locus-tag	class	description
Y89_0009	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Y89_0013	COG2010	Cytochrome c
Y89_0016	COG2818	Glycosylase
Y89_0019	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Y89_0022	COG0569	domain protein
Y89_0026	COG1652	LysM domain
Y89_0027	COG0758	DNA mediated transformation
Y89_0033	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Y89_0037	COG3119	arylsulfatase activity
Y89_0038	COG0583	DNA-binding transcription factor activity
Y89_0045	COG3360	Dodecin
Y89_0048	COG3210	domain, Protein
Y89_0048	COG3210	domain, Protein
Y89_0053	COG3174	membrane
Y89_0062	COG0367	asparagine synthase
Y89_0066	COG0583	DNA-binding transcription factor activity
Y89_0069	COG1764	response to oxidative stress
Y89_0076	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Y89_0077	COG0339	signal peptide processing
Y89_0078	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
Y89_0081	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Y89_0084	COG2815	serine threonine protein kinase
Y89_0084	COG0515	serine threonine protein kinase
Y89_0085	COG0631	protein serine/threonine phosphatase activity
Y89_0088	COG1360	Flagellar Motor Protein
Y89_0101	COG3501	Rhs element vgr protein
Y89_0106	COG3501	Rhs element vgr protein
Y89_0114	COG0659	secondary active sulfate transmembrane transporter activity
Y89_0116	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Y89_0117	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Y89_0118	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Y89_0126	COG2153	protein acetylation
Y89_0127	COG1733	regulation of RNA biosynthetic process
Y89_0134	COG0583	DNA-binding transcription factor activity
Y89_0139	COG2824	Alkylphosphonate utilization operon protein PhnA
Y89_0140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Y89_0147	COG0402	S-adenosylhomocysteine deaminase activity
Y89_0149	COG1129	ABC transporter
Y89_0165	COG0583	DNA-binding transcription factor activity
Y89_0166	COG3485	protocatechuate 3,4-dioxygenase
Y89_0167	COG3485	protocatechuate 3,4-dioxygenase
Y89_0168	COG1414	Transcriptional regulator
Y89_0171	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y89_0172	COG0583	DNA-binding transcription factor activity
Y89_0178	COG2233	PERMEase
Y89_0179	COG1309	transcriptional regulator
Y89_0181	COG3706	GGDEF domain
Y89_0181	COG0745	RESPONSE REGULATOR receiver
Y89_0186	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Y89_0189	COG0835	chemotaxis
Y89_0190	COG2198	Histidine kinase
Y89_0190	COG0643	Histidine kinase
Y89_0191	COG0745	RESPONSE REGULATOR receiver
Y89_0193	COG0583	DNA-binding transcription factor activity
Y89_0194	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_0196	COG1116	anion transmembrane transporter activity
Y89_0197	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Y89_0198	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Y89_0206	COG2175	clavaminate synthase activity
Y89_0207	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Y89_0208	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Y89_0209	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Y89_0221	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Y89_0226	COG1012	belongs to the aldehyde dehydrogenase family
Y89_0227	COG1113	amino acid transport
Y89_0230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Y89_0231	COG0235	Class ii aldolase
Y89_0232	COG1396	sequence-specific DNA binding
Y89_0233	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Y89_0234	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Y89_0236	COG0477	Major facilitator Superfamily
Y89_0238	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Y89_0239	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Y89_0240	COG0583	DNA-binding transcription factor activity
Y89_0244	COG0673	inositol 2-dehydrogenase activity
Y89_0248	COG2271	Major facilitator Superfamily
Y89_0250	COG1309	transcriptional regulator
Y89_0251	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Y89_0253	COG0477	Major facilitator Superfamily
Y89_0257	COG2239	Acts as a magnesium transporter
Y89_0260	COG1846	Transcriptional regulator
Y89_0270	COG3501	Rhs element vgr protein
Y89_0282	COG0582	viral genome integration into host DNA
Y89_0285	COG0745	RESPONSE REGULATOR receiver
Y89_0287	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Y89_0290	COG0583	DNA-binding transcription factor activity
Y89_0291	COG2807	transmembrane transport
Y89_0295	COG0501	Belongs to the peptidase M48B family
Y89_0299	COG4208	sulfate ABC transporter
Y89_0301	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Y89_0308	COG3706	GGDEF domain
Y89_0313	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Y89_0314	COG0174	glutamine synthetase
Y89_0315	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Y89_0316	COG0174	glutamine synthetase
Y89_0320	COG3842	ATPase activity
Y89_0321	COG1176	ABC-type spermidine putrescine transport system, permease component I
Y89_0322	COG1177	transmembrane transport
Y89_0336	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Y89_0337	COG0277	FAD linked oxidase domain protein
Y89_0338	COG0179	Fumarylacetoacetate (FAA) hydrolase
Y89_0340	COG3111	PFAM Bacterial OB fold (BOF) protein
Y89_0342	COG0531	amino acid
Y89_0343	COG2182	Extracellular solute-binding protein
Y89_0344	COG1177	transmembrane transport
Y89_0345	COG1176	ABC-type spermidine putrescine transport system, permease component I
Y89_0346	COG3842	ATPase activity
Y89_0347	COG3204	pilus organization
Y89_0348	COG2234	aminopeptidase activity
Y89_0351	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Y89_0353	COG0702	epimerase
Y89_0359	COG3706	GGDEF domain
Y89_0361	COG0730	response to heat
Y89_0368	COG0584	glycerophosphoryl diester phosphodiesterase
Y89_0372	COG0622	Phosphoesterase
Y89_0373	COG2233	PERMEase
Y89_0376	COG0693	protein deglycase activity
Y89_0383	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Y89_0385	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Y89_0390	COG0429	hydrolase of the alpha beta-hydrolase fold
Y89_0392	COG0742	ribosomal rna small subunit methyltransferase
Y89_0393	COG0612	Peptidase, M16
Y89_0394	COG0612	Peptidase, M16
Y89_0395	COG0552	protein localization to endoplasmic reticulum
Y89_0396	COG2884	Cell division ATP-binding protein ftsE
Y89_0397	COG2177	Part of the ABC transporter FtsEX involved in
Y89_0401	COG2363	Small membrane protein
Y89_0408	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Y89_0411	COG2813	Specifically methylates the guanine in position
Y89_0411	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Y89_0413	COG1160	GTP binding
Y89_0414	COG1872	DUF167
Y89_0423	COG0626	cystathionine gamma-synthase activity
Y89_0442	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Y89_0445	COG3038	cytochrome b561
Y89_0451	COG0513	Belongs to the DEAD box helicase family
Y89_0453	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Y89_0459	COG1309	transcriptional regulator
Y89_0460	COG0402	S-adenosylhomocysteine deaminase activity
Y89_0461	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Y89_0465	COG1953	Uracil, thiamine, allantoin
Y89_0468	COG1960	acyl-CoA dehydrogenase activity
Y89_0469	COG0583	DNA-binding transcription factor activity
Y89_0471	COG0306	phosphate transporter
Y89_0473	COG0330	HflC and HflK could
Y89_0475	COG1289	transmembrane transporter activity
Y89_0476	COG0513	Belongs to the DEAD box helicase family
Y89_0478	COG4067	protein conserved in archaea
Y89_0478	COG0189	ligase activity
Y89_0479	COG0477	Major facilitator Superfamily
Y89_0480	COG0542	response to heat
Y89_0482	COG0204	Acyl-transferase
Y89_0484	COG0745	RESPONSE REGULATOR receiver
Y89_0485	COG2205	protein histidine kinase activity
Y89_0486	COG4452	Inner membrane protein CreD
Y89_0491	COG4774	siderophore transport
Y89_0492	COG3712	iron ion homeostasis
Y89_0493	COG1595	DNA-templated transcription, initiation
Y89_0494	COG0625	glutathione transferase activity
Y89_0496	COG1309	transcriptional regulator
Y89_0497	COG1953	Uracil, thiamine, allantoin
Y89_0501	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Y89_0509	COG2005	Transcriptional regulator
Y89_0509	COG3585	molybdate ion transport
Y89_0510	COG5544	Lipoprotein
Y89_0511	COG1040	competence protein
Y89_0515	COG0511	ligase activity, forming carbon-carbon bonds
Y89_0518	COG1984	allophanate hydrolase subunit 2
Y89_0520	COG3121	Chaperone
Y89_0523	COG1073	alpha beta
Y89_0523	COG2226	methyltransferase
Y89_0527	COG1960	acyl-CoA dehydrogenase activity
Y89_0528	COG1960	acyl-CoA dehydrogenase activity
Y89_0529	COG1960	acyl-CoA dehydrogenase activity
Y89_0531	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Y89_0531	COG1648	precorrin-2 dehydrogenase activity
Y89_0548	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Y89_0549	COG0583	DNA-binding transcription factor activity
Y89_0550	COG2258	MOSC domain
Y89_0552	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Y89_0556	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Y89_0558	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Y89_0569	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Y89_0570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Y89_0572	COG3622	Belongs to the hyi family
Y89_0573	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Y89_0581	COG2081	HI0933 family
Y89_0583	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Y89_0584	COG3152	Membrane
Y89_0585	COG4977	sequence-specific DNA binding
Y89_0585	COG1917	Cupin 2, conserved barrel domain protein
Y89_0586	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Y89_0596	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Y89_0601	COG2826	transposase and inactivated derivatives, IS30 family
Y89_0621	COG3772	lysozyme
Y89_0646	COG3344	reverse transcriptase
Y89_0651	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Y89_0654	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Y89_0658	COG2719	SpoVR family
Y89_0660	COG2766	serine protein kinase
Y89_0672	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Y89_0675	COG2197	response regulator
Y89_0677	COG3842	ATPase activity
Y89_0679	COG1176	ABC-type spermidine putrescine transport system, permease component I
Y89_0681	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Y89_0703	COG3179	chitinase
Y89_0726	COG1765	OsmC-like protein
Y89_0729	COG0537	adenosine 5'-monophosphoramidase activity
Y89_0731	COG0300	oxidoreductase activity
Y89_0740	COG0739	heme binding
Y89_0782	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Y89_0789	COG2814	Major facilitator Superfamily
Y89_0794	COG1021	2,3-dihydroxybenzoate-AMP ligase
Y89_0796	COG3433	isochorismatase activity
Y89_0796	COG2226	methyltransferase
Y89_0796	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Y89_0797	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Y89_0797	COG2226	methyltransferase
Y89_0797	COG3433	isochorismatase activity
Y89_0815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y89_0816	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y89_0818	COG2706	6-phosphogluconolactonase activity
Y89_0822	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Y89_0823	COG1960	acyl-CoA dehydrogenase activity
Y89_0825	COG4191	Histidine kinase
Y89_0826	COG4566	intracellular signal transduction
Y89_0827	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y89_0828	COG0765	amino acid transport
Y89_0829	COG0765	amino acid transport
Y89_0833	COG1012	belongs to the aldehyde dehydrogenase family
Y89_0834	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Y89_0835	COG2271	Major facilitator Superfamily
Y89_0844	COG2226	methyltransferase
Y89_0846	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Y89_0849	COG0251	oxidation-reduction process
Y89_0851	COG0693	protein deglycase activity
Y89_0852	COG0492	ferredoxin-NADP+ reductase activity
Y89_0853	COG1959	2 iron, 2 sulfur cluster binding
Y89_0859	COG0154	amidase activity
Y89_0860	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_0861	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Y89_0862	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Y89_0863	COG4592	Periplasmic binding protein
Y89_0864	COG1120	ATPase activity
Y89_0866	COG1629	transport
Y89_0866	COG4774	siderophore transport
Y89_0868	COG4991	sh3 domain protein
Y89_0869	COG1063	alcohol dehydrogenase
Y89_0871	COG0022	dehydrogenase e1 component
Y89_0873	COG3199	ATP-NAD kinase
Y89_0875	COG3284	Transcriptional regulator
Y89_0880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y89_0886	COG2814	Major facilitator Superfamily
Y89_0887	COG1846	Transcriptional regulator
Y89_0889	COG3278	Belongs to the heme-copper respiratory oxidase family
Y89_0890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Y89_0892	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Y89_0895	COG3971	2-oxopent-4-enoate hydratase activity
Y89_0896	COG2271	Major facilitator Superfamily
Y89_0898	COG3384	dioxygenase
Y89_0899	COG1012	belongs to the aldehyde dehydrogenase family
Y89_0907	COG1611	Belongs to the LOG family
Y89_0919	COG2259	Doxx family
Y89_0921	COG2205	protein histidine kinase activity
Y89_0922	COG0745	RESPONSE REGULATOR receiver
Y89_0926	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_0927	COG1063	alcohol dehydrogenase
Y89_0928	COG2271	Major facilitator Superfamily
Y89_0935	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_0936	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Y89_0939	COG3121	Chaperone
Y89_0940	COG3188	usher protein
Y89_0944	COG2197	response regulator
Y89_0952	COG0531	amino acid
Y89_0956	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Y89_0957	COG3094	Invasion gene expression up-regulator, SirB
Y89_0958	COG3047	cAMP biosynthetic process
Y89_0964	COG3118	belongs to the thioredoxin family
Y89_0965	COG2264	protein methyltransferase activity
Y89_0968	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Y89_0968	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Y89_0973	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Y89_0974	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Y89_0976	COG3577	Aspartyl protease
Y89_0981	COG0142	geranyltranstransferase activity
Y89_0983	COG4948	Mandelate Racemase Muconate Lactonizing
Y89_0987	COG1131	(ABC) transporter
Y89_0988	COG5002	protein histidine kinase activity
Y89_0992	COG0745	RESPONSE REGULATOR receiver
Y89_0994	COG3228	Belongs to the MtfA family
Y89_0995	COG0586	Pfam SNARE associated Golgi protein
Y89_0998	COG0456	acetyltransferase
Y89_1000	COG4303	Ethanolamine ammonia lyase large subunit
Y89_1001	COG0531	amino acid
Y89_1002	COG1012	belongs to the aldehyde dehydrogenase family
Y89_1003	COG3284	Transcriptional regulator
Y89_1004	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Y89_1007	COG0702	epimerase
Y89_1011	COG1346	cytolysis
Y89_1013	COG0586	Pfam SNARE associated Golgi protein
Y89_1021	COG0768	penicillin binding
Y89_1022	COG0772	Belongs to the SEDS family
Y89_1023	COG2951	lytic endotransglycosylase activity
Y89_1025	COG1686	Belongs to the peptidase S11 family
Y89_1031	COG2951	lytic endotransglycosylase activity
Y89_1037	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Y89_1039	COG4535	Mg2 and Co2 transporter CorC
Y89_1041	COG1702	phosphate starvation-inducible protein PhoH
Y89_1047	COG0351	phosphomethylpyrimidine kinase
Y89_1050	COG1960	acyl-CoA dehydrogenase activity
Y89_1052	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Y89_1060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Y89_1062	COG1643	Atp-dependent helicase
Y89_1071	COG3416	Protein conserved in bacteria
Y89_1073	COG0513	Belongs to the DEAD box helicase family
Y89_1075	COG2197	response regulator
Y89_1076	COG2200	EAL domain
Y89_1076	COG2202	Pas domain
Y89_1076	COG2199	diguanylate cyclase activity
Y89_1077	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y89_1077	COG2205	protein histidine kinase activity
Y89_1081	COG1946	Acyl-CoA thioesterase
Y89_1085	COG4521	taurine ABC transporter
Y89_1087	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Y89_1088	COG2175	clavaminate synthase activity
Y89_1089	COG1297	OPT oligopeptide transporter protein
Y89_1090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Y89_1093	COG1271	oxidase subunit
Y89_1094	COG1294	oxidase, subunit
Y89_1096	COG2207	Transcriptional regulator
Y89_1098	COG0183	Belongs to the thiolase family
Y89_1099	COG0318	PFAM AMP-dependent synthetase and ligase
Y89_1104	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Y89_1106	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Y89_1108	COG0521	Mo-molybdopterin cofactor biosynthetic process
Y89_1109	COG0303	'Molybdopterin
Y89_1122	COG4772	TonB-dependent receptor
Y89_1123	COG3712	iron ion homeostasis
Y89_1124	COG1595	DNA-templated transcription, initiation
Y89_1126	COG0697	spore germination
Y89_1128	COG0583	DNA-binding transcription factor activity
Y89_1132	COG1566	PFAM secretion protein HlyD family protein
Y89_1143	COG0300	oxidoreductase activity
Y89_1144	COG2226	methyltransferase
Y89_1147	COG2197	response regulator
Y89_1148	COG3850	Histidine kinase
Y89_1150	COG2223	nitrite transmembrane transporter activity
Y89_1151	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Y89_1152	COG1140	nitrate reductase beta subunit
Y89_1153	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Y89_1154	COG2181	nitrate reductase activity
Y89_1158	COG4771	TonB-dependent receptor
Y89_1159	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y89_1164	COG0318	PFAM AMP-dependent synthetase and ligase
Y89_1166	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y89_1179	COG0583	DNA-binding transcription factor activity
Y89_1185	COG0471	metal ion transport
Y89_1185	COG0490	domain, Protein
Y89_1186	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Y89_1187	COG4120	Belongs to the binding-protein-dependent transport system permease family
Y89_1198	COG0795	lipopolysaccharide-transporting ATPase activity
Y89_1199	COG0795	lipopolysaccharide-transporting ATPase activity
Y89_1201	COG2200	EAL domain
Y89_1204	COG1862	Preprotein translocase
Y89_1207	COG3134	Outer membrane lipoprotein
Y89_1210	COG1045	serine acetyltransferase
Y89_1228	COG0436	Aminotransferase
Y89_1231	COG0667	Aldo Keto reductase
Y89_1239	COG0739	heme binding
Y89_1241	COG2847	Copper chaperone PCu(A)C
Y89_1243	COG1335	isochorismatase
Y89_1246	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Y89_1248	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Y89_1249	COG0583	DNA-binding transcription factor activity
Y89_1259	COG2132	Multicopper oxidase
Y89_1260	COG0590	tRNA wobble adenosine to inosine editing
Y89_1267	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Y89_1267	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Y89_1268	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Y89_1269	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Y89_1270	COG2188	Transcriptional regulator
Y89_1278	COG0477	Major facilitator Superfamily
Y89_1279	COG4536	flavin adenine dinucleotide binding
Y89_1281	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Y89_1286	COG1607	acyl-coa hydrolase
Y89_1290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Y89_1296	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Y89_1301	COG2255	four-way junction helicase activity
Y89_1303	COG4681	YaeQ
Y89_1304	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Y89_1312	COG2197	response regulator
Y89_1313	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Y89_1317	COG0477	Major facilitator Superfamily
Y89_1324	COG2203	Gaf domain
Y89_1324	COG3706	GGDEF domain
Y89_1324	COG5001	Diguanylate cyclase
Y89_1324	COG4251	negative regulation of phosphorylation
Y89_1325	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Y89_1331	COG3064	Membrane
Y89_1331	COG1073	alpha beta
Y89_1331	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Y89_1334	COG2885	chlorophyll binding
Y89_1337	COG0789	Transcriptional regulator
Y89_1341	COG1214	PFAM Peptidase M22, glycoprotease
Y89_1343	COG1801	Protein of unknown function DUF72
Y89_1344	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Y89_1349	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y89_1358	COG2166	iron-sulfur cluster assembly
Y89_1362	COG1393	Belongs to the ArsC family
Y89_1366	COG0025	NhaP-type Na H and K H
Y89_1367	COG0436	Aminotransferase
Y89_1369	COG0024	Methionine aminopeptidase
Y89_1385	COG1115	amino acid carrier protein
Y89_1395	COG2391	methyltransferase activity
Y89_1396	COG0583	DNA-binding transcription factor activity
Y89_1397	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Y89_1398	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Y89_1408	COG1546	Belongs to the CinA family
Y89_1412	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Y89_1413	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Y89_1414	COG3530	Putative quorum-sensing-regulated virulence factor
Y89_1417	COG1177	transmembrane transport
Y89_1418	COG1176	ABC-type spermidine putrescine transport system, permease component I
Y89_1424	COG0069	glutamate synthase activity
Y89_1429	COG0531	amino acid
Y89_1430	COG2169	Transcriptional regulator
Y89_1430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Y89_1431	COG0477	Major facilitator Superfamily
Y89_1432	COG0583	DNA-binding transcription factor activity
Y89_1433	COG1960	acyl-CoA dehydrogenase activity
Y89_1434	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Y89_1435	COG1024	Enoyl-CoA hydratase
Y89_1436	COG1250	3-hydroxyacyl-CoA dehydrogenase
Y89_1437	COG0183	Belongs to the thiolase family
Y89_1439	COG0583	DNA-binding transcription factor activity
Y89_1446	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Y89_1453	COG2814	Major facilitator Superfamily
Y89_1461	COG0583	DNA-binding transcription factor activity
Y89_1463	COG0084	hydrolase, TatD family'
Y89_1464	COG1609	Transcriptional regulator
Y89_1466	COG1105	Belongs to the carbohydrate kinase PfkB family
Y89_1467	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Y89_1467	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Y89_1467	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Y89_1489	COG3842	ATPase activity
Y89_1493	COG0243	molybdopterin cofactor binding
Y89_1494	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Y89_1495	COG2223	nitrite transmembrane transporter activity
Y89_1497	COG2906	2 iron, 2 sulfur cluster binding
Y89_1498	COG0450	alkyl hydroperoxide reductase
Y89_1504	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y89_1511	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Y89_1512	COG2264	protein methyltransferase activity
Y89_1514	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Y89_1525	COG0489	protein tyrosine kinase activity
Y89_1534	COG0791	NLP P60 protein
Y89_1537	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Y89_1538	COG0668	transmembrane transport
Y89_1539	COG0477	Major facilitator Superfamily
Y89_1540	COG0513	Belongs to the DEAD box helicase family
Y89_1544	COG5002	protein histidine kinase activity
Y89_1544	COG0784	Response regulator, receiver
Y89_1544	COG2205	protein histidine kinase activity
Y89_1545	COG1363	Peptidase, m42
Y89_1547	COG0367	asparagine synthase
Y89_1552	COG0183	Belongs to the thiolase family
Y89_1556	COG0450	alkyl hydroperoxide reductase
Y89_1557	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Y89_1558	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Y89_1560	COG0431	NADPH-dependent FMN reductase
Y89_1561	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Y89_1563	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Y89_1568	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Y89_1574	COG0583	DNA-binding transcription factor activity
Y89_1575	COG1380	Effector of murein hydrolase LrgA
Y89_1576	COG1346	cytolysis
Y89_1580	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_1581	COG1024	Enoyl-CoA hydratase
Y89_1583	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
Y89_1592	COG0508	dehydrogenase complex catalyzes the overall conversion of
Y89_1600	COG1629	transport
Y89_1611	COG0583	DNA-binding transcription factor activity
Y89_1626	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Y89_1627	COG3639	organic phosphonate transmembrane transporter activity
Y89_1628	COG2188	Transcriptional regulator
Y89_1629	COG3624	Phosphonate C-P lyase system protein PhnG
Y89_1631	COG3626	phosphonate metabolism
Y89_1632	COG3627	carbon phosphorus lyase activity
Y89_1633	COG4107	phosphonate C-P lyase system protein PhnK
Y89_1634	COG4778	phosphonate C-P lyase system protein PhnL
Y89_1635	COG3454	Phosphonate metabolism
Y89_1637	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Y89_1651	COG0697	spore germination
Y89_1656	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
Y89_1660	COG0784	Response regulator, receiver
Y89_1660	COG0835	chemotaxis
Y89_1663	COG0745	RESPONSE REGULATOR receiver
Y89_1665	COG0514	ATP-dependent DNA helicase (RecQ)
Y89_1666	COG5001	Diguanylate cyclase
Y89_1666	COG4251	negative regulation of phosphorylation
Y89_1666	COG3706	GGDEF domain
Y89_1666	COG2203	Gaf domain
Y89_1670	COG1752	Esterase of the alpha-beta hydrolase superfamily
Y89_1678	COG2124	cytochrome p450
Y89_1679	COG4221	oxidoreductase activity
Y89_1688	COG0583	DNA-binding transcription factor activity
Y89_1694	COG3639	organic phosphonate transmembrane transporter activity
Y89_1696	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Y89_1697	COG2084	Dehydrogenase
Y89_1700	COG0589	response to stress
Y89_1709	COG2814	Major facilitator Superfamily
Y89_1710	COG2030	dehydratase
Y89_1711	COG2267	carboxylic ester hydrolase activity
Y89_1712	COG0318	PFAM AMP-dependent synthetase and ligase
Y89_1713	COG0318	PFAM AMP-dependent synthetase and ligase
Y89_1715	COG1643	Atp-dependent helicase
Y89_1717	COG0537	adenosine 5'-monophosphoramidase activity
Y89_1718	COG3501	Rhs element vgr protein
Y89_1726	COG1595	DNA-templated transcription, initiation
Y89_1740	COG1201	RNA secondary structure unwinding
Y89_1741	COG2205	protein histidine kinase activity
Y89_1741	COG0784	Response regulator, receiver
Y89_1744	COG4772	TonB-dependent receptor
Y89_1747	COG2076	Multidrug Resistance protein
Y89_1748	COG0385	Bile acid
Y89_1756	COG2200	EAL domain
Y89_1758	COG0604	alcohol dehydrogenase
Y89_1758	COG3321	synthase
Y89_1759	COG0560	Phosphoserine phosphatase
Y89_1762	COG1176	ABC-type spermidine putrescine transport system, permease component I
Y89_1768	COG0564	pseudouridine synthase activity
Y89_1770	COG2894	cell division
Y89_1772	COG1560	Kdo2-lipid A biosynthetic process
Y89_1775	COG2853	Lipoprotein
Y89_1779	COG3162	membrane
Y89_1780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Y89_1787	COG1132	(ABC) transporter
Y89_1789	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Y89_1794	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Y89_1797	COG0438	transferase activity, transferring glycosyl groups
Y89_1797	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Y89_1803	COG1127	ABC transporter
Y89_1804	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Y89_1805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Y89_1807	COG0778	Nitroreductase
Y89_1811	COG0745	RESPONSE REGULATOR receiver
Y89_1813	COG2350	Protein conserved in bacteria
Y89_1815	COG0613	PHP domain protein
Y89_1816	COG0009	L-threonylcarbamoyladenylate synthase
Y89_1818	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Y89_1824	COG0745	RESPONSE REGULATOR receiver
Y89_1825	COG2205	protein histidine kinase activity
Y89_1828	COG0395	ABC-type sugar transport system, permease component
Y89_1829	COG3842	ATPase activity
Y89_1831	COG0676	glucose-6-phosphate 1-epimerase activity
Y89_1839	COG3706	GGDEF domain
Y89_1840	COG0786	glutamate:sodium symporter activity
Y89_1843	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_1846	COG0402	S-adenosylhomocysteine deaminase activity
Y89_1852	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Y89_1857	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Y89_1858	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Y89_1859	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Y89_1860	COG2089	acid synthase
Y89_1862	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Y89_1864	COG1083	cytidylyl-transferase
Y89_1865	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_1870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Y89_1877	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Y89_1884	COG0583	DNA-binding transcription factor activity
Y89_1887	COG0596	Alpha beta hydrolase
Y89_1888	COG0800	Aldolase
Y89_1891	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_1895	COG0583	DNA-binding transcription factor activity
Y89_1896	COG0251	oxidation-reduction process
Y89_1900	COG2226	methyltransferase
Y89_1908	COG0285	dihydrofolate synthase activity
Y89_1909	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Y89_1910	COG1286	toxin biosynthetic process
Y89_1927	COG1902	pentaerythritol trinitrate reductase activity
Y89_1927	COG0446	pyridine nucleotide-disulphide oxidoreductase
Y89_1932	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Y89_1934	COG3139	Protein of unknown function (DUF1315)
Y89_1936	COG0308	aminopeptidase N
Y89_1941	COG5002	protein histidine kinase activity
Y89_1942	COG0745	RESPONSE REGULATOR receiver
Y89_1949	COG0714	Associated with various cellular activities
Y89_1953	COG1335	isochorismatase
Y89_1955	COG2342	PFAM TM1410 hypothetical-related protein
Y89_1960	COG0297	glycogen (starch) synthase activity
Y89_1970	COG3130	regulation of translation
Y89_1972	COG2027	D-alanyl-D-alanine carboxypeptidase
Y89_1973	COG3171	Protein conserved in bacteria
Y89_1974	COG2197	response regulator
Y89_1975	COG2205	protein histidine kinase activity
Y89_1975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y89_1980	COG0004	ammonium transporteR
Y89_1982	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Y89_1984	COG0625	glutathione transferase activity
Y89_1985	COG1309	transcriptional regulator
Y89_1990	COG0521	Mo-molybdopterin cofactor biosynthetic process
Y89_1994	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Y89_1995	COG1070	Carbohydrate kinase
Y89_1999	COG0741	lytic transglycosylase activity
Y89_2002	COG0589	response to stress
Y89_2017	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Y89_2019	COG1113	amino acid transport
Y89_2026	COG1477	protein flavinylation
Y89_2029	COG0584	glycerophosphoryl diester phosphodiesterase
Y89_2032	COG4591	ABC-type transport system involved in lipoprotein release permease component
Y89_2034	COG4591	ABC-type transport system involved in lipoprotein release permease component
Y89_2036	COG2333	competence protein COMEC
Y89_2036	COG0658	competence protein
Y89_2037	COG0811	peptide transport
Y89_2038	COG0848	biopolymer transport protein
Y89_2042	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Y89_2044	COG1530	ribonuclease E activity
Y89_2047	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Y89_2047	COG0616	signal peptide processing
Y89_2049	COG1399	metal-binding, possibly nucleic acid-binding protein
Y89_2055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Y89_2057	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Y89_2061	COG0084	hydrolase, TatD family'
Y89_2078	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Y89_2081	COG0183	Belongs to the thiolase family
Y89_2083	COG2233	PERMEase
Y89_2085	COG3038	cytochrome b561
Y89_2089	COG2814	Major facilitator Superfamily
Y89_2090	COG1902	pentaerythritol trinitrate reductase activity
Y89_2091	COG1309	transcriptional regulator
Y89_2097	COG4160	amino acid transport
Y89_2098	COG4215	(ABC) transporter
Y89_2099	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y89_2100	COG1473	amidohydrolase
Y89_2101	COG0583	DNA-binding transcription factor activity
Y89_2102	COG0840	transmembrane signaling receptor activity
Y89_2108	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Y89_2110	COG1120	ATPase activity
Y89_2116	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Y89_2122	COG2885	chlorophyll binding
Y89_2122	COG3047	cAMP biosynthetic process
Y89_2123	COG2197	response regulator
Y89_2125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Y89_2126	COG1595	DNA-templated transcription, initiation
Y89_2132	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Y89_2133	COG1960	acyl-CoA dehydrogenase activity
Y89_2134	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Y89_2137	COG1309	transcriptional regulator
Y89_2143	COG0583	DNA-binding transcription factor activity
Y89_2145	COG0583	DNA-binding transcription factor activity
Y89_2147	COG0714	Associated with various cellular activities
Y89_2152	COG3706	GGDEF domain
Y89_2157	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Y89_2158	COG2259	Doxx family
Y89_2161	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Y89_2164	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Y89_2165	COG4181	ATPase activity
Y89_2171	COG1764	response to oxidative stress
Y89_2172	COG1846	Transcriptional regulator
Y89_2173	COG0583	DNA-binding transcription factor activity
Y89_2175	COG0583	DNA-binding transcription factor activity
Y89_2177	COG3214	Protein conserved in bacteria
Y89_2178	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Y89_2180	COG1024	Enoyl-CoA hydratase
Y89_2182	COG3384	dioxygenase
Y89_2190	COG2866	Carboxypeptidase
Y89_2193	COG0436	Aminotransferase
Y89_2195	COG0386	Belongs to the glutathione peroxidase family
Y89_2196	COG1846	Transcriptional regulator
Y89_2197	COG0784	Response regulator, receiver
Y89_2197	COG5002	protein histidine kinase activity
Y89_2197	COG2205	protein histidine kinase activity
Y89_2198	COG2255	four-way junction helicase activity
Y89_2199	COG1956	GAF domain-containing protein
Y89_2200	COG0625	glutathione transferase activity
Y89_2216	COG0625	glutathione transferase activity
Y89_2217	COG1131	(ABC) transporter
Y89_2218	COG0842	Transport permease protein
Y89_2227	COG2188	Transcriptional regulator
Y89_2229	COG2853	Lipoprotein
Y89_2231	COG0745	RESPONSE REGULATOR receiver
Y89_2245	COG3655	Transcriptional regulator
Y89_2253	COG2116	formate transmembrane transporter activity
Y89_2254	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Y89_2263	COG1051	belongs to the nudix hydrolase family
Y89_2265	COG1250	3-hydroxyacyl-CoA dehydrogenase
Y89_2265	COG1024	Enoyl-CoA hydratase
Y89_2268	COG2837	iron assimilation
Y89_2285	COG1238	metal cluster binding
Y89_2287	COG1295	ribonuclease BN
Y89_2293	COG0024	Methionine aminopeptidase
Y89_2311	COG2003	Belongs to the UPF0758 family
Y89_2322	COG1192	Involved in chromosome partitioning
Y89_2325	COG4959	Type IV secretory pathway protease TraF
Y89_2333	COG0583	DNA-binding transcription factor activity
Y89_2337	COG4962	Type ii secretion system protein e
Y89_2338	COG3838	Conjugal transfer protein Trbc
Y89_2340	COG3451	type IV secretory pathway VirB4
Y89_2345	COG2948	multi-organism process
Y89_2358	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Y89_2358	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Y89_2369	COG0789	Transcriptional regulator
Y89_2371	COG0446	pyridine nucleotide-disulphide oxidoreductase
Y89_2371	COG1902	pentaerythritol trinitrate reductase activity
Y89_2372	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Y89_2373	COG0243	molybdopterin cofactor binding
Y89_2374	COG1733	regulation of RNA biosynthetic process
Y89_2377	COG1280	lysine exporter protein (LysE YggA)
Y89_2378	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Y89_2380	COG0542	response to heat
Y89_2394	COG1607	acyl-coa hydrolase
Y89_2395	COG1959	2 iron, 2 sulfur cluster binding
Y89_2397	COG2819	hydrolase of the alpha beta superfamily
Y89_2401	COG3501	Rhs element vgr protein
Y89_2402	COG3209	COG3209 Rhs family protein
Y89_2406	COG0583	DNA-binding transcription factor activity
Y89_2408	COG4106	trans-aconitate 2-methyltransferase activity
Y89_2410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Y89_2411	COG1459	type II secretion system
Y89_2413	COG2165	general secretion pathway protein
Y89_2421	COG0720	synthase
Y89_2422	COG3604	Transcriptional regulator
Y89_2431	COG0745	RESPONSE REGULATOR receiver
Y89_2434	COG0840	transmembrane signaling receptor activity
Y89_2435	COG2056	Na+-H+ antiporter family
Y89_2438	COG2226	methyltransferase
Y89_2457	COG2153	protein acetylation
Y89_2458	COG2850	peptidyl-arginine hydroxylation
Y89_2466	COG1278	Cold shock
Y89_2468	COG0542	response to heat
Y89_2469	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Y89_2472	COG0492	ferredoxin-NADP+ reductase activity
Y89_2475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Y89_2478	COG0435	Glutathione S-transferase
Y89_2479	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Y89_2480	COG2920	part of a sulfur-relay system
Y89_2487	COG0583	DNA-binding transcription factor activity
Y89_2489	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Y89_2491	COG1960	acyl-CoA dehydrogenase activity
Y89_2492	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Y89_2494	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Y89_2497	COG2197	response regulator
Y89_2498	COG4771	TonB-dependent receptor
Y89_2505	COG0582	viral genome integration into host DNA
Y89_2506	COG2161	toxin-antitoxin pair type II binding
Y89_2507	COG4115	mRNA cleavage
Y89_2513	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Y89_2520	COG1024	Enoyl-CoA hydratase
Y89_2521	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Y89_2522	COG1960	acyl-CoA dehydrogenase activity
Y89_2523	COG0789	Transcriptional regulator
Y89_2527	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_2532	COG1063	alcohol dehydrogenase
Y89_2534	COG2124	cytochrome p450
Y89_2537	COG1012	belongs to the aldehyde dehydrogenase family
Y89_2542	COG0583	DNA-binding transcription factor activity
Y89_2543	COG0386	Belongs to the glutathione peroxidase family
Y89_2544	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_2547	COG4447	cellulose binding
Y89_2550	COG1024	Enoyl-CoA hydratase
Y89_2551	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_2552	COG2814	Major facilitator Superfamily
Y89_2553	COG0445	tRNA wobble uridine modification
Y89_2554	COG1309	transcriptional regulator
Y89_2555	COG2124	cytochrome p450
Y89_2557	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_2564	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Y89_2566	COG2814	Major facilitator Superfamily
Y89_2575	COG2814	Major facilitator Superfamily
Y89_2579	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_2580	COG0179	Fumarylacetoacetate (FAA) hydrolase
Y89_2582	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Y89_2584	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_2585	COG0318	PFAM AMP-dependent synthetase and ligase
Y89_2588	COG0179	Fumarylacetoacetate (FAA) hydrolase
Y89_2589	COG1250	3-hydroxyacyl-CoA dehydrogenase
Y89_2590	COG0183	Belongs to the thiolase family
Y89_2592	COG2124	cytochrome p450
Y89_2594	COG1960	acyl-CoA dehydrogenase activity
Y89_2596	COG1024	Enoyl-CoA hydratase
Y89_2597	COG1960	acyl-CoA dehydrogenase activity
Y89_2601	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_2604	COG2205	protein histidine kinase activity
Y89_2604	COG0784	Response regulator, receiver
Y89_2604	COG2198	Histidine kinase
Y89_2604	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y89_2607	COG2249	NAD(P)H dehydrogenase (quinone) activity
Y89_2610	COG1522	sequence-specific DNA binding
Y89_2616	COG4191	Histidine kinase
Y89_2620	COG5001	Diguanylate cyclase
Y89_2620	COG3706	GGDEF domain
Y89_2620	COG4251	negative regulation of phosphorylation
Y89_2620	COG2203	Gaf domain
Y89_2625	COG0659	secondary active sulfate transmembrane transporter activity
Y89_2633	COG0318	PFAM AMP-dependent synthetase and ligase
Y89_2635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Y89_2637	COG0183	Belongs to the thiolase family
Y89_2638	COG1960	acyl-CoA dehydrogenase activity
Y89_2645	COG0346	lactoylglutathione lyase activity
Y89_2646	COG0708	Exodeoxyribonuclease III
Y89_2648	COG0729	surface antigen
Y89_2650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Y89_2651	COG2267	carboxylic ester hydrolase activity
Y89_2652	COG0671	phosphoesterase, PA-phosphatase related
Y89_2652	COG2453	phosphatase
Y89_2655	COG4589	Belongs to the CDS family
Y89_2656	COG0667	Aldo Keto reductase
Y89_2658	COG1115	amino acid carrier protein
Y89_2660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Y89_2664	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y89_2665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y89_2666	COG1538	Outer membrane efflux protein
Y89_2678	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Y89_2678	COG0543	2 iron, 2 sulfur cluster binding
Y89_2679	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Y89_2680	COG4638	Rieske (2fe-2S)
Y89_2683	COG4948	Mandelate Racemase Muconate Lactonizing
Y89_2685	COG3485	protocatechuate 3,4-dioxygenase
Y89_2692	COG2807	transmembrane transport
Y89_2693	COG0590	tRNA wobble adenosine to inosine editing
Y89_2696	COG2318	DinB family
Y89_2718	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Y89_2719	COG2863	cytochrome
Y89_2720	COG3258	Cytochrome c
Y89_2721	COG0642	Histidine kinase
Y89_2722	COG0745	RESPONSE REGULATOR receiver
Y89_2728	COG0625	glutathione transferase activity
Y89_2732	COG0583	DNA-binding transcription factor activity
Y89_2733	COG1595	DNA-templated transcription, initiation
Y89_2734	COG3712	iron ion homeostasis
Y89_2739	COG3210	domain, Protein
Y89_2745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Y89_2747	COG2382	esterase
Y89_2751	COG0583	DNA-binding transcription factor activity
Y89_2755	COG1760	l-serine dehydratase
Y89_2756	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Y89_2763	COG2217	Heavy metal translocating P-type atpase
Y89_2766	COG0583	DNA-binding transcription factor activity
Y89_2769	COG1566	PFAM secretion protein HlyD family protein
Y89_2780	COG1335	isochorismatase
Y89_2781	COG1335	isochorismatase
Y89_2783	COG0583	DNA-binding transcription factor activity
Y89_2791	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Y89_2792	COG1121	(ABC) transporter
Y89_2810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y89_2815	COG0735	belongs to the Fur family
Y89_2817	COG1304	FMN binding
Y89_2823	COG4566	intracellular signal transduction
Y89_2826	COG3501	Rhs element vgr protein
Y89_2846	COG3829	transcription factor binding
Y89_2847	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Y89_2848	COG0584	glycerophosphoryl diester phosphodiesterase
Y89_2849	COG2011	ABC-type metal ion transport system permease component
Y89_2851	COG1464	Belongs to the NlpA lipoprotein family
Y89_2884	COG4373	Mu-like prophage FluMu protein gp28
Y89_2886	COG2369	cell adhesion
Y89_2910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Y89_2911	COG1070	Carbohydrate kinase
Y89_2912	COG0246	Mannitol dehydrogenase
Y89_2915	COG1175	transmembrane transport
Y89_2919	COG4771	TonB-dependent receptor
Y89_2922	COG1917	Cupin 2, conserved barrel domain protein
Y89_2922	COG4977	sequence-specific DNA binding
Y89_2925	COG1116	anion transmembrane transporter activity
Y89_2926	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Y89_2927	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Y89_2931	COG1012	belongs to the aldehyde dehydrogenase family
Y89_2934	COG3265	gluconokinase activity
Y89_2935	COG1609	Transcriptional regulator
Y89_2937	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Y89_2938	COG0583	DNA-binding transcription factor activity
Y89_2942	COG1396	sequence-specific DNA binding
Y89_2944	COG2175	clavaminate synthase activity
Y89_2946	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Y89_2947	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Y89_2952	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Y89_2952	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Y89_2954	COG3469	chitinase activity
Y89_2956	COG1053	succinate dehydrogenase
Y89_2959	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Y89_2965	COG4772	TonB-dependent receptor
Y89_2974	COG0431	NADPH-dependent FMN reductase
Y89_2975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Y89_2977	COG0640	Transcriptional regulator
Y89_2978	COG2207	Transcriptional regulator
Y89_2979	COG1064	alcohol dehydrogenase
Y89_2984	COG1309	transcriptional regulator
Y89_2986	COG2329	Antibiotic biosynthesis monooxygenase
Y89_2993	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Y89_2995	COG1609	Transcriptional regulator
Y89_3001	COG0252	asparaginase activity
Y89_3002	COG1115	amino acid carrier protein
Y89_3014	COG0728	peptidoglycan biosynthetic process
Y89_3026	COG2258	MOSC domain
Y89_3030	COG2801	Transposase and inactivated derivatives
Y89_3033	COG2508	Transcriptional regulator
Y89_3035	COG4447	cellulose binding
Y89_3036	COG2409	Drug exporters of the RND superfamily
Y89_3040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Y89_3043	COG2072	flavoprotein involved in K transport
Y89_3046	COG0531	amino acid
Y89_3047	COG1012	belongs to the aldehyde dehydrogenase family
Y89_3048	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Y89_3051	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Y89_3052	COG3162	membrane
Y89_3053	COG0318	PFAM AMP-dependent synthetase and ligase
Y89_3054	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_3060	COG3008	intermembrane lipid transfer
Y89_3061	COG2995	paraquat-inducible protein a
Y89_3062	COG1012	belongs to the aldehyde dehydrogenase family
Y89_3064	COG4948	Mandelate Racemase Muconate Lactonizing
Y89_3065	COG2271	Major facilitator Superfamily
Y89_3068	COG3618	amidohydrolase
Y89_3069	COG2271	Major facilitator Superfamily
Y89_3076	COG0765	amino acid transport
Y89_3077	COG0765	amino acid transport
Y89_3080	COG2084	Dehydrogenase
Y89_3082	COG2130	NADP-dependent
Y89_3083	COG1309	transcriptional regulator
Y89_3087	COG0517	IMP dehydrogenase activity
Y89_3094	COG2890	protein-(glutamine-N5) methyltransferase activity
Y89_3097	COG0784	Response regulator, receiver
Y89_3097	COG4191	Histidine kinase
Y89_3103	COG1363	Peptidase, m42
Y89_3112	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Y89_3120	COG3568	Endonuclease Exonuclease Phosphatase
Y89_3121	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Y89_3122	COG0392	lysyltransferase activity
Y89_3124	COG0366	Alpha amylase catalytic
Y89_3128	COG1285	pathogenesis
Y89_3134	COG0058	SHG alpha-glucan phosphorylase activity
Y89_3137	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_3138	COG1546	Belongs to the CinA family
Y89_3148	COG3121	Chaperone
Y89_3150	COG3188	usher protein
Y89_3151	COG3121	Chaperone
Y89_3153	COG3969	phosphoadenosine phosphosulfate
Y89_3154	COG1475	DNA binding
Y89_3156	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Y89_3157	COG0583	DNA-binding transcription factor activity
Y89_3161	COG1063	alcohol dehydrogenase
Y89_3163	COG2169	Transcriptional regulator
Y89_3163	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Y89_3166	COG0583	DNA-binding transcription factor activity
Y89_3171	COG1984	allophanate hydrolase subunit 2
Y89_3173	COG0028	Belongs to the TPP enzyme family
Y89_3175	COG0300	oxidoreductase activity
Y89_3182	COG2814	Major facilitator Superfamily
Y89_3184	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Y89_3188	COG0596	Alpha beta hydrolase
Y89_3189	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Y89_3190	COG0367	asparagine synthase
Y89_3192	COG1522	sequence-specific DNA binding
Y89_3195	COG1113	amino acid transport
Y89_3196	COG2010	Cytochrome c
Y89_3197	COG2010	Cytochrome c
Y89_3201	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Y89_3201	COG3153	acetyltransferase
Y89_3202	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Y89_3203	COG5001	Diguanylate cyclase
Y89_3206	COG2192	nodulation
Y89_3207	COG2814	Major facilitator Superfamily
Y89_3213	COG1104	cysteine desulfurase activity
Y89_3214	COG4172	Belongs to the ABC transporter superfamily
Y89_3215	COG4239	(ABC) transporter, permease
Y89_3216	COG4174	ABC transporter (Permease)
Y89_3218	COG4771	TonB-dependent receptor
Y89_3221	COG0583	DNA-binding transcription factor activity
Y89_3225	COG1595	DNA-templated transcription, initiation
Y89_3244	COG4397	Mu-like prophage major head subunit gpT
Y89_3249	COG4383	Mu-like prophage protein gp29
Y89_3250	COG4373	Mu-like prophage FluMu protein gp28
Y89_3252	COG0640	Transcriptional regulator
Y89_3265	COG0488	(ABC) transporter
Y89_3275	COG5566	PFAM Mor transcription activator
Y89_3276	COG2207	Transcriptional regulator
Y89_3280	COG0564	pseudouridine synthase activity
Y89_3282	COG0531	amino acid
Y89_3283	COG0174	glutamine synthetase
Y89_3287	COG0028	Belongs to the TPP enzyme family
Y89_3290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Y89_3294	COG1522	sequence-specific DNA binding
Y89_3302	COG1309	transcriptional regulator
Y89_3303	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y89_3304	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y89_3306	COG3204	pilus organization
Y89_3307	COG0789	Transcriptional regulator
Y89_3308	COG1960	acyl-CoA dehydrogenase activity
Y89_3309	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Y89_3315	COG0179	Fumarylacetoacetate (FAA) hydrolase
Y89_3317	COG2271	Major facilitator Superfamily
Y89_3318	COG3829	transcription factor binding
Y89_3318	COG3290	protein histidine kinase activity
Y89_3319	COG2610	gluconate transmembrane transporter activity
Y89_3320	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_3321	COG2031	fatty acid transporter
Y89_3324	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Y89_3325	COG0583	DNA-binding transcription factor activity
Y89_3326	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Y89_3327	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Y89_3331	COG2205	protein histidine kinase activity
Y89_3339	COG1012	belongs to the aldehyde dehydrogenase family
Y89_3340	COG2010	Cytochrome c
Y89_3340	COG4993	Dehydrogenase
Y89_3348	COG2205	protein histidine kinase activity
Y89_3348	COG0784	Response regulator, receiver
Y89_3352	COG2194	sulfuric ester hydrolase activity
Y89_3360	COG0488	(ABC) transporter
Y89_3363	COG0583	DNA-binding transcription factor activity
Y89_3364	COG1278	Cold shock
Y89_3374	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Y89_3375	COG1609	Transcriptional regulator
Y89_3376	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y89_3377	COG1129	ABC transporter
Y89_3378	COG1879	ABC-type sugar transport system periplasmic component
Y89_3383	COG2010	Cytochrome c
Y89_3384	COG0753	catalase activity
Y89_3388	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Y89_3389	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Y89_3390	COG2080	2 iron, 2 sulfur cluster binding
Y89_3395	COG1944	ATP diphosphatase activity
Y89_3399	COG4771	TonB-dependent receptor
Y89_3401	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Y89_3401	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Y89_3404	COG0579	oxidoreductase
Y89_3411	COG1595	DNA-templated transcription, initiation
Y89_3412	COG3712	iron ion homeostasis
Y89_3416	COG2814	Major facilitator Superfamily
Y89_3426	COG2197	response regulator
Y89_3431	COG2366	antibiotic biosynthetic process
Y89_3434	COG0625	glutathione transferase activity
Y89_3439	COG0417	DNA replication proofreading
Y89_3448	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y89_3462	COG1309	transcriptional regulator
Y89_3466	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Y89_3467	COG0583	DNA-binding transcription factor activity
Y89_3470	COG2354	Protein conserved in bacteria
Y89_3471	COG3278	Belongs to the heme-copper respiratory oxidase family
Y89_3473	COG2239	Acts as a magnesium transporter
Y89_3476	COG3706	GGDEF domain
Y89_3476	COG2203	Gaf domain
Y89_3476	COG4251	negative regulation of phosphorylation
Y89_3476	COG5001	Diguanylate cyclase
Y89_3477	COG4977	sequence-specific DNA binding
Y89_3478	COG3813	Protein conserved in bacteria
Y89_3491	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Y89_3496	COG0604	alcohol dehydrogenase
Y89_3497	COG0616	signal peptide processing
Y89_3501	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_3502	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_3503	COG0583	DNA-binding transcription factor activity
Y89_3508	COG1024	Enoyl-CoA hydratase
Y89_3510	COG0531	amino acid
Y89_3511	COG1982	Orn Lys Arg decarboxylase major
Y89_3513	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Y89_3517	COG1388	LysM domain
Y89_3517	COG0741	lytic transglycosylase activity
Y89_3518	COG4166	transmembrane transport
Y89_3519	COG4166	transmembrane transport
Y89_3520	COG4174	ABC transporter (Permease)
Y89_3521	COG4239	(ABC) transporter, permease
Y89_3522	COG4172	Belongs to the ABC transporter superfamily
Y89_3524	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Y89_3526	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Y89_3530	COG0745	RESPONSE REGULATOR receiver
Y89_3531	COG2205	protein histidine kinase activity
Y89_3532	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Y89_3539	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Y89_3543	COG0589	response to stress
Y89_3547	COG2201	protein-glutamate methylesterase activity
Y89_3549	COG2223	nitrite transmembrane transporter activity
Y89_3550	COG0515	serine threonine protein kinase
Y89_3551	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Y89_3552	COG2146	nitrite reductase [NAD(P)H] activity
Y89_3553	COG0243	molybdopterin cofactor binding
Y89_3557	COG0668	transmembrane transport
Y89_3564	COG0189	ligase activity
Y89_3564	COG4067	protein conserved in archaea
Y89_3572	COG2909	trisaccharide binding
Y89_3573	COG2909	trisaccharide binding
Y89_3580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Y89_3582	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Y89_3590	COG0519	Catalyzes the synthesis of GMP from XMP
Y89_3593	COG0667	Aldo Keto reductase
Y89_3596	COG0183	Belongs to the thiolase family
Y89_3601	COG1305	Transglutaminase-like
Y89_3603	COG2308	Evidence 4 Homologs of previously reported genes of
Y89_3604	COG0505	Belongs to the CarA family
Y89_3608	COG1317	bacterial-type flagellum organization
Y89_3630	COG4789	Type iii secretion
Y89_3639	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Y89_3640	COG4790	Type iii secretion
Y89_3641	COG4794	Type iii secretion
Y89_3642	COG4791	protein targeting
Y89_3643	COG4792	protein secretion
Y89_3663	COG2815	serine threonine protein kinase
Y89_3663	COG0515	serine threonine protein kinase
Y89_3671	COG2204	response regulator
Y89_3679	COG0625	glutathione transferase activity
Y89_3680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Y89_3683	COG3135	benzoate transporter
Y89_3686	COG2130	NADP-dependent
Y89_3690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Y89_3698	COG0745	RESPONSE REGULATOR receiver
Y89_3699	COG2205	protein histidine kinase activity
Y89_3704	COG1960	acyl-CoA dehydrogenase activity
Y89_3706	COG1024	Enoyl-CoA hydratase
Y89_3707	COG1250	3-hydroxyacyl-CoA dehydrogenase
Y89_3708	COG2186	Transcriptional regulator
Y89_3709	COG2807	transmembrane transport
Y89_3710	COG0628	permease
Y89_3712	COG0625	glutathione transferase activity
Y89_3718	COG1022	Amp-dependent synthetase and ligase
Y89_3724	COG0784	Response regulator, receiver
Y89_3724	COG2205	protein histidine kinase activity
Y89_3724	COG5002	protein histidine kinase activity
Y89_3732	COG1846	Transcriptional regulator
Y89_3733	COG2080	2 iron, 2 sulfur cluster binding
Y89_3734	COG2010	Cytochrome c
Y89_3734	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Y89_3735	COG2010	Cytochrome c
Y89_3735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Y89_3736	COG2207	Transcriptional regulator
Y89_3751	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Y89_3752	COG1053	succinate dehydrogenase
Y89_3753	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Y89_3754	COG2009	succinate dehydrogenase
Y89_3760	COG2084	Dehydrogenase
Y89_3763	COG3738	Protein conserved in bacteria
Y89_3768	COG0251	oxidation-reduction process
Y89_3769	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Y89_3770	COG0174	glutamine synthetase
Y89_3771	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Y89_3776	COG0840	transmembrane signaling receptor activity
Y89_3779	COG3278	Belongs to the heme-copper respiratory oxidase family
Y89_3782	COG2010	Cytochrome c
Y89_3783	COG3278	Belongs to the heme-copper respiratory oxidase family
Y89_3786	COG2010	Cytochrome c
Y89_3787	COG0348	domain, Protein
Y89_3789	COG2217	Heavy metal translocating P-type atpase
Y89_3797	COG2076	Multidrug Resistance protein
Y89_3803	COG1960	acyl-CoA dehydrogenase activity
Y89_3806	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Y89_3811	COG1196	nuclear chromosome segregation
Y89_3817	COG0402	S-adenosylhomocysteine deaminase activity
Y89_3819	COG2252	PERMEase
Y89_3827	COG3501	Rhs element vgr protein
Y89_3831	COG2233	PERMEase
Y89_3834	COG1309	transcriptional regulator
Y89_3836	COG3960	tartronate-semialdehyde synthase activity
Y89_3837	COG3622	Belongs to the hyi family
Y89_3838	COG2084	Dehydrogenase
Y89_3840	COG0469	pyruvate kinase activity
Y89_3841	COG4413	Urea transporter
Y89_3842	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Y89_3845	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Y89_3847	COG3192	ethanolamine utilization protein
Y89_3850	COG0446	pyridine nucleotide-disulphide oxidoreductase
Y89_3851	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Y89_3854	COG2197	response regulator
Y89_3866	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Y89_3869	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_3875	COG0835	chemotaxis
Y89_3877	COG1192	Involved in chromosome partitioning
Y89_3878	COG1360	Flagellar Motor Protein
Y89_3879	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Y89_3881	COG2198	Histidine kinase
Y89_3881	COG0643	Histidine kinase
Y89_3885	COG0455	bacterial-type flagellum organization
Y89_3887	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Y89_3888	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Y89_3892	COG1987	bacterial-type flagellum assembly
Y89_3900	COG2832	Protein of unknown function (DUF454)
Y89_3903	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y89_3904	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y89_3906	COG5001	Diguanylate cyclase
Y89_3906	COG3300	MHYT domain
Y89_3916	COG2350	Protein conserved in bacteria
Y89_3917	COG3485	protocatechuate 3,4-dioxygenase
Y89_3919	COG1012	belongs to the aldehyde dehydrogenase family
Y89_3922	COG0583	DNA-binding transcription factor activity
Y89_3936	COG0583	DNA-binding transcription factor activity
Y89_3939	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Y89_3941	COG1196	nuclear chromosome segregation
Y89_3941	COG3264	Mechanosensitive ion channel
Y89_3942	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Y89_3942	COG0116	Belongs to the methyltransferase superfamily
Y89_3944	COG0210	DNA helicase
Y89_3949	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Y89_3958	COG0438	transferase activity, transferring glycosyl groups
Y89_3960	COG0438	transferase activity, transferring glycosyl groups
Y89_3965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Y89_3967	COG1450	Type ii and iii secretion system protein
Y89_3969	COG2207	Transcriptional regulator
Y89_3970	COG4221	oxidoreductase activity
Y89_3972	COG1247	-acetyltransferase
Y89_3980	COG1733	regulation of RNA biosynthetic process
Y89_3981	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Y89_3983	COG0384	phenazine biosynthesis protein PhzF
Y89_3989	COG5006	permease, DMT superfamily
Y89_3992	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Y89_3995	COG3795	YCII-related domain
Y89_3997	COG2814	Major facilitator Superfamily
Y89_3998	COG4941	Belongs to the sigma-70 factor family
Y89_4001	COG3795	YCII-related domain
Y89_4003	COG2197	response regulator
Y89_4004	COG1982	Orn Lys Arg decarboxylase major
Y89_4005	COG0189	ligase activity
Y89_4006	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_4009	COG0765	amino acid transport
Y89_4010	COG0765	amino acid transport
Y89_4011	COG1126	abc transporter atp-binding protein
Y89_4016	COG1902	pentaerythritol trinitrate reductase activity
Y89_4019	COG1253	flavin adenine dinucleotide binding
Y89_4020	COG0300	oxidoreductase activity
Y89_4022	COG0583	DNA-binding transcription factor activity
Y89_4023	COG1864	DNA RNA non-specific endonuclease
Y89_4023	COG3591	Belongs to the peptidase S1B family
Y89_4024	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Y89_4025	COG4319	ketosteroid isomerase
Y89_4028	COG4774	siderophore transport
Y89_4037	COG2814	Major facilitator Superfamily
Y89_4041	COG0583	DNA-binding transcription factor activity
Y89_4043	COG0121	glutamine amidotransferase
Y89_4049	COG3712	iron ion homeostasis
Y89_4050	COG1595	DNA-templated transcription, initiation
Y89_4053	COG1230	cation diffusion facilitator family transporter
Y89_4054	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Y89_4066	COG1960	acyl-CoA dehydrogenase activity
Y89_4070	COG0406	alpha-ribazole phosphatase activity
Y89_4076	COG0778	Nitroreductase
Y89_4079	COG4206	TonB-dependent receptor
Y89_4081	COG1802	Transcriptional regulator
Y89_4083	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Y89_4089	COG0477	Major facilitator Superfamily
Y89_4093	COG0765	amino acid transport
Y89_4095	COG1126	abc transporter atp-binding protein
Y89_4097	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Y89_4098	COG1012	belongs to the aldehyde dehydrogenase family
Y89_4108	COG4191	Histidine kinase
Y89_4108	COG0784	Response regulator, receiver
Y89_4118	COG2207	Transcriptional regulator
Y89_4121	COG1289	transmembrane transporter activity
Y89_4124	COG2207	Transcriptional regulator
Y89_4128	COG2249	NAD(P)H dehydrogenase (quinone) activity
Y89_4129	COG2249	NAD(P)H dehydrogenase (quinone) activity
Y89_4131	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Y89_4136	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Y89_4138	COG0318	PFAM AMP-dependent synthetase and ligase
Y89_4139	COG0367	asparagine synthase
Y89_4141	COG2211	Major facilitator Superfamily
Y89_4151	COG1335	isochorismatase
Y89_4152	COG0583	DNA-binding transcription factor activity
Y89_4154	COG0791	NLP P60 protein
Y89_4155	COG0791	NLP P60 protein
Y89_4157	COG3829	transcription factor binding
Y89_4160	COG2818	Glycosylase
Y89_4165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Y89_4166	COG1960	acyl-CoA dehydrogenase activity
Y89_4168	COG0625	glutathione transferase activity
Y89_4172	COG5002	protein histidine kinase activity
Y89_4172	COG3447	MASE1 domain protein
Y89_4172	COG5001	Diguanylate cyclase
Y89_4174	COG0745	RESPONSE REGULATOR receiver
Y89_4176	COG4459	periplasmic nitrate reductase
Y89_4177	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
Y89_4177	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Y89_4178	COG3062	negative regulation of establishment of protein localization
Y89_4180	COG3043	anaerobic respiration
Y89_4181	COG3005	denitrification pathway
Y89_4182	COG2951	lytic endotransglycosylase activity
Y89_4183	COG0861	Integral membrane protein TerC family
Y89_4188	COG2977	Belongs to the P-Pant transferase superfamily
Y89_4189	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Y89_4192	COG2226	methyltransferase
Y89_4195	COG2205	protein histidine kinase activity
Y89_4196	COG0745	RESPONSE REGULATOR receiver
Y89_4197	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Y89_4197	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Y89_4198	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Y89_4199	COG1943	Transposase
Y89_4202	COG4104	PAAR repeat-containing protein
Y89_4205	COG0531	amino acid
Y89_4209	COG0560	Phosphoserine phosphatase
Y89_4211	COG0583	DNA-binding transcription factor activity
Y89_4212	COG3257	ureidoglycine aminohydrolase activity
Y89_4216	COG2197	response regulator
Y89_4224	COG0583	DNA-binding transcription factor activity
Y89_4225	COG0667	Aldo Keto reductase
Y89_4230	COG0242	peptide deformylase activity
Y89_4232	COG2199	diguanylate cyclase activity
Y89_4233	COG2885	chlorophyll binding
Y89_4239	COG1132	(ABC) transporter
Y89_4241	COG4628	conserved protein (DUF2132)
Y89_4242	COG2133	pyrroloquinoline quinone binding
Y89_4245	COG2207	Transcriptional regulator
Y89_4246	COG0477	Major facilitator Superfamily
Y89_4249	COG2882	bacterial-type flagellum organization
Y89_4255	COG2204	response regulator
Y89_4256	COG4191	Histidine kinase
Y89_4257	COG2204	response regulator
Y89_4261	COG1334	flagellar protein FlaG
Y89_4268	COG1256	bacterial-type flagellum assembly
Y89_4272	COG4786	Flagellar basal body rod
Y89_4273	COG4787	bacterial-type flagellum-dependent cell motility
Y89_4274	COG1749	Flagellar hook protein flgE
Y89_4275	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Y89_4276	COG1558	bacterial-type flagellum-dependent cell motility
Y89_4277	COG1815	bacterial-type flagellum-dependent cell motility
Y89_4286	COG0326	Molecular chaperone. Has ATPase activity
Y89_4289	COG3189	MarR family transcriptional regulator
Y89_4293	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Y89_4296	COG2212	antiporter activity
Y89_4298	COG0651	ATP synthesis coupled electron transport
Y89_4299	COG1006	Multisubunit Na H antiporter MnhC subunit
Y89_4300	COG2111	Na H antiporter
Y89_4300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Y89_4301	COG3133	Outer membrane lipoprotein
Y89_4303	COG1929	Belongs to the glycerate kinase type-1 family
Y89_4304	COG2610	gluconate transmembrane transporter activity
Y89_4305	COG3835	regulator
Y89_4307	COG2885	chlorophyll binding
Y89_4310	COG1199	ATP-dependent helicase activity
Y89_4318	COG2860	membrane
Y89_4322	COG0625	glutathione transferase activity
Y89_4327	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Y89_4328	COG1012	belongs to the aldehyde dehydrogenase family
Y89_4332	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_4333	COG1960	acyl-CoA dehydrogenase activity
Y89_4334	COG1024	Enoyl-CoA hydratase
Y89_4335	COG1960	acyl-CoA dehydrogenase activity
Y89_4337	COG2814	Major facilitator Superfamily
Y89_4338	COG2030	dehydratase
Y89_4345	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Y89_4346	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Y89_4349	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Y89_4351	COG0425	Belongs to the sulfur carrier protein TusA family
Y89_4352	COG4783	chaperone-mediated protein folding
Y89_4354	COG0583	DNA-binding transcription factor activity
Y89_4362	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Y89_4363	COG3188	usher protein
Y89_4370	COG2801	Transposase and inactivated derivatives
Y89_4371	COG2963	transposase activity
Y89_4373	COG2963	transposase activity
Y89_4380	COG0602	queuosine metabolic process
Y89_4381	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Y89_4387	COG0824	Thioesterase
Y89_4393	COG0783	Belongs to the Dps family
Y89_4403	COG3118	belongs to the thioredoxin family
Y89_4411	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Y89_4414	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Y89_4422	COG3122	Protein conserved in bacteria
Y89_4424	COG3956	TIGRFAM MazG family protein
Y89_4425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Y89_4431	COG2205	protein histidine kinase activity
Y89_4431	COG0784	Response regulator, receiver
Y89_4431	COG5002	protein histidine kinase activity
Y89_4432	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Y89_4441	COG3038	cytochrome b561
Y89_4444	COG4807	Protein conserved in bacteria
Y89_4446	COG2239	Acts as a magnesium transporter
Y89_4457	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
Y89_4470	COG4215	(ABC) transporter
Y89_4476	COG2301	Belongs to the HpcH HpaI aldolase family
Y89_4478	COG2079	MmgE PrpD family protein
Y89_4480	COG1960	acyl-CoA dehydrogenase activity
Y89_4481	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
Y89_4482	COG0583	DNA-binding transcription factor activity
Y89_4483	COG0583	DNA-binding transcription factor activity
Y89_4486	COG3283	Transcriptional regulator of aromatic amino acids metabolism
Y89_4493	COG1113	amino acid transport
Y89_4497	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_4497	COG0604	alcohol dehydrogenase
Y89_4497	COG3321	synthase
Y89_4499	COG5002	protein histidine kinase activity
Y89_4499	COG5001	Diguanylate cyclase
Y89_4500	COG1132	(ABC) transporter
Y89_4503	COG0271	Belongs to the BolA IbaG family
Y89_4511	COG0492	ferredoxin-NADP+ reductase activity
Y89_4512	COG0450	alkyl hydroperoxide reductase
Y89_4519	COG1307	EDD domain protein, DegV family
Y89_4521	COG1309	transcriptional regulator
Y89_4522	COG0386	Belongs to the glutathione peroxidase family
Y89_4526	COG0204	Acyl-transferase
Y89_4527	COG2885	chlorophyll binding
Y89_4528	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Y89_4531	COG2267	carboxylic ester hydrolase activity
Y89_4535	COG4974	Belongs to the 'phage' integrase family
Y89_4544	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Y89_4547	COG0546	phosphoglycolate phosphatase activity
Y89_4550	COG3023	N-Acetylmuramoyl-L-alanine amidase
Y89_4553	COG0656	L-ascorbic acid biosynthetic process
Y89_4558	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Y89_4560	COG1802	Transcriptional regulator
Y89_4562	COG0372	Belongs to the citrate synthase family
Y89_4565	COG2079	MmgE PrpD family protein
Y89_4568	COG1113	amino acid transport
Y89_4572	COG2076	Multidrug Resistance protein
Y89_4574	COG0583	DNA-binding transcription factor activity
Y89_4575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Y89_4577	COG4206	TonB-dependent receptor
Y89_4579	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Y89_4592	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Y89_4608	COG3180	Ammonia monooxygenase
Y89_4610	COG2720	vancomycin resistance protein
Y89_4613	COG1960	acyl-CoA dehydrogenase activity
Y89_4614	COG1024	Enoyl-CoA hydratase
Y89_4618	COG2910	NAD(P)H-binding
Y89_4619	COG2015	COG2015, Alkyl sulfatase and related hydrolases
Y89_4632	COG0582	viral genome integration into host DNA
Y89_4635	COG1192	Involved in chromosome partitioning
Y89_4642	COG0629	single-stranded DNA binding
Y89_4643	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Y89_4675	COG2003	Belongs to the UPF0758 family
Y89_4694	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Y89_4697	COG0459	protein refolding
Y89_4704	COG3316	Transposase and inactivated derivatives
Y89_4705	COG0789	Transcriptional regulator
Y89_4706	COG2608	mercury ion transmembrane transporter activity
Y89_4707	COG2608	mercury ion transmembrane transporter activity
Y89_4709	COG0789	Transcriptional regulator
Y89_4710	COG3316	Transposase and inactivated derivatives
Y89_4712	COG3586	endonuclease activity
Y89_4714	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Y89_4716	COG0583	DNA-binding transcription factor activity
Y89_4717	COG0464	growth
Y89_4725	COG0583	DNA-binding transcription factor activity
Y89_4728	COG0463	Glycosyl transferase, family 2
Y89_4729	COG0154	amidase activity
Y89_4730	COG0477	Major facilitator Superfamily
Y89_4733	COG0583	DNA-binding transcription factor activity
Y89_4735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Y89_4742	COG2831	hemolysin activation secretion protein
Y89_4765	COG0420	3'-5' exonuclease activity
Y89_4767	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Y89_4768	COG1074	ATP-dependent DNA helicase activity
Y89_4769	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Y89_4770	COG0095	Lipoate-protein ligase
Y89_4771	COG0697	spore germination
Y89_4774	COG0840	transmembrane signaling receptor activity
Y89_4776	COG0306	phosphate transporter
Y89_4780	COG4566	intracellular signal transduction
Y89_4788	COG4964	Belongs to the GSP D family
Y89_4792	COG0433	COG0433 Predicted ATPase
Y89_4799	COG0788	formyltetrahydrofolate deformylase activity
Y89_4801	COG2925	Exonuclease
Y89_4807	COG0714	Associated with various cellular activities
Y89_4813	COG0589	response to stress
Y89_4815	COG1024	Enoyl-CoA hydratase
Y89_4817	COG3706	GGDEF domain
Y89_4821	COG0693	protein deglycase activity
Y89_4824	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Y89_4827	COG0154	amidase activity
Y89_4829	COG1473	amidohydrolase
Y89_4832	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Y89_4833	COG0426	domain, Protein
Y89_4833	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Y89_4837	COG0589	response to stress
Y89_4840	COG2814	Major facilitator Superfamily
Y89_4841	COG1902	pentaerythritol trinitrate reductase activity
Y89_4844	COG1918	ferrous iron import across plasma membrane
Y89_4847	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Y89_4856	COG1704	LemA family
Y89_4861	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y89_4862	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y89_4865	COG3642	lipopolysaccharide core region biosynthetic process
Y89_4868	COG2205	protein histidine kinase activity
Y89_4869	COG0745	RESPONSE REGULATOR receiver
Y89_4876	COG3030	protein affecting phage T7 exclusion by the F plasmid
Y89_4878	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_4883	COG0668	transmembrane transport
Y89_4888	COG2096	Adenosyltransferase
Y89_4889	COG0494	nUDIX hydrolase
Y89_4893	COG0739	heme binding
Y89_4893	COG0741	lytic transglycosylase activity
Y89_4893	COG1196	nuclear chromosome segregation
Y89_4902	COG0772	Belongs to the SEDS family
Y89_4905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Y89_4912	COG3107	peptidoglycan biosynthetic process
Y89_4915	COG2823	Periplasmic or secreted lipoprotein
Y89_4916	COG2969	positive regulation of protein catabolic process
Y89_4917	COG0625	glutathione transferase activity
Y89_4918	COG2857	Cytochrome c1
Y89_4919	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Y89_4920	COG0723	plastoquinol--plastocyanin reductase activity
Y89_4923	COG0667	Aldo Keto reductase
Y89_4924	COG1960	acyl-CoA dehydrogenase activity
Y89_4927	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Y89_4929	COG2945	thiolester hydrolase activity
Y89_4933	COG2951	lytic endotransglycosylase activity
Y89_4935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Y89_4943	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Y89_4944	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Y89_4945	COG1127	ABC transporter
Y89_4948	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Y89_4951	COG1137	ATPase activity
Y89_4962	COG0312	modulator of DNA gyrase
Y89_4964	COG0312	modulator of DNA gyrase
Y89_4965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Y89_4967	COG1530	ribonuclease E activity
Y89_4970	COG1792	Involved in formation and maintenance of cell shape
Y89_4971	COG1077	Cell shape determining protein MreB Mrl
Y89_4975	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Y89_4976	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Y89_4977	COG4676	Protein conserved in bacteria
Y89_4978	COG5445	Predicted secreted protein (DUF2300)
Y89_4981	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
Y89_4982	COG4676	Protein conserved in bacteria
Y89_4983	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Y89_4986	COG0747	negative chemotaxis
Y89_4988	COG0747	negative chemotaxis
Y89_4989	COG0601	transmembrane transport
Y89_4990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Y89_4991	COG0444	Belongs to the ABC transporter superfamily
Y89_4992	COG4608	Belongs to the ABC transporter superfamily
Y89_4994	COG1522	sequence-specific DNA binding
Y89_4995	COG1984	allophanate hydrolase subunit 2
Y89_4999	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Y89_5000	COG4774	siderophore transport
Y89_5003	COG2194	sulfuric ester hydrolase activity
Y89_5005	COG0019	diaminopimelate decarboxylase activity
Y89_5011	COG0582	viral genome integration into host DNA
Y89_5023	COG2131	deaminase
Y89_5033	COG1987	bacterial-type flagellum assembly
Y89_5035	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Y89_5049	COG1252	NADH dehydrogenase
Y89_5050	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Y89_5053	COG1192	Involved in chromosome partitioning
Y89_5060	COG0305	Participates in initiation and elongation during chromosome replication
Y89_5079	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Y89_5082	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Y89_5083	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Y89_5088	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Y89_5116	COG1074	ATP-dependent DNA helicase activity
Y89_5138	COG3609	addiction module antidote protein, CC2985 family
Y89_5139	COG3668	Plasmid stabilization system
Y89_5144	COG4372	Transposase
Y89_5147	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Y89_5165	COG1047	Peptidyl-prolyl cis-trans
Y89_5168	COG0196	riboflavin kinase activity
Y89_5171	COG3045	CreA protein
Y89_5176	COG0142	geranyltranstransferase activity
Y89_5179	COG0545	Peptidyl-prolyl cis-trans isomerase
Y89_5183	COG1067	ATP-dependent peptidase activity
Y89_5188	COG4650	regulator
Y89_5190	COG1690	Belongs to the RtcB family
Y89_5191	COG3541	Predicted nucleotidyltransferase
Y89_5195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Y89_5200	COG1136	(ABC) transporter
Y89_5200	COG0577	efflux transmembrane transporter activity
Y89_5201	COG0577	efflux transmembrane transporter activity
Y89_5201	COG1136	(ABC) transporter
Y89_5202	COG0488	(ABC) transporter
Y89_5206	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y89_5207	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y89_5212	COG0523	cobalamin synthesis protein
Y89_5213	COG2879	small protein
Y89_5214	COG1966	Carbon starvation protein
Y89_5227	COG3608	succinylglutamate desuccinylase aspartoacylase
Y89_5227	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Y89_5228	COG2010	Cytochrome c
Y89_5235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Y89_5237	COG0833	amino acid
Y89_5238	COG2119	membrane
Y89_5241	COG0501	Belongs to the peptidase M48B family
Y89_5242	COG0840	transmembrane signaling receptor activity
Y89_5243	COG2135	peptidase activity
Y89_5244	COG1285	pathogenesis
Y89_5267	COG1090	epimerase
Y89_5268	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
Y89_5270	COG0789	Transcriptional regulator
Y89_5274	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Y89_5284	COG0012	GTP binding
Y89_5287	COG0288	reversible hydration of carbon dioxide
Y89_5289	COG0456	acetyltransferase
Y89_5298	COG1840	ABC-type Fe3 transport system, periplasmic component
Y89_5299	COG1178	ABC-type Fe3 transport system permease component
Y89_5300	COG3008	intermembrane lipid transfer
Y89_5301	COG2995	paraquat-inducible protein a
Y89_5302	COG2995	paraquat-inducible protein a
Y89_5305	COG1183	phosphatidylcholine synthase activity
Y89_5308	COG0028	Belongs to the TPP enzyme family
Y89_5310	COG3098	single-species biofilm formation
Y89_5312	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Y89_5319	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Y89_5320	COG4558	Periplasmic binding protein
Y89_5321	COG3720	iron ion transport
Y89_5322	COG4771	TonB-dependent receptor
Y89_5327	COG0436	Aminotransferase
Y89_5329	COG2321	neutral zinc metallopeptidase
Y89_5331	COG2252	PERMEase
Y89_5335	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Y89_5338	COG4191	Histidine kinase
Y89_5358	COG0195	Participates in both transcription termination and antitermination
Y89_5362	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Y89_5363	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Y89_5375	COG0497	DNA recombination
Y89_5381	COG2186	Transcriptional regulator
Y89_5382	COG1620	l-lactate permease
Y89_5388	COG0745	RESPONSE REGULATOR receiver
Y89_5392	COG0697	spore germination
Y89_5396	COG0697	spore germination
Y89_5397	COG1522	sequence-specific DNA binding
Y89_5399	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_5403	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Y89_5409	COG0509	glycine decarboxylation via glycine cleavage system
Y89_5416	COG0531	amino acid
Y89_5419	COG3276	selenocysteine insertion sequence binding
Y89_5422	COG2864	formate dehydrogenase
Y89_5423	COG0437	4 iron, 4 sulfur cluster binding
Y89_5426	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
Y89_5427	COG0446	pyridine nucleotide-disulphide oxidoreductase
Y89_5427	COG1902	pentaerythritol trinitrate reductase activity
Y89_5432	COG0463	Glycosyl transferase, family 2
Y89_5456	COG2369	cell adhesion
Y89_5458	COG4373	Mu-like prophage FluMu protein gp28
Y89_5476	COG0488	(ABC) transporter
Y89_5487	COG0463	Glycosyl transferase, family 2
Y89_5489	COG0534	Mate efflux family protein
Y89_5491	COG1283	sodium-dependent phosphate transmembrane transporter activity
Y89_5496	COG2162	N-hydroxyarylamine O-acetyltransferase activity
Y89_5501	COG4221	oxidoreductase activity
Y89_5502	COG1272	protein, Hemolysin III
Y89_5509	COG0023	Translation Initiation Factor
Y89_5526	COG2095	MarC family integral membrane protein
Y89_5527	COG0683	leucine binding
Y89_5528	COG0559	Belongs to the binding-protein-dependent transport system permease family
Y89_5530	COG0411	ABC transporter
Y89_5539	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Y89_5542	COG0443	Heat shock 70 kDa protein
Y89_5547	COG0789	Transcriptional regulator
Y89_5548	COG2982	Protein involved in outer membrane biogenesis
Y89_5549	COG2193	ferroxidase activity
Y89_5551	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Y89_5552	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
Y89_5564	COG3712	iron ion homeostasis
Y89_5565	COG1595	DNA-templated transcription, initiation
Y89_5572	COG0583	DNA-binding transcription factor activity
Y89_5577	COG4221	oxidoreductase activity
Y89_5578	COG2423	ornithine cyclodeaminase activity
Y89_5579	COG0410	ABC transporter
Y89_5582	COG0559	Belongs to the binding-protein-dependent transport system permease family
Y89_5584	COG0583	DNA-binding transcription factor activity
Y89_5587	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Y89_5595	COG0668	transmembrane transport
Y89_5599	COG5001	Diguanylate cyclase
Y89_5599	COG3300	MHYT domain
Y89_5601	COG0305	Participates in initiation and elongation during chromosome replication
Y89_5607	COG0557	exoribonuclease II activity
Y89_5611	COG0330	HflC and HflK could
Y89_5612	COG0330	HflC and HflK could
Y89_5613	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Y89_5617	COG0860	N-Acetylmuramoyl-L-alanine amidase
Y89_5618	COG0802	atpase or kinase
Y89_5619	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Y89_5619	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Y89_5629	COG5001	Diguanylate cyclase
Y89_5629	COG3300	MHYT domain
Y89_5630	COG3830	Belongs to the UPF0237 family
Y89_5630	COG0560	Phosphoserine phosphatase
Y89_5632	COG1988	membrane-bound metal-dependent
Y89_5635	COG3577	Aspartyl protease
Y89_5638	COG3150	esterase
Y89_5639	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Y89_5641	COG0494	nUDIX hydrolase
Y89_5644	COG1538	Outer membrane efflux protein
Y89_5645	COG2249	NAD(P)H dehydrogenase (quinone) activity
Y89_5648	COG0045	succinate-CoA ligase (ADP-forming) activity
Y89_5649	COG1960	acyl-CoA dehydrogenase activity
Y89_5650	COG1024	Enoyl-CoA hydratase
Y89_5651	COG0833	amino acid
Y89_5657	COG0446	pyridine nucleotide-disulphide oxidoreductase
Y89_5657	COG1902	pentaerythritol trinitrate reductase activity
Y89_5659	COG1519	Transferase
Y89_5660	COG0583	DNA-binding transcription factor activity
Y89_5663	COG0667	Aldo Keto reductase
Y89_5665	COG1960	acyl-CoA dehydrogenase activity
Y89_5666	COG1960	acyl-CoA dehydrogenase activity
Y89_5671	COG1215	transferase activity, transferring glycosyl groups
Y89_5676	COG0438	transferase activity, transferring glycosyl groups
Y89_5677	COG2192	nodulation
Y89_5682	COG0438	transferase activity, transferring glycosyl groups
Y89_5683	COG0859	PFAM glycosyl transferase family 9
Y89_5684	COG0859	PFAM glycosyl transferase family 9
Y89_5691	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Y89_5692	COG1960	acyl-CoA dehydrogenase activity
Y89_5694	COG1196	nuclear chromosome segregation
Y89_5694	COG3264	Mechanosensitive ion channel
Y89_5696	COG0730	response to heat
Y89_5697	COG2873	o-acetylhomoserine
Y89_5700	COG1192	Involved in chromosome partitioning
Y89_5701	COG0583	DNA-binding transcription factor activity
Y89_5702	COG2814	Major facilitator Superfamily
Y89_5707	COG0493	'glutamate synthase
Y89_5708	COG0067	glutamate synthase
Y89_5708	COG0069	glutamate synthase activity
Y89_5708	COG0070	glutamate synthase
Y89_5718	COG0281	malic enzyme
Y89_5722	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Y89_5744	COG0840	transmembrane signaling receptor activity
Y89_5746	COG1126	abc transporter atp-binding protein
Y89_5747	COG0765	amino acid transport
Y89_5753	COG1051	belongs to the nudix hydrolase family
Y89_5754	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y89_5755	COG0251	oxidation-reduction process
Y89_5760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Y89_5761	COG3501	Rhs element vgr protein
Y89_5764	COG2986	histidine ammonia-lyase
Y89_5766	COG4176	ABC-type proline glycine betaine transport system permease component
Y89_5770	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Y89_5777	COG0402	S-adenosylhomocysteine deaminase activity
Y89_5787	COG0789	Transcriptional regulator
Y89_5792	COG0668	transmembrane transport
Y89_5795	COG3852	Histidine kinase
Y89_5799	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Y89_5805	COG4942	peptidase
Y89_5806	COG0793	Belongs to the peptidase S41A family
Y89_5807	COG2861	carbohydrate metabolic process
Y89_5821	COG1194	a g-specific adenine glycosylase
Y89_5823	COG0673	inositol 2-dehydrogenase activity
Y89_5824	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_5831	COG1846	Transcriptional regulator
Y89_5833	COG1566	PFAM secretion protein HlyD family protein
Y89_5834	COG2814	Major facilitator Superfamily
Y89_5846	COG0582	viral genome integration into host DNA
Y89_5847	COG1088	dTDP-glucose 4,6-dehydratase activity
Y89_5848	COG1091	dTDP-4-dehydrorhamnose reductase activity
Y89_5861	COG1218	3'(2'),5'-bisphosphate nucleotidase
Y89_5862	COG0494	nUDIX hydrolase
Y89_5863	COG1011	Hydrolase
Y89_5864	COG1652	LysM domain
Y89_5866	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Y89_5870	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Y89_5872	COG0824	Thioesterase
Y89_5873	COG1454	alcohol dehydrogenase
Y89_5874	COG1960	acyl-CoA dehydrogenase activity
Y89_5875	COG1024	Enoyl-CoA hydratase
Y89_5875	COG1250	3-hydroxyacyl-CoA dehydrogenase
Y89_5877	COG0778	Nitroreductase
Y89_5882	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Y89_5883	COG4067	protein conserved in archaea
Y89_5883	COG0189	ligase activity
Y89_5886	COG2205	protein histidine kinase activity
Y89_5887	COG0745	RESPONSE REGULATOR receiver
Y89_5888	COG2183	response to ionizing radiation
Y89_5894	COG0306	phosphate transporter
Y89_5895	COG1392	Phosphate transport regulator
Y89_5896	COG3025	triphosphatase activity
Y89_5903	COG1178	ABC-type Fe3 transport system permease component
Y89_5905	COG0583	DNA-binding transcription factor activity
Y89_5908	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Y89_5910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Y89_5911	COG0006	proline dipeptidase activity
Y89_5915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Y89_5918	COG0842	Transport permease protein
Y89_5919	COG1129	ABC transporter
Y89_5919	COG0842	Transport permease protein
Y89_5920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y89_5923	COG2271	Major facilitator Superfamily
Y89_5926	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Y89_5926	COG2755	lipolytic protein G-D-S-L family
Y89_5929	COG0248	Ppx GppA phosphatase
Y89_5932	COG0586	Pfam SNARE associated Golgi protein
Y89_5933	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
Y89_5934	COG2050	protein possibly involved in aromatic compounds catabolism
Y89_5936	COG0672	)-iron permease
Y89_5937	COG1280	lysine exporter protein (LysE YggA)
Y89_5938	COG0861	Integral membrane protein TerC family
Y89_5940	COG0488	(ABC) transporter
Y89_5951	COG3275	phosphorelay sensor kinase activity
Y89_5955	COG3501	Rhs element vgr protein
Y89_5957	COG0598	Magnesium transport protein CorA
Y89_5961	COG3072	Adenylate cyclase
Y89_5963	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Y89_5975	COG0432	Pfam Uncharacterised protein family UPF0047
Y89_5976	COG0004	ammonium transporteR
Y89_5977	COG0347	Belongs to the P(II) protein family
Y89_5979	COG0606	chelatase, subunit chli
Y89_5984	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_5984	COG3321	synthase
Y89_5984	COG0604	alcohol dehydrogenase
Y89_5992	COG4221	oxidoreductase activity
Y89_5993	COG0583	DNA-binding transcription factor activity
Y89_5999	COG1902	pentaerythritol trinitrate reductase activity
Y89_6000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Y89_6009	COG0604	alcohol dehydrogenase
Y89_6010	COG1902	pentaerythritol trinitrate reductase activity
Y89_6022	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Y89_6028	COG0606	chelatase, subunit chli
Y89_6029	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Y89_6031	COG0583	DNA-binding transcription factor activity
Y89_6034	COG0210	DNA helicase
Y89_6035	COG0028	Belongs to the TPP enzyme family
Y89_6037	COG0427	acetyl-CoA hydrolase
Y89_6039	COG1917	Cupin 2, conserved barrel domain protein
Y89_6039	COG1396	sequence-specific DNA binding
Y89_6041	COG0251	oxidation-reduction process
Y89_6046	COG1522	sequence-specific DNA binding
Y89_6047	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Y89_6048	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Y89_6049	COG2814	Major facilitator Superfamily
Y89_6050	COG1012	belongs to the aldehyde dehydrogenase family
Y89_6055	COG0747	negative chemotaxis
Y89_6058	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Y89_6066	COG3245	cytochrome
Y89_6070	COG0708	Exodeoxyribonuclease III
Y89_6073	COG1561	YicC-like family, N-terminal region
Y89_6076	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Y89_6082	COG0583	DNA-binding transcription factor activity
Y89_6083	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Y89_6090	COG3193	protein, possibly involved in utilization of glycolate and propanediol
Y89_6091	COG0247	lactate metabolic process
Y89_6092	COG0277	FAD linked oxidase domain protein
Y89_6093	COG0277	FAD linked oxidase domain protein
Y89_6094	COG2186	Transcriptional regulator
Y89_6100	COG1253	flavin adenine dinucleotide binding
Y89_6101	COG0739	heme binding
Y89_6105	COG0573	inorganic phosphate transmembrane transporter activity
Y89_6108	COG0477	Major facilitator Superfamily
Y89_6109	COG1607	acyl-coa hydrolase
Y89_6113	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Y89_6114	COG4175	Glycine betaine
Y89_6115	COG4176	ABC-type proline glycine betaine transport system permease component
Y89_6117	COG1760	l-serine dehydratase
Y89_6120	COG0583	DNA-binding transcription factor activity
Y89_6125	COG3246	L-lysine catabolic process to acetate
Y89_6136	COG0446	pyridine nucleotide-disulphide oxidoreductase
Y89_6136	COG1902	pentaerythritol trinitrate reductase activity
Y89_6137	COG0247	lactate metabolic process
Y89_6137	COG2181	nitrate reductase activity
Y89_6141	COG3655	Transcriptional regulator
Y89_6150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Y89_6150	COG1017	nitric oxide dioxygenase activity
Y89_6167	COG0583	DNA-binding transcription factor activity
Y89_6169	COG2391	methyltransferase activity
Y89_6174	COG5016	pyruvate
Y89_6174	COG0511	ligase activity, forming carbon-carbon bonds
Y89_6175	COG0439	Biotin carboxylase
Y89_6176	COG0583	DNA-binding transcription factor activity
Y89_6179	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Y89_6184	COG0210	DNA helicase
Y89_6186	COG0427	acetyl-CoA hydrolase
Y89_6189	COG0438	transferase activity, transferring glycosyl groups
Y89_6198	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Y89_6199	COG2755	lipolytic protein G-D-S-L family
Y89_6199	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Y89_6207	COG0679	Auxin Efflux Carrier
Y89_6209	COG2851	Citrate transporter
Y89_6210	COG0861	Integral membrane protein TerC family
Y89_6211	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Y89_6212	COG1690	Belongs to the RtcB family
Y89_6219	COG0700	Nucleoside recognition
Y89_6220	COG1301	dicarboxylic acid transport
Y89_6224	COG5002	protein histidine kinase activity
Y89_6225	COG3023	N-Acetylmuramoyl-L-alanine amidase
Y89_6226	COG2095	MarC family integral membrane protein
Y89_6227	COG0745	RESPONSE REGULATOR receiver
Y89_6227	COG3706	GGDEF domain
Y89_6231	COG3245	cytochrome
Y89_6238	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Y89_6239	COG0735	belongs to the Fur family
Y89_6241	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Y89_6244	COG2011	ABC-type metal ion transport system permease component
Y89_6250	COG0531	amino acid
Y89_6252	COG4191	Histidine kinase
Y89_6258	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Y89_6258	COG4651	solute:proton antiporter activity
Y89_6259	COG1607	acyl-coa hydrolase
Y89_6261	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_6262	COG0174	glutamine synthetase
Y89_6263	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Y89_6264	COG1028	Short-chain dehydrogenase reductase Sdr
Y89_6269	COG4651	solute:proton antiporter activity
Y89_6269	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Y89_6270	COG0477	Major facilitator Superfamily
Y89_6272	COG0523	cobalamin synthesis protein
Y89_6276	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Y89_6281	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Y89_6286	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Y89_6287	COG0560	Phosphoserine phosphatase
Y89_6290	COG1349	DNA-binding transcription factor activity
Y89_6302	COG1475	DNA binding
Y89_6303	COG1192	Involved in chromosome partitioning
Y89_6316	COG3609	addiction module antidote protein, CC2985 family
Y89_6320	COG3328	transposase activity
Y89_6322	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Y89_6323	COG1192	Involved in chromosome partitioning
Y89_6330	COG0305	Participates in initiation and elongation during chromosome replication
Y89_6348	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Y89_6350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Y89_6351	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Y89_6356	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Y89_6386	COG1074	ATP-dependent DNA helicase activity