locus-tag	class	description
HI798_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HI798_00010	COG0592	DNA-directed DNA polymerase activity
HI798_00125	COG3781	membrane
HI798_00155	COG1126	abc transporter atp-binding protein
HI798_00160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI798_00175	COG0745	RESPONSE REGULATOR receiver
HI798_00180	COG0642	Histidine kinase
HI798_00195	COG2814	Major facilitator Superfamily
HI798_00215	COG1959	2 iron, 2 sulfur cluster binding
HI798_00240	COG0745	RESPONSE REGULATOR receiver
HI798_00245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HI798_00265	COG2203	Gaf domain
HI798_00265	COG3706	GGDEF domain
HI798_00265	COG4251	negative regulation of phosphorylation
HI798_00265	COG5001	Diguanylate cyclase
HI798_00275	COG2205	protein histidine kinase activity
HI798_00280	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HI798_00285	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HI798_00290	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HI798_00325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HI798_00335	COG1116	anion transmembrane transporter activity
HI798_00345	COG1254	Belongs to the acylphosphatase family
HI798_00355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HI798_00360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HI798_00370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HI798_00375	COG2894	cell division
HI798_00380	COG0850	regulation of cytokinetic process
HI798_00385	COG0737	Belongs to the 5'-nucleotidase family
HI798_00395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HI798_00425	COG2154	pterin-4-alpha-carbinolamine dehydratase
HI798_00430	COG3186	Phenylalanine-4-hydroxylase
HI798_00445	COG2423	ornithine cyclodeaminase activity
HI798_00450	COG3047	cAMP biosynthetic process
HI798_00465	COG2217	Heavy metal translocating P-type atpase
HI798_00470	COG0789	Transcriptional regulator
HI798_00475	COG2267	carboxylic ester hydrolase activity
HI798_00540	COG3530	Putative quorum-sensing-regulated virulence factor
HI798_00545	COG0583	DNA-binding transcription factor activity
HI798_00565	COG0445	tRNA wobble uridine modification
HI798_00570	COG0357	Ribosomal RNA small subunit methyltransferase G
HI798_00575	COG1192	Involved in chromosome partitioning
HI798_00580	COG1475	DNA binding
HI798_00590	COG0356	it plays a direct role in the translocation of protons across the membrane
HI798_00600	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HI798_00605	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HI798_00610	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HI798_00615	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HI798_00620	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HI798_00625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HI798_00640	COG1832	CoA-binding protein
HI798_00660	COG0625	glutathione transferase activity
HI798_00690	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HI798_00695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HI798_00700	COG0506	proline dehydrogenase activity
HI798_00700	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HI798_00700	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HI798_00705	COG0683	leucine binding
HI798_00715	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HI798_00720	COG1297	OPT oligopeptide transporter protein
HI798_00725	COG1760	l-serine dehydratase
HI798_00730	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HI798_00730	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HI798_00735	COG0509	glycine decarboxylation via glycine cleavage system
HI798_00740	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HI798_00760	COG0210	DNA helicase
HI798_00780	COG2197	response regulator
HI798_00785	COG3916	Acyl-homoserine-lactone synthase
HI798_00795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HI798_00800	COG2084	Dehydrogenase
HI798_00805	COG3622	Belongs to the hyi family
HI798_00810	COG3960	tartronate-semialdehyde synthase activity
HI798_00815	COG0583	DNA-binding transcription factor activity
HI798_00830	COG1739	Uncharacterized protein family UPF0029
HI798_00840	COG1301	dicarboxylic acid transport
HI798_00845	COG4266	Belongs to the allantoicase family
HI798_00855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HI798_00880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HI798_00895	COG0792	nuclease activity
HI798_00910	COG0446	pyridine nucleotide-disulphide oxidoreductase
HI798_00920	COG4654	Cytochrome c, class I
HI798_00945	COG2010	Cytochrome c
HI798_00950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HI798_00955	COG0737	Belongs to the 5'-nucleotidase family
HI798_01030	COG3311	Transcriptional regulator
HI798_01090	COG3609	addiction module antidote protein, CC2985 family
HI798_01105	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HI798_01110	COG3039	Transposase
HI798_01220	COG2916	Histone family protein nucleoid-structuring protein H-NS
HI798_01325	COG3210	domain, Protein
HI798_01335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI798_01375	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
HI798_01380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI798_01385	COG0402	S-adenosylhomocysteine deaminase activity
HI798_01400	COG0529	Catalyzes the synthesis of activated sulfate
HI798_01415	COG0457	Tetratricopeptide repeat
HI798_01440	COG0493	'glutamate synthase
HI798_01450	COG3385	transposase activity
HI798_01455	COG1278	Cold shock
HI798_01475	COG3039	Transposase
HI798_01530	COG3706	GGDEF domain
HI798_01530	COG2203	Gaf domain
HI798_01530	COG5001	Diguanylate cyclase
HI798_01530	COG4251	negative regulation of phosphorylation
HI798_01545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HI798_01560	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_01570	COG0840	transmembrane signaling receptor activity
HI798_01595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HI798_01605	COG3284	Transcriptional regulator
HI798_01610	COG1012	belongs to the aldehyde dehydrogenase family
HI798_01615	COG4303	Ethanolamine ammonia lyase large subunit
HI798_01620	COG4302	ethanolamine ammonia-lyase activity
HI798_01625	COG2925	Exonuclease
HI798_01740	COG1522	sequence-specific DNA binding
HI798_01745	COG1404	Belongs to the peptidase S8 family
HI798_01770	COG0475	glutathione-regulated potassium exporter activity
HI798_01770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HI798_01795	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_01800	COG3385	transposase activity
HI798_01810	COG0745	RESPONSE REGULATOR receiver
HI798_01890	COG2917	probably involved in intracellular septation
HI798_01945	COG2916	Histone family protein nucleoid-structuring protein H-NS
HI798_02080	COG4695	Portal protein
HI798_02225	COG0863	Belongs to the N(4) N(6)-methyltransferase family
HI798_02320	COG0582	viral genome integration into host DNA
HI798_02360	COG2197	response regulator
HI798_02365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HI798_02400	COG2814	Major facilitator Superfamily
HI798_02405	COG0668	transmembrane transport
HI798_02425	COG0745	RESPONSE REGULATOR receiver
HI798_02430	COG2205	protein histidine kinase activity
HI798_02460	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HI798_02465	COG2336	PFAM SpoVT AbrB
HI798_02485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HI798_02500	COG0395	ABC-type sugar transport system, permease component
HI798_02510	COG3842	ATPase activity
HI798_02515	COG3842	ATPase activity
HI798_02525	COG1349	DNA-binding transcription factor activity
HI798_02575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HI798_02595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HI798_02600	COG0081	regulation of translation
HI798_02605	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HI798_02610	COG0222	ribosome binding
HI798_02615	COG0085	RNA polymerase activity
HI798_02620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HI798_02625	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HI798_02630	COG3234	Protein of unknown function (DUF1175)
HI798_02635	COG2373	Large extracellular alpha-helical protein
HI798_02640	COG5445	Predicted secreted protein (DUF2300)
HI798_02645	COG4676	Protein conserved in bacteria
HI798_02650	COG4676	Protein conserved in bacteria
HI798_02660	COG0514	ATP-dependent DNA helicase (RecQ)
HI798_02665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HI798_02670	COG0049	tRNA binding
HI798_02675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HI798_02680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HI798_02685	COG0051	transcription antitermination factor activity, RNA binding
HI798_02690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HI798_02695	COG0088	Forms part of the polypeptide exit tunnel
HI798_02700	COG0089	rRNA binding
HI798_02705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HI798_02710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HI798_02715	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HI798_02720	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HI798_02725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HI798_02730	COG0255	Belongs to the universal ribosomal protein uL29 family
HI798_02735	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HI798_02740	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HI798_02745	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HI798_02750	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HI798_02755	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HI798_02760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HI798_02765	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HI798_02770	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HI798_02775	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HI798_02780	COG1841	ribosomal large subunit assembly
HI798_02785	COG0200	Binds to the 23S rRNA
HI798_02790	COG0201	protein transport
HI798_02795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HI798_02800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HI798_02805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HI798_02810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HI798_02815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HI798_02820	COG0202	RNA polymerase activity
HI798_02825	COG0203	ribosomal protein L17
HI798_02835	COG4232	protein-disulfide reductase activity
HI798_02845	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HI798_02855	COG1333	cytochrome c biogenesis protein
HI798_02860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HI798_02880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HI798_02885	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HI798_02900	COG1965	Belongs to the frataxin family
HI798_02905	COG3385	transposase activity
HI798_02940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HI798_02945	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HI798_02950	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HI798_02955	COG3047	cAMP biosynthetic process
HI798_02965	COG0070	glutamate synthase
HI798_02965	COG0069	glutamate synthase activity
HI798_02965	COG0067	glutamate synthase
HI798_02980	COG1127	ABC transporter
HI798_02985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HI798_02990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HI798_03010	COG1131	(ABC) transporter
HI798_03015	COG0842	Transport permease protein
HI798_03025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HI798_03030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HI798_03035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HI798_03040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HI798_03045	COG0131	Imidazoleglycerol-phosphate dehydratase
HI798_03050	COG2095	MarC family integral membrane protein
HI798_03055	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HI798_03060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HI798_03065	COG0107	imidazoleglycerol-phosphate synthase activity
HI798_03070	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HI798_03075	COG0140	phosphoribosyl-ATP diphosphatase activity
HI798_03085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HI798_03090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HI798_03095	COG0805	protein transport
HI798_03100	COG3385	transposase activity
HI798_03105	COG3842	ATPase activity
HI798_03115	COG1840	ABC-type Fe3 transport system, periplasmic component
HI798_03135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_03140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HI798_03145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HI798_03150	COG1970	mechanosensitive ion channel activity
HI798_03155	COG0723	plastoquinol--plastocyanin reductase activity
HI798_03160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HI798_03165	COG2857	Cytochrome c1
HI798_03170	COG0625	glutathione transferase activity
HI798_03175	COG2969	positive regulation of protein catabolic process
HI798_03200	COG0405	Gamma-glutamyltransferase
HI798_03205	COG4774	siderophore transport
HI798_03210	COG3712	iron ion homeostasis
HI798_03220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HI798_03235	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HI798_03240	COG0488	(ABC) transporter
HI798_03260	COG2943	transferase activity, transferring hexosyl groups
HI798_03260	COG3416	Protein conserved in bacteria
HI798_03265	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HI798_03285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HI798_03290	COG2890	protein-(glutamine-N5) methyltransferase activity
HI798_03300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HI798_03305	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HI798_03315	COG0012	GTP binding
HI798_03340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HI798_03350	COG0604	alcohol dehydrogenase
HI798_03360	COG1289	transmembrane transporter activity
HI798_03375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HI798_03385	COG0134	indole-3-glycerol-phosphate synthase activity
HI798_03390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HI798_03400	COG0512	Glutamine amidotransferase of anthranilate synthase
HI798_03410	COG0546	phosphoglycolate phosphatase activity
HI798_03415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HI798_03420	COG2967	ApaG domain
HI798_03440	COG2050	protein possibly involved in aromatic compounds catabolism
HI798_03445	COG1024	Enoyl-CoA hydratase
HI798_03450	COG1024	Enoyl-CoA hydratase
HI798_03480	COG1473	amidohydrolase
HI798_03485	COG0747	negative chemotaxis
HI798_03490	COG0601	transmembrane transport
HI798_03495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HI798_03500	COG0444	Belongs to the ABC transporter superfamily
HI798_03505	COG4608	Belongs to the ABC transporter superfamily
HI798_03515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HI798_03515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HI798_03520	COG1105	Belongs to the carbohydrate kinase PfkB family
HI798_03525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HI798_03525	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HI798_03530	COG1609	Transcriptional regulator
HI798_03535	COG0243	molybdopterin cofactor binding
HI798_03545	COG0318	PFAM AMP-dependent synthetase and ligase
HI798_03550	COG0477	Major facilitator Superfamily
HI798_03555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_03560	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
HI798_03565	COG2001	Belongs to the MraZ family
HI798_03570	COG0275	rRNA processing
HI798_03585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HI798_03590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HI798_03595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HI798_03600	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HI798_03610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HI798_03615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HI798_03620	COG1181	Belongs to the D-alanine--D-alanine ligase family
HI798_03625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HI798_03640	COG0678	peroxiredoxin activity
HI798_03645	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HI798_03655	COG0739	heme binding
HI798_03660	COG0653	protein targeting
HI798_03665	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HI798_03675	COG0494	nUDIX hydrolase
HI798_03680	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HI798_03685	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HI798_03690	COG0237	dephospho-CoA kinase activity
HI798_03700	COG1459	type II secretion system
HI798_03710	COG4536	flavin adenine dinucleotide binding
HI798_03720	COG0142	geranyltranstransferase activity
HI798_03725	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HI798_03730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HI798_03735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HI798_03740	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HI798_03750	COG0494	nUDIX hydrolase
HI798_03755	COG0442	prolyl-tRNA aminoacylation
HI798_03760	COG0741	lytic transglycosylase activity
HI798_03770	COG2095	MarC family integral membrane protein
HI798_03780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HI798_03805	COG3023	N-Acetylmuramoyl-L-alanine amidase
HI798_03830	COG1522	sequence-specific DNA binding
HI798_03840	COG0840	transmembrane signaling receptor activity
HI798_03885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HI798_03890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HI798_03900	COG2264	protein methyltransferase activity
HI798_03910	COG0511	ligase activity, forming carbon-carbon bonds
HI798_03915	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HI798_03920	COG3118	belongs to the thioredoxin family
HI798_03930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HI798_03935	COG3150	esterase
HI798_03940	COG3161	chorismate lyase activity
HI798_03945	COG0557	exoribonuclease II activity
HI798_03955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HI798_03960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HI798_03975	COG0284	orotidine-5'-phosphate decarboxylase activity
HI798_03985	COG1058	Belongs to the CinA family
HI798_03985	COG1546	Belongs to the CinA family
HI798_03990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HI798_04000	COG0280	phosphate acetyltransferase
HI798_04000	COG0281	malic enzyme
HI798_04020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HI798_04030	COG0583	DNA-binding transcription factor activity
HI798_04035	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_04050	COG1129	ABC transporter
HI798_04070	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_04075	COG0800	Aldolase
HI798_04080	COG4948	Mandelate Racemase Muconate Lactonizing
HI798_04085	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HI798_04090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HI798_04105	COG0583	DNA-binding transcription factor activity
HI798_04110	COG0735	belongs to the Fur family
HI798_04115	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HI798_04120	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HI798_04125	COG0495	leucyl-tRNA aminoacylation
HI798_04135	COG1466	dna polymerase III delta subunit
HI798_04140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HI798_04155	COG2204	response regulator
HI798_04160	COG4191	Histidine kinase
HI798_04165	COG4191	Histidine kinase
HI798_04190	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HI798_04230	COG0482	sulfurtransferase activity
HI798_04235	COG0069	glutamate synthase activity
HI798_04240	COG0625	glutathione transferase activity
HI798_04250	COG3038	cytochrome b561
HI798_04255	COG2353	YceI-like domain
HI798_04260	COG2353	YceI-like domain
HI798_04265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HI798_04270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HI798_04275	COG1862	Preprotein translocase
HI798_04280	COG0343	queuine tRNA-ribosyltransferase activity
HI798_04285	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HI798_04290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HI798_04330	COG1522	sequence-specific DNA binding
HI798_04335	COG1473	amidohydrolase
HI798_04340	COG1819	glycosyl
HI798_04380	COG1278	Cold shock
HI798_04385	COG3385	transposase activity
HI798_04475	COG0783	Belongs to the Dps family
HI798_04480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HI798_04540	COG0386	Belongs to the glutathione peroxidase family
HI798_04560	COG1346	cytolysis
HI798_04565	COG1380	Effector of murein hydrolase LrgA
HI798_04570	COG0247	lactate metabolic process
HI798_04575	COG0277	FAD linked oxidase domain protein
HI798_04580	COG0277	FAD linked oxidase domain protein
HI798_04585	COG0583	DNA-binding transcription factor activity
HI798_04590	COG0277	FAD linked oxidase domain protein
HI798_04595	COG2096	Adenosyltransferase
HI798_04600	COG0668	transmembrane transport
HI798_04610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HI798_04615	COG0312	modulator of DNA gyrase
HI798_04620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HI798_04630	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HI798_04645	COG1404	Belongs to the peptidase S8 family
HI798_04655	COG0497	DNA recombination
HI798_04660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HI798_04665	COG1420	regulation of RNA biosynthetic process
HI798_04675	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HI798_04680	COG2986	histidine ammonia-lyase
HI798_04685	COG0010	Belongs to the arginase family
HI798_04690	COG1228	amidohydrolase
HI798_04695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HI798_04710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HI798_04720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HI798_04725	COG0443	Heat shock 70 kDa protein
HI798_04730	COG0484	heat shock protein binding
HI798_04735	COG0512	Glutamine amidotransferase of anthranilate synthase
HI798_04735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HI798_04740	COG1122	ATPase activity
HI798_04745	COG4662	Binding-protein-dependent transport system inner membrane component
HI798_04750	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HI798_04760	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HI798_04775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HI798_04780	COG0628	permease
HI798_04785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HI798_04800	COG2169	Transcriptional regulator
HI798_04800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HI798_04820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HI798_04820	COG2169	Transcriptional regulator
HI798_04825	COG0456	acetyltransferase
HI798_04830	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HI798_04835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HI798_04840	COG3008	intermembrane lipid transfer
HI798_04855	COG0586	Pfam SNARE associated Golgi protein
HI798_04865	COG0728	peptidoglycan biosynthetic process
HI798_04870	COG0268	Binds directly to 16S ribosomal RNA
HI798_04880	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HI798_04885	COG0137	argininosuccinate synthase activity
HI798_04890	COG3123	guanosine phosphorylase activity
HI798_04900	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HI798_04905	COG1666	GTP binding
HI798_04915	COG2366	antibiotic biosynthetic process
HI798_04920	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HI798_04930	COG4974	Belongs to the 'phage' integrase family
HI798_04945	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HI798_04950	COG0802	atpase or kinase
HI798_04955	COG0860	N-Acetylmuramoyl-L-alanine amidase
HI798_04965	COG0583	DNA-binding transcription factor activity
HI798_04985	COG0563	adenylate kinase activity
HI798_04990	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HI798_04995	COG2835	tetraacyldisaccharide 4'-kinase activity
HI798_05000	COG1663	tetraacyldisaccharide 4'-kinase activity
HI798_05010	COG0811	peptide transport
HI798_05015	COG1570	exodeoxyribonuclease VII activity
HI798_05020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HI798_05065	COG2610	gluconate transmembrane transporter activity
HI798_05115	COG1473	amidohydrolase
HI798_05150	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_05155	COG2321	neutral zinc metallopeptidase
HI798_05170	COG2259	Doxx family
HI798_05180	COG0583	DNA-binding transcription factor activity
HI798_05185	COG0583	DNA-binding transcription factor activity
HI798_05205	COG1858	cytochrome C peroxidase
HI798_05240	COG1278	Cold shock
HI798_05245	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HI798_05250	COG0542	response to heat
HI798_05255	COG0756	dUTP diphosphatase activity
HI798_05260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HI798_05265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HI798_05275	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HI798_05280	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HI798_05285	COG0196	riboflavin kinase activity
HI798_05290	COG0784	Response regulator, receiver
HI798_05290	COG5002	protein histidine kinase activity
HI798_05295	COG2197	response regulator
HI798_05300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HI798_05305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HI798_05305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HI798_05315	COG1511	domain protein
HI798_05315	COG3264	Mechanosensitive ion channel
HI798_05325	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HI798_05335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HI798_05340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HI798_05345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HI798_05350	COG2003	Belongs to the UPF0758 family
HI798_05355	COG1047	Peptidyl-prolyl cis-trans
HI798_05360	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HI798_05395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HI798_05430	COG2084	Dehydrogenase
HI798_05440	COG0583	DNA-binding transcription factor activity
HI798_05450	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HI798_05460	COG0175	sulfate reduction
HI798_05470	COG2895	sulfate adenylyltransferase (ATP) activity
HI798_05500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HI798_05515	COG3385	transposase activity
HI798_05520	COG0129	dihydroxy-acid dehydratase activity
HI798_05525	COG0583	DNA-binding transcription factor activity
HI798_05530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HI798_05560	COG4206	TonB-dependent receptor
HI798_05570	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HI798_05575	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HI798_05580	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HI798_05590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HI798_05600	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HI798_05610	COG1492	cobalamin metabolic process
HI798_05630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HI798_05635	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HI798_05650	COG2911	Protein conserved in bacteria
HI798_05660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HI798_05660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HI798_05665	COG3047	cAMP biosynthetic process
HI798_05665	COG2885	chlorophyll binding
HI798_05670	COG0489	protein tyrosine kinase activity
HI798_05700	COG0243	molybdopterin cofactor binding
HI798_05700	COG3383	formate dehydrogenase (NAD+) activity
HI798_05705	COG0437	4 iron, 4 sulfur cluster binding
HI798_05725	COG2032	superoxide dismutase activity
HI798_05730	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HI798_05735	COG0717	Belongs to the dCTP deaminase family
HI798_05740	COG1982	Orn Lys Arg decarboxylase major
HI798_05780	COG0165	Argininosuccinate lyase
HI798_05805	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HI798_05810	COG0181	hydroxymethylbilane synthase activity
HI798_05835	COG2271	Major facilitator Superfamily
HI798_05850	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HI798_05890	COG0492	ferredoxin-NADP+ reductase activity
HI798_05895	COG1674	ftsk spoiiie
HI798_05900	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HI798_05910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HI798_05915	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HI798_05925	COG0582	viral genome integration into host DNA
HI798_05940	COG2814	Major facilitator Superfamily
HI798_05950	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_05955	COG1522	sequence-specific DNA binding
HI798_05965	COG1522	sequence-specific DNA binding
HI798_05975	COG2814	Major facilitator Superfamily
HI798_05990	COG2197	response regulator
HI798_06045	COG2165	general secretion pathway protein
HI798_06115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HI798_06130	COG3039	Transposase
HI798_06170	COG1253	flavin adenine dinucleotide binding
HI798_06225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI798_06240	COG0765	amino acid transport
HI798_06245	COG0765	amino acid transport
HI798_06250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HI798_06260	COG1414	Transcriptional regulator
HI798_06270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HI798_06275	COG0183	Belongs to the thiolase family
HI798_06285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HI798_06290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HI798_06305	COG0411	ABC transporter
HI798_06315	COG0683	leucine binding
HI798_06330	COG2342	PFAM TM1410 hypothetical-related protein
HI798_06340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HI798_06355	COG0525	valine-tRNA ligase activity
HI798_06360	COG0210	DNA helicase
HI798_06370	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HI798_06380	COG1611	Belongs to the LOG family
HI798_06385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HI798_06385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HI798_06390	COG1252	NADH dehydrogenase
HI798_06395	COG0412	Dienelactone hydrolase
HI798_06405	COG3385	transposase activity
HI798_06425	COG1722	exodeoxyribonuclease VII activity
HI798_06430	COG0142	geranyltranstransferase activity
HI798_06435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HI798_06440	COG1469	GTP cyclohydrolase I activity
HI798_06445	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HI798_06450	COG2081	HI0933 family
HI798_06455	COG1610	YqeY-like protein
HI798_06475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HI798_06485	COG0426	domain, Protein
HI798_06485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HI798_06490	COG0513	Belongs to the DEAD box helicase family
HI798_06495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HI798_06500	COG0583	DNA-binding transcription factor activity
HI798_06505	COG1741	Belongs to the pirin family
HI798_06545	COG1132	(ABC) transporter
HI798_06565	COG1530	ribonuclease E activity
HI798_06570	COG0424	maF-like protein
HI798_06575	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HI798_06580	COG0799	negative regulation of ribosome biogenesis
HI798_06590	COG0408	coproporphyrinogen oxidase activity
HI798_06595	COG0151	Belongs to the GarS family
HI798_06600	COG0217	transcriptional regulatory protein
HI798_06605	COG0433	COG0433 Predicted ATPase
HI798_06610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HI798_06615	COG0697	spore germination
HI798_06620	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_06625	COG1803	Methylglyoxal synthase
HI798_06680	COG1129	ABC transporter
HI798_06685	COG2814	Major facilitator Superfamily
HI798_06690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HI798_06695	COG1984	allophanate hydrolase subunit 2
HI798_06700	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HI798_06715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HI798_06720	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HI798_06735	COG1234	tRNA 3'-trailer cleavage
HI798_06745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HI798_06750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HI798_06755	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HI798_06765	COG0515	serine threonine protein kinase
HI798_06765	COG4991	sh3 domain protein
HI798_06765	COG3064	Membrane
HI798_06770	COG1561	YicC-like family, N-terminal region
HI798_06775	COG0194	GDP metabolic process
HI798_06780	COG1758	RNA polymerase activity
HI798_06785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HI798_06815	COG1652	LysM domain
HI798_06825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HI798_06850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HI798_06855	COG3842	ATPase activity
HI798_06865	COG3039	Transposase
HI798_06875	COG1733	regulation of RNA biosynthetic process
HI798_06880	COG0166	Belongs to the GPI family
HI798_06880	COG0166	Belongs to the GPI family
HI798_06885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_06905	COG3039	Transposase
HI798_06920	COG0246	Mannitol dehydrogenase
HI798_06925	COG1070	Carbohydrate kinase
HI798_06930	COG2390	Transcriptional regulator
HI798_06940	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HI798_06945	COG0308	aminopeptidase N
HI798_06955	COG0281	malic enzyme
HI798_06955	COG0280	phosphate acetyltransferase
HI798_06965	COG3195	allantoin biosynthetic process
HI798_06965	COG3648	Uricase
HI798_06980	COG2233	PERMEase
HI798_06990	COG2351	hydroxyisourate hydrolase activity
HI798_07010	COG3039	Transposase
HI798_07015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI798_07020	COG2271	Major facilitator Superfamily
HI798_07025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HI798_07030	COG1012	belongs to the aldehyde dehydrogenase family
HI798_07040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_07050	COG1126	abc transporter atp-binding protein
HI798_07055	COG0765	amino acid transport
HI798_07060	COG0765	amino acid transport
HI798_07070	COG2186	Transcriptional regulator
HI798_07085	COG2119	membrane
HI798_07090	COG0402	S-adenosylhomocysteine deaminase activity
HI798_07095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HI798_07105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HI798_07130	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HI798_07155	COG1309	transcriptional regulator
HI798_07165	COG0438	transferase activity, transferring glycosyl groups
HI798_07200	COG0028	Belongs to the TPP enzyme family
HI798_07210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HI798_07215	COG0688	phosphatidylethanolamine metabolic process
HI798_07220	COG1183	phosphatidylcholine synthase activity
HI798_07225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HI798_07235	COG0683	leucine binding
HI798_07240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HI798_07245	COG1185	polyribonucleotide nucleotidyltransferase activity
HI798_07260	COG0149	triose-phosphate isomerase activity
HI798_07265	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HI798_07275	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HI798_07280	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HI798_07285	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HI798_07290	COG0649	NAD binding
HI798_07305	COG1034	ATP synthesis coupled electron transport
HI798_07310	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HI798_07315	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HI798_07325	COG0713	ATP synthesis coupled electron transport
HI798_07340	COG1007	ATP synthesis coupled electron transport
HI798_07360	COG1960	acyl-CoA dehydrogenase activity
HI798_07365	COG1960	acyl-CoA dehydrogenase activity
HI798_07370	COG2030	dehydratase
HI798_07370	COG1012	belongs to the aldehyde dehydrogenase family
HI798_07405	COG0829	nickel cation binding
HI798_07410	COG0831	urea catabolic process
HI798_07420	COG0832	Belongs to the urease beta subunit family
HI798_07425	COG0804	urea catabolic process
HI798_07430	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HI798_07435	COG0830	nickel cation binding
HI798_07440	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HI798_07465	COG0625	glutathione transferase activity
HI798_07470	COG1960	acyl-CoA dehydrogenase activity
HI798_07500	COG1024	Enoyl-CoA hydratase
HI798_07505	COG1250	3-hydroxyacyl-CoA dehydrogenase
HI798_07510	COG0625	glutathione transferase activity
HI798_07515	COG0436	Aminotransferase
HI798_07525	COG3022	response to hydroperoxide
HI798_07530	COG2866	Carboxypeptidase
HI798_07540	COG0747	negative chemotaxis
HI798_07555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HI798_07580	COG0039	L-malate dehydrogenase activity
HI798_07585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI798_07595	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HI798_07600	COG1053	succinate dehydrogenase
HI798_07605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HI798_07610	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HI798_07615	COG0372	Belongs to the citrate synthase family
HI798_07620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HI798_07625	COG0066	3-isopropylmalate dehydratase activity
HI798_07630	COG0473	3-isopropylmalate dehydrogenase activity
HI798_07650	COG0101	tRNA pseudouridine synthase activity
HI798_07655	COG0135	phosphoribosylanthranilate isomerase activity
HI798_07660	COG0133	tryptophan synthase activity
HI798_07670	COG0159	tryptophan synthase activity
HI798_07675	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HI798_07680	COG0285	dihydrofolate synthase activity
HI798_07700	COG0842	Transport permease protein
HI798_07705	COG1131	(ABC) transporter
HI798_07735	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HI798_07780	COG1301	dicarboxylic acid transport
HI798_07785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HI798_07800	COG0697	spore germination
HI798_07805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HI798_07810	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HI798_07820	COG3039	Transposase
HI798_07825	COG3501	Rhs element vgr protein
HI798_07835	COG3039	Transposase
HI798_07850	COG4695	Portal protein
HI798_08080	COG2197	response regulator
HI798_08085	COG0840	transmembrane signaling receptor activity
HI798_08125	COG0747	negative chemotaxis
HI798_08145	COG0601	transmembrane transport
HI798_08150	COG2072	flavoprotein involved in K transport
HI798_08195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HI798_08205	COG0582	viral genome integration into host DNA
HI798_08240	COG0656	L-ascorbic acid biosynthetic process
HI798_08245	COG2304	oxidoreductase activity
HI798_08260	COG0589	response to stress
HI798_08295	COG0328	RNA-DNA hybrid ribonuclease activity
HI798_08300	COG2226	methyltransferase
HI798_08305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HI798_08310	COG1388	LysM domain
HI798_08310	COG0741	lytic transglycosylase activity
HI798_08315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HI798_08320	COG0505	Belongs to the CarA family
HI798_08330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HI798_08335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HI798_08345	COG1534	Rna-binding protein
HI798_08350	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HI798_08355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HI798_08360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HI798_08365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HI798_08370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HI798_08375	COG0573	inorganic phosphate transmembrane transporter activity
HI798_08380	COG0581	inorganic phosphate transmembrane transporter activity
HI798_08385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HI798_08395	COG0745	RESPONSE REGULATOR receiver
HI798_08405	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HI798_08410	COG0248	Ppx GppA phosphatase
HI798_08435	COG0730	response to heat
HI798_08445	COG0640	Transcriptional regulator
HI798_08455	COG3300	MHYT domain
HI798_08455	COG5001	Diguanylate cyclase
HI798_08495	COG3039	Transposase
HI798_08575	COG0277	FAD linked oxidase domain protein
HI798_08590	COG1295	ribonuclease BN
HI798_08615	COG0477	Major facilitator Superfamily
HI798_08620	COG0545	Peptidyl-prolyl cis-trans isomerase
HI798_08625	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HI798_08635	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_08640	COG4566	intracellular signal transduction
HI798_08655	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_08665	COG0251	oxidation-reduction process
HI798_08670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HI798_08680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HI798_08685	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HI798_08690	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HI798_08695	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HI798_08700	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HI798_08705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HI798_08705	COG0072	phenylalanine-tRNA ligase activity
HI798_08710	COG0776	regulation of translation
HI798_08740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HI798_08745	COG0531	amino acid
HI798_08765	COG1846	Transcriptional regulator
HI798_08775	COG0402	S-adenosylhomocysteine deaminase activity
HI798_08780	COG0339	signal peptide processing
HI798_08785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HI798_08790	COG4566	intracellular signal transduction
HI798_08805	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HI798_08810	COG0508	dehydrogenase complex catalyzes the overall conversion of
HI798_08820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HI798_08835	COG0123	including yeast histone deacetylase and acetoin utilization protein
HI798_08860	COG1414	Transcriptional regulator
HI798_08890	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HI798_08895	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HI798_08915	COG0167	dihydroorotate dehydrogenase activity
HI798_08925	COG3158	transport of potassium into the cell
HI798_08935	COG2183	response to ionizing radiation
HI798_08950	COG1199	ATP-dependent helicase activity
HI798_08960	COG0564	pseudouridine synthase activity
HI798_08975	COG3243	poly(R)-hydroxyalkanoic acid synthase
HI798_08980	COG0183	Belongs to the thiolase family
HI798_08985	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_08995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HI798_09000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HI798_09005	COG0183	Belongs to the thiolase family
HI798_09020	COG0560	Phosphoserine phosphatase
HI798_09030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HI798_09035	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HI798_09040	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HI798_09045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HI798_09050	COG0450	alkyl hydroperoxide reductase
HI798_09060	COG0745	RESPONSE REGULATOR receiver
HI798_09080	COG1562	ergosterol biosynthetic process
HI798_09085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI798_09100	COG0582	viral genome integration into host DNA
HI798_09125	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HI798_09220	COG3039	Transposase
HI798_09270	COG4386	tail sheath protein
HI798_09295	COG4228	DNA circulation
HI798_09300	COG3039	Transposase
HI798_09320	COG4381	Mu-like prophage protein gp46
HI798_09370	COG1652	LysM domain
HI798_09415	COG3039	Transposase
HI798_09480	COG1802	Transcriptional regulator
HI798_09480	COG4626	Terminase
HI798_09540	COG1196	nuclear chromosome segregation
HI798_09625	COG1652	LysM domain
HI798_09640	COG3039	Transposase
HI798_09660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI798_09660	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HI798_09665	COG0544	peptidyl-prolyl cis-trans isomerase activity
HI798_09670	COG0740	serine-type endopeptidase activity
HI798_09675	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HI798_09680	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HI798_09685	COG0776	regulation of translation
HI798_09700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI798_09720	COG4181	ATPase activity
HI798_09725	COG0166	Belongs to the GPI family
HI798_09730	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HI798_09740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HI798_09740	COG0047	phosphoribosylformylglycinamidine synthase activity
HI798_09765	COG0535	radical SAM domain protein
HI798_09795	COG0583	DNA-binding transcription factor activity
HI798_09800	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_09810	COG1176	ABC-type spermidine putrescine transport system, permease component I
HI798_09820	COG3842	ATPase activity
HI798_09825	COG0642	Histidine kinase
HI798_09835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_09840	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HI798_09865	COG1126	abc transporter atp-binding protein
HI798_09870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI798_09880	COG2917	probably involved in intracellular septation
HI798_09885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HI798_09890	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HI798_09895	COG0318	PFAM AMP-dependent synthetase and ligase
HI798_09905	COG0559	Belongs to the binding-protein-dependent transport system permease family
HI798_09935	COG0833	amino acid
HI798_09940	COG0833	amino acid
HI798_09950	COG1335	isochorismatase
HI798_09955	COG0183	Belongs to the thiolase family
HI798_09960	COG1960	acyl-CoA dehydrogenase activity
HI798_09965	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_09980	COG2130	NADP-dependent
HI798_10000	COG0596	Alpha beta hydrolase
HI798_10035	COG2831	hemolysin activation secretion protein
HI798_10055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HI798_10060	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HI798_10065	COG0470	DNA polymerase III
HI798_10075	COG0084	hydrolase, TatD family'
HI798_10085	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HI798_10090	COG1609	Transcriptional regulator
HI798_10095	COG1840	ABC-type Fe3 transport system, periplasmic component
HI798_10105	COG4208	sulfate ABC transporter
HI798_10110	COG3842	ATPase activity
HI798_10115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HI798_10120	COG3023	N-Acetylmuramoyl-L-alanine amidase
HI798_10155	COG0038	chloride channel
HI798_10160	COG2226	methyltransferase
HI798_10175	COG4771	TonB-dependent receptor
HI798_10195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HI798_10195	COG2226	methyltransferase
HI798_10195	COG3433	isochorismatase activity
HI798_10210	COG3039	Transposase
HI798_10220	COG0456	acetyltransferase
HI798_10260	COG0179	Fumarylacetoacetate (FAA) hydrolase
HI798_10305	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HI798_10330	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HI798_10345	COG2801	Transposase and inactivated derivatives
HI798_10415	COG2801	Transposase and inactivated derivatives
HI798_10440	COG2814	Major facilitator Superfamily
HI798_10465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI798_10475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HI798_10520	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HI798_10525	COG0156	8-amino-7-oxononanoate synthase activity
HI798_10560	COG3045	CreA protein
HI798_10600	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HI798_10615	COG0840	transmembrane signaling receptor activity
HI798_10625	COG3387	PFAM Glycoside hydrolase 15-related
HI798_10650	COG0488	(ABC) transporter
HI798_10655	COG1619	proteins homologs of microcin C7 resistance protein MccF
HI798_10665	COG0720	synthase
HI798_10670	COG0602	queuosine metabolic process
HI798_10690	COG3550	peptidyl-serine autophosphorylation
HI798_10710	COG3485	protocatechuate 3,4-dioxygenase
HI798_10715	COG3485	protocatechuate 3,4-dioxygenase
HI798_10720	COG0583	DNA-binding transcription factor activity
HI798_10765	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HI798_10765	COG0519	Catalyzes the synthesis of GMP from XMP
HI798_10780	COG0697	spore germination
HI798_10790	COG2914	Belongs to the UPF0125 (RnfH) family
HI798_10795	COG2867	negative regulation of translational initiation
HI798_10800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HI798_10805	COG0330	HflC and HflK could
HI798_10820	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HI798_10825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HI798_10830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HI798_10835	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HI798_10840	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HI798_10845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HI798_10850	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HI798_10865	COG0750	zinc metalloprotease
HI798_10870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HI798_10875	COG0575	Belongs to the CDS family
HI798_10880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HI798_10885	COG0233	cytoplasmic translational termination
HI798_10890	COG0528	UMP kinase activity
HI798_10895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HI798_10900	COG0052	Belongs to the universal ribosomal protein uS2 family
HI798_10905	COG0024	Methionine aminopeptidase
HI798_10910	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HI798_10915	COG1187	pseudouridine synthase activity
HI798_10925	COG0242	peptide deformylase activity
HI798_10930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HI798_10945	COG0596	Alpha beta hydrolase
HI798_10960	COG2171	N-acyltransferase activity
HI798_10970	COG1393	Belongs to the ArsC family
HI798_10975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HI798_10985	COG2890	protein-(glutamine-N5) methyltransferase activity
HI798_10990	COG0302	gtp cyclohydrolase
HI798_11015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HI798_11020	COG0601	transmembrane transport
HI798_11025	COG0747	negative chemotaxis
HI798_11030	COG4172	Belongs to the ABC transporter superfamily
HI798_11045	COG0488	(ABC) transporter
HI798_11055	COG1683	Conserved Protein
HI798_11060	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HI798_11070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HI798_11075	COG0477	Major facilitator Superfamily
HI798_11080	COG1573	uracil-dna glycosylase
HI798_11090	COG1214	PFAM Peptidase M22, glycoprotease
HI798_11100	COG2814	Major facilitator Superfamily
HI798_11110	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HI798_11120	COG0583	DNA-binding transcription factor activity
HI798_11130	COG2224	Isocitrate lyase
HI798_11150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HI798_11165	COG3275	phosphorelay sensor kinase activity
HI798_11180	COG0583	DNA-binding transcription factor activity
HI798_11185	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HI798_11190	COG4208	sulfate ABC transporter
HI798_11215	COG1116	anion transmembrane transporter activity
HI798_11220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HI798_11225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HI798_11230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HI798_11235	COG0431	NADPH-dependent FMN reductase
HI798_11240	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HI798_11245	COG2985	domain, Protein
HI798_11250	COG0281	malic enzyme
HI798_11265	COG4191	Histidine kinase
HI798_11275	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HI798_11285	COG0542	response to heat
HI798_11295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HI798_11300	COG0314	molybdopterin synthase activity
HI798_11305	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HI798_11310	COG0303	'Molybdopterin
HI798_11315	COG1573	uracil-dna glycosylase
HI798_11330	COG0436	Aminotransferase
HI798_11340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HI798_11345	COG2076	Multidrug Resistance protein
HI798_11350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HI798_11365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HI798_11365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HI798_11375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HI798_11380	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HI798_11390	COG0791	NLP P60 protein
HI798_11395	COG0306	phosphate transporter
HI798_11405	COG0305	Participates in initiation and elongation during chromosome replication
HI798_11410	COG0359	binds to the 23S rRNA
HI798_11415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HI798_11425	COG0360	Binds together with S18 to 16S ribosomal RNA
HI798_11440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HI798_11455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HI798_11480	COG1024	Enoyl-CoA hydratase
HI798_11505	COG1566	PFAM secretion protein HlyD family protein
HI798_11510	COG2814	Major facilitator Superfamily
HI798_11515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HI798_11520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HI798_11525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HI798_11530	COG2251	uridine kinase activity
HI798_11530	COG0195	Participates in both transcription termination and antitermination
HI798_11535	COG0779	Required for maturation of 30S ribosomal subunits
HI798_11540	COG1187	pseudouridine synthase activity
HI798_11545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HI798_11555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HI798_11590	COG3278	Belongs to the heme-copper respiratory oxidase family
HI798_11600	COG2217	Heavy metal translocating P-type atpase
HI798_11610	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HI798_11615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HI798_11620	COG0508	dehydrogenase complex catalyzes the overall conversion of
HI798_11625	COG0567	Dehydrogenase, E1 component
HI798_11630	COG0584	glycerophosphoryl diester phosphodiesterase
HI798_11635	COG3842	ATPase activity
HI798_11645	COG1175	transmembrane transport
HI798_11650	COG1653	transport
HI798_11665	COG2204	response regulator
HI798_11680	COG0174	glutamine synthetase
HI798_11690	COG1546	Belongs to the CinA family
HI798_11690	COG1058	Belongs to the CinA family
HI798_11715	COG1643	Atp-dependent helicase
HI798_11720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HI798_11720	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HI798_11725	COG1737	Transcriptional regulator
HI798_11730	COG0673	inositol 2-dehydrogenase activity
HI798_11740	COG0673	inositol 2-dehydrogenase activity
HI798_11750	COG1082	Xylose isomerase domain protein TIM barrel
HI798_11755	COG1172	Belongs to the binding-protein-dependent transport system permease family
HI798_11760	COG1129	ABC transporter
HI798_11770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HI798_11775	COG3962	Belongs to the TPP enzyme family
HI798_11785	COG3718	enzyme involved in inositol metabolism
HI798_11795	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HI798_11805	COG1953	Uracil, thiamine, allantoin
HI798_11810	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HI798_11815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HI798_11820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HI798_11825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HI798_11830	COG0557	exoribonuclease II activity
HI798_11840	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HI798_11845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HI798_11850	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HI798_11860	COG0330	HflC and HflK could
HI798_11865	COG0330	HflC and HflK could
HI798_11870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HI798_11875	COG1923	regulation of RNA biosynthetic process
HI798_11880	COG1160	GTP binding
HI798_11890	COG2976	Protein conserved in bacteria
HI798_11895	COG0124	histidyl-tRNA synthetase
HI798_11900	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HI798_11915	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HI798_11920	COG0105	UTP biosynthetic process
HI798_11930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HI798_11950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HI798_11955	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HI798_11960	COG0604	alcohol dehydrogenase
HI798_11960	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_11960	COG3321	synthase
HI798_11965	COG1902	pentaerythritol trinitrate reductase activity
HI798_11970	COG1309	transcriptional regulator
HI798_11975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HI798_11985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HI798_11990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HI798_12005	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HI798_12010	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HI798_12025	COG1074	ATP-dependent DNA helicase activity
HI798_12040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HI798_12045	COG2204	response regulator
HI798_12050	COG2197	response regulator
HI798_12055	COG3228	Belongs to the MtfA family
HI798_12065	COG0254	rRNA binding
HI798_12075	COG0534	Mate efflux family protein
HI798_12110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HI798_12115	COG1752	Esterase of the alpha-beta hydrolase superfamily
HI798_12120	COG0791	NLP P60 protein
HI798_12125	COG4172	Belongs to the ABC transporter superfamily
HI798_12130	COG4239	(ABC) transporter, permease
HI798_12135	COG4174	ABC transporter (Permease)
HI798_12140	COG4166	transmembrane transport
HI798_12155	COG0527	aspartate kinase activity
HI798_12160	COG0037	tRNA processing
HI798_12165	COG0825	malonyl-CoA metabolic process
HI798_12170	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HI798_12175	COG0215	cysteine-tRNA ligase activity
HI798_12190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HI798_12195	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HI798_12200	COG1045	serine acetyltransferase
HI798_12215	COG1396	sequence-specific DNA binding
HI798_12225	COG2258	MOSC domain
HI798_12235	COG0840	transmembrane signaling receptor activity
HI798_12245	COG2814	Major facilitator Superfamily
HI798_12250	COG0583	DNA-binding transcription factor activity
HI798_12285	COG4695	Portal protein
HI798_12515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HI798_12530	COG2850	peptidyl-arginine hydroxylation
HI798_12540	COG1234	tRNA 3'-trailer cleavage
HI798_12545	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HI798_12550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HI798_12560	COG0180	Tryptophanyl-tRNA synthetase
HI798_12565	COG1994	Peptidase M50
HI798_12570	COG0009	L-threonylcarbamoyladenylate synthase
HI798_12575	COG0613	PHP domain protein
HI798_12580	COG0492	ferredoxin-NADP+ reductase activity
HI798_12595	COG3011	Protein conserved in bacteria
HI798_12600	COG2267	carboxylic ester hydrolase activity
HI798_12605	COG2833	Protein of unknown function (DUF455)
HI798_12615	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HI798_12625	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HI798_12630	COG0148	phosphopyruvate hydratase activity
HI798_12640	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HI798_12645	COG0504	CTP synthase activity
HI798_12650	COG2267	carboxylic ester hydrolase activity
HI798_12670	COG2308	Evidence 4 Homologs of previously reported genes of
HI798_12680	COG0084	hydrolase, TatD family'
HI798_12685	COG1136	(ABC) transporter
HI798_12700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HI798_12705	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HI798_12730	COG2855	membrane
HI798_12735	COG0583	DNA-binding transcription factor activity
HI798_12775	COG0446	pyridine nucleotide-disulphide oxidoreductase
HI798_12775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HI798_12810	COG0436	Aminotransferase
HI798_12820	COG0583	DNA-binding transcription factor activity
HI798_12825	COG2271	Major facilitator Superfamily
HI798_12865	COG0625	glutathione transferase activity
HI798_12870	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_12880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_12890	COG2271	Major facilitator Superfamily
HI798_12900	COG2186	Transcriptional regulator
HI798_12905	COG3385	transposase activity
HI798_12915	COG0745	RESPONSE REGULATOR receiver
HI798_12920	COG5002	protein histidine kinase activity
HI798_12930	COG0745	RESPONSE REGULATOR receiver
HI798_12935	COG3772	lysozyme
HI798_12970	COG2176	DNA-directed DNA polymerase activity
HI798_12990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HI798_12990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HI798_13060	COG3039	Transposase
HI798_13065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HI798_13085	COG3039	Transposase
HI798_13190	COG3039	Transposase
HI798_13220	COG0322	excinuclease ABC activity
HI798_13230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HI798_13240	COG0736	holo-[acyl-carrier-protein] synthase activity
HI798_13245	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HI798_13250	COG1381	Involved in DNA repair and RecF pathway recombination
HI798_13255	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HI798_13260	COG0571	ribonuclease III activity
HI798_13270	COG0681	Belongs to the peptidase S26 family
HI798_13275	COG0481	GTPase activity
HI798_13285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HI798_13310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HI798_13315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HI798_13320	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_13330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HI798_13335	COG0416	fatty acid biosynthetic process
HI798_13340	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HI798_13345	COG1399	metal-binding, possibly nucleic acid-binding protein
HI798_13350	COG0424	maF-like protein
HI798_13360	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HI798_13360	COG0616	signal peptide processing
HI798_13370	COG0546	phosphoglycolate phosphatase activity
HI798_13380	COG1530	ribonuclease E activity
HI798_13385	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HI798_13390	COG0746	molybdenum cofactor guanylyltransferase activity
HI798_13405	COG1322	Protein conserved in bacteria
HI798_13410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HI798_13425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HI798_13435	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_13440	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HI798_13450	COG3385	transposase activity
HI798_13465	COG0443	Heat shock 70 kDa protein
HI798_13470	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HI798_13480	COG0316	Belongs to the HesB IscA family
HI798_13485	COG0822	iron-sulfur transferase activity
HI798_13490	COG1104	cysteine desulfurase activity
HI798_13500	COG1879	ABC-type sugar transport system periplasmic component
HI798_13510	COG1172	Belongs to the binding-protein-dependent transport system permease family
HI798_13515	COG1609	Transcriptional regulator
HI798_13520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HI798_13530	COG0556	nucleotide-excision repair
HI798_13545	COG1309	transcriptional regulator
HI798_13550	COG2878	Part of a membrane complex involved in electron transport
HI798_13555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HI798_13560	COG0778	Nitroreductase
HI798_13595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HI798_13635	COG0326	Molecular chaperone. Has ATPase activity
HI798_13640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI798_13645	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HI798_13650	COG0697	spore germination
HI798_13660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI798_13665	COG0625	glutathione transferase activity
HI798_13680	COG1620	l-lactate permease
HI798_13700	COG0741	lytic transglycosylase activity
HI798_13750	COG0513	Belongs to the DEAD box helicase family
HI798_13755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HI798_13765	COG0861	Integral membrane protein TerC family
HI798_13775	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HI798_13785	COG0312	modulator of DNA gyrase
HI798_13790	COG3028	Belongs to the UPF0307 family
HI798_13795	COG0521	Mo-molybdopterin cofactor biosynthetic process
HI798_13800	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HI798_13805	COG0501	Belongs to the peptidase M48B family
HI798_13810	COG1162	GTPase activity
HI798_13820	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HI798_13825	COG0494	nUDIX hydrolase
HI798_13830	COG0335	large ribosomal subunit rRNA binding
HI798_13835	COG0336	Belongs to the RNA methyltransferase TrmD family
HI798_13840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HI798_13845	COG0228	four-way junction DNA binding
HI798_13880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI798_13885	COG1960	acyl-CoA dehydrogenase activity
HI798_13905	COG2011	ABC-type metal ion transport system permease component
HI798_13910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HI798_13915	COG0123	including yeast histone deacetylase and acetoin utilization protein
HI798_13920	COG2951	lytic endotransglycosylase activity
HI798_13935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HI798_13940	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HI798_13950	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HI798_13960	COG0776	regulation of translation
HI798_13970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HI798_13975	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HI798_13980	COG0287	Prephenate dehydrogenase
HI798_13985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HI798_13990	COG0077	Prephenate dehydratase
HI798_13990	COG1605	Chorismate mutase
HI798_13995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HI798_14020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HI798_14100	COG3501	Rhs element vgr protein
HI798_14105	COG0583	DNA-binding transcription factor activity
HI798_14210	COG2916	Histone family protein nucleoid-structuring protein H-NS
HI798_14335	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HI798_14500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI798_14510	COG3210	domain, Protein
HI798_14535	COG3039	Transposase
HI798_14605	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HI798_14640	COG4221	oxidoreductase activity
HI798_14765	COG1309	transcriptional regulator
HI798_14775	COG0604	alcohol dehydrogenase
HI798_14800	COG0778	Nitroreductase
HI798_14815	COG4305	rare lipoprotein A
HI798_14840	COG1280	lysine exporter protein (LysE YggA)
HI798_14855	COG0425	Belongs to the sulfur carrier protein TusA family
HI798_14870	COG1942	4-Oxalocrotonate Tautomerase
HI798_14875	COG0235	Class ii aldolase
HI798_14880	COG0477	Major facilitator Superfamily
HI798_14895	COG0330	HflC and HflK could
HI798_14920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HI798_14925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HI798_14950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HI798_14980	COG4681	YaeQ
HI798_14995	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HI798_15005	COG0318	PFAM AMP-dependent synthetase and ligase
HI798_15010	COG3118	belongs to the thioredoxin family
HI798_15020	COG2703	oxygen carrier activity
HI798_15025	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HI798_15030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HI798_15035	COG2982	Protein involved in outer membrane biogenesis
HI798_15060	COG0259	pyridoxamine-phosphate oxidase activity
HI798_15065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HI798_15075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HI798_15080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HI798_15090	COG1522	sequence-specific DNA binding
HI798_15095	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HI798_15105	COG3483	tryptophan 2,3-dioxygenase activity
HI798_15115	COG1960	acyl-CoA dehydrogenase activity
HI798_15120	COG2252	PERMEase
HI798_15125	COG0450	alkyl hydroperoxide reductase
HI798_15130	COG4575	ribosome binding
HI798_15150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HI798_15155	COG0390	transport system, permease component
HI798_15180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HI798_15185	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HI798_15190	COG0745	RESPONSE REGULATOR receiver
HI798_15200	COG3385	transposase activity
HI798_15210	COG2391	methyltransferase activity
HI798_15215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HI798_15230	COG0823	Involved in the tonB-independent uptake of proteins
HI798_15250	COG0824	Thioesterase
HI798_15255	COG4221	oxidoreductase activity
HI798_15260	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HI798_15265	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HI798_15330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HI798_15330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HI798_15345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HI798_15350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HI798_15365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HI798_15395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HI798_15400	COG1902	pentaerythritol trinitrate reductase activity
HI798_15405	COG1968	undecaprenyl-diphosphatase activity
HI798_15425	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HI798_15430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HI798_15430	COG0425	Belongs to the sulfur carrier protein TusA family
HI798_15450	COG0859	PFAM glycosyl transferase family 9
HI798_15465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HI798_15500	COG1088	dTDP-glucose 4,6-dehydratase activity
HI798_15505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HI798_15520	COG0540	Belongs to the ATCase OTCase family
HI798_15525	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HI798_15530	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HI798_15535	COG1678	Uncharacterized ACR, COG1678
HI798_15540	COG1187	pseudouridine synthase activity
HI798_15550	COG2198	Histidine kinase
HI798_15550	COG0784	Response regulator, receiver
HI798_15550	COG0643	Histidine kinase
HI798_15555	COG0840	transmembrane signaling receptor activity
HI798_15575	COG1773	rubredoxin
HI798_15580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HI798_15585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HI798_15590	COG1704	LemA family
HI798_15635	COG4964	Belongs to the GSP D family
HI798_15695	COG4269	membrane
HI798_15700	COG0459	protein refolding
HI798_15705	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HI798_15720	COG0443	Heat shock 70 kDa protein
HI798_15730	COG0604	alcohol dehydrogenase
HI798_15735	COG1309	transcriptional regulator
HI798_15745	COG0583	DNA-binding transcription factor activity
HI798_15755	COG1064	alcohol dehydrogenase
HI798_15770	COG4654	Cytochrome c, class I
HI798_15790	COG2207	Transcriptional regulator
HI798_15810	COG0513	Belongs to the DEAD box helicase family
HI798_15815	COG0583	DNA-binding transcription factor activity
HI798_15820	COG0656	L-ascorbic acid biosynthetic process
HI798_15840	COG1073	alpha beta
HI798_15845	COG2974	May be involved in recombination
HI798_15910	COG0840	transmembrane signaling receptor activity
HI798_15915	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HI798_15935	COG2995	paraquat-inducible protein a
HI798_15940	COG3008	intermembrane lipid transfer
HI798_15940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HI798_15950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI798_16020	COG0738	Major facilitator superfamily
HI798_16025	COG2027	D-alanyl-D-alanine carboxypeptidase
HI798_16030	COG1763	Mo-molybdopterin cofactor biosynthetic process
HI798_16040	COG0546	phosphoglycolate phosphatase activity
HI798_16050	COG0009	L-threonylcarbamoyladenylate synthase
HI798_16055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HI798_16060	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HI798_16065	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HI798_16075	COG0469	pyruvate kinase activity
HI798_16080	COG0126	phosphoglycerate kinase activity
HI798_16110	COG0859	PFAM glycosyl transferase family 9
HI798_16120	COG0429	hydrolase of the alpha beta-hydrolase fold
HI798_16130	COG4783	chaperone-mediated protein folding
HI798_16135	COG0315	cyclic pyranopterin monophosphate synthase activity
HI798_16145	COG4969	Belongs to the N-Me-Phe pilin family
HI798_16155	COG0861	Integral membrane protein TerC family
HI798_16165	COG0045	succinate-CoA ligase (ADP-forming) activity
HI798_16175	COG2137	regulation of response to DNA damage stimulus
HI798_16180	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HI798_16190	COG0642	Histidine kinase
HI798_16200	COG0477	Major facilitator Superfamily
HI798_16245	COG0513	Belongs to the DEAD box helicase family
HI798_16270	COG0318	PFAM AMP-dependent synthetase and ligase
HI798_16295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HI798_16300	COG1702	phosphate starvation-inducible protein PhoH
HI798_16305	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HI798_16310	COG4535	Mg2 and Co2 transporter CorC
HI798_16315	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HI798_16320	COG0752	glycyl-tRNA synthetase alpha subunit
HI798_16330	COG0751	glycine-tRNA ligase activity
HI798_16335	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HI798_16340	COG0204	Acyl-transferase
HI798_16350	COG0346	lactoylglutathione lyase activity
HI798_16355	COG0697	spore germination
HI798_16360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HI798_16365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HI798_16370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI798_16375	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HI798_16395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HI798_16405	COG0006	proline dipeptidase activity
HI798_16410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HI798_16435	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HI798_16440	COG0138	bifunctional purine biosynthesis protein purh
HI798_16445	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HI798_16455	COG0632	four-way junction helicase activity
HI798_16460	COG2255	four-way junction helicase activity
HI798_16475	COG1490	D-aminoacyl-tRNA deacylase activity
HI798_16480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HI798_16485	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HI798_16490	COG0316	Belongs to the HesB IscA family
HI798_16505	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HI798_16510	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HI798_16530	COG0418	dihydroorotase activity
HI798_16540	COG0473	3-isopropylmalate dehydrogenase activity
HI798_16545	COG0121	glutamine amidotransferase
HI798_16550	COG1126	abc transporter atp-binding protein
HI798_16555	COG0765	amino acid transport
HI798_16560	COG0765	amino acid transport
HI798_16570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HI798_16580	COG5265	(ABC) transporter
HI798_16590	COG1024	Enoyl-CoA hydratase
HI798_16595	COG0183	Belongs to the thiolase family
HI798_16600	COG1250	3-hydroxyacyl-CoA dehydrogenase
HI798_16600	COG1024	Enoyl-CoA hydratase
HI798_16605	COG1960	acyl-CoA dehydrogenase activity
HI798_16620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HI798_16625	COG3568	Endonuclease Exonuclease Phosphatase
HI798_16630	COG0494	nUDIX hydrolase
HI798_16640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HI798_16665	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HI798_16680	COG2226	methyltransferase
HI798_16690	COG4178	(ABC) transporter
HI798_16705	COG1238	metal cluster binding
HI798_16710	COG0700	Nucleoside recognition
HI798_16725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HI798_16730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HI798_16730	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HI798_16760	COG0318	PFAM AMP-dependent synthetase and ligase
HI798_16765	COG3265	gluconokinase activity
HI798_16780	COG2391	methyltransferase activity
HI798_16795	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_16810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HI798_16835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HI798_16870	COG0629	single-stranded DNA binding
HI798_16875	COG2814	Major facilitator Superfamily
HI798_16890	COG1280	lysine exporter protein (LysE YggA)
HI798_16895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HI798_16900	COG0693	protein deglycase activity
HI798_16920	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HI798_16935	COG1137	ATPase activity
HI798_16940	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HI798_16945	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HI798_16955	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HI798_16965	COG1660	Displays ATPase and GTPase activities
HI798_16975	COG1194	a g-specific adenine glycosylase
HI798_16985	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HI798_16995	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HI798_17000	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HI798_17010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HI798_17015	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HI798_17020	COG0193	aminoacyl-tRNA hydrolase activity
HI798_17030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HI798_17035	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HI798_17040	COG0742	ribosomal rna small subunit methyltransferase
HI798_17045	COG0612	Peptidase, M16
HI798_17050	COG0612	Peptidase, M16
HI798_17065	COG0625	glutathione transferase activity
HI798_17075	COG3707	response regulator
HI798_17080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HI798_17085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HI798_17090	COG1116	anion transmembrane transporter activity
HI798_17095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HI798_17100	COG1741	Belongs to the pirin family
HI798_17110	COG5001	Diguanylate cyclase
HI798_17110	COG3300	MHYT domain
HI798_17115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HI798_17120	COG1999	signal sequence binding
HI798_17125	COG0109	protoheme IX farnesyltransferase activity
HI798_17130	COG1612	heme a metabolic process
HI798_17160	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HI798_17165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HI798_17180	COG2226	methyltransferase
HI798_17185	COG1040	competence protein
HI798_17195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HI798_17200	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HI798_17205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HI798_17210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HI798_17215	COG0588	phosphoglycerate mutase activity
HI798_17220	COG0793	Belongs to the peptidase S41A family
HI798_17240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HI798_17245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HI798_17255	COG0189	ligase activity
HI798_17265	COG0004	ammonium transporteR
HI798_17290	COG0606	chelatase, subunit chli
HI798_17310	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HI798_17320	COG2204	response regulator
HI798_17325	COG4191	Histidine kinase
HI798_17330	COG1301	dicarboxylic acid transport
HI798_17335	COG3411	Ferredoxin
HI798_17345	COG1686	Belongs to the peptidase S11 family
HI798_17350	COG2921	Belongs to the UPF0250 family
HI798_17355	COG0583	DNA-binding transcription factor activity
HI798_17365	COG0321	lipoyl(octanoyl) transferase activity
HI798_17370	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HI798_17385	COG3511	phospholipase C
HI798_17415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HI798_17420	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HI798_17420	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HI798_17425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HI798_17435	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HI798_17460	COG1024	Enoyl-CoA hydratase
HI798_17490	COG2267	carboxylic ester hydrolase activity
HI798_17510	COG1410	methionine synthase
HI798_17510	COG0646	methionine synthase
HI798_17520	COG2197	response regulator
HI798_17550	COG0018	arginyl-trna synthetase
HI798_17560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HI798_17565	COG4221	oxidoreductase activity
HI798_17575	COG3039	Transposase
HI798_17605	COG2329	Antibiotic biosynthesis monooxygenase
HI798_17615	COG0789	Transcriptional regulator
HI798_17620	COG1960	acyl-CoA dehydrogenase activity
HI798_17625	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HI798_17630	COG0288	reversible hydration of carbon dioxide
HI798_17635	COG0183	Belongs to the thiolase family
HI798_17640	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_17645	COG1960	acyl-CoA dehydrogenase activity
HI798_17660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HI798_17665	COG3012	SEC-C Motif Domain Protein
HI798_17670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HI798_17680	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HI798_17685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HI798_17690	COG4770	biotin carboxylase activity
HI798_17705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HI798_17735	COG0596	Alpha beta hydrolase
HI798_17765	COG3039	Transposase
HI798_17775	COG3039	Transposase
HI798_17785	COG1250	3-hydroxyacyl-CoA dehydrogenase
HI798_17790	COG0583	DNA-binding transcription factor activity
HI798_17820	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HI798_17820	COG1703	isobutyryl-CoA mutase activity
HI798_17820	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HI798_17860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HI798_17870	COG0430	RNA-3'-phosphate cyclase activity
HI798_17875	COG3541	Predicted nucleotidyltransferase
HI798_17880	COG1690	Belongs to the RtcB family
HI798_17890	COG4650	regulator
HI798_17905	COG1254	Belongs to the acylphosphatase family
HI798_17920	COG2814	Major facilitator Superfamily
HI798_17925	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_17930	COG0583	DNA-binding transcription factor activity
HI798_17935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HI798_17935	COG0519	Catalyzes the synthesis of GMP from XMP
HI798_17950	COG1733	regulation of RNA biosynthetic process
HI798_17985	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HI798_17995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HI798_18000	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HI798_18005	COG0071	Belongs to the small heat shock protein (HSP20) family
HI798_18015	COG3038	cytochrome b561
HI798_18035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HI798_18045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HI798_18045	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HI798_18050	COG1063	alcohol dehydrogenase
HI798_18060	COG2197	response regulator
HI798_18065	COG3851	Histidine kinase
HI798_18070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HI798_18100	COG0589	response to stress
HI798_18105	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HI798_18125	COG0589	response to stress
HI798_18130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HI798_18135	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HI798_18145	COG0037	tRNA processing
HI798_18150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HI798_18155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HI798_18155	COG0546	phosphoglycolate phosphatase activity
HI798_18180	COG0493	'glutamate synthase
HI798_18195	COG0842	Transport permease protein
HI798_18200	COG1131	(ABC) transporter
HI798_18215	COG1012	belongs to the aldehyde dehydrogenase family
HI798_18220	COG0583	DNA-binding transcription factor activity
HI798_18225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HI798_18250	COG2223	nitrite transmembrane transporter activity
HI798_18265	COG0697	spore germination
HI798_18290	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HI798_18315	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HI798_18320	COG4682	membrane
HI798_18325	COG0708	Exodeoxyribonuclease III
HI798_18330	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HI798_18335	COG2326	polyphosphate kinase activity
HI798_18340	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HI798_18345	COG1560	Kdo2-lipid A biosynthetic process
HI798_18355	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HI798_18385	COG0517	IMP dehydrogenase activity
HI798_18395	COG1522	sequence-specific DNA binding
HI798_18440	COG1960	acyl-CoA dehydrogenase activity
HI798_18475	COG2070	2-Nitropropane dioxygenase
HI798_18480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HI798_18495	COG2022	thiamine diphosphate biosynthetic process
HI798_18505	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HI798_18530	COG0351	phosphomethylpyrimidine kinase
HI798_18540	COG1785	Belongs to the alkaline phosphatase family
HI798_18545	COG1785	Belongs to the alkaline phosphatase family
HI798_18560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HI798_18565	COG1950	PFAM Membrane protein of
HI798_18570	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HI798_18580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HI798_18600	COG0617	tRNA 3'-terminal CCA addition
HI798_18610	COG3246	L-lysine catabolic process to acetate
HI798_18615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HI798_18640	COG2204	response regulator
HI798_18645	COG5000	phosphorelay sensor kinase activity
HI798_18660	COG0501	Belongs to the peptidase M48B family
HI798_18670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HI798_18680	COG0242	peptide deformylase activity
HI798_18685	COG1652	LysM domain
HI798_18690	COG0758	DNA mediated transformation
HI798_18705	COG0583	DNA-binding transcription factor activity
HI798_18710	COG0318	PFAM AMP-dependent synthetase and ligase
HI798_18715	COG0772	Belongs to the SEDS family
HI798_18720	COG0768	penicillin binding
HI798_18730	COG1792	Involved in formation and maintenance of cell shape
HI798_18735	COG1077	Cell shape determining protein MreB Mrl
HI798_18740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HI798_18745	COG0154	amidase activity
HI798_18760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HI798_18770	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HI798_18775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HI798_18795	COG0523	cobalamin synthesis protein
HI798_18810	COG0747	negative chemotaxis
HI798_18815	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HI798_18820	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HI798_18830	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HI798_18860	COG1595	DNA-templated transcription, initiation
HI798_18865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HI798_18885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HI798_18895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HI798_18905	COG3385	transposase activity
HI798_18920	COG2879	small protein
HI798_18925	COG1966	Carbon starvation protein
HI798_18940	COG3622	Belongs to the hyi family
HI798_18950	COG0745	RESPONSE REGULATOR receiver
HI798_18955	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HI798_18960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HI798_18965	COG3384	dioxygenase
HI798_18980	COG1309	transcriptional regulator
HI798_18985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI798_18990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HI798_19000	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HI798_19015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HI798_19020	COG0706	membrane insertase activity
HI798_19025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HI798_19030	COG0594	ribonuclease P activity
HI798_19035	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HI798_19045	COG1278	Cold shock
HI798_19070	COG0477	Major facilitator Superfamily
HI798_19075	COG4191	Histidine kinase
HI798_19085	COG4377	Putative membrane peptidase family (DUF2324)
HI798_19095	COG5002	protein histidine kinase activity
HI798_19095	COG5001	Diguanylate cyclase
HI798_19095	COG3447	MASE1 domain protein
HI798_19135	COG0038	chloride channel
HI798_19155	COG1881	PFAM PEBP family protein
HI798_19230	COG0582	viral genome integration into host DNA
HI798_19245	COG2916	Histone family protein nucleoid-structuring protein H-NS
HI798_19265	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_19275	COG1024	Enoyl-CoA hydratase
HI798_19280	COG1960	acyl-CoA dehydrogenase activity
HI798_19320	COG3039	Transposase
HI798_19335	COG0477	Major facilitator Superfamily
HI798_19340	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HI798_19345	COG3657	addiction module killer protein
HI798_19350	COG2814	Major facilitator Superfamily
HI798_19385	COG0725	ABC transporter, periplasmic molybdate-binding protein
HI798_19400	COG0714	Associated with various cellular activities
HI798_19415	COG0288	reversible hydration of carbon dioxide
HI798_19465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HI798_19475	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HI798_19480	COG2944	sequence-specific DNA binding
HI798_19490	COG3039	Transposase
HI798_19505	COG3039	Transposase
HI798_19520	COG0697	spore germination
HI798_19535	COG1902	pentaerythritol trinitrate reductase activity
HI798_19535	COG0446	pyridine nucleotide-disulphide oxidoreductase
HI798_19545	COG4677	pectinesterase activity
HI798_19560	COG4968	Prepilin-type N-terminal cleavage methylation domain
HI798_19570	COG4796	Type ii and iii secretion system protein
HI798_19595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HI798_19635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HI798_19645	COG0534	Mate efflux family protein
HI798_19650	COG3251	PFAM MbtH domain protein
HI798_19660	COG0529	Catalyzes the synthesis of activated sulfate
HI798_19690	COG3039	Transposase
HI798_19700	COG1104	cysteine desulfurase activity
HI798_19755	COG2706	6-phosphogluconolactonase activity
HI798_19785	COG0730	response to heat
HI798_19825	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HI798_19835	COG0028	Belongs to the TPP enzyme family
HI798_19850	COG1607	acyl-coa hydrolase
HI798_19865	COG3039	Transposase
HI798_19900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HI798_19930	COG3039	Transposase
HI798_19970	COG1846	Transcriptional regulator
HI798_19975	COG1024	Enoyl-CoA hydratase
HI798_19980	COG1012	belongs to the aldehyde dehydrogenase family
HI798_20020	COG2814	Major facilitator Superfamily
HI798_20030	COG1640	4-alpha-glucanotransferase
HI798_20035	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HI798_20045	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HI798_20050	COG0366	Alpha amylase catalytic
HI798_20055	COG0366	Alpha amylase catalytic
HI798_20060	COG0297	glycogen (starch) synthase activity
HI798_20065	COG3720	iron ion transport
HI798_20070	COG4771	TonB-dependent receptor
HI798_20080	COG3634	alkyl hydroperoxide reductase activity
HI798_20085	COG0735	belongs to the Fur family
HI798_20105	COG1918	ferrous iron import across plasma membrane
HI798_20105	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HI798_20115	COG5002	protein histidine kinase activity
HI798_20115	COG5001	Diguanylate cyclase
HI798_20115	COG3447	MASE1 domain protein
HI798_20125	COG0840	transmembrane signaling receptor activity
HI798_20145	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HI798_20160	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HI798_20170	COG0456	acetyltransferase
HI798_20170	COG0454	-acetyltransferase
HI798_20235	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HI798_20250	COG3706	GGDEF domain
HI798_20255	COG0531	amino acid
HI798_20260	COG0534	Mate efflux family protein
HI798_20270	COG2197	response regulator
HI798_20280	COG1649	PFAM Uncharacterised BCR, COG1649
HI798_20280	COG0726	polysaccharide deacetylase
HI798_20285	COG1215	transferase activity, transferring glycosyl groups
HI798_20300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI798_20305	COG2274	protein secretion by the type I secretion system
HI798_20340	COG0840	transmembrane signaling receptor activity
HI798_20350	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_20360	COG2070	2-Nitropropane dioxygenase
HI798_20365	COG0583	DNA-binding transcription factor activity
HI798_20370	COG1695	Transcriptional regulator
HI798_20385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HI798_20390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI798_20395	COG0745	RESPONSE REGULATOR receiver
HI798_20400	COG2205	protein histidine kinase activity
HI798_20415	COG0589	response to stress
HI798_20440	COG0789	Transcriptional regulator
HI798_20450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HI798_20470	COG1764	response to oxidative stress
HI798_20485	COG0473	3-isopropylmalate dehydrogenase activity
HI798_20515	COG2916	Histone family protein nucleoid-structuring protein H-NS
HI798_20520	COG2188	Transcriptional regulator
HI798_20525	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_20530	COG2197	response regulator
HI798_20550	COG1815	bacterial-type flagellum-dependent cell motility
HI798_20560	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HI798_20565	COG1749	Flagellar hook protein flgE
HI798_20570	COG4787	bacterial-type flagellum-dependent cell motility
HI798_20580	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HI798_20585	COG1706	bacterial-type flagellum-dependent cell motility
HI798_20595	COG1256	bacterial-type flagellum assembly
HI798_20615	COG2226	methyltransferase
HI798_20630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HI798_20635	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_20645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HI798_20665	COG2986	histidine ammonia-lyase
HI798_20675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HI798_20685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HI798_20695	COG0204	Acyl-transferase
HI798_20710	COG1987	bacterial-type flagellum assembly
HI798_20715	COG1338	Plays a role in the flagellum-specific transport system
HI798_20745	COG2197	response regulator
HI798_20770	COG1846	Transcriptional regulator
HI798_20785	COG1677	Flagellar hook-basal body complex protein FliE
HI798_20795	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HI798_20830	COG5001	Diguanylate cyclase
HI798_20830	COG3706	GGDEF domain
HI798_20830	COG4251	negative regulation of phosphorylation
HI798_20830	COG2203	Gaf domain
HI798_20840	COG4251	negative regulation of phosphorylation
HI798_20840	COG2203	Gaf domain
HI798_20840	COG3706	GGDEF domain
HI798_20840	COG5001	Diguanylate cyclase
HI798_20865	COG3039	Transposase
HI798_20875	COG3385	transposase activity
HI798_20895	COG0318	PFAM AMP-dependent synthetase and ligase
HI798_20945	COG4774	siderophore transport
HI798_20965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HI798_20970	COG2423	ornithine cyclodeaminase activity
HI798_20975	COG4264	IucA IucC family
HI798_20980	COG2814	Major facilitator Superfamily
HI798_20985	COG4264	IucA IucC family
HI798_20990	COG4264	IucA IucC family
HI798_21000	COG0019	diaminopimelate decarboxylase activity
HI798_21045	COG1902	pentaerythritol trinitrate reductase activity
HI798_21055	COG0583	DNA-binding transcription factor activity
HI798_21060	COG1126	abc transporter atp-binding protein
HI798_21070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HI798_21075	COG1522	sequence-specific DNA binding
HI798_21080	COG2423	ornithine cyclodeaminase activity
HI798_21100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HI798_21135	COG0537	adenosine 5'-monophosphoramidase activity
HI798_21170	COG3039	Transposase
HI798_21185	COG3039	Transposase
HI798_21190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HI798_21200	COG0840	transmembrane signaling receptor activity
HI798_21215	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HI798_21235	COG0668	transmembrane transport
HI798_21270	COG3501	Rhs element vgr protein
HI798_21275	COG3706	GGDEF domain
HI798_21280	COG1914	H( )-stimulated, divalent metal cation uptake system
HI798_21305	COG2910	NAD(P)H-binding
HI798_21355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HI798_21395	COG3039	Transposase
HI798_21425	COG0402	S-adenosylhomocysteine deaminase activity
HI798_21480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HI798_21490	COG3621	Patatin-like phospholipase
HI798_21590	COG4942	peptidase
HI798_21610	COG3210	domain, Protein
HI798_21630	COG3210	domain, Protein
HI798_21640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI798_21665	COG1113	amino acid transport
HI798_21740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HI798_21765	COG3501	Rhs element vgr protein
HI798_21835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HI798_21860	COG3039	Transposase
HI798_21910	COG3039	Transposase
HI798_21945	COG3039	Transposase
HI798_21950	COG3039	Transposase
HI798_21990	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HI798_22015	COG0683	leucine binding
HI798_22040	COG3766	membrane
HI798_22060	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HI798_22090	COG4968	Prepilin-type N-terminal cleavage methylation domain
HI798_22095	COG1609	Transcriptional regulator
HI798_22105	COG1621	beta-fructofuranosidase activity
HI798_22135	COG0114	fumarate hydratase activity
HI798_22140	COG0477	Major facilitator Superfamily
HI798_22160	COG1742	UPF0060 membrane protein
HI798_22165	COG0668	transmembrane transport
HI798_22195	COG0730	response to heat
HI798_22210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HI798_22215	COG0730	response to heat
HI798_22220	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HI798_22245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HI798_22300	COG0251	oxidation-reduction process
HI798_22310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HI798_22315	COG1294	oxidase, subunit
HI798_22320	COG1271	oxidase subunit
HI798_22330	COG2951	lytic endotransglycosylase activity
HI798_22345	COG3039	Transposase
HI798_22350	COG5297	Belongs to the glycosyl hydrolase family 6
HI798_22370	COG0300	oxidoreductase activity
HI798_22400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HI798_22410	COG0835	chemotaxis
HI798_22410	COG0784	Response regulator, receiver
HI798_22435	COG1404	Belongs to the peptidase S8 family
HI798_22440	COG3396	Phenylacetate-CoA oxygenase
HI798_22445	COG3460	Phenylacetate-CoA oxygenase
HI798_22450	COG3396	Phenylacetate-CoA oxygenase
HI798_22455	COG2151	metal-sulfur cluster biosynthetic enzyme
HI798_22460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HI798_22495	COG0778	Nitroreductase
HI798_22500	COG1797	cobyrinic acid a,c-diamide synthase activity
HI798_22535	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HI798_22540	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HI798_22545	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HI798_22545	COG1648	precorrin-2 dehydrogenase activity
HI798_22560	COG3411	Ferredoxin
HI798_22565	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HI798_22600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HI798_22605	COG4941	Belongs to the sigma-70 factor family
HI798_22620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HI798_22625	COG3251	PFAM MbtH domain protein
HI798_22645	COG1522	sequence-specific DNA binding
HI798_22650	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HI798_22655	COG1024	Enoyl-CoA hydratase
HI798_22660	COG1024	Enoyl-CoA hydratase
HI798_22675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HI798_22680	COG1960	acyl-CoA dehydrogenase activity
HI798_22695	COG5002	protein histidine kinase activity
HI798_22700	COG0745	RESPONSE REGULATOR receiver
HI798_22725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_22735	COG1846	Transcriptional regulator
HI798_22750	COG1335	isochorismatase
HI798_22760	COG2814	Major facilitator Superfamily
HI798_22775	COG2818	Glycosylase
HI798_22780	COG2807	transmembrane transport
HI798_22805	COG1024	Enoyl-CoA hydratase
HI798_22830	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HI798_22835	COG0583	DNA-binding transcription factor activity
HI798_22840	COG0259	pyridoxamine-phosphate oxidase activity
HI798_22865	COG0134	indole-3-glycerol-phosphate synthase activity
HI798_22870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HI798_22900	COG1960	acyl-CoA dehydrogenase activity
HI798_22920	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HI798_22935	COG3483	tryptophan 2,3-dioxygenase activity
HI798_22960	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HI798_22965	COG1690	Belongs to the RtcB family
HI798_23010	COG3039	Transposase
HI798_23060	COG1858	cytochrome C peroxidase
HI798_23065	COG1730	sister chromatid segregation
HI798_23085	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HI798_23120	COG1454	alcohol dehydrogenase
HI798_23125	COG0477	Major facilitator Superfamily
HI798_23130	COG0352	thiamine-phosphate diphosphorylase activity
HI798_23150	COG2197	response regulator
HI798_23155	COG3850	Histidine kinase
HI798_23160	COG1763	Mo-molybdopterin cofactor biosynthetic process
HI798_23165	COG2181	nitrate reductase activity
HI798_23170	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HI798_23175	COG1140	nitrate reductase beta subunit
HI798_23180	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HI798_23185	COG2223	nitrite transmembrane transporter activity
HI798_23200	COG0826	peptidase U32
HI798_23205	COG0826	peptidase U32
HI798_23210	COG3154	lipid carrier protein
HI798_23240	COG1396	sequence-specific DNA binding
HI798_23250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HI798_23255	COG3604	Transcriptional regulator
HI798_23260	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
HI798_23300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_23320	COG1063	alcohol dehydrogenase
HI798_23325	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_23330	COG3265	gluconokinase activity
HI798_23340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HI798_23345	COG0436	Aminotransferase
HI798_23355	COG0511	ligase activity, forming carbon-carbon bonds
HI798_23365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HI798_23370	COG1984	allophanate hydrolase subunit 2
HI798_23380	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HI798_23385	COG4221	oxidoreductase activity
HI798_23390	COG0765	amino acid transport
HI798_23395	COG0765	amino acid transport
HI798_23400	COG1126	abc transporter atp-binding protein
HI798_23405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HI798_23425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI798_23450	COG2801	Transposase and inactivated derivatives
HI798_23460	COG0745	RESPONSE REGULATOR receiver
HI798_23465	COG2853	Lipoprotein
HI798_23475	COG3039	Transposase
HI798_23490	COG2801	Transposase and inactivated derivatives
HI798_23500	COG2801	Transposase and inactivated derivatives
HI798_23525	COG1309	transcriptional regulator
HI798_23540	COG0583	DNA-binding transcription factor activity
HI798_23545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HI798_23575	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HI798_23595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HI798_23605	COG2271	Major facilitator Superfamily
HI798_23610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HI798_23615	COG4569	acetaldehyde dehydrogenase (acetylating) activity
HI798_23620	COG1942	4-Oxalocrotonate Tautomerase
HI798_23665	COG1674	ftsk spoiiie
HI798_23685	COG5434	Belongs to the glycosyl hydrolase 28 family
HI798_23715	COG1450	Type ii and iii secretion system protein
HI798_23720	COG2207	Transcriptional regulator
HI798_23765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HI798_23770	COG4789	Type iii secretion
HI798_23785	COG4790	Type iii secretion
HI798_23825	COG0745	RESPONSE REGULATOR receiver
HI798_23830	COG2197	response regulator
HI798_23840	COG1595	DNA-templated transcription, initiation
HI798_23890	COG0840	transmembrane signaling receptor activity
HI798_23915	COG1056	cytidyltransferase-related domain
HI798_23915	COG1051	belongs to the nudix hydrolase family
HI798_23920	COG2271	Major facilitator Superfamily
HI798_23935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HI798_23940	COG2721	sulfolactate sulfo-lyase activity
HI798_23950	COG2271	Major facilitator Superfamily
HI798_23960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HI798_23965	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HI798_23975	COG0583	DNA-binding transcription factor activity
HI798_24000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HI798_24010	COG1309	transcriptional regulator
HI798_24020	COG0579	oxidoreductase
HI798_24035	COG4206	TonB-dependent receptor
HI798_24040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HI798_24055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HI798_24070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HI798_24080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HI798_24085	COG3620	sequence-specific DNA binding
HI798_24090	COG0587	DNA-directed DNA polymerase activity
HI798_24105	COG2814	Major facilitator Superfamily
HI798_24120	COG0436	Aminotransferase
HI798_24135	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_24135	COG3321	synthase
HI798_24135	COG0300	oxidoreductase activity
HI798_24135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HI798_24135	COG0318	PFAM AMP-dependent synthetase and ligase
HI798_24150	COG2192	nodulation
HI798_24155	COG0318	PFAM AMP-dependent synthetase and ligase
HI798_24180	COG0525	valine-tRNA ligase activity
HI798_24195	COG3916	Acyl-homoserine-lactone synthase
HI798_24200	COG2197	response regulator
HI798_24310	COG3039	Transposase
HI798_24335	COG3039	Transposase
HI798_24350	COG3501	Rhs element vgr protein
HI798_24445	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HI798_24460	COG3039	Transposase
HI798_24475	COG1999	signal sequence binding
HI798_24495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HI798_24500	COG1301	dicarboxylic acid transport
HI798_24510	COG0583	DNA-binding transcription factor activity
HI798_24555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HI798_24565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HI798_24585	COG0110	maltose O-acetyltransferase activity
HI798_24600	COG2244	polysaccharide biosynthetic process
HI798_24605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HI798_24610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HI798_24615	COG3206	protein involved in exopolysaccharide biosynthesis
HI798_24615	COG0489	protein tyrosine kinase activity
HI798_24620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HI798_24625	COG1596	polysaccharide export
HI798_24670	COG0840	transmembrane signaling receptor activity
HI798_24710	COG3220	belongs to the UPF0276 family
HI798_24745	COG0745	RESPONSE REGULATOR receiver
HI798_24770	COG2223	nitrite transmembrane transporter activity
HI798_24775	COG0243	molybdopterin cofactor binding
HI798_24785	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HI798_24790	COG3300	MHYT domain
HI798_24790	COG5001	Diguanylate cyclase
HI798_24795	COG3158	transport of potassium into the cell
HI798_24800	COG1278	Cold shock
HI798_24825	COG4689	acetoacetate decarboxylase
HI798_24830	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_24840	COG0673	inositol 2-dehydrogenase activity
HI798_24900	COG5444	nuclease activity
HI798_24930	COG2831	hemolysin activation secretion protein
HI798_24935	COG0673	inositol 2-dehydrogenase activity
HI798_24990	COG4964	Belongs to the GSP D family
HI798_25030	COG2197	response regulator
HI798_25055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HI798_25070	COG1877	trehalose-phosphatase activity
HI798_25075	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HI798_25080	COG1846	Transcriptional regulator
HI798_25085	COG1764	response to oxidative stress
HI798_25100	COG0583	DNA-binding transcription factor activity
HI798_25110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI798_25165	COG1064	alcohol dehydrogenase
HI798_25185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HI798_25190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HI798_25195	COG0640	Transcriptional regulator
HI798_25225	COG5444	nuclease activity
HI798_25235	COG3501	Rhs element vgr protein
HI798_25245	COG2197	response regulator
HI798_25255	COG2066	Belongs to the glutaminase family
HI798_25260	COG4149	molybdate abc transporter
HI798_25265	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HI798_25280	COG5001	Diguanylate cyclase
HI798_25280	COG3300	MHYT domain
HI798_25300	COG3813	Protein conserved in bacteria
HI798_25315	COG0745	RESPONSE REGULATOR receiver
HI798_25320	COG2205	protein histidine kinase activity
HI798_25350	COG1858	cytochrome C peroxidase
HI798_25370	COG1253	flavin adenine dinucleotide binding
HI798_25375	COG1858	cytochrome C peroxidase
HI798_25415	COG2274	protein secretion by the type I secretion system
HI798_25440	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HI798_25455	COG0800	Aldolase
HI798_25460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HI798_25465	COG2197	response regulator
HI798_25485	COG0745	RESPONSE REGULATOR receiver
HI798_25530	COG1294	oxidase, subunit
HI798_25535	COG1271	oxidase subunit
HI798_25540	COG3300	MHYT domain
HI798_25540	COG5001	Diguanylate cyclase
HI798_25545	COG0840	transmembrane signaling receptor activity
HI798_25555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HI798_25565	COG0534	Mate efflux family protein
HI798_25580	COG0243	molybdopterin cofactor binding
HI798_25585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HI798_25595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HI798_25600	COG2223	nitrite transmembrane transporter activity
HI798_25605	COG0840	transmembrane signaling receptor activity
HI798_25610	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HI798_25620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HI798_25640	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HI798_25645	COG0436	Aminotransferase
HI798_25650	COG0473	3-isopropylmalate dehydrogenase activity
HI798_25650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HI798_25680	COG3039	Transposase
HI798_25695	COG3039	Transposase
HI798_25705	COG0840	transmembrane signaling receptor activity
HI798_25710	COG0567	Dehydrogenase, E1 component
HI798_25715	COG0204	Acyl-transferase
HI798_25730	COG4263	nitrous-oxide reductase activity
HI798_25785	COG3039	Transposase
HI798_25800	COG2831	hemolysin activation secretion protein
HI798_25835	COG2824	Alkylphosphonate utilization operon protein PhnA
HI798_25845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HI798_25855	COG0762	integral membrane protein
HI798_25880	COG1191	sigma factor activity
HI798_25895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HI798_25905	COG1309	transcriptional regulator
HI798_25910	COG2271	Major facilitator Superfamily
HI798_25915	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HI798_25920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HI798_25925	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_25935	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HI798_25940	COG0745	RESPONSE REGULATOR receiver
HI798_25945	COG2201	protein-glutamate methylesterase activity
HI798_25950	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HI798_25960	COG0840	transmembrane signaling receptor activity
HI798_25965	COG0835	chemotaxis
HI798_25975	COG0745	RESPONSE REGULATOR receiver
HI798_25980	COG1360	Flagellar Motor Protein
HI798_26015	COG0477	Major facilitator Superfamily
HI798_26020	COG2267	carboxylic ester hydrolase activity
HI798_26025	COG3321	synthase
HI798_26025	COG0318	PFAM AMP-dependent synthetase and ligase
HI798_26025	COG0300	oxidoreductase activity
HI798_26025	COG1028	Short-chain dehydrogenase reductase Sdr
HI798_26025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HI798_26030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HI798_26040	COG0644	oxidoreductase
HI798_26045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HI798_26050	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HI798_26080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI798_26080	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HI798_26115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HI798_26115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HI798_26120	COG1045	serine acetyltransferase
HI798_26125	COG2205	protein histidine kinase activity
HI798_26150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HI798_26160	COG0469	pyruvate kinase activity
HI798_26170	COG0583	DNA-binding transcription factor activity
HI798_26185	COG2205	protein histidine kinase activity
HI798_26190	COG0745	RESPONSE REGULATOR receiver
HI798_26200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI798_26210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HI798_26235	COG1136	(ABC) transporter
HI798_26240	COG1136	(ABC) transporter
HI798_26240	COG0577	efflux transmembrane transporter activity
HI798_26265	COG3039	Transposase
HI798_26295	COG0667	Aldo Keto reductase
HI798_26380	COG2192	nodulation
HI798_26400	COG4651	solute:proton antiporter activity
HI798_26400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HI798_26445	COG3256	nitric oxide reductase
HI798_26450	COG2188	Transcriptional regulator
HI798_26455	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HI798_26460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HI798_26495	COG0583	DNA-binding transcription factor activity
HI798_26550	COG0705	Rhomboid family
HI798_26570	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
HI798_26590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HI798_26605	COG3210	domain, Protein
HI798_26615	COG3039	Transposase
HI798_26620	COG3039	Transposase
HI798_26660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HI798_26665	COG0642	Histidine kinase
HI798_26670	COG0745	RESPONSE REGULATOR receiver
HI798_26685	COG0837	glucose binding
HI798_26695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HI798_26705	COG0589	response to stress
HI798_26720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HI798_26725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HI798_26735	COG1845	cytochrome c oxidase, subunit III
HI798_26760	COG2271	Major facilitator Superfamily
HI798_26775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HI798_26785	COG0765	amino acid transport
HI798_26790	COG0010	Belongs to the arginase family
HI798_26795	COG2197	response regulator
HI798_26820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HI798_26825	COG1012	belongs to the aldehyde dehydrogenase family
HI798_26835	COG0583	DNA-binding transcription factor activity
HI798_26860	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HI798_26865	COG2814	Major facilitator Superfamily
HI798_26880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HI798_26940	COG1012	belongs to the aldehyde dehydrogenase family
HI798_26945	COG0473	3-isopropylmalate dehydrogenase activity
HI798_26955	COG2271	Major facilitator Superfamily
HI798_26960	COG2721	sulfolactate sulfo-lyase activity
HI798_26970	COG1475	DNA binding
HI798_26980	COG3969	phosphoadenosine phosphosulfate
HI798_26985	COG5295	Hep Hag repeat protein
HI798_26985	COG5295	Hep Hag repeat protein
HI798_26995	COG0784	Response regulator, receiver
HI798_26995	COG2205	protein histidine kinase activity
HI798_27000	COG4251	negative regulation of phosphorylation
HI798_27000	COG3706	GGDEF domain
HI798_27000	COG2203	Gaf domain
HI798_27000	COG5001	Diguanylate cyclase
HI798_27045	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
HI798_27055	COG4213	ABC transporter substrate-binding protein
HI798_27060	COG1129	ABC transporter
HI798_27065	COG4214	carbohydrate transport
HI798_27070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HI798_27075	COG1609	Transcriptional regulator
HI798_27085	COG2207	Transcriptional regulator
HI798_27145	COG1595	DNA-templated transcription, initiation
HI798_27175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HI798_27185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HI798_27195	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HI798_27220	COG2204	response regulator
HI798_27240	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HI798_27260	COG2205	protein histidine kinase activity
HI798_27270	COG2252	PERMEase