locus-tag	class	description
CFM90_00045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFM90_00065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFM90_00070	COG0081	regulation of translation
CFM90_00075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFM90_00080	COG0222	ribosome binding
CFM90_00085	COG0085	RNA polymerase activity
CFM90_00090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFM90_00095	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CFM90_00100	COG3234	Protein of unknown function (DUF1175)
CFM90_00105	COG2373	Large extracellular alpha-helical protein
CFM90_00110	COG5445	Predicted secreted protein (DUF2300)
CFM90_00115	COG4676	Protein conserved in bacteria
CFM90_00120	COG4676	Protein conserved in bacteria
CFM90_00130	COG0514	ATP-dependent DNA helicase (RecQ)
CFM90_00135	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFM90_00140	COG0049	tRNA binding
CFM90_00145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFM90_00150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFM90_00155	COG0051	transcription antitermination factor activity, RNA binding
CFM90_00160	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFM90_00165	COG0088	Forms part of the polypeptide exit tunnel
CFM90_00170	COG0089	rRNA binding
CFM90_00175	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFM90_00180	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFM90_00185	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFM90_00190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFM90_00195	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFM90_00200	COG0255	Belongs to the universal ribosomal protein uL29 family
CFM90_00205	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFM90_00210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFM90_00215	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFM90_00220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFM90_00225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFM90_00230	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFM90_00235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFM90_00240	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFM90_00245	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFM90_00250	COG1841	ribosomal large subunit assembly
CFM90_00255	COG0200	Binds to the 23S rRNA
CFM90_00260	COG0201	protein transport
CFM90_00265	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFM90_00270	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFM90_00275	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFM90_00280	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFM90_00285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFM90_00290	COG0202	RNA polymerase activity
CFM90_00295	COG0203	ribosomal protein L17
CFM90_00305	COG4232	protein-disulfide reductase activity
CFM90_00315	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CFM90_00325	COG1333	cytochrome c biogenesis protein
CFM90_00330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFM90_00350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFM90_00355	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CFM90_00370	COG1965	Belongs to the frataxin family
CFM90_00375	COG3385	transposase activity
CFM90_00410	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFM90_00415	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFM90_00420	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CFM90_00425	COG3047	cAMP biosynthetic process
CFM90_00435	COG0070	glutamate synthase
CFM90_00435	COG0069	glutamate synthase activity
CFM90_00435	COG0067	glutamate synthase
CFM90_00450	COG1127	ABC transporter
CFM90_00455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFM90_00460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CFM90_00480	COG1131	(ABC) transporter
CFM90_00485	COG0842	Transport permease protein
CFM90_00495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFM90_00500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFM90_00505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFM90_00510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFM90_00515	COG0131	Imidazoleglycerol-phosphate dehydratase
CFM90_00520	COG2095	MarC family integral membrane protein
CFM90_00525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFM90_00530	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFM90_00535	COG0107	imidazoleglycerol-phosphate synthase activity
CFM90_00540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFM90_00545	COG0140	phosphoribosyl-ATP diphosphatase activity
CFM90_00555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFM90_00560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFM90_00565	COG0805	protein transport
CFM90_00570	COG3385	transposase activity
CFM90_00575	COG3842	ATPase activity
CFM90_00585	COG1840	ABC-type Fe3 transport system, periplasmic component
CFM90_00605	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_00610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFM90_00615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFM90_00620	COG1970	mechanosensitive ion channel activity
CFM90_00625	COG0723	plastoquinol--plastocyanin reductase activity
CFM90_00630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CFM90_00635	COG2857	Cytochrome c1
CFM90_00640	COG0625	glutathione transferase activity
CFM90_00645	COG2969	positive regulation of protein catabolic process
CFM90_00670	COG0405	Gamma-glutamyltransferase
CFM90_00680	COG3712	iron ion homeostasis
CFM90_00690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFM90_00705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFM90_00710	COG0488	(ABC) transporter
CFM90_00730	COG2943	transferase activity, transferring hexosyl groups
CFM90_00730	COG3416	Protein conserved in bacteria
CFM90_00735	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CFM90_00750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CFM90_00755	COG2890	protein-(glutamine-N5) methyltransferase activity
CFM90_00765	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFM90_00770	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CFM90_00780	COG0012	GTP binding
CFM90_00810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFM90_00815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFM90_00820	COG0604	alcohol dehydrogenase
CFM90_00830	COG1289	transmembrane transporter activity
CFM90_00845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFM90_00855	COG0134	indole-3-glycerol-phosphate synthase activity
CFM90_00860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFM90_00870	COG0512	Glutamine amidotransferase of anthranilate synthase
CFM90_00880	COG0546	phosphoglycolate phosphatase activity
CFM90_00890	COG2967	ApaG domain
CFM90_00910	COG2050	protein possibly involved in aromatic compounds catabolism
CFM90_00915	COG1024	Enoyl-CoA hydratase
CFM90_00920	COG1024	Enoyl-CoA hydratase
CFM90_00950	COG1473	amidohydrolase
CFM90_00955	COG0747	negative chemotaxis
CFM90_00960	COG0601	transmembrane transport
CFM90_00965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFM90_00970	COG0444	Belongs to the ABC transporter superfamily
CFM90_00975	COG4608	Belongs to the ABC transporter superfamily
CFM90_00985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFM90_00985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFM90_00990	COG1105	Belongs to the carbohydrate kinase PfkB family
CFM90_00995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFM90_00995	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFM90_01000	COG1609	Transcriptional regulator
CFM90_01005	COG0243	molybdopterin cofactor binding
CFM90_01015	COG0318	PFAM AMP-dependent synthetase and ligase
CFM90_01020	COG0477	Major facilitator Superfamily
CFM90_01025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_01030	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CFM90_01035	COG2001	Belongs to the MraZ family
CFM90_01040	COG0275	rRNA processing
CFM90_01055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFM90_01060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CFM90_01065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFM90_01070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFM90_01080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFM90_01085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFM90_01090	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFM90_01095	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFM90_01110	COG0678	peroxiredoxin activity
CFM90_01115	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CFM90_01125	COG0739	heme binding
CFM90_01130	COG0653	protein targeting
CFM90_01135	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFM90_01145	COG0494	nUDIX hydrolase
CFM90_01150	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CFM90_01155	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CFM90_01160	COG0237	dephospho-CoA kinase activity
CFM90_01170	COG1459	type II secretion system
CFM90_01180	COG4536	flavin adenine dinucleotide binding
CFM90_01190	COG0142	geranyltranstransferase activity
CFM90_01195	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFM90_01200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFM90_01205	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFM90_01210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFM90_01220	COG0494	nUDIX hydrolase
CFM90_01225	COG0442	prolyl-tRNA aminoacylation
CFM90_01230	COG0741	lytic transglycosylase activity
CFM90_01240	COG2095	MarC family integral membrane protein
CFM90_01250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFM90_01275	COG3023	N-Acetylmuramoyl-L-alanine amidase
CFM90_01300	COG1522	sequence-specific DNA binding
CFM90_01310	COG0840	transmembrane signaling receptor activity
CFM90_01360	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CFM90_01370	COG2264	protein methyltransferase activity
CFM90_01380	COG0511	ligase activity, forming carbon-carbon bonds
CFM90_01385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFM90_01390	COG3118	belongs to the thioredoxin family
CFM90_01400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFM90_01405	COG3150	esterase
CFM90_01410	COG3161	chorismate lyase activity
CFM90_01415	COG0557	exoribonuclease II activity
CFM90_01425	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFM90_01430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFM90_01445	COG0284	orotidine-5'-phosphate decarboxylase activity
CFM90_01455	COG1058	Belongs to the CinA family
CFM90_01455	COG1546	Belongs to the CinA family
CFM90_01460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CFM90_01470	COG0280	phosphate acetyltransferase
CFM90_01470	COG0281	malic enzyme
CFM90_01490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CFM90_01500	COG0583	DNA-binding transcription factor activity
CFM90_01505	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_01520	COG1129	ABC transporter
CFM90_01530	COG3039	Transposase
CFM90_01550	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_01555	COG0800	Aldolase
CFM90_01560	COG4948	Mandelate Racemase Muconate Lactonizing
CFM90_01565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFM90_01570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CFM90_01575	COG0583	DNA-binding transcription factor activity
CFM90_01580	COG0735	belongs to the Fur family
CFM90_01585	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFM90_01590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFM90_01595	COG0495	leucyl-tRNA aminoacylation
CFM90_01605	COG1466	dna polymerase III delta subunit
CFM90_01610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFM90_01625	COG2204	response regulator
CFM90_01630	COG4191	Histidine kinase
CFM90_01635	COG4191	Histidine kinase
CFM90_01650	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CFM90_01655	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CFM90_01660	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CFM90_01665	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CFM90_01700	COG0482	sulfurtransferase activity
CFM90_01705	COG0069	glutamate synthase activity
CFM90_01710	COG0625	glutathione transferase activity
CFM90_01720	COG3038	cytochrome b561
CFM90_01730	COG2353	YceI-like domain
CFM90_01735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFM90_01740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFM90_01745	COG1862	Preprotein translocase
CFM90_01750	COG0343	queuine tRNA-ribosyltransferase activity
CFM90_01755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFM90_01760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFM90_01785	COG0583	DNA-binding transcription factor activity
CFM90_01800	COG1522	sequence-specific DNA binding
CFM90_01805	COG1473	amidohydrolase
CFM90_01810	COG1819	glycosyl
CFM90_01825	COG3039	Transposase
CFM90_01860	COG1278	Cold shock
CFM90_01865	COG3385	transposase activity
CFM90_01955	COG0783	Belongs to the Dps family
CFM90_01960	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CFM90_02020	COG0386	Belongs to the glutathione peroxidase family
CFM90_02040	COG1346	cytolysis
CFM90_02045	COG1380	Effector of murein hydrolase LrgA
CFM90_02050	COG0247	lactate metabolic process
CFM90_02055	COG0277	FAD linked oxidase domain protein
CFM90_02060	COG0277	FAD linked oxidase domain protein
CFM90_02065	COG0583	DNA-binding transcription factor activity
CFM90_02070	COG0277	FAD linked oxidase domain protein
CFM90_02075	COG2096	Adenosyltransferase
CFM90_02080	COG0668	transmembrane transport
CFM90_02090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFM90_02095	COG0312	modulator of DNA gyrase
CFM90_02100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFM90_02110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFM90_02125	COG1404	Belongs to the peptidase S8 family
CFM90_02135	COG0497	DNA recombination
CFM90_02140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFM90_02145	COG1420	regulation of RNA biosynthetic process
CFM90_02155	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFM90_02160	COG2986	histidine ammonia-lyase
CFM90_02165	COG0010	Belongs to the arginase family
CFM90_02170	COG1228	amidohydrolase
CFM90_02175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CFM90_02195	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFM90_02205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFM90_02210	COG0443	Heat shock 70 kDa protein
CFM90_02215	COG0484	heat shock protein binding
CFM90_02220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFM90_02220	COG0512	Glutamine amidotransferase of anthranilate synthase
CFM90_02225	COG1122	ATPase activity
CFM90_02230	COG4662	Binding-protein-dependent transport system inner membrane component
CFM90_02235	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CFM90_02245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFM90_02260	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFM90_02265	COG0628	permease
CFM90_02270	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFM90_02285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFM90_02285	COG2169	Transcriptional regulator
CFM90_02305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFM90_02305	COG2169	Transcriptional regulator
CFM90_02310	COG0456	acetyltransferase
CFM90_02315	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFM90_02320	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFM90_02325	COG3008	intermembrane lipid transfer
CFM90_02340	COG0586	Pfam SNARE associated Golgi protein
CFM90_02350	COG0728	peptidoglycan biosynthetic process
CFM90_02355	COG0268	Binds directly to 16S ribosomal RNA
CFM90_02365	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFM90_02375	COG0137	argininosuccinate synthase activity
CFM90_02380	COG3123	guanosine phosphorylase activity
CFM90_02390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFM90_02395	COG1666	GTP binding
CFM90_02405	COG2366	antibiotic biosynthetic process
CFM90_02410	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CFM90_02420	COG4974	Belongs to the 'phage' integrase family
CFM90_02435	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFM90_02440	COG0802	atpase or kinase
CFM90_02445	COG0860	N-Acetylmuramoyl-L-alanine amidase
CFM90_02455	COG0583	DNA-binding transcription factor activity
CFM90_02475	COG0563	adenylate kinase activity
CFM90_02480	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CFM90_02485	COG2835	tetraacyldisaccharide 4'-kinase activity
CFM90_02490	COG1663	tetraacyldisaccharide 4'-kinase activity
CFM90_02500	COG0811	peptide transport
CFM90_02505	COG1570	exodeoxyribonuclease VII activity
CFM90_02510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFM90_02550	COG2610	gluconate transmembrane transporter activity
CFM90_02585	COG1473	amidohydrolase
CFM90_02620	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_02625	COG2321	neutral zinc metallopeptidase
CFM90_02640	COG2259	Doxx family
CFM90_02650	COG0583	DNA-binding transcription factor activity
CFM90_02655	COG0583	DNA-binding transcription factor activity
CFM90_02675	COG1858	cytochrome C peroxidase
CFM90_02710	COG1278	Cold shock
CFM90_02715	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFM90_02720	COG0542	response to heat
CFM90_02725	COG0756	dUTP diphosphatase activity
CFM90_02730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFM90_02735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFM90_02745	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFM90_02750	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFM90_02755	COG0196	riboflavin kinase activity
CFM90_02760	COG0784	Response regulator, receiver
CFM90_02760	COG5002	protein histidine kinase activity
CFM90_02770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFM90_02775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFM90_02775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFM90_02785	COG3264	Mechanosensitive ion channel
CFM90_02785	COG1511	domain protein
CFM90_02795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFM90_02805	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CFM90_02810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFM90_02815	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFM90_02820	COG2003	Belongs to the UPF0758 family
CFM90_02825	COG1047	Peptidyl-prolyl cis-trans
CFM90_02830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CFM90_02850	COG0411	ABC transporter
CFM90_02865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFM90_02880	COG3706	GGDEF domain
CFM90_02900	COG2084	Dehydrogenase
CFM90_02910	COG0583	DNA-binding transcription factor activity
CFM90_02920	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFM90_02930	COG0175	sulfate reduction
CFM90_02940	COG2895	sulfate adenylyltransferase (ATP) activity
CFM90_02970	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFM90_02985	COG0129	dihydroxy-acid dehydratase activity
CFM90_02990	COG0583	DNA-binding transcription factor activity
CFM90_02995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFM90_03030	COG4206	TonB-dependent receptor
CFM90_03040	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFM90_03045	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CFM90_03050	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CFM90_03060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CFM90_03070	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CFM90_03080	COG1492	cobalamin metabolic process
CFM90_03095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFM90_03100	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFM90_03115	COG2911	Protein conserved in bacteria
CFM90_03125	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFM90_03125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFM90_03130	COG2885	chlorophyll binding
CFM90_03130	COG3047	cAMP biosynthetic process
CFM90_03135	COG0489	protein tyrosine kinase activity
CFM90_03165	COG0243	molybdopterin cofactor binding
CFM90_03165	COG3383	formate dehydrogenase (NAD+) activity
CFM90_03170	COG0437	4 iron, 4 sulfur cluster binding
CFM90_03190	COG2032	superoxide dismutase activity
CFM90_03195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFM90_03200	COG0717	Belongs to the dCTP deaminase family
CFM90_03205	COG1982	Orn Lys Arg decarboxylase major
CFM90_03215	COG0165	Argininosuccinate lyase
CFM90_03240	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CFM90_03245	COG0181	hydroxymethylbilane synthase activity
CFM90_03270	COG2271	Major facilitator Superfamily
CFM90_03285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFM90_03300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFM90_03300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CFM90_03325	COG0492	ferredoxin-NADP+ reductase activity
CFM90_03330	COG1674	ftsk spoiiie
CFM90_03335	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CFM90_03345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFM90_03350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFM90_03360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFM90_03385	COG4584	PFAM Integrase catalytic
CFM90_03390	COG1484	DNA-dependent DNA replication
CFM90_03470	COG2165	general secretion pathway protein
CFM90_03540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFM90_03590	COG1253	flavin adenine dinucleotide binding
CFM90_03645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFM90_03660	COG0765	amino acid transport
CFM90_03665	COG0765	amino acid transport
CFM90_03670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFM90_03680	COG1414	Transcriptional regulator
CFM90_03690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFM90_03705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFM90_03710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFM90_03725	COG0411	ABC transporter
CFM90_03730	COG0410	ABC transporter
CFM90_03735	COG0683	leucine binding
CFM90_03750	COG2342	PFAM TM1410 hypothetical-related protein
CFM90_03760	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFM90_03775	COG0525	valine-tRNA ligase activity
CFM90_03780	COG0210	DNA helicase
CFM90_03790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFM90_03800	COG1611	Belongs to the LOG family
CFM90_03805	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFM90_03805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFM90_03810	COG1252	NADH dehydrogenase
CFM90_03815	COG0412	Dienelactone hydrolase
CFM90_03845	COG1722	exodeoxyribonuclease VII activity
CFM90_03850	COG0142	geranyltranstransferase activity
CFM90_03855	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFM90_03860	COG1469	GTP cyclohydrolase I activity
CFM90_03865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFM90_03870	COG2081	HI0933 family
CFM90_03875	COG1610	YqeY-like protein
CFM90_03885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFM90_03895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFM90_03905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFM90_03905	COG0426	domain, Protein
CFM90_03910	COG0513	Belongs to the DEAD box helicase family
CFM90_03915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFM90_03920	COG0583	DNA-binding transcription factor activity
CFM90_03925	COG1741	Belongs to the pirin family
CFM90_03965	COG1132	(ABC) transporter
CFM90_03980	COG1530	ribonuclease E activity
CFM90_03985	COG0424	maF-like protein
CFM90_03995	COG0799	negative regulation of ribosome biogenesis
CFM90_04005	COG0408	coproporphyrinogen oxidase activity
CFM90_04010	COG0151	Belongs to the GarS family
CFM90_04015	COG0217	transcriptional regulatory protein
CFM90_04020	COG0433	COG0433 Predicted ATPase
CFM90_04025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFM90_04030	COG0697	spore germination
CFM90_04035	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_04040	COG1803	Methylglyoxal synthase
CFM90_04095	COG1129	ABC transporter
CFM90_04100	COG2814	Major facilitator Superfamily
CFM90_04105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CFM90_04110	COG1984	allophanate hydrolase subunit 2
CFM90_04115	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFM90_04130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFM90_04135	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CFM90_04150	COG1234	tRNA 3'-trailer cleavage
CFM90_04160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFM90_04175	COG0243	molybdopterin cofactor binding
CFM90_04195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFM90_04200	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFM90_04205	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFM90_04215	COG0515	serine threonine protein kinase
CFM90_04215	COG3064	Membrane
CFM90_04215	COG4991	sh3 domain protein
CFM90_04220	COG1561	YicC-like family, N-terminal region
CFM90_04225	COG0194	GDP metabolic process
CFM90_04230	COG1758	RNA polymerase activity
CFM90_04235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFM90_04265	COG1652	LysM domain
CFM90_04275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFM90_04300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFM90_04305	COG3842	ATPase activity
CFM90_04320	COG1733	regulation of RNA biosynthetic process
CFM90_04325	COG0166	Belongs to the GPI family
CFM90_04325	COG0166	Belongs to the GPI family
CFM90_04330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_04355	COG0246	Mannitol dehydrogenase
CFM90_04360	COG1070	Carbohydrate kinase
CFM90_04365	COG2390	Transcriptional regulator
CFM90_04375	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CFM90_04380	COG0308	aminopeptidase N
CFM90_04390	COG0280	phosphate acetyltransferase
CFM90_04390	COG0281	malic enzyme
CFM90_04400	COG3195	allantoin biosynthetic process
CFM90_04400	COG3648	Uricase
CFM90_04415	COG2233	PERMEase
CFM90_04425	COG2351	hydroxyisourate hydrolase activity
CFM90_04440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFM90_04445	COG2271	Major facilitator Superfamily
CFM90_04450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFM90_04455	COG1012	belongs to the aldehyde dehydrogenase family
CFM90_04465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_04475	COG1126	abc transporter atp-binding protein
CFM90_04480	COG0765	amino acid transport
CFM90_04485	COG0765	amino acid transport
CFM90_04495	COG2186	Transcriptional regulator
CFM90_04510	COG2119	membrane
CFM90_04515	COG0402	S-adenosylhomocysteine deaminase activity
CFM90_04520	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFM90_04530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFM90_04555	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CFM90_04580	COG1309	transcriptional regulator
CFM90_04590	COG0438	transferase activity, transferring glycosyl groups
CFM90_04625	COG0028	Belongs to the TPP enzyme family
CFM90_04635	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFM90_04640	COG0688	phosphatidylethanolamine metabolic process
CFM90_04645	COG1183	phosphatidylcholine synthase activity
CFM90_04650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFM90_04660	COG0683	leucine binding
CFM90_04665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFM90_04670	COG1185	polyribonucleotide nucleotidyltransferase activity
CFM90_04685	COG0149	triose-phosphate isomerase activity
CFM90_04690	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFM90_04700	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFM90_04705	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFM90_04710	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFM90_04715	COG0649	NAD binding
CFM90_04730	COG1034	ATP synthesis coupled electron transport
CFM90_04735	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CFM90_04740	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFM90_04750	COG0713	ATP synthesis coupled electron transport
CFM90_04765	COG1007	ATP synthesis coupled electron transport
CFM90_04785	COG1960	acyl-CoA dehydrogenase activity
CFM90_04790	COG1960	acyl-CoA dehydrogenase activity
CFM90_04795	COG1012	belongs to the aldehyde dehydrogenase family
CFM90_04795	COG2030	dehydratase
CFM90_04820	COG0411	ABC transporter
CFM90_04830	COG0829	nickel cation binding
CFM90_04835	COG0831	urea catabolic process
CFM90_04845	COG0832	Belongs to the urease beta subunit family
CFM90_04850	COG0804	urea catabolic process
CFM90_04855	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CFM90_04860	COG0830	nickel cation binding
CFM90_04865	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFM90_04890	COG0625	glutathione transferase activity
CFM90_04895	COG1960	acyl-CoA dehydrogenase activity
CFM90_04925	COG1024	Enoyl-CoA hydratase
CFM90_04930	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFM90_04935	COG0625	glutathione transferase activity
CFM90_04940	COG0436	Aminotransferase
CFM90_04950	COG3022	response to hydroperoxide
CFM90_04955	COG2866	Carboxypeptidase
CFM90_04965	COG0747	negative chemotaxis
CFM90_04980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFM90_05005	COG0039	L-malate dehydrogenase activity
CFM90_05010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFM90_05020	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CFM90_05025	COG1053	succinate dehydrogenase
CFM90_05030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CFM90_05035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CFM90_05040	COG0372	Belongs to the citrate synthase family
CFM90_05045	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFM90_05050	COG0066	3-isopropylmalate dehydratase activity
CFM90_05055	COG0473	3-isopropylmalate dehydrogenase activity
CFM90_05070	COG0101	tRNA pseudouridine synthase activity
CFM90_05075	COG0135	phosphoribosylanthranilate isomerase activity
CFM90_05080	COG0133	tryptophan synthase activity
CFM90_05090	COG0159	tryptophan synthase activity
CFM90_05095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFM90_05100	COG0285	dihydrofolate synthase activity
CFM90_05120	COG0842	Transport permease protein
CFM90_05125	COG1131	(ABC) transporter
CFM90_05150	COG3385	transposase activity
CFM90_05165	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CFM90_05210	COG1301	dicarboxylic acid transport
CFM90_05215	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFM90_05230	COG0697	spore germination
CFM90_05235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFM90_05240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFM90_05250	COG3039	Transposase
CFM90_05260	COG2197	response regulator
CFM90_05265	COG0840	transmembrane signaling receptor activity
CFM90_05270	COG3706	GGDEF domain
CFM90_05270	COG0745	RESPONSE REGULATOR receiver
CFM90_05305	COG0747	negative chemotaxis
CFM90_05325	COG0601	transmembrane transport
CFM90_05330	COG2072	flavoprotein involved in K transport
CFM90_05375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFM90_05385	COG3547	Transposase (IS116 IS110 IS902 family)
CFM90_05420	COG0656	L-ascorbic acid biosynthetic process
CFM90_05425	COG2304	oxidoreductase activity
CFM90_05440	COG0589	response to stress
CFM90_05475	COG0328	RNA-DNA hybrid ribonuclease activity
CFM90_05480	COG2226	methyltransferase
CFM90_05485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFM90_05490	COG1388	LysM domain
CFM90_05490	COG0741	lytic transglycosylase activity
CFM90_05495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFM90_05500	COG0505	Belongs to the CarA family
CFM90_05510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFM90_05515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFM90_05525	COG1534	Rna-binding protein
CFM90_05530	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CFM90_05535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFM90_05540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFM90_05545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFM90_05550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFM90_05555	COG0573	inorganic phosphate transmembrane transporter activity
CFM90_05560	COG0581	inorganic phosphate transmembrane transporter activity
CFM90_05565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFM90_05575	COG0745	RESPONSE REGULATOR receiver
CFM90_05585	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CFM90_05590	COG0248	Ppx GppA phosphatase
CFM90_05615	COG0730	response to heat
CFM90_05625	COG0640	Transcriptional regulator
CFM90_05635	COG3300	MHYT domain
CFM90_05635	COG5001	Diguanylate cyclase
CFM90_05645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CFM90_05650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CFM90_05695	COG1522	sequence-specific DNA binding
CFM90_05710	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_05720	COG2814	Major facilitator Superfamily
CFM90_05730	COG1846	Transcriptional regulator
CFM90_05795	COG0277	FAD linked oxidase domain protein
CFM90_05810	COG1295	ribonuclease BN
CFM90_05835	COG0477	Major facilitator Superfamily
CFM90_05840	COG0545	Peptidyl-prolyl cis-trans isomerase
CFM90_05845	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFM90_05855	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_05860	COG4566	intracellular signal transduction
CFM90_05875	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_05885	COG0251	oxidation-reduction process
CFM90_05890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFM90_05900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFM90_05905	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFM90_05910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFM90_05915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFM90_05920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFM90_05925	COG0072	phenylalanine-tRNA ligase activity
CFM90_05925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFM90_05930	COG0776	regulation of translation
CFM90_05960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFM90_05965	COG0531	amino acid
CFM90_05985	COG1846	Transcriptional regulator
CFM90_05995	COG0402	S-adenosylhomocysteine deaminase activity
CFM90_06000	COG0339	signal peptide processing
CFM90_06005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFM90_06010	COG4566	intracellular signal transduction
CFM90_06025	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CFM90_06030	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFM90_06040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFM90_06055	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFM90_06080	COG1414	Transcriptional regulator
CFM90_06105	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CFM90_06110	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CFM90_06130	COG0167	dihydroorotate dehydrogenase activity
CFM90_06140	COG3158	transport of potassium into the cell
CFM90_06150	COG2183	response to ionizing radiation
CFM90_06165	COG1199	ATP-dependent helicase activity
CFM90_06175	COG0564	pseudouridine synthase activity
CFM90_06190	COG3243	poly(R)-hydroxyalkanoic acid synthase
CFM90_06195	COG0183	Belongs to the thiolase family
CFM90_06200	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_06210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFM90_06215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFM90_06220	COG0183	Belongs to the thiolase family
CFM90_06235	COG0560	Phosphoserine phosphatase
CFM90_06245	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFM90_06250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFM90_06255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFM90_06260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFM90_06265	COG0450	alkyl hydroperoxide reductase
CFM90_06270	COG2205	protein histidine kinase activity
CFM90_06275	COG0745	RESPONSE REGULATOR receiver
CFM90_06295	COG1562	ergosterol biosynthetic process
CFM90_06300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFM90_06320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFM90_06320	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFM90_06325	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFM90_06330	COG0740	serine-type endopeptidase activity
CFM90_06335	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFM90_06340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFM90_06345	COG0776	regulation of translation
CFM90_06360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFM90_06365	COG3385	transposase activity
CFM90_06380	COG4181	ATPase activity
CFM90_06385	COG0166	Belongs to the GPI family
CFM90_06390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFM90_06400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFM90_06400	COG0047	phosphoribosylformylglycinamidine synthase activity
CFM90_06420	COG0535	radical SAM domain protein
CFM90_06440	COG0583	DNA-binding transcription factor activity
CFM90_06445	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_06455	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFM90_06465	COG3842	ATPase activity
CFM90_06470	COG0642	Histidine kinase
CFM90_06480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_06485	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFM90_06510	COG1126	abc transporter atp-binding protein
CFM90_06525	COG2917	probably involved in intracellular septation
CFM90_06530	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFM90_06535	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFM90_06540	COG0318	PFAM AMP-dependent synthetase and ligase
CFM90_06550	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFM90_06565	COG0410	ABC transporter
CFM90_06580	COG0833	amino acid
CFM90_06585	COG0833	amino acid
CFM90_06595	COG1335	isochorismatase
CFM90_06600	COG0183	Belongs to the thiolase family
CFM90_06605	COG1960	acyl-CoA dehydrogenase activity
CFM90_06610	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_06625	COG2130	NADP-dependent
CFM90_06645	COG0596	Alpha beta hydrolase
CFM90_06680	COG3039	Transposase
CFM90_06685	COG2831	hemolysin activation secretion protein
CFM90_06705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFM90_06710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFM90_06715	COG0470	DNA polymerase III
CFM90_06725	COG0084	hydrolase, TatD family'
CFM90_06735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CFM90_06740	COG1609	Transcriptional regulator
CFM90_06745	COG1840	ABC-type Fe3 transport system, periplasmic component
CFM90_06755	COG4208	sulfate ABC transporter
CFM90_06760	COG3842	ATPase activity
CFM90_06765	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CFM90_06770	COG3023	N-Acetylmuramoyl-L-alanine amidase
CFM90_06810	COG2226	methyltransferase
CFM90_06820	COG3433	isochorismatase activity
CFM90_06820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFM90_06820	COG2226	methyltransferase
CFM90_06825	COG4771	TonB-dependent receptor
CFM90_06845	COG3433	isochorismatase activity
CFM90_06845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFM90_06845	COG2226	methyltransferase
CFM90_06860	COG2201	protein-glutamate methylesterase activity
CFM90_06865	COG0456	acetyltransferase
CFM90_06910	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFM90_06955	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CFM90_06985	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CFM90_07010	COG2801	Transposase and inactivated derivatives
CFM90_07040	COG2814	Major facilitator Superfamily
CFM90_07065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFM90_07075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFM90_07120	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CFM90_07125	COG0156	8-amino-7-oxononanoate synthase activity
CFM90_07160	COG3045	CreA protein
CFM90_07195	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFM90_07210	COG0840	transmembrane signaling receptor activity
CFM90_07220	COG3387	PFAM Glycoside hydrolase 15-related
CFM90_07245	COG0488	(ABC) transporter
CFM90_07250	COG1619	proteins homologs of microcin C7 resistance protein MccF
CFM90_07255	COG0590	tRNA wobble adenosine to inosine editing
CFM90_07260	COG0720	synthase
CFM90_07265	COG0602	queuosine metabolic process
CFM90_07285	COG3550	peptidyl-serine autophosphorylation
CFM90_07305	COG3485	protocatechuate 3,4-dioxygenase
CFM90_07310	COG3485	protocatechuate 3,4-dioxygenase
CFM90_07315	COG0583	DNA-binding transcription factor activity
CFM90_07365	COG0519	Catalyzes the synthesis of GMP from XMP
CFM90_07365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFM90_07380	COG0697	spore germination
CFM90_07390	COG2914	Belongs to the UPF0125 (RnfH) family
CFM90_07395	COG2867	negative regulation of translational initiation
CFM90_07400	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFM90_07405	COG0330	HflC and HflK could
CFM90_07420	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CFM90_07425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFM90_07430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFM90_07435	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFM90_07440	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFM90_07445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFM90_07450	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFM90_07465	COG0750	zinc metalloprotease
CFM90_07470	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFM90_07475	COG0575	Belongs to the CDS family
CFM90_07480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFM90_07485	COG0233	cytoplasmic translational termination
CFM90_07490	COG0528	UMP kinase activity
CFM90_07495	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFM90_07500	COG0052	Belongs to the universal ribosomal protein uS2 family
CFM90_07505	COG0024	Methionine aminopeptidase
CFM90_07510	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFM90_07515	COG1187	pseudouridine synthase activity
CFM90_07525	COG0242	peptide deformylase activity
CFM90_07530	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFM90_07545	COG0596	Alpha beta hydrolase
CFM90_07560	COG2171	N-acyltransferase activity
CFM90_07570	COG1393	Belongs to the ArsC family
CFM90_07575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFM90_07585	COG2890	protein-(glutamine-N5) methyltransferase activity
CFM90_07590	COG0302	gtp cyclohydrolase
CFM90_07615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFM90_07620	COG0601	transmembrane transport
CFM90_07625	COG0747	negative chemotaxis
CFM90_07630	COG4172	Belongs to the ABC transporter superfamily
CFM90_07645	COG0488	(ABC) transporter
CFM90_07650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFM90_07655	COG1683	Conserved Protein
CFM90_07660	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CFM90_07670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFM90_07675	COG0477	Major facilitator Superfamily
CFM90_07680	COG1573	uracil-dna glycosylase
CFM90_07685	COG0456	acetyltransferase
CFM90_07690	COG1214	PFAM Peptidase M22, glycoprotease
CFM90_07710	COG2801	Transposase and inactivated derivatives
CFM90_07760	COG2003	Belongs to the UPF0758 family
CFM90_07775	COG1475	DNA binding
CFM90_07795	COG5489	Protein of unknown function (DUF736)
CFM90_07800	COG1396	sequence-specific DNA binding
CFM90_07830	COG1192	Involved in chromosome partitioning
CFM90_07845	COG4959	Type IV secretory pathway protease TraF
CFM90_07860	COG0583	DNA-binding transcription factor activity
CFM90_07865	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_07870	COG0625	glutathione transferase activity
CFM90_07875	COG0583	DNA-binding transcription factor activity
CFM90_07895	COG4962	Type ii secretion system protein e
CFM90_07900	COG3838	Conjugal transfer protein Trbc
CFM90_07910	COG3451	type IV secretory pathway VirB4
CFM90_07945	COG2814	Major facilitator Superfamily
CFM90_07955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFM90_07970	COG0583	DNA-binding transcription factor activity
CFM90_07980	COG2224	Isocitrate lyase
CFM90_08000	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFM90_08015	COG3275	phosphorelay sensor kinase activity
CFM90_08030	COG0583	DNA-binding transcription factor activity
CFM90_08035	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFM90_08040	COG4208	sulfate ABC transporter
CFM90_08065	COG1116	anion transmembrane transporter activity
CFM90_08070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFM90_08075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFM90_08080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFM90_08085	COG0431	NADPH-dependent FMN reductase
CFM90_08090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CFM90_08095	COG2985	domain, Protein
CFM90_08100	COG0281	malic enzyme
CFM90_08105	COG1304	FMN binding
CFM90_08115	COG4191	Histidine kinase
CFM90_08125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CFM90_08135	COG0542	response to heat
CFM90_08145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFM90_08150	COG0314	molybdopterin synthase activity
CFM90_08155	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CFM90_08160	COG0303	'Molybdopterin
CFM90_08165	COG1573	uracil-dna glycosylase
CFM90_08180	COG0436	Aminotransferase
CFM90_08190	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CFM90_08195	COG2076	Multidrug Resistance protein
CFM90_08200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFM90_08215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFM90_08215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFM90_08225	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFM90_08230	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CFM90_08240	COG0791	NLP P60 protein
CFM90_08245	COG0306	phosphate transporter
CFM90_08255	COG0305	Participates in initiation and elongation during chromosome replication
CFM90_08260	COG0359	binds to the 23S rRNA
CFM90_08265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFM90_08275	COG0360	Binds together with S18 to 16S ribosomal RNA
CFM90_08290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFM90_08305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFM90_08325	COG1024	Enoyl-CoA hydratase
CFM90_08350	COG1566	PFAM secretion protein HlyD family protein
CFM90_08355	COG2814	Major facilitator Superfamily
CFM90_08360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFM90_08365	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFM90_08370	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFM90_08375	COG0195	Participates in both transcription termination and antitermination
CFM90_08375	COG2251	uridine kinase activity
CFM90_08380	COG0779	Required for maturation of 30S ribosomal subunits
CFM90_08385	COG1187	pseudouridine synthase activity
CFM90_08390	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFM90_08400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFM90_08435	COG3278	Belongs to the heme-copper respiratory oxidase family
CFM90_08445	COG2217	Heavy metal translocating P-type atpase
CFM90_08455	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFM90_08460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFM90_08465	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFM90_08470	COG0567	Dehydrogenase, E1 component
CFM90_08475	COG0584	glycerophosphoryl diester phosphodiesterase
CFM90_08480	COG3842	ATPase activity
CFM90_08485	COG0395	ABC-type sugar transport system, permease component
CFM90_08490	COG1175	transmembrane transport
CFM90_08495	COG1653	transport
CFM90_08510	COG2204	response regulator
CFM90_08515	COG3852	Histidine kinase
CFM90_08560	COG1643	Atp-dependent helicase
CFM90_08565	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CFM90_08565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFM90_08570	COG1737	Transcriptional regulator
CFM90_08575	COG0673	inositol 2-dehydrogenase activity
CFM90_08585	COG0673	inositol 2-dehydrogenase activity
CFM90_08595	COG1082	Xylose isomerase domain protein TIM barrel
CFM90_08600	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFM90_08605	COG1129	ABC transporter
CFM90_08615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFM90_08620	COG3962	Belongs to the TPP enzyme family
CFM90_08630	COG3718	enzyme involved in inositol metabolism
CFM90_08640	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CFM90_08650	COG1953	Uracil, thiamine, allantoin
CFM90_08655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFM90_08660	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFM90_08665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CFM90_08670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFM90_08675	COG0557	exoribonuclease II activity
CFM90_08685	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CFM90_08690	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFM90_08695	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFM90_08705	COG0330	HflC and HflK could
CFM90_08710	COG0330	HflC and HflK could
CFM90_08715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFM90_08720	COG1923	regulation of RNA biosynthetic process
CFM90_08725	COG1160	GTP binding
CFM90_08735	COG2976	Protein conserved in bacteria
CFM90_08740	COG0124	histidyl-tRNA synthetase
CFM90_08745	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFM90_08760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CFM90_08765	COG0105	UTP biosynthetic process
CFM90_08775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFM90_08795	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFM90_08800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CFM90_08805	COG3321	synthase
CFM90_08805	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_08805	COG0604	alcohol dehydrogenase
CFM90_08810	COG1902	pentaerythritol trinitrate reductase activity
CFM90_08815	COG1309	transcriptional regulator
CFM90_08820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFM90_08830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFM90_08835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFM90_08850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFM90_08855	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFM90_08860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFM90_08870	COG1074	ATP-dependent DNA helicase activity
CFM90_08885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFM90_08890	COG2204	response regulator
CFM90_08895	COG2197	response regulator
CFM90_08900	COG3228	Belongs to the MtfA family
CFM90_08910	COG0254	rRNA binding
CFM90_08920	COG0534	Mate efflux family protein
CFM90_08955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFM90_08960	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFM90_08965	COG0791	NLP P60 protein
CFM90_08970	COG4172	Belongs to the ABC transporter superfamily
CFM90_08975	COG4239	(ABC) transporter, permease
CFM90_08980	COG4174	ABC transporter (Permease)
CFM90_08985	COG4166	transmembrane transport
CFM90_09000	COG0527	aspartate kinase activity
CFM90_09005	COG0037	tRNA processing
CFM90_09010	COG0825	malonyl-CoA metabolic process
CFM90_09015	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CFM90_09020	COG0215	cysteine-tRNA ligase activity
CFM90_09035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFM90_09040	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFM90_09045	COG1045	serine acetyltransferase
CFM90_09060	COG1396	sequence-specific DNA binding
CFM90_09070	COG2258	MOSC domain
CFM90_09075	COG0840	transmembrane signaling receptor activity
CFM90_09080	COG0840	transmembrane signaling receptor activity
CFM90_09090	COG2814	Major facilitator Superfamily
CFM90_09095	COG0583	DNA-binding transcription factor activity
CFM90_09135	COG4695	Portal protein
CFM90_09330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFM90_09345	COG2850	peptidyl-arginine hydroxylation
CFM90_09355	COG1234	tRNA 3'-trailer cleavage
CFM90_09360	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CFM90_09365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFM90_09375	COG0180	Tryptophanyl-tRNA synthetase
CFM90_09380	COG1994	Peptidase M50
CFM90_09385	COG0009	L-threonylcarbamoyladenylate synthase
CFM90_09390	COG0613	PHP domain protein
CFM90_09395	COG0492	ferredoxin-NADP+ reductase activity
CFM90_09415	COG2267	carboxylic ester hydrolase activity
CFM90_09420	COG2833	Protein of unknown function (DUF455)
CFM90_09430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CFM90_09440	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CFM90_09445	COG0148	phosphopyruvate hydratase activity
CFM90_09455	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CFM90_09460	COG0504	CTP synthase activity
CFM90_09465	COG2267	carboxylic ester hydrolase activity
CFM90_09485	COG2308	Evidence 4 Homologs of previously reported genes of
CFM90_09495	COG0084	hydrolase, TatD family'
CFM90_09500	COG1136	(ABC) transporter
CFM90_09515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFM90_09520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFM90_09530	COG1396	sequence-specific DNA binding
CFM90_09535	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFM90_09545	COG3039	Transposase
CFM90_09560	COG2801	Transposase and inactivated derivatives
CFM90_09580	COG1484	DNA-dependent DNA replication
CFM90_09585	COG4584	PFAM Integrase catalytic
CFM90_09595	COG3039	Transposase
CFM90_09655	COG4974	Belongs to the 'phage' integrase family
CFM90_09675	COG2855	membrane
CFM90_09680	COG0583	DNA-binding transcription factor activity
CFM90_09720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFM90_09720	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFM90_09760	COG0583	DNA-binding transcription factor activity
CFM90_09765	COG2271	Major facilitator Superfamily
CFM90_09805	COG0625	glutathione transferase activity
CFM90_09810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_09820	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_09830	COG2271	Major facilitator Superfamily
CFM90_09840	COG2186	Transcriptional regulator
CFM90_09850	COG0745	RESPONSE REGULATOR receiver
CFM90_09860	COG5002	protein histidine kinase activity
CFM90_09870	COG0745	RESPONSE REGULATOR receiver
CFM90_09895	COG0322	excinuclease ABC activity
CFM90_09905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFM90_09910	COG1472	Belongs to the glycosyl hydrolase 3 family
CFM90_09915	COG0736	holo-[acyl-carrier-protein] synthase activity
CFM90_09920	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFM90_09925	COG1381	Involved in DNA repair and RecF pathway recombination
CFM90_09930	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFM90_09935	COG0571	ribonuclease III activity
CFM90_09945	COG0681	Belongs to the peptidase S26 family
CFM90_09950	COG0481	GTPase activity
CFM90_09960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFM90_09985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFM90_09990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFM90_09995	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_10005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFM90_10010	COG0416	fatty acid biosynthetic process
CFM90_10015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CFM90_10020	COG1399	metal-binding, possibly nucleic acid-binding protein
CFM90_10025	COG0424	maF-like protein
CFM90_10035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFM90_10035	COG0616	signal peptide processing
CFM90_10045	COG0546	phosphoglycolate phosphatase activity
CFM90_10055	COG1530	ribonuclease E activity
CFM90_10060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFM90_10065	COG0746	molybdenum cofactor guanylyltransferase activity
CFM90_10080	COG1322	Protein conserved in bacteria
CFM90_10085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFM90_10100	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFM90_10110	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_10115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFM90_10125	COG3385	transposase activity
CFM90_10140	COG0443	Heat shock 70 kDa protein
CFM90_10145	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CFM90_10155	COG0316	Belongs to the HesB IscA family
CFM90_10160	COG0822	iron-sulfur transferase activity
CFM90_10165	COG1104	cysteine desulfurase activity
CFM90_10175	COG1879	ABC-type sugar transport system periplasmic component
CFM90_10185	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFM90_10190	COG1609	Transcriptional regulator
CFM90_10195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFM90_10205	COG0556	nucleotide-excision repair
CFM90_10220	COG1309	transcriptional regulator
CFM90_10225	COG2878	Part of a membrane complex involved in electron transport
CFM90_10230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFM90_10235	COG0778	Nitroreductase
CFM90_10265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFM90_10305	COG0326	Molecular chaperone. Has ATPase activity
CFM90_10310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFM90_10315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFM90_10330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFM90_10335	COG0625	glutathione transferase activity
CFM90_10350	COG1620	l-lactate permease
CFM90_10370	COG0741	lytic transglycosylase activity
CFM90_10420	COG0513	Belongs to the DEAD box helicase family
CFM90_10425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CFM90_10435	COG0861	Integral membrane protein TerC family
CFM90_10445	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFM90_10455	COG0312	modulator of DNA gyrase
CFM90_10460	COG3028	Belongs to the UPF0307 family
CFM90_10465	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFM90_10470	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CFM90_10475	COG0501	Belongs to the peptidase M48B family
CFM90_10480	COG1162	GTPase activity
CFM90_10490	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CFM90_10495	COG0494	nUDIX hydrolase
CFM90_10500	COG0335	large ribosomal subunit rRNA binding
CFM90_10505	COG0336	Belongs to the RNA methyltransferase TrmD family
CFM90_10510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFM90_10515	COG0228	four-way junction DNA binding
CFM90_10545	COG1522	sequence-specific DNA binding
CFM90_10550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFM90_10555	COG1960	acyl-CoA dehydrogenase activity
CFM90_10575	COG2011	ABC-type metal ion transport system permease component
CFM90_10580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFM90_10585	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFM90_10590	COG2951	lytic endotransglycosylase activity
CFM90_10605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFM90_10610	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CFM90_10620	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CFM90_10630	COG0776	regulation of translation
CFM90_10640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CFM90_10645	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFM90_10650	COG0287	Prephenate dehydrogenase
CFM90_10655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFM90_10660	COG1605	Chorismate mutase
CFM90_10660	COG0077	Prephenate dehydratase
CFM90_10665	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CFM90_10690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFM90_10775	COG3501	Rhs element vgr protein
CFM90_10780	COG0583	DNA-binding transcription factor activity
CFM90_10875	COG3328	transposase activity
CFM90_10895	COG2916	Histone family protein nucleoid-structuring protein H-NS
CFM90_11015	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CFM90_11175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFM90_11185	COG3210	domain, Protein
CFM90_11185	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CFM90_11185	COG3064	Membrane
CFM90_11260	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CFM90_11300	COG4221	oxidoreductase activity
CFM90_11315	COG3039	Transposase
CFM90_11380	COG2963	transposase activity
CFM90_11465	COG1309	transcriptional regulator
CFM90_11470	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_11475	COG0604	alcohol dehydrogenase
CFM90_11505	COG3039	Transposase
CFM90_11625	COG2916	Histone family protein nucleoid-structuring protein H-NS
CFM90_11750	COG0778	Nitroreductase
CFM90_11765	COG4305	rare lipoprotein A
CFM90_11790	COG1280	lysine exporter protein (LysE YggA)
CFM90_11805	COG0425	Belongs to the sulfur carrier protein TusA family
CFM90_11820	COG1942	4-Oxalocrotonate Tautomerase
CFM90_11825	COG0235	Class ii aldolase
CFM90_11830	COG0477	Major facilitator Superfamily
CFM90_11845	COG0330	HflC and HflK could
CFM90_11870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFM90_11875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFM90_11900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFM90_11930	COG4681	YaeQ
CFM90_11945	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CFM90_11955	COG0318	PFAM AMP-dependent synthetase and ligase
CFM90_11960	COG3118	belongs to the thioredoxin family
CFM90_11970	COG2703	oxygen carrier activity
CFM90_11975	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CFM90_11980	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CFM90_11985	COG2982	Protein involved in outer membrane biogenesis
CFM90_12010	COG0259	pyridoxamine-phosphate oxidase activity
CFM90_12015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFM90_12025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFM90_12030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFM90_12040	COG1522	sequence-specific DNA binding
CFM90_12045	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CFM90_12055	COG3483	tryptophan 2,3-dioxygenase activity
CFM90_12065	COG1960	acyl-CoA dehydrogenase activity
CFM90_12070	COG2252	PERMEase
CFM90_12075	COG0450	alkyl hydroperoxide reductase
CFM90_12080	COG4575	ribosome binding
CFM90_12100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFM90_12105	COG0390	transport system, permease component
CFM90_12110	COG0494	nUDIX hydrolase
CFM90_12115	COG2175	clavaminate synthase activity
CFM90_12130	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFM90_12135	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CFM90_12140	COG0745	RESPONSE REGULATOR receiver
CFM90_12150	COG3385	transposase activity
CFM90_12160	COG2391	methyltransferase activity
CFM90_12165	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFM90_12180	COG0823	Involved in the tonB-independent uptake of proteins
CFM90_12200	COG0824	Thioesterase
CFM90_12205	COG4221	oxidoreductase activity
CFM90_12210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFM90_12215	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFM90_12280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFM90_12280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFM90_12295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFM90_12300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFM90_12305	COG0436	Aminotransferase
CFM90_12315	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CFM90_12345	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFM90_12350	COG1902	pentaerythritol trinitrate reductase activity
CFM90_12355	COG1968	undecaprenyl-diphosphatase activity
CFM90_12380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFM90_12385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFM90_12385	COG0425	Belongs to the sulfur carrier protein TusA family
CFM90_12405	COG0859	PFAM glycosyl transferase family 9
CFM90_12420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFM90_12460	COG1088	dTDP-glucose 4,6-dehydratase activity
CFM90_12465	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CFM90_12480	COG0540	Belongs to the ATCase OTCase family
CFM90_12485	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CFM90_12490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFM90_12495	COG1678	Uncharacterized ACR, COG1678
CFM90_12500	COG1187	pseudouridine synthase activity
CFM90_12510	COG0643	Histidine kinase
CFM90_12510	COG2198	Histidine kinase
CFM90_12515	COG0840	transmembrane signaling receptor activity
CFM90_12535	COG1773	rubredoxin
CFM90_12540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CFM90_12545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFM90_12555	COG1704	LemA family
CFM90_12600	COG4964	Belongs to the GSP D family
CFM90_12665	COG4269	membrane
CFM90_12670	COG0459	protein refolding
CFM90_12675	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFM90_12685	COG0443	Heat shock 70 kDa protein
CFM90_12690	COG0604	alcohol dehydrogenase
CFM90_12700	COG2197	response regulator
CFM90_12710	COG0513	Belongs to the DEAD box helicase family
CFM90_12715	COG0583	DNA-binding transcription factor activity
CFM90_12720	COG0656	L-ascorbic acid biosynthetic process
CFM90_12740	COG1073	alpha beta
CFM90_12745	COG2974	May be involved in recombination
CFM90_12770	COG0697	spore germination
CFM90_12810	COG0840	transmembrane signaling receptor activity
CFM90_12815	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFM90_12835	COG2995	paraquat-inducible protein a
CFM90_12840	COG3008	intermembrane lipid transfer
CFM90_12840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CFM90_12850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFM90_12920	COG0738	Major facilitator superfamily
CFM90_12925	COG2027	D-alanyl-D-alanine carboxypeptidase
CFM90_12930	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFM90_12940	COG0546	phosphoglycolate phosphatase activity
CFM90_12950	COG0009	L-threonylcarbamoyladenylate synthase
CFM90_12955	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFM90_12960	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFM90_12965	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFM90_12975	COG0469	pyruvate kinase activity
CFM90_12980	COG0126	phosphoglycerate kinase activity
CFM90_13010	COG0859	PFAM glycosyl transferase family 9
CFM90_13020	COG0429	hydrolase of the alpha beta-hydrolase fold
CFM90_13030	COG4783	chaperone-mediated protein folding
CFM90_13035	COG0315	cyclic pyranopterin monophosphate synthase activity
CFM90_13045	COG4969	Belongs to the N-Me-Phe pilin family
CFM90_13055	COG0861	Integral membrane protein TerC family
CFM90_13065	COG0045	succinate-CoA ligase (ADP-forming) activity
CFM90_13075	COG2137	regulation of response to DNA damage stimulus
CFM90_13080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFM90_13090	COG0642	Histidine kinase
CFM90_13100	COG0477	Major facilitator Superfamily
CFM90_13145	COG0513	Belongs to the DEAD box helicase family
CFM90_13150	COG3039	Transposase
CFM90_13160	COG1960	acyl-CoA dehydrogenase activity
CFM90_13175	COG0318	PFAM AMP-dependent synthetase and ligase
CFM90_13200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFM90_13205	COG1702	phosphate starvation-inducible protein PhoH
CFM90_13210	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFM90_13215	COG4535	Mg2 and Co2 transporter CorC
CFM90_13220	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CFM90_13225	COG0752	glycyl-tRNA synthetase alpha subunit
CFM90_13235	COG0751	glycine-tRNA ligase activity
CFM90_13240	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CFM90_13245	COG0204	Acyl-transferase
CFM90_13255	COG0346	lactoylglutathione lyase activity
CFM90_13260	COG0697	spore germination
CFM90_13265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFM90_13270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFM90_13275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFM90_13280	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CFM90_13300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFM90_13310	COG0006	proline dipeptidase activity
CFM90_13315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFM90_13325	COG4680	protein conserved in bacteria
CFM90_13340	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CFM90_13345	COG0138	bifunctional purine biosynthesis protein purh
CFM90_13355	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CFM90_13365	COG0632	four-way junction helicase activity
CFM90_13370	COG2255	four-way junction helicase activity
CFM90_13385	COG1490	D-aminoacyl-tRNA deacylase activity
CFM90_13390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFM90_13395	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFM90_13400	COG0316	Belongs to the HesB IscA family
CFM90_13415	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFM90_13420	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFM90_13440	COG0418	dihydroorotase activity
CFM90_13450	COG0473	3-isopropylmalate dehydrogenase activity
CFM90_13455	COG0121	glutamine amidotransferase
CFM90_13460	COG1126	abc transporter atp-binding protein
CFM90_13465	COG0765	amino acid transport
CFM90_13470	COG0765	amino acid transport
CFM90_13480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CFM90_13490	COG5265	(ABC) transporter
CFM90_13495	COG1607	acyl-coa hydrolase
CFM90_13500	COG1024	Enoyl-CoA hydratase
CFM90_13505	COG0183	Belongs to the thiolase family
CFM90_13510	COG1024	Enoyl-CoA hydratase
CFM90_13510	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFM90_13515	COG1960	acyl-CoA dehydrogenase activity
CFM90_13530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFM90_13535	COG3568	Endonuclease Exonuclease Phosphatase
CFM90_13540	COG0494	nUDIX hydrolase
CFM90_13550	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFM90_13575	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFM90_13590	COG2226	methyltransferase
CFM90_13600	COG4178	(ABC) transporter
CFM90_13615	COG1238	metal cluster binding
CFM90_13620	COG0700	Nucleoside recognition
CFM90_13635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFM90_13640	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFM90_13640	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFM90_13670	COG0318	PFAM AMP-dependent synthetase and ligase
CFM90_13675	COG3265	gluconokinase activity
CFM90_13690	COG2391	methyltransferase activity
CFM90_13705	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_13720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFM90_13745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFM90_13770	COG0629	single-stranded DNA binding
CFM90_13775	COG2814	Major facilitator Superfamily
CFM90_13795	COG1280	lysine exporter protein (LysE YggA)
CFM90_13800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFM90_13805	COG0693	protein deglycase activity
CFM90_13830	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CFM90_13845	COG1137	ATPase activity
CFM90_13850	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CFM90_13855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFM90_13865	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFM90_13875	COG1660	Displays ATPase and GTPase activities
CFM90_13885	COG1194	a g-specific adenine glycosylase
CFM90_13895	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFM90_13905	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CFM90_13910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFM90_13920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFM90_13925	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFM90_13930	COG0193	aminoacyl-tRNA hydrolase activity
CFM90_13940	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFM90_13945	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFM90_13950	COG0742	ribosomal rna small subunit methyltransferase
CFM90_13955	COG0612	Peptidase, M16
CFM90_13960	COG0612	Peptidase, M16
CFM90_13975	COG0625	glutathione transferase activity
CFM90_13985	COG3707	response regulator
CFM90_13995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFM90_14000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFM90_14005	COG1116	anion transmembrane transporter activity
CFM90_14010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFM90_14015	COG1741	Belongs to the pirin family
CFM90_14030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFM90_14035	COG3385	transposase activity
CFM90_14040	COG1999	signal sequence binding
CFM90_14045	COG0109	protoheme IX farnesyltransferase activity
CFM90_14050	COG1612	heme a metabolic process
CFM90_14080	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CFM90_14085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFM90_14100	COG2226	methyltransferase
CFM90_14105	COG1040	competence protein
CFM90_14115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFM90_14120	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CFM90_14125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFM90_14130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFM90_14135	COG0588	phosphoglycerate mutase activity
CFM90_14140	COG0793	Belongs to the peptidase S41A family
CFM90_14160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFM90_14165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFM90_14175	COG0189	ligase activity
CFM90_14185	COG3385	transposase activity
CFM90_14190	COG0004	ammonium transporteR
CFM90_14215	COG0606	chelatase, subunit chli
CFM90_14235	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CFM90_14245	COG2204	response regulator
CFM90_14250	COG4191	Histidine kinase
CFM90_14255	COG1301	dicarboxylic acid transport
CFM90_14260	COG3411	Ferredoxin
CFM90_14270	COG1686	Belongs to the peptidase S11 family
CFM90_14275	COG2921	Belongs to the UPF0250 family
CFM90_14280	COG0583	DNA-binding transcription factor activity
CFM90_14290	COG0321	lipoyl(octanoyl) transferase activity
CFM90_14295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFM90_14310	COG3511	phospholipase C
CFM90_14340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFM90_14345	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CFM90_14345	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CFM90_14350	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CFM90_14360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CFM90_14385	COG1024	Enoyl-CoA hydratase
CFM90_14415	COG2267	carboxylic ester hydrolase activity
CFM90_14435	COG1410	methionine synthase
CFM90_14435	COG0646	methionine synthase
CFM90_14445	COG2197	response regulator
CFM90_14460	COG3385	transposase activity
CFM90_14475	COG0018	arginyl-trna synthetase
CFM90_14485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFM90_14490	COG4221	oxidoreductase activity
CFM90_14500	COG3547	Transposase (IS116 IS110 IS902 family)
CFM90_14520	COG3039	Transposase
CFM90_14550	COG2329	Antibiotic biosynthesis monooxygenase
CFM90_14560	COG0789	Transcriptional regulator
CFM90_14565	COG1960	acyl-CoA dehydrogenase activity
CFM90_14570	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CFM90_14575	COG0288	reversible hydration of carbon dioxide
CFM90_14580	COG0183	Belongs to the thiolase family
CFM90_14585	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_14590	COG1960	acyl-CoA dehydrogenase activity
CFM90_14605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFM90_14610	COG3012	SEC-C Motif Domain Protein
CFM90_14615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFM90_14625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CFM90_14630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CFM90_14655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFM90_14680	COG0596	Alpha beta hydrolase
CFM90_14715	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFM90_14720	COG0583	DNA-binding transcription factor activity
CFM90_14750	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFM90_14750	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFM90_14750	COG1703	isobutyryl-CoA mutase activity
CFM90_14790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFM90_14800	COG0430	RNA-3'-phosphate cyclase activity
CFM90_14805	COG3541	Predicted nucleotidyltransferase
CFM90_14810	COG1690	Belongs to the RtcB family
CFM90_14820	COG4650	regulator
CFM90_14835	COG1254	Belongs to the acylphosphatase family
CFM90_14855	COG2814	Major facilitator Superfamily
CFM90_14860	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_14865	COG0583	DNA-binding transcription factor activity
CFM90_14870	COG0519	Catalyzes the synthesis of GMP from XMP
CFM90_14870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFM90_14885	COG1733	regulation of RNA biosynthetic process
CFM90_14925	COG3039	Transposase
CFM90_14945	COG0464	growth
CFM90_14970	COG1484	DNA-dependent DNA replication
CFM90_14975	COG4584	PFAM Integrase catalytic
CFM90_15005	COG3039	Transposase
CFM90_15050	COG4584	PFAM Integrase catalytic
CFM90_15055	COG1484	DNA-dependent DNA replication
CFM90_15095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFM90_15100	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFM90_15110	COG0037	tRNA processing
CFM90_15115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFM90_15120	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CFM90_15120	COG0546	phosphoglycolate phosphatase activity
CFM90_15145	COG0493	'glutamate synthase
CFM90_15160	COG0842	Transport permease protein
CFM90_15165	COG1131	(ABC) transporter
CFM90_15180	COG1012	belongs to the aldehyde dehydrogenase family
CFM90_15185	COG0583	DNA-binding transcription factor activity
CFM90_15190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFM90_15215	COG2223	nitrite transmembrane transporter activity
CFM90_15230	COG0697	spore germination
CFM90_15255	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CFM90_15275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFM90_15280	COG4682	membrane
CFM90_15285	COG0708	Exodeoxyribonuclease III
CFM90_15290	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFM90_15300	COG3547	Transposase (IS116 IS110 IS902 family)
CFM90_15305	COG2326	polyphosphate kinase activity
CFM90_15310	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFM90_15315	COG1560	Kdo2-lipid A biosynthetic process
CFM90_15325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFM90_15355	COG0517	IMP dehydrogenase activity
CFM90_15365	COG1522	sequence-specific DNA binding
CFM90_15410	COG1960	acyl-CoA dehydrogenase activity
CFM90_15445	COG2070	2-Nitropropane dioxygenase
CFM90_15450	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFM90_15465	COG2022	thiamine diphosphate biosynthetic process
CFM90_15475	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CFM90_15505	COG0351	phosphomethylpyrimidine kinase
CFM90_15515	COG1785	Belongs to the alkaline phosphatase family
CFM90_15520	COG1785	Belongs to the alkaline phosphatase family
CFM90_15525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CFM90_15530	COG1950	PFAM Membrane protein of
CFM90_15535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CFM90_15545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFM90_15565	COG0617	tRNA 3'-terminal CCA addition
CFM90_15575	COG3246	L-lysine catabolic process to acetate
CFM90_15580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFM90_15605	COG2204	response regulator
CFM90_15610	COG5000	phosphorelay sensor kinase activity
CFM90_15625	COG0501	Belongs to the peptidase M48B family
CFM90_15635	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFM90_15645	COG0242	peptide deformylase activity
CFM90_15650	COG1652	LysM domain
CFM90_15655	COG0758	DNA mediated transformation
CFM90_15670	COG0583	DNA-binding transcription factor activity
CFM90_15675	COG0318	PFAM AMP-dependent synthetase and ligase
CFM90_15680	COG0772	Belongs to the SEDS family
CFM90_15685	COG0768	penicillin binding
CFM90_15700	COG1077	Cell shape determining protein MreB Mrl
CFM90_15705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFM90_15710	COG0154	amidase activity
CFM90_15725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFM90_15735	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CFM90_15740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CFM90_15760	COG0523	cobalamin synthesis protein
CFM90_15765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CFM90_15775	COG0747	negative chemotaxis
CFM90_15780	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFM90_15785	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFM90_15795	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CFM90_15825	COG1595	DNA-templated transcription, initiation
CFM90_15830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFM90_15850	COG2205	protein histidine kinase activity
CFM90_15855	COG0745	RESPONSE REGULATOR receiver
CFM90_15865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFM90_15875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFM90_15885	COG3385	transposase activity
CFM90_15900	COG2879	small protein
CFM90_15905	COG1966	Carbon starvation protein
CFM90_15920	COG3622	Belongs to the hyi family
CFM90_15930	COG0745	RESPONSE REGULATOR receiver
CFM90_15935	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CFM90_15945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFM90_15950	COG3384	dioxygenase
CFM90_15965	COG1309	transcriptional regulator
CFM90_15970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFM90_15980	COG1538	Outer membrane efflux protein
CFM90_15985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFM90_16000	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFM90_16005	COG0706	membrane insertase activity
CFM90_16010	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFM90_16015	COG0594	ribonuclease P activity
CFM90_16020	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFM90_16025	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFM90_16030	COG0592	DNA-directed DNA polymerase activity
CFM90_16045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFM90_16050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFM90_16105	COG1484	DNA-dependent DNA replication
CFM90_16110	COG4584	PFAM Integrase catalytic
CFM90_16120	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CFM90_16145	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFM90_16195	COG1475	DNA binding
CFM90_16230	COG3781	membrane
CFM90_16240	COG0840	transmembrane signaling receptor activity
CFM90_16260	COG1126	abc transporter atp-binding protein
CFM90_16265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFM90_16280	COG0745	RESPONSE REGULATOR receiver
CFM90_16285	COG0642	Histidine kinase
CFM90_16300	COG2814	Major facilitator Superfamily
CFM90_16315	COG1959	2 iron, 2 sulfur cluster binding
CFM90_16340	COG0745	RESPONSE REGULATOR receiver
CFM90_16345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFM90_16365	COG5001	Diguanylate cyclase
CFM90_16365	COG4251	negative regulation of phosphorylation
CFM90_16365	COG2203	Gaf domain
CFM90_16365	COG3706	GGDEF domain
CFM90_16375	COG2205	protein histidine kinase activity
CFM90_16380	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CFM90_16385	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CFM90_16390	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CFM90_16425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFM90_16435	COG1116	anion transmembrane transporter activity
CFM90_16445	COG1254	Belongs to the acylphosphatase family
CFM90_16455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CFM90_16460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFM90_16475	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CFM90_16480	COG2894	cell division
CFM90_16485	COG0850	regulation of cytokinetic process
CFM90_16490	COG0737	Belongs to the 5'-nucleotidase family
CFM90_16500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFM90_16525	COG2154	pterin-4-alpha-carbinolamine dehydratase
CFM90_16530	COG3186	Phenylalanine-4-hydroxylase
CFM90_16545	COG2423	ornithine cyclodeaminase activity
CFM90_16550	COG3047	cAMP biosynthetic process
CFM90_16560	COG2217	Heavy metal translocating P-type atpase
CFM90_16565	COG0789	Transcriptional regulator
CFM90_16570	COG2267	carboxylic ester hydrolase activity
CFM90_16580	COG0411	ABC transporter
CFM90_16595	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFM90_16635	COG3530	Putative quorum-sensing-regulated virulence factor
CFM90_16640	COG0583	DNA-binding transcription factor activity
CFM90_16660	COG0445	tRNA wobble uridine modification
CFM90_16665	COG0357	Ribosomal RNA small subunit methyltransferase G
CFM90_16670	COG1192	Involved in chromosome partitioning
CFM90_16675	COG1475	DNA binding
CFM90_16685	COG0356	it plays a direct role in the translocation of protons across the membrane
CFM90_16695	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFM90_16700	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFM90_16705	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFM90_16710	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFM90_16715	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFM90_16720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFM90_16735	COG1832	CoA-binding protein
CFM90_16755	COG0625	glutathione transferase activity
CFM90_16785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFM90_16790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFM90_16795	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFM90_16795	COG0506	proline dehydrogenase activity
CFM90_16795	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFM90_16800	COG0683	leucine binding
CFM90_16810	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CFM90_16815	COG1297	OPT oligopeptide transporter protein
CFM90_16820	COG1760	l-serine dehydratase
CFM90_16825	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFM90_16825	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFM90_16830	COG0509	glycine decarboxylation via glycine cleavage system
CFM90_16835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFM90_16855	COG0210	DNA helicase
CFM90_16875	COG2197	response regulator
CFM90_16880	COG3916	Acyl-homoserine-lactone synthase
CFM90_16890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFM90_16895	COG2084	Dehydrogenase
CFM90_16905	COG3622	Belongs to the hyi family
CFM90_16910	COG3960	tartronate-semialdehyde synthase activity
CFM90_16915	COG0583	DNA-binding transcription factor activity
CFM90_16930	COG1739	Uncharacterized protein family UPF0029
CFM90_16940	COG1301	dicarboxylic acid transport
CFM90_16945	COG4266	Belongs to the allantoicase family
CFM90_16955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFM90_16980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFM90_16995	COG0792	nuclease activity
CFM90_17010	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFM90_17020	COG4654	Cytochrome c, class I
CFM90_17045	COG2010	Cytochrome c
CFM90_17050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFM90_17055	COG0737	Belongs to the 5'-nucleotidase family
CFM90_17085	COG1484	DNA-dependent DNA replication
CFM90_17090	COG4584	PFAM Integrase catalytic
CFM90_17125	COG1301	dicarboxylic acid transport
CFM90_17130	COG0583	DNA-binding transcription factor activity
CFM90_17135	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CFM90_17140	COG2814	Major facilitator Superfamily
CFM90_17145	COG1280	lysine exporter protein (LysE YggA)
CFM90_17165	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CFM90_17170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFM90_17175	COG0402	S-adenosylhomocysteine deaminase activity
CFM90_17195	COG0529	Catalyzes the synthesis of activated sulfate
CFM90_17210	COG0457	Tetratricopeptide repeat
CFM90_17235	COG0493	'glutamate synthase
CFM90_17250	COG1278	Cold shock
CFM90_17315	COG3706	GGDEF domain
CFM90_17315	COG2203	Gaf domain
CFM90_17315	COG5001	Diguanylate cyclase
CFM90_17315	COG4251	negative regulation of phosphorylation
CFM90_17330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFM90_17340	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_17350	COG0840	transmembrane signaling receptor activity
CFM90_17375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFM90_17385	COG3284	Transcriptional regulator
CFM90_17390	COG1012	belongs to the aldehyde dehydrogenase family
CFM90_17395	COG4303	Ethanolamine ammonia lyase large subunit
CFM90_17400	COG4302	ethanolamine ammonia-lyase activity
CFM90_17405	COG2925	Exonuclease
CFM90_17520	COG1522	sequence-specific DNA binding
CFM90_17555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFM90_17555	COG0475	glutathione-regulated potassium exporter activity
CFM90_17580	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_17590	COG0745	RESPONSE REGULATOR receiver
CFM90_17650	COG4695	Portal protein
CFM90_17800	COG0863	Belongs to the N(4) N(6)-methyltransferase family
CFM90_17890	COG0582	viral genome integration into host DNA
CFM90_17940	COG2197	response regulator
CFM90_17945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFM90_17980	COG2814	Major facilitator Superfamily
CFM90_17985	COG0668	transmembrane transport
CFM90_18000	COG0745	RESPONSE REGULATOR receiver
CFM90_18005	COG2205	protein histidine kinase activity
CFM90_18020	COG0477	Major facilitator Superfamily
CFM90_18025	COG0477	Major facilitator Superfamily
CFM90_18035	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CFM90_18040	COG2336	PFAM SpoVT AbrB
CFM90_18060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFM90_18075	COG0395	ABC-type sugar transport system, permease component
CFM90_18085	COG3842	ATPase activity
CFM90_18090	COG3842	ATPase activity
CFM90_18100	COG1349	DNA-binding transcription factor activity
CFM90_18110	COG2853	Lipoprotein
CFM90_18155	COG0071	Belongs to the small heat shock protein (HSP20) family
CFM90_18205	COG0459	protein refolding
CFM90_18215	COG0415	Belongs to the DNA photolyase family
CFM90_18225	COG0741	lytic transglycosylase activity
CFM90_18240	COG4584	PFAM Integrase catalytic
CFM90_18245	COG1484	DNA-dependent DNA replication
CFM90_18260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFM90_18285	COG1309	transcriptional regulator
CFM90_18305	COG0583	DNA-binding transcription factor activity
CFM90_18310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFM90_18335	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CFM90_18350	COG3547	Transposase (IS116 IS110 IS902 family)
CFM90_18370	COG1674	ftsk spoiiie
CFM90_18390	COG5434	Belongs to the glycosyl hydrolase 28 family
CFM90_18425	COG2207	Transcriptional regulator
CFM90_18470	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFM90_18475	COG4789	Type iii secretion
CFM90_18490	COG4790	Type iii secretion
CFM90_18530	COG0745	RESPONSE REGULATOR receiver
CFM90_18535	COG2197	response regulator
CFM90_18545	COG1595	DNA-templated transcription, initiation
CFM90_18590	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CFM90_18595	COG0840	transmembrane signaling receptor activity
CFM90_18620	COG1056	cytidyltransferase-related domain
CFM90_18620	COG1051	belongs to the nudix hydrolase family
CFM90_18625	COG2271	Major facilitator Superfamily
CFM90_18640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFM90_18645	COG2721	sulfolactate sulfo-lyase activity
CFM90_18655	COG2271	Major facilitator Superfamily
CFM90_18665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFM90_18670	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CFM90_18680	COG0583	DNA-binding transcription factor activity
CFM90_18690	COG0697	spore germination
CFM90_18705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFM90_18710	COG1538	Outer membrane efflux protein
CFM90_18715	COG1309	transcriptional regulator
CFM90_18725	COG0579	oxidoreductase
CFM90_18740	COG4206	TonB-dependent receptor
CFM90_18745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFM90_18760	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFM90_18775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFM90_18785	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CFM90_18790	COG3620	sequence-specific DNA binding
CFM90_18795	COG0587	DNA-directed DNA polymerase activity
CFM90_18810	COG2814	Major facilitator Superfamily
CFM90_18825	COG0436	Aminotransferase
CFM90_18840	COG0300	oxidoreductase activity
CFM90_18840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFM90_18840	COG0318	PFAM AMP-dependent synthetase and ligase
CFM90_18840	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_18840	COG3321	synthase
CFM90_18855	COG2192	nodulation
CFM90_18885	COG0525	valine-tRNA ligase activity
CFM90_18900	COG3916	Acyl-homoserine-lactone synthase
CFM90_18905	COG2197	response regulator
CFM90_19035	COG3501	Rhs element vgr protein
CFM90_19125	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CFM90_19145	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CFM90_19170	COG1730	sister chromatid segregation
CFM90_19175	COG1858	cytochrome C peroxidase
CFM90_19230	COG0411	ABC transporter
CFM90_19260	COG1690	Belongs to the RtcB family
CFM90_19265	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFM90_19290	COG3483	tryptophan 2,3-dioxygenase activity
CFM90_19305	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CFM90_19325	COG1960	acyl-CoA dehydrogenase activity
CFM90_19350	COG3039	Transposase
CFM90_19360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFM90_19365	COG0134	indole-3-glycerol-phosphate synthase activity
CFM90_19370	COG0019	diaminopimelate decarboxylase activity
CFM90_19375	COG0259	pyridoxamine-phosphate oxidase activity
CFM90_19380	COG0583	DNA-binding transcription factor activity
CFM90_19385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFM90_19410	COG1024	Enoyl-CoA hydratase
CFM90_19435	COG2807	transmembrane transport
CFM90_19440	COG2818	Glycosylase
CFM90_19455	COG2814	Major facilitator Superfamily
CFM90_19465	COG1335	isochorismatase
CFM90_19490	COG2132	Multicopper oxidase
CFM90_19495	COG0745	RESPONSE REGULATOR receiver
CFM90_19500	COG5002	protein histidine kinase activity
CFM90_19510	COG1960	acyl-CoA dehydrogenase activity
CFM90_19515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFM90_19530	COG1024	Enoyl-CoA hydratase
CFM90_19535	COG1024	Enoyl-CoA hydratase
CFM90_19540	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CFM90_19545	COG1522	sequence-specific DNA binding
CFM90_19565	COG3251	PFAM MbtH domain protein
CFM90_19570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CFM90_19585	COG4941	Belongs to the sigma-70 factor family
CFM90_19590	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFM90_19625	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CFM90_19630	COG3411	Ferredoxin
CFM90_19645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFM90_19645	COG1648	precorrin-2 dehydrogenase activity
CFM90_19655	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CFM90_19690	COG1797	cobyrinic acid a,c-diamide synthase activity
CFM90_19695	COG0778	Nitroreductase
CFM90_19725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFM90_19730	COG2151	metal-sulfur cluster biosynthetic enzyme
CFM90_19735	COG3396	Phenylacetate-CoA oxygenase
CFM90_19740	COG3460	Phenylacetate-CoA oxygenase
CFM90_19745	COG3396	Phenylacetate-CoA oxygenase
CFM90_19750	COG1404	Belongs to the peptidase S8 family
CFM90_19775	COG0784	Response regulator, receiver
CFM90_19775	COG0835	chemotaxis
CFM90_19785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFM90_19835	COG0300	oxidoreductase activity
CFM90_19860	COG5297	Belongs to the glycosyl hydrolase family 6
CFM90_19945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFM90_19995	COG0402	S-adenosylhomocysteine deaminase activity
CFM90_20050	COG0477	Major facilitator Superfamily
CFM90_20060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CFM90_20085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFM90_20095	COG3039	Transposase
CFM90_20110	COG2910	NAD(P)H-binding
CFM90_20130	COG0443	Heat shock 70 kDa protein
CFM90_20135	COG1914	H( )-stimulated, divalent metal cation uptake system
CFM90_20140	COG3706	GGDEF domain
CFM90_20145	COG3501	Rhs element vgr protein
CFM90_20165	COG0668	transmembrane transport
CFM90_20185	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CFM90_20200	COG0840	transmembrane signaling receptor activity
CFM90_20210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFM90_20255	COG0537	adenosine 5'-monophosphoramidase activity
CFM90_20290	COG3547	Transposase (IS116 IS110 IS902 family)
CFM90_20295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFM90_20320	COG2423	ornithine cyclodeaminase activity
CFM90_20325	COG1522	sequence-specific DNA binding
CFM90_20330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFM90_20340	COG1126	abc transporter atp-binding protein
CFM90_20345	COG0583	DNA-binding transcription factor activity
CFM90_20355	COG1902	pentaerythritol trinitrate reductase activity
CFM90_20405	COG0583	DNA-binding transcription factor activity
CFM90_20430	COG2814	Major facilitator Superfamily
CFM90_20435	COG1126	abc transporter atp-binding protein
CFM90_20455	COG0019	diaminopimelate decarboxylase activity
CFM90_20465	COG4264	IucA IucC family
CFM90_20470	COG4264	IucA IucC family
CFM90_20475	COG2814	Major facilitator Superfamily
CFM90_20480	COG4264	IucA IucC family
CFM90_20485	COG2423	ornithine cyclodeaminase activity
CFM90_20490	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFM90_20505	COG4774	siderophore transport
CFM90_20515	COG2223	nitrite transmembrane transporter activity
CFM90_20565	COG0318	PFAM AMP-dependent synthetase and ligase
CFM90_20590	COG3385	transposase activity
CFM90_20610	COG2203	Gaf domain
CFM90_20610	COG3706	GGDEF domain
CFM90_20610	COG5001	Diguanylate cyclase
CFM90_20610	COG4251	negative regulation of phosphorylation
CFM90_20620	COG3706	GGDEF domain
CFM90_20620	COG4251	negative regulation of phosphorylation
CFM90_20620	COG2203	Gaf domain
CFM90_20620	COG5001	Diguanylate cyclase
CFM90_20655	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFM90_20665	COG1677	Flagellar hook-basal body complex protein FliE
CFM90_20680	COG1846	Transcriptional regulator
CFM90_20705	COG2197	response regulator
CFM90_20735	COG1338	Plays a role in the flagellum-specific transport system
CFM90_20740	COG1987	bacterial-type flagellum assembly
CFM90_20755	COG0204	Acyl-transferase
CFM90_20765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFM90_20775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFM90_20785	COG2986	histidine ammonia-lyase
CFM90_20805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFM90_20815	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_20820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFM90_20835	COG2226	methyltransferase
CFM90_20855	COG1256	bacterial-type flagellum assembly
CFM90_20865	COG1706	bacterial-type flagellum-dependent cell motility
CFM90_20870	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CFM90_20875	COG4786	Flagellar basal body rod
CFM90_20880	COG4787	bacterial-type flagellum-dependent cell motility
CFM90_20885	COG1749	Flagellar hook protein flgE
CFM90_20890	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CFM90_20895	COG1558	bacterial-type flagellum-dependent cell motility
CFM90_20900	COG1815	bacterial-type flagellum-dependent cell motility
CFM90_20920	COG2197	response regulator
CFM90_20925	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_20930	COG2188	Transcriptional regulator
CFM90_20935	COG2916	Histone family protein nucleoid-structuring protein H-NS
CFM90_20970	COG0473	3-isopropylmalate dehydrogenase activity
CFM90_20985	COG1764	response to oxidative stress
CFM90_21010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFM90_21020	COG0789	Transcriptional regulator
CFM90_21045	COG0589	response to stress
CFM90_21060	COG2205	protein histidine kinase activity
CFM90_21065	COG0745	RESPONSE REGULATOR receiver
CFM90_21070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFM90_21075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFM90_21080	COG1538	Outer membrane efflux protein
CFM90_21090	COG1695	Transcriptional regulator
CFM90_21095	COG0583	DNA-binding transcription factor activity
CFM90_21100	COG2070	2-Nitropropane dioxygenase
CFM90_21110	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_21120	COG0840	transmembrane signaling receptor activity
CFM90_21160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFM90_21175	COG1215	transferase activity, transferring glycosyl groups
CFM90_21180	COG1649	PFAM Uncharacterised BCR, COG1649
CFM90_21180	COG0726	polysaccharide deacetylase
CFM90_21190	COG2197	response regulator
CFM90_21205	COG0534	Mate efflux family protein
CFM90_21210	COG0531	amino acid
CFM90_21215	COG3706	GGDEF domain
CFM90_21230	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CFM90_21265	COG3039	Transposase
CFM90_21305	COG0454	-acetyltransferase
CFM90_21305	COG0456	acetyltransferase
CFM90_21315	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CFM90_21330	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CFM90_21350	COG0840	transmembrane signaling receptor activity
CFM90_21360	COG5002	protein histidine kinase activity
CFM90_21360	COG5001	Diguanylate cyclase
CFM90_21360	COG3447	MASE1 domain protein
CFM90_21370	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CFM90_21370	COG1918	ferrous iron import across plasma membrane
CFM90_21390	COG0735	belongs to the Fur family
CFM90_21395	COG3634	alkyl hydroperoxide reductase activity
CFM90_21405	COG4771	TonB-dependent receptor
CFM90_21410	COG3720	iron ion transport
CFM90_21415	COG0297	glycogen (starch) synthase activity
CFM90_21420	COG0366	Alpha amylase catalytic
CFM90_21425	COG0366	Alpha amylase catalytic
CFM90_21430	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFM90_21440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFM90_21445	COG1640	4-alpha-glucanotransferase
CFM90_21530	COG1012	belongs to the aldehyde dehydrogenase family
CFM90_21535	COG1024	Enoyl-CoA hydratase
CFM90_21540	COG1846	Transcriptional regulator
CFM90_21580	COG3039	Transposase
CFM90_21605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFM90_21645	COG3039	Transposase
CFM90_21650	COG3039	Transposase
CFM90_21655	COG3039	Transposase
CFM90_21670	COG1607	acyl-coa hydrolase
CFM90_21685	COG0028	Belongs to the TPP enzyme family
CFM90_21695	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CFM90_21730	COG0730	response to heat
CFM90_21760	COG2706	6-phosphogluconolactonase activity
CFM90_21820	COG1104	cysteine desulfurase activity
CFM90_21855	COG0529	Catalyzes the synthesis of activated sulfate
CFM90_21865	COG3251	PFAM MbtH domain protein
CFM90_21870	COG0534	Mate efflux family protein
CFM90_21880	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CFM90_21910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CFM90_21935	COG4796	Type ii and iii secretion system protein
CFM90_21945	COG4968	Prepilin-type N-terminal cleavage methylation domain
CFM90_21960	COG4677	pectinesterase activity
CFM90_21970	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFM90_21970	COG1902	pentaerythritol trinitrate reductase activity
CFM90_21985	COG0697	spore germination
CFM90_21990	COG3706	GGDEF domain
CFM90_21990	COG0745	RESPONSE REGULATOR receiver
CFM90_22005	COG0210	DNA helicase
CFM90_22020	COG2944	sequence-specific DNA binding
CFM90_22025	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CFM90_22035	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CFM90_22090	COG0288	reversible hydration of carbon dioxide
CFM90_22105	COG0714	Associated with various cellular activities
CFM90_22120	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFM90_22160	COG2814	Major facilitator Superfamily
CFM90_22170	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFM90_22175	COG0477	Major facilitator Superfamily
CFM90_22225	COG1960	acyl-CoA dehydrogenase activity
CFM90_22230	COG1024	Enoyl-CoA hydratase
CFM90_22270	COG2916	Histone family protein nucleoid-structuring protein H-NS
CFM90_22290	COG3039	Transposase
CFM90_22300	COG1881	PFAM PEBP family protein
CFM90_22315	COG0038	chloride channel
CFM90_22330	COG0410	ABC transporter
CFM90_22335	COG0411	ABC transporter
CFM90_22345	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFM90_22355	COG5002	protein histidine kinase activity
CFM90_22355	COG3447	MASE1 domain protein
CFM90_22355	COG5001	Diguanylate cyclase
CFM90_22365	COG4377	Putative membrane peptidase family (DUF2324)
CFM90_22375	COG4191	Histidine kinase
CFM90_22380	COG0477	Major facilitator Superfamily
CFM90_22395	COG1475	DNA binding
CFM90_22400	COG1192	Involved in chromosome partitioning
CFM90_22405	COG1484	DNA-dependent DNA replication
CFM90_22410	COG4584	PFAM Integrase catalytic
CFM90_22415	COG1278	Cold shock
CFM90_22425	COG2252	PERMEase
CFM90_22435	COG2205	protein histidine kinase activity
CFM90_22460	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CFM90_22475	COG2204	response regulator
CFM90_22500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFM90_22510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFM90_22550	COG1595	DNA-templated transcription, initiation
CFM90_22610	COG1609	Transcriptional regulator
CFM90_22615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFM90_22620	COG4214	carbohydrate transport
CFM90_22625	COG1129	ABC transporter
CFM90_22630	COG4213	ABC transporter substrate-binding protein
CFM90_22670	COG4251	negative regulation of phosphorylation
CFM90_22670	COG5001	Diguanylate cyclase
CFM90_22670	COG3706	GGDEF domain
CFM90_22670	COG2203	Gaf domain
CFM90_22675	COG2205	protein histidine kinase activity
CFM90_22675	COG0784	Response regulator, receiver
CFM90_22685	COG5295	Hep Hag repeat protein
CFM90_22685	COG5295	Hep Hag repeat protein
CFM90_22690	COG3969	phosphoadenosine phosphosulfate
CFM90_22700	COG1475	DNA binding
CFM90_22710	COG2721	sulfolactate sulfo-lyase activity
CFM90_22715	COG2271	Major facilitator Superfamily
CFM90_22725	COG0473	3-isopropylmalate dehydrogenase activity
CFM90_22730	COG1012	belongs to the aldehyde dehydrogenase family
CFM90_22790	COG1538	Outer membrane efflux protein
CFM90_22795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFM90_22810	COG2814	Major facilitator Superfamily
CFM90_22815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_22835	COG0583	DNA-binding transcription factor activity
CFM90_22845	COG1012	belongs to the aldehyde dehydrogenase family
CFM90_22850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFM90_22915	COG2197	response regulator
CFM90_22920	COG0010	Belongs to the arginase family
CFM90_22925	COG0765	amino acid transport
CFM90_22935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFM90_22950	COG2271	Major facilitator Superfamily
CFM90_22995	COG0436	Aminotransferase
CFM90_23005	COG3039	Transposase
CFM90_23020	COG1845	cytochrome c oxidase, subunit III
CFM90_23030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFM90_23035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFM90_23050	COG0589	response to stress
CFM90_23060	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFM90_23085	COG0745	RESPONSE REGULATOR receiver
CFM90_23090	COG0642	Histidine kinase
CFM90_23095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFM90_23125	COG3210	domain, Protein
CFM90_23140	COG3210	domain, Protein
CFM90_23140	COG3064	Membrane
CFM90_23140	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CFM90_23150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFM90_23170	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
CFM90_23195	COG0705	Rhomboid family
CFM90_23200	COG3706	GGDEF domain
CFM90_23200	COG0745	RESPONSE REGULATOR receiver
CFM90_23250	COG0583	DNA-binding transcription factor activity
CFM90_23270	COG0745	RESPONSE REGULATOR receiver
CFM90_23270	COG3706	GGDEF domain
CFM90_23285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFM90_23290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CFM90_23295	COG2188	Transcriptional regulator
CFM90_23345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFM90_23345	COG4651	solute:proton antiporter activity
CFM90_23370	COG2192	nodulation
CFM90_23460	COG0667	Aldo Keto reductase
CFM90_23500	COG1136	(ABC) transporter
CFM90_23500	COG0577	efflux transmembrane transporter activity
CFM90_23505	COG1136	(ABC) transporter
CFM90_23540	COG2267	carboxylic ester hydrolase activity
CFM90_23545	COG0477	Major facilitator Superfamily
CFM90_23580	COG1360	Flagellar Motor Protein
CFM90_23585	COG0745	RESPONSE REGULATOR receiver
CFM90_23595	COG0835	chemotaxis
CFM90_23600	COG0840	transmembrane signaling receptor activity
CFM90_23605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CFM90_23610	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CFM90_23615	COG2201	protein-glutamate methylesterase activity
CFM90_23620	COG0745	RESPONSE REGULATOR receiver
CFM90_23625	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CFM90_23635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_23640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFM90_23645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFM90_23650	COG2271	Major facilitator Superfamily
CFM90_23655	COG1309	transcriptional regulator
CFM90_23660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFM90_23665	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFM90_23680	COG1191	sigma factor activity
CFM90_23705	COG0762	integral membrane protein
CFM90_23715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFM90_23725	COG2824	Alkylphosphonate utilization operon protein PhnA
CFM90_23760	COG2831	hemolysin activation secretion protein
CFM90_23820	COG4263	nitrous-oxide reductase activity
CFM90_23835	COG0204	Acyl-transferase
CFM90_23840	COG0567	Dehydrogenase, E1 component
CFM90_23845	COG0840	transmembrane signaling receptor activity
CFM90_23865	COG3039	Transposase
CFM90_23870	COG0251	oxidation-reduction process
CFM90_23885	COG0640	Transcriptional regulator
CFM90_23895	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_23900	COG1522	sequence-specific DNA binding
CFM90_23910	COG0251	oxidation-reduction process
CFM90_23965	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CFM90_23970	COG0410	ABC transporter
CFM90_23990	COG0683	leucine binding
CFM90_24010	COG3766	membrane
CFM90_24030	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CFM90_24060	COG4968	Prepilin-type N-terminal cleavage methylation domain
CFM90_24065	COG1609	Transcriptional regulator
CFM90_24075	COG1621	beta-fructofuranosidase activity
CFM90_24100	COG0114	fumarate hydratase activity
CFM90_24105	COG0477	Major facilitator Superfamily
CFM90_24135	COG1742	UPF0060 membrane protein
CFM90_24140	COG0668	transmembrane transport
CFM90_24170	COG0730	response to heat
CFM90_24185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFM90_24190	COG0730	response to heat
CFM90_24195	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CFM90_24215	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFM90_24235	COG3550	peptidyl-serine autophosphorylation
CFM90_24270	COG0251	oxidation-reduction process
CFM90_24280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFM90_24285	COG1294	oxidase, subunit
CFM90_24290	COG1271	oxidase subunit
CFM90_24300	COG2951	lytic endotransglycosylase activity
CFM90_24345	COG0473	3-isopropylmalate dehydrogenase activity
CFM90_24345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFM90_24355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFM90_24380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFM90_24390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFM90_24395	COG0840	transmembrane signaling receptor activity
CFM90_24400	COG2223	nitrite transmembrane transporter activity
CFM90_24405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFM90_24410	COG2146	nitrite reductase [NAD(P)H] activity
CFM90_24415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFM90_24420	COG0243	molybdopterin cofactor binding
CFM90_24435	COG0534	Mate efflux family protein
CFM90_24450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFM90_24460	COG0840	transmembrane signaling receptor activity
CFM90_24465	COG5001	Diguanylate cyclase
CFM90_24465	COG3300	MHYT domain
CFM90_24470	COG1271	oxidase subunit
CFM90_24475	COG1294	oxidase, subunit
CFM90_24500	COG1538	Outer membrane efflux protein
CFM90_24520	COG0745	RESPONSE REGULATOR receiver
CFM90_24540	COG2197	response regulator
CFM90_24545	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFM90_24550	COG0800	Aldolase
CFM90_24565	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CFM90_24590	COG2274	protein secretion by the type I secretion system
CFM90_24620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFM90_24620	COG2205	protein histidine kinase activity
CFM90_24650	COG1858	cytochrome C peroxidase
CFM90_24655	COG1253	flavin adenine dinucleotide binding
CFM90_24675	COG1858	cytochrome C peroxidase
CFM90_24705	COG2205	protein histidine kinase activity
CFM90_24710	COG0745	RESPONSE REGULATOR receiver
CFM90_24725	COG3813	Protein conserved in bacteria
CFM90_24745	COG3300	MHYT domain
CFM90_24745	COG5001	Diguanylate cyclase
CFM90_24760	COG1942	4-Oxalocrotonate Tautomerase
CFM90_24765	COG2267	carboxylic ester hydrolase activity
CFM90_24780	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFM90_24785	COG4149	molybdate abc transporter
CFM90_24790	COG2066	Belongs to the glutaminase family
CFM90_24800	COG2197	response regulator
CFM90_24810	COG3501	Rhs element vgr protein
CFM90_24820	COG3209	COG3209 Rhs family protein
CFM90_24850	COG0640	Transcriptional regulator
CFM90_24855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFM90_24860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFM90_24870	COG1064	alcohol dehydrogenase
CFM90_24895	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CFM90_24920	COG1064	alcohol dehydrogenase
CFM90_24930	COG0583	DNA-binding transcription factor activity
CFM90_24940	COG3321	synthase
CFM90_24940	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_24940	COG0604	alcohol dehydrogenase
CFM90_24950	COG2030	dehydratase
CFM90_24955	COG1733	regulation of RNA biosynthetic process
CFM90_24995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFM90_25005	COG0583	DNA-binding transcription factor activity
CFM90_25020	COG1764	response to oxidative stress
CFM90_25025	COG1846	Transcriptional regulator
CFM90_25035	COG1877	trehalose-phosphatase activity
CFM90_25045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFM90_25055	COG0840	transmembrane signaling receptor activity
CFM90_25070	COG2197	response regulator
CFM90_25110	COG4964	Belongs to the GSP D family
CFM90_25165	COG0673	inositol 2-dehydrogenase activity
CFM90_25220	COG0673	inositol 2-dehydrogenase activity
CFM90_25230	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_25235	COG4689	acetoacetate decarboxylase
CFM90_25260	COG1278	Cold shock
CFM90_25265	COG3158	transport of potassium into the cell
CFM90_25270	COG5001	Diguanylate cyclase
CFM90_25270	COG3300	MHYT domain
CFM90_25275	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFM90_25285	COG0243	molybdopterin cofactor binding
CFM90_25310	COG3039	Transposase
CFM90_25320	COG0745	RESPONSE REGULATOR receiver
CFM90_25355	COG3220	belongs to the UPF0276 family
CFM90_25395	COG0840	transmembrane signaling receptor activity
CFM90_25440	COG1596	polysaccharide export
CFM90_25445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFM90_25450	COG0489	protein tyrosine kinase activity
CFM90_25450	COG3206	protein involved in exopolysaccharide biosynthesis
CFM90_25455	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CFM90_25460	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CFM90_25465	COG2244	polysaccharide biosynthetic process
CFM90_25480	COG0110	maltose O-acetyltransferase activity
CFM90_25500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFM90_25510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFM90_25560	COG0583	DNA-binding transcription factor activity
CFM90_25570	COG1301	dicarboxylic acid transport
CFM90_25575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFM90_25595	COG1999	signal sequence binding
CFM90_25610	COG1454	alcohol dehydrogenase
CFM90_25615	COG0477	Major facilitator Superfamily
CFM90_25620	COG0352	thiamine-phosphate diphosphorylase activity
CFM90_25640	COG2197	response regulator
CFM90_25645	COG3850	Histidine kinase
CFM90_25650	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFM90_25655	COG2181	nitrate reductase activity
CFM90_25660	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CFM90_25665	COG1140	nitrate reductase beta subunit
CFM90_25670	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFM90_25675	COG2223	nitrite transmembrane transporter activity
CFM90_25735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFM90_25740	COG3604	Transcriptional regulator
CFM90_25745	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CFM90_25785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFM90_25790	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CFM90_25795	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CFM90_25800	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CFM90_25805	COG1063	alcohol dehydrogenase
CFM90_25810	COG1028	Short-chain dehydrogenase reductase Sdr
CFM90_25815	COG3265	gluconokinase activity
CFM90_25825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFM90_25840	COG0511	ligase activity, forming carbon-carbon bonds
CFM90_25850	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CFM90_25855	COG1984	allophanate hydrolase subunit 2
CFM90_25865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFM90_25870	COG4221	oxidoreductase activity
CFM90_25875	COG0765	amino acid transport
CFM90_25880	COG0765	amino acid transport
CFM90_25885	COG1126	abc transporter atp-binding protein
CFM90_25890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFM90_25910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFM90_25940	COG2801	Transposase and inactivated derivatives
CFM90_25950	COG0745	RESPONSE REGULATOR receiver
CFM90_25965	COG0071	Belongs to the small heat shock protein (HSP20) family
CFM90_26015	COG0459	protein refolding
CFM90_26025	COG0415	Belongs to the DNA photolyase family
CFM90_26035	COG3210	domain, Protein
CFM90_26045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFM90_26050	COG3039	Transposase
CFM90_26065	COG3850	Histidine kinase
CFM90_26070	COG2197	response regulator
CFM90_26140	COG2948	multi-organism process
CFM90_26190	COG1484	DNA-dependent DNA replication
CFM90_26195	COG4584	PFAM Integrase catalytic
CFM90_26315	COG4584	PFAM Integrase catalytic
CFM90_26320	COG1484	DNA-dependent DNA replication
CFM90_26515	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CFM90_26560	COG1192	Involved in chromosome partitioning