locus-tag	class	description
AOC03_00010	COG0308	aminopeptidase N
AOC03_00015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOC03_00020	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOC03_00025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AOC03_00040	COG0019	diaminopimelate decarboxylase activity
AOC03_00055	COG2314	TM2 domain
AOC03_00095	COG2020	methyltransferase activity
AOC03_00105	COG1742	UPF0060 membrane protein
AOC03_00115	COG0802	atpase or kinase
AOC03_00120	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AOC03_00125	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AOC03_00130	COG1923	regulation of RNA biosynthetic process
AOC03_00140	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AOC03_00150	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AOC03_00155	COG1137	ATPase activity
AOC03_00170	COG0772	Belongs to the SEDS family
AOC03_00190	COG0612	Peptidase, M16
AOC03_00195	COG0552	protein localization to endoplasmic reticulum
AOC03_00200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOC03_00205	COG0217	transcriptional regulatory protein
AOC03_00210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOC03_00215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOC03_00220	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AOC03_00230	COG0513	Belongs to the DEAD box helicase family
AOC03_00250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOC03_00255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOC03_00260	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AOC03_00280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AOC03_00285	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOC03_00290	COG0305	Participates in initiation and elongation during chromosome replication
AOC03_00300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AOC03_00305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AOC03_00310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOC03_00320	COG1960	acyl-CoA dehydrogenase activity
AOC03_00325	COG1960	acyl-CoA dehydrogenase activity
AOC03_00335	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOC03_00340	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AOC03_00345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AOC03_00355	COG0668	transmembrane transport
AOC03_00365	COG0134	indole-3-glycerol-phosphate synthase activity
AOC03_00370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOC03_00375	COG0512	Glutamine amidotransferase of anthranilate synthase
AOC03_00395	COG1704	LemA family
AOC03_00400	COG0501	Belongs to the peptidase M48B family
AOC03_00415	COG4166	transmembrane transport
AOC03_00425	COG4174	ABC transporter (Permease)
AOC03_00430	COG4239	(ABC) transporter, permease
AOC03_00435	COG4172	Belongs to the ABC transporter superfamily
AOC03_00440	COG0302	gtp cyclohydrolase
AOC03_00455	COG0471	metal ion transport
AOC03_00460	COG2850	peptidyl-arginine hydroxylation
AOC03_00475	COG0482	sulfurtransferase activity
AOC03_00480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AOC03_00485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AOC03_00495	COG0445	tRNA wobble uridine modification
AOC03_00510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOC03_00515	COG0583	DNA-binding transcription factor activity
AOC03_00520	COG2807	transmembrane transport
AOC03_00525	COG2890	protein-(glutamine-N5) methyltransferase activity
AOC03_00535	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOC03_00545	COG1522	sequence-specific DNA binding
AOC03_00550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOC03_00560	COG0439	Biotin carboxylase
AOC03_00565	COG0511	ligase activity, forming carbon-carbon bonds
AOC03_00570	COG0534	Mate efflux family protein
AOC03_00580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOC03_00595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOC03_00620	COG2130	NADP-dependent
AOC03_00625	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AOC03_00655	COG0438	transferase activity, transferring glycosyl groups
AOC03_00665	COG0438	transferase activity, transferring glycosyl groups
AOC03_00670	COG0438	transferase activity, transferring glycosyl groups
AOC03_00690	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AOC03_00695	COG0616	signal peptide processing
AOC03_00715	COG0390	transport system, permease component
AOC03_00720	COG3842	ATPase activity
AOC03_00725	COG0824	Thioesterase
AOC03_00730	COG0708	Exodeoxyribonuclease III
AOC03_00735	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOC03_00745	COG1760	l-serine dehydratase
AOC03_00750	COG2233	PERMEase
AOC03_00770	COG1773	rubredoxin
AOC03_00775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AOC03_00780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOC03_00790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOC03_00795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOC03_00805	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOC03_00820	COG3189	MarR family transcriptional regulator
AOC03_00825	COG1045	serine acetyltransferase
AOC03_00850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOC03_00855	COG1115	amino acid carrier protein
AOC03_00860	COG1012	belongs to the aldehyde dehydrogenase family
AOC03_00865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOC03_00870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOC03_00875	COG3938	Belongs to the proline racemase family
AOC03_00885	COG0405	Gamma-glutamyltransferase
AOC03_00905	COG0745	RESPONSE REGULATOR receiver
AOC03_00910	COG2205	protein histidine kinase activity
AOC03_00940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOC03_00945	COG0581	inorganic phosphate transmembrane transporter activity
AOC03_00960	COG1902	pentaerythritol trinitrate reductase activity
AOC03_00960	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOC03_00965	COG0642	Histidine kinase
AOC03_00970	COG0745	RESPONSE REGULATOR receiver
AOC03_00990	COG0745	RESPONSE REGULATOR receiver
AOC03_00995	COG0642	Histidine kinase
AOC03_01010	COG1477	protein flavinylation
AOC03_01025	COG0586	Pfam SNARE associated Golgi protein
AOC03_01030	COG3122	Protein conserved in bacteria
AOC03_01040	COG0281	malic enzyme
AOC03_01050	COG1518	maintenance of DNA repeat elements
AOC03_01050	COG1468	defense response to virus
AOC03_01075	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AOC03_01080	COG1074	ATP-dependent DNA helicase activity
AOC03_01085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOC03_01100	COG1160	GTP binding
AOC03_01110	COG2233	PERMEase
AOC03_01120	COG2079	MmgE PrpD family protein
AOC03_01140	COG2828	Protein conserved in bacteria
AOC03_01150	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOC03_01155	COG0372	Belongs to the citrate synthase family
AOC03_01160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOC03_01170	COG0583	DNA-binding transcription factor activity
AOC03_01180	COG0564	pseudouridine synthase activity
AOC03_01185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOC03_01190	COG1187	pseudouridine synthase activity
AOC03_01210	COG2066	Belongs to the glutaminase family
AOC03_01215	COG1027	Aspartate ammonia-lyase
AOC03_01220	COG1301	dicarboxylic acid transport
AOC03_01225	COG0583	DNA-binding transcription factor activity
AOC03_01230	COG0625	glutathione transferase activity
AOC03_01240	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AOC03_01335	COG1525	nuclease
AOC03_01340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOC03_01355	COG1201	RNA secondary structure unwinding
AOC03_01465	COG0500	methyltransferase
AOC03_01490	COG2808	Putative FMN-binding domain
AOC03_01500	COG3813	Protein conserved in bacteria
AOC03_01510	COG0560	Phosphoserine phosphatase
AOC03_01515	COG0697	spore germination
AOC03_01535	COG0384	phenazine biosynthesis protein PhzF
AOC03_01555	COG1309	transcriptional regulator
AOC03_01560	COG1335	isochorismatase
AOC03_01565	COG0519	Catalyzes the synthesis of GMP from XMP
AOC03_01565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOC03_01585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOC03_01630	COG0582	viral genome integration into host DNA
AOC03_01645	COG3228	Belongs to the MtfA family
AOC03_01650	COG2308	Evidence 4 Homologs of previously reported genes of
AOC03_01670	COG0513	Belongs to the DEAD box helicase family
AOC03_01680	COG0625	glutathione transferase activity
AOC03_01685	COG0477	Major facilitator Superfamily
AOC03_01715	COG4208	sulfate ABC transporter
AOC03_01720	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AOC03_01725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AOC03_01730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AOC03_01740	COG2046	Belongs to the sulfate adenylyltransferase family
AOC03_01745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOC03_01755	COG0175	sulfate reduction
AOC03_01760	COG1648	precorrin-2 dehydrogenase activity
AOC03_01760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOC03_01765	COG0420	3'-5' exonuclease activity
AOC03_01770	COG0419	ATPase involved in DNA repair
AOC03_01790	COG0151	Belongs to the GarS family
AOC03_01795	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOC03_01805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOC03_01815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOC03_01820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOC03_01830	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AOC03_01850	COG2207	Transcriptional regulator
AOC03_01850	COG4753	response regulator
AOC03_01855	COG4191	Histidine kinase
AOC03_01865	COG1643	Atp-dependent helicase
AOC03_01875	COG0402	S-adenosylhomocysteine deaminase activity
AOC03_01885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOC03_01890	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AOC03_01905	COG2252	PERMEase
AOC03_01925	COG0823	Involved in the tonB-independent uptake of proteins
AOC03_01935	COG1233	COG1233 Phytoene dehydrogenase and related
AOC03_01970	COG0564	pseudouridine synthase activity
AOC03_02010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOC03_02025	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOC03_02030	COG0633	Ferredoxin
AOC03_02035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOC03_02040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOC03_02050	COG1388	LysM domain
AOC03_02050	COG0741	lytic transglycosylase activity
AOC03_02050	COG1388	LysM domain
AOC03_02050	COG0741	lytic transglycosylase activity
AOC03_02060	COG4536	flavin adenine dinucleotide binding
AOC03_02065	COG1862	Preprotein translocase
AOC03_02075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOC03_02080	COG0534	Mate efflux family protein
AOC03_02105	COG0167	dihydroorotate dehydrogenase activity
AOC03_02140	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AOC03_02155	COG1570	exodeoxyribonuclease VII activity
AOC03_02175	COG4175	Glycine betaine
AOC03_02180	COG4176	ABC-type proline glycine betaine transport system permease component
AOC03_02190	COG0321	lipoyl(octanoyl) transferase activity
AOC03_02210	COG4221	oxidoreductase activity
AOC03_02220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOC03_02225	COG0537	adenosine 5'-monophosphoramidase activity
AOC03_02235	COG0129	dihydroxy-acid dehydratase activity
AOC03_02250	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AOC03_02265	COG2205	protein histidine kinase activity
AOC03_02265	COG0784	Response regulator, receiver
AOC03_02270	COG1160	GTP binding
AOC03_02275	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOC03_02285	COG0124	histidyl-tRNA synthetase
AOC03_02290	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AOC03_02305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AOC03_02310	COG0105	UTP biosynthetic process
AOC03_02320	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AOC03_02325	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AOC03_02335	COG0598	Magnesium transport protein CorA
AOC03_02340	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AOC03_02360	COG1619	proteins homologs of microcin C7 resistance protein MccF
AOC03_02365	COG3339	Conserved Protein
AOC03_02380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOC03_02395	COG2878	Part of a membrane complex involved in electron transport
AOC03_02400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOC03_02405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AOC03_02430	COG3123	guanosine phosphorylase activity
AOC03_02455	COG0505	Belongs to the CarA family
AOC03_02460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AOC03_02465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOC03_02480	COG1012	belongs to the aldehyde dehydrogenase family
AOC03_02485	COG0069	glutamate synthase activity
AOC03_02490	COG3698	Phosphodiester glycosidase
AOC03_02495	COG0012	GTP binding
AOC03_02535	COG0084	hydrolase, TatD family'
AOC03_02550	COG1720	tRNA m6t6A37 methyltransferase activity
AOC03_02570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOC03_02575	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AOC03_02600	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AOC03_02610	COG0473	3-isopropylmalate dehydrogenase activity
AOC03_02620	COG0066	3-isopropylmalate dehydratase activity
AOC03_02625	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AOC03_02630	COG0583	DNA-binding transcription factor activity
AOC03_02635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOC03_02655	COG0723	plastoquinol--plastocyanin reductase activity
AOC03_02660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOC03_02665	COG2857	Cytochrome c1
AOC03_02670	COG0625	glutathione transferase activity
AOC03_02675	COG2969	positive regulation of protein catabolic process
AOC03_02680	COG0717	Belongs to the dCTP deaminase family
AOC03_02685	COG0489	protein tyrosine kinase activity
AOC03_02690	COG2239	Acts as a magnesium transporter
AOC03_02695	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_02700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOC03_02700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOC03_02735	COG1017	nitric oxide dioxygenase activity
AOC03_02735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOC03_02755	COG0431	NADPH-dependent FMN reductase
AOC03_02775	COG1451	nucleotide metabolic process
AOC03_02790	COG0386	Belongs to the glutathione peroxidase family
AOC03_02795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOC03_02800	COG0436	Aminotransferase
AOC03_02830	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOC03_02835	COG2255	four-way junction helicase activity
AOC03_02840	COG0632	four-way junction helicase activity
AOC03_02845	COG0191	fructose-bisphosphate aldolase activity
AOC03_02855	COG0126	phosphoglycerate kinase activity
AOC03_02860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOC03_02865	COG0352	thiamine-phosphate diphosphorylase activity
AOC03_02870	COG1686	Belongs to the peptidase S11 family
AOC03_02895	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AOC03_02905	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AOC03_02920	COG0450	alkyl hydroperoxide reductase
AOC03_02935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOC03_02945	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOC03_02950	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AOC03_02955	COG1162	GTPase activity
AOC03_02970	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AOC03_02975	COG0563	adenylate kinase activity
AOC03_03005	COG0768	penicillin binding
AOC03_03010	COG0742	ribosomal rna small subunit methyltransferase
AOC03_03015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AOC03_03020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOC03_03035	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AOC03_03040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AOC03_03055	COG0438	transferase activity, transferring glycosyl groups
AOC03_03060	COG1442	glycosyl transferase family 8
AOC03_03060	COG1216	Glycosyl transferase, family 2
AOC03_03075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOC03_03085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOC03_03090	COG0438	transferase activity, transferring glycosyl groups
AOC03_03130	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AOC03_03175	COG2095	MarC family integral membrane protein
AOC03_03195	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOC03_03200	COG2431	L-lysine efflux transmembrane transporter activity
AOC03_03210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOC03_03215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOC03_03220	COG1702	phosphate starvation-inducible protein PhoH
AOC03_03225	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AOC03_03230	COG0668	transmembrane transport
AOC03_03245	COG1007	ATP synthesis coupled electron transport
AOC03_03250	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOC03_03260	COG0713	ATP synthesis coupled electron transport
AOC03_03265	COG0839	Belongs to the complex I subunit 6 family
AOC03_03270	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOC03_03275	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AOC03_03285	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AOC03_03295	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOC03_03295	COG0649	NAD binding
AOC03_03300	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOC03_03305	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOC03_03315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AOC03_03320	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AOC03_03340	COG1538	Outer membrane efflux protein
AOC03_03355	COG0210	DNA helicase
AOC03_03360	COG2239	Acts as a magnesium transporter
AOC03_03365	COG0756	dUTP diphosphatase activity
AOC03_03370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOC03_03375	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AOC03_03380	COG1393	Belongs to the ArsC family
AOC03_03385	COG0495	leucyl-tRNA aminoacylation
AOC03_03400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOC03_03405	COG1136	(ABC) transporter
AOC03_03405	COG0577	efflux transmembrane transporter activity
AOC03_03425	COG0753	catalase activity
AOC03_03490	COG1183	phosphatidylcholine synthase activity
AOC03_03495	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AOC03_03505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOC03_03520	COG2975	iron-sulfur cluster assembly
AOC03_03530	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AOC03_03535	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AOC03_03540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AOC03_03545	COG3022	response to hydroperoxide
AOC03_03555	COG0459	protein refolding
AOC03_03560	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AOC03_03575	COG1295	ribonuclease BN
AOC03_03595	COG0540	Belongs to the ATCase OTCase family
AOC03_03600	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AOC03_03605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOC03_03620	COG1278	Cold shock
AOC03_03630	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AOC03_03635	COG0440	acetolactate synthase activity
AOC03_03640	COG0028	Belongs to the TPP enzyme family
AOC03_03650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AOC03_03650	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AOC03_03655	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AOC03_03660	COG1652	LysM domain
AOC03_03670	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_03680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AOC03_03690	COG3101	peptidyl-lysine hydroxylation
AOC03_03695	COG0009	L-threonylcarbamoyladenylate synthase
AOC03_03700	COG0203	ribosomal protein L17
AOC03_03705	COG0202	RNA polymerase activity
AOC03_03710	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AOC03_03715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AOC03_03720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AOC03_03725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AOC03_03735	COG0200	Binds to the 23S rRNA
AOC03_03740	COG1841	ribosomal large subunit assembly
AOC03_03745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AOC03_03750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AOC03_03755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AOC03_03760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AOC03_03765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AOC03_03770	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AOC03_03775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AOC03_03780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AOC03_03785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AOC03_03790	COG0255	Belongs to the universal ribosomal protein uL29 family
AOC03_03795	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AOC03_03800	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AOC03_03805	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AOC03_03810	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AOC03_03815	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AOC03_03820	COG0089	rRNA binding
AOC03_03825	COG0088	Forms part of the polypeptide exit tunnel
AOC03_03830	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AOC03_03835	COG0051	transcription antitermination factor activity, RNA binding
AOC03_03840	COG1530	ribonuclease E activity
AOC03_03845	COG0424	maF-like protein
AOC03_03855	COG1792	Involved in formation and maintenance of cell shape
AOC03_03860	COG1077	Cell shape determining protein MreB Mrl
AOC03_03865	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOC03_03870	COG0154	amidase activity
AOC03_03875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOC03_03905	COG0285	dihydrofolate synthase activity
AOC03_03910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AOC03_03915	COG0159	tryptophan synthase activity
AOC03_03925	COG0133	tryptophan synthase activity
AOC03_03935	COG0415	Belongs to the DNA photolyase family
AOC03_03945	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOC03_03955	COG0742	ribosomal rna small subunit methyltransferase
AOC03_03960	COG1968	undecaprenyl-diphosphatase activity
AOC03_03965	COG1214	PFAM Peptidase M22, glycoprotease
AOC03_03975	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOC03_03985	COG0829	nickel cation binding
AOC03_03990	COG0831	urea catabolic process
AOC03_03995	COG0832	Belongs to the urease beta subunit family
AOC03_04000	COG0804	urea catabolic process
AOC03_04010	COG0830	nickel cation binding
AOC03_04015	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AOC03_04030	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AOC03_04035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AOC03_04055	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOC03_04075	COG0326	Molecular chaperone. Has ATPase activity
AOC03_04090	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AOC03_04095	COG0194	GDP metabolic process
AOC03_04100	COG1758	RNA polymerase activity
AOC03_04105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOC03_04115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOC03_04135	COG0475	glutathione-regulated potassium exporter activity
AOC03_04135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOC03_04145	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AOC03_04150	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AOC03_04155	COG2137	regulation of response to DNA damage stimulus
AOC03_04160	COG0471	metal ion transport
AOC03_04175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AOC03_04180	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOC03_04185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOC03_04190	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AOC03_04215	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AOC03_04230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOC03_04235	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOC03_04240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOC03_04245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AOC03_04250	COG0189	ligase activity
AOC03_04255	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AOC03_04275	COG3023	N-Acetylmuramoyl-L-alanine amidase
AOC03_04295	COG1247	-acetyltransferase
AOC03_04300	COG0196	riboflavin kinase activity
AOC03_04310	COG0039	L-malate dehydrogenase activity
AOC03_04320	COG1196	nuclear chromosome segregation
AOC03_04320	COG0741	lytic transglycosylase activity
AOC03_04320	COG0739	heme binding
AOC03_04325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOC03_04335	COG1690	Belongs to the RtcB family
AOC03_04340	COG1280	lysine exporter protein (LysE YggA)
AOC03_04345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOC03_04350	COG3079	Belongs to the UPF0149 family
AOC03_04370	COG0751	glycine-tRNA ligase activity
AOC03_04375	COG0752	glycyl-tRNA synthetase alpha subunit
AOC03_04380	COG1983	PspC domain protein
AOC03_04405	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_04415	COG4783	chaperone-mediated protein folding
AOC03_04420	COG0271	Belongs to the BolA IbaG family
AOC03_04435	COG3118	belongs to the thioredoxin family
AOC03_04450	COG0640	Transcriptional regulator
AOC03_04455	COG0659	secondary active sulfate transmembrane transporter activity
AOC03_04465	COG3453	Protein conserved in bacteria
AOC03_04465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOC03_04470	COG3634	alkyl hydroperoxide reductase activity
AOC03_04480	COG0450	alkyl hydroperoxide reductase
AOC03_04485	COG0583	DNA-binding transcription factor activity
AOC03_04520	COG0204	Acyl-transferase
AOC03_04540	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AOC03_04545	COG3038	cytochrome b561
AOC03_04555	COG2201	protein-glutamate methylesterase activity
AOC03_04565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOC03_04570	COG0840	transmembrane signaling receptor activity
AOC03_04595	COG0745	RESPONSE REGULATOR receiver
AOC03_04600	COG2205	protein histidine kinase activity
AOC03_04605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOC03_04610	COG2011	ABC-type metal ion transport system permease component
AOC03_04615	COG1464	Belongs to the NlpA lipoprotein family
AOC03_04620	COG0402	S-adenosylhomocysteine deaminase activity
AOC03_04625	COG2814	Major facilitator Superfamily
AOC03_04630	COG0656	L-ascorbic acid biosynthetic process
AOC03_04635	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AOC03_04655	COG4133	protoheme IX ABC transporter activity
AOC03_04670	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOC03_04680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOC03_04685	COG2003	Belongs to the UPF0758 family
AOC03_04690	COG1960	acyl-CoA dehydrogenase activity
AOC03_04695	COG0730	response to heat
AOC03_04700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOC03_04740	COG0583	DNA-binding transcription factor activity
AOC03_04750	COG1278	Cold shock
AOC03_04755	COG2832	Protein of unknown function (DUF454)
AOC03_04775	COG0525	valine-tRNA ligase activity
AOC03_04785	COG0393	Putative heavy-metal-binding
AOC03_04820	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AOC03_04840	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AOC03_04845	COG0318	PFAM AMP-dependent synthetase and ligase
AOC03_04850	COG0318	PFAM AMP-dependent synthetase and ligase
AOC03_04855	COG2304	oxidoreductase activity
AOC03_04875	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AOC03_04885	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_04890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AOC03_04905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AOC03_04910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AOC03_04935	COG0443	Heat shock 70 kDa protein
AOC03_04945	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AOC03_04950	COG0085	RNA polymerase activity
AOC03_04955	COG0222	ribosome binding
AOC03_04960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AOC03_04965	COG0081	regulation of translation
AOC03_04970	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AOC03_04990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AOC03_04995	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOC03_05000	COG0049	tRNA binding
AOC03_05005	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AOC03_05020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOC03_05025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOC03_05030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOC03_05035	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOC03_05040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AOC03_05060	COG0792	nuclease activity
AOC03_05070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOC03_05080	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AOC03_05085	COG1056	cytidyltransferase-related domain
AOC03_05085	COG1051	belongs to the nudix hydrolase family
AOC03_05100	COG0254	rRNA binding
AOC03_05125	COG4942	peptidase
AOC03_05140	COG1490	D-aminoacyl-tRNA deacylase activity
AOC03_05145	COG0688	phosphatidylethanolamine metabolic process
AOC03_05155	COG0183	Belongs to the thiolase family
AOC03_05160	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOC03_05160	COG1024	Enoyl-CoA hydratase
AOC03_05165	COG0142	geranyltranstransferase activity
AOC03_05185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOC03_05190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AOC03_05195	COG0544	peptidyl-prolyl cis-trans isomerase activity
AOC03_05200	COG0740	serine-type endopeptidase activity
AOC03_05205	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AOC03_05230	COG0018	arginyl-trna synthetase
AOC03_05240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOC03_05250	COG4106	trans-aconitate 2-methyltransferase activity
AOC03_05255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOC03_05260	COG0500	methyltransferase
AOC03_05265	COG2951	lytic endotransglycosylase activity
AOC03_05280	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOC03_05290	COG0644	oxidoreductase
AOC03_05290	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AOC03_05295	COG3162	membrane
AOC03_05310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOC03_05365	COG4221	oxidoreductase activity
AOC03_05385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOC03_05390	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AOC03_05395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOC03_05410	COG3104	oligopeptide transport
AOC03_05425	COG4535	Mg2 and Co2 transporter CorC
AOC03_05435	COG2983	Belongs to the UPF0260 family
AOC03_05440	COG0412	Dienelactone hydrolase
AOC03_05445	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_05455	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AOC03_05470	COG1946	Acyl-CoA thioesterase
AOC03_05475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOC03_05480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOC03_05485	COG0564	pseudouridine synthase activity
AOC03_05490	COG3118	belongs to the thioredoxin family
AOC03_05505	COG2321	neutral zinc metallopeptidase
AOC03_05515	COG0776	regulation of translation
AOC03_05520	COG0072	phenylalanine-tRNA ligase activity
AOC03_05520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOC03_05525	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AOC03_05530	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AOC03_05535	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AOC03_05545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AOC03_05550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOC03_05555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOC03_05570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOC03_05580	COG1765	OsmC-like protein
AOC03_05585	COG0494	nUDIX hydrolase
AOC03_05590	COG1063	alcohol dehydrogenase
AOC03_05600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AOC03_05605	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AOC03_05615	COG0322	excinuclease ABC activity
AOC03_05630	COG0335	large ribosomal subunit rRNA binding
AOC03_05635	COG0336	Belongs to the RNA methyltransferase TrmD family
AOC03_05640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AOC03_05645	COG0228	four-way junction DNA binding
AOC03_05650	COG2205	protein histidine kinase activity
AOC03_05660	COG2205	protein histidine kinase activity
AOC03_05665	COG0745	RESPONSE REGULATOR receiver
AOC03_05670	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AOC03_05675	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AOC03_05680	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AOC03_05685	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AOC03_05690	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOC03_05695	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AOC03_05705	COG0356	it plays a direct role in the translocation of protons across the membrane
AOC03_05725	COG1121	(ABC) transporter
AOC03_05730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOC03_05735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOC03_05740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOC03_05745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOC03_05750	COG0772	Belongs to the SEDS family
AOC03_05755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AOC03_05760	COG0659	secondary active sulfate transmembrane transporter activity
AOC03_05770	COG0347	Belongs to the P(II) protein family
AOC03_05800	COG0583	DNA-binding transcription factor activity
AOC03_05805	COG0288	reversible hydration of carbon dioxide
AOC03_05810	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AOC03_05815	COG2807	transmembrane transport
AOC03_05825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOC03_05830	COG2226	methyltransferase
AOC03_05835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOC03_05840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOC03_05845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOC03_05850	COG0768	penicillin binding
AOC03_05860	COG0275	rRNA processing
AOC03_05865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOC03_05890	COG0697	spore germination
AOC03_05895	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOC03_05910	COG3012	SEC-C Motif Domain Protein
AOC03_05925	COG0121	glutamine amidotransferase
AOC03_05940	COG0107	imidazoleglycerol-phosphate synthase activity
AOC03_05945	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AOC03_05955	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AOC03_05960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AOC03_05965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AOC03_05970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOC03_05985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOC03_05995	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOC03_06010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AOC03_06010	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AOC03_06020	COG0668	transmembrane transport
AOC03_06025	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_06040	COG3150	esterase
AOC03_06155	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOC03_06175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOC03_06190	COG0557	exoribonuclease II activity
AOC03_06205	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AOC03_06210	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AOC03_06230	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AOC03_06235	COG2871	sodium ion transport
AOC03_06240	COG1477	protein flavinylation
AOC03_06250	COG2807	transmembrane transport
AOC03_06255	COG2755	lipolytic protein G-D-S-L family
AOC03_06260	COG0577	efflux transmembrane transporter activity
AOC03_06260	COG1136	(ABC) transporter
AOC03_06270	COG3977	Valine--pyruvate aminotransferase
AOC03_06280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOC03_06285	COG0131	Imidazoleglycerol-phosphate dehydratase
AOC03_06305	COG0546	phosphoglycolate phosphatase activity
AOC03_06310	COG0606	chelatase, subunit chli
AOC03_06325	COG0330	HflC and HflK could
AOC03_06340	COG0156	8-amino-7-oxononanoate synthase activity
AOC03_06345	COG4106	trans-aconitate 2-methyltransferase activity
AOC03_06350	COG0443	Heat shock 70 kDa protein
AOC03_06365	COG1408	metallophosphoesterase
AOC03_06370	COG1408	metallophosphoesterase
AOC03_06375	COG1090	epimerase
AOC03_06380	COG0009	L-threonylcarbamoyladenylate synthase
AOC03_06385	COG0758	DNA mediated transformation
AOC03_06390	COG1652	LysM domain
AOC03_06400	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AOC03_06400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOC03_06410	COG3437	response regulator, receiver
AOC03_06410	COG3850	Histidine kinase
AOC03_06410	COG4999	Histidine kinase
AOC03_06410	COG2205	protein histidine kinase activity
AOC03_06420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOC03_06420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOC03_06425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AOC03_06430	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AOC03_06435	COG0706	membrane insertase activity
AOC03_06440	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AOC03_06445	COG0594	ribonuclease P activity
AOC03_06450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AOC03_06470	COG0187	DNA topoisomerase II activity
AOC03_06475	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AOC03_06480	COG1024	Enoyl-CoA hydratase
AOC03_06485	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AOC03_06495	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AOC03_06500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOC03_06500	COG0519	Catalyzes the synthesis of GMP from XMP
AOC03_06530	COG1794	racemase activity, acting on amino acids and derivatives
AOC03_06535	COG0534	Mate efflux family protein
AOC03_06555	COG0429	hydrolase of the alpha beta-hydrolase fold
AOC03_06560	COG1739	Uncharacterized protein family UPF0029
AOC03_06580	COG0484	heat shock protein binding
AOC03_06585	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AOC03_06595	COG0019	diaminopimelate decarboxylase activity
AOC03_06600	COG0242	peptide deformylase activity
AOC03_06610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOC03_06620	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AOC03_06625	COG2918	glutathione biosynthetic process
AOC03_06635	COG0316	Belongs to the HesB IscA family
AOC03_06640	COG0488	(ABC) transporter
AOC03_06645	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOC03_06650	COG0484	heat shock protein binding
AOC03_06660	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AOC03_06675	COG0795	lipopolysaccharide-transporting ATPase activity
AOC03_06680	COG0795	lipopolysaccharide-transporting ATPase activity
AOC03_06685	COG2813	Specifically methylates the guanine in position
AOC03_06700	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AOC03_06705	COG0425	Belongs to the sulfur carrier protein TusA family
AOC03_06715	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AOC03_06720	COG1678	Uncharacterized ACR, COG1678
AOC03_06725	COG0497	DNA recombination
AOC03_06730	COG3123	guanosine phosphorylase activity
AOC03_06735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOC03_06740	COG0237	dephospho-CoA kinase activity
AOC03_06745	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AOC03_06760	COG0149	triose-phosphate isomerase activity
AOC03_06780	COG0779	Required for maturation of 30S ribosomal subunits
AOC03_06785	COG0195	Participates in both transcription termination and antitermination
AOC03_06785	COG2251	uridine kinase activity
AOC03_06790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AOC03_06795	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AOC03_06800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOC03_06805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AOC03_06810	COG1185	polyribonucleotide nucleotidyltransferase activity
AOC03_06825	COG0339	signal peptide processing
AOC03_06835	COG3568	Endonuclease Exonuclease Phosphatase
AOC03_06860	COG1132	(ABC) transporter
AOC03_06865	COG0697	spore germination
AOC03_06870	COG3588	fructose-bisphosphate aldolase
AOC03_06875	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AOC03_06880	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AOC03_06885	COG0165	Argininosuccinate lyase
AOC03_06945	COG2009	succinate dehydrogenase
AOC03_06950	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AOC03_06955	COG1053	succinate dehydrogenase
AOC03_06960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOC03_06975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOC03_06980	COG0045	succinate-CoA ligase (ADP-forming) activity
AOC03_06985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AOC03_06990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOC03_06995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOC03_07000	COG0166	Belongs to the GPI family
AOC03_07005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AOC03_07015	COG3956	TIGRFAM MazG family protein
AOC03_07020	COG1555	photosystem II stabilization
AOC03_07020	COG1596	polysaccharide export
AOC03_07025	COG0617	tRNA 3'-terminal CCA addition
AOC03_07030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOC03_07035	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AOC03_07040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AOC03_07045	COG1660	Displays ATPase and GTPase activities
AOC03_07060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOC03_07070	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_07075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOC03_07080	COG0523	cobalamin synthesis protein
AOC03_07085	COG0745	RESPONSE REGULATOR receiver
AOC03_07090	COG2183	response to ionizing radiation
AOC03_07100	COG3268	Saccharopine dehydrogenase
AOC03_07105	COG2154	pterin-4-alpha-carbinolamine dehydratase
AOC03_07125	COG0488	(ABC) transporter
AOC03_07135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOC03_07150	COG1960	acyl-CoA dehydrogenase activity
AOC03_07160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOC03_07170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOC03_07190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AOC03_07195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AOC03_07200	COG3263	regulation of cellular component size
AOC03_07205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOC03_07210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOC03_07220	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AOC03_07235	COG2094	Belongs to the DNA glycosylase MPG family
AOC03_07255	COG3237	CsbD-like
AOC03_07265	COG2824	Alkylphosphonate utilization operon protein PhnA
AOC03_07270	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AOC03_07275	COG0248	Ppx GppA phosphatase
AOC03_07285	COG0037	tRNA processing
AOC03_07300	COG0351	phosphomethylpyrimidine kinase
AOC03_07320	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AOC03_07325	COG0193	aminoacyl-tRNA hydrolase activity
AOC03_07335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AOC03_07340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOC03_07355	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AOC03_07370	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AOC03_07390	COG0318	PFAM AMP-dependent synthetase and ligase
AOC03_07395	COG1902	pentaerythritol trinitrate reductase activity
AOC03_07395	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOC03_07415	COG0095	Lipoate-protein ligase
AOC03_07420	COG1902	pentaerythritol trinitrate reductase activity
AOC03_07430	COG2081	HI0933 family
AOC03_07435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOC03_07470	COG0047	phosphoribosylformylglycinamidine synthase activity
AOC03_07470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOC03_07490	COG0519	Catalyzes the synthesis of GMP from XMP
AOC03_07490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOC03_07500	COG3023	N-Acetylmuramoyl-L-alanine amidase
AOC03_07505	COG2258	MOSC domain
AOC03_07515	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AOC03_07520	COG0280	phosphate acetyltransferase
AOC03_07520	COG0857	belongs to the CobB CobQ family
AOC03_07525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOC03_07545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AOC03_07550	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AOC03_07555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOC03_07575	COG2363	Small membrane protein
AOC03_07585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOC03_07585	COG0425	Belongs to the sulfur carrier protein TusA family
AOC03_07600	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AOC03_07615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AOC03_07620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOC03_07625	COG0583	DNA-binding transcription factor activity
AOC03_07630	COG1177	transmembrane transport
AOC03_07635	COG1176	ABC-type spermidine putrescine transport system, permease component I
AOC03_07640	COG3842	ATPase activity
AOC03_07660	COG0408	coproporphyrinogen oxidase activity
AOC03_07670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AOC03_07680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOC03_07685	COG2022	thiamine diphosphate biosynthetic process
AOC03_07695	COG0251	oxidation-reduction process
AOC03_07705	COG1401	restriction endodeoxyribonuclease activity
AOC03_07745	COG2165	general secretion pathway protein
AOC03_07750	COG4232	protein-disulfide reductase activity
AOC03_07835	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AOC03_07840	COG0653	protein targeting
AOC03_07855	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AOC03_07870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOC03_07875	COG2354	Protein conserved in bacteria
AOC03_07880	COG1530	ribonuclease E activity
AOC03_07895	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AOC03_07920	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOC03_07925	COG0735	belongs to the Fur family
AOC03_07940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AOC03_07945	COG1253	flavin adenine dinucleotide binding
AOC03_07955	COG0628	permease
AOC03_07960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOC03_07965	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AOC03_07970	COG1671	Belongs to the UPF0178 family
AOC03_07980	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AOC03_08010	COG0793	Belongs to the peptidase S41A family
AOC03_08035	COG1187	pseudouridine synthase activity
AOC03_08060	COG3161	chorismate lyase activity
AOC03_08065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOC03_08070	COG0786	glutamate:sodium symporter activity
AOC03_08075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AOC03_08090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOC03_08095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOC03_08100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOC03_08125	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOC03_08145	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AOC03_08150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOC03_08155	COG0765	amino acid transport
AOC03_08160	COG0765	amino acid transport
AOC03_08165	COG1126	abc transporter atp-binding protein
AOC03_08170	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOC03_08175	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AOC03_08185	COG0730	response to heat
AOC03_08190	COG1196	nuclear chromosome segregation
AOC03_08195	COG3115	cell septum assembly
AOC03_08200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOC03_08230	COG1522	sequence-specific DNA binding
AOC03_08235	COG2962	Rard protein
AOC03_08240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AOC03_08245	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AOC03_08250	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AOC03_08255	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AOC03_08255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOC03_08270	COG0481	GTPase activity
AOC03_08275	COG0681	Belongs to the peptidase S26 family
AOC03_08285	COG0571	ribonuclease III activity
AOC03_08290	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AOC03_08300	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AOC03_08310	COG2885	chlorophyll binding
AOC03_08310	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AOC03_08320	COG1970	mechanosensitive ion channel activity
AOC03_08330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AOC03_08335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOC03_08340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOC03_08360	COG1024	Enoyl-CoA hydratase
AOC03_08365	COG2814	Major facilitator Superfamily
AOC03_08370	COG0643	Histidine kinase
AOC03_08370	COG2198	Histidine kinase
AOC03_08375	COG2201	protein-glutamate methylesterase activity
AOC03_08390	COG0052	Belongs to the universal ribosomal protein uS2 family
AOC03_08395	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AOC03_08400	COG1196	nuclear chromosome segregation
AOC03_08400	COG0741	lytic transglycosylase activity
AOC03_08400	COG0739	heme binding
AOC03_08415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOC03_08425	COG0667	Aldo Keto reductase
AOC03_08430	COG1047	Peptidyl-prolyl cis-trans
AOC03_08435	COG1278	Cold shock
AOC03_08445	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOC03_08455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOC03_08460	COG3153	acetyltransferase
AOC03_08460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOC03_08470	COG0277	FAD linked oxidase domain protein
AOC03_08475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOC03_08480	COG2351	hydroxyisourate hydrolase activity
AOC03_08495	COG2813	Specifically methylates the guanine in position
AOC03_08495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOC03_08500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOC03_08505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOC03_08515	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_08525	COG1764	response to oxidative stress
AOC03_08535	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AOC03_08575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AOC03_08580	COG0456	acetyltransferase
AOC03_08585	COG0789	Transcriptional regulator
AOC03_08590	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AOC03_08595	COG0492	ferredoxin-NADP+ reductase activity
AOC03_08600	COG1674	ftsk spoiiie
AOC03_08610	COG3384	dioxygenase
AOC03_08615	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AOC03_08650	COG0436	Aminotransferase
AOC03_08660	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AOC03_08665	COG0024	Methionine aminopeptidase
AOC03_08695	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AOC03_08700	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AOC03_08705	COG1115	amino acid carrier protein
AOC03_08745	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AOC03_08810	COG0582	viral genome integration into host DNA
AOC03_08820	COG3245	cytochrome
AOC03_08825	COG1131	(ABC) transporter
AOC03_08830	COG0842	Transport permease protein
AOC03_08835	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AOC03_08835	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AOC03_08845	COG0442	prolyl-tRNA aminoacylation
AOC03_08870	COG4682	membrane
AOC03_08875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOC03_08875	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AOC03_08885	COG2350	Protein conserved in bacteria
AOC03_08890	COG2917	probably involved in intracellular septation
AOC03_08895	COG0613	PHP domain protein
AOC03_08905	COG0585	pseudouridine synthase activity
AOC03_08935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOC03_08940	COG2814	Major facilitator Superfamily
AOC03_08945	COG0629	single-stranded DNA binding
AOC03_08950	COG2916	Histone family protein nucleoid-structuring protein H-NS
AOC03_08980	COG0084	hydrolase, TatD family'
AOC03_08985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AOC03_08990	COG0784	Response regulator, receiver
AOC03_08990	COG5002	protein histidine kinase activity
AOC03_08995	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AOC03_09010	COG3706	GGDEF domain
AOC03_09020	COG0714	Associated with various cellular activities
AOC03_09055	COG3135	benzoate transporter
AOC03_09095	COG1953	Uracil, thiamine, allantoin
AOC03_09115	COG0730	response to heat
AOC03_09120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOC03_09125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AOC03_09150	COG0671	phosphoesterase, PA-phosphatase related
AOC03_09170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AOC03_09175	COG3781	membrane
AOC03_09190	COG0745	RESPONSE REGULATOR receiver
AOC03_09195	COG0642	Histidine kinase
AOC03_09200	COG0753	catalase activity
AOC03_09205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOC03_09210	COG0569	domain protein
AOC03_09220	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AOC03_09235	COG0583	DNA-binding transcription factor activity
AOC03_09240	COG1741	Belongs to the pirin family
AOC03_09245	COG0435	Glutathione S-transferase
AOC03_09275	COG2226	methyltransferase
AOC03_09285	COG4589	Belongs to the CDS family
AOC03_09290	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_09300	COG2267	carboxylic ester hydrolase activity
AOC03_09305	COG0303	'Molybdopterin
AOC03_09310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOC03_09315	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOC03_09320	COG0746	molybdenum cofactor guanylyltransferase activity
AOC03_09325	COG0315	cyclic pyranopterin monophosphate synthase activity
AOC03_09335	COG0314	molybdopterin synthase activity
AOC03_09355	COG1971	Probably functions as a manganese efflux pump
AOC03_09370	COG1942	4-Oxalocrotonate Tautomerase
AOC03_09395	COG0840	transmembrane signaling receptor activity
AOC03_09410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOC03_09415	COG0765	amino acid transport
AOC03_09420	COG1126	abc transporter atp-binding protein
AOC03_09425	COG3257	ureidoglycine aminohydrolase activity
AOC03_09430	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AOC03_09440	COG1953	Uracil, thiamine, allantoin
AOC03_09450	COG2351	hydroxyisourate hydrolase activity
AOC03_09475	COG4604	ABC transporter, ATP-binding protein
AOC03_09480	COG4605	iron ion homeostasis
AOC03_09485	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOC03_09490	COG4607	ABC-type enterochelin transport system periplasmic component
AOC03_09525	COG2032	superoxide dismutase activity
AOC03_09545	COG2056	Na+-H+ antiporter family
AOC03_09555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOC03_09570	COG3713	MltA-interacting MipA family protein
AOC03_09575	COG0705	Rhomboid family
AOC03_09575	COG0457	Tetratricopeptide repeat
AOC03_09590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOC03_09635	COG0504	CTP synthase activity
AOC03_09640	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AOC03_09655	COG2217	Heavy metal translocating P-type atpase
AOC03_09660	COG0148	phosphopyruvate hydratase activity
AOC03_09665	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AOC03_09670	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AOC03_09685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOC03_09695	COG0137	argininosuccinate synthase activity
AOC03_09725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AOC03_09730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AOC03_09735	COG0628	permease
AOC03_09750	COG0783	Belongs to the Dps family
AOC03_09760	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AOC03_09765	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AOC03_09775	COG2353	YceI-like domain
AOC03_09795	COG1012	belongs to the aldehyde dehydrogenase family
AOC03_09800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOC03_10055	COG4695	Portal protein
AOC03_10080	COG2268	Band 7 protein
AOC03_10085	COG1585	Membrane protein implicated in regulation of membrane protease activity
AOC03_10100	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_10120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOC03_10130	COG1607	acyl-coa hydrolase
AOC03_10150	COG0556	nucleotide-excision repair
AOC03_10185	COG2860	membrane
AOC03_10195	COG0602	queuosine metabolic process
AOC03_10200	COG2171	N-acyltransferase activity
AOC03_10210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOC03_10215	COG1049	propionate catabolic process, 2-methylcitrate cycle
AOC03_10220	COG3152	Membrane
AOC03_10230	COG1024	Enoyl-CoA hydratase
AOC03_10235	COG0596	Alpha beta hydrolase
AOC03_10245	COG1358	cellular component organization or biogenesis
AOC03_10260	COG0251	oxidation-reduction process
AOC03_10280	COG3275	phosphorelay sensor kinase activity
AOC03_10285	COG3279	Response regulator of the LytR AlgR family
AOC03_10290	COG1288	antiporter activity
AOC03_10320	COG0116	Belongs to the methyltransferase superfamily
AOC03_10320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AOC03_10325	COG0668	transmembrane transport
AOC03_10335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOC03_10345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AOC03_10350	COG0037	tRNA processing
AOC03_10360	COG0348	domain, Protein
AOC03_10365	COG2010	Cytochrome c
AOC03_10380	COG3278	Belongs to the heme-copper respiratory oxidase family
AOC03_10395	COG4591	ABC-type transport system involved in lipoprotein release permease component
AOC03_10400	COG1136	(ABC) transporter
AOC03_10410	COG0658	competence protein
AOC03_10410	COG2333	competence protein COMEC
AOC03_10415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOC03_10415	COG0616	signal peptide processing
AOC03_10430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOC03_10435	COG0477	Major facilitator Superfamily
AOC03_10440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOC03_10450	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AOC03_10455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOC03_10460	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AOC03_10470	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOC03_10470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOC03_10475	COG0778	Nitroreductase
AOC03_10480	COG0509	glycine decarboxylation via glycine cleavage system
AOC03_10490	COG3100	YcgL domain-containing protein
AOC03_10510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOC03_10525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOC03_10535	COG1519	Transferase
AOC03_10540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOC03_10550	COG1178	ABC-type Fe3 transport system permease component
AOC03_10555	COG3842	ATPase activity
AOC03_10560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOC03_10580	COG2962	Rard protein
AOC03_10595	COG1234	tRNA 3'-trailer cleavage
AOC03_10605	COG2815	serine threonine protein kinase
AOC03_10605	COG0515	serine threonine protein kinase
AOC03_10630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOC03_10635	COG0528	UMP kinase activity
AOC03_10640	COG0233	cytoplasmic translational termination
AOC03_10645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOC03_10650	COG0575	Belongs to the CDS family
AOC03_10655	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AOC03_10670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOC03_10675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AOC03_10680	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOC03_10685	COG0733	neurotransmitter:sodium symporter activity
AOC03_10690	COG0343	queuine tRNA-ribosyltransferase activity
AOC03_10710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOC03_10715	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AOC03_10720	COG3178	'Phosphotransferase
AOC03_10725	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOC03_10730	COG1294	oxidase, subunit
AOC03_10735	COG1271	oxidase subunit
AOC03_10750	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AOC03_10765	COG2911	Protein conserved in bacteria
AOC03_10775	COG3040	lipid binding
AOC03_10785	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AOC03_10790	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AOC03_10795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AOC03_10800	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AOC03_10810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOC03_10815	COG0542	response to heat
AOC03_10825	COG0590	tRNA wobble adenosine to inosine editing
AOC03_10840	COG0776	regulation of translation
AOC03_10850	COG0284	orotidine-5'-phosphate decarboxylase activity
AOC03_10865	COG0268	Binds directly to 16S ribosomal RNA
AOC03_10870	COG0702	epimerase
AOC03_10875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOC03_10880	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOC03_10910	COG0316	Belongs to the HesB IscA family
AOC03_10915	COG0822	iron-sulfur transferase activity
AOC03_10940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOC03_10945	COG0138	bifunctional purine biosynthesis protein purh
AOC03_10960	COG2264	protein methyltransferase activity
AOC03_10970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOC03_10985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOC03_10990	COG3139	Protein of unknown function (DUF1315)
AOC03_11000	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AOC03_11005	COG0527	aspartate kinase activity
AOC03_11010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOC03_11035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AOC03_11045	COG3293	Transposase
AOC03_11080	COG0359	binds to the 23S rRNA
AOC03_11085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AOC03_11090	COG0360	Binds together with S18 to 16S ribosomal RNA
AOC03_11105	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AOC03_11110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOC03_11125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOC03_11135	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOC03_11190	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOC03_11195	COG3047	cAMP biosynthetic process
AOC03_11205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOC03_11220	COG1067	ATP-dependent peptidase activity
AOC03_11225	COG0357	Ribosomal RNA small subunit methyltransferase G
AOC03_11230	COG1192	Involved in chromosome partitioning
AOC03_11235	COG1475	DNA binding
AOC03_11240	COG1132	(ABC) transporter
AOC03_11245	COG1663	tetraacyldisaccharide 4'-kinase activity
AOC03_11250	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AOC03_11270	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_11290	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AOC03_11295	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AOC03_11310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOC03_11320	COG3263	regulation of cellular component size
AOC03_11325	COG0583	DNA-binding transcription factor activity
AOC03_11330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOC03_11335	COG5383	Protein conserved in bacteria
AOC03_11340	COG1012	belongs to the aldehyde dehydrogenase family
AOC03_11350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOC03_11355	COG0277	FAD linked oxidase domain protein
AOC03_11360	COG1929	Belongs to the glycerate kinase type-1 family
AOC03_11365	COG1448	Aminotransferase
AOC03_11445	COG1401	restriction endodeoxyribonuclease activity
AOC03_11455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOC03_11460	COG1061	Type III restriction enzyme res subunit
AOC03_11490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOC03_11565	COG2267	carboxylic ester hydrolase activity
AOC03_11570	COG2146	nitrite reductase [NAD(P)H] activity
AOC03_11585	COG3971	2-oxopent-4-enoate hydratase activity
AOC03_11600	COG2070	2-Nitropropane dioxygenase
AOC03_11610	COG4638	Rieske (2fe-2S)
AOC03_11625	COG2814	Major facilitator Superfamily
AOC03_11645	COG0583	DNA-binding transcription factor activity
AOC03_11650	COG2259	Doxx family
AOC03_11655	COG0431	NADPH-dependent FMN reductase
AOC03_11670	COG1741	Belongs to the pirin family
AOC03_11690	COG1301	dicarboxylic acid transport
AOC03_11695	COG0583	DNA-binding transcription factor activity
AOC03_11700	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOC03_11705	COG5383	Protein conserved in bacteria
AOC03_11710	COG0277	FAD linked oxidase domain protein
AOC03_11725	COG0300	oxidoreductase activity
AOC03_11730	COG0617	tRNA 3'-terminal CCA addition
AOC03_11760	COG2096	Adenosyltransferase
AOC03_11765	COG0215	cysteine-tRNA ligase activity
AOC03_11775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOC03_11780	COG0259	pyridoxamine-phosphate oxidase activity
AOC03_11805	COG2130	NADP-dependent
AOC03_11810	COG1979	alcohol dehydrogenase
AOC03_11815	COG1309	transcriptional regulator
AOC03_11830	COG0415	Belongs to the DNA photolyase family
AOC03_11875	COG0318	PFAM AMP-dependent synthetase and ligase
AOC03_11880	COG1024	Enoyl-CoA hydratase
AOC03_12150	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
AOC03_12165	COG0024	Methionine aminopeptidase
AOC03_12175	COG1959	2 iron, 2 sulfur cluster binding
AOC03_12180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOC03_12215	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AOC03_12245	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AOC03_12270	COG0732	type I restriction modification DNA specificity domain
AOC03_12285	COG1192	Involved in chromosome partitioning
AOC03_12295	COG1802	Transcriptional regulator
AOC03_12305	COG4948	Mandelate Racemase Muconate Lactonizing
AOC03_12345	COG1028	Short-chain dehydrogenase reductase Sdr
AOC03_12355	COG1959	2 iron, 2 sulfur cluster binding
AOC03_12360	COG2910	NAD(P)H-binding
AOC03_12365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOC03_12375	COG1136	(ABC) transporter
AOC03_12390	COG1309	transcriptional regulator
AOC03_12405	COG1136	(ABC) transporter