaA EJA96_19390 ENOG4108K3A Glutathione S-transferase EJA96_19395 ENOG4107S9F NmrA family EJA96_19400 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) EJA96_19410 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) EJA96_19425 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) EJA96_19430 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) EJA96_19435 ENOG4105BZ1 (ABC) transporter EJA96_19465 ENOG4107QN1 sodium solute EJA96_19470 ENOG41062QD Membrane EJA96_19490 ENOG410903C (LipO)protein EJA96_19495 ENOG4105EUB pirin domain protein EJA96_19505 ENOG4105D1S lipid A biosynthesis EJA96_19515 ENOG4107QMS site-determining protein EJA96_19525 ENOG4105D3G Pseudouridine synthase EJA96_19535 ENOG4105D9U N-acetyltransferase EJA96_19555 ENOG4105F38 ABC transporter, permease EJA96_19570 ENOG4105EAC phosphoserine phosphatase EJA96_19575 ENOG4108JA1 polyketide synthase EJA96_19580 ENOG4105CN1 protease EJA96_19585 ENOG4105BZU Histidine kinase EJA96_19615 ENOG4108V1T peptidylprolyl cis-trans isomerase EJA96_19635 ENOG4105C09 Bile acid EJA96_19640 ENOG4105KPY Small multidrug resistance protein EJA96_19645 ENOG4105VEQ Cold shock protein EJA96_19655 ENOG4105GAV receptor EJA96_19670 ENOG4105BZU Histidine kinase EJA96_19710 ENOG4108SDF phosphate-selective porin O and P EJA96_19760 ENOG4105JXB ankyrin repeat-containing protein EJA96_19805 ENOG4105K59 histidine triad (HIT) protein EJA96_19815 ENOG4105CQ7 ATP-dependent helicase EJA96_19830 ENOG4105CEY Amp-dependent synthetase and ligase EJA96_19835 ENOG4105CEY Amp-dependent synthetase and ligase EJA96_19840 ENOG4105E8V Alpha Beta Hydrolase Fold protein EJA96_19845 ENOG4108Z7G MaoC domain protein dehydratase EJA96_19850 ENOG4108SUT Major Facilitator Superfamily EJA96_19880 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) EJA96_19890 ENOG4107YZX Universal stress protein EJA96_19895 ENOG4105DIJ Phosphoethanolamine transferase EJA96_19900 ENOG4105BZU Histidine kinase EJA96_19905 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EJA96_19910 ENOG4107T9Q phosphonate abc transporter EJA96_19940 ENOG4105HSS phospholipase C EJA96_19980 ENOG4108S10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) EJA96_20000 ENOG4108RZ4 Short-chain dehydrogenase reductase Sdr EJA96_20005 ENOG4106A3M Cytochrome p-450 EJA96_20010 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein EJA96_20045 ENOG4105D78 K07001 NTE family protein EJA96_20075 ENOG4105C9U ATP-dependent DNA helicase RecQ EJA96_20085 ENOG4108KXV response regulator EJA96_20095 ENOG4105BZU Histidine kinase EJA96_20100 ENOG4107R88 Chemotaxis protein (CheV) EJA96_20120 ENOG4106825 Type iv pilus assembly EJA96_20145 ENOG4105FDR Membrane EJA96_20170 ENOG4108S3N antar domain-containing protein EJA96_20175 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein EJA96_20180 ENOG4106H31 ATP-dependent protease ATP-binding subunit-like protein EJA96_20190 ENOG4105UPP uncharacterized protein ydcA EJA96_20220 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein EJA96_20230 ENOG4105FD8 phosphonate metabolism protein PhnM EJA96_20235 ENOG4105HRV phosphonate c-p lyase system protein phnl EJA96_20240 ENOG4105ENV phosphonate C-P lyase system protein PhnK EJA96_20245 ENOG4105FT8 Phosphonate metabolism EJA96_20250 ENOG4105EKV Phosphonate metabolism protein EJA96_20265 ENOG4107RJJ Transcriptional regulator EJA96_20275 ENOG4105EHI Phosphonate ABC transporter, periplasmic EJA96_20295 ENOG4105CHR reductase EJA96_20300 ENOG4108R96 Methyltransferase, YaeB family EJA96_20315 ENOG4105HEE Binding Domain protein EJA96_20325 ENOG4105DH4 Periplasmic copper-binding protein EJA96_20330 ENOG4105CIG ABC transporter EJA96_20335 ENOG4108T0W nitrous oxide maturation protein NosY EJA96_20345 ENOG4105DP0 ferredoxin-NADP reductase EJA96_20350 ENOG4105DUM transcriptional regulator, lysR family EJA96_20385 ENOG4105DFG type I secretion outer membrane protein EJA96_20390 ENOG4107QZV Type I secretion membrane fusion protein EJA96_20405 ENOG4105X58 receptor EJA96_20450 ENOG4105CPP Dehydrogenase, E1 component EJA96_20455 ENOG4107RUY (E1 component), alpha subunit EJA96_20465 ENOG41063JG Transcriptional regulator EJA96_20475 ENOG4105D25 secreted protein EJA96_20490 ENOG4105IQJ Involved in biosynthesis of the thiamine precursor thiazole (By similarity) EJA96_20500 ENOG4105E39 Enoyl-CoA hydratase EJA96_20505 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr EJA96_20520 ENOG4105MP9 class II Aldolase EJA96_20525 ENOG41067MG lrgb family EJA96_20535 ENOG4108KB2 LysR family Transcriptional regulator EJA96_20540 ENOG4105QDK Flavodoxin EJA96_20550 ENOG410642E Short chain dehydrogenase EJA96_20555 ENOG4105EUJ GTP cyclohydrolase i EJA96_20560 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase EJA96_20575 ENOG4105F4R Transcriptional regulator mode EJA96_20580 ENOG4105E2Y ABC, transporter EJA96_20590 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) EJA96_20595 ENOG4105GVF (ABC) transporter EJA96_20610 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EJA96_20615 ENOG4105GVF (ABC) transporter EJA96_20620 ENOG4105D3R alkyl hydroperoxide reductase EJA96_20630 ENOG4105DWT malate dehydrogenase (quinone) EJA96_20640 ENOG4105CHU acetyl-coa acetyltransferase EJA96_20645 ENOG4105CSR polyphosphate kinase 2 EJA96_20670 ENOG4105CAQ asparagine synthetase EJA96_20675 ENOG4107RRY Cyanophycin synthetase EJA96_20680 ENOG4105DER m42 family EJA96_20685 ENOG4105BZU Histidine kinase EJA96_20710 ENOG41079KZ Major Facilitator Superfamily EJA96_20715 ENOG4105CUY Mechanosensitive ion channel EJA96_20720 ENOG4105NAE bifunctional deaminase-reductase domain protein EJA96_20740 ENOG4105K4H Nlp p60 protein EJA96_20750 ENOG4105EMK carboxylate amino acid amine transporter EJA96_20755 ENOG4105F87 Dehydratase EJA96_20760 ENOG4108MVS synthase EJA96_20765 ENOG4105VJY transcriptional regulator EJA96_20860 ENOG4105CSM endonuclease III EJA96_20870 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) EJA96_20875 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase EJA96_20880 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase EJA96_20915 ENOG4105C1P efflux transporter, rnd family, mfp subunit EJA96_20945 ENOG4105D3R alkyl hydroperoxide reductase EJA96_20950 ENOG4105W53 bacterioferritin-associated ferredoxin EJA96_20955 ENOG4108UQY Iron-storage protein EJA96_20960 ENOG4106UW1 Major Facilitator superfamily EJA96_20965 ENOG4105M2J Glutaredoxin EJA96_20970 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) EJA96_20985 ENOG4105DBV ornithine carbamoyltransferase EJA96_20990 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EJA96_21000 ENOG4105C6Y Udp-glucose 6-dehydrogenase EJA96_21005 ENOG4105KZJ alginate biosynthesis protein Alg8 EJA96_21010 ENOG4108UIA Alginate biosynthesis protein Alg44 EJA96_21015 ENOG4105XJP alginate biosynthesis protein EJA96_21020 ENOG4105Y9T outer membrane protein AlgE EJA96_21050 ENOG4108XTA Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate EJA96_21055 ENOG4105ZJ4 Together with AlgI and AlgJ, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate is important for the architecture of biofilms and increases EJA96_21060 ENOG4105CJT Mannose-1-phosphate guanylyltransferase EJA96_21100 ENOG4105C6Y Udp-glucose 6-dehydrogenase EJA96_21105 ENOG4105DM4 PTS System EJA96_21110 ENOG4105DE4 1-phosphofructokinase EJA96_21120 ENOG4107B7Y DNA-binding transcriptional regulator FruR EJA96_21125 ENOG4105EYA deoxyribonuclease EJA96_21135 ENOG4105CBN LysR family transcriptional regulator EJA96_21150 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EJA96_21155 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EJA96_21160 ENOG4105C26 Dehydrogenase EJA96_21165 ENOG41063TF transcriptional regulator (AraC EJA96_21175 ENOG4105C2C drug resistance transporter, Bcr CflA EJA96_21215 ENOG4105JAB phenazine biosynthesis protein, phzf family EJA96_21220 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) EJA96_21225 ENOG4108Z66 YbaK ebsC protein EJA96_21230 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) EJA96_21235 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) EJA96_21245 ENOG4105E98 transcriptional regulator DeoR family EJA96_21250 ENOG4105C6V Glycerol-3-phosphate dehydrogenase EJA96_21255 ENOG4105RA2 Membrane EJA96_21265 ENOG4105DZ2 Transcriptional regulator EJA96_21270 ENOG41090KI Outer membrane porin EJA96_21285 ENOG4105E39 Enoyl-CoA hydratase EJA96_21290 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F EJA96_21295 ENOG4105CSU acyl-Coa dehydrogenase EJA96_21300 ENOG4107RSM transcriptional regulator EJA96_21310 ENOG4105CSH Transporter EJA96_21315 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EJA96_21320 ENOG4105CUB amino acid EJA96_21345 ENOG4105CBC glutamate synthase EJA96_21350 ENOG41080IJ Diacylglycerol kinase EJA96_21365 ENOG4106IUH DTW domain containing protein EJA96_21370 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EJA96_21375 ENOG4105F38 ABC transporter, permease EJA96_21380 ENOG4105D38 putrescine abc transporter EJA96_21395 ENOG4105VRT cytoplasmic protein EJA96_21400 ENOG4107QRI Phosphoketolase EJA96_21405 ENOG4105CY0 Metallo-Beta-Lactamase EJA96_21415 ENOG4105Y3E Modulates RecA activity (By similarity) EJA96_21425 ENOG4107TH8 cina domain protein EJA96_21440 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) EJA96_21445 ENOG4108Z4U Ferredoxin EJA96_21450 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EJA96_21455 ENOG4108K5P (LipO)protein EJA96_21480 ENOG4105C4W S-formylglutathione hydrolase EJA96_21490 ENOG4105CC0 LysR family Transcriptional regulator EJA96_21495 ENOG41066VF YeeE YedE family protein EJA96_21510 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) EJA96_21530 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) EJA96_21540 ENOG4105C0B DNA polymerase III (alpha subunit) EJA96_21545 ENOG4105BZG amino acid carrier protein EJA96_21575 ENOG4105X4K outer membrane chaperone skp EJA96_21585 ENOG4105DZP Membrane-associated zinc metalloprotease EJA96_21595 ENOG4105KNE Phosphatidate cytidylyltransferase EJA96_21600 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) EJA96_21625 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EJA96_21635 ENOG4107QSS Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity) EJA96_21640 ENOG4105EEQ Na H antiporter EJA96_21660 ENOG4105KUZ arsenate reductase EJA96_21665 ENOG410829K Lysine exporter protein (Lyse ygga) EJA96_21670 ENOG4105EJ3 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity) EJA96_21675 ENOG4105C9B Cysteine desulfurase EJA96_21680 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) EJA96_21750 ENOG4105CR4 methylisocitrate lyase EJA96_21755 ENOG41081XQ Conserved Protein EJA96_21765 ENOG41072GX Peptidase M22 Glycoprotease EJA96_21775 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) EJA96_21785 ENOG4105W1Y Transcriptional regulator EJA96_21800 ENOG4105KCK Peptidoglycan-associated lipoprotein EJA96_21805 ENOG4108UVJ appr-1-p processing domain protein EJA96_21815 ENOG4105EUK rtx toxin RtxA EJA96_21855 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) EJA96_21870 ENOG4108KTQ Methyltransferase EJA96_21885 ENOG4105CSH Transporter EJA96_21895 ENOG4108KSA LysR family transcriptional regulator EJA96_22015 ENOG4108QUU Morphogenesis Protein EJA96_22025 ENOG4105CF2 Mu-like prophage FluMu protein GP28 EJA96_22055 ENOG4107SC1 transglycosylase EJA96_22180 ENOG41068CG regulatoR EJA96_22225 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EJA96_22235 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) EJA96_22240 ENOG4108VWS Yaeq family EJA96_22250 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) EJA96_22275 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F EJA96_22290 ENOG4105D98 threonine synthase EJA96_22295 ENOG4105D6E homoserine dehydrogenase EJA96_22300 ENOG4105T95 Thiol disulfide interChange protein EJA96_22305 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EJA96_22345 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY EJA96_22355 ENOG4108JU6 CBS domain protein EJA96_22365 ENOG4105CSH Transporter EJA96_22385 ENOG4108Z0R Transferase EJA96_22390 ENOG4105P8F nudix hydrolase EJA96_22395 ENOG4105E09 nadh pyrophosphatase EJA96_22405 ENOG4105FDP GntR family transcriptional regulator EJA96_22410 ENOG4105CE4 GlcNAc 6-P deacetylase EJA96_22415 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) EJA96_22425 ENOG4105CI1 PTS System EJA96_22440 ENOG4108ETH Formylglycinamide ribotide synthetase EJA96_22445 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) EJA96_22465 ENOG4108Z6B deaminase EJA96_22470 ENOG4107R16 Multicopper oxidase EJA96_22480 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EJA96_22500 ENOG4105DGU Histone deacetylase EJA96_22515 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) EJA96_22520 ENOG4108M0I Transcriptional regulator EJA96_22525 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit EJA96_22535 ENOG4105CG6 trap dicarboxylate transporter dctm subunit EJA96_22545 ENOG4105ECQ AraC Family Transcriptional Regulator EJA96_22550 ENOG4108RWI nicotinamidase EJA96_22560 ENOG41080T7 secreted protein EJA96_22570 ENOG4105DR5 peptidase EJA96_22585 ENOG4107RNH Outer membrane receptor FepA EJA96_22595 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) EJA96_22610 ENOG4105CPC Aldo Keto reductase EJA96_22625 ENOG4105CHM Aminotransferase EJA96_22635 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EJA96_22675 ENOG4105WVQ Fe-S assembly protein IscX EJA96_22680 ENOG4108ZIT Ferredoxin, 2FE-2S EJA96_22695 ENOG4108Z4V iron-sulfur cluster assembly EJA96_22700 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins EJA96_22710 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family EJA96_22715 ENOG4105D7W serine acetyltransferase EJA96_22725 ENOG4105ECY inositol monophosphatase EJA96_22730 ENOG4107MBR 17 kDa surface antigen EJA96_22735 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EJA96_22740 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EJA96_22745 ENOG4105VIE preprotein translocase, subunit YajC EJA96_22765 ENOG4105BZU Histidine kinase EJA96_22775 ENOG4108K5H permease YjgP YjgQ family protein EJA96_22780 ENOG4108M8S permease YjgP YjgQ family protein EJA96_22790 ENOG4108ZX5 transcriptional regulator EJA96_22800 ENOG4105MYG DNA polymerase iii, chi subunit EJA96_22810 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) EJA96_22825 ENOG4105C7J ABC transporter, permease EJA96_22830 ENOG4105D5T phosphonate abc transporter EJA96_22835 ENOG4107QWE )-transporter EJA96_22860 ENOG4105WAB arsR family transcriptional regulator EJA96_22875 ENOG4105ETT transcriptional Regulator, LysR family EJA96_22935 ENOG4105VE1 Phosphatidylcholine synthase EJA96_22950 ENOG4105CEY Amp-dependent synthetase and ligase EJA96_22975 ENOG4108SGR YheO domain-containing protein EJA96_22980 ENOG4105E89 ABC transporter EJA96_22995 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EJA96_23000 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EJA96_23005 ENOG4105D0D Nitrate reductase 2, gamma subunit EJA96_23010 ENOG4105R3A Nitrate reductase EJA96_23015 ENOG4108IUE nitrate reductase beta subunit EJA96_23020 ENOG4105CRU nitrate reductase, alpha subunit EJA96_23025 ENOG4105DQQ Major facilitator superfamily MFS_1 EJA96_23035 ENOG4105BZU Histidine kinase EJA96_23040 ENOG4105WH1 Two component transcriptional regulator luxr family EJA96_23060 ENOG4105E1F short-chain dehydrogenase reductase EJA96_23085 ENOG4105EEQ Na H antiporter EJA96_23095 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component EJA96_23100 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system EJA96_23105 ENOG4105E90 ABC transporter EJA96_23110 ENOG4108IJ8 ABC transporter EJA96_23115 ENOG4105Y49 secretion protein, HlyD family EJA96_23135 ENOG4105CC0 LysR family Transcriptional regulator EJA96_23140 ENOG4105C5I Dehydrogenase EJA96_23145 ENOG4108Q5Y Membrane EJA96_23150 ENOG4105ECQ AraC Family Transcriptional Regulator EJA96_23155 ENOG4108SF5 RNA Polymerase EJA96_23160 ENOG4108S3W Anti-feci sigma factor, fecr EJA96_23165 ENOG4105GAV receptor EJA96_23170 ENOG4108ZGU inhibitor of vertebrate lysozyme EJA96_23215 ENOG4105XPQ lipid carrier protein EJA96_23220 ENOG4106RZ4 Peptidase U32 EJA96_23225 ENOG4105CFP Peptidase U32 EJA96_23235 ENOG4108RIR Molybdenum cofactor biosynthesis protein EJA96_23240 ENOG4108ZAF Molybdopterin EJA96_23245 ENOG4105M00 molybdopterin converting factor, subunit 1 EJA96_23270 ENOG4108IAB Phoh family EJA96_23290 ENOG4105D25 secreted protein EJA96_23305 ENOG4105CEY Amp-dependent synthetase and ligase EJA96_23310 ENOG4105CHU acetyl-coa acetyltransferase EJA96_23320 ENOG4105R1U AraC Family Transcriptional Regulator EJA96_23330 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EJA96_23335 ENOG4105C4M (Ubiquinol oxidase) subunit I EJA96_23340 ENOG4105D01 (LipO)protein EJA96_23345 ENOG4108JU7 Transcriptional regulator EJA96_23350 ENOG4105C94 Transporter EJA96_23355 ENOG4105EPD Oligopeptide transporter, Opt family EJA96_23360 ENOG4105E2B Taurine dioxygenase EJA96_23365 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component EJA96_23370 ENOG4108IY8 ABC, transporter EJA96_23375 ENOG4106FTQ Taurine ABC transporter, periplasmic EJA96_23395 ENOG4105C29 acyl-CoA thioesterase EJA96_23405 ENOG4108YYQ gCN5-related N-acetyltransferase EJA96_23410 ENOG4108YYQ gCN5-related N-acetyltransferase EJA96_23415 ENOG4105BZU Histidine kinase EJA96_23420 ENOG4105BZU Histidine kinase EJA96_23425 ENOG4108WQH regulatoR EJA96_23435 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EJA96_23440 ENOG4105C1J atp-dependent rna helicase EJA96_23450 ENOG4105G4C Periplasmic ligand-binding sensor protein EJA96_23460 ENOG4105FBW Monooxygenase EJA96_23515 ENOG4105EW9 transcriptional regulator AsnC family EJA96_23530 ENOG4108R99 pseudouridine synthase EJA96_23545 ENOG4105FYV Amp nucleosidase EJA96_23555 ENOG4105CSU acyl-Coa dehydrogenase EJA96_23565 ENOG4105BZU Histidine kinase EJA96_23570 ENOG4105DWF phosphomethylpyrimidine kinase EJA96_23600 ENOG4105C9A Phoh family EJA96_23610 ENOG4108JU5 Magnesium and cobalt efflux protein EJA96_23620 ENOG41080C8 DUF218 domain EJA96_23665 ENOG4105EXG Transcriptional regulator EJA96_23685 ENOG4105DZ1 carboxypeptidase EJA96_23695 ENOG4105CVE Lytic murein transglycosylase EJA96_23700 ENOG4105CNI cell division protein FtsW EJA96_23705 ENOG4105CJN penicillin-binding protein EJA96_23725 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) EJA96_23745 ENOG4108KF1 Membrane EJA96_23755 ENOG41067MG lrgb family EJA96_23775 ENOG4105K4T epimerase EJA96_23785 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase EJA96_23790 ENOG4105DFU Cell wall formation (By similarity) EJA96_23800 ENOG4105C26 Dehydrogenase EJA96_23805 ENOG4105CUB amino acid EJA96_23810 ENOG4105CPD ethanolamine ammonia-lyase EJA96_23820 ENOG4105KD7 acetyltransferase EJA96_23835 ENOG4105DQR SNARE associated Golgi EJA96_23840 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) EJA96_23845 ENOG4105F0N pyrophosphate phospho-hydrolase EJA96_23850 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EJA96_23860 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) EJA96_23870 ENOG4105BZU Histidine kinase EJA96_23875 ENOG4105CJ1 ABC, transporter EJA96_23895 ENOG4105CMJ mandelate racemase muconate lactonizing EJA96_23905 ENOG4105CTB Polyprenyl synthetase EJA96_23915 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) EJA96_23930 ENOG4108WIW Aspartyl protease EJA96_23940 ENOG4108ZAI phosphatidylglycerophosphatase a EJA96_23950 ENOG4107YIM Involved in the transcription termination process (By similarity) EJA96_23960 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) EJA96_23970 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) EJA96_23990 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) EJA96_23995 ENOG4107QR8 Thioredoxin EJA96_24010 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) EJA96_24025 ENOG4105EIF outer membrane protein W EJA96_24030 ENOG4108YY7 Invasion gene expression up-regulator SirB EJA96_24035 ENOG4105C1B dTDP-glucose 4-6-dehydratase EJA96_24045 ENOG4105E7U AraC family transcriptional regulator EJA96_24055 ENOG4105CUB amino acid EJA96_24090 ENOG4108RU0 short-chain dehydrogenase reductase EJA96_24095 ENOG41068CG regulatoR EJA96_24115 ENOG4105CW0 outer membrane usher protein EJA96_24120 ENOG4105GQR Chaperone EJA96_24135 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase EJA96_24140 ENOG4105CHR reductase EJA96_24150 ENOG4105EFA 4-hydroxyphenylacetate EJA96_24155 ENOG4107UWN reductase EJA96_24175 ENOG4108I5G Major Facilitator superfamily EJA96_24185 ENOG4105CHR reductase EJA96_24200 ENOG4105CHR reductase EJA96_24205 ENOG4105EGI Transcriptional regulator EJA96_24210 ENOG4105CPI Metal Dependent Phosphohydrolase EJA96_24220 ENOG4105ETT transcriptional Regulator, LysR family EJA96_24225 ENOG41066YJ Beta-lactamase EJA96_24250 ENOG4105EWT decarboxylase family EJA96_24260 ENOG4105BZU Histidine kinase EJA96_24290 ENOG4105C26 Dehydrogenase EJA96_24295 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase EJA96_24305 ENOG4105CSP Major Facilitator Superfamily EJA96_24315 ENOG4105CNV Aldolase EJA96_24325 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) EJA96_24335 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EJA96_24340 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i EJA96_24350 ENOG4108V8F Transcriptional regulator, MarR family EJA96_24355 ENOG4105C2C drug resistance transporter, Bcr CflA EJA96_24360 ENOG4105EPF Outer membrane porin EJA96_24390 ENOG4105C42 Type I secretion membrane fusion protein (HlyD EJA96_24395 ENOG4108JJA ABC, transporter EJA96_24420 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family EJA96_24425 ENOG4105CHR reductase EJA96_24435 ENOG4107R0V Pyruvate dehydrogenase EJA96_24445 ENOG4108EMS branched-chain alpha-keto acid dehydrogenase subunit E2 EJA96_24455 ENOG4106MWK domain protein EJA96_24460 ENOG4105CPU Monooxygenase EJA96_24465 ENOG4107RBR Receptor EJA96_24475 ENOG4105E0A ABC, transporter EJA96_24480 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein EJA96_24500 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) EJA96_24525 ENOG4105CV8 reductase EJA96_24530 ENOG4105CNM Receptor EJA96_24535 ENOG41062ES Transcriptional regulator EJA96_24540 ENOG4105CAY ferredoxin--nadp reductase EJA96_24545 ENOG4108Z0Z intracellular protease Pfpi family EJA96_24555 ENOG4108UQ8 endoribonuclease L-psp EJA96_24570 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EJA96_24585 ENOG41090KI Outer membrane porin EJA96_24590 ENOG4105C7K acetolactate synthase EJA96_24630 ENOG4105C54 Major Facilitator superfamily EJA96_24635 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EJA96_24650 ENOG4108ZXC Two component transcriptional regulator, luxr family EJA96_24665 ENOG4105CSU acyl-Coa dehydrogenase EJA96_24670 ENOG4105C8F Beta-lactamase domain protein EJA96_24680 ENOG4107QWG 2-Nitropropane dioxygenase EJA96_24690 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) EJA96_24700 ENOG4105ENT Efflux transporter rnd family, mfp subunit EJA96_24705 ENOG4105BZS acriflavin resistance protein EJA96_24715 ENOG4107WY9 o-methyltransferase EJA96_24730 ENOG4106SDP Involved in the biosynthesis of the antibiotic, phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control EJA96_24765 ENOG41061H0 Monooxygenase EJA96_24785 ENOG4105CNM Receptor EJA96_24820 ENOG4105WPR Transcriptional regulator, ARAC family EJA96_24825 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase EJA96_24835 ENOG4105VIA Chorismate mutase EJA96_24845 ENOG4108UUM single-stranded DNA-binding protein EJA96_24850 ENOG4107RDB Major Facilitator EJA96_24855 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) EJA96_24860 ENOG4108UWD Iron-storage protein EJA96_24865 ENOG4105CH6 catalase EJA96_24885 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) EJA96_24900 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EJA96_25015 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) EJA96_25060 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) EJA96_25065 ENOG4105PM1 preprotein translocase subunit SecE EJA96_25105 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase EJA96_25140 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) EJA96_25145 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase EJA96_25155 ENOG4108ZP8 Acetolactate synthase small subunit EJA96_25160 ENOG4105C7K acetolactate synthase EJA96_25170 ENOG4105WP7 tRNA pseudouridine synthase C EJA96_25180 ENOG4105BZ4 penicillin-binding protein EJA96_25215 ENOG4105EHG Permease protein EJA96_25220 ENOG4107R4I Periplasmic binding protein EJA96_25225 ENOG4106QJH hemin transport protein EJA96_25230 ENOG4107ENK receptor EJA96_25255 ENOG4105CHM Aminotransferase EJA96_25265 ENOG4105CGZ zinc metallopeptidase EJA96_25275 ENOG4105C7N Xanthine uracil vitamin C permease EJA96_25295 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters EJA96_25300 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) EJA96_25310 ENOG4105BZU Histidine kinase EJA96_25315 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_25320 ENOG4105DJ0 Poly(A) Polymerase EJA96_25325 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EJA96_25350 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EJA96_25375 ENOG4105VDW Csbd family EJA96_25380 ENOG4105W4M Transport-associated protein EJA96_25415 ENOG4105CHV Transcription elongation factor NusA EJA96_25435 ENOG4107EJC Preprotein translocase subunit SecG EJA96_25450 ENOG4105EEI dihydropteroate synthase EJA96_25455 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) EJA96_25465 ENOG4105HBR Rna-binding protein EJA96_25475 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) EJA96_25480 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain EJA96_25485 ENOG4108NIW Leucine export protein LeuE EJA96_25490 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain EJA96_25520 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) EJA96_25525 ENOG41090R7 Ferric uptake EJA96_25530 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EJA96_25540 ENOG4108Z1B Cyclase dehydrase EJA96_25550 ENOG41073TP transcriptional regulator EJA96_25555 ENOG4105DAA L-lactate EJA96_25575 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) EJA96_25585 ENOG4105XJC Two component transcriptional regulator (Winged helix family EJA96_25590 ENOG4105DHQ Histidine kinase EJA96_25595 ENOG4108Z6Z Transcriptional regulator EJA96_25605 ENOG4108594 Permease of the drug metabolite transporter EJA96_25615 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase EJA96_25625 ENOG4105FDR Membrane EJA96_25640 ENOG4105CHR reductase EJA96_25645 ENOG4108ZX5 transcriptional regulator EJA96_25660 ENOG4106371 Methyltransferase EJA96_25690 ENOG4105PHD The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) EJA96_25695 ENOG4108MTT Glutamate-rich protein grpB EJA96_25730 ENOG410839U amino acid EJA96_25735 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EJA96_25745 ENOG4105EM7 Selenocysteine-specific translation elongation factor EJA96_25755 ENOG4105F46 Necessary for formate dehydrogenase activity (By similarity) EJA96_25760 ENOG4108MG3 formate dehydrogenase EJA96_25765 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein EJA96_25770 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) EJA96_25775 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) EJA96_25780 ENOG4107IFA Lipase (EC 3.1.1.3) EJA96_25785 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EJA96_25820 ENOG4107R73 Mate efflux family protein EJA96_25830 ENOG4105EAM Na Pi-cotransporter EJA96_25845 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic EJA96_25855 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase EJA96_25865 ENOG4107QN2 dihydrolipoyl dehydrogenase EJA96_25880 ENOG4105EMU Dehydrogenase EJA96_25885 ENOG4108UT2 hemolysin iii EJA96_25890 ENOG4108I0N Transporter, RarD family, DMT superfamily protein EJA96_25915 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) EJA96_25920 ENOG4108ZJT translation initiation factor, Sui1 EJA96_25925 ENOG4105PTV Nudix Hydrolase EJA96_25945 ENOG4108W2P Methyl-accepting chemotaxis EJA96_25955 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) EJA96_25965 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EJA96_25985 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EJA96_25990 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) EJA96_26000 ENOG4105C12 Phosphoribosylglycinamide synthetase EJA96_26005 ENOG4105BZU Histidine kinase EJA96_26010 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein EJA96_26015 ENOG41083Z3 extracellular ligand-binding receptor EJA96_26020 ENOG4105C32 Amino acid ABC transporter (Permease) EJA96_26025 ENOG4105CNN ABC, transporter EJA96_26030 ENOG4105C0Z ABC transporter EJA96_26035 ENOG4108IV0 ABC, transporter EJA96_26055 ENOG4108Z7F N-acetyltransferase EJA96_26065 ENOG4105CQM Urea amidohydrolase subunit alpha EJA96_26075 ENOG4105KSC Transcriptional regulator, TraR DksA family EJA96_26095 ENOG4105R8A Heat shock protein EJA96_26125 ENOG41066T0 asmA family EJA96_26130 ENOG4108UQY Iron-storage protein EJA96_26140 ENOG4105EQW The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) EJA96_26145 ENOG4108S1C Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) EJA96_26210 ENOG4108SF5 RNA Polymerase EJA96_26220 ENOG41090KI Outer membrane porin EJA96_26240 ENOG4108PTX LysR family Transcriptional regulator EJA96_26245 ENOG4105D2S major facilitator superfamily EJA96_26265 ENOG4105EMU Dehydrogenase EJA96_26270 ENOG4105CIF Ornithine Cyclodeaminase EJA96_26275 ENOG4108IV0 ABC, transporter EJA96_26280 ENOG4105C0Z ABC transporter EJA96_26285 ENOG4105CF8 branched-chain amino acid ABC transporter, permease EJA96_26290 ENOG4105C32 Amino acid ABC transporter (Permease) EJA96_26300 ENOG4105ETT transcriptional Regulator, LysR family EJA96_26315 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) EJA96_26325 ENOG4107RH7 Nicotinate phosphoribosyltransferase EJA96_26340 ENOG41090JD Blue (Type 1) copper domain protein EJA96_26345 ENOG4108URH decarboxylase EJA96_26350 ENOG4108K5P (LipO)protein EJA96_26355 ENOG4105D64 Mechanosensitive ion channel EJA96_26370 ENOG4105CCT upf0313 protein EJA96_26380 ENOG4105BZU Histidine kinase EJA96_26390 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EJA96_26395 ENOG4105CDU Replicative dna helicase EJA96_26420 ENOG4105C2N RNA methyltransferase TrmH family group 3 EJA96_26425 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) EJA96_26455 ENOG4105EPW hflc protein EJA96_26460 ENOG4107QJR hflk protein EJA96_26465 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EJA96_26485 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase EJA96_26490 ENOG4105K8N protein family UPF0079, ATPase EJA96_26495 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) EJA96_26500 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) EJA96_26510 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) EJA96_26520 ENOG4107RD7 Flagellar Motor Protein, MotA EJA96_26530 ENOG4105KHC sulfurtransferase EJA96_26550 ENOG4105BZU Histidine kinase EJA96_26555 ENOG4105EAC phosphoserine phosphatase EJA96_26565 ENOG4105S2T inner membrane protein YbcI EJA96_26575 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EJA96_26580 ENOG4108WIW Aspartyl protease EJA96_26590 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EJA96_26595 ENOG4105IPS esterase EJA96_26600 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EJA96_26610 ENOG41087AY ADP-Ribose pyrophosphatase EJA96_26625 ENOG4105DFG type I secretion outer membrane protein EJA96_26630 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF EJA96_26635 ENOG4105CHM Aminotransferase EJA96_26640 ENOG4105C7K acetolactate synthase EJA96_26650 ENOG4105C1G acyl-Coa dehydrogenase EJA96_26655 ENOG4105E39 Enoyl-CoA hydratase EJA96_26660 ENOG4108IQI permease EJA96_26665 ENOG4105BZU Histidine kinase EJA96_26675 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EJA96_26700 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase EJA96_26705 ENOG4106P55 Transcriptional regulator EJA96_26710 ENOG410814C multidrug resistance protein EJA96_26715 ENOG41087SS fad dependent oxidoreductase EJA96_26720 ENOG4107SET aldo keto reductase EJA96_26730 ENOG4105C1G acyl-Coa dehydrogenase EJA96_26735 ENOG4105C1G acyl-Coa dehydrogenase EJA96_26740 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) EJA96_26745 ENOG4105BZ1 (ABC) transporter EJA96_26760 ENOG4108SHN Glycosyl transferase, family 2 EJA96_26780 ENOG4107TAE Glycosyl transferase (Group 1 EJA96_26805 ENOG4107543 (lipo)polysaccharide EJA96_26810 ENOG4107RJ7 Glycosyl transferase (Group 1 EJA96_26815 ENOG4105D16 lipopolysaccharide heptosyltransferase i EJA96_26820 ENOG4105XA0 heptosyltransferase ii EJA96_26825 ENOG4105CM2 brancheD-chain amino acid aminotransferase EJA96_26830 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) EJA96_26835 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) EJA96_26845 ENOG4107QSN dihydrolipoamide acetyltransferase EJA96_26855 ENOG4105BZU Histidine kinase EJA96_26860 ENOG4107QXP Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) EJA96_26865 ENOG4105D6S protein involved in catabolism of external DNA EJA96_26870 ENOG4105CSU acyl-Coa dehydrogenase EJA96_26885 ENOG4105EGS Mechanosensitive ion channel EJA96_26895 ENOG410635A Membrane EJA96_26915 ENOG4107SKI cobyrinic Acid a,c-diamide synthase EJA96_26920 ENOG4106NZI LysR family Transcriptional regulator EJA96_26925 ENOG4105D94 Major Facilitator Superfamily EJA96_26950 ENOG4105BZ8 glutamate synthase EJA96_26955 ENOG4105CBC glutamate synthase EJA96_26975 ENOG4105E4G Type IV pilus EJA96_27000 ENOG4108JQC penicillin-binding protein 1A EJA96_27005 ENOG4105C6K Malic enzyme EJA96_27025 ENOG4105C25 Primosomal protein n' EJA96_27030 ENOG4105C75 arginyL-tRNA synthetase EJA96_27145 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_27150 ENOG41067ZM Uncharacterised protein family (UPF0158) EJA96_27155 ENOG4105CDA abc transporter atp-binding protein EJA96_27160 ENOG4105E5Q amino acid AbC transporter EJA96_27165 ENOG4106PMH Extracellular solute-binding protein family 3 EJA96_27190 ENOG4108Z4K mutator MutT protein EJA96_27195 ENOG4107RP9 extracellular solute-binding protein, family 3 EJA96_27200 ENOG4105KME endoribonuclease L-psp EJA96_27230 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) EJA96_27235 ENOG4105CS6 Rhs element vgr protein EJA96_27250 ENOG4105C84 Histidine ammonia-lyase EJA96_27255 ENOG4108IJ7 Glycine betaine EJA96_27260 ENOG4108HQS Glycine betaine EJA96_27270 ENOG4105C85 amino acid EJA96_27280 ENOG4105ETS cytosine purines uracil thiamine allantoin EJA96_27305 ENOG41090B9 response to stress EJA96_27310 ENOG4105CZE histidine utilization repressor EJA96_27315 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) EJA96_27340 ENOG4107XDR Lactoylglutathione lyase EJA96_27345 ENOG4108FHP Autotransporter beta-domain EJA96_27365 ENOG4108Z4X TRANSCRIPTIONal EJA96_27385 ENOG4105C5F glutamine synthetase EJA96_27395 ENOG4105D8X mechanosensitive ion channel EJA96_27410 ENOG4105CUX Signal transduction histidine kinase EJA96_27415 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_27430 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) EJA96_27440 ENOG4105VW4 glutaredoxin 3 EJA96_27450 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) EJA96_27465 ENOG4105CN1 protease EJA96_27470 ENOG4105PXI polysaccharide deacetylase EJA96_27495 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) EJA96_27510 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) EJA96_27530 ENOG4105D5U fad dependent oxidoreductase EJA96_27540 ENOG4105CEN a g-specific adenine glycosylase EJA96_27550 ENOG4105D9R oxidoreductase EJA96_27600 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EJA96_27640 ENOG4106PGW Short-chain dehydrogenase reductase Sdr EJA96_27650 ENOG4108JEH abc transporter atp-binding protein EJA96_27655 ENOG4105E89 ABC transporter EJA96_27675 ENOG4105K56 Transcriptional regulator EJA96_27685 ENOG4105CW7 secretion protein, HlyD family EJA96_27690 ENOG4105C0R drug resistance transporter emrb qaca subfamily EJA96_27725 ENOG4105C1B dTDP-glucose 4-6-dehydratase EJA96_27730 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase EJA96_27740 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase EJA96_27745 ENOG4105CQZ Histidine kinase EJA96_27750 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_27755 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit EJA96_27760 ENOG410835K Tripartite ATP-Independent Periplasmic transporter DctQ EJA96_27765 ENOG4105CG6 trap dicarboxylate transporter dctm subunit EJA96_27770 ENOG4105D5Q Arginine ornithine antiporter EJA96_27775 ENOG4105CEU Arginine dihydrolase EJA96_27780 ENOG4105DBV ornithine carbamoyltransferase EJA96_27785 ENOG4105C5B carbamate kinase EJA96_27790 ENOG4107RX2 synthase EJA96_27795 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase EJA96_27800 ENOG4107RK2 ADP-ribose diphosphatase NudE EJA96_27805 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 EJA96_27810 ENOG4109066 lysm domain bon superfamily protein EJA96_27820 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) EJA96_27840 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) EJA96_27855 ENOG4105C0A alcohol dehydrogenase EJA96_27860 ENOG4105CSU acyl-Coa dehydrogenase EJA96_27865 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EJA96_27905 ENOG4105VEJ Heat shock protein EJA96_27910 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) EJA96_27920 ENOG4107WMG L,D-carboxypeptidase EJA96_27925 ENOG4105E0F Histidine kinase EJA96_27930 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EJA96_27935 ENOG4105BZM domain protein EJA96_27965 ENOG4105CJ3 phosphate transporter EJA96_27970 ENOG4107IX6 phosphate transport regulator EJA96_27980 ENOG4107QHF type ii secretion system protein e EJA96_27995 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor EJA96_28000 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) EJA96_28005 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) EJA96_28010 ENOG4107QVT Binding-protein-dependent transport systems, inner membrane component EJA96_28015 ENOG4107QKW extracellular solute-binding protein family 1 EJA96_28020 ENOG4106NZI LysR family Transcriptional regulator EJA96_28035 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family EJA96_28045 ENOG4105D0A hydroxylase EJA96_28050 ENOG4107RAQ aminopeptidase EJA96_28065 ENOG4105W8B Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) EJA96_28075 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase EJA96_28085 ENOG4105CMI transporter EJA96_28090 ENOG4105CJ1 ABC, transporter EJA96_28095 ENOG4105D0S secretion protein (HlyD EJA96_28110 ENOG4105CXY transporter EJA96_28125 ENOG4105EXC Acyl-transferase EJA96_28130 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) EJA96_28135 ENOG4105K63 Thioredoxin EJA96_28140 ENOG4105C9X ppx gppa phosphatase EJA96_28150 ENOG4105D52 delta-aminolevulinic acid dehydratase EJA96_28155 ENOG4105KHU inner membrane protein YohD EJA96_28160 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain EJA96_28165 ENOG4108VUY thioesterase Superfamily protein EJA96_28170 ENOG4108UPT UPF0178 protein EJA96_28175 ENOG4107SJW iron permease, FTR1 EJA96_28180 ENOG410829K Lysine exporter protein (Lyse ygga) EJA96_28185 ENOG4105EE5 Membrane protein terC EJA96_28195 ENOG4105C5H ABC transporter EJA96_28215 ENOG4105PBF Anti-RNA polymerase sigma 70 factor EJA96_28220 ENOG41080I0 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) EJA96_28235 ENOG41076E6 Uroporphyrinogen-III Synthase EJA96_28245 ENOG4108NEV two component transcriptional regulator, LytTR family EJA96_28250 ENOG4108HRK Histidine kinase EJA96_28255 ENOG4105CH7 arginosuccinase EJA96_28275 ENOG4108WC9 type VI secretion system effector, hcp1 family EJA96_28280 ENOG4107QUT magnesium and cobalt transport protein CorA EJA96_28300 ENOG4107T0K Adenylate cyclase EJA96_28310 ENOG4105NXH GreA GreB family elongation factor EJA96_28320 ENOG4105XQ6 frataxin-like protein EJA96_28330 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) EJA96_28380 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme EJA96_28385 ENOG4105BZU Histidine kinase EJA96_28390 ENOG4108YZA Nitrogen regulatory protein pii EJA96_28395 ENOG4105W0Z cytoplasmic protein EJA96_28460 ENOG4107QTH restriction modification system DNA specificity domain EJA96_28495 ENOG4105KAK Plasmid pRiA4b ORF-3 family protein EJA96_28570 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) EJA96_28575 ENOG4105EY8 ABC transporter EJA96_28585 ENOG4105CMR udp-glucose 4-epimerase EJA96_28615 ENOG4105EKQ RNA-directed DNA polymerase EJA96_28620 ENOG4105EKQ RNA-directed DNA polymerase EJA96_28750 ENOG4107R4Q Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity) EJA96_28760 ENOG4105DZR Type I site-specific deoxyribonuclease EJA96_28770 ENOG4105W1Y Transcriptional regulator EJA96_28785 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) EJA96_28790 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) EJA96_28825 ENOG4108WC9 type VI secretion system effector, hcp1 family EJA96_28830 ENOG4105CS6 Rhs element vgr protein EJA96_28890 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) EJA96_28895 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes EJA96_28910 ENOG4105CJW magnesium transporter EJA96_28930 ENOG4105C0R drug resistance transporter emrb qaca subfamily EJA96_28935 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) EJA96_28940 ENOG4107S9B Shikimate dehydrogenase EJA96_28945 ENOG4108W9H Tetr family transcriptional regulator EJA96_28950 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase EJA96_28960 ENOG41090KI Outer membrane porin EJA96_28975 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) EJA96_28985 ENOG4105D2S major facilitator superfamily EJA96_29000 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase EJA96_29005 ENOG4105F2Z 3-oxoadipate enol-lactonase EJA96_29015 ENOG4105CSH Transporter EJA96_29020 ENOG4105CHU acetyl-coa acetyltransferase EJA96_29040 ENOG4107W7X Aldolase EJA96_29045 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EJA96_29055 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EJA96_29060 ENOG4105C85 amino acid EJA96_29080 ENOG4108K70 Transcriptional regulator EJA96_29095 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EJA96_29100 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase EJA96_29140 ENOG4105SG9 biopolymer transport protein, ExbD EJA96_29155 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EJA96_29160 ENOG4105W8H transhydrogenase (subunit alpha EJA96_29165 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EJA96_29170 ENOG4105E2B Taurine dioxygenase EJA96_29200 ENOG4105J5J Outer membrane porin EJA96_29205 ENOG4107Z6I Thiamine biosynthesis protein EJA96_29215 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EJA96_29220 ENOG4105E2Y ABC, transporter EJA96_29225 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) EJA96_29230 ENOG4105F6U Short-chain dehydrogenase reductase Sdr EJA96_29235 ENOG4105EJC lysr family transcriptional regulator EJA96_29245 ENOG4108VYJ response regulator receiver protein EJA96_29250 ENOG4105CBS Chea signal transduction histidine kinase EJA96_29255 ENOG4108V3W Chemotaxis protein, CheW EJA96_29260 ENOG4105C8Q Methyl-accepting chemotaxis EJA96_29265 ENOG4105BZU Histidine kinase EJA96_29270 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) EJA96_29275 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) EJA96_29295 ENOG4105BZU Histidine kinase EJA96_29305 ENOG4108R86 Transcriptional regulator EJA96_29310 ENOG4105C2W permease EJA96_29330 ENOG4105J5J Outer membrane porin EJA96_29345 ENOG4105CC0 LysR family Transcriptional regulator EJA96_29350 ENOG4105BZS acriflavin resistance protein EJA96_29365 ENOG4107HP6 Transcriptional regulator EJA96_29375 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha EJA96_29380 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta EJA96_29385 ENOG4105DDW LysR family Transcriptional regulator EJA96_29430 ENOG4105DRB nucleoside-specific channel-forming protein EJA96_29440 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) EJA96_29445 ENOG4105CSR polyphosphate kinase 2 EJA96_29450 ENOG4108JU3 Alkyl hydroperoxide reductase EJA96_29485 ENOG4107QUY Guanine deaminase EJA96_29490 ENOG4105EVZ LysR family transcriptional regulator EJA96_29495 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EJA96_29500 ENOG4105K8K Cupin 2, conserved barrel EJA96_29505 ENOG4105C26 Dehydrogenase EJA96_29515 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA EJA96_29540 ENOG4105CR8 Transcriptional regulator EJA96_29575 ENOG4107YPT transcriptional regulator EJA96_29580 ENOG4107YB6 acetyltransferase, (GNAT) family EJA96_29615 ENOG4107QS1 Cytochrome C Oxidase, Subunit III EJA96_29620 ENOG4105FT1 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) EJA96_29625 ENOG4105BZ9 Cytochrome C oxidase, subunit I EJA96_29645 ENOG4105CHH sulfate transporter EJA96_29650 ENOG4107B2H carbonic anhydrase EJA96_29685 ENOG4105CS6 Rhs element vgr protein EJA96_29715 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EJA96_29740 ENOG4108WC9 type VI secretion system effector, hcp1 family EJA96_29790 ENOG4108ZF3 Phosphatase EJA96_29795 ENOG4105D9P serine threonine protein kinase EJA96_29810 ENOG4105E6M Sulphatase-modifying factor protein EJA96_29845 ENOG4105PGM cation diffusion facilitator family transporter EJA96_29860 ENOG4108VSE mercuric transport protein EJA96_29875 ENOG4105D13 transposase EJA96_30045 ENOG41064MJ ATP synthase, subunit I EJA96_30050 ENOG4105FA0 parb-like partition protein EJA96_30055 ENOG4107QJE Chromosome Partitioning Protein EJA96_30110 ENOG41082EK Restriction modification system DNA (Specificity EJA96_30125 ENOG4105DFP Integrase EJA96_30155 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EJA96_30165 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EJA96_30170 ENOG4108F3G Type I restriction-modification system, R subunit EJA96_30185 ENOG4105CMM transposase EJA96_30210 ENOG4105KWI UPF0339 protein EJA96_30230 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase EJA96_30250 ENOG4108R3E Dna-3-methyladenine glycosylase i EJA96_30265 ENOG4105EX9 Membrane EJA96_30275 ENOG4105WAP TPR repeat-containing protein EJA96_30280 ENOG4105C1A potassium transporter peripheral membrane EJA96_30285 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B EJA96_30295 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) EJA96_30300 ENOG4108WZM domain protein EJA96_30315 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein EJA96_30325 ENOG4105E2X shikimate dehydrogenase EJA96_30335 ENOG41085KW ppic-type peptidyL-prolyl cis-trans isomerase EJA96_30355 ENOG4105CBG Sulfatase EJA96_30360 ENOG4105ETT transcriptional Regulator, LysR family EJA96_30375 ENOG4107ZHV Transcriptional regulator EJA96_30385 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) EJA96_30390 ENOG4108MGI Transcriptional regulator EJA96_30395 ENOG4105WKW Pfam:DUF1458 EJA96_30405 ENOG4105D5K Hemolysin activator protein EJA96_30495 ENOG4107PU6 Membrane EJA96_30500 ENOG41072JS exoenzyme T EJA96_30505 ENOG4106B0W Curli production assembly transport component CsgG EJA96_30515 ENOG4107Y60 (LipO)protein EJA96_30525 ENOG4105NGS secreted protein EJA96_30535 ENOG4105CAQ asparagine synthetase EJA96_30545 ENOG4108UMS Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity) EJA96_30555 ENOG4105CC0 LysR family Transcriptional regulator EJA96_30570 ENOG4108Z9K Osmotically inducible protein EJA96_30575 ENOG4105KBG Protein of unknown function (DUF1161) EJA96_30600 ENOG4107XGZ Hydrolase EJA96_30605 ENOG4108Z0R Transferase EJA96_30610 ENOG4105DGW oligopeptidase A EJA96_30615 ENOG4105VKU nucleicacid-binding protein EJA96_30650 ENOG4105CVR type I restriction-modification system EJA96_30770 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EJA96_30795 ENOG4108ZJI phenylacetic acid degradation protein EJA96_30810 ENOG4108ZK4 sdia-regulated domain-containing protein EJA96_30825 ENOG4105CHH sulfate transporter EJA96_30830 ENOG4105BZU Histidine kinase EJA96_30935 ENOG4105EQR Transposase IS116 IS110 IS902 EJA96_30975 ENOG4105C26 Dehydrogenase EJA96_31040 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase EJA96_31070 ENOG410804X Transcriptional regulator EJA96_31075 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) EJA96_31085 ENOG41083B3 HAD-superfamily subfamily IB hydrolase EJA96_31090 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase EJA96_31115 ENOG4105CD3 dihydroorotase EJA96_31130 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase EJA96_31140 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters EJA96_31160 ENOG4105CKI cobalamin synthesis protein EJA96_31165 ENOG410822N TonB family EJA96_31170 ENOG4105CSH Transporter EJA96_31175 ENOG4105CKD glutathione-regulated potassium-efflux system protein EJA96_31205 ENOG4105CHR reductase EJA96_31210 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase EJA96_31215 ENOG4105CFQ glutamine synthetase EJA96_31220 ENOG4105CHR reductase EJA96_31235 ENOG4105CKD glutathione-regulated potassium-efflux system protein EJA96_31245 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) EJA96_31255 ENOG4108HWY Beta-lactamase EJA96_31270 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_31275 ENOG4105CUB amino acid EJA96_31300 ENOG4105D01 (LipO)protein EJA96_31305 ENOG4108UMI ABC transporter, permease EJA96_31320 ENOG4105FAV ABC, transporter EJA96_31330 ENOG4105MYN Zinc uptake regulation protein EJA96_31335 ENOG4105NXV High-affinity zinc uptake system protein EJA96_31360 ENOG4105C2M dna polymerase I EJA96_31365 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) EJA96_31370 ENOG4105MPD Cytochrome EJA96_31375 ENOG4106RE7 Cytochrome EJA96_31390 ENOG4105BZU Histidine kinase EJA96_31395 ENOG41076UM multiple antibiotic resistance (MarC)-related protein EJA96_31400 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase EJA96_31405 ENOG4105ES5 Histidine kinase EJA96_31410 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EJA96_31420 ENOG4108ZGU inhibitor of vertebrate lysozyme EJA96_31430 ENOG4105CK2 sodium dicarboxylate symporter EJA96_31455 ENOG41090JX gCN5-related N-acetyltransferase EJA96_31465 ENOG4105EAM Na Pi-cotransporter EJA96_31485 ENOG4108S2Y peptide Chain Release factor EJA96_31490 ENOG4105EE5 Membrane protein terC EJA96_31495 ENOG4105D4T Citrate transporter EJA96_31505 ENOG4105RK9 auxin efflux carrier EJA96_31545 ENOG4105EXC Acyl-transferase EJA96_31550 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) EJA96_31570 ENOG4108DMA Nad-dependent epimerase dehydratase EJA96_31575 ENOG4105C0K Gdp-mannose 4,6-dehydratase EJA96_31590 ENOG4105EY8 ABC transporter EJA96_31600 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) EJA96_31615 ENOG4105CYC Transferase EJA96_31630 ENOG4105BZU Histidine kinase EJA96_31645 ENOG4105CFP Peptidase U32 EJA96_31650 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase EJA96_31655 ENOG4106KNT transcriptional regulator EJA96_31665 ENOG4105DUM transcriptional regulator, lysR family EJA96_31670 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EJA96_31675 ENOG4107QSA Oxaloacetate decarboxylase EJA96_31700 ENOG41066VF YeeE YedE family protein EJA96_31710 ENOG4108IJ0 Aspartate ammonia-lyase EJA96_31715 ENOG4107YNJ LysR family Transcriptional regulator EJA96_31730 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) EJA96_31735 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit EJA96_31750 ENOG4105DSB aldose 1-epimerase EJA96_31755 ENOG4105E2A Dehydrogenase EJA96_31785 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) EJA96_31795 ENOG4105C5W Aldolase EJA96_31805 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EJA96_31810 ENOG4105DVW rieske (2Fe-2S) EJA96_31845 ENOG4105VMP Transcriptional regulator EJA96_31860 ENOG4105C10 Electron transfer flavoprotein EJA96_31865 ENOG4105DF6 Fe-S oxidoreductase EJA96_31880 ENOG4108IGT Dipeptidase EJA96_31895 ENOG4105H3G oxidoreductase EJA96_31900 ENOG4105KME endoribonuclease L-psp EJA96_31910 ENOG4105CWC Acetylornithine deacetylase EJA96_31915 ENOG4105ECQ AraC Family Transcriptional Regulator EJA96_31925 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme EJA96_31930 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) EJA96_31945 ENOG4105HMI Membrane EJA96_31960 ENOG4105ECQ AraC Family Transcriptional Regulator EJA96_31965 ENOG4105EJQ L-serine dehydratase EJA96_31975 ENOG4108HQS Glycine betaine EJA96_31980 ENOG4108IJ7 Glycine betaine EJA96_31985 ENOG4105C94 Transporter EJA96_32010 ENOG4105NAU thioesterase Superfamily protein EJA96_32015 ENOG4105CSH Transporter EJA96_32050 ENOG4105C8U phosphate abc transporter EJA96_32055 ENOG4105C8U phosphate abc transporter EJA96_32060 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) EJA96_32065 ENOG4108UTW Plays a role in the regulation of phosphate uptake EJA96_32070 ENOG4108VYJ response regulator receiver protein EJA96_32075 ENOG4105DR5 peptidase EJA96_32080 ENOG4105C37 (CBS) domain EJA96_32085 ENOG4105BZU Histidine kinase EJA96_32090 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EJA96_32110 ENOG4108KWP DNA-binding transcriptional regulator GlcC EJA96_32115 ENOG4105CQB FAD linked oxidase domain protein EJA96_32120 ENOG4105EU8 FAD linked oxidase domain protein EJA96_32125 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) EJA96_32140 ENOG4105VCQ rubredoxin EJA96_32145 ENOG4107QZF nitrite reductase NADPH large subunit EJA96_32155 ENOG4105NYX DNA-binding protein EJA96_32170 ENOG4105CB5 ATP-dependent DNA helicase recG EJA96_32175 ENOG4105C5Q Transcriptional regulator EJA96_32200 ENOG4105KME endoribonuclease L-psp EJA96_32205 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EJA96_32215 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) EJA96_32220 ENOG4105DSJ YicC domain protein EJA96_32235 ENOG4105CGK Exodeoxyribonuclease III EJA96_32255 ENOG4105MPD Cytochrome EJA96_32295 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase EJA96_32310 ENOG4105DEF Extracellular solute-binding protein, family 5 EJA96_32320 ENOG4105W0E 50S ribosomal protein L33 EJA96_32330 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EJA96_32335 ENOG4105C26 Dehydrogenase EJA96_32340 ENOG4105C0R drug resistance transporter emrb qaca subfamily EJA96_32345 ENOG4107RZC phospholipase d EJA96_32350 ENOG4105CJP fad dependent oxidoreductase EJA96_32355 ENOG4105EW9 transcriptional regulator AsnC family EJA96_32365 ENOG410689M (LipO)protein EJA96_32375 ENOG4105MWK D-amino acid dehydrogenase, small subunit EJA96_32380 ENOG4105M4H endoribonuclease L-psp EJA96_32385 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EJA96_32390 ENOG4107VRI Transcriptional regulator EJA96_32395 ENOG4105MPD Cytochrome EJA96_32400 ENOG4105CYC Transferase EJA96_32410 ENOG4105C7K acetolactate synthase EJA96_32415 ENOG4105C4R Atp-dependent dna helicase EJA96_32420 ENOG4105BZU Histidine kinase EJA96_32425 ENOG4107QI1 Mate efflux family protein EJA96_32430 ENOG4105ETT transcriptional Regulator, LysR family EJA96_32440 ENOG4105C94 Transporter