locus-tag	class	description
E9099_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E9099_00015	ENOG4105QD8	tetrapyrrole corrin porphyrin
E9099_00030	ENOG4105HHA	aminodeoxychorismate lyase
E9099_00040	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E9099_00045	ENOG4105C0H	protease
E9099_00060	ENOG4105KD7	acetyltransferase
E9099_00070	ENOG41080HT	Transcriptional regulator, arsr family
E9099_00100	ENOG4105CGD	Nad-dependent epimerase dehydratase
E9099_00115	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
E9099_00120	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E9099_00135	ENOG4105EUJ	GTP cyclohydrolase i
E9099_00145	ENOG4105CHR	reductase
E9099_00150	ENOG4108V06	Glutathione peroxidase
E9099_00165	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E9099_00295	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E9099_00315	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E9099_00320	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E9099_00325	ENOG4105K70	DNA-binding protein
E9099_00330	ENOG4108UJU	UPF0301 protein
E9099_00335	ENOG4105F0I	Aminotransferase
E9099_00350	ENOG4105CUT	histidyl-tRNA synthetase
E9099_00365	ENOG4108KPZ	tonB-dependent Receptor
E9099_00370	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
E9099_00375	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E9099_00380	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
E9099_00385	ENOG4108NEV	two component transcriptional regulator, LytTR family
E9099_00390	ENOG4105C25	Primosomal protein n'
E9099_00405	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E9099_00410	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E9099_00425	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E9099_00460	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E9099_00475	ENOG4105C5H	ABC transporter
E9099_00490	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
E9099_00495	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E9099_00510	ENOG4105E9K	Isocitrate dehydrogenase
E9099_00525	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
E9099_00590	ENOG4105C22	threonyL-tRNA synthetase
E9099_00595	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
E9099_00600	ENOG4105VJV	50s ribosomal protein L35
E9099_00605	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E9099_00610	ENOG4108HCJ	Hydrolase
E9099_00615	ENOG4108Q35	Adenylate
E9099_00630	ENOG4105DSF	transport protein
E9099_00635	ENOG4105CDU	Replicative dna helicase
E9099_00640	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
E9099_00655	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E9099_00660	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E9099_00665	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E9099_00680	ENOG4105VEJ	Heat shock protein
E9099_00685	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
E9099_00690	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E9099_00715	ENOG4105EWK	phytoene
E9099_00735	ENOG4105CUG	Oligopeptidase b
E9099_00740	ENOG4107QX9	Thiol disulfide interChange protein
E9099_00750	ENOG4108I0Z	Aconitate hydratase
E9099_00755	ENOG4107QIJ	Aconitate hydratase 2
E9099_00760	ENOG4105EXC	Acyl-transferase
E9099_00770	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E9099_00775	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E9099_00785	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E9099_00820	ENOG4105CHR	reductase
E9099_00975	ENOG4105KPY	Small multidrug resistance protein
E9099_01005	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E9099_01060	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E9099_01065	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
E9099_01110	ENOG4105VIE	preprotein translocase, subunit YajC
E9099_01120	ENOG4107R6T	Involved in the transcription termination process (By similarity)
E9099_01130	ENOG4105BZ1	(ABC) transporter
E9099_01145	ENOG4108Z7R	Chaperone CsaA
E9099_01155	ENOG4108YYS	metal-dependent hydrolase (By similarity)
E9099_01160	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
E9099_01170	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E9099_01175	ENOG4105C2X	Arabinose 5-phosphate isomerase
E9099_01180	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
E9099_01190	ENOG4108IUZ	ABC transporter
E9099_01195	ENOG4105EE5	Membrane protein terC
E9099_01220	ENOG4107T8Q	Glycosyl transferase (Group 1
E9099_01240	ENOG4108RYC	glycosyltransferase
E9099_01245	ENOG4108RJ9	Glycosyl transferase, family 2
E9099_01255	ENOG4105D7W	serine acetyltransferase
E9099_01275	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
E9099_01280	ENOG4105D2T	synthase
E9099_01310	ENOG4105K64	Glycosyl transferase, family 2
E9099_01320	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
E9099_01325	ENOG4105K64	Glycosyl transferase, family 2
E9099_01330	ENOG4108YRB	methyltransferase
E9099_01335	ENOG4105K64	Glycosyl transferase, family 2
E9099_01345	ENOG4105K64	Glycosyl transferase, family 2
E9099_01355	ENOG4105EY8	ABC transporter
E9099_01360	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
E9099_01370	ENOG4107YJ4	chain length determinant protein
E9099_01380	ENOG4105C5H	ABC transporter
E9099_01405	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E9099_01420	ENOG4107QP3	malate synthase g
E9099_01425	ENOG4107RET	Isocitrate lyase
E9099_01430	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E9099_01435	ENOG4105C5R	Aminotransferase
E9099_01540	ENOG4105EMN	RNA polymerase sigma factor
E9099_01550	ENOG4105DJT	lAO AO transport system ATPase
E9099_01610	ENOG4107QI1	Mate efflux family protein
E9099_01620	ENOG4105EA8	2-Nitropropane dioxygenase
E9099_01630	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E9099_01645	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E9099_01650	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E9099_01665	ENOG4105VRT	cytoplasmic protein
E9099_01680	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E9099_01690	ENOG4105DY8	decarboxylase
E9099_01695	ENOG41074B2	UPF0747 protein
E9099_01715	ENOG4107RBI	VanW family
E9099_01720	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
E9099_01725	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E9099_01730	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E9099_01740	ENOG41083ND	50S ribosomal protein L33
E9099_01745	ENOG4105KDC	50s ribosomal protein l28
E9099_01750	ENOG4105CEV	competence damage-inducible protein
E9099_01760	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
E9099_01790	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E9099_01795	ENOG4107RJ1	sodium solute
E9099_01810	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E9099_01815	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E9099_01825	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
E9099_01890	ENOG4105E18	UPF0276 protein
E9099_01965	ENOG4107R3N	Filamentation induced by cAMP protein fic
E9099_02005	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
E9099_02035	ENOG4108RPX	mosc domain containing protein
E9099_02050	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
E9099_02065	ENOG4105C1J	atp-dependent rna helicase
E9099_02085	ENOG41090R7	Ferric uptake
E9099_02090	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E9099_02100	ENOG4105C8Y	Acetylornithine aminotransferase
E9099_02120	ENOG4105E2X	shikimate dehydrogenase
E9099_02135	ENOG4105DXN	mazG family
E9099_02145	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E9099_02150	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E9099_02155	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
E9099_02170	ENOG4105CKK	Glycosyl transferase, family 2
E9099_02175	ENOG4106WTF	Glycosyl transferase, family 2
E9099_02190	ENOG4106WTF	Glycosyl transferase, family 2
E9099_02195	ENOG4108TJN	glycosyl transferase group 1
E9099_02220	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E9099_02225	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
E9099_02235	ENOG4107SF2	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
E9099_02250	ENOG4105CJ1	ABC, transporter
E9099_02275	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E9099_02290	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
E9099_02295	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E9099_02300	ENOG4105BZU	Histidine kinase
E9099_02305	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E9099_02330	ENOG4105CSR	polyphosphate kinase 2
E9099_02340	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E9099_02350	ENOG4105EGS	Mechanosensitive ion channel
E9099_02355	ENOG4105RHA	ABC transporter, permease
E9099_02360	ENOG4108IUX	(ABC) transporter
E9099_02365	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E9099_02370	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E9099_02375	ENOG4108YYC	ycei family
E9099_02380	ENOG4105KVH	Transcriptional regulator
E9099_02405	ENOG4105F6J	Alpha beta hydrolase fold
E9099_02455	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E9099_02465	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E9099_02470	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E9099_02475	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E9099_02480	ENOG4107VNI	ribosomal protein l10
E9099_02485	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E9099_02490	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E9099_02495	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E9099_02510	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E9099_02535	ENOG4105MS2	ribosomal subunit Interface protein
E9099_02540	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E9099_02545	ENOG41083X6	30S ribosomal protein S21
E9099_02550	ENOG4105E5K	Alpha-amylase
E9099_02560	ENOG4105C1G	acyl-Coa dehydrogenase
E9099_02570	ENOG4105BZG	amino acid carrier protein
E9099_02575	ENOG4107SVH	Potassium channel protein
E9099_02670	ENOG4105BZU	Histidine kinase
E9099_02715	ENOG4105DFU	Cell wall formation (By similarity)
E9099_02725	ENOG4105C27	TonB-dependent Receptor Plug
E9099_02730	ENOG4105DY9	regulatoR
E9099_02735	ENOG4108HRK	Histidine kinase
E9099_02765	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E9099_02770	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E9099_02775	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E9099_02780	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E9099_02785	ENOG4105DGW	oligopeptidase A
E9099_02825	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E9099_02830	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E9099_02840	ENOG4107QJZ	Glycosyl transferase, family 2
E9099_02895	ENOG4108JJA	ABC, transporter
E9099_02910	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E9099_02925	ENOG4105CHM	Aminotransferase
E9099_02930	ENOG4107R0I	Cell wall formation (By similarity)
E9099_02935	ENOG4105K6V	RNA polymerase
E9099_02945	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
E9099_02965	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E9099_02980	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E9099_02985	ENOG4105EGD	dinuclear metal center protein, YbgI family
E9099_02995	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E9099_03010	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
E9099_03015	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
E9099_03035	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
E9099_03040	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
E9099_03065	ENOG4105H3G	oxidoreductase
E9099_03095	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E9099_03125	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E9099_03160	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E9099_03175	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
E9099_03210	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E9099_03220	ENOG4105BZU	Histidine kinase
E9099_03225	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E9099_03270	ENOG4105CGK	Exodeoxyribonuclease III
E9099_03275	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
E9099_03285	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E9099_03300	ENOG4108RMU	ferritin dps family protein
E9099_03335	ENOG4107PU6	Membrane
E9099_03450	ENOG4105C5H	ABC transporter
E9099_03460	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
E9099_03480	ENOG4105E6M	Sulphatase-modifying factor protein
E9099_03490	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E9099_03495	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E9099_03500	ENOG4108JUA	Transcriptional regulator
E9099_03520	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E9099_03525	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E9099_03545	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E9099_03550	ENOG4105DFF	Rod shape-determining protein mreb
E9099_03565	ENOG4107RVG	penicillin-binding protein
E9099_03570	ENOG4105CNI	cell division protein FtsW
E9099_03590	ENOG4105ZMH	deoxynucleoside kinase
E9099_03600	ENOG4105F0N	pyrophosphate phospho-hydrolase
E9099_03615	ENOG4105CPP	Dehydrogenase, E1 component
E9099_03620	ENOG4105TPV	
E9099_03625	ENOG4105C10	Electron transfer flavoprotein
E9099_03635	ENOG4105D9N	nucleoside
E9099_03640	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
E9099_03650	ENOG4105E08	Glycoside hydrolase, family 9
E9099_03670	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
E9099_03680	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E9099_03690	ENOG4105CHR	reductase
E9099_03695	ENOG4105FE9	pseudouridine synthase
E9099_03720	ENOG4105Y7M	Transcriptional regulator, TetR family
E9099_03725	ENOG4105CBX	hi0933 family
E9099_03730	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
E9099_03785	ENOG4105E0R	Deoxyhypusine synthase
E9099_03840	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
E9099_03845	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E9099_03850	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
E9099_03870	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
E9099_03875	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E9099_03885	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
E9099_03890	ENOG4105EVN	Prephenate dehydrogenase
E9099_03900	ENOG4105CQC	Prephenate dehydratase
E9099_03920	ENOG4105C6T	cysteine synthase
E9099_03925	ENOG4105D7W	serine acetyltransferase
E9099_03930	ENOG4105CAY	ferredoxin--nadp reductase
E9099_03935	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E9099_03940	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E9099_03945	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
E9099_03955	ENOG4105C11	sulfate adenylyltransferase), subunit 2
E9099_03960	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
E9099_03970	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
E9099_03975	ENOG4105SYT	Methylenetetrahydrofolate reductase
E9099_03980	ENOG4105C3R	Methionine synthase
E9099_03995	ENOG4105C28	cystathionine
E9099_04000	ENOG4105CFH	Aspartokinase
E9099_04020	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E9099_04025	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E9099_04035	ENOG4105CHM	Aminotransferase
E9099_04050	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E9099_04055	ENOG4105C1A	potassium transporter peripheral membrane
E9099_04060	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E9099_04070	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E9099_04080	ENOG4105D2N	Aldolase
E9099_04085	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E9099_04095	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E9099_04100	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E9099_04110	ENOG4105II7	pyrroline-5-carboxylate reductase
E9099_04115	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
E9099_04120	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E9099_04125	ENOG4107RRZ	synthase
E9099_04150	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
E9099_04170	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E9099_04185	ENOG4105CJW	magnesium transporter
E9099_04195	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
E9099_04205	ENOG4105KTH	gatB Yqey
E9099_04210	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E9099_04215	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E9099_04225	ENOG4105DFU	Cell wall formation (By similarity)
E9099_04230	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E9099_04235	ENOG4105CNI	cell division protein FtsW
E9099_04240	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E9099_04245	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E9099_04250	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E9099_04255	ENOG4105CJN	penicillin-binding protein
E9099_04265	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E9099_04270	ENOG4107YM1	mraZ protein
E9099_04280	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
E9099_04415	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E9099_04435	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E9099_04440	ENOG4105CN1	protease
E9099_04445	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E9099_04455	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E9099_04460	ENOG4108QBX	(LipO)protein
E9099_04465	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
E9099_04475	ENOG4105DUX	Transporter
E9099_04475	ENOG4105DUX	Transporter
E9099_04480	ENOG4105DUX	Transporter
E9099_04505	ENOG4105C37	(CBS) domain
E9099_04530	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
E9099_04540	ENOG4107Y2X	deaminase
E9099_04545	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E9099_04565	ENOG4105EEQ	Na H antiporter
E9099_04590	ENOG4105C27	TonB-dependent Receptor Plug
E9099_04610	ENOG4105C72	UPF0176 protein
E9099_04620	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
E9099_04635	ENOG4105CKK	Glycosyl transferase, family 2
E9099_04640	ENOG41075SV	phosphoribosyltransferase
E9099_04650	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
E9099_04655	ENOG4108UVJ	appr-1-p processing domain protein
E9099_04665	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E9099_04695	ENOG4107SJS	nitrite reductase, (NAD(P)H)
E9099_04715	ENOG4105CND	Glycosyl transferase, family 2
E9099_04725	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E9099_04730	ENOG4108UJD	30S ribosomal protein S9
E9099_04735	ENOG4105CE9	30S ribosomal protein S2
E9099_04740	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
E9099_04745	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E9099_04750	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
E9099_04770	ENOG4105C5S	asparaginyl-tRNA synthetase
E9099_04775	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E9099_04815	ENOG4105HDK	L-asparaginase
E9099_04820	ENOG4105F8V	Hydrolase, tatD family
E9099_04855	ENOG4105WH1	Two component transcriptional regulator luxr family
E9099_04860	ENOG4105C7S	Dehydrogenase
E9099_04870	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E9099_04935	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
E9099_04940	ENOG4105UFH	BadM Rrf2 family transcriptional regulator
E9099_04970	ENOG4105BZS	acriflavin resistance protein
E9099_04975	ENOG4105C9M	aspartyl-trna synthetase
E9099_04990	ENOG4108Z6B	deaminase
E9099_05015	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E9099_05025	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
E9099_05035	ENOG4105C27	TonB-dependent Receptor Plug
E9099_05065	ENOG4105ER2	Ompa motb domain protein
E9099_05085	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E9099_05090	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E9099_05100	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
E9099_05115	ENOG4105CN1	protease
E9099_05130	ENOG4105DG6	mannose-6-phosphate isomerase
E9099_05145	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E9099_05150	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E9099_05155	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
E9099_05170	ENOG4105DTN	riboflavin biosynthesis protein ribF
E9099_05180	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E9099_05200	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E9099_05205	ENOG4105CJW	magnesium transporter
E9099_05215	ENOG4108JQ1	Dehydrogenase
E9099_05245	ENOG4105CFH	Aspartokinase
E9099_05255	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E9099_05275	ENOG4105BZU	Histidine kinase
E9099_05285	ENOG4108JA2	transcriptioN-repair coupling factor
E9099_05305	ENOG4105C8T	Leucyl-tRNA synthetase
E9099_05310	ENOG4107RJ9	Cell division protein FtsX
E9099_05320	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E9099_05325	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E9099_05340	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E9099_05345	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E9099_05355	ENOG4107XWI	flavin reductase domain protein, FMN-binding
E9099_05360	ENOG4105BZU	Histidine kinase
E9099_05375	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E9099_05390	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
E9099_05405	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
E9099_05415	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
E9099_05425	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
E9099_05440	ENOG4105K46	50S ribosomal protein l27
E9099_05445	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E9099_05470	ENOG4105C59	p-type ATPase
E9099_05475	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E9099_05545	ENOG4105BZU	Histidine kinase
E9099_05560	ENOG4105C37	(CBS) domain
E9099_05565	ENOG4108UUM	single-stranded DNA-binding protein
E9099_05575	ENOG4105K70	DNA-binding protein
E9099_05580	ENOG4105C03	ribonuclease
E9099_05585	ENOG4105UYK	outer membrane protein a
E9099_05600	ENOG4105CPC	Aldo Keto reductase
E9099_05605	ENOG4105ER2	Ompa motb domain protein
E9099_05610	ENOG4105CGK	Exodeoxyribonuclease III
E9099_05635	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
E9099_05655	ENOG4105MJ2	Competence protein
E9099_05665	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
E9099_05675	ENOG4105DY9	regulatoR
E9099_05680	ENOG4108HRK	Histidine kinase
E9099_05695	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E9099_05710	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
E9099_05730	ENOG4105E33	succinate dehydrogenase
E9099_05755	ENOG4107RAQ	aminopeptidase
E9099_05775	ENOG4105CYC	Transferase
E9099_05945	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E9099_05980	ENOG4105CFH	Aspartokinase
E9099_06015	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E9099_06020	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E9099_06050	ENOG4105C9B	Cysteine desulfurase
E9099_06060	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
E9099_06065	ENOG4105VG1	fes assembly suf system protein
E9099_06085	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E9099_06135	ENOG4105BZU	Histidine kinase
E9099_06185	ENOG4108UUM	single-stranded DNA-binding protein
E9099_06210	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E9099_06225	ENOG4105RWF	major outer membrane protein OmpA
E9099_06255	ENOG4105C9K	Endothelin-converting enzyme 1
E9099_06275	ENOG4105EXW	epimerase dehydratase
E9099_06285	ENOG4105DZP	Membrane-associated zinc metalloprotease
E9099_06290	ENOG4108KF3	Electron transport protein SCO1 SenC
E9099_06300	ENOG4105CE1	Ferrous iron transport protein b
E9099_06320	ENOG4105D05	Receptor
E9099_06330	ENOG4105DSE	periplasmic solute binding protein
E9099_06335	ENOG4105DIK	(ABC) transporter
E9099_06340	ENOG4107RPQ	ABC transporter
E9099_06345	ENOG4107RBD	ABC, transporter
E9099_06350	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E9099_06355	ENOG4108Y6J	UPF0403 protein
E9099_06390	ENOG4105W4W	Transcriptional regulator
E9099_06410	ENOG4105E39	Enoyl-CoA hydratase
E9099_06415	ENOG4108HWS	Histidine kinase
E9099_06430	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
E9099_06445	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E9099_06455	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
E9099_06470	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E9099_06480	ENOG4105K5B	UPF0225 protein
E9099_06485	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E9099_06490	ENOG4105D52	delta-aminolevulinic acid dehydratase
E9099_06510	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E9099_06540	ENOG4108JQ6	ABC transporter
E9099_06555	ENOG4107QP7	CoA-transferase subunit A
E9099_06560	ENOG4108JQC	penicillin-binding protein 1A
E9099_06565	ENOG410647Z	gliding motility-associated lipoprotein GldH
E9099_06570	ENOG4105MA4	psp1 domain protein
E9099_06580	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E9099_06610	ENOG4105C31	Tryptophanyl-tRNA synthetase
E9099_06625	ENOG4105NAU	thioesterase Superfamily protein
E9099_06630	ENOG4105DR5	peptidase
E9099_06645	ENOG4108J3C	UTP-glucose-1-phosphate uridylyltransferase
E9099_06655	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E9099_06670	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
E9099_06675	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
E9099_06680	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E9099_06685	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
E9099_06695	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
E9099_06745	ENOG4105DKP	glycosyl transferase, family 9
E9099_06755	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
E9099_06770	ENOG4105C12	Phosphoribosylglycinamide synthetase
E9099_06810	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E9099_06820	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E9099_06825	ENOG4105D3Q	Sugar transferase
E9099_06830	ENOG4108DRC	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E9099_06835	ENOG4105D3Q	Sugar transferase
E9099_06875	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
E9099_06905	ENOG4107R5Z	Oxidoreductase domain protein
E9099_06910	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E9099_06915	ENOG4105J5G	Transferase hexapeptide repeat containing protein
E9099_06920	ENOG4108IAJ	Nad-dependent epimerase dehydratase
E9099_06925	ENOG4107QQG	Dehydrogenase
E9099_06935	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E9099_06945	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E9099_06970	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E9099_06980	ENOG4107X35	defense response to bacterium
E9099_06985	ENOG4105BZA	Phosphoglycerate kinase
E9099_07000	ENOG4105CBD	Diacylglycerol kinase
E9099_07020	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
E9099_07025	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E9099_07040	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E9099_07085	ENOG4105CX6	glutaminyL-tRNA synthetase
E9099_07120	ENOG4105K8R	UPF0145 protein
E9099_07125	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E9099_07130	ENOG4108YZG	isomerase
E9099_07135	ENOG4105PGM	cation diffusion facilitator family transporter
E9099_07140	ENOG4107YB6	acetyltransferase, (GNAT) family
E9099_07150	ENOG4105CN1	protease
E9099_07155	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E9099_07175	ENOG4105C8F	Beta-lactamase domain protein
E9099_07180	ENOG4105CHH	sulfate transporter
E9099_07190	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E9099_07215	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E9099_07250	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E9099_07265	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E9099_07270	ENOG4108ZVT	methylmalonyl-coA epimerase
E9099_07285	ENOG4105C01	Dihydroxy-acid dehydratase
E9099_07290	ENOG4105C7K	acetolactate synthase
E9099_07295	ENOG4108ZP8	Acetolactate synthase small subunit
E9099_07300	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E9099_07305	ENOG4105C7B	Threonine dehydratase
E9099_07310	ENOG4105C26	Dehydrogenase
E9099_07320	ENOG4105CDH	Citrulline--aspartate ligase
E9099_07325	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E9099_07335	ENOG4105C8Y	Acetylornithine aminotransferase
E9099_07340	ENOG4107REN	Carbamoyltransferase
E9099_07345	ENOG4107T6X	nag kinase
E9099_07355	ENOG4105CH7	arginosuccinase
E9099_07375	ENOG4108YZA	Nitrogen regulatory protein pii
E9099_07385	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E9099_07390	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E9099_07395	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E9099_07400	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E9099_07415	ENOG4108R6K	riboflavin synthase, subunit alpha
E9099_07420	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E9099_07430	ENOG4105WXV	50S ribosomal protein L32
E9099_07435	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E9099_07440	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E9099_07445	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E9099_07470	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
E9099_07485	ENOG410756H	nucleotidyltransferase
E9099_07490	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
E9099_07515	ENOG4108S2Y	peptide Chain Release factor
E9099_07530	ENOG4105E0Y	RtcB Protein
E9099_07575	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E9099_07595	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E9099_07600	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E9099_07605	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E9099_07610	ENOG4107T8J	thymidine kinase
E9099_07635	ENOG4108RG0	uracil-dna glycosylase
E9099_07650	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E9099_07665	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
E9099_07670	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
E9099_07680	ENOG4107QI1	Mate efflux family protein
E9099_07720	ENOG4105C4R	Atp-dependent dna helicase
E9099_07730	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E9099_07735	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
E9099_07745	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E9099_07750	ENOG4105DWF	phosphomethylpyrimidine kinase
E9099_07755	ENOG4108B1Q	Ribonuclease
E9099_07760	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E9099_07765	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E9099_07770	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E9099_07775	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E9099_07785	ENOG4105CA9	Pyruvate kinase
E9099_07800	ENOG41080ZE	Adenylate cyclase
E9099_07805	ENOG4108JQB	penicillin-binding protein 1C
E9099_07815	ENOG4105C26	Dehydrogenase
E9099_07840	ENOG4105EMU	Dehydrogenase
E9099_07845	ENOG4107QM2	Aldo Keto reductase
E9099_07850	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E9099_07865	ENOG4107QVM	von Willebrand factor, type A
E9099_07870	ENOG4107QVM	von Willebrand factor, type A
E9099_07915	ENOG4105CHH	sulfate transporter
E9099_07920	ENOG41077A9	carbonic anhydrase
E9099_07935	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E9099_07945	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E9099_07970	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E9099_07990	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
E9099_08020	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
E9099_08030	ENOG4109066	lysm domain bon superfamily protein
E9099_08035	ENOG4105KVH	Transcriptional regulator
E9099_08130	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
E9099_08135	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E9099_08140	ENOG4105DSJ	YicC domain protein
E9099_08175	ENOG4105C28	cystathionine
E9099_08185	ENOG4105D82	Glutamate dehydrogenase
E9099_08195	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
E9099_08200	ENOG4107ENK	receptor
E9099_08225	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E9099_08245	ENOG4105VMP	Transcriptional regulator
E9099_08270	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E9099_08285	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E9099_08295	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E9099_08300	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
E9099_08305	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
E9099_08320	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E9099_08330	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E9099_08345	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E9099_08350	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E9099_08360	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E9099_08365	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E9099_08370	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
E9099_08375	ENOG4105D78	K07001 NTE family protein
E9099_08380	ENOG4105F1J	Homogentisate 1,2-dioxygenase
E9099_08385	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
E9099_08395	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
E9099_08405	ENOG4107QP8	phosphohexose isomerase
E9099_08410	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E9099_08470	ENOG41063TF	transcriptional regulator (AraC
E9099_08475	ENOG4105DGU	Histone deacetylase
E9099_08495	ENOG4108ZG0	Ompa motb domain protein
E9099_08505	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E9099_08510	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
E9099_08515	ENOG41080R2	UPF0102 protein
E9099_08525	ENOG4108MN8	Membrane
E9099_08560	ENOG4108VVK	transcriptional Regulator, AsnC
E9099_08570	ENOG4105M08	Membrane
E9099_08575	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
E9099_08590	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
E9099_08595	ENOG4105CD3	dihydroorotase
E9099_08610	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E9099_08625	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E9099_08630	ENOG4105BZU	Histidine kinase
E9099_08635	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E9099_08640	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E9099_08660	ENOG41083MR	nifu domain-containing protein
E9099_08665	ENOG4105CAY	ferredoxin--nadp reductase
E9099_08670	ENOG4108ZIT	Ferredoxin, 2FE-2S
E9099_08685	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
E9099_08690	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E9099_08695	ENOG4105K5M	30s ribosomal protein S16
E9099_08710	ENOG4105C0B	DNA polymerase III (alpha subunit)
E9099_08715	ENOG4105K63	Thioredoxin
E9099_08720	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E9099_08795	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
E9099_08800	ENOG4105CSA	Coproporphyrinogen iii oxidase
E9099_08835	ENOG4105BZU	Histidine kinase
E9099_08845	ENOG4105BZU	Histidine kinase
E9099_08855	ENOG4105DY9	regulatoR
E9099_08860	ENOG4105K4I	Scp-like extracellular
E9099_08870	ENOG4105WH1	Two component transcriptional regulator luxr family
E9099_08880	ENOG4107RY6	amino acid
E9099_08930	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E9099_08940	ENOG4105DG6	mannose-6-phosphate isomerase
E9099_08945	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E9099_08965	ENOG4107VAM	peptidase, m28
E9099_08970	ENOG4108UZ3	Transporter
E9099_08985	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E9099_09000	ENOG4105C27	TonB-dependent Receptor Plug
E9099_09015	ENOG4107URF	beta-phospho-glucomutase
E9099_09030	ENOG4105CJQ	hydrolase, family 31
E9099_09035	ENOG4107T9C	Alpha amylase catalytic region
E9099_09045	ENOG4105CCT	upf0313 protein
E9099_09050	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
E9099_09080	ENOG4105NI8	Cytosine-specific methyltransferase
E9099_09085	ENOG4105C2M	dna polymerase I
E9099_09100	ENOG4105K63	Thioredoxin
E9099_09125	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
E9099_09130	ENOG4105CHV	Transcription elongation factor NusA
E9099_09135	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
E9099_09150	ENOG4107SFQ	iron-sulfur binding
E9099_09180	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E9099_09200	ENOG4105C6K	Malic enzyme
E9099_09205	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E9099_09215	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E9099_09240	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
E9099_09245	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
E9099_09265	ENOG4108KF3	Electron transport protein SCO1 SenC
E9099_09270	ENOG4108SJC	Membrane
E9099_09280	ENOG4105C19	ABC transporter
E9099_09285	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E9099_09290	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E9099_09295	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E9099_09305	ENOG41072GX	Peptidase M22 Glycoprotease
E9099_09310	ENOG4105D64	Mechanosensitive ion channel
E9099_09335	ENOG4108HRK	Histidine kinase
E9099_09340	ENOG4108NEV	two component transcriptional regulator, LytTR family
E9099_09345	ENOG4108Z0R	Transferase
E9099_09365	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E9099_09375	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E9099_09385	ENOG4105EV9	Alpha Beta Hydrolase
E9099_09390	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E9099_09400	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E9099_09410	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E9099_09415	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E9099_09430	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E9099_09435	ENOG41083X6	30S ribosomal protein S21
E9099_09440	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E9099_09485	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E9099_09515	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
E9099_09520	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
E9099_09530	ENOG4105EY3	heparinase II III family protein
E9099_09540	ENOG4105C27	TonB-dependent Receptor Plug
E9099_09555	ENOG4105DJB	Major Facilitator Superfamily
E9099_09585	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E9099_09590	ENOG4105CMR	udp-glucose 4-epimerase
E9099_09600	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E9099_09605	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E9099_09610	ENOG4105DZ0	fad dependent oxidoreductase
E9099_09615	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E9099_09620	ENOG4107ZHV	Transcriptional regulator
E9099_09625	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
E9099_09640	ENOG4105C26	Dehydrogenase
E9099_09645	ENOG4105NWN	ApaG protein
E9099_09655	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E9099_09660	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E9099_09665	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E9099_09670	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E9099_09675	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E9099_09695	ENOG4105CJ2	(LipO)protein
E9099_09700	ENOG4105M08	Membrane
E9099_09705	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E9099_09720	ENOG4105CYC	Transferase
E9099_09730	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E9099_09735	ENOG4108K0D	peptidase, M48
E9099_09745	ENOG4105MA6	gCN5-related N-acetyltransferase
E9099_09770	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
E9099_09800	ENOG4105CGP	Urocanate hydratase
E9099_09810	ENOG4105K6H	D-cysteine desulfhydrase
E9099_09820	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
E9099_09840	ENOG4108Z12	YiaAB two helix domain-containing protein
E9099_09855	ENOG4105CRK	lysyL-tRNA synthetase
E9099_09860	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E9099_09875	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E9099_09940	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
E9099_09945	ENOG4105E6M	Sulphatase-modifying factor protein
E9099_09960	ENOG4105KG3	cytidine deaminase
E9099_09970	ENOG4105C7S	Dehydrogenase
E9099_09980	ENOG4105CHR	reductase
E9099_10010	ENOG4105C75	arginyL-tRNA synthetase
E9099_10050	ENOG4105C27	TonB-dependent Receptor Plug
E9099_10080	ENOG4105C26	Dehydrogenase
E9099_10085	ENOG4105CK2	sodium dicarboxylate symporter
E9099_10130	ENOG4105DHJ	ABC, transporter
E9099_10150	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
E9099_10155	ENOG4105KNE	Phosphatidate cytidylyltransferase
E9099_10165	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E9099_10170	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
E9099_10185	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E9099_10190	ENOG41062IR	nudix hydrolase
E9099_10210	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
E9099_10220	ENOG4105CHH	sulfate transporter
E9099_10225	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E9099_10235	ENOG4105CPF	Cell wall formation (By similarity)
E9099_10240	ENOG4105D9P	serine threonine protein kinase
E9099_10245	ENOG4105C34	Pseudouridine synthase
E9099_10250	ENOG4105D1Q	UPF0246 protein
E9099_10305	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E9099_10345	ENOG4108NPY	Ankyrin repeat protein
E9099_10465	ENOG4105WH1	Two component transcriptional regulator luxr family
E9099_10505	ENOG4105NVB	glycoside hydrolase, family 19
E9099_10515	ENOG4105C1J	atp-dependent rna helicase
E9099_10525	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
E9099_10535	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E9099_10555	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E9099_10565	ENOG41082IR	Excinuclease ABC C subunit domain protein
E9099_10570	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E9099_10575	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
E9099_10580	ENOG4105DK0	Indole-3-glycerol phosphate synthase
E9099_10585	ENOG4108I0Q	anthranilate phosphoribosyltransferase
E9099_10590	ENOG4105DDQ	anthranilate synthase
E9099_10595	ENOG4105CRQ	synthase (Component I)
E9099_10600	ENOG41085GJ	domain protein
E9099_10615	ENOG4107YB1	Trehalose corynomycolyl transferase
E9099_10620	ENOG4105CNM	Receptor
E9099_10625	ENOG41075H3	AraC family transcriptional regulator
E9099_10655	ENOG4108UB4	uncharacterized protein ygjQ
E9099_10695	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
E9099_10715	ENOG4105CI3	gtp-binding protein typa
E9099_10735	ENOG4105EGZ	biosynthesis protein
E9099_10745	ENOG4107XU6	Glycosyl transferase (Group 1
E9099_10755	ENOG4105K64	Glycosyl transferase, family 2
E9099_10765	ENOG4105CAK	Cell division ATP-binding protein ftsE
E9099_10780	ENOG4105EFZ	amidohydrolase
E9099_10810	ENOG4105EHZ	conserved protein UCP016719
E9099_10815	ENOG4107R34	abc transporter permease protein
E9099_10825	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E9099_10840	ENOG4105W5Q	DNA repair protein (RadC
E9099_10850	ENOG4105U0R	haloacid dehalogenase-like hydrolase
E9099_10860	ENOG4105D1H	recombination factor protein RarA
E9099_10870	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E9099_10885	ENOG4105C27	TonB-dependent Receptor Plug
E9099_10895	ENOG4105C27	TonB-dependent Receptor Plug
E9099_10905	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E9099_10910	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
E9099_10915	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E9099_10920	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
E9099_10925	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E9099_10930	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E9099_10935	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E9099_10940	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E9099_10945	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E9099_10950	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
E9099_10955	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E9099_10960	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E9099_10965	ENOG4105WNB	50s ribosomal protein l29
E9099_10970	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E9099_10975	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E9099_10980	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E9099_10985	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E9099_10990	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E9099_10995	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E9099_11000	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E9099_11005	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E9099_11010	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E9099_11015	ENOG41084HK	50S ribosomal protein L30
E9099_11020	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E9099_11025	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E9099_11030	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E9099_11035	ENOG410864M	50S ribosomal protein L36
E9099_11040	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E9099_11045	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E9099_11050	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E9099_11055	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E9099_11060	ENOG4108ZT0	50S ribosomal protein l17
E9099_11065	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E9099_11070	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E9099_11115	ENOG4105FQP	Beta-lactamase
E9099_11155	ENOG4105DQ6	Transposase
E9099_11195	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
E9099_11210	ENOG4105FE9	pseudouridine synthase
E9099_11220	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
E9099_11235	ENOG4105D7A	ATP-binding protein
E9099_11240	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E9099_11250	ENOG4105CAQ	asparagine synthetase
E9099_11255	ENOG4105BZU	Histidine kinase
E9099_11260	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E9099_11280	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E9099_11290	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E9099_11295	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E9099_11300	ENOG4105C8N	cysteinyl-tRNA synthetase
E9099_11305	ENOG4105EUJ	GTP cyclohydrolase i
E9099_11330	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E9099_11340	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
E9099_11400	ENOG4107QUV	Domain protein
E9099_11405	ENOG4105C1G	acyl-Coa dehydrogenase
E9099_11415	ENOG4105D82	Glutamate dehydrogenase
E9099_11420	ENOG4105DN9	Na H antiporter
E9099_11425	ENOG4105M8K	biopolymer transport protein
E9099_11430	ENOG4109015	Biopolymer transport protein exbD tolR
E9099_11440	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E9099_11450	ENOG4105CFG	Acts as a chaperone (By similarity)
E9099_11465	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E9099_11480	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E9099_11485	ENOG4105BZ1	(ABC) transporter
E9099_11505	ENOG4105EEI	dihydropteroate synthase
E9099_11520	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E9099_11525	ENOG4105CP7	Triose-phosphate isomerase
E9099_11530	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E9099_11575	ENOG4108K8S	endonuclease I
E9099_11595	ENOG4107R5B	glutamine synthetase
E9099_11605	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E9099_11630	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E9099_11640	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
E9099_11645	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
E9099_11665	ENOG4105D5P	Methylmalonyl-coA mutase
E9099_11675	ENOG4108AEY	RNA polymerase sigma factor
E9099_11690	ENOG4108YXU	transcriptional regulator AsnC family
E9099_11695	ENOG4105ECQ	AraC Family Transcriptional Regulator
E9099_11705	ENOG4107XZQ	multidrug resistance protein
E9099_11715	ENOG41083GQ	Protein CrcB homolog
E9099_11745	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E9099_11780	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
E9099_11785	ENOG4108RWN	rrna methyltransferase
E9099_11800	ENOG4105VC4	domain protein
E9099_11805	ENOG4105CI2	imidazolone-5-propionate hydrolase
E9099_11810	ENOG4105CD3	dihydroorotase
E9099_11825	ENOG4105CIN	aminoacyl-histidine dipeptidase
E9099_11840	ENOG4105EMK	carboxylate amino acid amine transporter
E9099_11845	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E9099_11910	ENOG4105DQ6	Transposase
E9099_11940	ENOG4105EI2	Pseudouridine synthase
E9099_11950	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
E9099_11965	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E9099_11970	ENOG4105VEQ	Cold shock protein
E9099_11975	ENOG4105VEQ	Cold shock protein
E9099_11990	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E9099_12000	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E9099_12015	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E9099_12025	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
E9099_12045	ENOG4105C3F	Signal peptidase i
E9099_12050	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E9099_12060	ENOG4105FA0	parb-like partition protein
E9099_12065	ENOG4107QJE	Chromosome Partitioning Protein
E9099_12070	ENOG4108M26	parallel beta-helix repeat protein
E9099_12085	ENOG4105D5P	Methylmalonyl-coA mutase
E9099_12095	ENOG4105CMN	Methylmalonyl-coA mutase
E9099_12140	ENOG4105C3M	thioredoxin reductase
E9099_12200	ENOG4105C5Q	Transcriptional regulator
E9099_12205	ENOG4108RMU	ferritin dps family protein
E9099_12220	ENOG4105EN6	Membrane
E9099_12320	ENOG4105DGW	oligopeptidase A
E9099_12325	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E9099_12380	ENOG4108HRK	Histidine kinase
E9099_12390	ENOG4105DY9	regulatoR
E9099_12415	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E9099_12425	ENOG4108AEY	RNA polymerase sigma factor
E9099_12450	ENOG4105F5Q	hydrolase, family 8
E9099_12490	ENOG4105C1G	acyl-Coa dehydrogenase
E9099_12495	ENOG4105CHU	acetyl-coa acetyltransferase
E9099_12510	ENOG4108IQE	Amp-dependent synthetase and ligase
E9099_12520	ENOG4108ETH	Formylglycinamide ribotide synthetase
E9099_12625	ENOG4105EMN	RNA polymerase sigma factor
E9099_12630	ENOG4105BZ1	(ABC) transporter
E9099_12640	ENOG4105CKK	Glycosyl transferase, family 2
E9099_12650	ENOG41081WG	50s ribosomal protein l31
E9099_12675	ENOG4105DEF	Extracellular solute-binding protein, family 5
E9099_12680	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E9099_12700	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E9099_12710	ENOG4105VG0	50S ribosomal protein l34
E9099_12715	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E9099_12735	ENOG4105CGY	Dna recombination protein
E9099_12740	ENOG4105E0A	ABC, transporter
E9099_12745	ENOG4105EHG	Permease protein
E9099_12800	ENOG4107QTF	adenylosuccinate lyase
E9099_12820	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E9099_12835	ENOG4105D6J	arsenicaL-resistance protein
E9099_12845	ENOG41080HT	Transcriptional regulator, arsr family
E9099_12880	ENOG4105D7N	magnesium and cobalt transport protein CorA
E9099_12895	ENOG4108Z03	MAF-like protein
E9099_12940	ENOG4105CRE	cytochrome C
E9099_12955	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E9099_12965	ENOG4105C28	cystathionine
E9099_12970	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
E9099_12975	ENOG4105FJR	Lmbe family
E9099_13045	ENOG4105D9U	N-acetyltransferase
E9099_13075	ENOG4105X54	addiction module antidote protein
E9099_13085	ENOG4106NZI	LysR family Transcriptional regulator
E9099_13175	ENOG4105C5H	ABC transporter
E9099_13195	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E9099_13300	ENOG4105KNA	-acetyltransferase
E9099_13335	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E9099_13375	ENOG4108VAC	response regulator
E9099_13390	ENOG4105CBC	glutamate synthase
E9099_13405	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E9099_13440	ENOG4107RKG	DJ-1/PfpI family
E9099_13460	ENOG4105CPP	Dehydrogenase, E1 component
E9099_13470	ENOG4108URH	decarboxylase
E9099_13495	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
E9099_13505	ENOG4105EXC	Acyl-transferase
E9099_13510	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E9099_13530	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E9099_13535	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E9099_13565	ENOG4105CVR	type I restriction-modification system
E9099_13575	ENOG4105CVR	type I restriction-modification system
E9099_13590	ENOG4105DZR	Type I site-specific deoxyribonuclease
E9099_13635	ENOG4107Q25	Serine Threonine protein kinase
E9099_13685	ENOG4105BZU	Histidine kinase
E9099_13720	ENOG4108JUA	Transcriptional regulator
E9099_13755	ENOG4105BZU	Histidine kinase
E9099_13760	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E9099_13765	ENOG4105D82	Glutamate dehydrogenase
E9099_13795	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E9099_13895	ENOG4105NVB	glycoside hydrolase, family 19
E9099_14000	ENOG4108QBX	(LipO)protein
E9099_14055	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
E9099_14060	ENOG4105C58	cytochrome c oxidase accessory protein ccog
E9099_14090	ENOG4105CY0	Metallo-Beta-Lactamase
E9099_14105	ENOG4107YZX	Universal stress protein
E9099_14120	ENOG4107URF	beta-phospho-glucomutase
E9099_14130	ENOG4105BZU	Histidine kinase
E9099_14135	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E9099_14150	ENOG4108VCT	Sulfite exporter TauE/SafE
E9099_14155	ENOG4107TPS	domain protein
E9099_14165	ENOG4105K63	Thioredoxin
E9099_14170	ENOG4105FQ6	thiopurine methyltransferase
E9099_14175	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E9099_14180	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E9099_14205	ENOG4105CJ1	ABC, transporter
E9099_14210	ENOG4105CJ1	ABC, transporter
E9099_14220	ENOG4107QWP	ABC-2 type transporter
E9099_14225	ENOG4105CJ1	ABC, transporter
E9099_14235	ENOG4108RWI	nicotinamidase
E9099_14240	ENOG4105DAP	Nicotinate phosphoribosyltransferase
E9099_14255	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E9099_14270	ENOG4105CUC	YeeE YedE family protein
E9099_14290	ENOG4105D05	Receptor
E9099_14415	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E9099_14445	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E9099_14470	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
E9099_14475	ENOG4105C9A	Phoh family
E9099_14480	ENOG4107QWK	SAICAR synthetase
E9099_14495	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E9099_14530	ENOG4105BZG	amino acid carrier protein
E9099_14540	ENOG41075H3	AraC family transcriptional regulator
E9099_14545	ENOG4105C26	Dehydrogenase
E9099_14570	ENOG4107QN1	sodium solute
E9099_14580	ENOG4105BZU	Histidine kinase
E9099_14585	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E9099_14595	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E9099_14600	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E9099_14605	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
E9099_14610	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
E9099_14640	ENOG4105BZU	Histidine kinase
E9099_14650	ENOG4105KK6	nuclease
E9099_14675	ENOG4105CA0	peroxidase
E9099_14685	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
E9099_14690	ENOG4105C2C	drug resistance transporter, Bcr CflA
E9099_14725	ENOG4105BZ1	(ABC) transporter
E9099_14730	ENOG4107QX3	carboxylase
E9099_14735	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E9099_14740	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
E9099_14750	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
E9099_14755	ENOG41081VB	Hydrolase
E9099_14765	ENOG4105CN9	Peptidase m42 family protein
E9099_14775	ENOG4108UT2	hemolysin iii
E9099_14785	ENOG41067HS	methyltransferase
E9099_14790	ENOG4105E6M	Sulphatase-modifying factor protein
E9099_14815	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
E9099_14830	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E9099_14835	ENOG4105C8Y	Acetylornithine aminotransferase
E9099_14860	ENOG4107QI6	Cysteine desulfurase
E9099_14905	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
E9099_14910	ENOG4105BZU	Histidine kinase
E9099_14915	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
E9099_14920	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E9099_14930	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E9099_14935	ENOG4107QN2	dihydrolipoyl dehydrogenase
E9099_14940	ENOG4105CEP	NADH dehydrogenase
E9099_14950	ENOG4105E0X	reductase
E9099_14955	ENOG4105E0X	reductase
E9099_14960	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E9099_14965	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E9099_14970	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E9099_14985	ENOG4105DEU	major facilitator superfamily
E9099_14995	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
E9099_15010	ENOG4105EYW	Ion transport protein
E9099_15015	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
E9099_15040	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E9099_15060	ENOG4105KA0	thioesterase Superfamily protein
E9099_15065	ENOG4105E4F	Isochorismate synthase
E9099_15070	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
E9099_15080	ENOG4105QNR	S1 RNA binding domain protein
E9099_15100	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
E9099_15105	ENOG4107W2A	UPF0173 metal-dependent hydrolase
E9099_15110	ENOG4107GJV	short-chain dehydrogenase reductase
E9099_15115	ENOG4105DTQ	mandelate racemase muconate lactonizing
E9099_15120	ENOG4107FCW	Abortive infection protein
E9099_15130	ENOG4105C27	TonB-dependent Receptor Plug
E9099_15140	ENOG4107QX3	carboxylase
E9099_15145	ENOG4105Q8W	reductase
E9099_15150	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
E9099_15165	ENOG4105C5H	ABC transporter
E9099_15180	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
E9099_15245	ENOG4105CI2	imidazolone-5-propionate hydrolase
E9099_15255	ENOG4105C9Q	fumarate hydratase class II
E9099_15270	ENOG4105K89	arsenate reductase
E9099_15275	ENOG4105K89	arsenate reductase
E9099_15290	ENOG4105UYK	outer membrane protein a
E9099_15295	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E9099_15310	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E9099_15365	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E9099_15375	ENOG4105CSM	endonuclease III
E9099_15380	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E9099_15385	ENOG4105CDY	transcriptional regulatory protein
E9099_15390	ENOG4105CN1	protease
E9099_15395	ENOG4105KZX	Pterin carbinolamine dehydratase
E9099_15405	ENOG4105CSV	Glutaminase
E9099_15410	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E9099_15420	ENOG4105HMI	Membrane
E9099_15525	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E9099_15595	ENOG4105DKW	ABC transporter
E9099_15685	ENOG4105DS4	PAS PAC sensor Signal transduction histidine kinase
E9099_15755	ENOG4108JQ1	Dehydrogenase
E9099_15760	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E9099_15770	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E9099_15775	ENOG4105C27	TonB-dependent Receptor Plug
E9099_15780	ENOG4105C3G	gtp-binding protein
E9099_15790	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
E9099_15795	ENOG4105DF5	DNA topoisomerase IV, subunit A
E9099_15800	ENOG4107MM9	BNR Asp-box repeat-containing protein
E9099_15830	ENOG4105EE5	Membrane protein terC
E9099_15850	ENOG4108VVK	transcriptional Regulator, AsnC
E9099_15860	ENOG4105D49	3-dehydroquinate synthase
E9099_15865	ENOG41062BK	proline dehydrogenase
E9099_15890	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E9099_15895	ENOG4105DCI	Phosphohydrolase
E9099_15900	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E9099_15905	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E9099_15910	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E9099_15915	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E9099_15920	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E9099_15930	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E9099_15940	ENOG4105CHR	reductase
E9099_15960	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E9099_15965	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E9099_15970	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E9099_15975	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
E9099_15985	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E9099_15995	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E9099_16000	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E9099_16015	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E9099_16020	ENOG4108RMU	ferritin dps family protein
E9099_16025	ENOG4105D64	Mechanosensitive ion channel
E9099_16070	ENOG4105VEQ	Cold shock protein
E9099_16075	ENOG4105VEQ	Cold shock protein
E9099_16090	ENOG4105C1J	atp-dependent rna helicase
E9099_16095	ENOG4105C1J	atp-dependent rna helicase
E9099_16110	ENOG4105C26	Dehydrogenase
E9099_16125	ENOG4105VEQ	Cold shock protein
E9099_16130	ENOG4105VEQ	Cold shock protein
E9099_16135	ENOG4105VEQ	Cold shock protein
E9099_16145	ENOG4108I6A	alcohol dehydrogenase
E9099_16150	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
E9099_16155	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E9099_16170	ENOG4107Z3H	Transcriptional regulator, TetR family
E9099_16200	ENOG4105CNN	ABC, transporter
E9099_16205	ENOG4105DEI	Mannitol dehydrogenase
E9099_16210	ENOG4105D7K	pfkb domain protein
E9099_16215	ENOG4108XG2	Histidine kinase
E9099_16220	ENOG4105WH1	Two component transcriptional regulator luxr family
E9099_16235	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E9099_16240	ENOG4108Z9K	Osmotically inducible protein
E9099_16245	ENOG4105DQ4	alcohol dehydrogenase
E9099_16260	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E9099_16265	ENOG4105C19	ABC transporter
E9099_16270	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E9099_16280	ENOG4105DHU	Bile acid
E9099_16285	ENOG4108HRK	Histidine kinase
E9099_16290	ENOG4108NEV	two component transcriptional regulator, LytTR family
E9099_16325	ENOG4105C94	Transporter
E9099_16335	ENOG4108RCM	Nitroreductase
E9099_16365	ENOG4105NF4	modulator of drug activity
E9099_16375	ENOG4105KVH	Transcriptional regulator
E9099_16380	ENOG4108RCM	Nitroreductase
E9099_16395	ENOG4107FQX	Alpha-acetolactate decarboxylase
E9099_16400	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
E9099_16415	ENOG4105CIS	alcohol dehydrogenase
E9099_16435	ENOG4105CIS	alcohol dehydrogenase
E9099_16450	ENOG4105D0C	transport protein
E9099_16455	ENOG4105CEB	Aspartate aminotransferase
E9099_16465	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
E9099_16475	ENOG4105VEQ	Cold shock protein
E9099_16510	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
E9099_16515	ENOG4105C59	p-type ATPase
E9099_16530	ENOG4108IJF	Heavy metal efflux pump, CzcA
E9099_16540	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E9099_16580	ENOG4105DEN	Luciferase family
E9099_16605	ENOG4105D41	biosynthesis protein thiH
E9099_16610	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E9099_16615	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E9099_16620	ENOG4105DWF	phosphomethylpyrimidine kinase
E9099_16630	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
E9099_16820	ENOG4105CUY	Mechanosensitive ion channel
E9099_16850	ENOG4105CPP	Dehydrogenase, E1 component
E9099_16870	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
E9099_16885	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E9099_16895	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
E9099_16930	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E9099_17050	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
E9099_17145	ENOG4105C98	muts2 protein
E9099_17150	ENOG4105VC4	domain protein
E9099_17160	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
E9099_17175	ENOG4105KHC	sulfurtransferase
E9099_17190	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E9099_17205	ENOG4105CQB	FAD linked oxidase domain protein
E9099_17215	ENOG4105CPK	Glycosyl transferase (Group 1
E9099_17220	ENOG4105D17	glycoside hydrolase, family 3 domain protein
E9099_17230	ENOG4105EAC	phosphoserine phosphatase
E9099_17240	ENOG4105DF6	Fe-S oxidoreductase
E9099_17250	ENOG4105DF6	Fe-S oxidoreductase
E9099_17260	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E9099_17280	ENOG4108Z5K	methylglyoxal synthase
E9099_17295	ENOG4105CTQ	phosphohexokinase
E9099_17305	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E9099_17310	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E9099_17595	ENOG4107QWR	cellulase (EC 3.2.1.4)
E9099_17615	ENOG4105CTJ	Metal Dependent Phosphohydrolase
E9099_17620	ENOG4105CHU	acetyl-coa acetyltransferase
E9099_17625	ENOG4107SN7	NLP P60 protein
E9099_17650	ENOG4105C84	Histidine ammonia-lyase
E9099_17655	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E9099_17660	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E9099_17665	ENOG4105CFH	Aspartokinase
E9099_17670	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
E9099_17675	ENOG4105D98	threonine synthase
E9099_17710	ENOG4108YIQ	Alpha beta hydrolase
E9099_17765	ENOG4105D29	Helix-turn-helix type 11 domain protein
E9099_17805	ENOG4105EUJ	GTP cyclohydrolase i
E9099_17810	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E9099_17820	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E9099_17840	ENOG4105BZU	Histidine kinase
E9099_17860	ENOG4105CD3	dihydroorotase
E9099_17880	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
E9099_17895	ENOG4107RJC	Iron-containing alcohol dehydrogenase
E9099_17910	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
E9099_17915	ENOG4105C7H	Helicase, RecD TraA family
E9099_17930	ENOG4106H78	methyltransferase
E9099_17940	ENOG4105C6E	dna polymerase iii
E9099_17965	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
E9099_17985	ENOG4105CDV	Ompa motb domain protein
E9099_17990	ENOG4105K4I	Scp-like extracellular
E9099_17995	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
E9099_18005	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
E9099_18015	ENOG4105CXT	aspartate transcarbamylase
E9099_18020	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
E9099_18025	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E9099_18030	ENOG4108I7Y	domain protein
E9099_18035	ENOG4105CAT	Cytidine monophosphate kinase
E9099_18045	ENOG4105EA8	2-Nitropropane dioxygenase
E9099_18050	ENOG4105CFG	Acts as a chaperone (By similarity)
E9099_18055	ENOG4105EJQ	L-serine dehydratase
E9099_18060	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
E9099_18070	ENOG4105C26	Dehydrogenase
E9099_18090	ENOG4105C0P	Mg chelatase subunit ChlI
E9099_18105	ENOG4105CPN	adenine deaminase
E9099_18115	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E9099_18135	ENOG4105C1J	atp-dependent rna helicase
E9099_18250	ENOG4107QN2	dihydrolipoyl dehydrogenase
E9099_18260	ENOG4105EW9	transcriptional regulator AsnC family
E9099_18275	ENOG4105DFD	Na H antiporter
E9099_18280	ENOG4105D3R	alkyl hydroperoxide reductase
E9099_18285	ENOG4105N6Y	Thioredoxin
E9099_18310	ENOG4105E08	Glycoside hydrolase, family 9
E9099_18315	ENOG4105E1F	short-chain dehydrogenase reductase
E9099_18320	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
E9099_18350	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
E9099_18355	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
E9099_18360	ENOG41080IJ	Diacylglycerol kinase
E9099_18365	ENOG4105CNU	cell division protein FtsK
E9099_18380	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E9099_18385	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E9099_18395	ENOG4108RCM	Nitroreductase
E9099_18420	ENOG4105C0B	DNA polymerase III (alpha subunit)
E9099_18425	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E9099_18480	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
E9099_18490	ENOG4105F44	Two component transcriptional regulator, winged helix family
E9099_18505	ENOG4105DZR	Type I site-specific deoxyribonuclease
E9099_18545	ENOG4105CHR	reductase
E9099_18550	ENOG4107YZX	Universal stress protein
E9099_18590	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E9099_18595	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E9099_18630	ENOG4105CNG	UPF0061 protein
E9099_18635	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E9099_18650	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E9099_18660	ENOG4105E1F	short-chain dehydrogenase reductase
E9099_18690	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E9099_18705	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E9099_18710	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
E9099_18725	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E9099_18745	ENOG4105DWT	malate dehydrogenase (quinone)
E9099_18750	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
E9099_18770	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E9099_18870	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E9099_18875	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
E9099_18880	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E9099_18890	ENOG4105DFA	alanine racemase domain protein
E9099_18900	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
E9099_18910	ENOG4105EYW	Ion transport protein
E9099_18915	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
E9099_18930	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
E9099_18950	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
E9099_18955	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E9099_18980	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E9099_18995	ENOG4105CGH	5'-nucleotidase
E9099_19005	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E9099_19015	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E9099_19030	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E9099_19110	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein