locus-tag	class	description
PA257_0006	COG2963	transposase activity
PA257_0007	COG2801	Transposase and inactivated derivatives
PA257_0017	COG2010	Cytochrome c
PA257_0020	COG2818	Glycosylase
PA257_0023	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PA257_0025	COG0569	domain protein
PA257_0029	COG1652	LysM domain
PA257_0030	COG0758	DNA mediated transformation
PA257_0036	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PA257_0040	COG3119	arylsulfatase activity
PA257_0041	COG0583	DNA-binding transcription factor activity
PA257_0048	COG3360	Dodecin
PA257_0061	COG3174	membrane
PA257_0071	COG0367	asparagine synthase
PA257_0075	COG0583	DNA-binding transcription factor activity
PA257_0078	COG1764	response to oxidative stress
PA257_0085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PA257_0086	COG0339	signal peptide processing
PA257_0087	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PA257_0091	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PA257_0094	COG2815	serine threonine protein kinase
PA257_0094	COG0515	serine threonine protein kinase
PA257_0095	COG0631	protein serine/threonine phosphatase activity
PA257_0098	COG1360	Flagellar Motor Protein
PA257_0112	COG3501	Rhs element vgr protein
PA257_0117	COG3501	Rhs element vgr protein
PA257_0125	COG0659	secondary active sulfate transmembrane transporter activity
PA257_0128	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PA257_0129	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PA257_0130	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PA257_0138	COG2153	protein acetylation
PA257_0139	COG1733	regulation of RNA biosynthetic process
PA257_0146	COG0583	DNA-binding transcription factor activity
PA257_0151	COG2824	Alkylphosphonate utilization operon protein PhnA
PA257_0157	COG0402	S-adenosylhomocysteine deaminase activity
PA257_0168	COG3248	Nucleoside-binding outer membrane protein
PA257_0178	COG0583	DNA-binding transcription factor activity
PA257_0179	COG3485	protocatechuate 3,4-dioxygenase
PA257_0180	COG3485	protocatechuate 3,4-dioxygenase
PA257_0182	COG1414	Transcriptional regulator
PA257_0185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PA257_0186	COG0583	DNA-binding transcription factor activity
PA257_0193	COG2233	PERMEase
PA257_0194	COG1309	transcriptional regulator
PA257_0196	COG3706	GGDEF domain
PA257_0196	COG0745	RESPONSE REGULATOR receiver
PA257_0201	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PA257_0204	COG0835	chemotaxis
PA257_0205	COG0643	Histidine kinase
PA257_0205	COG2198	Histidine kinase
PA257_0206	COG0745	RESPONSE REGULATOR receiver
PA257_0208	COG0583	DNA-binding transcription factor activity
PA257_0209	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_0211	COG1116	anion transmembrane transporter activity
PA257_0212	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PA257_0213	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PA257_0221	COG2175	clavaminate synthase activity
PA257_0223	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PA257_0224	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PA257_0225	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PA257_0240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PA257_0246	COG1012	belongs to the aldehyde dehydrogenase family
PA257_0247	COG1113	amino acid transport
PA257_0250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PA257_0251	COG0235	Class ii aldolase
PA257_0252	COG1396	sequence-specific DNA binding
PA257_0253	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PA257_0254	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PA257_0256	COG0477	Major facilitator Superfamily
PA257_0258	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PA257_0259	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PA257_0260	COG0583	DNA-binding transcription factor activity
PA257_0264	COG0673	inositol 2-dehydrogenase activity
PA257_0268	COG2271	Major facilitator Superfamily
PA257_0270	COG1309	transcriptional regulator
PA257_0271	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PA257_0273	COG0477	Major facilitator Superfamily
PA257_0278	COG2239	Acts as a magnesium transporter
PA257_0281	COG1846	Transcriptional regulator
PA257_0295	COG3501	Rhs element vgr protein
PA257_0297	COG3316	Transposase and inactivated derivatives
PA257_0310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PA257_0318	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PA257_0319	COG4644	lycopene metabolic process
PA257_0320	COG0582	viral genome integration into host DNA
PA257_0331	COG0745	RESPONSE REGULATOR receiver
PA257_0333	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PA257_0336	COG0583	DNA-binding transcription factor activity
PA257_0337	COG2807	transmembrane transport
PA257_0341	COG0501	Belongs to the peptidase M48B family
PA257_0345	COG4208	sulfate ABC transporter
PA257_0347	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PA257_0356	COG3706	GGDEF domain
PA257_0361	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PA257_0362	COG0174	glutamine synthetase
PA257_0363	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PA257_0364	COG0174	glutamine synthetase
PA257_0368	COG3842	ATPase activity
PA257_0369	COG1176	ABC-type spermidine putrescine transport system, permease component I
PA257_0370	COG1177	transmembrane transport
PA257_0384	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PA257_0385	COG0277	FAD linked oxidase domain protein
PA257_0386	COG0179	Fumarylacetoacetate (FAA) hydrolase
PA257_0388	COG3111	PFAM Bacterial OB fold (BOF) protein
PA257_0390	COG0531	amino acid
PA257_0392	COG2182	Extracellular solute-binding protein
PA257_0393	COG1177	transmembrane transport
PA257_0394	COG1176	ABC-type spermidine putrescine transport system, permease component I
PA257_0395	COG3842	ATPase activity
PA257_0397	COG3204	pilus organization
PA257_0398	COG2234	aminopeptidase activity
PA257_0402	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PA257_0404	COG0702	epimerase
PA257_0410	COG3706	GGDEF domain
PA257_0412	COG0730	response to heat
PA257_0420	COG0584	glycerophosphoryl diester phosphodiesterase
PA257_0424	COG0622	Phosphoesterase
PA257_0425	COG2233	PERMEase
PA257_0429	COG0693	protein deglycase activity
PA257_0437	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PA257_0439	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PA257_0444	COG0429	hydrolase of the alpha beta-hydrolase fold
PA257_0446	COG0742	ribosomal rna small subunit methyltransferase
PA257_0447	COG0612	Peptidase, M16
PA257_0448	COG0612	Peptidase, M16
PA257_0449	COG0552	protein localization to endoplasmic reticulum
PA257_0450	COG2884	Cell division ATP-binding protein ftsE
PA257_0451	COG2177	Part of the ABC transporter FtsEX involved in
PA257_0455	COG2363	Small membrane protein
PA257_0462	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PA257_0465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PA257_0465	COG2813	Specifically methylates the guanine in position
PA257_0467	COG1160	GTP binding
PA257_0468	COG1872	DUF167
PA257_0496	COG4397	Mu-like prophage major head subunit gpT
PA257_0503	COG5005	Phage virion morphogenesis
PA257_0504	COG2369	cell adhesion
PA257_0505	COG4383	Mu-like prophage protein gp29
PA257_0523	COG4396	Host-nuclease inhibitor protein Gam
PA257_0535	COG0626	cystathionine gamma-synthase activity
PA257_0554	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PA257_0558	COG3038	cytochrome b561
PA257_0564	COG0513	Belongs to the DEAD box helicase family
PA257_0566	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PA257_0567	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PA257_0573	COG1309	transcriptional regulator
PA257_0574	COG0402	S-adenosylhomocysteine deaminase activity
PA257_0575	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PA257_0578	COG0493	'glutamate synthase
PA257_0582	COG1953	Uracil, thiamine, allantoin
PA257_0585	COG1960	acyl-CoA dehydrogenase activity
PA257_0586	COG0583	DNA-binding transcription factor activity
PA257_0588	COG0306	phosphate transporter
PA257_0590	COG0330	HflC and HflK could
PA257_0592	COG1289	transmembrane transporter activity
PA257_0593	COG0513	Belongs to the DEAD box helicase family
PA257_0595	COG0189	ligase activity
PA257_0595	COG4067	protein conserved in archaea
PA257_0596	COG0477	Major facilitator Superfamily
PA257_0598	COG0542	response to heat
PA257_0600	COG0204	Acyl-transferase
PA257_0602	COG0745	RESPONSE REGULATOR receiver
PA257_0603	COG2205	protein histidine kinase activity
PA257_0604	COG4452	Inner membrane protein CreD
PA257_0611	COG4774	siderophore transport
PA257_0612	COG3712	iron ion homeostasis
PA257_0613	COG0625	glutathione transferase activity
PA257_0615	COG1309	transcriptional regulator
PA257_0616	COG1953	Uracil, thiamine, allantoin
PA257_0620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PA257_0627	COG3585	molybdate ion transport
PA257_0627	COG2005	Transcriptional regulator
PA257_0628	COG5544	Lipoprotein
PA257_0629	COG1040	competence protein
PA257_0633	COG0511	ligase activity, forming carbon-carbon bonds
PA257_0636	COG1984	allophanate hydrolase subunit 2
PA257_0641	COG1073	alpha beta
PA257_0641	COG2226	methyltransferase
PA257_0646	COG1960	acyl-CoA dehydrogenase activity
PA257_0647	COG1960	acyl-CoA dehydrogenase activity
PA257_0649	COG1960	acyl-CoA dehydrogenase activity
PA257_0651	COG1648	precorrin-2 dehydrogenase activity
PA257_0651	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PA257_0668	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PA257_0669	COG0583	DNA-binding transcription factor activity
PA257_0670	COG2258	MOSC domain
PA257_0672	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PA257_0677	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PA257_0679	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PA257_0690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PA257_0691	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PA257_0693	COG3622	Belongs to the hyi family
PA257_0694	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PA257_0702	COG2081	HI0933 family
PA257_0703	COG1451	nucleotide metabolic process
PA257_0704	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PA257_0705	COG3152	Membrane
PA257_0706	COG4977	sequence-specific DNA binding
PA257_0706	COG1917	Cupin 2, conserved barrel domain protein
PA257_0707	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PA257_0727	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PA257_0730	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PA257_0734	COG2719	SpoVR family
PA257_0736	COG2766	serine protein kinase
PA257_0747	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PA257_0750	COG2197	response regulator
PA257_0752	COG3842	ATPase activity
PA257_0754	COG1176	ABC-type spermidine putrescine transport system, permease component I
PA257_0756	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PA257_0763	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PA257_0780	COG3179	chitinase
PA257_0788	COG1765	OsmC-like protein
PA257_0791	COG0537	adenosine 5'-monophosphoramidase activity
PA257_0802	COG0739	heme binding
PA257_0855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PA257_0862	COG2814	Major facilitator Superfamily
PA257_0867	COG1021	2,3-dihydroxybenzoate-AMP ligase
PA257_0869	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PA257_0869	COG2226	methyltransferase
PA257_0869	COG3433	isochorismatase activity
PA257_0870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PA257_0870	COG3433	isochorismatase activity
PA257_0870	COG2226	methyltransferase
PA257_0889	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PA257_0890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PA257_0892	COG2706	6-phosphogluconolactonase activity
PA257_0896	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PA257_0897	COG1960	acyl-CoA dehydrogenase activity
PA257_0899	COG4191	Histidine kinase
PA257_0900	COG4566	intracellular signal transduction
PA257_0902	COG1012	belongs to the aldehyde dehydrogenase family
PA257_0903	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PA257_0904	COG2271	Major facilitator Superfamily
PA257_0915	COG2226	methyltransferase
PA257_0917	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PA257_0920	COG0251	oxidation-reduction process
PA257_0922	COG0693	protein deglycase activity
PA257_0923	COG0492	ferredoxin-NADP+ reductase activity
PA257_0924	COG1959	2 iron, 2 sulfur cluster binding
PA257_0930	COG0154	amidase activity
PA257_0932	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PA257_0933	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PA257_0934	COG4592	Periplasmic binding protein
PA257_0935	COG1120	ATPase activity
PA257_0938	COG1629	transport
PA257_0938	COG4774	siderophore transport
PA257_0940	COG4991	sh3 domain protein
PA257_0941	COG1063	alcohol dehydrogenase
PA257_0943	COG0022	dehydrogenase e1 component
PA257_0944	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PA257_0945	COG3199	ATP-NAD kinase
PA257_0948	COG3284	Transcriptional regulator
PA257_0953	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PA257_0961	COG2814	Major facilitator Superfamily
PA257_0963	COG1846	Transcriptional regulator
PA257_0965	COG3278	Belongs to the heme-copper respiratory oxidase family
PA257_0966	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PA257_0969	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PA257_0972	COG3971	2-oxopent-4-enoate hydratase activity
PA257_0973	COG2271	Major facilitator Superfamily
PA257_0975	COG3384	dioxygenase
PA257_0976	COG1012	belongs to the aldehyde dehydrogenase family
PA257_0997	COG4397	Mu-like prophage major head subunit gpT
PA257_1002	COG4383	Mu-like prophage protein gp29
PA257_1003	COG4373	Mu-like prophage FluMu protein gp28
PA257_1005	COG0640	Transcriptional regulator
PA257_1019	COG0488	(ABC) transporter
PA257_1031	COG5566	PFAM Mor transcription activator
PA257_1036	COG1611	Belongs to the LOG family
PA257_1045	COG0583	DNA-binding transcription factor activity
PA257_1049	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_1050	COG1063	alcohol dehydrogenase
PA257_1051	COG2271	Major facilitator Superfamily
PA257_1058	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_1059	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PA257_1063	COG3121	Chaperone
PA257_1064	COG3188	usher protein
PA257_1068	COG2197	response regulator
PA257_1077	COG0531	amino acid
PA257_1081	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PA257_1082	COG3094	Invasion gene expression up-regulator, SirB
PA257_1083	COG3047	cAMP biosynthetic process
PA257_1089	COG3118	belongs to the thioredoxin family
PA257_1090	COG2264	protein methyltransferase activity
PA257_1094	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PA257_1094	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PA257_1099	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PA257_1100	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PA257_1102	COG3577	Aspartyl protease
PA257_1105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PA257_1107	COG0142	geranyltranstransferase activity
PA257_1109	COG4948	Mandelate Racemase Muconate Lactonizing
PA257_1113	COG1131	(ABC) transporter
PA257_1115	COG5002	protein histidine kinase activity
PA257_1119	COG0745	RESPONSE REGULATOR receiver
PA257_1121	COG3228	Belongs to the MtfA family
PA257_1122	COG0586	Pfam SNARE associated Golgi protein
PA257_1126	COG0456	acetyltransferase
PA257_1128	COG4303	Ethanolamine ammonia lyase large subunit
PA257_1129	COG0531	amino acid
PA257_1130	COG1012	belongs to the aldehyde dehydrogenase family
PA257_1131	COG3284	Transcriptional regulator
PA257_1132	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PA257_1135	COG0702	epimerase
PA257_1140	COG1346	cytolysis
PA257_1142	COG0586	Pfam SNARE associated Golgi protein
PA257_1150	COG0768	penicillin binding
PA257_1151	COG0772	Belongs to the SEDS family
PA257_1152	COG2951	lytic endotransglycosylase activity
PA257_1154	COG1686	Belongs to the peptidase S11 family
PA257_1160	COG2951	lytic endotransglycosylase activity
PA257_1167	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PA257_1169	COG4535	Mg2 and Co2 transporter CorC
PA257_1171	COG1702	phosphate starvation-inducible protein PhoH
PA257_1177	COG0351	phosphomethylpyrimidine kinase
PA257_1180	COG1960	acyl-CoA dehydrogenase activity
PA257_1182	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PA257_1193	COG1643	Atp-dependent helicase
PA257_1202	COG3416	Protein conserved in bacteria
PA257_1204	COG0513	Belongs to the DEAD box helicase family
PA257_1207	COG2197	response regulator
PA257_1209	COG2202	Pas domain
PA257_1209	COG2199	diguanylate cyclase activity
PA257_1209	COG2200	EAL domain
PA257_1210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PA257_1210	COG2205	protein histidine kinase activity
PA257_1214	COG1946	Acyl-CoA thioesterase
PA257_1218	COG4521	taurine ABC transporter
PA257_1220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PA257_1221	COG2175	clavaminate synthase activity
PA257_1222	COG1297	OPT oligopeptide transporter protein
PA257_1223	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PA257_1227	COG1271	oxidase subunit
PA257_1228	COG1294	oxidase, subunit
PA257_1230	COG2207	Transcriptional regulator
PA257_1232	COG0183	Belongs to the thiolase family
PA257_1233	COG0318	PFAM AMP-dependent synthetase and ligase
PA257_1241	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PA257_1246	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PA257_1248	COG0521	Mo-molybdopterin cofactor biosynthetic process
PA257_1249	COG0303	'Molybdopterin
PA257_1262	COG4772	TonB-dependent receptor
PA257_1263	COG3712	iron ion homeostasis
PA257_1264	COG1595	DNA-templated transcription, initiation
PA257_1266	COG0697	spore germination
PA257_1268	COG0583	DNA-binding transcription factor activity
PA257_1272	COG1566	PFAM secretion protein HlyD family protein
PA257_1282	COG0300	oxidoreductase activity
PA257_1283	COG2226	methyltransferase
PA257_1286	COG2197	response regulator
PA257_1287	COG3850	Histidine kinase
PA257_1290	COG2223	nitrite transmembrane transporter activity
PA257_1291	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PA257_1292	COG1140	nitrate reductase beta subunit
PA257_1293	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PA257_1294	COG2181	nitrate reductase activity
PA257_1295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PA257_1298	COG4771	TonB-dependent receptor
PA257_1299	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PA257_1305	COG0318	PFAM AMP-dependent synthetase and ligase
PA257_1307	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PA257_1320	COG0583	DNA-binding transcription factor activity
PA257_1323	COG0640	Transcriptional regulator
PA257_1327	COG0490	domain, Protein
PA257_1327	COG0471	metal ion transport
PA257_1328	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PA257_1329	COG4120	Belongs to the binding-protein-dependent transport system permease family
PA257_1338	COG0795	lipopolysaccharide-transporting ATPase activity
PA257_1339	COG0795	lipopolysaccharide-transporting ATPase activity
PA257_1341	COG2200	EAL domain
PA257_1346	COG1862	Preprotein translocase
PA257_1349	COG3134	Outer membrane lipoprotein
PA257_1352	COG1045	serine acetyltransferase
PA257_1370	COG0436	Aminotransferase
PA257_1373	COG0667	Aldo Keto reductase
PA257_1383	COG0739	heme binding
PA257_1385	COG2847	Copper chaperone PCu(A)C
PA257_1387	COG1335	isochorismatase
PA257_1390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PA257_1392	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PA257_1393	COG0583	DNA-binding transcription factor activity
PA257_1403	COG0582	viral genome integration into host DNA
PA257_1413	COG5489	Protein of unknown function (DUF736)
PA257_1420	COG1192	Involved in chromosome partitioning
PA257_1423	COG4959	Type IV secretory pathway protease TraF
PA257_1425	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PA257_1426	COG4605	iron ion homeostasis
PA257_1427	COG4604	ABC transporter, ATP-binding protein
PA257_1428	COG4607	ABC-type enterochelin transport system periplasmic component
PA257_1429	COG4773	Receptor
PA257_1430	COG2207	Transcriptional regulator
PA257_1431	COG2807	transmembrane transport
PA257_1433	COG0583	DNA-binding transcription factor activity
PA257_1437	COG4962	Type ii secretion system protein e
PA257_1438	COG3838	Conjugal transfer protein Trbc
PA257_1440	COG3451	type IV secretory pathway VirB4
PA257_1443	COG3846	protein secretion by the type IV secretion system
PA257_1448	COG2132	Multicopper oxidase
PA257_1449	COG0590	tRNA wobble adenosine to inosine editing
PA257_1458	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PA257_1458	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PA257_1459	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PA257_1460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PA257_1461	COG2188	Transcriptional regulator
PA257_1469	COG0477	Major facilitator Superfamily
PA257_1470	COG4536	flavin adenine dinucleotide binding
PA257_1473	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PA257_1478	COG1607	acyl-coa hydrolase
PA257_1482	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PA257_1487	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PA257_1492	COG2255	four-way junction helicase activity
PA257_1494	COG4681	YaeQ
PA257_1495	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PA257_1498	COG1902	pentaerythritol trinitrate reductase activity
PA257_1507	COG2197	response regulator
PA257_1508	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PA257_1512	COG0477	Major facilitator Superfamily
PA257_1519	COG3706	GGDEF domain
PA257_1519	COG5001	Diguanylate cyclase
PA257_1519	COG2203	Gaf domain
PA257_1519	COG4251	negative regulation of phosphorylation
PA257_1520	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PA257_1526	COG1073	alpha beta
PA257_1526	COG3064	Membrane
PA257_1526	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
PA257_1529	COG2885	chlorophyll binding
PA257_1532	COG0789	Transcriptional regulator
PA257_1536	COG1214	PFAM Peptidase M22, glycoprotease
PA257_1538	COG1801	Protein of unknown function DUF72
PA257_1539	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PA257_1544	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PA257_1553	COG2166	iron-sulfur cluster assembly
PA257_1556	COG1280	lysine exporter protein (LysE YggA)
PA257_1557	COG1393	Belongs to the ArsC family
PA257_1561	COG0025	NhaP-type Na H and K H
PA257_1562	COG0436	Aminotransferase
PA257_1564	COG0024	Methionine aminopeptidase
PA257_1580	COG1115	amino acid carrier protein
PA257_1590	COG2391	methyltransferase activity
PA257_1591	COG0583	DNA-binding transcription factor activity
PA257_1592	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PA257_1593	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PA257_1604	COG0582	viral genome integration into host DNA
PA257_1649	COG3179	chitinase
PA257_1656	COG1546	Belongs to the CinA family
PA257_1660	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PA257_1661	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PA257_1662	COG3530	Putative quorum-sensing-regulated virulence factor
PA257_1665	COG1177	transmembrane transport
PA257_1666	COG1176	ABC-type spermidine putrescine transport system, permease component I
PA257_1672	COG0069	glutamate synthase activity
PA257_1677	COG0531	amino acid
PA257_1678	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PA257_1678	COG2169	Transcriptional regulator
PA257_1679	COG0477	Major facilitator Superfamily
PA257_1681	COG0583	DNA-binding transcription factor activity
PA257_1682	COG1960	acyl-CoA dehydrogenase activity
PA257_1683	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PA257_1684	COG1024	Enoyl-CoA hydratase
PA257_1685	COG1250	3-hydroxyacyl-CoA dehydrogenase
PA257_1686	COG0183	Belongs to the thiolase family
PA257_1688	COG0583	DNA-binding transcription factor activity
PA257_1696	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PA257_1707	COG2814	Major facilitator Superfamily
PA257_1716	COG0583	DNA-binding transcription factor activity
PA257_1718	COG0084	hydrolase, TatD family'
PA257_1719	COG1609	Transcriptional regulator
PA257_1721	COG1105	Belongs to the carbohydrate kinase PfkB family
PA257_1722	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PA257_1722	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PA257_1722	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PA257_1745	COG3842	ATPase activity
PA257_1749	COG0243	molybdopterin cofactor binding
PA257_1750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PA257_1751	COG2223	nitrite transmembrane transporter activity
PA257_1753	COG2906	2 iron, 2 sulfur cluster binding
PA257_1754	COG0450	alkyl hydroperoxide reductase
PA257_1760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PA257_1769	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PA257_1770	COG2264	protein methyltransferase activity
PA257_1772	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PA257_1781	COG3501	Rhs element vgr protein
PA257_1787	COG0489	protein tyrosine kinase activity
PA257_1796	COG0791	NLP P60 protein
PA257_1800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PA257_1801	COG0668	transmembrane transport
PA257_1802	COG0477	Major facilitator Superfamily
PA257_1804	COG0513	Belongs to the DEAD box helicase family
PA257_1808	COG2205	protein histidine kinase activity
PA257_1808	COG0784	Response regulator, receiver
PA257_1808	COG5002	protein histidine kinase activity
PA257_1809	COG1363	Peptidase, m42
PA257_1811	COG0367	asparagine synthase
PA257_1817	COG0183	Belongs to the thiolase family
PA257_1821	COG0450	alkyl hydroperoxide reductase
PA257_1822	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PA257_1823	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PA257_1825	COG0431	NADPH-dependent FMN reductase
PA257_1826	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PA257_1828	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PA257_1833	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PA257_1838	COG0583	DNA-binding transcription factor activity
PA257_1839	COG1380	Effector of murein hydrolase LrgA
PA257_1840	COG1346	cytolysis
PA257_1844	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_1845	COG1024	Enoyl-CoA hydratase
PA257_1847	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
PA257_1864	COG1629	transport
PA257_1875	COG0583	DNA-binding transcription factor activity
PA257_1890	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PA257_1891	COG3639	organic phosphonate transmembrane transporter activity
PA257_1892	COG2188	Transcriptional regulator
PA257_1893	COG3624	Phosphonate C-P lyase system protein PhnG
PA257_1895	COG3626	phosphonate metabolism
PA257_1896	COG3627	carbon phosphorus lyase activity
PA257_1897	COG4107	phosphonate C-P lyase system protein PhnK
PA257_1898	COG4778	phosphonate C-P lyase system protein PhnL
PA257_1899	COG3454	Phosphonate metabolism
PA257_1901	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PA257_1914	COG1566	PFAM secretion protein HlyD family protein
PA257_1916	COG0697	spore germination
PA257_1922	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PA257_1926	COG0784	Response regulator, receiver
PA257_1926	COG0835	chemotaxis
PA257_1929	COG0745	RESPONSE REGULATOR receiver
PA257_1931	COG0514	ATP-dependent DNA helicase (RecQ)
PA257_1932	COG2203	Gaf domain
PA257_1932	COG4251	negative regulation of phosphorylation
PA257_1932	COG5001	Diguanylate cyclase
PA257_1932	COG3706	GGDEF domain
PA257_1937	COG1752	Esterase of the alpha-beta hydrolase superfamily
PA257_1945	COG2124	cytochrome p450
PA257_1946	COG4221	oxidoreductase activity
PA257_1955	COG0583	DNA-binding transcription factor activity
PA257_1961	COG3639	organic phosphonate transmembrane transporter activity
PA257_1963	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PA257_1964	COG2084	Dehydrogenase
PA257_1967	COG0589	response to stress
PA257_1977	COG2814	Major facilitator Superfamily
PA257_1978	COG2030	dehydratase
PA257_1979	COG2267	carboxylic ester hydrolase activity
PA257_1981	COG0318	PFAM AMP-dependent synthetase and ligase
PA257_1982	COG0318	PFAM AMP-dependent synthetase and ligase
PA257_1984	COG1643	Atp-dependent helicase
PA257_1986	COG0537	adenosine 5'-monophosphoramidase activity
PA257_1988	COG3501	Rhs element vgr protein
PA257_1997	COG1595	DNA-templated transcription, initiation
PA257_2013	COG1201	RNA secondary structure unwinding
PA257_2014	COG2205	protein histidine kinase activity
PA257_2017	COG4772	TonB-dependent receptor
PA257_2020	COG2076	Multidrug Resistance protein
PA257_2021	COG0385	Bile acid
PA257_2031	COG2200	EAL domain
PA257_2033	COG3321	synthase
PA257_2033	COG0604	alcohol dehydrogenase
PA257_2034	COG0560	Phosphoserine phosphatase
PA257_2037	COG1176	ABC-type spermidine putrescine transport system, permease component I
PA257_2043	COG0564	pseudouridine synthase activity
PA257_2045	COG2894	cell division
PA257_2047	COG1560	Kdo2-lipid A biosynthetic process
PA257_2050	COG2853	Lipoprotein
PA257_2055	COG3162	membrane
PA257_2056	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PA257_2062	COG1132	(ABC) transporter
PA257_2064	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PA257_2069	COG0509	glycine decarboxylation via glycine cleavage system
PA257_2070	COG0702	epimerase
PA257_2075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PA257_2078	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PA257_2078	COG0438	transferase activity, transferring glycosyl groups
PA257_2084	COG1127	ABC transporter
PA257_2085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PA257_2086	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PA257_2088	COG0778	Nitroreductase
PA257_2092	COG0745	RESPONSE REGULATOR receiver
PA257_2094	COG2350	Protein conserved in bacteria
PA257_2096	COG0613	PHP domain protein
PA257_2097	COG0009	L-threonylcarbamoyladenylate synthase
PA257_2099	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PA257_2106	COG0745	RESPONSE REGULATOR receiver
PA257_2107	COG2205	protein histidine kinase activity
PA257_2110	COG0395	ABC-type sugar transport system, permease component
PA257_2111	COG3842	ATPase activity
PA257_2115	COG0676	glucose-6-phosphate 1-epimerase activity
PA257_2123	COG3706	GGDEF domain
PA257_2125	COG0786	glutamate:sodium symporter activity
PA257_2128	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_2131	COG0402	S-adenosylhomocysteine deaminase activity
PA257_2137	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PA257_2145	COG1086	Polysaccharide biosynthesis protein
PA257_2157	COG0583	DNA-binding transcription factor activity
PA257_2164	COG0596	Alpha beta hydrolase
PA257_2165	COG0800	Aldolase
PA257_2168	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_2172	COG0583	DNA-binding transcription factor activity
PA257_2173	COG0251	oxidation-reduction process
PA257_2177	COG2226	methyltransferase
PA257_2185	COG0285	dihydrofolate synthase activity
PA257_2186	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PA257_2187	COG1286	toxin biosynthetic process
PA257_2209	COG0446	pyridine nucleotide-disulphide oxidoreductase
PA257_2209	COG1902	pentaerythritol trinitrate reductase activity
PA257_2214	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PA257_2216	COG3139	Protein of unknown function (DUF1315)
PA257_2218	COG0308	aminopeptidase N
PA257_2224	COG5002	protein histidine kinase activity
PA257_2225	COG0745	RESPONSE REGULATOR receiver
PA257_2232	COG0714	Associated with various cellular activities
PA257_2235	COG2342	PFAM TM1410 hypothetical-related protein
PA257_2240	COG0297	glycogen (starch) synthase activity
PA257_2252	COG2027	D-alanyl-D-alanine carboxypeptidase
PA257_2253	COG3171	Protein conserved in bacteria
PA257_2254	COG2197	response regulator
PA257_2255	COG2205	protein histidine kinase activity
PA257_2255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PA257_2261	COG0004	ammonium transporteR
PA257_2263	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PA257_2265	COG0625	glutathione transferase activity
PA257_2266	COG1309	transcriptional regulator
PA257_2272	COG0521	Mo-molybdopterin cofactor biosynthetic process
PA257_2277	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PA257_2278	COG1070	Carbohydrate kinase
PA257_2282	COG0741	lytic transglycosylase activity
PA257_2286	COG0589	response to stress
PA257_2301	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PA257_2303	COG1113	amino acid transport
PA257_2310	COG1477	protein flavinylation
PA257_2313	COG0584	glycerophosphoryl diester phosphodiesterase
PA257_2316	COG4591	ABC-type transport system involved in lipoprotein release permease component
PA257_2318	COG4591	ABC-type transport system involved in lipoprotein release permease component
PA257_2320	COG2333	competence protein COMEC
PA257_2320	COG0658	competence protein
PA257_2321	COG0811	peptide transport
PA257_2322	COG0848	biopolymer transport protein
PA257_2326	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PA257_2328	COG1530	ribonuclease E activity
PA257_2332	COG0616	signal peptide processing
PA257_2332	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PA257_2334	COG1399	metal-binding, possibly nucleic acid-binding protein
PA257_2341	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PA257_2343	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PA257_2347	COG0084	hydrolase, TatD family'
PA257_2365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PA257_2369	COG0183	Belongs to the thiolase family
PA257_2371	COG2233	PERMEase
PA257_2376	COG2814	Major facilitator Superfamily
PA257_2377	COG1902	pentaerythritol trinitrate reductase activity
PA257_2378	COG1309	transcriptional regulator
PA257_2385	COG4160	amino acid transport
PA257_2386	COG4215	(ABC) transporter
PA257_2387	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PA257_2388	COG1473	amidohydrolase
PA257_2389	COG0583	DNA-binding transcription factor activity
PA257_2390	COG0840	transmembrane signaling receptor activity
PA257_2396	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PA257_2398	COG1120	ATPase activity
PA257_2404	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PA257_2410	COG3047	cAMP biosynthetic process
PA257_2410	COG2885	chlorophyll binding
PA257_2411	COG2197	response regulator
PA257_2413	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PA257_2414	COG1595	DNA-templated transcription, initiation
PA257_2420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PA257_2421	COG1960	acyl-CoA dehydrogenase activity
PA257_2422	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PA257_2425	COG1309	transcriptional regulator
PA257_2431	COG0583	DNA-binding transcription factor activity
PA257_2433	COG0583	DNA-binding transcription factor activity
PA257_2435	COG0714	Associated with various cellular activities
PA257_2440	COG3706	GGDEF domain
PA257_2444	COG0084	hydrolase, TatD family'
PA257_2446	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PA257_2447	COG2259	Doxx family
PA257_2451	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PA257_2454	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PA257_2455	COG4181	ATPase activity
PA257_2463	COG1764	response to oxidative stress
PA257_2464	COG1846	Transcriptional regulator
PA257_2465	COG0583	DNA-binding transcription factor activity
PA257_2467	COG0583	DNA-binding transcription factor activity
PA257_2469	COG3214	Protein conserved in bacteria
PA257_2470	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PA257_2473	COG1024	Enoyl-CoA hydratase
PA257_2478	COG3384	dioxygenase
PA257_2486	COG2866	Carboxypeptidase
PA257_2489	COG0436	Aminotransferase
PA257_2491	COG0386	Belongs to the glutathione peroxidase family
PA257_2492	COG1846	Transcriptional regulator
PA257_2493	COG5002	protein histidine kinase activity
PA257_2493	COG2205	protein histidine kinase activity
PA257_2493	COG0784	Response regulator, receiver
PA257_2494	COG2255	four-way junction helicase activity
PA257_2495	COG1956	GAF domain-containing protein
PA257_2496	COG0625	glutathione transferase activity
PA257_2500	COG0582	viral genome integration into host DNA
PA257_2501	COG0583	DNA-binding transcription factor activity
PA257_2526	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PA257_2527	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PA257_2528	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PA257_2531	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PA257_2532	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PA257_2534	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PA257_2537	COG3588	fructose-bisphosphate aldolase
PA257_2539	COG1126	abc transporter atp-binding protein
PA257_2542	COG2207	Transcriptional regulator
PA257_2544	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PA257_2549	COG0018	arginyl-trna synthetase
PA257_2552	COG2963	transposase activity
PA257_2555	COG3039	Transposase
PA257_2560	COG0183	Belongs to the thiolase family
PA257_2562	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PA257_2574	COG0625	glutathione transferase activity
PA257_2575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PA257_2576	COG0583	DNA-binding transcription factor activity
PA257_2582	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PA257_2584	COG0789	Transcriptional regulator
PA257_2598	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PA257_2603	COG0018	arginyl-trna synthetase
PA257_2606	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PA257_2633	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PA257_2635	COG0629	single-stranded DNA binding
PA257_2642	COG1192	Involved in chromosome partitioning
PA257_2661	COG0625	glutathione transferase activity
PA257_2662	COG1131	(ABC) transporter
PA257_2663	COG0842	Transport permease protein
PA257_2672	COG2188	Transcriptional regulator
PA257_2674	COG2853	Lipoprotein
PA257_2676	COG0745	RESPONSE REGULATOR receiver
PA257_2692	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PA257_2699	COG3728	DNA packaging
PA257_2699	COG5484	DNA packaging
PA257_2722	COG3617	BRO family, N-terminal domain
PA257_2726	COG3179	chitinase
PA257_2742	COG0840	transmembrane signaling receptor activity
PA257_2745	COG3655	Transcriptional regulator
PA257_2753	COG2116	formate transmembrane transporter activity
PA257_2754	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PA257_2764	COG1051	belongs to the nudix hydrolase family
PA257_2766	COG1024	Enoyl-CoA hydratase
PA257_2766	COG1250	3-hydroxyacyl-CoA dehydrogenase
PA257_2768	COG2837	iron assimilation
PA257_2785	COG1238	metal cluster binding
PA257_2787	COG1295	ribonuclease BN
PA257_2793	COG0024	Methionine aminopeptidase
PA257_2809	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PA257_2811	COG2189	Belongs to the N(4) N(6)-methyltransferase family
PA257_2813	COG2801	Transposase and inactivated derivatives
PA257_2814	COG2963	transposase activity
PA257_2818	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PA257_2818	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PA257_2820	COG0542	response to heat
PA257_2829	COG0789	Transcriptional regulator
PA257_2831	COG1902	pentaerythritol trinitrate reductase activity
PA257_2831	COG0446	pyridine nucleotide-disulphide oxidoreductase
PA257_2832	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PA257_2833	COG0243	molybdopterin cofactor binding
PA257_2834	COG1733	regulation of RNA biosynthetic process
PA257_2838	COG1280	lysine exporter protein (LysE YggA)
PA257_2839	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PA257_2841	COG0542	response to heat
PA257_2857	COG1607	acyl-coa hydrolase
PA257_2858	COG1959	2 iron, 2 sulfur cluster binding
PA257_2861	COG2819	hydrolase of the alpha beta superfamily
PA257_2866	COG3501	Rhs element vgr protein
PA257_2867	COG3209	COG3209 Rhs family protein
PA257_2871	COG0583	DNA-binding transcription factor activity
PA257_2873	COG4106	trans-aconitate 2-methyltransferase activity
PA257_2875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PA257_2876	COG1459	type II secretion system
PA257_2886	COG0720	synthase
PA257_2887	COG3604	Transcriptional regulator
PA257_2896	COG0745	RESPONSE REGULATOR receiver
PA257_2899	COG0840	transmembrane signaling receptor activity
PA257_2901	COG2056	Na+-H+ antiporter family
PA257_2904	COG2226	methyltransferase
PA257_2924	COG2153	protein acetylation
PA257_2925	COG2850	peptidyl-arginine hydroxylation
PA257_2933	COG1278	Cold shock
PA257_2935	COG0542	response to heat
PA257_2936	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PA257_2939	COG0492	ferredoxin-NADP+ reductase activity
PA257_2943	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PA257_2946	COG0435	Glutathione S-transferase
PA257_2947	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PA257_2948	COG2920	part of a sulfur-relay system
PA257_2956	COG0583	DNA-binding transcription factor activity
PA257_2958	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PA257_2960	COG1960	acyl-CoA dehydrogenase activity
PA257_2961	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PA257_2963	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PA257_2967	COG2197	response regulator
PA257_2979	COG2205	protein histidine kinase activity
PA257_2979	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PA257_2983	COG2249	NAD(P)H dehydrogenase (quinone) activity
PA257_2986	COG1522	sequence-specific DNA binding
PA257_2992	COG4191	Histidine kinase
PA257_2998	COG4251	negative regulation of phosphorylation
PA257_2998	COG2203	Gaf domain
PA257_2998	COG3706	GGDEF domain
PA257_2998	COG5001	Diguanylate cyclase
PA257_3003	COG0659	secondary active sulfate transmembrane transporter activity
PA257_3011	COG0318	PFAM AMP-dependent synthetase and ligase
PA257_3013	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PA257_3015	COG0183	Belongs to the thiolase family
PA257_3016	COG1960	acyl-CoA dehydrogenase activity
PA257_3023	COG0346	lactoylglutathione lyase activity
PA257_3024	COG0708	Exodeoxyribonuclease III
PA257_3026	COG0729	surface antigen
PA257_3028	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PA257_3029	COG2267	carboxylic ester hydrolase activity
PA257_3030	COG0671	phosphoesterase, PA-phosphatase related
PA257_3030	COG2453	phosphatase
PA257_3033	COG4589	Belongs to the CDS family
PA257_3034	COG0667	Aldo Keto reductase
PA257_3036	COG1115	amino acid carrier protein
PA257_3043	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PA257_3044	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PA257_3045	COG1538	Outer membrane efflux protein
PA257_3057	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PA257_3057	COG0543	2 iron, 2 sulfur cluster binding
PA257_3058	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PA257_3059	COG4638	Rieske (2fe-2S)
PA257_3064	COG4948	Mandelate Racemase Muconate Lactonizing
PA257_3066	COG3485	protocatechuate 3,4-dioxygenase
PA257_3073	COG2807	transmembrane transport
PA257_3074	COG0590	tRNA wobble adenosine to inosine editing
PA257_3077	COG2318	DinB family
PA257_3090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PA257_3091	COG2863	cytochrome
PA257_3092	COG3258	Cytochrome c
PA257_3094	COG0642	Histidine kinase
PA257_3095	COG0745	RESPONSE REGULATOR receiver
PA257_3101	COG0625	glutathione transferase activity
PA257_3105	COG0583	DNA-binding transcription factor activity
PA257_3106	COG1595	DNA-templated transcription, initiation
PA257_3107	COG3712	iron ion homeostasis
PA257_3120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PA257_3122	COG2382	esterase
PA257_3141	COG4397	Mu-like prophage major head subunit gpT
PA257_3148	COG5005	Phage virion morphogenesis
PA257_3149	COG2369	cell adhesion
PA257_3150	COG4383	Mu-like prophage protein gp29
PA257_3168	COG4396	Host-nuclease inhibitor protein Gam
PA257_3182	COG0583	DNA-binding transcription factor activity
PA257_3186	COG1760	l-serine dehydratase
PA257_3187	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PA257_3194	COG2217	Heavy metal translocating P-type atpase
PA257_3197	COG0583	DNA-binding transcription factor activity
PA257_3201	COG1566	PFAM secretion protein HlyD family protein
PA257_3221	COG1335	isochorismatase
PA257_3223	COG0583	DNA-binding transcription factor activity
PA257_3231	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PA257_3232	COG1121	(ABC) transporter
PA257_3241	COG4774	siderophore transport
PA257_3251	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PA257_3256	COG0735	belongs to the Fur family
PA257_3258	COG1304	FMN binding
PA257_3265	COG4566	intracellular signal transduction
PA257_3268	COG3501	Rhs element vgr protein
PA257_3284	COG3829	transcription factor binding
PA257_3290	COG3829	transcription factor binding
PA257_3291	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PA257_3292	COG0584	glycerophosphoryl diester phosphodiesterase
PA257_3293	COG2011	ABC-type metal ion transport system permease component
PA257_3295	COG1464	Belongs to the NlpA lipoprotein family
PA257_3301	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PA257_3302	COG1070	Carbohydrate kinase
PA257_3303	COG0246	Mannitol dehydrogenase
PA257_3306	COG1175	transmembrane transport
PA257_3309	COG1917	Cupin 2, conserved barrel domain protein
PA257_3309	COG4977	sequence-specific DNA binding
PA257_3312	COG1116	anion transmembrane transporter activity
PA257_3313	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PA257_3314	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PA257_3318	COG1012	belongs to the aldehyde dehydrogenase family
PA257_3321	COG3265	gluconokinase activity
PA257_3322	COG1609	Transcriptional regulator
PA257_3324	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PA257_3325	COG0583	DNA-binding transcription factor activity
PA257_3331	COG1396	sequence-specific DNA binding
PA257_3334	COG2175	clavaminate synthase activity
PA257_3336	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PA257_3337	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PA257_3342	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PA257_3342	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PA257_3344	COG3469	chitinase activity
PA257_3346	COG1053	succinate dehydrogenase
PA257_3355	COG4772	TonB-dependent receptor
PA257_3364	COG0431	NADPH-dependent FMN reductase
PA257_3365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PA257_3367	COG0640	Transcriptional regulator
PA257_3368	COG2207	Transcriptional regulator
PA257_3369	COG1064	alcohol dehydrogenase
PA257_3374	COG1309	transcriptional regulator
PA257_3376	COG0504	CTP synthase activity
PA257_3383	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PA257_3385	COG1609	Transcriptional regulator
PA257_3393	COG0252	asparaginase activity
PA257_3394	COG1115	amino acid carrier protein
PA257_3406	COG0728	peptidoglycan biosynthetic process
PA257_3419	COG2258	MOSC domain
PA257_3474	COG4644	lycopene metabolic process
PA257_3480	COG2801	Transposase and inactivated derivatives
PA257_3481	COG2963	transposase activity
PA257_3483	COG2508	Transcriptional regulator
PA257_3485	COG4447	cellulose binding
PA257_3486	COG2409	Drug exporters of the RND superfamily
PA257_3490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PA257_3493	COG2072	flavoprotein involved in K transport
PA257_3496	COG0531	amino acid
PA257_3497	COG1012	belongs to the aldehyde dehydrogenase family
PA257_3498	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PA257_3501	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PA257_3502	COG3162	membrane
PA257_3503	COG0318	PFAM AMP-dependent synthetase and ligase
PA257_3504	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_3510	COG3008	intermembrane lipid transfer
PA257_3511	COG2995	paraquat-inducible protein a
PA257_3512	COG1012	belongs to the aldehyde dehydrogenase family
PA257_3514	COG4948	Mandelate Racemase Muconate Lactonizing
PA257_3515	COG2271	Major facilitator Superfamily
PA257_3518	COG3618	amidohydrolase
PA257_3519	COG2271	Major facilitator Superfamily
PA257_3526	COG0765	amino acid transport
PA257_3527	COG0765	amino acid transport
PA257_3530	COG2084	Dehydrogenase
PA257_3532	COG2130	NADP-dependent
PA257_3533	COG1309	transcriptional regulator
PA257_3538	COG0517	IMP dehydrogenase activity
PA257_3545	COG2890	protein-(glutamine-N5) methyltransferase activity
PA257_3548	COG0784	Response regulator, receiver
PA257_3548	COG4191	Histidine kinase
PA257_3554	COG1363	Peptidase, m42
PA257_3562	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PA257_3571	COG3568	Endonuclease Exonuclease Phosphatase
PA257_3572	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PA257_3573	COG0392	lysyltransferase activity
PA257_3575	COG0366	Alpha amylase catalytic
PA257_3579	COG1285	pathogenesis
PA257_3585	COG0058	SHG alpha-glucan phosphorylase activity
PA257_3588	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_3589	COG1546	Belongs to the CinA family
PA257_3595	COG2323	membrane
PA257_3599	COG3121	Chaperone
PA257_3601	COG3188	usher protein
PA257_3602	COG3121	Chaperone
PA257_3605	COG3969	phosphoadenosine phosphosulfate
PA257_3607	COG1475	DNA binding
PA257_3609	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PA257_3610	COG0583	DNA-binding transcription factor activity
PA257_3618	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PA257_3618	COG2169	Transcriptional regulator
PA257_3622	COG0583	DNA-binding transcription factor activity
PA257_3628	COG1984	allophanate hydrolase subunit 2
PA257_3630	COG0028	Belongs to the TPP enzyme family
PA257_3632	COG0300	oxidoreductase activity
PA257_3639	COG2814	Major facilitator Superfamily
PA257_3641	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PA257_3645	COG0596	Alpha beta hydrolase
PA257_3646	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PA257_3647	COG0367	asparagine synthase
PA257_3649	COG1522	sequence-specific DNA binding
PA257_3653	COG1113	amino acid transport
PA257_3655	COG2010	Cytochrome c
PA257_3656	COG2010	Cytochrome c
PA257_3660	COG5001	Diguanylate cyclase
PA257_3664	COG2192	nodulation
PA257_3665	COG2814	Major facilitator Superfamily
PA257_3671	COG1104	cysteine desulfurase activity
PA257_3672	COG4172	Belongs to the ABC transporter superfamily
PA257_3673	COG4239	(ABC) transporter, permease
PA257_3674	COG4174	ABC transporter (Permease)
PA257_3676	COG4771	TonB-dependent receptor
PA257_3679	COG0583	DNA-binding transcription factor activity
PA257_3683	COG1595	DNA-templated transcription, initiation
PA257_3687	COG2207	Transcriptional regulator
PA257_3692	COG0564	pseudouridine synthase activity
PA257_3695	COG0531	amino acid
PA257_3696	COG0174	glutamine synthetase
PA257_3701	COG0028	Belongs to the TPP enzyme family
PA257_3704	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PA257_3709	COG1522	sequence-specific DNA binding
PA257_3717	COG1309	transcriptional regulator
PA257_3718	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PA257_3719	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PA257_3721	COG3204	pilus organization
PA257_3722	COG0789	Transcriptional regulator
PA257_3723	COG1960	acyl-CoA dehydrogenase activity
PA257_3725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PA257_3731	COG0179	Fumarylacetoacetate (FAA) hydrolase
PA257_3733	COG2271	Major facilitator Superfamily
PA257_3734	COG3290	protein histidine kinase activity
PA257_3734	COG3829	transcription factor binding
PA257_3735	COG2610	gluconate transmembrane transporter activity
PA257_3736	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_3737	COG2031	fatty acid transporter
PA257_3740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PA257_3741	COG0583	DNA-binding transcription factor activity
PA257_3742	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PA257_3743	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PA257_3747	COG2205	protein histidine kinase activity
PA257_3756	COG1012	belongs to the aldehyde dehydrogenase family
PA257_3761	COG3851	Histidine kinase
PA257_3765	COG0784	Response regulator, receiver
PA257_3765	COG2205	protein histidine kinase activity
PA257_3769	COG2194	sulfuric ester hydrolase activity
PA257_3778	COG0488	(ABC) transporter
PA257_3781	COG0583	DNA-binding transcription factor activity
PA257_3782	COG1278	Cold shock
PA257_3792	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PA257_3793	COG1609	Transcriptional regulator
PA257_3794	COG1172	Belongs to the binding-protein-dependent transport system permease family
PA257_3795	COG1129	ABC transporter
PA257_3796	COG1879	ABC-type sugar transport system periplasmic component
PA257_3798	COG2204	response regulator
PA257_3802	COG2010	Cytochrome c
PA257_3803	COG0753	catalase activity
PA257_3808	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PA257_3809	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PA257_3810	COG2080	2 iron, 2 sulfur cluster binding
PA257_3815	COG1944	ATP diphosphatase activity
PA257_3820	COG4771	TonB-dependent receptor
PA257_3823	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PA257_3823	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PA257_3826	COG0579	oxidoreductase
PA257_3834	COG1595	DNA-templated transcription, initiation
PA257_3835	COG3712	iron ion homeostasis
PA257_3839	COG2814	Major facilitator Superfamily
PA257_3849	COG2197	response regulator
PA257_3855	COG2366	antibiotic biosynthetic process
PA257_3858	COG0625	glutathione transferase activity
PA257_3863	COG0417	DNA replication proofreading
PA257_3872	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PA257_3888	COG1309	transcriptional regulator
PA257_3892	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PA257_3893	COG0583	DNA-binding transcription factor activity
PA257_3895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PA257_3896	COG2354	Protein conserved in bacteria
PA257_3898	COG3278	Belongs to the heme-copper respiratory oxidase family
PA257_3900	COG2239	Acts as a magnesium transporter
PA257_3903	COG5001	Diguanylate cyclase
PA257_3903	COG4251	negative regulation of phosphorylation
PA257_3903	COG3706	GGDEF domain
PA257_3903	COG2203	Gaf domain
PA257_3905	COG4977	sequence-specific DNA binding
PA257_3906	COG3813	Protein conserved in bacteria
PA257_3920	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PA257_3925	COG0604	alcohol dehydrogenase
PA257_3926	COG0616	signal peptide processing
PA257_3930	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_3931	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_3932	COG0583	DNA-binding transcription factor activity
PA257_3937	COG1024	Enoyl-CoA hydratase
PA257_3940	COG0531	amino acid
PA257_3941	COG1982	Orn Lys Arg decarboxylase major
PA257_3943	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PA257_3947	COG1388	LysM domain
PA257_3947	COG0741	lytic transglycosylase activity
PA257_3948	COG4166	transmembrane transport
PA257_3949	COG4166	transmembrane transport
PA257_3950	COG4174	ABC transporter (Permease)
PA257_3951	COG4239	(ABC) transporter, permease
PA257_3952	COG4172	Belongs to the ABC transporter superfamily
PA257_3954	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PA257_3957	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PA257_3962	COG0745	RESPONSE REGULATOR receiver
PA257_3963	COG2205	protein histidine kinase activity
PA257_3964	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PA257_3976	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PA257_3980	COG0589	response to stress
PA257_3985	COG2201	protein-glutamate methylesterase activity
PA257_3988	COG2223	nitrite transmembrane transporter activity
PA257_3989	COG0515	serine threonine protein kinase
PA257_3990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PA257_3991	COG2146	nitrite reductase [NAD(P)H] activity
PA257_3992	COG0243	molybdopterin cofactor binding
PA257_3996	COG0668	transmembrane transport
PA257_4004	COG0189	ligase activity
PA257_4004	COG4067	protein conserved in archaea
PA257_4013	COG2909	trisaccharide binding
PA257_4014	COG2909	trisaccharide binding
PA257_4022	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PA257_4024	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PA257_4032	COG0519	Catalyzes the synthesis of GMP from XMP
PA257_4035	COG0667	Aldo Keto reductase
PA257_4038	COG0183	Belongs to the thiolase family
PA257_4042	COG1305	Transglutaminase-like
PA257_4044	COG2308	Evidence 4 Homologs of previously reported genes of
PA257_4049	COG1317	bacterial-type flagellum organization
PA257_4071	COG4789	Type iii secretion
PA257_4080	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PA257_4081	COG4790	Type iii secretion
PA257_4082	COG4794	Type iii secretion
PA257_4083	COG4791	protein targeting
PA257_4084	COG4792	protein secretion
PA257_4104	COG0515	serine threonine protein kinase
PA257_4104	COG2815	serine threonine protein kinase
PA257_4105	COG0631	protein serine/threonine phosphatase activity
PA257_4112	COG2204	response regulator
PA257_4121	COG3501	Rhs element vgr protein
PA257_4123	COG3209	COG3209 Rhs family protein
PA257_4125	COG0625	glutathione transferase activity
PA257_4126	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PA257_4129	COG3135	benzoate transporter
PA257_4132	COG2130	NADP-dependent
PA257_4135	COG0840	transmembrane signaling receptor activity
PA257_4137	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PA257_4145	COG0745	RESPONSE REGULATOR receiver
PA257_4146	COG2205	protein histidine kinase activity
PA257_4151	COG1960	acyl-CoA dehydrogenase activity
PA257_4153	COG1024	Enoyl-CoA hydratase
PA257_4154	COG1250	3-hydroxyacyl-CoA dehydrogenase
PA257_4155	COG2186	Transcriptional regulator
PA257_4156	COG2807	transmembrane transport
PA257_4157	COG0628	permease
PA257_4159	COG0625	glutathione transferase activity
PA257_4165	COG1022	Amp-dependent synthetase and ligase
PA257_4171	COG0784	Response regulator, receiver
PA257_4171	COG5002	protein histidine kinase activity
PA257_4171	COG2205	protein histidine kinase activity
PA257_4179	COG1846	Transcriptional regulator
PA257_4180	COG2080	2 iron, 2 sulfur cluster binding
PA257_4181	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PA257_4181	COG2010	Cytochrome c
PA257_4182	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PA257_4182	COG2010	Cytochrome c
PA257_4183	COG2207	Transcriptional regulator
PA257_4199	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PA257_4200	COG1053	succinate dehydrogenase
PA257_4201	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PA257_4202	COG2009	succinate dehydrogenase
PA257_4208	COG2084	Dehydrogenase
PA257_4211	COG3738	Protein conserved in bacteria
PA257_4218	COG0251	oxidation-reduction process
PA257_4219	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PA257_4220	COG0174	glutamine synthetase
PA257_4221	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PA257_4225	COG0840	transmembrane signaling receptor activity
PA257_4228	COG3278	Belongs to the heme-copper respiratory oxidase family
PA257_4231	COG2010	Cytochrome c
PA257_4232	COG3278	Belongs to the heme-copper respiratory oxidase family
PA257_4235	COG2010	Cytochrome c
PA257_4237	COG0348	domain, Protein
PA257_4239	COG2217	Heavy metal translocating P-type atpase
PA257_4247	COG2076	Multidrug Resistance protein
PA257_4253	COG1960	acyl-CoA dehydrogenase activity
PA257_4256	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PA257_4261	COG1196	nuclear chromosome segregation
PA257_4268	COG0402	S-adenosylhomocysteine deaminase activity
PA257_4271	COG2252	PERMEase
PA257_4280	COG3501	Rhs element vgr protein
PA257_4286	COG2233	PERMEase
PA257_4289	COG1309	transcriptional regulator
PA257_4291	COG3960	tartronate-semialdehyde synthase activity
PA257_4292	COG3622	Belongs to the hyi family
PA257_4293	COG2084	Dehydrogenase
PA257_4295	COG0469	pyruvate kinase activity
PA257_4296	COG4413	Urea transporter
PA257_4297	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PA257_4300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PA257_4302	COG3192	ethanolamine utilization protein
PA257_4305	COG0446	pyridine nucleotide-disulphide oxidoreductase
PA257_4306	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PA257_4309	COG2197	response regulator
PA257_4321	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PA257_4323	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_4329	COG0835	chemotaxis
PA257_4331	COG1192	Involved in chromosome partitioning
PA257_4332	COG1360	Flagellar Motor Protein
PA257_4333	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PA257_4335	COG2198	Histidine kinase
PA257_4335	COG0643	Histidine kinase
PA257_4339	COG0455	bacterial-type flagellum organization
PA257_4341	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PA257_4342	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PA257_4346	COG1987	bacterial-type flagellum assembly
PA257_4354	COG2832	Protein of unknown function (DUF454)
PA257_4357	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PA257_4358	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PA257_4360	COG3300	MHYT domain
PA257_4360	COG5001	Diguanylate cyclase
PA257_4381	COG0583	DNA-binding transcription factor activity
PA257_4384	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PA257_4387	COG3264	Mechanosensitive ion channel
PA257_4387	COG1196	nuclear chromosome segregation
PA257_4388	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PA257_4388	COG0116	Belongs to the methyltransferase superfamily
PA257_4390	COG0210	DNA helicase
PA257_4395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PA257_4405	COG0438	transferase activity, transferring glycosyl groups
PA257_4406	COG0463	Glycosyl transferase, family 2
PA257_4407	COG0438	transferase activity, transferring glycosyl groups
PA257_4414	COG1450	Type ii and iii secretion system protein
PA257_4416	COG2207	Transcriptional regulator
PA257_4417	COG4221	oxidoreductase activity
PA257_4419	COG1247	-acetyltransferase
PA257_4422	COG1733	regulation of RNA biosynthetic process
PA257_4423	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PA257_4425	COG0384	phenazine biosynthesis protein PhzF
PA257_4431	COG5006	permease, DMT superfamily
PA257_4434	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PA257_4437	COG3795	YCII-related domain
PA257_4440	COG2814	Major facilitator Superfamily
PA257_4441	COG4941	Belongs to the sigma-70 factor family
PA257_4444	COG3795	YCII-related domain
PA257_4446	COG2197	response regulator
PA257_4447	COG1982	Orn Lys Arg decarboxylase major
PA257_4448	COG0189	ligase activity
PA257_4449	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_4452	COG0765	amino acid transport
PA257_4453	COG0765	amino acid transport
PA257_4454	COG1126	abc transporter atp-binding protein
PA257_4460	COG1902	pentaerythritol trinitrate reductase activity
PA257_4464	COG1253	flavin adenine dinucleotide binding
PA257_4465	COG0300	oxidoreductase activity
PA257_4467	COG0583	DNA-binding transcription factor activity
PA257_4468	COG1864	DNA RNA non-specific endonuclease
PA257_4468	COG3591	Belongs to the peptidase S1B family
PA257_4469	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PA257_4470	COG4319	ketosteroid isomerase
PA257_4473	COG4774	siderophore transport
PA257_4484	COG2814	Major facilitator Superfamily
PA257_4488	COG0583	DNA-binding transcription factor activity
PA257_4490	COG0121	glutamine amidotransferase
PA257_4496	COG3712	iron ion homeostasis
PA257_4497	COG1595	DNA-templated transcription, initiation
PA257_4500	COG1230	cation diffusion facilitator family transporter
PA257_4501	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PA257_4514	COG1960	acyl-CoA dehydrogenase activity
PA257_4518	COG0406	alpha-ribazole phosphatase activity
PA257_4524	COG0778	Nitroreductase
PA257_4527	COG4206	TonB-dependent receptor
PA257_4529	COG1802	Transcriptional regulator
PA257_4531	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PA257_4537	COG0477	Major facilitator Superfamily
PA257_4541	COG0765	amino acid transport
PA257_4543	COG1126	abc transporter atp-binding protein
PA257_4545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PA257_4546	COG1012	belongs to the aldehyde dehydrogenase family
PA257_4557	COG4191	Histidine kinase
PA257_4557	COG0784	Response regulator, receiver
PA257_4566	COG2207	Transcriptional regulator
PA257_4569	COG1289	transmembrane transporter activity
PA257_4572	COG2207	Transcriptional regulator
PA257_4576	COG2249	NAD(P)H dehydrogenase (quinone) activity
PA257_4577	COG2957	Belongs to the agmatine deiminase family
PA257_4580	COG2957	Belongs to the agmatine deiminase family
PA257_4582	COG0583	DNA-binding transcription factor activity
PA257_4584	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PA257_4589	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PA257_4591	COG0318	PFAM AMP-dependent synthetase and ligase
PA257_4592	COG0367	asparagine synthase
PA257_4594	COG2211	Major facilitator Superfamily
PA257_4604	COG1335	isochorismatase
PA257_4605	COG0583	DNA-binding transcription factor activity
PA257_4607	COG0791	NLP P60 protein
PA257_4608	COG0791	NLP P60 protein
PA257_4610	COG3829	transcription factor binding
PA257_4613	COG2818	Glycosylase
PA257_4618	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PA257_4619	COG1960	acyl-CoA dehydrogenase activity
PA257_4621	COG0625	glutathione transferase activity
PA257_4626	COG5001	Diguanylate cyclase
PA257_4626	COG3447	MASE1 domain protein
PA257_4626	COG5002	protein histidine kinase activity
PA257_4628	COG0745	RESPONSE REGULATOR receiver
PA257_4630	COG4459	periplasmic nitrate reductase
PA257_4631	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
PA257_4631	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PA257_4632	COG3062	negative regulation of establishment of protein localization
PA257_4634	COG3043	anaerobic respiration
PA257_4635	COG3005	denitrification pathway
PA257_4636	COG2951	lytic endotransglycosylase activity
PA257_4637	COG0861	Integral membrane protein TerC family
PA257_4638	COG0753	catalase activity
PA257_4642	COG2977	Belongs to the P-Pant transferase superfamily
PA257_4643	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PA257_4646	COG2226	methyltransferase
PA257_4649	COG2205	protein histidine kinase activity
PA257_4650	COG0745	RESPONSE REGULATOR receiver
PA257_4652	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PA257_4652	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PA257_4653	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PA257_4654	COG1943	Transposase
PA257_4661	COG0531	amino acid
PA257_4666	COG0560	Phosphoserine phosphatase
PA257_4668	COG0583	DNA-binding transcription factor activity
PA257_4669	COG3257	ureidoglycine aminohydrolase activity
PA257_4673	COG2197	response regulator
PA257_4681	COG0583	DNA-binding transcription factor activity
PA257_4682	COG0667	Aldo Keto reductase
PA257_4689	COG0242	peptide deformylase activity
PA257_4691	COG2199	diguanylate cyclase activity
PA257_4692	COG2885	chlorophyll binding
PA257_4701	COG4628	conserved protein (DUF2132)
PA257_4702	COG2133	pyrroloquinoline quinone binding
PA257_4705	COG2207	Transcriptional regulator
PA257_4706	COG0477	Major facilitator Superfamily
PA257_4709	COG2882	bacterial-type flagellum organization
PA257_4715	COG2204	response regulator
PA257_4716	COG4191	Histidine kinase
PA257_4717	COG2204	response regulator
PA257_4720	COG1516	flagellar protein fliS
PA257_4721	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PA257_4723	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PA257_4724	COG1216	Glycosyl transferase, family 2
PA257_4724	COG0438	transferase activity, transferring glycosyl groups
PA257_4729	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_4730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PA257_4734	COG1256	bacterial-type flagellum assembly
PA257_4738	COG4786	Flagellar basal body rod
PA257_4739	COG4787	bacterial-type flagellum-dependent cell motility
PA257_4740	COG1749	Flagellar hook protein flgE
PA257_4741	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PA257_4742	COG1558	bacterial-type flagellum-dependent cell motility
PA257_4743	COG1815	bacterial-type flagellum-dependent cell motility
PA257_4753	COG0326	Molecular chaperone. Has ATPase activity
PA257_4756	COG3189	MarR family transcriptional regulator
PA257_4760	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PA257_4763	COG2212	antiporter activity
PA257_4765	COG0651	ATP synthesis coupled electron transport
PA257_4766	COG1006	Multisubunit Na H antiporter MnhC subunit
PA257_4767	COG2111	Na H antiporter
PA257_4767	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PA257_4768	COG3133	Outer membrane lipoprotein
PA257_4770	COG1929	Belongs to the glycerate kinase type-1 family
PA257_4771	COG2610	gluconate transmembrane transporter activity
PA257_4772	COG3835	regulator
PA257_4774	COG2885	chlorophyll binding
PA257_4777	COG1199	ATP-dependent helicase activity
PA257_4785	COG2860	membrane
PA257_4788	COG0653	protein targeting
PA257_4789	COG0625	glutathione transferase activity
PA257_4794	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PA257_4795	COG1012	belongs to the aldehyde dehydrogenase family
PA257_4800	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_4801	COG1960	acyl-CoA dehydrogenase activity
PA257_4802	COG1024	Enoyl-CoA hydratase
PA257_4803	COG1960	acyl-CoA dehydrogenase activity
PA257_4805	COG2814	Major facilitator Superfamily
PA257_4806	COG2030	dehydratase
PA257_4808	COG0183	Belongs to the thiolase family
PA257_4814	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PA257_4815	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PA257_4818	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PA257_4820	COG0425	Belongs to the sulfur carrier protein TusA family
PA257_4821	COG4783	chaperone-mediated protein folding
PA257_4823	COG0583	DNA-binding transcription factor activity
PA257_4831	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PA257_4832	COG3188	usher protein
PA257_4840	COG2801	Transposase and inactivated derivatives
PA257_4841	COG4372	Transposase
PA257_4847	COG0475	glutathione-regulated potassium exporter activity
PA257_4847	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PA257_4849	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_4850	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_4852	COG0235	Class ii aldolase
PA257_4854	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PA257_4855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PA257_4857	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PA257_4859	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PA257_4862	COG0602	queuosine metabolic process
PA257_4863	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PA257_4869	COG0824	Thioesterase
PA257_4875	COG0783	Belongs to the Dps family
PA257_4885	COG3118	belongs to the thioredoxin family
PA257_4892	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PA257_4895	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PA257_4903	COG3122	Protein conserved in bacteria
PA257_4905	COG3956	TIGRFAM MazG family protein
PA257_4906	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PA257_4912	COG5002	protein histidine kinase activity
PA257_4912	COG2205	protein histidine kinase activity
PA257_4912	COG0784	Response regulator, receiver
PA257_4913	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PA257_4923	COG3038	cytochrome b561
PA257_4927	COG4807	Protein conserved in bacteria
PA257_4929	COG2239	Acts as a magnesium transporter
PA257_4943	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PA257_4956	COG4215	(ABC) transporter
PA257_4962	COG2301	Belongs to the HpcH HpaI aldolase family
PA257_4964	COG2079	MmgE PrpD family protein
PA257_4966	COG1960	acyl-CoA dehydrogenase activity
PA257_4967	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PA257_4968	COG0583	DNA-binding transcription factor activity
PA257_4969	COG0583	DNA-binding transcription factor activity
PA257_4974	COG3283	Transcriptional regulator of aromatic amino acids metabolism
PA257_4981	COG1113	amino acid transport
PA257_4986	COG3321	synthase
PA257_4986	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_4986	COG0604	alcohol dehydrogenase
PA257_4988	COG5001	Diguanylate cyclase
PA257_4988	COG5002	protein histidine kinase activity
PA257_4989	COG1132	(ABC) transporter
PA257_4992	COG0271	Belongs to the BolA IbaG family
PA257_5000	COG0492	ferredoxin-NADP+ reductase activity
PA257_5001	COG0450	alkyl hydroperoxide reductase
PA257_5009	COG1307	EDD domain protein, DegV family
PA257_5011	COG1309	transcriptional regulator
PA257_5012	COG0386	Belongs to the glutathione peroxidase family
PA257_5017	COG0204	Acyl-transferase
PA257_5018	COG2885	chlorophyll binding
PA257_5019	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PA257_5022	COG2267	carboxylic ester hydrolase activity
PA257_5041	COG4695	Portal protein
PA257_5049	COG3179	chitinase
PA257_5051	COG3646	Phage regulatory protein
PA257_5054	COG0305	Participates in initiation and elongation during chromosome replication
PA257_5078	COG0582	viral genome integration into host DNA
PA257_5093	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PA257_5096	COG0546	phosphoglycolate phosphatase activity
PA257_5099	COG3023	N-Acetylmuramoyl-L-alanine amidase
PA257_5102	COG0656	L-ascorbic acid biosynthetic process
PA257_5107	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PA257_5109	COG1802	Transcriptional regulator
PA257_5111	COG0372	Belongs to the citrate synthase family
PA257_5114	COG2079	MmgE PrpD family protein
PA257_5117	COG1113	amino acid transport
PA257_5118	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PA257_5122	COG2076	Multidrug Resistance protein
PA257_5124	COG0583	DNA-binding transcription factor activity
PA257_5125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PA257_5127	COG4206	TonB-dependent receptor
PA257_5130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PA257_5143	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PA257_5159	COG3180	Ammonia monooxygenase
PA257_5161	COG2720	vancomycin resistance protein
PA257_5164	COG1960	acyl-CoA dehydrogenase activity
PA257_5165	COG1024	Enoyl-CoA hydratase
PA257_5169	COG2910	NAD(P)H-binding
PA257_5170	COG2015	COG2015, Alkyl sulfatase and related hydrolases
PA257_5184	COG0582	viral genome integration into host DNA
PA257_5187	COG1192	Involved in chromosome partitioning
PA257_5194	COG0629	single-stranded DNA binding
PA257_5195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PA257_5228	COG2003	Belongs to the UPF0758 family
PA257_5254	COG3316	Transposase and inactivated derivatives
PA257_5257	COG0789	Transcriptional regulator
PA257_5259	COG2608	mercury ion transmembrane transporter activity
PA257_5260	COG2608	mercury ion transmembrane transporter activity
PA257_5261	COG0789	Transcriptional regulator
PA257_5263	COG1120	ATPase activity
PA257_5266	COG3586	endonuclease activity
PA257_5268	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PA257_5270	COG0583	DNA-binding transcription factor activity
PA257_5272	COG0464	growth
PA257_5276	COG4974	Belongs to the 'phage' integrase family
PA257_5278	COG4128	Pfam Zonular occludens toxin
PA257_5291	COG0583	DNA-binding transcription factor activity
PA257_5295	COG0463	Glycosyl transferase, family 2
PA257_5297	COG0154	amidase activity
PA257_5298	COG0477	Major facilitator Superfamily
PA257_5301	COG0583	DNA-binding transcription factor activity
PA257_5303	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PA257_5310	COG2831	hemolysin activation secretion protein
PA257_5342	COG0420	3'-5' exonuclease activity
PA257_5344	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PA257_5345	COG1074	ATP-dependent DNA helicase activity
PA257_5346	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PA257_5347	COG0095	Lipoate-protein ligase
PA257_5348	COG0697	spore germination
PA257_5351	COG0840	transmembrane signaling receptor activity
PA257_5353	COG0306	phosphate transporter
PA257_5357	COG4566	intracellular signal transduction
PA257_5365	COG4964	Belongs to the GSP D family
PA257_5369	COG0433	COG0433 Predicted ATPase
PA257_5378	COG0788	formyltetrahydrofolate deformylase activity
PA257_5380	COG2925	Exonuclease
PA257_5386	COG0714	Associated with various cellular activities
PA257_5392	COG0589	response to stress
PA257_5394	COG1024	Enoyl-CoA hydratase
PA257_5396	COG3706	GGDEF domain
PA257_5400	COG0693	protein deglycase activity
PA257_5403	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PA257_5406	COG0154	amidase activity
PA257_5408	COG1473	amidohydrolase
PA257_5411	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PA257_5412	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PA257_5412	COG0426	domain, Protein
PA257_5416	COG0589	response to stress
PA257_5419	COG2814	Major facilitator Superfamily
PA257_5420	COG1902	pentaerythritol trinitrate reductase activity
PA257_5423	COG1918	ferrous iron import across plasma membrane
PA257_5426	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PA257_5434	COG1704	LemA family
PA257_5439	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PA257_5440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PA257_5443	COG3642	lipopolysaccharide core region biosynthetic process
PA257_5445	COG2205	protein histidine kinase activity
PA257_5446	COG0745	RESPONSE REGULATOR receiver
PA257_5453	COG3030	protein affecting phage T7 exclusion by the F plasmid
PA257_5455	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_5460	COG0668	transmembrane transport
PA257_5465	COG2096	Adenosyltransferase
PA257_5466	COG0494	nUDIX hydrolase
PA257_5471	COG0739	heme binding
PA257_5471	COG0741	lytic transglycosylase activity
PA257_5471	COG1196	nuclear chromosome segregation
PA257_5480	COG0772	Belongs to the SEDS family
PA257_5483	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PA257_5490	COG3107	peptidoglycan biosynthetic process
PA257_5493	COG2823	Periplasmic or secreted lipoprotein
PA257_5494	COG2969	positive regulation of protein catabolic process
PA257_5495	COG0625	glutathione transferase activity
PA257_5496	COG2857	Cytochrome c1
PA257_5497	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PA257_5498	COG0723	plastoquinol--plastocyanin reductase activity
PA257_5501	COG0667	Aldo Keto reductase
PA257_5502	COG1960	acyl-CoA dehydrogenase activity
PA257_5505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PA257_5507	COG2945	thiolester hydrolase activity
PA257_5511	COG2951	lytic endotransglycosylase activity
PA257_5513	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PA257_5522	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PA257_5523	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PA257_5524	COG1127	ABC transporter
PA257_5526	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PA257_5529	COG1137	ATPase activity
PA257_5540	COG0312	modulator of DNA gyrase
PA257_5542	COG0312	modulator of DNA gyrase
PA257_5543	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PA257_5545	COG1530	ribonuclease E activity
PA257_5548	COG1792	Involved in formation and maintenance of cell shape
PA257_5549	COG1077	Cell shape determining protein MreB Mrl
PA257_5554	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PA257_5555	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PA257_5556	COG4676	Protein conserved in bacteria
PA257_5557	COG5445	Predicted secreted protein (DUF2300)
PA257_5560	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
PA257_5561	COG4676	Protein conserved in bacteria
PA257_5562	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PA257_5565	COG0747	negative chemotaxis
PA257_5566	COG0747	negative chemotaxis
PA257_5570	COG0747	negative chemotaxis
PA257_5573	COG0747	negative chemotaxis
PA257_5574	COG0601	transmembrane transport
PA257_5575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PA257_5576	COG0444	Belongs to the ABC transporter superfamily
PA257_5577	COG4608	Belongs to the ABC transporter superfamily
PA257_5579	COG1522	sequence-specific DNA binding
PA257_5580	COG1984	allophanate hydrolase subunit 2
PA257_5585	COG4774	siderophore transport
PA257_5588	COG2194	sulfuric ester hydrolase activity
PA257_5590	COG0019	diaminopimelate decarboxylase activity
PA257_5612	COG1252	NADH dehydrogenase
PA257_5613	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PA257_5614	COG2831	hemolysin activation secretion protein
PA257_5617	COG1192	Involved in chromosome partitioning
PA257_5625	COG0305	Participates in initiation and elongation during chromosome replication
PA257_5642	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PA257_5645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PA257_5650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PA257_5688	COG1074	ATP-dependent DNA helicase activity
PA257_5710	COG3609	addiction module antidote protein, CC2985 family
PA257_5713	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PA257_5732	COG4968	Prepilin-type N-terminal cleavage methylation domain
PA257_5734	COG1047	Peptidyl-prolyl cis-trans
PA257_5737	COG0196	riboflavin kinase activity
PA257_5740	COG3045	CreA protein
PA257_5745	COG0142	geranyltranstransferase activity
PA257_5748	COG0545	Peptidyl-prolyl cis-trans isomerase
PA257_5752	COG1067	ATP-dependent peptidase activity
PA257_5757	COG4650	regulator
PA257_5762	COG1690	Belongs to the RtcB family
PA257_5763	COG3541	Predicted nucleotidyltransferase
PA257_5767	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PA257_5772	COG0577	efflux transmembrane transporter activity
PA257_5772	COG1136	(ABC) transporter
PA257_5773	COG0577	efflux transmembrane transporter activity
PA257_5773	COG1136	(ABC) transporter
PA257_5774	COG0488	(ABC) transporter
PA257_5778	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PA257_5779	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PA257_5784	COG0523	cobalamin synthesis protein
PA257_5786	COG2879	small protein
PA257_5787	COG1966	Carbon starvation protein
PA257_5801	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PA257_5801	COG3608	succinylglutamate desuccinylase aspartoacylase
PA257_5802	COG2010	Cytochrome c
PA257_5810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PA257_5812	COG0833	amino acid
PA257_5813	COG2119	membrane
PA257_5816	COG0501	Belongs to the peptidase M48B family
PA257_5817	COG0840	transmembrane signaling receptor activity
PA257_5818	COG2135	peptidase activity
PA257_5819	COG1285	pathogenesis
PA257_5842	COG1090	epimerase
PA257_5843	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PA257_5845	COG0789	Transcriptional regulator
PA257_5846	COG0415	Belongs to the DNA photolyase family
PA257_5849	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PA257_5860	COG0012	GTP binding
PA257_5862	COG4974	Belongs to the 'phage' integrase family
PA257_5864	COG4128	Pfam Zonular occludens toxin
PA257_5879	COG0288	reversible hydration of carbon dioxide
PA257_5881	COG0456	acetyltransferase
PA257_5890	COG1840	ABC-type Fe3 transport system, periplasmic component
PA257_5891	COG1178	ABC-type Fe3 transport system permease component
PA257_5892	COG3008	intermembrane lipid transfer
PA257_5893	COG2995	paraquat-inducible protein a
PA257_5894	COG2995	paraquat-inducible protein a
PA257_5903	COG1183	phosphatidylcholine synthase activity
PA257_5906	COG0028	Belongs to the TPP enzyme family
PA257_5909	COG3098	single-species biofilm formation
PA257_5911	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PA257_5919	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PA257_5920	COG4558	Periplasmic binding protein
PA257_5921	COG3720	iron ion transport
PA257_5923	COG4771	TonB-dependent receptor
PA257_5928	COG0436	Aminotransferase
PA257_5930	COG2321	neutral zinc metallopeptidase
PA257_5932	COG2252	PERMEase
PA257_5936	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PA257_5939	COG4191	Histidine kinase
PA257_5960	COG0195	Participates in both transcription termination and antitermination
PA257_5967	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PA257_5968	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PA257_5981	COG0497	DNA recombination
PA257_5988	COG2186	Transcriptional regulator
PA257_5989	COG1620	l-lactate permease
PA257_5995	COG0745	RESPONSE REGULATOR receiver
PA257_5999	COG0697	spore germination
PA257_6003	COG0697	spore germination
PA257_6004	COG1522	sequence-specific DNA binding
PA257_6032	COG4373	Mu-like prophage FluMu protein gp28
PA257_6058	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_6062	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PA257_6068	COG0509	glycine decarboxylation via glycine cleavage system
PA257_6076	COG0531	amino acid
PA257_6079	COG3276	selenocysteine insertion sequence binding
PA257_6082	COG2864	formate dehydrogenase
PA257_6083	COG0437	4 iron, 4 sulfur cluster binding
PA257_6084	COG0243	molybdopterin cofactor binding
PA257_6084	COG3383	formate dehydrogenase (NAD+) activity
PA257_6085	COG0243	molybdopterin cofactor binding
PA257_6085	COG3383	formate dehydrogenase (NAD+) activity
PA257_6086	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PA257_6087	COG1902	pentaerythritol trinitrate reductase activity
PA257_6087	COG0446	pyridine nucleotide-disulphide oxidoreductase
PA257_6092	COG0463	Glycosyl transferase, family 2
PA257_6094	COG0534	Mate efflux family protein
PA257_6096	COG1283	sodium-dependent phosphate transmembrane transporter activity
PA257_6101	COG2162	N-hydroxyarylamine O-acetyltransferase activity
PA257_6106	COG4221	oxidoreductase activity
PA257_6107	COG1272	protein, Hemolysin III
PA257_6115	COG0023	Translation Initiation Factor
PA257_6133	COG2095	MarC family integral membrane protein
PA257_6135	COG0683	leucine binding
PA257_6136	COG0559	Belongs to the binding-protein-dependent transport system permease family
PA257_6138	COG0411	ABC transporter
PA257_6147	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PA257_6151	COG0443	Heat shock 70 kDa protein
PA257_6156	COG0789	Transcriptional regulator
PA257_6157	COG2982	Protein involved in outer membrane biogenesis
PA257_6158	COG2193	ferroxidase activity
PA257_6160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PA257_6161	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
PA257_6173	COG3712	iron ion homeostasis
PA257_6174	COG1595	DNA-templated transcription, initiation
PA257_6178	COG2814	Major facilitator Superfamily
PA257_6180	COG0583	DNA-binding transcription factor activity
PA257_6186	COG4221	oxidoreductase activity
PA257_6187	COG2423	ornithine cyclodeaminase activity
PA257_6188	COG0410	ABC transporter
PA257_6191	COG0559	Belongs to the binding-protein-dependent transport system permease family
PA257_6193	COG0583	DNA-binding transcription factor activity
PA257_6196	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PA257_6204	COG0668	transmembrane transport
PA257_6209	COG5001	Diguanylate cyclase
PA257_6209	COG3300	MHYT domain
PA257_6212	COG0305	Participates in initiation and elongation during chromosome replication
PA257_6218	COG0557	exoribonuclease II activity
PA257_6224	COG0330	HflC and HflK could
PA257_6225	COG0330	HflC and HflK could
PA257_6226	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PA257_6230	COG0860	N-Acetylmuramoyl-L-alanine amidase
PA257_6231	COG0802	atpase or kinase
PA257_6232	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PA257_6232	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PA257_6242	COG3300	MHYT domain
PA257_6242	COG5001	Diguanylate cyclase
PA257_6243	COG3830	Belongs to the UPF0237 family
PA257_6243	COG0560	Phosphoserine phosphatase
PA257_6245	COG1988	membrane-bound metal-dependent
PA257_6248	COG3577	Aspartyl protease
PA257_6251	COG3150	esterase
PA257_6252	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PA257_6254	COG0494	nUDIX hydrolase
PA257_6259	COG1538	Outer membrane efflux protein
PA257_6260	COG2249	NAD(P)H dehydrogenase (quinone) activity
PA257_6263	COG0045	succinate-CoA ligase (ADP-forming) activity
PA257_6264	COG1960	acyl-CoA dehydrogenase activity
PA257_6265	COG1024	Enoyl-CoA hydratase
PA257_6267	COG0833	amino acid
PA257_6274	COG0446	pyridine nucleotide-disulphide oxidoreductase
PA257_6274	COG1902	pentaerythritol trinitrate reductase activity
PA257_6276	COG1519	Transferase
PA257_6277	COG0583	DNA-binding transcription factor activity
PA257_6280	COG0667	Aldo Keto reductase
PA257_6282	COG1960	acyl-CoA dehydrogenase activity
PA257_6283	COG1960	acyl-CoA dehydrogenase activity
PA257_6288	COG1215	transferase activity, transferring glycosyl groups
PA257_6292	COG0438	transferase activity, transferring glycosyl groups
PA257_6293	COG2192	nodulation
PA257_6298	COG0438	transferase activity, transferring glycosyl groups
PA257_6299	COG0859	PFAM glycosyl transferase family 9
PA257_6300	COG0859	PFAM glycosyl transferase family 9
PA257_6309	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PA257_6310	COG1960	acyl-CoA dehydrogenase activity
PA257_6313	COG3264	Mechanosensitive ion channel
PA257_6313	COG1196	nuclear chromosome segregation
PA257_6315	COG0730	response to heat
PA257_6319	COG1192	Involved in chromosome partitioning
PA257_6320	COG0583	DNA-binding transcription factor activity
PA257_6321	COG2814	Major facilitator Superfamily
PA257_6326	COG0493	'glutamate synthase
PA257_6327	COG0069	glutamate synthase activity
PA257_6327	COG0070	glutamate synthase
PA257_6327	COG0067	glutamate synthase
PA257_6337	COG0281	malic enzyme
PA257_6341	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PA257_6364	COG0840	transmembrane signaling receptor activity
PA257_6366	COG1126	abc transporter atp-binding protein
PA257_6367	COG0765	amino acid transport
PA257_6373	COG1051	belongs to the nudix hydrolase family
PA257_6374	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PA257_6375	COG0251	oxidation-reduction process
PA257_6380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PA257_6381	COG3501	Rhs element vgr protein
PA257_6384	COG2986	histidine ammonia-lyase
PA257_6385	COG4175	Glycine betaine
PA257_6386	COG4176	ABC-type proline glycine betaine transport system permease component
PA257_6390	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PA257_6397	COG0402	S-adenosylhomocysteine deaminase activity
PA257_6407	COG0789	Transcriptional regulator
PA257_6413	COG0668	transmembrane transport
PA257_6416	COG3852	Histidine kinase
PA257_6420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PA257_6427	COG4942	peptidase
PA257_6428	COG0793	Belongs to the peptidase S41A family
PA257_6429	COG2861	carbohydrate metabolic process
PA257_6441	COG0579	oxidoreductase
PA257_6443	COG1194	a g-specific adenine glycosylase
PA257_6445	COG0673	inositol 2-dehydrogenase activity
PA257_6447	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_6454	COG1846	Transcriptional regulator
PA257_6456	COG1566	PFAM secretion protein HlyD family protein
PA257_6457	COG2814	Major facilitator Superfamily
PA257_6462	COG4695	Portal protein
PA257_6509	COG0582	viral genome integration into host DNA
PA257_6512	COG1088	dTDP-glucose 4,6-dehydratase activity
PA257_6513	COG1091	dTDP-4-dehydrorhamnose reductase activity
PA257_6527	COG0494	nUDIX hydrolase
PA257_6528	COG1011	Hydrolase
PA257_6529	COG1652	LysM domain
PA257_6531	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PA257_6535	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PA257_6537	COG0824	Thioesterase
PA257_6538	COG1454	alcohol dehydrogenase
PA257_6539	COG1960	acyl-CoA dehydrogenase activity
PA257_6540	COG1250	3-hydroxyacyl-CoA dehydrogenase
PA257_6540	COG1024	Enoyl-CoA hydratase
PA257_6542	COG0778	Nitroreductase
PA257_6547	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PA257_6548	COG0189	ligase activity
PA257_6548	COG4067	protein conserved in archaea
PA257_6551	COG2205	protein histidine kinase activity
PA257_6552	COG0745	RESPONSE REGULATOR receiver
PA257_6553	COG2183	response to ionizing radiation
PA257_6559	COG0306	phosphate transporter
PA257_6560	COG1392	Phosphate transport regulator
PA257_6561	COG3025	triphosphatase activity
PA257_6568	COG1178	ABC-type Fe3 transport system permease component
PA257_6570	COG0583	DNA-binding transcription factor activity
PA257_6573	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PA257_6575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PA257_6576	COG0006	proline dipeptidase activity
PA257_6580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PA257_6583	COG0842	Transport permease protein
PA257_6584	COG1129	ABC transporter
PA257_6584	COG0842	Transport permease protein
PA257_6585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PA257_6588	COG2271	Major facilitator Superfamily
PA257_6591	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PA257_6591	COG2755	lipolytic protein G-D-S-L family
PA257_6595	COG0248	Ppx GppA phosphatase
PA257_6598	COG0586	Pfam SNARE associated Golgi protein
PA257_6599	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PA257_6600	COG2050	protein possibly involved in aromatic compounds catabolism
PA257_6602	COG0672	)-iron permease
PA257_6603	COG1280	lysine exporter protein (LysE YggA)
PA257_6604	COG0861	Integral membrane protein TerC family
PA257_6606	COG0488	(ABC) transporter
PA257_6617	COG3275	phosphorelay sensor kinase activity
PA257_6621	COG3501	Rhs element vgr protein
PA257_6623	COG0598	Magnesium transport protein CorA
PA257_6629	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PA257_6643	COG0432	Pfam Uncharacterised protein family UPF0047
PA257_6644	COG0004	ammonium transporteR
PA257_6645	COG0347	Belongs to the P(II) protein family
PA257_6647	COG0606	chelatase, subunit chli
PA257_6668	COG0210	DNA helicase
PA257_6670	COG1074	ATP-dependent DNA helicase activity
PA257_6674	COG0606	chelatase, subunit chli
PA257_6675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PA257_6677	COG0583	DNA-binding transcription factor activity
PA257_6679	COG0210	DNA helicase
PA257_6680	COG0028	Belongs to the TPP enzyme family
PA257_6682	COG0427	acetyl-CoA hydrolase
PA257_6684	COG1917	Cupin 2, conserved barrel domain protein
PA257_6684	COG1396	sequence-specific DNA binding
PA257_6686	COG0251	oxidation-reduction process
PA257_6691	COG1522	sequence-specific DNA binding
PA257_6692	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PA257_6693	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PA257_6694	COG2814	Major facilitator Superfamily
PA257_6695	COG1012	belongs to the aldehyde dehydrogenase family
PA257_6702	COG0747	negative chemotaxis
PA257_6705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PA257_6713	COG3245	cytochrome
PA257_6717	COG0708	Exodeoxyribonuclease III
PA257_6720	COG1561	YicC-like family, N-terminal region
PA257_6723	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PA257_6730	COG0583	DNA-binding transcription factor activity
PA257_6731	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PA257_6740	COG3193	protein, possibly involved in utilization of glycolate and propanediol
PA257_6741	COG0247	lactate metabolic process
PA257_6742	COG0277	FAD linked oxidase domain protein
PA257_6743	COG0277	FAD linked oxidase domain protein
PA257_6744	COG2186	Transcriptional regulator
PA257_6750	COG1253	flavin adenine dinucleotide binding
PA257_6751	COG0739	heme binding
PA257_6755	COG0573	inorganic phosphate transmembrane transporter activity
PA257_6764	COG0477	Major facilitator Superfamily
PA257_6765	COG1607	acyl-coa hydrolase
PA257_6770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PA257_6771	COG4175	Glycine betaine
PA257_6772	COG4176	ABC-type proline glycine betaine transport system permease component
PA257_6774	COG1760	l-serine dehydratase
PA257_6777	COG0583	DNA-binding transcription factor activity
PA257_6782	COG3246	L-lysine catabolic process to acetate
PA257_6793	COG0446	pyridine nucleotide-disulphide oxidoreductase
PA257_6793	COG1902	pentaerythritol trinitrate reductase activity
PA257_6794	COG0247	lactate metabolic process
PA257_6794	COG2181	nitrate reductase activity
PA257_6795	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PA257_6798	COG3655	Transcriptional regulator
PA257_6806	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PA257_6806	COG1017	nitric oxide dioxygenase activity
PA257_6824	COG0583	DNA-binding transcription factor activity
PA257_6827	COG2391	methyltransferase activity
PA257_6832	COG5016	pyruvate
PA257_6832	COG0511	ligase activity, forming carbon-carbon bonds
PA257_6833	COG0439	Biotin carboxylase
PA257_6834	COG0583	DNA-binding transcription factor activity
PA257_6837	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PA257_6842	COG0210	DNA helicase
PA257_6844	COG0427	acetyl-CoA hydrolase
PA257_6847	COG0438	transferase activity, transferring glycosyl groups
PA257_6857	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PA257_6858	COG2755	lipolytic protein G-D-S-L family
PA257_6858	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PA257_6866	COG0679	Auxin Efflux Carrier
PA257_6868	COG2851	Citrate transporter
PA257_6869	COG0861	Integral membrane protein TerC family
PA257_6870	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PA257_6871	COG1690	Belongs to the RtcB family
PA257_6880	COG0700	Nucleoside recognition
PA257_6881	COG1301	dicarboxylic acid transport
PA257_6885	COG5002	protein histidine kinase activity
PA257_6886	COG3023	N-Acetylmuramoyl-L-alanine amidase
PA257_6887	COG2095	MarC family integral membrane protein
PA257_6888	COG3706	GGDEF domain
PA257_6888	COG0745	RESPONSE REGULATOR receiver
PA257_6892	COG3245	cytochrome
PA257_6899	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PA257_6900	COG0735	belongs to the Fur family
PA257_6902	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PA257_6905	COG2011	ABC-type metal ion transport system permease component
PA257_6911	COG0531	amino acid
PA257_6913	COG4191	Histidine kinase
PA257_6920	COG4651	solute:proton antiporter activity
PA257_6920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PA257_6921	COG1607	acyl-coa hydrolase
PA257_6923	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_6924	COG0174	glutamine synthetase
PA257_6925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PA257_6926	COG1028	Short-chain dehydrogenase reductase Sdr
PA257_6933	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PA257_6933	COG4651	solute:proton antiporter activity
PA257_6934	COG0477	Major facilitator Superfamily
PA257_6937	COG0523	cobalamin synthesis protein
PA257_6941	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PA257_6946	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PA257_6951	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PA257_6952	COG0560	Phosphoserine phosphatase
PA257_6955	COG1349	DNA-binding transcription factor activity
PA257_6967	COG1475	DNA binding
PA257_6968	COG1192	Involved in chromosome partitioning