locus-tag	class	description
CH92_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CH92_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CH92_00040	COG0751	glycine-tRNA ligase activity
CH92_00045	COG0752	glycyl-tRNA synthetase alpha subunit
CH92_00050	COG2818	Glycosylase
CH92_00070	COG1126	abc transporter atp-binding protein
CH92_00075	COG0765	amino acid transport
CH92_00080	COG0765	amino acid transport
CH92_00085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH92_00090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH92_00095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH92_00100	COG2423	ornithine cyclodeaminase activity
CH92_00105	COG0006	proline dipeptidase activity
CH92_00110	COG3608	succinylglutamate desuccinylase aspartoacylase
CH92_00115	COG1522	sequence-specific DNA binding
CH92_00120	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH92_00125	COG1012	belongs to the aldehyde dehydrogenase family
CH92_00130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CH92_00135	COG0569	domain protein
CH92_00140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CH92_00145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CH92_00150	COG0242	peptide deformylase activity
CH92_00155	COG1652	LysM domain
CH92_00165	COG0009	L-threonylcarbamoyladenylate synthase
CH92_00175	COG0408	coproporphyrinogen oxidase activity
CH92_00180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH92_00195	COG1686	Belongs to the peptidase S11 family
CH92_00235	COG0662	Cupin 2, conserved barrel domain protein
CH92_00265	COG0662	Cupin 2, conserved barrel domain protein
CH92_00290	COG1132	(ABC) transporter
CH92_00300	COG3340	Belongs to the peptidase S51 family
CH92_00325	COG0625	glutathione transferase activity
CH92_00330	COG0667	Aldo Keto reductase
CH92_00355	COG0159	tryptophan synthase activity
CH92_00370	COG1404	Belongs to the peptidase S8 family
CH92_00395	COG1132	(ABC) transporter
CH92_00400	COG4249	Peptidase C14 caspase catalytic subunit p20
CH92_00405	COG3360	Dodecin
CH92_00415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH92_00455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH92_00460	COG2207	Transcriptional regulator
CH92_00470	COG0339	signal peptide processing
CH92_00500	COG0659	secondary active sulfate transmembrane transporter activity
CH92_00510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH92_00515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH92_00520	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CH92_00550	COG0109	protoheme IX farnesyltransferase activity
CH92_00565	COG3720	iron ion transport
CH92_00575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH92_00610	COG2011	ABC-type metal ion transport system permease component
CH92_00625	COG1451	nucleotide metabolic process
CH92_00630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH92_00635	COG1121	(ABC) transporter
CH92_00640	COG0735	belongs to the Fur family
CH92_00645	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH92_00660	COG1611	Belongs to the LOG family
CH92_00710	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH92_00715	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH92_00720	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH92_00725	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH92_00780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH92_00785	COG0583	DNA-binding transcription factor activity
CH92_00845	COG4191	Histidine kinase
CH92_00845	COG0784	Response regulator, receiver
CH92_00860	COG3795	YCII-related domain
CH92_00865	COG4941	Belongs to the sigma-70 factor family
CH92_00870	COG2204	response regulator
CH92_00880	COG0659	secondary active sulfate transmembrane transporter activity
CH92_00885	COG0589	response to stress
CH92_00890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH92_00910	COG3276	selenocysteine insertion sequence binding
CH92_00915	COG1921	L-seryl-tRNASec selenium transferase activity
CH92_00925	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CH92_00930	COG0210	DNA helicase
CH92_00960	COG0527	aspartate kinase activity
CH92_00965	COG5285	phytanoyl-CoA dioxygenase
CH92_00970	COG1917	Cupin 2, conserved barrel domain protein
CH92_00985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH92_01015	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_01020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH92_01035	COG0765	amino acid transport
CH92_01040	COG0765	amino acid transport
CH92_01085	COG0583	DNA-binding transcription factor activity
CH92_01090	COG0439	Biotin carboxylase
CH92_01095	COG0511	ligase activity, forming carbon-carbon bonds
CH92_01095	COG5016	pyruvate
CH92_01110	COG2066	Belongs to the glutaminase family
CH92_01135	COG0058	SHG alpha-glucan phosphorylase activity
CH92_01140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CH92_01170	COG1490	D-aminoacyl-tRNA deacylase activity
CH92_01190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH92_01195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH92_01200	COG0140	phosphoribosyl-ATP diphosphatase activity
CH92_01205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH92_01210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CH92_01220	COG2226	methyltransferase
CH92_01235	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CH92_01245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH92_01260	COG3852	Histidine kinase
CH92_01280	COG0301	tRNA thio-modification
CH92_01280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH92_01305	COG0583	DNA-binding transcription factor activity
CH92_01325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CH92_01330	COG3493	citrate carrier protein
CH92_01335	COG3290	protein histidine kinase activity
CH92_01340	COG4565	transcriptional regulatory protein
CH92_01365	COG2819	hydrolase of the alpha beta superfamily
CH92_01380	COG2207	Transcriptional regulator
CH92_01385	COG0583	DNA-binding transcription factor activity
CH92_01420	COG2203	Gaf domain
CH92_01420	COG3706	GGDEF domain
CH92_01420	COG4251	negative regulation of phosphorylation
CH92_01420	COG5001	Diguanylate cyclase
CH92_01430	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CH92_01450	COG4807	Protein conserved in bacteria
CH92_01465	COG2204	response regulator
CH92_01470	COG5001	Diguanylate cyclase
CH92_01475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH92_01510	COG4589	Belongs to the CDS family
CH92_01520	COG0351	phosphomethylpyrimidine kinase
CH92_01540	COG1320	monovalent cation:proton antiporter activity
CH92_01555	COG0651	ATP synthesis coupled electron transport
CH92_01560	COG0651	ATP synthesis coupled electron transport
CH92_01565	COG2111	Na H antiporter
CH92_01565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH92_01570	COG0840	transmembrane signaling receptor activity
CH92_01585	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_01620	COG2197	response regulator
CH92_01640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH92_01645	COG0277	FAD linked oxidase domain protein
CH92_01650	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH92_01665	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH92_01670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH92_01690	COG0494	nUDIX hydrolase
CH92_01695	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CH92_01705	COG0730	response to heat
CH92_01710	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CH92_01715	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CH92_01720	COG1192	Involved in chromosome partitioning
CH92_01730	COG0559	Belongs to the binding-protein-dependent transport system permease family
CH92_01735	COG0410	ABC transporter
CH92_01755	COG0739	heme binding
CH92_01765	COG1253	flavin adenine dinucleotide binding
CH92_01780	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CH92_01785	COG3161	chorismate lyase activity
CH92_01790	COG2186	Transcriptional regulator
CH92_01795	COG0277	FAD linked oxidase domain protein
CH92_01800	COG0277	FAD linked oxidase domain protein
CH92_01805	COG0247	lactate metabolic process
CH92_01810	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CH92_01815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH92_01820	COG1620	l-lactate permease
CH92_01860	COG5002	protein histidine kinase activity
CH92_01870	COG0583	DNA-binding transcription factor activity
CH92_01875	COG1960	acyl-CoA dehydrogenase activity
CH92_01880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_01885	COG1704	LemA family
CH92_01900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH92_01910	COG0489	protein tyrosine kinase activity
CH92_01920	COG2855	membrane
CH92_01935	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CH92_01965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH92_01980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH92_01990	COG2885	chlorophyll binding
CH92_01995	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CH92_02005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH92_02010	COG1758	RNA polymerase activity
CH92_02020	COG1561	YicC-like family, N-terminal region
CH92_02025	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CH92_02035	COG0708	Exodeoxyribonuclease III
CH92_02040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CH92_02050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CH92_02060	COG0756	dUTP diphosphatase activity
CH92_02065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH92_02070	COG2003	Belongs to the UPF0758 family
CH92_02080	COG2050	protein possibly involved in aromatic compounds catabolism
CH92_02085	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH92_02105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH92_02110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_02115	COG1522	sequence-specific DNA binding
CH92_02120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_02145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CH92_02165	COG0366	Alpha amylase catalytic
CH92_02180	COG1454	alcohol dehydrogenase
CH92_02190	COG1414	Transcriptional regulator
CH92_02205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_02210	COG0606	chelatase, subunit chli
CH92_02215	COG2960	long-chain fatty acid transporting porin activity
CH92_02220	COG0347	Belongs to the P(II) protein family
CH92_02225	COG0004	ammonium transporteR
CH92_02230	COG0004	ammonium transporteR
CH92_02235	COG0432	Pfam Uncharacterised protein family UPF0047
CH92_02250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH92_02260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CH92_02275	COG1965	Belongs to the frataxin family
CH92_02280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH92_02285	COG3072	Adenylate cyclase
CH92_02300	COG0598	Magnesium transport protein CorA
CH92_02320	COG0165	Argininosuccinate lyase
CH92_02360	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CH92_02380	COG0488	(ABC) transporter
CH92_02390	COG0861	Integral membrane protein TerC family
CH92_02400	COG1671	Belongs to the UPF0178 family
CH92_02405	COG2050	protein possibly involved in aromatic compounds catabolism
CH92_02410	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH92_02420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH92_02440	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CH92_02455	COG0018	arginyl-trna synthetase
CH92_02460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH92_02465	COG0254	rRNA binding
CH92_02475	COG0281	malic enzyme
CH92_02510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CH92_02515	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CH92_02525	COG0067	glutamate synthase
CH92_02525	COG0070	glutamate synthase
CH92_02525	COG0069	glutamate synthase activity
CH92_02530	COG0493	'glutamate synthase
CH92_02550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH92_02555	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_02565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH92_02595	COG2986	histidine ammonia-lyase
CH92_02620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH92_02625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH92_02640	COG3118	belongs to the thioredoxin family
CH92_02650	COG2814	Major facilitator Superfamily
CH92_02715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH92_02720	COG0358	DNA primase activity
CH92_02725	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CH92_02730	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CH92_02735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CH92_02755	COG2719	SpoVR family
CH92_02760	COG2718	Belongs to the UPF0229 family
CH92_02765	COG2766	serine protein kinase
CH92_02770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH92_02775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CH92_02780	COG2967	ApaG domain
CH92_02785	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CH92_02790	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CH92_02795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH92_02800	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH92_02805	COG3178	'Phosphotransferase
CH92_02810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CH92_02830	COG2197	response regulator
CH92_02835	COG3842	ATPase activity
CH92_02845	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH92_02855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH92_02860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH92_02865	COG0546	phosphoglycolate phosphatase activity
CH92_02875	COG0512	Glutamine amidotransferase of anthranilate synthase
CH92_02880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH92_02885	COG0134	indole-3-glycerol-phosphate synthase activity
CH92_02895	COG1765	OsmC-like protein
CH92_02905	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CH92_02910	COG0537	adenosine 5'-monophosphoramidase activity
CH92_02915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH92_02925	COG2070	2-Nitropropane dioxygenase
CH92_02935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH92_02940	COG0316	Belongs to the HesB IscA family
CH92_02945	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CH92_02950	COG0739	heme binding
CH92_02955	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CH92_03010	COG3501	Rhs element vgr protein
CH92_03025	COG3501	Rhs element vgr protein
CH92_03030	COG2815	serine threonine protein kinase
CH92_03030	COG0515	serine threonine protein kinase
CH92_03085	COG3501	Rhs element vgr protein
CH92_03090	COG3604	Transcriptional regulator
CH92_03165	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CH92_03165	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CH92_03170	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CH92_03220	COG0081	regulation of translation
CH92_03230	COG0222	ribosome binding
CH92_03235	COG0085	RNA polymerase activity
CH92_03240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CH92_03245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH92_03250	COG0049	tRNA binding
CH92_03255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CH92_03265	COG0051	transcription antitermination factor activity, RNA binding
CH92_03270	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CH92_03275	COG0088	Forms part of the polypeptide exit tunnel
CH92_03280	COG0089	rRNA binding
CH92_03285	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CH92_03290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH92_03300	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH92_03305	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH92_03310	COG0255	Belongs to the universal ribosomal protein uL29 family
CH92_03315	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH92_03320	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH92_03325	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CH92_03330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CH92_03335	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CH92_03340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CH92_03345	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CH92_03355	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CH92_03360	COG1841	ribosomal large subunit assembly
CH92_03365	COG0200	Binds to the 23S rRNA
CH92_03375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH92_03380	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CH92_03385	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CH92_03390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH92_03395	COG0202	RNA polymerase activity
CH92_03400	COG0203	ribosomal protein L17
CH92_03415	COG2814	Major facilitator Superfamily
CH92_03430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH92_03435	COG3047	cAMP biosynthetic process
CH92_03445	COG0811	peptide transport
CH92_03450	COG0811	peptide transport
CH92_03455	COG0848	biopolymer transport protein
CH92_03495	COG2321	neutral zinc metallopeptidase
CH92_03535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CH92_03540	COG2252	PERMEase
CH92_03555	COG2080	2 iron, 2 sulfur cluster binding
CH92_03560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CH92_03565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CH92_03580	COG0789	Transcriptional regulator
CH92_03585	COG2813	Specifically methylates the guanine in position
CH92_03600	COG3119	arylsulfatase activity
CH92_03640	COG4176	ABC-type proline glycine betaine transport system permease component
CH92_03645	COG4175	Glycine betaine
CH92_03655	COG1760	l-serine dehydratase
CH92_03680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CH92_03685	COG2181	nitrate reductase activity
CH92_03685	COG0247	lactate metabolic process
CH92_03690	COG1902	pentaerythritol trinitrate reductase activity
CH92_03690	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH92_03715	COG3246	L-lysine catabolic process to acetate
CH92_03730	COG1063	alcohol dehydrogenase
CH92_03765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH92_03765	COG1017	nitric oxide dioxygenase activity
CH92_03780	COG3265	gluconokinase activity
CH92_03785	COG3706	GGDEF domain
CH92_03805	COG0488	(ABC) transporter
CH92_03815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CH92_03855	COG1970	mechanosensitive ion channel activity
CH92_03865	COG1067	ATP-dependent peptidase activity
CH92_03875	COG2862	Uncharacterized protein family, UPF0114
CH92_03880	COG0545	Peptidyl-prolyl cis-trans isomerase
CH92_03890	COG0142	geranyltranstransferase activity
CH92_03895	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CH92_03900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CH92_03905	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CH92_03910	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CH92_03915	COG3045	CreA protein
CH92_03920	COG0268	Binds directly to 16S ribosomal RNA
CH92_03925	COG0728	peptidoglycan biosynthetic process
CH92_03930	COG0196	riboflavin kinase activity
CH92_03935	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CH92_03945	COG1047	Peptidyl-prolyl cis-trans
CH92_03950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CH92_03990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_03995	COG0023	Translation Initiation Factor
CH92_04000	COG1166	arginine decarboxylase activity
CH92_04005	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CH92_04015	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH92_04020	COG1522	sequence-specific DNA binding
CH92_04035	COG0733	neurotransmitter:sodium symporter activity
CH92_04045	COG0625	glutathione transferase activity
CH92_04050	COG0733	neurotransmitter:sodium symporter activity
CH92_04060	COG0693	protein deglycase activity
CH92_04070	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_04080	COG2154	pterin-4-alpha-carbinolamine dehydratase
CH92_04090	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CH92_04100	COG1760	l-serine dehydratase
CH92_04105	COG0492	ferredoxin-NADP+ reductase activity
CH92_04120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_04135	COG3189	MarR family transcriptional regulator
CH92_04150	COG1960	acyl-CoA dehydrogenase activity
CH92_04175	COG0517	IMP dehydrogenase activity
CH92_04175	COG1125	glycine betaine transport
CH92_04200	COG3604	Transcriptional regulator
CH92_04230	COG2814	Major facilitator Superfamily
CH92_04245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CH92_04280	COG1228	amidohydrolase
CH92_04325	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH92_04330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH92_04355	COG1063	alcohol dehydrogenase
CH92_04390	COG2423	ornithine cyclodeaminase activity
CH92_04410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH92_04415	COG1012	belongs to the aldehyde dehydrogenase family
CH92_04425	COG0028	Belongs to the TPP enzyme family
CH92_04430	COG2271	Major facilitator Superfamily
CH92_04435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH92_04450	COG0251	oxidation-reduction process
CH92_04465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_04470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_04475	COG1012	belongs to the aldehyde dehydrogenase family
CH92_04480	COG0277	FAD linked oxidase domain protein
CH92_04480	COG0247	lactate metabolic process
CH92_04485	COG0583	DNA-binding transcription factor activity
CH92_04505	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CH92_04515	COG2223	nitrite transmembrane transporter activity
CH92_04520	COG1960	acyl-CoA dehydrogenase activity
CH92_04525	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_04530	COG3038	cytochrome b561
CH92_04550	COG1620	l-lactate permease
CH92_04555	COG2186	Transcriptional regulator
CH92_04560	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CH92_04570	COG2914	Belongs to the UPF0125 (RnfH) family
CH92_04575	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH92_04585	COG0497	DNA recombination
CH92_04590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CH92_04595	COG0443	Heat shock 70 kDa protein
CH92_04600	COG0484	heat shock protein binding
CH92_04605	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CH92_04610	COG0505	Belongs to the CarA family
CH92_04635	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CH92_04640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH92_04645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH92_04650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CH92_04655	COG0149	triose-phosphate isomerase activity
CH92_04660	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH92_04675	COG0779	Required for maturation of 30S ribosomal subunits
CH92_04680	COG0195	Participates in both transcription termination and antitermination
CH92_04685	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CH92_04690	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CH92_04695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CH92_04700	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CH92_04705	COG1185	polyribonucleotide nucleotidyltransferase activity
CH92_04710	COG2823	Periplasmic or secreted lipoprotein
CH92_04740	COG0166	Belongs to the GPI family
CH92_04745	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CH92_04750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CH92_04755	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CH92_04775	COG4191	Histidine kinase
CH92_04785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH92_04790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH92_04795	COG0436	Aminotransferase
CH92_04810	COG1285	pathogenesis
CH92_04835	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_04840	COG0659	secondary active sulfate transmembrane transporter activity
CH92_04895	COG0501	Belongs to the peptidase M48B family
CH92_04905	COG2119	membrane
CH92_04910	COG2813	Specifically methylates the guanine in position
CH92_04915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_04920	COG1280	lysine exporter protein (LysE YggA)
CH92_04925	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_04930	COG0784	Response regulator, receiver
CH92_04930	COG4191	Histidine kinase
CH92_04935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH92_04940	COG2885	chlorophyll binding
CH92_04945	COG3850	Histidine kinase
CH92_04945	COG2205	protein histidine kinase activity
CH92_04945	COG3437	response regulator, receiver
CH92_04945	COG4999	Histidine kinase
CH92_04955	COG0204	Acyl-transferase
CH92_04965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CH92_04975	COG0386	Belongs to the glutathione peroxidase family
CH92_04980	COG1309	transcriptional regulator
CH92_04990	COG0655	NAD(P)H dehydrogenase (quinone) activity
CH92_04995	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH92_05015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH92_05060	COG0693	protein deglycase activity
CH92_05065	COG4628	conserved protein (DUF2132)
CH92_05075	COG3706	GGDEF domain
CH92_05110	COG0714	Associated with various cellular activities
CH92_05140	COG2925	Exonuclease
CH92_05150	COG0788	formyltetrahydrofolate deformylase activity
CH92_05160	COG0433	COG0433 Predicted ATPase
CH92_05175	COG3022	response to hydroperoxide
CH92_05185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CH92_05190	COG0315	cyclic pyranopterin monophosphate synthase activity
CH92_05195	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH92_05210	COG3706	GGDEF domain
CH92_05215	COG0400	carboxylic ester hydrolase activity
CH92_05220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH92_05225	COG4597	amino acid ABC transporter
CH92_05230	COG0765	amino acid transport
CH92_05235	COG1126	abc transporter atp-binding protein
CH92_05240	COG0047	phosphoribosylformylglycinamidine synthase activity
CH92_05240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CH92_05250	COG1764	response to oxidative stress
CH92_05255	COG1846	Transcriptional regulator
CH92_05260	COG3034	peptidoglycan biosynthetic process
CH92_05285	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CH92_05290	COG4536	flavin adenine dinucleotide binding
CH92_05295	COG4137	Cytochrome C assembly protein
CH92_05300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH92_05305	COG0228	four-way junction DNA binding
CH92_05310	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CH92_05315	COG0336	Belongs to the RNA methyltransferase TrmD family
CH92_05320	COG0335	large ribosomal subunit rRNA binding
CH92_05330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH92_05335	COG3791	Glutathione-dependent formaldehyde-activating
CH92_05350	COG1802	Transcriptional regulator
CH92_05360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_05370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_05375	COG1024	Enoyl-CoA hydratase
CH92_05385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH92_05390	COG0247	lactate metabolic process
CH92_05390	COG0277	FAD linked oxidase domain protein
CH92_05395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH92_05400	COG0418	dihydroorotase activity
CH92_05410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH92_05410	COG3008	intermembrane lipid transfer
CH92_05415	COG2995	paraquat-inducible protein a
CH92_05420	COG2995	paraquat-inducible protein a
CH92_05430	COG0137	argininosuccinate synthase activity
CH92_05435	COG0346	lactoylglutathione lyase activity
CH92_05445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH92_05455	COG4659	FMN binding
CH92_05460	COG4658	electron transport chain
CH92_05470	COG2878	Part of a membrane complex involved in electron transport
CH92_05475	COG4657	Part of a membrane complex involved in electron transport
CH92_05485	COG1024	Enoyl-CoA hydratase
CH92_05495	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CH92_05510	COG0354	folic acid binding
CH92_05515	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CH92_05545	COG3086	response to oxidative stress
CH92_05550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH92_05555	COG0481	GTPase activity
CH92_05570	COG0571	ribonuclease III activity
CH92_05575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CH92_05580	COG1381	Involved in DNA repair and RecF pathway recombination
CH92_05585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH92_05595	COG0583	DNA-binding transcription factor activity
CH92_05605	COG0500	methyltransferase
CH92_05610	COG2226	methyltransferase
CH92_05620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH92_05635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH92_05645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH92_05690	COG2856	Zn peptidase
CH92_05710	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH92_05710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH92_05715	COG0489	protein tyrosine kinase activity
CH92_05720	COG1278	Cold shock
CH92_05725	COG0717	Belongs to the dCTP deaminase family
CH92_05740	COG0583	DNA-binding transcription factor activity
CH92_05760	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CH92_05775	COG1017	nitric oxide dioxygenase activity
CH92_05775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH92_05790	COG0469	pyruvate kinase activity
CH92_05800	COG2084	Dehydrogenase
CH92_05805	COG3622	Belongs to the hyi family
CH92_05810	COG3960	tartronate-semialdehyde synthase activity
CH92_05815	COG0583	DNA-binding transcription factor activity
CH92_05820	COG2351	hydroxyisourate hydrolase activity
CH92_05840	COG0708	Exodeoxyribonuclease III
CH92_05845	COG2200	EAL domain
CH92_05845	COG2199	diguanylate cyclase activity
CH92_05845	COG3287	FIST C domain
CH92_05860	COG1538	Outer membrane efflux protein
CH92_05880	COG2207	Transcriptional regulator
CH92_05885	COG1944	ATP diphosphatase activity
CH92_05900	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CH92_05925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH92_05935	COG0784	Response regulator, receiver
CH92_05935	COG4191	Histidine kinase
CH92_05970	COG1280	lysine exporter protein (LysE YggA)
CH92_05980	COG0656	L-ascorbic acid biosynthetic process
CH92_05985	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_06015	COG2133	pyrroloquinoline quinone binding
CH92_06020	COG4993	Dehydrogenase
CH92_06025	COG2996	Protein conserved in bacteria
CH92_06045	COG0489	protein tyrosine kinase activity
CH92_06070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH92_06095	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CH92_06115	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CH92_06165	COG1295	ribonuclease BN
CH92_06190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CH92_06195	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CH92_06205	COG1546	Belongs to the CinA family
CH92_06210	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CH92_06215	COG2137	regulation of response to DNA damage stimulus
CH92_06240	COG0697	spore germination
CH92_06250	COG0583	DNA-binding transcription factor activity
CH92_06260	COG3012	SEC-C Motif Domain Protein
CH92_06280	COG1199	ATP-dependent helicase activity
CH92_06295	COG0259	pyridoxamine-phosphate oxidase activity
CH92_06305	COG3133	Outer membrane lipoprotein
CH92_06310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH92_06310	COG2111	Na H antiporter
CH92_06315	COG1006	Multisubunit Na H antiporter MnhC subunit
CH92_06320	COG0651	ATP synthesis coupled electron transport
CH92_06330	COG2212	antiporter activity
CH92_06335	COG1320	monovalent cation:proton antiporter activity
CH92_06340	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CH92_06345	COG0024	Methionine aminopeptidase
CH92_06350	COG0052	Belongs to the universal ribosomal protein uS2 family
CH92_06355	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CH92_06360	COG0528	UMP kinase activity
CH92_06365	COG0233	cytoplasmic translational termination
CH92_06370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CH92_06380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CH92_06390	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH92_06405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH92_06410	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH92_06415	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH92_06420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CH92_06430	COG0825	malonyl-CoA metabolic process
CH92_06435	COG0037	tRNA processing
CH92_06440	COG0504	CTP synthase activity
CH92_06445	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CH92_06450	COG0148	phosphopyruvate hydratase activity
CH92_06475	COG0583	DNA-binding transcription factor activity
CH92_06480	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CH92_06490	COG1902	pentaerythritol trinitrate reductase activity
CH92_06495	COG0640	Transcriptional regulator
CH92_06500	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CH92_06505	COG0585	pseudouridine synthase activity
CH92_06510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CH92_06515	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CH92_06560	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH92_06575	COG1403	HNH endonuclease
CH92_06580	COG0217	transcriptional regulatory protein
CH92_06585	COG0697	spore germination
CH92_06595	COG0840	transmembrane signaling receptor activity
CH92_06605	COG0004	ammonium transporteR
CH92_06625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH92_06630	COG1309	transcriptional regulator
CH92_06635	COG0625	glutathione transferase activity
CH92_06660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH92_06665	COG0348	domain, Protein
CH92_06680	COG1346	cytolysis
CH92_06685	COG0596	Alpha beta hydrolase
CH92_06690	COG0655	NAD(P)H dehydrogenase (quinone) activity
CH92_06700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CH92_06705	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH92_06720	COG1805	sodium ion transport
CH92_06735	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH92_06745	COG1477	protein flavinylation
CH92_06755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH92_06760	COG0584	glycerophosphoryl diester phosphodiesterase
CH92_06775	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH92_06780	COG1136	(ABC) transporter
CH92_06785	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH92_06795	COG0658	competence protein
CH92_06795	COG2333	competence protein COMEC
CH92_06800	COG0811	peptide transport
CH92_06810	COG1663	tetraacyldisaccharide 4'-kinase activity
CH92_06815	COG2835	tetraacyldisaccharide 4'-kinase activity
CH92_06820	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CH92_06825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CH92_06830	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH92_06845	COG1530	ribonuclease E activity
CH92_06855	COG0546	phosphoglycolate phosphatase activity
CH92_06860	COG0616	signal peptide processing
CH92_06860	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CH92_06865	COG0424	maF-like protein
CH92_06870	COG1399	metal-binding, possibly nucleic acid-binding protein
CH92_06875	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH92_06880	COG0416	fatty acid biosynthetic process
CH92_06895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH92_06900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH92_06910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH92_06915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CH92_06930	COG0084	hydrolase, TatD family'
CH92_06935	COG1113	amino acid transport
CH92_06965	COG2226	methyltransferase
CH92_06970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CH92_06975	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH92_06980	COG2166	iron-sulfur cluster assembly
CH92_06985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH92_06990	COG2171	N-acyltransferase activity
CH92_06995	COG1393	Belongs to the ArsC family
CH92_07015	COG0436	Aminotransferase
CH92_07030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH92_07035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CH92_07045	COG0628	permease
CH92_07065	COG1393	Belongs to the ArsC family
CH92_07070	COG1295	ribonuclease BN
CH92_07090	COG0442	prolyl-tRNA aminoacylation
CH92_07105	COG2900	Belongs to the SlyX family
CH92_07115	COG0783	Belongs to the Dps family
CH92_07120	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CH92_07130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CH92_07135	COG0632	four-way junction helicase activity
CH92_07140	COG2255	four-way junction helicase activity
CH92_07145	COG0824	Thioesterase
CH92_07165	COG0823	Involved in the tonB-independent uptake of proteins
CH92_07170	COG2885	chlorophyll binding
CH92_07175	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH92_07185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CH92_07195	COG0427	acetyl-CoA hydrolase
CH92_07205	COG4783	chaperone-mediated protein folding
CH92_07210	COG0425	Belongs to the sulfur carrier protein TusA family
CH92_07220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH92_07230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH92_07240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CH92_07270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_07295	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CH92_07365	COG2205	protein histidine kinase activity
CH92_07395	COG4580	involved in the transport of maltose and maltodextrins
CH92_07405	COG0583	DNA-binding transcription factor activity
CH92_07410	COG3485	protocatechuate 3,4-dioxygenase
CH92_07415	COG3485	protocatechuate 3,4-dioxygenase
CH92_07420	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH92_07425	COG0679	Auxin Efflux Carrier
CH92_07435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH92_07445	COG0366	Alpha amylase catalytic
CH92_07455	COG1175	transmembrane transport
CH92_07460	COG3833	ABC-type maltose transport systems, permease component
CH92_07465	COG2909	trisaccharide binding
CH92_07480	COG0366	Alpha amylase catalytic
CH92_07490	COG2076	Multidrug Resistance protein
CH92_07495	COG0385	Bile acid
CH92_07500	COG2974	May be involved in recombination
CH92_07515	COG0545	Peptidyl-prolyl cis-trans isomerase
CH92_07535	COG0556	nucleotide-excision repair
CH92_07550	COG0583	DNA-binding transcription factor activity
CH92_07555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH92_07600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CH92_07620	COG2814	Major facilitator Superfamily
CH92_07625	COG3091	SprT-like family
CH92_07645	COG0037	tRNA processing
CH92_07650	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH92_07655	COG2818	Glycosylase
CH92_07665	COG0791	NLP P60 protein
CH92_07670	COG0791	NLP P60 protein
CH92_07680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH92_07695	COG4206	TonB-dependent receptor
CH92_07710	COG1797	cobyrinic acid a,c-diamide synthase activity
CH92_07715	COG0778	Nitroreductase
CH92_07720	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CH92_07730	COG1492	cobalamin metabolic process
CH92_07740	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CH92_07745	COG0406	alpha-ribazole phosphatase activity
CH92_07750	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CH92_07780	COG2067	long-chain fatty acid transport protein
CH92_07795	COG3100	YcgL domain-containing protein
CH92_07800	COG2983	Belongs to the UPF0260 family
CH92_07810	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH92_07815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CH92_07820	COG0527	aspartate kinase activity
CH92_07825	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH92_07850	COG2239	Acts as a magnesium transporter
CH92_07860	COG0511	ligase activity, forming carbon-carbon bonds
CH92_07860	COG5016	pyruvate
CH92_07865	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CH92_07890	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CH92_07910	COG0784	Response regulator, receiver
CH92_07910	COG0835	chemotaxis
CH92_07915	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH92_07920	COG1815	bacterial-type flagellum-dependent cell motility
CH92_07925	COG1558	bacterial-type flagellum-dependent cell motility
CH92_07930	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH92_07935	COG1749	Flagellar hook protein flgE
CH92_07940	COG4787	bacterial-type flagellum-dependent cell motility
CH92_07945	COG4786	Flagellar basal body rod
CH92_07950	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CH92_07955	COG1706	bacterial-type flagellum-dependent cell motility
CH92_07965	COG1256	bacterial-type flagellum assembly
CH92_07975	COG1555	photosystem II stabilization
CH92_08000	COG2200	EAL domain
CH92_08010	COG1362	aminopeptidase activity
CH92_08015	COG0564	pseudouridine synthase activity
CH92_08020	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH92_08025	COG2894	cell division
CH92_08030	COG0850	regulation of cytokinetic process
CH92_08035	COG1560	Kdo2-lipid A biosynthetic process
CH92_08045	COG2853	Lipoprotein
CH92_08060	COG3162	membrane
CH92_08065	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH92_08095	COG3089	Belongs to the UPF0270 family
CH92_08105	COG1363	Peptidase, m42
CH92_08115	COG0367	asparagine synthase
CH92_08120	COG0583	DNA-binding transcription factor activity
CH92_08130	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CH92_08130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_08140	COG0183	Belongs to the thiolase family
CH92_08145	COG0114	fumarate hydratase activity
CH92_08155	COG0271	Belongs to the BolA IbaG family
CH92_08175	COG0840	transmembrane signaling receptor activity
CH92_08200	COG0583	DNA-binding transcription factor activity
CH92_08205	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CH92_08210	COG1960	acyl-CoA dehydrogenase activity
CH92_08220	COG2079	MmgE PrpD family protein
CH92_08230	COG2301	Belongs to the HpcH HpaI aldolase family
CH92_08250	COG1131	(ABC) transporter
CH92_08255	COG0842	Transport permease protein
CH92_08270	COG2853	Lipoprotein
CH92_08280	COG0745	RESPONSE REGULATOR receiver
CH92_08290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH92_08295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH92_08310	COG3181	Tripartite tricarboxylate transporter family receptor
CH92_08315	COG0028	Belongs to the TPP enzyme family
CH92_08320	COG0583	DNA-binding transcription factor activity
CH92_08325	COG0596	Alpha beta hydrolase
CH92_08335	COG0587	DNA-directed DNA polymerase activity
CH92_08340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CH92_08355	COG0450	alkyl hydroperoxide reductase
CH92_08360	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CH92_08370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CH92_08375	COG1605	Chorismate mutase
CH92_08375	COG0077	Prephenate dehydratase
CH92_08385	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CH92_08390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CH92_08405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH92_08410	COG0625	glutathione transferase activity
CH92_08415	COG0302	gtp cyclohydrolase
CH92_08420	COG2840	Smr protein MutS2
CH92_08450	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CH92_08460	COG0235	Class ii aldolase
CH92_08465	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CH92_08470	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CH92_08490	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH92_08495	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CH92_08505	COG0583	DNA-binding transcription factor activity
CH92_08520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH92_08530	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CH92_08535	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CH92_08550	COG0573	inorganic phosphate transmembrane transporter activity
CH92_08565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CH92_08570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH92_08580	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH92_08605	COG0348	domain, Protein
CH92_08610	COG2010	Cytochrome c
CH92_08625	COG3278	Belongs to the heme-copper respiratory oxidase family
CH92_08640	COG3278	Belongs to the heme-copper respiratory oxidase family
CH92_08650	COG0840	transmembrane signaling receptor activity
CH92_08660	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CH92_08675	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH92_08695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH92_08700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH92_08710	COG3115	cell septum assembly
CH92_08715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CH92_08730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CH92_08770	COG2009	succinate dehydrogenase
CH92_08775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH92_08780	COG1053	succinate dehydrogenase
CH92_08785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH92_08805	COG0045	succinate-CoA ligase (ADP-forming) activity
CH92_08855	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CH92_08865	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH92_08870	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CH92_08905	COG0628	permease
CH92_08915	COG0709	Synthesizes selenophosphate from selenide and ATP
CH92_08920	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CH92_08930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH92_08935	COG0714	Associated with various cellular activities
CH92_08960	COG0084	hydrolase, TatD family'
CH92_08965	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CH92_08990	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH92_08995	COG4181	ATPase activity
CH92_09025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH92_09030	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH92_09045	COG0560	Phosphoserine phosphatase
CH92_09070	COG1802	Transcriptional regulator
CH92_09080	COG0372	Belongs to the citrate synthase family
CH92_09095	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CH92_09105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH92_09120	COG0668	transmembrane transport
CH92_09150	COG2153	protein acetylation
CH92_09155	COG2850	peptidyl-arginine hydroxylation
CH92_09165	COG2915	High frequency lysogenization protein hflD homolog
CH92_09170	COG0482	sulfurtransferase activity
CH92_09190	COG1278	Cold shock
CH92_09195	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CH92_09200	COG0542	response to heat
CH92_09205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH92_09210	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CH92_09215	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CH92_09220	COG0492	ferredoxin-NADP+ reductase activity
CH92_09230	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CH92_09235	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH92_09240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH92_09245	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CH92_09250	COG1648	precorrin-2 dehydrogenase activity
CH92_09250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CH92_09255	COG0435	Glutathione S-transferase
CH92_09260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH92_09265	COG2920	part of a sulfur-relay system
CH92_09295	COG0697	spore germination
CH92_09300	COG2814	Major facilitator Superfamily
CH92_09320	COG0437	4 iron, 4 sulfur cluster binding
CH92_09360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH92_09365	COG1845	cytochrome c oxidase, subunit III
CH92_09380	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_09385	COG0723	plastoquinol--plastocyanin reductase activity
CH92_09390	COG2999	glutathione oxidoreductase activity
CH92_09410	COG3383	formate dehydrogenase (NAD+) activity
CH92_09430	COG1595	DNA-templated transcription, initiation
CH92_09440	COG3220	belongs to the UPF0276 family
CH92_09455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH92_09480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_09485	COG0372	Belongs to the citrate synthase family
CH92_09515	COG0402	S-adenosylhomocysteine deaminase activity
CH92_09520	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_09530	COG1116	anion transmembrane transporter activity
CH92_09535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH92_09545	COG1802	Transcriptional regulator
CH92_09550	COG0154	amidase activity
CH92_09575	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_09580	COG2995	paraquat-inducible protein a
CH92_09585	COG2995	paraquat-inducible protein a
CH92_09590	COG3008	intermembrane lipid transfer
CH92_09625	COG0697	spore germination
CH92_09630	COG3284	Transcriptional regulator
CH92_09635	COG1012	belongs to the aldehyde dehydrogenase family
CH92_09645	COG4772	TonB-dependent receptor
CH92_09660	COG0840	transmembrane signaling receptor activity
CH92_09685	COG3121	Chaperone
CH92_09710	COG0643	Histidine kinase
CH92_09710	COG2198	Histidine kinase
CH92_09715	COG0840	transmembrane signaling receptor activity
CH92_09720	COG0835	chemotaxis
CH92_09725	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH92_09730	COG2201	protein-glutamate methylesterase activity
CH92_09735	COG2197	response regulator
CH92_09740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH92_09750	COG3813	Protein conserved in bacteria
CH92_09755	COG2205	protein histidine kinase activity
CH92_09765	COG0784	Response regulator, receiver
CH92_09765	COG4191	Histidine kinase
CH92_09790	COG0183	Belongs to the thiolase family
CH92_09795	COG0784	Response regulator, receiver
CH92_09795	COG0835	chemotaxis
CH92_09805	COG0417	DNA replication proofreading
CH92_09840	COG2172	sigma factor antagonist activity
CH92_09845	COG1366	Belongs to the anti-sigma-factor antagonist family
CH92_09850	COG1366	Belongs to the anti-sigma-factor antagonist family
CH92_09860	COG4991	sh3 domain protein
CH92_09875	COG0515	serine threonine protein kinase
CH92_09875	COG2815	serine threonine protein kinase
CH92_09880	COG2116	formate transmembrane transporter activity
CH92_09890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH92_09890	COG2146	nitrite reductase [NAD(P)H] activity
CH92_09895	COG4989	oxidoreductase activity
CH92_09905	COG2130	NADP-dependent
CH92_09960	COG2423	ornithine cyclodeaminase activity
CH92_09975	COG1741	Belongs to the pirin family
CH92_09980	COG0583	DNA-binding transcription factor activity
CH92_09990	COG2814	Major facilitator Superfamily
CH92_10005	COG2223	nitrite transmembrane transporter activity
CH92_10010	COG2207	Transcriptional regulator
CH92_10020	COG2207	Transcriptional regulator
CH92_10035	COG3268	Saccharopine dehydrogenase
CH92_10040	COG1309	transcriptional regulator
CH92_10045	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_10065	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CH92_10115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH92_10120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH92_10120	COG0473	3-isopropylmalate dehydrogenase activity
CH92_10140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH92_10145	COG0583	DNA-binding transcription factor activity
CH92_10165	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH92_10165	COG1902	pentaerythritol trinitrate reductase activity
CH92_10170	COG2375	cellular response to nickel ion
CH92_10185	COG1335	isochorismatase
CH92_10210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CH92_10225	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH92_10230	COG0625	glutathione transferase activity
CH92_10255	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CH92_10280	COG1696	Membrane protein involved in D-alanine export
CH92_10295	COG2031	fatty acid transporter
CH92_10310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CH92_10315	COG0583	DNA-binding transcription factor activity
CH92_10325	COG0784	Response regulator, receiver
CH92_10325	COG4191	Histidine kinase
CH92_10330	COG1414	Transcriptional regulator
CH92_10335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CH92_10340	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CH92_10350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CH92_10360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CH92_10365	COG0025	NhaP-type Na H and K H
CH92_10390	COG0583	DNA-binding transcription factor activity
CH92_10410	COG0251	oxidation-reduction process
CH92_10415	COG1609	Transcriptional regulator
CH92_10420	COG0673	inositol 2-dehydrogenase activity
CH92_10430	COG2211	Major facilitator Superfamily
CH92_10445	COG0024	Methionine aminopeptidase
CH92_10460	COG0596	Alpha beta hydrolase
CH92_10465	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_10485	COG4191	Histidine kinase
CH92_10490	COG0745	RESPONSE REGULATOR receiver
CH92_10495	COG4566	intracellular signal transduction
CH92_10500	COG0583	DNA-binding transcription factor activity
CH92_10510	COG2814	Major facilitator Superfamily
CH92_10515	COG1335	isochorismatase
CH92_10530	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CH92_10535	COG3224	Antibiotic biosynthesis monooxygenase
CH92_10550	COG1335	isochorismatase
CH92_10565	COG1017	nitric oxide dioxygenase activity
CH92_10565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH92_10570	COG0625	glutathione transferase activity
CH92_10580	COG0583	DNA-binding transcription factor activity
CH92_10590	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_10605	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_10615	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CH92_10625	COG0789	Transcriptional regulator
CH92_10660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CH92_10665	COG1960	acyl-CoA dehydrogenase activity
CH92_10670	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_10710	COG1024	Enoyl-CoA hydratase
CH92_10735	COG1960	acyl-CoA dehydrogenase activity
CH92_10740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_10750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_10755	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_10760	COG1960	acyl-CoA dehydrogenase activity
CH92_10765	COG1024	Enoyl-CoA hydratase
CH92_10795	COG4221	oxidoreductase activity
CH92_10825	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CH92_10840	COG4294	response to UV
CH92_10845	COG0210	DNA helicase
CH92_10850	COG0625	glutathione transferase activity
CH92_10855	COG0583	DNA-binding transcription factor activity
CH92_10865	COG2076	Multidrug Resistance protein
CH92_10870	COG1802	Transcriptional regulator
CH92_10880	COG0765	amino acid transport
CH92_10885	COG0765	amino acid transport
CH92_10890	COG1126	abc transporter atp-binding protein
CH92_10900	COG0415	Belongs to the DNA photolyase family
CH92_10905	COG3272	Protein of unknown function (DUF1722)
CH92_10910	COG1090	epimerase
CH92_10915	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CH92_10925	COG1366	Belongs to the anti-sigma-factor antagonist family
CH92_10930	COG0789	Transcriptional regulator
CH92_10935	COG1025	Belongs to the peptidase M16 family
CH92_10940	COG3706	GGDEF domain
CH92_10960	COG2323	membrane
CH92_10975	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH92_10980	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CH92_10990	COG0535	radical SAM domain protein
CH92_11005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CH92_11010	COG1742	UPF0060 membrane protein
CH92_11015	COG0431	NADPH-dependent FMN reductase
CH92_11020	COG0640	Transcriptional regulator
CH92_11025	COG0798	PFAM Bile acid sodium symporter
CH92_11035	COG0322	excinuclease ABC activity
CH92_11100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_11110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH92_11140	COG3181	Tripartite tricarboxylate transporter family receptor
CH92_11150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH92_11155	COG1012	belongs to the aldehyde dehydrogenase family
CH92_11165	COG2721	sulfolactate sulfo-lyase activity
CH92_11170	COG0277	FAD linked oxidase domain protein
CH92_11175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_11185	COG0277	FAD linked oxidase domain protein
CH92_11230	COG2847	Copper chaperone PCu(A)C
CH92_11235	COG2149	membrane
CH92_11285	COG0583	DNA-binding transcription factor activity
CH92_11310	COG3685	Protein conserved in bacteria
CH92_11315	COG3264	Mechanosensitive ion channel
CH92_11315	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CH92_11325	COG0297	glycogen (starch) synthase activity
CH92_11330	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CH92_11335	COG1640	4-alpha-glucanotransferase
CH92_11365	COG3384	dioxygenase
CH92_11370	COG0583	DNA-binding transcription factor activity
CH92_11385	COG3568	Endonuclease Exonuclease Phosphatase
CH92_11390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH92_11395	COG0392	lysyltransferase activity
CH92_11400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CH92_11405	COG0366	Alpha amylase catalytic
CH92_11425	COG2864	formate dehydrogenase
CH92_11430	COG0437	4 iron, 4 sulfur cluster binding
CH92_11435	COG0243	molybdopterin cofactor binding
CH92_11435	COG3383	formate dehydrogenase (NAD+) activity
CH92_11440	COG3383	formate dehydrogenase (NAD+) activity
CH92_11440	COG0243	molybdopterin cofactor binding
CH92_11450	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CH92_11455	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_11490	COG1538	Outer membrane efflux protein
CH92_11515	COG0728	peptidoglycan biosynthetic process
CH92_11520	COG5642	Protein of unknown function (DUF2384)
CH92_11550	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH92_11550	COG1024	Enoyl-CoA hydratase
CH92_11565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_11580	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_11585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_11595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_11600	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CH92_11605	COG1012	belongs to the aldehyde dehydrogenase family
CH92_11610	COG0583	DNA-binding transcription factor activity
CH92_11615	COG0163	prenyltransferase activity
CH92_11650	COG2203	Gaf domain
CH92_11650	COG2199	diguanylate cyclase activity
CH92_11670	COG5002	protein histidine kinase activity
CH92_11670	COG0784	Response regulator, receiver
CH92_11695	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_11735	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CH92_11750	COG0395	ABC-type sugar transport system, permease component
CH92_11760	COG3842	ATPase activity
CH92_11770	COG3284	Transcriptional regulator
CH92_11775	COG0215	cysteine-tRNA ligase activity
CH92_11780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH92_11785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH92_11790	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH92_11820	COG0488	(ABC) transporter
CH92_11825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CH92_11835	COG1278	Cold shock
CH92_11840	COG1968	undecaprenyl-diphosphatase activity
CH92_11845	COG0840	transmembrane signaling receptor activity
CH92_11865	COG2323	membrane
CH92_11880	COG3706	GGDEF domain
CH92_11885	COG0745	RESPONSE REGULATOR receiver
CH92_11890	COG0316	Belongs to the HesB IscA family
CH92_11890	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CH92_11910	COG0697	spore germination
CH92_11925	COG2223	nitrite transmembrane transporter activity
CH92_11930	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CH92_11935	COG2815	serine threonine protein kinase
CH92_11935	COG0515	serine threonine protein kinase
CH92_11965	COG0604	alcohol dehydrogenase
CH92_11970	COG0616	signal peptide processing
CH92_11990	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_12015	COG2816	NAD+ diphosphatase activity
CH92_12025	COG1024	Enoyl-CoA hydratase
CH92_12030	COG1982	Orn Lys Arg decarboxylase major
CH92_12035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH92_12040	COG0328	RNA-DNA hybrid ribonuclease activity
CH92_12055	COG0741	lytic transglycosylase activity
CH92_12055	COG1388	LysM domain
CH92_12065	COG4166	transmembrane transport
CH92_12075	COG4174	ABC transporter (Permease)
CH92_12080	COG4239	(ABC) transporter, permease
CH92_12085	COG4172	Belongs to the ABC transporter superfamily
CH92_12095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH92_12105	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH92_12110	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CH92_12120	COG0544	peptidyl-prolyl cis-trans isomerase activity
CH92_12125	COG2259	Doxx family
CH92_12135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_12145	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_12160	COG1115	amino acid carrier protein
CH92_12165	COG2911	Protein conserved in bacteria
CH92_12170	COG0729	surface antigen
CH92_12180	COG0708	Exodeoxyribonuclease III
CH92_12185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH92_12205	COG1175	transmembrane transport
CH92_12225	COG1070	Carbohydrate kinase
CH92_12240	COG1609	Transcriptional regulator
CH92_12245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_12250	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_12255	COG3265	gluconokinase activity
CH92_12260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH92_12265	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH92_12280	COG2056	Na+-H+ antiporter family
CH92_12285	COG0720	synthase
CH92_12325	COG0402	S-adenosylhomocysteine deaminase activity
CH92_12330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH92_12335	COG0546	phosphoglycolate phosphatase activity
CH92_12340	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_12345	COG3706	GGDEF domain
CH92_12345	COG0745	RESPONSE REGULATOR receiver
CH92_12365	COG0800	Aldolase
CH92_12380	COG1737	Transcriptional regulator
CH92_12395	COG3842	ATPase activity
CH92_12410	COG1653	transport
CH92_12420	COG2205	protein histidine kinase activity
CH92_12425	COG0745	RESPONSE REGULATOR receiver
CH92_12450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CH92_12460	COG0180	Tryptophanyl-tRNA synthetase
CH92_12465	COG0009	L-threonylcarbamoyladenylate synthase
CH92_12470	COG0613	PHP domain protein
CH92_12475	COG2917	probably involved in intracellular septation
CH92_12480	COG2350	Protein conserved in bacteria
CH92_12490	COG0745	RESPONSE REGULATOR receiver
CH92_12505	COG0778	Nitroreductase
CH92_12510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH92_12515	COG0590	tRNA wobble adenosine to inosine editing
CH92_12520	COG2354	Protein conserved in bacteria
CH92_12535	COG2207	Transcriptional regulator
CH92_12560	COG1012	belongs to the aldehyde dehydrogenase family
CH92_12580	COG1752	Esterase of the alpha-beta hydrolase superfamily
CH92_12590	COG1846	Transcriptional regulator
CH92_12595	COG0514	ATP-dependent DNA helicase (RecQ)
CH92_12605	COG2832	Protein of unknown function (DUF454)
CH92_12620	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CH92_12635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CH92_12665	COG0121	glutamine amidotransferase
CH92_12675	COG0589	response to stress
CH92_12690	COG0741	lytic transglycosylase activity
CH92_12695	COG0633	Ferredoxin
CH92_12695	COG3217	Mosc domain protein beta barrel domain protein
CH92_12715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CH92_12745	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH92_12770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_12825	COG2003	Belongs to the UPF0758 family
CH92_12860	COG1201	RNA secondary structure unwinding
CH92_12885	COG0515	serine threonine protein kinase
CH92_12905	COG0072	phenylalanine-tRNA ligase activity
CH92_12910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CH92_12915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CH92_12920	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CH92_12925	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CH92_12930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CH92_12940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_12965	COG0303	'Molybdopterin
CH92_12970	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH92_13025	COG3171	Protein conserved in bacteria
CH92_13030	COG2027	D-alanyl-D-alanine carboxypeptidase
CH92_13035	COG0116	Belongs to the methyltransferase superfamily
CH92_13035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CH92_13040	COG3130	regulation of translation
CH92_13045	COG0167	dihydroorotate dehydrogenase activity
CH92_13065	COG0714	Associated with various cellular activities
CH92_13095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH92_13100	COG3707	response regulator
CH92_13105	COG1116	anion transmembrane transporter activity
CH92_13105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH92_13110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH92_13115	COG1116	anion transmembrane transporter activity
CH92_13135	COG2223	nitrite transmembrane transporter activity
CH92_13150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH92_13155	COG2146	nitrite reductase [NAD(P)H] activity
CH92_13160	COG0243	molybdopterin cofactor binding
CH92_13170	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH92_13175	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH92_13195	COG1034	ATP synthesis coupled electron transport
CH92_13200	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CH92_13205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH92_13215	COG0713	ATP synthesis coupled electron transport
CH92_13230	COG1007	ATP synthesis coupled electron transport
CH92_13245	COG0308	aminopeptidase N
CH92_13265	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CH92_13270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH92_13305	COG1902	pentaerythritol trinitrate reductase activity
CH92_13305	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH92_13330	COG1294	oxidase, subunit
CH92_13335	COG1271	oxidase subunit
CH92_13365	COG1286	toxin biosynthetic process
CH92_13370	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH92_13375	COG0285	dihydrofolate synthase activity
CH92_13380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CH92_13385	COG0135	phosphoribosylanthranilate isomerase activity
CH92_13415	COG0066	3-isopropylmalate dehydratase activity
CH92_13420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CH92_13445	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_13510	COG0438	transferase activity, transferring glycosyl groups
CH92_13555	COG0745	RESPONSE REGULATOR receiver
CH92_13560	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CH92_13565	COG3706	GGDEF domain
CH92_13565	COG0745	RESPONSE REGULATOR receiver
CH92_13570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CH92_13580	COG1309	transcriptional regulator
CH92_13610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH92_13620	COG4221	oxidoreductase activity
CH92_13655	COG0387	Pfam Sodium calcium exchanger
CH92_13675	COG1012	belongs to the aldehyde dehydrogenase family
CH92_13680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_13700	COG0653	protein targeting
CH92_13730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CH92_13765	COG0183	Belongs to the thiolase family
CH92_13770	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH92_13770	COG1024	Enoyl-CoA hydratase
CH92_13775	COG1770	oligopeptidase
CH92_13785	COG2988	succinylglutamate desuccinylase activity
CH92_13795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CH92_13820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH92_13825	COG0668	transmembrane transport
CH92_13830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CH92_13835	COG4325	translation initiation factor activity
CH92_13845	COG0583	DNA-binding transcription factor activity
CH92_13850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_13855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CH92_13860	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
CH92_13875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH92_13890	COG0438	transferase activity, transferring glycosyl groups
CH92_13900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CH92_13915	COG0463	Glycosyl transferase, family 2
CH92_13920	COG0463	Glycosyl transferase, family 2
CH92_13930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH92_13935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH92_13940	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CH92_13945	COG0776	regulation of translation
CH92_13960	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CH92_13965	COG0471	metal ion transport
CH92_13970	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CH92_13985	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CH92_14010	COG0625	glutathione transferase activity
CH92_14020	COG0386	Belongs to the glutathione peroxidase family
CH92_14025	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CH92_14030	COG0436	Aminotransferase
CH92_14040	COG0501	Belongs to the peptidase M48B family
CH92_14045	COG0500	methyltransferase
CH92_14050	COG2204	response regulator
CH92_14055	COG3852	Histidine kinase
CH92_14060	COG2204	response regulator
CH92_14090	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CH92_14125	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH92_14140	COG0835	chemotaxis
CH92_14150	COG1192	Involved in chromosome partitioning
CH92_14155	COG1360	Flagellar Motor Protein
CH92_14160	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH92_14165	COG2201	protein-glutamate methylesterase activity
CH92_14170	COG0643	Histidine kinase
CH92_14170	COG2198	Histidine kinase
CH92_14175	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH92_14190	COG0455	bacterial-type flagellum organization
CH92_14210	COG2032	superoxide dismutase activity
CH92_14225	COG1987	bacterial-type flagellum assembly
CH92_14250	COG1580	Controls the rotational direction of flagella during chemotaxis
CH92_14265	COG0745	RESPONSE REGULATOR receiver
CH92_14300	COG1677	Flagellar hook-basal body complex protein FliE
CH92_14305	COG3135	benzoate transporter
CH92_14310	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_14315	COG2130	NADP-dependent
CH92_14330	COG3300	MHYT domain
CH92_14330	COG5001	Diguanylate cyclase
CH92_14340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH92_14375	COG1278	Cold shock
CH92_14395	COG2937	Belongs to the GPAT DAPAT family
CH92_14415	COG1272	protein, Hemolysin III
CH92_14450	COG2132	Multicopper oxidase
CH92_14470	COG2943	transferase activity, transferring hexosyl groups
CH92_14475	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CH92_14500	COG1793	dna ligase
CH92_14505	COG1201	RNA secondary structure unwinding
CH92_14540	COG3956	TIGRFAM MazG family protein
CH92_14545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH92_14550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CH92_14560	COG0405	Gamma-glutamyltransferase
CH92_14565	COG0784	Response regulator, receiver
CH92_14565	COG2205	protein histidine kinase activity
CH92_14565	COG5002	protein histidine kinase activity
CH92_14570	COG2860	membrane
CH92_14585	COG2205	protein histidine kinase activity
CH92_14590	COG0745	RESPONSE REGULATOR receiver
CH92_14595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH92_14595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CH92_14600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH92_14650	COG0697	spore germination
CH92_14655	COG0583	DNA-binding transcription factor activity
CH92_14660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CH92_14680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_14685	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CH92_14690	COG2226	methyltransferase
CH92_14715	COG1733	regulation of RNA biosynthetic process
CH92_14730	COG3300	MHYT domain
CH92_14730	COG5001	Diguanylate cyclase
CH92_14750	COG0840	transmembrane signaling receptor activity
CH92_14760	COG3192	ethanolamine utilization protein
CH92_14775	COG0492	ferredoxin-NADP+ reductase activity
CH92_14825	COG4771	TonB-dependent receptor
CH92_14845	COG3459	Glycosyltransferase 36 associated
CH92_14855	COG4774	siderophore transport
CH92_14860	COG0826	peptidase U32
CH92_14885	COG4774	siderophore transport
CH92_14890	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH92_14905	COG2814	Major facilitator Superfamily
CH92_14915	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_14930	COG1846	Transcriptional regulator
CH92_14940	COG1566	PFAM secretion protein HlyD family protein
CH92_14945	COG2814	Major facilitator Superfamily
CH92_14950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH92_14970	COG0069	glutamate synthase activity
CH92_14980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH92_14995	COG1283	sodium-dependent phosphate transmembrane transporter activity
CH92_15005	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH92_15015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH92_15040	COG0668	transmembrane transport
CH92_15050	COG0483	inositol monophosphate 1-phosphatase activity
CH92_15070	COG0742	ribosomal rna small subunit methyltransferase
CH92_15080	COG1801	Protein of unknown function DUF72
CH92_15090	COG1214	PFAM Peptidase M22, glycoprotease
CH92_15105	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CH92_15135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH92_15140	COG0235	Class ii aldolase
CH92_15145	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_15175	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CH92_15185	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_15195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CH92_15210	COG1902	pentaerythritol trinitrate reductase activity
CH92_15215	COG3383	formate dehydrogenase (NAD+) activity
CH92_15220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH92_15230	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CH92_15235	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CH92_15240	COG1984	allophanate hydrolase subunit 2
CH92_15245	COG1914	H( )-stimulated, divalent metal cation uptake system
CH92_15250	COG4681	YaeQ
CH92_15255	COG2906	2 iron, 2 sulfur cluster binding
CH92_15265	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH92_15275	COG3842	ATPase activity
CH92_15280	COG0590	tRNA wobble adenosine to inosine editing
CH92_15295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CH92_15295	COG0519	Catalyzes the synthesis of GMP from XMP
CH92_15310	COG1570	exodeoxyribonuclease VII activity
CH92_15315	COG0741	lytic transglycosylase activity
CH92_15315	COG0739	heme binding
CH92_15315	COG1196	nuclear chromosome segregation
CH92_15325	COG0668	transmembrane transport
CH92_15330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CH92_15335	COG1064	alcohol dehydrogenase
CH92_15345	COG2356	endonuclease I
CH92_15350	COG3647	Membrane
CH92_15365	COG0436	Aminotransferase
CH92_15370	COG1160	GTP binding
CH92_15380	COG2976	Protein conserved in bacteria
CH92_15385	COG0124	histidyl-tRNA synthetase
CH92_15390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CH92_15405	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CH92_15410	COG0105	UTP biosynthetic process
CH92_15425	COG0443	Heat shock 70 kDa protein
CH92_15430	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH92_15435	COG0316	Belongs to the HesB IscA family
CH92_15445	COG1104	cysteine desulfurase activity
CH92_15470	COG3134	Outer membrane lipoprotein
CH92_15485	COG1862	Preprotein translocase
CH92_15505	COG1278	Cold shock
CH92_15515	COG0795	lipopolysaccharide-transporting ATPase activity
CH92_15520	COG0795	lipopolysaccharide-transporting ATPase activity
CH92_15525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CH92_15555	COG0477	Major facilitator Superfamily
CH92_15560	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CH92_15585	COG3081	Nucleoid-associated protein
CH92_15590	COG1968	undecaprenyl-diphosphatase activity
CH92_15600	COG2827	Endonuclease containing a URI domain
CH92_15605	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CH92_15610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH92_15615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CH92_15625	COG0583	DNA-binding transcription factor activity
CH92_15650	COG3530	Putative quorum-sensing-regulated virulence factor
CH92_15665	COG2814	Major facilitator Superfamily
CH92_15685	COG0784	Response regulator, receiver
CH92_15690	COG3920	Histidine kinase
CH92_15695	COG0490	domain, Protein
CH92_15695	COG0471	metal ion transport
CH92_15725	COG2733	membrane
CH92_15740	COG2610	gluconate transmembrane transporter activity
CH92_15745	COG0625	glutathione transferase activity
CH92_15780	COG1335	isochorismatase
CH92_15790	COG0730	response to heat
CH92_15795	COG1234	tRNA 3'-trailer cleavage
CH92_15805	COG0655	NAD(P)H dehydrogenase (quinone) activity
CH92_15815	COG1309	transcriptional regulator
CH92_15835	COG1643	Atp-dependent helicase
CH92_15845	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_15850	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_15855	COG2030	dehydratase
CH92_15885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CH92_15890	COG1201	RNA secondary structure unwinding
CH92_15900	COG4221	oxidoreductase activity
CH92_15905	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CH92_15915	COG4935	Belongs to the peptidase S8 family
CH92_15915	COG1404	Belongs to the peptidase S8 family
CH92_15935	COG0513	Belongs to the DEAD box helicase family
CH92_15965	COG0443	Heat shock 70 kDa protein
CH92_15970	COG2271	Major facilitator Superfamily
CH92_15975	COG3622	Belongs to the hyi family
CH92_15980	COG2084	Dehydrogenase
CH92_16000	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH92_16010	COG3639	organic phosphonate transmembrane transporter activity
CH92_16075	COG0402	S-adenosylhomocysteine deaminase activity
CH92_16080	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH92_16090	COG1121	(ABC) transporter
CH92_16095	COG1802	Transcriptional regulator
CH92_16100	COG2252	PERMEase
CH92_16125	COG4266	Belongs to the allantoicase family
CH92_16130	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CH92_16140	COG2233	PERMEase
CH92_16145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH92_16145	COG4651	solute:proton antiporter activity
CH92_16150	COG2233	PERMEase
CH92_16160	COG0840	transmembrane signaling receptor activity
CH92_16165	COG3706	GGDEF domain
CH92_16175	COG1309	transcriptional regulator
CH92_16200	COG1704	LemA family
CH92_16230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH92_16235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH92_16245	COG0459	protein refolding
CH92_16250	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CH92_16260	COG3030	protein affecting phage T7 exclusion by the F plasmid
CH92_16270	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_16280	COG3695	enzyme binding
CH92_16290	COG0668	transmembrane transport
CH92_16295	COG1666	GTP binding
CH92_16310	COG4191	Histidine kinase
CH92_16315	COG2096	Adenosyltransferase
CH92_16345	COG0494	nUDIX hydrolase
CH92_16355	COG0653	protein targeting
CH92_16400	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CH92_16420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CH92_16425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH92_16435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CH92_16440	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CH92_16450	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CH92_16455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CH92_16475	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CH92_16495	COG1408	metallophosphoesterase
CH92_16505	COG0583	DNA-binding transcription factor activity
CH92_16510	COG2814	Major facilitator Superfamily
CH92_16515	COG0656	L-ascorbic acid biosynthetic process
CH92_16530	COG1196	nuclear chromosome segregation
CH92_16555	COG0165	Argininosuccinate lyase
CH92_16565	COG0583	DNA-binding transcription factor activity
CH92_16580	COG0288	reversible hydration of carbon dioxide
CH92_16585	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CH92_16590	COG1877	trehalose-phosphatase activity
CH92_16600	COG0456	acetyltransferase
CH92_16610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CH92_16660	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CH92_16670	COG1183	phosphatidylcholine synthase activity
CH92_16675	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CH92_16685	COG0028	Belongs to the TPP enzyme family
CH92_16695	COG3098	single-species biofilm formation
CH92_16705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH92_16715	COG2226	methyltransferase
CH92_16760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CH92_16775	COG2264	protein methyltransferase activity
CH92_16785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH92_16795	COG0138	bifunctional purine biosynthesis protein purh
CH92_16800	COG0151	Belongs to the GarS family
CH92_16805	COG5002	protein histidine kinase activity
CH92_16805	COG2205	protein histidine kinase activity
CH92_16805	COG0784	Response regulator, receiver
CH92_16810	COG2124	cytochrome p450
CH92_16825	COG0679	Auxin Efflux Carrier
CH92_16850	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CH92_16855	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH92_16870	COG1181	Belongs to the D-alanine--D-alanine ligase family
CH92_16875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH92_16880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CH92_16885	COG0772	Belongs to the SEDS family
CH92_16890	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CH92_16895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH92_16900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH92_16905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH92_16920	COG0275	rRNA processing
CH92_16935	COG3107	peptidoglycan biosynthetic process
CH92_16940	COG0792	nuclease activity
CH92_16945	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CH92_16950	COG2823	Periplasmic or secreted lipoprotein
CH92_16955	COG2969	positive regulation of protein catabolic process
CH92_16960	COG0625	glutathione transferase activity
CH92_16965	COG2857	Cytochrome c1
CH92_16970	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CH92_16975	COG0723	plastoquinol--plastocyanin reductase activity
CH92_16980	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CH92_16985	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CH92_16990	COG0667	Aldo Keto reductase
CH92_17005	COG0237	dephospho-CoA kinase activity
CH92_17010	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CH92_17025	COG4969	Belongs to the N-Me-Phe pilin family
CH92_17060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH92_17065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CH92_17075	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CH92_17080	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CH92_17105	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH92_17110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH92_17115	COG1127	ABC transporter
CH92_17125	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH92_17135	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH92_17140	COG1137	ATPase activity
CH92_17145	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH92_17160	COG1660	Displays ATPase and GTPase activities
CH92_17170	COG0312	modulator of DNA gyrase
CH92_17180	COG0312	modulator of DNA gyrase
CH92_17185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH92_17195	COG1530	ribonuclease E activity
CH92_17200	COG0424	maF-like protein
CH92_17210	COG1792	Involved in formation and maintenance of cell shape
CH92_17215	COG1077	Cell shape determining protein MreB Mrl
CH92_17220	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CH92_17230	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CH92_17235	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH92_17240	COG0530	calcium, potassium:sodium antiporter activity
CH92_17260	COG0739	heme binding
CH92_17275	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CH92_17310	COG4774	siderophore transport
CH92_17315	COG3128	pkhd-type hydroxylase
CH92_17325	COG0019	diaminopimelate decarboxylase activity
CH92_17330	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CH92_17335	COG0564	pseudouridine synthase activity
CH92_17345	COG0028	Belongs to the TPP enzyme family
CH92_17365	COG3212	peptidase
CH92_17370	COG0745	RESPONSE REGULATOR receiver
CH92_17375	COG2205	protein histidine kinase activity
CH92_17400	COG0420	3'-5' exonuclease activity
CH92_17425	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CH92_17450	COG1607	acyl-coa hydrolase
CH92_17455	COG2824	Alkylphosphonate utilization operon protein PhnA
CH92_17460	COG4993	Dehydrogenase
CH92_17465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH92_17465	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH92_17465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH92_17470	COG1105	Belongs to the carbohydrate kinase PfkB family
CH92_17475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH92_17475	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH92_17480	COG1609	Transcriptional regulator
CH92_17490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH92_17520	COG0534	Mate efflux family protein
CH92_17555	COG0346	lactoylglutathione lyase activity
CH92_17630	COG1253	flavin adenine dinucleotide binding
CH92_17660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH92_17680	COG1739	Uncharacterized protein family UPF0029
CH92_17685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CH92_17690	COG0583	DNA-binding transcription factor activity
CH92_17700	COG2814	Major facilitator Superfamily
CH92_17705	COG1309	transcriptional regulator
CH92_17735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH92_17740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH92_17745	COG1538	Outer membrane efflux protein
CH92_17755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH92_17755	COG2169	Transcriptional regulator
CH92_17765	COG0084	hydrolase, TatD family'
CH92_17780	COG0840	transmembrane signaling receptor activity
CH92_17790	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH92_17795	COG1515	deoxyribonuclease V activity
CH92_17800	COG4977	sequence-specific DNA binding
CH92_17805	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH92_17810	COG0180	Tryptophanyl-tRNA synthetase
CH92_17840	COG1252	NADH dehydrogenase
CH92_17900	COG0745	RESPONSE REGULATOR receiver
CH92_17900	COG3706	GGDEF domain
CH92_17910	COG1032	radical SAM domain protein
CH92_17940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH92_17955	COG0305	Participates in initiation and elongation during chromosome replication
CH92_17960	COG0359	binds to the 23S rRNA
CH92_17970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH92_17975	COG0360	Binds together with S18 to 16S ribosomal RNA
CH92_17985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH92_17990	COG0557	exoribonuclease II activity
CH92_18005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CH92_18010	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CH92_18015	COG0330	HflC and HflK could
CH92_18020	COG0330	HflC and HflK could
CH92_18025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH92_18030	COG1923	regulation of RNA biosynthetic process
CH92_18035	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CH92_18040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CH92_18045	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH92_18050	COG0802	atpase or kinase
CH92_18055	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH92_18055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH92_18075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH92_18080	COG1012	belongs to the aldehyde dehydrogenase family
CH92_18085	COG0531	amino acid
CH92_18090	COG4303	Ethanolamine ammonia lyase large subunit
CH92_18095	COG4302	ethanolamine ammonia-lyase activity
CH92_18110	COG3228	Belongs to the MtfA family
CH92_18130	COG3384	dioxygenase
CH92_18135	COG1234	tRNA 3'-trailer cleavage
CH92_18140	COG0583	DNA-binding transcription factor activity
CH92_18145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH92_18150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH92_18155	COG2828	Protein conserved in bacteria
CH92_18170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH92_18180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH92_18185	COG1120	ATPase activity
CH92_18190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_18210	COG0784	Response regulator, receiver
CH92_18210	COG4191	Histidine kinase
CH92_18215	COG3546	catalase activity
CH92_18225	COG4067	protein conserved in archaea
CH92_18225	COG0189	ligase activity
CH92_18240	COG1230	cation diffusion facilitator family transporter
CH92_18250	COG0730	response to heat
CH92_18255	COG1722	exodeoxyribonuclease VII activity
CH92_18260	COG0142	geranyltranstransferase activity
CH92_18265	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CH92_18275	COG4206	TonB-dependent receptor
CH92_18280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH92_18290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CH92_18295	COG3577	Aspartyl protease
CH92_18305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH92_18310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CH92_18315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CH92_18335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH92_18335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH92_18350	COG2264	protein methyltransferase activity
CH92_18360	COG3118	belongs to the thioredoxin family
CH92_18370	COG1946	Acyl-CoA thioesterase
CH92_18380	COG0123	including yeast histone deacetylase and acetoin utilization protein
CH92_18400	COG0513	Belongs to the DEAD box helicase family
CH92_18425	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_18435	COG1643	Atp-dependent helicase
CH92_18455	COG1522	sequence-specific DNA binding
CH92_18490	COG0411	ABC transporter
CH92_18510	COG0410	ABC transporter
CH92_18515	COG0411	ABC transporter
CH92_18525	COG0559	Belongs to the binding-protein-dependent transport system permease family
CH92_18530	COG0829	nickel cation binding
CH92_18535	COG0831	urea catabolic process
CH92_18545	COG0832	Belongs to the urease beta subunit family
CH92_18550	COG0804	urea catabolic process
CH92_18555	COG1953	Uracil, thiamine, allantoin
CH92_18570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH92_18580	COG2814	Major facilitator Superfamily
CH92_18585	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CH92_18600	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CH92_18605	COG0830	nickel cation binding
CH92_18610	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH92_18620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH92_18635	COG1960	acyl-CoA dehydrogenase activity
CH92_18640	COG4999	Histidine kinase
CH92_18640	COG3437	response regulator, receiver
CH92_18640	COG2205	protein histidine kinase activity
CH92_18640	COG3850	Histidine kinase
CH92_18650	COG0351	phosphomethylpyrimidine kinase
CH92_18660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CH92_18680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CH92_18685	COG1702	phosphate starvation-inducible protein PhoH
CH92_18690	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CH92_18695	COG4535	Mg2 and Co2 transporter CorC
CH92_18700	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH92_18715	COG0495	leucyl-tRNA aminoacylation
CH92_18735	COG2951	lytic endotransglycosylase activity
CH92_18750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CH92_18755	COG0321	lipoyl(octanoyl) transferase activity
CH92_18760	COG2921	Belongs to the UPF0250 family
CH92_18765	COG1686	Belongs to the peptidase S11 family
CH92_18775	COG2951	lytic endotransglycosylase activity
CH92_18780	COG0772	Belongs to the SEDS family
CH92_18785	COG0768	penicillin binding
CH92_18790	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CH92_18800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CH92_18805	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CH92_18810	COG0586	Pfam SNARE associated Golgi protein
CH92_18820	COG1346	cytolysis
CH92_18840	COG0702	epimerase
CH92_18845	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH92_18855	COG1162	GTPase activity
CH92_18860	COG1360	Flagellar Motor Protein
CH92_18865	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH92_18880	COG0688	phosphatidylethanolamine metabolic process
CH92_18895	COG3830	Belongs to the UPF0237 family
CH92_18895	COG0560	Phosphoserine phosphatase
CH92_18930	COG3150	esterase
CH92_18935	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH92_18945	COG0494	nUDIX hydrolase
CH92_18960	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CH92_18965	COG1538	Outer membrane efflux protein
CH92_18970	COG1519	Transferase
CH92_18985	COG0667	Aldo Keto reductase
CH92_18995	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CH92_18995	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CH92_19010	COG1132	(ABC) transporter
CH92_19035	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CH92_19040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CH92_19055	COG0438	transferase activity, transferring glycosyl groups
CH92_19060	COG2192	nodulation
CH92_19080	COG0438	transferase activity, transferring glycosyl groups
CH92_19085	COG0859	PFAM glycosyl transferase family 9
CH92_19090	COG0859	PFAM glycosyl transferase family 9
CH92_19100	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CH92_19125	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CH92_19130	COG1960	acyl-CoA dehydrogenase activity
CH92_19135	COG1960	acyl-CoA dehydrogenase activity
CH92_19140	COG3706	GGDEF domain
CH92_19145	COG1960	acyl-CoA dehydrogenase activity
CH92_19165	COG1073	alpha beta
CH92_19165	COG2226	methyltransferase
CH92_19170	COG0156	8-amino-7-oxononanoate synthase activity
CH92_19175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CH92_19180	COG1040	competence protein
CH92_19185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH92_19190	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH92_19235	COG1960	acyl-CoA dehydrogenase activity
CH92_19240	COG3263	regulation of cellular component size
CH92_19245	COG3264	Mechanosensitive ion channel
CH92_19245	COG1196	nuclear chromosome segregation
CH92_19250	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CH92_19260	COG3501	Rhs element vgr protein
CH92_19365	COG3706	GGDEF domain
CH92_19365	COG0745	RESPONSE REGULATOR receiver
CH92_19375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH92_19405	COG0330	HflC and HflK could
CH92_19430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH92_19465	COG1595	DNA-templated transcription, initiation
CH92_19470	COG3712	iron ion homeostasis
CH92_19495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH92_19510	COG0513	Belongs to the DEAD box helicase family
CH92_19520	COG1289	transmembrane transporter activity
CH92_19525	COG2081	HI0933 family
CH92_19555	COG2204	response regulator
CH92_19560	COG0191	fructose-bisphosphate aldolase activity
CH92_19575	COG0126	phosphoglycerate kinase activity
CH92_19580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CH92_19585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH92_19590	COG0583	DNA-binding transcription factor activity
CH92_19605	COG2226	methyltransferase
CH92_19610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CH92_19620	COG0842	Transport permease protein
CH92_19625	COG1131	(ABC) transporter
CH92_19630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CH92_19655	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CH92_19660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CH92_19670	COG1538	Outer membrane efflux protein
CH92_19680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH92_19685	COG2353	YceI-like domain
CH92_19690	COG3038	cytochrome b561
CH92_19700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH92_19715	COG2198	Histidine kinase
CH92_19715	COG0643	Histidine kinase
CH92_19755	COG1678	Uncharacterized ACR, COG1678
CH92_19770	COG0540	Belongs to the ATCase OTCase family
CH92_19820	COG1160	GTP binding
CH92_19825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CH92_19830	COG2813	Specifically methylates the guanine in position
CH92_19830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CH92_19840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH92_19845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH92_19860	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CH92_19865	COG2022	thiamine diphosphate biosynthetic process
CH92_19875	COG2363	Small membrane protein
CH92_19880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH92_19895	COG2177	Part of the ABC transporter FtsEX involved in
CH92_19900	COG2884	Cell division ATP-binding protein ftsE
CH92_19905	COG0552	protein localization to endoplasmic reticulum
CH92_19910	COG0612	Peptidase, M16
CH92_19915	COG0612	Peptidase, M16
CH92_19920	COG0742	ribosomal rna small subunit methyltransferase
CH92_19930	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CH92_19935	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH92_19945	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CH92_19955	COG0693	protein deglycase activity
CH92_19960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CH92_19970	COG2207	Transcriptional regulator
CH92_19975	COG2831	hemolysin activation secretion protein
CH92_19990	COG0129	dihydroxy-acid dehydratase activity
CH92_20000	COG2233	PERMEase
CH92_20010	COG2233	PERMEase
CH92_20015	COG0579	oxidoreductase
CH92_20035	COG0584	glycerophosphoryl diester phosphodiesterase
CH92_20040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_20085	COG0704	Plays a role in the regulation of phosphate uptake
CH92_20090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CH92_20095	COG0581	inorganic phosphate transmembrane transporter activity
CH92_20110	COG1607	acyl-coa hydrolase
CH92_20115	COG5001	Diguanylate cyclase
CH92_20115	COG4251	negative regulation of phosphorylation
CH92_20115	COG3706	GGDEF domain
CH92_20115	COG2203	Gaf domain
CH92_20135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH92_20150	COG1283	sodium-dependent phosphate transmembrane transporter activity
CH92_20165	COG3706	GGDEF domain
CH92_20165	COG0745	RESPONSE REGULATOR receiver
CH92_20170	COG0642	Histidine kinase
CH92_20205	COG0700	Nucleoside recognition
CH92_20225	COG2204	response regulator
CH92_20230	COG5002	protein histidine kinase activity
CH92_20240	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH92_20245	COG3706	GGDEF domain
CH92_20245	COG0745	RESPONSE REGULATOR receiver
CH92_20265	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CH92_20270	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CH92_20270	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CH92_20285	COG1178	ABC-type Fe3 transport system permease component
CH92_20300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH92_20305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH92_20310	COG0006	proline dipeptidase activity
CH92_20315	COG3079	Belongs to the UPF0149 family
CH92_20330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH92_20350	COG0604	alcohol dehydrogenase
CH92_20355	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CH92_20370	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CH92_20375	COG4942	peptidase
CH92_20380	COG0793	Belongs to the peptidase S41A family
CH92_20385	COG2861	carbohydrate metabolic process
CH92_20405	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CH92_20420	COG0131	Imidazoleglycerol-phosphate dehydratase
CH92_20435	COG1194	a g-specific adenine glycosylase
CH92_20440	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CH92_20450	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CH92_20455	COG0732	type I restriction modification DNA specificity domain
CH92_20475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_20500	COG0676	glucose-6-phosphate 1-epimerase activity
CH92_20535	COG0583	DNA-binding transcription factor activity
CH92_20545	COG1027	Aspartate ammonia-lyase
CH92_20560	COG1115	amino acid carrier protein
CH92_20565	COG0252	asparaginase activity
CH92_20570	COG2205	protein histidine kinase activity
CH92_20575	COG1218	3'(2'),5'-bisphosphate nucleotidase
CH92_20580	COG0494	nUDIX hydrolase
CH92_20585	COG1011	Hydrolase
CH92_20595	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CH92_20605	COG3383	formate dehydrogenase (NAD+) activity
CH92_20620	COG1910	domain protein
CH92_20635	COG0824	Thioesterase
CH92_20640	COG1454	alcohol dehydrogenase
CH92_20645	COG1960	acyl-CoA dehydrogenase activity
CH92_20650	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH92_20650	COG1024	Enoyl-CoA hydratase
CH92_20660	COG1278	Cold shock
CH92_20665	COG5002	protein histidine kinase activity
CH92_20680	COG0445	tRNA wobble uridine modification
CH92_20690	COG0667	Aldo Keto reductase
CH92_20705	COG0514	ATP-dependent DNA helicase (RecQ)
CH92_20720	COG0778	Nitroreductase
CH92_20750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CH92_20780	COG0463	Glycosyl transferase, family 2
CH92_20790	COG0726	polysaccharide deacetylase
CH92_20820	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH92_20825	COG4067	protein conserved in archaea
CH92_20825	COG0189	ligase activity
CH92_20830	COG0189	ligase activity
CH92_20835	COG2205	protein histidine kinase activity
CH92_20840	COG0745	RESPONSE REGULATOR receiver
CH92_20845	COG2183	response to ionizing radiation
CH92_20855	COG2918	glutathione biosynthetic process
CH92_20875	COG0306	phosphate transporter
CH92_20880	COG1392	Phosphate transport regulator
CH92_20915	COG1764	response to oxidative stress
CH92_20920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CH92_20975	COG0586	Pfam SNARE associated Golgi protein
CH92_20995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH92_21015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH92_21020	COG1127	ABC transporter
CH92_21025	COG3218	ABC-type transport auxiliary lipoprotein component
CH92_21025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH92_21055	COG1091	dTDP-4-dehydrorhamnose reductase activity
CH92_21105	COG1177	transmembrane transport
CH92_21110	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH92_21115	COG3842	ATPase activity
CH92_21135	COG0174	glutamine synthetase
CH92_21140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CH92_21145	COG0174	glutamine synthetase
CH92_21170	COG2957	Belongs to the agmatine deiminase family
CH92_21175	COG3706	GGDEF domain
CH92_21185	COG0745	RESPONSE REGULATOR receiver
CH92_21190	COG5002	protein histidine kinase activity
CH92_21195	COG4565	transcriptional regulatory protein
CH92_21200	COG3706	GGDEF domain
CH92_21200	COG0745	RESPONSE REGULATOR receiver
CH92_21205	COG5002	protein histidine kinase activity
CH92_21210	COG0745	RESPONSE REGULATOR receiver
CH92_21230	COG1012	belongs to the aldehyde dehydrogenase family
CH92_21240	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CH92_21245	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CH92_21270	COG1960	acyl-CoA dehydrogenase activity
CH92_21275	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH92_21275	COG1024	Enoyl-CoA hydratase
CH92_21295	COG1960	acyl-CoA dehydrogenase activity
CH92_21300	COG1309	transcriptional regulator
CH92_21315	COG2188	Transcriptional regulator
CH92_21320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_21325	COG1960	acyl-CoA dehydrogenase activity
CH92_21360	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CH92_21365	COG3835	regulator
CH92_21370	COG0402	S-adenosylhomocysteine deaminase activity
CH92_21405	COG1335	isochorismatase
CH92_21410	COG1309	transcriptional regulator
CH92_21415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH92_21420	COG1335	isochorismatase
CH92_21425	COG0251	oxidation-reduction process
CH92_21430	COG0596	Alpha beta hydrolase
CH92_21435	COG0778	Nitroreductase
CH92_21440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH92_21460	COG1304	FMN binding
CH92_21465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_21490	COG4948	Mandelate Racemase Muconate Lactonizing
CH92_21495	COG1609	Transcriptional regulator
CH92_21500	COG0129	dihydroxy-acid dehydratase activity
CH92_21525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_21540	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH92_21560	COG3052	prosthetic group binding
CH92_21565	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CH92_21575	COG1238	metal cluster binding
CH92_21615	COG3712	iron ion homeostasis
CH92_21620	COG1595	DNA-templated transcription, initiation
CH92_21635	COG0523	cobalamin synthesis protein
CH92_21650	COG4251	negative regulation of phosphorylation
CH92_21655	COG0784	Response regulator, receiver
CH92_21660	COG4191	Histidine kinase
CH92_21660	COG0784	Response regulator, receiver
CH92_21700	COG4774	siderophore transport
CH92_21710	COG1595	DNA-templated transcription, initiation
CH92_21745	COG2826	transposase and inactivated derivatives, IS30 family
CH92_21755	COG2815	serine threonine protein kinase
CH92_21755	COG0515	serine threonine protein kinase
CH92_21780	COG1061	Type III restriction enzyme res subunit
CH92_21820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CH92_21825	COG1349	DNA-binding transcription factor activity
CH92_21830	COG0840	transmembrane signaling receptor activity
CH92_21835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CH92_21840	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CH92_21845	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CH92_21850	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CH92_21855	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CH92_21860	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CH92_21865	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CH92_21880	COG3312	ion transport
CH92_21885	COG1475	DNA binding
CH92_21890	COG1192	Involved in chromosome partitioning
CH92_21895	COG0357	Ribosomal RNA small subunit methyltransferase G
CH92_21900	COG0445	tRNA wobble uridine modification
CH92_21905	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CH92_21910	COG0706	membrane insertase activity
CH92_21915	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CH92_21920	COG0594	ribonuclease P activity
CH92_21925	COG0230	Belongs to the bacterial ribosomal protein bL34 family