locus-tag	class	description
B2J77_00005	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
B2J77_00010	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
B2J77_00015	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
B2J77_00020	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
B2J77_00025	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
B2J77_00030	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
B2J77_00035	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
B2J77_00045	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
B2J77_00050	ENOG41064MJ	ATP synthase, subunit I
B2J77_00055	ENOG4105FA0	parb-like partition protein
B2J77_00060	ENOG4107QJE	Chromosome Partitioning Protein
B2J77_00065	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
B2J77_00070	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
B2J77_00075	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
B2J77_00080	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
B2J77_00085	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
B2J77_00090	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
B2J77_00095	ENOG4105VG0	50S ribosomal protein l34
B2J77_00100	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
B2J77_00105	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
B2J77_00110	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
B2J77_00115	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B2J77_00120	ENOG4105EMU	Dehydrogenase
B2J77_00125	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B2J77_00155	ENOG4105CSH	Transporter
B2J77_00165	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
B2J77_00170	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
B2J77_00175	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
B2J77_00180	ENOG4108R3E	Dna-3-methyladenine glycosylase i
B2J77_00190	ENOG4105WAP	TPR repeat-containing protein
B2J77_00195	ENOG4105C1A	potassium transporter peripheral membrane
B2J77_00200	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
B2J77_00205	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
B2J77_00210	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
B2J77_00215	ENOG4105C79	DNA protecting protein DprA
B2J77_00220	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
B2J77_00230	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
B2J77_00235	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
B2J77_00240	ENOG4105E2X	shikimate dehydrogenase
B2J77_00245	ENOG4105CHH	sulfate transporter
B2J77_00255	ENOG4105CBG	Sulfatase
B2J77_00270	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
B2J77_00275	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
B2J77_00290	ENOG4105WKW	Pfam:DUF1458
B2J77_00300	ENOG4105DEN	Luciferase family
B2J77_00305	ENOG4108Z9K	Osmotically inducible protein
B2J77_00310	ENOG4105KBG	Protein of unknown function (DUF1161)
B2J77_00330	ENOG4107XGZ	Hydrolase
B2J77_00335	ENOG4108Z0R	Transferase
B2J77_00340	ENOG4105DGW	oligopeptidase A
B2J77_00345	ENOG4105VKU	nucleicacid-binding protein
B2J77_00465	ENOG4107B2H	carbonic anhydrase
B2J77_00470	ENOG4105CHH	sulfate transporter
B2J77_00485	ENOG4105D01	(LipO)protein
B2J77_00490	ENOG4108UMI	ABC transporter, permease
B2J77_00495	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
B2J77_00510	ENOG4105FAV	ABC, transporter
B2J77_00515	ENOG4105FDK	ABC transporter
B2J77_00520	ENOG4105MYN	Zinc uptake regulation protein
B2J77_00525	ENOG4105NXV	High-affinity zinc uptake system protein
B2J77_00540	ENOG4105C2M	dna polymerase I
B2J77_00545	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
B2J77_00555	ENOG4106RE7	Cytochrome
B2J77_00560	ENOG4108Z33	Thiol disulfide Interchange Protein
B2J77_00570	ENOG4105BZU	Histidine kinase
B2J77_00575	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
B2J77_00580	ENOG41066DG	(EAL) domain protein
B2J77_00585	ENOG4105ES5	Histidine kinase
B2J77_00590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B2J77_00610	ENOG4108ZGU	inhibitor of vertebrate lysozyme
B2J77_00615	ENOG4105CK2	sodium dicarboxylate symporter
B2J77_00635	ENOG4105EAM	Na Pi-cotransporter
B2J77_00640	ENOG4105EE5	Membrane protein terC
B2J77_00645	ENOG4105D4T	Citrate transporter
B2J77_00675	ENOG4105CYC	Transferase
B2J77_00680	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
B2J77_00685	ENOG4105W8H	transhydrogenase (subunit alpha
B2J77_00690	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
B2J77_00695	ENOG4105ETT	transcriptional Regulator, LysR family
B2J77_00700	ENOG4105C1G	acyl-Coa dehydrogenase
B2J77_00705	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
B2J77_00765	ENOG4108SF5	RNA Polymerase
B2J77_00770	ENOG4105DRR	Transcriptional regulator, GntR family
B2J77_00780	ENOG4105BZU	Histidine kinase
B2J77_00805	ENOG4105E2B	Taurine dioxygenase
B2J77_00820	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
B2J77_00840	ENOG4105DSW	Fusaric acid resistance protein
B2J77_00850	ENOG4105Y49	secretion protein, HlyD family
B2J77_00870	ENOG4105IU3	Glutathione S-transferase
B2J77_00875	ENOG4105CH7	arginosuccinase
B2J77_00880	ENOG4108NEV	two component transcriptional regulator, LytTR family
B2J77_00885	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
B2J77_00890	ENOG41076E6	Uroporphyrinogen-III Synthase
B2J77_00910	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
B2J77_00930	ENOG4105C5H	ABC transporter
B2J77_00935	ENOG410829K	Lysine exporter protein (Lyse ygga)
B2J77_00985	ENOG4108594	Permease of the drug metabolite transporter
B2J77_01005	ENOG4105C26	Dehydrogenase
B2J77_01010	ENOG4108JPW	Aminotransferase
B2J77_01015	ENOG4105BZU	Histidine kinase
B2J77_01025	ENOG4105BZU	Histidine kinase
B2J77_01030	ENOG4108UMI	ABC transporter, permease
B2J77_01035	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
B2J77_01040	ENOG4105D01	(LipO)protein
B2J77_01055	ENOG4107T8P	acyl-Coa dehydrogenase
B2J77_01060	ENOG4105CDA	abc transporter atp-binding protein
B2J77_01065	ENOG4105E5Q	amino acid AbC transporter
B2J77_01070	ENOG4105EAB	amino acid AbC transporter
B2J77_01075	ENOG4105D7W	serine acetyltransferase
B2J77_01080	ENOG4105C94	Transporter
B2J77_01085	ENOG4105E2B	Taurine dioxygenase
B2J77_01090	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
B2J77_01095	ENOG4108IY8	ABC, transporter
B2J77_01100	ENOG4106FTQ	Taurine ABC transporter, periplasmic
B2J77_01105	ENOG4105J5J	Outer membrane porin
B2J77_01110	ENOG4105D3R	alkyl hydroperoxide reductase
B2J77_01115	ENOG4108UZX	fmn reductase
B2J77_01120	ENOG4105GVF	(ABC) transporter
B2J77_01125	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
B2J77_01130	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
B2J77_01135	ENOG4105E2Y	ABC, transporter
B2J77_01140	ENOG4105F4R	Transcriptional regulator mode
B2J77_01155	ENOG4105D9M	gamma-glutamylcysteine synthetase
B2J77_01165	ENOG4105BZM	domain protein
B2J77_01170	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
B2J77_01175	ENOG4105E0F	Histidine kinase
B2J77_01180	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
B2J77_01185	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
B2J77_01190	ENOG4105VEJ	Heat shock protein
B2J77_01200	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
B2J77_01205	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
B2J77_01220	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
B2J77_01225	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
B2J77_01230	ENOG4109066	lysm domain bon superfamily protein
B2J77_01235	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
B2J77_01240	ENOG4107RK2	ADP-ribose diphosphatase NudE
B2J77_01245	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
B2J77_01255	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B2J77_01260	ENOG4105CQZ	Histidine kinase
B2J77_01265	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
B2J77_01270	ENOG4105DWY	Agmatine deiminase
B2J77_01285	ENOG4105J5J	Outer membrane porin
B2J77_01290	ENOG4105E0F	Histidine kinase
B2J77_01295	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
B2J77_01300	ENOG4105CNM	Receptor
B2J77_01310	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
B2J77_01315	ENOG4108TQ9	Histidine kinase
B2J77_01360	ENOG4105DSP	amino acid AbC transporter
B2J77_01365	ENOG4105E89	ABC transporter
B2J77_01370	ENOG4108JEH	abc transporter atp-binding protein
B2J77_01385	ENOG4105CSR	polyphosphate kinase 2
B2J77_01395	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
B2J77_01400	ENOG4105CEN	a g-specific adenine glycosylase
B2J77_01410	ENOG4105FCD	Major Facilitator
B2J77_01415	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
B2J77_01420	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
B2J77_01430	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
B2J77_01435	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
B2J77_01440	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
B2J77_01445	ENOG4105C26	Dehydrogenase
B2J77_01450	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
B2J77_01455	ENOG4105C94	Transporter
B2J77_01485	ENOG4105PXI	polysaccharide deacetylase
B2J77_01490	ENOG4105CN1	protease
B2J77_01495	ENOG41063SB	peptidase
B2J77_01500	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
B2J77_01505	ENOG4107YZP	Rhodanese domain protein
B2J77_01510	ENOG4105VW4	glutaredoxin 3
B2J77_01515	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
B2J77_01520	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
B2J77_01530	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B2J77_01535	ENOG4105CUX	Signal transduction histidine kinase
B2J77_01550	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
B2J77_01580	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
B2J77_01585	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B2J77_01605	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
B2J77_01610	ENOG4105CZE	histidine utilization repressor
B2J77_01615	ENOG41090B9	response to stress
B2J77_01620	ENOG4105CGP	Urocanate hydratase
B2J77_01625	ENOG4105C84	Histidine ammonia-lyase
B2J77_01630	ENOG4105C85	amino acid
B2J77_01635	ENOG4105CI2	imidazolone-5-propionate hydrolase
B2J77_01650	ENOG4108HGY	Proline imino-peptidase
B2J77_01655	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
B2J77_01660	ENOG4105DJ9	glucan biosynthesis protein
B2J77_01665	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
B2J77_01670	ENOG4106PMH	Extracellular solute-binding protein family 3
B2J77_01675	ENOG4105EAD	ABC transporter
B2J77_01680	ENOG4105CDA	abc transporter atp-binding protein
B2J77_01690	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_01695	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_01710	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
B2J77_01715	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
B2J77_01720	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
B2J77_01725	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
B2J77_01730	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
B2J77_01740	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
B2J77_01765	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
B2J77_01770	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
B2J77_01775	ENOG4105CD3	dihydroorotase
B2J77_01780	ENOG4105CXT	aspartate transcarbamylase
B2J77_01785	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
B2J77_01790	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
B2J77_01795	ENOG4108UJU	UPF0301 protein
B2J77_01805	ENOG4105D7Z	glutathione synthase
B2J77_01810	ENOG4108UNF	response regulator
B2J77_01815	ENOG4105M3Z	response regulator
B2J77_01820	ENOG4108ZGA	chew protein
B2J77_01825	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_01830	ENOG4105CBS	Chea signal transduction histidine kinase
B2J77_01840	ENOG4108UT2	hemolysin iii
B2J77_01845	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
B2J77_01860	ENOG4105DS1	cytochrome b561
B2J77_01865	ENOG4108YYC	ycei family
B2J77_01870	ENOG4105C1J	atp-dependent rna helicase
B2J77_01880	ENOG4105SYT	Methylenetetrahydrofolate reductase
B2J77_01885	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
B2J77_01895	ENOG4105EEQ	Na H antiporter
B2J77_01925	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
B2J77_01930	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
B2J77_01935	ENOG41085FC	arsR family transcriptional regulator
B2J77_01945	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
B2J77_01950	ENOG4105BZA	Phosphoglycerate kinase
B2J77_01965	ENOG4105D2N	Aldolase
B2J77_01970	ENOG4105BZU	Histidine kinase
B2J77_01975	ENOG4108VKG	metal-dependent hydrolase
B2J77_01990	ENOG4105EM2	membrane
B2J77_01995	ENOG4105CBX	hi0933 family
B2J77_02000	ENOG4105C1J	atp-dependent rna helicase
B2J77_02005	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
B2J77_02020	ENOG4107NQ8	LysR family Transcriptional regulator
B2J77_02030	ENOG4105CSU	acyl-Coa dehydrogenase
B2J77_02035	ENOG4105C26	Dehydrogenase
B2J77_02040	ENOG4105CK7	Sodium proline symporter
B2J77_02045	ENOG4105D6S	protein involved in catabolism of external DNA
B2J77_02055	ENOG4105E2K	Glycosyl transferase (Group 1
B2J77_02075	ENOG4108SHN	Glycosyl transferase, family 2
B2J77_02095	ENOG4105BZ1	(ABC) transporter
B2J77_02100	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
B2J77_02110	ENOG4105CPC	Aldo Keto reductase
B2J77_02115	ENOG41087SS	fad dependent oxidoreductase
B2J77_02120	ENOG410814C	multidrug resistance protein
B2J77_02130	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
B2J77_02135	ENOG4105DFG	type I secretion outer membrane protein
B2J77_02140	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
B2J77_02155	ENOG41087AY	ADP-Ribose pyrophosphatase
B2J77_02165	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
B2J77_02170	ENOG4105IPS	esterase
B2J77_02175	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B2J77_02185	ENOG4108WIW	Aspartyl protease
B2J77_02190	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B2J77_02205	ENOG4105EAC	phosphoserine phosphatase
B2J77_02210	ENOG4105DJ4	phosphatidylserine decarboxylase
B2J77_02215	ENOG4105KHC	sulfurtransferase
B2J77_02225	ENOG4107RD7	Flagellar Motor Protein, MotA
B2J77_02230	ENOG4105ER2	Ompa motb domain protein
B2J77_02235	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
B2J77_02240	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
B2J77_02245	ENOG4105EN6	Membrane
B2J77_02250	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
B2J77_02255	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
B2J77_02260	ENOG4105K8N	protein family UPF0079, ATPase
B2J77_02265	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
B2J77_02270	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
B2J77_02275	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
B2J77_02280	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
B2J77_02285	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
B2J77_02290	ENOG4107QJR	hflk protein
B2J77_02295	ENOG4105EPW	hflc protein
B2J77_02300	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
B2J77_02305	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
B2J77_02310	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_02315	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
B2J77_02320	ENOG4107QKW	extracellular solute-binding protein family 1
B2J77_02335	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
B2J77_02340	ENOG4105C2N	RNA methyltransferase TrmH family group 3
B2J77_02345	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
B2J77_02350	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
B2J77_02360	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
B2J77_02365	ENOG4105CDU	Replicative dna helicase
B2J77_02370	ENOG4105CCT	upf0313 protein
B2J77_02380	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
B2J77_02385	ENOG4107RH7	Nicotinate phosphoribosyltransferase
B2J77_02395	ENOG4105C32	Amino acid ABC transporter (Permease)
B2J77_02400	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
B2J77_02405	ENOG4105C0Z	ABC transporter
B2J77_02410	ENOG4108IV0	ABC, transporter
B2J77_02415	ENOG4105EMU	Dehydrogenase
B2J77_02430	ENOG4105EJ2	Transcriptional regulator
B2J77_02445	ENOG41066T0	asmA family
B2J77_02460	ENOG4105VIF	phosphate starvation-inducible protein
B2J77_02470	ENOG4105R8A	Heat shock protein
B2J77_02475	ENOG4105DVC	DnaJ domain protein
B2J77_02480	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
B2J77_02485	ENOG4108Z7F	N-acetyltransferase
B2J77_02490	ENOG4108IV0	ABC, transporter
B2J77_02495	ENOG4105C0Z	ABC transporter
B2J77_02505	ENOG4105C32	Amino acid ABC transporter (Permease)
B2J77_02520	ENOG4105C85	amino acid
B2J77_02530	ENOG4107RNH	Outer membrane receptor FepA
B2J77_02550	ENOG4107QX8	SPFH domain, Band 7 family protein
B2J77_02565	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
B2J77_02570	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
B2J77_02575	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
B2J77_02580	ENOG41081F0	Precorrin-8x methylmutase
B2J77_02585	ENOG4105DVK	Precorrin-2 c20-methyltransferase
B2J77_02610	ENOG4105BZU	Histidine kinase
B2J77_02615	ENOG4105C12	Phosphoribosylglycinamide synthetase
B2J77_02620	ENOG4105DC1	bifunctional purine biosynthesis protein purh
B2J77_02625	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
B2J77_02630	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
B2J77_02640	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
B2J77_02655	ENOG41067MG	lrgb family
B2J77_02665	ENOG4108KF1	Membrane
B2J77_02670	ENOG4108RB4	3-methyladenine DNA glycosylase
B2J77_02675	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
B2J77_02680	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
B2J77_02690	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
B2J77_02695	ENOG4105CJN	penicillin-binding protein
B2J77_02700	ENOG4105CNI	cell division protein FtsW
B2J77_02705	ENOG4105CVE	Lytic murein transglycosylase
B2J77_02710	ENOG4105K6T	rare lipoprotein A
B2J77_02715	ENOG4105DZ1	carboxypeptidase
B2J77_02725	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
B2J77_02730	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
B2J77_02735	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
B2J77_02740	ENOG4105CVE	Lytic murein transglycosylase
B2J77_02760	ENOG4105C8T	Leucyl-tRNA synthetase
B2J77_02775	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
B2J77_02780	ENOG4108JU5	Magnesium and cobalt efflux protein
B2J77_02785	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
B2J77_02790	ENOG4105C9A	Phoh family
B2J77_02800	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
B2J77_02805	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
B2J77_02810	ENOG4105DWF	phosphomethylpyrimidine kinase
B2J77_02815	ENOG4105BZU	Histidine kinase
B2J77_02830	ENOG4105CSU	acyl-Coa dehydrogenase
B2J77_02835	ENOG4105FYV	Amp nucleosidase
B2J77_02840	ENOG4108R99	pseudouridine synthase
B2J77_02850	ENOG4108XM1	transcriptional regulator AsnC family
B2J77_02870	ENOG4105CQ7	ATP-dependent helicase
B2J77_02875	ENOG410829K	Lysine exporter protein (Lyse ygga)
B2J77_02880	ENOG4105CUB	amino acid
B2J77_02890	ENOG4105WH1	Two component transcriptional regulator luxr family
B2J77_02900	ENOG4105G4C	Periplasmic ligand-binding sensor protein
B2J77_02910	ENOG4105DVT	helicase
B2J77_02915	ENOG4105FDR	Membrane
B2J77_02920	ENOG4105C1J	atp-dependent rna helicase
B2J77_02930	ENOG4105DGU	Histone deacetylase
B2J77_02940	ENOG4108YYQ	gCN5-related N-acetyltransferase
B2J77_02945	ENOG4105C29	acyl-CoA thioesterase
B2J77_02955	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
B2J77_02965	ENOG4105EHG	Permease protein
B2J77_02970	ENOG4105E0A	ABC, transporter
B2J77_02980	ENOG4107MMM	Anti-sigma-factor antagonist
B2J77_02985	ENOG4105FUA	antagonist
B2J77_02990	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
B2J77_03000	ENOG4105BZU	Histidine kinase
B2J77_03010	ENOG4105E0K	tonB-dependent siderophore receptor
B2J77_03015	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
B2J77_03025	ENOG4108M9J	MaoC like domain protein
B2J77_03040	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
B2J77_03050	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
B2J77_03055	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
B2J77_03060	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
B2J77_03065	ENOG4105CH7	arginosuccinase
B2J77_03115	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
B2J77_03150	ENOG4105DKK	Benzoate
B2J77_03155	ENOG4105DFA	alanine racemase domain protein
B2J77_03160	ENOG4105C8Y	Acetylornithine aminotransferase
B2J77_03165	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
B2J77_03175	ENOG4105DMF	Dehydrogenase
B2J77_03180	ENOG4105DAA	L-lactate
B2J77_03185	ENOG41073TP	transcriptional regulator
B2J77_03190	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
B2J77_03195	ENOG4108Z1B	Cyclase dehydrase
B2J77_03200	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
B2J77_03205	ENOG41090R7	Ferric uptake
B2J77_03210	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
B2J77_03215	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B2J77_03220	ENOG4105CFG	Acts as a chaperone (By similarity)
B2J77_03225	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
B2J77_03230	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
B2J77_03235	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
B2J77_03240	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
B2J77_03245	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
B2J77_03255	ENOG4105HBR	Rna-binding protein
B2J77_03260	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
B2J77_03265	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
B2J77_03270	ENOG4105EEI	dihydropteroate synthase
B2J77_03275	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
B2J77_03280	ENOG4105CP7	Triose-phosphate isomerase
B2J77_03285	ENOG4105NTZ	Preprotein translocase subunit SecG
B2J77_03300	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
B2J77_03305	ENOG4105CHV	Transcription elongation factor NusA
B2J77_03315	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
B2J77_03320	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
B2J77_03325	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
B2J77_03330	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
B2J77_03335	ENOG4105W4M	Transport-associated protein
B2J77_03350	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
B2J77_03355	ENOG4107QP8	phosphohexose isomerase
B2J77_03360	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
B2J77_03365	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
B2J77_03370	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B2J77_03375	ENOG4105DJ0	Poly(A) Polymerase
B2J77_03385	ENOG4105BZU	Histidine kinase
B2J77_03395	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
B2J77_03400	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B2J77_03410	ENOG4105PW4	Sugar fermentation stimulation protein homolog
B2J77_03425	ENOG4105EHG	Permease protein
B2J77_03430	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
B2J77_03445	ENOG4105BZ4	penicillin-binding protein
B2J77_03455	ENOG4105WP7	tRNA pseudouridine synthase C
B2J77_03460	ENOG4105C7K	acetolactate synthase
B2J77_03465	ENOG4108ZP8	Acetolactate synthase small subunit
B2J77_03470	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
B2J77_03475	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
B2J77_03480	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
B2J77_03485	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
B2J77_03505	ENOG4105DSY	exodeoxyribonuclease V, gamma
B2J77_03510	ENOG4107QKA	exodeoxyribonuclease V beta
B2J77_03515	ENOG4107QYX	exodeoxyribonuclease v alpha
B2J77_03525	ENOG4105C26	Dehydrogenase
B2J77_03530	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
B2J77_03540	ENOG4108HPI	phosphatidate Cytidylyltransferase
B2J77_03555	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
B2J77_03560	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
B2J77_03565	ENOG4105DUM	transcriptional regulator, lysR family
B2J77_03580	ENOG4105NF4	modulator of drug activity
B2J77_03585	ENOG4105HEI	LysR family (Transcriptional regulator
B2J77_03590	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
B2J77_03595	ENOG4105DQ6	Transposase
B2J77_03600	ENOG4105IYK	transposase
B2J77_03605	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_03610	ENOG4105CGZ	zinc metallopeptidase
B2J77_03615	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
B2J77_03620	ENOG4105C7N	Xanthine uracil vitamin C permease
B2J77_03630	ENOG4105C4M	(Ubiquinol oxidase) subunit I
B2J77_03635	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
B2J77_03645	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
B2J77_03650	ENOG4105VJY	transcriptional regulator
B2J77_03655	ENOG4105DP0	ferredoxin-NADP reductase
B2J77_03660	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
B2J77_03665	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
B2J77_03670	ENOG4105C2W	permease
B2J77_03685	ENOG4105D22	carbon starvation protein
B2J77_03690	ENOG4105VCD	cytoplasmic protein
B2J77_03695	ENOG4105CKI	cobalamin synthesis protein
B2J77_03705	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
B2J77_03710	ENOG4105CHU	acetyl-coa acetyltransferase
B2J77_03715	ENOG4105RKW	reductase (By
B2J77_03745	ENOG4105BZU	Histidine kinase
B2J77_03750	ENOG4105QDK	Flavodoxin
B2J77_03765	ENOG4105F1J	Homogentisate 1,2-dioxygenase
B2J77_03775	ENOG4108RXX	maleylacetoacetate isomerase
B2J77_03785	ENOG41063JG	Transcriptional regulator
B2J77_03790	ENOG4107RDP	Dehydrogenase
B2J77_03840	ENOG4105E0K	tonB-dependent siderophore receptor
B2J77_03845	ENOG4105UEI	Transcriptional Regulator AraC Family
B2J77_03850	ENOG410631K	Membrane
B2J77_03855	ENOG4105C5I	Dehydrogenase
B2J77_03860	ENOG4105CR8	Transcriptional regulator
B2J77_03880	ENOG4105Y49	secretion protein, HlyD family
B2J77_03895	ENOG4107UWP	Major facilitator superfamily MFS_1
B2J77_03910	ENOG4105E1F	short-chain dehydrogenase reductase
B2J77_03935	ENOG4105D1Q	UPF0246 protein
B2J77_03945	ENOG4108IAB	Phoh family
B2J77_03950	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
B2J77_03955	ENOG4105M00	molybdopterin converting factor, subunit 1
B2J77_03960	ENOG4108ZAF	Molybdopterin
B2J77_03965	ENOG4105C1J	atp-dependent rna helicase
B2J77_03970	ENOG4106CJB	Phospholipase Carboxylesterase
B2J77_03980	ENOG4105EZ7	amino acid ABC transporter
B2J77_03985	ENOG4105DRP	amino acid AbC transporter
B2J77_03990	ENOG4105CDA	abc transporter atp-binding protein
B2J77_03995	ENOG4105C0H	protease
B2J77_04000	ENOG4107QNR	UPF0135 protein
B2J77_04005	ENOG4105C11	sulfate adenylyltransferase), subunit 2
B2J77_04010	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
B2J77_04020	ENOG4108XM1	transcriptional regulator AsnC family
B2J77_04040	ENOG4105C31	Tryptophanyl-tRNA synthetase
B2J77_04045	ENOG4105D6Z	AFG1 family ATPase
B2J77_04055	ENOG4105CPC	Aldo Keto reductase
B2J77_04060	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
B2J77_04065	ENOG4108UJD	30S ribosomal protein S9
B2J77_04070	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
B2J77_04075	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
B2J77_04080	ENOG4105EIX	cytochrome c1
B2J77_04085	ENOG4107MKT	Stringent starvation protein a
B2J77_04090	ENOG4105KB2	stringent starvation protein b
B2J77_04095	ENOG4105W4M	Transport-associated protein
B2J77_04100	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
B2J77_04105	ENOG41082RQ	UPF0102 protein
B2J77_04110	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
B2J77_04115	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
B2J77_04125	ENOG4108V6E	Cell division protein mraZ
B2J77_04130	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
B2J77_04140	ENOG4105CJN	penicillin-binding protein
B2J77_04145	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
B2J77_04150	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
B2J77_04155	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
B2J77_04160	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
B2J77_04165	ENOG4105CNI	cell division protein FtsW
B2J77_04170	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
B2J77_04175	ENOG4105DFU	Cell wall formation (By similarity)
B2J77_04180	ENOG4105CPF	Cell wall formation (By similarity)
B2J77_04185	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
B2J77_04190	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
B2J77_04195	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
B2J77_04200	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
B2J77_04210	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
B2J77_04215	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
B2J77_04220	ENOG4105M6F	mutator MutT protein
B2J77_04225	ENOG4108WBT	adenosyltransferase
B2J77_04230	ENOG4105BZU	Histidine kinase
B2J77_04235	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
B2J77_04240	ENOG4108VPT	UPF0234 protein
B2J77_04260	ENOG41080UX	Methyltransferase
B2J77_04280	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
B2J77_04285	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
B2J77_04300	ENOG4105DHQ	Histidine kinase
B2J77_04345	ENOG4105BZU	Histidine kinase
B2J77_04350	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
B2J77_04355	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
B2J77_04360	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
B2J77_04365	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
B2J77_04375	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
B2J77_04380	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
B2J77_04400	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
B2J77_04405	ENOG4107R7Y	intracellular protease Pfpi family
B2J77_04420	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
B2J77_04425	ENOG4107GFK	fumarate
B2J77_04430	ENOG4107QK7	reductase
B2J77_04435	ENOG4105CA9	Pyruvate kinase
B2J77_04450	ENOG4105CJB	Exodeoxyribonuclease I
B2J77_04480	ENOG4105BZF	Glycosyl transferase (Group 1
B2J77_04485	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_04490	ENOG4105D7A	ATP-binding protein
B2J77_04495	ENOG4105CJ3	phosphate transporter
B2J77_04510	ENOG4107HP6	Transcriptional regulator
B2J77_04515	ENOG4105CHU	acetyl-coa acetyltransferase
B2J77_04520	ENOG4105CSH	Transporter
B2J77_04530	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
B2J77_04540	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
B2J77_04545	ENOG4108IG5	Transcriptional regulator
B2J77_04550	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
B2J77_04555	ENOG4108JZP	Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate (By similarity)
B2J77_04560	ENOG4105EXG	Transcriptional regulator
B2J77_04570	ENOG4105CF7	AraC family transcriptional regulator
B2J77_04595	ENOG4105CSH	Transporter
B2J77_04600	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B2J77_04610	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
B2J77_04645	ENOG4105I08	Pseudouridine synthase
B2J77_04655	ENOG4105BZU	Histidine kinase
B2J77_04670	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
B2J77_04695	ENOG4105EPF	Outer membrane porin
B2J77_04720	ENOG4105Y75	tpr repeat protein
B2J77_04745	ENOG4105DQ6	Transposase
B2J77_04755	ENOG4108IYU	L-aspartate oxidase
B2J77_04760	ENOG4105EMN	RNA polymerase sigma factor
B2J77_04765	ENOG41069E1	anti sigma-E protein RseA
B2J77_04770	ENOG4105VQK	sigma E regulatory protein, MucB RseB
B2J77_04775	ENOG4105C0H	protease
B2J77_04780	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
B2J77_04785	ENOG4105C3F	Signal peptidase i
B2J77_04790	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
B2J77_04795	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
B2J77_04800	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
B2J77_04805	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
B2J77_04810	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
B2J77_04815	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
B2J77_04825	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
B2J77_04830	ENOG4105DZG	Dehydrogenase
B2J77_04835	ENOG4105TW1	Carbohydrate-selective porin OprB
B2J77_04840	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
B2J77_04845	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
B2J77_04855	ENOG4105Q26	Siderophore-interacting protein
B2J77_04860	ENOG4105NTW	Transcriptional regulator
B2J77_04870	ENOG4105CBC	glutamate synthase
B2J77_04875	ENOG4107QRT	dEAD DEAH box helicase
B2J77_04880	ENOG4105M6F	mutator MutT protein
B2J77_04885	ENOG4105DZ2	Transcriptional regulator
B2J77_04890	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B2J77_04895	ENOG4105CQZ	Histidine kinase
B2J77_04900	ENOG4105CDA	abc transporter atp-binding protein
B2J77_04905	ENOG4105DRP	amino acid AbC transporter
B2J77_04910	ENOG4105EAD	ABC transporter
B2J77_04915	ENOG4107RP9	extracellular solute-binding protein, family 3
B2J77_04930	ENOG4105E98	transcriptional regulator DeoR family
B2J77_04935	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
B2J77_04940	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
B2J77_04945	ENOG4108Z66	YbaK ebsC protein
B2J77_04950	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B2J77_04955	ENOG4105DBV	ornithine carbamoyltransferase
B2J77_04960	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
B2J77_04965	ENOG4105M2J	Glutaredoxin
B2J77_04970	ENOG4108UQY	Iron-storage protein
B2J77_04975	ENOG4105W53	bacterioferritin-associated ferredoxin
B2J77_04980	ENOG4105D3R	alkyl hydroperoxide reductase
B2J77_04985	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
B2J77_04990	ENOG4105EKE	dihydroorotase
B2J77_05000	ENOG4105CDH	Citrulline--aspartate ligase
B2J77_05010	ENOG4108WQH	regulatoR
B2J77_05020	ENOG4105CSM	endonuclease III
B2J77_05025	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
B2J77_05040	ENOG4105DHP	deoxycytidine triphosphate deaminase
B2J77_05055	ENOG4107QRT	dEAD DEAH box helicase
B2J77_05065	ENOG4107T0X	DNA ligase
B2J77_05070	ENOG4107T0X	DNA ligase
B2J77_05075	ENOG4105CUJ	penicillin amidase
B2J77_05085	ENOG4105DXI	Major Facilitator superfamily
B2J77_05090	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
B2J77_05100	ENOG4105K5B	UPF0225 protein
B2J77_05110	ENOG4105CDV	Ompa motb domain protein
B2J77_05130	ENOG4105DVT	helicase
B2J77_05145	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
B2J77_05150	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
B2J77_05165	ENOG4105DZ0	fad dependent oxidoreductase
B2J77_05175	ENOG4108IV0	ABC, transporter
B2J77_05180	ENOG4105C0Z	ABC transporter
B2J77_05185	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
B2J77_05190	ENOG4105C32	Amino acid ABC transporter (Permease)
B2J77_05195	ENOG4105CP9	extracellular ligand-binding receptor
B2J77_05210	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
B2J77_05215	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
B2J77_05245	ENOG4105BZU	Histidine kinase
B2J77_05250	ENOG4105S64	Formate nitrite transporter
B2J77_05285	ENOG4106RHG	Yeca family
B2J77_05300	ENOG4105EXG	Transcriptional regulator
B2J77_05375	ENOG4108WC9	type VI secretion system effector, hcp1 family
B2J77_05410	ENOG4105CSH	Transporter
B2J77_05415	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
B2J77_05420	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
B2J77_05430	ENOG4107EXC	regulatoR
B2J77_05435	ENOG4105JJR	Histidine kinase
B2J77_05455	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
B2J77_05465	ENOG4105CK2	sodium dicarboxylate symporter
B2J77_05470	ENOG4108R96	Methyltransferase, YaeB family
B2J77_05475	ENOG4108W15	Protein of unknown function (DUF1456)
B2J77_05485	ENOG4105K5X	acetyltransferase
B2J77_05490	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
B2J77_05495	ENOG4105DFH	Transport of potassium into the cell (By similarity)
B2J77_05525	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
B2J77_05535	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
B2J77_05540	ENOG4105J5J	Outer membrane porin
B2J77_05550	ENOG41069P5	Protein slyX homolog
B2J77_05555	ENOG4105VEQ	Cold shock protein
B2J77_05575	ENOG4105C9M	aspartyl-trna synthetase
B2J77_05580	ENOG4105CDY	transcriptional regulatory protein
B2J77_05585	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
B2J77_05590	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
B2J77_05595	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
B2J77_05600	ENOG4107YD3	Thioesterase
B2J77_05605	ENOG4105E02	MotA TolQ exbB proton channel
B2J77_05610	ENOG4105M8F	Biopolymer transport protein exbD tolR
B2J77_05620	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
B2J77_05625	ENOG4105KCK	Peptidoglycan-associated lipoprotein
B2J77_05630	ENOG4105UFD	tol-pal system protein YbgF
B2J77_05635	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
B2J77_05640	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
B2J77_05665	ENOG4107XTP	(EAL) domain protein
B2J77_05675	ENOG4105CUB	amino acid
B2J77_05690	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
B2J77_05695	ENOG4105ERG	peptidase m48, ste24p
B2J77_05700	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
B2J77_05710	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B2J77_05720	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
B2J77_05725	ENOG4105GJM	(LipO)protein
B2J77_05730	ENOG4105Q2H	domain protein
B2J77_05735	ENOG4105C8V	SAICAR synthetase
B2J77_05785	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
B2J77_05800	ENOG4105DWT	malate dehydrogenase (quinone)
B2J77_05805	ENOG4105YVS	arsR family transcriptional regulator
B2J77_05810	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
B2J77_05815	ENOG4105C5Q	Transcriptional regulator
B2J77_05820	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
B2J77_05830	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
B2J77_05840	ENOG4105CY0	Metallo-Beta-Lactamase
B2J77_05845	ENOG4105EXC	Acyl-transferase
B2J77_05855	ENOG4107QKV	phosphomannomutase
B2J77_05865	ENOG4105EY8	ABC transporter
B2J77_05875	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
B2J77_05895	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
B2J77_05905	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
B2J77_05930	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
B2J77_05960	ENOG4108JJ6	Type I secretion system ATPase
B2J77_05975	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
B2J77_05980	ENOG4108DMA	Nad-dependent epimerase dehydratase
B2J77_05985	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
B2J77_06000	ENOG4105ESV	Glycosyl transferase, family 4
B2J77_06010	ENOG4105IYK	transposase
B2J77_06015	ENOG4105DQ6	Transposase
B2J77_06020	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
B2J77_06030	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
B2J77_06035	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
B2J77_06045	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_06050	ENOG4105DKK	Benzoate
B2J77_06065	ENOG4105EUJ	GTP cyclohydrolase i
B2J77_06085	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
B2J77_06100	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
B2J77_06105	ENOG4105D8G	Major Facilitator superfamily
B2J77_06110	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
B2J77_06120	ENOG4105JXB	ankyrin repeat-containing protein
B2J77_06140	ENOG4105E0M	Sulfatase
B2J77_06160	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
B2J77_06165	ENOG4105D7N	magnesium and cobalt transport protein CorA
B2J77_06170	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
B2J77_06195	ENOG4105DND	Transcriptional regulator
B2J77_06215	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
B2J77_06220	ENOG4105K56	Transcriptional regulator
B2J77_06225	ENOG4105CC0	LysR family Transcriptional regulator
B2J77_06245	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
B2J77_06260	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
B2J77_06265	ENOG4105FQ6	thiopurine methyltransferase
B2J77_06270	ENOG4105D0M	Protease HtpX homolog
B2J77_06275	ENOG4105CHM	Aminotransferase
B2J77_06280	ENOG4105E0X	reductase
B2J77_06290	ENOG4105BZU	Histidine kinase
B2J77_06300	ENOG4108ZGC	gaf domain protein
B2J77_06345	ENOG4105CW0	outer membrane usher protein
B2J77_06380	ENOG4106UCC	Fimbrial protein
B2J77_06385	ENOG4108VCD	Chaperone
B2J77_06405	ENOG4107QPN	acyl-Coa dehydrogenase
B2J77_06410	ENOG4108TGY	Glutathione S-transferase
B2J77_06415	ENOG4105DA5	(ABC) transporter
B2J77_06420	ENOG4105E3A	(ABC) transporter
B2J77_06430	ENOG4108EC8	DNA internalization-related competence protein ComEC
B2J77_06440	ENOG4109015	Biopolymer transport protein exbD tolR
B2J77_06445	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
B2J77_06450	ENOG4105W49	UPF0434 protein
B2J77_06455	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
B2J77_06465	ENOG4105D4A	Cell wall formation (By similarity)
B2J77_06470	ENOG4105C03	ribonuclease
B2J77_06480	ENOG4105EI2	Pseudouridine synthase
B2J77_06485	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
B2J77_06490	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
B2J77_06495	ENOG4108UHJ	MAF-like protein
B2J77_06500	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
B2J77_06505	ENOG4105VGS	50s ribosomal protein l32
B2J77_06510	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
B2J77_06515	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
B2J77_06520	ENOG4105CHR	reductase
B2J77_06525	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
B2J77_06530	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
B2J77_06535	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
B2J77_06540	ENOG4105HHA	aminodeoxychorismate lyase
B2J77_06545	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
B2J77_06550	ENOG4107QRG	dna polymerase iii
B2J77_06555	ENOG4105F8V	Hydrolase, tatD family
B2J77_06565	ENOG4105DQ6	Transposase
B2J77_06610	ENOG4105CGF	Aromatic amino acid aminotransferase
B2J77_06615	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
B2J77_06620	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
B2J77_06660	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
B2J77_06670	ENOG4105BZU	Histidine kinase
B2J77_06675	ENOG4108MP6	LysR family Transcriptional regulator
B2J77_06680	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
B2J77_06685	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
B2J77_06690	ENOG4105F2W	methyltransferase
B2J77_06695	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
B2J77_06700	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
B2J77_06705	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
B2J77_06715	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
B2J77_06720	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
B2J77_06725	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
B2J77_06730	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
B2J77_06740	ENOG4105E96	Colicin v production protein
B2J77_06745	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
B2J77_06750	ENOG4105C28	cystathionine
B2J77_06755	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
B2J77_06785	ENOG4107QNJ	CoA-transferase subunit B
B2J77_06805	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
B2J77_06815	ENOG4105CPW	cytochrome b561
B2J77_06825	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
B2J77_06830	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
B2J77_06840	ENOG4105VUT	cytoplasmic protein
B2J77_06850	ENOG4105CD8	aminopeptidase N
B2J77_06870	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
B2J77_06880	ENOG4105EYH	Exonuclease
B2J77_06885	ENOG4107RH8	nuclease SbcCD subunit D
B2J77_06915	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
B2J77_06925	ENOG4107RTG	Major Facilitator superfamily
B2J77_06935	ENOG41067RQ	csbd family
B2J77_06940	ENOG4108Z4X	TRANSCRIPTIONal
B2J77_06945	ENOG4105FDP	GntR family transcriptional regulator
B2J77_06970	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
B2J77_06975	ENOG4105RQF	LysR family Transcriptional regulator
B2J77_06985	ENOG4105C7I	Dehydrogenase
B2J77_06990	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
B2J77_07005	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
B2J77_07030	ENOG4105CDV	Ompa motb domain protein
B2J77_07035	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
B2J77_07040	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
B2J77_07045	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
B2J77_07050	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
B2J77_07055	ENOG41090ED	Protein with unknown function (DUF469)
B2J77_07060	ENOG4105BZU	Histidine kinase
B2J77_07065	ENOG4108WQH	regulatoR
B2J77_07110	ENOG4105D3G	Pseudouridine synthase
B2J77_07115	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
B2J77_07120	ENOG4107QM5	aconitate hydratase
B2J77_07125	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
B2J77_07140	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
B2J77_07145	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
B2J77_07155	ENOG4105BZ1	(ABC) transporter
B2J77_07170	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
B2J77_07175	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
B2J77_07180	ENOG4107TE5	Lipid kinase
B2J77_07185	ENOG4105WH1	Two component transcriptional regulator luxr family
B2J77_07190	ENOG4105BZU	Histidine kinase
B2J77_07210	ENOG4107SC1	transglycosylase
B2J77_07215	ENOG4105C5H	ABC transporter
B2J77_07220	ENOG41081QV	Universal stress protein
B2J77_07230	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
B2J77_07245	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
B2J77_07260	ENOG4106AIJ	Cell Division
B2J77_07265	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
B2J77_07280	ENOG4105C0D	helicase
B2J77_07290	ENOG4108JA2	transcriptioN-repair coupling factor
B2J77_07300	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
B2J77_07305	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
B2J77_07315	ENOG4105D60	lipoprotein releasing system transmembrane protein
B2J77_07320	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
B2J77_07325	ENOG4105D60	lipoprotein releasing system transmembrane protein
B2J77_07345	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
B2J77_07365	ENOG4108ZXC	Two component transcriptional regulator, luxr family
B2J77_07380	ENOG4108T2C	cysteine dioxygenase type I
B2J77_07395	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
B2J77_07405	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B2J77_07410	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B2J77_07415	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
B2J77_07420	ENOG4105MP9	class II Aldolase
B2J77_07425	ENOG4108JQ1	Dehydrogenase
B2J77_07430	ENOG4105FDT	acyl-CoA dehydrogenase
B2J77_07435	ENOG4106KR7	LysR family Transcriptional regulator
B2J77_07445	ENOG4105GVF	(ABC) transporter
B2J77_07450	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
B2J77_07455	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
B2J77_07465	ENOG4105CDA	abc transporter atp-binding protein
B2J77_07475	ENOG4106IQC	argininosuccinate lyase
B2J77_07480	ENOG4105DRP	amino acid AbC transporter
B2J77_07485	ENOG4105E5Q	amino acid AbC transporter
B2J77_07490	ENOG4105CT1	(ABC) transporter
B2J77_07500	ENOG4105DHQ	Histidine kinase
B2J77_07505	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
B2J77_07515	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
B2J77_07565	ENOG4108IEG	Formate dehydrogenase Alpha subunit
B2J77_07575	ENOG4105Q9Y	Universal stress protein
B2J77_07580	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
B2J77_07600	ENOG4105WH9	RNA polymerase
B2J77_07615	ENOG4105D8V	Glucose sorbosone dehydrogenase
B2J77_07620	ENOG4105D6Z	AFG1 family ATPase
B2J77_07625	ENOG4105CPT	Alpha beta hydrolase
B2J77_07635	ENOG4105CFP	Peptidase U32
B2J77_07640	ENOG4108REF	Sporulation integral membrane protein ytvi
B2J77_07650	ENOG4108UQN	AraC family transcriptional regulator
B2J77_07670	ENOG4105CHU	acetyl-coa acetyltransferase
B2J77_07675	ENOG4105C1G	acyl-Coa dehydrogenase
B2J77_07680	ENOG4105E39	Enoyl-CoA hydratase
B2J77_07710	ENOG4107SDU	Methyl-accepting chemotaxis
B2J77_07715	ENOG4108JQ5	ABC transporter
B2J77_07720	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
B2J77_07725	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
B2J77_07735	ENOG4105E43	Extracellular solute-binding protein, family 5
B2J77_07740	ENOG4105E9H	Lytic Murein transglycosylase
B2J77_07745	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
B2J77_07755	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
B2J77_07760	ENOG4107RZZ	dna polymerase iii epsilon subunit
B2J77_07770	ENOG4108YYH	Nadph-dependent fmn reductase
B2J77_07805	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B2J77_07810	ENOG4105C8S	subunit m
B2J77_07815	ENOG4105D65	subunit l
B2J77_07820	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B2J77_07825	ENOG4107UFS	subunit j
B2J77_07830	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B2J77_07835	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
B2J77_07840	ENOG4107R0R	NADH dehydrogenase subunit g
B2J77_07845	ENOG4107QIZ	NADH dehydrogenase
B2J77_07850	ENOG4105GKE	subunit e
B2J77_07855	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B2J77_07860	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B2J77_07865	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B2J77_07895	ENOG4108I9X	Isocitrate lyase
B2J77_07910	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
B2J77_07915	ENOG4105CHH	sulfate transporter
B2J77_07930	ENOG4108JPW	Aminotransferase
B2J77_07935	ENOG4105C85	amino acid
B2J77_07960	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
B2J77_07980	ENOG4105CSV	Glutaminase
B2J77_07990	ENOG4105F04	LysR family Transcriptional regulator
B2J77_07995	ENOG4105C7F	AcnD-accessory protein PrpF
B2J77_08000	ENOG4105CK2	sodium dicarboxylate symporter
B2J77_08010	ENOG4105EPF	Outer membrane porin
B2J77_08035	ENOG4105CGU	Enoyl-CoA hydratase
B2J77_08040	ENOG4107QX3	carboxylase
B2J77_08045	ENOG4105C1G	acyl-Coa dehydrogenase
B2J77_08050	ENOG4105CEY	Amp-dependent synthetase and ligase
B2J77_08060	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
B2J77_08065	ENOG4105CG3	alpha amylase, catalytic region
B2J77_08070	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
B2J77_08090	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
B2J77_08100	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
B2J77_08105	ENOG4108J5G	6-phosphogluconate dehydrogenase
B2J77_08110	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
B2J77_08115	ENOG4105BZP	glycoside hydrolase 15-related
B2J77_08120	ENOG4108R86	Transcriptional regulator
B2J77_08125	ENOG4107SJI	Dehydrogenase
B2J77_08130	ENOG4105BZ8	glutamate synthase
B2J77_08135	ENOG4105CD3	dihydroorotase
B2J77_08140	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
B2J77_08145	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
B2J77_08150	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
B2J77_08155	ENOG4105QNF	Outer membrane lipoprotein
B2J77_08160	ENOG4105E39	Enoyl-CoA hydratase
B2J77_08165	ENOG4105E09	nadh pyrophosphatase
B2J77_08175	ENOG4105CFQ	glutamine synthetase
B2J77_08180	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
B2J77_08185	ENOG41082BV	acetyltransferase
B2J77_08190	ENOG4105EZE	Cupin 4 family protein
B2J77_08195	ENOG4107QTF	adenylosuccinate lyase
B2J77_08200	ENOG41075W9	High frequency lysogenization protein HflD homolog
B2J77_08205	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
B2J77_08215	ENOG4105E9K	Isocitrate dehydrogenase
B2J77_08220	ENOG4105VEQ	Cold shock protein
B2J77_08225	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
B2J77_08230	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
B2J77_08235	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
B2J77_08240	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
B2J77_08245	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
B2J77_08250	ENOG4105CNU	cell division protein FtsK
B2J77_08255	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
B2J77_08260	ENOG4105D1H	recombination factor protein RarA
B2J77_08265	ENOG4107N47	CrcB-like protein
B2J77_08270	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
B2J77_08275	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
B2J77_08280	ENOG4105EPF	Outer membrane porin
B2J77_08310	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
B2J77_08315	ENOG4105CHR	reductase
B2J77_08320	ENOG4107RSM	transcriptional regulator
B2J77_08325	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
B2J77_08330	ENOG4105CHR	reductase
B2J77_08335	ENOG4105CHF	Glutathione S-transferase
B2J77_08340	ENOG4108I0Q	anthranilate phosphoribosyltransferase
B2J77_08345	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
B2J77_08355	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
B2J77_08360	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
B2J77_08365	ENOG4105C2W	permease
B2J77_08370	ENOG4108MN8	Membrane
B2J77_08410	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
B2J77_08440	ENOG4108W9H	Tetr family transcriptional regulator
B2J77_08445	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
B2J77_08450	ENOG4108XHQ	(2Fe-2S)-binding domain protein
B2J77_08455	ENOG4108VHT	MarR family transcriptional regulator
B2J77_08465	ENOG4105MSY	salicylate hydroxylase
B2J77_08475	ENOG4105RE0	Asp Glu hydantoin racemase
B2J77_08480	ENOG4108UAU	isochorismatase
B2J77_08485	ENOG4105CSP	Major Facilitator Superfamily
B2J77_08490	ENOG4105EPF	Outer membrane porin
B2J77_08495	ENOG4105CNM	Receptor
B2J77_08500	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
B2J77_08520	ENOG4105BZU	Histidine kinase
B2J77_08525	ENOG4107QWE	)-transporter
B2J77_08540	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
B2J77_08545	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
B2J77_08565	ENOG4105ERU	peptidase
B2J77_08580	ENOG4105DUM	transcriptional regulator, lysR family
B2J77_08585	ENOG4105E32	cytoplasmic protein
B2J77_08590	ENOG4107RGD	Major Facilitator superfamily
B2J77_08600	ENOG4108RAV	Conserved protein
B2J77_08605	ENOG4105KT5	UmuD protein
B2J77_08610	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
B2J77_08615	ENOG4105FQR	PH-inducible protein involved in stress response
B2J77_08620	ENOG41065RR	hydrogen cyanide synthase HcnA
B2J77_08625	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
B2J77_08630	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
B2J77_08665	ENOG4105DQ4	alcohol dehydrogenase
B2J77_08680	ENOG4105CQZ	Histidine kinase
B2J77_08690	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
B2J77_08695	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
B2J77_08705	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
B2J77_08710	ENOG4105E0C	molybdate abc transporter
B2J77_08715	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
B2J77_08720	ENOG4107QWG	2-Nitropropane dioxygenase
B2J77_08740	ENOG41090Y2	cytochrome C
B2J77_08745	ENOG4105NQN	cytochrome C
B2J77_08750	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
B2J77_08755	ENOG4105DC8	reductase
B2J77_08760	ENOG4105D3R	alkyl hydroperoxide reductase
B2J77_08765	ENOG4108JU3	Alkyl hydroperoxide reductase
B2J77_08775	ENOG4108YXG	UPF0502 protein
B2J77_08780	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
B2J77_08785	ENOG41063Z6	transcriptional regulator, lysR family
B2J77_08795	ENOG4105EE5	Membrane protein terC
B2J77_08810	ENOG4105CJP	fad dependent oxidoreductase
B2J77_08840	ENOG4105CHB	tonB-dependent Receptor
B2J77_08845	ENOG4105HDK	L-asparaginase
B2J77_08850	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
B2J77_08855	ENOG4105C2J	ABC transporter
B2J77_08860	ENOG4105CNN	ABC, transporter
B2J77_08865	ENOG4105ETE	Transcriptional regulator (LacI family
B2J77_08870	ENOG4108RVA	ribokinase
B2J77_08875	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
B2J77_08905	ENOG4105C22	threonyL-tRNA synthetase
B2J77_08910	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
B2J77_08915	ENOG41082NX	50s ribosomal protein l35
B2J77_08920	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
B2J77_08925	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
B2J77_08930	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
B2J77_08935	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
B2J77_09035	ENOG41076J9	exonuclease VIII
B2J77_09065	ENOG4105RDA	repressor
B2J77_09260	ENOG4105WXW	Antirepressor
B2J77_09330	ENOG4105KT5	UmuD protein
B2J77_09340	ENOG4105CT1	(ABC) transporter
B2J77_09345	ENOG4105CDA	abc transporter atp-binding protein
B2J77_09350	ENOG4105E5Q	amino acid AbC transporter
B2J77_09355	ENOG4105E5Q	amino acid AbC transporter
B2J77_09370	ENOG4105CZQ	inner membrane transport protein YdhC
B2J77_09385	ENOG4107EJG	GntR family transcriptional regulator
B2J77_09405	ENOG4105CZJ	Aldehyde dehydrogenase
B2J77_09430	ENOG4105CPC	Aldo Keto reductase
B2J77_09475	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
B2J77_09480	ENOG4108Z6B	deaminase
B2J77_09485	ENOG4105DJ2	Major Facilitator Superfamily
B2J77_09500	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
B2J77_09505	ENOG4105EU8	FAD linked oxidase domain protein
B2J77_09525	ENOG4105CJN	penicillin-binding protein
B2J77_09535	ENOG4105C2I	pirin domain protein
B2J77_09555	ENOG4105DQ6	Transposase
B2J77_09565	ENOG41088T4	Helicase IV
B2J77_09570	ENOG4108J2P	Alpha beta hydrolase fold
B2J77_09580	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
B2J77_09585	ENOG4108YNN	Heme oxygenase
B2J77_09590	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
B2J77_09595	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
B2J77_09605	ENOG410642W	LysR family Transcriptional regulator
B2J77_09610	ENOG4105IJY	hydroxylase
B2J77_09615	ENOG4105FE1	phytoene synthase
B2J77_09620	ENOG4105EWK	phytoene
B2J77_09630	ENOG41087PP	glycosyltransferase MGT family
B2J77_09635	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
B2J77_09640	ENOG4108UK3	Polyprenyl synthetase
B2J77_09645	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B2J77_09655	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
B2J77_09665	ENOG4105G2Y	Transcriptional regulator
B2J77_09670	ENOG4105DY8	decarboxylase
B2J77_09690	ENOG4105JIM	Phosphatidylserine synthase
B2J77_09695	ENOG4105BZU	Histidine kinase
B2J77_09700	ENOG4105BZU	Histidine kinase
B2J77_09705	ENOG4105EWT	decarboxylase family
B2J77_09710	ENOG4105HMI	Membrane
B2J77_09715	ENOG4105DUM	transcriptional regulator, lysR family
B2J77_09725	ENOG4107RH7	Nicotinate phosphoribosyltransferase
B2J77_09740	ENOG4105CQZ	Histidine kinase
B2J77_09745	ENOG4105CQZ	Histidine kinase
B2J77_09750	ENOG4105E09	nadh pyrophosphatase
B2J77_09755	ENOG4108KWP	DNA-binding transcriptional regulator GlcC
B2J77_09760	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
B2J77_09770	ENOG4105C26	Dehydrogenase
B2J77_09775	ENOG4108MXF	Alpha Beta Hydrolase
B2J77_09785	ENOG4108M8W	Monooxygenase
B2J77_09790	ENOG4105MXW	flavin reductase domain protein, FMN-binding
B2J77_09795	ENOG4105ETS	cytosine purines uracil thiamine allantoin
B2J77_09820	ENOG4105D7T	ABC transporter
B2J77_09825	ENOG4105I5W	Transporter
B2J77_09830	ENOG4105DG7	nitrate ABC transporter
B2J77_09840	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
B2J77_09850	ENOG4106MWK	domain protein
B2J77_09860	ENOG4105C94	Transporter
B2J77_09890	ENOG4105DDY	UPF0142 protein ycaO
B2J77_09915	ENOG41066VF	YeeE YedE family protein
B2J77_09930	ENOG41073TP	transcriptional regulator
B2J77_09935	ENOG4105CZJ	Aldehyde dehydrogenase
B2J77_09940	ENOG4105CTX	dehydratase
B2J77_09945	ENOG4105DJB	Major Facilitator Superfamily
B2J77_09950	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
B2J77_09955	ENOG4108Z86	Glutamine amidotransferase
B2J77_09960	ENOG4105DG4	malate L-lactate dehydrogenase
B2J77_09965	ENOG4105CGF	Aromatic amino acid aminotransferase
B2J77_09970	ENOG4105C44	Serine transporter
B2J77_09975	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
B2J77_09980	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
B2J77_09995	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
B2J77_10000	ENOG4105BZU	Histidine kinase
B2J77_10020	ENOG4108SF5	RNA Polymerase
B2J77_10025	ENOG4108S3W	Anti-feci sigma factor, fecr
B2J77_10045	ENOG4108HQS	Glycine betaine
B2J77_10055	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_10060	ENOG4105D3Y	Na H antiporter
B2J77_10070	ENOG41067TZ	transcriptional regulator, MarR family
B2J77_10075	ENOG4105CW7	secretion protein, HlyD family
B2J77_10080	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
B2J77_10085	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
B2J77_10095	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B2J77_10100	ENOG4105C58	cytochrome c oxidase accessory protein ccog
B2J77_10110	ENOG4108302	MgtC SapB transporter
B2J77_10115	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
B2J77_10120	ENOG4108Z6Z	Transcriptional regulator
B2J77_10125	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
B2J77_10130	ENOG4105EGI	Transcriptional regulator
B2J77_10135	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
B2J77_10140	ENOG4105S0E	allantoin catabolism protein
B2J77_10150	ENOG4105GVF	(ABC) transporter
B2J77_10160	ENOG4105ECQ	AraC Family Transcriptional Regulator
B2J77_10185	ENOG4105CM2	brancheD-chain amino acid aminotransferase
B2J77_10190	ENOG4105C5H	ABC transporter
B2J77_10195	ENOG4107QRP	cobalamin biosynthesis protein CobW
B2J77_10200	ENOG4105CTK	cobaltochelatase, cobn subunit
B2J77_10220	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B2J77_10225	ENOG4105CFP	Peptidase U32
B2J77_10230	ENOG4105KME	endoribonuclease L-psp
B2J77_10240	ENOG4105EXG	Transcriptional regulator
B2J77_10245	ENOG4105C1G	acyl-Coa dehydrogenase
B2J77_10280	ENOG4105CSH	Transporter
B2J77_10290	ENOG4108R6K	riboflavin synthase, subunit alpha
B2J77_10315	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
B2J77_10335	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
B2J77_10340	ENOG4105CYM	Glutathione S-transferase
B2J77_10350	ENOG4105C5H	ABC transporter
B2J77_10370	ENOG4105CAU	Arsenical resistance protein, ArsH
B2J77_10375	ENOG4107WAU	Protein tyrosine phosphatase
B2J77_10385	ENOG41082YX	Transcriptional regulator, arsr family
B2J77_10400	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
B2J77_10405	ENOG4105K5X	acetyltransferase
B2J77_10475	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
B2J77_10490	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
B2J77_10515	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
B2J77_10520	ENOG4105DTD	Dehydrogenase
B2J77_10525	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
B2J77_10530	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
B2J77_10545	ENOG4108ISG	Major Facilitator
B2J77_10550	ENOG4105DQ6	Transposase
B2J77_10565	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
B2J77_10570	ENOG4105BZS	acriflavin resistance protein
B2J77_10575	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
B2J77_10580	ENOG4107EXC	regulatoR
B2J77_10585	ENOG4105JJR	Histidine kinase
B2J77_10595	ENOG4105C7B	Threonine dehydratase
B2J77_10605	ENOG4105C26	Dehydrogenase
B2J77_10635	ENOG4105EE5	Membrane protein terC
B2J77_10645	ENOG4105BZU	Histidine kinase
B2J77_10665	ENOG4105BZU	Histidine kinase
B2J77_10685	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
B2J77_10695	ENOG4105C6Z	Gluconate
B2J77_10700	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
B2J77_10705	ENOG4105ETE	Transcriptional regulator (LacI family
B2J77_10710	ENOG4105BZU	Histidine kinase
B2J77_10715	ENOG4108WQH	regulatoR
B2J77_10720	ENOG4105XDF	Protein of unknown function (DUF1272)
B2J77_10725	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
B2J77_10760	ENOG4105EUB	pirin domain protein
B2J77_10775	ENOG4105CF1	Alkylated DNA repair protein
B2J77_10795	ENOG4108M60	Transcriptional regulator
B2J77_10805	ENOG4105D7K	pfkb domain protein
B2J77_10810	ENOG4105DJB	Major Facilitator Superfamily
B2J77_10820	ENOG4105RWS	endonuclease I
B2J77_10825	ENOG4105CPC	Aldo Keto reductase
B2J77_10835	ENOG4105F27	Major Facilitator
B2J77_10840	ENOG4105DUM	transcriptional regulator, lysR family
B2J77_10845	ENOG4105C7K	acetolactate synthase
B2J77_10850	ENOG4105BZU	Histidine kinase
B2J77_10855	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
B2J77_10870	ENOG4107VMU	Membrane
B2J77_10910	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
B2J77_10915	ENOG4105SB3	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
B2J77_10950	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
B2J77_10980	ENOG4105BZU	Histidine kinase
B2J77_11000	ENOG4105BZU	Histidine kinase
B2J77_11005	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
B2J77_11020	ENOG4105X23	Endonuclease Exonuclease phosphatase
B2J77_11025	ENOG4105DZQ	phospholipase D Transphosphatidylase
B2J77_11030	ENOG4107UXM	Membrane
B2J77_11045	ENOG4105DQE	DNA ligase
B2J77_11070	ENOG4105FDF	Could be involved in DNA repair (By similarity)
B2J77_11080	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
B2J77_11115	ENOG4105IJY	hydroxylase
B2J77_11125	ENOG4106TD9	Diguanylate cyclase
B2J77_11150	ENOG4108SGR	YheO domain-containing protein
B2J77_11165	ENOG4105DZC	cytosine deaminase
B2J77_11170	ENOG4105ETU	transcriptional activator (TenA
B2J77_11180	ENOG4105BZU	Histidine kinase
B2J77_11190	ENOG4105BZW	Glycerate kinase
B2J77_11195	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
B2J77_11200	ENOG4105CSP	Major Facilitator Superfamily
B2J77_11205	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
B2J77_11210	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
B2J77_11215	ENOG4105C26	Dehydrogenase
B2J77_11255	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
B2J77_11260	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
B2J77_11290	ENOG41061N2	exported protein
B2J77_11295	ENOG4105EGI	Transcriptional regulator
B2J77_11300	ENOG4105C26	Dehydrogenase
B2J77_11305	ENOG4107QUV	Domain protein
B2J77_11315	ENOG4105CFQ	glutamine synthetase
B2J77_11320	ENOG4108HM4	ABC transporter
B2J77_11325	ENOG4105CJP	fad dependent oxidoreductase
B2J77_11335	ENOG4105EJQ	L-serine dehydratase
B2J77_11340	ENOG4105ETT	transcriptional Regulator, LysR family
B2J77_11345	ENOG4105D3Q	Sugar transferase
B2J77_11360	ENOG4107T8Q	Glycosyl transferase (Group 1
B2J77_11375	ENOG4105D7W	serine acetyltransferase
B2J77_11415	ENOG4105CMR	udp-glucose 4-epimerase
B2J77_11445	ENOG4105CRW	Short chain fatty acid transporter
B2J77_11455	ENOG4105D6N	CoA-transferase, subunit a
B2J77_11460	ENOG4105DUM	transcriptional regulator, lysR family
B2J77_11465	ENOG4105CV8	reductase
B2J77_11470	ENOG4105C0B	DNA polymerase III (alpha subunit)
B2J77_11485	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
B2J77_11490	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
B2J77_11520	ENOG4105DQ6	Transposase
B2J77_11535	ENOG4105C8N	cysteinyl-tRNA synthetase
B2J77_11540	ENOG4105CX6	glutaminyL-tRNA synthetase
B2J77_11550	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
B2J77_11555	ENOG4107SQI	penicillin amidase
B2J77_11595	ENOG4105CFU	surface antigen
B2J77_11605	ENOG4105CGK	Exodeoxyribonuclease III
B2J77_11615	ENOG4105EMN	RNA polymerase sigma factor
B2J77_11620	ENOG4107VGR	Catalase
B2J77_11625	ENOG4105CPW	cytochrome b561
B2J77_11630	ENOG4107VRI	Transcriptional regulator
B2J77_11635	ENOG4105DHU	Bile acid
B2J77_11655	ENOG4108594	Permease of the drug metabolite transporter
B2J77_11660	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
B2J77_11665	ENOG4105EXG	Transcriptional regulator
B2J77_11675	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
B2J77_11680	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_11730	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
B2J77_11735	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
B2J77_11745	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
B2J77_11750	ENOG4105CQM	Urea amidohydrolase subunit alpha
B2J77_11755	ENOG4105KI2	Urea amidohydrolase subunit beta
B2J77_11765	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
B2J77_11770	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
B2J77_11775	ENOG4105DVT	helicase
B2J77_11780	ENOG4105F2V	VRR-NUC domain-containing protein
B2J77_11835	ENOG4105E2S	oxidase) subunit II
B2J77_11840	ENOG4105BZ9	Cytochrome C oxidase, subunit I
B2J77_11845	ENOG4105CCU	oxidase (Subunit III)
B2J77_11850	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
B2J77_11855	ENOG4107SFI	Major Facilitator superfamily
B2J77_11860	ENOG4105JSC	dimethylmenaquinone methyltransferase
B2J77_11865	ENOG4108JQ1	Dehydrogenase
B2J77_11875	ENOG4105GAK	amidohydrolase 2
B2J77_11885	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
B2J77_11905	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
B2J77_11910	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
B2J77_11920	ENOG4105BZU	Histidine kinase
B2J77_11940	ENOG4105C26	Dehydrogenase
B2J77_11965	ENOG4105DZG	Dehydrogenase
B2J77_11985	ENOG4105ENE	Histidine kinase
B2J77_12000	ENOG4105CJ1	ABC, transporter
B2J77_12020	ENOG4105BZU	Histidine kinase
B2J77_12045	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
B2J77_12050	ENOG4105E2Z	phosphate ABC transporter (Permease
B2J77_12060	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
B2J77_12090	ENOG4105CQZ	Histidine kinase
B2J77_12095	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
B2J77_12100	ENOG4105E0F	Histidine kinase
B2J77_12105	ENOG4105E2A	Dehydrogenase
B2J77_12110	ENOG4105CQZ	Histidine kinase
B2J77_12125	ENOG4105CEV	competence damage-inducible protein
B2J77_12140	ENOG4105BZP	glycoside hydrolase 15-related
B2J77_12180	ENOG4105D64	Mechanosensitive ion channel
B2J77_12185	ENOG4105WEF	catalase
B2J77_12200	ENOG4105C54	Major Facilitator superfamily
B2J77_12215	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
B2J77_12220	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
B2J77_12225	ENOG4105C7W	Xanthine dehydrogenase
B2J77_12250	ENOG4105CHR	reductase
B2J77_12255	ENOG4105ETT	transcriptional Regulator, LysR family
B2J77_12260	ENOG4105BZ1	(ABC) transporter
B2J77_12285	ENOG4105F27	Major Facilitator
B2J77_12290	ENOG4105EQ2	LysR family Transcriptional regulator
B2J77_12295	ENOG4105CY0	Metallo-Beta-Lactamase
B2J77_12300	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B2J77_12305	ENOG4105T38	integral membrane protein
B2J77_12310	ENOG4105BZU	Histidine kinase
B2J77_12315	ENOG4105BZU	Histidine kinase
B2J77_12320	ENOG4107Z5C	methylesterase
B2J77_12325	ENOG4105BZU	Histidine kinase
B2J77_12330	ENOG4105BZU	Histidine kinase
B2J77_12355	ENOG4105F9E	Shikimate 5-dehydrogenase
B2J77_12365	ENOG4105BZU	Histidine kinase
B2J77_12380	ENOG41061WM	D-Alanyl-D-Alanine
B2J77_12390	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
B2J77_12420	ENOG4105FDK	ABC transporter
B2J77_12435	ENOG4107QS8	(LipO)protein
B2J77_12460	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
B2J77_12470	ENOG4105F38	ABC transporter, permease
B2J77_12475	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
B2J77_12480	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B2J77_12485	ENOG4107S17	Phosphate-binding protein
B2J77_12490	ENOG4105DU1	integral membrane protein, terc
B2J77_12520	ENOG4105C3J	Cysteine desulfurase
B2J77_12525	ENOG4108RCM	Nitroreductase
B2J77_12545	ENOG4105F27	Major Facilitator
B2J77_12555	ENOG4105DQ4	alcohol dehydrogenase
B2J77_12560	ENOG4105CF7	AraC family transcriptional regulator
B2J77_12590	ENOG4105EHG	Permease protein
B2J77_12595	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
B2J77_12615	ENOG4106TD9	Diguanylate cyclase
B2J77_12620	ENOG4105CSH	Transporter
B2J77_12635	ENOG4105CQ2	DNA polymerase
B2J77_12640	ENOG4105ETT	transcriptional Regulator, LysR family
B2J77_12690	ENOG4108ZX6	Electron transport protein SCO1 SenC
B2J77_12695	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
B2J77_12710	ENOG4105C3R	Methionine synthase
B2J77_12715	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
B2J77_12775	ENOG4105BZU	Histidine kinase
B2J77_12780	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
B2J77_12800	ENOG4105D6Z	AFG1 family ATPase
B2J77_12805	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
B2J77_12825	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
B2J77_12845	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
B2J77_12870	ENOG4107QIJ	Aconitate hydratase 2
B2J77_12875	ENOG4105C7F	AcnD-accessory protein PrpF
B2J77_12880	ENOG4108I0Z	Aconitate hydratase
B2J77_12885	ENOG4105BZN	citrate synthase
B2J77_12890	ENOG4105CR4	methylisocitrate lyase
B2J77_12895	ENOG4105DRR	Transcriptional regulator, GntR family
B2J77_12900	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
B2J77_12915	ENOG4105CRQ	synthase (Component I)
B2J77_12925	ENOG4107R11	Transcriptional regulator
B2J77_12935	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
B2J77_12940	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
B2J77_12955	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
B2J77_12965	ENOG4108UJV	acyl-CoA thioesterase i
B2J77_12970	ENOG4108I0Y	(ABC) transporter
B2J77_12975	ENOG4105CV6	ABC transporter, permease
B2J77_12980	ENOG4107YV3	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
B2J77_12995	ENOG4108IJ7	Glycine betaine
B2J77_13000	ENOG4107258	Transcriptional regulator
B2J77_13010	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
B2J77_13035	ENOG4108RRZ	Transcription elongation factor GreB
B2J77_13045	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
B2J77_13050	ENOG4105F8V	Hydrolase, tatD family
B2J77_13085	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
B2J77_13090	ENOG4105K70	DNA-binding protein
B2J77_13095	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
B2J77_13100	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
B2J77_13105	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
B2J77_13110	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
B2J77_13140	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
B2J77_13170	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_13175	ENOG4107TSN	permease
B2J77_13235	ENOG4108W2Y	isochorismatase
B2J77_13250	ENOG4105D65	subunit l
B2J77_13255	ENOG4108ZE9	Monovalent cation H antiporter subunit C
B2J77_13260	ENOG4107R4Z	monovalent cation h antiporter subunit d
B2J77_13270	ENOG4105W4C	monovalent cation H antiporter subunit F
B2J77_13275	ENOG4105KJM	monovalent cation h antiporter subunit g
B2J77_13290	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B2J77_13320	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
B2J77_13325	ENOG4105C08	Histidine kinase
B2J77_13330	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
B2J77_13335	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
B2J77_13340	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
B2J77_13350	ENOG4105IPI	Membrane
B2J77_13360	ENOG4108YIQ	Alpha beta hydrolase
B2J77_13375	ENOG4108BY2	phosphohistidine phosphatase
B2J77_13385	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
B2J77_13390	ENOG4107RNH	Outer membrane receptor FepA
B2J77_13400	ENOG4105BZU	Histidine kinase
B2J77_13405	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
B2J77_13425	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
B2J77_13440	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
B2J77_13445	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
B2J77_13450	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
B2J77_13455	ENOG4107QN2	dihydrolipoyl dehydrogenase
B2J77_13460	ENOG4105C7S	Dehydrogenase
B2J77_13465	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
B2J77_13470	ENOG4105E33	succinate dehydrogenase
B2J77_13475	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
B2J77_13480	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
B2J77_13485	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
B2J77_13490	ENOG4105BZN	citrate synthase
B2J77_13495	ENOG4105VV6	START domain-containing protein
B2J77_13510	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B2J77_13530	ENOG4105C10	Electron transfer flavoprotein
B2J77_13535	ENOG4105BZJ	Electron transfer flavoprotein
B2J77_13540	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
B2J77_13545	ENOG4105CSH	Transporter
B2J77_13560	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
B2J77_13565	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
B2J77_13595	ENOG4105IBP	Cyclic peptide transporter
B2J77_13645	ENOG4105DQ6	Transposase
B2J77_13650	ENOG4105DHQ	Histidine kinase
B2J77_13655	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
B2J77_13660	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
B2J77_13685	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
B2J77_13690	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B2J77_13695	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
B2J77_13730	ENOG4108M15	ABC transporter
B2J77_13760	ENOG4105NBK	UPF0345 protein
B2J77_13770	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
B2J77_13785	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
B2J77_13795	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
B2J77_13810	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
B2J77_13815	ENOG4105C58	cytochrome c oxidase accessory protein ccog
B2J77_13825	ENOG4105C59	p-type ATPase
B2J77_13840	ENOG4105D4P	Coproporphyrinogen iii oxidase
B2J77_13850	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
B2J77_13855	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
B2J77_13860	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
B2J77_13865	ENOG4107QMP	dna polymerase iii subunits gamma and tau
B2J77_13880	ENOG4108Z6Z	Transcriptional regulator
B2J77_13890	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
B2J77_13895	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
B2J77_13915	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
B2J77_13925	ENOG4107QUY	Guanine deaminase
B2J77_13935	ENOG4105C7N	Xanthine uracil vitamin C permease
B2J77_13945	ENOG4105VT2	5-hydroxyisourate hydrolase
B2J77_13960	ENOG4108Z2U	ureidoglycolate hydrolase
B2J77_13970	ENOG4105C2W	permease
B2J77_13975	ENOG4105DRB	nucleoside-specific channel-forming protein
B2J77_13985	ENOG4105CKW	Inner membrane protein yedI
B2J77_13990	ENOG4105C7K	acetolactate synthase
B2J77_13995	ENOG41062JF	Transcriptional regulator
B2J77_14005	ENOG41060W2	glyoxylate carboligase
B2J77_14010	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
B2J77_14015	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
B2J77_14025	ENOG4105CA9	Pyruvate kinase
B2J77_14035	ENOG4105EYW	Ion transport protein
B2J77_14040	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
B2J77_14050	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
B2J77_14060	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
B2J77_14075	ENOG4105JAB	phenazine biosynthesis protein, phzf family
B2J77_14080	ENOG4105C5I	Dehydrogenase
B2J77_14090	ENOG4108M1T	Cytochrome c-type biogenesis protein
B2J77_14095	ENOG4105KWW	Biogenesis protein
B2J77_14105	ENOG4105DA4	cytochrome c-type biogenesis protein
B2J77_14110	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
B2J77_14120	ENOG41060IM	Heme exporter protein
B2J77_14125	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
B2J77_14130	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
B2J77_14140	ENOG4105VM1	flagellar
B2J77_14155	ENOG4108V3W	Chemotaxis protein, CheW
B2J77_14165	ENOG4107QJE	Chromosome Partitioning Protein
B2J77_14170	ENOG4105ER2	Ompa motb domain protein
B2J77_14175	ENOG4105E14	MotA TolQ exbB proton channel
B2J77_14180	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
B2J77_14185	ENOG4105CBS	Chea signal transduction histidine kinase
B2J77_14190	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
B2J77_14195	ENOG4108VYJ	response regulator receiver protein
B2J77_14200	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B2J77_14210	ENOG4105FZW	flagellar biosynthesis regulator FlhF
B2J77_14215	ENOG4105D7B	Flagellar biosynthesis protein flha
B2J77_14220	ENOG4105D00	flagellar biosynthetic protein flhB
B2J77_14225	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
B2J77_14230	ENOG4105VS8	Flagellar biosynthetic protein fliq
B2J77_14235	ENOG4105CN7	Flagellar biosynthetic protein FliP
B2J77_14240	ENOG4105VTB	flagellar biosynthesis protein fliO
B2J77_14245	ENOG4105DD5	Flagellar motor switch protein
B2J77_14250	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
B2J77_14270	ENOG4108KXV	response regulator
B2J77_14280	ENOG4105GSA	Flagellar export protein flij
B2J77_14285	ENOG4108JIR	Flagellum-specific ATP synthase
B2J77_14295	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
B2J77_14300	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
B2J77_14305	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
B2J77_14310	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B2J77_14315	ENOG4105BZU	Histidine kinase
B2J77_14320	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B2J77_14330	ENOG4105MQ3	flagellar protein FliS
B2J77_14335	ENOG4105DTS	flagellar hook-associated
B2J77_14340	ENOG41063QE	flagellar protein FlaG
B2J77_14345	ENOG4105I03	Flagellin
B2J77_14350	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
B2J77_14360	ENOG4105E1Q	flagellar hook-associated protein
B2J77_14365	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
B2J77_14370	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
B2J77_14375	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
B2J77_14380	ENOG4105CGA	flagellar basal-body rod protein FlgG
B2J77_14385	ENOG4108KPB	Flagellar basal-body rod protein FlgF
B2J77_14395	ENOG4105BZE	flagellar hook protein, FlgE
B2J77_14400	ENOG4105W00	Flagellar hook capping protein
B2J77_14405	ENOG4108ZC9	flagellar basal-body rod protein flgc
B2J77_14410	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
B2J77_14415	ENOG4105BZU	Histidine kinase
B2J77_14420	ENOG4107R88	Chemotaxis protein (CheV)
B2J77_14440	ENOG4106825	Type iv pilus assembly
B2J77_14450	ENOG4108ISG	Major Facilitator
B2J77_14455	ENOG4108YXU	transcriptional regulator AsnC family
B2J77_14460	ENOG4107R0V	Pyruvate dehydrogenase
B2J77_14465	ENOG4105CPP	Dehydrogenase, E1 component
B2J77_14470	ENOG4107QSN	dihydrolipoamide acetyltransferase
B2J77_14475	ENOG4107QN2	dihydrolipoyl dehydrogenase
B2J77_14480	ENOG4105BZU	Histidine kinase
B2J77_14490	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
B2J77_14500	ENOG4105CJW	magnesium transporter
B2J77_14530	ENOG4105CFH	Aspartokinase
B2J77_14535	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
B2J77_14560	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
B2J77_14565	ENOG4105C26	Dehydrogenase
B2J77_14570	ENOG4105F4X	arginine
B2J77_14575	ENOG4108T2Z	Arginine
B2J77_14580	ENOG4105C8Y	Acetylornithine aminotransferase
B2J77_14585	ENOG4105ECQ	AraC Family Transcriptional Regulator
B2J77_14590	ENOG4108JEH	abc transporter atp-binding protein
B2J77_14600	ENOG4105DSP	amino acid AbC transporter
B2J77_14605	ENOG4105E89	ABC transporter
B2J77_14610	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
B2J77_14620	ENOG4108JU8	Transcriptional regulator
B2J77_14625	ENOG4105MIR	Phenylalanine 4-monooxygenase
B2J77_14630	ENOG41090A4	Pterin carbinolamine dehydratase
B2J77_14640	ENOG4105CQB	FAD linked oxidase domain protein
B2J77_14645	ENOG4108MGI	Transcriptional regulator
B2J77_14650	ENOG4105C85	amino acid
B2J77_14655	ENOG4105FE9	pseudouridine synthase
B2J77_14660	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
B2J77_14665	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
B2J77_14670	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
B2J77_14675	ENOG4105DB7	PHP domain protein
B2J77_14680	ENOG4107835	probably involved in intracellular septation (By similarity)
B2J77_14685	ENOG4105K9H	YciI-like protein
B2J77_14690	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
B2J77_14700	ENOG410804D	Sensor Signal Transduction Histidine Kinase
B2J77_14705	ENOG41069NU	Nitroreductase
B2J77_14710	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
B2J77_14715	ENOG4108ZX5	transcriptional regulator
B2J77_14735	ENOG4105C9U	ATP-dependent DNA helicase RecQ
B2J77_14750	ENOG4105WD1	Membrane
B2J77_14765	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
B2J77_14770	ENOG4108Q5Y	Membrane
B2J77_14785	ENOG4105C1J	atp-dependent rna helicase
B2J77_14790	ENOG4105CUY	Mechanosensitive ion channel
B2J77_14800	ENOG4105RK9	auxin efflux carrier
B2J77_14805	ENOG4105EMK	carboxylate amino acid amine transporter
B2J77_14810	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
B2J77_14815	ENOG4105CAT	Cytidine monophosphate kinase
B2J77_14820	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
B2J77_14825	ENOG4105CQC	Prephenate dehydratase
B2J77_14830	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
B2J77_14835	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B2J77_14845	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
B2J77_14850	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
B2J77_14855	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
B2J77_14860	ENOG4105UBK	short-chain dehydrogenase reductase
B2J77_14870	ENOG4105BZU	Histidine kinase
B2J77_14885	ENOG4105D4T	Citrate transporter
B2J77_14890	ENOG4105DND	Transcriptional regulator
B2J77_14905	ENOG4105C72	UPF0176 protein
B2J77_14910	ENOG4105M85	Bola protein
B2J77_14920	ENOG4105C9Q	fumarate hydratase class II
B2J77_14925	ENOG4105QYV	Membrane
B2J77_14930	ENOG4105CSR	polyphosphate kinase 2
B2J77_14935	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
B2J77_14950	ENOG4105EHG	Permease protein
B2J77_14960	ENOG4105E0A	ABC, transporter
B2J77_14965	ENOG4105E0K	tonB-dependent siderophore receptor
B2J77_14975	ENOG4105CAQ	asparagine synthetase
B2J77_14980	ENOG4107RRY	Cyanophycin synthetase
B2J77_14985	ENOG4105DER	m42 family
B2J77_14990	ENOG4106851	UPF0270 protein
B2J77_15010	ENOG4107QN1	sodium solute
B2J77_15015	ENOG41062QD	Membrane
B2J77_15025	ENOG4105DQ6	Transposase
B2J77_15045	ENOG4105CFQ	glutamine synthetase
B2J77_15050	ENOG4105CJP	fad dependent oxidoreductase
B2J77_15055	ENOG4105CEY	Amp-dependent synthetase and ligase
B2J77_15060	ENOG4105CEY	Amp-dependent synthetase and ligase
B2J77_15065	ENOG4108Z7G	MaoC domain protein dehydratase
B2J77_15075	ENOG4107U9T	Pfam:Ribonuclease_BN
B2J77_15115	ENOG4105C6T	cysteine synthase
B2J77_15125	ENOG4108JUA	Transcriptional regulator
B2J77_15135	ENOG4107R7A	Allophanate hydrolase subunit 2
B2J77_15140	ENOG4105P4J	Allophanate hydrolase, subunit 1
B2J77_15145	ENOG4105E7W	lamb ycsf family protein
B2J77_15150	ENOG4107RGD	Major Facilitator superfamily
B2J77_15155	ENOG4105GZI	Transcriptional regulator
B2J77_15165	ENOG4105E7A	Glutamine amidotransferase
B2J77_15185	ENOG4105N1F	Hnh endonuclease
B2J77_15205	ENOG4108ZZ3	UPF0260 protein
B2J77_15210	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
B2J77_15215	ENOG4105VNG	YcgL domain-containing protein
B2J77_15225	ENOG4105DIJ	Phosphoethanolamine transferase
B2J77_15235	ENOG4105C28	cystathionine
B2J77_15240	ENOG4108XM1	transcriptional regulator AsnC family
B2J77_15250	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
B2J77_15255	ENOG4105FFC	UPF0187 protein
B2J77_15260	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
B2J77_15275	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
B2J77_15280	ENOG4105BZ1	(ABC) transporter
B2J77_15305	ENOG4105CQ7	ATP-dependent helicase
B2J77_15330	ENOG410903C	(LipO)protein
B2J77_15335	ENOG4105D1S	lipid A biosynthesis
B2J77_15340	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
B2J77_15345	ENOG4107QMS	site-determining protein
B2J77_15350	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
B2J77_15355	ENOG4105D3G	Pseudouridine synthase
B2J77_15360	ENOG4105DFM	M18 family aminopeptidase
B2J77_15370	ENOG4105D8X	mechanosensitive ion channel
B2J77_15385	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
B2J77_15390	ENOG4105F38	ABC transporter, permease
B2J77_15415	ENOG4105CN1	protease
B2J77_15435	ENOG4108V1T	peptidylprolyl cis-trans isomerase
B2J77_15465	ENOG4105DH7	May be involved in recombination (By similarity)
B2J77_15470	ENOG4105C09	Bile acid
B2J77_15475	ENOG4105KPY	Small multidrug resistance protein
B2J77_15485	ENOG4105GAK	amidohydrolase 2
B2J77_15490	ENOG4107RGD	Major Facilitator superfamily
B2J77_15495	ENOG4105FDP	GntR family transcriptional regulator
B2J77_15500	ENOG4105BZU	Histidine kinase
B2J77_15505	ENOG4105CGY	Dna recombination protein
B2J77_15525	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
B2J77_15530	ENOG4105EJC	lysr family transcriptional regulator
B2J77_15580	ENOG4105GN9	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
B2J77_15585	ENOG4108TGR	phosphatase
B2J77_15590	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
B2J77_15595	ENOG4108YZT	Adenosylcobinamide kinase
B2J77_15600	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
B2J77_15605	ENOG4105EFT	decarboxylase
B2J77_15610	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
B2J77_15615	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
B2J77_15620	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
B2J77_15625	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
B2J77_15635	ENOG4105K4H	Nlp p60 protein
B2J77_15645	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
B2J77_15650	ENOG4105C02	permease
B2J77_15660	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
B2J77_15665	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
B2J77_15680	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
B2J77_15685	ENOG4105DXN	mazG family
B2J77_15690	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
B2J77_15695	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
B2J77_15700	ENOG4105C6T	cysteine synthase
B2J77_15705	ENOG4105BZU	Histidine kinase
B2J77_15710	ENOG4105C5I	Dehydrogenase
B2J77_15725	ENOG4105K63	Thioredoxin
B2J77_15730	ENOG4105K89	arsenate reductase
B2J77_15735	ENOG4105CS1	NAD(P)H quinone oxidoreductase
B2J77_15750	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
B2J77_15755	ENOG4105GPY	SprT protein
B2J77_15760	ENOG4105DP0	ferredoxin-NADP reductase
B2J77_15765	ENOG4105DUM	transcriptional regulator, lysR family
B2J77_15770	ENOG41080IJ	Diacylglycerol kinase
B2J77_15780	ENOG4106IUH	DTW domain containing protein
B2J77_15795	ENOG4105Y3E	Modulates RecA activity (By similarity)
B2J77_15800	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
B2J77_15805	ENOG4107TH8	cina domain protein
B2J77_15810	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
B2J77_15815	ENOG4108Z4U	Ferredoxin
B2J77_15820	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B2J77_15825	ENOG4108K5P	(LipO)protein
B2J77_15830	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
B2J77_15835	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
B2J77_15840	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
B2J77_15845	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
B2J77_15860	ENOG4105EXG	Transcriptional regulator
B2J77_15865	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
B2J77_15870	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
B2J77_15875	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
B2J77_15880	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
B2J77_15885	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
B2J77_15895	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
B2J77_15900	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
B2J77_15905	ENOG4105C0B	DNA polymerase III (alpha subunit)
B2J77_15910	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
B2J77_15915	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
B2J77_15920	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
B2J77_15925	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
B2J77_15930	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
B2J77_15935	ENOG4105X4K	outer membrane chaperone skp
B2J77_15945	ENOG4105DZP	Membrane-associated zinc metalloprotease
B2J77_15950	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
B2J77_15955	ENOG4105KNE	Phosphatidate cytidylyltransferase
B2J77_15960	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
B2J77_15965	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
B2J77_15970	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
B2J77_15975	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
B2J77_15980	ENOG4105CE9	30S ribosomal protein S2
B2J77_15985	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
B2J77_15990	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
B2J77_15995	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
B2J77_16000	ENOG4105EEQ	Na H antiporter
B2J77_16005	ENOG4105KUZ	arsenate reductase
B2J77_16010	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
B2J77_16015	ENOG4105C9B	Cysteine desulfurase
B2J77_16020	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
B2J77_16025	ENOG4105CUZ	uba thif-type nad fad binding protein
B2J77_16030	ENOG4107QZ7	Cellulose synthase catalytic subunit
B2J77_16035	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
B2J77_16040	ENOG4105DHI	Methyltransferase
B2J77_16050	ENOG4105VEQ	Cold shock protein
B2J77_16055	ENOG4105E55	glycerol-3-phosphate acyltransferase
B2J77_16085	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
B2J77_16105	ENOG41081XQ	Conserved Protein
B2J77_16115	ENOG41072GX	Peptidase M22 Glycoprotease
B2J77_16120	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
B2J77_16125	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
B2J77_16140	ENOG4108ZG0	Ompa motb domain protein
B2J77_16150	ENOG4107XM9	(LipO)protein
B2J77_16170	ENOG4105CRK	lysyL-tRNA synthetase
B2J77_16185	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
B2J77_16190	ENOG4105CBS	Chea signal transduction histidine kinase
B2J77_16200	ENOG4108KTQ	Methyltransferase
B2J77_16220	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
B2J77_16225	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
B2J77_16230	ENOG4108VWS	Yaeq family
B2J77_16235	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
B2J77_16255	ENOG4105D98	threonine synthase
B2J77_16260	ENOG4105D6E	homoserine dehydrogenase
B2J77_16265	ENOG4105T95	Thiol disulfide interChange protein
B2J77_16270	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
B2J77_16280	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
B2J77_16285	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
B2J77_16290	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
B2J77_16295	ENOG4105K5M	30s ribosomal protein S16
B2J77_16300	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B2J77_16310	ENOG4108JU6	CBS domain protein
B2J77_16315	ENOG4105CSH	Transporter
B2J77_16320	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
B2J77_16335	ENOG4108Z0R	Transferase
B2J77_16350	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
B2J77_16355	ENOG4108I4D	hemolysin
B2J77_16395	ENOG4108ETH	Formylglycinamide ribotide synthetase
B2J77_16400	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
B2J77_16405	ENOG4108Z6B	deaminase
B2J77_16440	ENOG4105BZU	Histidine kinase
B2J77_16445	ENOG4105CBN	LysR family transcriptional regulator
B2J77_16450	ENOG41061H0	Monooxygenase
B2J77_16455	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_16460	ENOG4105CBN	LysR family transcriptional regulator
B2J77_16465	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
B2J77_16475	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
B2J77_16480	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
B2J77_16500	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
B2J77_16505	ENOG4105DR5	peptidase
B2J77_16515	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
B2J77_16520	ENOG4108UHU	Aldolase
B2J77_16530	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
B2J77_16535	ENOG4106KNT	transcriptional regulator
B2J77_16540	ENOG4105DSB	aldose 1-epimerase
B2J77_16545	ENOG4105TW1	Carbohydrate-selective porin OprB
B2J77_16550	ENOG4108IJ9	(ABC) transporter
B2J77_16560	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
B2J77_16570	ENOG4107QKS	N-acylglucosamine 2-epimerase
B2J77_16575	ENOG4105E0F	Histidine kinase
B2J77_16580	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
B2J77_16590	ENOG4105C01	Dihydroxy-acid dehydratase
B2J77_16595	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
B2J77_16600	ENOG4105DU6	RNA polymerase
B2J77_16610	ENOG4107ENK	receptor
B2J77_16615	ENOG4108YNN	Heme oxygenase
B2J77_16625	ENOG4105D5Q	Arginine ornithine antiporter
B2J77_16630	ENOG4105D5Q	Arginine ornithine antiporter
B2J77_16635	ENOG4105CEU	Arginine dihydrolase
B2J77_16640	ENOG4105DBV	ornithine carbamoyltransferase
B2J77_16645	ENOG4105C5B	carbamate kinase
B2J77_16660	ENOG4105D6U	Sodium Glutamate Symporter
B2J77_16670	ENOG4108MA7	Inherit from COG: YD repeat protein
B2J77_16675	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
B2J77_16680	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B2J77_16685	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
B2J77_16700	ENOG4108K5H	permease YjgP YjgQ family protein
B2J77_16705	ENOG4108M8S	permease YjgP YjgQ family protein
B2J77_16715	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
B2J77_16720	ENOG4105MYG	DNA polymerase iii, chi subunit
B2J77_16730	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
B2J77_16735	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
B2J77_16745	ENOG4106V8H	Nucleoid-associated protein
B2J77_16750	ENOG41082IR	Excinuclease ABC C subunit domain protein
B2J77_16765	ENOG4105DJ2	Major Facilitator Superfamily
B2J77_16770	ENOG4105CIH	Imidazole acetol-phosphate transaminase
B2J77_16775	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
B2J77_16780	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
B2J77_16785	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
B2J77_16805	ENOG4107PE3	Mammalian cell entry related domain protein
B2J77_16810	ENOG4105CY3	ABC transporter, permease
B2J77_16815	ENOG4105DHJ	ABC, transporter
B2J77_16820	ENOG4105C2X	Arabinose 5-phosphate isomerase
B2J77_16825	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
B2J77_16835	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
B2J77_16840	ENOG4108IUZ	ABC transporter
B2J77_16845	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B2J77_16850	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
B2J77_16855	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
B2J77_16860	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
B2J77_16875	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
B2J77_16885	ENOG4105C9Q	fumarate hydratase class II
B2J77_16895	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
B2J77_16900	ENOG4105N42	UPF0307 protein
B2J77_16905	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
B2J77_16920	ENOG4105C03	ribonuclease
B2J77_16925	ENOG4108Z03	MAF-like protein
B2J77_16935	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
B2J77_16940	ENOG4105DFF	Rod shape-determining protein mreb
B2J77_16945	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
B2J77_16950	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
B2J77_16955	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
B2J77_16970	ENOG4105C85	amino acid
B2J77_16985	ENOG4105TX3	Histidine kinase
B2J77_16995	ENOG4105DEF	Extracellular solute-binding protein, family 5
B2J77_17000	ENOG4105DEF	Extracellular solute-binding protein, family 5
B2J77_17005	ENOG4105J5J	Outer membrane porin
B2J77_17010	ENOG4105DEF	Extracellular solute-binding protein, family 5
B2J77_17015	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B2J77_17020	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B2J77_17025	ENOG4105C3U	ABC transporter
B2J77_17030	ENOG4108JQ7	(ABC) transporter
B2J77_17040	ENOG4108DMH	HTH_ARAC
B2J77_17045	ENOG4105CJP	fad dependent oxidoreductase
B2J77_17055	ENOG4108HM4	ABC transporter
B2J77_17060	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
B2J77_17070	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
B2J77_17075	ENOG4105E90	ABC transporter
B2J77_17080	ENOG4108IJ8	ABC transporter
B2J77_17085	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
B2J77_17090	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
B2J77_17095	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
B2J77_17100	ENOG4105CHM	Aminotransferase
B2J77_17110	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
B2J77_17115	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
B2J77_17125	ENOG4105CUT	histidyl-tRNA synthetase
B2J77_17130	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
B2J77_17145	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
B2J77_17150	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
B2J77_17155	ENOG4105WVQ	Fe-S assembly protein IscX
B2J77_17160	ENOG4108ZIT	Ferredoxin, 2FE-2S
B2J77_17165	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
B2J77_17170	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
B2J77_17175	ENOG4108Z4V	iron-sulfur cluster assembly
B2J77_17180	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
B2J77_17185	ENOG4105C3J	Cysteine desulfurase
B2J77_17190	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
B2J77_17195	ENOG4105D7W	serine acetyltransferase
B2J77_17205	ENOG4105ECY	inositol monophosphatase
B2J77_17210	ENOG4107MBR	17 kDa surface antigen
B2J77_17215	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
B2J77_17220	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
B2J77_17225	ENOG4105VIE	preprotein translocase, subunit YajC
B2J77_17230	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
B2J77_17235	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
B2J77_17250	ENOG4105BZU	Histidine kinase
B2J77_17255	ENOG4105FFC	UPF0187 protein
B2J77_17270	ENOG4108VA1	ABC transporter
B2J77_17275	ENOG4107T9Q	phosphonate abc transporter
B2J77_17280	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
B2J77_17285	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
B2J77_17305	ENOG4105PI0	Ferredoxin
B2J77_17315	ENOG4105CHM	Aminotransferase
B2J77_17320	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
B2J77_17325	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
B2J77_17330	ENOG4105CCU	oxidase (Subunit III)
B2J77_17335	ENOG4105BZ9	Cytochrome C oxidase, subunit I
B2J77_17340	ENOG4105E2S	oxidase) subunit II
B2J77_17345	ENOG4105RXK	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
B2J77_17350	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
B2J77_17370	ENOG4108JJA	ABC, transporter
B2J77_17375	ENOG4107QZV	Type I secretion membrane fusion protein
B2J77_17400	ENOG4105J5J	Outer membrane porin
B2J77_17415	ENOG4105VRT	cytoplasmic protein
B2J77_17420	ENOG4105DM4	PTS System
B2J77_17425	ENOG4105DE4	1-phosphofructokinase
B2J77_17430	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
B2J77_17435	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
B2J77_17440	ENOG4105EYA	deoxyribonuclease
B2J77_17445	ENOG4106A72	regulatory protein AmpE
B2J77_17450	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
B2J77_17460	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
B2J77_17465	ENOG4105C3M	thioredoxin reductase
B2J77_17470	ENOG4105EXN	Sulfate transport protein CysZ
B2J77_17480	ENOG4107SDU	Methyl-accepting chemotaxis
B2J77_17490	ENOG4108V06	Glutathione peroxidase
B2J77_17495	ENOG4108YZY	peptidylprolyl cis-trans isomerase
B2J77_17505	ENOG4105C6K	Malic enzyme
B2J77_17510	ENOG4108ZG0	Ompa motb domain protein
B2J77_17525	ENOG41061ZR	Transcriptional regulator
B2J77_17530	ENOG4105D25	secreted protein
B2J77_17540	ENOG4105CEY	Amp-dependent synthetase and ligase
B2J77_17545	ENOG4105C5I	Dehydrogenase
B2J77_17550	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
B2J77_17560	ENOG4105D0M	Protease HtpX homolog
B2J77_17565	ENOG4108RAV	Conserved protein
B2J77_17605	ENOG4105DWT	malate dehydrogenase (quinone)
B2J77_17620	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
B2J77_17625	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
B2J77_17630	ENOG4105C2W	permease
B2J77_17635	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
B2J77_17640	ENOG4105ECP	epimerase
B2J77_17645	ENOG4108QDE	fad dependent oxidoreductase
B2J77_17655	ENOG4108XDN	Transcriptional regulator
B2J77_17660	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
B2J77_17670	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
B2J77_17675	ENOG4105D06	uba thif-type nad fad binding protein
B2J77_17680	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
B2J77_17685	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
B2J77_17690	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
B2J77_17705	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
B2J77_17710	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
B2J77_17715	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
B2J77_17725	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
B2J77_17730	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
B2J77_17735	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
B2J77_17740	ENOG4105C3G	gtp-binding protein
B2J77_17755	ENOG4105EGS	Mechanosensitive ion channel
B2J77_17760	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
B2J77_17770	ENOG4108SF5	RNA Polymerase
B2J77_17785	ENOG4105EU0	Major facilitator Superfamily
B2J77_17800	ENOG410801F	ribosomal-protein-alanine acetyltransferase
B2J77_17825	ENOG4108RH0	Crea protein
B2J77_17830	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
B2J77_17835	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B2J77_17840	ENOG4105K46	50S ribosomal protein l27
B2J77_17845	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
B2J77_17850	ENOG4105EAH	synthase
B2J77_17855	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
B2J77_17865	ENOG4108V1T	peptidylprolyl cis-trans isomerase
B2J77_17870	ENOG4108TEB	UPF0114 protein
B2J77_17880	ENOG4105DAN	ATP-dependent protease
B2J77_17905	ENOG4105D82	Glutamate dehydrogenase
B2J77_17910	ENOG4105C5H	ABC transporter
B2J77_17920	ENOG4105BZU	Histidine kinase
B2J77_17925	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
B2J77_17930	ENOG41068CG	regulatoR
B2J77_17935	ENOG4105BZU	Histidine kinase
B2J77_17940	ENOG4105BZU	Histidine kinase
B2J77_17945	ENOG4105BZU	Histidine kinase
B2J77_17950	ENOG4105GQR	Chaperone
B2J77_17960	ENOG4105CW0	outer membrane usher protein
B2J77_17965	ENOG4105GQR	Chaperone
B2J77_17980	ENOG4105C94	Transporter
B2J77_17990	ENOG4105EAB	amino acid AbC transporter
B2J77_17995	ENOG4105E5Q	amino acid AbC transporter
B2J77_18000	ENOG4107SDU	Methyl-accepting chemotaxis
B2J77_18005	ENOG4105BZU	Histidine kinase
B2J77_18010	ENOG4105CQZ	Histidine kinase
B2J77_18050	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
B2J77_18115	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
B2J77_18120	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
B2J77_18135	ENOG4105CEP	NADH dehydrogenase
B2J77_18140	ENOG4107VFR	oxidoreductase
B2J77_18160	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
B2J77_18165	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
B2J77_18170	ENOG4105C34	Pseudouridine synthase
B2J77_18175	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B2J77_18185	ENOG4108DN8	FAD dependent oxidoreductase
B2J77_18215	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
B2J77_18220	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
B2J77_18225	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
B2J77_18230	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
B2J77_18235	ENOG4105DTN	riboflavin biosynthesis protein ribF
B2J77_18240	ENOG4105CJR	Integral membrane protein (MviN
B2J77_18245	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
B2J77_18250	ENOG4105DY2	Paraquat-inducible protein b
B2J77_18255	ENOG4105F1S	paraquat-inducible protein a
B2J77_18260	ENOG4105F1S	paraquat-inducible protein a
B2J77_18290	ENOG4105C26	Dehydrogenase
B2J77_18300	ENOG4105EVZ	LysR family transcriptional regulator
B2J77_18305	ENOG4108R86	Transcriptional regulator
B2J77_18315	ENOG4105CHR	reductase
B2J77_18320	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
B2J77_18330	ENOG4105C2C	drug resistance transporter, Bcr CflA
B2J77_18335	ENOG4105C59	p-type ATPase
B2J77_18345	ENOG4105C59	p-type ATPase
B2J77_18350	ENOG4108Z6Z	Transcriptional regulator
B2J77_18355	ENOG4105C8Q	Methyl-accepting chemotaxis
B2J77_18360	ENOG4105R1U	AraC Family Transcriptional Regulator
B2J77_18365	ENOG4105CHU	acetyl-coa acetyltransferase
B2J77_18380	ENOG4105CHR	reductase
B2J77_18395	ENOG4106371	Methyltransferase
B2J77_18415	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
B2J77_18420	ENOG4108JQB	penicillin-binding protein 1C
B2J77_18430	ENOG4105DN3	alpha-2-macroglobulin domain protein
B2J77_18435	ENOG4107R73	Mate efflux family protein
B2J77_18440	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
B2J77_18445	ENOG4108ZJT	translation initiation factor, Sui1
B2J77_18450	ENOG4105PTV	Nudix Hydrolase
B2J77_18460	ENOG4105BZU	Histidine kinase
B2J77_18465	ENOG4108W2P	Methyl-accepting chemotaxis
B2J77_18470	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
B2J77_18475	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
B2J77_18480	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
B2J77_18485	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
B2J77_18490	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
B2J77_18495	ENOG4106Z86	ATP-nad acox kinase
B2J77_18500	ENOG4107R0V	Pyruvate dehydrogenase
B2J77_18505	ENOG4105CPP	Dehydrogenase, E1 component
B2J77_18510	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
B2J77_18525	ENOG4105K4T	epimerase
B2J77_18535	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
B2J77_18540	ENOG4105DFU	Cell wall formation (By similarity)
B2J77_18545	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
B2J77_18550	ENOG4105C26	Dehydrogenase
B2J77_18555	ENOG4105CUB	amino acid
B2J77_18560	ENOG4105CPD	ethanolamine ammonia-lyase
B2J77_18565	ENOG4107FQ9	ethanolamine ammonia-lyase
B2J77_18570	ENOG4105DQR	SNARE associated Golgi
B2J77_18575	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
B2J77_18580	ENOG4105F0N	pyrophosphate phospho-hydrolase
B2J77_18590	ENOG4105CNM	Receptor
B2J77_18600	ENOG410804D	Sensor Signal Transduction Histidine Kinase
B2J77_18610	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
B2J77_18615	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
B2J77_18620	ENOG4105CTB	Polyprenyl synthetase
B2J77_18625	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
B2J77_18635	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
B2J77_18645	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
B2J77_18655	ENOG4108ZAI	phosphatidylglycerophosphatase a
B2J77_18660	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
B2J77_18665	ENOG4107YIM	Involved in the transcription termination process (By similarity)
B2J77_18670	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
B2J77_18675	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
B2J77_18685	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
B2J77_18690	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
B2J77_18700	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
B2J77_18705	ENOG4107QR8	Thioredoxin
B2J77_18720	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
B2J77_18735	ENOG4105EIF	outer membrane protein W
B2J77_18740	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
B2J77_18760	ENOG4105HDK	L-asparaginase
B2J77_18770	ENOG4105EM7	Selenocysteine-specific translation elongation factor
B2J77_18775	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
B2J77_18780	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
B2J77_18785	ENOG4108MG3	formate dehydrogenase
B2J77_18790	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
B2J77_18795	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
B2J77_18800	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
B2J77_18805	ENOG4108UUM	single-stranded DNA-binding protein
B2J77_18810	ENOG4107RDB	Major Facilitator
B2J77_18815	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
B2J77_18820	ENOG4108UWD	Iron-storage protein
B2J77_18825	ENOG4105CH6	catalase
B2J77_18830	ENOG4108ZT0	50S ribosomal protein l17
B2J77_18835	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B2J77_18840	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
B2J77_18845	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
B2J77_18850	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B2J77_18860	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
B2J77_18865	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
B2J77_18870	ENOG4105VPB	50S ribosomal protein L30
B2J77_18875	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
B2J77_18880	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
B2J77_18885	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
B2J77_18890	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
B2J77_18895	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
B2J77_18900	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B2J77_18905	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
B2J77_18910	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
B2J77_18915	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
B2J77_18920	ENOG41083MP	50s ribosomal protein l29
B2J77_18925	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
B2J77_18930	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
B2J77_18940	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
B2J77_18945	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B2J77_18950	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
B2J77_18955	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
B2J77_18960	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
B2J77_18965	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
B2J77_18970	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
B2J77_18975	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
B2J77_18980	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
B2J77_18985	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
B2J77_18990	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B2J77_18995	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B2J77_19000	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
B2J77_19005	ENOG4108VZM	50s ribosomal protein L10
B2J77_19010	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
B2J77_19015	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
B2J77_19020	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
B2J77_19025	ENOG4105PM1	preprotein translocase subunit SecE
B2J77_19035	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
B2J77_19060	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
B2J77_19065	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
B2J77_19095	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
B2J77_19100	ENOG4105DR5	peptidase
B2J77_19105	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
B2J77_19110	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
B2J77_19115	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
B2J77_19120	ENOG4108YXA	Membrane
B2J77_19125	ENOG4108W6C	Dehydrogenase
B2J77_19130	ENOG4107YU2	histidine triad (hIT) protein
B2J77_19135	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
B2J77_19145	ENOG4108UKZ	OsmC family
B2J77_19150	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
B2J77_19160	ENOG4105DK0	Indole-3-glycerol phosphate synthase
B2J77_19165	ENOG4108I0Q	anthranilate phosphoribosyltransferase
B2J77_19170	ENOG4105DDQ	anthranilate synthase
B2J77_19175	ENOG4107SUD	Esterase
B2J77_19180	ENOG4105CRQ	synthase (Component I)
B2J77_19185	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
B2J77_19190	ENOG4105DJV	ribulose-phosphate 3-epimerase
B2J77_19200	ENOG4105F38	ABC transporter, permease
B2J77_19210	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B2J77_19215	ENOG4105WH1	Two component transcriptional regulator luxr family
B2J77_19230	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
B2J77_19235	ENOG4108S0S	Nucleotidyl transferase
B2J77_19240	ENOG4105EHM	Aminoglycoside phosphotransferase
B2J77_19245	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
B2J77_19250	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
B2J77_19255	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
B2J77_19260	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
B2J77_19265	ENOG4105NWN	ApaG protein
B2J77_19270	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
B2J77_19275	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
B2J77_19280	ENOG4105CYN	Serine protein kinase
B2J77_19285	ENOG4106AKX	UPF0229 protein
B2J77_19290	ENOG4105ED1	spovr family
B2J77_19295	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
B2J77_19305	ENOG4107ZVW	dihydroneopterin aldolase
B2J77_19310	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
B2J77_19315	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
B2J77_19320	ENOG4105VCC	30S ribosomal protein S21
B2J77_19325	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
B2J77_19395	ENOG4105CEC	DNA methylase N-4 N-6
B2J77_19405	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
B2J77_19430	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
B2J77_19440	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
B2J77_19445	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
B2J77_19450	ENOG4106URE	pyrroloquinoline quinone biosynthesis protein d
B2J77_19455	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
B2J77_19470	ENOG4105C8Y	Acetylornithine aminotransferase
B2J77_19475	ENOG4105DND	Transcriptional regulator
B2J77_19480	ENOG4105CSU	acyl-Coa dehydrogenase
B2J77_19485	ENOG4106TD9	Diguanylate cyclase
B2J77_19490	ENOG4105CSU	acyl-Coa dehydrogenase
B2J77_19510	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
B2J77_19515	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
B2J77_19520	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
B2J77_19530	ENOG4105F4R	Transcriptional regulator mode
B2J77_19535	ENOG4105E27	serine threonine protein kinase
B2J77_19540	ENOG4105FR1	rard protein
B2J77_19550	ENOG4107QP3	malate synthase g
B2J77_19565	ENOG41083X2	DNA polymerase III, epsilon subunit
B2J77_19590	ENOG4107543	(lipo)polysaccharide
B2J77_19595	ENOG4107RJ7	Glycosyl transferase (Group 1
B2J77_19600	ENOG4105D16	lipopolysaccharide heptosyltransferase i
B2J77_19605	ENOG4105XA0	heptosyltransferase ii
B2J77_19610	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
B2J77_19620	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
B2J77_19625	ENOG4107QSN	dihydrolipoamide acetyltransferase
B2J77_19630	ENOG4105BZU	Histidine kinase
B2J77_19635	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
B2J77_19650	ENOG4106HNH	Acyl-transferase
B2J77_19655	ENOG4105CUB	amino acid
B2J77_19730	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
B2J77_19755	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
B2J77_19765	ENOG4105DVW	rieske (2Fe-2S)
B2J77_19780	ENOG4105C10	Electron transfer flavoprotein
B2J77_19785	ENOG4105DF6	Fe-S oxidoreductase
B2J77_19820	ENOG4105ECQ	AraC Family Transcriptional Regulator
B2J77_19830	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
B2J77_19835	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
B2J77_19850	ENOG4105ECQ	AraC Family Transcriptional Regulator
B2J77_19855	ENOG4105EJQ	L-serine dehydratase
B2J77_19865	ENOG4108HQS	Glycine betaine
B2J77_19870	ENOG4108IJ7	Glycine betaine
B2J77_19875	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
B2J77_19880	ENOG4105EGS	Mechanosensitive ion channel
B2J77_19885	ENOG4105CNG	UPF0061 protein
B2J77_19890	ENOG4105K63	Thioredoxin
B2J77_19905	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
B2J77_19925	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
B2J77_19940	ENOG4106NZI	LysR family Transcriptional regulator
B2J77_19945	ENOG4105D94	Major Facilitator Superfamily
B2J77_19955	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
B2J77_19960	ENOG4105BZ8	glutamate synthase
B2J77_19965	ENOG4105CBC	glutamate synthase
B2J77_19975	ENOG4105D49	3-dehydroquinate synthase
B2J77_19980	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
B2J77_19985	ENOG4105E4G	Type IV pilus
B2J77_20005	ENOG4108JQC	penicillin-binding protein 1A
B2J77_20010	ENOG4105C6K	Malic enzyme
B2J77_20020	ENOG4105VFB	Binds the 23S rRNA (By similarity)
B2J77_20025	ENOG4105C25	Primosomal protein n'
B2J77_20030	ENOG4105C75	arginyL-tRNA synthetase
B2J77_20045	ENOG4108YS0	lipoprotein YafL
B2J77_20050	ENOG4105CZX	twitching motility protein
B2J77_20055	ENOG4105DFA	alanine racemase domain protein
B2J77_20060	ENOG4105II7	pyrroline-5-carboxylate reductase
B2J77_20065	ENOG4108VIA	integral membrane protein
B2J77_20070	ENOG4105DWV	Homoserine O-trans-acetylase
B2J77_20075	ENOG4105DWV	Homoserine O-trans-acetylase
B2J77_20085	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
B2J77_20090	ENOG4105CSA	Coproporphyrinogen iii oxidase
B2J77_20100	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
B2J77_20105	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
B2J77_20110	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
B2J77_20120	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
B2J77_20125	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B2J77_20130	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
B2J77_20135	ENOG4105CAK	Cell division ATP-binding protein ftsE
B2J77_20140	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
B2J77_20160	ENOG4106H78	methyltransferase
B2J77_20175	ENOG4105DNZ	Alpha Beta Hydrolase
B2J77_20180	ENOG4105KHC	sulfurtransferase
B2J77_20190	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
B2J77_20195	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
B2J77_20200	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
B2J77_20205	ENOG4108HU6	Metal dependent phosphohydrolase
B2J77_20210	ENOG4107R7Y	intracellular protease Pfpi family
B2J77_20215	ENOG4105DR4	Methyltransferase
B2J77_20220	ENOG4105CJW	magnesium transporter
B2J77_20225	ENOG4105C01	Dihydroxy-acid dehydratase
B2J77_20245	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
B2J77_20255	ENOG4105W1Y	Transcriptional regulator
B2J77_20385	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
B2J77_20405	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
B2J77_20410	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
B2J77_20415	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
B2J77_20420	ENOG4105HF0	Membrane
B2J77_20430	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
B2J77_20435	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
B2J77_20445	ENOG4105C7B	Threonine dehydratase
B2J77_20450	ENOG4105E66	phosphoriboisomerase A
B2J77_20455	ENOG4108ZK4	sdia-regulated domain-containing protein
B2J77_20465	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
B2J77_20470	ENOG4105CQB	FAD linked oxidase domain protein
B2J77_20475	ENOG4108JQ1	Dehydrogenase
B2J77_20510	ENOG4105D01	(LipO)protein
B2J77_20515	ENOG4107SM7	Transcriptional regulator
B2J77_20525	ENOG4108IJ6	ABC transporter
B2J77_20530	ENOG4105ECW	sulfate abc transporter
B2J77_20535	ENOG4108I5D	sulfate abc transporter
B2J77_20540	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
B2J77_20550	ENOG4105BZS	acriflavin resistance protein
B2J77_20555	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
B2J77_20560	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
B2J77_20565	ENOG4105D38	putrescine abc transporter
B2J77_20570	ENOG4105F38	ABC transporter, permease
B2J77_20575	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B2J77_20580	ENOG4108HM4	ABC transporter
B2J77_20590	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
B2J77_20595	ENOG4105CFQ	glutamine synthetase
B2J77_20605	ENOG4105CFQ	glutamine synthetase
B2J77_20610	ENOG4108DQ3	n-acetylglutamate synthase
B2J77_20625	ENOG4108XM1	transcriptional regulator AsnC family
B2J77_20635	ENOG4107QHF	type ii secretion system protein e
B2J77_20645	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
B2J77_20650	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
B2J77_20655	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
B2J77_20660	ENOG4107QKW	extracellular solute-binding protein family 1
B2J77_20665	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
B2J77_20675	ENOG4105D0A	hydroxylase
B2J77_20680	ENOG4107RAQ	aminopeptidase
B2J77_20685	ENOG4105E07	UPF0149 protein
B2J77_20695	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
B2J77_20705	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
B2J77_20740	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
B2J77_20750	ENOG4105K63	Thioredoxin
B2J77_20755	ENOG4105C9X	ppx gppa phosphatase
B2J77_20760	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
B2J77_20765	ENOG4105KHU	inner membrane protein YohD
B2J77_20770	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
B2J77_20775	ENOG4108UPT	UPF0178 protein
B2J77_20780	ENOG4107T0K	Adenylate cyclase
B2J77_20785	ENOG4105NXH	GreA GreB family elongation factor
B2J77_20795	ENOG4105XQ6	frataxin-like protein
B2J77_20810	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
B2J77_20815	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
B2J77_20825	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
B2J77_20830	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
B2J77_20840	ENOG4105BZU	Histidine kinase
B2J77_20845	ENOG4108YZA	Nitrogen regulatory protein pii
B2J77_20850	ENOG4105W0Z	cytoplasmic protein
B2J77_20860	ENOG4105C0P	Mg chelatase subunit ChlI
B2J77_20865	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
B2J77_20875	ENOG4105CC0	LysR family Transcriptional regulator
B2J77_20895	ENOG4105CHJ	isochorismatase hydrolase
B2J77_20905	ENOG4105CJP	fad dependent oxidoreductase
B2J77_20910	ENOG4105C26	Dehydrogenase
B2J77_20915	ENOG4105ETT	transcriptional Regulator, LysR family
B2J77_20920	ENOG4105E32	cytoplasmic protein
B2J77_20935	ENOG4107QI1	Mate efflux family protein
B2J77_20940	ENOG4105BZU	Histidine kinase
B2J77_20945	ENOG4105C4R	Atp-dependent dna helicase
B2J77_20950	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
B2J77_20955	ENOG4105CYC	Transferase
B2J77_20965	ENOG4105MPD	Cytochrome
B2J77_20975	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
B2J77_20980	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
B2J77_20985	ENOG4105EW9	transcriptional regulator AsnC family
B2J77_20995	ENOG4105CJP	fad dependent oxidoreductase
B2J77_21005	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B2J77_21010	ENOG4107RZC	phospholipase d
B2J77_21020	ENOG4105C26	Dehydrogenase
B2J77_21030	ENOG4105W0E	50S ribosomal protein L33
B2J77_21035	ENOG4105KDC	50s ribosomal protein l28
B2J77_21040	ENOG4105DEF	Extracellular solute-binding protein, family 5
B2J77_21045	ENOG4105W5Q	DNA repair protein (RadC
B2J77_21050	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
B2J77_21055	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
B2J77_21060	ENOG4107QKV	phosphomannomutase
B2J77_21065	ENOG4105CAS	nag kinase
B2J77_21070	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
B2J77_21075	ENOG4105CGK	Exodeoxyribonuclease III
B2J77_21085	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
B2J77_21090	ENOG4105DSJ	YicC domain protein
B2J77_21095	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
B2J77_21105	ENOG4105CFQ	glutamine synthetase
B2J77_21115	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
B2J77_21120	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
B2J77_21125	ENOG4105KME	endoribonuclease L-psp
B2J77_21145	ENOG4108ZZF	transport protein (ExbD)
B2J77_21150	ENOG4105YHG	TonB family
B2J77_21155	ENOG4105C5Q	Transcriptional regulator
B2J77_21160	ENOG4105CB5	ATP-dependent DNA helicase recG
B2J77_21175	ENOG4105NYX	DNA-binding protein
B2J77_21180	ENOG4107QZF	nitrite reductase NADPH large subunit
B2J77_21190	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
B2J77_21195	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
B2J77_21200	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
B2J77_21205	ENOG4105BZU	Histidine kinase
B2J77_21210	ENOG4105C37	(CBS) domain
B2J77_21215	ENOG4105DR5	peptidase
B2J77_21220	ENOG4108VYJ	response regulator receiver protein
B2J77_21225	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
B2J77_21230	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
B2J77_21235	ENOG4105C8U	phosphate abc transporter
B2J77_21240	ENOG4105C8U	phosphate abc transporter
B2J77_21250	ENOG4105CSH	Transporter
B2J77_21255	ENOG4105NAU	thioesterase Superfamily protein
B2J77_21275	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
B2J77_21280	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
B2J77_21290	ENOG4107YNJ	LysR family Transcriptional regulator
B2J77_21295	ENOG4108IJ0	Aspartate ammonia-lyase
B2J77_21300	ENOG4108ZX5	transcriptional regulator
B2J77_21305	ENOG41067B5	Histone deacetylase superfamily protein
B2J77_21335	ENOG4107QSA	Oxaloacetate decarboxylase
B2J77_21340	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
B2J77_21345	ENOG4105DUM	transcriptional regulator, lysR family
B2J77_21355	ENOG4106KNT	transcriptional regulator
B2J77_21360	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
B2J77_21370	ENOG4105C4R	Atp-dependent dna helicase
B2J77_21385	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
B2J77_21395	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
B2J77_21405	ENOG4105CKI	cobalamin synthesis protein
B2J77_21420	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
B2J77_21425	ENOG41060X7	Protein of unknown function (DUF3617)
B2J77_21430	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
B2J77_21435	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
B2J77_21445	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
B2J77_21450	ENOG410804X	Transcriptional regulator
