locus-tag	class	description
PsyrB_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PsyrB_00010	COG0592	DNA-directed DNA polymerase activity
PsyrB_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PsyrB_00020	COG0187	DNA topoisomerase II activity
PsyrB_00035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PsyrB_00050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PsyrB_00055	COG0751	glycine-tRNA ligase activity
PsyrB_00060	COG0752	glycyl-tRNA synthetase alpha subunit
PsyrB_00065	COG2818	Glycosylase
PsyrB_00075	COG0243	molybdopterin cofactor binding
PsyrB_00080	COG0569	domain protein
PsyrB_00085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PsyrB_00090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PsyrB_00095	COG0242	peptide deformylase activity
PsyrB_00105	COG0758	DNA mediated transformation
PsyrB_00110	COG0009	L-threonylcarbamoyladenylate synthase
PsyrB_00120	COG0408	coproporphyrinogen oxidase activity
PsyrB_00125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PsyrB_00145	COG3119	arylsulfatase activity
PsyrB_00150	COG0583	DNA-binding transcription factor activity
PsyrB_00195	COG0159	tryptophan synthase activity
PsyrB_00200	COG0133	tryptophan synthase activity
PsyrB_00215	COG3360	Dodecin
PsyrB_00225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PsyrB_00230	COG1764	response to oxidative stress
PsyrB_00255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PsyrB_00265	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PsyrB_00280	COG0672	)-iron permease
PsyrB_00285	COG1280	lysine exporter protein (LysE YggA)
PsyrB_00295	COG0488	(ABC) transporter
PsyrB_00320	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PsyrB_00340	COG0181	hydroxymethylbilane synthase activity
PsyrB_00350	COG0745	RESPONSE REGULATOR receiver
PsyrB_00350	COG2972	Histidine kinase
PsyrB_00355	COG0165	Argininosuccinate lyase
PsyrB_00360	COG0700	Nucleoside recognition
PsyrB_00370	COG0612	Peptidase, M16
PsyrB_00375	COG1283	sodium-dependent phosphate transmembrane transporter activity
PsyrB_00385	COG0583	DNA-binding transcription factor activity
PsyrB_00390	COG0534	Mate efflux family protein
PsyrB_00405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PsyrB_00435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PsyrB_00440	COG4208	sulfate ABC transporter
PsyrB_00450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PsyrB_00470	COG3706	GGDEF domain
PsyrB_00470	COG0745	RESPONSE REGULATOR receiver
PsyrB_00475	COG0745	RESPONSE REGULATOR receiver
PsyrB_00480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PsyrB_00490	COG1012	belongs to the aldehyde dehydrogenase family
PsyrB_00495	COG1280	lysine exporter protein (LysE YggA)
PsyrB_00560	COG2814	Major facilitator Superfamily
PsyrB_00590	COG0596	Alpha beta hydrolase
PsyrB_00605	COG1280	lysine exporter protein (LysE YggA)
PsyrB_00630	COG2249	NAD(P)H dehydrogenase (quinone) activity
PsyrB_00650	COG3152	Membrane
PsyrB_00675	COG1522	sequence-specific DNA binding
PsyrB_00680	COG1104	cysteine desulfurase activity
PsyrB_00700	COG4771	TonB-dependent receptor
PsyrB_00705	COG4166	transmembrane transport
PsyrB_00710	COG4174	ABC transporter (Permease)
PsyrB_00715	COG4239	(ABC) transporter, permease
PsyrB_00720	COG4172	Belongs to the ABC transporter superfamily
PsyrB_00730	COG1522	sequence-specific DNA binding
PsyrB_00740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PsyrB_00780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PsyrB_00785	COG0601	transmembrane transport
PsyrB_00790	COG0747	negative chemotaxis
PsyrB_00795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PsyrB_00820	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PsyrB_00825	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PsyrB_00830	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PsyrB_00835	COG3287	FIST C domain
PsyrB_00835	COG2200	EAL domain
PsyrB_00835	COG2199	diguanylate cyclase activity
PsyrB_00840	COG0189	ligase activity
PsyrB_00840	COG4067	protein conserved in archaea
PsyrB_00845	COG0189	ligase activity
PsyrB_00850	COG1301	dicarboxylic acid transport
PsyrB_00865	COG3072	Adenylate cyclase
PsyrB_00870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PsyrB_00885	COG1965	Belongs to the frataxin family
PsyrB_00895	COG0019	diaminopimelate decarboxylase activity
PsyrB_00900	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PsyrB_00910	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PsyrB_00925	COG0432	Pfam Uncharacterised protein family UPF0047
PsyrB_00930	COG0004	ammonium transporteR
PsyrB_00935	COG0347	Belongs to the P(II) protein family
PsyrB_00950	COG2207	Transcriptional regulator
PsyrB_00955	COG4221	oxidoreductase activity
PsyrB_00990	COG2801	Transposase and inactivated derivatives
PsyrB_01050	COG0606	chelatase, subunit chli
PsyrB_01070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PsyrB_01085	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PsyrB_01095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PsyrB_01100	COG0210	DNA helicase
PsyrB_01160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PsyrB_01170	COG4372	Transposase
PsyrB_01185	COG3436	PFAM IS66 Orf2 family protein
PsyrB_01220	COG0606	chelatase, subunit chli
PsyrB_01225	COG2851	Citrate transporter
PsyrB_01240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PsyrB_01255	COG0848	biopolymer transport protein
PsyrB_01265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PsyrB_01280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PsyrB_01285	COG1758	RNA polymerase activity
PsyrB_01290	COG0194	GDP metabolic process
PsyrB_01295	COG1561	YicC-like family, N-terminal region
PsyrB_01300	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PsyrB_01310	COG0708	Exodeoxyribonuclease III
PsyrB_01315	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PsyrB_01325	COG2801	Transposase and inactivated derivatives
PsyrB_01335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PsyrB_01340	COG1121	(ABC) transporter
PsyrB_01345	COG0735	belongs to the Fur family
PsyrB_01350	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PsyrB_01375	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PsyrB_01380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PsyrB_01390	COG3706	GGDEF domain
PsyrB_01390	COG0745	RESPONSE REGULATOR receiver
PsyrB_01395	COG3023	N-Acetylmuramoyl-L-alanine amidase
PsyrB_01400	COG5002	protein histidine kinase activity
PsyrB_01405	COG2204	response regulator
PsyrB_01430	COG2205	protein histidine kinase activity
PsyrB_01435	COG0745	RESPONSE REGULATOR receiver
PsyrB_01440	COG2183	response to ionizing radiation
PsyrB_01470	COG1522	sequence-specific DNA binding
PsyrB_01500	COG0509	glycine decarboxylation via glycine cleavage system
PsyrB_01505	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PsyrB_01510	COG1178	ABC-type Fe3 transport system permease component
PsyrB_01530	COG0427	acetyl-CoA hydrolase
PsyrB_01545	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PsyrB_01555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PsyrB_01560	COG1522	sequence-specific DNA binding
PsyrB_01570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PsyrB_01580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PsyrB_01585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PsyrB_01595	COG1012	belongs to the aldehyde dehydrogenase family
PsyrB_01605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PsyrB_01610	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PsyrB_01615	COG0747	negative chemotaxis
PsyrB_01620	COG2003	Belongs to the UPF0758 family
PsyrB_01625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PsyrB_01630	COG0756	dUTP diphosphatase activity
PsyrB_01635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PsyrB_01640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PsyrB_01650	COG2801	Transposase and inactivated derivatives
PsyrB_01655	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PsyrB_01660	COG0735	belongs to the Fur family
PsyrB_01665	COG1121	(ABC) transporter
PsyrB_01670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PsyrB_01685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PsyrB_01690	COG2011	ABC-type metal ion transport system permease component
PsyrB_01705	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PsyrB_01715	COG0659	secondary active sulfate transmembrane transporter activity
PsyrB_01730	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PsyrB_01735	COG0586	Pfam SNARE associated Golgi protein
PsyrB_01745	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PsyrB_01750	COG0248	Ppx GppA phosphatase
PsyrB_01755	COG2801	Transposase and inactivated derivatives
PsyrB_01765	COG1126	abc transporter atp-binding protein
PsyrB_01775	COG0765	amino acid transport
PsyrB_01780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PsyrB_01785	COG2186	Transcriptional regulator
PsyrB_01805	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PsyrB_01820	COG2271	Major facilitator Superfamily
PsyrB_01880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PsyrB_01900	COG3079	Belongs to the UPF0149 family
PsyrB_01905	COG0006	proline dipeptidase activity
PsyrB_01910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PsyrB_01915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PsyrB_01925	COG2271	Major facilitator Superfamily
PsyrB_01950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PsyrB_01970	COG0662	Cupin 2, conserved barrel domain protein
PsyrB_01995	COG2369	cell adhesion
PsyrB_02005	COG2175	clavaminate synthase activity
PsyrB_02015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PsyrB_02055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PsyrB_02070	COG2011	ABC-type metal ion transport system permease component
PsyrB_02075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PsyrB_02125	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PsyrB_02130	COG1045	serine acetyltransferase
PsyrB_02150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PsyrB_02160	COG2188	Transcriptional regulator
PsyrB_02165	COG0402	S-adenosylhomocysteine deaminase activity
PsyrB_02170	COG3040	lipid binding
PsyrB_02180	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PsyrB_02200	COG0058	SHG alpha-glucan phosphorylase activity
PsyrB_02205	COG0596	Alpha beta hydrolase
PsyrB_02210	COG1490	D-aminoacyl-tRNA deacylase activity
PsyrB_02215	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PsyrB_02220	COG2943	transferase activity, transferring hexosyl groups
PsyrB_02230	COG2801	Transposase and inactivated derivatives
PsyrB_02235	COG0840	transmembrane signaling receptor activity
PsyrB_02240	COG0840	transmembrane signaling receptor activity
PsyrB_02255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PsyrB_02260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PsyrB_02265	COG0140	phosphoribosyl-ATP diphosphatase activity
PsyrB_02270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PsyrB_02275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PsyrB_02285	COG2226	methyltransferase
PsyrB_02305	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PsyrB_02310	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PsyrB_02320	COG0018	arginyl-trna synthetase
PsyrB_02325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PsyrB_02330	COG0254	rRNA binding
PsyrB_02340	COG0281	malic enzyme
PsyrB_02375	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PsyrB_02380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PsyrB_02390	COG0069	glutamate synthase activity
PsyrB_02390	COG0067	glutamate synthase
PsyrB_02390	COG0070	glutamate synthase
PsyrB_02395	COG0493	'glutamate synthase
PsyrB_02405	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PsyrB_02415	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PsyrB_02425	COG2610	gluconate transmembrane transporter activity
PsyrB_02435	COG2814	Major facilitator Superfamily
PsyrB_02440	COG0583	DNA-binding transcription factor activity
PsyrB_02445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PsyrB_02450	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_02460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PsyrB_02505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PsyrB_02515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PsyrB_02520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PsyrB_02535	COG1192	Involved in chromosome partitioning
PsyrB_02550	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
PsyrB_02555	COG3052	prosthetic group binding
PsyrB_02575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PsyrB_02595	COG1272	protein, Hemolysin III
PsyrB_02600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PsyrB_02615	COG3038	cytochrome b561
PsyrB_02620	COG2353	YceI-like domain
PsyrB_02625	COG0513	Belongs to the DEAD box helicase family
PsyrB_02630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PsyrB_02635	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PsyrB_02645	COG3622	Belongs to the hyi family
PsyrB_02650	COG2610	gluconate transmembrane transporter activity
PsyrB_02655	COG0235	Class ii aldolase
PsyrB_02660	COG3395	kinase activity
PsyrB_02665	COG2084	Dehydrogenase
PsyrB_02675	COG0436	Aminotransferase
PsyrB_02680	COG0129	dihydroxy-acid dehydratase activity
PsyrB_02690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PsyrB_02695	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PsyrB_02700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PsyrB_02700	COG2813	Specifically methylates the guanine in position
PsyrB_02705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PsyrB_02730	COG0791	NLP P60 protein
PsyrB_02740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PsyrB_02745	COG0540	Belongs to the ATCase OTCase family
PsyrB_02750	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PsyrB_02755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PsyrB_02760	COG1678	Uncharacterized ACR, COG1678
PsyrB_02770	COG0189	ligase activity
PsyrB_02795	COG2198	Histidine kinase
PsyrB_02795	COG0643	Histidine kinase
PsyrB_02805	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PsyrB_02810	COG1802	Transcriptional regulator
PsyrB_02815	COG1914	H( )-stimulated, divalent metal cation uptake system
PsyrB_02820	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PsyrB_02825	COG4336	lyase activity
PsyrB_02830	COG1984	allophanate hydrolase subunit 2
PsyrB_02835	COG4770	biotin carboxylase activity
PsyrB_02840	COG3264	Mechanosensitive ion channel
PsyrB_02840	COG1196	nuclear chromosome segregation
PsyrB_02845	COG3263	regulation of cellular component size
PsyrB_02860	COG1960	acyl-CoA dehydrogenase activity
PsyrB_02865	COG0506	proline dehydrogenase activity
PsyrB_02865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PsyrB_02865	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PsyrB_02870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PsyrB_02885	COG1451	nucleotide metabolic process
PsyrB_02895	COG2153	protein acetylation
PsyrB_02905	COG1289	transmembrane transporter activity
PsyrB_02910	COG2081	HI0933 family
PsyrB_02915	COG0513	Belongs to the DEAD box helicase family
PsyrB_02930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PsyrB_02935	COG0859	PFAM glycosyl transferase family 9
PsyrB_02945	COG0438	transferase activity, transferring glycosyl groups
PsyrB_02975	COG2192	nodulation
PsyrB_02980	COG0438	transferase activity, transferring glycosyl groups
PsyrB_03015	COG1132	(ABC) transporter
PsyrB_03020	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PsyrB_03020	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PsyrB_03030	COG0667	Aldo Keto reductase
PsyrB_03045	COG1519	Transferase
PsyrB_03050	COG1538	Outer membrane efflux protein
PsyrB_03055	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PsyrB_03070	COG0494	nUDIX hydrolase
PsyrB_03090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PsyrB_03095	COG3150	esterase
PsyrB_03130	COG0560	Phosphoserine phosphatase
PsyrB_03130	COG3830	Belongs to the UPF0237 family
PsyrB_03140	COG0688	phosphatidylethanolamine metabolic process
PsyrB_03160	COG1162	GTPase activity
PsyrB_03165	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PsyrB_03170	COG2860	membrane
PsyrB_03180	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PsyrB_03180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PsyrB_03185	COG0802	atpase or kinase
PsyrB_03190	COG0860	N-Acetylmuramoyl-L-alanine amidase
PsyrB_03195	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PsyrB_03200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PsyrB_03205	COG1923	regulation of RNA biosynthetic process
PsyrB_03210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PsyrB_03215	COG0330	HflC and HflK could
PsyrB_03220	COG0330	HflC and HflK could
PsyrB_03225	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PsyrB_03230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PsyrB_03250	COG0557	exoribonuclease II activity
PsyrB_03255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PsyrB_03265	COG0360	Binds together with S18 to 16S ribosomal RNA
PsyrB_03270	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PsyrB_03280	COG0359	binds to the 23S rRNA
PsyrB_03285	COG0305	Participates in initiation and elongation during chromosome replication
PsyrB_03295	COG1032	radical SAM domain protein
PsyrB_03305	COG2308	Evidence 4 Homologs of previously reported genes of
PsyrB_03305	COG2307	Protein conserved in bacteria
PsyrB_03320	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PsyrB_03325	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PsyrB_03330	COG0583	DNA-binding transcription factor activity
PsyrB_03340	COG0559	Belongs to the binding-protein-dependent transport system permease family
PsyrB_03355	COG0410	ABC transporter
PsyrB_03360	COG4221	oxidoreductase activity
PsyrB_03370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PsyrB_03375	COG0142	geranyltranstransferase activity
PsyrB_03380	COG1722	exodeoxyribonuclease VII activity
PsyrB_03395	COG0625	glutathione transferase activity
PsyrB_03420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PsyrB_03470	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PsyrB_03475	COG3228	Belongs to the MtfA family
PsyrB_03480	COG0586	Pfam SNARE associated Golgi protein
PsyrB_03485	COG4302	ethanolamine ammonia-lyase activity
PsyrB_03490	COG4303	Ethanolamine ammonia lyase large subunit
PsyrB_03495	COG1012	belongs to the aldehyde dehydrogenase family
PsyrB_03500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PsyrB_03515	COG0702	epimerase
PsyrB_03535	COG1346	cytolysis
PsyrB_03555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PsyrB_03575	COG0183	Belongs to the thiolase family
PsyrB_03595	COG2207	Transcriptional regulator
PsyrB_03610	COG2217	Heavy metal translocating P-type atpase
PsyrB_03615	COG2217	Heavy metal translocating P-type atpase
PsyrB_03630	COG2814	Major facilitator Superfamily
PsyrB_03640	COG0583	DNA-binding transcription factor activity
PsyrB_03650	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PsyrB_03665	COG1120	ATPase activity
PsyrB_03670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PsyrB_03675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PsyrB_03680	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
PsyrB_03685	COG0387	Pfam Sodium calcium exchanger
PsyrB_03720	COG1309	transcriptional regulator
PsyrB_03725	COG2233	PERMEase
PsyrB_03775	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PsyrB_03780	COG1074	ATP-dependent DNA helicase activity
PsyrB_03785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PsyrB_03825	COG3639	organic phosphonate transmembrane transporter activity
PsyrB_03830	COG3639	organic phosphonate transmembrane transporter activity
PsyrB_03835	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PsyrB_03840	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PsyrB_03845	COG0709	Synthesizes selenophosphate from selenide and ATP
PsyrB_03850	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PsyrB_03860	COG0142	geranyltranstransferase activity
PsyrB_03865	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PsyrB_03870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PsyrB_03875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PsyrB_03880	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PsyrB_03885	COG3045	CreA protein
PsyrB_03890	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PsyrB_03895	COG0268	Binds directly to 16S ribosomal RNA
PsyrB_03905	COG0196	riboflavin kinase activity
PsyrB_03910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PsyrB_03915	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PsyrB_03920	COG1047	Peptidyl-prolyl cis-trans
PsyrB_03925	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PsyrB_03965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PsyrB_04000	COG0542	response to heat
PsyrB_04050	COG0134	indole-3-glycerol-phosphate synthase activity
PsyrB_04060	COG1621	beta-fructofuranosidase activity
PsyrB_04080	COG1653	transport
PsyrB_04090	COG3386	PFAM SMP-30 Gluconolaconase
PsyrB_04100	COG3477	response to acidic pH
PsyrB_04105	COG0583	DNA-binding transcription factor activity
PsyrB_04115	COG2323	membrane
PsyrB_04125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PsyrB_04140	COG1172	Belongs to the binding-protein-dependent transport system permease family
PsyrB_04150	COG1879	ABC-type sugar transport system periplasmic component
PsyrB_04155	COG1609	Transcriptional regulator
PsyrB_04175	COG2201	protein-glutamate methylesterase activity
PsyrB_04180	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PsyrB_04190	COG0835	chemotaxis
PsyrB_04195	COG0840	transmembrane signaling receptor activity
PsyrB_04200	COG0643	Histidine kinase
PsyrB_04200	COG2198	Histidine kinase
PsyrB_04210	COG0745	RESPONSE REGULATOR receiver
PsyrB_04220	COG1252	NADH dehydrogenase
PsyrB_04240	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PsyrB_04245	COG0237	dephospho-CoA kinase activity
PsyrB_04250	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PsyrB_04300	COG1358	cellular component organization or biogenesis
PsyrB_04310	COG0560	Phosphoserine phosphatase
PsyrB_04360	COG3023	N-Acetylmuramoyl-L-alanine amidase
PsyrB_04370	COG0084	hydrolase, TatD family'
PsyrB_04375	COG1609	Transcriptional regulator
PsyrB_04385	COG1105	Belongs to the carbohydrate kinase PfkB family
PsyrB_04390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PsyrB_04390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PsyrB_04390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PsyrB_04405	COG0166	Belongs to the GPI family
PsyrB_04410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PsyrB_04415	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PsyrB_04435	COG2204	response regulator
PsyrB_04440	COG4191	Histidine kinase
PsyrB_04450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PsyrB_04455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PsyrB_04465	COG1489	DNA binding
PsyrB_04475	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PsyrB_04495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PsyrB_04515	COG0028	Belongs to the TPP enzyme family
PsyrB_04525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PsyrB_04530	COG1183	phosphatidylcholine synthase activity
PsyrB_04535	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PsyrB_04540	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PsyrB_04610	COG0288	reversible hydration of carbon dioxide
PsyrB_04620	COG1418	mRNA catabolic process
PsyrB_04630	COG2824	Alkylphosphonate utilization operon protein PhnA
PsyrB_04635	COG3011	Protein conserved in bacteria
PsyrB_04640	COG2814	Major facilitator Superfamily
PsyrB_04665	COG3706	GGDEF domain
PsyrB_04665	COG4251	negative regulation of phosphorylation
PsyrB_04665	COG2203	Gaf domain
PsyrB_04665	COG5001	Diguanylate cyclase
PsyrB_04675	COG3540	Alkaline phosphatase
PsyrB_04680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PsyrB_04700	COG0811	peptide transport
PsyrB_04710	COG1247	-acetyltransferase
PsyrB_04745	COG2204	response regulator
PsyrB_04755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PsyrB_04770	COG1595	DNA-templated transcription, initiation
PsyrB_04810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PsyrB_04820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PsyrB_04835	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_04840	COG0840	transmembrane signaling receptor activity
PsyrB_04845	COG0840	transmembrane signaling receptor activity
PsyrB_04855	COG1304	FMN binding
PsyrB_04860	COG0583	DNA-binding transcription factor activity
PsyrB_04915	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
PsyrB_04960	COG0463	Glycosyl transferase, family 2
PsyrB_04965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PsyrB_05000	COG0438	transferase activity, transferring glycosyl groups
PsyrB_05005	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PsyrB_05005	COG0662	Cupin 2, conserved barrel domain protein
PsyrB_05010	COG0012	GTP binding
PsyrB_05015	COG0193	aminoacyl-tRNA hydrolase activity
PsyrB_05020	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PsyrB_05025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PsyrB_05035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PsyrB_05040	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PsyrB_05050	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PsyrB_05055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PsyrB_05065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PsyrB_05070	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PsyrB_05090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PsyrB_05105	COG4221	oxidoreductase activity
PsyrB_05115	COG0415	Belongs to the DNA photolyase family
PsyrB_05120	COG0789	Transcriptional regulator
PsyrB_05135	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PsyrB_05140	COG1090	epimerase
PsyrB_05145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PsyrB_05155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PsyrB_05180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PsyrB_05190	COG0579	oxidoreductase
PsyrB_05225	COG2135	peptidase activity
PsyrB_05230	COG0501	Belongs to the peptidase M48B family
PsyrB_05235	COG2119	membrane
PsyrB_05240	COG2813	Specifically methylates the guanine in position
PsyrB_05245	COG1280	lysine exporter protein (LysE YggA)
PsyrB_05250	COG0318	PFAM AMP-dependent synthetase and ligase
PsyrB_05275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PsyrB_05280	COG0596	Alpha beta hydrolase
PsyrB_05285	COG0251	oxidation-reduction process
PsyrB_05290	COG1335	isochorismatase
PsyrB_05295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PsyrB_05300	COG1309	transcriptional regulator
PsyrB_05325	COG2885	chlorophyll binding
PsyrB_05330	COG0204	Acyl-transferase
PsyrB_05335	COG0280	phosphate acetyltransferase
PsyrB_05335	COG0857	belongs to the CobB CobQ family
PsyrB_05340	COG1047	Peptidyl-prolyl cis-trans
PsyrB_05345	COG0386	Belongs to the glutathione peroxidase family
PsyrB_05365	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
PsyrB_05370	COG0492	ferredoxin-NADP+ reductase activity
PsyrB_05385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PsyrB_05390	COG0302	gtp cyclohydrolase
PsyrB_05415	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_05440	COG1215	transferase activity, transferring glycosyl groups
PsyrB_05450	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PsyrB_05485	COG4772	TonB-dependent receptor
PsyrB_05490	COG3712	iron ion homeostasis
PsyrB_05505	COG0697	spore germination
PsyrB_05515	COG0583	DNA-binding transcription factor activity
PsyrB_05535	COG1566	PFAM secretion protein HlyD family protein
PsyrB_05540	COG0300	oxidoreductase activity
PsyrB_05560	COG0662	Cupin 2, conserved barrel domain protein
PsyrB_05560	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PsyrB_05575	COG1696	Membrane protein involved in D-alanine export
PsyrB_05590	COG3420	alginic acid biosynthetic process
PsyrB_05600	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PsyrB_05605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PsyrB_05610	COG1215	transferase activity, transferring glycosyl groups
PsyrB_05620	COG3022	response to hydroperoxide
PsyrB_05625	COG0726	polysaccharide deacetylase
PsyrB_05630	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PsyrB_05635	COG0315	cyclic pyranopterin monophosphate synthase activity
PsyrB_05640	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PsyrB_05650	COG0513	Belongs to the DEAD box helicase family
PsyrB_05660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PsyrB_05665	COG4597	amino acid ABC transporter
PsyrB_05670	COG0765	amino acid transport
PsyrB_05675	COG1126	abc transporter atp-binding protein
PsyrB_05680	COG2807	transmembrane transport
PsyrB_05700	COG2827	Endonuclease containing a URI domain
PsyrB_05715	COG3081	Nucleoid-associated protein
PsyrB_05725	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PsyrB_05730	COG0525	valine-tRNA ligase activity
PsyrB_05750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PsyrB_05755	COG0795	lipopolysaccharide-transporting ATPase activity
PsyrB_05760	COG0795	lipopolysaccharide-transporting ATPase activity
PsyrB_05765	COG1278	Cold shock
PsyrB_05770	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PsyrB_05775	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PsyrB_05775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PsyrB_05780	COG0509	glycine decarboxylation via glycine cleavage system
PsyrB_05790	COG0784	Response regulator, receiver
PsyrB_05795	COG2205	protein histidine kinase activity
PsyrB_05815	COG2832	Protein of unknown function (DUF454)
PsyrB_05835	COG1595	DNA-templated transcription, initiation
PsyrB_05855	COG0745	RESPONSE REGULATOR receiver
PsyrB_05860	COG2205	protein histidine kinase activity
PsyrB_05865	COG1653	transport
PsyrB_05900	COG1737	Transcriptional regulator
PsyrB_05915	COG0800	Aldolase
PsyrB_05920	COG3530	Putative quorum-sensing-regulated virulence factor
PsyrB_05930	COG5001	Diguanylate cyclase
PsyrB_05930	COG4251	negative regulation of phosphorylation
PsyrB_05930	COG2203	Gaf domain
PsyrB_05930	COG3706	GGDEF domain
PsyrB_05935	COG5002	protein histidine kinase activity
PsyrB_05965	COG3121	Chaperone
PsyrB_05970	COG3188	usher protein
PsyrB_05975	COG3121	Chaperone
PsyrB_06000	COG0835	chemotaxis
PsyrB_06000	COG0784	Response regulator, receiver
PsyrB_06005	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PsyrB_06015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PsyrB_06020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PsyrB_06025	COG1845	cytochrome c oxidase, subunit III
PsyrB_06035	COG0109	protoheme IX farnesyltransferase activity
PsyrB_06055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PsyrB_06075	COG0640	Transcriptional regulator
PsyrB_06080	COG3321	synthase
PsyrB_06080	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_06080	COG0604	alcohol dehydrogenase
PsyrB_06105	COG3706	GGDEF domain
PsyrB_06135	COG1802	Transcriptional regulator
PsyrB_06145	COG1335	isochorismatase
PsyrB_06155	COG1335	isochorismatase
PsyrB_06160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PsyrB_06200	COG2814	Major facilitator Superfamily
PsyrB_06230	COG3781	membrane
PsyrB_06265	COG0741	lytic transglycosylase activity
PsyrB_06265	COG1388	LysM domain
PsyrB_06350	COG4792	protein secretion
PsyrB_06360	COG4794	Type iii secretion
PsyrB_06435	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PsyrB_06440	COG0343	queuine tRNA-ribosyltransferase activity
PsyrB_06445	COG1862	Preprotein translocase
PsyrB_06460	COG3134	Outer membrane lipoprotein
PsyrB_06485	COG1104	cysteine desulfurase activity
PsyrB_06495	COG0316	Belongs to the HesB IscA family
PsyrB_06500	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PsyrB_06505	COG0443	Heat shock 70 kDa protein
PsyrB_06510	COG0633	Ferredoxin
PsyrB_06520	COG0105	UTP biosynthetic process
PsyrB_06525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PsyrB_06540	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PsyrB_06545	COG0124	histidyl-tRNA synthetase
PsyrB_06560	COG1160	GTP binding
PsyrB_06565	COG0436	Aminotransferase
PsyrB_06570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PsyrB_06580	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PsyrB_06585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PsyrB_06595	COG0739	heme binding
PsyrB_06600	COG1570	exodeoxyribonuclease VII activity
PsyrB_06615	COG0519	Catalyzes the synthesis of GMP from XMP
PsyrB_06615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PsyrB_06620	COG3604	Transcriptional regulator
PsyrB_06630	COG0477	Major facilitator Superfamily
PsyrB_06640	COG1942	4-Oxalocrotonate Tautomerase
PsyrB_06655	COG2132	Multicopper oxidase
PsyrB_06660	COG0590	tRNA wobble adenosine to inosine editing
PsyrB_06665	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PsyrB_06670	COG0047	phosphoribosylformylglycinamidine synthase activity
PsyrB_06670	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PsyrB_06690	COG0494	nUDIX hydrolase
PsyrB_06710	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PsyrB_06715	COG0477	Major facilitator Superfamily
PsyrB_06720	COG4536	flavin adenine dinucleotide binding
PsyrB_06730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PsyrB_06735	COG0228	four-way junction DNA binding
PsyrB_06740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PsyrB_06745	COG0336	Belongs to the RNA methyltransferase TrmD family
PsyrB_06750	COG0335	large ribosomal subunit rRNA binding
PsyrB_06755	COG4974	Belongs to the 'phage' integrase family
PsyrB_06765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PsyrB_06780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PsyrB_06780	COG2205	protein histidine kinase activity
PsyrB_06785	COG2203	Gaf domain
PsyrB_06785	COG4251	negative regulation of phosphorylation
PsyrB_06785	COG3706	GGDEF domain
PsyrB_06785	COG5001	Diguanylate cyclase
PsyrB_06790	COG2197	response regulator
PsyrB_06805	COG4681	YaeQ
PsyrB_06815	COG1902	pentaerythritol trinitrate reductase activity
PsyrB_06845	COG0457	Tetratricopeptide repeat
PsyrB_06845	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PsyrB_06860	COG2201	protein-glutamate methylesterase activity
PsyrB_06865	COG2203	Gaf domain
PsyrB_06865	COG4251	negative regulation of phosphorylation
PsyrB_06865	COG5001	Diguanylate cyclase
PsyrB_06865	COG3706	GGDEF domain
PsyrB_06870	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PsyrB_06875	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PsyrB_06890	COG1073	alpha beta
PsyrB_06900	COG3047	cAMP biosynthetic process
PsyrB_06900	COG2885	chlorophyll binding
PsyrB_06910	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PsyrB_06915	COG0563	adenylate kinase activity
PsyrB_06920	COG1214	PFAM Peptidase M22, glycoprotease
PsyrB_06945	COG0742	ribosomal rna small subunit methyltransferase
PsyrB_06960	COG2937	Belongs to the GPAT DAPAT family
PsyrB_06970	COG2226	methyltransferase
PsyrB_06975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PsyrB_06985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PsyrB_06990	COG2166	iron-sulfur cluster assembly
PsyrB_06995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PsyrB_07000	COG2171	N-acyltransferase activity
PsyrB_07005	COG1393	Belongs to the ArsC family
PsyrB_07020	COG0436	Aminotransferase
PsyrB_07025	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PsyrB_07030	COG0024	Methionine aminopeptidase
PsyrB_07040	COG0052	Belongs to the universal ribosomal protein uS2 family
PsyrB_07045	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PsyrB_07050	COG0528	UMP kinase activity
PsyrB_07055	COG0233	cytoplasmic translational termination
PsyrB_07060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PsyrB_07070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PsyrB_07080	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PsyrB_07090	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PsyrB_07095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PsyrB_07100	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PsyrB_07105	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PsyrB_07110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PsyrB_07115	COG0587	DNA-directed DNA polymerase activity
PsyrB_07120	COG0825	malonyl-CoA metabolic process
PsyrB_07125	COG0037	tRNA processing
PsyrB_07130	COG0504	CTP synthase activity
PsyrB_07135	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PsyrB_07140	COG0148	phosphopyruvate hydratase activity
PsyrB_07150	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PsyrB_07160	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PsyrB_07165	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PsyrB_07170	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PsyrB_07175	COG0585	pseudouridine synthase activity
PsyrB_07180	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PsyrB_07185	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PsyrB_07205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PsyrB_07210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PsyrB_07220	COG1546	Belongs to the CinA family
PsyrB_07225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PsyrB_07230	COG2137	regulation of response to DNA damage stimulus
PsyrB_07265	COG0583	DNA-binding transcription factor activity
PsyrB_07280	COG4807	Protein conserved in bacteria
PsyrB_07285	COG1187	pseudouridine synthase activity
PsyrB_07295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PsyrB_07305	COG3158	transport of potassium into the cell
PsyrB_07315	COG0392	lysyltransferase activity
PsyrB_07315	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PsyrB_07330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PsyrB_07340	COG0442	prolyl-tRNA aminoacylation
PsyrB_07355	COG2900	Belongs to the SlyX family
PsyrB_07365	COG0783	Belongs to the Dps family
PsyrB_07375	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PsyrB_07380	COG0217	transcriptional regulatory protein
PsyrB_07385	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PsyrB_07390	COG0632	four-way junction helicase activity
PsyrB_07395	COG2255	four-way junction helicase activity
PsyrB_07400	COG0824	Thioesterase
PsyrB_07420	COG0823	Involved in the tonB-independent uptake of proteins
PsyrB_07425	COG2885	chlorophyll binding
PsyrB_07430	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PsyrB_07435	COG0602	queuosine metabolic process
PsyrB_07440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PsyrB_07465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PsyrB_07475	COG0840	transmembrane signaling receptor activity
PsyrB_07490	COG0586	Pfam SNARE associated Golgi protein
PsyrB_07495	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PsyrB_07500	COG4783	chaperone-mediated protein folding
PsyrB_07505	COG0425	Belongs to the sulfur carrier protein TusA family
PsyrB_07515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PsyrB_07525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PsyrB_07530	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PsyrB_07535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PsyrB_07540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PsyrB_07550	COG1902	pentaerythritol trinitrate reductase activity
PsyrB_07555	COG0583	DNA-binding transcription factor activity
PsyrB_07570	COG0281	malic enzyme
PsyrB_07575	COG2194	sulfuric ester hydrolase activity
PsyrB_07585	COG3100	YcgL domain-containing protein
PsyrB_07590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PsyrB_07600	COG2983	Belongs to the UPF0260 family
PsyrB_07615	COG3667	copper resistance
PsyrB_07620	COG2132	Multicopper oxidase
PsyrB_07625	COG1403	HNH endonuclease
PsyrB_07635	COG1770	oligopeptidase
PsyrB_07645	COG0121	glutamine amidotransferase
PsyrB_07665	COG0542	response to heat
PsyrB_07680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PsyrB_07690	COG2205	protein histidine kinase activity
PsyrB_07695	COG0477	Major facilitator Superfamily
PsyrB_07705	COG0385	Bile acid
PsyrB_07710	COG2974	May be involved in recombination
PsyrB_07730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PsyrB_07785	COG0560	Phosphoserine phosphatase
PsyrB_07795	COG1176	ABC-type spermidine putrescine transport system, permease component I
PsyrB_07830	COG1362	aminopeptidase activity
PsyrB_07835	COG0564	pseudouridine synthase activity
PsyrB_07840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PsyrB_07845	COG2894	cell division
PsyrB_07850	COG0850	regulation of cytokinetic process
PsyrB_07855	COG1560	Kdo2-lipid A biosynthetic process
PsyrB_07875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PsyrB_07910	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PsyrB_07925	COG1960	acyl-CoA dehydrogenase activity
PsyrB_07930	COG0625	glutathione transferase activity
PsyrB_07935	COG1131	(ABC) transporter
PsyrB_07940	COG0842	Transport permease protein
PsyrB_07950	COG0811	peptide transport
PsyrB_07955	COG0848	biopolymer transport protein
PsyrB_07960	COG1663	tetraacyldisaccharide 4'-kinase activity
PsyrB_07965	COG2835	tetraacyldisaccharide 4'-kinase activity
PsyrB_07970	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PsyrB_07975	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PsyrB_07980	COG1530	ribonuclease E activity
PsyrB_08000	COG0616	signal peptide processing
PsyrB_08000	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PsyrB_08005	COG0424	maF-like protein
PsyrB_08010	COG1399	metal-binding, possibly nucleic acid-binding protein
PsyrB_08015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PsyrB_08020	COG0416	fatty acid biosynthetic process
PsyrB_08035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PsyrB_08040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PsyrB_08050	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PsyrB_08055	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PsyrB_08070	COG0084	hydrolase, TatD family'
PsyrB_08120	COG0135	phosphoribosylanthranilate isomerase activity
PsyrB_08125	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PsyrB_08130	COG0285	dihydrofolate synthase activity
PsyrB_08140	COG1286	toxin biosynthetic process
PsyrB_08180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PsyrB_08210	COG0446	pyridine nucleotide-disulphide oxidoreductase
PsyrB_08210	COG1902	pentaerythritol trinitrate reductase activity
PsyrB_08220	COG0477	Major facilitator Superfamily
PsyrB_08225	COG2223	nitrite transmembrane transporter activity
PsyrB_08240	COG3706	GGDEF domain
PsyrB_08245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PsyrB_08250	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PsyrB_08260	COG3139	Protein of unknown function (DUF1315)
PsyrB_08270	COG0308	aminopeptidase N
PsyrB_08300	COG3766	membrane
PsyrB_08310	COG0754	glutathionylspermidine amidase activity
PsyrB_08330	COG2197	response regulator
PsyrB_08335	COG3239	Fatty acid desaturase
PsyrB_08355	COG1609	Transcriptional regulator
PsyrB_08380	COG2706	6-phosphogluconolactonase activity
PsyrB_08395	COG0420	3'-5' exonuclease activity
PsyrB_08410	COG2304	oxidoreductase activity
PsyrB_08425	COG0714	Associated with various cellular activities
PsyrB_08445	COG1971	Probably functions as a manganese efflux pump
PsyrB_08465	COG1846	Transcriptional regulator
PsyrB_08470	COG1566	PFAM secretion protein HlyD family protein
PsyrB_08475	COG2814	Major facilitator Superfamily
PsyrB_08485	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PsyrB_08495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PsyrB_08500	COG0215	cysteine-tRNA ligase activity
PsyrB_08505	COG3284	Transcriptional regulator
PsyrB_08510	COG3842	ATPase activity
PsyrB_08515	COG3842	ATPase activity
PsyrB_08525	COG0395	ABC-type sugar transport system, permease component
PsyrB_08540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PsyrB_08560	COG0544	peptidyl-prolyl cis-trans isomerase activity
PsyrB_08565	COG0740	serine-type endopeptidase activity
PsyrB_08570	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PsyrB_08575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PsyrB_08580	COG0776	regulation of translation
PsyrB_08585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PsyrB_08600	COG4172	Belongs to the ABC transporter superfamily
PsyrB_08605	COG4239	(ABC) transporter, permease
PsyrB_08610	COG4174	ABC transporter (Permease)
PsyrB_08615	COG4166	transmembrane transport
PsyrB_08620	COG4166	transmembrane transport
PsyrB_08625	COG1388	LysM domain
PsyrB_08625	COG0741	lytic transglycosylase activity
PsyrB_08630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PsyrB_08640	COG0328	RNA-DNA hybrid ribonuclease activity
PsyrB_08645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PsyrB_08660	COG0431	NADPH-dependent FMN reductase
PsyrB_08670	COG1960	acyl-CoA dehydrogenase activity
PsyrB_08675	COG1024	Enoyl-CoA hydratase
PsyrB_08690	COG0306	phosphate transporter
PsyrB_08700	COG0656	L-ascorbic acid biosynthetic process
PsyrB_08705	COG0840	transmembrane signaling receptor activity
PsyrB_08710	COG1309	transcriptional regulator
PsyrB_08745	COG3046	protein related to deoxyribodipyrimidine photolyase
PsyrB_08770	COG0667	Aldo Keto reductase
PsyrB_08780	COG1214	PFAM Peptidase M22, glycoprotease
PsyrB_08780	COG0456	acetyltransferase
PsyrB_08805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PsyrB_08825	COG0840	transmembrane signaling receptor activity
PsyrB_08835	COG0583	DNA-binding transcription factor activity
PsyrB_08840	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PsyrB_08845	COG1522	sequence-specific DNA binding
PsyrB_08850	COG2354	Protein conserved in bacteria
PsyrB_08865	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
PsyrB_08870	COG4266	Belongs to the allantoicase family
PsyrB_08900	COG0402	S-adenosylhomocysteine deaminase activity
PsyrB_08930	COG3115	cell septum assembly
PsyrB_08935	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PsyrB_08945	COG0456	acetyltransferase
PsyrB_08955	COG0668	transmembrane transport
PsyrB_08970	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PsyrB_08975	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PsyrB_08980	COG0425	Belongs to the sulfur carrier protein TusA family
PsyrB_08985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PsyrB_08995	COG1132	(ABC) transporter
PsyrB_09000	COG3123	guanosine phosphorylase activity
PsyrB_09025	COG0284	orotidine-5'-phosphate decarboxylase activity
PsyrB_09030	COG2130	NADP-dependent
PsyrB_09035	COG1619	proteins homologs of microcin C7 resistance protein MccF
PsyrB_09040	COG3135	benzoate transporter
PsyrB_09050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PsyrB_09055	COG0625	glutathione transferase activity
PsyrB_09070	COG0302	gtp cyclohydrolase
PsyrB_09080	COG2840	Smr protein MutS2
PsyrB_09110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PsyrB_09120	COG0235	Class ii aldolase
PsyrB_09125	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PsyrB_09130	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
PsyrB_09135	COG2197	response regulator
PsyrB_09165	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PsyrB_09170	COG1368	sulfuric ester hydrolase activity
PsyrB_09185	COG2308	Evidence 4 Homologs of previously reported genes of
PsyrB_09195	COG1305	Transglutaminase-like
PsyrB_09210	COG0519	Catalyzes the synthesis of GMP from XMP
PsyrB_09210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PsyrB_09220	COG0598	Magnesium transport protein CorA
PsyrB_09305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PsyrB_09340	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_09345	COG1335	isochorismatase
PsyrB_09350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PsyrB_09360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PsyrB_09380	COG1477	protein flavinylation
PsyrB_09385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PsyrB_09390	COG0584	glycerophosphoryl diester phosphodiesterase
PsyrB_09400	COG4591	ABC-type transport system involved in lipoprotein release permease component
PsyrB_09405	COG1136	(ABC) transporter
PsyrB_09410	COG4591	ABC-type transport system involved in lipoprotein release permease component
PsyrB_09415	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PsyrB_09415	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PsyrB_09430	COG2853	Lipoprotein
PsyrB_09440	COG4566	intracellular signal transduction
PsyrB_09450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PsyrB_09470	COG5002	protein histidine kinase activity
PsyrB_09495	COG2814	Major facilitator Superfamily
PsyrB_09505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PsyrB_09520	COG0583	DNA-binding transcription factor activity
PsyrB_09570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PsyrB_09585	COG2205	protein histidine kinase activity
PsyrB_09635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PsyrB_09640	COG1121	(ABC) transporter
PsyrB_09740	COG1136	(ABC) transporter
PsyrB_09740	COG0577	efflux transmembrane transporter activity
PsyrB_09745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PsyrB_09750	COG2366	antibiotic biosynthetic process
PsyrB_09765	COG0556	nucleotide-excision repair
PsyrB_09770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PsyrB_09800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PsyrB_09820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PsyrB_09825	COG0066	3-isopropylmalate dehydratase activity
PsyrB_09830	COG0473	3-isopropylmalate dehydrogenase activity
PsyrB_09840	COG3734	2-keto-3-deoxy-galactonokinase
PsyrB_09845	COG0800	Aldolase
PsyrB_09850	COG4948	Mandelate Racemase Muconate Lactonizing
PsyrB_09855	COG2271	Major facilitator Superfamily
PsyrB_09860	COG1414	Transcriptional regulator
PsyrB_09865	COG1064	alcohol dehydrogenase
PsyrB_09870	COG2207	Transcriptional regulator
PsyrB_09905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PsyrB_09930	COG2009	succinate dehydrogenase
PsyrB_09935	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PsyrB_09940	COG1053	succinate dehydrogenase
PsyrB_09945	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PsyrB_09965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PsyrB_09975	COG0045	succinate-CoA ligase (ADP-forming) activity
PsyrB_10000	COG0326	Molecular chaperone. Has ATPase activity
PsyrB_10020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PsyrB_10025	COG5002	protein histidine kinase activity
PsyrB_10025	COG0784	Response regulator, receiver
PsyrB_10025	COG2205	protein histidine kinase activity
PsyrB_10030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PsyrB_10040	COG2062	phosphohistidine phosphatase, SixA
PsyrB_10065	COG0628	permease
PsyrB_10075	COG2205	protein histidine kinase activity
PsyrB_10080	COG0745	RESPONSE REGULATOR receiver
PsyrB_10110	COG3188	usher protein
PsyrB_10115	COG3121	Chaperone
PsyrB_10160	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PsyrB_10170	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PsyrB_10175	COG2205	protein histidine kinase activity
PsyrB_10180	COG0745	RESPONSE REGULATOR receiver
PsyrB_10190	COG0714	Associated with various cellular activities
PsyrB_10225	COG0084	hydrolase, TatD family'
PsyrB_10235	COG2259	Doxx family
PsyrB_10250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PsyrB_10255	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PsyrB_10260	COG4181	ATPase activity
PsyrB_10275	COG1376	ErfK ybiS ycfS ynhG family protein
PsyrB_10295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PsyrB_10300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PsyrB_10325	COG0560	Phosphoserine phosphatase
PsyrB_10345	COG4067	protein conserved in archaea
PsyrB_10345	COG0189	ligase activity
PsyrB_10350	COG1802	Transcriptional regulator
PsyrB_10360	COG0372	Belongs to the citrate synthase family
PsyrB_10375	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PsyrB_10390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PsyrB_10420	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PsyrB_10425	COG0243	molybdopterin cofactor binding
PsyrB_10430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PsyrB_10440	COG0515	serine threonine protein kinase
PsyrB_10440	COG2815	serine threonine protein kinase
PsyrB_10445	COG2223	nitrite transmembrane transporter activity
PsyrB_10460	COG3707	response regulator
PsyrB_10465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PsyrB_10465	COG1116	anion transmembrane transporter activity
PsyrB_10470	COG0167	dihydroorotate dehydrogenase activity
PsyrB_10475	COG3130	regulation of translation
PsyrB_10485	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PsyrB_10485	COG0116	Belongs to the methyltransferase superfamily
PsyrB_10495	COG3706	GGDEF domain
PsyrB_10505	COG3171	Protein conserved in bacteria
PsyrB_10515	COG2197	response regulator
PsyrB_10545	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PsyrB_10555	COG0583	DNA-binding transcription factor activity
PsyrB_10560	COG3485	protocatechuate 3,4-dioxygenase
PsyrB_10565	COG3485	protocatechuate 3,4-dioxygenase
PsyrB_10580	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PsyrB_10600	COG2271	Major facilitator Superfamily
PsyrB_10610	COG1309	transcriptional regulator
PsyrB_10615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PsyrB_10620	COG0564	pseudouridine synthase activity
PsyrB_10630	COG0746	molybdenum cofactor guanylyltransferase activity
PsyrB_10635	COG0521	Mo-molybdopterin cofactor biosynthetic process
PsyrB_10690	COG0024	Methionine aminopeptidase
PsyrB_10715	COG1879	ABC-type sugar transport system periplasmic component
PsyrB_10720	COG1129	ABC transporter
PsyrB_10725	COG1172	Belongs to the binding-protein-dependent transport system permease family
PsyrB_10730	COG1609	Transcriptional regulator
PsyrB_10735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PsyrB_10740	COG1869	D-ribose catabolic process
PsyrB_10760	COG1278	Cold shock
PsyrB_10770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PsyrB_10775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PsyrB_10785	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PsyrB_10790	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PsyrB_10795	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PsyrB_10800	COG0072	phenylalanine-tRNA ligase activity
PsyrB_10805	COG0776	regulation of translation
PsyrB_10820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PsyrB_10825	COG1012	belongs to the aldehyde dehydrogenase family
PsyrB_10830	COG2301	Belongs to the HpcH HpaI aldolase family
PsyrB_10835	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PsyrB_10855	COG1960	acyl-CoA dehydrogenase activity
PsyrB_10860	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
PsyrB_10860	COG0028	Belongs to the TPP enzyme family
PsyrB_10870	COG0477	Major facilitator Superfamily
PsyrB_10895	COG1802	Transcriptional regulator
PsyrB_10900	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_10905	COG3246	L-lysine catabolic process to acetate
PsyrB_10910	COG3386	PFAM SMP-30 Gluconolaconase
PsyrB_10925	COG0640	Transcriptional regulator
PsyrB_10930	COG1902	pentaerythritol trinitrate reductase activity
PsyrB_10955	COG0829	nickel cation binding
PsyrB_10960	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PsyrB_10965	COG0804	urea catabolic process
PsyrB_10970	COG0832	Belongs to the urease beta subunit family
PsyrB_10970	COG0831	urea catabolic process
PsyrB_10975	COG0830	nickel cation binding
PsyrB_10980	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PsyrB_11000	COG0559	Belongs to the binding-protein-dependent transport system permease family
PsyrB_11035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PsyrB_11045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PsyrB_11090	COG0840	transmembrane signaling receptor activity
PsyrB_11100	COG0446	pyridine nucleotide-disulphide oxidoreductase
PsyrB_11100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PsyrB_11115	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PsyrB_11195	COG0840	transmembrane signaling receptor activity
PsyrB_11205	COG0251	oxidation-reduction process
PsyrB_11210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PsyrB_11225	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PsyrB_11230	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PsyrB_11235	COG3639	organic phosphonate transmembrane transporter activity
PsyrB_11240	COG2188	Transcriptional regulator
PsyrB_11245	COG3624	Phosphonate C-P lyase system protein PhnG
PsyrB_11255	COG3626	phosphonate metabolism
PsyrB_11260	COG3627	carbon phosphorus lyase activity
PsyrB_11265	COG4107	phosphonate C-P lyase system protein PhnK
PsyrB_11270	COG4778	phosphonate C-P lyase system protein PhnL
PsyrB_11275	COG3454	Phosphonate metabolism
PsyrB_11280	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
PsyrB_11285	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PsyrB_11290	COG0154	amidase activity
PsyrB_11305	COG4608	Belongs to the ABC transporter superfamily
PsyrB_11310	COG0444	Belongs to the ABC transporter superfamily
PsyrB_11315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PsyrB_11320	COG0601	transmembrane transport
PsyrB_11335	COG1469	GTP cyclohydrolase I activity
PsyrB_11360	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PsyrB_11365	COG2218	PFAM glutamate synthase alpha subunit domain protein
PsyrB_11370	COG0069	glutamate synthase activity
PsyrB_11375	COG0004	ammonium transporteR
PsyrB_11385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PsyrB_11400	COG4251	negative regulation of phosphorylation
PsyrB_11400	COG5001	Diguanylate cyclase
PsyrB_11400	COG3706	GGDEF domain
PsyrB_11400	COG2203	Gaf domain
PsyrB_11410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PsyrB_11420	COG1999	signal sequence binding
PsyrB_11430	COG2801	Transposase and inactivated derivatives
PsyrB_11465	COG0235	Class ii aldolase
PsyrB_11470	COG2066	Belongs to the glutaminase family
PsyrB_11490	COG0667	Aldo Keto reductase
PsyrB_11500	COG3387	PFAM Glycoside hydrolase 15-related
PsyrB_11520	COG0277	FAD linked oxidase domain protein
PsyrB_11525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PsyrB_11525	COG0546	phosphoglycolate phosphatase activity
PsyrB_11535	COG2271	Major facilitator Superfamily
PsyrB_11545	COG2271	Major facilitator Superfamily
PsyrB_11575	COG0702	epimerase
PsyrB_11580	COG1733	regulation of RNA biosynthetic process
PsyrB_11585	COG0768	penicillin binding
PsyrB_11590	COG0028	Belongs to the TPP enzyme family
PsyrB_11620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PsyrB_11650	COG1177	transmembrane transport
PsyrB_11655	COG1176	ABC-type spermidine putrescine transport system, permease component I
PsyrB_11660	COG3842	ATPase activity
PsyrB_11665	COG1414	Transcriptional regulator
PsyrB_11675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PsyrB_11675	COG0116	Belongs to the methyltransferase superfamily
PsyrB_11700	COG1253	flavin adenine dinucleotide binding
PsyrB_11730	COG3501	Rhs element vgr protein
PsyrB_11825	COG1247	-acetyltransferase
PsyrB_11850	COG0840	transmembrane signaling receptor activity
PsyrB_11855	COG0583	DNA-binding transcription factor activity
PsyrB_11860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PsyrB_11875	COG0417	DNA replication proofreading
PsyrB_11880	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PsyrB_11885	COG0384	phenazine biosynthesis protein PhzF
PsyrB_11900	COG1121	(ABC) transporter
PsyrB_11910	COG0803	Belongs to the bacterial solute-binding protein 9 family
PsyrB_11920	COG3386	PFAM SMP-30 Gluconolaconase
PsyrB_11925	COG1879	ABC-type sugar transport system periplasmic component
PsyrB_11930	COG1129	ABC transporter
PsyrB_11935	COG1172	Belongs to the binding-protein-dependent transport system permease family
PsyrB_11940	COG5002	protein histidine kinase activity
PsyrB_11945	COG0745	RESPONSE REGULATOR receiver
PsyrB_11950	COG3713	MltA-interacting MipA family protein
PsyrB_11955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PsyrB_11990	COG0784	Response regulator, receiver
PsyrB_11995	COG4251	negative regulation of phosphorylation
PsyrB_12005	COG0579	oxidoreductase
PsyrB_12010	COG2080	2 iron, 2 sulfur cluster binding
PsyrB_12015	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PsyrB_12020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PsyrB_12025	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PsyrB_12035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PsyrB_12040	COG1012	belongs to the aldehyde dehydrogenase family
PsyrB_12045	COG0583	DNA-binding transcription factor activity
PsyrB_12055	COG0583	DNA-binding transcription factor activity
PsyrB_12060	COG3842	ATPase activity
PsyrB_12070	COG1176	ABC-type spermidine putrescine transport system, permease component I
PsyrB_12075	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PsyrB_12080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PsyrB_12105	COG1012	belongs to the aldehyde dehydrogenase family
PsyrB_12110	COG2267	carboxylic ester hydrolase activity
PsyrB_12125	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_12140	COG3483	tryptophan 2,3-dioxygenase activity
PsyrB_12150	COG0076	glutamate decarboxylase activity
PsyrB_12155	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_12165	COG1686	Belongs to the peptidase S11 family
PsyrB_12185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PsyrB_12190	COG3132	Protein of unknown function, DUF480
PsyrB_12200	COG2814	Major facilitator Superfamily
PsyrB_12205	COG0583	DNA-binding transcription factor activity
PsyrB_12215	COG1253	flavin adenine dinucleotide binding
PsyrB_12230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PsyrB_12305	COG1064	alcohol dehydrogenase
PsyrB_12325	COG1070	Carbohydrate kinase
PsyrB_12330	COG0246	Mannitol dehydrogenase
PsyrB_12345	COG1175	transmembrane transport
PsyrB_12350	COG1653	transport
PsyrB_12370	COG0745	RESPONSE REGULATOR receiver
PsyrB_12380	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PsyrB_12405	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PsyrB_12410	COG1024	Enoyl-CoA hydratase
PsyrB_12415	COG2816	NAD+ diphosphatase activity
PsyrB_12425	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_12445	COG0616	signal peptide processing
PsyrB_12455	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PsyrB_12465	COG1879	ABC-type sugar transport system periplasmic component
PsyrB_12475	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PsyrB_12480	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PsyrB_12480	COG0316	Belongs to the HesB IscA family
PsyrB_12490	COG1024	Enoyl-CoA hydratase
PsyrB_12495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PsyrB_12500	COG1960	acyl-CoA dehydrogenase activity
PsyrB_12515	COG0789	Transcriptional regulator
PsyrB_12525	COG1960	acyl-CoA dehydrogenase activity
PsyrB_12530	COG2885	chlorophyll binding
PsyrB_12535	COG0708	Exodeoxyribonuclease III
PsyrB_12545	COG0729	surface antigen
PsyrB_12555	COG0583	DNA-binding transcription factor activity
PsyrB_12565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PsyrB_12575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PsyrB_12580	COG1538	Outer membrane efflux protein
PsyrB_12590	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_12610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PsyrB_12620	COG2814	Major facilitator Superfamily
PsyrB_12625	COG2706	6-phosphogluconolactonase activity
PsyrB_12630	COG0488	(ABC) transporter
PsyrB_12660	COG0625	glutathione transferase activity
PsyrB_12690	COG0765	amino acid transport
PsyrB_12695	COG0765	amino acid transport
PsyrB_12700	COG1126	abc transporter atp-binding protein
PsyrB_12720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PsyrB_12725	COG0210	DNA helicase
PsyrB_12740	COG1116	anion transmembrane transporter activity
PsyrB_12745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PsyrB_12750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PsyrB_12760	COG0667	Aldo Keto reductase
PsyrB_12765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PsyrB_12780	COG0587	DNA-directed DNA polymerase activity
PsyrB_12790	COG0598	Magnesium transport protein CorA
PsyrB_12810	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PsyrB_12825	COG0583	DNA-binding transcription factor activity
PsyrB_12830	COG0583	DNA-binding transcription factor activity
PsyrB_12835	COG0247	lactate metabolic process
PsyrB_12835	COG0277	FAD linked oxidase domain protein
PsyrB_12845	COG0745	RESPONSE REGULATOR receiver
PsyrB_12845	COG3706	GGDEF domain
PsyrB_12860	COG2072	flavoprotein involved in K transport
PsyrB_12865	COG0601	transmembrane transport
PsyrB_12875	COG0444	Belongs to the ABC transporter superfamily
PsyrB_12885	COG0747	negative chemotaxis
PsyrB_12900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PsyrB_12955	COG0574	Belongs to the PEP-utilizing enzyme family
PsyrB_12955	COG3848	Pyruvate phosphate dikinase
PsyrB_13010	COG2376	Dihydroxyacetone kinase
PsyrB_13015	COG1063	alcohol dehydrogenase
PsyrB_13020	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_13025	COG1879	ABC-type sugar transport system periplasmic component
PsyrB_13030	COG1172	Belongs to the binding-protein-dependent transport system permease family
PsyrB_13035	COG1129	ABC transporter
PsyrB_13040	COG0698	ribose 5-phosphate isomerase
PsyrB_13045	COG2390	Transcriptional regulator
PsyrB_13080	COG1595	DNA-templated transcription, initiation
PsyrB_13085	COG3712	iron ion homeostasis
PsyrB_13095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PsyrB_13100	COG4264	IucA IucC family
PsyrB_13105	COG0019	diaminopimelate decarboxylase activity
PsyrB_13110	COG2814	Major facilitator Superfamily
PsyrB_13115	COG4264	IucA IucC family
PsyrB_13125	COG4264	IucA IucC family
PsyrB_13130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PsyrB_13135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PsyrB_13140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PsyrB_13145	COG1120	ATPase activity
PsyrB_13155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PsyrB_13165	COG5001	Diguanylate cyclase
PsyrB_13165	COG3300	MHYT domain
PsyrB_13175	COG1408	metallophosphoesterase
PsyrB_13195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PsyrB_13215	COG1538	Outer membrane efflux protein
PsyrB_13240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PsyrB_13270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PsyrB_13275	COG0577	efflux transmembrane transporter activity
PsyrB_13275	COG1136	(ABC) transporter
PsyrB_13310	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
PsyrB_13320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PsyrB_13340	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PsyrB_13390	COG0384	phenazine biosynthesis protein PhzF
PsyrB_13400	COG0583	DNA-binding transcription factor activity
PsyrB_13405	COG2851	Citrate transporter
PsyrB_13425	COG0444	Belongs to the ABC transporter superfamily
PsyrB_13430	COG4608	Belongs to the ABC transporter superfamily
PsyrB_13465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PsyrB_13470	COG0463	Glycosyl transferase, family 2
PsyrB_13475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PsyrB_13475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PsyrB_13480	COG0726	polysaccharide deacetylase
PsyrB_13485	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PsyrB_13490	COG2076	Multidrug Resistance protein
PsyrB_13495	COG2076	Multidrug Resistance protein
PsyrB_13520	COG0784	Response regulator, receiver
PsyrB_13520	COG4191	Histidine kinase
PsyrB_13545	COG1396	sequence-specific DNA binding
PsyrB_13545	COG1917	Cupin 2, conserved barrel domain protein
PsyrB_13575	COG5001	Diguanylate cyclase
PsyrB_13585	COG0583	DNA-binding transcription factor activity
PsyrB_13600	COG4948	Mandelate Racemase Muconate Lactonizing
PsyrB_13605	COG3008	intermembrane lipid transfer
PsyrB_13605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PsyrB_13615	COG2433	Pfam Transposase IS66
PsyrB_13625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PsyrB_13630	COG1126	abc transporter atp-binding protein
PsyrB_13635	COG0765	amino acid transport
PsyrB_13645	COG4221	oxidoreductase activity
PsyrB_13650	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PsyrB_13660	COG1984	allophanate hydrolase subunit 2
PsyrB_13665	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PsyrB_13675	COG0511	ligase activity, forming carbon-carbon bonds
PsyrB_13715	COG1984	allophanate hydrolase subunit 2
PsyrB_13725	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PsyrB_13740	COG0183	Belongs to the thiolase family
PsyrB_13745	COG1022	Amp-dependent synthetase and ligase
PsyrB_13745	COG3320	Male sterility
PsyrB_13750	COG1012	belongs to the aldehyde dehydrogenase family
PsyrB_13755	COG1024	Enoyl-CoA hydratase
PsyrB_13770	COG2814	Major facilitator Superfamily
PsyrB_13815	COG4977	sequence-specific DNA binding
PsyrB_13830	COG1280	lysine exporter protein (LysE YggA)
PsyrB_13845	COG3486	L-lysine 6-monooxygenase (NADPH) activity
PsyrB_13855	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PsyrB_13855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PsyrB_13870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PsyrB_13880	COG0604	alcohol dehydrogenase
PsyrB_13885	COG1309	transcriptional regulator
PsyrB_13905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PsyrB_13955	COG3179	chitinase
PsyrB_14275	COG0038	chloride channel
PsyrB_14300	COG0148	phosphopyruvate hydratase activity
PsyrB_14305	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PsyrB_14310	COG1294	oxidase, subunit
PsyrB_14315	COG1271	oxidase subunit
PsyrB_14330	COG0583	DNA-binding transcription factor activity
PsyrB_14355	COG3278	Belongs to the heme-copper respiratory oxidase family
PsyrB_14360	COG2010	Cytochrome c
PsyrB_14375	COG1484	DNA-dependent DNA replication
PsyrB_14505	COG0270	DNA (cytosine-5-)-methyltransferase activity
PsyrB_14550	COG3397	chitin binding
PsyrB_14565	COG1335	isochorismatase
PsyrB_14600	COG1538	Outer membrane efflux protein
PsyrB_14615	COG2205	protein histidine kinase activity
PsyrB_14620	COG0745	RESPONSE REGULATOR receiver
PsyrB_14645	COG1172	Belongs to the binding-protein-dependent transport system permease family
PsyrB_14650	COG1172	Belongs to the binding-protein-dependent transport system permease family
PsyrB_14655	COG1129	ABC transporter
PsyrB_14685	COG1609	Transcriptional regulator
PsyrB_14685	COG2207	Transcriptional regulator
PsyrB_14690	COG2115	Belongs to the xylose isomerase family
PsyrB_14695	COG4213	ABC transporter substrate-binding protein
PsyrB_14700	COG1129	ABC transporter
PsyrB_14705	COG4214	carbohydrate transport
PsyrB_14715	COG1231	oxidoreductase activity
PsyrB_14725	COG1126	abc transporter atp-binding protein
PsyrB_14760	COG0322	excinuclease ABC activity
PsyrB_14765	COG2197	response regulator
PsyrB_14785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PsyrB_14790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PsyrB_14800	COG4174	ABC transporter (Permease)
PsyrB_14805	COG4239	(ABC) transporter, permease
PsyrB_14810	COG4172	Belongs to the ABC transporter superfamily
PsyrB_14820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PsyrB_14835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PsyrB_14875	COG3246	L-lysine catabolic process to acetate
PsyrB_14880	COG1250	3-hydroxyacyl-CoA dehydrogenase
PsyrB_14895	COG1397	ADP-ribosylglycohydrolase
PsyrB_14905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PsyrB_14925	COG2814	Major facilitator Superfamily
PsyrB_14930	COG1309	transcriptional regulator
PsyrB_14935	COG1132	(ABC) transporter
PsyrB_14940	COG0583	DNA-binding transcription factor activity
PsyrB_14960	COG1309	transcriptional regulator
PsyrB_14965	COG1902	pentaerythritol trinitrate reductase activity
PsyrB_14980	COG0702	epimerase
PsyrB_14990	COG0583	DNA-binding transcription factor activity
PsyrB_14995	COG5001	Diguanylate cyclase
PsyrB_14995	COG4251	negative regulation of phosphorylation
PsyrB_14995	COG3706	GGDEF domain
PsyrB_14995	COG2203	Gaf domain
PsyrB_15000	COG2205	protein histidine kinase activity
PsyrB_15000	COG5002	protein histidine kinase activity
PsyrB_15000	COG0784	Response regulator, receiver
PsyrB_15005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PsyrB_15010	COG1126	abc transporter atp-binding protein
PsyrB_15020	COG0765	amino acid transport
PsyrB_15030	COG1942	4-Oxalocrotonate Tautomerase
PsyrB_15055	COG0038	chloride channel
PsyrB_15080	COG0148	phosphopyruvate hydratase activity
PsyrB_15085	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PsyrB_15090	COG1294	oxidase, subunit
PsyrB_15095	COG1271	oxidase subunit
PsyrB_15110	COG0583	DNA-binding transcription factor activity
PsyrB_15135	COG3278	Belongs to the heme-copper respiratory oxidase family
PsyrB_15140	COG2010	Cytochrome c
PsyrB_15155	COG1484	DNA-dependent DNA replication
PsyrB_15175	COG0778	Nitroreductase
PsyrB_15185	COG2267	carboxylic ester hydrolase activity
PsyrB_15200	COG3384	dioxygenase
PsyrB_15215	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PsyrB_15220	COG3791	Glutathione-dependent formaldehyde-activating
PsyrB_15230	COG0601	transmembrane transport
PsyrB_15250	COG0765	amino acid transport
PsyrB_15255	COG0765	amino acid transport
PsyrB_15260	COG1126	abc transporter atp-binding protein
PsyrB_15265	COG0840	transmembrane signaling receptor activity
PsyrB_15305	COG3634	alkyl hydroperoxide reductase activity
PsyrB_15310	COG0450	alkyl hydroperoxide reductase
PsyrB_15325	COG0784	Response regulator, receiver
PsyrB_15325	COG4191	Histidine kinase
PsyrB_15365	COG3387	PFAM Glycoside hydrolase 15-related
PsyrB_15370	COG0561	phosphatase activity
PsyrB_15375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PsyrB_15380	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PsyrB_15395	COG0297	glycogen (starch) synthase activity
PsyrB_15400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PsyrB_15405	COG1640	4-alpha-glucanotransferase
PsyrB_15455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PsyrB_15460	COG0583	DNA-binding transcription factor activity
PsyrB_15465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PsyrB_15480	COG1968	undecaprenyl-diphosphatase activity
PsyrB_15495	COG2204	response regulator
PsyrB_15550	COG1522	sequence-specific DNA binding
PsyrB_15565	COG2866	Carboxypeptidase
PsyrB_15585	COG0217	transcriptional regulatory protein
PsyrB_15595	COG1024	Enoyl-CoA hydratase
PsyrB_15600	COG0183	Belongs to the thiolase family
PsyrB_15665	COG2995	paraquat-inducible protein a
PsyrB_15670	COG2995	paraquat-inducible protein a
PsyrB_15675	COG3008	intermembrane lipid transfer
PsyrB_15690	COG0583	DNA-binding transcription factor activity
PsyrB_15695	COG1741	Belongs to the pirin family
PsyrB_15700	COG0667	Aldo Keto reductase
PsyrB_15705	COG0583	DNA-binding transcription factor activity
PsyrB_15730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PsyrB_15735	COG1349	DNA-binding transcription factor activity
PsyrB_15740	COG0154	amidase activity
PsyrB_15760	COG0583	DNA-binding transcription factor activity
PsyrB_15775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PsyrB_15790	COG2070	2-Nitropropane dioxygenase
PsyrB_15800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PsyrB_15805	COG0473	3-isopropylmalate dehydrogenase activity
PsyrB_15805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PsyrB_15810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PsyrB_15820	COG3039	Transposase
PsyrB_15825	COG3039	Transposase
PsyrB_15835	COG3210	domain, Protein
PsyrB_15850	COG3210	domain, Protein
PsyrB_15855	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
PsyrB_15870	COG3210	domain, Protein
PsyrB_15890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PsyrB_15900	COG1538	Outer membrane efflux protein
PsyrB_15905	COG0745	RESPONSE REGULATOR receiver
PsyrB_15910	COG2205	protein histidine kinase activity
PsyrB_15915	COG0659	secondary active sulfate transmembrane transporter activity
PsyrB_15920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PsyrB_15935	COG0745	RESPONSE REGULATOR receiver
PsyrB_15945	COG0406	alpha-ribazole phosphatase activity
PsyrB_15955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PsyrB_15960	COG1120	ATPase activity
PsyrB_15965	COG0826	peptidase U32
PsyrB_15975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PsyrB_15975	COG2146	nitrite reductase [NAD(P)H] activity
PsyrB_15980	COG2146	nitrite reductase [NAD(P)H] activity
PsyrB_15980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PsyrB_15985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PsyrB_15995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PsyrB_16000	COG0581	inorganic phosphate transmembrane transporter activity
PsyrB_16005	COG0573	inorganic phosphate transmembrane transporter activity
PsyrB_16010	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PsyrB_16035	COG0583	DNA-binding transcription factor activity
PsyrB_16040	COG3180	Ammonia monooxygenase
PsyrB_16055	COG1929	Belongs to the glycerate kinase type-1 family
PsyrB_16060	COG3835	regulator
PsyrB_16090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PsyrB_16110	COG2116	formate transmembrane transporter activity
PsyrB_16115	COG0745	RESPONSE REGULATOR receiver
PsyrB_16125	COG2267	carboxylic ester hydrolase activity
PsyrB_16135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PsyrB_16140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PsyrB_16170	COG2814	Major facilitator Superfamily
PsyrB_16185	COG1450	Type ii and iii secretion system protein
PsyrB_16205	COG3156	type II secretion system protein K
PsyrB_16220	COG2165	general secretion pathway protein
PsyrB_16225	COG2165	general secretion pathway protein
PsyrB_16230	COG1459	type II secretion system
PsyrB_16235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PsyrB_16250	COG1309	transcriptional regulator
PsyrB_16260	COG0583	DNA-binding transcription factor activity
PsyrB_16265	COG1012	belongs to the aldehyde dehydrogenase family
PsyrB_16295	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
PsyrB_16310	COG0583	DNA-binding transcription factor activity
PsyrB_16345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PsyrB_16350	COG0435	Glutathione S-transferase
PsyrB_16355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PsyrB_16355	COG1648	precorrin-2 dehydrogenase activity
PsyrB_16360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PsyrB_16365	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PsyrB_16370	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PsyrB_16375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PsyrB_16380	COG1674	ftsk spoiiie
PsyrB_16385	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PsyrB_16390	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PsyrB_16395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PsyrB_16400	COG0542	response to heat
PsyrB_16405	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PsyrB_16410	COG1278	Cold shock
PsyrB_16435	COG0482	sulfurtransferase activity
PsyrB_16440	COG2915	High frequency lysogenization protein hflD homolog
PsyrB_16450	COG2850	peptidyl-arginine hydroxylation
PsyrB_16455	COG2153	protein acetylation
PsyrB_16470	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PsyrB_16475	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PsyrB_16480	COG0649	NAD binding
PsyrB_16480	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PsyrB_16495	COG1034	ATP synthesis coupled electron transport
PsyrB_16500	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PsyrB_16505	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PsyrB_16515	COG0713	ATP synthesis coupled electron transport
PsyrB_16540	COG2205	protein histidine kinase activity
PsyrB_16545	COG0745	RESPONSE REGULATOR receiver
PsyrB_16560	COG0720	synthase
PsyrB_16575	COG0720	synthase
PsyrB_16610	COG5006	permease, DMT superfamily
PsyrB_16625	COG1104	cysteine desulfurase activity
PsyrB_16645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PsyrB_16650	COG3206	protein involved in exopolysaccharide biosynthesis
PsyrB_16650	COG0489	protein tyrosine kinase activity
PsyrB_16675	COG0438	transferase activity, transferring glycosyl groups
PsyrB_16680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PsyrB_16685	COG1596	polysaccharide export
PsyrB_16690	COG0431	NADPH-dependent FMN reductase
PsyrB_16705	COG0583	DNA-binding transcription factor activity
PsyrB_16725	COG2031	fatty acid transporter
PsyrB_16730	COG2329	Antibiotic biosynthesis monooxygenase
PsyrB_16735	COG0504	CTP synthase activity
PsyrB_16740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PsyrB_16745	COG0584	glycerophosphoryl diester phosphodiesterase
PsyrB_16755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PsyrB_16765	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PsyrB_16770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PsyrB_16775	COG3829	transcription factor binding
PsyrB_16800	COG2111	Na H antiporter
PsyrB_16800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PsyrB_16805	COG1006	Multisubunit Na H antiporter MnhC subunit
PsyrB_16810	COG0651	ATP synthesis coupled electron transport
PsyrB_16815	COG0651	ATP synthesis coupled electron transport
PsyrB_16825	COG2212	antiporter activity
PsyrB_16830	COG1320	monovalent cation:proton antiporter activity
PsyrB_16855	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PsyrB_16860	COG4211	Belongs to the binding-protein-dependent transport system permease family
PsyrB_16865	COG1129	ABC transporter
PsyrB_16880	COG0673	inositol 2-dehydrogenase activity
PsyrB_16885	COG1082	Xylose isomerase domain protein TIM barrel
PsyrB_16890	COG0673	inositol 2-dehydrogenase activity
PsyrB_16895	COG3962	Belongs to the TPP enzyme family
PsyrB_16910	COG3718	enzyme involved in inositol metabolism
PsyrB_16920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PsyrB_16930	COG0392	lysyltransferase activity
PsyrB_16935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PsyrB_16940	COG3568	Endonuclease Exonuclease Phosphatase
PsyrB_16950	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PsyrB_16965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PsyrB_16995	COG0183	Belongs to the thiolase family
PsyrB_17000	COG1250	3-hydroxyacyl-CoA dehydrogenase
PsyrB_17000	COG1024	Enoyl-CoA hydratase
PsyrB_17010	COG0589	response to stress
PsyrB_17020	COG0741	lytic transglycosylase activity
PsyrB_17025	COG0633	Ferredoxin
PsyrB_17025	COG3217	Mosc domain protein beta barrel domain protein
PsyrB_17040	COG2197	response regulator
PsyrB_17045	COG1597	lipid kinase activity
PsyrB_17050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PsyrB_17055	COG0662	Cupin 2, conserved barrel domain protein
PsyrB_17055	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PsyrB_17085	COG0438	transferase activity, transferring glycosyl groups
PsyrB_17100	COG0728	peptidoglycan biosynthetic process
PsyrB_17105	COG0583	DNA-binding transcription factor activity
PsyrB_17145	COG2807	transmembrane transport
PsyrB_17160	COG0179	Fumarylacetoacetate (FAA) hydrolase
PsyrB_17165	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PsyrB_17175	COG2203	Gaf domain
PsyrB_17175	COG4251	negative regulation of phosphorylation
PsyrB_17175	COG3706	GGDEF domain
PsyrB_17175	COG5001	Diguanylate cyclase
PsyrB_17190	COG0277	FAD linked oxidase domain protein
PsyrB_17195	COG0277	FAD linked oxidase domain protein
PsyrB_17200	COG0247	lactate metabolic process
PsyrB_17205	COG3193	protein, possibly involved in utilization of glycolate and propanediol
PsyrB_17215	COG1609	Transcriptional regulator
PsyrB_17220	COG3265	gluconokinase activity
PsyrB_17230	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PsyrB_17255	COG0456	acetyltransferase
PsyrB_17260	COG4774	siderophore transport
PsyrB_17310	COG4191	Histidine kinase
PsyrB_17310	COG0784	Response regulator, receiver
PsyrB_17320	COG0583	DNA-binding transcription factor activity
PsyrB_17335	COG2223	nitrite transmembrane transporter activity
PsyrB_17345	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PsyrB_17350	COG0659	secondary active sulfate transmembrane transporter activity
PsyrB_17360	COG2169	Transcriptional regulator
PsyrB_17360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PsyrB_17365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PsyrB_17375	COG2822	iron ion transport
PsyrB_17380	COG2837	iron assimilation
PsyrB_17390	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PsyrB_17395	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
PsyrB_17425	COG1289	transmembrane transporter activity
PsyrB_17435	COG1566	PFAM secretion protein HlyD family protein
PsyrB_17445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PsyrB_17450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PsyrB_17475	COG1138	Cytochrome C-type biogenesis protein
PsyrB_17480	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PsyrB_17500	COG4133	protoheme IX ABC transporter activity
PsyrB_17510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PsyrB_17515	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PsyrB_17540	COG1247	-acetyltransferase
PsyrB_17550	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PsyrB_17565	COG0840	transmembrane signaling receptor activity
PsyrB_17610	COG3278	Belongs to the heme-copper respiratory oxidase family
PsyrB_17625	COG2010	Cytochrome c
PsyrB_17640	COG0348	domain, Protein
PsyrB_17650	COG2217	Heavy metal translocating P-type atpase
PsyrB_17675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PsyrB_17680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PsyrB_17690	COG0835	chemotaxis
PsyrB_17700	COG1192	Involved in chromosome partitioning
PsyrB_17710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PsyrB_17715	COG2201	protein-glutamate methylesterase activity
PsyrB_17720	COG2198	Histidine kinase
PsyrB_17720	COG0643	Histidine kinase
PsyrB_17725	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PsyrB_17740	COG0455	bacterial-type flagellum organization
PsyrB_17750	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PsyrB_17755	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PsyrB_17765	COG1987	bacterial-type flagellum assembly
PsyrB_17810	COG0745	RESPONSE REGULATOR receiver
PsyrB_17845	COG1677	Flagellar hook-basal body complex protein FliE
PsyrB_17850	COG2204	response regulator
PsyrB_17855	COG3852	Histidine kinase
PsyrB_17860	COG2204	response regulator
PsyrB_17890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PsyrB_17895	COG1216	Glycosyl transferase, family 2
PsyrB_17895	COG0438	transferase activity, transferring glycosyl groups
PsyrB_17900	COG1216	Glycosyl transferase, family 2
PsyrB_17900	COG0438	transferase activity, transferring glycosyl groups
PsyrB_17920	COG1706	bacterial-type flagellum-dependent cell motility
PsyrB_17925	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PsyrB_17930	COG4786	Flagellar basal body rod
PsyrB_17935	COG4787	bacterial-type flagellum-dependent cell motility
PsyrB_17950	COG1749	Flagellar hook protein flgE
PsyrB_17955	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PsyrB_17960	COG1558	bacterial-type flagellum-dependent cell motility
PsyrB_17965	COG1815	bacterial-type flagellum-dependent cell motility
PsyrB_17975	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
PsyrB_17980	COG0583	DNA-binding transcription factor activity
PsyrB_17985	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PsyrB_17990	COG0784	Response regulator, receiver
PsyrB_17990	COG0835	chemotaxis
PsyrB_18010	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PsyrB_18015	COG0477	Major facilitator Superfamily
PsyrB_18045	COG4991	sh3 domain protein
PsyrB_18050	COG1611	Belongs to the LOG family
PsyrB_18065	COG2271	Major facilitator Superfamily
PsyrB_18085	COG4251	negative regulation of phosphorylation
PsyrB_18120	COG0745	RESPONSE REGULATOR receiver
PsyrB_18125	COG0642	Histidine kinase
PsyrB_18130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PsyrB_18135	COG1012	belongs to the aldehyde dehydrogenase family
PsyrB_18140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PsyrB_18145	COG5383	Protein conserved in bacteria
PsyrB_18160	COG0583	DNA-binding transcription factor activity
PsyrB_18165	COG1760	l-serine dehydratase
PsyrB_18170	COG1473	amidohydrolase
PsyrB_18185	COG0583	DNA-binding transcription factor activity
PsyrB_18190	COG1063	alcohol dehydrogenase
PsyrB_18205	COG1953	Uracil, thiamine, allantoin
PsyrB_18210	COG0784	Response regulator, receiver
PsyrB_18210	COG4191	Histidine kinase
PsyrB_18245	COG0300	oxidoreductase activity
PsyrB_18250	COG0604	alcohol dehydrogenase
PsyrB_18255	COG0300	oxidoreductase activity
PsyrB_18260	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_18265	COG2207	Transcriptional regulator
PsyrB_18270	COG3268	Saccharopine dehydrogenase
PsyrB_18280	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_18285	COG2207	Transcriptional regulator
PsyrB_18300	COG1196	nuclear chromosome segregation
PsyrB_18300	COG3264	Mechanosensitive ion channel
PsyrB_18325	COG2239	Acts as a magnesium transporter
PsyrB_18350	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PsyrB_18355	COG0527	aspartate kinase activity
PsyrB_18360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PsyrB_18365	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PsyrB_18370	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PsyrB_18375	COG2988	succinylglutamate desuccinylase activity
PsyrB_18385	COG3724	N-succinylarginine dihydrolase activity
PsyrB_18390	COG1012	belongs to the aldehyde dehydrogenase family
PsyrB_18405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PsyrB_18430	COG4215	(ABC) transporter
PsyrB_18440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PsyrB_18450	COG3283	Transcriptional regulator of aromatic amino acids metabolism
PsyrB_18460	COG2154	pterin-4-alpha-carbinolamine dehydratase
PsyrB_18495	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PsyrB_18505	COG0009	L-threonylcarbamoyladenylate synthase
PsyrB_18510	COG0613	PHP domain protein
PsyrB_18515	COG2917	probably involved in intracellular septation
PsyrB_18520	COG2350	Protein conserved in bacteria
PsyrB_18525	COG0745	RESPONSE REGULATOR receiver
PsyrB_18535	COG0642	Histidine kinase
PsyrB_18540	COG0778	Nitroreductase
PsyrB_18545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PsyrB_18565	COG1116	anion transmembrane transporter activity
PsyrB_18570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PsyrB_18575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PsyrB_18580	COG0583	DNA-binding transcription factor activity
PsyrB_18595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PsyrB_18600	COG1960	acyl-CoA dehydrogenase activity
PsyrB_18605	COG0583	DNA-binding transcription factor activity
PsyrB_18610	COG1741	Belongs to the pirin family
PsyrB_18640	COG1956	GAF domain-containing protein
PsyrB_18650	COG3850	Histidine kinase
PsyrB_18650	COG3437	response regulator, receiver
PsyrB_18650	COG2205	protein histidine kinase activity
PsyrB_18650	COG4999	Histidine kinase
PsyrB_18660	COG0386	Belongs to the glutathione peroxidase family
PsyrB_18665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PsyrB_18670	COG0436	Aminotransferase
PsyrB_18675	COG0501	Belongs to the peptidase M48B family
PsyrB_18680	COG0500	methyltransferase
PsyrB_18685	COG3384	dioxygenase
PsyrB_18700	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PsyrB_18710	COG0583	DNA-binding transcription factor activity
PsyrB_18720	COG1846	Transcriptional regulator
PsyrB_18725	COG1764	response to oxidative stress
PsyrB_18730	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PsyrB_18755	COG0814	amino acid
PsyrB_18760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PsyrB_18770	COG1555	photosystem II stabilization
PsyrB_18780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PsyrB_18790	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PsyrB_18800	COG0776	regulation of translation
PsyrB_18810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PsyrB_18815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PsyrB_18825	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PsyrB_18840	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PsyrB_18845	COG0402	S-adenosylhomocysteine deaminase activity
PsyrB_18850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PsyrB_18855	COG0546	phosphoglycolate phosphatase activity
PsyrB_18860	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_18865	COG3706	GGDEF domain
PsyrB_18875	COG5002	protein histidine kinase activity
PsyrB_18875	COG5001	Diguanylate cyclase
PsyrB_18895	COG0271	Belongs to the BolA IbaG family
PsyrB_18905	COG0114	fumarate hydratase activity
PsyrB_18915	COG0697	spore germination
PsyrB_18965	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PsyrB_18975	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PsyrB_18985	COG1492	cobalamin metabolic process
PsyrB_18995	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PsyrB_19000	COG0778	Nitroreductase
PsyrB_19005	COG1797	cobyrinic acid a,c-diamide synthase activity
PsyrB_19020	COG0791	NLP P60 protein
PsyrB_19025	COG1388	LysM domain
PsyrB_19025	COG0791	NLP P60 protein
PsyrB_19030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PsyrB_19040	COG0628	permease
PsyrB_19050	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PsyrB_19055	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PsyrB_19075	COG3956	TIGRFAM MazG family protein
PsyrB_19080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PsyrB_19085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PsyrB_19110	COG3118	belongs to the thioredoxin family
PsyrB_19115	COG1393	Belongs to the ArsC family
PsyrB_19125	COG2818	Glycosylase
PsyrB_19130	COG0037	tRNA processing
PsyrB_19135	COG3091	SprT-like family
PsyrB_19140	COG1301	dicarboxylic acid transport
PsyrB_19150	COG0745	RESPONSE REGULATOR receiver
PsyrB_19185	COG2205	protein histidine kinase activity
PsyrB_19190	COG0745	RESPONSE REGULATOR receiver
PsyrB_19195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PsyrB_19195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PsyrB_19200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PsyrB_19210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PsyrB_19210	COG1372	Participates in initiation and elongation during chromosome replication
PsyrB_19220	COG1401	restriction endodeoxyribonuclease activity
PsyrB_19260	COG0840	transmembrane signaling receptor activity
PsyrB_19275	COG1846	Transcriptional regulator
PsyrB_19280	COG0514	ATP-dependent DNA helicase (RecQ)
PsyrB_19290	COG2832	Protein of unknown function (DUF454)
PsyrB_19295	COG2326	polyphosphate kinase activity
PsyrB_19300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PsyrB_19300	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PsyrB_19305	COG4181	ATPase activity
PsyrB_19325	COG0367	asparagine synthase
PsyrB_19335	COG1363	Peptidase, m42
PsyrB_19340	COG3089	Belongs to the UPF0270 family
PsyrB_19345	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PsyrB_19350	COG1742	UPF0060 membrane protein
PsyrB_19370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PsyrB_19375	COG3162	membrane
PsyrB_19395	COG2853	Lipoprotein
PsyrB_19410	COG3706	GGDEF domain
PsyrB_19445	COG2133	pyrroloquinoline quinone binding
PsyrB_19460	COG2205	protein histidine kinase activity
PsyrB_19465	COG0596	Alpha beta hydrolase
PsyrB_19470	COG0590	tRNA wobble adenosine to inosine editing
PsyrB_19490	COG0242	peptide deformylase activity
PsyrB_19495	COG1295	ribonuclease BN
PsyrB_19500	COG3237	CsbD-like
PsyrB_19515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PsyrB_19520	COG2996	Protein conserved in bacteria
PsyrB_19550	COG0513	Belongs to the DEAD box helicase family
PsyrB_19560	COG0745	RESPONSE REGULATOR receiver
PsyrB_19580	COG2249	NAD(P)H dehydrogenase (quinone) activity
PsyrB_19610	COG0668	transmembrane transport
PsyrB_19630	COG3039	Transposase
PsyrB_19690	COG2433	Pfam Transposase IS66
PsyrB_19725	COG4584	PFAM Integrase catalytic
PsyrB_19730	COG1484	DNA-dependent DNA replication
PsyrB_19750	COG0431	NADPH-dependent FMN reductase
PsyrB_19760	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PsyrB_19765	COG0640	Transcriptional regulator
PsyrB_19810	COG0583	DNA-binding transcription factor activity
PsyrB_19815	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_19860	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_19895	COG1132	(ABC) transporter
PsyrB_19900	COG1132	(ABC) transporter
PsyrB_19920	COG1643	Atp-dependent helicase
PsyrB_19935	COG0318	PFAM AMP-dependent synthetase and ligase
PsyrB_19940	COG0318	PFAM AMP-dependent synthetase and ligase
PsyrB_19945	COG2030	dehydratase
PsyrB_19950	COG3866	Pectate lyase
PsyrB_19965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PsyrB_20010	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PsyrB_20025	COG0259	pyridoxamine-phosphate oxidase activity
PsyrB_20040	COG1199	ATP-dependent helicase activity
PsyrB_20050	COG3248	Nucleoside-binding outer membrane protein
PsyrB_20075	COG3012	SEC-C Motif Domain Protein
PsyrB_20110	COG0653	protein targeting
PsyrB_20115	COG2366	antibiotic biosynthetic process
PsyrB_20120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PsyrB_20120	COG1793	dna ligase
PsyrB_20125	COG1793	dna ligase
PsyrB_20135	COG4215	(ABC) transporter
PsyrB_20140	COG4160	amino acid transport
PsyrB_20155	COG1201	RNA secondary structure unwinding
PsyrB_20170	COG0717	Belongs to the dCTP deaminase family
PsyrB_20175	COG1278	Cold shock
PsyrB_20180	COG0489	protein tyrosine kinase activity
PsyrB_20185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PsyrB_20185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PsyrB_20190	COG2878	Part of a membrane complex involved in electron transport
PsyrB_20195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PsyrB_20205	COG2197	response regulator
PsyrB_20215	COG0137	argininosuccinate synthase activity
PsyrB_20225	COG0418	dihydroorotase activity
PsyrB_20230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PsyrB_20240	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PsyrB_20245	COG0243	molybdopterin cofactor binding
PsyrB_20255	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PsyrB_20265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PsyrB_20275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PsyrB_20295	COG0765	amino acid transport
PsyrB_20300	COG0765	amino acid transport
PsyrB_20305	COG1126	abc transporter atp-binding protein
PsyrB_20325	COG0596	Alpha beta hydrolase
PsyrB_20330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PsyrB_20335	COG0583	DNA-binding transcription factor activity
PsyrB_20345	COG1181	Belongs to the D-alanine--D-alanine ligase family
PsyrB_20350	COG0254	rRNA binding
PsyrB_20380	COG1695	Transcriptional regulator
PsyrB_20385	COG2375	cellular response to nickel ion
PsyrB_20395	COG4628	conserved protein (DUF2132)
PsyrB_20415	COG0523	cobalamin synthesis protein
PsyrB_20430	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_20450	COG2188	Transcriptional regulator
PsyrB_20475	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PsyrB_20485	COG2226	methyltransferase
PsyrB_20490	COG0500	methyltransferase
PsyrB_20495	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PsyrB_20500	COG1381	Involved in DNA repair and RecF pathway recombination
PsyrB_20505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PsyrB_20510	COG0571	ribonuclease III activity
PsyrB_20520	COG0681	Belongs to the peptidase S26 family
PsyrB_20525	COG0481	GTPase activity
PsyrB_20530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PsyrB_20555	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PsyrB_20560	COG0354	folic acid binding
PsyrB_20570	COG0642	Histidine kinase
PsyrB_20600	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PsyrB_20625	COG1116	anion transmembrane transporter activity
PsyrB_20625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PsyrB_20635	COG3665	Urea carboxylase-associated protein
PsyrB_20645	COG0439	Biotin carboxylase
PsyrB_20650	COG0511	ligase activity, forming carbon-carbon bonds
PsyrB_20670	COG2267	carboxylic ester hydrolase activity
PsyrB_20700	COG1454	alcohol dehydrogenase
PsyrB_20735	COG4191	Histidine kinase
PsyrB_20745	COG0784	Response regulator, receiver
PsyrB_20745	COG4191	Histidine kinase
PsyrB_20750	COG0443	Heat shock 70 kDa protein
PsyrB_20760	COG0477	Major facilitator Superfamily
PsyrB_20805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PsyrB_20810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PsyrB_20815	COG1538	Outer membrane efflux protein
PsyrB_20820	COG0477	Major facilitator Superfamily
PsyrB_20825	COG0183	Belongs to the thiolase family
PsyrB_20830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PsyrB_20835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PsyrB_20840	COG1414	Transcriptional regulator
PsyrB_20850	COG0306	phosphate transporter
PsyrB_20860	COG0788	formyltetrahydrofolate deformylase activity
PsyrB_20870	COG2925	Exonuclease
PsyrB_20930	COG0714	Associated with various cellular activities
PsyrB_20950	COG0469	pyruvate kinase activity
PsyrB_20955	COG0543	2 iron, 2 sulfur cluster binding
PsyrB_21030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PsyrB_21070	COG2814	Major facilitator Superfamily
PsyrB_21075	COG1902	pentaerythritol trinitrate reductase activity
PsyrB_21090	COG0702	epimerase
PsyrB_21095	COG0583	DNA-binding transcription factor activity
PsyrB_21145	COG3642	lipopolysaccharide core region biosynthetic process
PsyrB_21155	COG0642	Histidine kinase
PsyrB_21170	COG0459	protein refolding
PsyrB_21175	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PsyrB_21185	COG3030	protein affecting phage T7 exclusion by the F plasmid
PsyrB_21190	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_21200	COG3695	enzyme binding
PsyrB_21215	COG3501	Rhs element vgr protein
PsyrB_21245	COG0668	transmembrane transport
PsyrB_21250	COG1666	GTP binding
PsyrB_21260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PsyrB_21260	COG4191	Histidine kinase
PsyrB_21265	COG2096	Adenosyltransferase
PsyrB_21270	COG0494	nUDIX hydrolase
PsyrB_21280	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PsyrB_21285	COG0653	protein targeting
PsyrB_21295	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PsyrB_21300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PsyrB_21315	COG1181	Belongs to the D-alanine--D-alanine ligase family
PsyrB_21320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PsyrB_21325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PsyrB_21330	COG0772	Belongs to the SEDS family
PsyrB_21335	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PsyrB_21340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PsyrB_21345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PsyrB_21350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PsyrB_21365	COG0275	rRNA processing
PsyrB_21370	COG2001	Belongs to the MraZ family
PsyrB_21385	COG3107	peptidoglycan biosynthetic process
PsyrB_21390	COG0792	nuclease activity
PsyrB_21395	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PsyrB_21400	COG2823	Periplasmic or secreted lipoprotein
PsyrB_21405	COG2969	positive regulation of protein catabolic process
PsyrB_21410	COG0625	glutathione transferase activity
PsyrB_21415	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PsyrB_21420	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PsyrB_21430	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PsyrB_21435	COG0180	Tryptophanyl-tRNA synthetase
PsyrB_21455	COG0175	sulfate reduction
PsyrB_21465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PsyrB_21470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PsyrB_21475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PsyrB_21480	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PsyrB_21485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PsyrB_21505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PsyrB_21510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PsyrB_21515	COG1127	ABC transporter
PsyrB_21525	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PsyrB_21535	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PsyrB_21540	COG1137	ATPase activity
PsyrB_21545	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PsyrB_21550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PsyrB_21560	COG1660	Displays ATPase and GTPase activities
PsyrB_21585	COG0312	modulator of DNA gyrase
PsyrB_21590	COG3028	Belongs to the UPF0307 family
PsyrB_21595	COG0312	modulator of DNA gyrase
PsyrB_21600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PsyrB_21610	COG1530	ribonuclease E activity
PsyrB_21615	COG0424	maF-like protein
PsyrB_21625	COG1792	Involved in formation and maintenance of cell shape
PsyrB_21630	COG1077	Cell shape determining protein MreB Mrl
PsyrB_21635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PsyrB_21640	COG0154	amidase activity
PsyrB_21645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PsyrB_21650	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PsyrB_21660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PsyrB_21675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PsyrB_21690	COG2823	Periplasmic or secreted lipoprotein
PsyrB_21695	COG1185	polyribonucleotide nucleotidyltransferase activity
PsyrB_21700	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PsyrB_21710	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PsyrB_21715	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PsyrB_21720	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PsyrB_21725	COG0195	Participates in both transcription termination and antitermination
PsyrB_21730	COG0779	Required for maturation of 30S ribosomal subunits
PsyrB_21745	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PsyrB_21750	COG0149	triose-phosphate isomerase activity
PsyrB_21755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PsyrB_21760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PsyrB_21765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PsyrB_21770	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PsyrB_21780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PsyrB_21785	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PsyrB_21790	COG0505	Belongs to the CarA family
PsyrB_21800	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PsyrB_21805	COG0484	heat shock protein binding
PsyrB_21815	COG0443	Heat shock 70 kDa protein
PsyrB_21820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PsyrB_21825	COG0497	DNA recombination
PsyrB_21835	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PsyrB_21840	COG2914	Belongs to the UPF0125 (RnfH) family
PsyrB_21850	COG0733	neurotransmitter:sodium symporter activity
PsyrB_21855	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PsyrB_21875	COG3706	GGDEF domain
PsyrB_21885	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PsyrB_21895	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PsyrB_21905	COG4608	Belongs to the ABC transporter superfamily
PsyrB_21910	COG0444	Belongs to the ABC transporter superfamily
PsyrB_21920	COG0601	transmembrane transport
PsyrB_21930	COG2197	response regulator
PsyrB_21955	COG5001	Diguanylate cyclase
PsyrB_21960	COG0730	response to heat
PsyrB_21980	COG2721	sulfolactate sulfo-lyase activity
PsyrB_21985	COG2271	Major facilitator Superfamily
PsyrB_21990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PsyrB_21995	COG2186	Transcriptional regulator
PsyrB_22000	COG4178	(ABC) transporter
PsyrB_22005	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PsyrB_22025	COG0747	negative chemotaxis
PsyrB_22030	COG0747	negative chemotaxis
PsyrB_22035	COG0747	negative chemotaxis
PsyrB_22045	COG0747	negative chemotaxis
PsyrB_22050	COG0601	transmembrane transport
PsyrB_22055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PsyrB_22060	COG0444	Belongs to the ABC transporter superfamily
PsyrB_22065	COG4608	Belongs to the ABC transporter superfamily
PsyrB_22070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PsyrB_22090	COG0019	diaminopimelate decarboxylase activity
PsyrB_22115	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PsyrB_22120	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PsyrB_22125	COG0545	Peptidyl-prolyl cis-trans isomerase
PsyrB_22135	COG2862	Uncharacterized protein family, UPF0114
PsyrB_22145	COG1067	ATP-dependent peptidase activity
PsyrB_22165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PsyrB_22170	COG0488	(ABC) transporter
PsyrB_22200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PsyrB_22205	COG0523	cobalamin synthesis protein
PsyrB_22210	COG2879	small protein
PsyrB_22215	COG1966	Carbon starvation protein
PsyrB_22230	COG1970	mechanosensitive ion channel activity
PsyrB_22240	COG2197	response regulator
PsyrB_22245	COG2813	Specifically methylates the guanine in position
PsyrB_22255	COG1294	oxidase, subunit
PsyrB_22260	COG1271	oxidase subunit
PsyrB_22265	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PsyrB_22270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PsyrB_22275	COG2080	2 iron, 2 sulfur cluster binding
PsyrB_22280	COG2252	PERMEase
PsyrB_22285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PsyrB_22295	COG2321	neutral zinc metallopeptidase
PsyrB_22310	COG1946	Acyl-CoA thioesterase
PsyrB_22320	COG0123	including yeast histone deacetylase and acetoin utilization protein
PsyrB_22330	COG0513	Belongs to the DEAD box helicase family
PsyrB_22335	COG0697	spore germination
PsyrB_22340	COG1522	sequence-specific DNA binding
PsyrB_22345	COG1199	ATP-dependent helicase activity
PsyrB_22345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PsyrB_22355	COG3416	Protein conserved in bacteria
PsyrB_22380	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PsyrB_22405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PsyrB_22405	COG3321	synthase
PsyrB_22405	COG1028	Short-chain dehydrogenase reductase Sdr
PsyrB_22405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PsyrB_22405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PsyrB_22410	COG4221	oxidoreductase activity
PsyrB_22410	COG3321	synthase
PsyrB_22410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PsyrB_22410	COG0300	oxidoreductase activity
PsyrB_22415	COG0300	oxidoreductase activity
PsyrB_22415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PsyrB_22415	COG3321	synthase
PsyrB_22415	COG4221	oxidoreductase activity
PsyrB_22420	COG0367	asparagine synthase
PsyrB_22435	COG0583	DNA-binding transcription factor activity
PsyrB_22440	COG1643	Atp-dependent helicase
PsyrB_22450	COG2814	Major facilitator Superfamily
PsyrB_22460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PsyrB_22465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PsyrB_22470	COG0484	heat shock protein binding
PsyrB_22480	COG2384	SAM-dependent methyltransferase
PsyrB_22520	COG1522	sequence-specific DNA binding
PsyrB_22530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PsyrB_22535	COG1960	acyl-CoA dehydrogenase activity
PsyrB_22550	COG0352	thiamine-phosphate diphosphorylase activity
PsyrB_22555	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PsyrB_22570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PsyrB_22575	COG1702	phosphate starvation-inducible protein PhoH
PsyrB_22580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PsyrB_22585	COG4535	Mg2 and Co2 transporter CorC
PsyrB_22590	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PsyrB_22595	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PsyrB_22605	COG0495	leucyl-tRNA aminoacylation
PsyrB_22625	COG2951	lytic endotransglycosylase activity
PsyrB_22630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PsyrB_22635	COG0321	lipoyl(octanoyl) transferase activity
PsyrB_22640	COG2921	Belongs to the UPF0250 family
PsyrB_22645	COG1686	Belongs to the peptidase S11 family
PsyrB_22655	COG2951	lytic endotransglycosylase activity
PsyrB_22660	COG0772	Belongs to the SEDS family
PsyrB_22665	COG0768	penicillin binding
PsyrB_22670	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PsyrB_22680	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PsyrB_22685	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PsyrB_22690	COG2094	Belongs to the DNA glycosylase MPG family
PsyrB_22695	COG0586	Pfam SNARE associated Golgi protein
PsyrB_22725	COG3706	GGDEF domain
PsyrB_22725	COG0745	RESPONSE REGULATOR receiver
PsyrB_22740	COG0023	Translation Initiation Factor
PsyrB_22745	COG1166	arginine decarboxylase activity
PsyrB_22760	COG0534	Mate efflux family protein
PsyrB_22765	COG2373	Large extracellular alpha-helical protein
PsyrB_22775	COG4953	penicillin-binding protein 1C
PsyrB_22795	COG4964	Belongs to the GSP D family
PsyrB_22835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PsyrB_22850	COG2264	protein methyltransferase activity
PsyrB_22860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PsyrB_22870	COG0138	bifunctional purine biosynthesis protein purh
PsyrB_22875	COG0151	Belongs to the GarS family
PsyrB_22885	COG2095	MarC family integral membrane protein
PsyrB_22925	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PsyrB_22935	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
PsyrB_22970	COG0683	leucine binding
PsyrB_22975	COG0559	Belongs to the binding-protein-dependent transport system permease family
PsyrB_22985	COG0411	ABC transporter
PsyrB_22990	COG0410	ABC transporter
PsyrB_22995	COG0829	nickel cation binding
PsyrB_23000	COG0831	urea catabolic process
PsyrB_23015	COG0832	Belongs to the urease beta subunit family
PsyrB_23020	COG0804	urea catabolic process
PsyrB_23025	COG3118	belongs to the thioredoxin family
PsyrB_23040	COG0484	heat shock protein binding
PsyrB_23045	COG0443	Heat shock 70 kDa protein
PsyrB_23060	COG0697	spore germination
PsyrB_23080	COG2982	Protein involved in outer membrane biogenesis
PsyrB_23090	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PsyrB_23095	COG0830	nickel cation binding
PsyrB_23100	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PsyrB_23115	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PsyrB_23125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PsyrB_23130	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PsyrB_23145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PsyrB_23145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PsyrB_23150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PsyrB_23160	COG2264	protein methyltransferase activity
PsyrB_23165	COG3118	belongs to the thioredoxin family
PsyrB_23200	COG3047	cAMP biosynthetic process
PsyrB_23215	COG0668	transmembrane transport
PsyrB_23225	COG0179	Fumarylacetoacetate (FAA) hydrolase
PsyrB_23265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PsyrB_23270	COG0738	Major facilitator superfamily
PsyrB_23280	COG1349	DNA-binding transcription factor activity
PsyrB_23285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PsyrB_23305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PsyrB_23340	COG1653	transport
PsyrB_23345	COG1175	transmembrane transport
PsyrB_23350	COG0395	ABC-type sugar transport system, permease component
PsyrB_23355	COG3842	ATPase activity
PsyrB_23360	COG0584	glycerophosphoryl diester phosphodiesterase
PsyrB_23365	COG0483	inositol monophosphate 1-phosphatase activity
PsyrB_23375	COG0629	single-stranded DNA binding
PsyrB_23380	COG2814	Major facilitator Superfamily
PsyrB_23385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PsyrB_23390	COG2193	ferroxidase activity
PsyrB_23400	COG0203	ribosomal protein L17
PsyrB_23405	COG0202	RNA polymerase activity
PsyrB_23410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PsyrB_23415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PsyrB_23420	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PsyrB_23435	COG0200	Binds to the 23S rRNA
PsyrB_23440	COG1841	ribosomal large subunit assembly
PsyrB_23445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PsyrB_23450	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PsyrB_23455	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PsyrB_23460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PsyrB_23465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PsyrB_23470	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PsyrB_23475	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PsyrB_23480	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PsyrB_23485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PsyrB_23490	COG0255	Belongs to the universal ribosomal protein uL29 family
PsyrB_23495	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PsyrB_23500	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PsyrB_23505	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PsyrB_23510	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PsyrB_23515	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PsyrB_23520	COG0089	rRNA binding
PsyrB_23525	COG0088	Forms part of the polypeptide exit tunnel
PsyrB_23530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PsyrB_23535	COG0051	transcription antitermination factor activity, RNA binding
PsyrB_23540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PsyrB_23545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PsyrB_23550	COG0049	tRNA binding
PsyrB_23555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PsyrB_23565	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PsyrB_23570	COG0085	RNA polymerase activity
PsyrB_23580	COG0222	ribosome binding
PsyrB_23585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PsyrB_23595	COG0081	regulation of translation
PsyrB_23600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PsyrB_23640	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PsyrB_23680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PsyrB_23685	COG0739	heme binding
PsyrB_23690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PsyrB_23695	COG0316	Belongs to the HesB IscA family
PsyrB_23700	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PsyrB_23715	COG4221	oxidoreductase activity
PsyrB_23720	COG0537	adenosine 5'-monophosphoramidase activity
PsyrB_23725	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
PsyrB_23730	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PsyrB_23735	COG1765	OsmC-like protein
PsyrB_23750	COG0134	indole-3-glycerol-phosphate synthase activity
PsyrB_23755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PsyrB_23760	COG0512	Glutamine amidotransferase of anthranilate synthase
PsyrB_23775	COG3179	chitinase
PsyrB_23795	COG3299	homolog of phage Mu protein gp47
PsyrB_23800	COG4381	Mu-like prophage protein gp46
PsyrB_23840	COG4386	tail sheath protein
PsyrB_23900	COG2801	Transposase and inactivated derivatives
PsyrB_23910	COG0546	phosphoglycolate phosphatase activity
PsyrB_23915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PsyrB_23925	COG1176	ABC-type spermidine putrescine transport system, permease component I
PsyrB_23935	COG3842	ATPase activity
PsyrB_23940	COG2197	response regulator
PsyrB_23945	COG4585	Histidine kinase
PsyrB_23955	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PsyrB_23960	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PsyrB_23965	COG3178	'Phosphotransferase
PsyrB_23970	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PsyrB_23975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PsyrB_23980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PsyrB_23985	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PsyrB_23990	COG2967	ApaG domain
PsyrB_23995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PsyrB_24000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PsyrB_24005	COG2766	serine protein kinase
PsyrB_24010	COG2718	Belongs to the UPF0229 family
PsyrB_24015	COG2719	SpoVR family
PsyrB_24020	COG0617	tRNA 3'-terminal CCA addition
PsyrB_24025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PsyrB_24030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PsyrB_24035	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PsyrB_24040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PsyrB_24045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PsyrB_24050	COG0358	DNA primase activity
PsyrB_24055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PsyrB_24080	COG0582	viral genome integration into host DNA
PsyrB_24100	COG4974	Belongs to the 'phage' integrase family
PsyrB_24130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PsyrB_24135	COG2116	formate transmembrane transporter activity
PsyrB_24165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PsyrB_24170	COG1025	Belongs to the peptidase M16 family
PsyrB_24175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PsyrB_24180	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
PsyrB_24190	COG0535	radical SAM domain protein
PsyrB_24210	COG1960	acyl-CoA dehydrogenase activity
PsyrB_24215	COG3706	GGDEF domain
PsyrB_24220	COG1960	acyl-CoA dehydrogenase activity
PsyrB_24240	COG2226	methyltransferase
PsyrB_24240	COG1073	alpha beta
PsyrB_24245	COG0156	8-amino-7-oxononanoate synthase activity
PsyrB_24250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PsyrB_24255	COG1040	competence protein
PsyrB_24260	COG2005	Transcriptional regulator
PsyrB_24260	COG3585	molybdate ion transport
PsyrB_24270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PsyrB_24275	COG3842	ATPase activity
PsyrB_24280	COG1177	transmembrane transport
PsyrB_24285	COG1175	transmembrane transport
PsyrB_24300	COG1609	Transcriptional regulator
PsyrB_24305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PsyrB_24320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PsyrB_24335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PsyrB_24375	COG0517	IMP dehydrogenase activity
PsyrB_24375	COG4175	Glycine betaine
PsyrB_24380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PsyrB_24425	COG2801	Transposase and inactivated derivatives
PsyrB_24450	COG0204	Acyl-transferase
PsyrB_24460	COG2801	Transposase and inactivated derivatives
PsyrB_24475	COG0625	glutathione transferase activity
PsyrB_24490	COG3712	iron ion homeostasis
PsyrB_24495	COG1595	DNA-templated transcription, initiation
PsyrB_24500	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PsyrB_24505	COG1012	belongs to the aldehyde dehydrogenase family
PsyrB_24510	COG1309	transcriptional regulator
PsyrB_24515	COG1160	GTP binding
PsyrB_24535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PsyrB_24540	COG2022	thiamine diphosphate biosynthetic process
PsyrB_24550	COG2363	Small membrane protein
PsyrB_24555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PsyrB_24565	COG2177	Part of the ABC transporter FtsEX involved in
PsyrB_24570	COG2884	Cell division ATP-binding protein ftsE
PsyrB_24575	COG0552	protein localization to endoplasmic reticulum
PsyrB_24580	COG0612	Peptidase, M16
PsyrB_24585	COG0612	Peptidase, M16
PsyrB_24590	COG0742	ribosomal rna small subunit methyltransferase
PsyrB_24595	COG0429	hydrolase of the alpha beta-hydrolase fold
PsyrB_24605	COG1309	transcriptional regulator
PsyrB_24610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PsyrB_24615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PsyrB_24625	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PsyrB_24630	COG1639	'signal transduction protein
PsyrB_24635	COG0693	protein deglycase activity
PsyrB_24640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PsyrB_24665	COG0477	Major facilitator Superfamily
PsyrB_24675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PsyrB_24680	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PsyrB_24700	COG1017	nitric oxide dioxygenase activity
PsyrB_24700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PsyrB_24705	COG4638	Rieske (2fe-2S)
PsyrB_24710	COG3469	chitinase activity
PsyrB_24730	COG0247	lactate metabolic process
PsyrB_24730	COG2181	nitrate reductase activity
PsyrB_24735	COG0446	pyridine nucleotide-disulphide oxidoreductase
PsyrB_24735	COG1902	pentaerythritol trinitrate reductase activity
PsyrB_24780	COG0126	phosphoglycerate kinase activity
PsyrB_24790	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PsyrB_24800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PsyrB_24805	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PsyrB_24820	COG0642	Histidine kinase
PsyrB_24850	COG3209	COG3209 Rhs family protein
PsyrB_24860	COG3209	COG3209 Rhs family protein
PsyrB_24870	COG3209	COG3209 Rhs family protein
PsyrB_24930	COG1349	DNA-binding transcription factor activity
PsyrB_24940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PsyrB_24940	COG0301	tRNA thio-modification
PsyrB_24965	COG3852	Histidine kinase
PsyrB_24975	COG0667	Aldo Keto reductase
PsyrB_24980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PsyrB_24990	COG4771	TonB-dependent receptor
PsyrB_24995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PsyrB_25000	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PsyrB_25010	COG4176	ABC-type proline glycine betaine transport system permease component
PsyrB_25015	COG0517	IMP dehydrogenase activity
PsyrB_25015	COG4175	Glycine betaine
PsyrB_25020	COG2986	histidine ammonia-lyase
PsyrB_25025	COG2986	histidine ammonia-lyase
PsyrB_25035	COG1228	amidohydrolase
PsyrB_25050	COG0789	Transcriptional regulator
PsyrB_25065	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PsyrB_25070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PsyrB_25075	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
PsyrB_25080	COG0494	nUDIX hydrolase
PsyrB_25095	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PsyrB_25110	COG0179	Fumarylacetoacetate (FAA) hydrolase
PsyrB_25115	COG0277	FAD linked oxidase domain protein
PsyrB_25120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PsyrB_25155	COG1177	transmembrane transport
PsyrB_25160	COG1176	ABC-type spermidine putrescine transport system, permease component I
PsyrB_25165	COG3842	ATPase activity
PsyrB_25185	COG0174	glutamine synthetase
PsyrB_25195	COG0174	glutamine synthetase
PsyrB_25225	COG1116	anion transmembrane transporter activity
PsyrB_25230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PsyrB_25235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PsyrB_25240	COG0450	alkyl hydroperoxide reductase
PsyrB_25255	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PsyrB_25260	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PsyrB_25270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PsyrB_25275	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PsyrB_25280	COG4942	peptidase
PsyrB_25285	COG0793	Belongs to the peptidase S41A family
PsyrB_25290	COG2861	carbohydrate metabolic process
PsyrB_25315	COG0107	imidazoleglycerol-phosphate synthase activity
PsyrB_25320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PsyrB_25330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PsyrB_25335	COG0131	Imidazoleglycerol-phosphate dehydratase
PsyrB_25340	COG1448	Aminotransferase
PsyrB_25355	COG1194	a g-specific adenine glycosylase
PsyrB_25360	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PsyrB_25405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PsyrB_25410	COG4215	(ABC) transporter
PsyrB_25435	COG0484	heat shock protein binding
PsyrB_25595	COG4695	Portal protein
PsyrB_25635	COG4584	PFAM Integrase catalytic
PsyrB_25640	COG1484	DNA-dependent DNA replication
PsyrB_25660	COG0431	NADPH-dependent FMN reductase
PsyrB_25670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PsyrB_25675	COG0640	Transcriptional regulator
PsyrB_25830	COG2957	Belongs to the agmatine deiminase family
PsyrB_25840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PsyrB_25870	COG1218	3'(2'),5'-bisphosphate nucleotidase
PsyrB_25875	COG0494	nUDIX hydrolase
PsyrB_25880	COG1011	Hydrolase
PsyrB_25885	COG1652	LysM domain
PsyrB_25890	COG0583	DNA-binding transcription factor activity
PsyrB_25895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PsyrB_25900	COG0243	molybdopterin cofactor binding
PsyrB_25985	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PsyrB_25985	COG2885	chlorophyll binding
PsyrB_26020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PsyrB_26075	COG3501	Rhs element vgr protein
PsyrB_26090	COG3209	COG3209 Rhs family protein
PsyrB_26110	COG3209	COG3209 Rhs family protein
PsyrB_26180	COG0668	transmembrane transport
PsyrB_26195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PsyrB_26200	COG0667	Aldo Keto reductase
PsyrB_26205	COG1802	Transcriptional regulator
PsyrB_26220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PsyrB_26270	COG1960	acyl-CoA dehydrogenase activity
PsyrB_26275	COG0583	DNA-binding transcription factor activity
PsyrB_26280	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PsyrB_26285	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PsyrB_26290	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PsyrB_26295	COG0427	acetyl-CoA hydrolase
PsyrB_26350	COG3161	chorismate lyase activity
PsyrB_26355	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PsyrB_26370	COG1253	flavin adenine dinucleotide binding
PsyrB_26375	COG0739	heme binding
PsyrB_26385	COG0704	Plays a role in the regulation of phosphate uptake
PsyrB_26390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PsyrB_26395	COG0573	inorganic phosphate transmembrane transporter activity
PsyrB_26400	COG0573	inorganic phosphate transmembrane transporter activity
PsyrB_26415	COG1607	acyl-coa hydrolase
PsyrB_26450	COG0583	DNA-binding transcription factor activity
PsyrB_26460	COG1027	Aspartate ammonia-lyase
PsyrB_26465	COG1115	amino acid carrier protein
PsyrB_26470	COG0252	asparaginase activity
PsyrB_26475	COG3781	membrane
PsyrB_26480	COG2391	methyltransferase activity
PsyrB_26505	COG0511	ligase activity, forming carbon-carbon bonds
PsyrB_26505	COG5016	pyruvate
PsyrB_26510	COG0439	Biotin carboxylase
PsyrB_26515	COG0583	DNA-binding transcription factor activity
PsyrB_26530	COG1737	Transcriptional regulator
PsyrB_26535	COG0210	DNA helicase
PsyrB_26550	COG4651	solute:proton antiporter activity
PsyrB_26550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PsyrB_26555	COG1607	acyl-coa hydrolase
PsyrB_26560	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PsyrB_26570	COG0523	cobalamin synthesis protein
PsyrB_26595	COG0860	N-Acetylmuramoyl-L-alanine amidase
PsyrB_26605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PsyrB_26615	COG2184	nucleotidyltransferase activity
PsyrB_26620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PsyrB_26625	COG2217	Heavy metal translocating P-type atpase
PsyrB_26645	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PsyrB_26655	COG2755	lipolytic protein G-D-S-L family
PsyrB_26655	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PsyrB_26660	COG4566	intracellular signal transduction
PsyrB_26665	COG4191	Histidine kinase
PsyrB_26670	COG1116	anion transmembrane transporter activity
PsyrB_26680	COG0840	transmembrane signaling receptor activity
PsyrB_26695	COG3546	catalase activity
PsyrB_26705	COG3685	Protein conserved in bacteria
PsyrB_26720	COG2890	protein-(glutamine-N5) methyltransferase activity
PsyrB_26740	COG0463	Glycosyl transferase, family 2
PsyrB_26745	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PsyrB_26745	COG3952	Lipid A Biosynthesis
PsyrB_26750	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PsyrB_26755	COG3204	pilus organization
PsyrB_26795	COG3501	Rhs element vgr protein
PsyrB_26810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PsyrB_26815	COG1349	DNA-binding transcription factor activity
PsyrB_26820	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PsyrB_26825	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PsyrB_26830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PsyrB_26835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PsyrB_26840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PsyrB_26845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PsyrB_26850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PsyrB_26860	COG0356	it plays a direct role in the translocation of protons across the membrane
PsyrB_26865	COG3312	ion transport
PsyrB_26870	COG1475	DNA binding
PsyrB_26875	COG1192	Involved in chromosome partitioning
PsyrB_26880	COG0357	Ribosomal RNA small subunit methyltransferase G
PsyrB_26885	COG0445	tRNA wobble uridine modification
PsyrB_26890	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PsyrB_26895	COG0706	membrane insertase activity
PsyrB_26900	COG0594	ribonuclease P activity
PsyrB_26905	COG0230	Belongs to the bacterial ribosomal protein bL34 family