locus-tag class description PsyrB_00005 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) PsyrB_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) PsyrB_00015 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) PsyrB_00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) PsyrB_00035 ENOG4105ES4 Nitrilase PsyrB_00050 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase PsyrB_00055 ENOG4105C38 Glycyl-tRNA synthetase beta subunit PsyrB_00060 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit PsyrB_00065 ENOG4108R3E Dna-3-methyladenine glycosylase i PsyrB_00075 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit PsyrB_00080 ENOG4105C1A potassium transporter peripheral membrane PsyrB_00085 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B PsyrB_00090 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) PsyrB_00095 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) PsyrB_00105 ENOG4105C79 DNA protecting protein DprA PsyrB_00110 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) PsyrB_00115 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein PsyrB_00120 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) PsyrB_00125 ENOG4105E2X shikimate dehydrogenase PsyrB_00145 ENOG4105CBG Sulfatase PsyrB_00150 ENOG4108PZW LysR family Transcriptional regulator PsyrB_00185 ENOG41082A2 Alpha beta hydrolase PsyrB_00195 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) PsyrB_00200 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) PsyrB_00215 ENOG4105WKW Pfam:DUF1458 PsyrB_00225 ENOG4105DEN Luciferase family PsyrB_00230 ENOG4108Z9K Osmotically inducible protein PsyrB_00255 ENOG4108Z0R Transferase PsyrB_00260 ENOG4105DGW oligopeptidase A PsyrB_00265 ENOG4105VKU nucleicacid-binding protein PsyrB_00280 ENOG4107SJW iron permease, FTR1 PsyrB_00285 ENOG410829K Lysine exporter protein (Lyse ygga) PsyrB_00295 ENOG4105C5H ABC transporter PsyrB_00315 ENOG4105PBF Anti-RNA polymerase sigma 70 factor PsyrB_00335 ENOG41076E6 Uroporphyrinogen-III Synthase PsyrB_00340 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) PsyrB_00345 ENOG4108NEV two component transcriptional regulator, LytTR family PsyrB_00355 ENOG4105CH7 arginosuccinase PsyrB_00370 ENOG4107RAN Peptidase, M16 PsyrB_00375 ENOG4105EAM Na Pi-cotransporter PsyrB_00380 ENOG4108NVR Methyl-accepting chemotaxis PsyrB_00385 ENOG4105ETT transcriptional Regulator, LysR family PsyrB_00390 ENOG4107QI1 Mate efflux family protein PsyrB_00395 ENOG4105BZU Histidine kinase PsyrB_00400 ENOG4105C4R Atp-dependent dna helicase PsyrB_00405 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) PsyrB_00415 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_00435 ENOG4108IJ6 ABC transporter PsyrB_00440 ENOG4105ECW sulfate abc transporter PsyrB_00445 ENOG4108I5D sulfate abc transporter PsyrB_00450 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein PsyrB_00460 ENOG4105BZU Histidine kinase PsyrB_00470 ENOG4105BZU Histidine kinase PsyrB_00475 ENOG4108PYU two-component system response regulator PsyrB_00480 ENOG4108JPW Aminotransferase PsyrB_00490 ENOG4105C26 Dehydrogenase PsyrB_00560 ENOG4105IE8 Alpha-ketoglutarate permease PsyrB_00590 ENOG4105CIR epoxide hydrolase PsyrB_00605 ENOG4105N14 lysine exporter protein LysE YggA PsyrB_00615 ENOG4105X1Z Methyltransferase type 12 PsyrB_00630 ENOG4105DYS nad(p)h dehydrogenase (quinone) PsyrB_00640 ENOG4105DDI hemolysin-type calcium-binding region PsyrB_00650 ENOG4105KAF membrAne PsyrB_00675 ENOG4108UYU AsnC family transcriptional regulator PsyrB_00680 ENOG4105C3J Cysteine desulfurase PsyrB_00685 ENOG4105WQ5 TonB family PsyrB_00695 ENOG4105SG9 biopolymer transport protein, ExbD PsyrB_00700 ENOG4105D05 Receptor PsyrB_00705 ENOG4105E43 Extracellular solute-binding protein, family 5 PsyrB_00710 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component PsyrB_00715 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component PsyrB_00720 ENOG4108JQ5 ABC transporter PsyrB_00730 ENOG4108RYR transcriptional regulator AsnC family PsyrB_00740 ENOG4108JPW Aminotransferase PsyrB_00745 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase PsyrB_00750 ENOG4105C26 Dehydrogenase PsyrB_00755 ENOG4105CWC Acetylornithine deacetylase PsyrB_00780 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component PsyrB_00790 ENOG4105DEF Extracellular solute-binding protein, family 5 PsyrB_00795 ENOG4105CJP fad dependent oxidoreductase PsyrB_00820 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase PsyrB_00825 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) PsyrB_00830 ENOG4105VEJ Heat shock protein PsyrB_00835 ENOG4105BZU Histidine kinase PsyrB_00840 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) PsyrB_00845 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) PsyrB_00850 ENOG4105CK2 sodium dicarboxylate symporter PsyrB_00865 ENOG4107T0K Adenylate cyclase PsyrB_00870 ENOG4105NXH GreA GreB family elongation factor PsyrB_00885 ENOG4105XQ6 frataxin-like protein PsyrB_00895 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) PsyrB_00900 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) PsyrB_00910 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) PsyrB_00925 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme PsyrB_00930 ENOG4105BZU Histidine kinase PsyrB_00935 ENOG4108YZA Nitrogen regulatory protein pii PsyrB_00940 ENOG4105W0Z cytoplasmic protein PsyrB_00950 ENOG4105CF7 AraC family transcriptional regulator PsyrB_00955 ENOG4105EMU Dehydrogenase PsyrB_00990 ENOG4105DQ6 Transposase PsyrB_01000 ENOG4105C0P Mg chelatase subunit ChlI PsyrB_01025 ENOG4108ZXE PsyrB_01050 ENOG4105C0P Mg chelatase subunit ChlI PsyrB_01070 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) PsyrB_01080 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin PsyrB_01085 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) PsyrB_01095 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) PsyrB_01100 ENOG4105ENA helicase PsyrB_01160 ENOG4107S73 homocitrate synthase PsyrB_01170 ENOG4105E5H Transposase PsyrB_01220 ENOG4105C0P Mg chelatase subunit ChlI PsyrB_01225 ENOG4105D4T Citrate transporter PsyrB_01240 ENOG4105CB5 ATP-dependent DNA helicase recG PsyrB_01250 ENOG4105YHG TonB family PsyrB_01255 ENOG4108ZZF transport protein (ExbD) PsyrB_01265 ENOG4108535 NAD dependent epimerase/dehydratase family PsyrB_01275 ENOG4105KME endoribonuclease L-psp PsyrB_01280 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) PsyrB_01285 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) PsyrB_01290 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) PsyrB_01295 ENOG4105DSJ YicC domain protein PsyrB_01300 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) PsyrB_01310 ENOG4105CGK Exodeoxyribonuclease III PsyrB_01315 ENOG4107QP2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) PsyrB_01325 ENOG4105DQ6 Transposase PsyrB_01335 ENOG4105FAV ABC, transporter PsyrB_01340 ENOG4105FDK ABC transporter PsyrB_01345 ENOG4105MYN Zinc uptake regulation protein PsyrB_01350 ENOG4105NXV High-affinity zinc uptake system protein PsyrB_01365 ENOG4105C2M dna polymerase I PsyrB_01375 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) PsyrB_01380 ENOG4108Z33 Thiol disulfide Interchange Protein PsyrB_01390 ENOG4105BZU Histidine kinase PsyrB_01395 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase PsyrB_01400 ENOG4105ES5 Histidine kinase PsyrB_01405 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_01425 ENOG4108ZGU inhibitor of vertebrate lysozyme PsyrB_01430 ENOG4105E0F Histidine kinase PsyrB_01435 ENOG4105DPZ Two component transcriptional regulator (Winged helix family PsyrB_01440 ENOG4105BZM domain protein PsyrB_01445 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) PsyrB_01450 ENOG4105D9M gamma-glutamylcysteine synthetase PsyrB_01455 ENOG4107QZM n-acetylglutamate synthase PsyrB_01470 ENOG4108XM1 transcriptional regulator AsnC family PsyrB_01480 ENOG4107QHF type ii secretion system protein e PsyrB_01500 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) PsyrB_01505 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) PsyrB_01510 ENOG4107QVT Binding-protein-dependent transport systems, inner membrane component PsyrB_01515 ENOG4107QKW extracellular solute-binding protein family 1 PsyrB_01530 ENOG4105CYC Transferase PsyrB_01535 ENOG4105MPD Cytochrome PsyrB_01545 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) PsyrB_01555 ENOG4105MWK D-amino acid dehydrogenase, small subunit PsyrB_01560 ENOG4105EW9 transcriptional regulator AsnC family PsyrB_01570 ENOG4105CJP fad dependent oxidoreductase PsyrB_01580 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family PsyrB_01585 ENOG4107RZC phospholipase d PsyrB_01595 ENOG4105C26 Dehydrogenase PsyrB_01605 ENOG4105W0E 50S ribosomal protein L33 PsyrB_01610 ENOG4105KDC 50s ribosomal protein l28 PsyrB_01615 ENOG4105DEF Extracellular solute-binding protein, family 5 PsyrB_01620 ENOG4105W5Q DNA repair protein (RadC PsyrB_01625 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase PsyrB_01630 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) PsyrB_01635 ENOG4107QKV phosphomannomutase PsyrB_01640 ENOG4105CAS nag kinase PsyrB_01650 ENOG4105DQ6 Transposase PsyrB_01655 ENOG4105NXV High-affinity zinc uptake system protein PsyrB_01660 ENOG4105MYN Zinc uptake regulation protein PsyrB_01665 ENOG4105FDK ABC transporter PsyrB_01670 ENOG4105FAV ABC, transporter PsyrB_01685 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) PsyrB_01690 ENOG4108UMI ABC transporter, permease PsyrB_01695 ENOG4105D01 (LipO)protein PsyrB_01705 ENOG4105FT1 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) PsyrB_01715 ENOG4105CHH sulfate transporter PsyrB_01720 ENOG4107B2H carbonic anhydrase PsyrB_01730 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain PsyrB_01735 ENOG4105KHU inner membrane protein YohD PsyrB_01740 ENOG4105D52 delta-aminolevulinic acid dehydratase PsyrB_01745 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) PsyrB_01750 ENOG4105C9X ppx gppa phosphatase PsyrB_01755 ENOG4105DQ6 Transposase PsyrB_01765 ENOG4105CDA abc transporter atp-binding protein PsyrB_01770 ENOG4105E5Q amino acid AbC transporter PsyrB_01775 ENOG4105DRP amino acid AbC transporter PsyrB_01780 ENOG4108HW3 (ABC) transporter PsyrB_01785 ENOG41073TP transcriptional regulator PsyrB_01790 ENOG4105K63 Thioredoxin PsyrB_01805 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) PsyrB_01820 ENOG4105CXY transporter PsyrB_01845 ENOG4108MA7 Inherit from COG: YD repeat protein PsyrB_01880 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase PsyrB_01890 ENOG4105W8B Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) PsyrB_01900 ENOG4105E07 UPF0149 protein PsyrB_01905 ENOG4107RAQ aminopeptidase PsyrB_01910 ENOG4105D0A hydroxylase PsyrB_01915 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family PsyrB_01920 ENOG4108ZX5 transcriptional regulator PsyrB_01925 ENOG4105DPW Major facilitator superfamily MFS_1 PsyrB_01935 ENOG4108JU7 Transcriptional regulator PsyrB_01940 ENOG4105D01 (LipO)protein PsyrB_01950 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) PsyrB_01970 ENOG4108Z6K Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity) PsyrB_01995 ENOG4108X1T PAAR repeat-containing protein PsyrB_02005 ENOG4105E2B Taurine dioxygenase PsyrB_02015 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component PsyrB_02045 ENOG4105C1P efflux transporter, rnd family, mfp subunit PsyrB_02055 ENOG4105BZS acriflavin resistance protein PsyrB_02070 ENOG4108UMI ABC transporter, permease PsyrB_02075 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) PsyrB_02080 ENOG4105D01 (LipO)protein PsyrB_02095 ENOG4107T8P acyl-Coa dehydrogenase PsyrB_02100 ENOG4107T8P acyl-Coa dehydrogenase PsyrB_02110 ENOG4105CDA abc transporter atp-binding protein PsyrB_02115 ENOG4105E5Q amino acid AbC transporter PsyrB_02120 ENOG4105EAB amino acid AbC transporter PsyrB_02125 ENOG4105K6H D-cysteine desulfhydrase PsyrB_02130 ENOG4105D7W serine acetyltransferase PsyrB_02140 ENOG4105WH9 RNA polymerase PsyrB_02150 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) PsyrB_02155 ENOG41090B9 response to stress PsyrB_02160 ENOG4105CZE histidine utilization repressor PsyrB_02165 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) PsyrB_02170 ENOG4105QNF Outer membrane lipoprotein PsyrB_02180 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 PsyrB_02200 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) PsyrB_02205 ENOG4108HGY Proline imino-peptidase PsyrB_02210 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) PsyrB_02215 ENOG4105DJ9 glucan biosynthesis protein PsyrB_02220 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) PsyrB_02235 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_02240 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_02255 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) PsyrB_02260 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) PsyrB_02265 ENOG4105KPZ phosphoribosyl-atp pyrophosphatase PsyrB_02270 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase PsyrB_02275 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) PsyrB_02285 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) PsyrB_02305 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) PsyrB_02310 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) PsyrB_02320 ENOG4105C75 arginyL-tRNA synthetase PsyrB_02325 ENOG4105C25 Primosomal protein n' PsyrB_02330 ENOG4105VFB Binds the 23S rRNA (By similarity) PsyrB_02340 ENOG4105C6K Malic enzyme PsyrB_02345 ENOG4108JQC penicillin-binding protein 1A PsyrB_02370 ENOG4105E4G Type IV pilus PsyrB_02375 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) PsyrB_02380 ENOG4105D49 3-dehydroquinate synthase PsyrB_02390 ENOG4105CBC glutamate synthase PsyrB_02395 ENOG4105BZ8 glutamate synthase PsyrB_02405 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) PsyrB_02410 ENOG4107R3N Filamentation induced by cAMP protein fic PsyrB_02435 ENOG4105D94 Major Facilitator Superfamily PsyrB_02440 ENOG4106NZI LysR family Transcriptional regulator PsyrB_02445 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) PsyrB_02450 ENOG4105C2D reductase PsyrB_02460 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) PsyrB_02505 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) PsyrB_02520 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) PsyrB_02535 ENOG4107SKI cobyrinic Acid a,c-diamide synthase PsyrB_02550 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase PsyrB_02555 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) PsyrB_02570 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase PsyrB_02575 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase PsyrB_02590 ENOG4108K70 Transcriptional regulator PsyrB_02595 ENOG4108UT2 hemolysin iii PsyrB_02600 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) PsyrB_02615 ENOG4105DS1 cytochrome b561 PsyrB_02620 ENOG4108YYC ycei family PsyrB_02625 ENOG4105C1J atp-dependent rna helicase PsyrB_02630 ENOG4105SYT Methylenetetrahydrofolate reductase PsyrB_02635 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) PsyrB_02645 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) PsyrB_02650 ENOG4105C6Z Gluconate PsyrB_02655 ENOG4105FB2 class II Aldolase PsyrB_02660 ENOG4105G63 Type III effector Hrp-dependent PsyrB_02665 ENOG4105ZXK Dehydrogenase PsyrB_02675 ENOG4105CHM Aminotransferase PsyrB_02680 ENOG4105C01 Dihydroxy-acid dehydratase PsyrB_02690 ENOG4105CSA Coproporphyrinogen iii oxidase PsyrB_02695 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) PsyrB_02700 ENOG4105DWV Homoserine O-trans-acetylase PsyrB_02705 ENOG4105DWV Homoserine O-trans-acetylase PsyrB_02710 ENOG4108VIA integral membrane protein PsyrB_02715 ENOG4105II7 pyrroline-5-carboxylate reductase PsyrB_02720 ENOG4105DFA alanine racemase domain protein PsyrB_02725 ENOG4105CZX twitching motility protein PsyrB_02730 ENOG4105K4H Nlp p60 protein PsyrB_02740 ENOG4105CD3 dihydroorotase PsyrB_02745 ENOG4105CXT aspartate transcarbamylase PsyrB_02750 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) PsyrB_02755 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) PsyrB_02760 ENOG4108UJU UPF0301 protein PsyrB_02770 ENOG4105D7Z glutathione synthase PsyrB_02775 ENOG4108UNF response regulator PsyrB_02780 ENOG4105M3Z response regulator PsyrB_02785 ENOG4108ZGA chew protein PsyrB_02790 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_02795 ENOG4105CBS Chea signal transduction histidine kinase PsyrB_02805 ENOG4105CNG UPF0061 protein PsyrB_02810 ENOG4105DRR Transcriptional regulator, GntR family PsyrB_02815 ENOG4105C5A transporter PsyrB_02820 ENOG4105E7W lamb ycsf family protein PsyrB_02825 ENOG4105CFM UPF0317 protein PsyrB_02830 ENOG4107R7A Allophanate hydrolase subunit 2 PsyrB_02835 ENOG4108JIK carboxylase PsyrB_02840 ENOG4105EGS Mechanosensitive ion channel PsyrB_02845 ENOG4105C3N Participates in control of cell volume in low-osmolarity conditions (By similarity) PsyrB_02860 ENOG4105CSU acyl-Coa dehydrogenase PsyrB_02865 ENOG4105C26 Dehydrogenase PsyrB_02870 ENOG4105CK7 Sodium proline symporter PsyrB_02880 ENOG4105BZU Histidine kinase PsyrB_02885 ENOG4108VKG metal-dependent hydrolase PsyrB_02895 ENOG4107YB6 acetyltransferase, (GNAT) family PsyrB_02905 ENOG4105EM2 membrane PsyrB_02910 ENOG4105CBX hi0933 family PsyrB_02915 ENOG4105C1J atp-dependent rna helicase PsyrB_02920 ENOG4107QSN dihydrolipoamide acetyltransferase PsyrB_02925 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) PsyrB_02930 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) PsyrB_02935 ENOG4105XA0 heptosyltransferase ii PsyrB_02940 ENOG4105D16 lipopolysaccharide heptosyltransferase i PsyrB_02945 ENOG4107RJ7 Glycosyl transferase (Group 1 PsyrB_02950 ENOG4107543 (lipo)polysaccharide PsyrB_02980 ENOG4105E2K Glycosyl transferase (Group 1 PsyrB_03015 ENOG4105BZ1 (ABC) transporter PsyrB_03020 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) PsyrB_03030 ENOG4107SET aldo keto reductase PsyrB_03035 ENOG41087SS fad dependent oxidoreductase PsyrB_03040 ENOG410814C multidrug resistance protein PsyrB_03045 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase PsyrB_03050 ENOG4105DFG type I secretion outer membrane protein PsyrB_03055 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) PsyrB_03070 ENOG41087AY ADP-Ribose pyrophosphatase PsyrB_03090 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) PsyrB_03095 ENOG4105IPS esterase PsyrB_03100 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) PsyrB_03115 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) PsyrB_03130 ENOG4105EAC phosphoserine phosphatase PsyrB_03140 ENOG4105DJ4 phosphatidylserine decarboxylase PsyrB_03150 ENOG4107RD7 Flagellar Motor Protein, MotA PsyrB_03155 ENOG4105ER2 Ompa motb domain protein PsyrB_03160 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) PsyrB_03165 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) PsyrB_03170 ENOG4105EN6 Membrane PsyrB_03175 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) PsyrB_03180 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) PsyrB_03185 ENOG4105K8N protein family UPF0079, ATPase PsyrB_03190 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase PsyrB_03195 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) PsyrB_03200 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) PsyrB_03205 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) PsyrB_03210 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) PsyrB_03215 ENOG4107QJR hflk protein PsyrB_03220 ENOG4105EPW hflc protein PsyrB_03225 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) PsyrB_03230 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis PsyrB_03235 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_03250 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) PsyrB_03255 ENOG4105C2N RNA methyltransferase TrmH family group 3 PsyrB_03265 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) PsyrB_03280 ENOG4105K9Q Binds to the 23S rRNA (By similarity) PsyrB_03285 ENOG4105CDU Replicative dna helicase PsyrB_03295 ENOG4105CCT upf0313 protein PsyrB_03305 ENOG4105NPQ Pfam:DUF403 PsyrB_03320 ENOG4107RA1 nh(3)-dependent nad( ) synthetase PsyrB_03325 ENOG4107RH7 Nicotinate phosphoribosyltransferase PsyrB_03330 ENOG4105ETT transcriptional Regulator, LysR family PsyrB_03340 ENOG4105C32 Amino acid ABC transporter (Permease) PsyrB_03345 ENOG4105CF8 branched-chain amino acid ABC transporter, permease PsyrB_03350 ENOG4105C0Z ABC transporter PsyrB_03355 ENOG4108IV0 ABC, transporter PsyrB_03360 ENOG4105EMU Dehydrogenase PsyrB_03370 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) PsyrB_03375 ENOG4105CTB Polyprenyl synthetase PsyrB_03380 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) PsyrB_03395 ENOG4105CYM Glutathione S-transferase PsyrB_03400 ENOG4105MFV ABC-2 type transporter PsyrB_03420 ENOG4107VXZ Hydrolase PsyrB_03465 ENOG4108XTP Transcriptional regulator PsyrB_03470 ENOG4105F0N pyrophosphate phospho-hydrolase PsyrB_03475 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) PsyrB_03480 ENOG4105DQR SNARE associated Golgi PsyrB_03485 ENOG4107FQ9 ethanolamine ammonia-lyase PsyrB_03490 ENOG4105CPD ethanolamine ammonia-lyase PsyrB_03495 ENOG4105C26 Dehydrogenase PsyrB_03500 ENOG4105DFU Cell wall formation (By similarity) PsyrB_03505 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase PsyrB_03515 ENOG4105K4T epimerase PsyrB_03535 ENOG41067MG lrgb family PsyrB_03555 ENOG4106371 Methyltransferase PsyrB_03570 ENOG4105CHR reductase PsyrB_03575 ENOG4105CHU acetyl-coa acetyltransferase PsyrB_03590 ENOG4105DHU Bile acid PsyrB_03595 ENOG4105R1U AraC Family Transcriptional Regulator PsyrB_03605 ENOG4108Z6Z Transcriptional regulator PsyrB_03610 ENOG4105C59 p-type ATPase PsyrB_03630 ENOG4105E5M Multidrug resistance protein D PsyrB_03640 ENOG4105EJC lysr family transcriptional regulator PsyrB_03650 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) PsyrB_03665 ENOG4105E0A ABC, transporter PsyrB_03670 ENOG4108IHU transport system permease protein PsyrB_03675 ENOG4105DQ5 transport system permease protein PsyrB_03680 ENOG4108HUF Transporter PsyrB_03690 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) PsyrB_03695 ENOG4105CHR reductase PsyrB_03705 ENOG4105UIB (ABC) transporter PsyrB_03710 ENOG4108JQ9 ABC transporter PsyrB_03720 ENOG4108R86 Transcriptional regulator PsyrB_03725 ENOG4105C2W permease PsyrB_03730 ENOG4105EVZ LysR family transcriptional regulator PsyrB_03740 ENOG4105C26 Dehydrogenase PsyrB_03775 ENOG4105DSY exodeoxyribonuclease V, gamma PsyrB_03780 ENOG4107QKA exodeoxyribonuclease V beta PsyrB_03785 ENOG4107QYX exodeoxyribonuclease v alpha PsyrB_03810 ENOG4105C26 Dehydrogenase PsyrB_03815 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase PsyrB_03835 ENOG4105D5T phosphonate abc transporter PsyrB_03840 ENOG4107T9Q phosphonate abc transporter PsyrB_03845 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) PsyrB_03850 ENOG4105CR7 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity) PsyrB_03860 ENOG4105EAH synthase PsyrB_03865 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) PsyrB_03870 ENOG4105K46 50S ribosomal protein l27 PsyrB_03875 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control PsyrB_03880 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) PsyrB_03885 ENOG4108RH0 Crea protein PsyrB_03895 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) PsyrB_03900 ENOG4105CJR Integral membrane protein (MviN PsyrB_03905 ENOG4105DTN riboflavin biosynthesis protein ribF PsyrB_03910 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) PsyrB_03915 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) PsyrB_03920 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase PsyrB_03925 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) PsyrB_03935 ENOG4105X0D Fimbrial protein PsyrB_03965 ENOG4108DN8 FAD dependent oxidoreductase PsyrB_03970 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_03975 ENOG4107TUY Histidine kinase PsyrB_03985 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane PsyrB_03990 ENOG4105C34 Pseudouridine synthase PsyrB_03995 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase PsyrB_04000 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit PsyrB_04030 ENOG4105F32 YngK protein PsyrB_04035 ENOG4105EDQ levansucrase EC 2.4.1.10 PsyrB_04050 ENOG4105DK0 Indole-3-glycerol phosphate synthase PsyrB_04055 ENOG4106NDP Transcriptional regulator PsyrB_04060 ENOG4107R3K hydrolase PsyrB_04080 ENOG4107T3P ABC, transporter PsyrB_04100 ENOG4105R3P Inner membrane protein yagU PsyrB_04105 ENOG4105CN8 Transcriptional regulator PsyrB_04115 ENOG4105H67 Protein of unknown function (DUF421) PsyrB_04125 ENOG4107PP3 Acetylornithine deacetylase PsyrB_04140 ENOG4105CNN ABC, transporter PsyrB_04145 ENOG4105C2J ABC transporter PsyrB_04150 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator PsyrB_04155 ENOG4105ETE Transcriptional regulator (LacI family PsyrB_04175 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) PsyrB_04180 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) PsyrB_04185 ENOG4105BZU Histidine kinase PsyrB_04190 ENOG4108V3W Chemotaxis protein, CheW PsyrB_04195 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_04200 ENOG4105CBS Chea signal transduction histidine kinase PsyrB_04210 ENOG4108VYJ response regulator receiver protein PsyrB_04215 ENOG4108NVR Methyl-accepting chemotaxis PsyrB_04220 ENOG4105CEP NADH dehydrogenase PsyrB_04240 ENOG41067SF Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) PsyrB_04245 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) PsyrB_04260 ENOG4107QHF type ii secretion system protein e PsyrB_04275 ENOG4105RX8 Protein of unknown function (DUF1523) PsyrB_04300 ENOG4105DAX Pfam:DUF2983 PsyrB_04310 ENOG41083B3 HAD-superfamily subfamily IB hydrolase PsyrB_04350 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase PsyrB_04360 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase PsyrB_04370 ENOG4105EYA deoxyribonuclease PsyrB_04375 ENOG4107B7Y DNA-binding transcriptional regulator FruR PsyrB_04380 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) PsyrB_04385 ENOG4105DE4 1-phosphofructokinase PsyrB_04390 ENOG4105DM4 PTS System PsyrB_04395 ENOG4105CHU acetyl-coa acetyltransferase PsyrB_04405 ENOG4107QP8 phosphohexose isomerase PsyrB_04410 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) PsyrB_04415 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) PsyrB_04420 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase PsyrB_04425 ENOG4105DJ0 Poly(A) Polymerase PsyrB_04435 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_04440 ENOG4105BZU Histidine kinase PsyrB_04450 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) PsyrB_04455 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters PsyrB_04465 ENOG4105PW4 Sugar fermentation stimulation protein homolog PsyrB_04475 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) PsyrB_04495 ENOG4105BZ4 penicillin-binding protein PsyrB_04515 ENOG4105C7K acetolactate synthase PsyrB_04520 ENOG4108ZP8 Acetolactate synthase small subunit PsyrB_04525 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase PsyrB_04530 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase PsyrB_04535 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) PsyrB_04540 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) PsyrB_04600 ENOG4105KEG ribosomal-protein-alanine acetyltransferase PsyrB_04610 ENOG41077A9 carbonic anhydrase PsyrB_04620 ENOG4105EST Metal Dependent Phosphohydrolase PsyrB_04625 ENOG4105EXC Acyl-transferase PsyrB_04630 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA PsyrB_04635 ENOG4105KIR Thiol-disulfide oxidoreductase dcc PsyrB_04640 ENOG4105F27 Major Facilitator PsyrB_04645 ENOG4105VE1 Phosphatidylcholine synthase PsyrB_04670 ENOG4107SDU Methyl-accepting chemotaxis PsyrB_04675 ENOG4105DGI Alkaline phosphatase PsyrB_04685 ENOG4105M8F Biopolymer transport protein exbD tolR PsyrB_04710 ENOG4105WCN acetyltransferase PsyrB_04745 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_04755 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase PsyrB_04770 ENOG4105K6V RNA polymerase PsyrB_04785 ENOG4105VGJ Virulence-associated protein PsyrB_04800 ENOG4105CG6 trap dicarboxylate transporter dctm subunit PsyrB_04810 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit PsyrB_04820 ENOG4105E9Z Nad-dependent epimerase dehydratase PsyrB_04825 ENOG41090KI Outer membrane porin PsyrB_04835 ENOG41061TZ Short-chain dehydrogenase reductase Sdr PsyrB_04840 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_04845 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_04855 ENOG4105DMF Dehydrogenase PsyrB_04860 ENOG4105CMU LysR family (Transcriptional regulator PsyrB_04910 ENOG4108DMA Nad-dependent epimerase dehydratase PsyrB_04915 ENOG4105C0K Gdp-mannose 4,6-dehydratase PsyrB_04920 ENOG4105MFV ABC-2 type transporter PsyrB_04925 ENOG4105EY8 ABC transporter PsyrB_04940 ENOG4105FAW cDP-glucose 4,6-dehydratase PsyrB_04960 ENOG4105CKK Glycosyl transferase, family 2 PsyrB_04965 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase PsyrB_04995 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase PsyrB_05000 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) PsyrB_05005 ENOG4105CJT Mannose-1-phosphate guanylyltransferase PsyrB_05010 ENOG4105C3G gtp-binding protein PsyrB_05015 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) PsyrB_05020 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) PsyrB_05025 ENOG4105C5T Phosphoribosyl pyrophosphate synthase PsyrB_05035 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) PsyrB_05040 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) PsyrB_05045 ENOG4105DJQ tetratricopeptide tpr_2 repeat protein PsyrB_05050 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) PsyrB_05055 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) PsyrB_05060 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) PsyrB_05065 ENOG4105D06 uba thif-type nad fad binding protein PsyrB_05070 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) PsyrB_05075 ENOG41061N2 exported protein PsyrB_05090 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase PsyrB_05105 ENOG4105EMU Dehydrogenase PsyrB_05115 ENOG4105CVP deoxyribo-dipyrimidine photolyase PsyrB_05120 ENOG4108XDN Transcriptional regulator PsyrB_05135 ENOG4108QDE fad dependent oxidoreductase PsyrB_05140 ENOG4105ECP epimerase PsyrB_05145 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) PsyrB_05150 ENOG4105C2W permease PsyrB_05155 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) PsyrB_05160 ENOG4108UGV hypoxanthine phosphoribosyltransferase PsyrB_05175 ENOG4105E5Q amino acid AbC transporter PsyrB_05180 ENOG4105EAB amino acid AbC transporter PsyrB_05190 ENOG4105DWT malate dehydrogenase (quinone) PsyrB_05225 ENOG4108RAV Conserved protein PsyrB_05230 ENOG4108K0D peptidase, M48 PsyrB_05240 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) PsyrB_05245 ENOG4105CCF Lysine exporter protein (Lyse ygga) PsyrB_05250 ENOG4105CEY Amp-dependent synthetase and ligase PsyrB_05260 ENOG4105D25 secreted protein PsyrB_05270 ENOG4105CPI Metal Dependent Phosphohydrolase PsyrB_05275 ENOG4105FVZ flavin reductase domain protein, FMN-binding PsyrB_05280 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) PsyrB_05285 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) PsyrB_05290 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) PsyrB_05295 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) PsyrB_05300 ENOG4108R86 Transcriptional regulator PsyrB_05310 ENOG4108JQ9 ABC transporter PsyrB_05325 ENOG4108ZG0 Ompa motb domain protein PsyrB_05330 ENOG4106HNH Acyl-transferase PsyrB_05335 ENOG4105C6K Malic enzyme PsyrB_05340 ENOG4108YZY peptidylprolyl cis-trans isomerase PsyrB_05345 ENOG4108V06 Glutathione peroxidase PsyrB_05365 ENOG4105EXN Sulfate transport protein CysZ PsyrB_05370 ENOG4105C3M thioredoxin reductase PsyrB_05385 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase PsyrB_05390 ENOG4105EUJ GTP cyclohydrolase i PsyrB_05395 ENOG410642E Short chain dehydrogenase PsyrB_05410 ENOG4105QDK Flavodoxin PsyrB_05415 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr PsyrB_05425 ENOG41063JG Transcriptional regulator PsyrB_05440 ENOG410802X bacteriophage n4 adsorption protein b PsyrB_05450 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase PsyrB_05485 ENOG4105GAV receptor PsyrB_05490 ENOG4108S3W Anti-feci sigma factor, fecr PsyrB_05505 ENOG4108Q5Y Membrane PsyrB_05510 ENOG4105C5I Dehydrogenase PsyrB_05515 ENOG4105CR8 Transcriptional regulator PsyrB_05535 ENOG4105Y49 secretion protein, HlyD family PsyrB_05540 ENOG4105E1F short-chain dehydrogenase reductase PsyrB_05560 ENOG4105CJT Mannose-1-phosphate guanylyltransferase PsyrB_05565 ENOG4105ZJ4 Together with AlgI and AlgJ, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate is important for the architecture of biofilms and increases PsyrB_05570 ENOG4108XTA Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate PsyrB_05575 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein PsyrB_05580 ENOG4105FN4 Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond (By similarity) PsyrB_05585 ENOG4105JHR Alginate biosynthesis protein AlgX PsyrB_05590 ENOG4108C0K Bifunctional protein that converts poly(beta-D- mannuronate) to alpha-L-guluronate and that is also part of a periplasmic protein complex that serves as a scaffold that leads the newly formed alginate polymer through the periplasmic space to the outer membrane secretin AlgE PsyrB_05595 ENOG4105Y9T outer membrane protein AlgE PsyrB_05600 ENOG4105XJP alginate biosynthesis protein PsyrB_05605 ENOG4108UIA Alginate biosynthesis protein Alg44 PsyrB_05610 ENOG4105KZJ alginate biosynthesis protein Alg8 PsyrB_05615 ENOG4105C6Y Udp-glucose 6-dehydrogenase PsyrB_05620 ENOG4105D1Q UPF0246 protein PsyrB_05625 ENOG4108ZJ4 polysaccharide deacetylase PsyrB_05630 ENOG4108IAB Phoh family PsyrB_05635 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) PsyrB_05640 ENOG4105M00 molybdopterin converting factor, subunit 1 PsyrB_05645 ENOG4108ZAF Molybdopterin PsyrB_05650 ENOG4105C1J atp-dependent rna helicase PsyrB_05665 ENOG4105EZ7 amino acid ABC transporter PsyrB_05670 ENOG4105DRP amino acid AbC transporter PsyrB_05675 ENOG4105CDA abc transporter atp-binding protein PsyrB_05680 ENOG4105DJ2 Major Facilitator Superfamily PsyrB_05690 ENOG4105KVH Transcriptional regulator PsyrB_05700 ENOG41082IR Excinuclease ABC C subunit domain protein PsyrB_05715 ENOG4106V8H Nucleoid-associated protein PsyrB_05725 ENOG4105EBA Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity) PsyrB_05730 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) PsyrB_05745 ENOG4105MYG DNA polymerase iii, chi subunit PsyrB_05750 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) PsyrB_05755 ENOG4108M8S permease YjgP YjgQ family protein PsyrB_05760 ENOG4108K5H permease YjgP YjgQ family protein PsyrB_05770 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) PsyrB_05775 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor PsyrB_05780 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) PsyrB_05785 ENOG4105BZU Histidine kinase PsyrB_05790 ENOG4108UXN response regulator PsyrB_05795 ENOG4105BZU Histidine kinase PsyrB_05815 ENOG4105WD1 Membrane PsyrB_05820 ENOG4108YNN Heme oxygenase PsyrB_05825 ENOG4107ENK receptor PsyrB_05835 ENOG4105DU6 RNA polymerase PsyrB_05840 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase PsyrB_05845 ENOG4105C01 Dihydroxy-acid dehydratase PsyrB_05855 ENOG4105DPZ Two component transcriptional regulator (Winged helix family PsyrB_05860 ENOG4105E0F Histidine kinase PsyrB_05865 ENOG4108JP0 extracellular solute-binding protein family 1 PsyrB_05870 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component PsyrB_05885 ENOG4105TW1 Carbohydrate-selective porin OprB PsyrB_05890 ENOG4105DSB aldose 1-epimerase PsyrB_05900 ENOG4106KNT transcriptional regulator PsyrB_05905 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase PsyrB_05915 ENOG4108UHU Aldolase PsyrB_05920 ENOG4105VRT cytoplasmic protein PsyrB_05935 ENOG4105GR3 Histidine kinase PsyrB_05965 ENOG4105GQR Chaperone PsyrB_05970 ENOG4105CW0 outer membrane usher protein PsyrB_05975 ENOG4105GQR Chaperone PsyrB_06000 ENOG4107R88 Chemotaxis protein (CheV) PsyrB_06005 ENOG4105RXK Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) PsyrB_06015 ENOG4105E2S oxidase) subunit II PsyrB_06020 ENOG4105BZ9 Cytochrome C oxidase, subunit I PsyrB_06025 ENOG4105CCU oxidase (Subunit III) PsyrB_06030 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) PsyrB_06035 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) PsyrB_06055 ENOG4105CM2 brancheD-chain amino acid aminotransferase PsyrB_06070 ENOG4105F87 Dehydratase PsyrB_06075 ENOG4105WAB arsR family transcriptional regulator PsyrB_06085 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) PsyrB_06105 ENOG4105BZU Histidine kinase PsyrB_06110 ENOG4105C6Z Gluconate PsyrB_06115 ENOG4105BZU Histidine kinase PsyrB_06135 ENOG4105DRR Transcriptional regulator, GntR family PsyrB_06145 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) PsyrB_06150 ENOG4108JQ9 ABC transporter PsyrB_06155 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) PsyrB_06160 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) PsyrB_06190 ENOG4105J0Q Transcriptional regulator PsyrB_06200 ENOG4105C54 Major Facilitator superfamily PsyrB_06230 ENOG4105FFC UPF0187 protein PsyrB_06265 ENOG4105E9H Lytic Murein transglycosylase PsyrB_06400 ENOG4108HR8 type iii secretion PsyrB_06410 ENOG4105I6B RNA polymerase PsyrB_06435 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) PsyrB_06440 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) PsyrB_06445 ENOG4105VIE preprotein translocase, subunit YajC PsyrB_06450 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) PsyrB_06455 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) PsyrB_06460 ENOG4107MBR 17 kDa surface antigen PsyrB_06465 ENOG4105ECY inositol monophosphatase PsyrB_06480 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family PsyrB_06485 ENOG4105C3J Cysteine desulfurase PsyrB_06490 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins PsyrB_06495 ENOG4108Z4V iron-sulfur cluster assembly PsyrB_06500 ENOG4108SWN Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity) PsyrB_06505 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB PsyrB_06510 ENOG4108ZIT Ferredoxin, 2FE-2S PsyrB_06515 ENOG4105WVQ Fe-S assembly protein IscX PsyrB_06520 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) PsyrB_06525 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs PsyrB_06540 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) PsyrB_06545 ENOG4105CUT histidyl-tRNA synthetase PsyrB_06555 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) PsyrB_06560 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) PsyrB_06565 ENOG4105CHM Aminotransferase PsyrB_06570 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase PsyrB_06580 ENOG4108JZP Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate (By similarity) PsyrB_06585 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) PsyrB_06595 ENOG4105DR5 peptidase PsyrB_06600 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) PsyrB_06610 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) PsyrB_06615 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) PsyrB_06620 ENOG4108JUA Transcriptional regulator PsyrB_06625 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) PsyrB_06630 ENOG4105CBP Major Facilitator PsyrB_06640 ENOG41090U3 tautomerase PsyrB_06655 ENOG4107STQ Multicopper oxidase PsyrB_06660 ENOG4108Z6B deaminase PsyrB_06665 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) PsyrB_06670 ENOG4108ETH Formylglycinamide ribotide synthetase PsyrB_06690 ENOG4105P8F nudix hydrolase PsyrB_06695 ENOG4108Z0R Transferase PsyrB_06710 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR PsyrB_06715 ENOG4105CSH Transporter PsyrB_06720 ENOG4108JU6 CBS domain protein PsyrB_06730 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY PsyrB_06740 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) PsyrB_06745 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) PsyrB_06750 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) PsyrB_06755 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) PsyrB_06765 ENOG4105T95 Thiol disulfide interChange protein PsyrB_06770 ENOG4105D6E homoserine dehydrogenase PsyrB_06775 ENOG4105D98 threonine synthase PsyrB_06780 ENOG4105BZU Histidine kinase PsyrB_06790 ENOG41068CG regulatoR PsyrB_06805 ENOG4108VWS Yaeq family PsyrB_06810 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) PsyrB_06815 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase PsyrB_06845 ENOG4108KTQ Methyltransferase PsyrB_06855 ENOG4105CBS Chea signal transduction histidine kinase PsyrB_06860 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) PsyrB_06870 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) PsyrB_06875 ENOG4105CRK lysyL-tRNA synthetase PsyrB_06890 ENOG4107XM9 (LipO)protein PsyrB_06910 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) PsyrB_06915 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) PsyrB_06920 ENOG41072GX Peptidase M22 Glycoprotease PsyrB_06945 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) PsyrB_06960 ENOG4105E55 glycerol-3-phosphate acyltransferase PsyrB_06970 ENOG4105DHI Methyltransferase PsyrB_06975 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) PsyrB_06980 ENOG4107QJZ Glycosyl transferase, family 2 PsyrB_06985 ENOG4105CUZ uba thif-type nad fad binding protein PsyrB_06990 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) PsyrB_06995 ENOG4105C9B Cysteine desulfurase PsyrB_07000 ENOG4105EJ3 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity) PsyrB_07005 ENOG4105KUZ arsenate reductase PsyrB_07020 ENOG4107QSS Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity) PsyrB_07025 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) PsyrB_07030 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) PsyrB_07040 ENOG4105CE9 30S ribosomal protein S2 PsyrB_07045 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) PsyrB_07050 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) PsyrB_07060 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) PsyrB_07065 ENOG4105KNE Phosphatidate cytidylyltransferase PsyrB_07070 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) PsyrB_07075 ENOG4105DZP Membrane-associated zinc metalloprotease PsyrB_07080 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane PsyrB_07085 ENOG4105X4K outer membrane chaperone skp PsyrB_07090 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) PsyrB_07095 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) PsyrB_07100 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) PsyrB_07105 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) PsyrB_07110 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) PsyrB_07115 ENOG4105C0B DNA polymerase III (alpha subunit) PsyrB_07120 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) PsyrB_07125 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) PsyrB_07130 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) PsyrB_07135 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase PsyrB_07140 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) PsyrB_07145 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) PsyrB_07150 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) PsyrB_07155 ENOG4105EXG Transcriptional regulator PsyrB_07165 ENOG4105C4W S-formylglutathione hydrolase PsyrB_07170 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) PsyrB_07175 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) PsyrB_07180 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) PsyrB_07185 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) PsyrB_07190 ENOG4108K5P (LipO)protein PsyrB_07195 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) PsyrB_07205 ENOG4108Z4U Ferredoxin PsyrB_07210 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) PsyrB_07220 ENOG4107TH8 cina domain protein PsyrB_07225 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) PsyrB_07230 ENOG4105Y3E Modulates RecA activity (By similarity) PsyrB_07245 ENOG4106IUH DTW domain containing protein PsyrB_07260 ENOG41080IJ Diacylglycerol kinase PsyrB_07265 ENOG4105DUM transcriptional regulator, lysR family PsyrB_07270 ENOG4105DP0 ferredoxin-NADP reductase PsyrB_07275 ENOG4108R96 Methyltransferase, YaeB family PsyrB_07280 ENOG4108W15 Protein of unknown function (DUF1456) PsyrB_07285 ENOG4105FE9 pseudouridine synthase PsyrB_07290 ENOG4105K5X acetyltransferase PsyrB_07295 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) PsyrB_07305 ENOG4105DFH Transport of potassium into the cell (By similarity) PsyrB_07315 ENOG4105FF5 Membrane PsyrB_07330 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) PsyrB_07340 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) PsyrB_07345 ENOG4105J5J Outer membrane porin PsyrB_07355 ENOG41069P5 Protein slyX homolog PsyrB_07360 ENOG4105VEQ Cold shock protein PsyrB_07375 ENOG4105C9M aspartyl-trna synthetase PsyrB_07380 ENOG4105CDY transcriptional regulatory protein PsyrB_07385 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) PsyrB_07390 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) PsyrB_07395 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) PsyrB_07400 ENOG4107YD3 Thioesterase PsyrB_07405 ENOG4105E02 MotA TolQ exbB proton channel PsyrB_07410 ENOG4105M8F Biopolymer transport protein exbD tolR PsyrB_07420 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) PsyrB_07425 ENOG4105KCK Peptidoglycan-associated lipoprotein PsyrB_07430 ENOG4105UFD tol-pal system protein YbgF PsyrB_07435 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) PsyrB_07440 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) PsyrB_07460 ENOG41086NF K02433 aspartyl-tRNA(Asn) glutamyl-tRNA (Gln) amidotransferase subunit A EC 6.3.5.6 6.3.5.7 PsyrB_07465 ENOG4107QX3 carboxylase PsyrB_07475 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_07490 ENOG4105KHU inner membrane protein YohD PsyrB_07495 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) PsyrB_07500 ENOG4105ERG peptidase m48, ste24p PsyrB_07505 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) PsyrB_07515 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen PsyrB_07525 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) PsyrB_07530 ENOG4105GJM (LipO)protein PsyrB_07535 ENOG4105Q2H domain protein PsyrB_07540 ENOG4105C8V SAICAR synthetase PsyrB_07550 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase PsyrB_07555 ENOG4105CC0 LysR family Transcriptional regulator PsyrB_07570 ENOG4107R1I NAD-dependent malic enzyme PsyrB_07575 ENOG4105DIJ Phosphoethanolamine transferase PsyrB_07585 ENOG4105VNG YcgL domain-containing protein PsyrB_07590 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase PsyrB_07600 ENOG4108ZZ3 UPF0260 protein PsyrB_07620 ENOG4105E3B Multicopper oxidase PsyrB_07625 ENOG4105N1F Hnh endonuclease PsyrB_07635 ENOG4105CUG Oligopeptidase b PsyrB_07645 ENOG4105E7A Glutamine amidotransferase PsyrB_07665 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit PsyrB_07680 ENOG4105C6T cysteine synthase PsyrB_07690 ENOG4105BZU Histidine kinase PsyrB_07695 ENOG4108J8Q Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity) PsyrB_07705 ENOG4105C09 Bile acid PsyrB_07710 ENOG4105DH7 May be involved in recombination (By similarity) PsyrB_07730 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F PsyrB_07735 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase PsyrB_07750 ENOG4108V1T peptidylprolyl cis-trans isomerase PsyrB_07775 ENOG4105CN1 protease PsyrB_07785 ENOG41083B3 HAD-superfamily subfamily IB hydrolase PsyrB_07795 ENOG4105F38 ABC transporter, permease PsyrB_07830 ENOG4105DFM M18 family aminopeptidase PsyrB_07835 ENOG4105D3G Pseudouridine synthase PsyrB_07840 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) PsyrB_07845 ENOG4107QMS site-determining protein PsyrB_07850 ENOG4105K7U Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) PsyrB_07855 ENOG4105D1S lipid A biosynthesis PsyrB_07875 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) PsyrB_07910 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) PsyrB_07915 ENOG4105EUB pirin domain protein PsyrB_07925 ENOG4107QPN acyl-Coa dehydrogenase PsyrB_07930 ENOG4108TGY Glutathione S-transferase PsyrB_07935 ENOG4105DA5 (ABC) transporter PsyrB_07940 ENOG4105E3A (ABC) transporter PsyrB_07945 ENOG4108EC8 DNA internalization-related competence protein ComEC PsyrB_07955 ENOG4109015 Biopolymer transport protein exbD tolR PsyrB_07960 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) PsyrB_07965 ENOG4105W49 UPF0434 protein PsyrB_07970 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) PsyrB_07975 ENOG4105D4A Cell wall formation (By similarity) PsyrB_07980 ENOG4105C03 ribonuclease PsyrB_07990 ENOG4105EI2 Pseudouridine synthase PsyrB_08000 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) PsyrB_08005 ENOG4108UHJ MAF-like protein PsyrB_08010 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein PsyrB_08015 ENOG4105VGS 50s ribosomal protein l32 PsyrB_08020 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) PsyrB_08025 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase PsyrB_08030 ENOG4105CHR reductase PsyrB_08040 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) PsyrB_08050 ENOG4105HHA aminodeoxychorismate lyase PsyrB_08055 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) PsyrB_08060 ENOG4107QRG dna polymerase iii PsyrB_08070 ENOG4105F8V Hydrolase, tatD family PsyrB_08100 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) PsyrB_08115 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) PsyrB_08120 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase PsyrB_08125 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) PsyrB_08130 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase PsyrB_08140 ENOG4105E96 Colicin v production protein PsyrB_08145 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase PsyrB_08150 ENOG4105C28 cystathionine PsyrB_08155 ENOG4107EXU Short-chain dehydrogenase reductase Sdr PsyrB_08180 ENOG4105C7B Threonine dehydratase PsyrB_08200 ENOG4108ZX5 transcriptional regulator PsyrB_08210 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase PsyrB_08220 ENOG4105CSH Transporter PsyrB_08225 ENOG4105EU0 Major facilitator Superfamily PsyrB_08240 ENOG4105BZU Histidine kinase PsyrB_08245 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) PsyrB_08260 ENOG4105VUT cytoplasmic protein PsyrB_08270 ENOG4105CD8 aminopeptidase N PsyrB_08300 ENOG4105Z6B inner membrane protein yjfl PsyrB_08310 ENOG4106032 Glutathionylspermidine synthase PsyrB_08315 ENOG4105D25 secreted protein PsyrB_08355 ENOG4105CMD Transcriptional regulator, GntR family PsyrB_08380 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) PsyrB_08390 ENOG4105EYH Exonuclease PsyrB_08395 ENOG4107RH8 nuclease SbcCD subunit D PsyrB_08410 ENOG4107QVM von Willebrand factor, type A PsyrB_08425 ENOG4105C7R Atpase associated with various cellular activities aaa_3 PsyrB_08440 ENOG4105C7I Dehydrogenase PsyrB_08450 ENOG4107QIJ Aconitate hydratase 2 PsyrB_08460 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase PsyrB_08465 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes PsyrB_08470 ENOG4105CW7 secretion protein, HlyD family PsyrB_08475 ENOG4105C0R drug resistance transporter emrb qaca subfamily PsyrB_08485 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) PsyrB_08495 ENOG4105CX6 glutaminyL-tRNA synthetase PsyrB_08500 ENOG4105C8N cysteinyl-tRNA synthetase PsyrB_08505 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family PsyrB_08510 ENOG4108IJ9 (ABC) transporter PsyrB_08515 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) PsyrB_08525 ENOG4105EB1 binding-protein-dependent transport systems inner membrane Component PsyrB_08540 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) PsyrB_08560 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation PsyrB_08565 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) PsyrB_08570 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) PsyrB_08575 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) PsyrB_08580 ENOG4105K70 DNA-binding protein PsyrB_08585 ENOG4105EIN peptidylprolyl cis-trans isomerase PsyrB_08595 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH PsyrB_08600 ENOG4108JQ5 ABC transporter PsyrB_08605 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component PsyrB_08610 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component PsyrB_08615 ENOG4105E43 Extracellular solute-binding protein, family 5 PsyrB_08620 ENOG4105E43 Extracellular solute-binding protein, family 5 PsyrB_08625 ENOG4105E9H Lytic Murein transglycosylase PsyrB_08630 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) PsyrB_08640 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) PsyrB_08645 ENOG4107RZZ dna polymerase iii epsilon subunit PsyrB_08660 ENOG4108YYH Nadph-dependent fmn reductase PsyrB_08670 ENOG4105C1G acyl-Coa dehydrogenase PsyrB_08690 ENOG4105CJ3 phosphate transporter PsyrB_08700 ENOG4105CV8 reductase PsyrB_08705 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_08710 ENOG4108R86 Transcriptional regulator PsyrB_08725 ENOG4107QK4 glycoside hydrolase, family 3 domain protein PsyrB_08745 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein PsyrB_08770 ENOG4105CPC Aldo Keto reductase PsyrB_08805 ENOG4105CEY Amp-dependent synthetase and ligase PsyrB_08825 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_08835 ENOG4107NQ8 LysR family Transcriptional regulator PsyrB_08840 ENOG4105K6H D-cysteine desulfhydrase PsyrB_08845 ENOG4105EW9 transcriptional regulator AsnC family PsyrB_08850 ENOG4105CKW Inner membrane protein yedI PsyrB_08865 ENOG4108Z2U ureidoglycolate hydrolase PsyrB_08870 ENOG4105DHG Allantoate amidinohydrolase PsyrB_08885 ENOG4105VT2 5-hydroxyisourate hydrolase PsyrB_08900 ENOG4107QUY Guanine deaminase PsyrB_08930 ENOG4107NPY receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity) PsyrB_08935 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) PsyrB_08945 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) PsyrB_08955 ENOG4105D64 Mechanosensitive ion channel PsyrB_08970 ENOG4107QMP dna polymerase iii subunits gamma and tau PsyrB_08975 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) PsyrB_08980 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) PsyrB_08985 ENOG4105CJ0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity) PsyrB_08995 ENOG4105BZ1 (ABC) transporter PsyrB_09000 ENOG4105NBK UPF0345 protein PsyrB_09025 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) PsyrB_09030 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein PsyrB_09035 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A PsyrB_09040 ENOG4105DKK Benzoate PsyrB_09050 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family PsyrB_09070 ENOG4105EUJ GTP cyclohydrolase i PsyrB_09080 ENOG4108DG9 Smr protein MutS2 PsyrB_09095 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) PsyrB_09110 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase PsyrB_09120 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) PsyrB_09125 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) PsyrB_09130 ENOG4106YVY Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity) PsyrB_09135 ENOG4105VJY transcriptional regulator PsyrB_09145 ENOG4105JXB ankyrin repeat-containing protein PsyrB_09165 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) PsyrB_09170 ENOG4105E0M Sulfatase PsyrB_09210 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) PsyrB_09220 ENOG4105D7N magnesium and cobalt transport protein CorA PsyrB_09305 ENOG4105KT5 UmuD protein PsyrB_09310 ENOG4107MV2 Inherit from COG: Hemolysin-type calcium-binding PsyrB_09340 ENOG4105F6U Short-chain dehydrogenase reductase Sdr PsyrB_09350 ENOG4105C0D helicase PsyrB_09360 ENOG4108JA2 transcriptioN-repair coupling factor PsyrB_09380 ENOG4105CJ2 (LipO)protein PsyrB_09385 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) PsyrB_09390 ENOG4108QXE glycerophosphoryl diester phosphodiesterase PsyrB_09400 ENOG4105D60 lipoprotein releasing system transmembrane protein PsyrB_09405 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) PsyrB_09410 ENOG4105D60 lipoprotein releasing system transmembrane protein PsyrB_09415 ENOG4107R1K Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) PsyrB_09430 ENOG410903C (LipO)protein PsyrB_09440 ENOG4108ZXC Two component transcriptional regulator, luxr family PsyrB_09450 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) PsyrB_09460 ENOG4105KT5 UmuD protein PsyrB_09470 ENOG4105BZU Histidine kinase PsyrB_09495 ENOG4107SFI Major Facilitator superfamily PsyrB_09505 ENOG4108JPW Aminotransferase PsyrB_09520 ENOG4105C5Q Transcriptional regulator PsyrB_09570 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) PsyrB_09575 ENOG41068KF Universal stress protein PsyrB_09580 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase PsyrB_09585 ENOG4105BZU Histidine kinase PsyrB_09640 ENOG4105FDK ABC transporter PsyrB_09710 ENOG4105IBP Cyclic peptide transporter PsyrB_09735 ENOG4105ENJ RND efflux system, outer membrane lipoprotein PsyrB_09740 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) PsyrB_09745 ENOG4105DJY efflux transporter, rnd family, mfp subunit PsyrB_09750 ENOG4107SQI penicillin amidase PsyrB_09760 ENOG4105CGF Aromatic amino acid aminotransferase PsyrB_09765 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) PsyrB_09770 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) PsyrB_09800 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) PsyrB_09810 ENOG4105BZU Histidine kinase PsyrB_09815 ENOG4108MP6 LysR family Transcriptional regulator PsyrB_09820 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) PsyrB_09825 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) PsyrB_09830 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) PsyrB_09835 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) PsyrB_09840 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 PsyrB_09845 ENOG4108RTU Aldolase PsyrB_09850 ENOG4105CXK mandelate racemase muconate lactonizing PsyrB_09855 ENOG4105DJB Major Facilitator Superfamily PsyrB_09860 ENOG4107HP6 Transcriptional regulator PsyrB_09865 ENOG4105DQ4 alcohol dehydrogenase PsyrB_09870 ENOG4105CF7 AraC family transcriptional regulator PsyrB_09875 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase PsyrB_09880 ENOG4105BZJ Electron transfer flavoprotein PsyrB_09885 ENOG4105C10 Electron transfer flavoprotein PsyrB_09905 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family PsyrB_09920 ENOG4105VV6 START domain-containing protein PsyrB_09925 ENOG4105BZN citrate synthase PsyrB_09930 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit PsyrB_09935 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein PsyrB_09940 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) PsyrB_09945 ENOG4105E33 succinate dehydrogenase PsyrB_09955 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 PsyrB_09960 ENOG4105C7S Dehydrogenase PsyrB_09965 ENOG4107QN2 dihydrolipoyl dehydrogenase PsyrB_09975 ENOG4105CMV Succinyl-CoA synthetase subunit beta PsyrB_09980 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha PsyrB_09990 ENOG4105CWM branched-chain amino acid transport system II carrier protein PsyrB_10000 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) PsyrB_10020 ENOG4108RKI Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity) PsyrB_10025 ENOG4105BZU Histidine kinase PsyrB_10030 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase PsyrB_10040 ENOG4108BY2 phosphohistidine phosphatase PsyrB_10045 ENOG4105KA0 thioesterase Superfamily protein PsyrB_10065 ENOG4105IPI Membrane PsyrB_10075 ENOG4105E0F Histidine kinase PsyrB_10080 ENOG4105DPZ Two component transcriptional regulator (Winged helix family PsyrB_10110 ENOG4105CW0 outer membrane usher protein PsyrB_10115 ENOG4105GQR Chaperone PsyrB_10150 ENOG4105VJY transcriptional regulator PsyrB_10160 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) PsyrB_10165 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) PsyrB_10170 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) PsyrB_10175 ENOG4105C08 Histidine kinase PsyrB_10180 ENOG4105EEX Two component transcriptional regulator (Winged helix family PsyrB_10190 ENOG4105C7R Atpase associated with various cellular activities aaa_3 PsyrB_10200 ENOG4105F8C transglutaminase domain-containing protein PsyrB_10225 ENOG4105F8V Hydrolase, tatD family PsyrB_10235 ENOG4108VGI doxx family PsyrB_10250 ENOG4108RRZ Transcription elongation factor GreB PsyrB_10255 ENOG4105CV6 ABC transporter, permease PsyrB_10260 ENOG4108I0Y (ABC) transporter PsyrB_10265 ENOG4108UJV acyl-CoA thioesterase i PsyrB_10275 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein PsyrB_10295 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) PsyrB_10300 ENOG41084M5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) PsyrB_10315 ENOG4107R11 Transcriptional regulator PsyrB_10325 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein PsyrB_10330 ENOG4105CRQ synthase (Component I) PsyrB_10345 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) PsyrB_10350 ENOG4105DRR Transcriptional regulator, GntR family PsyrB_10355 ENOG4105CR4 methylisocitrate lyase PsyrB_10360 ENOG4105BZN citrate synthase PsyrB_10365 ENOG4108I0Z Aconitate hydratase PsyrB_10370 ENOG4105C7F AcnD-accessory protein PrpF PsyrB_10375 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) PsyrB_10390 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) PsyrB_10415 ENOG4105CDV Ompa motb domain protein PsyrB_10425 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) PsyrB_10430 ENOG4108IFG nitrite reductase, (NAD(P)H) PsyrB_10440 ENOG4105D9P serine threonine protein kinase PsyrB_10470 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) PsyrB_10475 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) PsyrB_10485 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) PsyrB_10495 ENOG4105BZU Histidine kinase PsyrB_10505 ENOG41090ED Protein with unknown function (DUF469) PsyrB_10515 ENOG4108WQH regulatoR PsyrB_10555 ENOG4105DDW LysR family Transcriptional regulator PsyrB_10560 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta PsyrB_10565 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha PsyrB_10570 ENOG4105D2S major facilitator superfamily PsyrB_10575 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase PsyrB_10580 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase PsyrB_10585 ENOG41090KI Outer membrane porin PsyrB_10600 ENOG4108I5G Major Facilitator superfamily PsyrB_10610 ENOG4108W9H Tetr family transcriptional regulator PsyrB_10615 ENOG4107S9B Shikimate dehydrogenase PsyrB_10620 ENOG4105D3G Pseudouridine synthase PsyrB_10630 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) PsyrB_10635 ENOG4108RIR Molybdenum cofactor biosynthesis protein PsyrB_10640 ENOG4105CVM Molybdenum cofactor synthesis domain protein PsyrB_10645 ENOG4108KBE Glycosyl transferase, family 2 PsyrB_10650 ENOG4105CKD glutathione-regulated potassium-efflux system protein PsyrB_10675 ENOG4105DG4 malate L-lactate dehydrogenase PsyrB_10690 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) PsyrB_10715 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator PsyrB_10720 ENOG4105C2J ABC transporter PsyrB_10725 ENOG4105CNN ABC, transporter PsyrB_10730 ENOG4105ETE Transcriptional regulator (LacI family PsyrB_10735 ENOG4108RVA ribokinase PsyrB_10740 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) PsyrB_10770 ENOG4105C22 threonyL-tRNA synthetase PsyrB_10775 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) PsyrB_10790 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) PsyrB_10795 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) PsyrB_10800 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) PsyrB_10805 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) PsyrB_10820 ENOG4107RP9 extracellular solute-binding protein, family 3 PsyrB_10825 ENOG4105C26 Dehydrogenase PsyrB_10830 ENOG4105CI0 Citrate lyase PsyrB_10835 ENOG4108M9J MaoC like domain protein PsyrB_10840 ENOG4105C10 Electron transfer flavoprotein PsyrB_10845 ENOG4105BZJ Electron transfer flavoprotein PsyrB_10855 ENOG4105C1G acyl-Coa dehydrogenase PsyrB_10860 ENOG4105DTI Phosphonopyruvate decarboxylase PsyrB_10870 ENOG4105CSH Transporter PsyrB_10895 ENOG4108WYP Transcriptional regulator PsyrB_10900 ENOG41061TZ Short-chain dehydrogenase reductase Sdr PsyrB_10905 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme PsyrB_10910 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein PsyrB_10920 ENOG4107SDU Methyl-accepting chemotaxis PsyrB_10925 ENOG4105YVS arsR family transcriptional regulator PsyrB_10930 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase PsyrB_10955 ENOG4108EI5 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) PsyrB_10960 ENOG4105CM9 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) PsyrB_10965 ENOG4105CQM Urea amidohydrolase subunit alpha PsyrB_10970 ENOG4108F09 Urease subunit gamma beta PsyrB_10975 ENOG4107YEM Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) PsyrB_10980 ENOG4105P8G Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity) PsyrB_10985 ENOG4108IV0 ABC, transporter PsyrB_10990 ENOG4105C0Z ABC transporter PsyrB_11000 ENOG4105C32 Amino acid ABC transporter (Permease) PsyrB_11005 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein PsyrB_11020 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein PsyrB_11030 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) PsyrB_11035 ENOG4105GVF (ABC) transporter PsyrB_11060 ENOG4107SDU Methyl-accepting chemotaxis PsyrB_11085 ENOG4105JQN Transcriptional regulator PsyrB_11090 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_11100 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) PsyrB_11115 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) PsyrB_11190 ENOG4108NVR Methyl-accepting chemotaxis PsyrB_11195 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_11205 ENOG4108UQ8 endoribonuclease L-psp PsyrB_11210 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) PsyrB_11220 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_11225 ENOG4105D5T phosphonate abc transporter PsyrB_11230 ENOG4105EHI Phosphonate ABC transporter, periplasmic PsyrB_11240 ENOG4107RJJ Transcriptional regulator PsyrB_11255 ENOG4105EKV Phosphonate metabolism protein PsyrB_11260 ENOG4105FT8 Phosphonate metabolism PsyrB_11265 ENOG4105ENV phosphonate C-P lyase system protein PhnK PsyrB_11270 ENOG4105HRV phosphonate c-p lyase system protein phnl PsyrB_11275 ENOG4105FD8 phosphonate metabolism protein PhnM PsyrB_11280 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) PsyrB_11285 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein PsyrB_11290 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) PsyrB_11310 ENOG4105C3U ABC transporter PsyrB_11315 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component PsyrB_11320 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component PsyrB_11330 ENOG4105EXG Transcriptional regulator PsyrB_11335 ENOG4105DZA Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity) PsyrB_11360 ENOG4105EYU Glutamine amido-transferase PsyrB_11365 ENOG4105M90 Glutamate synthase alpha subunit domain protein PsyrB_11370 ENOG4105CBC glutamate synthase PsyrB_11375 ENOG4105BZU Histidine kinase PsyrB_11385 ENOG4108M8W Monooxygenase PsyrB_11395 ENOG4105FBW Monooxygenase PsyrB_11405 ENOG4105BZS acriflavin resistance protein PsyrB_11410 ENOG4105C1P efflux transporter, rnd family, mfp subunit PsyrB_11415 ENOG4105RJZ Transcriptional regulator PsyrB_11420 ENOG4108ZX6 Electron transport protein SCO1 SenC PsyrB_11430 ENOG4105DQ6 Transposase PsyrB_11445 ENOG4105WQ5 TonB family PsyrB_11455 ENOG4105SG9 biopolymer transport protein, ExbD PsyrB_11460 ENOG4107RNH Outer membrane receptor FepA PsyrB_11465 ENOG4105MP9 class II Aldolase PsyrB_11470 ENOG4105CSV Glutaminase PsyrB_11475 ENOG4107QS8 (LipO)protein PsyrB_11490 ENOG4105CPC Aldo Keto reductase PsyrB_11495 ENOG4107EXU Short-chain dehydrogenase reductase Sdr PsyrB_11500 ENOG4105BZP glycoside hydrolase 15-related PsyrB_11520 ENOG4105IQ5 FAD linked oxidase domain protein PsyrB_11535 ENOG4105C54 Major Facilitator superfamily PsyrB_11540 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) PsyrB_11545 ENOG4105C54 Major Facilitator superfamily PsyrB_11575 ENOG4105ECR NmrA family PsyrB_11580 ENOG4105KVH Transcriptional regulator PsyrB_11585 ENOG4105CJN penicillin-binding protein PsyrB_11590 ENOG4105C7K acetolactate synthase PsyrB_11595 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_11620 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) PsyrB_11630 ENOG4105CY5 solute-binding protein PsyrB_11650 ENOG4105D38 putrescine abc transporter PsyrB_11655 ENOG4105F38 ABC transporter, permease PsyrB_11660 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) PsyrB_11665 ENOG4108K8U Glycerol operon regulatory protein PsyrB_11670 ENOG4108NVR Methyl-accepting chemotaxis PsyrB_11675 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) PsyrB_11700 ENOG4105EE5 Membrane protein terC PsyrB_11735 ENOG4108WC9 type VI secretion system effector, hcp1 family PsyrB_11775 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit PsyrB_11820 ENOG4105CUT histidyl-tRNA synthetase PsyrB_11825 ENOG4105WCN acetyltransferase PsyrB_11830 ENOG4108NPY Ankyrin repeat protein PsyrB_11850 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_11855 ENOG4105CBN LysR family transcriptional regulator PsyrB_11860 ENOG4105C8Y Acetylornithine aminotransferase PsyrB_11875 ENOG4105CQ2 DNA polymerase PsyrB_11885 ENOG4105JAB phenazine biosynthesis protein, phzf family PsyrB_11905 ENOG4105CC5 ABC transporter PsyrB_11910 ENOG4107SIG periplasmic solute binding protein PsyrB_11915 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) PsyrB_11920 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein PsyrB_11925 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator PsyrB_11930 ENOG4105C2J ABC transporter PsyrB_11935 ENOG4105CNN ABC, transporter PsyrB_11940 ENOG4105US7 Histidine kinase PsyrB_11945 ENOG4105ETX regulatoR PsyrB_11950 ENOG4105GNX MltA-interacting MipA family protein PsyrB_11955 ENOG4107SCK Monooxygenase PsyrB_11990 ENOG41074H6 response regulator PsyrB_11995 ENOG4105BZU Histidine kinase PsyrB_12005 ENOG4105DWT malate dehydrogenase (quinone) PsyrB_12010 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit PsyrB_12015 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding PsyrB_12020 ENOG4105C7W Xanthine dehydrogenase PsyrB_12025 ENOG4107XAN XdhC and CoxI family PsyrB_12035 ENOG4108MEJ flavin reductase domain protein PsyrB_12040 ENOG4105C26 Dehydrogenase PsyrB_12045 ENOG4105EGI Transcriptional regulator PsyrB_12055 ENOG4105EJC lysr family transcriptional regulator PsyrB_12060 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) PsyrB_12070 ENOG4105F38 ABC transporter, permease PsyrB_12075 ENOG4107RUE extracellular solute-binding protein family 1 PsyrB_12080 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) PsyrB_12090 ENOG4105E09 nadh pyrophosphatase PsyrB_12105 ENOG4105C26 Dehydrogenase PsyrB_12110 ENOG4108MXF Alpha Beta Hydrolase PsyrB_12120 ENOG4105E2A Dehydrogenase PsyrB_12125 ENOG4105CYX Short-chain dehydrogenase reductase Sdr PsyrB_12140 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) PsyrB_12150 ENOG4105DY8 decarboxylase PsyrB_12155 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr PsyrB_12165 ENOG41061WM D-Alanyl-D-Alanine PsyrB_12185 ENOG4105F9E Shikimate 5-dehydrogenase PsyrB_12190 ENOG4108YXG UPF0502 protein PsyrB_12200 ENOG4108SUT Major Facilitator Superfamily PsyrB_12205 ENOG41063Z6 transcriptional regulator, lysR family PsyrB_12215 ENOG4105EE5 Membrane protein terC PsyrB_12230 ENOG4105CJP fad dependent oxidoreductase PsyrB_12300 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) PsyrB_12305 ENOG4105DQ4 alcohol dehydrogenase PsyrB_12310 ENOG4105BZU Histidine kinase PsyrB_12325 ENOG4105CMG Carbohydrate kinase PsyrB_12330 ENOG4105DEI Mannitol dehydrogenase PsyrB_12345 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component PsyrB_12350 ENOG4107T3P ABC, transporter PsyrB_12370 ENOG4105CK6 Two component transcriptional regulator (Winged helix family PsyrB_12375 ENOG4105BZU Histidine kinase PsyrB_12380 ENOG4105BZU Histidine kinase PsyrB_12385 ENOG4107Z5C methylesterase PsyrB_12390 ENOG4105BZU Histidine kinase PsyrB_12405 ENOG4105EHU Circadian clock protein KaiC PsyrB_12410 ENOG4105E39 Enoyl-CoA hydratase PsyrB_12415 ENOG4105E09 nadh pyrophosphatase PsyrB_12425 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase PsyrB_12445 ENOG4105ERU peptidase PsyrB_12455 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) PsyrB_12465 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator PsyrB_12470 ENOG4105C3R Methionine synthase PsyrB_12480 ENOG4107RUK Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity) PsyrB_12490 ENOG4108VUG Enoyl-CoA hydratase PsyrB_12495 ENOG4107QX3 carboxylase PsyrB_12500 ENOG4105C1G acyl-Coa dehydrogenase PsyrB_12510 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase PsyrB_12515 ENOG4108Z6Z Transcriptional regulator PsyrB_12525 ENOG4105C1G acyl-Coa dehydrogenase PsyrB_12530 ENOG4107QKZ Ompa motb domain protein PsyrB_12535 ENOG4105CGK Exodeoxyribonuclease III PsyrB_12545 ENOG4105CFU surface antigen PsyrB_12555 ENOG4105CBN LysR family transcriptional regulator PsyrB_12560 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) PsyrB_12565 ENOG4105ENT Efflux transporter rnd family, mfp subunit PsyrB_12575 ENOG4105BZS acriflavin resistance protein PsyrB_12580 ENOG4105ENJ RND efflux system, outer membrane lipoprotein PsyrB_12585 ENOG4105BZU Histidine kinase PsyrB_12590 ENOG4105CYX Short-chain dehydrogenase reductase Sdr PsyrB_12600 ENOG4105EP6 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity) PsyrB_12610 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) PsyrB_12620 ENOG4105F9N Major Facilitator Superfamily PsyrB_12625 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) PsyrB_12630 ENOG4105C5H ABC transporter PsyrB_12650 ENOG4106JH6 (LipO)protein PsyrB_12660 ENOG4108TGY Glutathione S-transferase PsyrB_12690 ENOG4105E5Q amino acid AbC transporter PsyrB_12695 ENOG4105E5Q amino acid AbC transporter PsyrB_12700 ENOG4105CDA abc transporter atp-binding protein PsyrB_12720 ENOG4107SS6 2-dehydro-3-deoxygluconokinase PsyrB_12725 ENOG41088T4 Helicase IV PsyrB_12735 ENOG4108HM4 ABC transporter PsyrB_12745 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component PsyrB_12750 ENOG4105GVF (ABC) transporter PsyrB_12760 ENOG4107SET aldo keto reductase PsyrB_12765 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) PsyrB_12780 ENOG4105C0B DNA polymerase III (alpha subunit) PsyrB_12790 ENOG4105D7N magnesium and cobalt transport protein CorA PsyrB_12795 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) PsyrB_12810 ENOG4105CPN adenine deaminase PsyrB_12820 ENOG4105CSH Transporter PsyrB_12825 ENOG4108PZW LysR family Transcriptional regulator PsyrB_12830 ENOG4105ETT transcriptional Regulator, LysR family PsyrB_12835 ENOG4105CQB FAD linked oxidase domain protein PsyrB_12845 ENOG4105BZU Histidine kinase PsyrB_12860 ENOG4105E1J oxidoreductase PsyrB_12865 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component PsyrB_12875 ENOG4105C3U ABC transporter PsyrB_12885 ENOG4105DEF Extracellular solute-binding protein, family 5 PsyrB_12900 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) PsyrB_12995 ENOG4105EQ2 LysR family Transcriptional regulator PsyrB_13010 ENOG4105CMT Dihydroxyacetone kinase PsyrB_13015 ENOG4105CPQ Dehydrogenase PsyrB_13020 ENOG4105CHR reductase PsyrB_13025 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator PsyrB_13030 ENOG4105CNN ABC, transporter PsyrB_13035 ENOG4105C2J ABC transporter PsyrB_13040 ENOG4108YZG isomerase PsyrB_13045 ENOG4105DKT Transcriptional regulator PsyrB_13050 ENOG4105DZG Dehydrogenase PsyrB_13075 ENOG4107RGH Aldehyde dehydrogenase PsyrB_13080 ENOG4108SF5 RNA Polymerase PsyrB_13085 ENOG4108S3W Anti-feci sigma factor, fecr PsyrB_13095 ENOG4108JPW Aminotransferase PsyrB_13100 ENOG4105DUU IucA IucC family protein PsyrB_13105 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) PsyrB_13110 ENOG4105C0R drug resistance transporter emrb qaca subfamily PsyrB_13115 ENOG4105DUU IucA IucC family protein PsyrB_13125 ENOG4105DJU Siderophore biosynthesis protein PsyrB_13130 ENOG4108MES Periplasmic binding protein PsyrB_13135 ENOG4105DQ5 transport system permease protein PsyrB_13140 ENOG4108IHU transport system permease protein PsyrB_13145 ENOG4105E0A ABC, transporter PsyrB_13155 ENOG4105JSC dimethylmenaquinone methyltransferase PsyrB_13160 ENOG4107SDU Methyl-accepting chemotaxis PsyrB_13165 ENOG4105BZU Histidine kinase PsyrB_13195 ENOG4105DJY efflux transporter, rnd family, mfp subunit PsyrB_13215 ENOG4105ENJ RND efflux system, outer membrane lipoprotein PsyrB_13240 ENOG4105CEY Amp-dependent synthetase and ligase PsyrB_13250 ENOG4105IBP Cyclic peptide transporter PsyrB_13270 ENOG4105DJY efflux transporter, rnd family, mfp subunit PsyrB_13275 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) PsyrB_13310 ENOG4105KAV tspo and mbr like protein PsyrB_13315 ENOG4105MWK D-amino acid dehydrogenase, small subunit PsyrB_13320 ENOG4105DWV Homoserine O-trans-acetylase PsyrB_13390 ENOG4105JAB phenazine biosynthesis protein, phzf family PsyrB_13400 ENOG4105DND Transcriptional regulator PsyrB_13405 ENOG4105D4T Citrate transporter PsyrB_13420 ENOG4105FDP GntR family transcriptional regulator PsyrB_13430 ENOG4108JQ7 (ABC) transporter PsyrB_13445 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component PsyrB_13450 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) PsyrB_13465 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase PsyrB_13470 ENOG4105CKK Glycosyl transferase, family 2 PsyrB_13475 ENOG4108F26 Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) PsyrB_13480 ENOG4105F73 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) PsyrB_13485 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) PsyrB_13490 ENOG41060GT Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) PsyrB_13500 ENOG4105C6Y Udp-glucose 6-dehydrogenase PsyrB_13520 ENOG4105BZU Histidine kinase PsyrB_13540 ENOG4105CMR udp-glucose 4-epimerase PsyrB_13545 ENOG4107VRI Transcriptional regulator PsyrB_13585 ENOG4106NZI LysR family Transcriptional regulator PsyrB_13600 ENOG4105EQX glucarate dehydratase PsyrB_13605 ENOG4105DY2 Paraquat-inducible protein b PsyrB_13625 ENOG4105CT1 (ABC) transporter PsyrB_13630 ENOG4105CDA abc transporter atp-binding protein PsyrB_13635 ENOG4105DRP amino acid AbC transporter PsyrB_13650 ENOG4105E7W lamb ycsf family protein PsyrB_13660 ENOG4107R7A Allophanate hydrolase subunit 2 PsyrB_13665 ENOG4105P4J Allophanate hydrolase, subunit 1 PsyrB_13670 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase PsyrB_13675 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein PsyrB_13685 ENOG4105CHM Aminotransferase PsyrB_13695 ENOG4105J5J Outer membrane porin PsyrB_13740 ENOG4105CHU acetyl-coa acetyltransferase PsyrB_13745 ENOG4105E4E Thioester reductase domain-containing protein PsyrB_13755 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase PsyrB_13765 ENOG4105EPF Outer membrane porin PsyrB_13770 ENOG4108SC4 )-transporter PsyrB_13815 ENOG4105ECQ AraC Family Transcriptional Regulator PsyrB_13820 ENOG4107S1E Beta-lactamase PsyrB_13830 ENOG4105CCF Lysine exporter protein (Lyse ygga) PsyrB_13855 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) PsyrB_13860 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) PsyrB_13870 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) PsyrB_13880 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family PsyrB_13885 ENOG4108WUH Transcriptional regulator, TetR family PsyrB_13890 ENOG4107QWG 2-Nitropropane dioxygenase PsyrB_13895 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein PsyrB_13900 ENOG4105E0C molybdate abc transporter PsyrB_13905 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) PsyrB_13955 ENOG4105NVB glycoside hydrolase, family 19 PsyrB_14275 ENOG4107R4J Chloride channel PsyrB_14300 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) PsyrB_14310 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii PsyrB_14315 ENOG4105C4M (Ubiquinol oxidase) subunit I PsyrB_14330 ENOG4105DUM transcriptional regulator, lysR family PsyrB_14355 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i PsyrB_14360 ENOG4105Y7H Cytochrome PsyrB_14375 ENOG4105F5W AtP-binding protein PsyrB_14540 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) PsyrB_14550 ENOG4108M1A Chitin-binding protein PsyrB_14565 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) PsyrB_14595 ENOG4105R0I Feruloyl esterase PsyrB_14600 ENOG4105ENJ RND efflux system, outer membrane lipoprotein PsyrB_14605 ENOG4105BZS acriflavin resistance protein PsyrB_14610 ENOG4105C1P efflux transporter, rnd family, mfp subunit PsyrB_14615 ENOG4105EB3 Histidine kinase PsyrB_14620 ENOG4105E3W Two component transcriptional regulator (Winged helix family PsyrB_14645 ENOG4105CNN ABC, transporter PsyrB_14650 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane PsyrB_14655 ENOG4105C2J ABC transporter PsyrB_14685 ENOG4105T16 Transcriptional regulator (AraC family) PsyrB_14690 ENOG4105C93 Xylose Isomerase PsyrB_14695 ENOG4105DFW ABC transporter PsyrB_14700 ENOG4105C2J ABC transporter PsyrB_14705 ENOG4108HWW ABC transporter PsyrB_14720 ENOG4105EAB amino acid AbC transporter PsyrB_14725 ENOG4105CDA abc transporter atp-binding protein PsyrB_14735 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) PsyrB_14760 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) PsyrB_14765 ENOG4105WH1 Two component transcriptional regulator luxr family PsyrB_14785 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) PsyrB_14790 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) PsyrB_14800 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component PsyrB_14805 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component PsyrB_14810 ENOG4108JQ5 ABC transporter PsyrB_14815 ENOG4105CZX twitching motility protein PsyrB_14820 ENOG4105KQ5 peptidylprolyl cis-trans isomerase PsyrB_14860 ENOG4105C9U ATP-dependent DNA helicase RecQ PsyrB_14865 ENOG4105ECQ AraC Family Transcriptional Regulator PsyrB_14875 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme PsyrB_14880 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) PsyrB_14895 ENOG4108KD5 ADP-ribosylation crystallin J1 PsyrB_14905 ENOG4108TFM Kinase, PfkB family PsyrB_14925 ENOG4105F27 Major Facilitator PsyrB_14930 ENOG4108IND Tetr family transcriptional regulator PsyrB_14935 ENOG4105BZ1 (ABC) transporter PsyrB_14950 ENOG41061MD high-affinity nickel-transporter PsyrB_14960 ENOG4108WUH Transcriptional regulator, TetR family PsyrB_14965 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase PsyrB_14990 ENOG4105EJC lysr family transcriptional regulator PsyrB_15000 ENOG4105BZU Histidine kinase PsyrB_15005 ENOG4105CT1 (ABC) transporter PsyrB_15010 ENOG4105CDA abc transporter atp-binding protein PsyrB_15020 ENOG4105DRP amino acid AbC transporter PsyrB_15055 ENOG4107R4J Chloride channel PsyrB_15080 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) PsyrB_15090 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii PsyrB_15095 ENOG4105C4M (Ubiquinol oxidase) subunit I PsyrB_15110 ENOG4105DUM transcriptional regulator, lysR family PsyrB_15135 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i PsyrB_15140 ENOG4105Y7H Cytochrome PsyrB_15155 ENOG4105F5W AtP-binding protein PsyrB_15185 ENOG4107YUH hydrolase PsyrB_15200 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b PsyrB_15220 ENOG4108QBQ Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity) PsyrB_15230 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component PsyrB_15235 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component PsyrB_15265 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_15305 ENOG4108JU3 Alkyl hydroperoxide reductase PsyrB_15310 ENOG4105D3R alkyl hydroperoxide reductase PsyrB_15325 ENOG4105CQZ Histidine kinase PsyrB_15330 ENOG4105DC8 reductase PsyrB_15360 ENOG4105CF1 Alkylated DNA repair protein PsyrB_15365 ENOG4105BZP glycoside hydrolase 15-related PsyrB_15370 ENOG4105DQF Hydrolase PsyrB_15375 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase PsyrB_15380 ENOG4108J5G 6-phosphogluconate dehydrogenase PsyrB_15395 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) PsyrB_15400 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) PsyrB_15405 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) PsyrB_15455 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) PsyrB_15460 ENOG4105EQ2 LysR family Transcriptional regulator PsyrB_15465 ENOG4105F2Z 3-oxoadipate enol-lactonase PsyrB_15480 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) PsyrB_15495 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_15515 ENOG4105CTK cobaltochelatase, cobn subunit PsyrB_15520 ENOG4107QRP cobalamin biosynthesis protein CobW PsyrB_15540 ENOG4105CIA precorrin-4 C(11)-methyltransferase PsyrB_15550 ENOG4108XM1 transcriptional regulator AsnC family PsyrB_15595 ENOG4105E39 Enoyl-CoA hydratase PsyrB_15600 ENOG4105CHU acetyl-coa acetyltransferase PsyrB_15625 ENOG4107QK4 glycoside hydrolase, family 3 domain protein PsyrB_15655 ENOG4105D4Y metalloprotease PsyrB_15665 ENOG4105F1S paraquat-inducible protein a PsyrB_15670 ENOG4105F1S paraquat-inducible protein a PsyrB_15675 ENOG4105DY2 Paraquat-inducible protein b PsyrB_15690 ENOG4105CC0 LysR family Transcriptional regulator PsyrB_15695 ENOG4105EUB pirin domain protein PsyrB_15700 ENOG4107S5I aldo keto reductase PsyrB_15705 ENOG410642W LysR family Transcriptional regulator PsyrB_15730 ENOG4105CE7 Amidase, hydantoinase carbamoylase family PsyrB_15735 ENOG4105E98 transcriptional regulator DeoR family PsyrB_15740 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) PsyrB_15745 ENOG4105QNJ serralysin (EC 3.4.24.40) PsyrB_15760 ENOG4105HEI LysR family (Transcriptional regulator PsyrB_15775 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) PsyrB_15790 ENOG4105EA8 2-Nitropropane dioxygenase PsyrB_15800 ENOG4105JSC dimethylmenaquinone methyltransferase PsyrB_15805 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) PsyrB_15810 ENOG4105DF3 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity) PsyrB_15820 ENOG4105F2I Transposase PsyrB_15825 ENOG4105F2I Transposase PsyrB_15835 ENOG41067NU PsyrB_15850 ENOG41067NU PsyrB_15855 ENOG4108UMS Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity) PsyrB_15870 ENOG4105CKT filamentous hemagglutinin PsyrB_15875 ENOG4105D5K Hemolysin activator protein PsyrB_15900 ENOG4105ENJ RND efflux system, outer membrane lipoprotein PsyrB_15905 ENOG4105E3W Two component transcriptional regulator (Winged helix family PsyrB_15910 ENOG4105EB3 Histidine kinase PsyrB_15915 ENOG4105CHH sulfate transporter PsyrB_15920 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family PsyrB_15935 ENOG4105ETX regulatoR PsyrB_15945 ENOG4108WMR Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core (By similarity) PsyrB_15955 ENOG4105EHG Permease protein PsyrB_15960 ENOG4105E0A ABC, transporter PsyrB_15965 ENOG4105CFP Peptidase U32 PsyrB_15975 ENOG4107QZF nitrite reductase NADPH large subunit PsyrB_15980 ENOG4107QZF nitrite reductase NADPH large subunit PsyrB_15985 ENOG4105DWV Homoserine O-trans-acetylase PsyrB_16000 ENOG4105E2Z phosphate ABC transporter (Permease PsyrB_16005 ENOG4105C8U phosphate abc transporter PsyrB_16010 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) PsyrB_16025 ENOG4105F2V VRR-NUC domain-containing protein PsyrB_16035 ENOG4107RSM transcriptional regulator PsyrB_16040 ENOG4108KK1 membrane protein AbrB duplication PsyrB_16045 ENOG4107QKS N-acylglucosamine 2-epimerase PsyrB_16055 ENOG4105BZW Glycerate kinase PsyrB_16060 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR PsyrB_16090 ENOG4108JQ1 Dehydrogenase PsyrB_16110 ENOG4105S64 Formate nitrite transporter PsyrB_16115 ENOG4105CK6 Two component transcriptional regulator (Winged helix family PsyrB_16125 ENOG4108YI3 3-hydroxyacyl-CoA-acyl carrier protein transferase PsyrB_16130 ENOG4105ENT Efflux transporter rnd family, mfp subunit PsyrB_16135 ENOG4105DJY efflux transporter, rnd family, mfp subunit PsyrB_16140 ENOG4105BZS acriflavin resistance protein PsyrB_16150 ENOG4107RGD Major Facilitator superfamily PsyrB_16170 ENOG4105EQ0 Major Facilitator superfamily PsyrB_16185 ENOG4105GVR general secretion pathway protein D PsyrB_16205 ENOG4105UV2 general secretion pathway protein K PsyrB_16220 ENOG41069X0 general secretion pathway protein h PsyrB_16230 ENOG4105D7Q type ii secretion system PsyrB_16235 ENOG4107QHF type ii secretion system protein e PsyrB_16245 ENOG4107QK4 glycoside hydrolase, family 3 domain protein PsyrB_16250 ENOG4108W9H Tetr family transcriptional regulator PsyrB_16260 ENOG4105DUM transcriptional regulator, lysR family PsyrB_16265 ENOG4105CZJ Aldehyde dehydrogenase PsyrB_16275 ENOG4105DFG type I secretion outer membrane protein PsyrB_16280 ENOG4107QZV Type I secretion membrane fusion protein PsyrB_16285 ENOG4108JJ6 Type I secretion system ATPase PsyrB_16290 ENOG41065N1 inhibitor PsyrB_16295 ENOG4105QNJ serralysin (EC 3.4.24.40) PsyrB_16300 ENOG4108MN8 Membrane PsyrB_16310 ENOG4105F04 LysR family Transcriptional regulator PsyrB_16320 ENOG4105CSH Transporter PsyrB_16325 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) PsyrB_16330 ENOG4108ZKU Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) PsyrB_16345 ENOG4108I0Q anthranilate phosphoribosyltransferase PsyrB_16350 ENOG4105CHF Glutathione S-transferase PsyrB_16355 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) PsyrB_16360 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) PsyrB_16370 ENOG4105D1H recombination factor protein RarA PsyrB_16375 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) PsyrB_16380 ENOG4105CNU cell division protein FtsK PsyrB_16385 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) PsyrB_16390 ENOG4105DWA May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate PsyrB_16395 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) PsyrB_16400 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit PsyrB_16405 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) PsyrB_16410 ENOG4105VEQ Cold shock protein PsyrB_16415 ENOG4105E9K Isocitrate dehydrogenase PsyrB_16425 ENOG4105EXG Transcriptional regulator PsyrB_16435 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) PsyrB_16440 ENOG41075W9 High frequency lysogenization protein HflD homolog PsyrB_16445 ENOG4107QTF adenylosuccinate lyase PsyrB_16450 ENOG4105EZE Cupin 4 family protein PsyrB_16465 ENOG4108I9X Isocitrate lyase PsyrB_16470 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain PsyrB_16475 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) PsyrB_16480 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) PsyrB_16485 ENOG4105GKE subunit e PsyrB_16490 ENOG4107QIZ NADH dehydrogenase PsyrB_16495 ENOG4108IEH NADH dehydrogenase subunit g PsyrB_16500 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) PsyrB_16505 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) PsyrB_16510 ENOG4107UFS subunit j PsyrB_16515 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) PsyrB_16520 ENOG4105D65 subunit l PsyrB_16525 ENOG4105C8S subunit m PsyrB_16530 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) PsyrB_16535 ENOG4108REF Sporulation integral membrane protein ytvi PsyrB_16540 ENOG4105IFJ Histidine kinase PsyrB_16545 ENOG4105XJC Two component transcriptional regulator (Winged helix family PsyrB_16560 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase PsyrB_16575 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase PsyrB_16610 ENOG4107AQZ Membrane PsyrB_16625 ENOG4105C3J Cysteine desulfurase PsyrB_16645 ENOG4105KJF protein tyrosine phosphatase PsyrB_16650 ENOG4108F2G Chain length determinant protein PsyrB_16670 ENOG4108TJN glycosyl transferase group 1 PsyrB_16675 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) PsyrB_16680 ENOG4105D3Q Sugar transferase PsyrB_16685 ENOG4105DAY polysaccharide export protein PsyrB_16690 ENOG4108UZX fmn reductase PsyrB_16705 ENOG4108M0I Transcriptional regulator PsyrB_16725 ENOG4105CRW Short chain fatty acid transporter PsyrB_16730 ENOG4105KAC Antibiotic biosynthesis monooxygenase PsyrB_16735 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) PsyrB_16740 ENOG4105C5I Dehydrogenase PsyrB_16745 ENOG4107VXM glycerophosphoryl diester phosphodiesterase PsyrB_16755 ENOG4105JIM Phosphatidylserine synthase PsyrB_16760 ENOG4105DQE DNA ligase PsyrB_16765 ENOG4105FDF Could be involved in DNA repair (By similarity) PsyrB_16775 ENOG4107SM7 Transcriptional regulator PsyrB_16800 ENOG4105D65 subunit l PsyrB_16805 ENOG4108ZE9 Monovalent cation H antiporter subunit C PsyrB_16810 ENOG4107R4Z monovalent cation h antiporter subunit d PsyrB_16815 ENOG4107R4Z monovalent cation h antiporter subunit d PsyrB_16825 ENOG4105W4C monovalent cation H antiporter subunit F PsyrB_16830 ENOG4105KJM monovalent cation h antiporter subunit g PsyrB_16850 ENOG4108W2P Methyl-accepting chemotaxis PsyrB_16855 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters PsyrB_16860 ENOG4108HWV )-transporter PsyrB_16865 ENOG4105C2J ABC transporter PsyrB_16880 ENOG4105D9R oxidoreductase PsyrB_16885 ENOG4105F0H myo-inositol catabolism protein PsyrB_16895 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) PsyrB_16905 ENOG4105C26 Dehydrogenase PsyrB_16910 ENOG4105DH8 myo-inositol catabolism PsyrB_16920 ENOG4105D7K pfkb domain protein PsyrB_16925 ENOG4108PSC Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity) PsyrB_16930 ENOG4107UXM Membrane PsyrB_16935 ENOG4105DZQ phospholipase D Transphosphatidylase PsyrB_16940 ENOG4105X23 Endonuclease Exonuclease phosphatase PsyrB_16950 ENOG4107RHB Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity) PsyrB_16965 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) PsyrB_16970 ENOG4106AIJ Cell Division PsyrB_16985 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) PsyrB_16995 ENOG4105CHU acetyl-coa acetyltransferase PsyrB_17000 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase PsyrB_17010 ENOG41081QV Universal stress protein PsyrB_17015 ENOG4105C5H ABC transporter PsyrB_17020 ENOG4107SC1 transglycosylase PsyrB_17025 ENOG4105QVC MOSC domain-containing protein PsyrB_17040 ENOG4105WH1 Two component transcriptional regulator luxr family PsyrB_17045 ENOG4107TE5 Lipid kinase PsyrB_17050 ENOG4105D3Q Sugar transferase PsyrB_17055 ENOG4105CJT Mannose-1-phosphate guanylyltransferase PsyrB_17100 ENOG4105CJR Integral membrane protein (MviN PsyrB_17105 ENOG4105DUM transcriptional regulator, lysR family PsyrB_17145 ENOG4105DJ2 Major Facilitator Superfamily PsyrB_17160 ENOG4105ERH Fumarylacetoacetate hydrolase PsyrB_17165 ENOG4105F1J Homogentisate 1,2-dioxygenase PsyrB_17180 ENOG4105BZU Histidine kinase PsyrB_17190 ENOG4105CQB FAD linked oxidase domain protein PsyrB_17195 ENOG4105EU8 FAD linked oxidase domain protein PsyrB_17200 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) PsyrB_17205 ENOG4108ZJF Glcg protein PsyrB_17215 ENOG4105DDV Transcriptional regulator (LacI family PsyrB_17220 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family PsyrB_17225 ENOG4105C6Z Gluconate PsyrB_17255 ENOG4108R6G acetyltransferase PsyrB_17270 ENOG41064MX Tetr family transcriptional regulator PsyrB_17300 ENOG4105CH6 catalase PsyrB_17310 ENOG4105CQZ Histidine kinase PsyrB_17320 ENOG4105F04 LysR family Transcriptional regulator PsyrB_17330 ENOG4105JAB phenazine biosynthesis protein, phzf family PsyrB_17335 ENOG4106UW1 Major Facilitator superfamily PsyrB_17345 ENOG4105D6Z AFG1 family ATPase PsyrB_17350 ENOG4105CHH sulfate transporter PsyrB_17360 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) PsyrB_17375 ENOG410650H (LipO)protein PsyrB_17380 ENOG4105DBE peroxidase PsyrB_17390 ENOG4105EQW The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) PsyrB_17395 ENOG4108S1C Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) PsyrB_17425 ENOG4105DSW Fusaric acid resistance protein PsyrB_17435 ENOG4105Y49 secretion protein, HlyD family PsyrB_17445 ENOG4105EYW Ion transport protein PsyrB_17450 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein PsyrB_17460 ENOG4108M1T Cytochrome c-type biogenesis protein PsyrB_17465 ENOG4105KWW Biogenesis protein PsyrB_17475 ENOG4105DA4 cytochrome c-type biogenesis protein PsyrB_17480 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) PsyrB_17490 ENOG41060IM Heme exporter protein PsyrB_17495 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) PsyrB_17500 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) PsyrB_17510 ENOG4105D00 flagellar biosynthetic protein flhB PsyrB_17515 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) PsyrB_17520 ENOG4105EXG Transcriptional regulator PsyrB_17530 ENOG4105KME endoribonuclease L-psp PsyrB_17535 ENOG4105MWK D-amino acid dehydrogenase, small subunit PsyrB_17540 ENOG4108Z7F N-acetyltransferase PsyrB_17550 ENOG4105EZ6 Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity) PsyrB_17555 ENOG4107QM5 aconitate hydratase PsyrB_17565 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor PsyrB_17610 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i PsyrB_17625 ENOG4105D6P C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity) PsyrB_17640 ENOG4105C58 cytochrome c oxidase accessory protein ccog PsyrB_17650 ENOG4105C59 p-type ATPase PsyrB_17665 ENOG4105D4P Coproporphyrinogen iii oxidase PsyrB_17680 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) PsyrB_17690 ENOG4108V3W Chemotaxis protein, CheW PsyrB_17700 ENOG4107QJE Chromosome Partitioning Protein PsyrB_17705 ENOG4106VK6 Flagellar motor protein PsyrB_17710 ENOG4105E14 MotA TolQ exbB proton channel PsyrB_17715 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) PsyrB_17720 ENOG4105CBS Chea signal transduction histidine kinase PsyrB_17725 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) PsyrB_17730 ENOG4108VYJ response regulator receiver protein PsyrB_17735 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) PsyrB_17745 ENOG4105FZW flagellar biosynthesis regulator FlhF PsyrB_17750 ENOG4105D7B Flagellar biosynthesis protein flha PsyrB_17755 ENOG4105D00 flagellar biosynthetic protein flhB PsyrB_17760 ENOG4105D19 Role in flagellar biosynthesis (By similarity) PsyrB_17765 ENOG4105VS8 Flagellar biosynthetic protein fliq PsyrB_17770 ENOG4105CN7 Flagellar biosynthetic protein FliP PsyrB_17775 ENOG4105VTB flagellar biosynthesis protein fliO PsyrB_17780 ENOG4105DD5 Flagellar motor switch protein PsyrB_17785 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) PsyrB_17810 ENOG4108KXV response regulator PsyrB_17825 ENOG4108JIR Flagellum-specific ATP synthase PsyrB_17835 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) PsyrB_17840 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) PsyrB_17845 ENOG4105VQ0 flagellar hook-basal body complex protein fliE PsyrB_17850 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_17855 ENOG4105BZU Histidine kinase PsyrB_17860 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_17870 ENOG4105MQ3 flagellar protein FliS PsyrB_17875 ENOG4105DTS flagellar hook-associated PsyrB_17880 ENOG41063QE flagellar protein FlaG PsyrB_17885 ENOG4105I03 Flagellin PsyrB_17890 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) PsyrB_17915 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj PsyrB_17920 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) PsyrB_17925 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) PsyrB_17930 ENOG4105CGA flagellar basal-body rod protein FlgG PsyrB_17935 ENOG4108KPB Flagellar basal-body rod protein FlgF PsyrB_17945 ENOG4105BZE flagellar hook protein, FlgE PsyrB_17950 ENOG4105BZE flagellar hook protein, FlgE PsyrB_17955 ENOG410822I Flagellar hook capping protein PsyrB_17960 ENOG4108ZC9 flagellar basal-body rod protein flgc PsyrB_17965 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) PsyrB_17975 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) PsyrB_17980 ENOG4105DND Transcriptional regulator PsyrB_17985 ENOG4105BZU Histidine kinase PsyrB_17990 ENOG4107R88 Chemotaxis protein (CheV) PsyrB_18010 ENOG4106825 Type iv pilus assembly PsyrB_18015 ENOG4108ISG Major Facilitator PsyrB_18045 ENOG4106MWK domain protein PsyrB_18050 ENOG4105EWT decarboxylase family PsyrB_18060 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase PsyrB_18065 ENOG4105CSP Major Facilitator Superfamily PsyrB_18085 ENOG4105BZU Histidine kinase PsyrB_18120 ENOG4105XJC Two component transcriptional regulator (Winged helix family PsyrB_18125 ENOG4105DHQ Histidine kinase PsyrB_18130 ENOG4105CJP fad dependent oxidoreductase PsyrB_18135 ENOG4105C26 Dehydrogenase PsyrB_18140 ENOG4108JPW Aminotransferase PsyrB_18145 ENOG4105E32 cytoplasmic protein PsyrB_18160 ENOG4105ETT transcriptional Regulator, LysR family PsyrB_18165 ENOG4105EJQ L-serine dehydratase PsyrB_18170 ENOG4105CH2 amidohydrolase PsyrB_18175 ENOG4105C26 Dehydrogenase PsyrB_18190 ENOG4105E2A Dehydrogenase PsyrB_18205 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease PsyrB_18210 ENOG4105CQZ Histidine kinase PsyrB_18220 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_18245 ENOG4108W6C Dehydrogenase PsyrB_18250 ENOG4105CB2 alcohol dehydrogenase PsyrB_18255 ENOG4108W6C Dehydrogenase PsyrB_18260 ENOG4105CYX Short-chain dehydrogenase reductase Sdr PsyrB_18265 ENOG4105CF7 AraC family transcriptional regulator PsyrB_18270 ENOG4105EG6 Saccharopine dehydrogenase PsyrB_18280 ENOG4105CYX Short-chain dehydrogenase reductase Sdr PsyrB_18285 ENOG4105CF7 AraC family transcriptional regulator PsyrB_18300 ENOG4105EGS Mechanosensitive ion channel PsyrB_18325 ENOG4105CJW magnesium transporter PsyrB_18355 ENOG4105CFH Aspartokinase PsyrB_18360 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) PsyrB_18365 ENOG4105C5W Aldolase PsyrB_18370 ENOG410908U Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) PsyrB_18385 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) PsyrB_18390 ENOG4105C26 Dehydrogenase PsyrB_18395 ENOG4105F4X arginine PsyrB_18400 ENOG4108T2Z Arginine PsyrB_18405 ENOG4105C8Y Acetylornithine aminotransferase PsyrB_18410 ENOG4105ECQ AraC Family Transcriptional Regulator PsyrB_18415 ENOG4108JEH abc transporter atp-binding protein PsyrB_18430 ENOG4105DSP amino acid AbC transporter PsyrB_18435 ENOG4105E89 ABC transporter PsyrB_18440 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) PsyrB_18450 ENOG4108JU8 Transcriptional regulator PsyrB_18455 ENOG4105MIR Phenylalanine 4-monooxygenase PsyrB_18460 ENOG41090A4 Pterin carbinolamine dehydratase PsyrB_18475 ENOG4108YZN class I peptide chain release factor PsyrB_18480 ENOG4105C85 amino acid PsyrB_18485 ENOG4105FE9 pseudouridine synthase PsyrB_18495 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) PsyrB_18505 ENOG4107RTD sua5 ycio yrdc ywlc family protein PsyrB_18510 ENOG4105DB7 PHP domain protein PsyrB_18515 ENOG4107835 probably involved in intracellular septation (By similarity) PsyrB_18520 ENOG4105K9H YciI-like protein PsyrB_18525 ENOG4105E3W Two component transcriptional regulator (Winged helix family PsyrB_18535 ENOG4105DHQ Histidine kinase PsyrB_18540 ENOG41069NU Nitroreductase PsyrB_18545 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) PsyrB_18565 ENOG4105E2Y ABC, transporter PsyrB_18570 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component PsyrB_18575 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) PsyrB_18580 ENOG4106KR7 LysR family Transcriptional regulator PsyrB_18585 ENOG4108T2C cysteine dioxygenase type I PsyrB_18595 ENOG4105GVF (ABC) transporter PsyrB_18600 ENOG4105FDT acyl-CoA dehydrogenase PsyrB_18605 ENOG4105CC0 LysR family Transcriptional regulator PsyrB_18610 ENOG4105C2I pirin domain protein PsyrB_18640 ENOG4108ZGC gaf domain protein PsyrB_18650 ENOG4105BZU Histidine kinase PsyrB_18655 ENOG4108MGY Histidine kinase PsyrB_18660 ENOG4108V06 Glutathione peroxidase PsyrB_18665 ENOG4105E0X reductase PsyrB_18670 ENOG4105CHM Aminotransferase PsyrB_18675 ENOG4105D0M Protease HtpX homolog PsyrB_18680 ENOG4105FQ6 thiopurine methyltransferase PsyrB_18685 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b PsyrB_18700 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase PsyrB_18720 ENOG4105K56 Transcriptional regulator PsyrB_18725 ENOG4108ZHJ Organic hydroperoxide resistance protein PsyrB_18730 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) PsyrB_18755 ENOG4105C44 Serine transporter PsyrB_18760 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen PsyrB_18770 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein PsyrB_18780 ENOG4105ESV Glycosyl transferase, family 4 PsyrB_18790 ENOG4105CY0 Metallo-Beta-Lactamase PsyrB_18800 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) PsyrB_18805 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) PsyrB_18810 ENOG4105CAT Cytidine monophosphate kinase PsyrB_18815 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase PsyrB_18820 ENOG4105CQC Prephenate dehydratase PsyrB_18825 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) PsyrB_18830 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) PsyrB_18840 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) PsyrB_18845 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) PsyrB_18850 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) PsyrB_18855 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) PsyrB_18860 ENOG4105UBK short-chain dehydrogenase reductase PsyrB_18865 ENOG4105BZU Histidine kinase PsyrB_18875 ENOG4105BZU Histidine kinase PsyrB_18890 ENOG4105C72 UPF0176 protein PsyrB_18895 ENOG4105M85 Bola protein PsyrB_18905 ENOG4105C9Q fumarate hydratase class II PsyrB_18915 ENOG4105QYV Membrane PsyrB_18930 ENOG4105CGY Dna recombination protein PsyrB_18945 ENOG4105ISI outer membrane protein, OMPP1 FadL TodX family PsyrB_18965 ENOG4105GN9 Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) PsyrB_18970 ENOG4108TGR phosphatase PsyrB_18975 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) PsyrB_18980 ENOG4108YZT Adenosylcobinamide kinase PsyrB_18985 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) PsyrB_18990 ENOG4105EFT decarboxylase PsyrB_18995 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) PsyrB_19000 ENOG4105E7Q Cob(II)yrinic acid a,c-diamide reductase PsyrB_19005 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) PsyrB_19010 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase PsyrB_19020 ENOG4105K4H Nlp p60 protein PsyrB_19030 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) PsyrB_19035 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) PsyrB_19040 ENOG4105C02 permease PsyrB_19050 ENOG4105CXB phosphoribosylaminoimidazole synthetase PsyrB_19055 ENOG4108V3E phosphoribosylglycinamide formyltransferase PsyrB_19075 ENOG4105DXN mazG family PsyrB_19080 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) PsyrB_19085 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) PsyrB_19090 ENOG4105C6T cysteine synthase PsyrB_19095 ENOG4105BZU Histidine kinase PsyrB_19110 ENOG4105K63 Thioredoxin PsyrB_19115 ENOG4105K89 arsenate reductase PsyrB_19120 ENOG4105CS1 NAD(P)H quinone oxidoreductase PsyrB_19125 ENOG4108R3E Dna-3-methyladenine glycosylase i PsyrB_19130 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) PsyrB_19135 ENOG4105GPY SprT protein PsyrB_19140 ENOG4105CK2 sodium dicarboxylate symporter PsyrB_19150 ENOG4105XJC Two component transcriptional regulator (Winged helix family PsyrB_19185 ENOG4105JJR Histidine kinase PsyrB_19190 ENOG4107EXC regulatoR PsyrB_19195 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) PsyrB_19200 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) PsyrB_19210 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) PsyrB_19220 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 PsyrB_19260 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor PsyrB_19275 ENOG4108US0 Transcription regulator that can specifically activate or repress expression of target genes (By similarity) PsyrB_19280 ENOG4105C9U ATP-dependent DNA helicase RecQ PsyrB_19290 ENOG4105WD1 Membrane PsyrB_19295 ENOG4105CSR polyphosphate kinase 2 PsyrB_19300 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) PsyrB_19305 ENOG4108I0Y (ABC) transporter PsyrB_19325 ENOG4105CAQ asparagine synthetase PsyrB_19330 ENOG4107RRY Cyanophycin synthetase PsyrB_19335 ENOG4105DER m42 family PsyrB_19340 ENOG4106851 UPF0270 protein PsyrB_19345 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) PsyrB_19370 ENOG4107QN1 sodium solute PsyrB_19375 ENOG41062QD Membrane PsyrB_19395 ENOG410903C (LipO)protein PsyrB_19410 ENOG4105BZU Histidine kinase PsyrB_19430 ENOG4105CSH Transporter PsyrB_19445 ENOG4105D8V Glucose sorbosone dehydrogenase PsyrB_19455 ENOG4105BZU Histidine kinase PsyrB_19460 ENOG4105BZU Histidine kinase PsyrB_19465 ENOG4107R6F Alpha Beta Hydrolase Fold protein PsyrB_19470 ENOG4108Z6B deaminase PsyrB_19490 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) PsyrB_19495 ENOG4107U9T Pfam:Ribonuclease_BN PsyrB_19500 ENOG41067RQ csbd family PsyrB_19515 ENOG4107ZXU DSBA oxidoreductase PsyrB_19520 ENOG4105QNR S1 RNA binding domain protein PsyrB_19550 ENOG4105C1J atp-dependent rna helicase PsyrB_19555 ENOG410804D Sensor Signal Transduction Histidine Kinase PsyrB_19560 ENOG4105E3W Two component transcriptional regulator (Winged helix family PsyrB_19580 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF PsyrB_19590 ENOG4105ENX hydrolase PsyrB_19595 ENOG4107RTG Major Facilitator superfamily PsyrB_19600 ENOG4105EQ2 LysR family Transcriptional regulator PsyrB_19610 ENOG4105CUY Mechanosensitive ion channel PsyrB_19630 ENOG4105F2I Transposase PsyrB_19725 ENOG4105D70 Integrase catalytic subunit PsyrB_19730 ENOG4105F5W AtP-binding protein PsyrB_19750 ENOG4105CAU Arsenical resistance protein, ArsH PsyrB_19765 ENOG41082YX Transcriptional regulator, arsr family PsyrB_19810 ENOG4105CC0 LysR family Transcriptional regulator PsyrB_19815 ENOG4105CHR reductase PsyrB_19860 ENOG4106PGW Short-chain dehydrogenase reductase Sdr PsyrB_19865 ENOG4105EMK carboxylate amino acid amine transporter PsyrB_19875 ENOG4107F2M hemolysin-type calcium-binding region PsyrB_19890 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) PsyrB_19895 ENOG4105BZ1 (ABC) transporter PsyrB_19900 ENOG4105BZ1 (ABC) transporter PsyrB_19920 ENOG4105CQ7 ATP-dependent helicase PsyrB_19935 ENOG4105CEY Amp-dependent synthetase and ligase PsyrB_19940 ENOG4105CEY Amp-dependent synthetase and ligase PsyrB_19945 ENOG4108F01 MaoC domain protein PsyrB_19950 ENOG4108NR7 pectate lyase PsyrB_19965 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) PsyrB_19970 ENOG4105BZU Histidine kinase PsyrB_19980 ENOG4105CP9 extracellular ligand-binding receptor PsyrB_19985 ENOG4105C32 Amino acid ABC transporter (Permease) PsyrB_19990 ENOG4105CF8 branched-chain amino acid ABC transporter, permease PsyrB_19995 ENOG4105C0Z ABC transporter PsyrB_20000 ENOG4108IV0 ABC, transporter PsyrB_20010 ENOG4105DZ0 fad dependent oxidoreductase PsyrB_20025 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) PsyrB_20040 ENOG4105DVT helicase PsyrB_20050 ENOG4105DRB nucleoside-specific channel-forming protein PsyrB_20075 ENOG4105K5B UPF0225 protein PsyrB_20110 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving PsyrB_20115 ENOG4105CUJ penicillin amidase PsyrB_20120 ENOG4107T0X DNA ligase PsyrB_20125 ENOG4107T0X DNA ligase PsyrB_20130 ENOG4105E89 ABC transporter PsyrB_20135 ENOG4105DSP amino acid AbC transporter PsyrB_20140 ENOG4106YG3 ABC transporter PsyrB_20150 ENOG4108JEH abc transporter atp-binding protein PsyrB_20155 ENOG4107QRT dEAD DEAH box helicase PsyrB_20170 ENOG4105DHP deoxycytidine triphosphate deaminase PsyrB_20185 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) PsyrB_20190 ENOG4108R3D Electron transport complex PsyrB_20195 ENOG4105CSM endonuclease III PsyrB_20205 ENOG4108WQH regulatoR PsyrB_20215 ENOG4105CDH Citrulline--aspartate ligase PsyrB_20225 ENOG4105EKE dihydroorotase PsyrB_20230 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) PsyrB_20235 ENOG4108UQY Iron-storage protein PsyrB_20240 ENOG4105M2J Glutaredoxin PsyrB_20245 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) PsyrB_20255 ENOG4105DBV ornithine carbamoyltransferase PsyrB_20265 ENOG4108Z66 YbaK ebsC protein PsyrB_20270 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) PsyrB_20275 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) PsyrB_20280 ENOG4105E98 transcriptional regulator DeoR family PsyrB_20290 ENOG4107RP9 extracellular solute-binding protein, family 3 PsyrB_20295 ENOG4105EAD ABC transporter PsyrB_20300 ENOG4105DRP amino acid AbC transporter PsyrB_20305 ENOG4105CDA abc transporter atp-binding protein PsyrB_20310 ENOG4105CQZ Histidine kinase PsyrB_20315 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_20325 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) PsyrB_20330 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) PsyrB_20335 ENOG4105DZ2 Transcriptional regulator PsyrB_20345 ENOG4105CPF Cell wall formation (By similarity) PsyrB_20350 ENOG4105NRA 50s ribosomal protein l31 type b PsyrB_20380 ENOG4105NTW Transcriptional regulator PsyrB_20385 ENOG4105Q26 Siderophore-interacting protein PsyrB_20395 ENOG4105VYA Uncharacterized conserved protein (DUF2132) PsyrB_20400 ENOG4105DZG Dehydrogenase PsyrB_20415 ENOG4105CKI cobalamin synthesis protein PsyrB_20425 ENOG4105CHR reductase PsyrB_20430 ENOG4105H9W Short-chain dehydrogenase reductase Sdr PsyrB_20450 ENOG4105FDP GntR family transcriptional regulator PsyrB_20465 ENOG4105BZU Histidine kinase PsyrB_20475 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) PsyrB_20485 ENOG4105DA6 Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) PsyrB_20490 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) PsyrB_20495 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) PsyrB_20500 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) PsyrB_20505 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) PsyrB_20510 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) PsyrB_20520 ENOG4105C3F Signal peptidase i PsyrB_20525 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) PsyrB_20530 ENOG4105C0H protease PsyrB_20535 ENOG4105VQK sigma E regulatory protein, MucB RseB PsyrB_20540 ENOG41069E1 anti sigma-E protein RseA PsyrB_20545 ENOG4105EMN RNA polymerase sigma factor PsyrB_20550 ENOG4108IYU L-aspartate oxidase PsyrB_20555 ENOG4105Y75 tpr repeat protein PsyrB_20560 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) PsyrB_20570 ENOG4105DHQ Histidine kinase PsyrB_20600 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) PsyrB_20635 ENOG4105EIG urea carboxylase-associated protein 1 PsyrB_20645 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase PsyrB_20650 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit PsyrB_20665 ENOG4105I08 Pseudouridine synthase PsyrB_20670 ENOG4108YI3 3-hydroxyacyl-CoA-acyl carrier protein transferase PsyrB_20700 ENOG4105C0A alcohol dehydrogenase PsyrB_20730 ENOG4107QK4 glycoside hydrolase, family 3 domain protein PsyrB_20740 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_20745 ENOG4105CQZ Histidine kinase PsyrB_20750 ENOG4105F7F Chaperone PsyrB_20760 ENOG4105CSH Transporter PsyrB_20805 ENOG4105C1P efflux transporter, rnd family, mfp subunit PsyrB_20810 ENOG4105BZS acriflavin resistance protein PsyrB_20815 ENOG4105ENJ RND efflux system, outer membrane lipoprotein PsyrB_20820 ENOG4105CSH Transporter PsyrB_20825 ENOG4105CHU acetyl-coa acetyltransferase PsyrB_20840 ENOG4107HP6 Transcriptional regulator PsyrB_20850 ENOG4105CJ3 phosphate transporter PsyrB_20870 ENOG4105CJB Exodeoxyribonuclease I PsyrB_20930 ENOG4105C7R Atpase associated with various cellular activities aaa_3 PsyrB_20950 ENOG4105CA9 Pyruvate kinase PsyrB_20955 ENOG4107QK7 reductase PsyrB_20960 ENOG4107GFK fumarate PsyrB_21030 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) PsyrB_21070 ENOG4105F27 Major Facilitator PsyrB_21075 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase PsyrB_21090 ENOG4105CGD Nad-dependent epimerase dehydratase PsyrB_21095 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) PsyrB_21105 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) PsyrB_21110 ENOG4105BZU Histidine kinase PsyrB_21145 ENOG4105FQR PH-inducible protein involved in stress response PsyrB_21155 ENOG4105DHQ Histidine kinase PsyrB_21170 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) PsyrB_21175 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) PsyrB_21185 ENOG4105FS0 cytoplasmic membrane protein PsyrB_21190 ENOG4105CHR reductase PsyrB_21200 ENOG41080UX Methyltransferase PsyrB_21245 ENOG4105D64 Mechanosensitive ion channel PsyrB_21250 ENOG4108VPT UPF0234 protein PsyrB_21255 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) PsyrB_21260 ENOG4105BZU Histidine kinase PsyrB_21265 ENOG4108WBT adenosyltransferase PsyrB_21270 ENOG4105M6F mutator MutT protein PsyrB_21280 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) PsyrB_21285 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving PsyrB_21295 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) PsyrB_21300 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) PsyrB_21305 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) PsyrB_21310 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) PsyrB_21315 ENOG4105CPF Cell wall formation (By similarity) PsyrB_21320 ENOG4105DFU Cell wall formation (By similarity) PsyrB_21325 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) PsyrB_21330 ENOG4105CNI cell division protein FtsW PsyrB_21335 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) PsyrB_21340 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) PsyrB_21345 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) PsyrB_21350 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) PsyrB_21355 ENOG4105CJN penicillin-binding protein PsyrB_21365 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) PsyrB_21370 ENOG4108V6E Cell division protein mraZ PsyrB_21380 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) PsyrB_21385 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) PsyrB_21390 ENOG41082RQ UPF0102 protein PsyrB_21395 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) PsyrB_21400 ENOG4105W4M Transport-associated protein PsyrB_21405 ENOG4105KB2 stringent starvation protein b PsyrB_21410 ENOG4107MKT Stringent starvation protein a PsyrB_21415 ENOG4108UJD 30S ribosomal protein S9 PsyrB_21420 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) PsyrB_21430 ENOG4105D6Z AFG1 family ATPase PsyrB_21435 ENOG4105C31 Tryptophanyl-tRNA synthetase PsyrB_21450 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) PsyrB_21455 ENOG4105C11 sulfate adenylyltransferase), subunit 2 PsyrB_21460 ENOG4107QNR UPF0135 protein PsyrB_21465 ENOG4105C0H protease PsyrB_21470 ENOG4105CIH Imidazole acetol-phosphate transaminase PsyrB_21475 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) PsyrB_21480 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) PsyrB_21485 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) PsyrB_21505 ENOG4107PE3 Mammalian cell entry related domain protein PsyrB_21510 ENOG4105CY3 ABC transporter, permease PsyrB_21515 ENOG4105DHJ ABC, transporter PsyrB_21520 ENOG4105C2X Arabinose 5-phosphate isomerase PsyrB_21525 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase PsyrB_21535 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA PsyrB_21540 ENOG4108IUZ ABC transporter PsyrB_21545 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) PsyrB_21550 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA PsyrB_21555 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN PsyrB_21560 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) PsyrB_21565 ENOG41080Z8 PHOSPHOCARRIER protein PsyrB_21575 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) PsyrB_21585 ENOG4105CMS peptidase U62, modulator of DNA gyrase PsyrB_21590 ENOG4105N42 UPF0307 protein PsyrB_21595 ENOG4105D1U peptidase U62 modulator of DNA gyrase PsyrB_21610 ENOG4105C03 ribonuclease PsyrB_21615 ENOG4108Z03 MAF-like protein PsyrB_21625 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) PsyrB_21630 ENOG4105DFF Rod shape-determining protein mreb PsyrB_21635 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) PsyrB_21640 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) PsyrB_21645 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) PsyrB_21650 ENOG4105K6T rare lipoprotein A PsyrB_21660 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase PsyrB_21675 ENOG4105DR4 Methyltransferase PsyrB_21690 ENOG4105W4M Transport-associated protein PsyrB_21695 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) PsyrB_21700 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) PsyrB_21710 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) PsyrB_21715 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) PsyrB_21720 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) PsyrB_21725 ENOG4105CHV Transcription elongation factor NusA PsyrB_21730 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) PsyrB_21745 ENOG4105NTZ Preprotein translocase subunit SecG PsyrB_21750 ENOG4105CP7 Triose-phosphate isomerase PsyrB_21755 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) PsyrB_21760 ENOG4105EEI dihydropteroate synthase PsyrB_21765 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) PsyrB_21770 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) PsyrB_21775 ENOG4105HBR Rna-binding protein PsyrB_21780 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) PsyrB_21785 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain PsyrB_21790 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain PsyrB_21800 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) PsyrB_21805 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) PsyrB_21815 ENOG4105CFG Acts as a chaperone (By similarity) PsyrB_21820 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ PsyrB_21825 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) PsyrB_21830 ENOG41090R7 Ferric uptake PsyrB_21835 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) PsyrB_21840 ENOG4105VDB UPF0125 protein PsyrB_21845 ENOG4108Z1B Cyclase dehydrase PsyrB_21850 ENOG4105C8J )-transporter PsyrB_21855 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) PsyrB_21875 ENOG4105BZU Histidine kinase PsyrB_21885 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) PsyrB_21895 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) PsyrB_21915 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component PsyrB_21920 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component PsyrB_21930 ENOG4107WYG Transcriptional regulator, luxr family PsyrB_21960 ENOG4107TSN permease PsyrB_21980 ENOG4105CTX dehydratase PsyrB_21985 ENOG4105DJB Major Facilitator Superfamily PsyrB_21990 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase PsyrB_21995 ENOG41073TP transcriptional regulator PsyrB_22000 ENOG4105CQ0 ABC transporter PsyrB_22010 ENOG4105TX3 Histidine kinase PsyrB_22025 ENOG4105DEF Extracellular solute-binding protein, family 5 PsyrB_22030 ENOG4105DEF Extracellular solute-binding protein, family 5 PsyrB_22035 ENOG4105DEF Extracellular solute-binding protein, family 5 PsyrB_22040 ENOG4105J5J Outer membrane porin PsyrB_22045 ENOG4105DEF Extracellular solute-binding protein, family 5 PsyrB_22050 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component PsyrB_22055 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component PsyrB_22060 ENOG4105C3U ABC transporter PsyrB_22065 ENOG4108JQ7 (ABC) transporter PsyrB_22070 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) PsyrB_22090 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) PsyrB_22095 ENOG4108IJ8 ABC transporter PsyrB_22100 ENOG4105E90 ABC transporter PsyrB_22105 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system PsyrB_22110 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component PsyrB_22115 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) PsyrB_22120 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) PsyrB_22125 ENOG4108V1T peptidylprolyl cis-trans isomerase PsyrB_22135 ENOG4108TEB UPF0114 protein PsyrB_22145 ENOG4105DAN ATP-dependent protease PsyrB_22165 ENOG4108RRZ Transcription elongation factor GreB PsyrB_22170 ENOG4105C5H ABC transporter PsyrB_22175 ENOG4105BZU Histidine kinase PsyrB_22200 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) PsyrB_22205 ENOG4105CKI cobalamin synthesis protein PsyrB_22210 ENOG4105VCD cytoplasmic protein PsyrB_22215 ENOG4105D22 carbon starvation protein PsyrB_22225 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) PsyrB_22230 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) PsyrB_22235 ENOG4105DP0 ferredoxin-NADP reductase PsyrB_22240 ENOG4105VJY transcriptional regulator PsyrB_22245 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) PsyrB_22255 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii PsyrB_22260 ENOG4105C4M (Ubiquinol oxidase) subunit I PsyrB_22265 ENOG4105C7W Xanthine dehydrogenase PsyrB_22270 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding PsyrB_22275 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit PsyrB_22280 ENOG4105C7N Xanthine uracil vitamin C permease PsyrB_22285 ENOG4107R9T Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity) PsyrB_22295 ENOG4105CGZ zinc metallopeptidase PsyrB_22310 ENOG4105C29 acyl-CoA thioesterase PsyrB_22315 ENOG4108YYQ gCN5-related N-acetyltransferase PsyrB_22320 ENOG4105DGU Histone deacetylase PsyrB_22325 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase PsyrB_22330 ENOG4105C1J atp-dependent rna helicase PsyrB_22335 ENOG4105FDR Membrane PsyrB_22345 ENOG4105DVT helicase PsyrB_22355 ENOG4105G4C Periplasmic ligand-binding sensor protein PsyrB_22380 ENOG4105JQZ Methyltransferase PsyrB_22400 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase PsyrB_22410 ENOG4107SQU synthase PsyrB_22415 ENOG4107SQU synthase PsyrB_22420 ENOG4105CAQ asparagine synthetase PsyrB_22435 ENOG4105ETT transcriptional Regulator, LysR family PsyrB_22440 ENOG4105CQ7 ATP-dependent helicase PsyrB_22450 ENOG4105DXI Major Facilitator superfamily PsyrB_22455 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) PsyrB_22460 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) PsyrB_22470 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) PsyrB_22505 ENOG41076HS cation diffusion facilitator family transporter PsyrB_22520 ENOG4108XM1 transcriptional regulator AsnC family PsyrB_22525 ENOG4108R99 pseudouridine synthase PsyrB_22530 ENOG4105FYV Amp nucleosidase PsyrB_22535 ENOG4105CSU acyl-Coa dehydrogenase PsyrB_22540 ENOG4105BZU Histidine kinase PsyrB_22550 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) PsyrB_22555 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase PsyrB_22570 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) PsyrB_22575 ENOG4105C9A Phoh family PsyrB_22580 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) PsyrB_22585 ENOG4108JU5 Magnesium and cobalt efflux protein PsyrB_22590 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) PsyrB_22595 ENOG41080C8 DUF218 domain PsyrB_22605 ENOG4105C8T Leucyl-tRNA synthetase PsyrB_22625 ENOG4105CVE Lytic murein transglycosylase PsyrB_22630 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) PsyrB_22635 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) PsyrB_22645 ENOG4105DZ1 carboxypeptidase PsyrB_22650 ENOG4105K6T rare lipoprotein A PsyrB_22655 ENOG4105CVE Lytic murein transglycosylase PsyrB_22660 ENOG4105CNI cell division protein FtsW PsyrB_22665 ENOG4105CJN penicillin-binding protein PsyrB_22670 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) PsyrB_22680 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) PsyrB_22685 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) PsyrB_22690 ENOG4108RB4 3-methyladenine DNA glycosylase PsyrB_22695 ENOG4108KF1 Membrane PsyrB_22725 ENOG4105BZU Histidine kinase PsyrB_22735 ENOG4105PTV Nudix Hydrolase PsyrB_22740 ENOG4108ZJT translation initiation factor, Sui1 PsyrB_22745 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) PsyrB_22760 ENOG4107R73 Mate efflux family protein PsyrB_22765 ENOG4105DN3 alpha-2-macroglobulin domain protein PsyrB_22775 ENOG4108JQB penicillin-binding protein 1C PsyrB_22820 ENOG4105VK0 repeat-containing protein PsyrB_22830 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) PsyrB_22835 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) PsyrB_22840 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein PsyrB_22845 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase PsyrB_22850 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) PsyrB_22860 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) PsyrB_22865 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) PsyrB_22870 ENOG4105DC1 bifunctional purine biosynthesis protein purh PsyrB_22875 ENOG4105C12 Phosphoribosylglycinamide synthetase PsyrB_22880 ENOG4105BZU Histidine kinase PsyrB_22885 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein PsyrB_22915 ENOG4105DVK Precorrin-2 c20-methyltransferase PsyrB_22920 ENOG41081F0 Precorrin-8x methylmutase PsyrB_22925 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) PsyrB_22930 ENOG4105CX4 Precorrin-6y C5,15-methyltransferase PsyrB_22935 ENOG4105EE8 May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity) PsyrB_22970 ENOG41083Z3 extracellular ligand-binding receptor PsyrB_22975 ENOG4105C32 Amino acid ABC transporter (Permease) PsyrB_22985 ENOG4105C0Z ABC transporter PsyrB_22990 ENOG4108IV0 ABC, transporter PsyrB_22995 ENOG4108M9X Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) PsyrB_23000 ENOG4108YZ9 Urea amidohydrolase subunit gamma PsyrB_23015 ENOG4105KI2 Urea amidohydrolase subunit beta PsyrB_23020 ENOG4105CQM Urea amidohydrolase subunit alpha PsyrB_23025 ENOG4105K63 Thioredoxin PsyrB_23035 ENOG4105BZU Histidine kinase PsyrB_23040 ENOG4105DVC DnaJ domain protein PsyrB_23045 ENOG4105R8A Heat shock protein PsyrB_23055 ENOG4105VIF phosphate starvation-inducible protein PsyrB_23060 ENOG4108IPJ Membrane PsyrB_23080 ENOG41066T0 asmA family PsyrB_23085 ENOG4105EJ2 Transcriptional regulator PsyrB_23090 ENOG4105MMR Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity) PsyrB_23095 ENOG4105IY8 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) PsyrB_23100 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) PsyrB_23115 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) PsyrB_23120 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) PsyrB_23125 ENOG4107YIM Involved in the transcription termination process (By similarity) PsyrB_23130 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) PsyrB_23135 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) PsyrB_23145 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) PsyrB_23150 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) PsyrB_23160 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) PsyrB_23165 ENOG4107QR8 Thioredoxin PsyrB_23200 ENOG4105EIF outer membrane protein W PsyrB_23215 ENOG4105D8X mechanosensitive ion channel PsyrB_23225 ENOG4105ERH Fumarylacetoacetate hydrolase PsyrB_23230 ENOG4105WQ5 TonB family PsyrB_23240 ENOG4105SG9 biopolymer transport protein, ExbD PsyrB_23265 ENOG4108RVA ribokinase PsyrB_23270 ENOG4105EDR glucose galactose transporter PsyrB_23280 ENOG4107FB0 transcriptional regulator DeoR family PsyrB_23285 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) PsyrB_23295 ENOG4105BZU Histidine kinase PsyrB_23325 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) PsyrB_23330 ENOG4105D6F Phosphatase PsyrB_23340 ENOG4108IJG ABC transporter substrate-binding protein PsyrB_23345 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component PsyrB_23355 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) PsyrB_23360 ENOG4107T6V glycerophosphoryl diester phosphodiesterase PsyrB_23370 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) PsyrB_23375 ENOG4108UUM single-stranded DNA-binding protein PsyrB_23380 ENOG4107RDB Major Facilitator PsyrB_23385 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) PsyrB_23390 ENOG4108UWD Iron-storage protein PsyrB_23400 ENOG4108ZT0 50S ribosomal protein l17 PsyrB_23405 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) PsyrB_23410 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) PsyrB_23415 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) PsyrB_23420 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits PsyrB_23430 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) PsyrB_23435 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) PsyrB_23440 ENOG4105VPB 50S ribosomal protein L30 PsyrB_23445 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) PsyrB_23450 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) PsyrB_23455 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) PsyrB_23460 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) PsyrB_23465 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) PsyrB_23470 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits PsyrB_23475 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) PsyrB_23480 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) PsyrB_23485 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal PsyrB_23490 ENOG41083MP 50s ribosomal protein l29 PsyrB_23495 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) PsyrB_23500 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) PsyrB_23505 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) PsyrB_23510 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) PsyrB_23515 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity PsyrB_23520 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) PsyrB_23525 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) PsyrB_23530 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) PsyrB_23535 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) PsyrB_23540 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) PsyrB_23545 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) PsyrB_23550 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) PsyrB_23555 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) PsyrB_23565 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) PsyrB_23570 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) PsyrB_23585 ENOG4108VZM 50s ribosomal protein L10 PsyrB_23595 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) PsyrB_23600 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) PsyrB_23605 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) PsyrB_23610 ENOG4105PM1 preprotein translocase subunit SecE PsyrB_23640 ENOG4108194 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) PsyrB_23645 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase PsyrB_23680 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) PsyrB_23685 ENOG4105DR5 peptidase PsyrB_23690 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) PsyrB_23695 ENOG4108YX9 iron--sulfur cluster insertion protein erpA PsyrB_23700 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase PsyrB_23705 ENOG4108YXA Membrane PsyrB_23715 ENOG4105PDP Short chain dehydrogenase PsyrB_23720 ENOG4107YU2 histidine triad (hIT) protein PsyrB_23725 ENOG4108S0N Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity) PsyrB_23730 ENOG4105FDS Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) PsyrB_23735 ENOG4108UKZ OsmC family PsyrB_23740 ENOG4107RYR Transcriptional regulator, Crp Fnr family PsyrB_23750 ENOG4105DK0 Indole-3-glycerol phosphate synthase PsyrB_23755 ENOG4108I0Q anthranilate phosphoribosyltransferase PsyrB_23760 ENOG4105DDQ anthranilate synthase PsyrB_23775 ENOG4105NVB glycoside hydrolase, family 19 PsyrB_23795 ENOG4108T86 baseplate J family protein PsyrB_23800 ENOG4105WR6 Phage protein, GP46 PsyrB_23840 ENOG4105TKZ Tail Sheath PsyrB_23895 ENOG4108FHP Autotransporter beta-domain PsyrB_23900 ENOG4105DQ6 Transposase PsyrB_23905 ENOG4105CRQ synthase (Component I) PsyrB_23910 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) PsyrB_23915 ENOG4105DJV ribulose-phosphate 3-epimerase PsyrB_23925 ENOG4105F38 ABC transporter, permease PsyrB_23935 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) PsyrB_23940 ENOG4105WH1 Two component transcriptional regulator luxr family PsyrB_23945 ENOG4105ENE Histidine kinase PsyrB_23955 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) PsyrB_23960 ENOG4108S0S Nucleotidyl transferase PsyrB_23965 ENOG4105EHM Aminoglycoside phosphotransferase PsyrB_23970 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) PsyrB_23975 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) PsyrB_23980 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) PsyrB_23985 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) PsyrB_23990 ENOG4105NWN ApaG protein PsyrB_23995 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) PsyrB_24000 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) PsyrB_24005 ENOG4105CYN Serine protein kinase PsyrB_24010 ENOG4106AKX UPF0229 protein PsyrB_24015 ENOG4105ED1 spovr family PsyrB_24020 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate PsyrB_24025 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase PsyrB_24030 ENOG4107ZVW dihydroneopterin aldolase PsyrB_24035 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) PsyrB_24040 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) PsyrB_24045 ENOG4105VCC 30S ribosomal protein S21 PsyrB_24050 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) PsyrB_24060 ENOG4105BZU Histidine kinase PsyrB_24100 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) PsyrB_24130 ENOG4107QXP Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) PsyrB_24135 ENOG4105TMB Formate nitrite transporter PsyrB_24170 ENOG4108JQM Insulinase (Peptidase family M16) PsyrB_24175 ENOG4105JIE May be involved in the transport of PQQ or its precursor to the periplasm (By similarity) PsyrB_24180 ENOG41086XE Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity) PsyrB_24185 ENOG4106URE pyrroloquinoline quinone biosynthesis protein d PsyrB_24190 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E PsyrB_24210 ENOG4105CSU acyl-Coa dehydrogenase PsyrB_24215 ENOG4106TD9 Diguanylate cyclase PsyrB_24220 ENOG4105CSU acyl-Coa dehydrogenase PsyrB_24240 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) PsyrB_24245 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) PsyrB_24250 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) PsyrB_24255 ENOG4105MJ2 Competence protein PsyrB_24260 ENOG4105F4R Transcriptional regulator mode PsyrB_24270 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) PsyrB_24275 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) PsyrB_24280 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component PsyrB_24285 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component PsyrB_24300 ENOG4105DDV Transcriptional regulator (LacI family PsyrB_24305 ENOG4105E27 serine threonine protein kinase PsyrB_24310 ENOG4105FR1 rard protein PsyrB_24320 ENOG4107QP3 malate synthase g PsyrB_24335 ENOG41083X2 DNA polymerase III, epsilon subunit PsyrB_24360 ENOG4105ECQ AraC Family Transcriptional Regulator PsyrB_24375 ENOG4108IJ7 Glycine betaine PsyrB_24380 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) PsyrB_24410 ENOG4105E2A Dehydrogenase PsyrB_24450 ENOG4106HNH Acyl-transferase PsyrB_24460 ENOG4105DQ6 Transposase PsyrB_24475 ENOG4108U78 Glutathione S-transferase PsyrB_24490 ENOG4108S3W Anti-feci sigma factor, fecr PsyrB_24495 ENOG4108SF5 RNA Polymerase PsyrB_24500 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) PsyrB_24505 ENOG4105C26 Dehydrogenase PsyrB_24510 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) PsyrB_24515 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) PsyrB_24535 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) PsyrB_24540 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) PsyrB_24545 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) PsyrB_24555 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase PsyrB_24560 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) PsyrB_24565 ENOG4105CRP Part of the ABC transporter FtsEX involved in PsyrB_24570 ENOG4105CAK Cell division ATP-binding protein ftsE PsyrB_24575 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) PsyrB_24590 ENOG4106H78 methyltransferase PsyrB_24595 ENOG4105DNZ Alpha Beta Hydrolase PsyrB_24600 ENOG4105KHC sulfurtransferase PsyrB_24610 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) PsyrB_24615 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding PsyrB_24625 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) PsyrB_24630 ENOG4108HU6 Metal dependent phosphohydrolase PsyrB_24635 ENOG4108Z0Z intracellular protease Pfpi family PsyrB_24640 ENOG4105DR4 Methyltransferase PsyrB_24665 ENOG4105C0R drug resistance transporter emrb qaca subfamily PsyrB_24670 ENOG4105BZU Histidine kinase PsyrB_24675 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) PsyrB_24680 ENOG4105D6S protein involved in catabolism of external DNA PsyrB_24700 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) PsyrB_24705 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit PsyrB_24710 ENOG4105E03 chitinase PsyrB_24730 ENOG4105DF6 Fe-S oxidoreductase PsyrB_24760 ENOG4105D2N Aldolase PsyrB_24780 ENOG4105BZA Phosphoglycerate kinase PsyrB_24785 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase PsyrB_24790 ENOG4105CV1 Transketolase (EC 2.2.1.1) PsyrB_24800 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP PsyrB_24805 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) PsyrB_24820 ENOG4105GR3 Histidine kinase PsyrB_24850 ENOG4105CNA YD repeat protein PsyrB_24870 ENOG4105CNA YD repeat protein PsyrB_24895 ENOG4105J5J Outer membrane porin PsyrB_24910 ENOG4105EEQ Na H antiporter PsyrB_24925 ENOG4105CHR reductase PsyrB_24930 ENOG4105MVE transcriptional regulator PsyrB_24940 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) PsyrB_24965 ENOG4105CUX Signal transduction histidine kinase PsyrB_24970 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_24975 ENOG4105CPC Aldo Keto reductase PsyrB_24980 ENOG4105GVF (ABC) transporter PsyrB_24985 ENOG4105CPU Monooxygenase PsyrB_24995 ENOG4105C94 Transporter PsyrB_25000 ENOG4105CGP Urocanate hydratase PsyrB_25010 ENOG4108HQS Glycine betaine PsyrB_25015 ENOG4108IJ7 Glycine betaine PsyrB_25020 ENOG4105C84 Histidine ammonia-lyase PsyrB_25025 ENOG4105C84 Histidine ammonia-lyase PsyrB_25030 ENOG4105C85 amino acid PsyrB_25035 ENOG4105CI2 imidazolone-5-propionate hydrolase PsyrB_25050 ENOG4105W1Y Transcriptional regulator PsyrB_25065 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) PsyrB_25070 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) PsyrB_25075 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase PsyrB_25080 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) PsyrB_25095 ENOG4105E66 phosphoriboisomerase A PsyrB_25100 ENOG4108ZK4 sdia-regulated domain-containing protein PsyrB_25110 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase PsyrB_25115 ENOG4105CQB FAD linked oxidase domain protein PsyrB_25120 ENOG4108JQ1 Dehydrogenase PsyrB_25155 ENOG4105D38 putrescine abc transporter PsyrB_25160 ENOG4105F38 ABC transporter, permease PsyrB_25165 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) PsyrB_25170 ENOG4108HM4 ABC transporter PsyrB_25180 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) PsyrB_25185 ENOG4105CFQ glutamine synthetase PsyrB_25195 ENOG4105CFQ glutamine synthetase PsyrB_25220 ENOG4105F4R Transcriptional regulator mode PsyrB_25225 ENOG4105E2Y ABC, transporter PsyrB_25230 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component PsyrB_25235 ENOG4105GVF (ABC) transporter PsyrB_25240 ENOG4105D3R alkyl hydroperoxide reductase PsyrB_25245 ENOG4105EPF Outer membrane porin PsyrB_25255 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) PsyrB_25260 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) PsyrB_25265 ENOG4105VW4 glutaredoxin 3 PsyrB_25270 ENOG4107YZP Rhodanese domain protein PsyrB_25275 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) PsyrB_25280 ENOG41063SB peptidase PsyrB_25285 ENOG4105CN1 protease PsyrB_25290 ENOG4105PXI polysaccharide deacetylase PsyrB_25315 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) PsyrB_25320 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase PsyrB_25330 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) PsyrB_25340 ENOG4105CGF Aromatic amino acid aminotransferase PsyrB_25345 ENOG4105FCD Major Facilitator PsyrB_25355 ENOG4105CEN a g-specific adenine glycosylase PsyrB_25360 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) PsyrB_25385 ENOG4107SDU Methyl-accepting chemotaxis PsyrB_25400 ENOG4108JEH abc transporter atp-binding protein PsyrB_25405 ENOG4105E89 ABC transporter PsyrB_25410 ENOG4105GBT ABC transporter PsyrB_25435 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) PsyrB_25595 ENOG4105ED4 portal protein PsyrB_25635 ENOG4105D70 Integrase catalytic subunit PsyrB_25640 ENOG4105F5W AtP-binding protein PsyrB_25660 ENOG4105CAU Arsenical resistance protein, ArsH PsyrB_25675 ENOG41082YX Transcriptional regulator, arsr family PsyrB_25820 ENOG4105J5J Outer membrane porin PsyrB_25830 ENOG4105DWY Agmatine deiminase PsyrB_25845 ENOG4105C1B dTDP-glucose 4-6-dehydratase PsyrB_25850 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase PsyrB_25855 ENOG4105CQZ Histidine kinase PsyrB_25860 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family PsyrB_25870 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase PsyrB_25875 ENOG4107RK2 ADP-ribose diphosphatase NudE PsyrB_25880 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 PsyrB_25885 ENOG4109066 lysm domain bon superfamily protein PsyrB_25890 ENOG4105C5Q Transcriptional regulator PsyrB_25895 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) PsyrB_25900 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit PsyrB_25910 ENOG4105C9U ATP-dependent DNA helicase RecQ PsyrB_25955 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit PsyrB_25985 ENOG4105UYK outer membrane protein a PsyrB_26020 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) PsyrB_26075 ENOG4105CS6 Rhs element vgr protein PsyrB_26090 ENOG4105CNA YD repeat protein PsyrB_26110 ENOG4105CNA YD repeat protein PsyrB_26180 ENOG4105D64 Mechanosensitive ion channel PsyrB_26185 ENOG4107SDU Methyl-accepting chemotaxis PsyrB_26195 ENOG4107YBY Hydrolase PsyrB_26200 ENOG4105CPC Aldo Keto reductase PsyrB_26205 ENOG4105DRR Transcriptional regulator, GntR family PsyrB_26220 ENOG4105CEY Amp-dependent synthetase and ligase PsyrB_26270 ENOG4105C1G acyl-Coa dehydrogenase PsyrB_26275 ENOG4105ETT transcriptional Regulator, LysR family PsyrB_26280 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) PsyrB_26285 ENOG4105W8H transhydrogenase (subunit alpha PsyrB_26290 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) PsyrB_26295 ENOG4105CYC Transferase PsyrB_26335 ENOG4105NYX DNA-binding protein PsyrB_26340 ENOG4107QZF nitrite reductase NADPH large subunit PsyrB_26350 ENOG4105VEI Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity) PsyrB_26355 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) PsyrB_26360 ENOG4105CK6 Two component transcriptional regulator (Winged helix family PsyrB_26365 ENOG4105BZU Histidine kinase PsyrB_26370 ENOG4105C37 (CBS) domain PsyrB_26375 ENOG4105DR5 peptidase PsyrB_26380 ENOG4108VYJ response regulator receiver protein PsyrB_26385 ENOG4108UTW Plays a role in the regulation of phosphate uptake PsyrB_26390 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) PsyrB_26395 ENOG4105C8U phosphate abc transporter PsyrB_26400 ENOG4105C8U phosphate abc transporter PsyrB_26415 ENOG4105NAU thioesterase Superfamily protein PsyrB_26435 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit PsyrB_26440 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) PsyrB_26450 ENOG4107YNJ LysR family Transcriptional regulator PsyrB_26460 ENOG4108IJ0 Aspartate ammonia-lyase PsyrB_26470 ENOG4105HDK L-asparaginase PsyrB_26475 ENOG4105FFC UPF0187 protein PsyrB_26480 ENOG41066VF YeeE YedE family protein PsyrB_26505 ENOG4107QSA Oxaloacetate decarboxylase PsyrB_26510 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase PsyrB_26515 ENOG4105DUM transcriptional regulator, lysR family PsyrB_26530 ENOG4106KNT transcriptional regulator PsyrB_26535 ENOG4105C4R Atp-dependent dna helicase PsyrB_26550 ENOG4105CKD glutathione-regulated potassium-efflux system protein PsyrB_26560 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) PsyrB_26570 ENOG4105CKI cobalamin synthesis protein PsyrB_26595 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase PsyrB_26600 ENOG41060X7 Protein of unknown function (DUF3617) PsyrB_26605 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) PsyrB_26615 ENOG4105MZU cell filamentation protein PsyrB_26620 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase PsyrB_26655 ENOG4105EXC Acyl-transferase PsyrB_26660 ENOG4108ZXC Two component transcriptional regulator, luxr family PsyrB_26665 ENOG4105BZU Histidine kinase PsyrB_26680 ENOG4105C8Q Methyl-accepting chemotaxis PsyrB_26685 ENOG4108NVR Methyl-accepting chemotaxis PsyrB_26695 ENOG4105WEF catalase PsyrB_26705 ENOG4108Z9Z response to DNA damage stimulus PsyrB_26720 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) PsyrB_26730 ENOG4105C6Y Udp-glucose 6-dehydrogenase PsyrB_26740 ENOG4105CKK Glycosyl transferase, family 2 PsyrB_26745 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) PsyrB_26750 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) PsyrB_26755 ENOG4108ZK4 sdia-regulated domain-containing protein PsyrB_26775 ENOG4107TUY Histidine kinase PsyrB_26795 ENOG4105CS6 Rhs element vgr protein PsyrB_26810 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) PsyrB_26815 ENOG410804X Transcriptional regulator PsyrB_26820 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) PsyrB_26825 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) PsyrB_26830 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) PsyrB_26835 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) PsyrB_26840 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) PsyrB_26845 ENOG4107S15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) PsyrB_26850 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) PsyrB_26855 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) PsyrB_26860 ENOG4105EE4 it plays a direct role in the translocation of protons across the membrane (By similarity) PsyrB_26865 ENOG41064MJ ATP synthase, subunit I PsyrB_26870 ENOG4105FA0 parb-like partition protein PsyrB_26875 ENOG4107QJE Chromosome Partitioning Protein PsyrB_26880 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) PsyrB_26885 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) PsyrB_26890 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) PsyrB_26895 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins PsyrB_26900 ENOG4105NVJ RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)