locus-tag	class	description
GEV41_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GEV41_00010	COG0592	DNA-directed DNA polymerase activity
GEV41_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GEV41_00020	COG0187	DNA topoisomerase II activity
GEV41_00110	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GEV41_00185	COG3328	transposase activity
GEV41_00205	COG2194	sulfuric ester hydrolase activity
GEV41_00230	COG3039	Transposase
GEV41_00265	COG0463	Glycosyl transferase, family 2
GEV41_00385	COG0477	Major facilitator Superfamily
GEV41_00395	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GEV41_00400	COG0751	glycine-tRNA ligase activity
GEV41_00405	COG0752	glycyl-tRNA synthetase alpha subunit
GEV41_00410	COG2818	Glycosylase
GEV41_00425	COG0569	domain protein
GEV41_00430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GEV41_00435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GEV41_00440	COG0242	peptide deformylase activity
GEV41_00445	COG0758	DNA mediated transformation
GEV41_00450	COG0009	L-threonylcarbamoyladenylate synthase
GEV41_00460	COG3328	transposase activity
GEV41_00475	COG0408	coproporphyrinogen oxidase activity
GEV41_00480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GEV41_00485	COG0659	secondary active sulfate transmembrane transporter activity
GEV41_00495	COG3119	arylsulfatase activity
GEV41_00515	COG0159	tryptophan synthase activity
GEV41_00520	COG0133	tryptophan synthase activity
GEV41_00535	COG3360	Dodecin
GEV41_00545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV41_00550	COG1764	response to oxidative stress
GEV41_00580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GEV41_00585	COG0339	signal peptide processing
GEV41_00590	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GEV41_00610	COG0659	secondary active sulfate transmembrane transporter activity
GEV41_00625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GEV41_00630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GEV41_00635	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GEV41_00660	COG1612	heme a metabolic process
GEV41_00665	COG0109	protoheme IX farnesyltransferase activity
GEV41_00680	COG2011	ABC-type metal ion transport system permease component
GEV41_00685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GEV41_00700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GEV41_00705	COG1121	(ABC) transporter
GEV41_00710	COG0735	belongs to the Fur family
GEV41_00715	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GEV41_00735	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GEV41_00740	COG3245	cytochrome
GEV41_00750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GEV41_00765	COG3023	N-Acetylmuramoyl-L-alanine amidase
GEV41_00770	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GEV41_00775	COG5002	protein histidine kinase activity
GEV41_00780	COG2204	response regulator
GEV41_00805	COG1301	dicarboxylic acid transport
GEV41_00810	COG0700	Nucleoside recognition
GEV41_00825	COG1127	ABC transporter
GEV41_00830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GEV41_00845	COG1283	sodium-dependent phosphate transmembrane transporter activity
GEV41_00850	COG0861	Integral membrane protein TerC family
GEV41_00855	COG2851	Citrate transporter
GEV41_00890	COG0427	acetyl-CoA hydrolase
GEV41_00910	COG0583	DNA-binding transcription factor activity
GEV41_00915	COG1960	acyl-CoA dehydrogenase activity
GEV41_00985	COG1802	Transcriptional regulator
GEV41_00995	COG5001	Diguanylate cyclase
GEV41_00995	COG3300	MHYT domain
GEV41_01000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GEV41_01025	COG2175	clavaminate synthase activity
GEV41_01040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GEV41_01060	COG1289	transmembrane transporter activity
GEV41_01070	COG1566	PFAM secretion protein HlyD family protein
GEV41_01080	COG0672	)-iron permease
GEV41_01095	COG0625	glutathione transferase activity
GEV41_01100	COG0165	Argininosuccinate lyase
GEV41_01110	COG0181	hydroxymethylbilane synthase activity
GEV41_01130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GEV41_01155	COG0488	(ABC) transporter
GEV41_01165	COG1280	lysine exporter protein (LysE YggA)
GEV41_01195	COG0517	IMP dehydrogenase activity
GEV41_01195	COG0516	GMP reductase activity
GEV41_01215	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_01220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GEV41_01245	COG2011	ABC-type metal ion transport system permease component
GEV41_01250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GEV41_01255	COG1464	Belongs to the NlpA lipoprotein family
GEV41_01290	COG1045	serine acetyltransferase
GEV41_01300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GEV41_01305	COG2175	clavaminate synthase activity
GEV41_01310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GEV41_01315	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GEV41_01320	COG4521	taurine ABC transporter
GEV41_01330	COG0450	alkyl hydroperoxide reductase
GEV41_01335	COG0431	NADPH-dependent FMN reductase
GEV41_01340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GEV41_01345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV41_01350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GEV41_01355	COG1116	anion transmembrane transporter activity
GEV41_01370	COG2918	glutathione biosynthetic process
GEV41_01380	COG2183	response to ionizing radiation
GEV41_01385	COG0745	RESPONSE REGULATOR receiver
GEV41_01395	COG0189	ligase activity
GEV41_01400	COG0189	ligase activity
GEV41_01400	COG4067	protein conserved in archaea
GEV41_01405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GEV41_01415	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GEV41_01425	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GEV41_01445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GEV41_01450	COG1652	LysM domain
GEV41_01455	COG1011	Hydrolase
GEV41_01460	COG0494	nUDIX hydrolase
GEV41_01490	COG2957	Belongs to the agmatine deiminase family
GEV41_01510	COG0069	glutamate synthase activity
GEV41_01520	COG0745	RESPONSE REGULATOR receiver
GEV41_01535	COG2199	diguanylate cyclase activity
GEV41_01535	COG2203	Gaf domain
GEV41_01565	COG0582	viral genome integration into host DNA
GEV41_01595	COG4215	(ABC) transporter
GEV41_01635	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GEV41_01650	COG2223	nitrite transmembrane transporter activity
GEV41_01655	COG0131	Imidazoleglycerol-phosphate dehydratase
GEV41_01660	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GEV41_01670	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GEV41_01675	COG0107	imidazoleglycerol-phosphate synthase activity
GEV41_01680	COG4175	Glycine betaine
GEV41_01685	COG4176	ABC-type proline glycine betaine transport system permease component
GEV41_01695	COG1760	l-serine dehydratase
GEV41_01710	COG3291	Pkd domain containing protein
GEV41_01720	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV41_01725	COG3246	L-lysine catabolic process to acetate
GEV41_01765	COG0446	pyridine nucleotide-disulphide oxidoreductase
GEV41_01765	COG1902	pentaerythritol trinitrate reductase activity
GEV41_01770	COG0247	lactate metabolic process
GEV41_01770	COG2181	nitrate reductase activity
GEV41_01775	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GEV41_01790	COG4638	Rieske (2fe-2S)
GEV41_01800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GEV41_01800	COG1017	nitric oxide dioxygenase activity
GEV41_01825	COG0840	transmembrane signaling receptor activity
GEV41_01835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GEV41_01865	COG1063	alcohol dehydrogenase
GEV41_01880	COG0204	Acyl-transferase
GEV41_01890	COG0745	RESPONSE REGULATOR receiver
GEV41_01895	COG2205	protein histidine kinase activity
GEV41_01900	COG4452	Inner membrane protein CreD
GEV41_01910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GEV41_01930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GEV41_01945	COG0438	transferase activity, transferring glycosyl groups
GEV41_01985	COG4774	siderophore transport
GEV41_01990	COG3712	iron ion homeostasis
GEV41_01995	COG1595	DNA-templated transcription, initiation
GEV41_02000	COG2176	DNA-directed DNA polymerase activity
GEV41_02005	COG0516	GMP reductase activity
GEV41_02005	COG0517	IMP dehydrogenase activity
GEV41_02015	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GEV41_02030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GEV41_02035	COG3585	molybdate ion transport
GEV41_02035	COG2005	Transcriptional regulator
GEV41_02040	COG1040	competence protein
GEV41_02045	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GEV41_02050	COG0156	8-amino-7-oxononanoate synthase activity
GEV41_02075	COG1960	acyl-CoA dehydrogenase activity
GEV41_02085	COG3706	GGDEF domain
GEV41_02090	COG1960	acyl-CoA dehydrogenase activity
GEV41_02095	COG0583	DNA-binding transcription factor activity
GEV41_02100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GEV41_02115	COG0535	radical SAM domain protein
GEV41_02125	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
GEV41_02135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GEV41_02145	COG1025	Belongs to the peptidase M16 family
GEV41_02150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GEV41_02170	COG1396	sequence-specific DNA binding
GEV41_02170	COG3800	Transcriptional regulator
GEV41_02185	COG4993	Dehydrogenase
GEV41_02210	COG3436	PFAM IS66 Orf2 family protein
GEV41_02215	COG3846	protein secretion by the type IV secretion system
GEV41_02265	COG0358	DNA primase activity
GEV41_02270	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GEV41_02275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GEV41_02280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GEV41_02285	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GEV41_02295	COG0617	tRNA 3'-terminal CCA addition
GEV41_02300	COG2719	SpoVR family
GEV41_02305	COG2718	Belongs to the UPF0229 family
GEV41_02310	COG2766	serine protein kinase
GEV41_02315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GEV41_02320	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GEV41_02325	COG2967	ApaG domain
GEV41_02330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GEV41_02335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GEV41_02340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GEV41_02345	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GEV41_02350	COG3178	'Phosphotransferase
GEV41_02355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GEV41_02370	COG4585	Histidine kinase
GEV41_02375	COG2197	response regulator
GEV41_02380	COG3842	ATPase activity
GEV41_02390	COG1176	ABC-type spermidine putrescine transport system, permease component I
GEV41_02400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GEV41_02405	COG0546	phosphoglycolate phosphatase activity
GEV41_02410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GEV41_02420	COG3240	lipase activity
GEV41_02420	COG4625	pathogenesis
GEV41_02425	COG0512	Glutamine amidotransferase of anthranilate synthase
GEV41_02430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GEV41_02435	COG0134	indole-3-glycerol-phosphate synthase activity
GEV41_02450	COG1765	OsmC-like protein
GEV41_02460	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GEV41_02465	COG0537	adenosine 5'-monophosphoramidase activity
GEV41_02470	COG0300	oxidoreductase activity
GEV41_02485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GEV41_02490	COG0316	Belongs to the HesB IscA family
GEV41_02495	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GEV41_02500	COG0739	heme binding
GEV41_02510	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GEV41_02540	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GEV41_02540	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GEV41_02545	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GEV41_02570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GEV41_02590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GEV41_02595	COG0081	regulation of translation
GEV41_02600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GEV41_02605	COG0222	ribosome binding
GEV41_02610	COG0085	RNA polymerase activity
GEV41_02615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GEV41_02620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GEV41_02625	COG0049	tRNA binding
GEV41_02630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GEV41_02635	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GEV41_02640	COG0051	transcription antitermination factor activity, RNA binding
GEV41_02645	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GEV41_02650	COG0088	Forms part of the polypeptide exit tunnel
GEV41_02655	COG0089	rRNA binding
GEV41_02660	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GEV41_02665	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GEV41_02670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GEV41_02675	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GEV41_02680	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GEV41_02685	COG0255	Belongs to the universal ribosomal protein uL29 family
GEV41_02690	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GEV41_02695	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GEV41_02700	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GEV41_02705	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GEV41_02710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GEV41_02715	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GEV41_02720	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GEV41_02725	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GEV41_02730	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GEV41_02735	COG1841	ribosomal large subunit assembly
GEV41_02740	COG0200	Binds to the 23S rRNA
GEV41_02750	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GEV41_02755	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GEV41_02760	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GEV41_02765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GEV41_02770	COG0202	RNA polymerase activity
GEV41_02775	COG0203	ribosomal protein L17
GEV41_02780	COG0753	catalase activity
GEV41_02785	COG2193	ferroxidase activity
GEV41_02790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GEV41_02795	COG2814	Major facilitator Superfamily
GEV41_02800	COG0629	single-stranded DNA binding
GEV41_02805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GEV41_02815	COG4221	oxidoreductase activity
GEV41_02825	COG0437	4 iron, 4 sulfur cluster binding
GEV41_02830	COG2864	formate dehydrogenase
GEV41_02835	COG3058	Necessary for formate dehydrogenase activity
GEV41_02840	COG1921	L-seryl-tRNASec selenium transferase activity
GEV41_02845	COG3276	selenocysteine insertion sequence binding
GEV41_02855	COG0252	asparaginase activity
GEV41_02860	COG1115	amino acid carrier protein
GEV41_02895	COG2814	Major facilitator Superfamily
GEV41_02900	COG3047	cAMP biosynthetic process
GEV41_02930	COG3118	belongs to the thioredoxin family
GEV41_02935	COG2264	protein methyltransferase activity
GEV41_02945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GEV41_02950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GEV41_02950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GEV41_02965	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GEV41_02970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GEV41_02975	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GEV41_02980	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GEV41_02990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GEV41_03000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GEV41_03005	COG4206	TonB-dependent receptor
GEV41_03020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GEV41_03025	COG0142	geranyltranstransferase activity
GEV41_03030	COG1722	exodeoxyribonuclease VII activity
GEV41_03035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GEV41_03045	COG2819	hydrolase of the alpha beta superfamily
GEV41_03085	COG2132	Multicopper oxidase
GEV41_03095	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GEV41_03100	COG3228	Belongs to the MtfA family
GEV41_03105	COG0586	Pfam SNARE associated Golgi protein
GEV41_03110	COG0456	acetyltransferase
GEV41_03115	COG4302	ethanolamine ammonia-lyase activity
GEV41_03120	COG4303	Ethanolamine ammonia lyase large subunit
GEV41_03125	COG0531	amino acid
GEV41_03130	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_03135	COG3284	Transcriptional regulator
GEV41_03140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GEV41_03155	COG0702	epimerase
GEV41_03165	COG1063	alcohol dehydrogenase
GEV41_03175	COG0022	dehydrogenase e1 component
GEV41_03180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GEV41_03190	COG3284	Transcriptional regulator
GEV41_03215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GEV41_03255	COG0023	Translation Initiation Factor
GEV41_03260	COG1166	arginine decarboxylase activity
GEV41_03275	COG0534	Mate efflux family protein
GEV41_03280	COG2373	Large extracellular alpha-helical protein
GEV41_03290	COG4953	penicillin-binding protein 1C
GEV41_03325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GEV41_03335	COG2030	dehydratase
GEV41_03340	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_03350	COG2207	Transcriptional regulator
GEV41_03355	COG0840	transmembrane signaling receptor activity
GEV41_03365	COG2217	Heavy metal translocating P-type atpase
GEV41_03380	COG2814	Major facilitator Superfamily
GEV41_03395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GEV41_03405	COG1739	Uncharacterized protein family UPF0029
GEV41_03410	COG1309	transcriptional regulator
GEV41_03470	COG2995	paraquat-inducible protein a
GEV41_03475	COG2995	paraquat-inducible protein a
GEV41_03480	COG3008	intermembrane lipid transfer
GEV41_03485	COG0268	Binds directly to 16S ribosomal RNA
GEV41_03495	COG0196	riboflavin kinase activity
GEV41_03500	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GEV41_03505	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GEV41_03510	COG1047	Peptidyl-prolyl cis-trans
GEV41_03515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GEV41_03545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_03570	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV41_03610	COG0542	response to heat
GEV41_03640	COG1252	NADH dehydrogenase
GEV41_03665	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GEV41_03670	COG0237	dephospho-CoA kinase activity
GEV41_03730	COG0039	L-malate dehydrogenase activity
GEV41_03745	COG0765	amino acid transport
GEV41_03750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV41_03765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GEV41_03780	COG0488	(ABC) transporter
GEV41_03785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GEV41_03790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GEV41_03810	COG1067	ATP-dependent peptidase activity
GEV41_03820	COG2862	Uncharacterized protein family, UPF0114
GEV41_03830	COG0545	Peptidyl-prolyl cis-trans isomerase
GEV41_03835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GEV41_03840	COG2824	Alkylphosphonate utilization operon protein PhnA
GEV41_03845	COG0142	geranyltranstransferase activity
GEV41_03850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GEV41_03855	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GEV41_03860	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GEV41_03865	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GEV41_03870	COG3045	CreA protein
GEV41_03895	COG0456	acetyltransferase
GEV41_03930	COG2223	nitrite transmembrane transporter activity
GEV41_03940	COG3712	iron ion homeostasis
GEV41_03945	COG1595	DNA-templated transcription, initiation
GEV41_03955	COG2169	Transcriptional regulator
GEV41_03955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GEV41_03960	COG3264	Mechanosensitive ion channel
GEV41_03960	COG1511	domain protein
GEV41_03990	COG1335	isochorismatase
GEV41_04005	COG0628	permease
GEV41_04030	COG0583	DNA-binding transcription factor activity
GEV41_04050	COG0193	aminoacyl-tRNA hydrolase activity
GEV41_04055	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GEV41_04060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GEV41_04070	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GEV41_04075	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GEV41_04115	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GEV41_04120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GEV41_04130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GEV41_04135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GEV41_04145	COG4221	oxidoreductase activity
GEV41_04150	COG0415	Belongs to the DNA photolyase family
GEV41_04155	COG0789	Transcriptional regulator
GEV41_04165	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
GEV41_04170	COG1090	epimerase
GEV41_04175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GEV41_04185	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GEV41_04215	COG0579	oxidoreductase
GEV41_04255	COG2135	peptidase activity
GEV41_04265	COG2119	membrane
GEV41_04270	COG2813	Specifically methylates the guanine in position
GEV41_04275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEV41_04285	COG0318	PFAM AMP-dependent synthetase and ligase
GEV41_04325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GEV41_04330	COG2885	chlorophyll binding
GEV41_04335	COG0857	belongs to the CobB CobQ family
GEV41_04335	COG0280	phosphate acetyltransferase
GEV41_04350	COG0386	Belongs to the glutathione peroxidase family
GEV41_04375	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GEV41_04380	COG0492	ferredoxin-NADP+ reductase activity
GEV41_04395	COG3023	N-Acetylmuramoyl-L-alanine amidase
GEV41_04405	COG0084	hydrolase, TatD family'
GEV41_04410	COG1609	Transcriptional regulator
GEV41_04420	COG1105	Belongs to the carbohydrate kinase PfkB family
GEV41_04425	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GEV41_04425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GEV41_04425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GEV41_04435	COG3530	Putative quorum-sensing-regulated virulence factor
GEV41_04445	COG4251	negative regulation of phosphorylation
GEV41_04445	COG3706	GGDEF domain
GEV41_04445	COG2203	Gaf domain
GEV41_04445	COG5001	Diguanylate cyclase
GEV41_04495	COG3604	Transcriptional regulator
GEV41_04500	COG1017	nitric oxide dioxygenase activity
GEV41_04500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GEV41_04505	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GEV41_04510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GEV41_04515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GEV41_04520	COG1845	cytochrome c oxidase, subunit III
GEV41_04525	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GEV41_04530	COG0109	protoheme IX farnesyltransferase activity
GEV41_04535	COG0436	Aminotransferase
GEV41_04545	COG0727	PFAM Uncharacterised protein family (UPF0153)
GEV41_04550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GEV41_04565	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GEV41_04570	COG0709	Synthesizes selenophosphate from selenide and ATP
GEV41_04575	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GEV41_04580	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GEV41_04585	COG3639	organic phosphonate transmembrane transporter activity
GEV41_04590	COG3639	organic phosphonate transmembrane transporter activity
GEV41_04595	COG3781	membrane
GEV41_04600	COG3657	addiction module killer protein
GEV41_04625	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GEV41_04630	COG0343	queuine tRNA-ribosyltransferase activity
GEV41_04635	COG1862	Preprotein translocase
GEV41_04650	COG3134	Outer membrane lipoprotein
GEV41_04670	COG1045	serine acetyltransferase
GEV41_04680	COG1104	cysteine desulfurase activity
GEV41_04690	COG0316	Belongs to the HesB IscA family
GEV41_04695	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GEV41_04700	COG0443	Heat shock 70 kDa protein
GEV41_04705	COG0633	Ferredoxin
GEV41_04715	COG0105	UTP biosynthetic process
GEV41_04720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GEV41_04735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GEV41_04740	COG0124	histidyl-tRNA synthetase
GEV41_04755	COG1160	GTP binding
GEV41_04760	COG0436	Aminotransferase
GEV41_04775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GEV41_04780	COG4774	siderophore transport
GEV41_04785	COG3128	pkhd-type hydroxylase
GEV41_04795	COG0019	diaminopimelate decarboxylase activity
GEV41_04810	COG4772	TonB-dependent receptor
GEV41_04840	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GEV41_04855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_04855	COG0723	plastoquinol--plastocyanin reductase activity
GEV41_04870	COG3436	PFAM IS66 Orf2 family protein
GEV41_04890	COG3209	COG3209 Rhs family protein
GEV41_04895	COG4608	Belongs to the ABC transporter superfamily
GEV41_04900	COG0444	Belongs to the ABC transporter superfamily
GEV41_04905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV41_04910	COG0601	transmembrane transport
GEV41_04915	COG0747	negative chemotaxis
GEV41_04930	COG0747	negative chemotaxis
GEV41_04945	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GEV41_04965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEV41_04970	COG0693	protein deglycase activity
GEV41_04985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GEV41_04985	COG3153	acetyltransferase
GEV41_05015	COG0642	Histidine kinase
GEV41_05025	COG3642	lipopolysaccharide core region biosynthetic process
GEV41_05035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GEV41_05040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GEV41_05090	COG3622	Belongs to the hyi family
GEV41_05095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GEV41_05105	COG0583	DNA-binding transcription factor activity
GEV41_05110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GEV41_05120	COG1902	pentaerythritol trinitrate reductase activity
GEV41_05155	COG1113	amino acid transport
GEV41_05170	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GEV41_05175	COG0154	amidase activity
GEV41_05180	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GEV41_05185	COG1077	Cell shape determining protein MreB Mrl
GEV41_05190	COG1792	Involved in formation and maintenance of cell shape
GEV41_05200	COG0424	maF-like protein
GEV41_05205	COG1530	ribonuclease E activity
GEV41_05215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GEV41_05220	COG0312	modulator of DNA gyrase
GEV41_05225	COG3028	Belongs to the UPF0307 family
GEV41_05230	COG0312	modulator of DNA gyrase
GEV41_05260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GEV41_05265	COG1660	Displays ATPase and GTPase activities
GEV41_05275	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GEV41_05280	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GEV41_05285	COG1137	ATPase activity
GEV41_05290	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GEV41_05300	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GEV41_05310	COG1127	ABC transporter
GEV41_05315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GEV41_05320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GEV41_05340	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GEV41_05345	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GEV41_05350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GEV41_05355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GEV41_05375	COG2186	Transcriptional regulator
GEV41_05380	COG2807	transmembrane transport
GEV41_05390	COG2827	Endonuclease containing a URI domain
GEV41_05395	COG3081	Nucleoid-associated protein
GEV41_05400	COG0776	regulation of translation
GEV41_05405	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GEV41_05410	COG0525	valine-tRNA ligase activity
GEV41_05425	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GEV41_05435	COG0795	lipopolysaccharide-transporting ATPase activity
GEV41_05440	COG0795	lipopolysaccharide-transporting ATPase activity
GEV41_05450	COG1278	Cold shock
GEV41_05455	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GEV41_05460	COG1760	l-serine dehydratase
GEV41_05465	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GEV41_05465	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GEV41_05470	COG0509	glycine decarboxylation via glycine cleavage system
GEV41_05485	COG3220	belongs to the UPF0276 family
GEV41_05495	COG1595	DNA-templated transcription, initiation
GEV41_05500	COG4944	Protein of unknown function (DUF1109)
GEV41_05505	COG0786	glutamate:sodium symporter activity
GEV41_05530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GEV41_05535	COG2235	arginine
GEV41_05550	COG2832	Protein of unknown function (DUF454)
GEV41_05560	COG1629	transport
GEV41_05560	COG4771	TonB-dependent receptor
GEV41_05590	COG0745	RESPONSE REGULATOR receiver
GEV41_05610	COG1175	transmembrane transport
GEV41_05620	COG3842	ATPase activity
GEV41_05630	COG0676	glucose-6-phosphate 1-epimerase activity
GEV41_05635	COG1737	Transcriptional regulator
GEV41_05650	COG0800	Aldolase
GEV41_05655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GEV41_05665	COG0739	heme binding
GEV41_05670	COG1570	exodeoxyribonuclease VII activity
GEV41_05690	COG0583	DNA-binding transcription factor activity
GEV41_05710	COG0519	Catalyzes the synthesis of GMP from XMP
GEV41_05710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GEV41_05735	COG4691	Plasmid stability protein
GEV41_05770	COG0798	PFAM Bile acid sodium symporter
GEV41_05810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GEV41_05835	COG0590	tRNA wobble adenosine to inosine editing
GEV41_05840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GEV41_05855	COG0047	phosphoribosylformylglycinamidine synthase activity
GEV41_05855	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GEV41_05870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GEV41_05875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GEV41_05880	COG3156	type II secretion system protein K
GEV41_05910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GEV41_05955	COG2375	cellular response to nickel ion
GEV41_05960	COG1695	Transcriptional regulator
GEV41_05970	COG1113	amino acid transport
GEV41_05975	COG0069	glutamate synthase activity
GEV41_05985	COG0494	nUDIX hydrolase
GEV41_05990	COG0583	DNA-binding transcription factor activity
GEV41_05995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GEV41_06015	COG1126	abc transporter atp-binding protein
GEV41_06020	COG0765	amino acid transport
GEV41_06025	COG0765	amino acid transport
GEV41_06050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GEV41_06060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GEV41_06065	COG3842	ATPase activity
GEV41_06070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GEV41_06075	COG0243	molybdopterin cofactor binding
GEV41_06080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GEV41_06100	COG0450	alkyl hydroperoxide reductase
GEV41_06105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GEV41_06110	COG0418	dihydroorotase activity
GEV41_06130	COG0137	argininosuccinate synthase activity
GEV41_06140	COG2197	response regulator
GEV41_06145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GEV41_06155	COG4659	FMN binding
GEV41_06170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GEV41_06170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GEV41_06175	COG0489	protein tyrosine kinase activity
GEV41_06180	COG1278	Cold shock
GEV41_06185	COG0717	Belongs to the dCTP deaminase family
GEV41_06200	COG1201	RNA secondary structure unwinding
GEV41_06210	COG1793	dna ligase
GEV41_06215	COG1793	dna ligase
GEV41_06215	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GEV41_06220	COG2366	antibiotic biosynthetic process
GEV41_06225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GEV41_06230	COG1045	serine acetyltransferase
GEV41_06235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GEV41_06240	COG2814	Major facilitator Superfamily
GEV41_06255	COG0653	protein targeting
GEV41_06265	COG3012	SEC-C Motif Domain Protein
GEV41_06295	COG1199	ATP-dependent helicase activity
GEV41_06315	COG0259	pyridoxamine-phosphate oxidase activity
GEV41_06330	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GEV41_06335	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GEV41_06380	COG2084	Dehydrogenase
GEV41_06390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GEV41_06405	COG1289	transmembrane transporter activity
GEV41_06425	COG5001	Diguanylate cyclase
GEV41_06425	COG3300	MHYT domain
GEV41_06430	COG3706	GGDEF domain
GEV41_06435	COG2116	formate transmembrane transporter activity
GEV41_06475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GEV41_06485	COG0252	asparaginase activity
GEV41_06490	COG3012	SEC-C Motif Domain Protein
GEV41_06490	COG3318	Belongs to the UPF0149 family
GEV41_06495	COG0625	glutathione transferase activity
GEV41_06505	COG0583	DNA-binding transcription factor activity
GEV41_06530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GEV41_06540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GEV41_06555	COG3077	Addiction module antitoxin, RelB DinJ family
GEV41_06565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GEV41_06570	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GEV41_06570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GEV41_06575	COG0745	RESPONSE REGULATOR receiver
GEV41_06580	COG2205	protein histidine kinase activity
GEV41_06600	COG0745	RESPONSE REGULATOR receiver
GEV41_06605	COG2205	protein histidine kinase activity
GEV41_06615	COG1301	dicarboxylic acid transport
GEV41_06625	COG4807	Protein conserved in bacteria
GEV41_06635	COG0519	Catalyzes the synthesis of GMP from XMP
GEV41_06665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GEV41_06670	COG3158	transport of potassium into the cell
GEV41_06700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GEV41_06710	COG0442	prolyl-tRNA aminoacylation
GEV41_06725	COG2900	Belongs to the SlyX family
GEV41_06735	COG0783	Belongs to the Dps family
GEV41_06740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GEV41_06755	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GEV41_06760	COG0217	transcriptional regulatory protein
GEV41_06765	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GEV41_06770	COG0632	four-way junction helicase activity
GEV41_06775	COG2255	four-way junction helicase activity
GEV41_06780	COG0824	Thioesterase
GEV41_06800	COG0823	Involved in the tonB-independent uptake of proteins
GEV41_06805	COG2885	chlorophyll binding
GEV41_06810	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GEV41_06815	COG0602	queuosine metabolic process
GEV41_06820	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GEV41_06830	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GEV41_06850	COG3609	addiction module antidote protein, CC2985 family
GEV41_06950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GEV41_06975	COG3039	Transposase
GEV41_06985	COG4644	lycopene metabolic process
GEV41_07070	COG1074	ATP-dependent DNA helicase activity
GEV41_07110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GEV41_07245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GEV41_07255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GEV41_07310	COG3081	Nucleoid-associated protein
GEV41_07330	COG0305	Participates in initiation and elongation during chromosome replication
GEV41_07360	COG0840	transmembrane signaling receptor activity
GEV41_07365	COG0531	amino acid
GEV41_07370	COG5339	Protein conserved in bacteria
GEV41_07375	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GEV41_07385	COG0425	Belongs to the sulfur carrier protein TusA family
GEV41_07395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GEV41_07405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEV41_07410	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GEV41_07415	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GEV41_07420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GEV41_07515	COG0579	oxidoreductase
GEV41_07520	COG0640	Transcriptional regulator
GEV41_07525	COG1902	pentaerythritol trinitrate reductase activity
GEV41_07540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEV41_07545	COG3938	Belongs to the proline racemase family
GEV41_07550	COG0531	amino acid
GEV41_07565	COG0521	Mo-molybdopterin cofactor biosynthetic process
GEV41_07570	COG3781	membrane
GEV41_07575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GEV41_07585	COG1522	sequence-specific DNA binding
GEV41_07590	COG0626	cystathionine gamma-synthase activity
GEV41_07605	COG2194	sulfuric ester hydrolase activity
GEV41_07615	COG3100	YcgL domain-containing protein
GEV41_07630	COG2983	Belongs to the UPF0260 family
GEV41_07675	COG0121	glutamine amidotransferase
GEV41_07690	COG2814	Major facilitator Superfamily
GEV41_07695	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GEV41_07700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GEV41_07705	COG1984	allophanate hydrolase subunit 2
GEV41_07725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GEV41_07750	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GEV41_07775	COG1295	ribonuclease BN
GEV41_07780	COG0242	peptide deformylase activity
GEV41_07800	COG3795	YCII-related domain
GEV41_07810	COG4941	Belongs to the sigma-70 factor family
GEV41_07815	COG2030	dehydratase
GEV41_07820	COG2267	carboxylic ester hydrolase activity
GEV41_07825	COG0318	PFAM AMP-dependent synthetase and ligase
GEV41_07830	COG0318	PFAM AMP-dependent synthetase and ligase
GEV41_07835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_07840	COG0174	glutamine synthetase
GEV41_07845	COG1643	Atp-dependent helicase
GEV41_07855	COG2188	Transcriptional regulator
GEV41_07865	COG1132	(ABC) transporter
GEV41_07875	COG2267	carboxylic ester hydrolase activity
GEV41_07890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GEV41_07900	COG0668	transmembrane transport
GEV41_07905	COG0513	Belongs to the DEAD box helicase family
GEV41_07940	COG0583	DNA-binding transcription factor activity
GEV41_07960	COG0840	transmembrane signaling receptor activity
GEV41_07975	COG2832	Protein of unknown function (DUF454)
GEV41_07990	COG0514	ATP-dependent DNA helicase (RecQ)
GEV41_08000	COG1752	Esterase of the alpha-beta hydrolase superfamily
GEV41_08015	COG2207	Transcriptional regulator
GEV41_08035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GEV41_08040	COG0778	Nitroreductase
GEV41_08055	COG0745	RESPONSE REGULATOR receiver
GEV41_08070	COG2350	Protein conserved in bacteria
GEV41_08075	COG2917	probably involved in intracellular septation
GEV41_08080	COG0613	PHP domain protein
GEV41_08085	COG0009	L-threonylcarbamoyladenylate synthase
GEV41_08095	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GEV41_08105	COG1113	amino acid transport
GEV41_08115	COG0247	lactate metabolic process
GEV41_08115	COG0277	FAD linked oxidase domain protein
GEV41_08130	COG2154	pterin-4-alpha-carbinolamine dehydratase
GEV41_08155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GEV41_08160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV41_08165	COG4215	(ABC) transporter
GEV41_08190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GEV41_08205	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_08210	COG3724	N-succinylarginine dihydrolase activity
GEV41_08220	COG2988	succinylglutamate desuccinylase activity
GEV41_08225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GEV41_08230	COG0527	aspartate kinase activity
GEV41_08235	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GEV41_08270	COG2239	Acts as a magnesium transporter
GEV41_08295	COG1113	amino acid transport
GEV41_08305	COG3706	GGDEF domain
GEV41_08310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GEV41_08320	COG0022	dehydrogenase e1 component
GEV41_08325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GEV41_08330	COG1522	sequence-specific DNA binding
GEV41_08340	COG0477	Major facilitator Superfamily
GEV41_08345	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GEV41_08365	COG0835	chemotaxis
GEV41_08365	COG0784	Response regulator, receiver
GEV41_08370	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GEV41_08375	COG1815	bacterial-type flagellum-dependent cell motility
GEV41_08385	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GEV41_08410	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GEV41_08415	COG1706	bacterial-type flagellum-dependent cell motility
GEV41_08425	COG1256	bacterial-type flagellum assembly
GEV41_08425	COG4786	Flagellar basal body rod
GEV41_08435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GEV41_08445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GEV41_08455	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GEV41_08480	COG3852	Histidine kinase
GEV41_08495	COG1677	Flagellar hook-basal body complex protein FliE
GEV41_08520	COG2882	bacterial-type flagellum organization
GEV41_08535	COG0745	RESPONSE REGULATOR receiver
GEV41_08580	COG1987	bacterial-type flagellum assembly
GEV41_08600	COG1181	Belongs to the D-alanine--D-alanine ligase family
GEV41_08605	COG1104	cysteine desulfurase activity
GEV41_08625	COG1181	Belongs to the D-alanine--D-alanine ligase family
GEV41_08630	COG1802	Transcriptional regulator
GEV41_08635	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GEV41_08660	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GEV41_08665	COG0643	Histidine kinase
GEV41_08665	COG2198	Histidine kinase
GEV41_08665	COG0784	Response regulator, receiver
GEV41_08670	COG2201	protein-glutamate methylesterase activity
GEV41_08675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GEV41_08680	COG1360	Flagellar Motor Protein
GEV41_08685	COG1192	Involved in chromosome partitioning
GEV41_08695	COG0835	chemotaxis
GEV41_08710	COG2257	FlhB HrpN YscU SpaS Family
GEV41_08720	COG4133	protoheme IX ABC transporter activity
GEV41_08740	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GEV41_08745	COG1138	Cytochrome C-type biogenesis protein
GEV41_08775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEV41_08810	COG1953	Uracil, thiamine, allantoin
GEV41_08815	COG1522	sequence-specific DNA binding
GEV41_08825	COG0116	Belongs to the methyltransferase superfamily
GEV41_08825	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GEV41_08835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GEV41_08845	COG0469	pyruvate kinase activity
GEV41_08855	COG2084	Dehydrogenase
GEV41_08860	COG3622	Belongs to the hyi family
GEV41_08865	COG3960	tartronate-semialdehyde synthase activity
GEV41_08885	COG2354	Protein conserved in bacteria
GEV41_08890	COG1368	sulfuric ester hydrolase activity
GEV41_08905	COG2233	PERMEase
GEV41_08915	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GEV41_08940	COG2252	PERMEase
GEV41_08950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GEV41_08955	COG0402	S-adenosylhomocysteine deaminase activity
GEV41_08985	COG3115	cell septum assembly
GEV41_08990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GEV41_09000	COG0789	Transcriptional regulator
GEV41_09020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GEV41_09025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GEV41_09030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GEV41_09035	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GEV41_09040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GEV41_09060	COG2217	Heavy metal translocating P-type atpase
GEV41_09070	COG0348	domain, Protein
GEV41_09075	COG2010	Cytochrome c
GEV41_09090	COG3278	Belongs to the heme-copper respiratory oxidase family
GEV41_09110	COG2010	Cytochrome c
GEV41_09125	COG3278	Belongs to the heme-copper respiratory oxidase family
GEV41_09135	COG3123	guanosine phosphorylase activity
GEV41_09170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GEV41_09205	COG3608	succinylglutamate desuccinylase aspartoacylase
GEV41_09205	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GEV41_09210	COG2068	MobA-Related Protein
GEV41_09235	COG0642	Histidine kinase
GEV41_09275	COG0477	Major facilitator Superfamily
GEV41_09285	COG2944	sequence-specific DNA binding
GEV41_09315	COG2885	chlorophyll binding
GEV41_09320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GEV41_09345	COG2009	succinate dehydrogenase
GEV41_09350	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GEV41_09355	COG1053	succinate dehydrogenase
GEV41_09375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GEV41_09380	COG0045	succinate-CoA ligase (ADP-forming) activity
GEV41_09440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GEV41_09460	COG1136	(ABC) transporter
GEV41_09460	COG0577	efflux transmembrane transporter activity
GEV41_09465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GEV41_09485	COG0326	Molecular chaperone. Has ATPase activity
GEV41_09495	COG1741	Belongs to the pirin family
GEV41_09510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GEV41_09515	COG4999	Histidine kinase
GEV41_09515	COG2205	protein histidine kinase activity
GEV41_09515	COG3850	Histidine kinase
GEV41_09515	COG3437	response regulator, receiver
GEV41_09530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GEV41_09565	COG0628	permease
GEV41_09580	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GEV41_09590	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GEV41_09595	COG2205	protein histidine kinase activity
GEV41_09600	COG0745	RESPONSE REGULATOR receiver
GEV41_09605	COG0583	DNA-binding transcription factor activity
GEV41_09615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GEV41_09620	COG1569	PIN domain
GEV41_09625	COG3311	Transcriptional regulator
GEV41_09630	COG4172	Belongs to the ABC transporter superfamily
GEV41_09635	COG4239	(ABC) transporter, permease
GEV41_09640	COG4174	ABC transporter (Permease)
GEV41_09645	COG4166	transmembrane transport
GEV41_09650	COG4166	transmembrane transport
GEV41_09655	COG0741	lytic transglycosylase activity
GEV41_09655	COG1388	LysM domain
GEV41_09660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GEV41_09670	COG0328	RNA-DNA hybrid ribonuclease activity
GEV41_09685	COG1982	Orn Lys Arg decarboxylase major
GEV41_09695	COG0431	NADPH-dependent FMN reductase
GEV41_09730	COG1007	ATP synthesis coupled electron transport
GEV41_09745	COG0713	ATP synthesis coupled electron transport
GEV41_09755	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV41_09760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GEV41_09765	COG1034	ATP synthesis coupled electron transport
GEV41_09780	COG0649	NAD binding
GEV41_09780	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV41_09785	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV41_09790	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV41_09825	COG0659	secondary active sulfate transmembrane transporter activity
GEV41_09835	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GEV41_09850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GEV41_09855	COG0583	DNA-binding transcription factor activity
GEV41_09860	COG1113	amino acid transport
GEV41_09865	COG2050	protein possibly involved in aromatic compounds catabolism
GEV41_09865	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GEV41_09870	COG0625	glutathione transferase activity
GEV41_09880	COG0306	phosphate transporter
GEV41_09905	COG0322	excinuclease ABC activity
GEV41_09945	COG3436	PFAM IS66 Orf2 family protein
GEV41_09975	COG3501	Rhs element vgr protein
GEV41_10065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GEV41_10085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GEV41_10090	COG1960	acyl-CoA dehydrogenase activity
GEV41_10100	COG0318	PFAM AMP-dependent synthetase and ligase
GEV41_10125	COG0366	Alpha amylase catalytic
GEV41_10130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GEV41_10140	COG3568	Endonuclease Exonuclease Phosphatase
GEV41_10160	COG1640	4-alpha-glucanotransferase
GEV41_10165	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GEV41_10170	COG0297	glycogen (starch) synthase activity
GEV41_10175	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GEV41_10180	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GEV41_10185	COG3387	PFAM Glycoside hydrolase 15-related
GEV41_10195	COG1309	transcriptional regulator
GEV41_10210	COG0493	'glutamate synthase
GEV41_10220	COG1953	Uracil, thiamine, allantoin
GEV41_10230	COG1234	tRNA 3'-trailer cleavage
GEV41_10235	COG3040	lipid binding
GEV41_10240	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GEV41_10245	COG1024	Enoyl-CoA hydratase
GEV41_10250	COG2816	NAD+ diphosphatase activity
GEV41_10270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_10280	COG2153	protein acetylation
GEV41_10285	COG2850	peptidyl-arginine hydroxylation
GEV41_10295	COG2915	High frequency lysogenization protein hflD homolog
GEV41_10300	COG0482	sulfurtransferase activity
GEV41_10320	COG1278	Cold shock
GEV41_10325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GEV41_10330	COG0542	response to heat
GEV41_10335	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GEV41_10340	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GEV41_10345	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GEV41_10350	COG1674	ftsk spoiiie
GEV41_10355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GEV41_10360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GEV41_10365	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GEV41_10370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GEV41_10375	COG1648	precorrin-2 dehydrogenase activity
GEV41_10375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GEV41_10380	COG0435	Glutathione S-transferase
GEV41_10385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GEV41_10390	COG2920	part of a sulfur-relay system
GEV41_10410	COG2233	PERMEase
GEV41_10430	COG2814	Major facilitator Superfamily
GEV41_10445	COG3485	protocatechuate 3,4-dioxygenase
GEV41_10450	COG0583	DNA-binding transcription factor activity
GEV41_10465	COG0583	DNA-binding transcription factor activity
GEV41_10475	COG0673	inositol 2-dehydrogenase activity
GEV41_10480	COG0673	inositol 2-dehydrogenase activity
GEV41_10485	COG4213	ABC transporter substrate-binding protein
GEV41_10495	COG4214	carbohydrate transport
GEV41_10515	COG0154	amidase activity
GEV41_10530	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_10535	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_10545	COG0523	cobalamin synthesis protein
GEV41_10560	COG0251	oxidation-reduction process
GEV41_10570	COG0477	Major facilitator Superfamily
GEV41_10585	COG0235	Class ii aldolase
GEV41_10590	COG0477	Major facilitator Superfamily
GEV41_10595	COG0583	DNA-binding transcription factor activity
GEV41_10605	COG1113	amino acid transport
GEV41_10615	COG2423	ornithine cyclodeaminase activity
GEV41_10645	COG0583	DNA-binding transcription factor activity
GEV41_10650	COG1522	sequence-specific DNA binding
GEV41_10665	COG0446	pyridine nucleotide-disulphide oxidoreductase
GEV41_10665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GEV41_10680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GEV41_10700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GEV41_10705	COG2218	PFAM glutamate synthase alpha subunit domain protein
GEV41_10710	COG0069	glutamate synthase activity
GEV41_10720	COG0004	ammonium transporteR
GEV41_10730	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GEV41_10735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GEV41_10740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GEV41_10755	COG1309	transcriptional regulator
GEV41_10760	COG2010	Cytochrome c
GEV41_10760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GEV41_10765	COG2080	2 iron, 2 sulfur cluster binding
GEV41_10775	COG1846	Transcriptional regulator
GEV41_10780	COG2309	aminopeptidase activity
GEV41_10785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GEV41_10790	COG0596	Alpha beta hydrolase
GEV41_10795	COG3473	Maleate cis-trans isomerase
GEV41_10800	COG1335	isochorismatase
GEV41_10805	COG2271	Major facilitator Superfamily
GEV41_10835	COG2199	diguanylate cyclase activity
GEV41_10840	COG0490	domain, Protein
GEV41_10840	COG0471	metal ion transport
GEV41_10865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GEV41_10870	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_10890	COG0616	signal peptide processing
GEV41_10950	COG0270	DNA (cytosine-5-)-methyltransferase activity
GEV41_10975	COG5532	Uncharacterized conserved protein (DUF2303)
GEV41_11090	COG0616	signal peptide processing
GEV41_11130	COG4386	tail sheath protein
GEV41_11175	COG3299	homolog of phage Mu protein gp47
GEV41_11355	COG3081	Nucleoid-associated protein
GEV41_11485	COG4695	Portal protein
GEV41_11490	COG0740	serine-type endopeptidase activity
GEV41_11605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GEV41_11640	COG1090	epimerase
GEV41_11660	COG1064	alcohol dehydrogenase
GEV41_11670	COG2259	Doxx family
GEV41_11680	COG0784	Response regulator, receiver
GEV41_11680	COG4191	Histidine kinase
GEV41_11685	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GEV41_11690	COG0745	RESPONSE REGULATOR receiver
GEV41_11695	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GEV41_11705	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GEV41_11735	COG2863	cytochrome
GEV41_11740	COG3258	Cytochrome c
GEV41_11760	COG3842	ATPase activity
GEV41_11765	COG1177	transmembrane transport
GEV41_11770	COG1176	ABC-type spermidine putrescine transport system, permease component I
GEV41_11780	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GEV41_11800	COG0583	DNA-binding transcription factor activity
GEV41_11840	COG1121	(ABC) transporter
GEV41_11880	COG1686	Belongs to the peptidase S11 family
GEV41_11915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GEV41_11950	COG2198	Histidine kinase
GEV41_11950	COG0784	Response regulator, receiver
GEV41_11950	COG2205	protein histidine kinase activity
GEV41_11955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GEV41_11970	COG2198	Histidine kinase
GEV41_11970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV41_11970	COG0784	Response regulator, receiver
GEV41_11970	COG2205	protein histidine kinase activity
GEV41_11980	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV41_11985	COG0183	Belongs to the thiolase family
GEV41_11995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GEV41_12000	COG2807	transmembrane transport
GEV41_12015	COG3193	protein, possibly involved in utilization of glycolate and propanediol
GEV41_12020	COG0247	lactate metabolic process
GEV41_12025	COG0277	FAD linked oxidase domain protein
GEV41_12030	COG0277	FAD linked oxidase domain protein
GEV41_12035	COG2186	Transcriptional regulator
GEV41_12050	COG0768	penicillin binding
GEV41_12085	COG4181	ATPase activity
GEV41_12100	COG1024	Enoyl-CoA hydratase
GEV41_12125	COG0833	amino acid
GEV41_12130	COG1024	Enoyl-CoA hydratase
GEV41_12135	COG1960	acyl-CoA dehydrogenase activity
GEV41_12150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GEV41_12165	COG2249	NAD(P)H dehydrogenase (quinone) activity
GEV41_12185	COG3192	ethanolamine utilization protein
GEV41_12215	COG4948	Mandelate Racemase Muconate Lactonizing
GEV41_12220	COG4829	muconolactone delta-isomerase
GEV41_12225	COG3485	protocatechuate 3,4-dioxygenase
GEV41_12235	COG5001	Diguanylate cyclase
GEV41_12240	COG0656	L-ascorbic acid biosynthetic process
GEV41_12255	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GEV41_12265	COG0477	Major facilitator Superfamily
GEV41_12275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEV41_12280	COG5001	Diguanylate cyclase
GEV41_12280	COG3300	MHYT domain
GEV41_12285	COG1611	Belongs to the LOG family
GEV41_12290	COG2855	membrane
GEV41_12300	COG2030	dehydratase
GEV41_12310	COG2814	Major facilitator Superfamily
GEV41_12325	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GEV41_12340	COG1280	lysine exporter protein (LysE YggA)
GEV41_12345	COG4191	Histidine kinase
GEV41_12345	COG0784	Response regulator, receiver
GEV41_12350	COG2816	NAD+ diphosphatase activity
GEV41_12355	COG2186	Transcriptional regulator
GEV41_12360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GEV41_12370	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_12375	COG2267	carboxylic ester hydrolase activity
GEV41_12385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV41_12395	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GEV41_12410	COG1959	2 iron, 2 sulfur cluster binding
GEV41_12415	COG2207	Transcriptional regulator
GEV41_12435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GEV41_12440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GEV41_12450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GEV41_12460	COG4991	sh3 domain protein
GEV41_12475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GEV41_12515	COG1944	ATP diphosphatase activity
GEV41_12535	COG3501	Rhs element vgr protein
GEV41_12605	COG1132	(ABC) transporter
GEV41_12625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEV41_12630	COG0454	-acetyltransferase
GEV41_12685	COG1522	sequence-specific DNA binding
GEV41_12700	COG2271	Major facilitator Superfamily
GEV41_12730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GEV41_12740	COG0581	inorganic phosphate transmembrane transporter activity
GEV41_12745	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GEV41_12770	COG0784	Response regulator, receiver
GEV41_12770	COG2205	protein histidine kinase activity
GEV41_12810	COG1131	(ABC) transporter
GEV41_12845	COG2010	Cytochrome c
GEV41_12845	COG4993	Dehydrogenase
GEV41_12870	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_12895	COG0784	Response regulator, receiver
GEV41_12895	COG5002	protein histidine kinase activity
GEV41_12895	COG2205	protein histidine kinase activity
GEV41_12900	COG0583	DNA-binding transcription factor activity
GEV41_12905	COG3048	D-serine ammonia-lyase activity
GEV41_12910	COG2610	gluconate transmembrane transporter activity
GEV41_12920	COG1305	Transglutaminase-like
GEV41_12930	COG2308	Evidence 4 Homologs of previously reported genes of
GEV41_12950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GEV41_12960	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_12970	COG0583	DNA-binding transcription factor activity
GEV41_12975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GEV41_12990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GEV41_12990	COG0678	peroxiredoxin activity
GEV41_12995	COG0583	DNA-binding transcription factor activity
GEV41_13010	COG1473	amidohydrolase
GEV41_13025	COG0708	Exodeoxyribonuclease III
GEV41_13055	COG0745	RESPONSE REGULATOR receiver
GEV41_13065	COG0431	NADPH-dependent FMN reductase
GEV41_13070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GEV41_13080	COG0640	Transcriptional regulator
GEV41_13095	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_13105	COG0693	protein deglycase activity
GEV41_13110	COG2323	membrane
GEV41_13140	COG3046	protein related to deoxyribodipyrimidine photolyase
GEV41_13155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GEV41_13170	COG4221	oxidoreductase activity
GEV41_13180	COG1366	Belongs to the anti-sigma-factor antagonist family
GEV41_13185	COG0789	Transcriptional regulator
GEV41_13190	COG0668	transmembrane transport
GEV41_13210	COG0589	response to stress
GEV41_13280	COG1129	ABC transporter
GEV41_13285	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV41_13290	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV41_13295	COG1960	acyl-CoA dehydrogenase activity
GEV41_13300	COG0431	NADPH-dependent FMN reductase
GEV41_13325	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV41_13335	COG3829	transcription factor binding
GEV41_13345	COG4175	Glycine betaine
GEV41_13350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV41_13355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GEV41_13365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GEV41_13410	COG2249	NAD(P)H dehydrogenase (quinone) activity
GEV41_13415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GEV41_13440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GEV41_13460	COG0604	alcohol dehydrogenase
GEV41_13460	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_13460	COG3321	synthase
GEV41_13485	COG4948	Mandelate Racemase Muconate Lactonizing
GEV41_13495	COG0582	viral genome integration into host DNA
GEV41_13505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GEV41_13730	COG3567	Phage-associated protein, HI1409 family
GEV41_13735	COG2369	cell adhesion
GEV41_13850	COG3728	DNA packaging
GEV41_13855	COG5410	chromosome segregation
GEV41_13895	COG0583	DNA-binding transcription factor activity
GEV41_13900	COG2721	sulfolactate sulfo-lyase activity
GEV41_13915	COG2271	Major facilitator Superfamily
GEV41_13925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GEV41_13925	COG1199	ATP-dependent helicase activity
GEV41_13935	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GEV41_13940	COG0829	nickel cation binding
GEV41_13945	COG0831	urea catabolic process
GEV41_13950	COG0832	Belongs to the urease beta subunit family
GEV41_13955	COG0804	urea catabolic process
GEV41_13960	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GEV41_13970	COG0830	nickel cation binding
GEV41_13975	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GEV41_14035	COG0840	transmembrane signaling receptor activity
GEV41_14040	COG1968	undecaprenyl-diphosphatase activity
GEV41_14060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GEV41_14065	COG1252	NADH dehydrogenase
GEV41_14075	COG1902	pentaerythritol trinitrate reductase activity
GEV41_14075	COG0446	pyridine nucleotide-disulphide oxidoreductase
GEV41_14085	COG0235	Class ii aldolase
GEV41_14095	COG0393	Putative heavy-metal-binding
GEV41_14125	COG0746	molybdenum cofactor guanylyltransferase activity
GEV41_14135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GEV41_14140	COG0745	RESPONSE REGULATOR receiver
GEV41_14145	COG2205	protein histidine kinase activity
GEV41_14155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GEV41_14195	COG1253	flavin adenine dinucleotide binding
GEV41_14205	COG2200	EAL domain
GEV41_14225	COG0784	Response regulator, receiver
GEV41_14225	COG4191	Histidine kinase
GEV41_14250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GEV41_14255	COG1459	type II secretion system
GEV41_14265	COG1196	nuclear chromosome segregation
GEV41_14265	COG0739	heme binding
GEV41_14265	COG0741	lytic transglycosylase activity
GEV41_14270	COG5002	protein histidine kinase activity
GEV41_14280	COG2205	protein histidine kinase activity
GEV41_14285	COG2204	response regulator
GEV41_14300	COG3265	gluconokinase activity
GEV41_14305	COG1609	Transcriptional regulator
GEV41_14315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV41_14315	COG2205	protein histidine kinase activity
GEV41_14320	COG2197	response regulator
GEV41_14325	COG3813	Protein conserved in bacteria
GEV41_14420	COG3501	Rhs element vgr protein
GEV41_14455	COG1609	Transcriptional regulator
GEV41_14465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEV41_14470	COG2271	Major facilitator Superfamily
GEV41_14480	COG2356	endonuclease I
GEV41_14490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GEV41_14495	COG0745	RESPONSE REGULATOR receiver
GEV41_14500	COG2205	protein histidine kinase activity
GEV41_14505	COG0667	Aldo Keto reductase
GEV41_14515	COG2814	Major facilitator Superfamily
GEV41_14540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GEV41_14550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GEV41_14555	COG0668	transmembrane transport
GEV41_14560	COG3706	GGDEF domain
GEV41_14605	COG1301	dicarboxylic acid transport
GEV41_14620	COG1469	GTP cyclohydrolase I activity
GEV41_14650	COG0531	amino acid
GEV41_14690	COG0583	DNA-binding transcription factor activity
GEV41_14695	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_14740	COG0589	response to stress
GEV41_14760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GEV41_14770	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GEV41_14780	COG0071	Belongs to the small heat shock protein (HSP20) family
GEV41_14815	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GEV41_14840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GEV41_14850	COG3327	negative regulation of DNA-templated transcription, initiation
GEV41_14860	COG1024	Enoyl-CoA hydratase
GEV41_14865	COG1024	Enoyl-CoA hydratase
GEV41_14870	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV41_14875	COG2050	protein possibly involved in aromatic compounds catabolism
GEV41_14880	COG0183	Belongs to the thiolase family
GEV41_14890	COG3396	Phenylacetate-CoA oxygenase
GEV41_14895	COG3460	Phenylacetate-CoA oxygenase
GEV41_14900	COG3396	Phenylacetate-CoA oxygenase
GEV41_14905	COG2151	metal-sulfur cluster biosynthetic enzyme
GEV41_14910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GEV41_14915	COG3162	membrane
GEV41_14930	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_14930	COG2030	dehydratase
GEV41_14945	COG0494	nUDIX hydrolase
GEV41_14960	COG3568	Endonuclease Exonuclease Phosphatase
GEV41_14965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEV41_14970	COG0392	lysyltransferase activity
GEV41_15000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GEV41_15025	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GEV41_15055	COG0667	Aldo Keto reductase
GEV41_15060	COG2837	iron assimilation
GEV41_15065	COG0385	Bile acid
GEV41_15075	COG1285	pathogenesis
GEV41_15085	COG4251	negative regulation of phosphorylation
GEV41_15085	COG3706	GGDEF domain
GEV41_15085	COG5001	Diguanylate cyclase
GEV41_15085	COG2203	Gaf domain
GEV41_15105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GEV41_15110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GEV41_15115	COG0583	DNA-binding transcription factor activity
GEV41_15120	COG1960	acyl-CoA dehydrogenase activity
GEV41_15125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GEV41_15130	COG0235	Class ii aldolase
GEV41_15135	COG0747	negative chemotaxis
GEV41_15140	COG0601	transmembrane transport
GEV41_15155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV41_15160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV41_15185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GEV41_15200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GEV41_15220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GEV41_15225	COG2423	ornithine cyclodeaminase activity
GEV41_15230	COG0402	S-adenosylhomocysteine deaminase activity
GEV41_15240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GEV41_15245	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GEV41_15260	COG1999	signal sequence binding
GEV41_15280	COG0583	DNA-binding transcription factor activity
GEV41_15285	COG1929	Belongs to the glycerate kinase type-1 family
GEV41_15290	COG3835	regulator
GEV41_15295	COG2271	Major facilitator Superfamily
GEV41_15300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GEV41_15305	COG0667	Aldo Keto reductase
GEV41_15310	COG1902	pentaerythritol trinitrate reductase activity
GEV41_15315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV41_15335	COG3135	benzoate transporter
GEV41_15340	COG3485	protocatechuate 3,4-dioxygenase
GEV41_15345	COG2814	Major facilitator Superfamily
GEV41_15395	COG2826	transposase and inactivated derivatives, IS30 family
GEV41_15430	COG0583	DNA-binding transcription factor activity
GEV41_15435	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_15450	COG0174	glutamine synthetase
GEV41_15460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_15470	COG1760	l-serine dehydratase
GEV41_15475	COG0583	DNA-binding transcription factor activity
GEV41_15490	COG1215	transferase activity, transferring glycosyl groups
GEV41_15500	COG2990	Protein conserved in bacteria
GEV41_15505	COG1215	transferase activity, transferring glycosyl groups
GEV41_15550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GEV41_15575	COG1396	sequence-specific DNA binding
GEV41_15580	COG2031	fatty acid transporter
GEV41_15590	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GEV41_15600	COG0656	L-ascorbic acid biosynthetic process
GEV41_15610	COG0587	DNA-directed DNA polymerase activity
GEV41_15625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GEV41_15630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GEV41_15650	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_15665	COG0154	amidase activity
GEV41_15675	COG1473	amidohydrolase
GEV41_15690	COG3209	COG3209 Rhs family protein
GEV41_15695	COG3436	PFAM IS66 Orf2 family protein
GEV41_15715	COG3209	COG3209 Rhs family protein
GEV41_15750	COG3501	Rhs element vgr protein
GEV41_15825	COG1397	ADP-ribosylglycohydrolase
GEV41_15935	COG1881	PFAM PEBP family protein
GEV41_15940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GEV41_15945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GEV41_15950	COG4166	transmembrane transport
GEV41_15955	COG4174	ABC transporter (Permease)
GEV41_15960	COG4239	(ABC) transporter, permease
GEV41_15965	COG3829	transcription factor binding
GEV41_15965	COG3290	protein histidine kinase activity
GEV41_15970	COG2610	gluconate transmembrane transporter activity
GEV41_15975	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_15980	COG4574	serine-type endopeptidase inhibitor activity
GEV41_15985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GEV41_15990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GEV41_16040	COG3179	chitinase
GEV41_16200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GEV41_16265	COG2826	transposase and inactivated derivatives, IS30 family
GEV41_16290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GEV41_16305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GEV41_16370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GEV41_16375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GEV41_16380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV41_16405	COG0667	Aldo Keto reductase
GEV41_16415	COG0667	Aldo Keto reductase
GEV41_16435	COG1073	alpha beta
GEV41_16455	COG0446	pyridine nucleotide-disulphide oxidoreductase
GEV41_16455	COG1902	pentaerythritol trinitrate reductase activity
GEV41_16490	COG0456	acetyltransferase
GEV41_16490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GEV41_16505	COG0583	DNA-binding transcription factor activity
GEV41_16530	COG0189	ligase activity
GEV41_16550	COG0583	DNA-binding transcription factor activity
GEV41_16565	COG0697	spore germination
GEV41_16570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GEV41_16575	COG0642	Histidine kinase
GEV41_16580	COG0745	RESPONSE REGULATOR receiver
GEV41_16595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GEV41_16600	COG1477	protein flavinylation
GEV41_16615	COG4191	Histidine kinase
GEV41_16615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV41_16625	COG1858	cytochrome C peroxidase
GEV41_16635	COG2135	peptidase activity
GEV41_16660	COG0488	(ABC) transporter
GEV41_16675	COG0625	glutathione transferase activity
GEV41_16695	COG0019	diaminopimelate decarboxylase activity
GEV41_16705	COG4106	trans-aconitate 2-methyltransferase activity
GEV41_16720	COG0463	Glycosyl transferase, family 2
GEV41_16730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GEV41_16745	COG1984	allophanate hydrolase subunit 2
GEV41_16755	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GEV41_16770	COG0307	riboflavin synthase, alpha
GEV41_16785	COG0113	porphobilinogen synthase activity
GEV41_16795	COG1113	amino acid transport
GEV41_16800	COG0579	oxidoreductase
GEV41_16810	COG1802	Transcriptional regulator
GEV41_16815	COG0745	RESPONSE REGULATOR receiver
GEV41_16820	COG2205	protein histidine kinase activity
GEV41_16825	COG0215	cysteine-tRNA ligase activity
GEV41_16830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GEV41_16840	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GEV41_16845	COG2366	antibiotic biosynthetic process
GEV41_16885	COG0729	surface antigen
GEV41_16895	COG0708	Exodeoxyribonuclease III
GEV41_16910	COG1595	DNA-templated transcription, initiation
GEV41_16920	COG3038	cytochrome b561
GEV41_16925	COG0477	Major facilitator Superfamily
GEV41_16930	COG1917	Cupin 2, conserved barrel domain protein
GEV41_16930	COG1396	sequence-specific DNA binding
GEV41_16945	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_16960	COG0318	PFAM AMP-dependent synthetase and ligase
GEV41_16985	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_17000	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_17005	COG1063	alcohol dehydrogenase
GEV41_17020	COG2814	Major facilitator Superfamily
GEV41_17035	COG1132	(ABC) transporter
GEV41_17040	COG3284	Transcriptional regulator
GEV41_17070	COG3501	Rhs element vgr protein
GEV41_17125	COG2165	general secretion pathway protein
GEV41_17130	COG2165	general secretion pathway protein
GEV41_17135	COG4796	Type ii and iii secretion system protein
GEV41_17165	COG2204	response regulator
GEV41_17205	COG1960	acyl-CoA dehydrogenase activity
GEV41_17220	COG2384	SAM-dependent methyltransferase
GEV41_17230	COG0826	peptidase U32
GEV41_17235	COG2204	response regulator
GEV41_17270	COG0488	(ABC) transporter
GEV41_17275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GEV41_17285	COG0583	DNA-binding transcription factor activity
GEV41_17290	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
GEV41_17310	COG3064	Membrane
GEV41_17355	COG1309	transcriptional regulator
GEV41_17365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GEV41_17375	COG3257	ureidoglycine aminohydrolase activity
GEV41_17385	COG1522	sequence-specific DNA binding
GEV41_17390	COG2423	ornithine cyclodeaminase activity
GEV41_17395	COG0583	DNA-binding transcription factor activity
GEV41_17400	COG0405	Gamma-glutamyltransferase
GEV41_17410	COG2207	Transcriptional regulator
GEV41_17415	COG0789	Transcriptional regulator
GEV41_17425	COG1285	pathogenesis
GEV41_17435	COG0348	domain, Protein
GEV41_17440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GEV41_17450	COG0784	Response regulator, receiver
GEV41_17450	COG4191	Histidine kinase
GEV41_17455	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_17470	COG2814	Major facilitator Superfamily
GEV41_17475	COG1566	PFAM secretion protein HlyD family protein
GEV41_17480	COG1846	Transcriptional regulator
GEV41_17485	COG4566	intracellular signal transduction
GEV41_17495	COG0318	PFAM AMP-dependent synthetase and ligase
GEV41_17500	COG1960	acyl-CoA dehydrogenase activity
GEV41_17510	COG2056	Na+-H+ antiporter family
GEV41_17520	COG0840	transmembrane signaling receptor activity
GEV41_17530	COG4176	ABC-type proline glycine betaine transport system permease component
GEV41_17535	COG0583	DNA-binding transcription factor activity
GEV41_17560	COG1280	lysine exporter protein (LysE YggA)
GEV41_17565	COG2814	Major facilitator Superfamily
GEV41_17570	COG0583	DNA-binding transcription factor activity
GEV41_17600	COG2072	flavoprotein involved in K transport
GEV41_17610	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_17625	COG4774	siderophore transport
GEV41_17630	COG3712	iron ion homeostasis
GEV41_17635	COG1595	DNA-templated transcription, initiation
GEV41_17685	COG2814	Major facilitator Superfamily
GEV41_17690	COG0814	amino acid
GEV41_17725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_17730	COG1126	abc transporter atp-binding protein
GEV41_17735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GEV41_17750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEV41_17755	COG2271	Major facilitator Superfamily
GEV41_17760	COG2721	sulfolactate sulfo-lyase activity
GEV41_17765	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_17770	COG2186	Transcriptional regulator
GEV41_17805	COG4335	DNA alkylation repair
GEV41_17855	COG1414	Transcriptional regulator
GEV41_17860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GEV41_17875	COG1053	succinate dehydrogenase
GEV41_17890	COG0673	inositol 2-dehydrogenase activity
GEV41_17905	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GEV41_17910	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_17925	COG0531	amino acid
GEV41_17930	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_17960	COG2194	sulfuric ester hydrolase activity
GEV41_17970	COG3008	intermembrane lipid transfer
GEV41_17975	COG2995	paraquat-inducible protein a
GEV41_17995	COG0346	lactoylglutathione lyase activity
GEV41_18010	COG0477	Major facilitator Superfamily
GEV41_18020	COG0596	Alpha beta hydrolase
GEV41_18030	COG0210	DNA helicase
GEV41_18075	COG0076	glutamate decarboxylase activity
GEV41_18080	COG0583	DNA-binding transcription factor activity
GEV41_18085	COG0217	transcriptional regulatory protein
GEV41_18090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_18100	COG0583	DNA-binding transcription factor activity
GEV41_18110	COG4106	trans-aconitate 2-methyltransferase activity
GEV41_18125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GEV41_18165	COG0625	glutathione transferase activity
GEV41_18170	COG2814	Major facilitator Superfamily
GEV41_18175	COG0583	DNA-binding transcription factor activity
GEV41_18180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEV41_18195	COG2873	o-acetylhomoserine
GEV41_18215	COG1418	mRNA catabolic process
GEV41_18225	COG2066	Belongs to the glutaminase family
GEV41_18235	COG3384	dioxygenase
GEV41_18245	COG0583	DNA-binding transcription factor activity
GEV41_18250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GEV41_18255	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GEV41_18260	COG2828	Protein conserved in bacteria
GEV41_18270	COG0302	gtp cyclohydrolase
GEV41_18340	COG0776	regulation of translation
GEV41_18345	COG0072	phenylalanine-tRNA ligase activity
GEV41_18350	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GEV41_18355	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GEV41_18360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GEV41_18365	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GEV41_18370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GEV41_18380	COG1278	Cold shock
GEV41_18400	COG1869	D-ribose catabolic process
GEV41_18405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEV41_18410	COG1609	Transcriptional regulator
GEV41_18415	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV41_18420	COG1129	ABC transporter
GEV41_18430	COG0252	asparaginase activity
GEV41_18435	COG3604	Transcriptional regulator
GEV41_18440	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GEV41_18445	COG2116	formate transmembrane transporter activity
GEV41_18460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GEV41_18480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_18490	COG1253	flavin adenine dinucleotide binding
GEV41_18500	COG0583	DNA-binding transcription factor activity
GEV41_18505	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GEV41_18510	COG3132	Protein of unknown function, DUF480
GEV41_18530	COG3634	alkyl hydroperoxide reductase activity
GEV41_18540	COG0861	Integral membrane protein TerC family
GEV41_18565	COG1104	cysteine desulfurase activity
GEV41_18570	COG5654	RES domain protein
GEV41_18575	COG5642	Protein of unknown function (DUF2384)
GEV41_18585	COG0583	DNA-binding transcription factor activity
GEV41_18600	COG2814	Major facilitator Superfamily
GEV41_18615	COG1064	alcohol dehydrogenase
GEV41_18620	COG2207	Transcriptional regulator
GEV41_18635	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GEV41_18645	COG4774	siderophore transport
GEV41_18660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV41_18665	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GEV41_18690	COG1192	Involved in chromosome partitioning
GEV41_18695	COG0477	Major facilitator Superfamily
GEV41_18715	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GEV41_18720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GEV41_18735	COG0745	RESPONSE REGULATOR receiver
GEV41_18750	COG2259	Doxx family
GEV41_18760	COG3220	belongs to the UPF0276 family
GEV41_18785	COG0417	DNA replication proofreading
GEV41_18790	COG2814	Major facilitator Superfamily
GEV41_18795	COG0583	DNA-binding transcription factor activity
GEV41_18800	COG0583	DNA-binding transcription factor activity
GEV41_18850	COG1999	signal sequence binding
GEV41_18855	COG0316	Belongs to the HesB IscA family
GEV41_18855	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GEV41_18860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GEV41_18915	COG2814	Major facilitator Superfamily
GEV41_18920	COG2223	nitrite transmembrane transporter activity
GEV41_18925	COG2207	Transcriptional regulator
GEV41_18930	COG2866	Carboxypeptidase
GEV41_18970	COG4251	negative regulation of phosphorylation
GEV41_18975	COG0745	RESPONSE REGULATOR receiver
GEV41_18995	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GEV41_19035	COG0745	RESPONSE REGULATOR receiver
GEV41_19055	COG0720	synthase
GEV41_19070	COG2079	MmgE PrpD family protein
GEV41_19085	COG0372	Belongs to the citrate synthase family
GEV41_19095	COG1802	Transcriptional regulator
GEV41_19100	COG0189	ligase activity
GEV41_19100	COG4067	protein conserved in archaea
GEV41_19135	COG0589	response to stress
GEV41_19140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GEV41_19145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GEV41_19160	COG1376	ErfK ybiS ycfS ynhG family protein
GEV41_19160	COG1388	LysM domain
GEV41_19175	COG4181	ATPase activity
GEV41_19180	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GEV41_19185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GEV41_19195	COG2259	Doxx family
GEV41_19200	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GEV41_19240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GEV41_19250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GEV41_19255	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GEV41_19260	COG0740	serine-type endopeptidase activity
GEV41_19265	COG0544	peptidyl-prolyl cis-trans isomerase activity
GEV41_19295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GEV41_19310	COG0395	ABC-type sugar transport system, permease component
GEV41_19320	COG3842	ATPase activity
GEV41_19325	COG3842	ATPase activity
GEV41_19330	COG3284	Transcriptional regulator
GEV41_19340	COG0840	transmembrane signaling receptor activity
GEV41_19355	COG2186	Transcriptional regulator
GEV41_19375	COG0583	DNA-binding transcription factor activity
GEV41_19380	COG0840	transmembrane signaling receptor activity
GEV41_19385	COG3949	Membrane
GEV41_19390	COG0251	oxidation-reduction process
GEV41_19405	COG0730	response to heat
GEV41_19455	COG5006	permease, DMT superfamily
GEV41_19490	COG1335	isochorismatase
GEV41_19505	COG2111	Na H antiporter
GEV41_19505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GEV41_19510	COG1006	Multisubunit Na H antiporter MnhC subunit
GEV41_19515	COG0651	ATP synthesis coupled electron transport
GEV41_19525	COG2212	antiporter activity
GEV41_19530	COG1320	monovalent cation:proton antiporter activity
GEV41_19555	COG1024	Enoyl-CoA hydratase
GEV41_19560	COG1960	acyl-CoA dehydrogenase activity
GEV41_19565	COG0183	Belongs to the thiolase family
GEV41_19575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GEV41_19590	COG2207	Transcriptional regulator
GEV41_19595	COG0583	DNA-binding transcription factor activity
GEV41_19600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GEV41_19605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GEV41_19645	COG1238	metal cluster binding
GEV41_19650	COG0596	Alpha beta hydrolase
GEV41_19660	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GEV41_19665	COG2133	pyrroloquinoline quinone binding
GEV41_19675	COG0010	Belongs to the arginase family
GEV41_19705	COG1595	DNA-templated transcription, initiation
GEV41_19730	COG0589	response to stress
GEV41_19740	COG3383	formate dehydrogenase (NAD+) activity
GEV41_19770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GEV41_19775	COG0174	glutamine synthetase
GEV41_19785	COG0583	DNA-binding transcription factor activity
GEV41_19790	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_19805	COG1301	dicarboxylic acid transport
GEV41_19815	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GEV41_19820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GEV41_19865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GEV41_19870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GEV41_19885	COG4566	intracellular signal transduction
GEV41_19895	COG2853	Lipoprotein
GEV41_19910	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GEV41_19910	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GEV41_19930	COG4591	ABC-type transport system involved in lipoprotein release permease component
GEV41_19935	COG1136	(ABC) transporter
GEV41_19940	COG4591	ABC-type transport system involved in lipoprotein release permease component
GEV41_19950	COG0584	glycerophosphoryl diester phosphodiesterase
GEV41_19955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GEV41_19960	COG1477	protein flavinylation
GEV41_19970	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GEV41_19980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GEV41_19995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GEV41_20025	COG0183	Belongs to the thiolase family
GEV41_20030	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV41_20030	COG1024	Enoyl-CoA hydratase
GEV41_20040	COG0589	response to stress
GEV41_20050	COG0741	lytic transglycosylase activity
GEV41_20065	COG0835	chemotaxis
GEV41_20065	COG0784	Response regulator, receiver
GEV41_20075	COG3851	Histidine kinase
GEV41_20080	COG2197	response regulator
GEV41_20085	COG1597	lipid kinase activity
GEV41_20090	COG0438	transferase activity, transferring glycosyl groups
GEV41_20100	COG0521	Mo-molybdopterin cofactor biosynthetic process
GEV41_20120	COG1132	(ABC) transporter
GEV41_20125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GEV41_20130	COG0425	Belongs to the sulfur carrier protein TusA family
GEV41_20145	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GEV41_20155	COG0840	transmembrane signaling receptor activity
GEV41_20180	COG0004	ammonium transporteR
GEV41_20235	COG2197	response regulator
GEV41_20240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV41_20240	COG2205	protein histidine kinase activity
GEV41_20245	COG3171	Protein conserved in bacteria
GEV41_20250	COG2027	D-alanyl-D-alanine carboxypeptidase
GEV41_20260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GEV41_20260	COG0116	Belongs to the methyltransferase superfamily
GEV41_20265	COG3130	regulation of translation
GEV41_20270	COG0167	dihydroorotate dehydrogenase activity
GEV41_20275	COG1116	anion transmembrane transporter activity
GEV41_20275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GEV41_20280	COG3707	response regulator
GEV41_20285	COG2223	nitrite transmembrane transporter activity
GEV41_20310	COG0668	transmembrane transport
GEV41_20325	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GEV41_20345	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GEV41_20365	COG0583	DNA-binding transcription factor activity
GEV41_20370	COG0019	diaminopimelate decarboxylase activity
GEV41_20410	COG1538	Outer membrane efflux protein
GEV41_20430	COG2188	Transcriptional regulator
GEV41_20435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GEV41_20445	COG0789	Transcriptional regulator
GEV41_20450	COG3237	CsbD-like
GEV41_20460	COG2851	Citrate transporter
GEV41_20465	COG1301	dicarboxylic acid transport
GEV41_20470	COG2828	Protein conserved in bacteria
GEV41_20475	COG0583	DNA-binding transcription factor activity
GEV41_20485	COG0246	Mannitol dehydrogenase
GEV41_20500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEV41_20505	COG3135	benzoate transporter
GEV41_20520	COG0714	Associated with various cellular activities
GEV41_20555	COG0420	3'-5' exonuclease activity
GEV41_20570	COG2706	6-phosphogluconolactonase activity
GEV41_20590	COG0308	aminopeptidase N
GEV41_20600	COG3139	Protein of unknown function (DUF1315)
GEV41_20605	COG0705	Rhomboid family
GEV41_20610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GEV41_20615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GEV41_20625	COG3038	cytochrome b561
GEV41_20640	COG1902	pentaerythritol trinitrate reductase activity
GEV41_20640	COG0446	pyridine nucleotide-disulphide oxidoreductase
GEV41_20685	COG1063	alcohol dehydrogenase
GEV41_20725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GEV41_20730	COG2814	Major facilitator Superfamily
GEV41_20740	COG2814	Major facilitator Superfamily
GEV41_20795	COG1063	alcohol dehydrogenase
GEV41_20905	COG1286	toxin biosynthetic process
GEV41_20915	COG0285	dihydrofolate synthase activity
GEV41_20920	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GEV41_20925	COG0135	phosphoribosylanthranilate isomerase activity
GEV41_20960	COG0473	3-isopropylmalate dehydrogenase activity
GEV41_20965	COG2226	methyltransferase
GEV41_20970	COG0066	3-isopropylmalate dehydratase activity
GEV41_20975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GEV41_21005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GEV41_21015	COG0596	Alpha beta hydrolase
GEV41_21055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GEV41_21070	COG0556	nucleotide-excision repair
GEV41_21130	COG0084	hydrolase, TatD family'
GEV41_21140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GEV41_21145	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GEV41_21155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GEV41_21160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV41_21175	COG0416	fatty acid biosynthetic process
GEV41_21180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GEV41_21190	COG0424	maF-like protein
GEV41_21195	COG0616	signal peptide processing
GEV41_21195	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GEV41_21200	COG0546	phosphoglycolate phosphatase activity
GEV41_21215	COG1530	ribonuclease E activity
GEV41_21220	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GEV41_21225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GEV41_21230	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GEV41_21235	COG2835	tetraacyldisaccharide 4'-kinase activity
GEV41_21240	COG1663	tetraacyldisaccharide 4'-kinase activity
GEV41_21245	COG0848	biopolymer transport protein
GEV41_21250	COG0811	peptide transport
GEV41_21265	COG0842	Transport permease protein
GEV41_21270	COG1131	(ABC) transporter
GEV41_21275	COG0625	glutathione transferase activity
GEV41_21300	COG3121	Chaperone
GEV41_21350	COG3188	usher protein
GEV41_21405	COG1956	GAF domain-containing protein
GEV41_21415	COG2205	protein histidine kinase activity
GEV41_21415	COG5002	protein histidine kinase activity
GEV41_21415	COG0784	Response regulator, receiver
GEV41_21420	COG0386	Belongs to the glutathione peroxidase family
GEV41_21425	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GEV41_21430	COG0436	Aminotransferase
GEV41_21445	COG0501	Belongs to the peptidase M48B family
GEV41_21450	COG0500	methyltransferase
GEV41_21455	COG3384	dioxygenase
GEV41_21470	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GEV41_21490	COG0583	DNA-binding transcription factor activity
GEV41_21500	COG0583	DNA-binding transcription factor activity
GEV41_21505	COG1846	Transcriptional regulator
GEV41_21510	COG1764	response to oxidative stress
GEV41_21515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GEV41_21535	COG0583	DNA-binding transcription factor activity
GEV41_21540	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_21545	COG0583	DNA-binding transcription factor activity
GEV41_21550	COG2814	Major facilitator Superfamily
GEV41_21565	COG4773	Receptor
GEV41_21585	COG0598	Magnesium transport protein CorA
GEV41_21590	COG0519	Catalyzes the synthesis of GMP from XMP
GEV41_21610	COG1368	sulfuric ester hydrolase activity
GEV41_21650	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GEV41_21655	COG2814	Major facilitator Superfamily
GEV41_21660	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GEV41_21695	COG2840	Smr protein MutS2
GEV41_21700	COG0302	gtp cyclohydrolase
GEV41_21710	COG0625	glutathione transferase activity
GEV41_21715	COG3135	benzoate transporter
GEV41_21720	COG0840	transmembrane signaling receptor activity
GEV41_21735	COG2130	NADP-dependent
GEV41_21745	COG0284	orotidine-5'-phosphate decarboxylase activity
GEV41_21755	COG1555	photosystem II stabilization
GEV41_21760	COG3328	transposase activity
GEV41_21790	COG0166	Belongs to the GPI family
GEV41_21795	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GEV41_21800	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GEV41_21800	COG0517	IMP dehydrogenase activity
GEV41_21810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GEV41_21825	COG0438	transferase activity, transferring glycosyl groups
GEV41_21835	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GEV41_21845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GEV41_21870	COG0438	transferase activity, transferring glycosyl groups
GEV41_21870	COG1216	Glycosyl transferase, family 2
GEV41_21875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GEV41_21880	COG1083	cytidylyl-transferase
GEV41_21940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GEV41_21955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GEV41_21965	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GEV41_21975	COG0776	regulation of translation
GEV41_21990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GEV41_21995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GEV41_22005	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GEV41_22015	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GEV41_22020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GEV41_22025	COG0546	phosphoglycolate phosphatase activity
GEV41_22030	COG1028	Short-chain dehydrogenase reductase Sdr
GEV41_22040	COG5001	Diguanylate cyclase
GEV41_22040	COG5002	protein histidine kinase activity
GEV41_22060	COG0271	Belongs to the BolA IbaG family
GEV41_22070	COG0114	fumarate hydratase activity
GEV41_22075	COG0697	spore germination
GEV41_22080	COG2326	polyphosphate kinase activity
GEV41_22085	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GEV41_22085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_22090	COG0367	asparagine synthase
GEV41_22095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GEV41_22095	COG0189	ligase activity
GEV41_22100	COG1363	Peptidase, m42
GEV41_22105	COG3089	Belongs to the UPF0270 family
GEV41_22140	COG3436	PFAM IS66 Orf2 family protein
GEV41_22160	COG2205	protein histidine kinase activity
GEV41_22160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV41_22165	COG2197	response regulator
GEV41_22190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GEV41_22195	COG3162	membrane
GEV41_22200	COG2113	Glycine betaine
GEV41_22220	COG2853	Lipoprotein
GEV41_22230	COG1560	Kdo2-lipid A biosynthetic process
GEV41_22235	COG0850	regulation of cytokinetic process
GEV41_22240	COG2894	cell division
GEV41_22245	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GEV41_22250	COG0564	pseudouridine synthase activity
GEV41_22255	COG1362	aminopeptidase activity
GEV41_22260	COG0668	transmembrane transport
GEV41_22280	COG1176	ABC-type spermidine putrescine transport system, permease component I
GEV41_22310	COG5001	Diguanylate cyclase
GEV41_22310	COG3300	MHYT domain
GEV41_22335	COG3339	Conserved Protein
GEV41_22340	COG0545	Peptidyl-prolyl cis-trans isomerase
GEV41_22345	COG0583	DNA-binding transcription factor activity
GEV41_22365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GEV41_22365	COG2146	nitrite reductase [NAD(P)H] activity
GEV41_22370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GEV41_22370	COG2146	nitrite reductase [NAD(P)H] activity
GEV41_22375	COG0243	molybdopterin cofactor binding
GEV41_22385	COG0024	Methionine aminopeptidase
GEV41_22410	COG2974	May be involved in recombination
GEV41_22420	COG0477	Major facilitator Superfamily
GEV41_22430	COG2814	Major facilitator Superfamily
GEV41_22435	COG2188	Transcriptional regulator
GEV41_22440	COG2814	Major facilitator Superfamily
GEV41_22445	COG2205	protein histidine kinase activity
GEV41_22480	COG0583	DNA-binding transcription factor activity
GEV41_22500	COG1846	Transcriptional regulator
GEV41_22510	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GEV41_22515	COG0406	alpha-ribazole phosphatase activity
GEV41_22520	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GEV41_22530	COG1492	cobalamin metabolic process
GEV41_22545	COG0778	Nitroreductase
GEV41_22550	COG1797	cobyrinic acid a,c-diamide synthase activity
GEV41_22560	COG0791	NLP P60 protein
GEV41_22565	COG0791	NLP P60 protein
GEV41_22575	COG0628	permease
GEV41_22590	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GEV41_22595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GEV41_22625	COG3122	Protein conserved in bacteria
GEV41_22630	COG3956	TIGRFAM MazG family protein
GEV41_22635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GEV41_22640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GEV41_22660	COG0784	Response regulator, receiver
GEV41_22660	COG5002	protein histidine kinase activity
GEV41_22660	COG2205	protein histidine kinase activity
GEV41_22665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEV41_22710	COG0037	tRNA processing
GEV41_22720	COG3091	SprT-like family
GEV41_22730	COG0583	DNA-binding transcription factor activity
GEV41_22770	COG2137	regulation of response to DNA damage stimulus
GEV41_22775	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GEV41_22780	COG1546	Belongs to the CinA family
GEV41_22790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GEV41_22795	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GEV41_22815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GEV41_22820	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GEV41_22825	COG0585	pseudouridine synthase activity
GEV41_22830	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GEV41_22840	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GEV41_22850	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GEV41_22860	COG0148	phosphopyruvate hydratase activity
GEV41_22865	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GEV41_22870	COG0504	CTP synthase activity
GEV41_22875	COG0037	tRNA processing
GEV41_22880	COG0825	malonyl-CoA metabolic process
GEV41_22890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GEV41_22895	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GEV41_22900	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GEV41_22905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GEV41_22910	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GEV41_22930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GEV41_22940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GEV41_22945	COG0233	cytoplasmic translational termination
GEV41_22950	COG0528	UMP kinase activity
GEV41_22955	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GEV41_22960	COG0052	Belongs to the universal ribosomal protein uS2 family
GEV41_22965	COG0024	Methionine aminopeptidase
GEV41_22970	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GEV41_22975	COG0436	Aminotransferase
GEV41_22985	COG0025	NhaP-type Na H and K H
GEV41_23010	COG1393	Belongs to the ArsC family
GEV41_23015	COG2171	N-acyltransferase activity
GEV41_23020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GEV41_23030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GEV41_23035	COG1215	transferase activity, transferring glycosyl groups
GEV41_23040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GEV41_23045	COG2226	methyltransferase
GEV41_23060	COG2937	Belongs to the GPAT DAPAT family
GEV41_23080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GEV41_23095	COG0742	ribosomal rna small subunit methyltransferase
GEV41_23130	COG0563	adenylate kinase activity
GEV41_23135	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GEV41_23155	COG2885	chlorophyll binding
GEV41_23165	COG1073	alpha beta
GEV41_23190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GEV41_23200	COG5001	Diguanylate cyclase
GEV41_23200	COG4251	negative regulation of phosphorylation
GEV41_23200	COG3706	GGDEF domain
GEV41_23200	COG2203	Gaf domain
GEV41_23205	COG2201	protein-glutamate methylesterase activity
GEV41_23220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GEV41_23220	COG0457	Tetratricopeptide repeat
GEV41_23230	COG0840	transmembrane signaling receptor activity
GEV41_23235	COG2979	Protein of unknown function (DUF533)
GEV41_23240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GEV41_23245	COG3842	ATPase activity
GEV41_23250	COG1176	ABC-type spermidine putrescine transport system, permease component I
GEV41_23255	COG1177	transmembrane transport
GEV41_23260	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_23275	COG1902	pentaerythritol trinitrate reductase activity
GEV41_23315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV41_23350	COG4974	Belongs to the 'phage' integrase family
GEV41_23360	COG1607	acyl-coa hydrolase
GEV41_23365	COG0335	large ribosomal subunit rRNA binding
GEV41_23370	COG0336	Belongs to the RNA methyltransferase TrmD family
GEV41_23375	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GEV41_23380	COG0228	four-way junction DNA binding
GEV41_23385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GEV41_23395	COG4536	flavin adenine dinucleotide binding
GEV41_23400	COG0477	Major facilitator Superfamily
GEV41_23405	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GEV41_23425	COG0494	nUDIX hydrolase
GEV41_23455	COG4628	conserved protein (DUF2132)
GEV41_23460	COG4206	TonB-dependent receptor
GEV41_23480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GEV41_23490	COG2226	methyltransferase
GEV41_23495	COG0500	methyltransferase
GEV41_23515	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GEV41_23520	COG1381	Involved in DNA repair and RecF pathway recombination
GEV41_23525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GEV41_23530	COG0571	ribonuclease III activity
GEV41_23535	COG0681	Belongs to the peptidase S26 family
GEV41_23540	COG0481	GTPase activity
GEV41_23545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GEV41_23575	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GEV41_23580	COG0354	folic acid binding
GEV41_23620	COG3180	Ammonia monooxygenase
GEV41_23630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GEV41_23660	COG2267	carboxylic ester hydrolase activity
GEV41_23750	COG0583	DNA-binding transcription factor activity
GEV41_23775	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GEV41_23780	COG2433	Pfam Transposase IS66
GEV41_23855	COG4977	sequence-specific DNA binding
GEV41_23860	COG3949	Membrane
GEV41_23920	COG4191	Histidine kinase
GEV41_23930	COG0477	Major facilitator Superfamily
GEV41_23960	COG2207	Transcriptional regulator
GEV41_23970	COG0583	DNA-binding transcription factor activity
GEV41_23975	COG2910	NAD(P)H-binding
GEV41_23985	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GEV41_23990	COG0477	Major facilitator Superfamily
GEV41_23995	COG1309	transcriptional regulator
GEV41_24000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GEV41_24030	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GEV41_24035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GEV41_24040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GEV41_24045	COG0477	Major facilitator Superfamily
GEV41_24050	COG0183	Belongs to the thiolase family
GEV41_24055	COG2814	Major facilitator Superfamily
GEV41_24060	COG1414	Transcriptional regulator
GEV41_24075	COG0306	phosphate transporter
GEV41_24080	COG0433	COG0433 Predicted ATPase
GEV41_24085	COG0840	transmembrane signaling receptor activity
GEV41_24090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GEV41_24090	COG0438	transferase activity, transferring glycosyl groups
GEV41_24110	COG0788	formyltetrahydrofolate deformylase activity
GEV41_24120	COG2925	Exonuclease
GEV41_24140	COG0459	protein refolding
GEV41_24145	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GEV41_24150	COG3030	protein affecting phage T7 exclusion by the F plasmid
GEV41_24185	COG0668	transmembrane transport
GEV41_24190	COG1666	GTP binding
GEV41_24205	COG2096	Adenosyltransferase
GEV41_24210	COG0494	nUDIX hydrolase
GEV41_24220	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GEV41_24225	COG0653	protein targeting
GEV41_24240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GEV41_24245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GEV41_24260	COG1181	Belongs to the D-alanine--D-alanine ligase family
GEV41_24265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GEV41_24270	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GEV41_24275	COG0772	Belongs to the SEDS family
GEV41_24280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GEV41_24285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GEV41_24290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GEV41_24295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GEV41_24310	COG0275	rRNA processing
GEV41_24315	COG2001	Belongs to the MraZ family
GEV41_24330	COG3107	peptidoglycan biosynthetic process
GEV41_24335	COG0792	nuclease activity
GEV41_24340	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GEV41_24345	COG2823	Periplasmic or secreted lipoprotein
GEV41_24350	COG2969	positive regulation of protein catabolic process
GEV41_24355	COG0625	glutathione transferase activity
GEV41_24360	COG2857	Cytochrome c1
GEV41_24365	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GEV41_24370	COG0723	plastoquinol--plastocyanin reductase activity
GEV41_24375	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GEV41_24380	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GEV41_24385	COG0667	Aldo Keto reductase
GEV41_24395	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GEV41_24400	COG0180	Tryptophanyl-tRNA synthetase
GEV41_24420	COG1522	sequence-specific DNA binding
GEV41_24430	COG0175	sulfate reduction
GEV41_24445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GEV41_24450	COG1126	abc transporter atp-binding protein
GEV41_24455	COG0765	amino acid transport
GEV41_24460	COG4597	amino acid ABC transporter
GEV41_24465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV41_24470	COG0400	carboxylic ester hydrolase activity
GEV41_24475	COG0513	Belongs to the DEAD box helicase family
GEV41_24490	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GEV41_24495	COG0315	cyclic pyranopterin monophosphate synthase activity
GEV41_24500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GEV41_24510	COG3022	response to hydroperoxide
GEV41_24515	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GEV41_24520	COG1215	transferase activity, transferring glycosyl groups
GEV41_24525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GEV41_24530	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GEV41_24540	COG3420	alginic acid biosynthetic process
GEV41_24555	COG1696	Membrane protein involved in D-alanine export
GEV41_24570	COG0662	Cupin 2, conserved barrel domain protein
GEV41_24570	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GEV41_24585	COG0300	oxidoreductase activity
GEV41_24620	COG1566	PFAM secretion protein HlyD family protein
GEV41_24640	COG0583	DNA-binding transcription factor activity
GEV41_24645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEV41_24650	COG0697	spore germination
GEV41_24655	COG2207	Transcriptional regulator
GEV41_24655	COG3708	Transcriptional regulator
GEV41_24740	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GEV41_24760	COG1346	cytolysis
GEV41_24770	COG0583	DNA-binding transcription factor activity
GEV41_24780	COG1366	Belongs to the anti-sigma-factor antagonist family
GEV41_24825	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GEV41_24835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GEV41_24845	COG0523	cobalamin synthesis protein
GEV41_24850	COG2879	small protein
GEV41_24855	COG1966	Carbon starvation protein
GEV41_24865	COG2233	PERMEase
GEV41_24875	COG1970	mechanosensitive ion channel activity
GEV41_24890	COG2197	response regulator
GEV41_24895	COG2813	Specifically methylates the guanine in position
GEV41_24905	COG1294	oxidase, subunit
GEV41_24910	COG1271	oxidase subunit
GEV41_24920	COG2252	PERMEase
GEV41_24925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GEV41_24930	COG3485	protocatechuate 3,4-dioxygenase
GEV41_24935	COG3485	protocatechuate 3,4-dioxygenase
GEV41_24940	COG2321	neutral zinc metallopeptidase
GEV41_24945	COG0840	transmembrane signaling receptor activity
GEV41_24955	COG0583	DNA-binding transcription factor activity
GEV41_24960	COG2249	NAD(P)H dehydrogenase (quinone) activity
GEV41_25010	COG2885	chlorophyll binding
GEV41_25010	COG3047	cAMP biosynthetic process
GEV41_25015	COG2199	diguanylate cyclase activity
GEV41_25025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GEV41_25030	COG1074	ATP-dependent DNA helicase activity
GEV41_25035	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GEV41_25080	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GEV41_25085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GEV41_25090	COG1183	phosphatidylcholine synthase activity
GEV41_25095	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GEV41_25105	COG0028	Belongs to the TPP enzyme family
GEV41_25110	COG3098	single-species biofilm formation
GEV41_25120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GEV41_25140	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GEV41_25145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV41_25150	COG4558	Periplasmic binding protein
GEV41_25160	COG1489	DNA binding
GEV41_25175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GEV41_25185	COG4191	Histidine kinase
GEV41_25210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GEV41_25215	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GEV41_25220	COG0166	Belongs to the GPI family
GEV41_25230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GEV41_25255	COG2823	Periplasmic or secreted lipoprotein
GEV41_25260	COG1185	polyribonucleotide nucleotidyltransferase activity
GEV41_25270	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GEV41_25275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GEV41_25280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GEV41_25285	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GEV41_25290	COG0195	Participates in both transcription termination and antitermination
GEV41_25295	COG0779	Required for maturation of 30S ribosomal subunits
GEV41_25310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GEV41_25315	COG0149	triose-phosphate isomerase activity
GEV41_25320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GEV41_25325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GEV41_25335	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GEV41_25350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GEV41_25355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GEV41_25360	COG0505	Belongs to the CarA family
GEV41_25365	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GEV41_25370	COG0484	heat shock protein binding
GEV41_25375	COG0443	Heat shock 70 kDa protein
GEV41_25380	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GEV41_25385	COG0497	DNA recombination
GEV41_25390	COG0735	belongs to the Fur family
GEV41_25395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GEV41_25405	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GEV41_25410	COG2186	Transcriptional regulator
GEV41_25415	COG1620	l-lactate permease
GEV41_25420	COG1304	FMN binding
GEV41_25470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GEV41_25485	COG1401	restriction endodeoxyribonuclease activity
GEV41_25485	COG1401	restriction endodeoxyribonuclease activity
GEV41_25525	COG4774	siderophore transport
GEV41_25570	COG1064	alcohol dehydrogenase
GEV41_25580	COG0546	phosphoglycolate phosphatase activity
GEV41_25585	COG1946	Acyl-CoA thioesterase
GEV41_25595	COG0406	alpha-ribazole phosphatase activity
GEV41_25605	COG0784	Response regulator, receiver
GEV41_25605	COG2205	protein histidine kinase activity
GEV41_25615	COG0784	Response regulator, receiver
GEV41_25615	COG2205	protein histidine kinase activity
GEV41_25620	COG2197	response regulator
GEV41_25630	COG3121	Chaperone
GEV41_25645	COG3416	Protein conserved in bacteria
GEV41_25665	COG0123	including yeast histone deacetylase and acetoin utilization protein
GEV41_25680	COG0513	Belongs to the DEAD box helicase family
GEV41_25685	COG0697	spore germination
GEV41_25690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GEV41_25700	COG3416	Protein conserved in bacteria
GEV41_25715	COG1643	Atp-dependent helicase
GEV41_25735	COG1522	sequence-specific DNA binding
GEV41_25750	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GEV41_25755	COG1960	acyl-CoA dehydrogenase activity
GEV41_25760	COG3850	Histidine kinase
GEV41_25760	COG4999	Histidine kinase
GEV41_25760	COG2205	protein histidine kinase activity
GEV41_25760	COG3437	response regulator, receiver
GEV41_25765	COG0351	phosphomethylpyrimidine kinase
GEV41_25770	COG0352	thiamine-phosphate diphosphorylase activity
GEV41_25775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GEV41_25790	COG1702	phosphate starvation-inducible protein PhoH
GEV41_25795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GEV41_25800	COG4535	Mg2 and Co2 transporter CorC
GEV41_25805	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GEV41_25825	COG0495	leucyl-tRNA aminoacylation
GEV41_25850	COG2951	lytic endotransglycosylase activity
GEV41_25855	COG1619	proteins homologs of microcin C7 resistance protein MccF
GEV41_25860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GEV41_25865	COG0321	lipoyl(octanoyl) transferase activity
GEV41_25870	COG2921	Belongs to the UPF0250 family
GEV41_25875	COG1686	Belongs to the peptidase S11 family
GEV41_25885	COG2951	lytic endotransglycosylase activity
GEV41_25890	COG0772	Belongs to the SEDS family
GEV41_25895	COG0768	penicillin binding
GEV41_25900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GEV41_25910	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GEV41_25915	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GEV41_25925	COG2094	Belongs to the DNA glycosylase MPG family
GEV41_25930	COG0586	Pfam SNARE associated Golgi protein
GEV41_25940	COG1346	cytolysis
GEV41_25955	COG2264	protein methyltransferase activity
GEV41_25965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GEV41_25975	COG0138	bifunctional purine biosynthesis protein purh
GEV41_25985	COG0151	Belongs to the GarS family
GEV41_25995	COG2095	MarC family integral membrane protein
GEV41_26030	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GEV41_26040	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GEV41_26055	COG0330	HflC and HflK could
GEV41_26075	COG4774	siderophore transport
GEV41_26085	COG1113	amino acid transport
GEV41_26110	COG0411	ABC transporter
GEV41_26125	COG0789	Transcriptional regulator
GEV41_26130	COG0484	heat shock protein binding
GEV41_26135	COG0443	Heat shock 70 kDa protein
GEV41_26160	COG0697	spore germination
GEV41_26165	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GEV41_26180	COG2982	Protein involved in outer membrane biogenesis
GEV41_26210	COG4221	oxidoreductase activity
GEV41_26240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GEV41_26245	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GEV41_26260	COG1032	radical SAM domain protein
GEV41_26280	COG5265	(ABC) transporter
GEV41_26285	COG0305	Participates in initiation and elongation during chromosome replication
GEV41_26290	COG0359	binds to the 23S rRNA
GEV41_26300	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GEV41_26305	COG0360	Binds together with S18 to 16S ribosomal RNA
GEV41_26310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GEV41_26330	COG1840	ABC-type Fe3 transport system, periplasmic component
GEV41_26335	COG1178	ABC-type Fe3 transport system permease component
GEV41_26355	COG0840	transmembrane signaling receptor activity
GEV41_26360	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GEV41_26365	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GEV41_26370	COG0330	HflC and HflK could
GEV41_26375	COG0330	HflC and HflK could
GEV41_26380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GEV41_26385	COG1923	regulation of RNA biosynthetic process
GEV41_26390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GEV41_26395	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GEV41_26400	COG0860	N-Acetylmuramoyl-L-alanine amidase
GEV41_26405	COG0802	atpase or kinase
GEV41_26410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GEV41_26410	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GEV41_26425	COG2860	membrane
GEV41_26430	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GEV41_26435	COG1162	GTPase activity
GEV41_26445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GEV41_26460	COG0688	phosphatidylethanolamine metabolic process
GEV41_26465	COG3830	Belongs to the UPF0237 family
GEV41_26465	COG0560	Phosphoserine phosphatase
GEV41_26490	COG3577	Aspartyl protease
GEV41_26505	COG3150	esterase
GEV41_26510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GEV41_26520	COG0494	nUDIX hydrolase
GEV41_26535	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GEV41_26540	COG1538	Outer membrane efflux protein
GEV41_26545	COG1519	Transferase
GEV41_26550	COG0583	DNA-binding transcription factor activity
GEV41_26565	COG0667	Aldo Keto reductase
GEV41_26575	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GEV41_26575	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GEV41_26580	COG1132	(ABC) transporter
GEV41_26595	COG0438	transferase activity, transferring glycosyl groups
GEV41_26620	COG0438	transferase activity, transferring glycosyl groups
GEV41_26625	COG2192	nodulation
GEV41_26630	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GEV41_26635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GEV41_26640	COG0506	proline dehydrogenase activity
GEV41_26640	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GEV41_26640	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GEV41_26655	COG1960	acyl-CoA dehydrogenase activity
GEV41_26665	COG0312	modulator of DNA gyrase
GEV41_26670	COG0477	Major facilitator Superfamily
GEV41_26675	COG0513	Belongs to the DEAD box helicase family
GEV41_26680	COG2081	HI0933 family
GEV41_26685	COG1289	transmembrane transporter activity
GEV41_26690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV41_26695	COG2153	protein acetylation
GEV41_26705	COG1451	nucleotide metabolic process
GEV41_26730	COG0126	phosphoglycerate kinase activity
GEV41_26735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GEV41_26740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GEV41_26745	COG0640	Transcriptional regulator
GEV41_26750	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GEV41_26760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GEV41_26800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GEV41_26805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GEV41_26825	COG0513	Belongs to the DEAD box helicase family
GEV41_26830	COG2353	YceI-like domain
GEV41_26835	COG3038	cytochrome b561
GEV41_26855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GEV41_26860	COG1272	protein, Hemolysin III
GEV41_26870	COG0643	Histidine kinase
GEV41_26870	COG2198	Histidine kinase
GEV41_26870	COG0784	Response regulator, receiver
GEV41_26895	COG0189	ligase activity
GEV41_26905	COG1678	Uncharacterized ACR, COG1678
GEV41_26910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GEV41_26915	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GEV41_26920	COG0540	Belongs to the ATCase OTCase family
GEV41_26925	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GEV41_26930	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GEV41_26935	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GEV41_26985	COG2226	methyltransferase
GEV41_26995	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GEV41_27000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GEV41_27005	COG0140	phosphoribosyl-ATP diphosphatase activity
GEV41_27010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GEV41_27030	COG0840	transmembrane signaling receptor activity
GEV41_27040	COG0840	transmembrane signaling receptor activity
GEV41_27045	COG1126	abc transporter atp-binding protein
GEV41_27050	COG0765	amino acid transport
GEV41_27060	COG2943	transferase activity, transferring hexosyl groups
GEV41_27065	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GEV41_27070	COG1490	D-aminoacyl-tRNA deacylase activity
GEV41_27085	COG1228	amidohydrolase
GEV41_27095	COG2986	histidine ammonia-lyase
GEV41_27100	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GEV41_27120	COG2188	Transcriptional regulator
GEV41_27125	COG0402	S-adenosylhomocysteine deaminase activity
GEV41_27145	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GEV41_27150	COG0058	SHG alpha-glucan phosphorylase activity
GEV41_27165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GEV41_27165	COG0301	tRNA thio-modification
GEV41_27175	COG3852	Histidine kinase
GEV41_27190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GEV41_27195	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GEV41_27205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GEV41_27210	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GEV41_27215	COG4942	peptidase
GEV41_27220	COG0793	Belongs to the peptidase S41A family
GEV41_27225	COG2861	carbohydrate metabolic process
GEV41_27235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GEV41_27240	COG1309	transcriptional regulator
GEV41_27245	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_27250	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GEV41_27260	COG3263	regulation of cellular component size
GEV41_27265	COG1196	nuclear chromosome segregation
GEV41_27265	COG3264	Mechanosensitive ion channel
GEV41_27270	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GEV41_27275	COG3118	belongs to the thioredoxin family
GEV41_27280	COG1192	Involved in chromosome partitioning
GEV41_27285	COG0583	DNA-binding transcription factor activity
GEV41_27290	COG2814	Major facilitator Superfamily
GEV41_27300	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GEV41_27305	COG0493	'glutamate synthase
GEV41_27310	COG0070	glutamate synthase
GEV41_27310	COG0069	glutamate synthase activity
GEV41_27310	COG0067	glutamate synthase
GEV41_27320	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GEV41_27325	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GEV41_27355	COG0281	malic enzyme
GEV41_27365	COG0254	rRNA binding
GEV41_27370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GEV41_27375	COG0018	arginyl-trna synthetase
GEV41_27390	COG0791	NLP P60 protein
GEV41_27415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GEV41_27420	COG2813	Specifically methylates the guanine in position
GEV41_27420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GEV41_27430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GEV41_27435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GEV41_27445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GEV41_27450	COG2022	thiamine diphosphate biosynthetic process
GEV41_27460	COG2363	Small membrane protein
GEV41_27465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GEV41_27475	COG2177	Part of the ABC transporter FtsEX involved in
GEV41_27480	COG2884	Cell division ATP-binding protein ftsE
GEV41_27485	COG0552	protein localization to endoplasmic reticulum
GEV41_27495	COG0612	Peptidase, M16
GEV41_27500	COG0612	Peptidase, M16
GEV41_27505	COG0742	ribosomal rna small subunit methyltransferase
GEV41_27535	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GEV41_27540	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GEV41_27545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GEV41_27555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GEV41_27565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GEV41_27570	COG0129	dihydroxy-acid dehydratase activity
GEV41_27605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GEV41_27610	COG1840	ABC-type Fe3 transport system, periplasmic component
GEV41_27615	COG1178	ABC-type Fe3 transport system permease component
GEV41_27620	COG3842	ATPase activity
GEV41_27630	COG0583	DNA-binding transcription factor activity
GEV41_27640	COG0789	Transcriptional regulator
GEV41_27645	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GEV41_27650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GEV41_27655	COG0730	response to heat
GEV41_27665	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GEV41_27670	COG0494	nUDIX hydrolase
GEV41_27685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GEV41_27690	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GEV41_27695	COG3204	pilus organization
GEV41_27705	COG0179	Fumarylacetoacetate (FAA) hydrolase
GEV41_27710	COG0277	FAD linked oxidase domain protein
GEV41_27715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GEV41_27775	COG3829	transcription factor binding
GEV41_27785	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GEV41_27790	COG4208	sulfate ABC transporter
GEV41_27805	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GEV41_27815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GEV41_27840	COG1177	transmembrane transport
GEV41_27845	COG1176	ABC-type spermidine putrescine transport system, permease component I
GEV41_27850	COG3842	ATPase activity
GEV41_27870	COG0174	glutamine synthetase
GEV41_27880	COG0174	glutamine synthetase
GEV41_27885	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GEV41_27885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GEV41_27890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GEV41_27900	COG1522	sequence-specific DNA binding
GEV41_27920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GEV41_27920	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GEV41_27925	COG0509	glycine decarboxylation via glycine cleavage system
GEV41_27930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GEV41_27935	COG1178	ABC-type Fe3 transport system permease component
GEV41_27945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GEV41_27955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GEV41_27960	COG0006	proline dipeptidase activity
GEV41_27965	COG3079	Belongs to the UPF0149 family
GEV41_27985	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GEV41_27995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GEV41_28000	COG1129	ABC transporter
GEV41_28000	COG0842	Transport permease protein
GEV41_28005	COG0842	Transport permease protein
GEV41_28035	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GEV41_28050	COG0248	Ppx GppA phosphatase
GEV41_28055	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GEV41_28070	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GEV41_28075	COG1671	Belongs to the UPF0178 family
GEV41_28085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GEV41_28095	COG1965	Belongs to the frataxin family
GEV41_28105	COG0019	diaminopimelate decarboxylase activity
GEV41_28110	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GEV41_28120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GEV41_28125	COG0546	phosphoglycolate phosphatase activity
GEV41_28135	COG0004	ammonium transporteR
GEV41_28140	COG0347	Belongs to the P(II) protein family
GEV41_28195	COG4566	intracellular signal transduction
GEV41_28200	COG4191	Histidine kinase
GEV41_28205	COG1335	isochorismatase
GEV41_28240	COG1335	isochorismatase
GEV41_28245	COG0583	DNA-binding transcription factor activity
GEV41_28280	COG1335	isochorismatase
GEV41_28295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_28300	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_28305	COG0583	DNA-binding transcription factor activity
GEV41_28310	COG5383	Protein conserved in bacteria
GEV41_28320	COG0534	Mate efflux family protein
GEV41_28335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GEV41_28340	COG0427	acetyl-CoA hydrolase
GEV41_28365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GEV41_28370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_28385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_28395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GEV41_28400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEV41_28410	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_28425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GEV41_28430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GEV41_28435	COG0747	negative chemotaxis
GEV41_28440	COG2003	Belongs to the UPF0758 family
GEV41_28445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GEV41_28450	COG0756	dUTP diphosphatase activity
GEV41_28455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GEV41_28460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GEV41_28465	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GEV41_28470	COG0708	Exodeoxyribonuclease III
GEV41_28480	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GEV41_28485	COG1561	YicC-like family, N-terminal region
GEV41_28490	COG0194	GDP metabolic process
GEV41_28500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GEV41_28505	COG0174	glutamine synthetase
GEV41_28515	COG1758	RNA polymerase activity
GEV41_28520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GEV41_28550	COG0848	biopolymer transport protein
GEV41_28560	COG0583	DNA-binding transcription factor activity
GEV41_28565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GEV41_28600	COG3161	chorismate lyase activity
GEV41_28605	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GEV41_28625	COG1253	flavin adenine dinucleotide binding
GEV41_28630	COG0739	heme binding
GEV41_28640	COG0704	Plays a role in the regulation of phosphate uptake
GEV41_28645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GEV41_28650	COG0581	inorganic phosphate transmembrane transporter activity
GEV41_28665	COG0477	Major facilitator Superfamily
GEV41_28670	COG1607	acyl-coa hydrolase
GEV41_28705	COG0583	DNA-binding transcription factor activity
GEV41_28710	COG1027	Aspartate ammonia-lyase
GEV41_28750	COG5016	pyruvate
GEV41_28750	COG0511	ligase activity, forming carbon-carbon bonds
GEV41_28755	COG0439	Biotin carboxylase
GEV41_28760	COG0583	DNA-binding transcription factor activity
GEV41_28775	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GEV41_28780	COG0210	DNA helicase
GEV41_28795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GEV41_28795	COG4651	solute:proton antiporter activity
GEV41_28800	COG1607	acyl-coa hydrolase
GEV41_28805	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GEV41_28815	COG0523	cobalamin synthesis protein
GEV41_28840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEV41_28845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GEV41_28850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GEV41_28875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV41_28885	COG1012	belongs to the aldehyde dehydrogenase family
GEV41_28890	COG4638	Rieske (2fe-2S)
GEV41_28905	COG0318	PFAM AMP-dependent synthetase and ligase
GEV41_28955	COG0778	Nitroreductase
GEV41_28980	COG0589	response to stress
GEV41_28995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GEV41_29005	COG0659	secondary active sulfate transmembrane transporter activity
GEV41_29060	COG0583	DNA-binding transcription factor activity
GEV41_29105	COG4644	lycopene metabolic process
GEV41_29110	COG2249	NAD(P)H dehydrogenase (quinone) activity
GEV41_29130	COG1115	amino acid carrier protein
GEV41_29140	COG0583	DNA-binding transcription factor activity
GEV41_29150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GEV41_29175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GEV41_29180	COG1984	allophanate hydrolase subunit 2
GEV41_29185	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GEV41_29190	COG0511	ligase activity, forming carbon-carbon bonds
GEV41_29195	COG0439	Biotin carboxylase
GEV41_29215	COG0583	DNA-binding transcription factor activity
GEV41_29240	COG1061	Type III restriction enzyme res subunit
GEV41_29275	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GEV41_29280	COG1349	DNA-binding transcription factor activity
GEV41_29285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GEV41_29290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GEV41_29295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GEV41_29300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GEV41_29305	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GEV41_29310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GEV41_29315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GEV41_29325	COG0356	it plays a direct role in the translocation of protons across the membrane
GEV41_29330	COG3312	ion transport
GEV41_29335	COG1475	DNA binding
GEV41_29340	COG1192	Involved in chromosome partitioning
GEV41_29345	COG0357	Ribosomal RNA small subunit methyltransferase G
GEV41_29350	COG0445	tRNA wobble uridine modification
GEV41_29355	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GEV41_29360	COG0706	membrane insertase activity
GEV41_29365	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GEV41_29370	COG0594	ribonuclease P activity
GEV41_29375	COG0230	Belongs to the bacterial ribosomal protein bL34 family